Oral contraceptives and intrahepatic biliary cystadenoma having an increased level of estrogen receptor.
We report a case of intrahepatic biliary cystadenoma in a young woman who had no prior history of liver disease and who had taken oral contraceptives for one year. A 27-year-old woman was admitted to our hospital with a firm epigastric mass. At laparotomy, a large cystic mass was resected from the left hepatic lobe, and diagnosed as biliary cystadenoma. In the tumor tissue, the estrogen receptor content was 14.0 fmol/mg cytosol protein, which was much higher than the 3.0 fmol/mg cytosol protein in the surrounding liver tissue. This is the first case of biliary cystadenoma in which the estrogen receptor content was increased.
Suyama
Y
Y
Second Department of Internal Medicine, Tottori University School of Medicine.
Horie
Y
Y
Suou
T
T
Hirayama
C
C
Ishiguro
M
M
Nishimura
O
O
Koga
S
S
D000328:Adult; D001650:Bile Duct Neoplasms / Q000032:analysis / Q000139:chemically induced*; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects*; D003537:Cystadenoma / Q000032:analysis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008234:Lynestrenol; D008656:Mestranol; D011960:Receptors, Estrogen / Q000032:analysis*
D003277:Contraceptives, Oral, Combined; D011960:Receptors, Estrogen; D008656:Mestranol; D008234:Lynestrenol