title: Legionnaires' disease in the work environment: implications for environmental health.
abstract: Legionnaires' disease is a severe pneumonia caused by the bacterium Legionella pneumophila. Outbreaks of Legionnaire's disease have occurred in hotels, hospitals, and homes but had not been reported yet in the work environment. The authors report the occurrence of Legionnaires' disease in three employees of two industrial plants. The potable water in the two plants contained high numbers of Legionella pneumophila. Monoclonal antibody subtyping of environmental and patient isolates of L. pneumophila implicated one of the plants as the source for the disease. L. pneumophila was eradicated from this plant using acidic and caustic scale removers, calcium hypochlorite, and a biocide. A systematic approach to Legionnaires' disease in the work environment, a problem which can be expected to be recognized with increasing frequency, is presented.
authors.affiliation: Special Pathogens Section, Veterans Administration Medical Center, Pittsburgh, PA.
authors.forename: P W
authors.initials: PW
authors.lastname: Muraca
authors.forename: J E
authors.initials: JE
authors.lastname: Stout
authors.forename: V L
authors.initials: VL
authors.lastname: Yu
authors.forename: Y C
authors.initials: YC
authors.lastname: Yee
mesh_terms: D000911:Antibodies, Monoclonal; D004203:Disinfection / Q000379:methods; D005260:Female; D006801:Humans; D007875:Legionella / Q000302:isolation & purification; D007877:Legionnaires' Disease / Q000453:epidemiology* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology* / Q000517:prevention & control; D012698:Serologic Tests; D014871:Water Microbiology
chemical_list: D000911:Antibodies, Monoclonal