[Su-polysaccharide skin test and immunotherapy with OK-432 in postoperative gastric cancer--the effect of a splenectomy].
A SU-polysaccharide skin test (SU-PS test) has been employed and studied as a parameter for monitoring the immunological status of OK-432 treated patients who had undergone a curative gastrectomy for a gastric cancer in stages II and III. The median diameter of the erythema (SU-PS value) was found to have no relation to the number of lymphocytes and the serum protein level and was depressed by combined chemotherapy. The SU-PS value was significantly higher in patients not given a splenectomy than in patients who had undergone a patients splenectomy. The spleen is considered the essential organ to focus on in OK-432 immunotherapy.
Saito
H
H
Dept. of Surgery, Koseiren Takaoka Hospital.
Kikkawa
H
H
Bando
H
H
Sakatoku
M
M
Hirano
M
M
Tatsuzawa
T
T
D000368:Aged; D001688:Biological Products / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007167:Immunotherapy; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000627:therapeutic use*; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D011184:Postoperative Period; D012882:Skin Tests; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000276:immunology* / Q000601:surgery / Q000628:therapy; D013291:Streptococcus / Q000276:immunology*
D001688:Biological Products; D011135:Polysaccharides, Bacterial; D010844:Picibanil