title: Cheiro-oral syndrome: does it have a specific localizing value?
abstract: A sensory disturbance limited to the hand or fingers and the corner of the mouth both on the same side constitutes the cheiro-oral syndrome (COS). Six patients with typical COS are described; in 5 of them a well-circumscribed lesion was found at different brain sites. Although this syndrome was formerly attributed to a parietal or thalamic lesion, a lesion at brainstem level also can cause COS. The pathogenetic explanation of this peculiar sensory symptom complex is a matter of debate and a new hypothesis is formulated. We advocate that when COS is encountered, especially if a history of migraine is lacking, a thorough neurological workup is called for.
authors.affiliation: Department of Neurology, St. Elisabeth Hospital, Tilburg, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Ten Holter
authors.forename: C
authors.initials: C
authors.lastname: Tijssen
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D001927:Brain Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D006225:Hand / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000503:physiopathology*; D009422:Nervous System Diseases / Q000209:etiology / Q000503:physiopathology; D012677:Sensation / Q000502:physiology*; D013577:Syndrome; D014057:Tomography, X-Ray Computed