title: Sequence-defined dimer block synthesis from unprotected nucleoside.
abstract: mediates to synthesize the oligodeoxynucleotides have been synthesize otected nucleoside using morpholinophosphorditetrazolide. From these sequence-defined oligodeoxynucleotides were also synthesized. The gen is composed of following steps; a) reaction of 5'-O-protected nucleo orpholinophosphorditetrazolide (phosphitilation), b) reaction of the nucleoside phosphoramidite with the second nucleoside (condensation), ueous oxidation with t-BuOOH (oxidation). RE 1/hlp F2/cmt F3/ext F4/can F5/nxt F6/ins F7/up F8/dwn F9/fin
authors.affiliation: Division of Molecular Engineering, Graduate School of Engineering, Kyoto University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Shimidzu
authors.forename: H
authors.initials: H
authors.lastname: Ozaki
authors.forename: S
authors.initials: S
authors.lastname: Yamoto
authors.forename: S
authors.initials: S
authors.lastname: Maikuma
authors.forename: K
authors.initials: K
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Yamana
mesh_terms: D007202:Indicators and Reagents; D009705:Nucleosides; D009711:Nucleotides / Q000138:chemical synthesis*; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship
chemical_list: D007202:Indicators and Reagents; D009705:Nucleosides; D009711:Nucleotides; D009838:Oligodeoxyribonucleotides