Lumbar myelography with iopamidol: a methodological approach to the investigation of side effects.
Pathophysiology of adverse reactions occurring during myelography with non-ionic contrast agents, such as iopamidol, seem related to their direct action on the nervous system. The authors try a multivariate approach, involving neurophysiological, neuropsychological and neurochemical parameters on a pilot group of twelve subjects. Any possible change in the above examinations is thoroughly analyzed and correlated to the postulated neurotoxic properties of contrast media.
Provinciali
L
L
Institute of Nervous System Diseases, University of Ancona, Italy.
Signorino
M
M
Giovagnoli
A R
AR
Baroni
M
M
Angeleri
F
F
Salvolini
U
U
Pasquini
U
U
Porta
M
M
Judice
A
A
Cerutti
R
R
D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology; D004569:Electroencephalography; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D006801:Humans; D007278:Injections, Spinal; D007479:Iopamidol / Q000008:administration & dosage / Q000009:adverse effects*; D009192:Myelography / Q000009:adverse effects*; D010865:Pilot Projects; D013223:Statistics as Topic; D014057:Tomography, X-Ray Computed
D007479:Iopamidol