title: High resolution on-line analysis of cardiac action potentials using a Motorola 68000 microcomputer.
abstract: We have developed a microcomputer system for the instantaneous on-line analysis of cardiac action potentials (APs) based on a Motorola 68000 microprocessor and 50 kHz A/D converter. This system can accurately analyze APs from all parts of the heart, including the extremely fast upstrokes of APs from Purkinje fibers. Facilities for tabulation of results, production of hard-copy plots of APs, pooling of experimental data, and statistical analyses are available off-line. The routine use of this system in our laboratory has greatly increased the accuracy and throughput of these time-consuming experiments.
authors.affiliation: Department of Discovery Biology, Pfizer Central Research, Sandwich, Kent, UK.
authors.forename: R
authors.initials: R
authors.lastname: King
authors.forename: J
authors.initials: J
authors.lastname: Catlow
authors.forename: M
authors.initials: M
authors.lastname: Gwilt
authors.forename: A
authors.initials: A
authors.lastname: Higgins
mesh_terms: D000200:Action Potentials; D000818:Animals; D004285:Dogs; D004594:Electrophysiology / Q000295:instrumentation; D006321:Heart / Q000502:physiology*; D066298:In Vitro Techniques; D008838:Microcomputers; D011690:Purkinje Fibers / Q000502:physiology; D011817:Rabbits; D012849:Sinoatrial Node / Q000502:physiology; D012984:Software