title: Effects of maternal cocaine abuse on the neonatal auditory system.
abstract: Eighteen neonates born to cocaine-abusing mothers were tested for peripheral and brainstem auditory dysfunction using auditory brainstem responses (ABR). Their data were compared to ABRs from 18 normal neonates. The ABR data were analyzed to determine if ABR parameters were abnormal in neonates born to cocaine-abusing mothers in comparison to normal neonates. ABRs from neonates exposed to maternal cocaine abuse show prolonged interpeak latencies and prolonged absolute latencies. These abnormalities indicate neurologic impairment or dysfunction that warrants further audiologic and neurologic follow-up.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Southern California School of Medicine, Los Angeles 90033.
authors.forename: L
authors.initials: L
authors.lastname: Shih
authors.forename: B
authors.initials: B
authors.lastname: Cone-Wesson
authors.forename: B
authors.initials: B
authors.lastname: Reddix
mesh_terms: D001300:Audiometry, Evoked Response; D001306:Auditory Pathways / Q000187:drug effects; D001309:Auditory Threshold / Q000187:drug effects; D001933:Brain Stem / Q000187:drug effects*; D003042:Cocaine / Q000009:adverse effects*; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced*; D006801:Humans; D007231:Infant, Newborn; D009357:Neonatal Abstinence Syndrome / Q000209:etiology*; D011930:Reaction Time / Q000187:drug effects; D012307:Risk Factors
chemical_list: D003042:Cocaine