title: A knowledge-based system for cassette mutagenesis experimental design.
abstract: A knowledge-based system for the design and planning of cassette mutagenesis experiments has been developed for scientists working in the field of structural biology and protein engineering. The system applies domain-specific knowledge to manage the menial details and automate most of the decision-making steps involved in the design process. This allows scientists to work at a high abstraction level, and results in significant time savings and increased productivity. The system also includes an automated documentation facility to improve the efficiency and accuracy of record keeping.
authors.affiliation: Department of Biomedical Engineering, Vanderbilt University, Nashville, TN.
authors.forename: J
authors.initials: J
authors.lastname: Zheng
authors.forename: K
authors.initials: K
authors.lastname: Jiang
authors.forename: D M
authors.initials: DM
authors.lastname: Watterson
authors.forename: T A
authors.initials: TA
authors.lastname: Craig
authors.forename: S B
authors.initials: SB
authors.lastname: Higgins
mesh_terms: D001185:Artificial Intelligence; D001483:Base Sequence; D003062:Codon; D004252:DNA Mutational Analysis; D005822:Genetic Vectors; D012107:Research Design; D012984:Software; D014584:User-Computer Interface
chemical_list: D003062:Codon