Human maximization test of falcarinol, the principal contact allergen of English ivy and Algerian ivy (Hedera helix, H. canariensis).
In a human maximization test of 5% falcarinol isolated from Hedera helix, 10 of 20 subjects were sensitized. No subjects gave irritant reactions to 5%, 10 became sensitive to 1%, and 7 to 0.05%, with 3 of these giving 3+ to 4+ bullous reactions.
Gafner
F
F
Department of Developmental and Cell Biology, University of California, Irvine 92717.
Epstein
W
W
Reynolds
G
G
Rodriguez
E
E
D000480:Alkynes; D000485:Allergens; D000818:Animals; D003877:Dermatitis, Contact / Q000209:etiology*; D053280:Diynes; D005233:Fatty Alcohols / Q000633:toxicity*; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D010328:Patch Tests; D010944:Plants / Q000276:immunology*
D000480:Alkynes; D000485:Allergens; D053280:Diynes; D005233:Fatty Alcohols; C018541:falcarinol