[Hexamidine content of the blood plasma and cerebrospinal fluid in patients with epilepsy].
In 74 patients with different attack rates and patterns mean levels of hexamidine in the blood plasma and cerebrospinal fluid were 15.9 micrograms/ml and 7.86 micrograms/ml, respectively, the former almost twice as high as the latter. Both were found to correlate with the drug daily doses and other anticonvulsants administration.
Gromov
S A
SA
Fedotenkova
T N
TN
Stabrovskiĭ
E M
EM
D000293:Adolescent; D000328:Adult; D001550:Benzamidines / Q000097:blood / Q000134:cerebrospinal fluid / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004827:Epilepsy / Q000188:drug therapy / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011324:Primidone / Q000032:analysis* / Q000493:pharmacokinetics / Q000627:therapeutic use; D011863:Radioimmunoassay; D013997:Time Factors
D001550:Benzamidines; D011324:Primidone; C018961:hexamidine
O soderzhanii geksamidina v plazme krovi i likvore u bol'nykh épilepsieĭ.