title: Aortic and mitral valve replacement in idiopathic hypereosinophilic syndrome.
abstract: Idiopathic hypereosinophilic syndrome is a rare systemic manifestation of eosinophilia that may cause endocardial fibrosis. Endocardial fibrosis and overlying thrombus typically lead to a restrictive cardiomyopathy and heart failure. Occasionally mitral or tricuspid regurgitation (or both) occurs as a result of the fibrosis and thrombus formation. This report describes a patient with hypereosinophilic syndrome who was seen with an unusually localized form of cardiac involvement that resulted in predominantly aortic and mitral stenosis. This was treated with bivalvular replacement.
authors.affiliation: Division of Cardio-Thoracic Surgery, Emory University School of Medicine, Atlanta, GA 30322.
authors.forename: W G
authors.initials: WG
authors.lastname: Hendren
authors.forename: E L
authors.initials: EL
authors.lastname: Jones
authors.forename: M D
authors.initials: MD
authors.lastname: Smith
mesh_terms: D000328:Adult; D001024:Aortic Valve Stenosis / Q000601:surgery*; D004719:Endomyocardial Fibrosis / Q000601:surgery; D004802:Eosinophilia / Q000601:surgery*; D006801:Humans; D008297:Male; D008946:Mitral Valve Stenosis / Q000601:surgery*; D013577:Syndrome