A case of progressive subcortical gliosis presenting clinically as Steele-Richardson-Olszewski syndrome.
A patient presenting with the characteristic clinical features of Steele-Richardson-Olszewski syndrome is described, in whom neuropathological examination revealed atypical features, including extensive cortical and subcortical gliosis. The clinical and pathological features are discussed with particular reference to Creutzfeldt-Jacob disease and it is proposed that the case should be classified as progressive subcortical gliosis.
Will
R G
RG
Maida Vale Hospital for Nervous Diseases, London, UK.
Lees
A J
AJ
Gibb
W
W
Barnard
R O
RO
D001253:Astrocytes / Q000473:pathology; D001921:Brain / Q000473:pathology*; D002540:Cerebral Cortex / Q000473:pathology; D005260:Female; D005911:Gliosis / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D013494:Supranuclear Palsy, Progressive / Q000473:pathology*