[Furosemide depression of the dorsal root potentials and of the presynaptic inhibition of monosynaptic reflexes in the cat spinal cord].
In experiments on spinal narcotized cats perfusion of the lumbosacral cord through the central canal with artificial cerebrospinal fluid containing furosemide (15-48 mmol/l) led to the reversible selective depression of negative DRP and to the depression of prolonged "presynaptic" inhibition of extensor monosynaptic reflexes produced by volleys in flexor muscle afferents of group 1.
Ruchinskaia
T Iu
TIu
Sverdlov
Iu S
IuS
D000818:Animals; D002415:Cats; D003864:Depression, Chemical; D005665:Furosemide / Q000494:pharmacology*; D005727:Ganglia, Spinal / Q000187:drug effects* / Q000502:physiology; D008564:Membrane Potentials / Q000187:drug effects; D009433:Neural Inhibition / Q000187:drug effects*; D012023:Reflex, Monosynaptic / Q000187:drug effects*; D013116:Spinal Cord / Q000187:drug effects* / Q000502:physiology; D013569:Synapses / Q000187:drug effects* / Q000502:physiology
D005665:Furosemide
Ugnetenie furosemidom potentsialov dorsal'nykh koreshkov i presinapticheskogo tormozheniia monosinapticheskikh refleksov v spinnom mozge koshki.