Isolation of a human laminin B2 (LAMB2) cDNA clone and assignment of the gene to chromosome region 1q25----q31.
Laminin B2 is one of the three polypeptide chains of laminin, a large, complex glycoprotein synthesized by a variety of cells and specifically deposited in basement membranes. A cloned cDNA that encodes the human laminin B2 chain was isolated and characterized. The human laminin B2 gene (LAMB2) was assigned to region 1q25----q31 by (1) hybridization of the probe to DNA from a panel of human x mouse somatic cell hybrids containing different human chromosomes and (2) in situ hybridization to isolated metaphase chromosomes.
Fukushima
Y
Y
Department of Human Genetics, Roswell Park Memorial Institute, New York State Department of Health, NY 14263.
Pikkarainen
T
T
Kallunki
T
T
Eddy
R L
RL
Byers
M G
MG
Haley
L L
LL
Henry
W M
WM
Tryggvason
K
K
Shows
T B
TB
D000595:Amino Acid Sequence; D001483:Base Sequence; D002878:Chromosomes, Human, Pair 1; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D006801:Humans; D007797:Laminin / Q000235:genetics*; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012689:Sequence Homology, Nucleic Acid
D007797:Laminin; D004247:DNA