title: Trehalase deficiency in Greenland.
abstract: Small-intestinal surgical biopsy specimens from 97 adult Greenlanders showed an incidence of trehalase deficiency in at least 8%. Trehalose tolerance tests performed in three individuals with low trehalase activity (6 IU/g protein) showed no increase in the blood glucose concentration. Three trehalase-deficient patients had lactase deficiency too. Trehalase deficiency is not considered to have any significance from a nutritional point of view.
authors.affiliation: Medical-Gastroenterological Dept. F, Gentofte Hospital, University of Copenhagen, Denmark.
authors.forename: E
authors.initials: E
authors.lastname: Gudmand-Høyer
authors.forename: H J
authors.initials: HJ
authors.lastname: Fenger
authors.forename: H
authors.initials: H
authors.lastname: Skovbjerg
authors.forename: P
authors.initials: P
authors.lastname: Kern-Hansen
authors.forename: P R
authors.initials: PR
authors.lastname: Madsen
mesh_terms: D000328:Adult; D005260:Female; D006116:Greenland; D006801:Humans; D007413:Intestinal Mucosa / Q000201:enzymology; D004930:Inuit; D008297:Male; D014198:Trehalase / Q000172:deficiency*
chemical_list: D014198:Trehalase