Electrophysiologic studies on ventricular tachyarrhythmias in a chronic canine infarct model.
The development of a chronic canine infarct model has allowed us to (1) understand better the mechanisms of tachyarrhythmogenesis in infarction; (2) evaluate new antiarrhythmic regimens as well as other antitachycardia therapies, including cryoablation, laser ablation, pacing, and surgical techniques; (3) correlate directly the presence of low-level late potentials with myocardial activation in the presence of delayed and fractionated cardiac electrograms; and (5) evaluate critically our present methods of programmed electrical stimulation.
Moore
E N
EN
Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104.
Spear
J F
JF
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D002304:Cardiac Pacing, Artificial; D004285:Dogs; D004562:Electrocardiography; D009203:Myocardial Infarction / Q000150:complications*; D012815:Signal Processing, Computer-Assisted; D013610:Tachycardia / Q000175:diagnosis* / Q000209:etiology; D014693:Ventricular Fibrillation / Q000175:diagnosis* / Q000209:etiology
D000889:Anti-Arrhythmia Agents