Effect of structure on biological tolerance. Comparison of triiodobenzene derivatives.
Synthesis of basic structures of contrast media is reviewed. Biological tolerance of ionic and nonionic derivatives of triiodobenzene are related to the degree of withdrawal of electrons from their aromatic systems.
Gries
H
H
Institute of Contrast Media Research, Schering AG, Berlin-Bergkamen, West Germany.
Mützel
W
W
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D003287:Contrast Media; D006801:Humans; D007463:Iodobenzoates; D013329:Structure-Activity Relationship; D014283:Triiodobenzoic Acids
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; C057936:2,4,6-triiodotrimesic acid