Carcinoembryonic antigen levels in sera drawn 1 to 12 years before diagnosis of cervical malignancy.
We determined serum CEA and beta-HCG levels in women who developed cervical carcinoma 1 to 12 years after the serum samples were drawn. Only 32 diagnostic sera CEA and beta-HCG levels were found. However, the serum CEA levels of the carcinoma patients differed significantly from those of their matched controls, who remained cancer free during the following 8 to 12 years after serum withdrawal. The difference in CEA levels between cases and controls did not depend on the lag period between serum withdrawal and cancer diagnosis, the severity of underlying cervical disease, or smoking habits.
Aaran
R K
RK
Institute of Biomedical Sciences, University of Tampere, Finland.
Lehtinen
M
M
Knekt
P
P
Aromaa
A
A
Hakama
M
M
D000328:Adult; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D006063:Chorionic Gonadotropin / Q000097:blood*; D005260:Female; D006801:Humans; D012907:Smoking / Q000097:blood; D013997:Time Factors; D002578:Uterine Cervical Dysplasia / Q000097:blood* / Q000175:diagnosis
D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin