title: Partial amino acid sequence analysis of human placenta monoamine oxidase A and bovine liver monoamine oxidase B.
abstract: We have prepared peptide maps from human placenta monoamine oxidase type A (MAO-A) and bovine monoamine oxidase type B (MAO-B) and determined the amino acid sequences of 21 of these peptides. These sequences have been compared to the cDNA deduced amino acid sequences of human MAO-A and -B. A result of special interest is the identification of two sets of MAO-A peptides which have sequences different from those deduced from cDNA sequences. This observation is consistent with the notion that MAO-A may be composed of at two subunits which are similar but not identical in primary amino acid sequence.
authors.affiliation: Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010.
authors.forename: S A
authors.initials: SA
authors.lastname: Chen
authors.forename: W
authors.initials: W
authors.lastname: Weyler
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000302:isolation & purification; D008930:Mitochondria, Liver / Q000201:enzymology*; D008969:Molecular Sequence Data; D008995:Monoamine Oxidase / Q000302:isolation & purification; D010446:Peptide Fragments / Q000032:analysis; D010449:Peptide Mapping; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D013045:Species Specificity; D014357:Trypsin
chemical_list: D007527:Isoenzymes; D010446:Peptide Fragments; D008995:Monoamine Oxidase; D014357:Trypsin