title: A field evaluation of benzimidazole and nonbenzimidazole drugs in a herd of dairy goats.
abstract: A study was conducted to investigate the efficacy of six anthelmintics in a herd of dairy goats. Pretreatment larval cultures indicated that the goats were infected with Haemonchus contortus and Trichostrongylus colubriformis. Three separate treatment regimens were administered. In each trial, mature nonlactating goats were allocated into two treatment groups and a control group. Treatment groups received thiabendazole (TBZ) or levamisole (LEV), mebendazole (MBZ) or fenbendazole (FBZ), and morantel tartrate (MOR) or ivermectin (IVR). LEV, MOR, and IVR reduced fecal strongyle egg counts by 99% to 100% of pretreatment values. The benzimidazole (BZD) drugs changed pretreatment fecal egg counts by +2% to -32%. Results of posttreatment larval culture demonstrated the presence of H contortus larvae following the administration of BZD drugs.
authors.affiliation: Department of Food Animal and Equine Medicine, North Carolina State University, School of Veterinary Medicine, Raleigh 27606.
authors.forename: C
authors.initials: C
authors.lastname: Uhlinger
authors.forename: J
authors.initials: J
authors.lastname: Fetrow
authors.forename: C
authors.initials: C
authors.lastname: Johnstone
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D005260:Female; D005273:Fenbendazole / Q000627:therapeutic use; D006041:Goats / Q000469:parasitology*; D006188:Haemonchiasis / Q000188:drug therapy / Q000662:veterinary*; D006189:Haemonchus / Q000187:drug effects; D007559:Ivermectin / Q000627:therapeutic use; D007978:Levamisole / Q000627:therapeutic use; D008463:Mebendazole / Q000627:therapeutic use; D009015:Morantel / Q000627:therapeutic use; D010270:Parasite Egg Count / Q000662:veterinary; D013827:Thiabendazole / Q000627:therapeutic use; D014252:Trichostrongyloidiasis / Q000662:veterinary*; D014253:Trichostrongylosis / Q000188:drug therapy / Q000662:veterinary*; D014254:Trichostrongylus / Q000187:drug effects
chemical_list: D000871:Anthelmintics; D001562:Benzimidazoles; D007978:Levamisole; D005273:Fenbendazole; D007559:Ivermectin; D009015:Morantel; D008463:Mebendazole; D013827:Thiabendazole