[Structural-functional characteristics of the surface of the blood mononucleocytes in children suffering from chronic dermatoses. I. The correction of the glycocalyx structure by UV irradiation of the blood and in the course of treatment with an autotransfusion of UV-irradiated blood].
In children suffering from chronic dermatoses (psoriasis and neurodermatitis), the glycocalix of blood mononuclears displays an Alcian blue dye sorption by 23-25% less than that in healthy children. The UV irradiation of their blood (254 nm), in addition to a course of UV-irradiated blood autotransfusion, resulted in an elevated sorption capacity of the mononuclear glycocalix up to the normal. A possible involvement of these changes in immunocompetent cell glycocalix in the pathogenesis of chronic dermatoses is discussed, as well as the significance of glycocalix normalization in the medicinal effect of UV-irradiated blood autotransfusion.
Finkel'shteĭn
B B
BB
Samoĭlova
K A
KA
Zver'kova
F A
FA
Obolenskaia
K D
KD
D000042:Absorption; D000293:Adolescent; D000423:Alcian Blue; D001804:Blood Transfusion, Autologous / Q000379:methods*; D002648:Child; D002908:Chronic Disease; D003131:Combined Modality Therapy; D006023:Glycoproteins / Q000097:blood / Q000528:radiation effects*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000378:metabolism / Q000528:radiation effects*; D009450:Neurodermatitis / Q000097:blood / Q000628:therapy; D011134:Polysaccharides / Q000097:blood / Q000528:radiation effects*; D011565:Psoriasis / Q000097:blood / Q000628:therapy; D012871:Skin Diseases / Q000097:blood* / Q000628:therapy; D013499:Surface Properties; D014467:Ultraviolet Therapy
D006023:Glycoproteins; D011134:Polysaccharides; D000423:Alcian Blue
Strukturno-funktsional'nye osobennsoti poverkhnosti mononuklearov krovi deteĭ, stradaiushchikh khronicheskimi dermatozami. I. Korrektsiia struktury glikokaliksa pri UF-obluchenii krovi i v kurse lecheniia autotransfuzieĭ UF-obluchennoĭ krovi.