title: [Frequency of structural chromosome aberrations in the hepatocytes of rats exposed to polymeric 239Pu].
abstract: Intravenous injection of polymeric 239Pu(IV) nitrate (166.5, 55.5 and 18.5 kBq/kg body mass) to Wistar rats was shown to produce biphase changes in the frequency of hepatocyte chromosome aberrations. The increase in the structural damages to chromosomes at later times of observation was a pronounced function of radiation dose. The absence of such a dependence at early times was evidently due to the elimination of damaged liver parenchyma cells.
authors.forename: M L
authors.initials: ML
authors.lastname: Zakharova
authors.forename: T I
authors.initials: TI
authors.lastname: Uriadnitskaia
authors.forename: A L
authors.initials: AL
authors.lastname: Sokhranich
authors.forename: V S
authors.initials: VS
authors.lastname: Revina
authors.forename: A P
authors.initials: AP
authors.lastname: Nifatov
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations; D007275:Injections, Intravenous; D008099:Liver / Q000528:radiation effects* / Q000648:ultrastructure; D008297:Male; D009566:Nitrates; D011005:Plutonium / Q000008:administration & dosage; D011108:Polymers; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D009566:Nitrates; D011108:Polymers; C015459:plutonium nitrate; D011005:Plutonium
vernacular_title: Chastota strukturnykh povrezhdeniĭ khromosom gepatitsitov krys pri deĭstvii polimernogo 239Pu.