[Annual rhythm of the excretion of indole melanogen in human urine].
Comparing the monthly indole melanogen mean values (4,100 single values within 5 years) in patients with malignant melanomas showing a normal urinary indole melanogen concentration we have found a seasonal effect with a maximum melanogen excretion in spring (March) and summer (July) and a minimum in autumn (September). These results are statistically significant. The possible importance of these seasonal influences for the prognosis in individual cases of malignant melanoma is discussed.
Schwartze
G
G
Klinik und Poliklinik für Hautkrankheiten der Bereiches Medizin, Martin-Luther-Universität Halle, Wittenberg.
D006801:Humans; D007211:Indoles / Q000652:urine*; D008545:Melanoma / Q000652:urine*; D010507:Periodicity
D007211:Indoles; C009904:melanogen
Jahresrhythmik der Ausscheidung von Indolmelanogenen im menschlichen Harn.