A comparison of nerve regeneration across a sural nerve graft and a vascularized pseudosheath.
Nerve regeneration across a vascularized pseudosheath and a sural nerve graft was compared in a primate model using histologic and electrophysiologic parameters for regeneration. At 12 months, regeneration was noted across both the vascularized pseudosheath and the sural nerve graft. Although histologic and electrophysiologic properties of the regenerated nerve were significantly different from the normal ulnar nerve, the quality of regeneration noted between experimental groups was similar.
Mackinnon
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Division of Plastic Surgery and Neurosurgery, University of Toronto, Ont., Canada.
Dellon
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D000818:Animals; D004594:Electrophysiology; D008252:Macaca fascicularis; D008297:Male; D008959:Models, Neurological; D009416:Nerve Regeneration; D013127:Spinal Nerves / Q000502:physiology*; D013497:Sural Nerve / Q000033:anatomy & histology / Q000502:physiology* / Q000637:transplantation; D014459:Ulnar Nerve / Q000033:anatomy & histology / Q000601:surgery*