title: Concentration of steroid sex hormones in the plasma of hens in relation to oviduct tumours.
abstract: 1. The concentrations of 17 beta-oestradiol (E2) and progesterone (P) were determined in the plasma of layer breeder hens at the end of their first laying season, in relation to neoplasms of the oviduct, including magnum tumours and leiomyomas. 2. The plasma concentration of E2 was higher in tumorous than in non-tumorous hens indicating it may be involved in the development of oviduct tumours. 3. The plasma concentrations of P in tumorous and non-tumorous hens were not significantly different, suggesting no active role of P in the aetiology of the tumours. 4. The E2: P ratio was higher in tumorous than in non-tumorous hens. This ratio could be of value in predicting hens at risk of developing oviduct tumours.
authors.affiliation: AFRC Institute for Animal Health, Houghton Laboratory, Huntingdon, Cambridgeshire, England.
authors.forename: A D
authors.initials: AD
authors.lastname: Anjum
authors.forename: L N
authors.initials: LN
authors.lastname: Payne
mesh_terms: D000230:Adenocarcinoma / Q000097:blood / Q000662:veterinary*; D000236:Adenoma / Q000097:blood / Q000662:veterinary*; D000818:Animals; D002645:Chickens / Q000097:blood*; D004958:Estradiol / Q000097:blood*; D005260:Female; D005833:Genital Neoplasms, Female / Q000097:blood / Q000662:veterinary*; D007889:Leiomyoma / Q000097:blood / Q000662:veterinary*; D010057:Oviducts; D011201:Poultry Diseases / Q000097:blood*; D011374:Progesterone / Q000097:blood*
chemical_list: D011374:Progesterone; D004958:Estradiol