G6PD deficiency and breast cancer.
A study of the relative 2dG6P utilization in mononuclear cells from a group of 150 women with breast cancer was undertaken to evaluate a possible negative correlation between G6PD deficiency and cancer, as suggested by some authors. Twenty-one women (14.00%) were heterozygotes and 2 were homozygotes (1.33%). The prevalence found was not different from that expected. It would therefore seem that the G6PD Mediterranean allele does not play a protective role against the development of breast cancer.
Forteleoni
G
G
Clinica Pediatrica A. Filia, Università di Sassari, Italia.
Argiolas
L
L
Farris
A
A
Ferraris
A M
AM
Gaetani
G F
GF
Meloni
T
T
D000328:Adult; D000483:Alleles; D001943:Breast Neoplasms / Q000201:enzymology* / Q000209:etiology; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications*; D006801:Humans; D008875:Middle Aged
D005954:Glucosephosphate Dehydrogenase