A new microsurgical model for the study of carcinogenesis in colonic urinary diversion in rats.
A new rat model is presented to study the carcinogenesis in colonic urinary diversion. Surgical techniques performed on humans are simulated by microsurgery. The altered metabolism--hyperchloraemic acidosis--is taken into consideration. It seems to be an important co-factor for the carcinogenesis.
Miersch
W D
WD
Department of Urology, University of Bonn, FRG.
D000138:Acidosis / Q000150:complications; D000230:Adenocarcinoma / Q000209:etiology*; D000818:Animals; D002712:Chlorides / Q000097:blood; D012809:Colon, Sigmoid / Q000601:surgery; D003110:Colonic Neoplasms / Q000209:etiology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014547:Urinary Diversion / Q000009:adverse effects*; D014567:Urography
D002712:Chlorides