Circumscribed lytic lesions of the thalassaemic skull.
Solitary or multiple circumscribed osteolytic areas are described in seven patients, selected from 250 patients with homozygous beta-thalassaemia (Cooley's anaemia). On X-ray examinations, these areas appear as purely osteolytic lesions with well-defined margins not associated with sclerosis. The possible mechanisms are discussed.
Orzincolo
C
C
Department of Radiology, St. Anna Hospital, Ferrara, Italy.
Castaldi
G
G
Bariani
L
L
Franceschini
F
F
Corcione
S
S
Scutellari
P N
PN
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010014:Osteolysis / Q000000981:diagnostic imaging* / Q000209:etiology; D011859:Radiography; D012886:Skull / Q000000981:diagnostic imaging*; D013789:Thalassemia / Q000150:complications / Q000000981:diagnostic imaging*