Tetracycline resistance and TetM in oral anaerobic bacteria and Neisseria perflava-N. sicca.
Tetracycline-resistant organisms isolated from six patients with periodontal disease included Bacteroides spp., Eubacterium spp., Fusobacterium nucleatum, Neisseria perflava-N. sicca, Peptostreptococcus anaerobius, Veillonella parvula, and facultative streptococci. All but the Bacteroides spp. and Eubacterium spp. hybridized with the TetM determinant. An additional 417 bacterial strains were screened, and 4% of both the oral streptococci and the Fusobacterium spp. hybridized with the TetM probe.
Roberts
M C
MC
Department of Pathobiology, University of Washington, Seattle 98195.
Moncla
B J
BJ
D000328:Adult; D001421:Bacteria, Anaerobic / Q000187:drug effects* / Q000235:genetics; D015139:Blotting, Southern; D004269:DNA, Bacterial / Q000235:genetics; D005798:Genes, Bacterial; D006801:Humans; D009343:Neisseria / Q000187:drug effects* / Q000235:genetics; D009693:Nucleic Acid Hybridization; D010514:Periodontal Pocket / Q000382:microbiology*; D010518:Periodontitis / Q000382:microbiology*; D013752:Tetracycline / Q000494:pharmacology; D013753:Tetracycline Resistance / Q000235:genetics*
D004269:DNA, Bacterial; D013752:Tetracycline