Spondyloepiphyseal dysplasia tarda: linkage with genetic markers from the distal short arm of the X chromosome.
A linkage study of six families with spondyloepiphyseal dysplasia tarda (SEDL) has been performed. A linkage to site DXS41 (theta = 0.08; z = 3.07) and DXS92 (theta = 0.05; z = 2.95) has been established. We propose that the SEDL locus lies on the distal part of the short arm of the X chromosome.
Szpiro-Tapia
S
S
Unité de Recherches de Génétique Médicale, INSERM U. 12, Hôpital des Enfants-Malades, Paris, France.
Sefiani
A
A
Guilloud-Bataille
M
M
Heuertz
S
S
Le Marec
B
B
Frézal
J
J
Maroteaux
P
P
Hors-Cayla
M C
MC
D002874:Chromosome Mapping; D015342:DNA Probes; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008297:Male; D010009:Osteochondrodysplasias / Q000235:genetics*; D010375:Pedigree; D014960:X Chromosome
D015342:DNA Probes; D005819:Genetic Markers