Systemic lupus erythematosus with complement deficiency and IgA anti-cardiolipin antibody.
A case of aggressive systemic lupus erythematosus with a fatal outcome is described. The patient had a complement component deficiency with a strong family history of autoimmune disease. An exceptional feature of the case was the detection of a high titre of anti-cardiolipin antibody of the IgA class only.
Markey
A C
AC
Department of Dermatology, Guy's Hospital, London, U.K.
MacDonald
D M
DM
D001323:Autoantibodies / Q000032:analysis*; D002308:Cardiolipins / Q000276:immunology*; D003165:Complement System Proteins / Q000172:deficiency*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology*; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008875:Middle Aged
D001323:Autoantibodies; D002308:Cardiolipins; D007070:Immunoglobulin A; D003165:Complement System Proteins