title: Toxicity of selected tremorgenic mycotoxins and related compounds to Spodoptera frugiperda and Heliothis zea.
abstract: A series of tremorgenic mycotoxins and related compounds were tested for oral toxicity to the fall armyworm (Spodoptera frugiperda) and corn earworm (Heliothis zea) by incorporation of materials into artificial diets and examining mortality and weights after 7 days. Significant mortality to both insect species was caused with dihydroxyaflavinine and roseotoxin B, while significant mortality to H. zea was also caused by penitrem A at 25 ppm. After 7 days, weighs of larvae treated with 25 ppm penitrem A, roseotoxin B, and verruculogen were less than 50% of controls for both insect species. Weights of H. zea larvae treated with 25 ppb of penitrem A were less than 50% those of control larvae. Relative toxicities of the tremorgens and related compounds to insects compared to vertebrates are discussed.
authors.affiliation: U.S. Department of Agriculture, Northern Regional Research Center, Peoria, IL 61604.
authors.forename: P F
authors.initials: PF
authors.lastname: Dowd
authors.forename: R J
authors.initials: RJ
authors.lastname: Cole
authors.forename: R F
authors.initials: RF
authors.lastname: Vesonder
mesh_terms: D000818:Animals; D005998:Glycine / Q000096:biosynthesis; D007313:Insecta / Q000187:drug effects*; D051379:Mice; D009183:Mycotoxins / Q000494:pharmacology*
chemical_list: D009183:Mycotoxins; D005998:Glycine