title: Glucose-6-phosphate dehydrogenase variants and their frequency in Guangdong, China.
abstract: Erythrocyte glucose-6-phosphate dehydrogenase (G6PD) was characterized in blood samples obtained from 97 randomly selected males with enzyme deficiency from various regions of Guangdong Province, China. Nine new variants (Gd Kaiping, Gd Boluo, Gd Huiyang, Gd Gaomin, Gd Qing-Baijiang, Gd Gaozhou, Gd Huazhou, Gd Nanhai, and Gd Guangzhou) were identified. Of the 31 variants found in this province, Gd Kaiping, Gd Taiwan-Hakka, Gd Haad Yai, Gd Haad Yai-like and Gd Huiyang occurred most frequently. The frequency of each variant was calculated. The results demonstrated that the genetic heterogeneity of G6PD deficiency was high in this area.
authors.affiliation: Department of Medical Genetics, Sun Yat Sen University of Medical Sciences, Guangzhou, The People's Republic of China.
authors.forename: C S
authors.initials: CS
authors.lastname: Du
authors.forename: Y K
authors.initials: YK
authors.lastname: Xu
authors.forename: X Y
authors.initials: XY
authors.lastname: Hua
authors.forename: Q L
authors.initials: QL
authors.lastname: Wu
authors.forename: L B
authors.initials: LB
authors.lastname: Liu
mesh_terms: D002681:China; D004912:Erythrocytes / Q000201:enzymology; D005787:Gene Frequency; D005954:Glucosephosphate Dehydrogenase / Q000097:blood / Q000235:genetics*; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics*; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic
chemical_list: D005954:Glucosephosphate Dehydrogenase