title: Short-latency autogenic inhibition (IB inhibition) in human spasticity.
abstract: The inhibitory effect of IB interneurons on motoneurons was tested in both legs of six hemiplegic adults. On the normal side, an inhibition of 10 ms, (14.6%) was observed in all cases and was similar to that described previously. On the spastic side, the same technique results in a facilitation of same duration reaching a maximum of 15%. Hence the IB inhibitory effect is, at least functionally, absent in spasticity. Disappearance of IB inhibition is an additional mechanism to be considered in interpreting spasticity.
authors.affiliation: University Department of Neurology, Hôpital de la Citadelle, Liège, Belgium.
authors.forename: P J
authors.initials: PJ
authors.lastname: Delwaide
authors.forename: E
authors.initials: E
authors.lastname: Oliver
mesh_terms: D000328:Adult; D000344:Afferent Pathways / Q000503:physiopathology; D000368:Aged; D001921:Brain / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000503:physiopathology*; D006181:H-Reflex; D006429:Hemiplegia / Q000503:physiopathology*; D006801:Humans; D007395:Interneurons / Q000502:physiology; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009128:Muscle Spasticity / Q000503:physiopathology*; D009132:Muscles / Q000294:innervation*; D009412:Nerve Fibers / Q000503:physiopathology; D009433:Neural Inhibition; D010525:Peripheral Nerves / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology*; D013116:Spinal Cord / Q000503:physiopathology