Preparation and physicochemical properties of uracil derivatives with potential biological activity.
The characterization of mono- and dimethylated 5-substituted uracils was re-examined. Analysis of their physicochemical properties (pKa, U.V., delta 1H-N.M.R.) affords insight into the structural characteristics of 5-substituted uracil alkylated at the ring nitrogens.
Pecorari
P
P
Dipartimento di Scienze Farmaceutiche, Università di Modena, Italy.
Vampa
G
G
Albasini
A
A
Rinaldi
M
M
Melegari
M
M
Costi
M P
MP
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014498:Uracil / Q000031:analogs & derivatives* / Q000032:analysis
D014498:Uracil