A unique chromosome translocation, t(7;15), in a pediatric patient with pre-B-cell lymphoma presenting as a primary tumor of bone.
We report here the clinical and cytogenetic findings in a 3-year-old girl with pre-B-cell acute lymphoblastic leukemia presenting as a primary tumor of bone. A unique translocation t(7;15)(q22;q14-15) is described.
Biegel
J A
JA
Division of Genetics, Children's Hospital of Philadelphia, PA 19104.
Belasco
J B
JB
Emanuel
B S
BS
D001859:Bone Neoplasms / Q000175:diagnosis; D002051:Burkitt Lymphoma / Q000175:diagnosis / Q000235:genetics*; D002675:Child, Preschool; D002871:Chromosome Banding; D002884:Chromosomes, Human, Pair 15; D002897:Chromosomes, Human, Pair 7; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007621:Karyotyping; D011289:Preleukemia / Q000175:diagnosis / Q000235:genetics*; D012512:Sarcoma, Ewing / Q000175:diagnosis; D014178:Translocation, Genetic