title: Liquid chromatographic and mass spectral analysis of N-substituted analogues of 3,4-methylenedioxyamphetamine.
abstract: The C1 to C3 N-alkyl, N,N-dimethyl, and N-hydroxy analogues of 3,4-methylenedioxyamphetamine (MDA) are identified by high performance liquid chromatographic (HPLC) and spectrometric techniques. The compounds are separated using reversed-phase procedures on C18 stationary phase with an acidic (pH 3) aqueous methanol mobile phase. The mass spectra of the compounds are distinctive and reference spectra are provided. The N-hydroxy derivative is unstable at high temperatures and decomposes to MDA and the oxime of 3,4-methylenedioxyphenyl-2-propanone.
authors.affiliation: Alabama Department of Forensic Sciences, Auburn 36830.
authors.forename: F T
authors.initials: FT
authors.lastname: Noggle
authors.forename: C R
authors.initials: CR
authors.lastname: Clark
authors.forename: A K
authors.initials: AK
authors.lastname: Valaer
authors.forename: J
authors.initials: J
authors.lastname: DeRuiter
mesh_terms: D015104:3,4-Methylenedioxyamphetamine / Q000031:analogs & derivatives / Q000032:analysis*; D000662:Amphetamines / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D007202:Indicators and Reagents; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000662:Amphetamines; D007202:Indicators and Reagents; D015104:3,4-Methylenedioxyamphetamine