The Ionescu-Shiley pericardial valve: results in 473 patients.
From January 1, 1980, through December 31, 1985, 473 patients underwent valve replacement with an Ionescu-Shiley valve. Overall hospital mortality was 7.8%. Major associated procedures and preoperative New York Heart Association (NYHA) Classes IV and V influenced hospital mortality significantly. The mean follow-up was 2.6 +/- 1.3 years. Late mortality was 5.9%. Overall actuarial survival was 81% at 5 years. A chief cause of reoperation was cusp rupture of a mitral prosthesis in 5 patients (all after aortic and mitral valve replacement). The overall actuarial reoperation-free incidence was 93% at 5 years. Thromboembolic (TB) phenomena occurred at a linear incidence of 1.4 +/- 0.3% per patient-year or an actuarial thromboembolism-free incidence of 92% at 5 years. Univariate and multivariate analyses showed that postoperative NYHA Class, rhythm at follow-up, and anticoagulant therapy significantly influenced the incidence of TE phenomena.
Daenen
W
W
Department of Cardiovascular Surgery, University Hospital Gasthuisberg, Leuven, Belgium.
Noyez
L
L
Lesaffre
E
E
Goffin
Y
Y
Stalpaert
G
G
D000368:Aged; D001021:Aortic Valve; D001705:Bioprosthesis / Q000401:mortality; D005260:Female; D006350:Heart Valve Prosthesis / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D011183:Postoperative Complications; D011475:Prosthesis Failure; D013923:Thromboembolism / Q000209:etiology; D014261:Tricuspid Valve