title: [Colorectal cancer in Madagascar. A study of 81 cases diagnosed and treated at the Antananarivo General Hospital].
abstract: Colorectal adenocarcinoma are rare in Madagascar. Over a period of 8 years, such tumors were treated in the cancerology and surgery departments of Antananarivo. The low incidence and the relative young age at the time of diagnosis are comparable to observations made in other developing countries. Men represent 47 of the cases and women 34. On the average, patients were 52.3 years old (range: 23-78 years). The most frequent early symptoms are rectorrhagia (26 cases) for rectal cancer, abdominal pain (9 cases) and transit bowel disorders (9 cases) for colon cancer. Between the first symptom and diagnosis, the average delay is 8.5 months (range: 2 days-37 months). No risk factor was found. Thirteen patients did not receive any treatment, 8 were only submitted to radiotherapy and 60 were surgically treated with a curative intent in 26 cases, a palliative one in 32 cases and for diagnosis in 2 cases. Among the 63 tumors available for modified Dukes' classification of Astler-Coller, 9.5% are stage B1, 23.8% are stage B2, 11% are stage C1, 15.9% are stage C2 and 39.7% are stage D; there are no stage A. There is no epidemiological particularity for these cancers in Madagascar. The poor prognosis is probably mainly related to a lack of appropriate medical and surgical facilities.
authors.affiliation: Service de chirurgie IV, Hôpital J.-Ravoahangy-Adrianavalona, Madagascar.
authors.forename: T
authors.initials: T
authors.lastname: Pignon
authors.forename: V
authors.initials: V
authors.lastname: Andriamanday
authors.forename: M
authors.initials: M
authors.lastname: Ralantoarimihanta
authors.forename: A
authors.initials: A
authors.lastname: Rakotobe
authors.forename: J
authors.initials: J
authors.lastname: Randrianonimandimby
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008270:Madagascar; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012307:Risk Factors
vernacular_title: Les Cancers colorectaux à Madagascar. Etude à partir de 81 cas diagnostiqués et traités à l'hôpital Général d'Antananarivo.