title: Micro-angiopathic haemolysis, thrombocytopenia and nephrotic syndrome associated with membranous nephropathy in a Vietnamese boy.
abstract: The unique association of idiopathic diffuse membranous nephropathy and micro-angiopathic haemolytic anaemia and thrombocytopenia is described. A 7 year old Vietnamese boy with a 1-month history of anaemia resistant to oral iron supplements presented with acute onset of nephrotic syndrome. Investigations revealed a micro-angiopathic haemolytic anaemia and thrombocytopenia. There was no associated oliguria or uraemia. Diffuse membranous nephropathy was diagnosed by renal biopsy. Apart from a fourfold rise in enterovirus titres, no underlying cause for the haematological or glomerular abnormalities was found. There was an apparent, partial haematological response to fresh frozen plasma infusions, but not to Vitamin E.
authors.affiliation: Children's Hospital, Camperdown, New South Wales, Australia.
authors.forename: D T
authors.initials: DT
authors.lastname: McDonald
authors.forename: L P
authors.initials: LP
authors.lastname: Roy
mesh_terms: D000743:Anemia, Hemolytic / Q000150:complications*; D002648:Child; D005500:Follow-Up Studies; D015433:Glomerulonephritis, Membranous / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000209:etiology* / Q000473:pathology; D013921:Thrombocytopenia / Q000150:complications*