[Success of a parlodel test in the differential diagnosis of syndromes of disturbed prolactin secretion].
Altogether 33 women with various forms of the syndrome of hyperprolactinemia (hypophyseal adenoma, idiopathic disorders of prolactin secretion--PL, and normoprolactinemic galactorrhea) and 6 controls were investigated. An acute parlodel test at a dose of 5 mg with subsequent determination of the blood levels of PL and TSH was performed in 2 and 4 h after drug administration. The most noticeable disorders in the dopaminergic regulation of pituitary activity were observed in pituitary adenomas which were characterized by a dramatically disturbed response of PL and TSH to parlodel. In hyperprolactinemia of nontumorous genesis PL and and TSH secretion in tests was also changed. The parlodel test seems to be a valuable method for differential diagnosis of the syndrome of disturbed PL secretion.
Gerasimov
G A
GA
Balabolkin
M I
MI
D000236:Adenoma / Q000150:complications; D001971:Bromocriptine; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000150:complications; D011237:Predictive Value of Tests; D011388:Prolactin / Q000378:metabolism*; D013972:Thyrotropin / Q000097:blood
D001971:Bromocriptine; D011388:Prolactin; D013972:Thyrotropin
Rezul'tativnost' proby s parlodelom v differentsial'noĭ diagnostike sindromov narushennoĭ sekretsii prolaktina.