title: Activities of compound G2 isolated from alfalfa roots against dermatophytes.
abstract: An antimycotic agent, compound G2, isolated from alfalfa roots exhibited considerable activity against the six most common dermatophytes. MICs in agar and broth dilutions ranged from 10 to 30 micrograms/ml and from 2 to 10 micrograms/ml, respectively. G2 was fungicidal at 5 to 22 micrograms/ml. Structure and toxicity relations are discussed.
authors.affiliation: Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Evron
authors.forename: I
authors.initials: I
authors.lastname: Polacheck
authors.forename: M
authors.initials: M
authors.lastname: Guizie
authors.forename: M
authors.initials: M
authors.lastname: Levy
authors.forename: U
authors.initials: U
authors.lastname: Zehavi
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D004821:Epidermophyton / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects*; D014249:Trichophyton / Q000187:drug effects*; D014315:Triterpenes / Q000494:pharmacology*
chemical_list: D000935:Antifungal Agents; D014315:Triterpenes; C049077:medicagenic acid-3-O-glucopyranoside