Evaluation of Duraflo II heparin coating in prolonged extracorporeal membrane oxygenation.
Adult sized extracorporeal membrane oxygenation circuits were coated with Duraflo II chemical heparin bonding by Baxter-Bentley Laboratories. Five sheep were maintained on venovenous extracorporeal circulation for four days with no systemic anticoagulation. There was no bleeding, no major thrombosis in the circuits, and no significant emboli after 4 days of extracorporeal circulation without anti-coagulation.
Toomasian
J M
JM
Department of Surgery, University of Michigan, Ann Arbor 48109-0331.
Hsu
L C
LC
Hirschl
R B
RB
Heiss
K F
KF
Hultquist
K A
KA
Bartlett
R H
RH
D000818:Animals; D001777:Blood Coagulation; D005069:Evaluation Studies as Topic; D015199:Extracorporeal Membrane Oxygenation; D006493:Heparin / Q000494:pharmacology*; D007958:Leukocyte Count; D010976:Platelet Count; D012756:Sheep; D014914:Whole Blood Coagulation Time
D006493:Heparin