A dermatoglyphic study of a group of Sicilian children with fragile-X syndrome.
In a dermatoglyphic study of 14 fra(X) boys (compared with a control group of 191 normal schoolboys), we observed the following statistically significant (p less than 0.01) differences: 1) lower frequency of ulnar loops on the fingertips, particularly on the 2nd and 3rd fingers, with a corresponding increase of whorls; 2) transverse course of main line A; 3) increased frequency of abnormal palmar creases. The log score index of Simpson et al [1984] identified 71.4% of our patients and that of Rodewald et al [1986] 64.2%. The different values of these indexes can probably be attributed to ethnic differences. We think that by combining the results of dermatoglyphic analysis from several centers a more discriminatory log score index can be obtained.
Milone
G
G
Paediatric Clinic, University of Catania, Italy.
Conti
L
L
Rizzo
R
R
Sanfilippo
S
S
Sammito
V
V
Romano
C
C
D002648:Child; D003878:Dermatoglyphics; D005600:Fragile X Syndrome / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D012729:Sex Chromosome Aberrations / Q000175:diagnosis*