title: [Treatment of experimental destruction of the duodenum with preparations with nootropic action].
abstract: In the experiments on rats the peptic ulcer of duodenum was simulated by means of mechanic compression of reflexogenic zones of pylorus and intestine. The destruction of duodenal mucosa was developed in 3-4 hours after the compression and retained in the course of 5-6 days. Piracetam (200 mg/kg) and etimizol (3 mg/kg) eliminated and cimetidine (25 mg/kg), solcoseryl (0.5 mg/kg) and metacine (5 mg/kg) diminished the destruction after the course of 6 injections of each drug with an interval of 10-12 hours. Therapeutic effects of piracetam and etimizol correlated with their ability to return towards normal concentration of creatine phosphate.
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Buliusin
authors.forename: T N
authors.initials: TN
authors.lastname: Nilova
authors.forename: P D
authors.initials: PD
authors.lastname: Shabanov
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000378:metabolism; D004386:Duodenum / Q000187:drug effects / Q000378:metabolism; D004734:Energy Metabolism / Q000187:drug effects; D008297:Male; D010725:Phosphocreatine / Q000378:metabolism; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D051381:Rats; D013997:Time Factors
chemical_list: D011619:Psychotropic Drugs; D010725:Phosphocreatine
vernacular_title: Lechenie éksperimental'nykh destruktsiĭ dvenadtsatiperstnoĭ kishki preparatami nootropnogo deĭstviia.