A comparison of two ulcerogenic techniques.
Long Evans rats 45, 130, or 280 days old were exposed either to a supine restraint or a water restraint treatment for two hr. This was followed by a 2-hr rest period. Core body temperature was recorded every 30 min. Stress-induced hypothermia was greatest in the water restraint treatment and in younger rats irrespective in both restraint conditions. The water restraint procedure as compared to the supine restraint produced significantly more ulcers in 130- and 280-day-old rats.
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Veterans Administration Medical Center, Perry Point, MD 21902.
D000818:Animals; D001833:Body Temperature Regulation; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical / Q000523:psychology; D013276:Stomach Ulcer / Q000523:psychology*; D013315:Stress, Psychological / Q000150:complications*