title: Effect of nitroxazepine on bone marrow cells of mice.
abstract: The antidepressant drug, nitroxazepine, was tested in mice for mutagenicity in bone marrow cells by a micronucleus test. The drug was administered orally at a dose of 4.5, 9, and 13.5 mg per mouse. The results show that the drug is found to be mutagenic in mouse bone marrow cells.
authors.affiliation: Department of Genetics, Osmania University, Hyderabad, India.
authors.forename: S
authors.initials: S
authors.lastname: Shaheen
authors.forename: K P
authors.initials: KP
authors.lastname: Rao
authors.forename: M S
authors.initials: MS
authors.lastname: Rao
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000929:Antidepressive Agents, Tricyclic / Q000633:toxicity*; D001853:Bone Marrow / Q000187:drug effects*; D003989:Dibenzoxazepines / Q000633:toxicity*; D004912:Erythrocytes / Q000187:drug effects; D051379:Mice; D015162:Micronucleus Tests; D009153:Mutagens
chemical_list: D000929:Antidepressive Agents, Tricyclic; D003989:Dibenzoxazepines; D009153:Mutagens; C100140:sintamil