[Activation of electron transport at the terminal site of the respiratory chain by the submitochondrial fluid from the rat and guinea pig liver].
Supermitochondrial liquid (SL) of rat and guinea-pig liver increases the activity of 2, 3, 5 triphenyltetrasolium chloride (TPC) and tetrasolium violet (TV) reduction at succinate, NADH and NADPH oxidation by mitochondria (MC). SL contains an activating factor A, being evidently of a protein nature and factor B, increasing the activating activity of factor A. NAD, NADP, NADH and NADP at 5 x 10(-5)-1 x 10(-4) M concentration activate the TPC and TV reduction at succinate oxidation by mitochondria. TPC and TV reduction at succinate and NADP oxidation by mitochondria makes antimicin and cyanide sensitive. SL does not influence succinate dehydrogenase activity, when used as electron acceptors of ferricyanide, blue Vurster, cytochrome C, blue and violet nitrotetrasolium. Activation of electron transfer chair between cytochrome C and oxygen is supposed to be responsible for such an effect.
Shmuter
G M
GM
D000818:Animals; D001921:Brain / Q000378:metabolism; D004579:Electron Transport; D005110:Extracellular Space / Q000378:metabolism; D005260:Female; D006168:Guinea Pigs; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology / Q000378:metabolism*; D009928:Organ Specificity; D010084:Oxidation-Reduction; D051381:Rats; D013045:Species Specificity; D013385:Succinate Dehydrogenase / Q000378:metabolism; D013778:Tetrazolium Salts / Q000378:metabolism
D013778:Tetrazolium Salts; C009591:triphenyltetrazolium; D013385:Succinate Dehydrogenase
Aktivatsiia peredachi élektronov na terminal'nom uchastke dykhatel'noĭ tsepi nadmitokhondrial'noĭ zhidkost'iu pecheni krysy i morskoĭ svinki.