Renal thorium deposition associated with transitional cell carcinoma: radiologic demonstration in two patients.
Abdominal radiography, excretory urography, retrograde pyelography, and computed tomography were performed in two patients who had undergone retrograde pyelography with thorium dioxide (Thorotrast) approximately 40 years ago. Both patients developed a transitional cell carcinoma due to suburothelial thorium deposition. Typical thorium densities were demonstrated at CT in the peripelvicalyceal area as well as in retroperitoneal lymph nodes. Elderly patients in whom radiographic examination reveals retained Thorotrast in the kidney should be followed up because of the high risk of renal carcinoma.
Oyen
R H
RH
Department of Radiology, University Hospitals Catholic University Leuven, Belgium.
Gielen
J L
JL
Van Poppel
H P
HP
Verbeken
E K
EK
Van Damme
B J
BJ
Baert
L V
LV
Baert
A L
AL
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000139:chemically induced / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000000981:diagnostic imaging*; D013911:Thorium Dioxide / Q000009:adverse effects*; D014567:Urography
D013911:Thorium Dioxide