[The frequency of chromosome aberrations in rat bone marrow cells in the late period after a single uptake of tritium].
A prolonged self-maintenance of haemopoietic tissue cells with stable chromosome rearrangements following a single intake of tritium oxide in the amount of 24 MBq/g of body weight (absorbed dose of 11 Gy) is shown. Mutant cells revealed long after the radionuclide exposure are descendants of stem-cell precursors, bearing stable chromosome aberrations during the period of formation of radiation injury after the radionuclide administration.
Muksinova
K N
KN
Nikolaevskaia
N G
NG
Uriadnitskaia
T I
TI
D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects* / Q000648:ultrastructure; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D006412:Hematopoietic Stem Cells / Q000528:radiation effects / Q000648:ultrastructure; D008297:Male; D008677:Metaphase / Q000528:radiation effects; D009154:Mutation; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014316:Tritium / Q000494:pharmacology*
D014316:Tritium
Chastota aberratsiĭ khromosom kletok kostnogo mozga krys v otdalennom periode posle odnokratnogo postupleniia tritiia.