[The interrelation of the sodium-excretory function of the kidneys and vascular reactivity in hypertension patients].
Vascular reactivity was evaluated by a modified photoplethysmographic method in 20 patients with essential hypertension before and after an acute volumetric salt load. A relationship was demonstrated between vascular reactivity and renal sodium excretion pattern under stress. Patients with "excessive" natriuresis 24 h after the test showed reduced vascular reactivity, and slow sodium and water excretion was associated with increased vascular response. A study of membrane Ca2+ transport 24 h after the test showed an increase in receptor-dependent Ca2+ uptake in response to all inductors (platelet aggregation factor, vasopressin, ADP), as compared to the baseline.
Shkhvatsabaia
I K
IK
Zharova
E A
EA
Oshchepkova
E V
EV
Kravchenko
A N
AN
Pershakova
L P
LP
D000328:Adult; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D002118:Calcium / Q000097:blood; D004231:Diuresis / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology*; D008297:Male; D008833:Microcirculation / Q000187:drug effects / Q000503:physiopathology; D008875:Middle Aged; D009318:Natriuresis / Q000187:drug effects; D009638:Norepinephrine; D012867:Skin / Q000098:blood supply*; D012965:Sodium Chloride
D012965:Sodium Chloride; D002118:Calcium; D009638:Norepinephrine
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