title: Systemic toxicity of botulinum toxin by intramuscular injection in the monkey.
abstract: Botulinum toxin (Oculinum) was injected intramuscularly into eight monkeys. The LD50 dose is estimated to be approximately 39 U/kg body weight. The lowest dose that caused systemic toxicity, 33 U/kg, was close to the fatal dose range, 38-42 U/kg.
authors.affiliation: Smith-Kettlewell Eye Research Institute, Pacific Presbyterian Medical Center, San Francisco, California.
authors.forename: A B
authors.initials: AB
authors.lastname: Scott
authors.forename: D
authors.initials: D
authors.lastname: Suzuki
mesh_terms: D000818:Animals; D001905:Botulinum Toxins / Q000633:toxicity*; D005260:Female; D007273:Injections, Intramuscular; D007928:Lethal Dose 50; D008252:Macaca fascicularis; D008297:Male; D010243:Paralysis / Q000139:chemically induced
chemical_list: D001905:Botulinum Toxins