title: Aortic valve replacement in the second trimester of pregnancy: a case report.
abstract: A 36 year old woman with left heart failure and right-sided hemiparesis due to endocarditis of the aortic valve underwent urgent aortic valve replacement during the 24th week of gestation. High-flow high-pressure normothermic perfusion during cardiopulmonary bypass was performed. Peri-operative fetal heart rate and uterine contractions were monitored. Severe fetal heart rate decelerations and loss of variability as well as uterine contractions were observed during surgery. Uterine contractions were treated medically. Pregnancy was carried to term and a healthy baby was delivered vaginally. The effect of the nonpulsating cardiac pump during extracorporeal circulation on the fetus will be discussed. Recommendations for the peri-operative management of the fetal unit are made.
authors.affiliation: Department of Obstetrics and Gynaecology, Catharina Hospital, Eindhoven, The Netherlands.
authors.forename: P N
authors.initials: PN
authors.lastname: Mooij
authors.forename: P A
authors.initials: PA
authors.lastname: de Jong
authors.forename: J H
authors.initials: JH
authors.lastname: Bavinck
authors.forename: H H
authors.initials: HH
authors.lastname: Korsten
authors.forename: J J
authors.initials: JJ
authors.lastname: Bonnier
authors.forename: J N
authors.initials: JN
authors.lastname: Berendes
mesh_terms: D000328:Adult; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D001145:Arrhythmias, Cardiac / Q000209:etiology* / Q000503:physiopathology; D004562:Electrocardiography; D004696:Endocarditis / Q000150:complications*; D005260:Female; D005315:Fetal Diseases / Q000209:etiology* / Q000503:physiopathology; D006340:Heart Rate, Fetal; D006801:Humans; D007431:Intraoperative Complications; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology / Q000601:surgery*; D011262:Pregnancy Trimester, Second