Rapid 31P NMR test of liver function.
The 31P NMR spectrum of perfused rat liver was found to be dependent on the exogenous carbon available to the tissue. When pyruvate was supplied to liver initially perfused with lactate, Pi decreased, phosphoenol pyruvate and phosphomonoesters increased, and nucleotide pools remained the same. It is proposed that these changes can be used to evaluate liver function.
Thoma
W J
WJ
Department of Biochemistry, University of Minnesota, Navarre 55392.
Uğurbil
K
K
D000818:Animals; D066298:In Vitro Techniques; D008111:Liver Function Tests / Q000295:instrumentation / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D051381:Rats