title: [Methodological characteristics of the preclinical study of the safety of drug preparations for children].
abstract: Some aspects of the preclinical study on safety of drugs used in children during experiments on immature animals are presented. Problems of the selection of animal species and the experimental schemes are discussed.
authors.forename: L F
authors.initials: LF
authors.lastname: Mal'tseva
authors.forename: G P
authors.initials: GP
authors.lastname: Muratova
authors.forename: V G
authors.initials: VG
authors.lastname: Motovilova
authors.forename: N A
authors.initials: NA
authors.lastname: Sirinova
mesh_terms: D000375:Aging / Q000187:drug effects; D000818:Animals; D000830:Animals, Laboratory; D002648:Child; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D004364:Pharmaceutical Preparations / Q000008:administration & dosage; D013997:Time Factors
chemical_list: D004364:Pharmaceutical Preparations
vernacular_title: Metodicheskie osobennosti doklinicheskogo izucheniia bezopasnosti lekarstvennykh preparatov dlia deteĭ.