Responses of the retinal pigment epithelium of the mouse after acute loss of blood.
Albino mice were bled through the hearts by cardiac puncture and 1/2, 1/3 and 1/4 mls of blood were taken out from 3 groups of animals. respectively. Half of the experimental animals were reinfused with 5% dextrose 1 h after bleeding. All were killed either 2, 5, 9, 24, 48 or 72 h after bleeding, and the phagosome numbers per 5 pigment cells counted and compared with control retinae. A severe decrease was evident after bleeding and the decrease leveled off 48 h afterwards. Reinfusion with dextrose had a positive beneficial effect.
Li
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WW
Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T.
Yew
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DT
D000818:Animals; D007511:Ischemia / Q000473:pathology / Q000503:physiopathology*; D051379:Mice; D008813:Mice, Inbred ICR; D010587:Phagocytosis; D010588:Phagosomes / Q000648:ultrastructure; D010786:Photoreceptor Cells / Q000473:pathology; D010857:Pigment Epithelium of Eye / Q000473:pathology / Q000503:physiopathology*; D012160:Retina / Q000473:pathology / Q000503:physiopathology; D012374:Rod Cell Outer Segment / Q000473:pathology / Q000503:physiopathology