Pharmacokinetics of fluoride absorbed from dried seafoods by healthy adults.
Dried seafoods are a rich source of fluoride (F). The systemic availability of F from seafoods was studied in 3 healthy adults. The plasma concentration and urinary excretion of F for 24 h following the ingestion of 3.87 +/- 0.32 mg F (mean +/- SD) in seafoods were compared with plasma and urine data following oral administration of 3 mg F in aqueous solution. There was a marked reduction and delay in the absorption of F from seafoods. The relative bioavailability of F from seafoods was 40.8 +/- 5.1%. These findings should be taken into consideration when determining the optimum level of daily F intake.
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Department of Cariology, Faculty of Dentistry, Jordan University of Science and Technology, Irbid.
D000328:Adult; D000818:Animals; D001682:Biological Availability; D005260:Female; D005399:Fishes; D005459:Fluorides / Q000097:blood / Q000493:pharmacokinetics* / Q000652:urine; D006801:Humans; D008297:Male; D008460:Meat / Q000032:analysis*; D012758:Shellfish / Q000032:analysis*
D005459:Fluorides