title: Structural analysis of 21-hydroxypregn-4-ene-3,20-dione (deoxycorticosterone) derivative compounds. Part II: Proton NMR spectra.
abstract: Complete analysis of the proton nuclear magnetic resonance spectrum of desoxycorticosterone (DOC) has been made using selective double irradiation, two-dimensional experiments, relaxation rate, and nuclear Overhauser effect measurements in order to specify the structure and conformation of products encountered during the preparation of the specific antigen DOC-bovine serum albumin (BSA). It has been shown that DOC has the normal P conformation with ring A half-chair, and ring B chair. This confirms results previously obtained by circular dichroism measurements.
authors.affiliation: Laboratoire de Chimie Analytique II, Hopital de l'Antiquaille, Universite Claude Bernard Lyon, France.
authors.forename: L
authors.initials: L
authors.lastname: Kouadio
authors.forename: P
authors.initials: P
authors.lastname: Bernard
authors.forename: J F
authors.initials: JF
authors.lastname: Sabot
authors.forename: M M
authors.initials: MM
authors.lastname: Petit-Ramel
authors.forename: C M
authors.initials: CM
authors.lastname: Barbier
authors.forename: H J
authors.initials: HJ
authors.lastname: Pinatel
mesh_terms: D003900:Desoxycorticosterone / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation
chemical_list: D003900:Desoxycorticosterone