[The effect of side radicals on the peptide structure. Surface of potential energy of model alanine and phenylalanine dipeptides].
The problem of stabilization of different dipeptide conformations is discussed within the fragment-fragment interactions method. It is shown, that the introduction of a CH3-group in glycine is a weak perturbation and for Ala-dipeptide the preferential structure remains C7 (like for glycine). On the contrary the introduction of a C6H5CH2-group in glycine is a strong perturbation and for Phe-dipeptide C5 becomes the preferential structure.
Basharov
M A
MA
Vol'kenshteĭn
M V
MV
Golovanov
I B
IB
D000409:Alanine; D055598:Chemical Phenomena; D002621:Chemistry; D004151:Dipeptides; D008958:Models, Molecular; D010649:Phenylalanine; D011487:Protein Conformation
D004151:Dipeptides; D010649:Phenylalanine; D000409:Alanine
Vliianie bokovykh radikalov na strukturu peptidov. Poverkhnosti potentsial'noĭ énergii model'nykh dipeptidov alanina i fenilalanina.