title: Polymorphism of debrisoquine hydroxylation among Finns and Lapps.
abstract: Debrisoquine hydroxylation polymorphism was studied in 155 Finns and 70 Lapps. The frequency of the poor metabolizer phenotype was 3.2% among Finns (95% confidence interval 0.4-6.0%) and 8.6% among Lapps (95% confidence interval 2.0-15.1%).
authors.affiliation: Department of Pharmacology, University of Oulu, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Arvela
authors.forename: M
authors.initials: M
authors.lastname: Kirjarinta
authors.forename: M
authors.initials: M
authors.lastname: Kirjarinta
authors.forename: N
authors.initials: N
authors.lastname: Kärki
authors.forename: O
authors.initials: O
authors.lastname: Pelkonen
mesh_terms: D003647:Debrisoquin / Q000378:metabolism* / Q000652:urine; D005387:Finland; D006801:Humans; D006900:Hydroxylation; D007546:Isoquinolines / Q000378:metabolism*; D010641:Phenotype; D011110:Polymorphism, Genetic; D012537:Scandinavian and Nordic Countries
chemical_list: D007546:Isoquinolines; D003647:Debrisoquin