title: Plasmacytic neoplasm of the gastrointestinal tract in a patient with long-standing monoclonal gammopathy.
abstract: We have reported the 21-year follow-up of a patient with progressive monoclonal IgG lambda gammopathy and recurrent pneumococcal infections who had diarrhea and weight loss. The serum IgG had risen from 2,850 mg/dl in 1966 to 6,120 mg/dl in 1986, but repeated evaluations had shown no evidence of myeloma or lymphoma. Evaluation revealed infiltration of the gastrointestinal tract by a plasmacytic malignancy with a surface heavy and light chain identical to her serum monoclonal band.
authors.affiliation: Department of Medicine (Division of Hematology), Vanderbilt University, Nashville, Tenn. 37232.
authors.forename: R T
authors.initials: RT
authors.lastname: Means
authors.forename: T L
authors.initials: TL
authors.lastname: McCurley
authors.forename: J M
authors.initials: JM
authors.lastname: Flexner
authors.forename: R S
authors.initials: RS
authors.lastname: Stein
mesh_terms: D001856:Bone Marrow Examination; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology*; D007074:Immunoglobulin G; D007414:Intestinal Neoplasms / Q000150:complications* / Q000188:drug therapy; D007421:Intestine, Small; D008875:Middle Aged; D010954:Plasmacytoma / Q000150:complications* / Q000188:drug therapy; D013997:Time Factors
chemical_list: D007074:Immunoglobulin G