title: [A clinical evaluation of CS-807 in patients with urinary tract infections].
abstract: CS-807 is a new cephalosporin orally available. The clinical efficacy and safety of this drug were evaluated in 13 patients with urinary tract infection, including 3 with simple cystitis and 10 with complicated infections. According to the response criteria defined by the Japanese UTI committee, the clinical effectiveness in 8 patients with complicated urinary tract infections regarded evaluable was excellent in 2, moderate in 4 and poor in 2, the overall efficacy rate being 75.0%. Only 1 of the 13 patients studied, developed temporary diarrhea as a drug related adverse reaction.
authors.affiliation: Department of Urology, School of Medicine, Kanazawa University.
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: Y
authors.initials: Y
authors.lastname: Oshinoya
authors.forename: T
authors.initials: T
authors.lastname: Uchibayashi
authors.forename: M
authors.initials: M
authors.lastname: Ohkawa
authors.forename: H
authors.initials: H
authors.lastname: Hisazumi
mesh_terms: D000328:Adult; D000368:Aged; D000892:Anti-Infective Agents, Urinary / Q000627:therapeutic use*; D015296:Ceftizoxime / Q000031:analogs & derivatives*; D002511:Cephalosporins / Q000009:adverse effects / Q000627:therapeutic use*; D003556:Cystitis / Q000188:drug therapy; D003967:Diarrhea / Q000139:chemically induced; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014552:Urinary Tract Infections / Q000188:drug therapy*; D000097627:Cefpodoxime Proxetil
chemical_list: D000892:Anti-Infective Agents, Urinary; D015296:Ceftizoxime; D002511:Cephalosporins; D000097627:Cefpodoxime Proxetil