title: Transport of L-cystine in human umbilical vein endothelial cells in culture.
abstract: The uptake of L-cystine into cultured human umbilical vein endothelial cells has been shown to occur by a Na+-independent system which is inhibited by L-glutamate and L-homocysteine, but not by other amino acids. It is likely that the system transporting L-cystine is shared by L-glutamate. Thiol groups associated with membrane bound components appear to be essential for L-cystine uptake but it is not yet evident whether these constitute an integral part of the transporter per se.
authors.affiliation: Department of Biochemistry, University College, Cardiff, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Ewadh
authors.forename: N
authors.initials: N
authors.lastname: Tudball
authors.forename: F A
authors.initials: FA
authors.lastname: Rose
mesh_terms: D001692:Biological Transport; D002478:Cells, Cultured; D003553:Cystine / Q000378:metabolism*; D004727:Endothelium / Q000378:metabolism*; D006801:Humans; D014471:Umbilical Veins / Q000378:metabolism
chemical_list: D003553:Cystine