[Effect of magnesium sulfate on the reproduction of the measles virus in cell culture].
Magnesium sulphate in concentrations of 25-50 mM induced reproducible increase in titers of extracellular measles virus (by 0.5-2.0 1g TCD50/0.5 ml) in Japanese quail embryo cells. MgSO4 effect was observed with all methods of cell cultivation: stationary, roller, or on microcarriers. Its effect was associated not with its stabilizing influence on the extracellular virus but rather with the stimulation of the synthesis of intracellular viral proteins.
Shteĭnberg
L Sh
LSh
Dorofeeva
L V
LV
Zasorina
I N
IN
Barkova
E P
EP
Boriskin
Iu S
IuS
D000818:Animals; D003370:Coturnix; D003588:Cytopathogenic Effect, Viral; D004305:Dose-Response Relationship, Drug; D008278:Magnesium Sulfate / Q000494:pharmacology*; D008459:Measles virus / Q000187:drug effects* / Q000472:pathogenicity / Q000502:physiology; D013997:Time Factors; D014709:Vero Cells; D014776:Virus Cultivation / Q000379:methods; D014779:Virus Replication / Q000187:drug effects*
D008278:Magnesium Sulfate
Vliianie sul'fata magniia na reproduktsiiu virusa kori v kul'ture kletok.