[Coupled thermoregulatory and hemodynamic effects in the central administration of bombesin].
C-terminal nonapeptide of bombesin introduced into the rabbit brain lateral ventricle increased the arterial pressure by 21.5 mm Hg while decreasing the heart rate by 89.5 min-1. Comparison of these findings with earlier data on the effect of bombesin on peripheral blood flow and gastrointestinal functions suggested a reciprocal effect of bombesin on the tone of vegetative (mainly sympathetic) spinal neurons.
Mar'ianovich
A T
AT
Shipilov
Iu I
IuI
Tsygan
V N
VN
D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects*; D001839:Bombesin / Q000008:administration & dosage* / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects*; D007276:Injections, Intraventricular; D008297:Male; D008959:Models, Neurological; D009474:Neurons / Q000187:drug effects; D011817:Rabbits; D013116:Spinal Cord / Q000187:drug effects
D001839:Bombesin
Sopriazhennye termoreguliatsionnye i gemodinamicheskie éffekty pri tsentral'nom vvedenii bombezina.