[Infection with hepatitis B virus in the children and husbands of mothers who are chronic carriers of HbsAg].
Among relatives of parturients of Majorca island a statistically higher prevalence of HBV markers was found among children (22.8%) and husbands (43.8%) of 49 HBsAg chronic carriers as compared to 2.7% and 19.2%, respectively, among the corresponding relatives of 79 susceptible controls. Prevalence of the carrier state was 0% among both children and husbands of susceptible women, 2.1% (NS) and 11.4% (p less than 0.0001) among husbands and children, respectively, of chronic carrier parturients with a proportion of chronic antigenemia among subjects with HBV markers, that reaches 50% in children and only 4.8% (p less than 0.01) in adults. Following active-passive immunization, an active response of anti-HBs (3.4%), and HBsAg (1.7%), was achieved, after 12 months of follow-up, in 59 newborns of chronic carrier parturients. Detection of HBsAg prior to delivery as well as immunization both of newborns and susceptible household contacts of chronic carrier mothers should become general.
González González
M L
ML
Centro Materno-Infantil, Hospital Virgen del Lluch, Palma de Mallorca.
Serra Mas
C
C
Roses Pou
A
A
Garau Barceló
A
A
Ferrer de San Jordi
P
P
Maimo Vaquer
M
M
Alomar Cardell
P
P
Llinares Macía
R
R
Blanco González
I
I
del Valle Millán
J M
JM
D000328:Adult; D002353:Carrier State; D002648:Child; D002675:Child, Preschool; D005260:Female; D006509:Hepatitis B / Q000635:transmission*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D049590:Postpartum Period / Q000276:immunology*; D011247:Pregnancy; D013030:Spain
D006514:Hepatitis B Surface Antigens
Infección por virus de la hepatitis B en hijos y cónyuges de madres portadoras crónicas del HBsAg.