[Prevention using ascorbic acid, hexamethylenetetramine and sodium metabisulfite of the blastomogenic effect caused by the combined administration into the stomach of mice of sodium nitrite with methylurea or with aminopyrine].
It was shown in experiments on 186 mice that formation of tumors of the lung and fore-stomach induced by injection of sodium nitrite in combination with aminopyrine or methylurea is inhibited following treatment with ascorbic acid, hexamethylenetetramine or sodium metabisulfite.
Dzhioev
F K
FK
D000632:Aminopyrine / Q000008:administration & dosage*; D000818:Animals; D001205:Ascorbic Acid / Q000627:therapeutic use*; D003043:Cocarcinogenesis; D005260:Female; D008175:Lung Neoplasms / Q000139:chemically induced* / Q000517:prevention & control; D008297:Male; D008709:Methenamine / Q000627:therapeutic use*; D008782:Methylurea Compounds / Q000008:administration & dosage*; D051379:Mice; D008815:Mice, Inbred Strains; D009573:Nitrites / Q000008:administration & dosage*; D012977:Sodium Nitrite / Q000008:administration & dosage*; D013274:Stomach Neoplasms / Q000139:chemically induced* / Q000517:prevention & control; D013447:Sulfites / Q000627:therapeutic use*
D008782:Methylurea Compounds; D009573:Nitrites; D013447:Sulfites; D000632:Aminopyrine; C005200:sodium metabisulfite; D008709:Methenamine; D012977:Sodium Nitrite; D001205:Ascorbic Acid; C002352:methylurea
Preduprezhdenie s pomoshch'iu askorbinovoĭ kisloty, geksametilentetramina i metabisul'fita natriia blastomogennogo éffekta, vyzvannogo sovmestnym vvedeniem v zheludok mysham nitrita natriia s metilmochevinoĭ ili s amidopirinom.