"Placental polyp": light microscopic and immunohistochemical observations.
A case of the chronic type of placental polyp, occurring in a 37-year-old woman approximately 9 years after abortion of her last known pregnancy, is reported. The placental polyp was predominantly composed of necrotic and hyalinized chorionic villi without identifiable lining trophoblast; however, some villi showed a thin rim of apparently viable syncytiotrophoblast that exhibited focal strong positivity for human chorionic gonadotropin by immunohistochemical studies. Intermediate trophoblast, especially abundant within the intervillous fibrin, appeared most viable and showed strong positivity for human placental lactogen (hPL); syncytiotrophoblast also showed focal positivity for hPL. The basal aspect of the polyp was composed of abundant decidua that contained dilated and ectatic blood vessels. This study demonstrates the presence of cytoplasmic markers for pregnancy in a chronic type of placental polyp, apparently of 9 years' duration, and draws attention to an entity that may be encountered more frequently due to the current prevalence of induced abortions.
Lawrence
W D
WD
Department of Pathology, Hutzel Hospital, Detroit, MI 48201.
Qureshi
F
F
Bonakdar
M I
MI
D000328:Adult; D006063:Chorionic Gonadotropin / Q000032:analysis; D005260:Female; D006801:Humans; D010922:Placenta Diseases / Q000378:metabolism / Q000473:pathology*; D011127:Polyps / Q000032:analysis / Q000473:pathology*; D011247:Pregnancy
D006063:Chorionic Gonadotropin