title: [Function of the sympathetico-adrenal system and the acid-base equilibrium in newborn infants with a hypoxic lesion of the central nervous system].
abstract: The function of the sympathetic-adrenal system was studied by measuring umbilical cord blood catecholamines in 31 full-term newborns with perinatal asphyxia and evidence of hypoxic-ischemic encephalopathy (HIE) and in 20 normal newborns. The results indicate that the full-term newborn responds to asphyxia with graded catecholamine release. The epinephrine concentration in newborns with moderate HIE is lower than in newborns with mild HIE, which may reflect decreased sympathetic-adrenal function due to prolonged asphyxia. Acid-base values in capillary blood and lumbar cerebrospinal fluid were determined in the babies with HIE, with the findings pointing to metabolic acidosis which was more expressed in cerebrospinal fluid.
authors.forename: M Ia
authors.initials: MIa
authors.lastname: Mialksoo
authors.forename: T A
authors.initials: TA
authors.lastname: Tal'vik
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Paiu
authors.forename: A E
authors.initials: AE
authors.lastname: Kaasik
authors.forename: A G
authors.initials: AG
authors.lastname: Sëzt
mesh_terms: D000136:Acid-Base Equilibrium; D000311:Adrenal Glands / Q000503:physiopathology*; D001238:Asphyxia Neonatorum / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D002493:Central Nervous System Diseases / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D004837:Epinephrine / Q000097:blood; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D009638:Norepinephrine / Q000097:blood; D013564:Sympathetic Nervous System / Q000503:physiopathology*
chemical_list: D009638:Norepinephrine; D004837:Epinephrine
vernacular_title: Sostoianie simpatiko-adrenalovoĭ sistemy i kislotno-shchelochnogo ravnovesiia u novorozhdennykh s gipoksicheskim porazheniem tsentral'nĭ nervnoĭ sistemy.