The significant of complement and immunoglobulin determination in healthy pregnant women and patients with EPH gestoses.
Complements C3 and C4, IgG, IgM, IgA and properdin factor B (PFB) were determined in maternal blood sera, sera from the umbilical cord and amniotic fluid in the group consisting of 30 healthy pregnant women and 30 patients with EPH gestoses. PFB and IgG were measured in urine, as well. Significant decrease of C3 complement in maternal sera and PFB in urine was found in the group with EPH gestoses, while a slight C4 complement enhancement was recorded in both maternal sera and the blood sera from the umbilical cord. PFB was conspicuously increased in maternal blood sera. IgG level was higher in the blood sera from the umbilical cord in comparison with that found in maternal sera in both groups examined. IgG, IgM and IgA levels were decreased in the group of patients with EPH gestoses in all fluids examined, while IgA level was significantly increased in the sera prepared from the blood from the umbilical cord.
Rosić
B
B
Clinic of Gynecology and Obstetrics, School of Medicine University of Belgrade, Yugoslavia.
Sulović
V
V
Juznić
N
N
Lazarević
B
B
Vidanović
M
M
D000653:Amniotic Fluid / Q000276:immunology; D003176:Complement C3 / Q000032:analysis*; D003181:Complement C4 / Q000032:analysis*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008431:Maternal-Fetal Exchange; D011225:Pre-Eclampsia / Q000276:immunology*; D011247:Pregnancy
D003176:Complement C3; D003181:Complement C4; D007136:Immunoglobulins