The length dependence of the series elasticity of pig bladder smooth muscle.
Strips of urinary bladder smooth muscle were subjected to a series of quick release measurements. Each measurement consisted of several releases and resets to the original length, made during one contraction. The complete length-force characteristic of series elasticity was quantified by estimating H, the amplitude of quick release necessary to reduce the active force to exactly zero, and Db, a measure for the deviation of the characteristic from a straight line. By measuring a series of contractions at increasing stretched strip lengths, the length dependence of these parameters was studied. It was found that H depends linearly on stretched strip length. On average H/length amounted to 0.04. Db decreased when strips were stretched, i.e. a straight line was more closely approximated. Both parameter dependencies support the concept of two separate elastic mechanisms, a linear true passive elasticity in series with a non-linear elasticity in the cross-bridges. For the latter, H amounts to 3.8% of the initial strip length.
Van Mastrigt
R
R
Department of Urology, Erasmus University, Rotterdam, The Netherlands.
D000818:Animals; D004548:Elasticity; D009130:Muscle, Smooth / Q000033:anatomy & histology / Q000502:physiology*; D013552:Swine / Q000502:physiology*; D001743:Urinary Bladder / Q000033:anatomy & histology