title: Sudden hearing loss in an adolescent following a single dose of cisplatin.
abstract: Progressive hearing loss after cisplatin therapy is relatively frequent, specially in older patients, but it is less common in children and in acute form. The case of a 17-year-old patient with an intracranial tumor who suffered sudden deafness after a single course of cisplatin is presented. This patient had a previously documented very good hearing up to 20 kHz. Although it has been suggested that children with irradiated brain tumors may have an increased susceptibility to cisplatin-induced hearing loss, in this case the patient had not been subjected to radiotherapy.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Doménech
authors.forename: P
authors.initials: P
authors.lastname: Santabarbara
authors.forename: M
authors.initials: M
authors.lastname: Carulla
authors.forename: J
authors.initials: J
authors.lastname: Traserra
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000188:drug therapy*; D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D004407:Dysgerminoma / Q000188:drug therapy*; D003639:Hearing Loss, Sudden / Q000139:chemically induced*; D006801:Humans; D008297:Male
chemical_list: D002945:Cisplatin