Sibanomicin, a new pyrrolo[1,4]benzodiazepine antitumor antibiotic produced by a Micromonospora sp.
Itoh
J
J
Pharmaceutical Research Laboratories, Meiji Seika Kaisha, Ltd., Yokohama, Japan.
Watabe
H
H
Ishii
S
S
Gomi
S
S
Nagasawa
M
M
Yamamoto
H
H
Shomura
T
T
Sezaki
M
M
Kondo
S
S
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification* / Q000627:therapeutic use; D001569:Benzodiazepines / Q000302:isolation & purification / Q000627:therapeutic use; D055598:Chemical Phenomena; D002621:Chemistry; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007941:Leukemia P388 / Q000188:drug therapy; D008297:Male; D051379:Mice; D008826:Microbial Sensitivity Tests; D008847:Micromonospora / Q000032:analysis; D011758:Pyrroles / Q000302:isolation & purification / Q000627:therapeutic use
D000903:Antibiotics, Antineoplastic; D011758:Pyrroles; C057573:sibanomicin; D001569:Benzodiazepines