title: Primary immunodeficiency in Colombian children.
abstract: Eighty-three patients with diagnosis of immunodeficiency were studied, antibody deficiency disorders were the most common 74.6%, abnormalities of unspecific mechanisms in 13.3% and deficiencies of cell mediated immunity in 9.6% of patients. Selective IgA deficiency was the most common of the humoral defects, 28 patients, the others were IgM and IgG selectives deficiency. The mortality was 6%, specially in patients with cellular deficiency. Immunodeficiencies are one of most common genetic diseases, needing appropriate diagnosis, treatment and developing centers with advanced technology.
authors.affiliation: Universidad de Caldas, Facultad de Medicina, Departamento de Pediatría, Hospital Infantil Universitario, Manizales, Galdas, Colombia.
authors.forename: R M
authors.initials: RM
authors.lastname: Núñez
mesh_terms: D000361:Agammaglobulinemia / Q000453:epidemiology / Q000276:immunology; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000145:classification / Q000453:epidemiology* / Q000276:immunology; D007223:Infant; D008297:Male