Combination chemotherapy of Echinococcus granulosus--in vitro studies.
Both benzimidazole carbamates and isoquinoline compounds have activity against protoscoleces of Echinococcus granulosus in culture in vitro; combinations of albendazole sulphoxide and praziquantel are more effective than either agent alone.
Taylor
D H
DH
Department of Surgery, University Hospital, Nottingham, UK.
Morris
D L
DL
Richards
K S
KS
D015766:Albendazole / Q000031:analogs & derivatives*; D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004443:Echinococcosis / Q000188:drug therapy*; D011223:Praziquantel / Q000627:therapeutic use*
D001562:Benzimidazoles; D011223:Praziquantel; D015766:Albendazole; C027186:albendazole sulfoxide