Treatment for AIDS and other retrovirus-caused diseases.
The role of retroviruses as causal agents in animal and human neoplasms is reviewed. Based on previous studies done on retrovirus caused mouse mammary adenocarcinoma, it is suggested that a treatment regimen with 6-propylthiouracil, chloroquine phosphate and 5-fluorouracil (which resulted in 77% and 65% complete mouse tumor remission), may be effective in treating AIDS and other retrovirus-caused diseases.
Shoemaker
J P
JP
Department of Biological Sciences, Ashland Community College, University of Kentucky 41101.
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000818:Animals; D002738:Chloroquine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D051379:Mice; D011441:Propylthiouracil / Q000627:therapeutic use*
C023676:chloroquine diphosphate; D011441:Propylthiouracil; D002738:Chloroquine; D005472:Fluorouracil