title: [The cholinergic system in the early development of chickens. 1. Choline acetyltransferase and acetylcholinesterase as the key regulators of acetylcholine metabolism].
abstract: Acetylcholine esterase (AChE, EC 3.1.1.7) and choline acetyltransferase (CAT, EC 2.3.1.6) activities were studied in the early chick embryos. Gastrulation is accompanied by a sharp increase in the AChE activity which was most pronounced in anterior hypoblast. Three molecular of AChE (4.7, 6.8 and 10.9 S) were identified in the extract of chick embryos using a sucrose density gradient centrifugation. The CAT activity remained unchanged during gastrulation but increased twice at the end of gastrulation.
authors.forename: T A
authors.initials: TA
authors.lastname: Laasberg
mesh_terms: D000109:Acetylcholine / Q000378:metabolism*; D000110:Acetylcholinesterase / Q000032:analysis / Q000378:metabolism*; D000818:Animals; D002499:Centrifugation, Density Gradient; D002642:Chick Embryo; D002795:Choline O-Acetyltransferase / Q000032:analysis / Q000378:metabolism*; D005775:Gastrula / Q000378:metabolism; D006651:Histocytochemistry; D009024:Morphogenesis; D011950:Receptors, Cholinergic / Q000378:metabolism*
chemical_list: D011950:Receptors, Cholinergic; D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase; D000109:Acetylcholine
vernacular_title: Kholinérgicheskaia sistema v rannem razvitii kur. 1. Kholinatsetiltransferaza i atsetilkholinésteraza kak kliuchevye reguliatory metabolizma atsetilkholina.