Sialyltransferase activity in erythrocyte membranes and serum in patients with myotonic dystrophy.
Sialyltransferase activity was measured in erythrocyte membranes and in serum in patients with myotonic dystrophy and in matched healthy controls. The reason for assaying this enzyme was to study a possible mechanism behind a previously reported deficiency of glycoprotein-bound sialic acid in the erythrocyte membrane in patients with this disease. No significant differences in sialyltransferase activity with endogenous or different exogenous glycoprotein acceptors were found.
Stibler
H
H
Department of Neurology, Karolinska Hospital, Stockholm, Sweden.
Sydow
O
O
D000293:Adolescent; D000328:Adult; D004910:Erythrocyte Membrane / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000201:enzymology*; D012799:Sialyltransferases / Q000097:blood*; D000094802:beta-D-Galactoside alpha 2-6-Sialyltransferase
D012799:Sialyltransferases; D000094802:beta-D-Galactoside alpha 2-6-Sialyltransferase