title: Peripheral neuroepithelioma in childhood. Immunohistochemical demonstration of epithelial differentiation.
abstract: Peripheral neuroepithelioma arising from the chest wall of a 4-year-old girl is described. She died of local recurrence 15 months after surgery. Light- and electron-microscopic as well as immunohistochemical findings confirmed the neuroectodermal nature of the tumor. A distinctive histologic feature was the presence of clustered epitheliallike cells, which immunohistochemically stained positive for both keratin and carcinoembryonic antigen. The epithelial nature of these peculiar cells is presented.
authors.affiliation: Department of Pathology, Tokai University School of Medicine, Isehara, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Shinoda
authors.forename: Y
authors.initials: Y
authors.lastname: Tsutsumi
authors.forename: J
authors.initials: J
authors.lastname: Hata
authors.forename: S
authors.initials: S
authors.lastname: Yokoyama
mesh_terms: D002272:Carcinoembryonic Antigen / Q000032:analysis; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002675:Child, Preschool; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000032:analysis / Q000473:pathology*; D013899:Thoracic Neoplasms / Q000032:analysis / Q000473:pathology*
chemical_list: D002272:Carcinoembryonic Antigen