[Effect of dalargin on the behavior of rats subjected to intrauterine ethanol exposure].
Influence was studied of dalargin--synthetic analogue of enkephalin administered in early postnatal period to young rats with intrauterine ethanol injection, on their behaviour and conditioned activity. Parameters were established of spontaneous motor activity, behaviour in the open field, acquisition and preservation of conditioned reflexes of passive and active avoidance in experimental and intact rats, injected with dalargin. A reduction of sensitivity to corasol convulsive effect was observed under the influence of dalargin.
Maĭzelis
M Ia
MIa
Zabludovskiĭ
A L
AL
Shikhov
S N
SN
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D001522:Behavior, Animal / Q000187:drug effects*; D003214:Conditioning, Classical / Q000187:drug effects; D004347:Drug Interactions; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives* / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D010433:Pentylenetetrazole / Q000494:pharmacology; D010812:Physical Stimulation; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats
D000431:Ethanol; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-; D010433:Pentylenetetrazole
Vliianie dalargina na povedenie krys, podvergavshikhsia vnutriutrobnym vozdeĭstviiam étanola.