The effect of biopreparation cACPL on the proliferative activity of haemopoietic and tumour cells.
The haemotoxicity and antitumour activity of crude anticancer phospholipid (cACPL) was evaluated. Results of our experiments gave evidence that the cACPL has no ill effects on haemopoietic stem cells but it markedly stimulates their proliferation. There was little if any anticancer activity of cACPL proved in experiments with murine lymphosarcoma LS/BL and carcinoma EAT cells.
Jurásková
V
V
Institute of Biophysics, Czechoslovak Academy of Sciences, Brno.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D002455:Cell Division / Q000187:drug effects; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy*; D051379:Mice; D008815:Mice, Inbred Strains; D010743:Phospholipids / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology; D014410:Tumor Stem Cell Assay
D000970:Antineoplastic Agents; D010743:Phospholipids