title: Relation of ethanol self-administration to feeding and drinking in a nonrestricted access situation in rats initiated to self-administer ethanol using the sucrose-fading technique.
abstract: Free-feeding male Long-Evans rats (N = 8) were initiated to self-administer 10% ethanol using a sucrose-fading procedure. Following initiation, they were placed into chambers which allowed for the continuous monitoring of feeding, water drinking and ethanol self-administration. All rats continued to daily self-administer ethanol in the continuous access situation. Ethanol drinking at certain times during the day appeared to be related to feeding bouts (prandial drinking). However, at other times, nonprandial ethanol self-administration occurred. These nonprandial ethanol drinking episodes, while not at levels of excessive ethanol intakes, were at levels well above water intake when water was substituted for ethanol. These findings suggest that ethanol intake in continuous access conditions is not solely a function of feeding behavior and that following initiation, ethanol-seeking behavior was maintained in a continuous access situation.
authors.affiliation: Alcohol and Drug Abuse Institute, University of Washington, Seattle 98195.
authors.forename: H H
authors.initials: HH
authors.lastname: Samson
authors.forename: G A
authors.initials: GA
authors.lastname: Tolliver
authors.forename: A O
authors.initials: AO
authors.lastname: Pfeffer
authors.forename: K
authors.initials: K
authors.lastname: Sadeghi
authors.forename: M
authors.initials: M
authors.lastname: Haraguchi
mesh_terms: D000428:Alcohol Drinking; D000818:Animals; D004326:Drinking; D004435:Eating; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013395:Sucrose / Q000008:administration & dosage
chemical_list: D013395:Sucrose