Familial megacalyces with autosomal recessive inheritance. Report of 3 affected siblings.
Three children with bilateral congenital megacalyces from a consanguinous marriage are reported. No renal abnormality was detected in the parents. Our observation supports the genetic nature of the disease. The ultrasonographic features of congenital megacalyces are described.
Lam
A H
AH
Department of Radiology, Children's Hospital Camperdown, Sydney, Australia.
D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D004108:Dilatation, Pathologic / Q000235:genetics; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D007670:Kidney Calices / Q000002:abnormalities*; D007682:Kidney Pelvis / Q000002:abnormalities*; D008297:Male; D010375:Pedigree