Amplification of the c-myc proto-oncogene in cervical carcinoma.
Amplification without structural rearrangements of the c-myc proto-oncogene was found in 14 of 44 primary cervical neoplasms. There was no apparent correlation with stage of disease or degree of cellular differentiation. The prognostic significance of c-myc amplification cannot be determined from this study.
Baker
V V
VV
Division of Gynecologic Oncology, University of Alabama, Birmingham.
Hatch
K D
KD
Shingleton
H M
HM
D000230:Adenocarcinoma / Q000235:genetics / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D005784:Gene Amplification; D006801:Humans; D008970:Molecular Weight; D009367:Neoplasm Staging; D000090063:Proto-Oncogene Mas; D011519:Proto-Oncogenes; D012306:Risk; D002583:Uterine Cervical Neoplasms / Q000235:genetics* / Q000473:pathology
D004273:DNA, Neoplasm; C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas