title: [Su-polysaccharide skin test and immunotherapy with OK-432 in postoperative gastric cancer--the effect of a splenectomy].
abstract: A SU-polysaccharide skin test (SU-PS test) has been employed and studied as a parameter for monitoring the immunological status of OK-432 treated patients who had undergone a curative gastrectomy for a gastric cancer in stages II and III. The median diameter of the erythema (SU-PS value) was found to have no relation to the number of lymphocytes and the serum protein level and was depressed by combined chemotherapy. The SU-PS value was significantly higher in patients not given a splenectomy than in patients who had undergone a patients splenectomy. The spleen is considered the essential organ to focus on in OK-432 immunotherapy.
authors.affiliation: Dept. of Surgery, Koseiren Takaoka Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Saito
authors.forename: H
authors.initials: H
authors.lastname: Kikkawa
authors.forename: H
authors.initials: H
authors.lastname: Bando
authors.forename: M
authors.initials: M
authors.lastname: Sakatoku
authors.forename: M
authors.initials: M
authors.lastname: Hirano
authors.forename: T
authors.initials: T
authors.lastname: Tatsuzawa
mesh_terms: D000368:Aged; D001688:Biological Products / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007167:Immunotherapy; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000627:therapeutic use*; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D011184:Postoperative Period; D012882:Skin Tests; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000276:immunology* / Q000601:surgery / Q000628:therapy; D013291:Streptococcus / Q000276:immunology*
chemical_list: D001688:Biological Products; D011135:Polysaccharides, Bacterial; D010844:Picibanil