Polymorphism of debrisoquine hydroxylation among Finns and Lapps.
Debrisoquine hydroxylation polymorphism was studied in 155 Finns and 70 Lapps. The frequency of the poor metabolizer phenotype was 3.2% among Finns (95% confidence interval 0.4-6.0%) and 8.6% among Lapps (95% confidence interval 2.0-15.1%).
Arvela
P
P
Department of Pharmacology, University of Oulu, Finland.
Kirjarinta
M
M
Kirjarinta
M
M
Kärki
N
N
Pelkonen
O
O
D003647:Debrisoquin / Q000378:metabolism* / Q000652:urine; D005387:Finland; D006801:Humans; D006900:Hydroxylation; D007546:Isoquinolines / Q000378:metabolism*; D010641:Phenotype; D011110:Polymorphism, Genetic; D012537:Scandinavian and Nordic Countries
D007546:Isoquinolines; D003647:Debrisoquin