title: [Operability of primary inoperable pelvic tumors by preoperative regional hyperthermia in combination with systemic chemotherapy exemplified by Ewing's sarcoma].
abstract: Failure of local tumor control is of critical importance in the clinical management of large pelvic tumors. For bulky sarcomas of the pelvis a new treatment strategy could be of importance in the future using preoperative regional hyperthermia combined with systemic chemotherapy. In our case history of a patient with unresectable Ewing sarcoma of the pelvis no tumor response could be observed during multi-drug chemotherapy alone. However, after treatment with regional hyperthermia combined with systemic chemotherapy, the tumor mass became resectable and was separated from the adjacent tissue by a fibrotic pseudocapsule. Histological evaluation of the tumor tissue showed a complete change of the pattern.
authors.affiliation: Orthopädische Klinik, Klinikum Grosshadern.
authors.forename: P
authors.initials: P
authors.lastname: Böhm
authors.forename: C J
authors.initials: CJ
authors.lastname: Wirth
authors.forename: R
authors.initials: R
authors.lastname: Issels
authors.forename: H
authors.initials: H
authors.lastname: Riess
authors.forename: W
authors.initials: W
authors.lastname: Dressler
authors.forename: J M
authors.initials: JM
authors.lastname: Gokel
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006428:Hemipelvectomy; D006801:Humans; D006979:Hyperthermia, Induced; D008297:Male; D010384:Pelvic Bones / Q000601:surgery*; D010386:Pelvic Neoplasms / Q000188:drug therapy / Q000601:surgery*; D012512:Sarcoma, Ewing / Q000188:drug therapy / Q000601:surgery*
vernacular_title: Operabilität primär inoperabler Beckentumoren durch präoperative regionale Hyperthermie in Kombination mit systemischer Chemotherapie am Beispiel eines Ewing-Sarkoms.