Lipo- and apolipoproteins in a population survey subset in MONICA-Israel.
Lipo- and apolipoproteins in a population survey subset in MONICA-Israel. A group of 169 healthy men and women selected at random from the population survey of the MONICA-Israel Project were screened for baseline values of serum lipoproteins and apolipoprotein A-I and B concentrations. The apolipoprotein measurements were obtained using a recently developed immunoturbidimetric assay. The study population was subdivided into age groups of 25-44 years and 45-64 years. It was found that women aged 45-64 years had significantly higher levels of apolipoprotein A-I, apolipoprotein B, total cholesterol (TC), LDL cholesterol (LDL-c) and a lower ratio of HDL-cholesterol (HDL-c) to TC (HDL-c%) than did their younger counterparts. These parameters did not differ significantly between younger and older men. The results suggest that the HDL of women over the age of 45 years contains relatively less cholesterol and more protein than the HDL of younger women. Further studies will show to what degree apolipoprotein concentrations, and their relation to lipoproteins will sharpen the assessment of coronary risk.
Brunner
D
D
Institute of Physiological Hygiene, Faculty of Medicine, Tel Aviv University, Israel.
Slutzky
G M
GM
Weisbort
J
J
Schwartz
S
S
Lingel
R
R
D000328:Adult; D001053:Apolipoproteins / Q000097:blood*; D001054:Apolipoproteins A / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D005260:Female; D006801:Humans; D007557:Israel; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry; D011159:Population Surveillance
D001053:Apolipoproteins; D001054:Apolipoproteins A; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008074:Lipoproteins; D002784:Cholesterol