Carbohydrate histochemistry of human Brunner's glands.
Brunner's glands are known to produce neutral mucins. In order to achieve a better knowledge of their carbohydrate profile, we used five peroxidase-labeled lectins on surgical specimens of human duodenum. This method allowed us to identify at least two different types of neutral mucins in Brunner's glands secretion, thus demonstrating a heterogeneous mucin production. The structure of terminal oligosaccharidic chains in these glycoproteins has also been hypothesized.
Crescenzi
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I Cattedra di Anatomia ed Istologia Patologica, Dipartimento di Biopatologia Umana, Università, La Sapienza, Roma, Italy.
Barsotti
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P
Anemona
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Marinozzi
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V
D002011:Brunner Glands / Q000166:cytology / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D002240:Carbohydrate Sequence; D004386:Duodenum / Q000378:metabolism*; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D006801:Humans; D037102:Lectins; D008969:Molecular Sequence Data; D009093:Mucus / Q000378:metabolism
D037102:Lectins; D006735:Horseradish Peroxidase