title: G6PD deficiency and breast cancer.
abstract: A study of the relative 2dG6P utilization in mononuclear cells from a group of 150 women with breast cancer was undertaken to evaluate a possible negative correlation between G6PD deficiency and cancer, as suggested by some authors. Twenty-one women (14.00%) were heterozygotes and 2 were homozygotes (1.33%). The prevalence found was not different from that expected. It would therefore seem that the G6PD Mediterranean allele does not play a protective role against the development of breast cancer.
authors.affiliation: Clinica Pediatrica A. Filia, Università di Sassari, Italia.
authors.forename: G
authors.initials: G
authors.lastname: Forteleoni
authors.forename: L
authors.initials: L
authors.lastname: Argiolas
authors.forename: A
authors.initials: A
authors.lastname: Farris
authors.forename: A M
authors.initials: AM
authors.lastname: Ferraris
authors.forename: G F
authors.initials: GF
authors.lastname: Gaetani
authors.forename: T
authors.initials: T
authors.lastname: Meloni
mesh_terms: D000328:Adult; D000483:Alleles; D001943:Breast Neoplasms / Q000201:enzymology* / Q000209:etiology; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications*; D006801:Humans; D008875:Middle Aged
chemical_list: D005954:Glucosephosphate Dehydrogenase