title: [Neonatal vitamin K prophylaxis and vitamin k deficiency hemorrhages in Switzerland 1986-1988].
abstract: On the basis of an inquiry held in Switzerland in May 1988, over 99% of all newborn receive vitamin K prophylaxis, 59% orally and 41% intramuscularly. In the previous 2 1/2 years, ten cases of bleeding due to vitamin K deficiency had been observed, of which two were inadequately documented. In two children there was early haemorrhage and late haemorrhage in eight. The latter were all exclusively breast-fed and had received oral vitamin K prophylaxis. Seven presented with vitamin K deficiency due to cholestasis or chronic diarrhea. The only "idiopathic" case is insufficiently documented. The advantages and disadvantages of oral and intramuscular prophylaxis are discussed. A definite stand in favour of the one route or the other is not possible at present. However, the continuation of general prophylaxis is undoubtedly necessary.
authors.affiliation: Pädiatrische Klinik, Kinderspital Luzern.
authors.forename: O
authors.initials: O
authors.lastname: Tönz
authors.forename: G
authors.initials: G
authors.lastname: Schubiger
mesh_terms: D005260:Female; D006470:Hemorrhage / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013557:Switzerland; D014812:Vitamin K / Q000008:administration & dosage / Q000627:therapeutic use*; D014813:Vitamin K Deficiency / Q000150:complications*; D006475:Vitamin K Deficiency Bleeding / Q000517:prevention & control
chemical_list: D014812:Vitamin K
vernacular_title: Neonatale Vitamin-K-Prophylaxe und Vitamin-K-Mangelblutungen in der Schweiz 1986-1988.