title: Uncommon histological variants of clear cell carcinoma of the ovary. Report of two cases with immunohistochemical and ploidy studies.
abstract: Two cases of clear cell carcinoma of the ovary with uncommon histological features are here presented. The former showed considerable formation of giant, hCG-negative tumour cells. In the latter the clear cell pattern was admixed with smaller elements that resembled steroid-hormone secreting cells. However, these cells revealed negative immunostaining for testosterone and a higher degree of DNA content abnormalities than the clear cell component.
authors.affiliation: Department of Pathology, City Hospital, Alessandria, Italy.
authors.forename: P G
authors.initials: PG
authors.lastname: Betta
authors.forename: F
authors.initials: F
authors.lastname: Robutti
authors.forename: G
authors.initials: G
authors.lastname: Spinoglio
authors.forename: G
authors.initials: G
authors.lastname: Bottero
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology*; D004247:DNA / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology*; D011379:Prognosis
chemical_list: D004247:DNA