title: Studies on early replication patterns in the marsupial Sminthopsis crassicaudata: no evidence for XY replication homologies.
abstract: We present here the first detailed replication banding study of a marsupial species using the BrdU-replication technique. A comparison of the structural and replication bands of the chromosomes of Sminthopsis crassicaudata clearly demonstrates that the replication behavior is the same as the described for the chromosomes of eutherians. The early replicating segments correspond to R-bands, whereas the late-replicating regions tend to be situated within Q- and C-bands. Use of this technique clearly reveals an early and late replicating X chromosome. The very small Y chromosome can be subdivided into two replication segments, but no replication homologies can be demonstrated between the X and Y chromosomes of S. crassicaudata.
authors.affiliation: Institut für Humangenetik und Anthropologie, Universität Freiburg i. Br., Federal Republic of Germany.
authors.forename: G
authors.initials: G
authors.lastname: Müller
authors.forename: D
authors.initials: D
authors.lastname: Hayman
authors.forename: W
authors.initials: W
authors.lastname: Schempp
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002871:Chromosome Banding; D004261:DNA Replication; D008394:Marsupialia / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D012730:Sex Chromosomes / Q000502:physiology*