Cryptococcal meningoencephalitis with parkinsonian features.
The subacute onset of parkinsonism in a patient with cryptococcal meningoencephalitis is described. The prompt resolution of the extrapyramidal dysfunction with antifungal agents suggests direct involvement of basal ganglia structures by the cryptococcal infection. Rapid development of parkinsonism in immunocompromised individuals should prompt investigation for an infectious etiology.
Wszolek
Z
Z
Department of Medicine, University of Nebraska Medical Center, Omaha 68105.
Monsour
H
H
Smith
P
P
Pfeiffer
R
R
D000368:Aged; D000369:Aged, 80 and over; D000666:Amphotericin B / Q000627:therapeutic use; D001480:Basal Ganglia Diseases / Q000209:etiology*; D003453:Cryptococcosis / Q000150:complications* / Q000188:drug therapy; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000150:complications* / Q000188:drug therapy; D010300:Parkinson Disease / Q000209:etiology*
D000666:Amphotericin B; D005437:Flucytosine