The behaviour of specific antibody classes in human hydatid disease.
The behaviour of IgE antibodies was investigated by the micro-ELISA method (IgE-ELISA) in patients affected by hydatidosis or in patients who had already been operated on. The results were correlated with those obtained by IgG-ELISA, IgM-ELISA, IgA-ELISA and IHA tests. In the preoperative phase the IgG-ELISA method proved to be as sensitive (80%) as the IHA test (78.5%); the IgE-ELISA method showed a good sensitivity (72.8%) with a positive rate for the IgE-ELISA/IHA of 92.7%. The IgM- and IgA-ELISA methods were of moderate sensitivity. The IgE-ELISA proved to be much more suitable than the other methods for postoperative control, since the persistence of positivity 4 years after surgery suggests the involvement of a relapse.
Baldelli
F
F
Institute of Infectious Diseases, University of Perugia, Italy.
Tassi
C
C
Papili
R
R
Pauluzzi
S
S
D000906:Antibodies / Q000145:classification*; D000918:Antibody Specificity; D004443:Echinococcosis / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006386:Hemagglutination Tests / Q000379:methods; D006801:Humans; D007070:Immunoglobulin A / Q000276:immunology; D007073:Immunoglobulin E / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology; D007075:Immunoglobulin M / Q000276:immunology
D000906:Antibodies; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007073:Immunoglobulin E