Transfusion-related acute lung injury.
Noncardiogenic pulmonary edema after transfusion therapy is an infrequent but hazardous complication. The occurrence of this entity is linked to the presence of circulating leukoagglutinins. The clinical features are described on the basis of four cases. The hemodynamic changes, underlying mechanisms and therapeutic strategies are discussed.
Gans
R O
RO
Department of Medicine, Catharina Hospital Eindhoven, The Netherlands.
Duurkens
V A
VA
van Zundert
A A
AA
Hoorntje
S J
SJ
D000208:Acute Disease; D000328:Adult; D000373:Agglutinins / Q000276:immunology; D000906:Antibodies / Q000032:analysis; D001788:Blood Grouping and Crossmatching; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007962:Leukocytes / Q000276:immunology; D008297:Male; D011506:Proteins; D011654:Pulmonary Edema / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D011859:Radiography; D012129:Respiratory Function Tests; D065227:Transfusion Reaction
D000373:Agglutinins; D000906:Antibodies; D011506:Proteins; C100155:leukoagglutinins, leukocytes; D003907:Dexamethasone