title: The complete sequence of a chicken-muscle cDNA encoding the acidic ribosomal protein P1.
abstract: We have isolated and sequenced a complete cDNA encoding the acidic phosphoprotein P1 from chicken. The analysis of the deduced protein sequence and its comparison with the known sequence of P proteins from human, rat and Artemia salina indicates that the central, alanine-rich region of these proteins was probably generated by internal duplications of the gene followed by modifications within each repeat. This observation explains the length heterogeneity and sequence divergence of this particular region when compared with the highly conserved structure of the remaining segments of the protein.
authors.affiliation: Departamento de Bioquimica, Universidade de Sao Paulo, Brazil.
authors.forename: J A
authors.initials: JA
authors.lastname: Ferro
authors.forename: F C
authors.initials: FC
authors.lastname: Reinach
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001156:Artemia; D001483:Base Sequence; D002645:Chickens; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics* / Q000302:isolation & purification; D005796:Genes; D006801:Humans; D008969:Molecular Sequence Data; D009132:Muscles / Q000378:metabolism*; D009693:Nucleic Acid Hybridization; D010750:Phosphoproteins / Q000235:genetics*; D051381:Rats; D012269:Ribosomal Proteins; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
chemical_list: D010750:Phosphoproteins; D012269:Ribosomal Proteins; C035690:ribosomal phosphoprotein P1; D004247:DNA