title: [Clinical aspects of Toxoplasma primary infection in pregnancy].
abstract: Prevention of connatal toxoplasmosis is only possible by early diagnosis and treatment of toxoplasma-primoinfection in pregnancy. The authors describe the diagnostic approach and report on 110 pregnant women with toxoplasma-primoinfection. Treatment consisted in the application of pyrimethamine in combination with a sulfonamide or spiramycine. Side-effects of pyrimethamine are mentioned. The aim is an improvement of diagnosis and therapy.
authors.affiliation: Institut für Infektionskrankheiten und Tropenmedizin, Klinikum Berlin-Buch, DDR.
authors.forename: J
authors.initials: J
authors.lastname: Scheibe
authors.forename: K R
authors.initials: KR
authors.lastname: Schulz
authors.forename: H G
authors.initials: HG
authors.lastname: Kupferschmidt
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy*; D011739:Pyrimethamine / Q000009:adverse effects / Q000627:therapeutic use*; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000175:diagnosis / Q000188:drug therapy*; D014125:Toxoplasmosis, Congenital / Q000517:prevention & control*
chemical_list: D000913:Antibodies, Protozoan; D011739:Pyrimethamine
vernacular_title: Klinische Gesichtspunkte der Toxoplasma-Primoinfektion in der Schwangerschaft.