A comparison of GAD- and GABA-immunoreactive neurons in the first somatosensory area (SI) of the rat cortex.
Neurons immunoreactive for anti-glutamic acid decarboxylase (anti-GAD) and anti-gamma-aminobutyric acid (anti-GABA) were compared in adjacent sections from the rat somatosensory cortex (SI). GAD- and GABA-positive neurons in animals either treated or not treated with colchicine were found to occur at a ratio of 1:2. Measurement of areas of GAD- and GABA-immunoreactive neurons confirmed the presence of an 'exuberant' GABA-positive neuronal population not visualized by the GAD antiserum.
Spreafico
R
R
Department of Neurophysiology, Istituto Neurologico C. Besta, Milan, Italy.
De Biasi
S
S
Frassoni
C
C
Battaglia
G
G
D000818:Animals; D002452:Cell Count; D005968:Glutamate Decarboxylase / Q000378:metabolism*; D007150:Immunohistochemistry; D051381:Rats; D013003:Somatosensory Cortex / Q000166:cytology / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase