title: [Annual rhythm of the excretion of indole melanogen in human urine].
abstract: Comparing the monthly indole melanogen mean values (4,100 single values within 5 years) in patients with malignant melanomas showing a normal urinary indole melanogen concentration we have found a seasonal effect with a maximum melanogen excretion in spring (March) and summer (July) and a minimum in autumn (September). These results are statistically significant. The possible importance of these seasonal influences for the prognosis in individual cases of malignant melanoma is discussed.
authors.affiliation: Klinik und Poliklinik für Hautkrankheiten der Bereiches Medizin, Martin-Luther-Universität Halle, Wittenberg.
authors.forename: G
authors.initials: G
authors.lastname: Schwartze
mesh_terms: D006801:Humans; D007211:Indoles / Q000652:urine*; D008545:Melanoma / Q000652:urine*; D010507:Periodicity
chemical_list: D007211:Indoles; C009904:melanogen
vernacular_title: Jahresrhythmik der Ausscheidung von Indolmelanogenen im menschlichen Harn.