Intravoxel incoherent motion imaging using steady-state free precession.
IVIM MR imaging is a method which generates images of diffusion and perfusion in vivo. Until now, intravoxel incoherent motion (IVIM) images have been obtained using spin-echo sequences with extragradient pulses, resulting in long acquisition times (typically 2 x 8 min 32 s). A new method is proposed here, using steady-state free precession (SSFP), which allows IVIM images to be obtained in a couple of minutes. Phantom studies showed that the sensitivity of SSFP to IVIMs is much greater than that of spin echoes. In vivo images are shown.
Le Bihan
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Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892.
D001834:Body Water / Q000378:metabolism; D001921:Brain / Q000033:anatomy & histology; D002555:Cerebrospinal Fluid / Q000378:metabolism; D004058:Diffusion; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008953:Models, Anatomic; D012016:Reference Values