Cytology in the diagnosis of pancreatic cancer.
The study of cytology in duodenal and/or pure pancreatic juice has been proposed in the differential diagnosis of pancreatic cancer. In our experience the sensitivity of cytology in duodenal juice, collected during Secretin-Cholecystokinin test, in diagnosing pancreatic cancer was 66.6%. False positive results were obtained only rarely (1.4%) in patients with chronic pancreatitis and benign diseases of the gastrointestinal tract. The cytological evaluation of pure pancreatic juice, obtained by ERCP, increases sensitivity up to 80-90%, especially when the combination of the results of ERCP and cytology is performed. Cytological examination of duodenal and/or pure pancreatic juice is a useful tool in detecting pancreatic malignancy and in differential diagnosis with chronic pancreatitis.
Del Favero
G
G
Istituto di Medicina Interna, Cattedra di Malattie dell'Apparato Digerente, Università degli Studi di Padova, Italy.
Fabris
C
C
Angonese
C
C
Basso
D
D
Rebuffi
A
A
Costantin
G
G
Matarazzo
R
R
Di Mario
F
F
Naccarato
R
R
D000208:Acute Disease; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004386:Duodenum / Q000473:pathology*; D006801:Humans; D007419:Intestinal Secretions / Q000378:metabolism*; D010189:Pancreatic Juice / Q000166:cytology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D010195:Pancreatitis / Q000175:diagnosis / Q000473:pathology