title: Malignant glioma of the optic chiasm eight years after radiotherapy for prolactinoma.
abstract: A 41-year-old man had rapidly progressive visual loss caused by a malignant glioma that developed in the optic chiasm eight years after radiation therapy for a recurrent prolactinoma. Radiation-induced glioma should be considered as a cause of progressive visual loss in patients who have received irradiation in the region of the sella turcica.
authors.affiliation: Section of Neuropathology, Yale University School of Medicine, New Haven, Conn 06510.
authors.forename: T J
authors.initials: TJ
authors.lastname: Hufnagel
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: R
authors.initials: R
authors.lastname: Lesser
authors.forename: J M
authors.initials: JM
authors.lastname: Miller
authors.forename: J J
authors.initials: JJ
authors.lastname: Abrahams
authors.forename: J
authors.initials: J
authors.lastname: Piepmeier
authors.forename: E E
authors.initials: EE
authors.lastname: Manuelidis
mesh_terms: D000328:Adult; D001766:Blindness / Q000209:etiology*; D003390:Cranial Nerve Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D005910:Glioma / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000150:complications; D009897:Optic Chiasm / Q000473:pathology; D010911:Pituitary Neoplasms / Q000532:radiotherapy*; D015175:Prolactinoma / Q000532:radiotherapy*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014794:Visual Fields