title: [The incidence of ventricular arrhythmia following direct current ablation, high-frequency current ablation and laser photo-ablation].
abstract: Incidence and severity of ventricular arrhythmias (VA) following transvenous catheter ablation have so far not been fully elucidated. In the present study we evaluated the comparative incidence of postablation ventricular arrhythmias following high voltage-direct current electrical ablation (DCA), radiofrequency-ablation (RFA), and laser-photoablation (LPA). Experiments were performed on a total of 26 anesthetized mongrel dogs (BW: 20-30 kg). DCA (n = 14; 150-200 J) and RFA (n = 7; 38.5-72.5 J) were performed unipolarly via a 6F USCI catheter, LPA (n = 5; 40-80 J) was delivered through a quarz core fiber (diameter 0.4 mm) housed within a special designed catheter. Energies were delivered to various sites of free wall and apical endocardium of the left ventricle. Immediately after DCA fast runs of ventricular tachycardia (VT) developed in 13 out of 14 dogs degenerating into ventricular fibrillation in two animals. Mean cycle length of induced VT was 298 +/- 86 ms. Persistent VA, morphologically mainly characterized by an accelerated idioventricular rhythm interrupted by runs of ventricular salvoes, occurred in 12 animals (mean rate: 78 +/- 13 VPB/min 3 h after ablation). During VT early endocardial activations were recorded from the ablation site. No significant correlation between total applied energy (150-550 J) and incidence of arrhythmogenic effects was observed. RFA and LPA induced ventricular salvoes and runs of non-sustained ventricular tachycardia, in one animal ventricular fibrillation occurred during RFA; however, no persistent arrhythmic activity developed after RFA and LPA, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Abt. Innere Medizin C, Westfälischen Wilhelms-Universität Münster.
authors.forename: G
authors.initials: G
authors.lastname: Hindricks
authors.forename: W
authors.initials: W
authors.lastname: Haverkamp
authors.forename: U
authors.initials: U
authors.lastname: Dute
authors.forename: H
authors.initials: H
authors.lastname: Gülker
mesh_terms: D000818:Animals; D004285:Dogs; D004562:Electrocardiography; D004564:Electrocoagulation / Q000379:methods*; D006352:Heart Ventricles / Q000473:pathology / Q000601:surgery*; D006439:Hemodynamics; D053685:Laser Therapy / Q000379:methods*; D013610:Tachycardia / Q000473:pathology / Q000601:surgery*
vernacular_title: Inzidenz ventrikulärer Arrhythmien nach Gleichstromablation, Hochfrequenzstromablation und Laser-Photoablation.