title: Interactions of streptococci with human colostral immunoglobulin A.
abstract: Streptococci of serological groups A, B, C, G and L were examined for interactions with human colostral IgA. Of 28 A-streptococcal cultures, 12 bound IgA with a mean of 38.7%. The other streptococci had little or no IgA-binding activities. Of the 12 IgA-binding A-streptococcal cultures, 8 contained the M-protein M 4 and 2 the M-protein M 60. The specific binding sites for IgA were heat-sensitive (60 min, 80 degrees C) and susceptible to trypsin and pronase.
authors.affiliation: Institut für Bakteriologie und Immunologie der Justus-Liebig-Universität Giessen, F.R.G.
authors.forename: C
authors.initials: C
authors.lastname: Lämmler
authors.forename: C
authors.initials: C
authors.lastname: Frede
authors.forename: H
authors.initials: H
authors.lastname: Blobel
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D002417:Cattle; D003126:Colostrum / Q000276:immunology*; D004285:Dogs; D006736:Horses; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000276:immunology*; D013291:Streptococcus / Q000276:immunology*
chemical_list: D007071:Immunoglobulin A, Secretory