Treatment of Fasciola hepatica infection in horses with triclabendazole.
Thirteen thoroughbred foals with an adult infection and a presumed immature infection with Fasciola hepatica were treated with 12 mg triclabendazole/kg bodyweight. The absence of eggs from samples of faeces examined at intervals up to 110 days after treatment showed that all the animals were cured. In a second trial the same dose of triclabendazole cured 11 of 12 foals whereas nitroxynil at 7 mg/kg cured only six of 12 foals. No side effects were observed after treatment.
Rubilar
L
L
Department of Veterinary Medicine, University of Concepcion, Chile.
Cabreira
A
A
Giacaman
L
L
D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D005210:Fasciola hepatica; D005211:Fascioliasis / Q000188:drug therapy / Q000662:veterinary*; D005243:Feces / Q000469:parasitology; D006734:Horse Diseases / Q000188:drug therapy* / Q000469:parasitology; D006736:Horses; D009611:Nitroxinil / Q000627:therapeutic use; D010270:Parasite Egg Count / Q000662:veterinary; D000077682:Triclabendazole
D000871:Anthelmintics; D001562:Benzimidazoles; D000077682:Triclabendazole; D009611:Nitroxinil