title: Osteoporosis in Scheuermann's disease.
abstract: A prospective study was undertaken to evaluate osteoporosis in Scheuermann's disease. Ten consecutive untreated patients with thoracic Scheuermann's were studied. The mean age was 16 years, 1 month, and the mean kyphosis was 64 degrees. Osteoporosis was quantitated by single and dual photon absorptiometry. Seven age-, sex-, height-, and weight-matched subjects were used as controls. The mean bone mineral density (BMD) of the lumbar spine was 0.975, compared with 1.130 for the control group, significant at P less than 0.025. For patients with a kyphosis greater than 45 degrees, the BMD was 0.913, significant at P less than 0.005. The mean BMD of the femoral neck was 1.00, compared with 1.22, significant at P less than 0.005. For patients with a kyphosis greater than 45 degrees, the femoral neck BMD is 0.983, significant at P less than 0.005. The BMD of the radius by single photon absorptiometry was 0.689, compared with 0.748 in the controls, which was not significant. In patients with a kyphosis greater than 45 degrees, the BMD was 0.655, which is significant at P less than 0.01. A highly significant association exists between osteoporosis and Scheuermann's disease. Further investigation is indicated to determine the role of medical management in the treatment of these patients.
authors.affiliation: Department of Orthopedic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.
authors.forename: R A
authors.initials: RA
authors.lastname: Lopez
authors.forename: S W
authors.initials: SW
authors.lastname: Burke
authors.forename: D B
authors.initials: DB
authors.lastname: Levine
authors.forename: R
authors.initials: R
authors.lastname: Schneider
mesh_terms: D000293:Adolescent; D001842:Bone and Bones / Q000378:metabolism; D005272:Femur Neck / Q000378:metabolism; D006801:Humans; D007738:Kyphosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000378:metabolism; D008161:Lumbosacral Region; D008903:Minerals / Q000378:metabolism; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000209:etiology*; D011446:Prospective Studies; D011877:Radionuclide Imaging; D012544:Scheuermann Disease / Q000150:complications* / Q000378:metabolism; D013131:Spine / Q000000981:diagnostic imaging / Q000378:metabolism
chemical_list: D008903:Minerals