title: Changes of contact phase proteins during haemodialysis.
abstract: Functional and immunological activities of factors XII and XI, Prekallikrein, high molecular weight kininogen and C-1-esterase inhibitor were studied in eight patients before, during and after haemodialysis. During and after dialysis sessions a significant decrease in the functional activities of Prekallikrein and high molecular weight kininogen (p less than 0.05) could be detected, whereas their immunological levels did not change. Furthermore C-1-esterase inhibitor increased after dialysis (p less than 0.05). These results indicate activation of the kinin system during haemodialysis.
authors.affiliation: Division of Haematology, University Hospital, Salamanca, Spain.
authors.forename: V
authors.initials: V
authors.lastname: Vicente
authors.forename: A
authors.initials: A
authors.lastname: Alegre
authors.forename: I
authors.initials: I
authors.lastname: Alberca
authors.forename: A
authors.initials: A
authors.lastname: Lopez Borrasca
authors.forename: J R
authors.initials: JR
authors.lastname: Gomez
authors.forename: J F
authors.initials: JF
authors.lastname: Macias
mesh_terms: D000328:Adult; D000368:Aged; D001780:Blood Coagulation Tests; D001798:Blood Proteins / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*
chemical_list: D001798:Blood Proteins