Evaluation of a rotating filter for use with therapeutic plasma exchange.
A rotating filter system was evaluated for therapeutic plasma exchange. In vitro and in vivo studies revealed sieving coefficients of clinically important molecules to be essentially 1, with no substantial decline over time. A modification of the tubing system allowed for continuous flow, double access operation. Placing the collection bag at the base of the machine provided excellent plasma removal rates with only minimal blood flows. A rotating filter can provide a highly efficient system for therapeutic plasma exchange.
Kaplan
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Division of Nephrology, University of Connecticut Health Center, Farmington, 06032.
Halley
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D000328:Adult; D001798:Blood Proteins / Q000032:analysis; D005069:Evaluation Studies as Topic; D005260:Female; D005374:Filtration / Q000295:instrumentation; D006801:Humans; D066298:In Vitro Techniques; D008074:Lipoproteins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange / Q000295:instrumentation*; D012712:Serum Globulins / Q000032:analysis
D001798:Blood Proteins; D008074:Lipoproteins; D012712:Serum Globulins