title: Application of allyloxycarbonyl group as a protecting group to oligodeoxyribonucleotide synthesis.
abstract: The allyloxycarbonyl (AOC) group, known as an efficient amino protective group in solution-phase synthesis of nucleotides, has been used for the first time in solid-phase oligonucleotide synthesis. The efficiency of the new procedure is compared with that of the conventional N-acyl protection.
authors.affiliation: Biological Science Institute, Nippon Zeon Co. Ltd., Kanagawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Mitsuhira
authors.forename: S
authors.initials: S
authors.lastname: Tahara
authors.forename: K
authors.initials: K
authors.lastname: Goto
authors.forename: Y
authors.initials: Y
authors.lastname: Hayakawa
authors.forename: R
authors.initials: R
authors.lastname: Noyori
mesh_terms: D000498:Allyl Compounds; D001483:Base Sequence; D007202:Indicators and Reagents; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000302:isolation & purification
chemical_list: D000498:Allyl Compounds; D007202:Indicators and Reagents; D009838:Oligodeoxyribonucleotides