title: Eyelid pigment implantation: early and late histopathology.
abstract: Full-thickness sections of upper and lower eyelids were obtained from patients who had eyelid pigment implantation performed by one surgeon. These four patients represented eyelid pigment implantation at varying postoperative stages ranging from 6 months to 4 years. Light microscopic evaluation revealed pigment within dermis and superficial orbicularis muscle. Light and electron microscopic evaluation revealed the vast majority of the pigment to be located intracellularly, primarily within macrophages. No foreign-body reaction was seen around the implanted material. Electron probe analysis of the pigment showed only the presence of iron. Analysis of the unused pigment revealed small amounts of silica and magnesium. These substances could not be identified by electron probe analysis in the eyelid tissues.
authors.affiliation: LSU Eye Center, New Orleans, La. 70112-2234.
authors.forename: D E
authors.initials: DE
authors.lastname: Wolfley
authors.forename: K J
authors.initials: KJ
authors.lastname: Flynn
authors.forename: J
authors.initials: J
authors.lastname: Cartwright
authors.forename: J A
authors.initials: JA
authors.lastname: Tschen
mesh_terms: D000328:Adult; D001706:Biopsy; D004577:Electron Probe Microanalysis; D004954:Esthetics; D005069:Evaluation Studies as Topic; D005143:Eyelids / Q000032:analysis / Q000473:pathology* / Q000601:surgery; D005260:Female; D005290:Ferric Compounds; D006801:Humans; D008875:Middle Aged; D010860:Pigments, Biological; D019736:Prostheses and Implants; D013518:Surgery, Plastic; D013997:Time Factors
chemical_list: D005290:Ferric Compounds; D010860:Pigments, Biological; C000499:ferric oxide