[The effect of thyroid hormones on structural-functional relations in rat liver chromatin].
The effects of thyroid hormones on chromatin structure at different levels of its functional activity were investigated. No differences in the sensitivity of hepatocyte nuclei to DNAase I were found, presumably due to the restriction of acceptor sites for thyroid hormones on DNA.
Adylova
A T
AT
Umarova
G D
GD
Atakhanova
B A
BA
D000818:Animals; D002843:Chromatin / Q000032:analysis* / Q000187:drug effects; D004247:DNA / Q000032:analysis* / Q000187:drug effects; D003850:Deoxyribonuclease I; D006868:Hydrolysis; D008099:Liver / Q000032:analysis* / Q000201:enzymology; D008297:Male; D009690:Nucleic Acid Conformation; D012318:RNA Polymerase I / Q000378:metabolism; D012319:RNA Polymerase II / Q000378:metabolism; D051381:Rats; D013965:Thyroidectomy; D014284:Triiodothyronine / Q000494:pharmacology*
D002843:Chromatin; D014284:Triiodothyronine; D004247:DNA; D012319:RNA Polymerase II; D012318:RNA Polymerase I; D003850:Deoxyribonuclease I
Vliianie tireoidnykh gormonov na strukturno-funktsional'nye vzaimootnosheniia v khromatine pecheni krys.