title: [Basic studies on an immunoradiometric assay system for human parathyrin (intact PTH1-84)].
abstract: Two-site immunoradiometric assay for human parathyrin (PTH1-84) is specific for the intact, secreted, biologically active 84 amino peptide. This system incorporates two-different polyclonal antibodies to human intact PTH and has several technical advantages for use. This assay could detect a wide range of PTH in patients with hypo-, hyperparathyroidism, chronic renal failure and hypercalcemia with malignancy, especially distinguishing the level of human intact PTH in hypoparathyroidism from in normal.
authors.affiliation: Department of Nuclear Medicine, Sumitomo Hospital, Osaka-shi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kanao
authors.forename: M
authors.initials: M
authors.lastname: Honda
authors.forename: S
authors.initials: S
authors.lastname: Ishihara
authors.forename: H
authors.initials: H
authors.lastname: Moriuma
authors.forename: T
authors.initials: T
authors.lastname: Mishima
authors.forename: M
authors.initials: M
authors.lastname: Tomonobu
authors.forename: N
authors.initials: N
authors.lastname: Usami
authors.forename: B
authors.initials: B
authors.lastname: Kishino
authors.forename: H
authors.initials: H
authors.lastname: Itatani
authors.forename: H
authors.initials: H
authors.lastname: Morii
mesh_terms: D006801:Humans; D006934:Hypercalcemia / Q000097:blood; D006961:Hyperparathyroidism / Q000097:blood; D007011:Hypoparathyroidism / Q000097:blood; D007676:Kidney Failure, Chronic / Q000097:blood; D010190:Pancreatic Neoplasms / Q000097:blood; D010281:Parathyroid Hormone / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods*
chemical_list: D010281:Parathyroid Hormone