title: [Localized scleroderma in childhood].
abstract: Scleroderma is a rare disease in children: the clinical presentation in childhood is even more varied than in adult life. It is characterized by 'hard skin' with cutaneous features including hypo- and hyperpigmentation, thickening or thinning and loss of elasticity. It ranges from circumscribed and self-limiting pigmentary disorders to disabling and disfiguring involvement of an extremity and a rapidly fatal outcome. Scleroderma must be differentiated from many scleroderma-like conditions. Therapeutic problems are also discussed.
authors.affiliation: Divisione di Pediatria, Ospedale di Lucca, Italia.
authors.forename: R
authors.initials: R
authors.lastname: Domenici
authors.forename: F
authors.initials: F
authors.lastname: Simoni
authors.forename: G
authors.initials: G
authors.lastname: Camici
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D012594:Scleroderma, Localized / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents
vernacular_title: Sclerodermia localizzata nell'infanzia.