[The cellular composition of the bronchoalveolar washing in experimental anthracosis].
Bronchoalveolar lavage (BAL) was performed in albino random-bred adult male rats with pneumoconiosis. Fibrotic reaction in the lungs was induced by inhalation coal dust during 6 months. BAL comprised 90.9 +/- 1.2% of macrophages; 4.4 +/- 0.8% of neutrophils and 4.5 +/- 1.0% of lymphocytes. The total cell number in BAL was higher (over 59%) in animals with pneumoconiosis. The number of cells on alveolar surface of the lungs was also higher. Fibrotic reaction in the lungs is probably directly related with the increased number of vital macrophages in the lung.
Romanova
L K
LK
Kabulov
Sh M
ShM
Mladkovskaia
T B
TB
D000818:Animals; D000874:Anthracosilicosis / Q000473:pathology*; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D002908:Chronic Disease; D003094:Collagen / Q000032:analysis; D007958:Leukocyte Count / Q000187:drug effects; D008168:Lung / Q000032:analysis / Q000187:drug effects / Q000473:pathology; D008297:Male; D009929:Organ Size / Q000187:drug effects; D010587:Phagocytosis; D051381:Rats
D003094:Collagen
Kletochnyĭ sostav bronkhoal'veoliarnogo smyva pri éksperimental'nom antrakoze.