[Kinetics of the transport of substances with various molecular weights from the blood into the lymph of the lungs (the role of transendothelial and interstitial mass transfer)].
To study the transport kinetics, 10 experiments on canine isolated lung preparations were performed using tritium-labeled lipopolysaccharide, Evans blue dye, fluorescein and tritium-labeled water as mass transfer markers. The markers with high molecular weight were more rapidly transported through interstitium than those with low molecular weight. The data obtained corroborate the thesis that the distribution of substances in the interstitium follows the laws of diffusion and convection in porous phase. Active functioning of the endothelium structures also affects the blood-to-lymph transport.
Serikov
V B
VB
Sukhin
A B
AB
Selivanov
D B
DB
D000818:Animals; D001692:Biological Transport; D015415:Biomarkers / Q000097:blood; D001769:Blood / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D004285:Dogs; D004727:Endothelium / Q000378:metabolism; D005260:Female; D066298:In Vitro Techniques; D007700:Kinetics; D008168:Lung / Q000378:metabolism*; D008196:Lymph / Q000378:metabolism*; D008297:Male; D008970:Molecular Weight; D014316:Tritium
D015415:Biomarkers; D014316:Tritium
Kinetika transporta veshchestv razlichnoĭ molekuliarnoĭ massy iz krovi v limfu legkikh (rol' transéndotelial'nogo i interstitsial'nogo massoperenosa.