A glycopeptide from adenocarcinoma tissue of human lung.
A glycopeptide from adenocarcinoma tissue of human lung was extracted by protein digestion with papain (EC 3.4.22.2) and trypsin (EC 3.4.21.4). This component was isolated by Pevikon block electrophoresis. It possessed hexose, glucosamine, fucose, galactosamine, and sialic acid. In its carbohydrate composition and also the abundance of threonin in the peptide moiety it was quite similar to the glycoprotein from gastrointestinal tract. The physical characteristic of the two, such as their optical rotation and viscosity, were also very similar each other.
Masuda
H
H
Third Department of Internal Medicine, University of Occupational and Environmental Health, School of Medicine, Fukuoka, Japan.
Ozeki
T
T
D000230:Adenocarcinoma / Q000032:analysis*; D000596:Amino Acids / Q000032:analysis; D006020:Glycopeptides / Q000302:isolation & purification*; D006025:Glycosaminoglycans / Q000032:analysis; D006601:Hexoses / Q000032:analysis; D006801:Humans; D008168:Lung / Q000032:analysis; D008175:Lung Neoplasms / Q000032:analysis*; D009439:Neuraminidase; D012016:Reference Values; D012794:Sialic Acids / Q000032:analysis
D000596:Amino Acids; D006020:Glycopeptides; D006025:Glycosaminoglycans; D006601:Hexoses; D012794:Sialic Acids; D009439:Neuraminidase