[Indicators of glycated proteins in the diagnosis of diabetes. Use in populations with a high prevalence of hemoglobinopathies].
The authors compare the relative validity of HbA1c and fructosamine as indices of long-term blood glucose levels in population with a common occurrence of haemoglobinopathies. HbA1c levels in patients with haemoglobinopathies do not reflect the glucidic status of patients when compared to HbA1c levels in reference population. Validity of the fructosamine assay allows its potential use as a mass screening test for diabetes in these populations (USA, Africa, Caribbean...).
Pileire
B
B
Laboratoire de Biochimie, INSERM-SASD, Centre Hospitalier Régional et Universitaire, Pointe a Pitre, Guadeloupe.
Moutet
J P
JP
Bangou
J
J
Ragoucy-Sengler
C M
CM
D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000097:blood* / Q000175:diagnosis; D019270:Fructosamine; D006442:Glycated Hemoglobin / Q000032:analysis*; D006031:Glycosylation; D006453:Hemoglobinopathies / Q000097:blood*; D006595:Hexosamines; D006801:Humans; D006943:Hyperglycemia / Q000097:blood
D001786:Blood Glucose; D019270:Fructosamine; D006442:Glycated Hemoglobin; D006595:Hexosamines
Marqueurs de la glycation des protéines dans le dépistage du diabéte. Application aux populations à forte prévalence d'hémoglobinopathies.