title: A field outbreak in Ile-de-France sheep of a cardiotoxicosis caused by the plant Pachystigma pygmaeum (Schltr) Robyns (Rubiaceae).
abstract: A field outbreak of Pachystigma pygmaeum intoxication in sheep is described. Noteworthy clinical signs were: respiratory distress, apathy and subcutaneous oedema of mainly the head. Gross changes included cardiomegaly, centrilobular hepatic necrosis and effusion of body cavities. Microscopically myocardial fibrosis, affecting predominantly the endocardium of the apex, left free ventricular wall and interventricular septum, was most striking in the majority of animals, whilst myofibre atrophy was present in 1 sheep.
authors.affiliation: Section of Pathology, Veterinary Research Institute, Onderstepoort.
authors.forename: L
authors.initials: L
authors.lastname: Prozesky
authors.forename: N
authors.initials: N
authors.lastname: Fourie
authors.forename: J A
authors.initials: JA
authors.lastname: Neser
authors.forename: P W
authors.initials: PW
authors.lastname: Nel
mesh_terms: D000818:Animals; D005260:Female; D006333:Heart Failure / Q000473:pathology / Q000662:veterinary*; D008099:Liver / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D010939:Plant Poisoning / Q000473:pathology / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000473:pathology*; D013019:South Africa