[Production of transgenic rabbits and mice carrying the gene for bovine growth hormone].
The results of experiments on the transfer of bovine gene for growth hormone into mice and rabbits are presented. The gene was transferred by the technique of microinjection into the zygote. In all cases transgene in rabbits occurred to be changed. In two transgenic mice the bovine growth hormone gene represented some tandem arranged copies. One of the mice had accelerated growth. This phenotypic changes is found to be inheritable.
Gazarian
K G
KG
Andreeva
L E
LE
Serova
I A
IA
Tarantul
V Z
VZ
Kuznetsova
E D
ED
D000818:Animals; D030801:Animals, Genetically Modified / Q000235:genetics* / Q000254:growth & development; D002417:Cattle; D004247:DNA / Q000235:genetics*; D013006:Growth Hormone / Q000235:genetics*; D051379:Mice; D008822:Mice, Transgenic / Q000235:genetics* / Q000254:growth & development; D008845:Microinjections; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D011817:Rabbits
D013006:Growth Hormone; D004247:DNA
Poluchenie transgennykh krolikov i mysheĭ, soderzhashchikh gen gormona rosta byka.