title: Structural analysis of 21-hydroxypregn-4-ene-3,20-dione (deoxycorticosterone) derivative compounds. Part I: Synthesis and circular dichroism identification.
abstract: Deoxycorticosterone (DOC) derivative compounds (DOC, DOC 21-acetate, and 7-mercaptopropionic DOC) have been prepared and purified by high pressure liquid chromatography. Synthesis products have been identified, and three chromophores have been displayed by their n----II and II----II dichroic transitions. A normal half-chair conformation is favored in ring A.
authors.affiliation: Laboratoire de Chimie Analytique II, Hopital de l'Antiquaille, Universite Claude Bernard Lyon, France.
authors.forename: L
authors.initials: L
authors.lastname: Kouadio
authors.forename: P
authors.initials: P
authors.lastname: Bernard
authors.forename: J F
authors.initials: JF
authors.lastname: Sabot
authors.forename: M M
authors.initials: MM
authors.lastname: Petit-Ramel
authors.forename: C M
authors.initials: CM
authors.lastname: Barbier
authors.forename: H J
authors.initials: HJ
authors.lastname: Pinatel
mesh_terms: D002942:Circular Dichroism; D003900:Desoxycorticosterone / Q000031:analogs & derivatives* / Q000032:analysis* / Q000138:chemical synthesis; D006868:Hydrolysis; D008968:Molecular Conformation
chemical_list: C058405:desoxycorticosterone-7-mercaptopropionic acid; D003900:Desoxycorticosterone