[Long-term remission induced by measles infection and followed by immunosuppressive therapy in a case of refractory juvenile rheumatoid arthritis].
A case of severe juvenile rheumatoid arthritis, polyarticular type, refractory to FANS and long acting therapy which showed a quick remission after measles is described. An immunosuppressive therapy to strengthen the immunosuppression induced by virus infection was performed for six months. The remission has been maintained for 4 years and appears up to now to be stable with no therapy. On the basis of this observation, the possibility of a vaccination therapy with measles virus, which equally gives immunosuppression, is discussed.
Lepore
L
L
Clinica Pediatrica, Istituto per l'Infanzia Burlo Garofolo, Trieste, Italia.
Agosti
E
E
Pennesi
M
M
Barbi
E
E
De Manzini
A
A
D001171:Arthritis, Juvenile / Q000188:drug therapy / Q000276:immunology*; D001241:Aspirin / Q000627:therapeutic use; D001379:Azathioprine / Q000008:administration & dosage / Q000627:therapeutic use*; D002675:Child, Preschool; D004008:Diclofenac / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008457:Measles / Q000276:immunology*; D012074:Remission Induction; D013997:Time Factors
D004008:Diclofenac; D001379:Azathioprine; D001241:Aspirin; D007213:Indomethacin
Remissione a lungo termine in caso di artrite reumatoide giovanile intrattabile indotta da infezione morbillosa seguita da terapia immunosoppressiva.