title: [Intraoperative sedation by midazolam during spinal anesthesia. A study of elderly women undergoing surgery of the hip and femur neck].
abstract: Midazolam was studied as an IV sedative agent in 30 women aged of 75 years or more, undergoing hip surgery or Ender nailing, who received a spinal anaesthesia with 15 mg of plain bupivacaine. A mean dose of midazolam 0.077 mg.kg-1 was required to induce adequate sedation which was maintained by repeated doses of 2.5 mg. Post-operatively, no somnolence was noted at 2 hr. A marked amnesic effect was observed in 77% of cases. No clinically adverse cardiovascular or respiratory effects were encountered. It is concluded that midazolam is a useful sedative agent for spinal anaesthesia of short duration in the elderly.
authors.affiliation: Service d'anesthésiologie, Centre hospitalier de Chalon-sur-Saône.
authors.forename: J P
authors.initials: JP
authors.lastname: Racle
authors.forename: E
authors.initials: E
authors.lastname: Cenon
authors.forename: L
authors.initials: L
authors.lastname: Jourden
authors.forename: A
authors.initials: A
authors.lastname: Benkhadra
authors.forename: J Y
authors.initials: JY
authors.lastname: Poy
authors.forename: F
authors.initials: F
authors.lastname: Fockenier
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000775:Anesthesia, Spinal; D005260:Female; D005265:Femoral Neck Fractures / Q000601:surgery*; D005594:Fracture Fixation, Intramedullary; D006622:Hip Prosthesis; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D007432:Intraoperative Period; D008874:Midazolam / Q000008:administration & dosage*
chemical_list: D006993:Hypnotics and Sedatives; D008874:Midazolam
vernacular_title: Sédation per-opératoire par le midazolam au cours des rachianesthésies. Etude chez la femme âgée en chirurgie de la hanche et du col du fémur.