Annular elastolytic giant cell granuloma.
We treated a 13-year-old girl who had annular erythematous lesions with central atrophic areas, which had been present on her trunk and limbs for 4 months. Histological examination revealed patchy dermal lymphohistocytic infiltration with multinucleated giant cells which were phagocytosing elastic fibers, causing them to disappear. The active border of the lesions regressed after intradermal injection of corticosteroids. The classification of the disease and its differential diagnosis from the usual granuloma annulare, inflammatory anetoderma, O'Brien's actinic granuloma, and Convit's disease are discussed.
Boneschi
V
V
Second Department of Dermatology, University of Milan, Italy.
Brambilla
L
L
Fossati
S
S
Parini
F
F
Alessi
E
E
D000293:Adolescent; D001706:Biopsy; D003937:Diagnosis, Differential; D004547:Elastic Tissue / Q000473:pathology*; D005260:Female; D006101:Granuloma, Giant Cell / Q000145:classification / Q000473:pathology*; D006801:Humans; D010587:Phagocytosis; D012871:Skin Diseases / Q000145:classification / Q000473:pathology*