[Morphologic study of the effects of acute stress and the separate administration of "adaptive hormones" on mouse hepatocytes].
Electron microscopy and morphometry methods have been used to study structural changes in mouse hepatocytes under the conditions of acute stress after the injection of adrenaline, glucagon and hydrocortisone. All these factors induce autophagocytosis intensification. It is supposed that the activation of autophagocytosis and autophagocytolysis under these conditions is realized through the intensification of free radicals' generation in hepatocytes.
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D000222:Adaptation, Physiological / Q000187:drug effects*; D000818:Animals; D001343:Autophagy / Q000187:drug effects; D004837:Epinephrine / Q000494:pharmacology*; D005934:Glucagon / Q000494:pharmacology*; D006854:Hydrocortisone / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000648:ultrastructure*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D013312:Stress, Physiological / Q000473:pathology*
D005934:Glucagon; D006854:Hydrocortisone; D004837:Epinephrine
Morfologicheskoe issledovanie éffektov ostrogo stressa i razdel'nogo vvedeniia "adaptivnykh gormonov" na gepatotsity mysheĭ.