[Functional reinnervation of a skeletal muscle by means of a peripheral nerve autograft to the spinal cord by dorsal approach. Study in the adult rat].
Peripheral nerve grafts were used in adult rats to join the spinal cord to a denervated skeletal muscle. From 2 to 5 months later, results of electrophysiological, histological and retrograde horseradish peroxidase labelling studies showed that spinal neurons, and especially motoneurons, were probably involved in the formation of new functional cholinergic neuromuscular junctions through these bridges.
Horvat
J C
JC
Laboratoire de Biologie-Vertébrés, Université Paris XI, Orsay, France.
Pecot-Dechavassine
M
M
Mira
J C
JC
D000818:Animals; D004594:Electrophysiology; D009046:Motor Neurons / Q000502:physiology; D009121:Muscle Denervation; D009132:Muscles / Q000294:innervation*; D009469:Neuromuscular Junction / Q000502:physiology; D009474:Neurons / Q000502:physiology; D010525:Peripheral Nerves / Q000637:transplantation*; D051381:Rats; D013116:Spinal Cord / Q000166:cytology / Q000502:physiology
Réinnervation fonctionnelle d'un muscle squelettique au moyen d'un autogreffon de nerf périphérique introduit dans la moelle épinière par voie dorsale. Etude chez le rat adulte.