title: Diameters and segment relations during the cardiac cycle in the canine left ventricle.
abstract: The relations between left ventricular antero-posterior, septum-free wall diameters and an anterior subendocardial segment were studied by sonomicrometry in seven open-chest anesthetized dogs, during the control state and during left ventricular and right ventricular pressure overload for low and high left ventricular filling pressures. A linear relationship between antero-posterior and septal-free wall shortening was observed during control and during left ventricular pressure overload when left ventricular filling pressure was high. For low end-diastolic ventricular pressure, there was the same relationship during ejection with an isovolumic lengthening of the septal-free wall diameter. This relationship was shifted downwards during pulmonary artery stenosis for both high and low left ventricular filling pressure, which produced a significant decrease in end-diastolic septum-free wall diameter without significant modifications of end-diastolic antero-posterior diameter. The anterior segment exhibited behavior similar to that of the calculated left ventricular circumference. Subendocardial anterior segment measurements in the open-chest dog model can be used as indices of left ventricular circumference.
authors.affiliation: I.N.S.E.R.M. U2, Hôpital Léon Bernard, Limeil-Brévannes, France.
authors.forename: L
authors.initials: L
authors.lastname: Hittinger
authors.forename: B
authors.initials: B
authors.lastname: Crozatier
mesh_terms: D000818:Animals; D004285:Dogs; D006321:Heart / Q000033:anatomy & histology / Q000502:physiology* / Q000503:physiopathology; D006352:Heart Ventricles / Q000033:anatomy & histology / Q000503:physiopathology; D013318:Stroke Volume; D016276:Ventricular Function