[Effect of a complex mixture of plasma proteins with heparin on the anticoagulation and fibrinolytic activity of the blood plasma in animals following intravenous administration of tissue thromboplastin].
The i.v. administration of 1.5 ml of the heparin complexes with plasma proteins prior to the injection of tissue thromboplastin induced a stronger neutralization of formed thrombin in the blood and higher anticoagulating and fibrinolytic activities in albino rats as compared to the injection of tissue thromboplastin alone.
Pastorova
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D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001798:Blood Proteins / Q000494:pharmacology*; D004338:Drug Combinations; D005340:Fibrinogen / Q000032:analysis; D005342:Fibrinolysis / Q000187:drug effects*; D006493:Heparin / Q000494:pharmacology*; D007275:Injections, Intravenous; D008297:Male; D051381:Rats; D013917:Thrombin / Q000032:analysis; D013918:Thrombin Time; D013925:Thromboplastin / Q000494:pharmacology*; D013997:Time Factors
D001798:Blood Proteins; D004338:Drug Combinations; D005340:Fibrinogen; D006493:Heparin; D013925:Thromboplastin; D013917:Thrombin
Vliianie kompleksnoĭ smesi belkov plazmy s geparinom na antikoaguliantnuiu i fibrinoliticheskuiu aktivnost' plazmy krovi zhivotnykh pri vnutrivennom vvedenii tkanevogo tromboplastina.