TMCHB: a possible alternative to DNCB in skin testing for immune competence.
The desirability is considered of an alternative to dinitrochlorobenzene (DNCB) in assessing immune competence by skin testing. The choice of an alternative allergen is discussed, taking into account the different concentration which would be necessary for weaker allergens. The alternative proposed is 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-butenone (TMCHB).
Takanami
I
I
Department of Surgery, National Ohkura Hospital, Japan.
Nakayama
H
H
D000937:Antigen-Antibody Reactions; D002074:Butanones; D004137:Dinitrochlorobenzene; D006801:Humans; D009369:Neoplasms / Q000276:immunology*; D010328:Patch Tests / Q000379:methods*; D012882:Skin Tests / Q000379:methods*
D002074:Butanones; D004137:Dinitrochlorobenzene; C057540:1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-2-butenone