title: [Cypermethrin induction of micronuclei in mammalian somatic cells].
abstract: The genotoxic effects of the preparative cypermethrin form on the induction of micronuclei in cultured Chinese hamster V-79 cells and polychromatic erythrocytes of mouse bone marrow have been studied. The cypermethrin has induced micronuclei in cultured cells without metabolic activation in toxic concentrations, similar effects being observed in polychromatic erythrocytes after treatment with subtoxic concentrations.
authors.forename: L M
authors.initials: LM
authors.lastname: Bakhitova
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Pashin
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000648:ultrastructure; D002460:Cell Line; D002478:Cells, Cultured; D006224:Cricetinae; D003412:Cricetulus; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000187:drug effects* / Q000648:ultrastructure; D007306:Insecticides / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D015162:Micronucleus Tests / Q000379:methods*; D011722:Pyrethrins / Q000494:pharmacology* / Q000633:toxicity
chemical_list: D007306:Insecticides; D011722:Pyrethrins; C017160:cypermethrin
vernacular_title: Induktsiia tsipermetrinom mikroiader v somaticheskikh kletkakh mlekopitaiushchikh.