title: [Holoprosencephaly, polydactyly, cardiopathy: new syndrome or a new case of hydrolethalus?].
abstract: We present a foetus, 46,XY, with holoprosencephaly, hydrocephaly, unilateral lower limb post axial polydactyly, clubhands, auricular septal defect, umbilical cord hernia. The differential diagnosis of the condition is discussed: especially the hydrolethalus syndrome, and the Young and Madders' syndrome reported in 1987.
authors.affiliation: Service de Génétique, Hôtel-Dieu, Lyon.
authors.forename: S A
authors.initials: SA
authors.lastname: André
authors.forename: M P
authors.initials: MP
authors.lastname: Cordier
authors.forename: A M
authors.initials: AM
authors.lastname: Beaufrère
authors.forename: M
authors.initials: M
authors.lastname: Guillaud
authors.forename: J M
authors.initials: JM
authors.lastname: Robert
mesh_terms: D000015:Abnormalities, Multiple / Q000473:pathology*; D005385:Fingers / Q000002:abnormalities; D006330:Heart Defects, Congenital / Q000473:pathology; D006801:Humans; D006849:Hydrocephalus / Q000473:pathology; D013577:Syndrome
vernacular_title: Holoprosencéphalie, polydactylie, cardiopathie: nouveau syndrome ou un nouveau cas d'hydrolethalus?