Self-assembly of porphyrins on nucleic acid templates.
The cis and trans isomers of dicationic bis(4-N-methylpyridyl)diphenylporphine show a much greater tendency to aggregate than similar tetracationic porphyrins. Upon binding to nucleic acids these aggregating dicationic porphyrins form long-range structures on the polymer template giving intense circular dichroism signals whose profile reports the helical sense of the DNA.
Gibbs
E J
EJ
Department of Chemistry, Goucher College, Towson, MD 21204.
Tinoco
I
I
Maestre
M F
MF
Ellinas
P A
PA
Pasternack
R F
RF
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002942:Circular Dichroism; D009690:Nucleic Acid Conformation; D009696:Nucleic Acids; D011166:Porphyrins; D012965:Sodium Chloride; D013057:Spectrum Analysis
D009696:Nucleic Acids; D011166:Porphyrins; D012965:Sodium Chloride