title: On the interaction between xanthine oxidase and actin.
abstract: Xanthine oxidase increases the rate of actin polymerization. This occurs at oxidase concentrations as low as 40 nM provided the concentration of the polymerizing agent is low (0.5 mM MgCl2). In the presence of 0.1 M KCl plus 1 mM MgCl2 as the polymerizing agents, xanthine oxidase does not affect the rate of the polymerization but increases significantly the rate of the conversion of F(ATP)actin into F(ADP.Pi)actin and probably also the rate of the orthophosphate release.
authors.affiliation: Istituto di Chimica Biologica, Università di Ferrara, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Lanzara
authors.forename: F
authors.initials: F
authors.lastname: Cervellati
authors.forename: E
authors.initials: E
authors.lastname: Grazi
mesh_terms: D000199:Actins / Q000378:metabolism* / Q000648:ultrastructure; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D006868:Hydrolysis; D066298:In Vitro Techniques; D008854:Microscopy, Electron; D010710:Phosphates / Q000378:metabolism; D011108:Polymers / Q000378:metabolism; D014969:Xanthine Oxidase / Q000378:metabolism*
chemical_list: D000199:Actins; D010710:Phosphates; D011108:Polymers; D000255:Adenosine Triphosphate; D014969:Xanthine Oxidase