title: [A combination of kordaron with ritmilen: its effect on the electrophysiology of the heart and its clinical effectiveness].
abstract: Combined effect of cordarone and ritmilen on myocardial electrophysiology was assessed in an acute medicated test, on the basis of electrophysiologic studies and transesophageal pacing test, in patients with resistant paroxysmal supraventricular tachycardia. The cordarone-ritmilen combination has proved efficient in 82.4% of cases and caused a significant change of the P-Q interval and effective refractory period (ERPav, ERPrv, ERPiv). The Q-T interval increased but never resulted in ventricular arrhythmias. Good antiarrhythmic effect was seen in 70.4% after 12 months. There were side effects in 10.7% of cases.
authors.forename: E O
authors.initials: EO
authors.lastname: Gimrikh
authors.forename: I V
authors.initials: IV
authors.lastname: Gushchin
authors.forename: A M
authors.initials: AM
authors.lastname: Chekhov
authors.forename: S V
authors.initials: SV
authors.lastname: Popov
authors.forename: A I
authors.initials: AI
authors.lastname: Mikhaĭlenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D002304:Cardiac Pacing, Artificial; D004206:Disopyramide / Q000627:therapeutic use; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D004594:Electrophysiology; D005260:Female; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D004206:Disopyramide; D000638:Amiodarone
vernacular_title: Kombinatsiia kordarona s ritmilinom: vliianie na élektrofiziologiiu serdtsa i klinicheskaia Teffektivnost'.