Clinching the diagnosis: applications of recombinant DNA techniques.
rDNA tests are playing an increasing role in the diagnostic laboratory. These tests have a number of advantages over conventional protein or biochemical markers. Their main disadvantages are interpretation of results and technical problems. The latter will, in many cases, be resolved by availability of kits. On the other hand, interpretation can be difficult and requires experience as well as close liaison between clinicians and the laboratory.
Trent
R J
RJ
Molecular Biology Laboratory, University of Sydney.
D000328:Adult; D004247:DNA / Q000032:analysis; D015342:DNA Probes; D004274:DNA, Recombinant; D005260:Female; D005554:Forensic Medicine; D030342:Genetic Diseases, Inborn / Q000175:diagnosis*; D005819:Genetic Markers; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000175:diagnosis*; D008297:Male; D009693:Nucleic Acid Hybridization; D011110:Polymorphism, Genetic; D011933:Reagent Kits, Diagnostic; D015183:Restriction Mapping
D015342:DNA Probes; D004274:DNA, Recombinant; D005819:Genetic Markers; D011933:Reagent Kits, Diagnostic; D004247:DNA