title: [Acetoin metabolism in animal tissues].
abstract: The acetoin-synthesizing activity has been studied in the skeletal muscles, brain, liver and spleen homogenates (numbered as the activity decreases). The acetoin-synthesizing activity drastically increases in case of the acetaldehyde excess and alcohol intoxication. The acetaldehyde concentrations of above 1.10(-3) M inhibit the liver pyruvate dehydrogenase activity and increase the non-oxidative transformation of pyruvate. Acetoin is rapidly metabolized in the organism eliminating from blood 10 minutes after its injection. Acetoin is an effective precursor in the biosynthesis of lipids.
authors.forename: I B
authors.initials: IB
authors.lastname: Zavodnik
authors.forename: V U
authors.initials: VU
authors.lastname: Buko
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Ostrovskiĭ
mesh_terms: D000079:Acetaldehyde / Q000378:metabolism; D000093:Acetoin / Q000097:blood / Q000378:metabolism*; D000435:Alcoholic Intoxication / Q000097:blood / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D002074:Butanones / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D013154:Spleen / Q000378:metabolism
chemical_list: D002074:Butanones; D000093:Acetoin; D000079:Acetaldehyde
vernacular_title: Metabolizm atsetoina v zhivotnykh tkaniakh.