title: Destructive skeletal lesions as the primary initial manifestation of acute childhood leukemia.
abstract: Bony involvement in leukemia has been long recognized in the medical literature. However, severe osseous changes, as the sole initial manifestation of childhood leukemia is a unique feature of the case reported here.
authors.affiliation: Southern Illinois University School of Medicine, Department of Pediatrics, Springfield 62708.
authors.forename: J
authors.initials: J
authors.lastname: Akber
authors.forename: M T
authors.initials: MT
authors.lastname: Gallagher
authors.forename: L
authors.initials: L
authors.lastname: Mathew
authors.forename: D
authors.initials: D
authors.lastname: Ayoub
authors.forename: T D
authors.initials: TD
authors.lastname: Miale
mesh_terms: D000911:Antibodies, Monoclonal; D001853:Bone Marrow / Q000276:immunology / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000276:immunology; D002648:Child; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal