title: Preparation and physicochemical properties of uracil derivatives with potential biological activity.
abstract: The characterization of mono- and dimethylated 5-substituted uracils was re-examined. Analysis of their physicochemical properties (pKa, U.V., delta 1H-N.M.R.) affords insight into the structural characteristics of 5-substituted uracil alkylated at the ring nitrogens.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università di Modena, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Pecorari
authors.forename: G
authors.initials: G
authors.lastname: Vampa
authors.forename: A
authors.initials: A
authors.lastname: Albasini
authors.forename: M
authors.initials: M
authors.lastname: Rinaldi
authors.forename: M
authors.initials: M
authors.lastname: Melegari
authors.forename: M P
authors.initials: MP
authors.lastname: Costi
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014498:Uracil / Q000031:analogs & derivatives* / Q000032:analysis
chemical_list: D014498:Uracil