title: Sialyltransferase activity in erythrocyte membranes and serum in patients with myotonic dystrophy.
abstract: Sialyltransferase activity was measured in erythrocyte membranes and in serum in patients with myotonic dystrophy and in matched healthy controls. The reason for assaying this enzyme was to study a possible mechanism behind a previously reported deficiency of glycoprotein-bound sialic acid in the erythrocyte membrane in patients with this disease. No significant differences in sialyltransferase activity with endogenous or different exogenous glycoprotein acceptors were found.
authors.affiliation: Department of Neurology, Karolinska Hospital, Stockholm, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Stibler
authors.forename: O
authors.initials: O
authors.lastname: Sydow
mesh_terms: D000293:Adolescent; D000328:Adult; D004910:Erythrocyte Membrane / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000201:enzymology*; D012799:Sialyltransferases / Q000097:blood*; D000094802:beta-D-Galactoside alpha 2-6-Sialyltransferase
chemical_list: D012799:Sialyltransferases; D000094802:beta-D-Galactoside alpha 2-6-Sialyltransferase