title: [Treatment of severe postmenopausal osteoporosis].
abstract: The paper is concerned with the results of therapy of a severe form of postmenopausal osteoporosis in 5 patients using the combination of estrogens, 1-alpha-hydroxycholecalciferol and calcitonin. The treatment with the above drugs was accompanied by marked improvement of the general status. It was characterized by an increase in daily calcium excretion with urine, normalization of the concentration of calcium, inorganic phosphorus and serum alkaline phosphatase activity. A conclusion was made that the combined use of estrogens and 1-alpha-hydroxycholecalciferol produced a more marked clinical effect than each drug separately.
authors.forename: N A
authors.initials: NA
authors.lastname: Reĭsner
authors.forename: D A
authors.initials: DA
authors.lastname: Babarykin
authors.forename: I G
authors.initials: IG
authors.lastname: Vorona
authors.forename: A N
authors.initials: AN
authors.lastname: Riabukha
authors.forename: R L
authors.initials: RL
authors.lastname: Rozental'
mesh_terms: D000208:Acute Disease; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002116:Calcitonin / Q000627:therapeutic use; D002118:Calcium / Q000378:metabolism; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004997:Ethinyl Estradiol / Q000627:therapeutic use; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use; D008875:Middle Aged; D009644:Norgestrel / Q000627:therapeutic use; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism; D011859:Radiography
chemical_list: D006887:Hydroxycholecalciferols; D010758:Phosphorus; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination; D002116:Calcitonin; D002118:Calcium; C008088:alfacalcidol
vernacular_title: Lechenie tiazhelogo postmenopauzal'nogo osteoporoza.