Ocular alterations induced by hyperproteinic diet in growing rats.
According to literature reports about experimental damages in several organs with high metabolic rate induced by a rich animal protein diet, authors studied in rats, which had been exposed to hyperproteinic diet (casein 40%, lactalbumin 20%) since fetal life, the eyeball and external ocular muscle modifications. Histologic studies at different times have shown that in 60 day old rats a vacuolar degeneration was present in both rod and cone layer and outer nuclear layer of the retina. In 80 day old rats, together with a complete degeneration of the whole retina, external ocular muscles appeared severely fragmentated showing lipid degeneration areas along their bundles.
Bonavolontà
O
O
Istituto di Strutture Biologiche e Ultrastruttura Cellulare, Il Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli.
Ferrante
P
P
Greco
G M
GM
D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D004044:Dietary Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005333:Fetus; D008297:Male; D009801:Oculomotor Muscles / Q000187:drug effects* / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains / Q000254:growth & development; D012160:Retina / Q000187:drug effects* / Q000473:pathology
D004044:Dietary Proteins