[Continuous superselective intra-arterial infusion with BUdR and 5 FU in combination with radiotherapy in the treatment of head and neck tumors].
Since 1984, a new method for intra-arterial administration of anti-cancer drug and radiosensitizer, named 'superselective continuous intra-arterial infusion therapy' has been used in combination with simultaneous irradiation, for the treatment of 67 patients with the head and neck tumors. Under fluoroscopy, a preshaped catheter was introduced retrogradely from the superficial temporal artery and inserted superselectively into the main feeding artery of the tumor. Through this catheter, continuous intra-arterial infusion chemotherapy was done. The primary therapeutic effects were appreciated as complete or partial response in all cases. It was considered that this method was more effective and with less adverse reactions for the treatment of the head and neck tumors compared with the conventional method.
Hattori
T
T
Dept. of Radiology, Mie Univ. School of Med.
Tashiro
T
T
Toyota
S
S
Hirano
T
T
Nakagawa
T
T
Yamaguchi
N
N
Sakakura
Y
Y
Murata
M
M
D001973:Bromodeoxyuridine / Q000008:administration & dosage* / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage* / Q000627:therapeutic use; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D007261:Infusions, Intra-Arterial; D008875:Middle Aged; D011879:Radiotherapy Dosage
D001973:Bromodeoxyuridine; D005472:Fluorouracil