title: [Midazolam in combination with piritramid versus Thalamonal in premedication in ambulatory ENT interventions in childhood].
abstract: 70 children aged between 15 months and 8 years who had to undergo outpatient surgery (adenotomy) were divided into two groups and given different premedication. Group A received Midazolam (0.15 mg/kg) combined with Piritramid (0.1 mg/kg), group B Thalamonal (0.04 ml/kg). Based on vigilance schemes, the degree of sedation and the mood tone were rated during initiation of anaesthesia, in the awakening phase and on discharge of the patient. Cooperation during initiation (via a mask) was definitely higher in group A (72%) than in group B (44%). During the awakening phase the children in group A showed a more balanced mood tone combined with improved vigilance. For example, 3 hours postoperatively 65% of the children in group A had got up and participated in getting dressed, whereas in group B only 11% of the children did so. Intramuscular premedication with Midazolam/Piritramid must be considered as especially advantageous in outpatient ENT treatment requiring a large number of small surgical interventions in children in respect of effective preparation and with a minimum of problems regarding postoperative follow-up.
authors.affiliation: Institut für Anästhesiologie der Ludwig-Maximilians-Universität München.
authors.forename: T
authors.initials: T
authors.lastname: Bein
authors.forename: H
authors.initials: H
authors.lastname: Tremel
authors.forename: G
authors.initials: G
authors.lastname: Heyde
mesh_terms: D000233:Adenoidectomy; D000556:Ambulatory Surgical Procedures; D000768:Anesthesia, General; D001143:Arousal / Q000187:drug effects; D002675:Child, Preschool; D004329:Droperidol / Q000008:administration & dosage*; D004338:Drug Combinations / Q000008:administration & dosage; D005283:Fentanyl / Q000008:administration & dosage*; D006801:Humans; D007540:Isonipecotic Acids / Q000008:administration & dosage*; D008874:Midazolam / Q000008:administration & dosage*; D008876:Middle Ear Ventilation; D010892:Pirinitramide / Q000008:administration & dosage*; D011229:Preanesthetic Medication
chemical_list: D004338:Drug Combinations; D007540:Isonipecotic Acids; D010892:Pirinitramide; C001451:Innovar; D004329:Droperidol; D008874:Midazolam; D005283:Fentanyl
vernacular_title: Midazolam in Kombination mit Piritramid versus Thalamonal zur Prämedikation beim ambulanten HNO-Eingriff im Kindesalter.