title: Enkephalin-like immunoreactive principal ganglion cells and nerve fibres in the inferior mesenteric ganglion of the cat.
abstract: The occurrence and distribution of methionine-enkephalin (ME), leucine-enkephalin (LE) and methionine-enkephalin-Arg6-Gly7-Leu8 (MERGL)-like (LI) immunoreactive material in the inferior mesenteric ganglion (IMG) of the cat were studied by immunohistochemical techniques using the peroxidase-antiperoxidase method. Numerous ME-Li, LE-Li and MERGL-Li immunoreactive fibres with the same distribution pattern were observed. They were varicose and often surrounded closely neighbouring unlabelled ganglion cell bodies. Sometimes they ran in strands between ganglion cells. ME-Li immunoreactive material was detected in a number of cell bodies, the diameter of which was similar to that of unlabelled principal ganglion cell bodies, and which were probably Enk-Li-containing principal ganglion cells. These immunoreactive cells were often surrounded by ME-Li immunoreactive fibres. No LE-Li or MERGL-Li immunoreactive ganglion cell bodies were observed. The presence of ME-Li immunoreactive principal ganglion cells raises the possibility that the Enk-Li immunoreactive fibres present in the IMG may have a prevertebral ganglionic source. The possibility that the Enk-Li material present in nerve fibres might be derived from preproenkephalin-A was suggested by the occurrence of MERGL-Li immunoreactivity.
authors.affiliation: Département de Physiologie et Neurophysiologie, C.N.R.S. UA 205, Faculté des Sciences de Saint-Jérôme, Marseille, France.
authors.forename: M
authors.initials: M
authors.lastname: Balayadi
authors.forename: Y
authors.initials: Y
authors.lastname: Jule
authors.forename: A
authors.initials: A
authors.lastname: Cupo
mesh_terms: D000818:Animals; D002415:Cats; D004743:Enkephalin, Leucine / Q000032:analysis*; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives* / Q000032:analysis*; D005260:Female; D005728:Ganglia, Sympathetic / Q000166:cytology / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male
chemical_list: D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine; C033453:enkephalin-Met, Arg(6)-Gly(7)-Leu(8)-