Dopamine agonist treatment of self-induced pattern-sensitive epilepsy. A case report.
Abusing his own pattern sensitivity, a mentally retarded boy displayed frequent self-induced seizures resistant to conventional anticonvulsive treatment. Bromocriptine and fenfluramine have been successful in terminating self-induced seizures by means of blocking the photosensitive triggering mechanism. Secondary to this effect, the pathological drive toward seizures diminished. The possible mechanism of action has been discussed briefly.
Clemens
B
B
County Hospital, Neurology Unit, Debrecen, Hungary.
D001971:Bromocriptine / Q000627:therapeutic use*; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000188:drug therapy* / Q000503:physiopathology; D005277:Fenfluramine / Q000627:therapeutic use*; D005556:Form Perception / Q000502:physiology*; D006801:Humans; D008297:Male; D010364:Pattern Recognition, Visual / Q000187:drug effects / Q000502:physiology*; D010567:Pertussis Vaccine / Q000009:adverse effects; D010775:Photic Stimulation; D012653:Self Stimulation / Q000187:drug effects*; D014795:Visual Pathways / Q000502:physiology*
D010567:Pertussis Vaccine; D005277:Fenfluramine; D001971:Bromocriptine