title: A new approach to neocyte transfusion: preliminary report.
abstract: A method has been developed using phthalate oils to quality control units of young red cells (neocytes). Neocytes prepared by the NEOCEL system have a mean young red cell enrichment of 90% with only 3.4% less than 80%. Neocytes prepared in a blood cell processor have an average enrichment of 81% with 27% less than 75%. Based on a 12 month period, the patients as a group have received an average of 14% fewer transfusions and an 18% decrease in red cells per kg/yr as compared to frozen red cells.
authors.affiliation: Department of Medicine, Children's Hospital, Boston, Massachusetts 02115.
authors.forename: S V
authors.initials: SV
authors.lastname: Kevy
authors.forename: M S
authors.initials: MS
authors.lastname: Jacobson
authors.forename: M
authors.initials: M
authors.lastname: Fosburg
authors.forename: M
authors.initials: M
authors.lastname: Renaud
authors.forename: A
authors.initials: A
authors.lastname: Scanlon
authors.forename: R
authors.initials: R
authors.lastname: Carmen
authors.forename: E
authors.initials: E
authors.lastname: Nelson
mesh_terms: D001781:Blood Component Removal / Q000295:instrumentation / Q000379:methods; D001803:Blood Transfusion / Q000295:instrumentation / Q000379:methods; D002469:Cell Separation / Q000295:instrumentation / Q000379:methods; D002499:Centrifugation, Density Gradient; D004905:Erythrocyte Aging; D017707:Erythrocyte Transfusion; D006801:Humans; D009821:Oils; D010795:Phthalic Acids; D013789:Thalassemia / Q000628:therapy
chemical_list: D009821:Oils; D010795:Phthalic Acids