Oxidation phenotyping in Chinese and Malay populations.
1. Debrisoquine hydroxylation phenotyping was carried out in 97 Chinese and 97 Malay healthy volunteers. 2. No poor metabolizer was found in the Chinese population. Using a metabolic ratio antimode of 10.0, two poor metabolizers were present amongst the Malays studied.
Lee
E J
EJ
Department of Pharmacology, National University of Singapore, Kent Ridge.
Nam
Y P
YP
Hee
G N
GN
D000328:Adult; D044466:Asian People; D002681:China / Q000208:ethnology; D003647:Debrisoquin / Q000378:metabolism*; D005260:Female; D006801:Humans; D006900:Hydroxylation; D007546:Isoquinolines / Q000378:metabolism*; D008296:Malaysia / Q000208:ethnology; D008297:Male; D010641:Phenotype
D007546:Isoquinolines; D003647:Debrisoquin