[Age-related and organ-tissue characteristics of the function of the antioxidant system in white rats].
Various components of antioxidant system (concentration of the reduced and oxidated forms of non-protein thiol compounds and ascorbic acid, the activity of glucose-6-phosphate dehydrogenase, glutathione reductase, catalase, superoxide dismutase) have been investigated in the blood, brain and liver of growing albino rats. It was found that the specific condition of this system depends on the age of animals and on the source of the system. Disorganization of the antioxidant system in senile animals was noted which results from intensification of free radical oxidation.
Sokolovskiĭ
V V
VV
Makarov
V G
VG
Timofeeva
V M
VM
D000375:Aging / Q000378:metabolism*; D000818:Animals; D000975:Antioxidants; D001205:Ascorbic Acid / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002374:Catalase / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D010084:Oxidation-Reduction; D051381:Rats; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism
D000975:Antioxidants; D013438:Sulfhydryl Compounds; D005954:Glucosephosphate Dehydrogenase; D002374:Catalase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase; D001205:Ascorbic Acid
Vozrastnye i organotkanevye osobennosti sostoianiia antioksidantnoĭ sistemy belykh krys.