Differential burst firing modes in neurons of the mammalian visual cortex in vitro.
The firing patterns of visual cortical neurons were studied by intracellular recording in in vitro guinea pig brain slices. On depolarization 57% of the cells exhibited tonic firing of action potentials while the remaining cells (43%) had a phasic component in their response. Phasic cells exhibited a large diversity in their burst characteristics as well as in the burst dependence on the membrane potential. Ionic conductances underlying burst generation appeared to be also diverse, thus bursting neurons in the visual cortex cannot be grouped in a single, homogeneous population.
Montoro
R J
RJ
I.D.N., UA 1199 C.N.R.S., Département des Neurosciences de la Vision, Université Pierre et Marie Curie, Paris, France.
López-Barneo
J
J
Jassik-Gerschenfeld
D
D
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D004558:Electric Stimulation; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D013779:Tetrodotoxin / Q000494:pharmacology; D014793:Visual Cortex / Q000502:physiology*
D013779:Tetrodotoxin