Malignant glioma of the optic chiasm eight years after radiotherapy for prolactinoma.
A 41-year-old man had rapidly progressive visual loss caused by a malignant glioma that developed in the optic chiasm eight years after radiation therapy for a recurrent prolactinoma. Radiation-induced glioma should be considered as a cause of progressive visual loss in patients who have received irradiation in the region of the sella turcica.
Hufnagel
T J
TJ
Section of Neuropathology, Yale University School of Medicine, New Haven, Conn 06510.
Kim
J H
JH
Lesser
R
R
Miller
J M
JM
Abrahams
J J
JJ
Piepmeier
J
J
Manuelidis
E E
EE
D000328:Adult; D001766:Blindness / Q000209:etiology*; D003390:Cranial Nerve Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D005910:Glioma / Q000150:complications / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000150:complications; D009897:Optic Chiasm / Q000473:pathology; D010911:Pituitary Neoplasms / Q000532:radiotherapy*; D015175:Prolactinoma / Q000532:radiotherapy*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014794:Visual Fields