title: The negative association between a history of recurrent herpes labialis and cervical neoplasia.
abstract: We considered the possibility that herpetic recurrences and herpes virus associated neoplasia are mutually exclusive disorders because they are expressions of different herpes virus-host relationships. We assumed that the human body copes with orofacial and genital herpes infections in the same manner. In our retrospective study, the relative risk of a history of fever blisters for cervical neoplasia was estimated to be 0.49, with 0.34 and 0.69 as the limits of the 95% confidence interval. It is suggested that recurrent herpes labialis is presumably a determinant of an effective immune response in general.
authors.affiliation: Department of Obstetrics and Gynecology, University Hospital, Groningen, The Netherlands.
authors.forename: M P
authors.initials: MP
authors.lastname: Burger
authors.forename: J B
authors.initials: JB
authors.lastname: Wilterdink
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006560:Herpes Labialis / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000209:etiology*