title: [The acute hemorheologic effect of calcium dobesilate].
abstract: In a series 40 subjects without manifest vascular disorders received 1000 mg Calcium dobesilate (Doxium). Before and 3 hours after application the viscoelasticity of whole blood as well as plasma viscosity and the hematocrit were determined. The statistical analysis was performed by Wilcoxon-test. The viscosity of whole blood and the hematocrit decreased with a significance of p less than or equal to 0.001, whereas the elasticity decreased in a significance manner of p less than or equal to 0.01. Plasma viscosity remained uncharged. The results show an effect of hemodilution, which could be very important for treatment of hyperviscosity.
authors.affiliation: Krankenhaus der Barmherzigen Brüder, Graz-Eggenberg.
authors.forename: P
authors.initials: P
authors.lastname: Költringer
authors.forename: O
authors.initials: O
authors.lastname: Eber
authors.forename: G
authors.initials: G
authors.lastname: Klima
authors.forename: W
authors.initials: W
authors.lastname: Langsteger
authors.forename: P
authors.initials: P
authors.lastname: Wakonig
authors.forename: P
authors.initials: P
authors.lastname: Lind
authors.forename: W
authors.initials: W
authors.lastname: Rothlauer
mesh_terms: D000328:Adult; D001557:Benzenesulfonates / Q000494:pharmacology*; D001809:Blood Viscosity / Q000187:drug effects*; D002123:Calcium Dobesilate / Q000494:pharmacology*; D005260:Female; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D012212:Rheology
chemical_list: D001557:Benzenesulfonates; D002123:Calcium Dobesilate
vernacular_title: Der hämorheologische Akuteffekt von Kalziumdobesilat.