Fluorescent granular perithelial cells in the meninges and optic nerve of the human embryo.
Cells containing small dense granules were present in the meninges surrounding the human embryonic optic nerve from 8 weeks post-conception. Typical fluorescent granular perithelial cells (FGP) containing large dense granules were present in the meninges by 12 weeks post-conception and in the large perivascular space around large vessels within the optic nerve by 14-15 weeks post-conception. The time of appearance of these cells in the CNS seems to be related to the stage of vascularization rather than to the stage of CNS development.
Sturrock
R R
RR
Department of Anatomy, University of Dundee, Scotland.
D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006801:Humans; D008578:Meninges / Q000196:embryology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009900:Optic Nerve / Q000196:embryology* / Q000648:ultrastructure