Phagocytosis of microspheric hydrophile particles (MSHP) by peripheral blood glass-adherent phagocytes of newborns.
The phagocytic activity of glass-adherent peripheral blood leukocytes of 58 healthy term newborns and 19 adult donors was examined using a micromethod employing a new type of synthetic hydrophilic particles based on 2-hydroxyethylmethacrylate. It was found that both the proportion of actively phagocytosing cells and the number of engulfed particles within the cells was significantly lower in neonates as compared with adults.
Miler
I
I
Research Institute for the Care of Mother and Child, Prague.
Borte
M
M
Vondrácek
J
J
Braun
W
W
D002448:Cell Adhesion; D005898:Glass; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn / Q000276:immunology*; D008863:Microspheres; D010586:Phagocytes / Q000502:physiology*; D010587:Phagocytosis; D012995:Solubility