title: Neurologic, endocrinologic, and pathologic findings associated with large pituitary tumors in dogs: eight cases (1976-1984).
abstract: Invasive tumors of the pituitary gland were diagnosed in 8 dogs. Seven of the dogs had been treated for pituitary-dependent hyperadrenocorticism before the onset of neurologic signs. All 8 dogs had behavior abnormalities and similar neurologic signs: 6 dogs had rotary nystagmus and 7 dogs had symmetric tetraparesis. Once neurologic signs developed, the clinical course in all 8 dogs had a mean duration of 4.7 +/- 2.0 months before death or euthanasia; 5 dogs had a clinical course of less than or equal to 2 months. Necropsy was performed in 7 dogs. The histologic diagnosis was malignant pituitary adenocarcinoma in 2 dogs and pituitary adenoma in 5 dogs.
authors.affiliation: Department of Medicine, Animal Medical Center, New York, NY 10021.
authors.forename: D
authors.initials: D
authors.lastname: Sarfaty
authors.forename: J M
authors.initials: JM
authors.lastname: Carrillo
authors.forename: M E
authors.initials: ME
authors.lastname: Peterson
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D000308:Adrenocortical Hyperfunction / Q000209:etiology / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000473:pathology / Q000503:physiopathology*; D004285:Dogs; D005260:Female; D008297:Male; D009460:Neurologic Examination / Q000662:veterinary; D010911:Pituitary Neoplasms / Q000150:complications / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D012189:Retrospective Studies