title: Erythrocyte protein 4.1 associates with tubulin.
abstract: Protein 4.1 binds to tubulin, as determined by sedimentation and immunoelectron-microscopy analyses, at a molar ratio similar to that described for brain microtubule-associated proteins. The binding site appears to be located at the C-terminal region of tubulin. Experiments performed in situ by adding exogenous protein 4.1 to permeabilized 3T3 cells show that this protein binds to microtubule and nuclear components.
authors.affiliation: Centro de Biología Molecular (CSIC-UAM), Universidad Autónoma, Madrid, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Correas
authors.forename: J
authors.initials: J
authors.lastname: Avila
mesh_terms: D000818:Animals; D003598:Cytoskeletal Proteins; D004591:Electrophoresis, Polyacrylamide Gel; D004910:Erythrocyte Membrane / Q000378:metabolism*; D015151:Immunoblotting; D008565:Membrane Proteins / Q000378:metabolism* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008870:Microtubules / Q000378:metabolism / Q000648:ultrastructure; D009479:Neuropeptides; D011485:Protein Binding; D014404:Tubulin / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D003598:Cytoskeletal Proteins; D008565:Membrane Proteins; D009479:Neuropeptides; D014404:Tubulin; C028841:erythrocyte membrane band 4.1 protein; C120557:erythrocyte membrane protein band 4.1-like 1