title: Idiopathic extrahepatic biliary atresia: recurrence in sibs in two families.
abstract: Since 1855, 11 instances of familial extrahepatic biliary atresia (EHBA) have been described. Genetic, environmental, vascular, and infectious causes for this disorder have been proposed. We report on 2 families each with 2 sibs with EHBA. We suggest that a genetic susceptibility to an environmental insult to the biliary tree may be responsible for the genesis of this disease.
authors.affiliation: University of Vermont College of Medicine, Burlington.
authors.forename: M L
authors.initials: ML
authors.lastname: Cunningham
authors.forename: V P
authors.initials: VP
authors.lastname: Sybert
mesh_terms: D001656:Biliary Atresia / Q000235:genetics* / Q000601:surgery; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn