[Intraoperative sedation by midazolam during spinal anesthesia. A study of elderly women undergoing surgery of the hip and femur neck].
Midazolam was studied as an IV sedative agent in 30 women aged of 75 years or more, undergoing hip surgery or Ender nailing, who received a spinal anaesthesia with 15 mg of plain bupivacaine. A mean dose of midazolam 0.077 mg.kg-1 was required to induce adequate sedation which was maintained by repeated doses of 2.5 mg. Post-operatively, no somnolence was noted at 2 hr. A marked amnesic effect was observed in 77% of cases. No clinically adverse cardiovascular or respiratory effects were encountered. It is concluded that midazolam is a useful sedative agent for spinal anaesthesia of short duration in the elderly.
Racle
J P
JP
Service d'anesthésiologie, Centre hospitalier de Chalon-sur-Saône.
Cenon
E
E
Jourden
L
L
Benkhadra
A
A
Poy
J Y
JY
Fockenier
F
F
D000368:Aged; D000369:Aged, 80 and over; D000775:Anesthesia, Spinal; D005260:Female; D005265:Femoral Neck Fractures / Q000601:surgery*; D005594:Fracture Fixation, Intramedullary; D006622:Hip Prosthesis; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007432:Intraoperative Period; D008874:Midazolam / Q000008:administration & dosage*
D006993:Hypnotics and Sedatives; D008874:Midazolam
Sédation per-opératoire par le midazolam au cours des rachianesthésies. Etude chez la femme âgée en chirurgie de la hanche et du col du fémur.