title: [Antibodies against structural proteins of carlaviruses in human and other mammals].
abstract: The study of four isolates of chrysanthemum B-virus (CVB) has shown the virus to have a single 40 Kd structural protein able to dissociate under the definite conditions forming the truncated (for 3 and 6 Kd) polypeptides having preserved their whole antigenic determinants. The human plasma is shown to contain antibodies reacting with the structural protein B-BX and, approximately 10 times weaker with the structural protein of another carlavirus, potato M-virus. Interaction of antibodies with CVB is found to take place due to F(ab)2 fragments. The analogous reaction with the proteins of other plant viruses or retroviruses has never been registered. Antibodies reacting with CVB protein are also present in the plasma of green monkey, rabbit, mouse and goat but in lesser quantities than in human plasma. Two possible explanations are proposed for the presented data, either immunization of mammalians by the protein or peptide containing its antigenic determinant, or the accidental coincidence of CVB antigenic determinant with some viral, bacterial or fungal determinant widespread in mammalians.
authors.forename: V A
authors.initials: VA
authors.lastname: Morozov
authors.forename: P O
authors.initials: PO
authors.lastname: Il'inskiĭ
authors.forename: K V
authors.initials: KV
authors.lastname: Il'in
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000918:Antibody Specificity; D003429:Cross Reactions; D006801:Humans; D015151:Immunoblotting; D010942:Plant Viruses / Q000235:genetics / Q000276:immunology*; D014764:Viral Proteins / Q000235:genetics / Q000276:immunology*; D015678:Viral Structural Proteins
chemical_list: D000914:Antibodies, Viral; D014764:Viral Proteins; D015678:Viral Structural Proteins
vernacular_title: Antitela k strukturnym belkam karlavirusov u cheloveka i drugikh mlekopitaiushchikh.