Protein gradients in the cerebrospinal fluid and the calculation of intracerebral IgG synthesis.
When six successive samples of 2.5 ml cerebrospinal fluid (CSF) were withdrawn from eight multiple sclerosis (MS) and 12 other neurological disease (OND) patients, the IgG index rose continuously between 2.9 and 24.0%, while both the Tourtellotte as well as the Reiber/Felgenhauer formulas were less affected.
Wurster
U
U
Division of Neurology/Neurophysiology, Medical School, Hannover, F.R.G.
D001921:Brain / Q000378:metabolism*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis* / Q000134:cerebrospinal fluid; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid* / Q000378:metabolism; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid* / Q000378:metabolism*; D012709:Serum Albumin / Q000134:cerebrospinal fluid / Q000378:metabolism*
D007074:Immunoglobulin G; D012709:Serum Albumin