Diagnosis of peripheral pulmonary emboli by MR imaging: an experimental study in dogs.
The peripheral pulmonary arteries of 5 dogs were embolized with boiled autologous clots via the external right jugular vein. Angiography determined the location and approximate size of the emboli in the peripheral pulmonary arteries. With spin echo techniques, transverse axial magnetic resonance (MR) images (0.3 T, 12.77 MHz) were obtained in each animal from apex to thorax base, on a permanent magnet scanner. The sensitivity of MR imaging was assessed to detect these clots and to determine their size and location. In 2 dogs, scans were also obtained before embolization in order to exclude possible artifactual areas of increased signal. Fourteen out of 19 emboli were identified on the MR scans as areas of increased signal. Their diameter measured a minimum of 2.7 mm matching the filling defects seen on the angiograms. There were three false positive emboli on MR probably related to slow blood flow in the inferior vena cava. There were 9 false negative emboli on MR. The increased MR signal seen in dogs with pulmonary emboli results from the embolus itself and from slow blood flow distal to the obstructive embolus.
Ovenfors
C O
CO
Department of Radiological Sciences, University of California, School of Medicine, Los Angeles 90024.
Batra
P
P
D000818:Animals; D004285:Dogs; D008279:Magnetic Resonance Imaging; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000473:pathology; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography