An optimal design problem in rhythmometry.
A trigonometric regression model is assumed for a problem involving circadian rhythm exhibited by peak expiratory flow. Experimental designs are sought with a view to estimating a particular nonlinear function of the parameters. Both optimal and nonoptimal, but more practicable, designs are derived and their relative efficiencies are established.
Kitsos
C P
CP
Department of Statistics, University of Glasgow, Scotland, U.K.
Titterington
D M
DM
Torsney
B
B
D002940:Circadian Rhythm; D008433:Mathematics; D008954:Models, Biological; D010366:Peak Expiratory Flow Rate