title: [Regulation of lipid peroxidation induced by cumene hydroperoxide in the liver mitochondria of irradiated rats].
abstract: A study was made of the accumulation of lipoperoxidation products and O2- generation induced by cumene hydroperoxide in mitochondria of irradiated rat liver. O2- generation and formation of lipoperoxidation products were found to be connected with the function of mitochondrial P-450 cytochrome. During the first 24 h following X-irradiation of rats with a dose of 10 Gy, the rate of O2- generation sharply increased and mitochondria could not regulate the intensity of lipoperoxidation with incubation medium tonicity being altered.
authors.forename: T I
authors.initials: TI
authors.lastname: Gudz'
authors.forename: S A
authors.initials: SA
authors.lastname: Novgorodov
authors.forename: I G
authors.initials: IG
authors.lastname: Pandelova
authors.forename: G A
authors.initials: GA
authors.lastname: Kakabadze
authors.forename: L S
authors.initials: LS
authors.lastname: Iaguzhinskiĭ
mesh_terms: D000818:Animals; D001555:Benzene Derivatives / Q000494:pharmacology*; D007477:Ions; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D010100:Oxygen; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013268:Stimulation, Chemical
chemical_list: D001555:Benzene Derivatives; D007477:Ions; D008054:Lipid Peroxides; C007164:cumene hydroperoxide; D010100:Oxygen
vernacular_title: Reguliatsiia lipoperoksidatsii, indutsirovannoĭ gidroperekis'iu kumila, v mitokhondriiakh pecheni obluchennykh krys.