Prevention of second primary cancers in head and neck cancer patients: new perspectives.
Not all head and neck cancer patients have the same chance to develop second primary cancers. New evidence suggests that it is possible to select high-risk patients. Other new developments in Europe are intensive screening, not only during initial work-up but also during follow-up, and chemoprevention of second primaries by retinol and n-acetyl-cystein.
de Vries
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Department of Otolaryngology/Head & Neck Surgery, Free University Hospital, Amsterdam, The Netherlands.
Snow
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GB
D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D009362:Neoplasm Metastasis; D012307:Risk Factors