A modified rabbit ear chamber and an example of its application for intravital-microscopic study on acute effects of topical thermal stimulation.
A pre-existing plastic rabbit ear chamber was modified to be applicable for intravital-microscopic observations in pharmacological as well as pathophysiological studies on inflammation. The chamber consists of a base disk, a mica (or glass) cover-slip and a holder ring. The base disk has a round-table with a central protrusion in which a heat conductor of platinum wire is so implanted near the protrusion that thermal stimulation can be given to the regenerated tissue between the table and the coverslip.
Asano
M
M
Department of Physiological Hygiene, Institute of Public Health, Tokyo, Japan.
Ohkubo
C
C
Sasaki
A
A
D000818:Animals; D004423:Ear / Q000098:blood supply* / Q000293:injuries; D006358:Hot Temperature / Q000009:adverse effects*; D008833:Microcirculation / Q000293:injuries / Q000502:physiology; D011817:Rabbits; D014661:Vasoconstriction