title: Effect of glycerol treatment on pulmonary lipid metabolism in mice.
abstract: In this study, we demonstrated that glycerol treatment caused the alterations of pulmonary lipid compositions in ddY mice. The increases of total phospholipid (TPL), diacylglyceride (DG), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) + phosphatidylglycerol (PG) contents in the lung were observed by oral administration of 5% glycerol in drinking water for 2 weeks. However, other pulmonary lipid components measured in this study were almost unchanged by this treatment. These results suggest that glycerol treatment might induce changes of pulmonary lipid metabolism in mice.
authors.affiliation: Department of Pathology, Yokohama City University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yano
authors.forename: N
authors.initials: N
authors.lastname: Nagahara
authors.forename: H
authors.initials: H
authors.lastname: Kitamura
authors.forename: M
authors.initials: M
authors.lastname: Kanisawa
mesh_terms: D000818:Animals; D004075:Diglycerides / Q000378:metabolism; D005990:Glycerol / Q000494:pharmacology*; D050356:Lipid Metabolism; D008168:Lung / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051379:Mice; D010713:Phosphatidylcholines / Q000378:metabolism; D010714:Phosphatidylethanolamines / Q000378:metabolism; D010715:Phosphatidylglycerols / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism
chemical_list: D004075:Diglycerides; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010715:Phosphatidylglycerols; D010743:Phospholipids; D005990:Glycerol