title: [Familial studies of patients with hereditary angioedema].
abstract: 25 families with 607 members were studied. 165 persons of them suffer from hereditary angioneurotic edema and 28 persons had died from this disease. The clinical forms of the disease are discussed. A classification of angioneurotic edema caused by C-inactivator deficiency is presented. The importance of the examination of C1 inactivator (quantitatively and qualitatively) and of C4 complement fraction in patients with hereditary angioneurotic edema is pointed out.
authors.forename: B
authors.initials: B
authors.lastname: Bozhkov
authors.forename: K
authors.initials: K
authors.lastname: Nikolov
authors.forename: M
authors.initials: M
authors.lastname: Baleva
mesh_terms: D000293:Adolescent; D000328:Adult; D000799:Angioedema / Q000145:classification / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D003174:Complement C1 Inactivator Proteins / Q000097:blood / Q000172:deficiency; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D006801:Humans; D008875:Middle Aged
chemical_list: D003174:Complement C1 Inactivator Proteins; D003176:Complement C3; D003181:Complement C4
vernacular_title: Familni prouchvaniia na bolni ot nasledstven angioedem.