title: [Relative biological effectiveness of tritium oxide based on DNA destruction and thymus depletion in rats].
abstract: As estimated by DNA destruction and thymus depletion for 21 days of observation, relative biological effectiveness (RBE) of tritium oxide (RBE HTO), as compared to gamma-quanta (137Cs), was 3.1 +/- 0.2 and 3.1 +/- 0.3, respectively. On days 1, 3, 7, 10, 14, and 21 RBE HTO, for the same indices at minimum radiation doses, was about 6-2. As determined by T1/2 period of double-stranded DNA diminution and thymus cell depletion RBE HTO was 5.5 +/- 0.4.
authors.forename: G G
authors.initials: GG
authors.lastname: Rusinova
authors.forename: V A
authors.initials: VA
authors.lastname: Turdakova
mesh_terms: D000818:Animals; D002588:Cesium Radioisotopes; D004247:DNA / Q000528:radiation effects*; D004249:DNA Damage; D005720:Gamma Rays; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012062:Relative Biological Effectiveness; D013950:Thymus Gland / Q000528:radiation effects*; D014316:Tritium; D014867:Water
chemical_list: D002588:Cesium Radioisotopes; D014867:Water; D014316:Tritium; C033961:tritium oxide; D004247:DNA
vernacular_title: Otnositel'naia biologicheskaia éffektivnost' okisi tritiia po kriteriam destruktsii DNK i opustosheniia vilochkovoĭ zhelezy krys.