Activities of compound G2 isolated from alfalfa roots against dermatophytes.
An antimycotic agent, compound G2, isolated from alfalfa roots exhibited considerable activity against the six most common dermatophytes. MICs in agar and broth dilutions ranged from 10 to 30 micrograms/ml and from 2 to 10 micrograms/ml, respectively. G2 was fungicidal at 5 to 22 micrograms/ml. Structure and toxicity relations are discussed.
Evron
R
R
Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel.
Polacheck
I
I
Guizie
M
M
Levy
M
M
Zehavi
U
U
D000935:Antifungal Agents / Q000494:pharmacology*; D004821:Epidermophyton / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects*; D014249:Trichophyton / Q000187:drug effects*; D014315:Triterpenes / Q000494:pharmacology*
D000935:Antifungal Agents; D014315:Triterpenes; C049077:medicagenic acid-3-O-glucopyranoside