title: Effect of iodine deficiency on craniofacial growth in young common marmosets (Callithrix jacchus).
abstract: The effects of iodine deficiency on general and craniofacial growth were determined in young common marmosets. Examinations, including direct measurement, cephalometric radiology, and dental examination, were performed at three-month intervals from birth to 1 year on a cross-sectional sample of three groups of marmosets. The groups were those on a normal diet, n = 50; an iodine-deficient diet during gestation and for 1 year postnatally, n = 26; and an iodine-deficient diet only during gestation (returned to a normal diet at 1 month after birth), n = 18. The iodine-deficient animals were smaller in all dimensions, compared with controls, but they did not have typical cretin facies. Animals that were iodine deficient during gestation but subsequently fed a normal diet were small initially but displayed compensatory growth, so that by 1 year they were nearly normal in size.
authors.affiliation: Department of Dentistry, University of Adelaide, South Australia.
authors.forename: A N
authors.initials: AN
authors.lastname: Goss
authors.forename: W J
authors.initials: WJ
authors.lastname: Sampson
authors.forename: G C
authors.initials: GC
authors.lastname: Townsend
authors.forename: G H
authors.initials: GH
authors.lastname: McIntosh
mesh_terms: D000367:Age Factors; D000818:Animals; D002144:Callithrix; D005147:Facial Bones / Q000254:growth & development* / Q000473:pathology; D005260:Female; D007455:Iodine / Q000172:deficiency*; D011247:Pregnancy; D012886:Skull / Q000254:growth & development* / Q000473:pathology
chemical_list: D007455:Iodine