title: Chronological variation in chemical composition of urinary calculi between 1965-68 and 1982-86 in north western India.
abstract: The chemical composition of 210 urinary calculi either spontaneously passed or surgically removed during January 1965-December 1968 was compared with the chemical composition of 1338 urinary calculi received during July 1982-June 86. The proportion of vesical calculi had significantly decreased from 30.48% (n = 64) during 1965-68 to 8.37% (n = 112), during 1982-86 (p less than 0.001). During 1965-68, magnesium was present in 16%, ammonium in 31% and urate in 33% of vesical calculi. But during 1982-86, the percentage of vesical calculi containing magnesium and ammonium was nil (p less than 0.001), but 76.8% of vesical calculi contained urate (p less than 0.001). Similarly, during 1965-68, 35.6% of renal calculi containing magnesium, 20% contained ammonium, 13.6% contained carbonate and urate was present in 32.2% of renal calculi. In contrast during 1982-86, magnesium was detected in only 0.24% of renal calculi (p less than 0.001), ammonium in 0.16% (p less than 0.001) and carbonate in 3.9% (p less than 0.001) but 57.4% of renal calculi contained urate (p less than 0.001).
authors.affiliation: Department of Biochemistry Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Thind
authors.forename: H
authors.initials: H
authors.lastname: Sidhu
authors.forename: R
authors.initials: R
authors.lastname: Nath
authors.forename: G C
authors.initials: GC
authors.lastname: Malakandaiah
authors.forename: S
authors.initials: S
authors.lastname: Vaidyanathan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000641:Ammonia / Q000032:analysis; D002119:Calcium Carbonate / Q000032:analysis; D002129:Calcium Oxalate / Q000032:analysis; D002130:Calcium Phosphates / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D007194:India; D008274:Magnesium / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012959:Socioeconomic Factors / Q000639:trends*; D014527:Uric Acid / Q000032:analysis; D014545:Urinary Calculi / Q000032:analysis*
chemical_list: D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; D002129:Calcium Oxalate; D014527:Uric Acid; C485838:calcium phosphate, monobasic, anhydrous; D000641:Ammonia; C020243:calcium phosphate; D002119:Calcium Carbonate; D008274:Magnesium; C485829:calcium phosphate, dibasic, anhydrous