[Disorders of liver function, thrombopenia and hemolysis in a special clinical form of hypertension in pregnancy (the so-called HELLP syndrome)].
The so called HELLP syndrome is a severe complication of pregnancy-induced hypertension, characterized by haemolysis (H), elevated liver enzymes (EL) and low platelet counts (LP). The data of 37 patients with a HELLP syndrome are presented. In addition to the clinical symptoms of pregnancy-induced hypertension, 21 patients suffered from abdominal pain and 5 patients from icterus. Thrombocytopenia, haemolysis and elevated liver enzymes were observed in every case. In 28 of the patients a Caesarean section was performed to prevent further deterioration of the disease. Three patients died post partum as a consequence of severe complications. In five pregnancies intrauterine deaths were observed. The results of this retrospective study confirm the great risk for both the mother and the foetus, if pregnancy-induced hypertension is complicated by a so called HELLP syndrome.
Niesert
S
S
Frauenklinik der Medizinischen Hochschule Hannover.
Dribusch
E
E
Bellmann
O
O
Kaulhausen
H
H
Bettmann
O
O
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000743:Anemia, Hemolytic / Q000628:therapy*; D001219:Aspartate Aminotransferases / Q000097:blood; D002585:Cesarean Section; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D010976:Platelet Count; D011225:Pre-Eclampsia / Q000628:therapy*; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011379:Prognosis; D013577:Syndrome; D013921:Thrombocytopenia / Q000628:therapy*
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Leberfunktionsstörung, Thrombopenie und Hämolyse bei einer besonderen Verlaufsform der Schwangerschaftshypertonie (sog. HELLP-Syndrom).