title: [Comparative study of platinum complexes in athymic mice with human tumors].
abstract: Tumoricidal activity of Soviet-synthesized oxoplatinum and cycloplatam was shown to influence human tumor strains (melanoma, cancer of the kidney, Burkitt's lymphoma) transplanted to nude mice. Their therapeutic effect was associated with lymphopenia; however, they did not suppress the chemically determined activity of succinate dehydrogenase and alpha-glycerophosphate dehydrogenase.
authors.forename: I K
authors.initials: IK
authors.lastname: Bukharov
authors.forename: L I
authors.initials: LI
authors.lastname: Osokina
authors.forename: E S
authors.initials: ES
authors.lastname: Revazova
authors.forename: L V
authors.initials: LV
authors.lastname: Moroz
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002051:Burkitt Lymphoma / Q000188:drug therapy; D002945:Cisplatin / Q000031:analogs & derivatives / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy; D008545:Melanoma / Q000188:drug therapy; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D009944:Organoplatinum Compounds / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; C055928:cycloplatam; D002945:Cisplatin; C043804:diamminedichlorodihydroxyplatinum IV
vernacular_title: Sravnitel'noe izuchenie kompleksov platiny na bestimusnykh myshakh s opukholiami cheloveka.