title: An analysis of esterase activities from surgeonfish tissues yields evidence of an atypical pseudocholinesterase.
abstract: 1. Esterases from tissues of the surgeonfish (Teleostei, Perciformes, Acanthuridae) are characterized electrophoretically and include several carboxylesterases, an acetylesterase, and an atypical pseudocholinesterase (pseudo-ChE). 2. The pseudo-ChE occurs in several isozymic forms including sialated and asialated slightly-anodal forms found principally in liver, and a larger, asialated asymmetric form that barely penetrates the 10% PAGE gel matrix found together with true AChE in epaxial muscle, brain, and eye. 3. Characterization of these three pseudo-ChE activities suggest that they are decidedly atypical in the intermediacy of their substrate and inhibitor specificities relative to classically-defined AChE and pseudo-ChE activities.
authors.forename: W S
authors.initials: WS
authors.lastname: Leibel
mesh_terms: D000818:Animals; D002091:Butyrylcholinesterase / Q000302:isolation & purification / Q000378:metabolism*; D002802:Cholinesterases / Q000378:metabolism*; D006031:Glycosylation; D007526:Isoelectric Point; D008970:Molecular Weight; D010473:Perciformes / Q000378:metabolism*; D013379:Substrate Specificity; D014018:Tissue Distribution
chemical_list: D002091:Butyrylcholinesterase; D002802:Cholinesterases