title: The effects of morbid obesity and the Garren-Edwards gastric bubble on solid phase gastric emptying.
abstract: Rapid solid phase gastric emptying (SPGE) resulting in decreased satiety is postulated to be a contributing factor to obesity. Twenty-six morbidly obese patients with a weight range of 189-523 lb were entered into the Garren-Edwards gastric bubble program. SPGE studies were performed pre-bubble implantation and repeated within 2 wk after bubble implant. There was no significant difference between study patients pre-bubble insertion emptying time and the normal population curve. Emptying time was found to be significantly increased, post-bubble implant, compared with pre-bubble implant over five time periods of testing. The Garren-Edwards gastric bubble has been used as a method for inducing early satiety for the morbidly obese patient. It has been postulated that delay of SPGE would be associated with satiety. Our patients experienced satiety despite their more rapid SPGE. Thus, the satiety which was experienced by our subjects was not on the basis of delayed SPGE, as previously thought.
authors.affiliation: Division of Gastroenterology, University of Miami, School of Medicine, Florida.
authors.forename: J S
authors.initials: JS
authors.lastname: Barkin
authors.forename: D K
authors.initials: DK
authors.lastname: Reiner
authors.forename: R I
authors.initials: RI
authors.lastname: Goldberg
authors.forename: R S
authors.initials: RS
authors.lastname: Phillips
authors.forename: W R
authors.initials: WR
authors.lastname: Janowitz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000503:physiopathology / Q000628:therapy*; D019736:Prostheses and Implants; D012527:Satiation / Q000502:physiology