High frequency of autonomic as well as peripheral neuropathy in patients with malnutrition-related diabetes mellitus.
We assessed peripheral and autonomic nerve function in 27 diabetics. Ten had malnutrition-related diabetes mellitus (MRDM), eight insulin-dependent diabetes mellitus (IDDM), and nine non-insulin-dependent diabetes mellitus (NIDDM). The frequency of peripheral neuropathy was 70, 78 and 13% in MRDM, NIDDM and IDDM respectively. Furthermore, the frequency of abnormality in cardiac beat-to-beat variation was 50 and 38% in MRDM and IDDM respectively, whereas our NIDDM patients did not show this abnormality. The patients with MRDM thus revealed a high frequency of not only peripheral but also autonomic neuropathy. Autonomic dysfunction appears to be a new characteristic of MRDM, not mentioned by the WHO study group.
Sutjahjo
A
A
Department of Medicine, Airlangga University - Dr. Sutomo Hospital, Surabaya, Indonesia.
Taniguchi
H
H
Hendromartono
Tjokroprawiro
A
A
Baba
S
S
D001341:Autonomic Nervous System / Q000503:physiopathology; D003920:Diabetes Mellitus / Q000209:etiology*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D009748:Nutrition Disorders / Q000150:complications*; D010525:Peripheral Nerves / Q000503:physiopathology