Anaerobic metabolism of phthalate and other aromatic compounds by a denitrifying bacterium.
The anaerobic metabolism of phthalate and other aromatic compounds by the denitrifying bacterium Pseudomonas sp. strain P136 was studied. Benzoate, cyclohex-1-ene-carboxylate, 2-hydroxycyclohexanecarboxylate, and pimelate were detected as predominant metabolic intermediates during the metabolism of three isomers of phthalate, m-hydroxybenzoate, p-hydroxybenzoate, and cyclohex-3-ene-carboxylate. Inducible acyl-coenzyme A synthetase activities for phthalates, benzoate, cyclohex-1-ene-carboxylate, and cyclohex-3-ene-carboxylate were detected in the cells grown on aromatic compounds. Simultaneous adaptation to these aromatic compounds also occurred. A similar phenomenon was observed in the aerobic metabolism of aromatic compounds by this strain. A new pathway for the anaerobic metabolism of phthalate and a series of other aromatic compounds by this strain was proposed. Some properties of the regulation of this pathway were also discussed.
Nozawa
T
T
Department of Agricultural Chemistry, Faculty of Agriculture, University of Tokyo, Japan.
Maruyama
Y
Y
D000693:Anaerobiosis; D001565:Benzoates / Q000378:metabolism; D007700:Kinetics; D015394:Molecular Structure; D010795:Phthalic Acids / Q000378:metabolism*; D011549:Pseudomonas / Q000254:growth & development / Q000378:metabolism*; D013329:Structure-Activity Relationship
D001565:Benzoates; D010795:Phthalic Acids