Premature labor contractions and the value of serum ferritin during pregnancy.
In general, the diagnosis of pregnancy-related anemia relies on the estimation of the hemoglobin level. The findings of this study suggest that the additional estimation of serum ferritin - a reliable index of the iron stores - can improve the diagnosis of anemia. Hematological data of 150 pregnant women were retrospectively related to the courses of pregnancy, in particular to the incidence of premature labor contractions. 70% of the pregnant women included in the investigation had a serum ferritin value below 20 micrograms/l and thus iron deficiency. If the hemoglobin value alone had been estimated, 50.6% of the women with iron deficiency (serum ferritin less than 20 micrograms/l) would not have been detected among those pregnant women with a hemoglobin value of more than 11 g/dl. These findings are also of particular relevance as a significant correlation has been found between the incidence of premature labor contractions and the serum ferritin level: only 11% of the pregnant women investigated whose serum ferritin values exceeded 20 micrograms/l had premature labor contractions, whereas premature labor was recorded in 48% of the pregnant women with serum ferritin values below 10 micrograms/l.
Goepel
E
E
Department of Gynecology, University Hospital, Hamburg-Eppendorf, FRG.
Ulmer
H U
HU
Neth
R D
RD
D000747:Anemia, Hypochromic / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D007752:Obstetric Labor, Premature / Q000097:blood* / Q000209:etiology; D011237:Predictive Value of Tests; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood* / Q000175:diagnosis; D011263:Pregnancy Trimester, Third; D012189:Retrospective Studies; D014590:Uterine Contraction
D005293:Ferritins