[Ofloxacin for the treatment of chlamydial urethritis].
The effect of Ofloxacin administered orally 600 mg everyday for 14 days was evaluated in 20 male patients with Chlamydial urethritis, in whom Chlamydia was identified from urethral secretion by immunohistochemical technique using monoclonal primary antibody specific for all known serotypes of Chlamydia trachomatis and psittaci. 19 out of the 20 patients showed an improvement of subjective and/or objective symptoms after the treatment. The Chlamydia reaction turned to negative in 13 patients and to (+/-) in another patient. The overall clinical effect was excellent in 7, good in 6 and poor in 7, showing a effective rate of 65%. No side effects were observed.
Yuri
K
K
Department of Urology, Kyoto Prefectural University of Medicine.
Terasaki
T
T
Kitamori
T
T
Azuma
Y
Y
Watanabe
H
H
Araki
H
H
D000328:Adult; D000942:Antigens, Bacterial / Q000032:analysis; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000276:immunology; D002692:Chlamydia trachomatis / Q000276:immunology; D004341:Drug Evaluation; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D015242:Ofloxacin / Q000627:therapeutic use*; D014526:Urethritis / Q000188:drug therapy* / Q000276:immunology
D000942:Antigens, Bacterial; D015242:Ofloxacin