Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31----q41.
Polymeric immunoglobulin receptor (PIGR) is a transmembrane glycoprotein which is expressed by epithelial cells and is involved in the transcellular transport of polymeric immunoglobulins into secretions. We cloned the human gene for PIGR and used the clone to obtain probes to determine the chromosomal localization of PIGR. Analysis of somatic cell hybrids and in situ chromosomal hybridization localized the human PIGR gene locus to 1q31----q41.
Davidson
M K
MK
Department of Microbiology and Immunology, University of Illinois, Chicago 60680.
Le Beau
M M
MM
Eddy
R L
RL
Shows
T B
TB
DiPietro
L A
LA
Kingzette
M
M
Hanly
W C
WC
D015139:Blotting, Southern; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D003001:Cloning, Molecular; D006801:Humans; D006822:Hybrid Cells; D008677:Metaphase; D015345:Oligonucleotide Probes; D011971:Receptors, Immunologic / Q000235:genetics*; D015183:Restriction Mapping; D012635:Secretory Component; D012689:Sequence Homology, Nucleic Acid
D015345:Oligonucleotide Probes; D011971:Receptors, Immunologic; D012635:Secretory Component