[The microbial factor in the chemiluminescence of the peripheral blood neutrophils of patients with suppurative surgical infection].
The luminol-dependent chemiluminescence of neutrophils in the peripheral blood of 30 healthy adults and 39 patients with the local and generalized forms of purulent infection was studied. Nonstimulated chemiluminescence and the index of chemiluminescence stimulation in the presence of opsonized Staphylococcus aureus added in vitro were determined. The former characteristic was found to be directly and the latter one, inversely related to the concentration of S. aureus, Escherichia coli and Candida albicans, but not E. epidermidis, Pseudomonas aeruginosa or Citrobacter, in the primary focus. At the microbial concentration exceeding 10(4) cells/g of tissue, the former characteristic was essentially higher than the level of chemiluminescence in healthy persons. With the improvement of the general state of the patients and in the absence of microorganisms in the wound as the result of complex treatment this characteristic decreased to values comparable with the reaction of neutrophils in healthy persons.
Belotskiĭ
S M
SM
Snastina
T I
TI
Filiukova
O B
OB
Zviagin
A A
AA
D001424:Bacterial Infections / Q000097:blood* / Q000382:microbiology; D002177:Candidiasis / Q000097:blood / Q000382:microbiology; D006801:Humans; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology; D009504:Neutrophils / Q000187:drug effects / Q000378:metabolism* / Q000382:microbiology; D009895:Opsonin Proteins / Q000276:immunology; D010100:Oxygen / Q000097:blood
D009895:Opsonin Proteins; D008165:Luminol; D010100:Oxygen
Mikrobnyĭ faktor khemiliuminestsentsii neĭtrofilov perifericheskoĭ krovi bol'nykh s gnoĭnoĭ khirurgicheskoĭ infektsieĭ.