title: [Treatment of head and neck cancer with twice-a-day fractionation].
abstract: Fifty patients with locally advanced head and neck cancer were treated with twice-a-day fractionation (1.0-1.5 Gy 2 times daily, 5 days per week). These patients consist of 12 cases of thyroid cancer, 23 of hypopharynx cancer, 7 of cancer of the oral cavity, 6 of oropharynx cancer and 2 of other sites. Total delivered dose was 21-73 Gy in 10-74 days. In respect of thyroid cancer, 2 cases of 3 with papillo-follicular carcinoma, 1 of 1 with small cell carcinoma and 3 of 8 with giant cell carcinoma were locally controlled. Patients of hypopharyngeal carcinoma treated with multifractionated radiotherapy combined with or without surgery revealed good prognosis (91% of T1 + T2, 100% of T3 + T4 at 2 years). Patients with cancer of the oral cavity or oropharynx, however, had poor prognosis.
authors.affiliation: Dept. of Radiology, Osaka Univ. School of Med.
authors.forename: K
authors.initials: K
authors.lastname: Nishiyama
mesh_terms: D000368:Aged; D005260:Female; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000532:radiotherapy; D011379:Prognosis; D011878:Radiotherapy / Q000379:methods*; D011879:Radiotherapy Dosage; D013964:Thyroid Neoplasms / Q000532:radiotherapy