N-oxidation, N-demethylation, and excretion of pefloxacin by the turtle Pseudemys scripta elegans.
Pefloxacin is minimally absorbed by the gastrointestinal tract of the turtle Pseudemys scripta elegans and then N-oxidised and N-demethylated. Pefloxacin is excreted within one hour after being given orally to the turtles.
Vree
T B
TB
Department of Clinical Pharmacy, Sint Radboud hospital, Nijmegen, The Netherlands.
Vree
J B
JB
Baars
I M
IM
Hekster
Y A
YA
Nouws
J F
JF
D000818:Animals; D010084:Oxidation-Reduction; D015366:Pefloxacin / Q000378:metabolism / Q000493:pharmacokinetics* / Q000652:urine; D014426:Turtles / Q000378:metabolism*
D015366:Pefloxacin