title: Association of Guillain-Barré syndrome and Henoch-Schönlein purpura: is immunoglobulin a responsible for the neurologic syndrome?
abstract: Guillain-Barré syndrome and Henoch-Schönlein purpura (HSP) appeared simultaneously in a 35-year-old woman. During the course of the Guillain-Barré syndrome, the presence of IgA aggregates and a decrease in complement components were noted in the cerebrospinal fluid. These abnormalities disappeared when the neurologic syndrome remitted. This suggests the responsibility of IgA immune complexes, characteristic of HSP, in the occurrence of the associated Guillain-Barré syndrome.
authors.affiliation: Department of Pneumology, Pitié-Salpétrière Hospital, Paris, France.
authors.forename: B A
authors.initials: BA
authors.lastname: Moreau
authors.forename: E
authors.initials: E
authors.lastname: Schuller
authors.forename: B
authors.initials: B
authors.lastname: Georges
mesh_terms: D000328:Adult; D003176:Complement C3 / Q000032:analysis / Q000134:cerebrospinal fluid; D003181:Complement C4 / Q000032:analysis / Q000134:cerebrospinal fluid; D004576:Electromyography; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D007070:Immunoglobulin A / Q000032:analysis / Q000134:cerebrospinal fluid*; D011129:Polyradiculoneuropathy / Q000150:complications* / Q000276:immunology
chemical_list: D003176:Complement C3; D003181:Complement C4; D007070:Immunoglobulin A