title: [Study of the nonspecific effect of phosphocreatine disodium salt on the process of excitation conduction in acute myocardial ischemia].
abstract: The effect of phosphocreatine and phosphocreatinine disodium salts on excitation conduction in acute myocardial ischemia was investigated, using repeated short-term ischemia exposures of the isolated rabbit ventricular septum as a model. Considerable improvement of excitation conduction through ischemized myocardium, seen after the administration of phosphocreatine and phosphocreatinine salts, was shown to be associated with Na+ added to the perfusion medium. Phosphocreatine and phosphocreatinine effects on excitation conduction time and the septal force in control perfusion were related to both the addition of Na+ and the binding of Ca2+ by these agents in the perfusion medium.
authors.forename: L V
authors.initials: LV
authors.lastname: Rozenshtraukh
authors.forename: I A
authors.initials: IA
authors.lastname: Fleĭdervish
authors.forename: A I
authors.initials: AI
authors.lastname: Undrovinas
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Paiu
mesh_terms: D000208:Acute Disease; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000517:prevention & control*; D002118:Calcium / Q000494:pharmacology; D003327:Coronary Disease / Q000503:physiopathology*; D003470:Culture Media; D004558:Electric Stimulation; D006329:Heart Conduction System / Q000187:drug effects / Q000503:physiopathology*; D066298:In Vitro Techniques; D008297:Male; D010725:Phosphocreatine / Q000031:analogs & derivatives* / Q000494:pharmacology; D011817:Rabbits; D012964:Sodium / Q000494:pharmacology
chemical_list: D003470:Culture Media; D010725:Phosphocreatine; C025403:phosphocreatinine; D012964:Sodium; D002118:Calcium
vernacular_title: Izuchenie nespetsificheskogo deĭstviia dinatrievoĭ soli fosfokreatina na protsess provedeniia vozbuzhdeniia pri ostroĭ nshemii miokarda.