Allergic bronchopulmonary aspergillosis progressing to allergic granulomatosis and angiitis (Churg-Strauss syndrome).
A 50-yr-old woman had a right upper lobectomy that revealed the pathologic changes of eosinophilic pneumonia and mucoid impaction. In the mucus plug within the segmental bronchus, aspergillus was demonstrated by direct staining. A diagnosis of allergic bronchopulmonary aspergillosis was made. After a latent period of 17 yr, she presented with the clinicopathologic features of the Churg-Strauss Syndrome. The putative role of aspergillus in the etiology of this syndrome is discussed.
Stephens
M
M
Department of Pathology, Llandough Hospital, Penarth, United Kingdom.
Reynolds
S
S
Gibbs
A R
AR
Davies
B
B
D000368:Aged; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000150:complications* / Q000473:pathology; D015267:Churg-Strauss Syndrome / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D009132:Muscles / Q000473:pathology