title: A new type of muscular dystrophy in two brothers: analysis by use of DNA probes suggests autosomal recessive inheritance.
abstract: X-chromosome-specific DNA probes were used to study a new type of muscular dystrophy (MD) presented by two boys in a family in which there was no previous history neuromuscular disease. Clinical investigations showed evidence of myogenic myopathyia, but its exact nature could not be established. The results of the DNA analysis exclude DMD, BMD and EMD. We suggest a probable autosomal recessive inheritance for the MD seen in this family.
authors.affiliation: Department of Medical Genetics, BMC, University of Uppsala, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Goonewardena
authors.forename: K H
authors.initials: KH
authors.lastname: Gustavson
authors.forename: I
authors.initials: I
authors.lastname: Gamstorp
authors.forename: N R
authors.initials: NR
authors.lastname: Lundström
authors.forename: U
authors.initials: U
authors.lastname: Pettersson
mesh_terms: D000293:Adolescent; D002648:Child; D015342:DNA Probes; D005808:Genes, Recessive; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D009136:Muscular Dystrophies / Q000235:genetics*; D010375:Pedigree; D014960:X Chromosome
chemical_list: D015342:DNA Probes