Experimental chemotherapy in horses infected with benzimidazole-resistant small strongyles.
The presence of benzimidazole-resistant strains of equine small strongyles was confirmed in horses at two properties in north west England by a series of faecal egg counts and larval cultures after treatment with mebendazole. A trail formulation of mebendazole in combination with piperazine citrate gave greater reductions in faecal egg counts than mebendazole alone but was much less effective than pyrantel embonate or dichlorvos.
Britt
D P
DP
Faculty of Allied Health Sciences and Nursing, Sulaibikhat, Kuwait.
Clarkson
M J
MJ
D000818:Animals; D004006:Dichlorvos / Q000627:therapeutic use; D004338:Drug Combinations; D004341:Drug Evaluation; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D005260:Female; D006736:Horses; D007814:Larva / Q000302:isolation & purification; D008297:Male; D008463:Mebendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D010270:Parasite Egg Count / Q000662:veterinary; D010879:Piperazines / Q000008:administration & dosage / Q000627:therapeutic use; D011716:Pyrantel Pamoate / Q000627:therapeutic use; D013319:Strongyle Infections, Equine / Q000188:drug therapy* / Q000469:parasitology; D013323:Strongylus / Q000187:drug effects
D004338:Drug Combinations; D010879:Piperazines; C006589:piperazine citrate; D004006:Dichlorvos; D011716:Pyrantel Pamoate; D008463:Mebendazole