[Experimental modification of the nephro- and gastroenterotoxicity of cisplatin].
The effect of complex-forming sorbent K-2-9 on cisplatin toxicity was studied experimentally. Simultaneous treatment with the preparations was shown to lower the nephro- and gastroenterotoxicity of cisplatin did not detract from the antitumor effect of cisplatin.
Kulik
G I
GI
Chekhun
V F
VF
Pel'kis
F P
FP
Boĭm
T M
TM
D000818:Animals; D002614:Chelating Agents / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use / Q000633:toxicity*; D004064:Digestive System / Q000187:drug effects* / Q000473:pathology; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D051381:Rats
D002614:Chelating Agents; D002945:Cisplatin
Mofikatsiia nefro- i gastroenterotoksichnosti tsisplatina v éksperimente.