[Dehydrogenase activity of the liver in rats following 30 days' exposure to hypergravity].
In response to 30-day centrifugation at 2.0 or 1.1 G rats showed decreases in liver mitochondrial and cytoplasmic NAD-dependent malate dehydrogenase and NADH-dependent isocitrate dehydrogenase. These changes can be considered as a decline of energetic and biosynthetic processes in the liver in response to hypodynamics and hypergravity. After cessation of centrifugation the liver enzymes returned to the pretest level: cytoplasmatic dehydrogenases on the 2nd day and mitochondrial malate dehydrogenase on the 7th day of recovery.
Vetrova
E G
EG
Krasnov
I B
IB
D000818:Animals; D003593:Cytoplasm / Q000201:enzymology; D006112:Gravitation; D007521:Isocitrate Dehydrogenase / Q000378:metabolism*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008291:Malate Dehydrogenase / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000201:enzymology; D051381:Rats; D013997:Time Factors
D007770:L-Lactate Dehydrogenase; D008291:Malate Dehydrogenase; D007521:Isocitrate Dehydrogenase; C039355:isocitrate dehydrogenase (NADP+)
Aktivnost' degidrogenaz pecheni krys posle 30-sutochnogo vozdeĭstviia povyshennoĭ sily tiazhesti.