title: Isolation of a human laminin B2 (LAMB2) cDNA clone and assignment of the gene to chromosome region 1q25----q31.
abstract: Laminin B2 is one of the three polypeptide chains of laminin, a large, complex glycoprotein synthesized by a variety of cells and specifically deposited in basement membranes. A cloned cDNA that encodes the human laminin B2 chain was isolated and characterized. The human laminin B2 gene (LAMB2) was assigned to region 1q25----q31 by (1) hybridization of the probe to DNA from a panel of human x mouse somatic cell hybrids containing different human chromosomes and (2) in situ hybridization to isolated metaphase chromosomes.
authors.affiliation: Department of Human Genetics, Roswell Park Memorial Institute, New York State Department of Health, NY 14263.
authors.forename: Y
authors.initials: Y
authors.lastname: Fukushima
authors.forename: T
authors.initials: T
authors.lastname: Pikkarainen
authors.forename: T
authors.initials: T
authors.lastname: Kallunki
authors.forename: R L
authors.initials: RL
authors.lastname: Eddy
authors.forename: M G
authors.initials: MG
authors.lastname: Byers
authors.forename: L L
authors.initials: LL
authors.lastname: Haley
authors.forename: W M
authors.initials: WM
authors.lastname: Henry
authors.forename: K
authors.initials: K
authors.lastname: Tryggvason
authors.forename: T B
authors.initials: TB
authors.lastname: Shows
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002878:Chromosomes, Human, Pair 1; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D006801:Humans; D007797:Laminin / Q000235:genetics*; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012689:Sequence Homology, Nucleic Acid
chemical_list: D007797:Laminin; D004247:DNA