title: Total parathyroidectomy with forearm autograft for secondary hyperparathyroidism in chronic renal failure.
abstract: One hundred twenty-eight patients with chronic renal failure and secondary hyperparathyroidism underwent total parathyroidectomy with forearm autograft. Postoperative clinical improvement was remarkable. In all cases, the grafted tissue functioned well, and reimplantation of the cryopreserved parathyroid tissues was unnecessary. Intact 1-84 parathyroid hormone was more sensitive than C-terminal parathyroid hormone in parathyroid hormone level (PTH) gradient assays of grafted and nongrafted forearm. The study of hypocalcemia was also helpful in obtaining more distinct PTH gradients. Five of 119 patients had supernumerary parathyroid glands (4.2%), which preoperative noninvasive image diagnosis of parathyroid glands was helpful in detecting.
authors.affiliation: Department of Surgery II, Nagoya University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Takagi
authors.forename: Y
authors.initials: Y
authors.lastname: Tominaga
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: A
authors.initials: A
authors.lastname: Orihara
authors.forename: N
authors.initials: N
authors.lastname: Yamada
authors.forename: M
authors.initials: M
authors.lastname: Kawai
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: N
authors.initials: N
authors.lastname: Taira
authors.forename: T
authors.initials: T
authors.lastname: Kano
mesh_terms: D000328:Adult; D005260:Female; D005542:Forearm; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000097:blood / Q000209:etiology / Q000601:surgery*; D006996:Hypocalcemia / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications / Q000601:surgery*; D008297:Male; D008722:Methods; D008875:Middle Aged; D010280:Parathyroid Glands / Q000002:abnormalities / Q000637:transplantation*; D010281:Parathyroid Hormone / Q000097:blood; D011183:Postoperative Complications / Q000209:etiology; D012008:Recurrence; D012086:Reoperation
chemical_list: D010281:Parathyroid Hormone