The use of folding patterns in the search of protein structural similarities; a three-dimensional model of phosphoribosyl transferases.
A new way to predict the topologies of proteins of unknown three-dimensional structure is derived from the comparison of the distribution of the strongest predicted secondary structures with equivalent distributions recorded for proteins of known X-ray structures. As an illustration the tentative three-dimensional model of phosphoribosyl transferases which was proposed by Argos et al. is rediscussed.
Busetta
B
B
Laboratoire de Cristallographie U.A 144, Talence, France.
D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D006801:Humans; D006860:Hydrogen Bonding; D008969:Molecular Sequence Data; D010430:Pentosyltransferases; D011487:Protein Conformation; D013329:Structure-Activity Relationship; D014961:X-Ray Diffraction
D010430:Pentosyltransferases