title: [Clinical study of imipenem/cilastatin sodium in the perinatal period].
abstract: A clinical study was carried out on imipenem/cilastatin sodium (IPM/CS) in the perinatal period, and the results obtained are summarized as follows. IPM/CS was given to 5 cases with puerperal intrauterine infection and 2 with puerperal fever. The clinical efficacies were evaluated as good in 6 cases and poor in 1. The clinical efficacy rate was 85.7%. In a bacteriological examination, 9 strains were isolated from 6 cases, and 7 strains were eradicated with an eradication rate of 77.8%. No side effects were observed in any of the cases treated with IPM/CS.
authors.affiliation: Department of Obstetrics and Gynecology, Kyoto Prefectual University of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: J
authors.initials: J
authors.lastname: Yasuda
authors.forename: M
authors.initials: M
authors.lastname: Kanao
authors.forename: H
authors.initials: H
authors.lastname: Okada
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000188:drug therapy*; D015377:Cilastatin / Q000008:administration & dosage* / Q000627:therapeutic use; D004341:Drug Evaluation; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004716:Endometritis / Q000188:drug therapy; D005260:Female; D006801:Humans; D015378:Imipenem / Q000008:administration & dosage* / Q000627:therapeutic use; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy*
chemical_list: D015377:Cilastatin; D015378:Imipenem