Duplication of a small segment of 5p due to maternal recombination within a paracentric shift.
Duplication of chromosome sub-bands 5p14.3 and 5p15.1 in a child resulted in mild mental retardation, apparently without other abnormalities. The duplicated region arises from recombination within a directly inserted segment following a shift within the short arm of the maternal chromosome 5 homologs.
Webb
G C
GC
Department of Genetics, Royal Children's Hospital, Melbourne, Australia.
Voullaire
L E
LE
Rogers
J G
JG
D002648:Child; D002869:Chromosome Aberrations; D002895:Chromosomes, Human, Pair 5; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D008540:Meiosis; D011995:Recombination, Genetic