[The effect of some possible factors in c-peptide immunoreactivity in urine on the quality of the results].
About 15% of CPR-U did not correspond between two kinds of kits in the routine assay, which were produced by different pharmaceutical firms, and also it is realised that the effect of the preservative, storage condition and buffer dilutions can not be overlooked in quality control programmes. Based on these problems, following results are concluded; (1) Urine preservative: NaN3 is better than toluene. (2) Urine CPR was stable for added preservative at 4 degrees C for two weeks. (3) Diluents may effect the CPR-U results, if not kept in good condition. The role of the makers in supporting improved quality in clinical laboratory tests will be expected.
Yoshimoto
A
A
Kotobiken Medical Laboratory, Biken Central Lab., Tsukuba.
D002096:C-Peptide / Q000652:urine*; D006801:Humans; D011786:Quality Control; D011863:Radioimmunoassay / Q000592:standards*; D011933:Reagent Kits, Diagnostic / Q000592:standards*
D002096:C-Peptide; D011933:Reagent Kits, Diagnostic