The effect of truncal vagotomy on the bicarbonate-ion secretion of the stomach in rat.
The effect of truncal vagotomy on the gastric bicarbonate-ion, H-ion and chloride-ion secretions of the rat was studied experimentally. In the first half hour after truncal vagotomy, besides the known decrease of the H-ion, also the bicarbonate-ion and chloride-ion secretions were found reduced. The decrease in bicarbonate ion secretion was smaller as compared to the H-ion secretion. After two hours, there was no difference in bicarbonate-ion and chloride-ion secretions as compared to the controls and to the vagotomized groups. According to their results, following truncal vagotomy applied in the surgical management of ulcer, the bicarbonate-ion secretion of the stomach decreases immediately after operation. This decrease is, however, only transitory the bicarbonate-ion secretion becoming normal within a short time.
Dubecz
S
S
3rd Department of Surgery, Semmelweis University Medical School, Budapest, Hungary.
Szombath
D
D
Sándor
J
J
Gáti
T
T
D000818:Animals; D001639:Bicarbonates / Q000378:metabolism*; D005745:Gastric Acidity Determination; D005753:Gastric Mucosa / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000294:innervation*; D015167:Vagotomy, Truncal
D001639:Bicarbonates