title: Transient blindness and seizure associated with cisplatin therapy.
abstract: A 38-year-old woman with adenocarcinoma of unknown origin was treated with cisplatin and etoposide. After the 4th course of chemotherapy she complained of blindness and had a seizure with spontaneous recovery in 4 days. The relationship between these events and the known neurotoxicity of other heavy metals indicate cisplatin as a possible etiologic factor.
authors.affiliation: Clinica Medica Generale, Università di Milano, Italy.
authors.forename: M T
authors.initials: MT
authors.lastname: Cattaneo
authors.forename: V
authors.initials: V
authors.lastname: Filipazzi
authors.forename: E
authors.initials: E
authors.lastname: Piazza
authors.forename: E
authors.initials: E
authors.lastname: Damiani
authors.forename: G
authors.initials: G
authors.lastname: Mancarella
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy; D000328:Adult; D001766:Blindness / Q000139:chemically induced*; D002945:Cisplatin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D012640:Seizures / Q000139:chemically induced*
chemical_list: D002945:Cisplatin