title: [Electrocardiographic findings in pulmonary arterial hypertension in children].
abstract: Pulmonary hypertension (PH) induces high risk of cardiovascular morbidity and mortality, mainly in the primary or essential type. Invasive studies are needed to confirm the diagnosis; among the non- invasive approach, the electrocardiogram has been used to suspect such entity with poor results due to inadequate diagnostic criteria. Twelve children with pulmonary hypertension of the essential type (PPH) and ten children with PH due to interventricular septal defect (VSD) were studied haemodynamically and electrocardiographically and compared to electrocardiographic data of 53 normal children. PPH showed higher resistances than VSD (17.2 +/- 1.9 vs 6 +/- 0.6 u/m2 p less than 0.01) with the same pressure level (99.5 +/- 10.3 vs 101.5 +/- 4.8 mmHg). Right axis deviation, peaked P wave, increased ventricular activation time and prominent ST-T changes were seen in PPH patients whereas in VSD the electrical axis was within normal limits, without P wave changes and in some cases, less conspicuous ST-T abnormalities were observed (p less than 0.01). Such changes showed good sensitivity (80%) and specificity (81%) to suspect PH with resistances higher than 10 u/m2 with a predictive value of 75% (p less than 0.02). P wave and ST-T changes could be of use to suspect PPH with elevated resistances instead of right ventricular hypertrophy voltage criteria.
authors.affiliation: Instituto Nacional de Cardiología Ignacio Chávez, México, D.F.
authors.forename: J A
authors.initials: JA
authors.lastname: Marín
authors.forename: A
authors.initials: A
authors.lastname: Buendía
authors.forename: D
authors.initials: D
authors.lastname: Zavaleta
mesh_terms: D002648:Child; D004562:Electrocardiography; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000150:complications*; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000503:physiopathology*; D008297:Male
vernacular_title: Hallazgos electrocardiográficos en la hipertensión arterial pulmonar en niños.