[Wound infection following appendectomy. Metronidazole vs ornidazole as single-dose prophylaxis in non-perforated appendix].
In an open prospective randomized study, the postoperative wound infection rate following removal of an unperforated appendix was evaluated in 187 patients who received either metronidazole (1 g suppositories) or ornidazole (500 mg iv or 500 mg suppositories) in a single dose preoperatively. The overall postoperative infection rate was 2.1%. Metronidazole and ornidazole suppositories are a cheap method of preventing postoperative infection in cases of unperforated appendix.
Barth
A
A
Chirurgische Klinik, Bürgerspital Solothurn.
Kuhn
P
P
Bertschmann
W
W
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001064:Appendicitis / Q000150:complications; D002648:Child; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage*; D008875:Middle Aged; D009593:Nitroimidazoles / Q000008:administration & dosage*; D009950:Ornidazole / Q000008:administration & dosage*; D011446:Prospective Studies; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000517:prevention & control*
D009593:Nitroimidazoles; D008795:Metronidazole; D009950:Ornidazole
Wundinfekte nach Appendektomie. Metronidazol vs Ornidazol als Einmalprophylaxe bei nicht-perforierter Appendix.