Association of splenoma, peliosis and lipid histiocytosis in spleen or accessory spleen removed in 2 patients with chronic idiopathic thrombocytopenic purpura after long term treatment with steroids.
In 2 patients with a long lasting cortico-dependent chronic idiopathic thrombocytopenic purpura, splenectomy in one and ablation of an accessory spleen in the other, disclosed a complex association of splenoma, peliosis and lipidosis of the spleen, with a secondary sea blue histiocytosis in one case. The relation of this curious association with thrombocytopenia and with the long treatment with corticosteroids is discussed, with a review of the literature.
Diebold
J
J
Service Central Jacques Delarue d'Anatomie et de Cytologie Pathologiques, Hotel Dieu, Paris, France.
Audouin
J
J
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008206:Lymphatic Diseases / Q000473:pathology*; D008875:Middle Aged; D011696:Purpura, Thrombocytopenic / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000473:pathology*
D000305:Adrenal Cortex Hormones