Stimulation of sea star Asterias rubens axial organ B-like cells by Nocardia-delipidated cell mitogen and derived fractions.
The axial organ (AO-cells) of the starfish Asterias rubens is a primitive immune organ. The total population was fractionated into two populations: adherent (B-like) and non-adherent (T-like) to nylon wool. Nocardia-delipidated cell mitogen (NDCM), Nocardia water soluble mitogen (NWSM), NWSM-pellet (NWSMP) and purified cell walls (CW) from Nocardia opaca induce the proliferation of B-like cells from the axial organ. The Nocardia immunomodulators studied are inactive on the total and T-like population. The mitogenic activity of B-like cells requires the presence of phagocytic cells.
Leclerc
M
M
Département de Biologie, Université d'Orléans, France.
Bahmaoud
T
T
Brillouet
C
C
Tlaskalová-Hogenová
H
H
Petit
J F
JF
Barot-Ciorbaru
R
R
D000818:Animals; D002455:Cell Division; D002470:Cell Survival; D002473:Cell Wall / Q000502:physiology; D002478:Cells, Cultured; D004261:DNA Replication; D008934:Mitogens / Q000494:pharmacology*; D009615:Nocardia; D013215:Starfish / Q000166:cytology / Q000502:physiology*; D013936:Thymidine / Q000378:metabolism
D008934:Mitogens; D013936:Thymidine