title: Spontaneous remission of acromegaly after pituitary apoplexy following head trauma.
abstract: A 34-year-old man with acromegaly was observed, and the clinical course and various endocrinological deficiencies occurring before, during and after the development of pituitary apoplexy were evaluated. Following the attack, the patient experienced acute reductions in growth hormone (GH) and other pituitary hormones, adrenohypophyseal insufficiency and transient diabetes insipidus which appeared subsequent to glucocorticoid therapy. The level of growth hormone in serum and cerebrospinal fluid (CSF) was measured synchronously, and the respective regressions of GH levels in serum and CSF were observed. The results demonstrated the utility of measuring hormonal levels in CSF in the clinical evaluation of pituitary apoplexy in a patient with a functioning pituitary tumor.
authors.affiliation: Third Department of Internal Medicine, Hirosaki University School of Medicine, Aomori-ken, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Tamasawa
authors.forename: K
authors.initials: K
authors.lastname: Kurahashi
authors.forename: T
authors.initials: T
authors.lastname: Baba
authors.forename: R
authors.initials: R
authors.lastname: Hishita
authors.forename: S
authors.initials: S
authors.lastname: Murabayashi
authors.forename: H
authors.initials: H
authors.lastname: Kashiwamura
authors.forename: K
authors.initials: K
authors.lastname: Takebe
mesh_terms: D000172:Acromegaly / Q000150:complications / Q000503:physiopathology*; D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use; D006259:Craniocerebral Trauma / Q000150:complications*; D003919:Diabetes Insipidus / Q000209:etiology / Q000503:physiopathology; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008297:Male; D010899:Pituitary Apoplexy / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D010902:Pituitary Gland / Q000503:physiopathology; D012075:Remission, Spontaneous
chemical_list: D001971:Bromocriptine; D013006:Growth Hormone; D006854:Hydrocortisone