title: [Changes in the spleen structure during treatment of patients with generalized Hodgkin's disease].
abstract: Data obtained from 35 autopsies and morphological examination of the irradiated and non-irradiated spleen are analyzed. Morphological changes in the spleen as a result of radiation are described. Curability of Hodgkin's disease foci is established to be possible in the spleen irradiated with the dose of 35-40 Gy. A prophylactic spleen irradiation decreases the possibility of its metastatic damage in generalized Hodgkin's disease.
authors.forename: A V
authors.initials: AV
authors.lastname: Gubareva
authors.forename: A B
authors.initials: AB
authors.lastname: Markochev
authors.forename: L P
authors.initials: LP
authors.lastname: Simbirtseva
authors.forename: M A
authors.initials: MA
authors.lastname: Asaturian
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013154:Spleen / Q000473:pathology / Q000528:radiation effects*; D013160:Splenic Neoplasms / Q000473:pathology / Q000517:prevention & control
vernacular_title: Izmenenie struktury selezenki pri terapii bol'nykh generalizovannym limfogranulematozom.