Transient tic disorder and the spectrum of Tourette's syndrome.
Transient tic disorder (TTD) has not generally been considered part of the spectrum of Tourette's syndrome (TS). We studied a large kindred affected by TS and identified two family members with TTD who are very likely obligate carriers of the TS gene. Our observations indicate that TTD is a possible expression of the TS gene and that individuals with TTD may transmit TS to their offspring.
Kurlan
R
R
Department of Neurology, University of Rochester, School of Medicine.
Behr
J
J
Medved
L
L
Como
P
P
D000328:Adult; D005260:Female; D006579:Heterozygote; D006801:Humans; D008297:Male; D010375:Pedigree; D013981:Tic Disorders / Q000235:genetics*; D005879:Tourette Syndrome / Q000235:genetics*