title: Prognosis of bladder cancer. III. The value of radical cystectomy in the management of invasive bladder cancer.
abstract: From January 1979 to June 1982, 141 consecutive patients with bladder transitional cell carcinoma were treated with a single stage lymphadenectomy plus radical cystectomy. The survival rate observed in our patients, based on the TNM classification, was comparable with that reported for other groups employing contemporary surgery. Survivorship for patients with deep invasive tumors was also estimated by breaking down the pT3 stage, and patients with tumor confined to the bladder wall (pT3a) were separately evaluated from those with tumor extended outside (pT3b). The results obtained with this subdivision showed that pT3a patients have almost the same survival rate as pT2 patients. From these results it is concluded that radical cystectomy is a satisfactory curative treatment of bladder cancer confined to the bladder wall, whatever the extension of the muscular involvement. Such considerations suggest that, in order to achieve a more objective analysis of the results after radical cystectomy for invasive bladder cancer, a modification of clinical staging is necessary. Moreover, a simplification of the classification methods should provide a better identification of the elements required to assess the prognosis and to improve treatment planning.
authors.affiliation: Department of Urology, University of Padua, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Pagano
authors.forename: S
authors.initials: S
authors.lastname: Guazzieri
authors.forename: W
authors.initials: W
authors.lastname: Artibani
authors.forename: T
authors.initials: T
authors.lastname: Prayer-Galetti
authors.forename: C
authors.initials: C
authors.lastname: Milani
authors.forename: P
authors.initials: P
authors.lastname: Bassi
authors.forename: A
authors.initials: A
authors.lastname: Garbeglio
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D001743:Urinary Bladder / Q000601:surgery*; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000601:surgery*; D014547:Urinary Diversion