title: Immunohistochemical studies of lymphadenosis benigna cutis occurring in a tattoo.
abstract: We report the development of a lymphoproliferative reaction in the red areas of a tattoo in a 53-year-old man. The results of histologic and immunohistochemical studies were consistent with a diagnosis of lymphadenosis benigna cutis. Patch tests showed a strong, delayed-type hypersensitivity to several mercury products. The pathogenetic mechanisms operative in the development of this reaction are discussed.
authors.affiliation: Department of Dermatology, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: J U
authors.initials: JU
authors.lastname: Rijlaarsdam
authors.forename: D P
authors.initials: DP
authors.lastname: Bruynzeel
authors.forename: W
authors.initials: W
authors.lastname: Vos
authors.forename: C J
authors.initials: CJ
authors.lastname: Meijer
authors.forename: R
authors.initials: R
authors.lastname: Willemze
mesh_terms: D003877:Dermatitis, Contact / Q000150:complications / Q000209:etiology; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008628:Mercury / Q000009:adverse effects; D008875:Middle Aged; D012878:Skin Neoplasms / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D013653:Tattooing / Q000009:adverse effects*
chemical_list: D008628:Mercury