Irreversible inhibition by tyrosine-directed alkylating reagents of muscarinic cholinergic receptors in membranes from rat forebrain and heart.
Wang
J X
JX
Department of Pharmacology, University of Arizona, Tucson 85724.
Yamamura
H I
HI
Wang
W
W
Roeske
W R
WR
D000477:Alkylating Agents / Q000494:pharmacology*; D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D006321:Heart / Q000187:drug effects*; D066298:In Vitro Techniques; D008297:Male; D009206:Myocardium / Q000378:metabolism; D011813:Quinuclidinyl Benzilate / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D011976:Receptors, Muscarinic / Q000187:drug effects*; D014443:Tyrosine / Q000502:physiology*
D000477:Alkylating Agents; D011976:Receptors, Muscarinic; D014443:Tyrosine; D011813:Quinuclidinyl Benzilate