The concurrence of Klinefelter syndrome and fragile X syndrome.
In this paper we report on a third patient with Klinefelter syndrome and fragile X. In the Leuven experience the simultaneous occurrence of both conditions is 1:155 (3 fra(X) positive Klinefelter patients in a total number of 465 fra(X) positive males), a concurrence much higher than expected by chance considering the frequency of both conditions.
Fryns
J P
JP
Center for Human Genetics, University of Leuven, Belgium.
Van den Berghe
H
H
D000328:Adult; D005260:Female; D005600:Fragile X Syndrome / Q000150:complications* / Q000235:genetics; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications* / Q000235:genetics; D008297:Male; D010375:Pedigree; D010641:Phenotype; D012729:Sex Chromosome Aberrations / Q000150:complications*