title: The ocular ischemic syndrome. Clinical, fluorescein angiographic and carotid angiographic features.
abstract: The records of 43 consecutive patients (51 eyes) with the ocular ischemic syndrome (ocular symptoms and signs attributable to severe carotid artery obstruction) were studied in a retrospective fashion. Men comprised 67% of the group and the mean age at presentation was 64.5 years. In the anterior segment, neovascularization of the iris was observed in 66% of eyes and iritis was noted in 18%. Posterior segment signs included narrowed retinal arteries and dilated, but not tortuous, retinal veins. Mid-peripheral retinal hemorrhages were seen in 80% of eyes, posterior segment neovascularization was observed in 37%, and a cherry red spot was noted in 12%. Fluorescein angiography commonly revealed delayed choroidal and retinal filling, while electroretinography generally demonstrated a reduction in the amplitude of both the a- and b-waves.
authors.affiliation: Retina Vascular Unit, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA.
authors.forename: G C
authors.initials: GC
authors.lastname: Brown
authors.forename: L E
authors.initials: LE
authors.lastname: Magargal
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000150:complications; D005123:Eye / Q000098:blood supply*; D005260:Female; D005451:Fluorescein Angiography; D015355:Glaucoma, Neovascular / Q000150:complications; D006801:Humans; D007499:Iris Diseases / Q000150:complications; D007511:Ischemia / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010146:Pain; D012164:Retinal Diseases / Q000150:complications; D014605:Uveitis / Q000150:complications