Pigmented nail streaks may indicate Laugier-Hunziker syndrome.
Laugier-Hunziker syndrome is a rare, benign pigmentation disorder previously described only once in the United States. The syndrome is acquired in early or mid-adult life and is characterized by multiple longitudinal hyperpigmented bands on the nails and pigmented macules of the lips and buccal mucosa. Peutz-Jeghers syndrome and Addison's disease can present with pigment abnormalities similar to those characteristic of Laugier-Hunziker syndrome.
Sterling
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Winthrop-University Hospital, Mineola, New York.
Libow
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Grossman
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D000368:Aged; D005260:Female; D006801:Humans; D009061:Mouth Mucosa / Q000473:pathology; D009262:Nails / Q000473:pathology*; D010859:Pigmentation Disorders / Q000175:diagnosis / Q000473:pathology*; D013577:Syndrome