Thermal changes produced by norepinephrine application in the preoptic area of monkeys.
The effect of injection of norepinephrine in the anterior regions of hypothalamus on rectal temperature, skin temperature, heart rate and respiratory rate in rhesus monkeys was studied. The injection of 2 micrograms of norepinephrine in the preoptic area produced a fall in body temperature without any accompanying change in skin temperature, heart rate and respiratory rate. The findings suggest that the suppression of heat production may be responsible for the norepinephrine induced hypothermia in monkeys.
Mallick
H N
HN
Department of Physiology, All India Institute of Medical Sciences, New Delhi.
Kumar
V M
VM
Singh
B
B
D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D001833:Body Temperature Regulation / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D007035:Hypothermia / Q000139:chemically induced* / Q000503:physiopathology; D008253:Macaca mulatta; D008297:Male; D009638:Norepinephrine / Q000008:administration & dosage / Q000494:pharmacology*; D011301:Preoptic Area / Q000187:drug effects* / Q000503:physiopathology; D012119:Respiration / Q000187:drug effects; D012881:Skin Temperature / Q000187:drug effects
D009638:Norepinephrine