Determination of drugs containing fluorine with ion-selective electrode. Part 1: Synthetic glucocorticosteroids.
Synthethic glucocorticosteroids (fludrocortisone acetate, fluocinolone acetate, flumethasone pivalate, triamcinolone acetonide and dexamethasone acetate) were determined on the basis of their fluoride content, when deflagrated after Schöniger, in three ways: by potentiometric titration or by direct potential measurement of ion-selective fluoride electrode or by spectrophotometry with lanthanum alizarin complexan.
Hopkała
H
H
Department of Medicinal Chemistry, Medical Academy, Lublin, Poland.
Przyborowski
L
L
D055598:Chemical Phenomena; D002621:Chemistry; D004566:Electrodes; D005938:Glucocorticoids / Q000032:analysis*; D011199:Potentiometry; D013053:Spectrophotometry
D005938:Glucocorticoids