title: Surgical management of doubly committed subarterial ventricular septal defects.
abstract: The clinical presentation, diagnosis, and surgical treatment of 63 patients with doubly committed subarterial ventricular septal defects (DCVSD) were analyzed retrospectively. The patients were divided into three groups. Thirty-one patients had severe congestive heart failure in infancy and presently have a large ventricular septal defect that has no tendency to close or to produce aortic valve regurgitation (Group 1). Ideally, these defects should be closed in infancy, and the transpulmonary approach is recommended to achieve closure. In the first group, there was one death in a patient with a hypoplastic right ventricle. In Group 2, nineteen patients had aortic valve prolapse or aortic valve regurgitation. The DCVSD were moderately large or small. A number of DCVSD in Group 2 patients had maintained the normal offsetting of the arterial valves. These defects must be closed by the time mild aortic valve regurgitation has occurred. In Group 2, there was one late death in a patient who developed subacute bacterial endocarditis. The two patients who had severe aortic valve regurgitation required aortic valve replacement and underwent multiple surgical procedures to replace calcified bioprostheses. Group 3 comprised 13 patients who were diagnosed with tetralogy of Fallot. All of these patients had a large DCVSD with aortic valve overriding. All Group 3 patients survived radical repair of the defect, which required a transannular patch in most cases (76%).
authors.affiliation: Hospital for Sick Children, London, England.
authors.forename: M R
authors.initials: MR
authors.lastname: de Leval
authors.forename: M
authors.initials: M
authors.lastname: Pozzi
authors.forename: V
authors.initials: V
authors.lastname: Starnes
authors.forename: I D
authors.initials: ID
authors.lastname: Sullivan
authors.forename: J
authors.initials: J
authors.lastname: Stark
authors.forename: J
authors.initials: J
authors.lastname: Somerville
authors.forename: R H
authors.initials: RH
authors.lastname: Anderson
authors.forename: J E
authors.initials: JE
authors.lastname: Deanfield
mesh_terms: D000293:Adolescent; D001021:Aortic Valve / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D006333:Heart Failure / Q000150:complications; D006345:Heart Septal Defects, Ventricular / Q000150:complications / Q000601:surgery*; D006349:Heart Valve Diseases / Q000150:complications / Q000601:surgery; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D007223:Infant