title: The extraction, isolation and identification of the purgative component of Croton penduliflorus seed oil.
abstract: The purgative principles in Croton penduliflorus seed oil were isolated as white crystals by a bioassay-guided chromatographic separation process. The crystals were recovered in 7% w/w yield and identified (IR, 1H-NMR, GC-MS) as a mixture of palmitic, stearic and arachidic acids in approximately equimolar concentration.
authors.affiliation: Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka.
authors.forename: I U
authors.initials: IU
authors.lastname: Asuzu
authors.forename: A I
authors.initials: AI
authors.lastname: Gray
authors.forename: P G
authors.initials: PG
authors.lastname: Waterman
mesh_terms: D000818:Animals; D001681:Biological Assay; D002400:Cathartics / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D003436:Croton Oil / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D005260:Female; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects; D008297:Male; D051379:Mice; D012639:Seeds
chemical_list: D002400:Cathartics; D003436:Croton Oil