title: Biomaterials for facial bone augmentation: comparative studies.
abstract: Presently no material is available which is entirely satisfactory for facial bone augmentation. These studies examine several of those already in clinical use, made from various polymers in solid, porous, and woven forms. Homograft bone has also been studied, as an implant material. All materials were used in situations for which they are currently recommended clinically. Bioglass (Bioglass is a trademark of the University of Florida) implants, which are suggested for clinical use, have been studied in the same model and results show that their surface activity provides a more satisfactory immobilization, both in the short and long term, than does the tissue ingrowth on which most of the other materials depend. Results show that in this model as well as in clinical practice, porous and woven materials provoke in tissues a continuing cellular response which will always compromise long-term clinical success. Autograft bone has associated morbidity and is unpredictable with respect to its incorporation into host tissue and persistence at the site. Bioglass, however, was immobilized successfully at both hard and soft tissue interfaces without the need for porosity, could be satisfactorily shaped in the operating room, and, in addition, had the bonelike hardness which is not provided by any other available material.
authors.affiliation: J. Hillis Miller Health Center, University of Florida, Gainesville 32610.
authors.forename: J
authors.initials: J
authors.lastname: Wilson
authors.forename: G E
authors.initials: GE
authors.lastname: Merwin
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects; D002516:Ceramics; D004285:Dogs; D004341:Drug Evaluation; D005147:Facial Bones / Q000601:surgery*; D006099:Granuloma / Q000473:pathology; D011108:Polymers; D019736:Prostheses and Implants / Q000009:adverse effects; D012826:Silicone Elastomers
chemical_list: D001672:Biocompatible Materials; C022107:Bioglass; D011108:Polymers; D012826:Silicone Elastomers