title: Multiple chromosome aberrations in an infant with acute monoblastic leukemia.
abstract: A male infant was diagnosed at age 16 months with acute monoblastic leukemia. At diagnosis, studies of bone marrow revealed multiple chromosome aberrations: 48,XY,+8,+19,t(4;11). Chromosome studies have been repeated at remission and relapse over the course of his disease. To our knowledge, this combination of chromosome abnormalities has not been previously reported.
authors.affiliation: Department of Pediatrics, UMDNJ-School of Osteopathic Medicine, Camden 08103.
authors.forename: L E
authors.initials: LE
authors.lastname: McMorrow
authors.forename: B H
authors.initials: BH
authors.lastname: Greenbaum
authors.forename: S F
authors.initials: SF
authors.lastname: Travis
authors.forename: M H
authors.initials: MH
authors.lastname: Donaldson
authors.forename: M K
authors.initials: MK
authors.lastname: McCormack
mesh_terms: D001853:Bone Marrow / Q000648:ultrastructure; D002869:Chromosome Aberrations; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000235:genetics*; D008297:Male