title: Lithium intoxication with acute renal failure and death.
abstract: A 65-year-old female presented with only gastrointestinal symptoms eight to ten hours after an acute ingestion of an unknown amount of lithium carbonate. The serum lithium concentration was 8.5 mEq/L. Forty-eight hours postingestion she developed acute renal failure, deteriorating mental status, and cardiovascular collapse. Despite both hemodialysis and peritoneal dialysis the patient died approximately four and one-half days after ingestion. A direct nephrotoxic effect of lithium is proposed.
authors.affiliation: Clinical Toxicology Services, University Hospital, Jacksonville, FL 32209.
authors.forename: S R
authors.initials: SR
authors.lastname: Rose
authors.forename: W
authors.initials: W
authors.lastname: Klein-Schwartz
authors.forename: G M
authors.initials: GM
authors.lastname: Oderda
authors.forename: R L
authors.initials: RL
authors.lastname: Gorman
authors.forename: W W
authors.initials: WW
authors.lastname: Young
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000139:chemically induced* / Q000503:physiopathology; D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008094:Lithium / Q000097:blood / Q000506:poisoning*
chemical_list: D008094:Lithium; D003404:Creatinine