In vitro activities of the newer beta-lactam and quinolone antimicrobial agents against Pseudomonas pseudomallei.
Imipenem was highly active and bactericidal against all 100 strains of Pseudomonas pseudomallei tested, followed in activity by piperacillin, carumonam, ceftazidime, cefotaxime, and ceftriaxone. The addition of clavulanic acid significantly increased the activities of both amoxicillin and ticarcillin. Ciprofloxacin and norfloxacin showed poor activity against test strains.
Ashdown
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LR
Pathology Laboratory, Commonwealth Department of Community Services and Health, Townsville, Queensland, Australia.
D042462:4-Quinolones; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects*; D047090:beta-Lactams
D042462:4-Quinolones; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D047090:beta-Lactams