Drug-induced catatonia.
An 81 year old depressed female is described who developed catatonic-like behaviours while on the combination of the monoamine oxidase inhibitor phenelzine, and the neuroleptic haloperidol. Alternative etiologies, and the roles of the individual agents are discussed. It is suggested that whenever there is evidence of drug-induced catatonia, consideration should be given to stopping all medications.
Herrmann
N
N
Baycrest Hospital, Department of Psychiatry, Toronto, Ontario.
Lieff
S J
SJ
D000368:Aged; D000369:Aged, 80 and over; D002389:Catatonia / Q000139:chemically induced*; D003704:Dementia / Q000188:drug therapy*; D003866:Depressive Disorder / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006220:Haloperidol / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D010624:Phenelzine / Q000009:adverse effects* / Q000627:therapeutic use
D006220:Haloperidol; D010624:Phenelzine