[Hypolipidemic effect of the new diprophylline derivative, [2-hydroxy-3-(theophylline-7-ol] propyl ester of 4-benzylhydroxybenzoic acid].
A new derivative of diprophylline--[2-hydroxy-3(theophylline-7-ol)] propyl ester 4-benzyloxybenzoic acid was shown to decrease the content of cholesterol and of atherogenic lipoproteins in blood serum of hyperlipidemic guinea pigs. In blood serum of rabbits the new substance studied decreased cholesterol, free fatty acids and malonic dialdehyde concentrations.
Ryzhenkov
V E
VE
Chistiakova
A M
AM
Wójcicki
J
J
Samochowiec
L
L
Daday
R
R
D000818:Animals; D002994:Clofibrate / Q000494:pharmacology; D004036:Diet, Atherogenic; D004400:Dyphylline / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000633:toxicity; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006168:Guinea Pigs; D000960:Hypolipidemic Agents / Q000494:pharmacology* / Q000633:toxicity; D008055:Lipids / Q000097:blood; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D011817:Rabbits; D013806:Theophylline / Q000031:analogs & derivatives*
D005230:Fatty Acids, Nonesterified; D000960:Hypolipidemic Agents; D008055:Lipids; D004400:Dyphylline; D008315:Malondialdehyde; C057857:4-benzylhydroxybenzoic acid 2-hydroxy-3-(theophylline-7-ol)propyl ester; D013806:Theophylline; D002994:Clofibrate
Gipolipidemicheskoe deĭstvie novogo proizvodnogo diprofillina [2-gidroksi-3-(teofillin-7-il)] propilovogo éfira 4-benziloksibenzoĭnoĭ kisloty.