title: A model reaction for the repair of nucleic acids. The repair of thymidine bromohydrins.
abstract: Bromohydrins, which were damaged products of thymidines (2, 3, and 4), were repaired with sunlight of heat via a radical mechanism to regenerate the thymidines. A hypothesis for the biological significance of thymidine in DNA is presented.
authors.affiliation: Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Harayama
authors.forename: R
authors.initials: R
authors.lastname: Yanada
authors.forename: T
authors.initials: T
authors.lastname: Akiyama
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Fujita
authors.forename: F
authors.initials: F
authors.lastname: Yoneda
mesh_terms: D004249:DNA Damage; D004260:DNA Repair; D006358:Hot Temperature; D008957:Models, Genetic; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D013472:Sunlight; D013936:Thymidine / Q000031:analogs & derivatives*
chemical_list: C054175:thymidine bromohydrin; D013936:Thymidine