[Preliminary study on the effect of 1% indomethacin eyedrops in surgery of glaucoma].
Indomethacin collyrium, a powerful inhibitor of prostaglandin synthesis, was used successfully in many applications. The authors evaluated its action in the surgery of glaucoma. Two groups of patients had a trabeculectomy. The first group received instillation of indomethacin; the second was a control group. Four parameters were evaluated and compared in both groups: 1. Inflammatory state of the anterior chamber (AC). 2. Anterior chamber depth. 3. Filtration bleb state. 4. Intra-ocular pressure. Indomethacin promotes the establishment of a good filtration bleb that yields on a lasting ocular hypotonia, thus improving the results.
Romdane
K
K
Service d'Ophtalmologie, Hôpital Universitaire, Tunisie.
Chachia
N
N
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage / Q000627:therapeutic use*; D007249:Inflammation / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000517:prevention & control*; D011184:Postoperative Period; D011292:Premedication
D009883:Ophthalmic Solutions; D007213:Indomethacin
Etude préliminaire de l'effet de l'indométacine collyre à 1% dans la chirurgie du glaucome.