Behçet's disease and major histocompatibility complex class II antigens in Tunisians.
Forty-two Tunisian patients suffering from Behçet's disease (23 with uveitis) were typed for HLA-DR and DQ antigens. There was a significant excess of HLA-DQw3 (p less than 0.01) but also an important deficiency of HLA-DRw6 and DQw1 (p less than 0.01). A substantial increase of HLA-DR2 (p less than 0.01) for those with uveitis, and of HLA-DR4, DR7, for the others has been recorded (p less than 0.01).
Hamza
M
M
Departement de Medecine, Secteur Rhumatologie Faculte de Medecine de Tunis, Hopital La Rabta, Tunisia.
Ayed
K
K
Hamzaoui
K
K
Bardi
R
R
D000328:Adult; D001528:Behcet Syndrome / Q000235:genetics* / Q000276:immunology; D005006:Ethnicity; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D006681:HLA-D Antigens / Q000235:genetics*; D006683:HLA-DQ Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D014416:Tunisia
D005819:Genetic Markers; D006681:HLA-D Antigens; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens