title: Fungal keratitis in contact lens wearers.
abstract: In a retrospective review from 1972 through 1987 of patients with microbial keratitis, fungal infection occurred in four (4%) of 90 cosmetic or aphakic contact lens wearers and in four (27%) of 15 patients using a therapeutic soft contact lens. Predisposing factors included improper lens care by the refractive lens wearers and a chronic epithelial defect with topical corticosteroid use among the therapeutic lens wearers. The responsible organisms in the refractive lens group were Fusarium solani (two patients) and Cephalosporium and Paecilomyces (one patient each), and in the therapeutic lens group Candida (three patients) and Aspergillus (one patient). Filamentous fungi were more likely to be associated with cosmetic or aphakic lens wear, whereas yeasts were more frequently found with therapeutic lens use.
authors.affiliation: Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas.
authors.forename: K R
authors.initials: KR
authors.lastname: Wilhelmus
authors.forename: N M
authors.initials: NM
authors.lastname: Robinson
authors.forename: R A
authors.initials: RA
authors.lastname: Font
authors.forename: M B
authors.initials: MB
authors.lastname: Hamill
authors.forename: D B
authors.initials: DB
authors.lastname: Jones
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000382:microbiology / Q000601:surgery; D005260:Female; D006801:Humans; D007634:Keratitis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D012189:Retrospective Studies
chemical_list: D000935:Antifungal Agents