[Effect of bone marrow cells on colony-forming stromal cells in guinea pigs and on the proliferation of their cultured descendents].
In the presence of irradiated bone marrow cells the efficiency of stromal colony formation increases from 0.8 +/- 0.2 to 3.6 +/- 0.4 per 10(4) explanted bone marrow cells. The growth-stimulating activity of bone marrow cells on passaged bone marrow fibroblasts depends on growth conditions of passages to which irradiated bone marrow cells are added. The response of proliferating bone marrow fibroblasts to stimulating activity of bone marrow cells is low, while addition of bone marrow cells to fibroblast cultures stimulates their proliferation.
Zorina
A I
AI
Gorskaia
Iu F
IuF
Grosheva
A G
AG
Fridenshteĭn
A Ia
AIa
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects; D001854:Bone Marrow Cells; D002455:Cell Division / Q000528:radiation effects; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D005347:Fibroblasts / Q000166:cytology / Q000528:radiation effects; D006168:Guinea Pigs; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000528:radiation effects
Vliianie kostnomozgovykh kletok na koloneobrazuiushchie stromal'nye kletki morskikh svinok i proliferatsiiu ikh kul'tural'nykh potomkov.