title: Frequency of early-morning rise in blood glucose in children with diabetes at camp.
abstract: To estimate the frequency of an early-morning glucose rise (EMR) in relatively unselected children with insulin-dependent diabetes mellitus (IDDM), we assessed capillary blood glucose (CBG) at midsleep (0200-0430) and prebreakfast (0700-0800) in 97 children with diabetes at camp. The EMR (prebreakfast CBG-midsleep CGB) was inversely related to the midsleep CBG level (r = -.45, P less than .001). Of the 49 children with midsleep CBG less than 200 mg/dl, the mean EMR was 34 +/- 60 mg/dl, and 18 of these children had rises of greater than 40 mg/dl. In conclusion, when midsleep glycemia is less than 200 mg/dl, a rise in blood glucose from midsleep to prebreakfast, often greater than 40 mg/dl, is a common element of glycemic control among children with IDDM. The relative importance of the Somogyi phenomenon, the dawn phenomenon, and mere insulin insufficiency in the early-morning hours cannot be determined from these data.
authors.affiliation: Department of Epidemiology, University of North Carolina, Chapel Hill.
authors.forename: B B
authors.initials: BB
authors.lastname: Duncan
authors.forename: M I
authors.initials: MI
authors.lastname: Schmidt
authors.forename: G J
authors.initials: GJ
authors.lastname: Ellis
authors.forename: C E
authors.initials: CE
authors.lastname: Davis
authors.forename: G
authors.initials: G
authors.lastname: Heiss
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis*; D002165:Camping; D002648:Child; D002940:Circadian Rhythm; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D006801:Humans; D012890:Sleep
chemical_list: D001786:Blood Glucose