[Bicarbonate hemodialysis in the therapy of chronic kidney failure].
A method of random sampling was applied to 10 CRI patients to analyze the results of 24 hemodialyses with acetate solution for dialysis (35 mmol/l) and 34 hemodialyses with bicarbonate solution for dialysis (35 mmol/l). Significant reduction of complications like headache, nausea, vomiting, tachycardia, dyspnea, extrasystole was observed in bicarbonate dialysis. The concentration of mean molecular uremic toxins was decreased from 5.75 +/- 0.84 mmol/l in acetate dialysis up to 2.63 +/- 0.21 mmol/l in bicarbonate dialysis. The content of intracellular potassium returned to normal. The concentration of serum cholesterol was decreased from 5.6 +/- 0.4 up to 4.8 +/- 0.2 mmol/l. These data indicated a favorable effect of bicarbonate dialysis on intracellular metabolism. Preliminary data did not confirm the normalizing effect of bicarbonate dialysis on the development of uremic osteopathy.
Riabov
S I
SI
Shostka
G D
GD
Spiridonov
V N
VN
Vasil'ev
A N
AN
Kozlov
V V
VV
D000085:Acetates / Q000009:adverse effects / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D001639:Bicarbonates / Q000009:adverse effects / Q000627:therapeutic use*; D015314:Dialysis Solutions / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D005260:Female; D015312:Hemodialysis Solutions / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods*
D000085:Acetates; D001639:Bicarbonates; D015314:Dialysis Solutions; D015312:Hemodialysis Solutions
Bikarbonatnyĭ gemodializ v terapii khronicheskoĭ pochechnoĭ nedostatochnosti.