[Use of liposomes for correction of respiratory hypoxia in experimental pneumonia].
White laboratory rats, weighted 100-160 g, with acute pneumonia, inhale (from 4-th to 8-th days of developing the disease) liposomes. It was shown, that introduction of liposomes promoted normalization of external breath, acid-base state of blood, increased diffusion ability of lung for O2 and decreased arterial hypoxia. It was noted, that liposomes are an effective antihypoxant, inhibited the process of lipid peroxidation and, evidently, the destruction of cell membranes.
Bryginskiĭ
S A
SA
Zubarenko
A V
AV
Lishko
V K
VK
Miniaĭlenko
T D
TD
Pozharov
V P
VP
D000818:Animals; D000860:Hypoxia / Q000209:etiology / Q000628:therapy*; D007773:Lactates / Q000097:blood; D015227:Lipid Peroxidation; D008081:Liposomes; D008315:Malondialdehyde / Q000097:blood; D011014:Pneumonia / Q000150:complications / Q000503:physiopathology*; D011653:Pulmonary Diffusing Capacity; D051381:Rats; D012138:Respiratory Therapy / Q000295:instrumentation / Q000379:methods; D014464:Ultrasonic Therapy
D007773:Lactates; D008081:Liposomes; D008315:Malondialdehyde
Primenenie liposom dlia korrektsii respiratornoĭ gipoksii pri éksperimental'noĭ pnevmonii.