title: Development of periodontal disease in a single flock of sheep: clinical signs, morphology of subgingival plaque and influence of antimicrobial agents.
abstract: The clinical development of broken mouth over a single reproductive year and the effect of two broad spectrum antibacterial agents upon it was followed in 72 Scottish Blackface ewes aged between two and three years. Using a number of dental health indices especially developed for the purpose, the amount of gingivitis, tooth movement, gum recession and pocketing were quantified and graphed for both the whole population and each group in the drug trial. All clinical features except movement fluctuated significantly with time, the fluctuations often being associated with nutritional or other environmental factors. Despite the extended use of large doses of two antimicrobial agents no significant reduction in the amount of clinical gingivitis or pocketing was evident.
authors.affiliation: Moredun Research Institute, Edinburgh.
authors.forename: J A
authors.initials: JA
authors.lastname: Spence
authors.forename: G U
authors.initials: GU
authors.lastname: Aitchison
authors.forename: J
authors.initials: J
authors.lastname: Fraser
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D003773:Dental Plaque / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D005881:Gingiva / Q000473:pathology; D008795:Metronidazole / Q000627:therapeutic use*; D010118:Oxytetracycline / Q000627:therapeutic use*; D010510:Periodontal Diseases / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D010512:Periodontal Index / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D013997:Time Factors
chemical_list: D008795:Metronidazole; D010118:Oxytetracycline