A case of death from prothiophos poisoning.
A 62-year-old male, a farmer, who had ingested prothiophos (Tokuthion), died after 21 h of intensive care. Prothiophos in the tissues of the victim was extracted and purified by Extrelut column extraction. A gas chromatograph equipped with a flame photometric detector, and a gas chromatograph-mass spectrometer were used to detect prothiophos. The concentration of prothiophos was 10.9 micrograms/g in the brain, 8.6 micrograms/g in the kidney, 418 micrograms/g in the liver, 2.96 mg/g in the gastric contents and 4.69 mg/g in the intestinal contents. The case history and the distribution of prothiophos indicated that the cause of death was acute prothiophos poisoning.
Miyazaki
T
T
Department of Legal Medicine, Hiroshima University School of Medicine, Japan.
Yashiki
M
M
Chikasue
F
F
Kojima
T
T
Hibino
H
H
D001923:Brain Chemistry; D003128:Coma / Q000209:etiology; D008401:Gas Chromatography-Mass Spectrometry; D005766:Gastrointestinal Contents / Q000032:analysis; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008297:Male; D008875:Middle Aged; D062025:Organophosphate Poisoning; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds / Q000506:poisoning*
D007306:Insecticides; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds; C032072:prothiophos