Serum fructosamine does reflect levels of glycated serum albumin in insulin-dependent diabetics.
Fructosamine was measured in the serum of 62 patients with insulin-dependent diabetes (IDD) and 32 non-diabetics and the results compared with glycated albumin levels (GSA) measured using the affinity medium Cibarcron blue F3GA. Good correlations were found both for the IDD patients (r = 0.93) and the combined group of IDD plus non-diabetics (r = 0.95). We conclude, that fructosamine measurements accurately reflect GSA concentrations, and, therefore, provide a practical method for assessing intermediate term glycaemia in IDD.
Lloyd
D R
DR
Department of Chemical Pathology, Royal Albert Edward Infirmary, Wigan, UK.
Marples
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D002846:Chromatography, Affinity / Q000379:methods; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005260:Female; D019270:Fructosamine; D006595:Hexosamines / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012709:Serum Albumin / Q000032:analysis*; D014227:Triazines
D006595:Hexosamines; D012709:Serum Albumin; D014227:Triazines; C025616:glucosylated serum albumin; D019270:Fructosamine; C012842:Cibacron Blue F 3GA