Pulmonary veno-occlusive disease associated with severe reduction of single-breath carbon monoxide diffusing capacity.
A 49-year-old woman presented with pulmonary hypertension, profound arterial hypoxemia, and a single-breath carbon monoxide diffusing capacity (DLCO) which was 17% of predicted. History, physical examination, and chest roentgenograms did not suggest the presence of parenchymal pulmonary disease. Spirometry and lung volume measurements were within normal limits. Pulmonary veno-occlusive disease was diagnosed by lung biopsy. This case illustrates the severe reduction of DLCO which can be associated with pulmonary veno-occlusive disease.
Elliott
C G
CG
University of Utah, Salt Lake City.
Colby
T V
TV
Hill
T
T
Crapo
R O
RO
D002248:Carbon Monoxide / Q000032:analysis*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications*; D008168:Lung / Q000473:pathology; D008875:Middle Aged; D011653:Pulmonary Diffusing Capacity; D011668:Pulmonary Veno-Occlusive Disease / Q000473:pathology / Q000503:physiopathology*
D002248:Carbon Monoxide