title: The occurrence of calcium salt deposition on dermal collagen fibres following electrical injury to porcine skin.
abstract: Deposition of calcium salts on collagen fibres has been shown to occur in cathode areas from 2 days to 2 months after exposure to direct current (d.c.) via contact knobs measuring 12 mm in diameter using energy level from 0.5 to 96 J and on day 7 after exposure to alternating current (a.c.) via pointed electrodes using energy level from 30 to 50 J. In order to determine the statistical relation of this histological observation to the type of energy applied 1095 biopsies from 49 pigs including biopsies from skin areas exposed to heat, 50 Hz a.c., 100 kHz a.c. and d.c. as well as from unexposed skin were examined. The specificity was 1.0 using calcium deposition as the test criterium. The sensitivity for cathode areas was found to vary from 0.52 to 1.0 depending on the biopsy technique and the number of days after exposure. Calcium salts on collagen fibres seem uniformly to be present in the cathode area from day 4 to 7, the positive test answer being depending on the biopsy technique. For 50 Hz a.c. the sensitivity using a pointed electrode was found to vary from 0.08 to 0.27 dependent on the number of days after exposure. For all other types of energy the sensitivity was 0.
authors.affiliation: Department of Dermato-venereology and Pathology, Bispebjerg Hospital, Copenhagen, Denmark.
authors.forename: T
authors.initials: T
authors.lastname: Karlsmark
authors.forename: O
authors.initials: O
authors.lastname: Aalund
authors.forename: L
authors.initials: L
authors.lastname: Danielsen
authors.forename: H K
authors.initials: HK
authors.lastname: Thomsen
authors.forename: O
authors.initials: O
authors.lastname: Nielsen
authors.forename: K G
authors.initials: KG
authors.lastname: Nielsen
authors.forename: I K
authors.initials: IK
authors.lastname: Genefke
mesh_terms: D000818:Animals; D002058:Burns, Electric / Q000378:metabolism / Q000473:pathology*; D002118:Calcium / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D012867:Skin / Q000378:metabolism / Q000473:pathology*; D013552:Swine
chemical_list: D003094:Collagen; D002118:Calcium