title: Parkinsonian syndrome after cardiac arrest: radiological and neurochemical changes.
abstract: Following a cardiac arrest, a 21-year-old man developed a Parkinson syndrome. This was due to, as shown by brain computerized tomography (CT) and magnetic resonance imaging (MRI), symmetrical infarctions of the basal ganglia, especially the globi pallidi. The levels of homovanillic acid (HVA) in the CSF were lower than normal, pointing to a possible alteration of the central dopaminergic activity. An alteration of the opioid system may also be supposed because of the extremely high levels of methionine-enkephalin (Met-Enk).
authors.affiliation: Department of Neurology, Algemeen Ziekenhuis Middelheim, Antwerp, Belgium.
authors.forename: W
authors.initials: W
authors.lastname: Verslegers
authors.forename: R
authors.initials: R
authors.lastname: Crols
authors.forename: M
authors.initials: M
authors.lastname: van den Kerchove
authors.forename: W
authors.initials: W
authors.lastname: de Potter
authors.forename: B
authors.initials: B
authors.lastname: Appel
authors.forename: A
authors.initials: A
authors.lastname: Lowenthal
mesh_terms: D000328:Adult; D001921:Brain / Q000187:drug effects; D004298:Dopamine / Q000378:metabolism*; D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D013287:Illicit Drugs; D008279:Magnetic Resonance Imaging; D008297:Male; D010302:Parkinson Disease, Secondary / Q000139:chemically induced*; D019966:Substance-Related Disorders / Q000150:complications*; D014057:Tomography, X-Ray Computed
chemical_list: D013287:Illicit Drugs; D004298:Dopamine