C-myc gene expression in heat-adapted and heat-shocked cells.
The steady-state level of c-myc transcripts increases in cells exposed to high temperatures. Therefore c-myc can be included with c-fos in the family of heat-inducible oncogenes. Activation of c-myc upon heat exposure could in turn account for the induction of heat-shock proteins but recent observations suggest also alternative interpretations.
Cajone
F
F
Istituto di Patologia Generale, Università degli Studi di Milano, Italy.
Salina
M
M
Bernelli-Zazzera
A
A
D000818:Animals; D005786:Gene Expression Regulation; D006360:Heat-Shock Proteins / Q000096:biosynthesis* / Q000235:genetics; D006358:Hot Temperature; D008546:Melanoma, Experimental / Q000235:genetics*; D051379:Mice; D009857:Oncogenes; D012333:RNA, Messenger / Q000032:analysis; D014407:Tumor Cells, Cultured / Q000502:physiology
D006360:Heat-Shock Proteins; D012333:RNA, Messenger