Microwave effect on camphor binding to rat olfactory epithelium.
Microwave radiation decreased specific camphor binding to a membrane fraction of rat epithelium but not to a Triton X-100 extract of this fraction. Inhibition of the ligand binding did not depend on the modulation frequency of the microwave field in the region 1-100 Hz and was not a linear function of specific absorption rate (SAR). The decreased ligand binding was due to a shedding or release of the specific camphor-binding protein from the membrane into solution. It is highly probable that several other membrane proteins may be shed into solution during microwave exposure.
Philippova
T M
TM
Institute of Biological Physics, USSR Academy of Science, Puschino, Moscow Region.
Novoselov
V I
VI
Bystrova
M F
MF
Alekseev
S I
SI
D000818:Animals; D002164:Camphor / Q000378:metabolism*; D005260:Female; D066298:In Vitro Techniques; D008872:Microwaves; D008954:Models, Biological; D009831:Olfactory Mucosa / Q000378:metabolism / Q000528:radiation effects*; D011869:Radioligand Assay; D051381:Rats; D011919:Rats, Inbred Strains
D002164:Camphor