title: [Systolic pressure--left-ventricular telesystolic volume ratio in the treatment of hypertension with a cardioselective beta-blockader without inner sympathomimetic activity].
abstract: The ratio systolic pressure--telesystolic volume (SP-TV) was determined in 39 patients with II degree hypertension by M-type echocardiography and simultaneous measurement of the arterial pressure before and at the end of the I and VI month of treatment with a cardioselective beta-blocker without a sympathicomimetic activity. The initial values of the ratio SP-TV did not differ from those of healthy persons. At the end of the first month of treatment the ratio was reliably lower (p less than 0.001) and at the end of the sixth month it increased but remained reliably lower than that of healthy persons (p less than 0.045). At the end of the sixth month the left ventricular muscular mass was reliably reduced. A large up to significant negative correlation was established between the ratio SP-TV and the left ventricular muscular mass before and after the treatment. The left ventricular pump function showed favorable dynamics.
authors.forename: V
authors.initials: V
authors.lastname: Sirakova
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002306:Cardiac Volume / Q000187:drug effects; D005260:Female; D006352:Heart Ventricles / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D008790:Metoprolol / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D008790:Metoprolol
vernacular_title: Otnoshenieto sistolno naliagane--telesistolen obem na liavata kamera pri lechenie na khipertonichnata bolest s kardioselektiven beta-bloker bez vutreshna simpatikomimetichna aktivnost.