Central motor program for relaxation of periesophageal diaphragm during the expulsive phase of vomiting.
Relaxation of the periesophageal diaphragm during expulsion in decerebrate cats was found to arise from central mechanisms rather than a reflex of peripheral origin. Reductions in periesophageal EMG activity during expulsion were similar before and after cervical vagotomy, which abolishes reflex relaxation of the periesophageal diaphragm following esophageal distension. Reduced activity was also observed in a phrenic nerve branch to the periesophageal region during 'fictive vomiting' in a paralyzed animal.
Miller
A D
AD
Rockefeller University, New York, NY 10021.
Lakos
S F
SF
Tan
L K
LK
D000818:Animals; D002415:Cats; D003655:Decerebrate State; D003964:Diaphragm / Q000294:innervation* / Q000502:physiology / Q000503:physiopathology; D004576:Electromyography; D009119:Muscle Contraction; D009126:Muscle Relaxation; D010791:Phrenic Nerve / Q000502:physiology / Q000503:physiopathology*; D012018:Reflex; D012119:Respiration; D014628:Vagotomy; D014839:Vomiting / Q000503:physiopathology*