Cochlear blood flow in endolymphatic hydrops.
There is no animal model for Meniere's disease but by obliteration of the endolymphatic duct, endolymphatic hydrops may be achieved in several animal species. In order to measure the cochlear blood flow in ears with endolymphatic hydrops the endolymphatic duct was obliterated in 9 guinea pigs. The blood flow was measured with the microsphere method and the cochlear histology was studied. The regional and total blood flow was determined in the serially sectioned cochleas 2, 4 and 8 months after obliteration of the endolymphatic duct. No change in regional or total cochlear blood flow was observed in the hydropic ears.
Larsen
H C
HC
Department of Otolaryngology, Akademiska Sjukhuset, University of Uppsala, Sweden.
Albers
F
F
Jansson
B
B
Angelborg
C
C
Veldman
J
J
D000818:Animals; D003051:Cochlea / Q000098:blood supply*; D004711:Endolymphatic Duct / Q000502:physiology; D005260:Female; D006168:Guinea Pigs; D008575:Meniere Disease / Q000503:physiopathology*; D008863:Microspheres; D012039:Regional Blood Flow