title: [Disorders of liver function, thrombopenia and hemolysis in a special clinical form of hypertension in pregnancy (the so-called HELLP syndrome)].
abstract: The so called HELLP syndrome is a severe complication of pregnancy-induced hypertension, characterized by haemolysis (H), elevated liver enzymes (EL) and low platelet counts (LP). The data of 37 patients with a HELLP syndrome are presented. In addition to the clinical symptoms of pregnancy-induced hypertension, 21 patients suffered from abdominal pain and 5 patients from icterus. Thrombocytopenia, haemolysis and elevated liver enzymes were observed in every case. In 28 of the patients a Caesarean section was performed to prevent further deterioration of the disease. Three patients died post partum as a consequence of severe complications. In five pregnancies intrauterine deaths were observed. The results of this retrospective study confirm the great risk for both the mother and the foetus, if pregnancy-induced hypertension is complicated by a so called HELLP syndrome.
authors.affiliation: Frauenklinik der Medizinischen Hochschule Hannover.
authors.forename: S
authors.initials: S
authors.lastname: Niesert
authors.forename: E
authors.initials: E
authors.lastname: Dribusch
authors.forename: O
authors.initials: O
authors.lastname: Bellmann
authors.forename: H
authors.initials: H
authors.lastname: Kaulhausen
authors.forename: O
authors.initials: O
authors.lastname: Bettmann
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000743:Anemia, Hemolytic / Q000628:therapy*; D001219:Aspartate Aminotransferases / Q000097:blood; D002585:Cesarean Section; D005260:Female; D006801:Humans; D008111:Liver Function Tests; D010976:Platelet Count; D011225:Pre-Eclampsia / Q000628:therapy*; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011379:Prognosis; D013577:Syndrome; D013921:Thrombocytopenia / Q000628:therapy*
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
vernacular_title: Leberfunktionsstörung, Thrombopenie und Hämolyse bei einer besonderen Verlaufsform der Schwangerschaftshypertonie (sog. HELLP-Syndrom).