A new approach to neocyte transfusion: preliminary report.
A method has been developed using phthalate oils to quality control units of young red cells (neocytes). Neocytes prepared by the NEOCEL system have a mean young red cell enrichment of 90% with only 3.4% less than 80%. Neocytes prepared in a blood cell processor have an average enrichment of 81% with 27% less than 75%. Based on a 12 month period, the patients as a group have received an average of 14% fewer transfusions and an 18% decrease in red cells per kg/yr as compared to frozen red cells.
Kevy
S V
SV
Department of Medicine, Children's Hospital, Boston, Massachusetts 02115.
Jacobson
M S
MS
Fosburg
M
M
Renaud
M
M
Scanlon
A
A
Carmen
R
R
Nelson
E
E
D001781:Blood Component Removal / Q000295:instrumentation / Q000379:methods; D001803:Blood Transfusion / Q000295:instrumentation / Q000379:methods; D002469:Cell Separation / Q000295:instrumentation / Q000379:methods; D002499:Centrifugation, Density Gradient; D004905:Erythrocyte Aging; D017707:Erythrocyte Transfusion; D006801:Humans; D009821:Oils; D010795:Phthalic Acids; D013789:Thalassemia / Q000628:therapy
D009821:Oils; D010795:Phthalic Acids