title: Treatment of acquired nystagmus with botulinum A toxin.
abstract: We injected botulinum A toxin into the retrobulbar space of one eye each in two patients who had acquired nystagmus with oscillopsia and decreased vision. After injection of 25 units of botulinum A toxin, visual acuity improved from 20/80 to 20/30 in one patient, and both patients were able to read and watch television. Improved vision lasted from five to 13 weeks. No adverse side effects were observed after a total of five injections in each patient.
authors.affiliation: Department of Ophthalmology, Indiana University School of Medicine, Indianapolis.
authors.forename: E M
authors.initials: EM
authors.lastname: Helveston
authors.forename: A E
authors.initials: AE
authors.lastname: Pogrebniak
mesh_terms: D001905:Botulinum Toxins / Q000627:therapeutic use*; D002544:Cerebral Infarction / Q000150:complications; D005123:Eye; D005260:Female; D006801:Humans; D007267:Injections; D008875:Middle Aged; D009759:Nystagmus, Pathologic / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D012008:Recurrence; D014785:Vision, Ocular / Q000187:drug effects; D014792:Visual Acuity
chemical_list: D001905:Botulinum Toxins