Growth hormone evaluation in Duchenne muscular dystrophy.
Growth hormone (GH) release with pharmacological tests and sleep test, somatomedin C and auxological features were studied in 10 patients affected by Duchenne Muscular Dystrophy. GH release in these patients seems to be lower than normal; moreover some of them are of short stature without an evident relationship with GH deficit. The possible significance of the data obtained is discussed, particularly in relation to the clinical course of the disease, and to current therapeutic trials with a GH release inhibitor (mazindol).
Merlini
L
L
Laboratorio di Neurofisiologia, Istituto Ortopedico Rizzoli, Bologna.
Granata
C
C
Ballestrazzi
A
A
Cornelio
F
F
Tassoni
P
P
Tugnoli
S
S
Cacciari
E
E
D001120:Arginine; D001827:Body Height; D002648:Child; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D007980:Levodopa; D008297:Male; D009136:Muscular Dystrophies / Q000378:metabolism*; D012890:Sleep
D007980:Levodopa; D013006:Growth Hormone; D001120:Arginine