Cross-reaction pattern of the cationic emulsifier oleamidopropyl dimethylamine.
13 patients allergic to the cationic emulsifier oleamidopropyl dimethylamine were tested with a series of related amide-amine type surfactants in order to investigate its cross-reaction pattern. With 1 exception, all patients reacted to at least 4 of the test materials. Most reactions were observed to ricinoleamidopropyl dimethylamine lactate and tallowamidopropyl dimethylamine (11 patients, 85%); 9 patients (of 12 tested, 75%) reacted to lauramidopropyl dimethylamine and 6 (46%) to myristamidopropyl dimethylamine. A certain pattern of cross-reactivity was recognised.
de Groot
A C
AC
Department of Dermatology, Carolus & Willem-Alexander Hospital, Hertogenbosch, The Netherlands.
Jagtman
B A
BA
van der Meeren
H L
HL
Bruynzeel
D P
DP
Bos
J D
JD
den Hengst
C W
CW
Weyland
J W
JW
D000293:Adolescent; D000328:Adult; D002412:Cations; D003358:Cosmetics / Q000009:adverse effects; D003429:Cross Reactions; D003877:Dermatitis, Contact / Q000209:etiology / Q000276:immunology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011437:Propylamines / Q000009:adverse effects / Q000276:immunology*; D013501:Surface-Active Agents / Q000009:adverse effects
D002412:Cations; D003358:Cosmetics; D011437:Propylamines; D013501:Surface-Active Agents; C044477:N-(3-(dimethylamino)propyl)oleamide