LKE red cell antigen and its relationship to P1 and Pk: serological study of a large family.
The fourth example of human anti-LKE was identified in the serum of an antenatal patient. Study of the red cells of the proband and her family confirmed the recessive inheritance of the LKE- phenotype. The blood groups of the family confirmed that Pk expression is greater on cells from LKE- members than on those from LKE+ members. In this family, the expression of LKE varied with the P1 phenotype. LKE- individuals occurred with an incidence of 0.0017 in the donor population of the Glasgow and West of Scotland Region.
Bruce
M
M
Glasgow and West of Scotland Blood Transfusion Service, Law Hospital, Carluke, UK.
Watt
A
A
Gabra
G S
GS
Mitchell
R
R
Lakhesar
D
D
Tippett
P
P
D001789:Blood Group Antigens / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007519:Isoantigens / Q000276:immunology*; D010127:P Blood-Group System / Q000235:genetics / Q000276:immunology*; D010375:Pedigree; D010641:Phenotype; D011247:Pregnancy
D001789:Blood Group Antigens; D007519:Isoantigens; D010127:P Blood-Group System