title: Neurological manifestations of the hypereosinophilic syndrome (HES).
abstract: The hypereosinophilic syndrome (HES) is a rare disease, characterized by a long lasting hypereosinophilia of the blood and the marrow and by the presence of varying internal symptoms and frequent neurological signs. These latter can be as well central: encephalomalacy, organic psycho-syndrome, as peripheral: polyneuropathy or mononeuropathia multiplex, autonomic neuropathy and in rare cases a polymyositis. The disease clinically resembles very to periarteriitis nodosa (PAN). However, the prognosis of HES is far better, especially when early recognized and adequately treated.
authors.affiliation: General Hospital (Maasland Ziekenhuis) Sittard, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Prick
authors.forename: A A
authors.initials: AA
authors.lastname: Gabreëls-Festen
authors.forename: J J
authors.initials: JJ
authors.lastname: Korten
authors.forename: T W
authors.initials: TW
authors.lastname: van der Wiel
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D004802:Eosinophilia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006801:Humans; D013577:Syndrome
chemical_list: D000305:Adrenal Cortex Hormones