title: An optimal design problem in rhythmometry.
abstract: A trigonometric regression model is assumed for a problem involving circadian rhythm exhibited by peak expiratory flow. Experimental designs are sought with a view to estimating a particular nonlinear function of the parameters. Both optimal and nonoptimal, but more practicable, designs are derived and their relative efficiencies are established.
authors.affiliation: Department of Statistics, University of Glasgow, Scotland, U.K.
authors.forename: C P
authors.initials: CP
authors.lastname: Kitsos
authors.forename: D M
authors.initials: DM
authors.lastname: Titterington
authors.forename: B
authors.initials: B
authors.lastname: Torsney
mesh_terms: D002940:Circadian Rhythm; D008433:Mathematics; D008954:Models, Biological; D010366:Peak Expiratory Flow Rate