[Evaluation of the level and radiosensitivity of the hematopoietic stem cell pool in man by the number of endocolonies of undifferentiated cells forming against a background of post-radiation bone marrow aplasia].
The value and radiosensitivity of human haemopoietic stem pool may be assessed by the number of colonies of nondifferentiated cells (CFUnc) formed in situ during regeneration of the haemopoietic organ from the postirradiation aplasia. The time required for doubling the population, that constitutes nondifferentiated cell endocolonies, was reduced as the radiation dose increased.
Suvorova
L A
LA
Gruzdev
G P
GP
D001853:Bone Marrow / Q000473:pathology* / Q000528:radiation effects; D002452:Cell Count; D002454:Cell Differentiation; D003114:Colony-Forming Units Assay; D006412:Hematopoietic Stem Cells / Q000528:radiation effects*; D006801:Humans; D011832:Radiation Injuries / Q000473:pathology*; D011836:Radiation Tolerance
Otsenka urovnia i radiochuvstvitel'nosti stvolovogo krovetvornogo pula cheloveka po chislu éndokoloniĭ nedifferentsirovannykh kletok, formiruiushchikhsia na fone postluchevoĭ aplazii kostnogo mozga.