Clinicopathologic correlation of pigmented epiretinal membranes.
We performed clinicopathologic correlation on ten surgically removed pigmented epiretinal membranes causing macular pucker. All cases occurred in eyes with existing retinal holes or tears, including eight cases of macular pucker after previous retinal detachment. These cases probably represented a limited form of proliferative vitreoretinopathy. All membranes contained pigment epithelial cells with polarity, basement membrane, and melanosomes. Cytoplasmic melanin granules accounted for the clinical feature of pigmentation in these eyes.
Cherfan
G M
GM
Eye Pathology Laboratory, Johns Hopkins Hospital, Baltimore, MD 21205.
Smiddy
W E
WE
Michels
R G
RG
de la Cruz
Z
Z
Wilkinson
C P
CP
Green
W R
WR
D001253:Astrocytes / Q000473:pathology; D003094:Collagen / Q000378:metabolism; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D008566:Membranes / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D008854:Microscopy, Electron; D008875:Middle Aged; D009887:Ophthalmoscopy; D010858:Pigmentation; D011183:Postoperative Complications; D012163:Retinal Detachment / Q000601:surgery; D012164:Retinal Diseases / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D014821:Vitrectomy
D003094:Collagen