[Holoprosencephaly, polydactyly, cardiopathy: new syndrome or a new case of hydrolethalus?].
We present a foetus, 46,XY, with holoprosencephaly, hydrocephaly, unilateral lower limb post axial polydactyly, clubhands, auricular septal defect, umbilical cord hernia. The differential diagnosis of the condition is discussed: especially the hydrolethalus syndrome, and the Young and Madders' syndrome reported in 1987.
André
S A
SA
Service de Génétique, Hôtel-Dieu, Lyon.
Cordier
M P
MP
Beaufrère
A M
AM
Guillaud
M
M
Robert
J M
JM
D000015:Abnormalities, Multiple / Q000473:pathology*; D005385:Fingers / Q000002:abnormalities; D006330:Heart Defects, Congenital / Q000473:pathology; D006801:Humans; D006849:Hydrocephalus / Q000473:pathology; D013577:Syndrome
Holoprosencéphalie, polydactylie, cardiopathie: nouveau syndrome ou un nouveau cas d'hydrolethalus?