title: CA 125 in the monitoring of response to chemotherapy of ovarian carcinoma.
abstract: CA 125 serum levels were assessed in 23 patients undergoing chemotherapy for advanced epithelial ovarian carcinoma (EOC). Rising, falling and unchanged levels correlated with disease in 21 out of 23 (95%) cases. Ten out of 11 patients who showed objective response to chemotherapy had a decrease in antigen levels. Two out of 3 patients with stable disease had unchanged values. Progression was always associated with rising levels. CA 125 is a reliable marker for monitoring response to chemotherapy in advanced epithelial ovarian carcinoma.
authors.affiliation: Laboratory Service, Oncologic Institute, Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Quaranta
authors.forename: V
authors.initials: V
authors.lastname: Lorusso
authors.forename: M
authors.initials: M
authors.lastname: Coviello
authors.forename: G
authors.initials: G
authors.lastname: Micelli
authors.forename: A
authors.initials: A
authors.lastname: Casamassima
mesh_terms: D000328:Adult; D000368:Aged; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000276:immunology
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate