Production of specific retinal S antigen antibodies in patients with retinal detachment.
One hundred patients with retinal detachment (61 primary operations and 39 reoperations) were studied for titers of autoantibodies to human retinal S antigen using the enzyme-linked immunosorbent assay technique (ELISA). There was no statistically significant difference when comparing the group of patients with primary retinal detachment with the control group. However, a statistically significant increase in anti-S titers was recorded when a comparison was made between the group of reoperated patients and the control group (chi 2, P less than 0.001) and between the group of reoperated subjects and the group of patients operated on for the first time (chi 2, P less than 0.005).
García
H
H
Barraquer Ophthalmology Centre, Barcelona, Spain.
Dante
C
C
Calderon
G
G
Antonio
P
P
D000918:Antibody Specificity; D000941:Antigens / Q000276:immunology*; D019393:Arrestin; D004797:Enzyme-Linked Immunosorbent Assay; D005136:Eye Proteins / Q000276:immunology*; D005260:Female; D006801:Humans; D008297:Male; D012086:Reoperation; D012163:Retinal Detachment / Q000276:immunology* / Q000503:physiopathology / Q000601:surgery; D013223:Statistics as Topic; D013997:Time Factors
D000941:Antigens; D019393:Arrestin; D005136:Eye Proteins