title: Paradoxical sleep deprivation applied two days after end of training retards learning.
abstract: Sprague-Dawley rats (N = 98) were trained in a 2-way shuttle shock avoidance task (50 trials/day for two consecutive days) and then subjected to a paradoxical sleep deprivation (PSD) regime beginning at least 24 hours after the last training session. Results from the various PSD groups indicated that a vulnerable PS window exists from 48-72 hours after the end of the last training session. PSD during this time period produced severe retention deficits. These results suggest the existence of a very long term posttraining PS involvement in the learning/memory process.
authors.affiliation: Department of Psychology, Trent University, Peterborough, Ontario, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Smith
authors.forename: G
authors.initials: G
authors.lastname: Kelly
mesh_terms: D000818:Animals; D003213:Conditioning, Psychological; D007858:Learning; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012892:Sleep Deprivation; D012895:Sleep, REM / Q000502:physiology*