title: A study of ionic conductances involved in plateau potential activity in putative vasopressinergic neurons in primary cell culture.
abstract: Vasopressin neurons in hypothalamic cell culture display regenerative calcium-dependent plateau potentials. The present study was undertaken to investigate the mechanisms underlying their time course and periodicity. Intracellular recordings showed that the duration of the plateaux was controlled by a progressive activation of a voltage- and calcium-dependent potassium conductance, but not by a progressive inactivation of calcium conductances. The refractory period appeared to be due to a calcium-dependent potassium conductance activated by membrane potential depolarization.
authors.affiliation: I.N.S.E.R.M. U.176, Université de Bordeaux II, France.
authors.forename: P
authors.initials: P
authors.lastname: Legendre
authors.forename: D A
authors.initials: DA
authors.lastname: Poulain
authors.forename: J D
authors.initials: JD
authors.lastname: Vincent
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D005333:Fetus / Q000166:cytology; D007031:Hypothalamus / Q000166:cytology / Q000502:physiology*; D008564:Membrane Potentials; D051379:Mice; D009431:Neural Conduction; D009474:Neurons / Q000502:physiology*; D011188:Potassium / Q000502:physiology*; D014667:Vasopressins / Q000502:physiology*
chemical_list: D014667:Vasopressins; D011188:Potassium