title: [Optimization of a method of determination of endogenous ethanol in the blood and tissues of man and experimental animals].
abstract: An improved procedure is described for estimation of endogenous ethanol in human and animal biological fluids using gas chromatographic analysis of equilibrated steam. Sensitivity of the procedure was as low as 0.05 mg/L and relative error--about 6%. Content of endogenous ethanol constituted from 0.08 mg/L to 1.30 mg/l (the mean value was 0.38 +/- 0.07 mg/L) in blood of healthy men which did not consume alcohol for a long time. In blood and tissues of white rats content of ethanol was equal to 0.06-1.32 mg/L and 0.07-3.12 mg/l, respectively.
authors.forename: S N
authors.initials: SN
authors.lastname: Shishkin
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Ostrovskiĭ
authors.forename: P S
authors.initials: PS
authors.lastname: Pron'ko
mesh_terms: D000818:Animals; D002849:Chromatography, Gas / Q000379:methods*; D000431:Ethanol / Q000032:analysis / Q000097:blood*; D006801:Humans; D008297:Male; D051381:Rats; D014018:Tissue Distribution
chemical_list: D000431:Ethanol
vernacular_title: Optimizatsiia tekhniki opredeleniia urovnia éndogennogo étanola v krovi i tkaniakh cheloveka i éksperimental'nykh zhivotnykh.