title: Abnormal gastroduodenal motility in children and adolescents with recurrent functional abdominal pain.
abstract: To determine whether motor activity of the stomach and proximal small intestine is a factor in recurrent abdominal pain in adolescents, we prospectively investigated eight patients with recurrent abdominal pain and compared them with seven normal adolescents. All patients underwent a detailed examination to exclude other known organic causes of the pain. The gastroduodenal motor activity during fasting was studied with a semiconductor recording probe. The recordings were analyzed for periodicity, duration, and propagation velocity of the activity front of the migrating motor complex. The amplitude of the antral and duodenal contractions was also determined. The patients with recurrent abdominal pain had more frequent migrating motor complexes, but these were shorter in duration and moved more slowly down the intestine (slower propagation velocities). The patients also had high-pressure duodenal contractions that were associated with abdominal pain during the study period. These studies suggest that altered intestinal motility may be the underlying mechanism of recurrent abdominal pain in some children.
authors.affiliation: Department of Pediatrics, Wilford Hall United States Air Force Medical Center, Lackland Air Force Base, Texas.
authors.forename: V M
authors.initials: VM
authors.lastname: Piñeiro-Carrero
authors.forename: J M
authors.initials: JM
authors.lastname: Andres
authors.forename: R H
authors.initials: RH
authors.lastname: Davis
authors.forename: J R
authors.initials: JR
authors.lastname: Mathias
mesh_terms: D000005:Abdomen; D000293:Adolescent; D002648:Child; D004386:Duodenum / Q000503:physiopathology; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D008297:Male; D010146:Pain / Q000209:etiology*; D011446:Prospective Studies; D011706:Pyloric Antrum / Q000503:physiopathology; D012008:Recurrence