title: Identification of the phyto-oestrogen 3',7-dihydroxyisoflavan, an isomer of equol, in human urine and cow's milk.
abstract: The isoflavonoid diphenol 3',7-dihydroxyisoflavan, an isomer of the known compound equol (4',7-dihydroxyisoflavan), has been identified in human urine and in cow's milk. The compound was isolated as the glucuronide, purified by column chromatography and identified after hydrolysis to the aglycon. The trimethylsilyl ether derivative was characterized by comparison of its mass spectrum and chromatographic properties with those of synthesized silylated isomers of equol.
authors.affiliation: Department of Clinical Chemistry, University of Helsinki, Finland.
authors.forename: C
authors.initials: C
authors.lastname: Bannwart
authors.forename: H
authors.initials: H
authors.lastname: Adlercreutz
authors.forename: K
authors.initials: K
authors.lastname: Wähälä
authors.forename: T
authors.initials: T
authors.lastname: Kotiaho
authors.forename: A
authors.initials: A
authors.lastname: Hesso
authors.forename: G
authors.initials: G
authors.lastname: Brunow
authors.forename: T
authors.initials: T
authors.lastname: Hase
mesh_terms: D000818:Animals; D001578:Benzopyrans / Q000032:analysis*; D002417:Cattle; D002839:Chromans / Q000032:analysis* / Q000652:urine; D060754:Equol; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007529:Isoflavones; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008892:Milk / Q000032:analysis*; D008996:Monoamine Oxidase Inhibitors / Q000032:analysis* / Q000652:urine
chemical_list: C007610:4',7-dihydroxy-3,4-dihydroisoflavone; D001578:Benzopyrans; D002839:Chromans; D007529:Isoflavones; D008996:Monoamine Oxidase Inhibitors; D060754:Equol; C058142:3',7-dihydroxyisoflavan