title: Effect of maternal intrapartum glucose therapy on neonatal blood glucose levels and neurobehavioral status of hypoglycemic term newborn infants.
abstract: Two groups of 45 term, vaginally delivered infants were studied to determine effect of maternal intrapartum glucose therapy on neonatal blood glucose level at birth and at one and 2 hours of age. Twenty-three infants whose mother received glucose infusion prior to delivery (study group) had a significantly higher mean cord blood glucose level, lower 2 hour blood glucose levels and about three times higher incidence of hypoglycemia (glucose level less than or equal to 2.2 mmol/l) as compared to 22 infants whose mothers did not receive any glucose or fluid therapy. Neurobehavioral evaluation of the infants at 1 and 2 hour demonstrated, a significant association between hypoglycemia and a low muscle tone score and a delayed habituation to various stimuli. Blood glucose levels must be routinely monitored in infants whose mother receive glucose infusion prior to delivery to detect and treat early neonatal hypoglycemia.
authors.affiliation: Department of Child Health, University of the West Indies, Kingston, Jamaica.
authors.forename: S
authors.initials: S
authors.lastname: Singhi
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D005440:Fluid Therapy; D005947:Glucose / Q000627:therapeutic use*; D006801:Humans; D007003:Hypoglycemia / Q000097:blood*; D007231:Infant, Newborn / Q000097:blood*; D007743:Labor, Obstetric; D008431:Maternal-Fetal Exchange; D009460:Neurologic Examination; D011247:Pregnancy; D011446:Prospective Studies; D012018:Reflex / Q000502:physiology; D013216:Reflex, Startle / Q000502:physiology
chemical_list: D001786:Blood Glucose; D005947:Glucose