title: Topographic, non-collateralized basal forebrain projections to amygdala, hippocampus, and anterior cingulate cortex in the rhesus monkey.
abstract: Projections of the basal forebrain magnocellular complex to the limbic telencephalon of the primate were studied by combining double-retrograde tracing with immunocytochemistry. Tracers were injected into anterior cingulate cortex and hippocampus or into hippocampus and amygdala. Retrogradely labeled populations of neurons were topographically arranged but intermingled peripherally. Double-labeled neurons, found only after amygdala-hippocampus injections, were very rare. Approximately 30% of hippocampopetal, 50-70% of amygdalopetal, and 50-90% of cingulopetal neurons were cholinergic; percentages varied among different regions of basal forebrain. These findings further support the concept of a system with a highly organized efferent circuitry.
authors.affiliation: Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205-2182.
authors.forename: V E
authors.initials: VE
authors.lastname: Koliatsos
authors.forename: L J
authors.initials: LJ
authors.lastname: Martin
authors.forename: L C
authors.initials: LC
authors.lastname: Walker
authors.forename: R T
authors.initials: RT
authors.lastname: Richardson
authors.forename: M R
authors.initials: MR
authors.lastname: DeLong
authors.forename: D L
authors.initials: DL
authors.lastname: Price
mesh_terms: D000578:Amidines; D000679:Amygdala / Q000033:anatomy & histology*; D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology*; D001931:Brain Mapping; D005456:Fluorescent Dyes; D006179:Gyrus Cinguli / Q000033:anatomy & histology*; D006624:Hippocampus / Q000033:anatomy & histology*; D008251:Macaca / Q000033:anatomy & histology*; D008253:Macaca mulatta / Q000033:anatomy & histology*; D009434:Neural Pathways / Q000033:anatomy & histology
chemical_list: D000578:Amidines; D005456:Fluorescent Dyes; C031455:diamidino compound 253-50; C037945:diamidino yellow