The activation of pyruvate dehydrogenase by glucagon in hepatocytes is diminished by phorbol myristate acetate: a role for cytoplasmic calcium in dehydrogenase regulation.
Staddon
J M
JM
National Institute on Aging, Gerontology Research Center, Baltimore, MD 21224.
Hansford
R G
RG
D000818:Animals; D002118:Calcium / Q000502:physiology*; D002478:Cells, Cultured; D003600:Cytosol / Q000378:metabolism; D004789:Enzyme Activation; D005934:Glucagon / Q000494:pharmacology*; D006706:Homeostasis; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism*; D051381:Rats; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*
D011768:Pyruvate Dehydrogenase Complex; D005934:Glucagon; D013755:Tetradecanoylphorbol Acetate; D002118:Calcium