Methylcellulose for endothelial cell protection.
A randomised trial of three types of endothelial cell protection for patients undergoing posterior chamber intraocular lens implant is described. The results confirm the superiority of a viscoelastic fluid over air as a form of endothelial cell protection. No statistically significant difference was found between sodium hyaluronate and hydroxypropylmethylcellulose (HPMC). As the cost of sodium hyaluronate is prohibitive, a manufacturing technique for HPMC is given.
Steele
A D
AD
Moorfields Eye Hospital, London, UK.
Andrews
V
V
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000388:Air; D002387:Cataract Extraction / Q000009:adverse effects*; D004728:Endothelium, Corneal / Q000293:injuries*; D006801:Humans; D006820:Hyaluronic Acid; D065347:Hypromellose Derivatives; D007431:Intraoperative Complications / Q000517:prevention & control*; D007910:Lenses, Intraocular; D008747:Methylcellulose / Q000031:analogs & derivatives*; D008875:Middle Aged; D011897:Random Allocation
D065347:Hypromellose Derivatives; D006820:Hyaluronic Acid; D008747:Methylcellulose