title: [The therapeutic value of second-look laparotomy in advanced ovarian carcinoma].
abstract: 42 patients with advanced epithelial ovarian carcinoma who were clinically free of disease after completed postoperative chemotherapy were submitted to second-look laparotomy at the University clinics of Bilbao and Santander, in Northern Spain, between 1980 and 1987. Tumor was demonstrated in 22 of the cases (52.3%). This paper deals with the question of whether this knowledge and the ensuing change in therapy resulted in a longterm benefit for the patients or not. In our experience, this was not the case. All second-look-positive patients either died during the follow-up period, or showed tumor progression if they survived more than 6 months. Survival sank to 50% after only 24 months, and steadily thereafter to 0% after 78 months. The therapeutical value of second-look laparotomy is heavily questioned by these results.
authors.affiliation: Abteilung für Geburtshilfe und Frauenheilkunde, Universitätsklinik (Hospital de Cruces), Bilbao/Spanien.
authors.forename: J
authors.initials: J
authors.lastname: Schneider
authors.forename: M
authors.initials: M
authors.lastname: Martin
authors.forename: F
authors.initials: F
authors.lastname: Erasun
authors.forename: J C
authors.initials: JC
authors.lastname: Matia
authors.forename: F J
authors.initials: FJ
authors.lastname: Rodriguez-Escudero
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003536:Cystadenocarcinoma / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D004715:Endometriosis / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery*; D012086:Reoperation
vernacular_title: Zur Problematik des therapeutischen Wertes der Second-look-Laparotomie beim fortgeschrittenen Ovarialkarzinom.