[Effect on the systemic hemodynamics of polymers that decrease hydrodynamic resistance].
It has been shown that intravenous injections of drug-reducing polymers (at a dose of 2 x1 0(-6) g/ml) to rabbits produced a decrease in the total peripheral resistance with an increase in the cardiac output and simultaneous diminution of the mean blood pressure. These hemodynamic effects did not depend on vasodilatation as it had previously been shown. The alterations were retained for not less than 72 hours after one polymer injection; the effects were due to the influence of polymers on the flow structure.
Gannushkina
I V
IV
Kameneva
M V
MV
Antelava
A L
AL
D000818:Animals; D003864:Depression, Chemical; D006439:Hemodynamics / Q000187:drug effects*; D008970:Molecular Weight; D011092:Polyethylene Glycols / Q000494:pharmacology; D011108:Polymers / Q000494:pharmacology*; D011817:Rabbits; D013997:Time Factors; D014655:Vascular Resistance / Q000187:drug effects*
D011108:Polymers; D011092:Polyethylene Glycols
Vliianie na sistemnuiu gemodinamiku polimerov, snizhaiushchikh gidrodinamicheskoe soprotivlenie.