Biological study of triterpenequinones from celastraceae.
The cytostatic activity of several triterpenequinone methides isolated from Rzedowskia tolantonguensis and Maytenus horrida (Celastraceae) was evaluated against HeLa cell cultures. Their ID50 were determined and compared with those of other related compounds. A preliminary study of the antibacterial activity of the above triterpenequinone methides was also carried out.
Gonzáles
A G
AG
Centro de Productos Naturales Organicos Antonio González, Universidad de la Laguna, Canary Islands, Spain.
Ravelo
A G
AG
Bazzocchi
I L
IL
Jimenes
J
J
Gonzáles
C M
CM
Luis
J G
JG
Ferro
E A
EA
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D001419:Bacteria / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D006367:HeLa Cells; D006801:Humans; D010946:Plants, Medicinal / Q000032:analysis*; D011809:Quinones / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D011809:Quinones; D014315:Triterpenes