PUVA therapy and the lens reconsidered.
On the basis of animal experiments there appears to be a theoretical chance that lens changes will occur in patients receiving PUVA treatment. In the published studies the incidence of lens changes in patients treated with PUVA is very low. In this study changes were observed both during PUVA treatment and during a long follow-up period. The absence of typical lens changes in patients aged 55 years and older is remarkable. A possible relationship between these findings and information obtained by experiment is discussed.
Van Deenen
W L
WL
Department of Ophthalmology, Academic Hospital Maastricht, The Netherlands.
Lamers
W P
WP
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002386:Cataract / Q000175:diagnosis / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D011701:PUVA Therapy / Q000009:adverse effects*; D011565:Psoriasis / Q000188:drug therapy; D014820:Vitiligo / Q000188:drug therapy