[Characteristics of the development of interphase death of hematopoietic tissue in dogs in response to gamma irradiation].
In experiments with 2-3 week dogs it was shown that whole-body gamma-irradiation with a dose of 3 Gy causes an insignificant absolute rise in the amount of degrading chromatin of the haemopoietic organs during the first 24 h following irradiation. After 48 h, this cell death parameter is normalized. A considerably lower radiosensitivity of lymphoid cells of dogs compared to small laboratory animals is indicated by a stable DNA content per 1 g of thymus, intactness of its structure after irradiation, and the absence of an increase in thymidine content of blood of young and adult dogs under the effect of 3-3.7 Gy radiation.
Ermolaeva
N V
NV
Afonin
A N
AN
Chirkova
L P
LP
Beletskaia
L V
LV
Beliaev
D L
DL
D000818:Animals; D002470:Cell Survival / Q000528:radiation effects; D004247:DNA / Q000032:analysis; D004285:Dogs; D005260:Female; D005720:Gamma Rays; D006413:Hematopoietic System / Q000528:radiation effects*; D007399:Interphase; D008297:Male; D013154:Spleen / Q000032:analysis; D013936:Thymidine / Q000097:blood; D013950:Thymus Gland / Q000032:analysis
D004247:DNA; D013936:Thymidine
Osobennosti proiavleniia interfaznoĭ gibeli krovetvornoĭ tkani u sobak v otvet na gamma-obluchenie.