Tumor promoter-inducible genes are differentially expressed in the developing mouse.
TIS genes are rapidly and transiently induced by tetradecanoyl phorbol acetate in 3T3 cells. We analyzed the developmental appearance of a number of the TIS genes to determine whether, in a normal physiological context, these genes have common or distinct mechanisms of regulation. Each TIS gene has a distinct tissue specificity and/or developmental profile.
Tippetts
M T
MT
Department of Biological Chemistry, University of California, Los Angeles 90024.
Varnum
B C
BC
Lim
R W
RW
Herschman
H R
HR
D000818:Animals; D015152:Blotting, Northern; D005786:Gene Expression Regulation / Q000187:drug effects*; D051379:Mice / Q000196:embryology* / Q000235:genetics; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*; D014018:Tissue Distribution
D013755:Tetradecanoylphorbol Acetate