title: [Infection with hepatitis B virus in the children and husbands of mothers who are chronic carriers of HbsAg].
abstract: Among relatives of parturients of Majorca island a statistically higher prevalence of HBV markers was found among children (22.8%) and husbands (43.8%) of 49 HBsAg chronic carriers as compared to 2.7% and 19.2%, respectively, among the corresponding relatives of 79 susceptible controls. Prevalence of the carrier state was 0% among both children and husbands of susceptible women, 2.1% (NS) and 11.4% (p less than 0.0001) among husbands and children, respectively, of chronic carrier parturients with a proportion of chronic antigenemia among subjects with HBV markers, that reaches 50% in children and only 4.8% (p less than 0.01) in adults. Following active-passive immunization, an active response of anti-HBs (3.4%), and HBsAg (1.7%), was achieved, after 12 months of follow-up, in 59 newborns of chronic carrier parturients. Detection of HBsAg prior to delivery as well as immunization both of newborns and susceptible household contacts of chronic carrier mothers should become general.
authors.affiliation: Centro Materno-Infantil, Hospital Virgen del Lluch, Palma de Mallorca.
authors.forename: M L
authors.initials: ML
authors.lastname: González González
authors.forename: C
authors.initials: C
authors.lastname: Serra Mas
authors.forename: A
authors.initials: A
authors.lastname: Roses Pou
authors.forename: A
authors.initials: A
authors.lastname: Garau Barceló
authors.forename: P
authors.initials: P
authors.lastname: Ferrer de San Jordi
authors.forename: M
authors.initials: M
authors.lastname: Maimo Vaquer
authors.forename: P
authors.initials: P
authors.lastname: Alomar Cardell
authors.forename: R
authors.initials: R
authors.lastname: Llinares Macía
authors.forename: I
authors.initials: I
authors.lastname: Blanco González
authors.forename: J M
authors.initials: JM
authors.lastname: del Valle Millán
mesh_terms: D000328:Adult; D002353:Carrier State; D002648:Child; D002675:Child, Preschool; D005260:Female; D006509:Hepatitis B / Q000635:transmission*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D049590:Postpartum Period / Q000276:immunology*; D011247:Pregnancy; D013030:Spain
chemical_list: D006514:Hepatitis B Surface Antigens
vernacular_title: Infección por virus de la hepatitis B en hijos y cónyuges de madres portadoras crónicas del HBsAg.