[Use of functional indices of the erythron system in the diagnosis of alcoholism].
A study was made of indices of the erythron system in 137 alcoholic patients (stages I, II, III). At all 3 stages a rise of the level of intraerythrocytic 2,3-DPG in erythrocytes and a serum erythropoietic titer was detected, at II and III stages--reticulocytosis and erythrocytic life reduction, and at III stage--a decrease in the number of erythrocytes. The results indicated the involvement of the erythron system in the compensation of changes developing in alcoholism, first of all hypoxia. A possibility of the use of 2,3-DPG determination for the diagnosis of alcoholism and antihypoxic drugs in combined therapy of alcoholism was discussed.
Vikulin
S V
SV
Popova
N L
NL
Pavlov
A D
AD
Morshakova
E F
EF
Afonina
S I
SI
D019794:2,3-Diphosphoglycerate; D000328:Adult; D000437:Alcoholism / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D004163:Diphosphoglyceric Acids / Q000097:blood; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000502:physiology*; D006801:Humans; D000860:Hypoxia / Q000097:blood; D008875:Middle Aged; D011086:Polycythemia / Q000097:blood
D004163:Diphosphoglyceric Acids; D019794:2,3-Diphosphoglycerate
Ispol'zovanie funktsional'nykh pokazateleĭ sistemy éritrona v diagnostike alkogolizma.