title: Acylureidoalkylphenylsulfonylureas with blood glucose lowering efficacy.
abstract: The structure and the synthesis of the blood-glucose lowering sulfonylurea glimepiride (Hoe 490) and of some analogues is described. The acylureido group of these compounds is prepared from lactams.
authors.affiliation: Hoechst Aktiengesellschaft, Frankfurt/Main, Fed. Rep. of Germany.
authors.forename: R
authors.initials: R
authors.lastname: Weyer
authors.forename: V
authors.initials: V
authors.lastname: Hitzel
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D007004:Hypoglycemic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D011817:Rabbits; D013453:Sulfonylurea Compounds / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; C057619:glimepiride