Serum concentration of protein CA-125 in women with pelvic inflammatory disease.
The concentration of the protein CA-125 in serum was determined in women with a normal pelvis visualized at laparoscopy (control group, n = 15) and compared with serum levels of this protein in women with pelvic inflammatory disease (PID) (n = 14). Mean serum concentrations of CA-125 were similar in the two groups: 17.4 +/- 2.3 (SE) units/ml for the control group vs. 17.0 +/- 4.3 units/ml for those with PID (P greater than 0.05). In addition, women with chlamydial cervicitis, histologically confirmed endometritis, and laparoscopically documented salpingitis had CA-125 levels that were not significantly different from those of controls. We conclude that serum levels of CA-125 will not be useful in the diagnosis of PID.
Brumsted
J R
JR
Department of Obstetrics and Gynecology, College of Medicine, University of Vermont, Burlington 05405.
Mead
P B
PB
Gibson
M
M
D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D002690:Chlamydia Infections / Q000097:blood; D002692:Chlamydia trachomatis; D005260:Female; D006069:Gonorrhea / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000097:blood; D000292:Pelvic Inflammatory Disease / Q000097:blood* / Q000175:diagnosis
D015295:Antigens, Tumor-Associated, Carbohydrate