Late onset isofenphos neurotoxicity.
Late progressive polyneuropathy followed by pyramidal findings in a 20 year old agricultural labourer who ingested Isofenphos solution during his work, is presented. The patient was confined to a wheelchair within 6 weeks, regained walking ability within 6 months, and a 23 months' follow up revealed slight additional clinical improvement with minimal progression of the pyramidal signs. The neuropathic clinical manifestations, the EMG and the nerve conduction studies were compatible with a pathology of a distal, mainly axonal, mainly motor neuropathy.
Catz
A
A
Loewenstein Rehabilitation Center, Raanana, Israel.
Chen
B
B
Jutrin
I
I
Mendelson
L
L
D000328:Adult; D004576:Electromyography; D005500:Follow-Up Studies; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D009046:Motor Neurons / Q000187:drug effects*; D009468:Neuromuscular Diseases / Q000139:chemically induced*; D009784:Occupational Diseases / Q000139:chemically induced*; D009946:Organothiophosphorus Compounds / Q000506:poisoning*; D010243:Paralysis / Q000139:chemically induced
D007306:Insecticides; D009946:Organothiophosphorus Compounds; C035019:isofenphos