The possible role of substances inhibiting protein synthesis on the treatment of the spongiform encephalopathies.
The transmissible spongiform encephalopathies are probably caused by infectious proteinaceous agents called prions. It is suggested that these encephalopathies may be amenable to treatment by substances which inhibit protein synthesis.
Schwarz
K O
KO
Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153.
D000818:Animals; D002493:Central Nervous System Diseases / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D006801:Humans; D008954:Models, Biological; D011328:Prions / Q000187:drug effects; D011500:Protein Synthesis Inhibitors / Q000627:therapeutic use*; D012897:Slow Virus Diseases / Q000188:drug therapy*
D011328:Prions; D011500:Protein Synthesis Inhibitors