Evaluation of a high-resolution gas chromatography/high-resolution mass spectrometry method for the determination of 2,3,7,8-tetrachlorodibenzo-p-dioxin in soil and water.
An analytical protocol for the determination of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) and total TCDDs in soil, sediment, and aqueous samples using high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS) was evaluated through replicate analyses of fortified and unspiked soil and aqueous samples. The results of these analyses demonstrated that the method is useful for the determination of 2,3,7,8-TCDD and total TCDDs at concentrations ranging from 10 to 200 pg/g (ppt) in soil samples and from 100 to 2000 pg/l (ppq) in aqueous samples. Absolute recoveries of the method internal standard, (13C12-2,3,7,8-TCDD, ranged from 24 to 88%. Lower levels of detection can be achieved through a slight modification of the method with respect to initial sample size and/or final extract volume. Instrumental parameters that affect data quality, specifically HRGC column performance, mass resolution and mass measurement accuracy are presented.
Stanley
J S
JS
Midwest Research Institute, Kansas City, Missouri 64110.
Sack
T M
TM
Tondeur
Y
Y
Beckert
W F
WF
D004147:Dioxins / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D007202:Indicators and Reagents; D000072317:Polychlorinated Dibenzodioxins / Q000032:analysis*; D012989:Soil Pollutants / Q000032:analysis*; D014873:Water Pollutants / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D004147:Dioxins; D007202:Indicators and Reagents; D000072317:Polychlorinated Dibenzodioxins; D012989:Soil Pollutants; D014873:Water Pollutants; D014874:Water Pollutants, Chemical