Properties and characteristics of a bacteriocin-like substance produced by Propionibacterium acnes isolated from dental plaque.
A cell-associated bacteriocinlike substance with an approximate molecular weight of 78,000 was isolated from an oral isolate of Propionibacterium acnes. The substance was bacteriostatic and was active against both gram-positive and gram-negative anaerobes. Lysozyme inhibited the activity of the bacteriocinlike substance at low ionic strength.
Paul
G E
GE
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68105.
Booth
S J
SJ
D001430:Bacteriocins / Q000032:analysis / Q000037:antagonists & inhibitors / Q000096:biosynthesis* / Q000494:pharmacology; D003773:Dental Plaque / Q000382:microbiology*; D006089:Gram-Negative Anaerobic Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D011402:Pronase / Q000494:pharmacology; D011425:Propionibacterium acnes / Q000378:metabolism*; D014357:Trypsin / Q000494:pharmacology
D001430:Bacteriocins; D014357:Trypsin; D011402:Pronase