title: Sauvagine/urotensin I-like immunoreactivity in the brain of the dogfish, Scyliorhinus canicula.
abstract: The localization of a sauvagine (SV)/urotensin I (UI)-like material in the brain of the dogfish, Scyliorhinus canicula, was studied by immunohistochemical techniques, employing an antiserum raised in rabbit against synthetic SV which widely cross-reacts with UI. Positive cell bodies and nerve fibers were identified in the dorsocaudal hypothalamic region of the tuberculum posterius, in the nucleus sacci vasculosi and nucleus tuberculi posterioris. A dense network of immunoreactive axons was shown in the whole tuberculum posterius. These findings support the view that SV/UI-like peptides may be involved in neuromodulatory functions throughout the brain of cartilaginous fish.
authors.affiliation: Istituto di Anatomia Comparata, Università di Genova, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Vallarino
authors.forename: I
authors.initials: I
authors.lastname: Ottonello
authors.forename: L
authors.initials: L
authors.lastname: D'Este
authors.forename: T
authors.initials: T
authors.lastname: Renda
mesh_terms: D029845:Amphibian Proteins; D000818:Animals; D001921:Brain / Q000166:cytology / Q000378:metabolism*; D004284:Dogfish / Q000378:metabolism*; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D036361:Peptide Hormones; D010455:Peptides / Q000378:metabolism*; D012754:Sharks / Q000378:metabolism*; D014579:Urotensins / Q000378:metabolism*
chemical_list: D029845:Amphibian Proteins; D036361:Peptide Hormones; D010455:Peptides; D014579:Urotensins; C025727:sauvagine; C029676:urotensin I