Memory deficit in passive-avoidance learning in bulbectomized Long-Evans hooded rats.
Male and female Long-Evans hooded rats were subjected to either olfactory bulb damage or control surgery. Olfactory bulb removal resulted in increased mouse killing, increased irritability to handling, and increased open-field activity. In acquisition trials on a modified passive-avoidance apparatus, control animals habituated rapidly to the apparatus, while OB rats showed little evidence for habituation. All controls showed 24-hour retention of shock on the last acquisition trial, while OB rats showed the typical retention deficit, despite being given a behavioral alternative to withholding a response. The P-A deficit in OB rats appears to be a learning/memory deficit, not the result of heightened activity.
Thorne
B M
BM
Psychology Department, Mississippi State University, MS 39762.
Rowles
J S
JS
D000374:Aggression / Q000502:physiology; D000818:Animals; D001143:Arousal / Q000502:physiology; D001362:Avoidance Learning / Q000502:physiology*; D001835:Body Weight; D004597:Electroshock; D005260:Female; D008297:Male; D008568:Memory / Q000502:physiology*; D011939:Mental Recall / Q000502:physiology*; D009043:Motor Activity / Q000502:physiology; D009830:Olfactory Bulb / Q000502:physiology*; D009949:Orientation / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains