title: [Reactions of the neuronal networks with various mechanisms for the termination of activity to external de- and hyperpolarization exposures].
abstract: Responses of the stochastically organized uniform neuronal networks as well as responses of networks with pre- and postsynaptic inhibition to external de- and hyperpolarizing effects of different intensity and temporal structure were compared by means of the mathematical simulation model. In the networks with pre- and postsynaptic inhibition in comparison with uniform neuronal networks a region of long-term depolarizing effects with possible monitoring of the activity of neuronal networks parameters is enlarged. The effect of short-term de- and hyperpolarizing influences in neuronal networks depends on the neuronal network activity level oscillations. Depolarizing effects may shorten the activity of neuronal networks, while hyperpolarizing influences may prolong the activity. An effect of reducing the activity of neuronal networks due to depolarizing influences is more noticeable in the networks with pre- and postsynaptic inhibition. Coming from the results obtained a conclusion is made that the presence of additional negative feedback circuits in a form of presynaptic or postsynaptic inhibition networks contributes to control improvement of the mechanism, which terminates the network activity.
authors.forename: A M
authors.initials: AM
authors.lastname: Degtiarenko
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology; D003198:Computer Simulation; D006801:Humans; D008959:Models, Neurological; D009411:Nerve Endings / Q000502:physiology; D009433:Neural Inhibition; D009434:Neural Pathways / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D013269:Stochastic Processes; D013569:Synapses / Q000502:physiology; D013997:Time Factors
vernacular_title: Reaktsii neĭronnykh seteĭ s razlichnymi mekhanizmami prekrashcheniia aktivnosti na vneshnie de- i giperpoliarizuiushchie vozdeĭstviia.