Identification of a connective tissue degrading enzyme in bovine inflammatory exudate.
Chronic inflammation and the associated tissue damage are of major concern to medical and veterinary clinicians. It is likely that proteinases are the important enzymes in the pathological degradation of connective tissues. A neutral metalloproteinase, capable of degrading proteoglycans, has been identified in its active form in acute inflammatory exudates.
May
S A
SA
Department of Veterinary Basic Sciences, Royal Veterinary College, North Mymms, Hatfield, Herts.
Hooke
R E
RE
Lees
P
P
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000201:enzymology* / Q000503:physiopathology; D003238:Connective Tissue / Q000503:physiopathology*; D005122:Exudates and Transudates / Q000201:enzymology*; D007249:Inflammation / Q000201:enzymology / Q000503:physiopathology / Q000662:veterinary*; D008666:Metalloendopeptidases / Q000032:analysis / Q000302:isolation & purification*
D008666:Metalloendopeptidases