[Effect of 2-pyrrolidone and gamma-butyrolactone on the rate of 14C-leucine incorporation into the proteins of different brain structures and of their arterial tissues].
The ability of cyclic GABA and GHBA derivatives--2-pyrrolidone and gamma-butyrolactone--to increase markedly the inclusion of 14C-leucine in the proteins of hypothalamus and cerebral arteries both normally and in condition of cerebral blood supply disturbances produced by unilateral 20 min ligation of a common carotid artery has been demonstrated.
Mirzoian
S A
SA
Zalinian
M G
MG
Gevorkian
G A
GA
Topchian
A V
AV
Balasanian
M G
MG
D015107:4-Butyrolactone / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D002250:Carbon Radioisotopes; D002536:Cerebral Arteries / Q000187:drug effects* / Q000378:metabolism; D005663:Furans / Q000494:pharmacology*; D002534:Hypoxia, Brain / Q000378:metabolism; D007930:Leucine / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D011760:Pyrrolidinones / Q000494:pharmacology*; D051381:Rats
D002250:Carbon Radioisotopes; D005663:Furans; D009419:Nerve Tissue Proteins; D011760:Pyrrolidinones; D007930:Leucine; C028537:2-pyrrolidone; D015107:4-Butyrolactone
Vliianie pirrolidona-2 i gamma-butirolaktona na skorost' vkliucheniia 14C-leĭtsina v belki razlichnykh struktur golovnogo mozga i tkaneĭ ego arteriĭ.