title: Rett syndrome: case reports and management strategies.
abstract: Rett Syndrome (RS) is a mental retardation syndrome occurring in females consisting of normal pre-, peri-, and neonatal growth and development, followed by rapid regression after 3 but before 30 months, an arrest of the regression and a developmental plateau. The regression results in autistic behavior, with loss of production and comprehension of language, seizures, hyperventilation, characteristic hand-wringing, and ataxic gait. Four case histories of RS from the authors' practice are presented. Management strategies are presented and needed research is suggested.
authors.affiliation: Child Evaluation and Treatment Program, Medical Center Rehabilitation Hospital, Grand Forks, ND 58201.
authors.forename: L
authors.initials: L
authors.lastname: Burd
authors.forename: G
authors.initials: G
authors.lastname: Gascon
authors.forename: J
authors.initials: J
authors.lastname: Kerbeshian
mesh_terms: D000293:Adolescent; D001927:Brain Diseases / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology*