title: [Particle induced X-ray emission for trace element analysis of hairs from patients with cancer].
abstract: In this paper, trace element analysis of the hairs from the patients with nasopharyngeal carcinoma (NPC) and osteoma was made using particle induced X-ray emission (PIXE) technique in order to obtain some information on the correlation between trace element and these two tumors. The hair samples of 34 NPC patients were each collected before and three months after radiotherapy (60Co) (group 1). The hair specimens from 34 osteoma patients were collected preoperatively and postoperatively. For comparison, 65 hair samples were collected from 40 normal subjects (group 2) and 25 NPC patients, who had received radiotherapy (60Co) five years before without any recrudescence (group 3). The trace element analysis of all specimens was made by PIXE. The results show that there is a significant difference between groups 1 and 2 (P less than 0.01) but no difference is found between groups 2 and 3 for Mn, Cu, Zn, As etc. content in the hairs. Cu and Zn content in the hairs of the osteoma patients is much lower than that of the normal subjects (P less than 0.01) while for K, Ti and Mn content, the former is higher than the latter. The above experimental results are discussed in detail.
authors.affiliation: Fudan University, Shanghai.
authors.forename: H Y
authors.initials: HY
authors.lastname: Yao
authors.forename: X Z
authors.initials: XZ
authors.lastname: Zeng
authors.forename: C R
authors.initials: CR
authors.lastname: Lu
authors.forename: X D
authors.initials: XD
authors.lastname: Wang
authors.forename: J M
authors.initials: JM
authors.lastname: Che
authors.forename: M Y
authors.initials: MY
authors.lastname: Mu
authors.forename: J
authors.initials: J
authors.lastname: Yang
authors.forename: Z X
authors.initials: ZX
authors.lastname: Wang
authors.forename: H S
authors.initials: HS
authors.lastname: Zhang
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Yie
mesh_terms: D006197:Hair / Q000032:analysis*; D006801:Humans; D009303:Nasopharyngeal Neoplasms / Q000032:analysis*; D010016:Osteoma / Q000032:analysis*; D013052:Spectrometry, X-Ray Emission; D014131:Trace Elements / Q000032:analysis*
chemical_list: D014131:Trace Elements