Thalassemia in the Silk Road region of China.
This paper summarizes data obtained during a screening program involving 11,563 persons from the Silk Road region in China. The mean incidence of thalassemia is 1.62% with an increase from east to west. The incidence in the Hui population (3.01%) is higher than in Kazaks (2.92%), and in Uygur (2.22%). The Han population also has a higher incidence (0.98%) than seen for other regions in Northern China. The thalassemias observed are classified into seven groups; beta-thalassemia accounts for 89.48% of the total, and alpha-thalassemia for 10.52%.
Qin
F
F
Laboratory of Medical Genetics, Western Region Hospital, Urumqi, P.R. China.
Li
H J
HJ
Li
L
L
Li
H W
HW
Zhang
X S
XS
Yi
J H
JH
Zhao
X N
XN
Zhang
C T
CT
Li
Z M
ZM
Xing
F L
FL
D002681:China; D008403:Mass Screening; D010375:Pedigree; D013789:Thalassemia / Q000453:epidemiology*