A further examination of the effects of sertraline on voluntary ethanol consumption.
Previous work with the serotonin uptake blocker, sertraline, demonstrated that the drug suppressed the consumption of ethanol and saccharin as well as body weight gain. There is increasing evidence that many serotonergic agents such as agonists, releasing agents and uptake blockers, reduce food intake. Sertraline was found to have a robust anorexic action. In this paper evidence is presented which supports the hypothesis that the administration of serotonin uptake blockers reduce ethanol consumption as a secondary consequence of a suppression in food intake.
Gill
K
K
Centre for Studies in Behavioral Neurobiology, Concordia University, Montreal, Canada.
Filion
Y
Y
Amit
Z
Z
D015057:1-Naphthylamine / Q000031:analogs & derivatives / Q000494:pharmacology*; D000428:Alcohol Drinking / Q000187:drug effects*; D000704:Analysis of Variance; D000818:Animals; D004326:Drinking / Q000187:drug effects; D004435:Eating / Q000187:drug effects; D009281:Naphthalenes / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D020280:Sertraline; D013997:Time Factors; D014836:Volition
D009281:Naphthalenes; D015057:1-Naphthylamine; D020280:Sertraline