Primary hyperparathyroidism presenting with a maxillary tumour and hydrocephalus.
Primary hyperparathyroidism presenting with advanced bone disease is an important differential diagnosis of 'tumours' affecting the craniofacial skeleton. We describe a case of primary hyperparathyroidism presenting with a brown tumour of the maxilla causing local symptoms. Differentiation from other giant cell lesions of the maxilla is necessary. The histological and radiological features of brown tumour, non-ossifying fibroma and reparative granuloma are all similar. Differentiation relies on plasma calcium estimation and the diagnosis of hyperparathyroidism is confirmed by serum parathyroid hormone assay.
Robinson
P J
PJ
Department of Otolaryngology, University College Hospital, London.
Woodhead
P
P
D000328:Adult; D006101:Granuloma, Giant Cell / Q000209:etiology*; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology*; D006961:Hyperparathyroidism / Q000150:complications*; D008297:Male; D008443:Maxillary Sinus; D010254:Paranasal Sinus Diseases / Q000209:etiology*