title: Trisomy 5 as sole anomaly in acute lymphoblastic leukemia.
abstract: We present a case of B-cell acute lymphoblastic leukemia (ALL) in whose leukemic cells trisomy 5 (+5) was the only cytogenetic anomaly observed. This is the first report of +5 as the sole cytogenetic abnormality in ALL; two cases (one questionable) of acute nonlymphocytic leukemia with such a change have been reported. The findings are presented in relation to other cases with +5 as part of a more complicated cytogenetic picture in hematologic disorders.
authors.affiliation: Cancer Center of Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
authors.forename: A A
authors.initials: AA
authors.lastname: Sandberg
authors.forename: S S
authors.initials: SS
authors.lastname: Morgan
authors.forename: R
authors.initials: R
authors.lastname: Morgan
authors.forename: L
authors.initials: L
authors.lastname: Boros
mesh_terms: D000328:Adult; D002051:Burkitt Lymphoma / Q000235:genetics*; D002895:Chromosomes, Human, Pair 5; D006801:Humans; D007621:Karyotyping; D008297:Male; D014314:Trisomy