16-Deethylindanomycin (A83094A), a novel pyrrole-ether antibiotic produced by a strain of Streptomyces setonii. Taxonomy, fermentation, isolation and characterization.
16-Deethylindanomycin (A83094A) is a novel pyrrole-ether antibiotic produced by a strain of Streptomyces setonii. The antibiotic, which is structurally similar to indanomycin (X-14547A), is active in vitro against Gram-positive bacteria as well as coccidia.
Larsen
S H
SH
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.
Boeck
L D
LD
Mertz
F P
FP
Paschal
J W
JW
Occolowitz
J L
JL
D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification*; D003044:Coccidia / Q000187:drug effects; D005285:Fermentation; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007192:Indenes / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology; D051379:Mice; D011714:Pyrans / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology; D013302:Streptomyces / Q000145:classification / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D007192:Indenes; D011714:Pyrans; C057554:16-deethylindanomycin