title: A case of death from prothiophos poisoning.
abstract: A 62-year-old male, a farmer, who had ingested prothiophos (Tokuthion), died after 21 h of intensive care. Prothiophos in the tissues of the victim was extracted and purified by Extrelut column extraction. A gas chromatograph equipped with a flame photometric detector, and a gas chromatograph-mass spectrometer were used to detect prothiophos. The concentration of prothiophos was 10.9 micrograms/g in the brain, 8.6 micrograms/g in the kidney, 418 micrograms/g in the liver, 2.96 mg/g in the gastric contents and 4.69 mg/g in the intestinal contents. The case history and the distribution of prothiophos indicated that the cause of death was acute prothiophos poisoning.
authors.affiliation: Department of Legal Medicine, Hiroshima University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Miyazaki
authors.forename: M
authors.initials: M
authors.lastname: Yashiki
authors.forename: F
authors.initials: F
authors.lastname: Chikasue
authors.forename: T
authors.initials: T
authors.lastname: Kojima
authors.forename: H
authors.initials: H
authors.lastname: Hibino
mesh_terms: D001923:Brain Chemistry; D003128:Coma / Q000209:etiology; D008401:Gas Chromatography-Mass Spectrometry; D005766:Gastrointestinal Contents / Q000032:analysis; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008297:Male; D008875:Middle Aged; D062025:Organophosphate Poisoning; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds / Q000506:poisoning*
chemical_list: D007306:Insecticides; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds; C032072:prothiophos