Pathophysiological sequelae of hepatic artery ligation: an experimental study.
The effects of ligation of the proper hepatic artery were studied in 40 rats. The serum transaminase and bilirubin levels were elevated significantly at 24 h following surgery but had returned to normal by the 7th postoperative day. The serum albumin level was significantly reduced at 24 h and remained low for a further 2 weeks. There was no histological abnormality in the liver following hepatic artery ligation. It would appear that there is an early return to normal function following hepatic artery ligation.
O'Donohoe
M K
MK
University Department of Surgery, University College, Dublin, Ireland.
Blake
A
A
Waldron
R P
RP
Dervan
P
P
Fitzpatrick
J M
JM
D000818:Animals; D001663:Bilirubin / Q000097:blood; D006499:Hepatic Artery / Q000502:physiology / Q000601:surgery*; D008026:Ligation; D008102:Liver Circulation; D051381:Rats; D011919:Rats, Inbred Strains; D012709:Serum Albumin / Q000032:analysis; D000637:Transaminases / Q000097:blood
D012709:Serum Albumin; D000637:Transaminases; D001663:Bilirubin