title: Circumscribed lytic lesions of the thalassaemic skull.
abstract: Solitary or multiple circumscribed osteolytic areas are described in seven patients, selected from 250 patients with homozygous beta-thalassaemia (Cooley's anaemia). On X-ray examinations, these areas appear as purely osteolytic lesions with well-defined margins not associated with sclerosis. The possible mechanisms are discussed.
authors.affiliation: Department of Radiology, St. Anna Hospital, Ferrara, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Orzincolo
authors.forename: G
authors.initials: G
authors.lastname: Castaldi
authors.forename: L
authors.initials: L
authors.lastname: Bariani
authors.forename: F
authors.initials: F
authors.lastname: Franceschini
authors.forename: S
authors.initials: S
authors.lastname: Corcione
authors.forename: P N
authors.initials: PN
authors.lastname: Scutellari
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010014:Osteolysis / Q000000981:diagnostic imaging* / Q000209:etiology; D011859:Radiography; D012886:Skull / Q000000981:diagnostic imaging*; D013789:Thalassemia / Q000150:complications / Q000000981:diagnostic imaging*