title: Oral vancomycin in prevention of necrotising enterocolitis.
abstract: Eighty four very low birthweight babies (considered high risk for developing necrotising enterocolitis) were given vancomycin orally for 48 hours before introduction of oral feeds; one developed necrotising enterocolitis. One hundred and twenty very low birthweight babies (not considered such high risk) were fed without first receiving vancomycin; 17 developed necrotising enterocolitis. Although this was not a randomised control trial, results indicate a role for vancomycin in prophylaxis of necrotising enterocolitis.
authors.affiliation: Department of Paediatrics and Child Health, St James's University Hospital, Leeds.
authors.forename: P C
authors.initials: PC
authors.lastname: Ng
authors.forename: P R
authors.initials: PR
authors.lastname: Dear
authors.forename: D F
authors.initials: DF
authors.lastname: Thomas
mesh_terms: D000284:Administration, Oral; D004761:Enterocolitis, Pseudomembranous / Q000517:prevention & control*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000517:prevention & control*; D014640:Vancomycin / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014640:Vancomycin