Perfluoroctylbromide and hepatosplenic computed tomography. Preliminary clinical study.
The preliminary results of perfluorocytlbromide (PFOB) emulsion when used as an intravenous contrast agent for hepatosplenic CT imaging in humans are reported. Ten patients were examined using dosages ranging from 1 to 2 g/kg. There was good clinical and biochemical tolerance. Diagnostic dose for liver enhancement seems to be at least 2 g/kg, whereas 1 g/kg was sufficient for splenic enhancement.
Bruneton
J N
JN
Department of Radiology, Centre Antoine, Lacassagne, Nice, France.
Falewee
M N
MN
Balu-Maestro
C
C
Normand
F
F
Mattrey
R F
RF
D003287:Contrast Media; D005466:Fluorocarbons; D006801:Humans; D006842:Hydrocarbons, Brominated; D008099:Liver / Q000000981:diagnostic imaging*; D013154:Spleen / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
D003287:Contrast Media; D005466:Fluorocarbons; D006842:Hydrocarbons, Brominated; C003072:perflubron