Lithium intoxication with acute renal failure and death.
A 65-year-old female presented with only gastrointestinal symptoms eight to ten hours after an acute ingestion of an unknown amount of lithium carbonate. The serum lithium concentration was 8.5 mEq/L. Forty-eight hours postingestion she developed acute renal failure, deteriorating mental status, and cardiovascular collapse. Despite both hemodialysis and peritoneal dialysis the patient died approximately four and one-half days after ingestion. A direct nephrotoxic effect of lithium is proposed.
Rose
S R
SR
Clinical Toxicology Services, University Hospital, Jacksonville, FL 32209.
Klein-Schwartz
W
W
Oderda
G M
GM
Gorman
R L
RL
Young
W W
WW
D058186:Acute Kidney Injury / Q000097:blood / Q000139:chemically induced* / Q000503:physiopathology; D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008094:Lithium / Q000097:blood / Q000506:poisoning*
D008094:Lithium; D003404:Creatinine