Leucine absorption after jejunoileal bypass in rats.
Jejunal and ileal absorption of L-leucine has been studied in rats subjected to jejunoileal bypass and in sham-operated rats, for five minute periods, using a perfusion technique. Aminoacid concentrations were: 1, 2.5, 5, 10 and 25 mM. In some experiments methionine was added to determine simple diffusion. The ratio of the active/diffusive components of absorption were calculated at the different luminal aminoacid concentrations in both groups of rats, showing that this ratio was lower in control animals.
Carreras
O
O
Departamento de Fisiología Animal, Facultad de Farmacia, Sevilla, Spain.
Murillo
M L
ML
Delgado
M J
MJ
Bolufer
J
J
D000818:Animals; D001693:Biological Transport, Active; D007082:Ileum / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D007581:Jejunoileal Bypass; D007583:Jejunum / Q000378:metabolism*; D007930:Leucine / Q000493:pharmacokinetics*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D007930:Leucine