[Inhibition of UV-induced accumulation of lipid peroxides by melanins and ommochromes].
The effect of screening pigments--melanin and ommochromes--on the UV-induced accumulation of lipid hydroperoxides by cardiolipin was studied. It was shown that the time dependence of lipid hydroperoxide accumulation at different UV irradiation intensities is linear. Addition of melanin or ommochromes results in a significant decrease of the lipid hydroperoxide accumulation rate. The kinetic curve rapidly reaches the saturation values, which is suggestive of intensive chemical inhibition of the reaction. The screens transmitting UV irradiation in the same degree as do melanin and ommochromes have a far less pronounced inhibiting effect. The inhibitory mechanism of screening pigments based on their antiradical activity is discussed.
Pustynnikov
M G
MG
Dontsov
A E
AE
D000818:Animals; D002308:Cardiolipins / Q000378:metabolism / Q000528:radiation effects; D007700:Kinetics; D008054:Lipid Peroxides / Q000037:antagonists & inhibitors* / Q000378:metabolism / Q000528:radiation effects; D008543:Melanins / Q000494:pharmacology*; D010640:Phenothiazines / Q000494:pharmacology*; D010860:Pigments, Biological / Q000494:pharmacology*; D014466:Ultraviolet Rays
D002308:Cardiolipins; D008054:Lipid Peroxides; D008543:Melanins; D010640:Phenothiazines; D010860:Pigments, Biological; C002772:ommochrome
Ingibirovanie UF-indutsirovannoĭ akkumuliatsii lipidnykh gidroperoksidov melaninami i ommokhromami.