title: Dissolution of calcium fluoride in human saliva.
abstract: The dissolution behavior of calcium fluoride in saliva was investigated. Chemically pure calcium fluoride (200 mg) was equilibrated in 10 ml of either saliva or distilled water for 3 weeks or repeatedly exposed, at 15-min intervals, to 10 ml of fresh solutions of saliva, distilled water, or phosphate- or calcium-containing solutions. Calcium fluoride dissolved more readily in water than in saliva. The study confirmed that exposure to saliva caused formation of a dissolution-limiting layer and that this layer consists of surface-adsorbed phosphates and showed in addition that the dissolution rate was continuously reduced with time of exposure to saliva or phosphate buffer. Calcium fluoride-like material, formed on enamel by treatment with 2% NaF solution, was shown by scanning electron microscopy to have higher stability in saliva than in water after 3 weeks' incubation.
authors.affiliation: Department of Prosthetic Dentistry, Dental Faculty, University of Oslo, Norway.
authors.forename: E
authors.initials: E
authors.lastname: Saxegaard
authors.forename: F
authors.initials: F
authors.lastname: Lagerlöf
authors.forename: G
authors.initials: G
authors.lastname: Rølla
mesh_terms: D002118:Calcium / Q000032:analysis; D002124:Calcium Fluoride / Q000493:pharmacokinetics*; D003743:Dental Enamel / Q000378:metabolism / Q000648:ultrastructure; D005459:Fluorides / Q000032:analysis; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010710:Phosphates / Q000494:pharmacology; D012463:Saliva / Q000378:metabolism*; D012995:Solubility
chemical_list: D010710:Phosphates; D002124:Calcium Fluoride; D005459:Fluorides; D002118:Calcium