[Indices of lipid free-radical oxidation and of antiradical protection of the brain--the neurochemical correlates of the development of the general adaptation syndrome].
The stage of rat long-term adaptation to chronic emotional-pain stress is characterized by an increase of superoxide dismutase brain activity and superoxide-scavenging blood serum activity, accumulation of fluorescent products of free-radical oxidation, reduction of phospholipids and cholesterin contents in the brain lipid extracts. In the process of prolonged adaptation to the continuing chronic emotional-pain stress three periods are singled out, each of which with a definite correlation of characteristics of vegetative functions, behaviour, intensity of free-radical oxidation and antiradical defence.
Guliaeva
N V
NV
Levshina
I P
IP
Obidin
A B
AB
D000222:Adaptation, Physiological; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002908:Chronic Disease; D005609:Free Radicals; D005790:General Adaptation Syndrome / Q000209:etiology / Q000378:metabolism*; D006973:Hypertension / Q000503:physiopathology; D050356:Lipid Metabolism; D008297:Male; D010084:Oxidation-Reduction; D010146:Pain / Q000503:physiopathology; D051381:Rats; D013312:Stress, Physiological / Q000378:metabolism*; D013315:Stress, Psychological / Q000503:physiopathology; D013482:Superoxide Dismutase / Q000378:metabolism
D005609:Free Radicals; D013482:Superoxide Dismutase
Pokazateli svobodnoradikal'nogo okisleniia lipidov i antiradikal'noĭ zashchity mozga--neĭrokhimicheskie korreliaty razvitiia obshchego adaptatsionnogo sindroma.