Quiescent fibroblasts in a cellular model system.
Quiescent fibroblasts are non-dividing cells in a reversible postmitotic state induced by lowering the serum concentration of the medium (e.g. from 10% to 0.3%). Three to seven days after lowering the serum concentration only minor metabolic changes will take place in the cells. During this period the quiescent fibroblasts can be used experimentally in a model system for various periods of time.
Kristensen
S R
SR
Department of Clinical Chemistry, Odense University Hospital, Denmark.
Petersen
P H
PH
D000255:Adenosine Triphosphate / Q000032:analysis*; D002460:Cell Line; D003470:Culture Media; D004247:DNA / Q000032:analysis*; D005347:Fibroblasts / Q000032:analysis* / Q000166:cytology; D006801:Humans; D008938:Mitosis; D011506:Proteins / Q000032:analysis*
D003470:Culture Media; D011506:Proteins; D000255:Adenosine Triphosphate; D004247:DNA