Inactivation of Giardia lamblia and Giardia canis cysts by combined and free chlorine.
Free chlorine and a combined organic N-chloramine (3-chloro-4,4-dimethyl-2-oxazolidinone, compound 1) were compared for efficacy as disinfectants against an admixture of cysts of Giardia lamblia and Giardia canis in water solution under a variety of test conditions; variables were pH, temperature, and water quality. In general, compound 1 was found to reduce the giardial excystation in the solutions at lower concentration or shorter contact time at a given total chlorine concentration than did free chlorine.
Kong
L I
LI
Department of Pathobiology, College of Veterinary Medicine, Auburn University, Alabama 36849-5312.
Swango
L J
LJ
Blagburn
B L
BL
Hendrix
C M
CM
Williams
D E
DE
Worley
S D
SD
D000704:Analysis of Variance; D000818:Animals; D002713:Chlorine / Q000494:pharmacology*; D004202:Disinfectants / Q000494:pharmacology*; D005872:Giardia / Q000187:drug effects*; D006863:Hydrogen-Ion Concentration; D010080:Oxazoles / Q000494:pharmacology*; D023303:Oxazolidinones; D013696:Temperature; D014867:Water
D004202:Disinfectants; D010080:Oxazoles; D023303:Oxazolidinones; D014867:Water; D002713:Chlorine; C036350:3-chloro-4,4-dimethyl-2-oxazolidinone