title: Trisomy 18 associated with ectopia cordis and occipital meningocele.
abstract: A premature infant presented with ectopia cordis, occipital meningocele, and manifestations of trisomy 18; cytogenetic analysis confirmed a 47,XX,+18 chromosome constitution. While most cases of ectopia cordis appear as isolated, sporadic defects, careful evaluation is warranted to detect evidence of an associated chromosome abnormality.
authors.affiliation: Department of Pediatrics, University of Texas Health Science Center, San Antonio 78284.
authors.forename: D
authors.initials: D
authors.lastname: Bick
authors.forename: R I
authors.initials: RI
authors.lastname: Markowitz
authors.forename: A
authors.initials: A
authors.lastname: Horwich
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006330:Heart Defects, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008588:Meningocele / Q000235:genetics*; D014314:Trisomy