title: Liposome-bound cyclosporine: retinal toxicity after intravitreal injection.
abstract: The retinal toxicity of intraocular liposome-bound cyclosporine was studied in albino rabbits by means of electrophysiology and histopathology. During a followup period of one month, no histopathological or electroretinographic changes were noted using concentrations of 100, 200 and 500 micrograms injected intravitreally.
authors.affiliation: LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans.
authors.forename: A A
authors.initials: AA
authors.lastname: Alghadyan
authors.forename: G A
authors.initials: GA
authors.lastname: Peyman
authors.forename: B
authors.initials: B
authors.lastname: Khoobehi
authors.forename: K R
authors.initials: KR
authors.lastname: Liu
mesh_terms: D000818:Animals; D003524:Cyclosporins / Q000008:administration & dosage / Q000633:toxicity*; D004337:Drug Carriers; D004594:Electrophysiology; D007267:Injections; D008081:Liposomes; D011817:Rabbits; D012160:Retina / Q000187:drug effects* / Q000473:pathology; D013997:Time Factors; D014822:Vitreous Body / Q000378:metabolism*
chemical_list: D003524:Cyclosporins; D004337:Drug Carriers; D008081:Liposomes