title: Marked cerebrospinal fluid collection associated with hepatic failure.
abstract: We report two cases with abnormal CSF accumulation in the cranium. One case had marked dilatation of the ventricular system, for which a ventriculoperitoneal shunt was carried out. The shunt was not beneficial and it turned out that the patient was suffering from ornithine transcarbamylase deficiency. The second case developed marked subdural effusion after fulminating hepatic failure and septicemia, for which drainage of the subdural space and subsequent insertion of Ommaya reservoirs were carried out. In spite of successful CSF control, the outcome was bad, both cases being incapacitated due to severe encephalopathy probably caused by hyperammonemia. The results of serial computed tomographic follow-up are presented.
authors.affiliation: Department of Neurosurgery, University of Tsukuba, Ibaraki, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Enomoto
authors.forename: M
authors.initials: M
authors.lastname: Hashikawa
authors.forename: T
authors.initials: T
authors.lastname: Nose
authors.forename: Y
authors.initials: Y
authors.lastname: Maki
authors.forename: K
authors.initials: K
authors.lastname: Hamano
authors.forename: N
authors.initials: N
authors.lastname: Nakamura
mesh_terms: D058186:Acute Kidney Injury / Q000150:complications*; D001927:Brain Diseases / Q000134:cerebrospinal fluid* / Q000000981:diagnostic imaging / Q000209:etiology; D002555:Cerebrospinal Fluid / Q000378:metabolism*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D018805:Sepsis / Q000209:etiology*; D014057:Tomography, X-Ray Computed