An unusual case of extramedullary blast crisis in chronic myelocytic leukaemia.
A 27-year-old man with chronic myelocytic leukaemia sustained two episodes of extramedullary blast transformation. The first episode was a lymphoblastic transformation in his cervical lymph nodes, which was treated and in remission for 15 months when a second blastic transformation occurred in the meninges. All the while, the bone marrow was free from blastic crisis.
Feng
C S
CS
Haematology Laboratory, Prince of Wales Hospital, Shatin, N.T., Hong Kong.
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D001752:Blast Crisis / Q000188:drug therapy / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy / Q000235:genetics / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008578:Meninges / Q000473:pathology; D009333:Neck; D010677:Philadelphia Chromosome
D000970:Antineoplastic Agents