title: [Morphological characteristics of hyperuricemic variant of chronic latent glomerulonephritis].
abstract: The study of a hyperuricemic variant of chronic latent glomerulonephritis in asymptomatic hyperuricemia and gout suggested that relevant pathologic lesion can be morphologically represented by immune-complex glomerulonephritis and reactive mesangial changes as well as secondary tubulointerstitial nephritis. The underlying pathogenetic mechanism in the development of immune-complex glomerulonephritis and secondary tubulointerstitial nephritis is formation of antibodies to antigens of basal glomerular membrane and to alkaline edge of the proximal nephron, respectively. Reactive mesangial changes of the glomeruli reflect mesangiocyte sensitization to the antigens.
authors.forename: M A
authors.initials: MA
authors.lastname: Pal'tsev
authors.forename: V A
authors.initials: VA
authors.lastname: Varshavskii
authors.forename: N A
authors.initials: NA
authors.lastname: Maksimov
authors.forename: I M
authors.initials: IM
authors.lastname: Balkarov
mesh_terms: D000328:Adult; D000917:Antibody Formation; D002908:Chronic Disease; D005260:Female; D005921:Glomerulonephritis / Q000097:blood / Q000276:immunology / Q000473:pathology*; D015432:Glomerulonephritis, Membranoproliferative / Q000473:pathology; D006801:Humans; D008297:Male; D014527:Uric Acid / Q000097:blood*
chemical_list: D014527:Uric Acid
vernacular_title: Morfologicheskaia kharakteristika giperurikemicheskogo varianta khronicheskogo latentnogo glomerulonefrita.