title: [Trial of pentamidine in the treatment of trypanosomiasis of sheep inoculated with Trypanosoma brucei brucei].
abstract: An experimental study was carried out using 5 Trypanosoma brucei brucei subcutaneously infected sheep. Pentamidine treatment appeared in the CSF. Two animals were injected daily for 10 days and they died with drug intoxication. Two animals received drug every 3 days for 15 days: one of them died, the other was cured after 3 weeks of set-back. This preliminary study should be completed by experimentation made over a more important period of time.
authors.affiliation: Laboratoire départemental vétérinaire, Limoges.
authors.forename: J A
authors.initials: JA
authors.lastname: Nicolas
authors.forename: C
authors.initials: C
authors.lastname: Bosgiraud
authors.forename: G
authors.initials: G
authors.lastname: Dubost
authors.forename: M
authors.initials: M
authors.lastname: Amevigbe
authors.forename: M
authors.initials: M
authors.lastname: Pestre-Alexandre
authors.forename: B
authors.initials: B
authors.lastname: Bouteille
authors.forename: M L
authors.initials: ML
authors.lastname: Darde
authors.forename: J M
authors.initials: JM
authors.lastname: Vallat
authors.forename: M
authors.initials: M
authors.lastname: Dumas
mesh_terms: D000578:Amidines / Q000627:therapeutic use*; D000818:Animals; D010419:Pentamidine / Q000627:therapeutic use*; D012756:Sheep; D014346:Trypanosoma brucei brucei; D014353:Trypanosomiasis, African / Q000188:drug therapy*
chemical_list: D000578:Amidines; D010419:Pentamidine
vernacular_title: Essai de la pentamidine dans le traitement de la trypanosomiase du mouton inoculé par Trypanosoma brucei brucei.