title: Elastase production in clinical isolates of Aspergillus.
abstract: Clinical isolates of Aspergillus species were tested, both retrospectively and prospectively, for elastase activity using rose bengal-elastin agar plates. Patient records were then reviewed to determine the clinical diagnosis including the presence or absence of aspergillosis. All isolates that caused invasive aspergillosis produced elastase, but not all isolates producing elastase were associated with invasive disease.
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, Ohio.
authors.forename: J C
authors.initials: JC
authors.lastname: Rhodes
authors.forename: R B
authors.initials: RB
authors.lastname: Bode
authors.forename: C M
authors.initials: CM
authors.lastname: McCuan-Kirsch
mesh_terms: D001228:Aspergillosis / Q000201:enzymology / Q000382:microbiology; D001230:Aspergillus / Q000201:enzymology* / Q000302:isolation & purification; D006801:Humans; D010196:Pancreatic Elastase / Q000096:biosynthesis* / Q000378:metabolism
chemical_list: D010196:Pancreatic Elastase