title: Squamous carcinoma of the gums.
abstract: We reviewed a 20-year experience with squamous carcinoma of the gums in 347 patients who received definitive therapy. More than three-quarters of the lesions involved the lower gum and all but 37 patients were previously untreated. The proportion of patients with localized tumors (N0) remained the same (64 percent). Surgery continued to be the treatment of choice in 97 percent of patients, but proportionately more patients had a more conservative procedure which preserved lower jaw continuity. The 5-year determinate survival rate was little changed (54 percent). Advanced clinical stage (stages III and IV), prior dental extraction, bone invasion, and involvement of surgical margins were predictive of a lower survival rate on univariate analysis. Clinical stage was the only significant predictor of survival on multivariate analysis. The impact of adjunctive radiotherapy could not be assessed.
authors.affiliation: Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
authors.forename: K C
authors.initials: KC
authors.lastname: Soo
authors.forename: R H
authors.initials: RH
authors.lastname: Spiro
authors.forename: W
authors.initials: W
authors.lastname: King
authors.forename: W
authors.initials: W
authors.lastname: Harvey
authors.forename: E W
authors.initials: EW
authors.lastname: Strong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005887:Gingival Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology; D008875:Middle Aged; D037981:Neck Dissection; D009361:Neoplasm Invasiveness; D011379:Prognosis