title: The polymorphism of HLA antigens in the Chinese.
abstract: Remarkable differences were observed in antigen frequencies (AF), gene frequencies (GF) and haplotype frequencies (HF) when 2441 healthy Chinese individuals representing nine different ethnic groups and living in 14 different geographic locations were examined for the genetic distribution of the various HLA Class I and II markers. A sizable number of individuals of each ethnic group within each of the three major categories of the Chinese population, namely, Hans, Mongols, and Southern minorities, have been studied here, providing useful population statistics for applications such as determination of probabilities of paternity, comparisons for HLA and disease associations, and anthropologic studies.
authors.affiliation: American Red Cross Blood Services, Rockville, MD.
authors.forename: T D
authors.initials: TD
authors.lastname: Lee
authors.forename: T M
authors.initials: TM
authors.lastname: Zhao
authors.forename: R
authors.initials: R
authors.lastname: Mickey
authors.forename: Y P
authors.initials: YP
authors.lastname: Sun
authors.forename: G
authors.initials: G
authors.lastname: Lee
authors.forename: C X
authors.initials: CX
authors.lastname: Song
authors.forename: D Z
authors.initials: DZ
authors.lastname: Cheng
authors.forename: S
authors.initials: S
authors.lastname: Zhou
authors.forename: S Q
authors.initials: SQ
authors.lastname: Ding
authors.forename: D X
authors.initials: DX
authors.lastname: Cheng
mesh_terms: D002681:China; D005787:Gene Frequency; D008040:Genetic Linkage; D005828:Genetics, Population; D006680:HLA Antigens / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D011110:Polymorphism, Genetic; D013223:Statistics as Topic
chemical_list: D006680:HLA Antigens