title: Serum amphotericin-B assay by scanning spectrophotometer.
abstract: We describe a simple, specific, 3-min assay for amphotericin-B in serum based on the absorbance at 408 nm and spectral scanning between 450 and 350 nm of the drug in acetonitrile extracts. The method correlated well with a high-performance liquid chromatographic method.
authors.affiliation: Department of Pathology, Wake Forest University, Bowman Gray School of Medicine, Winston-Salem, North Carolina.
authors.forename: Z K
authors.initials: ZK
authors.lastname: Shihabi
authors.forename: B L
authors.initials: BL
authors.lastname: Wasilauskas
authors.forename: J E
authors.initials: JE
authors.lastname: Peacock
mesh_terms: D000666:Amphotericin B / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D013053:Spectrophotometry
chemical_list: D000666:Amphotericin B