title: A comparison of GAD- and GABA-immunoreactive neurons in the first somatosensory area (SI) of the rat cortex.
abstract: Neurons immunoreactive for anti-glutamic acid decarboxylase (anti-GAD) and anti-gamma-aminobutyric acid (anti-GABA) were compared in adjacent sections from the rat somatosensory cortex (SI). GAD- and GABA-positive neurons in animals either treated or not treated with colchicine were found to occur at a ratio of 1:2. Measurement of areas of GAD- and GABA-immunoreactive neurons confirmed the presence of an 'exuberant' GABA-positive neuronal population not visualized by the GAD antiserum.
authors.affiliation: Department of Neurophysiology, Istituto Neurologico C. Besta, Milan, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Spreafico
authors.forename: S
authors.initials: S
authors.lastname: De Biasi
authors.forename: C
authors.initials: C
authors.lastname: Frassoni
authors.forename: G
authors.initials: G
authors.lastname: Battaglia
mesh_terms: D000818:Animals; D002452:Cell Count; D005968:Glutamate Decarboxylase / Q000378:metabolism*; D007150:Immunohistochemistry; D051381:Rats; D013003:Somatosensory Cortex / Q000166:cytology / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase