Clinical evaluation of sulbactam + ampicillin in the treatment of pediatric urinary tract infections.
Twenty-five children (16 females and 9 males) aged from 8 months to 10 years with clinical and laboratory evidence of UTI were treated with sulbactam + ampicillin (SBT/AMP). Twenty-four of them were suffering from cystitis and one from pyelonephritis. Four of them were treated unsuccessfully prior to entry in the trial. The mean final dose of SBT/AMP was 47.69 mg/kg/die (ratio of SBT-AMP was 1:2). The patients were treated for 3 to 8 days (mean: 4.76 days). 84% were treated by i.m. route. No side effects or adverse experience were reported. Clinical cure was achieved in 25 patients (100%).
Solbiati
M
M
Institute of Infectious Diseases, University of Verona, Italy.
Danzi
M C
MC
D'Orazio
C
C
Bassetti
D
D
D000667:Ampicillin / Q000008:administration & dosage* / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013407:Sulbactam / Q000008:administration & dosage* / Q000009:adverse effects; D014552:Urinary Tract Infections / Q000188:drug therapy*
D000667:Ampicillin; D013407:Sulbactam