Prevalence of serum antibodies to toxic-shock-syndrome-toxin-1 and to staphylococcal enterotoxins A, B and C in West-Germany.
Sera of 152 healthy blood donors and 43 infants 9 to 12 months of age were tested for serum antibodies to TSST-1 and staphylococcal enterotoxins A, B and C by a microtiter ELISA assay. Only 50% of the adult population had detectable antibody-titers to enterotoxin A, whereas 80% to enterotoxin C and 90% to enterotoxin B and TSST-1, which is very similar to the prevalence of TSST-1 antibodies among USA-residents. The "protective" titer of TSST-1-antibodies can be estimated to be 1:100 in the test system used by comparison with anti-TSST-1-titers in five acute phase sera from confirmed menstrual TSS cases.
Schröder
E
E
Hygiene-Institut der Universität zu Köln.
Kunstmann
G
G
Hasbach
H
H
Pulverer
G
G
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D001427:Bacterial Toxins; D001782:Blood Donors; D004768:Enterotoxins / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005860:Germany, West; D006801:Humans; D007223:Infant; D008875:Middle Aged; D012772:Shock, Septic / Q000453:epidemiology*; D013211:Staphylococcus aureus / Q000276:immunology*; D018089:Superantigens
D000907:Antibodies, Bacterial; D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; C026066:enterotoxin A, Staphylococcal; C031818:enterotoxin B, staphylococcal; C034959:enterotoxin C, staphylococcal