[Imipramine antibodies in endogenous depression in young people].
The drug antibodies were radioimmunologically detected in 58.3% of depressive patients treated with Imipramine. A group of patients with the antibodies permanently present either proved fully resistant or showed a minor effect. A group with antibodies arising just at the start of the treatment displayed either complete remission or substantial improvement. Antibodies were not found in patients exhibiting full recovery or considerable improvement.
Kushner
S G
SG
Koliaskina
G I
GI
Tsutsul'kovskaia
M Ia
MIa
Fomenko
A M
AM
Vladimirova
T V
TV
D000328:Adult; D000906:Antibodies / Q000032:analysis*; D003866:Depressive Disorder / Q000188:drug therapy / Q000276:immunology*; D004351:Drug Resistance; D006801:Humans; D007099:Imipramine / Q000276:immunology*; D011863:Radioimmunoassay; D013997:Time Factors
D000906:Antibodies; D007099:Imipramine
Antitela k imipraminu pri éndogennykh depressiiakh iunosheskogo vozrasta.