Peripheral relaxin levels during pregnancy in a woman with homozygous familial hypobetalipoproteinemia.
A case of a normal pregnancy conceived spontaneously in a 22-year-old woman with hypobetalipoproteinemia evidenced peripheral levels of relaxin in the range of uncomplicated singleton pregnancies in conjunction with low peripheral levels of progesterone. The establishment and maintenance of uterine quiescence in this hypoprogestational pregnancy may be attributable to these "normal" relaxin concentrations or to local uterine factors, including decidual relaxin production, which would not be reflected in circulating relaxin levels.
Schmidt
C L
CL
Department of Obstetrics and Gynecology, UMDNJ, New Jersey Medical School, Newark 07103.
Goldsmith
L T
LT
Carr
B R
BR
Weiss
G
G
Parker
C R
CR
Illingworth
D R
DR
D000328:Adult; D005260:Female; D006801:Humans; D006995:Hypobetalipoproteinemias / Q000097:blood*; D007009:Hypolipoproteinemias / Q000097:blood*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D011374:Progesterone / Q000097:blood; D012065:Relaxin / Q000097:blood*
D011374:Progesterone; D012065:Relaxin