Intracranial hypertension causing visual failure in cryptococcus meningitis.
Thirty four patients with cryptococcal meningitis seen in the University of Malaya medical centre since 1980 were reviewed. Eleven patients had bilateral papilloedema and visual impairment but eventually survived. Seven patients had intensive aggressive measures, including shunting to reduce intracranial hypertension irrespective of ventricular size shown in CT scan, and showed substantial improvement in vision. It is concluded that papilloedema and visual failure in cryptococcal meningitis reflects raised intracranial pressure and that this should be treated vigorously.
Tan
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Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
D000293:Adolescent; D000328:Adult; D002648:Child; D003453:Cryptococcosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008581:Meningitis / Q000503:physiopathology*; D008875:Middle Aged; D009900:Optic Nerve / Q000503:physiopathology; D010211:Papilledema / Q000503:physiopathology*; D011559:Pseudotumor Cerebri / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000503:physiopathology*; D014792:Visual Acuity