Calcium homeostasis in prepubertal diabetic children.
Many authors have described abnormalities of calcium homeostasis in type I diabetes mellitus, but data in the literature are conflicting. Consequently we studied calcium, phosphorus and magnesium (in serum and urine), parathyroid hormone, calcitonin and 25-hydroxyvitamin D (25-OHD) levels in 21 prepubertal diabetic patients and in 21 sex- and age-matched controls. We did not find any significant difference of all the aforementioned parameters between diabetics and controls. Also the value of 25-OHD was similar in diabetic and healthy subjects (24.33 +/- 6.04 vs 22.09 +/- 5.01 ng/ml). The results suggest that the principal parameters of calcium metabolism are normal in prepubertal diabetic children.
Verrotti
A
A
Clinica Pediatrica, Università di Chieti, Italy.
Blasetti
A
A
Tumini
S
S
Chiarelli
F
F
Morgese
G
G
D002116:Calcitonin / Q000097:blood; D002118:Calcium / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D006706:Homeostasis; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood; D008274:Magnesium / Q000378:metabolism; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000378:metabolism; D012016:Reference Values
D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D010758:Phosphorus; D002116:Calcitonin; D008274:Magnesium; D002118:Calcium