title: Transthoracic resection of esophageal cancer in patients with pulmonary dysfunction. Usefulness of high frequency ventilation during thoracotomy.
abstract: Although curative resection of esophageal cancer has become a safe procedure, in patients with pulmonary dysfunction, postoperative complications remain a serious problem. Of 122 patients who had transthoracic resection of esophageal cancer, 27 had pulmonary dysfunction; in six, the forced vital capacity was less than 70% (minimum of 42.8%, mean +/- SD of 56.6 +/- 8.9%); in 18, forced expiratory volume for one second (FEV1%) was less than 70% (minimum of 34.6%, mean +/- SD of 60 +/- 10%); and in three, both forced vital capacity and forced expiratory volume was less than 70%. Two patients had undergone hemipneumonectomy before receiving resection of the esophagus. During the intrathoracic operative procedure, high frequency ventilation was used, providing good surgical exposure and contributing to a decrease of postoperative pulmonary complications. There were no deaths during the month after surgery. The survival curve of these patients was not significantly different from that of other patients who had had esophagectomy for cancer of the esophagus. These patients survived for an average of 24 months. The patient who survived the longest has been alive for more than 11 years.
authors.affiliation: First Department of Surgery, Faculty of Medicine, Kyoto University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Imamura
authors.forename: K
authors.initials: K
authors.lastname: Yanagibashi
authors.forename: T
authors.initials: T
authors.lastname: Tobe
authors.forename: Y
authors.initials: Y
authors.lastname: Shimada
authors.forename: M
authors.initials: M
authors.lastname: Naito
authors.forename: T
authors.initials: T
authors.lastname: Arai
authors.forename: Y
authors.initials: Y
authors.lastname: Hatano
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000150:complications / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D004946:Esophagostomy; D005069:Evaluation Studies as Topic; D005260:Female; D005541:Forced Expiratory Volume; D005774:Gastrostomy; D006611:High-Frequency Jet Ventilation; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D008722:Methods; D008875:Middle Aged; D011013:Pneumonectomy; D012086:Reoperation; D013528:Surgical Staplers; D013908:Thoracotomy; D013990:Tidal Volume; D014797:Vital Capacity