Use of a predictor for total body potassium content: application to nutrition and hypertension.
Total body potassium (TBK), measured at different institutions, has no reference standard for comparison. A useful reference formula, however, based on body size and age, has been derived at the Brookhaven National Laboratory. This formula was used to help calibrate a simple whole body counter for measuring total potassium and applied to nutrition and hypertension studies. A sodium iodide detector was used for counting gamma rays emitted by potassium-40 to estimate TBK. The mean ratio (+/- S.D.) of adjusted TBK measurements to predicted values was 1.002 +/- 0.047. The ratio of lean body mass estimated by the TBK measurement to that derived from skin fold thickness was 1.069 +/- 0.056. In hypertensives on low dose thiazide, the ratio of TBK measurements to predicted values was 0.994 +/- 0.052. Thus, our TBK measurements were adjusted in close agreement with a predictor formula, provided higher estimates of lean body mass than did skin fold thickness, and showed no change in thiazide treated hypertensives.
Goldenberg
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Department of Medicine, Wright State University, Dayton, OH 45435.
Tomlinson
F K
FK
D000328:Adult; D000368:Aged; D001823:Body Composition; D001824:Body Constitution; D002138:Calibration; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D011188:Potassium / Q000032:analysis*; D011197:Potassium Radioisotopes; D012015:Reference Standards; D012885:Skinfold Thickness
D011197:Potassium Radioisotopes; D011188:Potassium