Properdin factor B(Bf) polymorphism in the population of Veneto, Italy.
The distribution of Bf phenotypes in the population of Veneto was investigated by agarose gel electrophoresis and immunofixation. In our sample (n = 592), the seven common phenotypes F, S, F-S, S-S0.7, S-F1, F-S0.7, F-F1 were observed and the following gene frequencies calculated: Bf*S = 0.7399; Bf*F = 0.2280; Bf*F1 = 0.0177; Bf*S0.7 = 0.0144. These gene frequencies are compared to those found in other populations. Analysis of 21 mother-child pairs was in agreement with an autosomal codominant inheritance.
Crestani
C
C
Istituto di Medicina Legale dell'Universita, Padova, Italy.
Caenazzo
L
L
Cortivo
P
P
Scorretti
C
C
Caenazzo
C
C
D011415:Complement Factor B / Q000235:genetics*; D004792:Enzyme Precursors / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D007558:Italy; D010641:Phenotype; D011110:Polymorphism, Genetic
D004792:Enzyme Precursors; D011415:Complement Factor B