title: External quality control in the determination of neonatal bilirubin. An approach to the improvement of results.
abstract: The reliability of bilirubin analyses is especially important in cases of neonatal hyperbilirubinaemia. However, when the means of the results of external quality control surveys and the method-dependent stated values for control sera were compared with reference method values, differences of up to 10% were found. Further inaccuracy arose from interlaboratory imprecision, which showed coefficients of variation of at least 7%, and from greater or lesser interference from contamination of samples with haemoglobin. The present work investigates whether the current situation can be improved by available means.
authors.affiliation: Institut für Klinische Biochemie, Universität Bonn.
authors.forename: G
authors.initials: G
authors.lastname: Röhle
authors.forename: H
authors.initials: H
authors.lastname: Schlebusch
authors.forename: W J
authors.initials: WJ
authors.lastname: Geilenkeuser
authors.forename: R
authors.initials: R
authors.lastname: Kruse
mesh_terms: D001663:Bilirubin / Q000097:blood*; D019411:Clinical Laboratory Techniques / Q000592:standards; D006801:Humans; D007202:Indicators and Reagents; D007231:Infant, Newborn / Q000097:blood*; D011786:Quality Control; D013053:Spectrophotometry / Q000379:methods
chemical_list: D007202:Indicators and Reagents; D001663:Bilirubin