[Detection of N-acylethanolamine phospholipids in neuroblastoma C1300 cells].
Phospholipids with high chromatographic mobility are detected in cells of murine neuroblastoma C 1300. One of them is identified (proceeding from data of successive chemical degradation) as N-acylphosphatidylethanolamine. It may be a precursor of physiologically active N-acylethanolamines. N-palmitoyl and N-stearoylethanolamines are shown to inhibit the transport of ions through the veratrine-activated fast sodium channels as well as remove the effect of lysophospholipids accumulation in cells under the effect of veratrine.
Gulaia
N M
NM
Vas'kovskiĭ
V E
VE
Vysotskiĭ
M V
MV
Volkov
G L
GL
Govseeva
N N
NN
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004983:Ethanolamines / Q000032:analysis*; D006868:Hydrolysis; D051379:Mice; D009447:Neuroblastoma / Q000032:analysis*; D010714:Phosphatidylethanolamines / Q000032:analysis*; D014407:Tumor Cells, Cultured
D004983:Ethanolamines; C022203:N-acylethanolamines; D010714:Phosphatidylethanolamines
Obnaruzhenie N-atsilétanolaminovykh fosfolipidov v kletkakh neĭroblastomy C1300.