Anterior neocortical kindling in vasopressin-deficient rats.
Kindling of seizures with stimulation of anterior neocortex was examined in control rats and in Brattleboro rats deficient in arginine-vasopressin (AVP). There were no significant differences between control rats, homozygous Brattleboro rats, and heterozygous Brattleboro rats in the rate and pattern of kindling of generalized seizures. Thus AVP is not critically involved in anterior neocortical kindling.
Weller
K L
KL
Department of Psychology, University of Victoria, B.C., Canada.
Corcoran
M E
ME
D000818:Animals; D001127:Arginine Vasopressin / Q000378:metabolism / Q000502:physiology*; D002540:Cerebral Cortex / Q000378:metabolism / Q000503:physiopathology*; D004558:Electric Stimulation; D007696:Kindling, Neurologic; D008297:Male; D051381:Rats; D011910:Rats, Brattleboro / Q000378:metabolism / Q000502:physiology*; D011922:Rats, Mutant Strains / Q000502:physiology*
D001127:Arginine Vasopressin