[Correlation of progesterone and apoprotein B in pregnancy].
For the synthesis of progesterone the placenta uses cholesterol which is derived from low density lipoproteins (LDL). Apoprotein B (apo B) is the mediator for the uptake of LDL into the cell. This investigation was done to find relations between progesterone and apo B concentrations in the blood serum of pregnant women. 269 patients (8th to 41st week of pregnancy) were studied. Progesterone was estimated by radioimmunoassay, apo B by radial immunodiffusion. The concentration of apo B decreases from 8th/9th to 14th/15th week of pregnancy significantly, and this is followed by a continuous increase of the apo B concentration until parturition. The concentration of progesterone increases during pregnancy. The intermediate decrease after the 14th/15th week is to be seen in connection with the luteoplacental shift.
Seiler
E
E
Institut für Klinische Chemie der Medizinischen Akademie Carl Gustav Carus Dresden.
Woitke
A K
AK
Schollberg
K
K
Riehn
A
A
D001055:Apolipoproteins B / Q000097:blood*; D005260:Female; D005865:Gestational Age; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy / Q000097:blood*; D011374:Progesterone / Q000097:blood*
D001055:Apolipoproteins B; D011374:Progesterone
Untersuchungen über den Zusammenhang von Progesteron und Apoprotein B in der Schwangerschaft.