Synthesis and antifungal properties of 14-aminomethyl-substituted lanosterol derivatives.
Cooper
A B
AB
Schering Corporation, Bloomfield, New Jersey 07003.
Wright
J J
JJ
Ganguly
A K
AK
Desai
J
J
Loebenberg
D
D
Parmegiani
R
R
Feingold
D S
DS
D000818:Animals; D000935:Antifungal Agents / Q000138:chemical synthesis*; D065607:Cytochrome P-450 Enzyme Inhibitors; D004875:Ergosterol / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D005658:Fungi / Q000187:drug effects; D007810:Lanosterol / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000494:pharmacology; D008099:Liver / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D051381:Rats; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D065607:Cytochrome P-450 Enzyme Inhibitors; D007810:Lanosterol; D004875:Ergosterol