[Prospects for the use of monoclonal antibodies in Yersinia pestis].
Industrial production of plague monoclonal antibodies in mice BALB/c was shown possible. Precipitation of the immunoglobulins with caprylic acid provided the highest purity of the preparations. Maintenance of the specific activity by the monoclonal antibodies was stable. The immunoenzymatic conjugate and erythrocytic diagnosticum on the basis of the monoclonal antibodies are sensitive, specific and may be used in antiplague practice.
Temiralieva
G A
GA
Arakelian
I S
IS
Lukhnova
L Iu
LIu
Apsatarova
R A
RA
Kravchenko
N P
NP
D000818:Animals; D000911:Antibodies, Monoclonal / Q000302:isolation & purification; D006825:Hybridomas / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D015010:Yersinia pestis / Q000276:immunology*
D000911:Antibodies, Monoclonal
Perspektivy ispol'zovaniia monoklonal'nykh antitel k Yersinia pestis.