Physical exercise affects cholinesterases and organophosphate response.
1. Cholinesterase activities in blood and tissues of control and exercising rats with and without organophosphate (OP) exposure were studied. 2. Physical exercise increased total cholinesterase and butyrylcholinesterase activities in rats without OP exposure in blood and diaphragm. In brain physical exercise had no effect on acetylcholinesterase activity. 3. Physical exercise diminished cholinesterase inhibition in blood and tissues after OP exposure.
Ryhänen
R
R
Department of Physiology, University of Kuopio, Finland.
Kajovaara
M
M
Harri
M
M
Kaliste-Korhonen
E
E
Hänninen
O
O
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000201:enzymology; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D002802:Cholinesterases / Q000097:blood / Q000378:metabolism*; D003964:Diaphragm / Q000201:enzymology; D066298:In Vitro Techniques; D007531:Isoflurophate / Q000494:pharmacology; D008297:Male; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D010805:Physical Conditioning, Animal; D051381:Rats; D011916:Rats, Inbred F344; D012524:Sarin / Q000494:pharmacology
D002800:Cholinesterase Inhibitors; D009943:Organophosphorus Compounds; D007531:Isoflurophate; D012524:Sarin; D000110:Acetylcholinesterase; D002802:Cholinesterases