title: Specific antibody containing cells in the porcine respiratory tract following intraperitoneal and intratracheal immunisation.
abstract: Pigs were immunised intraperitoneally with ovalbumin in Freund's complete adjuvant and subsequently challenged intratracheally with ovalbumin. The results show that the group receiving two intratracheal challenges had a significantly greater antiovalbumin-containing cell response in the lamina propria of the respiratory tract. With intraperitoneal immunisation or intratracheal challenge alone the response was negligible. The immunoglobulin isotype of the anti-ovalbumin containing cells was predominantly IgG. There was also a substantial antibody containing cell response in the lung which was also IgG. These findings are discussed in relation to immunity within the porcine respiratory tract.
authors.affiliation: New South Wales Agriculture and Fisheries, Veterinary Laboratories, Glenfield, Australia.
authors.forename: R F
authors.initials: RF
authors.lastname: Sheldrake
authors.forename: L F
authors.initials: LF
authors.lastname: Romalis
authors.forename: M
authors.initials: M
authors.lastname: Saunders
mesh_terms: D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology*; D007114:Immunization / Q000662:veterinary*; D007070:Immunoglobulin A / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D008168:Lung / Q000166:cytology / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology; D010047:Ovalbumin / Q000276:immunology; D010537:Peritoneum / Q000276:immunology; D013552:Swine / Q000276:immunology*; D014132:Trachea / Q000166:cytology / Q000276:immunology*
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D010047:Ovalbumin