Coumarin skin necrosis in a patient with heparin-induced thrombocytopenia--a case report.
A patient with evidence of both heparin-related thrombocytopenia and coumarin-induced skin necrosis is presented. Etiology, diagnostic evaluation, histopathology, and therapeutic options are discussed.
Celoria
G M
GM
Department of Surgery, Baystate Medical Center, Springfield, Massachusetts.
Steingart
R H
RH
Banson
B
B
Friedmann
P
P
Rhee
S W
SW
Berman
J A
JA
D001011:Aorta / Q000601:surgery; D001013:Aorta, Thoracic; D003374:Coumarins / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery; D008875:Middle Aged; D009336:Necrosis / Q000139:chemically induced*; D012867:Skin / Q000473:pathology*; D013921:Thrombocytopenia / Q000139:chemically induced*
D003374:Coumarins; D006493:Heparin; C030123:coumarin