[Mineral metabolism and tissue-specific cytotoxic activity of the blood serum in the progeny in chronic alcoholic intoxication of the progenitors].
Late sequelae of chronic alcoholic intoxication were studied in the 3rd generation of animals. The peculiarities of trace element and macronutrient balance and the offspring blood serum tissue-specific cytotoxic activity against brain, testes, thymus, are discussed in their relation to the nature of chronic alcoholic intoxication of the 1st generation on paternal, maternal and both sides. Characteristic features are shown for the indices under study in the offspring, including the chronic alcoholic intoxication in males of the 1st generation. These peculiarities suggest the possibility of a differentiated therapeutical approach to correction of alcoholic embryo-/fetopathy.
Skal'nyĭ
A V
AV
Semenov
A S
AS
Slavin
F I
FI
D000437:Alcoholism / Q000097:blood* / Q000276:immunology; D000818:Animals; D003602:Cytotoxicity, Immunologic; D004912:Erythrocytes / Q000378:metabolism; D005220:Fathers; D005260:Female; D006706:Homeostasis; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D014131:Trace Elements / Q000097:blood*
D014131:Trace Elements
Mineral'nyĭ obmen i tkanespetsificheskaia tsitotoksicheskaia aktivnost' syvorotki krovi u potomstva pri khronicheskoĭ alkogol'noĭ intoksikatsii predkov.