Possible roles for pyruvate:ferredoxin oxidoreductase and thiol-dependent peroxidase and reductase activities in resistance to nitroheterocyclic drugs in Giardia intestinalis.
Smith
N C
NC
Bryant
C
C
Boreham
P F
PF
D000818:Animals; D004351:Drug Resistance; D005664:Furazolidone / Q000494:pharmacology*; D005872:Giardia / Q000187:drug effects / Q000201:enzymology*; D007658:Ketone Oxidoreductases / Q000378:metabolism*; D008795:Metronidazole / Q000494:pharmacology; D009593:Nitroimidazoles / Q000494:pharmacology*; D010088:Oxidoreductases / Q000378:metabolism*; D010544:Peroxidases / Q000378:metabolism*; D050743:Pyruvate Synthase; D013438:Sulfhydryl Compounds / Q000378:metabolism; D014011:Tinidazole / Q000494:pharmacology
D009593:Nitroimidazoles; D013438:Sulfhydryl Compounds; D014011:Tinidazole; D008795:Metronidazole; D005664:Furazolidone; D010088:Oxidoreductases; D010544:Peroxidases; C058652:thiol-dependent peroxidase; D007658:Ketone Oxidoreductases; D050743:Pyruvate Synthase