Multiple chromosome aberrations in an infant with acute monoblastic leukemia.
A male infant was diagnosed at age 16 months with acute monoblastic leukemia. At diagnosis, studies of bone marrow revealed multiple chromosome aberrations: 48,XY,+8,+19,t(4;11). Chromosome studies have been repeated at remission and relapse over the course of his disease. To our knowledge, this combination of chromosome abnormalities has not been previously reported.
McMorrow
L E
LE
Department of Pediatrics, UMDNJ-School of Osteopathic Medicine, Camden 08103.
Greenbaum
B H
BH
Travis
S F
SF
Donaldson
M H
MH
McCormack
M K
MK
D001853:Bone Marrow / Q000648:ultrastructure; D002869:Chromosome Aberrations; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000235:genetics*; D008297:Male