Quantitative autofluorescence in the ovine and canine ocular fundus in ceroid-lipofuscinosis (Batten's disease).
Yellow-green autofluorescence was quantified in the fundi of sheep and dogs with ceroid-lipofuscinosis, using a modified photographic slit-lamp microscope with motorized scanning probe, a photomultiplier system and a digital radiometer. In age-matched controls, no fluorescence was detected. The technique should prove useful as a clinical aid in the early differential diagnosis of this disease and in the basic study of aging.
Armstrong
D
D
Department of Medical Technology, Kuwait University, Kuwait-Arabian Gulf.
Gum
G
G
Webb
A
A
Jolly
R
R
D000375:Aging; D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D005451:Fluorescein Angiography / Q000662:veterinary; D005654:Fundus Oculi; D009472:Neuronal Ceroid-Lipofuscinoses / Q000175:diagnosis / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000175:diagnosis*