[Treatment of Wilson's disease with Zincteral].
In 27 patients with reliably diagnosed Wilson's disease treated previously with penicillamine (Cuprenil, Polfa) for from 10 months to 12 years penicillamine was withdrawn due to various adverse effects and replaced with zinc sulphate (Polish preparation Zincteral) in doses of 200 mg 4 times daily for 12 months. The neurological status was improved in 6 cases. No adverse effects of zinc sulphate were observed.
Kuczyńska-Zardzewiały
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Kliniki Chorób Naczyniowych Układu Nerwowego Instytutu Psychiatrii i Neurologii w Warszawie.
Rodo
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Członkowska
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D000328:Adult; D002570:Ceruloplasmin / Q000378:metabolism; D003300:Copper / Q000378:metabolism; D005260:Female; D006527:Hepatolenticular Degeneration / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D013431:Sulfates / Q000493:pharmacokinetics / Q000627:therapeutic use*; D015032:Zinc / Q000378:metabolism / Q000493:pharmacokinetics / Q000627:therapeutic use*; D019287:Zinc Sulfate
D013431:Sulfates; D019287:Zinc Sulfate; D003300:Copper; D002570:Ceruloplasmin; D015032:Zinc
Leczenie choroby Wilsona Zincteralem.