Uncommon histological variants of clear cell carcinoma of the ovary. Report of two cases with immunohistochemical and ploidy studies.
Two cases of clear cell carcinoma of the ovary with uncommon histological features are here presented. The former showed considerable formation of giant, hCG-negative tumour cells. In the latter the clear cell pattern was admixed with smaller elements that resembled steroid-hormone secreting cells. However, these cells revealed negative immunostaining for testosterone and a higher degree of DNA content abnormalities than the clear cell component.
Betta
P G
PG
Department of Pathology, City Hospital, Alessandria, Italy.
Robutti
F
F
Spinoglio
G
G
Bottero
G
G
D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology*; D004247:DNA / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology*; D011379:Prognosis
D004247:DNA