[Hemodynamic and metabolic effects of adenosine in experimental myocardial infarction].
Adenosine, administered intravenously (0.25 mg/kg-1/min-1) to rabbits with experimental myocardial infarction, produced a drop in arterial pressure and total peripheral resistance, normalized stroke volume, increased ATP content at the margin of the infarcted area, and reduced LDG activity and increased SDG activity in the ischemized region.
Eliseev
V V
VV
Krylova
I B
IB
Ovchinnikova
A G
AG
Evdokimova
N R
NR
Prokopenko
V M
VM
D000241:Adenosine / Q000627:therapeutic use; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D004353:Drug Evaluation, Preclinical; D006439:Hemodynamics / Q000187:drug effects*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000503:physiopathology; D009206:Myocardium / Q000378:metabolism*; D011817:Rabbits; D013385:Succinate Dehydrogenase / Q000378:metabolism
D000255:Adenosine Triphosphate; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D000241:Adenosine
Gemodinamicheskie i metabolicheskie éffekty adenozina pri eksperimental'nom infarkte miokarda.