[Effect of hydrogen peroxide on the permeability of the walls of the mesenteric venules for fluorescein].
An algorithm of the fluorescent microscopy data analysis enabled to assess the coefficient of the diffusion permeability of the microvessels' walls for substances with small molecular mass (sodium fluorescent). A short-term application of hydrogen peroxide increased relative values of the coefficient. The effect of the oxygen free radicals on the permeability seems to be associated with structural disorder of the glycocalix in intercellular contacts of the microvessels' endothelium.
Banin
V V
VV
Müller
F S
FS
D000465:Algorithms; D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects*; D004058:Diffusion; D019793:Fluorescein; D005452:Fluoresceins; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D008433:Mathematics; D008643:Mesentery / Q000098:blood supply*; D008856:Microscopy, Fluorescence / Q000379:methods; D051381:Rats; D014699:Venules / Q000187:drug effects
D005452:Fluoresceins; D006861:Hydrogen Peroxide; D019793:Fluorescein
Vliianie perekisi vodoroda na pronitsaemost' stenok venul bryzheĭki dlia fliuorestseina.