Chronic renal failure and bladder augmentation: stomach versus sigmoid colon in the canine model.
A canine model for chronic renal failure and bladder augmentation with a segment of stomach or sigmoid colon (or control) was developed to evaluate the possible benefit of net chloride ion excretion noted in an earlier canine model for gastrocystoplasty. Gastrocystoplasty animals behaved similar to control animals relative to the sigmoid cystoplasty animals, tolerated significantly greater acid loading, did not have hyperchloremia with acidosis and had less weight loss with acidosis. Gastrocystoplasty seems to be superior to sigmoid cystoplasty in the azotemic canine.
Kennedy
H A
HA
James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis.
Adams
M C
MC
Mitchell
M E
ME
Rink
R C
RC
Piser
J A
JA
McNulty
A
A
D000138:Acidosis / Q000097:blood; D000643:Ammonium Chloride / Q000494:pharmacology; D000818:Animals; D001639:Bicarbonates / Q000097:blood; D003106:Colon / Q000637:transplantation*; D004285:Dogs; D005260:Female; D007676:Kidney Failure, Chronic / Q000473:pathology / Q000628:therapy*; D012965:Sodium Chloride / Q000097:blood; D013270:Stomach / Q000637:transplantation*; D001743:Urinary Bladder / Q000601:surgery*; D015431:Weight Loss
D001639:Bicarbonates; D000643:Ammonium Chloride; D012965:Sodium Chloride