title: [Frequent occurrences of an enlarged submandibular gland following interstitial irradiation therapy in patients with cancer of the tongue].
abstract: A submandibular gland enlargement produces complications in the diagnosis of a nodal metastasis during the follow-up period in patients who have been given interstitial irradiation therapy for their oral cancers. Thus, a retrospective study has been made of the records of such affected patients, to accumulate knowledge regarding the frequency, the time of appearance, and the symptoms leading to the gland enlargement. Among 155 cases of squamous cell carcinoma of the tongue, 73 cases were selected for this study by the following criteria: (1) the patients were free of metastatic adenopathy, (2) they had been interstitially irradiated, and, (3) they were followed-up without surgical treatment for more than 6 months after the radiotherapy. Gland enlargement was found to have developed in 70% of the studied patients, that is, in 49 of the 73 cases within 9 months after radiotherapy.
authors.affiliation: Dept. of Dental Radiology, School of Dent., Tokyo Medical & Dental Univ.
authors.forename: S
authors.initials: S
authors.lastname: Moriguchi
authors.forename: M
authors.initials: M
authors.lastname: Takeda
authors.forename: H
authors.initials: H
authors.lastname: Shibuya
authors.forename: T
authors.initials: T
authors.lastname: Okuyama
authors.forename: J
authors.initials: J
authors.lastname: Horiuchi
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects* / Q000379:methods; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D006984:Hypertrophy; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D009333:Neck; D011832:Radiation Injuries / Q000175:diagnosis / Q000453:epidemiology; D012189:Retrospective Studies; D013363:Submandibular Gland / Q000473:pathology*; D013997:Time Factors; D014062:Tongue Neoplasms / Q000473:pathology / Q000532:radiotherapy*