Rifampicin induced uterine bleeding.
A case of uterine bleeding after intake of rifampicin is reported in a 35-year-old female. Provocation test was also positive. The underlying mechanism whether it was a hypersensitivity phenomenon like fixed drug eruption or due to induction of uterine acyl-hydrolase enzyme, is not clear. Uterine bleeding has not been observed as a side-effect of rifampicin in the past.
Nigam
P K
PK
Department of Dermatology, Institute of Medical Sciences, B.H.U., Varanasi.
Singh
P K
PK
Singh
G
G
Kumar
M
M
D000328:Adult; D003622:Dapsone / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D015441:Leprosy, Tuberculoid / Q000188:drug therapy; D012293:Rifampin / Q000008:administration & dosage / Q000009:adverse effects*; D014592:Uterine Hemorrhage / Q000139:chemically induced* / Q000473:pathology
D003622:Dapsone; D012293:Rifampin