HLA antigens and Adamantiades-Behçet's disease (A-BD) in Greeks.
The distribution frequency of HLA-A and B antigens was determined in 24 Greek individuals with Adamantiades-Behçet's disease (A-BD) as well as in 280 controls. The standard NIH technique was used for tissue typing. There was an increased incidence of HLA-B5 in the patients group (75% compared to controls 32%). The calculated P corrected value was Pc less than 0.02, the relative risk (RR) was 6.23 and the aetiological fraction (EF) 0.68. This study agrees with the reported association between A-BD and HLA-B5 in other populations from the Mediterranean basin, the Middle East and Far East.
Zervas
J
J
First Department of Medicine, University of Athens, Laikon General Hospital, Greece.
Vayopoulos
G
G
Sakellaropoulos
N
N
Kaklamanis
P
P
Fessas
P
P
D000328:Adult; D001528:Behcet Syndrome / Q000208:ethnology / Q000276:immunology*; D005260:Female; D006115:Greece; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged
D006680:HLA Antigens