title: [A mechanism of inhibition of fibrin self-assembly by a peptide inhibitor].
abstract: The amino acid composition of fibrin self-assembly inhibitors isolated from the blood plasma of man, ox, albino rat and from frog muscle tissue was established. Using a human blood plasma inhibitor, it was found that the inhibition of fibrin self-assembly is due to the inhibitor interaction with monomeric fibrin in the sites of domain D which become accessible after fibrinogen activation by thrombin.
authors.lastname: Chiriat'evEA
authors.forename: O P
authors.initials: OP
authors.lastname: Leonova
authors.forename: A Sh
authors.initials: ASh
authors.lastname: Byshevskiĭ
mesh_terms: D000818:Animals; D002417:Cattle; D002850:Chromatography, Gel; D005337:Fibrin / Q000037:antagonists & inhibitors*; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D007700:Kinetics; D010455:Peptides; D013917:Thrombin
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; D010455:Peptides; C036309:fibrin fragment D; D005337:Fibrin; C052940:fibrin self-assembly inhibitor; D013917:Thrombin
vernacular_title: Mekhanizm tormozheniia samosborki fibrina ingibitorom peptidnoĭ prirody.