[Changes in the 13,14-dihydro-15-ketoprostaglandin F2alpha and oxytocin level in the 1st trimester following beta-sympathomimetic and intracervical prostaglandin E2 gel administration].
3 ml tylose gel containing 500 micrograms PGE2 was injected into the cervical canal of 23 patients prior to first trimester abortion. 11 patients received 5 mg fenoterol orally before the PGE2-gel application and 12 patients a placebo tablet. The PGFM and oxytocin concentrations in plasma were determined radioimmunologically. The results showed the dominant role of elevated PGFM levels in the clinical prevalence of pain during induced abortion.
Osmers
R
R
Universitätsfrauenklinik Göttingen.
Goeschen
K
K
Fuchs
A R
AR
Dennemark
N
N
D000028:Abortion, Induced; D000328:Adult; D002584:Cervix Uteri / Q000187:drug effects; D015237:Dinoprost / Q000031:analogs & derivatives* / Q000097:blood; D015232:Dinoprostone; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage*; D005782:Gels; D006801:Humans; D010121:Oxytocin / Q000097:blood*; D011247:Pregnancy; D011292:Premedication; D014590:Uterine Contraction / Q000187:drug effects
D005782:Gels; D005280:Fenoterol; C008228:15-keto-13,14-dihydroprostaglandin F2alpha; D010121:Oxytocin; D015237:Dinoprost; D015232:Dinoprostone
Veränderungen der PGFM- und Oxytocin-Spiegel im 1. Trimenon unter Einfluss von Beta-Sympathikomimetika nach intrazervikaler Prostaglandin-E2-Gel-Applikation.