title: Spinal epidural compression secondary to osteoblastic metastatic vertebral expansion.
abstract: We present two cases in which spinal epidural compression was caused by the expansion of bony elements into the spinal canal as a result of osteoblastic metastases. The precise nature of the compression was appreciated only on computed tomography. One patient had immediate and sustained neurological improvement after laminectomy. The other benefited temporarily, but widespread involvement of his spine ultimately led to paraplegia despite two more decompressive procedures. We think that bony expansion of the spine secondary to osteoblastic metastasis is not reversible with radiation therapy alone and is, therefore, an absolute indication for surgical decompression.
authors.affiliation: Department of Neurosurgery, Albert Einstein College of Medicine, Bronx, New York.
authors.forename: A
authors.initials: A
authors.lastname: Hirschfeld
authors.forename: W
authors.initials: W
authors.lastname: Beutler
authors.forename: J
authors.initials: J
authors.lastname: Seigle
authors.forename: H
authors.initials: H
authors.lastname: Manz
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms; D002277:Carcinoma / Q000150:complications / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D007796:Laminectomy; D008297:Male; D011471:Prostatic Neoplasms; D011859:Radiography; D013117:Spinal Cord Compression / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D013125:Spinal Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary*