[The duration of cell cycle phases studied using 5-bromodeoxycytidine].
The quantitative method is suggested to estimate cell cycle phase durations and dispersions of progress through the phases for population of cells. The method is based on the analysis of frequency of cells with different staining of sister chromatids by means of 5-bromodeoxycytidine. The process of cell population progress is described by the Gauss probability integral. The durations of the cell cycle phases are determined for cell culture of Chinese hamster.
Golovina
M E
ME
Smirnova
T D
TD
Chebotarev
A N
AN
D000818:Animals; D001972:Bromodeoxycytidine / Q000494:pharmacology*; D002453:Cell Cycle / Q000187:drug effects*; D002478:Cells, Cultured; D002875:Chromosomes / Q000187:drug effects; D006224:Cricetinae; D003412:Cricetulus; D003841:Deoxycytidine / Q000031:analogs & derivatives*; D007399:Interphase / Q000187:drug effects; D008433:Mathematics; D013997:Time Factors
D003841:Deoxycytidine; D001972:Bromodeoxycytidine
Izuchenie prodolzhitel'nosti faz kletochnogo tsikla s pomoshch'iu 5-bromdezoksitsitidina.