[Anticooperative interactions between the nearest neighbor chromatosomes].
A model which permits the description of chromatosomes distribution along the DNA were developed. The experimental data on the spacing of chromatosomes on rat liver chromatin were analysed. It was shown that chromatosomes dimers spaced at less than 40 base pairs are encountered more rarely than might be expected on the basis of a random distribution of chromatosomes along DNA. We propose that between nearest neighbor chromatosomes in the fibre there exist interactions which hinder the rapprochement of chromatosomes. The data analysis put forth in this paper permits us to determine the energetic parameters of such anticooperative interactions.
Nechipurenko
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IuD
D000818:Animals; D001482:Base Composition; D002843:Chromatin; D004247:DNA; D006657:Histones; D008099:Liver; D009690:Nucleic Acid Conformation; D009707:Nucleosomes; D011487:Protein Conformation; D051381:Rats
D002843:Chromatin; D006657:Histones; D009707:Nucleosomes; D004247:DNA
Antikooperativnye vzaimodeĭstviia mezhdu blizhaĭshimi sosednimi khromatosomami.