title: Evaluation of intravesical alum irrigation for massive bladder hemorrhage.
abstract: The efficacy of intravesical alum irrigation was analyzed after application to 9 patients with continuous and severe bladder hemorrhage. Causes of bleeding were radiation cystitis in 4 patients, vesical invasion by cervical cancer in 3, bladder cancer in 1 and cyclophosphamide-induced cystitis in 1. Though alum treatment was initially effective for control of massive bladder hemorrhage in all patients, it eventually failed to suppress a subsequent hemorrhage in 2 patients (78% success rate). No significant side effects directly related to this therapy were observed. In conclusion, alum irrigation is effective for controlling massive bladder hemorrhage for a rather short time. Therefore, additional treatment modalities should also be considered for primary diseases.
authors.affiliation: Department of Urology, Nagoya University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Takashi
authors.forename: A
authors.initials: A
authors.lastname: Kondo
authors.forename: K
authors.initials: K
authors.lastname: Kato
authors.forename: T
authors.initials: T
authors.lastname: Murase
authors.forename: K
authors.initials: K
authors.lastname: Miyake
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D000534:Alum Compounds; D000535:Aluminum / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013431:Sulfates / Q000008:administration & dosage* / Q000627:therapeutic use; D007507:Therapeutic Irrigation; D001745:Urinary Bladder Diseases / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000534:Alum Compounds; D013431:Sulfates; C041524:aluminum sulfate; D000535:Aluminum