title: Intracavitary irradiation of carcinomas of the uterus and cervix: the Créteil method.
abstract: The Créteil method is a logical and simple system for intracavitary therapy of cervical and uterine cancer. The system is based on the use of a plastic cervico-vaginal moulage loaded with 0.5 mm diameter iridium 192 wire sources. The dimensions of both the moulage and the sources correspond to the size of the cervix being treated according to precisely defined relationships. The dose is specified on a reference isodose of a "fixed" value enclosing the pear-shaped target volume whose dimensions depend on the geometry of the sources. Source geometry in turn, depends on the size of the cervix. Thus, the dimensions of the target volume can be accurately predicted at the time of the application. Furthermore, treatment can be performed in a single application, with all sources having the same linear reference air kerma rate (or activity). Radioprotective measures are simple but effective and the patient is not subjected to the restrictions imposed by attachment to an after-loading apparatus. Our clinical results for early Stage T1 and T2a cervical tumors show excellent local control without major treatment complications or long term sequelae.
authors.affiliation: Département de Cancérologie C.H.U. Henri Mondor, Créteil, France.
authors.forename: B
authors.initials: B
authors.lastname: Pierquin
authors.forename: G
authors.initials: G
authors.lastname: Marinello
authors.forename: J P
authors.initials: JP
authors.lastname: Mege
authors.forename: J
authors.initials: J
authors.lastname: Crook
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*; D014594:Uterine Neoplasms / Q000532:radiotherapy*
chemical_list: D007496:Iridium Radioisotopes