Are 'homeopathic' doses of oral corticosteroids effective in rheumatoid arthritis?
When patients with rheumatoid arthritis whose clinical disease activity was stable had their oral prednisolone of less than 5 mg per day (mean 3.5 mg) replaced by placebo, there was an almost immediate flare in their arthritis. This confirms that such low dose prednisolone therapy is effective in controlling joint inflammation.
Buchanan
W W
WW
McMaster University Health Sciences Center, Hamilton, Ontario, Canada.
Stephen
L J
LJ
Buchanan
H M
HM
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011239:Prednisolone / Q000008:administration & dosage*
D011239:Prednisolone