[Ultrastructure of HeLa cella after exposure to nickel ions].
Dose-dependent progress of destructive processes (mitochondria destruction, proteolysis, autophagocytosis) is observed in HeLa cells treated with various concentrations of nickel (0.05-4 micrograms/ml) for 2, 4 and 24 hours. Parallel with it the compensation and adaptation responses of cells (increase of mitochondrion polymorphism, appearance of "macropolysomes", hypertrophy of the Golgi complex) take place.
Iurova
A V
AV
Strochkova
L S
LS
Zhavoronkov
A A
AA
D001343:Autophagy / Q000187:drug effects; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure; D004305:Dose-Response Relationship, Drug; D004721:Endoplasmic Reticulum / Q000187:drug effects / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000187:drug effects / Q000648:ultrastructure; D006367:HeLa Cells / Q000187:drug effects*; D006801:Humans; D008854:Microscopy, Electron; D008928:Mitochondria / Q000187:drug effects / Q000648:ultrastructure; D009532:Nickel / Q000494:pharmacology*; D012270:Ribosomes / Q000187:drug effects / Q000648:ultrastructure; D013997:Time Factors
D009532:Nickel
Izuchenie ul'trastruktury kletok HeLa posle vozdeĭstviia iona nikelia.