Serum testosterone level in the peripheral vein and the perigastric draining vein of patients with gastric carcinoma.
The serum testosterone level (STL) was determined in 181 patients with gastric carcinoma, 128 male and 53 female, and in 98 patients with benign diseases, 67 male and 31 female. As in our previous report, the preoperative STL of the cancer group was significantly lower than that of the control group, in both male and female patients (P less than 0.001). In the present study, the STL of the perigastric vein draining the stomach was determined and compared with the STL of the blood obtained at the same time from the peripheral vein during the operation. It was found that, in the male patients, the STL of the blood obtained from the perigastric vein draining a stomach with carcinoma was significantly lower than that of the peripheral vein in the same patient (P less than 0.001); however, there was no difference between these STL in the control group. On the contrary, in the female patients during operation, no such phenomenon was confirmed. Analysis classifying the patients by histological type revealed almost the same results for all patients as those shown for the cancer group, i.e. there was a proven significant difference in male patients and no significant difference in female patients. It was therefore considered that the mechanism of decrease in preoperative peripheral STL was not always the same in male patients as in female patients, although the STL decrease was observed to be similar in both sexes before surgery.
Inutsuka
S
S
Second Department of Surgery, School of Medicine, Fukuoka University.
Kumashiro
R
R
Maekawa
T
T
Hirabayashi
M
M
Naitoh
H
H
Kamachi
H
H
D000230:Adenocarcinoma / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D012737:Sex Factors; D013274:Stomach Neoplasms / Q000097:blood* / Q000098:blood supply / Q000473:pathology; D013739:Testosterone / Q000097:blood*; D014680:Veins
D013739:Testosterone