title: [A rare case of cerebral aspergillus aneurysm at the site of temporary clip application].
abstract: Anterior communicating artery aneurysm was shown in a 48-year-old man who had suffered from subarachnoid hemorrhage (SAH) by cerebral angiography. Right pterional approach was performed on the 40th day after SAH. Premature ruptured occurred during aneurysmal manipulation and temporary clip (Scoville clip) was placed at the middle of the right A1 segment for fifteen minutes. the anterior communicating artery aneurysm was successfully clipped and postoperative course was uneventful. But, four days after the operation, the patient fell into coma following generalized tonic convulsion. Lumbar puncture showed fresh SAH. Consciousness recovered gradually to a lethargic state. A newly formed berry aneurysm was revealed on the righ A1 segment at the site of the temporary clip application by cerebral angiography performed on the seventh day after aneurysmal surgery. Second attack occurred on the 12th postoperative day and the patient died on the 16th day after the operation. Postmortem findings disclosed massive subarachnoid and intraventricular hemorrhage from the ruptured aneurysm at the right A1 segment. Microscopic examination of the aneurysm and the right A1 segment. microscopic examination of the aneurysm and the right A1 segment showed the extensive destruction of the artery and massive proliferation of aspergillus in the arterial wall which was prominent of its outer layer. The mechanism of the formation of the new aneurysm in this case was considered as follows: the arterial wall was primarily damaged by the temporary clip and was weakened rapidly by the invasion of aspergillus, probably producing thrombosis of the vast vasorum, hemorrhage, and necrosis in it.
authors.affiliation: Department of Neurological Surgery, Okayama University Medical School.
authors.forename: S
authors.initials: S
authors.lastname: Asari
authors.forename: A
authors.initials: A
authors.lastname: Nishimoto
authors.forename: M
authors.initials: M
authors.lastname: Murakami
mesh_terms: D000785:Aneurysm, Infected / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D001228:Aspergillosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000293:injuries*; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000473:pathology; D013345:Subarachnoid Hemorrhage / Q000209:etiology