title: Material thrombelastography: an assessment of phosphorylcholine compounds as models for biomaterials.
abstract: The use of phosphorylcholine (PC) containing compounds as possible biomaterials has been evaluated by material thrombelastography (MTEG). The detailed analysis of the MTEG technique is discussed. A remarkable reduction of thrombogenicity by compounds containing the PC group is demonstrated. The results observed with a polymerised PC-lipid indicate potential use of such substances as biomaterials with minimal thrombogenicity.
authors.affiliation: Academic Department of Surgery, Royal Free Hospital School of Medicine, University of London, United Kingdom.
authors.forename: R R
authors.initials: RR
authors.lastname: Bird
authors.forename: B
authors.initials: B
authors.lastname: Hall
authors.forename: D
authors.initials: D
authors.lastname: Chapman
authors.forename: K E
authors.initials: KE
authors.lastname: Hobbs
mesh_terms: D015060:1,2-Dipalmitoylphosphatidylcholine / Q000494:pharmacology; D001672:Biocompatible Materials; D006801:Humans; D066298:In Vitro Techniques; D008422:Materials Testing / Q000379:methods*; D010713:Phosphatidylcholines / Q000494:pharmacology; D013916:Thrombelastography; D013927:Thrombosis / Q000517:prevention & control
chemical_list: D001672:Biocompatible Materials; D010713:Phosphatidylcholines; C044819:1,2-diarachidonoyl-glycero-3-phosphocholine; D015060:1,2-Dipalmitoylphosphatidylcholine