title: Regional alterations in long bone produced by internal fixation devices. Part I. 85Sr clearance.
abstract: We examined the effect of rigid plate application on the radiostrontium clearance of the intact canine femur at 6 months. We examined each of the component surgical steps. We calculated the clearance both for the whole bone and for each of the five transverse sections of the whole bone. Screw application, but not drilling, increased the clearance in the segment about the screw holes. Plate application produced an increase in the segment beneath the plate as well as around the screws and in the whole bone. These changes are accomplished not only by an absolute increase in clearance to the middle three segments, but by a relative diminution in clearance by the most proximal and distal segments. The histomorphometric changes in long bones following rigid plating may be accompanied by regional increases in bone blood flow.
authors.affiliation: Department of Surgery, University of Texas Medical Branch, Galveston 77550.
authors.forename: W J
authors.initials: WJ
authors.lastname: Daum
authors.forename: D J
authors.initials: DJ
authors.lastname: Simmons
authors.forename: J H
authors.initials: JH
authors.lastname: Calhoun
authors.forename: A R
authors.initials: AR
authors.lastname: Benedetto
mesh_terms: D000818:Animals; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging; D001860:Bone Plates; D001863:Bone Screws; D001842:Bone and Bones / Q000098:blood supply*; D004285:Dogs; D005269:Femur / Q000098:blood supply; D005593:Fracture Fixation, Internal / Q000295:instrumentation*; D007511:Ischemia / Q000000981:diagnostic imaging*; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D013326:Strontium Radioisotopes
chemical_list: D013326:Strontium Radioisotopes