title: Novel antifungal antibiotics octacosamicins A and B. II. The structure elucidation using various NMR spectroscopic methods.
abstract: The structures of octacosamicins A and B, two new antifungal antibiotics, were studied by spectrometries and chemical modifications. The 2D NMR techniques including 1H-detected heteronuclear multiple bond correlation method were successfully applied to this study. These antibiotics have unique linear chain structure possessing N-hydroxyguanidyl group at the terminal.
authors.affiliation: Institute of Microbial Chemistry, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Dobashi
authors.forename: H
authors.initials: H
authors.lastname: Naganawa
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Takita
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
mesh_terms: D000935:Antifungal Agents; D055598:Chemical Phenomena; D002621:Chemistry; D006146:Guanidines / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy
chemical_list: D000935:Antifungal Agents; D006146:Guanidines; C058021:octacosamicin B; C058020:octacosamicin A