title: Percutaneous biopsy of the proximal humeral growth plate in dogs.
abstract: A percutaneous biopsy technique for the study of endochondral bone formation in the dog was developed. With the dogs under general anesthesia or sedated with a combination of a tranquilizer and a local anesthetic, biopsy specimens were obtained from the proximal growth plate of the humerus with the use of a Jamshidi bone biopsy needle. Biopsy specimens were structurally intact, and contained epiphysis, growth plate, and metaphysis. The procedure proved to be a simple, safe technique, which caused minimal discomfort for the patient and did not affect the growth of the proximal end of the humerus, even after multiple biopsies.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
authors.forename: G J
authors.initials: GJ
authors.lastname: Breur
authors.forename: R F
authors.initials: RF
authors.lastname: Slocombe
authors.forename: T D
authors.initials: TD
authors.lastname: Braden
mesh_terms: D000818:Animals; D001707:Biopsy, Needle / Q000379:methods / Q000662:veterinary; D001848:Bone Diseases, Developmental / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs / Q000033:anatomy & histology*; D005260:Female; D006132:Growth Plate / Q000033:anatomy & histology / Q000473:pathology*; D006811:Humerus / Q000033:anatomy & histology / Q000473:pathology*; D008297:Male