title: Azidothymidine-induced depression of murine hemopoietic progenitor cells.
abstract: The toxicity of the antiviral drug 3'-azido-3'-deoxythymidine was studied in vivo on murine hemopoietic progenitor cells and peripheral blood cells. The drug induced a marked decrease of all tested populations, showing a severe toxicity on hemopoiesis.
authors.affiliation: Istituto Scientifico di Medicina Interna, University of Genoa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Bogliolo
authors.forename: R
authors.initials: R
authors.lastname: Lerza
authors.forename: M
authors.initials: M
authors.lastname: Mencoboni
authors.forename: A
authors.initials: A
authors.lastname: Saviane
authors.forename: I
authors.initials: I
authors.lastname: Pannacciulli
mesh_terms: D000818:Animals; D001773:Blood Cells / Q000187:drug effects; D001854:Bone Marrow Cells; D005260:Female; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D008297:Male; D051379:Mice; D008811:Mice, Inbred DBA; D015215:Zidovudine / Q000494:pharmacology*
chemical_list: D015215:Zidovudine