title: [Failure of chemonucleolysis and its surgical treatment. Apropos of 268 cases].
abstract: The authors have reviewed 268 cases of herniated lumbar discs treated by chemonucleolysis between 1980 and 1984. 52 patients had a laminectomy (19,40 p. 100) and 18 of theses failures were due to a large disc herniation (34,61 p. 100). The result of the surgical treatment after chemonucleolysis failure was good in 67,30 p. 100 of cases. A chymopapain injection is not indicated in patients with a large disc herniation.
authors.affiliation: Service de Rhumatologie A. Hôpital Cochin, Paris.
authors.forename: J S
authors.initials: JS
authors.lastname: Giraudet
authors.forename: H
authors.initials: H
authors.lastname: Carter
authors.forename: C J
authors.initials: CJ
authors.lastname: Menkes
authors.forename: A
authors.initials: A
authors.lastname: Chevrot
authors.forename: B
authors.initials: B
authors.lastname: Amor
authors.forename: J F
authors.initials: JF
authors.lastname: Hirsch
mesh_terms: D002917:Chymopapain / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D007404:Intervertebral Disc Chemolysis / Q000009:adverse effects; D007405:Intervertebral Disc Displacement / Q000188:drug therapy* / Q000601:surgery; D011843:Radiculopathy / Q000628:therapy*; D012189:Retrospective Studies
chemical_list: D002917:Chymopapain
vernacular_title: Les échecs de la chimionucléolyse et leur traitement chirurgical. A propos de 268 observations.