title: Robertsonian heterozygosity and male sterility.
abstract: Meiotic and synaptonemal complex studies using electron microscopy were carried out on infertile man with a 13/14 translocation. Synaptonemal complex analysis showed a typical trivalent with incomplete pairing of the acrocentric elements. The sterilizing effect caused by the failure of synapsis is discussed. This pairing failure has a diagnostic value and a poor prognosis.
authors.affiliation: Faculté de Médicine, Institute d'Embryology, Strasbourg/France.
authors.forename: O
authors.initials: O
authors.lastname: Gabriel-Robez
authors.forename: C
authors.initials: C
authors.lastname: Ratomponirina
authors.forename: C
authors.initials: C
authors.lastname: Cranz
authors.forename: A
authors.initials: A
authors.lastname: Weill
authors.forename: P A
authors.initials: PA
authors.lastname: Goldschmit
authors.forename: C
authors.initials: C
authors.lastname: Bollack
authors.forename: Y
authors.initials: Y
authors.lastname: Rumpler
mesh_terms: D000328:Adult; D002882:Chromosomes, Human, Pair 13; D002883:Chromosomes, Human, Pair 14; D006579:Heterozygote; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D008854:Microscopy, Electron; D008938:Mitosis; D011379:Prognosis; D014178:Translocation, Genetic