title: [Comparative study of the progestagenic action of 16 alpha, 17 alpha-cyclohexanoprogesterones (pregna-D'6-pentarans) when administered by different routes].
abstract: A comparative study of the progestational activity of modified pentarans depending on the dose and the route of administration was carried out. It was shown that modification of the molecule of 16 alpha, 17 alpha-cyclohexanoprogesterones by introducing and additional double bond in positions 6, 7 and methyl group in position 6 provided a high gestational effect, being particularly pronounced at intramuscular administration.
authors.forename: G V
authors.initials: GV
authors.lastname: Nikitina
authors.forename: V V
authors.initials: VV
authors.lastname: Korkhov
authors.forename: L E
authors.initials: LE
authors.lastname: Kulikova
authors.forename: I S
authors.initials: IS
authors.lastname: Levina
authors.forename: A V
authors.initials: AV
authors.lastname: Kamernitskiĭ
mesh_terms: D000284:Administration, Oral; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004717:Endometrium / Q000187:drug effects / Q000378:metabolism; D005260:Female; D007273:Injections, Intramuscular; D009644:Norgestrel / Q000494:pharmacology; D011374:Progesterone / Q000031:analogs & derivatives* / Q000494:pharmacology; D045167:Progesterone Congeners / Q000494:pharmacology*; D011817:Rabbits; D013329:Structure-Activity Relationship
chemical_list: D045167:Progesterone Congeners; D009644:Norgestrel; D011374:Progesterone
vernacular_title: Sravnitel'noe izuchenie progestagennogo deĭstviia 16 al'fa, 17 al'fa-tsiklogeksanoprogesteronov (pregna-D'6-pentaranov) pri razlichnykh putiakh vvedeniia.