title: A large outbreak of mumps in the postvaccine era.
abstract: During a county-wide mumps outbreak in Nashville, Tennessee, 332 cases of mumps were identified at a public high school (attack rate, 18.8%). A pep rally 17 d before the peak of the outbreak at a single public high school may have provided an opportunity for point-source exposure. A case-control study demonstrated that vaccine efficacy was 75% (we used provider-verified records and excluded students with a history of mumps disease). Although school records were nonuniform, mumps immunization status was correct, compared with provider-verified records, in at least 85% of both cases and controls. Parental reports were much less reliable. The cost of the outbreak was estimated at $154/case. Receiving mumps vaccine at a vaccine clinic held after the outbreak had peaked was associated with a decrease in risk of mumps disease. Thus, these clinics may have a role in the control of such outbreaks.
authors.affiliation: Division of Field Services, Centers for Disease Control, Atlanta, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Wharton
authors.forename: S L
authors.initials: SL
authors.lastname: Cochi
authors.forename: R H
authors.initials: RH
authors.lastname: Hutcheson
authors.forename: J M
authors.initials: JM
authors.lastname: Bistowish
authors.forename: W
authors.initials: W
authors.lastname: Schaffner
mesh_terms: D000293:Adolescent; D002648:Child; D003365:Costs and Cost Analysis; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007114:Immunization; D008297:Male; D009107:Mumps / Q000191:economics / Q000453:epidemiology*; D009108:Mumps Vaccine; D012307:Risk Factors; D013714:Tennessee
chemical_list: D009108:Mumps Vaccine