title: Patterns of serum glucose and galactose concentrations in term newborn infants after milk feeding.
abstract: Galactose and glucose concentrations were measured in peripheral blood in relation to ad libitum milk feeding in 11 healthy near-term infants. Galactose and glucose concentrations before feeding averaged 1.06 +/- 0.21 and 60.3 +/- 3.2 mg/dl, respectively. After feedings containing 0.76-2.68 g lactose/kg body weight, both galactose and glucose rose by approximately 35% Galactose concentrations rose by 0.72 +/- 0.10 mg/dl at 30 min after feeding, while glucose concentration rose by 23.3 +/- 2.5 mg/dl at 30 min after feeding. The 25-fold greater absolute increase in the concentration of glucose than galactose is consistent with efficient first-pass clearance of galactose by the neonatal liver.
authors.affiliation: Department of Pediatrics, University of Colorado School of Medicine, Denver.
authors.forename: C D
authors.initials: CD
authors.lastname: Siegel
authors.forename: J W
authors.initials: JW
authors.lastname: Sparks
authors.forename: F C
authors.initials: FC
authors.lastname: Battaglia
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D005260:Female; D005690:Galactose / Q000378:metabolism*; D005693:Galactosemias / Q000175:diagnosis; D006801:Humans; D007225:Infant Food; D007231:Infant, Newborn / Q000378:metabolism*; D008111:Liver Function Tests; D008297:Male; D008892:Milk / Q000378:metabolism*; D008895:Milk, Human / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D005690:Galactose