title: [Development of laryngeal papillomatosis in children. Apropos of 17 cases].
abstract: Seventeen children (ages ranging from 2 to 11 years at the onset of the study) were followed for 24.5 +/- 15 months (3 to 47 months) for a laryngeal papillomatosis requiring tracheotomy in 14. In 8 of the children evolution was low with a decrease or disappearance of relapses. On the contrary, 9 children, i.e. more than half the cases, presented with highly crippling disease, with frequent relapses of the laryngeal papillomas, extension of the lesions to the trachea, bronchi or even lungs, and local laryngeal complications (synechiae, sub-glottic stenosis). Medical anti-proliferative treatments had no effect. These children were submitted to iterative excisions. In 4 of them tracheotomy remained necessary after 3 years of evolution and their vital prognosis might become involved, either because of local complications or due to the extension of the lesions.
authors.affiliation: Centre Thérapeutique Pédiatrique, Hôpital Bretonneau, Paris.
authors.forename: L
authors.initials: L
authors.lastname: Cathelineau
authors.forename: C
authors.initials: C
authors.lastname: Pages
authors.forename: F
authors.initials: F
authors.lastname: Aubier
authors.forename: P
authors.initials: P
authors.lastname: Guimbaud
authors.forename: P
authors.initials: P
authors.lastname: Narcy
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007822:Laryngeal Neoplasms / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D008297:Male; D010212:Papilloma / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D011184:Postoperative Period; D011379:Prognosis; D014140:Tracheotomy
vernacular_title: Evolution de la papillomatose laryngée de l'enfant. A propos de 17 cas.