[Studies of complex lipids. Synthesis of ionophore derivatives of diphosphatidylglycerol (cardiolipin)].
Synthesis of cardiolipin analogues containing an ionophore residue in the fatty acid moiety is described. The ionophore, dibenzo-18-crown-6, has been incorporated into second position of the glycerol residue by acylating mono- and dilysocardiolipin with a modified fatty acid anhydride. Lyso-derivatives of cardiolipin have been prepared by enzymatic hydrolysis of beef heart cardiolipin by snake venom phospholipase A2 (Naja naja oxiana).
Kuz'mina
Iu V
IuV
Kaplun
A P
AP
Shvets
V I
VI
Saenko
V A
VA
Egorova
E M
EM
D000215:Acylation; D002308:Cardiolipins / Q000138:chemical synthesis* / Q000276:immunology; D055598:Chemical Phenomena; D002621:Chemistry; D004797:Enzyme-Linked Immunosorbent Assay; D007476:Ionophores / Q000138:chemical synthesis*; D008051:Lipid Bilayers
D002308:Cardiolipins; D007476:Ionophores; D008051:Lipid Bilayers
Issledovaniia v oblasti slozhnykh lipidov. Sintez ionofornykh proizvodnykh difosfatidilglitserina (kardiolipina).