title: [Determination of zinc and copper in patients with liver cirrhosis of diverse clinical severity].
abstract: Zinc and copper levels in the blood and urine of 44 liver cirrhosis patients and 10 healthy volunteers are reported. The clinical severity of the liver disease (according to the Child classification system) was correlated with the levels of the two metals. An attempt was also made to break down the parameters on which the Child System in based in order to contribute to the pathogenic interpretation of changing zinc levels in liver disease patients. The results show a significant reduction in zinc in the blood but an increase in the urine in the various degrees of liver damage. A connection was also noted between low blood zinc and encephalopathy.
authors.affiliation: III Divisione di Medicina Generale, Ospedale Maggiore Novara.
authors.forename: M
authors.initials: M
authors.lastname: Sartori
authors.forename: M
authors.initials: M
authors.lastname: Calgaro
authors.forename: M
authors.initials: M
authors.lastname: Campanini
authors.forename: G P
authors.initials: GP
authors.lastname: Carnevale Schianca
authors.forename: G G
authors.initials: GG
authors.lastname: De Simone
authors.forename: M
authors.initials: M
authors.lastname: Dugnani
authors.forename: G
authors.initials: G
authors.lastname: Pozzoli
mesh_terms: D003300:Copper / Q000032:analysis* / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000145:classification / Q000175:diagnosis / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D013054:Spectrophotometry, Atomic; D015032:Zinc / Q000032:analysis* / Q000097:blood / Q000652:urine
chemical_list: D003300:Copper; D015032:Zinc
vernacular_title: Dosaggio di zinco e rame in pazienti con cirrosi epatica di diversa gravità clinica.