[Basic studies on an immunoradiometric assay system for human parathyrin (intact PTH1-84)].
Two-site immunoradiometric assay for human parathyrin (PTH1-84) is specific for the intact, secreted, biologically active 84 amino peptide. This system incorporates two-different polyclonal antibodies to human intact PTH and has several technical advantages for use. This assay could detect a wide range of PTH in patients with hypo-, hyperparathyroidism, chronic renal failure and hypercalcemia with malignancy, especially distinguishing the level of human intact PTH in hypoparathyroidism from in normal.
Kanao
K
K
Department of Nuclear Medicine, Sumitomo Hospital, Osaka-shi, Japan.
Honda
M
M
Ishihara
S
S
Moriuma
H
H
Mishima
T
T
Tomonobu
M
M
Usami
N
N
Kishino
B
B
Itatani
H
H
Morii
H
H
D006801:Humans; D006934:Hypercalcemia / Q000097:blood; D006961:Hyperparathyroidism / Q000097:blood; D007011:Hypoparathyroidism / Q000097:blood; D007676:Kidney Failure, Chronic / Q000097:blood; D010190:Pancreatic Neoplasms / Q000097:blood; D010281:Parathyroid Hormone / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods*
D010281:Parathyroid Hormone