A frequency-specific auditory brainstem response technique exemplified in the determination of age-related auditory thresholds.
Using gated sinusoidal stimuli (tone bursts), frequency-specific auditory brainstem responses (ABR) have been recorded in mice. The gating function represents a filter with a constant narrow bandwidth in the investigated frequency range 2-31.5 kHz. The ABR thresholds found in the CBA/CBA mouse using this technique were in close agreement with those previously reported in the literature concerning mice. The ABR thresholds were analysed in 2-18-month-old animals showing a slight impairment of ABR thresholds with increasing age. The individual variations in ABR thresholds were small.
Wenngren
B I
BI
Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University Hospital, Umeå, Sweden.
Anniko
M
M
D000375:Aging / Q000502:physiology*; D000818:Animals; D001300:Audiometry, Evoked Response / Q000379:methods; D001309:Auditory Threshold / Q000502:physiology*; D005072:Evoked Potentials, Auditory; D051379:Mice; D008808:Mice, Inbred CBA