Fragile-X mutation proposed to block complete reactivation in females of an inactive X chromosome.
I discuss two aspects of my proposal that fra(X) chromosomes exist in two states, imprinted and non-imprinted: why do males not imprint the fra(X); does the "Sherman paradox" rule out my proposal?
Laird
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CD
Department of Zoology, University of Washington, Seattle 98195.
D004303:Dosage Compensation, Genetic; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics*; D006801:Humans; D008297:Male; D008957:Models, Genetic; D009030:Mosaicism; D009154:Mutation; D012729:Sex Chromosome Aberrations / Q000235:genetics*