title: Efficacy of febantel paste against naturally acquired gastrointestinal nematodes of cattle.
abstract: Twenty calves with naturally acquired gastrointestinal nematode infections were assigned to 10 replicates of 2 calves each and were treated with febantel paste (5 mg/kg of body weight, PO) or an equivalent volume of paste vehicle (control calves). Adverse reactions were not observed after febantel treatment. At necropsy, gastrointestinal nematode counts in febantel-treated calves, compared with control calves, were reduced by over 99% for all major species except Trichuris discolor, counts of which were reduced by only 69%. Counts of gastrointestinal nematode eggs in feces of febantel-treated calves were reduced by 100% after treatment.
authors.affiliation: Department of Infectious Diseases, College of Veterinary Medicine, University of Florida, Gainesville 32610.
authors.forename: C H
authors.initials: CH
authors.lastname: Courtney
authors.forename: J K
authors.initials: JK
authors.lastname: Shearer
authors.forename: Q Y
authors.initials: QY
authors.lastname: Zeng
authors.forename: R G
authors.initials: RG
authors.lastname: Arther
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy* / Q000469:parasitology; D004341:Drug Evaluation / Q000662:veterinary; D005243:Feces / Q000469:parasitology; D005767:Gastrointestinal Diseases / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D006146:Guanidines / Q000008:administration & dosage / Q000627:therapeutic use*; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D009824:Ointments; D010270:Parasite Egg Count / Q000662:veterinary
chemical_list: D000871:Anthelmintics; D006146:Guanidines; D009824:Ointments; C017309:febantel