title: Response rates to a staged antibiotic regimen in febrile neutropenic patients.
abstract: In a prospective study of 50 patients with prolonged neutropenia, we observed a 75% response rate to a staged empirical antibiotic regimen used to treat 101 episodes of fever. Additions or modifications to the protocol were rarely necessary. The use of an approach such as this improves the management of febrile neutropenic patients.
authors.affiliation: Department of Medical Microbiology, Charing Cross, London, UK.
authors.forename: R A
authors.initials: RA
authors.lastname: Barnes
authors.forename: T R
authors.initials: TR
authors.lastname: Rogers
mesh_terms: D000293:Adolescent; D000328:Adult; D000380:Agranulocytosis / Q000150:complications*; D000900:Anti-Bacterial Agents; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005335:Fever of Unknown Origin / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D009503:Neutropenia / Q000150:complications*
chemical_list: D000900:Anti-Bacterial Agents