title: Hypomanic behaviour associated with familial spastic paraplegia.
abstract: Psychiatric manifestations of familial spastic paraplegia are rare and have been described only infrequently. A 35-year-old male is reported, who presented both hypomanic behaviour and gait disturbances as features of a previously undiagnosed familial spastic paraplegia. This association implies that the CNS manifestations of familial spastic paraplegia may overlap with the neurochemical or neuroanatomic substrata regulating mood.
authors.affiliation: Institute of Neurology, St. Radboud Hospital, Catholic University, Nijmegen, The Netherlands.
authors.forename: P H
authors.initials: PH
authors.lastname: Jansen
authors.forename: A
authors.initials: A
authors.lastname: Keyser
authors.forename: B C
authors.initials: BC
authors.lastname: Raes
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000235:genetics* / Q000523:psychology; D003937:Diagnosis, Differential; D015417:Hereditary Sensory and Motor Neuropathy / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree; D015419:Spastic Paraplegia, Hereditary / Q000235:genetics* / Q000523:psychology