title: Synovial lymphocyte responses to microbial antigens differentiate the arthritis of enteric reactive arthritis from the arthritis of inflammatory bowel disease.
abstract: Synovial lymphocyte responses to microbial antigens were measured by the 3H-thymidine uptake method in 5 patients with bacteriologically defined enteric reactive arthritis and 7 patients with arthritis associated with inflammatory bowel disease. All the patients with enteric reactive arthritis had maximal synovial lymphocyte responses to the relevant enteric antigen; in contrast, the synovial lymphocytes of the patients with inflammatory bowel disease all responded maximally to nonenteric antigens.
authors.affiliation: Department of Medicine, University of British Columbia, Vancouver, Canada.
authors.forename: D K
authors.initials: DK
authors.lastname: Ford
authors.forename: M
authors.initials: M
authors.lastname: Schulzer
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology*; D001170:Arthritis, Infectious / Q000209:etiology*; D001424:Bacterial Infections / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis; D007410:Intestinal Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D007422:Intestines / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D013582:Synovial Fluid / Q000166:cytology*
chemical_list: D000942:Antigens, Bacterial