title: Standardbred stallion gene transmission for twelve protein systems: evidence for selection in trotters.
abstract: The transmission ratios of alleles at 12 protein marker loci were computed individually for American Standardbred stallions in a genealogy of 5392 phenotyped horses. Over all loci there was significant gene transmission distortion for trotting stallions (p = 0.0019) but not for pacing stallions (p = 0.99). The transmission distortion was due to sire-specific effects (p = 0.0024) and not to increased transmission of one or the other allele of a given heterozygous genotype (p = 0.21). Individual-specific, non-random transmission of homologous chromosomes may provide a mechanism for selection to operate without requiring differential fitness for specific alleles or genotypes in the population as a whole.
authors.affiliation: Department of Psychiatry, University of Rochester Medical Center, New York 14642.
authors.forename: L R
authors.initials: LR
authors.lastname: Weitkamp
authors.forename: J W
authors.initials: JW
authors.lastname: MacCluer
authors.forename: S A
authors.initials: SA
authors.lastname: Guttormsen
authors.forename: R H
authors.initials: RH
authors.lastname: King
mesh_terms: D000818:Animals; D001769:Blood; D005684:Gait; D005819:Genetic Markers; D005838:Genotype; D006579:Heterozygote; D006736:Horses / Q000235:genetics*; D008297:Male; D010375:Pedigree; D012641:Selection, Genetic
chemical_list: D005819:Genetic Markers