title: [Compounds similar to acyclovir. II. Synthesis of acyclic analogs of 2'-deoxynucleosides].
abstract: Acyclic analogues of nucleosides, viz.9- and 3-(1,6-dihydroxy-4-oxahex-3-yl)adenine, 9-(1,6-dihydroxy-4-oxahex-3-yl)guanine, 1-(1,6-dihydroxy-4-oxahex-3-yl)cytosine and thymine, with C3'-C4' bond of the furanose ring cleaved, have been prepared by condensation of trimethylsilyl derivatives of nucleic acid bases with 1,4,6-triacetoxy-3-oxahexane in the presence of Lewis acids followed by treatment with metanolic ammonia.
authors.forename: I L
authors.initials: IL
authors.lastname: Shchaveleva
authors.forename: I P
authors.initials: IP
authors.lastname: Smirnov
authors.forename: S V
authors.initials: SV
authors.lastname: Kochetkova
authors.forename: T L
authors.initials: TL
authors.lastname: Tsilevich
authors.forename: A A
authors.initials: AA
authors.lastname: Khorlin
mesh_terms: D000212:Acyclovir / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D003853:Deoxyribonucleosides / Q000138:chemical synthesis*
chemical_list: D003853:Deoxyribonucleosides; D000212:Acyclovir
vernacular_title: Soedineniia, podobnye atsikloviru. II. Sintez atsiklicheskikh analogov 2'-deoksinukleozidov.