Dendritic invagination of developing optic tract axons in the hamster.
Between E15 and P4 in the hamster, axons of retinal ganglion cells in the optic tract over the dorsal lateral geniculate nucleus, are invaginated by, and make synaptic contacts with, small processes interpreted as tips or appendages of geniculate dendrites. In some cases a branch-like protrusion emerges from the axon at or close to the invagination. We hypothesize that the invaginations may be part of the mechanism by which retinocollicular axons are induced to branch and establish the retinogeniculate pathway.
Bhide
P G
PG
Department of Anatomy and Developmental Biology, University College London, U.K.
Lieberman
A R
AR
Campbell
G
G
D000818:Animals; D001369:Axons / Q000502:physiology* / Q000648:ultrastructure; D006224:Cricetinae / Q000254:growth & development*; D003712:Dendrites / Q000502:physiology* / Q000648:ultrastructure; D005314:Embryonic and Fetal Development; D005829:Geniculate Bodies / Q000254:growth & development* / Q000648:ultrastructure; D008647:Mesocricetus / Q000254:growth & development* / Q000502:physiology; D008854:Microscopy, Electron; D012160:Retina / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000502:physiology* / Q000648:ultrastructure