Suggestively increased rate of infant death in children of fra(X) positive mothers.
A review of the Leuven data on the fragile X syndrome indicates that sudden infant death is frequently observed in the progeny of obligate female carriers. This observation may be another indication of a central nervous dysfunction in infants with this type of X-linked mental retardation.
Fryns
J P
JP
Department of Pathology, University of Leuven, Belgium.
Moerman
P
P
Gilis
F
F
d'Espallier
L
L
Van den Berghe
H
H
D002490:Central Nervous System / Q000503:physiopathology; D005260:Female; D005600:Fragile X Syndrome / Q000150:complications / Q000235:genetics* / Q000503:physiopathology; D006579:Heterozygote; D006801:Humans; D007223:Infant; D008297:Male; D011247:Pregnancy; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D013398:Sudden Infant Death / Q000209:etiology / Q000235:genetics* / Q000503:physiopathology