Outer membrane permeation of Bacteroides fragilis by cephalosporins.
Outer membrane permeation of Bacteroides fragilis by cephalosporins was examined by a previously described method. The permeation parameters of cephalosporins in B. fragilis were close to 10(-5) cm3/min per microgram of cell dry weight. These values were about an order of magnitude lower than those in Escherichia coli. In B. fragilis, the permeation was not directly proportional to the hydrophilicity of cephalosporins, and the ion selectivity was weak.
Yotsuji
A
A
Research Laboratory, Toyama Chemical Co., Ltd., Japan.
Mitsuyama
J
J
Hori
R
R
Yasuda
T
T
Saikawa
I
I
Inoue
M
M
Mitsuhashi
S
S
D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism; D001441:Bacteroides fragilis / Q000378:metabolism*; D002463:Cell Membrane Permeability; D002511:Cephalosporins / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D008564:Membrane Potentials
D001425:Bacterial Outer Membrane Proteins; D002511:Cephalosporins