Laser Raman spectroscopic study of hereditary cataractous lenses in ICR/f-strain rat.
The lenses of ICR/f-strain rats with hereditary cataract were monitored in situ by laser Raman spectroscopy. The lenses used were within the age of 3-10 weeks before lens opacification became manifest. The reduction of protein SH group content and the increase of protein S-S bond content were observed in ICR/f rats in the precataractous stage. No significant change in the water content was observed.
Mizuno
A
A
Department of Biochemistry, Jikei University School of Medicine, Tokyo, Japan.
Kanematsu
E H
EH
Suzuki
H
H
Ihara
N
N
D000367:Age Factors; D000818:Animals; D002386:Cataract / Q000175:diagnosis* / Q000235:genetics; D004220:Disulfides / Q000032:analysis; D007834:Lasers; D007908:Lens, Crystalline / Q000032:analysis*; D051381:Rats; D013059:Spectrum Analysis, Raman
D004220:Disulfides