title: Quantification of visible light-induced melanogenesis in human skin.
abstract: Exposure of normal skin to visible light (400-700 nm) resulted in the induction of immediate pigment darkening (IPD), immediate erythema and a persistent (delayed) tanning reaction. The intensity of pigmentation and time course of the reaction were monitored by measuring chromaticity coordinates. Both IPD and immediate erythema faded over a 24-h period but, unlike erythema, the pigmentation did not totally disappear and the residual tanning response remained unchanged for the rest of the 10-day observation period. The threshold dose for IPD with visible light was between 40 and 80 J/cm2, while the threshold dose for "persistent" pigmentation was greater than or equal to 80 J/cm2.
authors.affiliation: Simon Greenberg Foundation, Skin Study Center, KGL, Philadelphia, Pennsylvania.
authors.forename: S B
authors.initials: SB
authors.lastname: Porges
authors.forename: K H
authors.initials: KH
authors.lastname: Kaidbey
authors.forename: G L
authors.initials: GL
authors.lastname: Grove
mesh_terms: D000293:Adolescent; D000328:Adult; D003116:Color; D004890:Erythema / Q000209:etiology; D005260:Female; D006801:Humans; D008027:Light; D008297:Male; D008543:Melanins / Q000528:radiation effects; D012867:Skin / Q000528:radiation effects*; D012880:Skin Pigmentation / Q000528:radiation effects*
chemical_list: D008543:Melanins