title: Rhizopus arrhizus in Italy as the causative agent of primary cerebral zygomycosis in a drug addict.
abstract: A rare case of primary cerebral zygomycosis in an Italian drug addict is described. The diagnosis was based on the histologic detection of broad, aseptate, hyaline mycelium in fluid aspirated from a brain mass detected by computerized axial tomography. The zygomycete isolated from the clinical specimen was identified as Rhizopus arrhizus var arrhizus. The patient had no known predisposing condition that would have suppressed his immunological defenses. Once the diagnosis was established, treatment with amphotericin B was initiated, but the patient died during the first day of treatment.
authors.affiliation: Istituto di Microbiologia, Università di Catania, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Oliveri
authors.forename: E
authors.initials: E
authors.lastname: Cammarata
authors.forename: G
authors.initials: G
authors.lastname: Augello
authors.forename: P
authors.initials: P
authors.lastname: Mancuso
authors.forename: R
authors.initials: R
authors.lastname: Tropea
authors.forename: L
authors.initials: L
authors.lastname: Ajello
authors.forename: A A
authors.initials: AA
authors.lastname: Padhye
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001927:Brain Diseases / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007558:Italy; D008297:Male; D009091:Mucormycosis / Q000188:drug therapy / Q000382:microbiology*; D012233:Rhizopus / Q000302:isolation & purification*; D019966:Substance-Related Disorders / Q000150:complications
chemical_list: D000666:Amphotericin B