title: Radioisotope evidence of varying transit of solid food in gastrectomized patients with and without dumping syndrome.
abstract: Of 29 Billroth II gastrojejunostomy patients studied by scintigraphy, 11 were dumpers and 18 were non-dumpers; of 20 controls, 11 were patients with different gastric complaints and 9 volunteers with no history of gastrointestinal pathology. The tracer used was human albumin microspheres labelled with 99mTc, mixed thoroughly with a fresh scrambled egg, cooked as an omelet and eaten as a sandwich with white toasted bread. The transit and emptying of the radiolabelled meal in the gastric and derivative loop areas were followed with gamma camera 90-120 min. In the dumpers half-emptying times were significantly shorter than in the controls; in the non-dumpers they were even shorter. Dynamic selective analysis of the radiolabelled food transit through derivative afferent and efferent loops showed, on the other hand, different patterns for the two groups of gastroresected patients: the progression of propulsive waves was very irregular and constantly hyperperistaltic only in the dumpers.
authors.affiliation: Servizio di Medicina Nucleare, Ospedale Regionale, Treviso, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Palermo
authors.forename: F
authors.initials: F
authors.lastname: Boccaletto
authors.forename: M
authors.initials: M
authors.lastname: Magalini
authors.forename: G
authors.initials: G
authors.lastname: Chiara
authors.forename: T
authors.initials: T
authors.lastname: Tommaseo
authors.forename: L
authors.initials: L
authors.lastname: Dapporto
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D004377:Dumping Syndrome / Q000503:physiopathology*; D005260:Female; D005743:Gastrectomy; D005746:Gastric Emptying; D005772:Gastrointestinal Transit; D006801:Humans; D008297:Male; D008875:Middle Aged; D013668:Technetium Tc 99m Aggregated Albumin / Q000008:administration & dosage
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin