title: Protogonyaulax cohorticula, a toxic dinoflagellate found in the Gulf of Thailand.
abstract: Two clones of Protogonyaulax cohorticula were isolated from the Gulf of Thailand. The extracts of these clones killed mice with typical signs of paralytic shellfish poisoning. The toxicities corresponded to those of strongly toxic clones of P. tamarensis. In the HPLC and electrophoretic analyses, gonyautoxins and saxitoxin were detected. About 80% of the toxins consisted of gonyautoxin I. These results show that P. cohorticula is a toxic species of Protogonyaulax and that it is at least one of the causative organisms of paralytic shellfish poisoning in Thailand.
authors.affiliation: Laboratory of Marine Biological Chemistry, School of Fisheries Sciences, Kitasato University, Iwate, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kodama
authors.forename: T
authors.initials: T
authors.lastname: Ogata
authors.forename: Y
authors.initials: Y
authors.lastname: Fukuyo
authors.forename: T
authors.initials: T
authors.lastname: Ishimaru
authors.forename: S
authors.initials: S
authors.lastname: Wisessang
authors.forename: K
authors.initials: K
authors.lastname: Saitanu
authors.forename: V
authors.initials: V
authors.lastname: Panichyakarn
authors.forename: T
authors.initials: T
authors.lastname: Piyakarnchana
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004141:Dinoflagellida; D008387:Marine Toxins / Q000302:isolation & purification*; D051379:Mice; D010243:Paralysis / Q000139:chemically induced; D012758:Shellfish / Q000009:adverse effects; D013785:Thailand
chemical_list: D008387:Marine Toxins