Aldosterone deficiency in infancy.
Two infants with a chronic salt wasting state secondary to a rare defect in mineralocorticoid synthesis are described. Management difficulties are illustrated highlighting the need for early definitive diagnosis based on measurement and correct interpretation of plasma renin, plasma aldosterone and urinary steroid metabolite concentrations.
Glass
I A
IA
Department of Medicine, Royal Hospital for Sick Children, Yorkhill, Glasgow.
Wallace
A M
AM
Beattie
T J
TJ
D000305:Adrenal Cortex Hormones / Q000097:blood; D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis*; D000450:Aldosterone / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D005438:Fludrocortisone / Q000627:therapeutic use; D006801:Humans; D006994:Hypoaldosteronism / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy; D007223:Infant; D007231:Infant, Newborn; D012964:Sodium / Q000652:urine
D000305:Adrenal Cortex Hormones; D000450:Aldosterone; D012964:Sodium; D005438:Fludrocortisone