[Changes in oxygen tension in tumor during induced hyperglycemia].
It is shown that tumour PO2 falls by the factor of 2 or 3 at the 120-150 min i/v glucose infusion (80 mg.kg-1.min-1) to the rats bearing Guerin carcinoma. This is due to a decrease oxygen transport into the tumour induced by inhibition of local blood flow.
Teplitskiĭ
M G
MG
Osinskiĭ
S P
SP
D000818:Animals; D001786:Blood Glucose / Q000502:physiology*; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D007262:Infusions, Intravenous; D009132:Muscles / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000098:blood supply / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure; D051381:Rats; D012039:Regional Blood Flow
D001786:Blood Glucose; D005947:Glucose; D010100:Oxygen
Izmenenie napriazheniia kisloroda v opukholi pri iskusstvennoĭ giperglikemii.