The thieno-triazolodiazepine WEB 2086 inhibits platelet aggregation and ATP release from porcine platelets induced by platelet activating factor (PAF).
Griffin
K J
KJ
Pharmacology Laboratories, Pacific Presbyterian Medical Center/MRI, San Francisco, CA 94115.
Levy
J V
JV
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D001381:Azepines / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D013552:Swine; D014227:Triazines / Q000494:pharmacology*; D014230:Triazoles
D001381:Azepines; D010972:Platelet Activating Factor; D010975:Platelet Aggregation Inhibitors; D014227:Triazines; D014230:Triazoles; C052518:WEB 2086; D000255:Adenosine Triphosphate