title: [Determination of clearance for urea-controlled hemodialysis].
abstract: Through a simple variant of the urea model the qualitative influence of the dialyzer-clearance on the individual dialysis guidance is elucidated. Realization of the respective Kdtd/V-value require an exact knowledge of the in-vivo-urea-clearance of all available dialyzer types and their manipulation with the aid of blood flow. The theoretical connections are explained and possible parameters affecting the in-vivo-clearance are discussed. The results concerning the dependence of urea-clearance on the blood flow are presented in an urea-guided dialysis patient pool for all in the GDR customary in the trade or temporary available dialyzers. It is shown, that in MLW-dialyzers an influence on the urea-clearance about the blood flow is small because of their relatively thick-walled membrane. Therefore, the development of dialysis membranes with superior diffusible permeability is necessary.
authors.affiliation: Klinik für Innere Medizin, Bereiches Medizin der Wilhelm-Pieck-Universität Rostock.
authors.forename: P
authors.initials: P
authors.lastname: Ahrenholz
authors.forename: M
authors.initials: M
authors.lastname: Holtz
authors.forename: D
authors.initials: D
authors.lastname: Falkenhagen
authors.forename: H
authors.initials: H
authors.lastname: Klinkmann
mesh_terms: D001783:Blood Flow Velocity; D001806:Blood Urea Nitrogen; D005919:Glomerular Filtration Rate; D006801:Humans; D007688:Kidneys, Artificial; D008567:Membranes, Artificial; D006435:Renal Dialysis / Q000379:methods*
chemical_list: D008567:Membranes, Artificial
vernacular_title: Clearancebestimmungen für die harnstoffgeführte Hämodialyse.