title: Human maximization test of falcarinol, the principal contact allergen of English ivy and Algerian ivy (Hedera helix, H. canariensis).
abstract: In a human maximization test of 5% falcarinol isolated from Hedera helix, 10 of 20 subjects were sensitized. No subjects gave irritant reactions to 5%, 10 became sensitive to 1%, and 7 to 0.05%, with 3 of these giving 3+ to 4+ bullous reactions.
authors.affiliation: Department of Developmental and Cell Biology, University of California, Irvine 92717.
authors.forename: F
authors.initials: F
authors.lastname: Gafner
authors.forename: W
authors.initials: W
authors.lastname: Epstein
authors.forename: G
authors.initials: G
authors.lastname: Reynolds
authors.forename: E
authors.initials: E
authors.lastname: Rodriguez
mesh_terms: D000480:Alkynes; D000485:Allergens; D000818:Animals; D003877:Dermatitis, Contact / Q000209:etiology*; D053280:Diynes; D005233:Fatty Alcohols / Q000633:toxicity*; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D010328:Patch Tests; D010944:Plants / Q000276:immunology*
chemical_list: D000480:Alkynes; D000485:Allergens; D053280:Diynes; D005233:Fatty Alcohols; C018541:falcarinol