[Carney's complex (myxomas, pigmented spots and endocrine hyperactivity). Apropos of a partial form in monozygotic twins].
The authors describe monozygotic twins with right ventricular myxoma, one of whom had cutaneous myxomas, large cell calcifying Sertoli cell tumor of the testis (a lesion which was certainly latent in his brother) and recurrent cardiac myxoma. These elements are manifestations of "Carney's complex". This recently reported inherited syndrome should be recognized by pathologists because of major risk of cardiac myxoma. Cutaneous lesions, specially cutaneous myxomas, are heralds of this syndrome.
Gaillard
F
F
Laboratoire d'Anatomie Pathologique A, Hôtel Dieu, Nantes.
Bouc
M
M
de Lajartre
A Y
AY
Audouin
A F
AF
Nomballais
M F
MF
Mussini-Montpellier
J
J
D000293:Adolescent; D006338:Heart Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009232:Myxoma / Q000150:complications* / Q000473:pathology; D012707:Sertoli Cell Tumor / Q000150:complications* / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D013577:Syndrome; D013736:Testicular Neoplasms / Q000150:complications* / Q000473:pathology; D014430:Twins, Monozygotic
Le complexe de Carney (myxomes, taches pigmentaires et hyperactivité endocrinienne). A propos d'une forme partielle chez des jumeaux monozygotes.