title: Tissue characterization of benign brain tumors: use of NMR-tissue parameters.
abstract: To evaluate the potentials of NMR tissue parameters for tissue characterization we investigated 68 patients with benign brain tumors. Tissue parameters were accurately measured by a recently developed interlaced triple sequence. Each individual tumor was characterized by a set of three numbers (relaxation times T1 and T2 and proton density Rho). Different tumors exhibited significant overlaps of the three tissue parameters. Therefore a reliable prediction of the histological diagnosis based on the quantitative analysis of tissue parameters alone was not possible. T2-prolongation correlated well with water content and "regressive changes" in meningiomas and neuromas.
authors.affiliation: Institut für klinische Strahlenkunde, Klinikum der Johannes Gutenberg Universität, Mainz, F.R.G.
authors.forename: M
authors.initials: M
authors.lastname: Just
authors.forename: H P
authors.initials: HP
authors.lastname: Higer
authors.forename: M
authors.initials: M
authors.lastname: Schwarz
authors.forename: J
authors.initials: J
authors.lastname: Bohl
authors.forename: G
authors.initials: G
authors.lastname: Fries
authors.forename: P
authors.initials: P
authors.lastname: Pfannenstiel
authors.forename: M
authors.initials: M
authors.lastname: Thelen
mesh_terms: D000236:Adenoma / Q000175:diagnosis; D001834:Body Water; D001921:Brain / Q000033:anatomy & histology; D001932:Brain Neoplasms / Q000175:diagnosis*; D003397:Craniopharyngioma / Q000175:diagnosis; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008579:Meningioma / Q000175:diagnosis; D008961:Models, Structural; D009464:Neuroma, Acoustic / Q000175:diagnosis; D010911:Pituitary Neoplasms / Q000175:diagnosis