title: Outer membrane permeation of Bacteroides fragilis by cephalosporins.
abstract: Outer membrane permeation of Bacteroides fragilis by cephalosporins was examined by a previously described method. The permeation parameters of cephalosporins in B. fragilis were close to 10(-5) cm3/min per microgram of cell dry weight. These values were about an order of magnitude lower than those in Escherichia coli. In B. fragilis, the permeation was not directly proportional to the hydrophilicity of cephalosporins, and the ion selectivity was weak.
authors.affiliation: Research Laboratory, Toyama Chemical Co., Ltd., Japan.
authors.forename: A
authors.initials: A
authors.lastname: Yotsuji
authors.forename: J
authors.initials: J
authors.lastname: Mitsuyama
authors.forename: R
authors.initials: R
authors.lastname: Hori
authors.forename: T
authors.initials: T
authors.lastname: Yasuda
authors.forename: I
authors.initials: I
authors.lastname: Saikawa
authors.forename: M
authors.initials: M
authors.lastname: Inoue
authors.forename: S
authors.initials: S
authors.lastname: Mitsuhashi
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism; D001441:Bacteroides fragilis / Q000378:metabolism*; D002463:Cell Membrane Permeability; D002511:Cephalosporins / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D008564:Membrane Potentials
chemical_list: D001425:Bacterial Outer Membrane Proteins; D002511:Cephalosporins