title: Hypospadias repair by bladder mucosal graft: an initial report.
abstract: Surgical correction of major hypospadias defects is a challenging problem. Bladder mucosa has been reported as an excellent tissue for construction of a neourethra. We used bladder mucosa in 13 boys to create 15 neourethras when there was inadequate preputial skin to perform a vascularized pedicle flap or a free preputial graft. In 3 cases a bladder mucosa graft was used for initial repair of the hypospadias. All other boys had undergone prior hypospadias surgery. In 4 boys the initial result was satisfactory. Seven minor complications occurred in 5 boys, while 4 had more major complications. In 2 boys severe problems with stricture necessitated graft replacement and a satisfactory outcome has not been achieved. Our problems with stricture and stenosis seem to be related to the use of a subcutaneous tunnel for the graft bed and coring of the glans to create the meatus. Over-all, in 11 of the 13 boys the bladder mucosal graft provided an excellent resolution of the complex problem with easily managed postoperative complications.
authors.affiliation: Scott Department of Urology, Baylor College of Medicine, Houston, Texas.
authors.forename: R M
authors.initials: RM
authors.lastname: Decter
authors.forename: D R
authors.initials: DR
authors.lastname: Roth
authors.forename: E T
authors.initials: ET
authors.lastname: Gonzales
mesh_terms: D002648:Child; D002675:Child, Preschool; D003251:Constriction, Pathologic; D004106:Dilatation; D006801:Humans; D007021:Hypospadias / Q000628:therapy*; D007223:Infant; D008297:Male; D009092:Mucous Membrane / Q000637:transplantation; D011183:Postoperative Complications; D012086:Reoperation; D014521:Urethra / Q000601:surgery; D001743:Urinary Bladder / Q000637:transplantation*