title: Direct identification of parameters in a mathematical model describing conduction through the atrioventricular node.
abstract: Function of the atrioventricular node is assessed during intracardiac electrophysiology study by relating the output intervals A2H2 and H1H2 to the input A1A2, where A and H are, respectively, atrial and His bundle electrograms recorded by catheter. The H1H2 curves have been previously deduced from a model describing the A2H2 curves. Because of presence in a few cases of different behaviour of A2H2 and H1H2, this study aimed to establish a more suitable model of H1H2 independently of A2H2 for the particular case of a single transmission pathway. The two models were compared by calculation of standard error of the estimate. As a first approximation, the deduced model may be sufficient. However, the standard error of the estimate was less with the direct algorithm, which is therefore the more suitable for further development, particularly for recognition and modelling of conduction over multiple pathways through the atrioventricular node.
authors.affiliation: Department of Cardiology, Flinders Medical Centre, Bedford Park, South Australia.
authors.forename: L
authors.initials: L
authors.lastname: Dorveaux
authors.forename: N
authors.initials: N
authors.lastname: Twidale
authors.forename: A
authors.initials: A
authors.lastname: Tonkin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001283:Atrioventricular Node / Q000502:physiology*; D006328:Cardiac Catheterization; D004566:Electrodes; D004594:Electrophysiology; D005260:Female; D006329:Heart Conduction System / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular