title: Circadian changes in the secretory activity of nasal mucosa.
abstract: In this experiment the authors examined the nasal secretum of 36 normal subjects. Samples were taken at 10 a.m., 1 p.m., 4 p.m., 7 p.m., 10 p.m., 1 a.m., 4 a.m., for 3 days and 2 weeks later. SIgA, albumin and urea were measured in the secretum. The values obtained showed an increase in the three substances, when correlated to a different transudation during the 24 h, but the greater increase in SIgA must be attributed to an accentuated local production. Undoubtedly there exists a circadian modification in the production of SIgA, with higher values during the night than during the day.
authors.affiliation: ENT Department, University of L'Aquila, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Passàli
authors.forename: L
authors.initials: L
authors.lastname: Bellussi
mesh_terms: D000418:Albumins / Q000378:metabolism; D002940:Circadian Rhythm; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000378:metabolism*; D009297:Nasal Mucosa / Q000378:metabolism*; D014508:Urea / Q000378:metabolism
chemical_list: D000418:Albumins; D007071:Immunoglobulin A, Secretory; D014508:Urea