title: Stimulation of sea star Asterias rubens axial organ B-like cells by Nocardia-delipidated cell mitogen and derived fractions.
abstract: The axial organ (AO-cells) of the starfish Asterias rubens is a primitive immune organ. The total population was fractionated into two populations: adherent (B-like) and non-adherent (T-like) to nylon wool. Nocardia-delipidated cell mitogen (NDCM), Nocardia water soluble mitogen (NWSM), NWSM-pellet (NWSMP) and purified cell walls (CW) from Nocardia opaca induce the proliferation of B-like cells from the axial organ. The Nocardia immunomodulators studied are inactive on the total and T-like population. The mitogenic activity of B-like cells requires the presence of phagocytic cells.
authors.affiliation: Département de Biologie, Université d'Orléans, France.
authors.forename: M
authors.initials: M
authors.lastname: Leclerc
authors.forename: T
authors.initials: T
authors.lastname: Bahmaoud
authors.forename: C
authors.initials: C
authors.lastname: Brillouet
authors.forename: H
authors.initials: H
authors.lastname: Tlaskalová-Hogenová
authors.forename: J F
authors.initials: JF
authors.lastname: Petit
authors.forename: R
authors.initials: R
authors.lastname: Barot-Ciorbaru
mesh_terms: D000818:Animals; D002455:Cell Division; D002470:Cell Survival; D002473:Cell Wall / Q000502:physiology; D002478:Cells, Cultured; D004261:DNA Replication; D008934:Mitogens / Q000494:pharmacology*; D009615:Nocardia; D013215:Starfish / Q000166:cytology / Q000502:physiology*; D013936:Thymidine / Q000378:metabolism
chemical_list: D008934:Mitogens; D013936:Thymidine