[Comparative studies of bronchial secretion in children with chronic, nontuberculous lung diseases. 1. Methodico-technical studies of secretion collection and interpretation of the results].
The aim of the present study was to estimate different proteins in 166 bronchial secretions from 63 children with chronic nontuberculous lung diseases. In a first publication some methodological problems as the age of patients, the position of the bronchoscope, the bronchoscopic and bronchographic situation resp. and the mode of extraction are analysed. With increasing age the concentration of sIgA is elevated - in contrast to the IgG concentration. Only in severe diseases albumin declines with increasing age. Some variations in the concentration of proteins have been observed in relation to the position of the bronchoscope and in regard to a repeated extraction of bronchial secretions. No important differences in the concentration of proteins have been found in secretions obtained during diverse days. The different protein patterns in the bronchial secretions could be explained only partly by variations in the course of diseases.
Stelzner
A
A
Zentralinstitut für Midrobiologie und experimentelle Therapie der AdW der DDR, Jena.
Lehnert
U
U
Groh
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A
D000293:Adolescent; D000367:Age Factors; D000418:Albumins / Q000032:analysis; D001980:Bronchi / Q000032:analysis* / Q000276:immunology / Q000378:metabolism; D001999:Bronchoscopy; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D008171:Lung Diseases / Q000276:immunology / Q000378:metabolism*; D011506:Proteins / Q000032:analysis*; D013048:Specimen Handling
D000418:Albumins; D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G; D011506:Proteins
Vergleichende Bronchialsekretuntersuchungen bei Kindern mit chronischen, nichttuberkulösen Lungenerkrankungen. 1. Mitteilung: Methodisch-technische Untersuchungen zur Sekretgewinnung und Interpretation der Befunde.