Establishment and characterization of an intracerebrally transplanted tumor line, induced experimentally in the spinal cord.
Transplanted tumor lines are useful to study open questions in human pathology and clinical research, particularly with the evaluation of therapeutic measures. Transplantation tumor lines derived from neoplasms in the nervous system originally induced with resorptive carcinogens are considered to be useful for these purposes. In this study observations on the histological pattern of original and intracerebrally transplanted new induced spinal cord tumors, mainly in early passages, has been investigated with the aim to improve the usefulness of the experimental model.
Mennel
H D
HD
Department of Neuropathology, Medical Center of Pathology, University of Marburg, FRG.
D000818:Animals; D001932:Brain Neoplasms / Q000473:pathology*; D002460:Cell Line; D005038:Ethylnitrosourea; D005260:Female; D009368:Neoplasm Transplantation; D009423:Nervous System Neoplasms / Q000139:chemically induced / Q000473:pathology*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013120:Spinal Cord Neoplasms / Q000473:pathology*
D005038:Ethylnitrosourea