Influences of dopaminergic systems on the blink reflex.
The effect of the anti-dopaminergic drug haloperidol (6 mg/day i.m. for 2 days) on the blink reflex elicited by electric stimulation of supraorbital nerves was investigated in 12 adult volunteers. A significant increase in amplitude of the early component (R1) of the reflex was observed. This increase disappeared within 5 days of stopping the drug. Possible neural systems which might be involved in these effects are considered.
Raffaele
R
R
Clinica Neurologica, Università di Catania.
Emery
P
P
Palmeri
A
A
Ricca
G
G
Perciavalle
V
V
D000328:Adult; D001767:Blinking / Q000187:drug effects*; D004558:Electric Stimulation; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009770:Obsessive Behavior / Q000188:drug therapy
D006220:Haloperidol