[Compounds similar to acyclovir. I. Synthesis of "complete" analogs of nucleosides].
"Full" acyclic analogues of ribonucleosides, 1-(1,2,6-trihydroxy-4-oxahex-3-yl)thymine and -cytosine, 3- and 9-(1,2,6-trihydroxy-4-oxahex-3-yl)adenine, and 9-(1,2,6-trihydroxy-4-oxahex-3-yl)guanine, have been prepared by condensation of silylated nucleo-bases with 1,4,5,6-tetraacetoxy-3-oxahexane in the presence of Lewis acids followed by deacetylation.
Kochetkova
S V
SV
Tsilevich
T L
TL
Smirnov
I P
IP
Shchaveleva
I L
IL
Khorlin
A A
AA
D000212:Acyclovir / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D009705:Nucleosides / Q000138:chemical synthesis*
D009705:Nucleosides; D000212:Acyclovir
Soedineniia, podobnye atikloviru. I. Sintez "polnykh" atiklicheskikh analogov nukleozidov.