Quantification of visible light-induced melanogenesis in human skin.
Exposure of normal skin to visible light (400-700 nm) resulted in the induction of immediate pigment darkening (IPD), immediate erythema and a persistent (delayed) tanning reaction. The intensity of pigmentation and time course of the reaction were monitored by measuring chromaticity coordinates. Both IPD and immediate erythema faded over a 24-h period but, unlike erythema, the pigmentation did not totally disappear and the residual tanning response remained unchanged for the rest of the 10-day observation period. The threshold dose for IPD with visible light was between 40 and 80 J/cm2, while the threshold dose for "persistent" pigmentation was greater than or equal to 80 J/cm2.
Porges
S B
SB
Simon Greenberg Foundation, Skin Study Center, KGL, Philadelphia, Pennsylvania.
Kaidbey
K H
KH
Grove
G L
GL
D000293:Adolescent; D000328:Adult; D003116:Color; D004890:Erythema / Q000209:etiology; D005260:Female; D006801:Humans; D008027:Light; D008297:Male; D008543:Melanins / Q000528:radiation effects; D012867:Skin / Q000528:radiation effects*; D012880:Skin Pigmentation / Q000528:radiation effects*
D008543:Melanins