title: Intense bone imaging agent uptake in the soft tissues of the lower legs and feet relating to ischemia and cold exposure.
abstract: We present a patient with diffuse and intense uptake in the soft tissues of both lower legs and feet seen on 99mTc-HMDP bone scintigraphy. This finding presumably resulted from compromised blood supply to the lower legs plus a cold environment. The extraosseous bone imaging agent localization was presumably related to an existing ischemic condition that was exacerbated by cold. Differential diagnosis of the scan pattern should be differentiated from the artifact of socks contaminated by radioactive urine.
authors.affiliation: Nuclear Medicine Service, VA Medical Center, Lexington, KY.
authors.forename: W J
authors.initials: WJ
authors.lastname: Shih
authors.forename: C
authors.initials: C
authors.lastname: Riley
authors.forename: S
authors.initials: S
authors.lastname: Magoun
authors.forename: U Y
authors.initials: UY
authors.lastname: Ryo
mesh_terms: D000368:Aged; D005627:Frostbite / Q000000981:diagnostic imaging*; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging*; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging*; D008297:Male; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives*
chemical_list: C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate