title: Roots and calibers of the human coronary arteries.
abstract: The anatomical structure of the coronary-aortic junctions in humans is studied by using corrosion casts of the coronary network. A model is proposed for the specification of these junctions in terms of vessel diameters and branching angles, and the model is used to produce morphological data on these junctions which hitherto have not been available. This anatomical model correlates poorly with the accepted theoretical model of arterial bifurcations in the cardiovascular system. The results suggest that the structure of the coronary-aortic junctions is very different from the structure of typical arterial bifurcations and, by implication, that the flow conditions under which they function are very different. A good understanding of these junctions is important in coronary bypass surgery, where the coronary-aortic junctions are emulated by creating a new anastomosis for the graft at the base of the ascending aorta, and in coronary artery disease, where atherosclerotic lesions occur not far from the coronary-aortic junctions.
authors.affiliation: Department of Pathology, University of Western Ontario, London, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Zamir
authors.forename: P
authors.initials: P
authors.lastname: Sinclair
mesh_terms: D001011:Aorta / Q000033:anatomy & histology; D001158:Arteries / Q000033:anatomy & histology; D003327:Coronary Disease / Q000209:etiology; D003331:Coronary Vessels / Q000033:anatomy & histology*; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular