title: Acute diuretic effects in conscious rats produced by some medicinal plants used in the state of São Paulo, Brasil.
abstract: Extracts of 32 medicinal plants used popularly for their presumed diuretic and/or antihypertensive properties were tested for diuretic effects in conscious unrestrained rats. Extracts were made using aqueous ethanol (50:50, v/v) at 4-10 degrees C. When given orally at a dose of 40 ml/kg, a majority of the ethanol-free extracts produced a more pronounced diuresis than would be expected from the potassium concentration of the extracts. The most significant diuretic effect was observed with Hedychium coronarium sheath and leaf-blade extracts.
authors.affiliation: Depto. de Farmacologia, Escola Paulista de Medicina, São Paulo, Brasil.
authors.forename: R de A
authors.initials: Rde A
authors.lastname: Ribeiro
authors.forename: F
authors.initials: F
authors.lastname: de Barros
authors.forename: M M
authors.initials: MM
authors.lastname: de Melo
authors.forename: C
authors.initials: C
authors.lastname: Muniz
authors.forename: S
authors.initials: S
authors.lastname: Chieia
authors.forename: G
authors.initials: G
authors.lastname: Wanderley M das
authors.forename: C
authors.initials: C
authors.lastname: Gomes
authors.forename: G
authors.initials: G
authors.lastname: Trolin
mesh_terms: D000818:Animals; D001938:Brazil; D004231:Diuresis / Q000187:drug effects; D004232:Diuretics / Q000302:isolation & purification*; D004353:Drug Evaluation, Preclinical; D005260:Female; D006863:Hydrogen-Ion Concentration; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000032:analysis; D011188:Potassium / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
chemical_list: D004232:Diuretics; D010936:Plant Extracts; D011188:Potassium