[Age-related peculiarities of adrenergic regulation of the contractility and pump function of the heart].
The pharmacodynamics of adrenaline were investigated with respect to the adrenergic regulation of the contractility, of the pumping function and of the systolic function of the heart, aiming at the examination of age particularities. The results show that the positively effect of adrenaline becomes less with increasing age. The arrhythmogenic effect of the preparation is described, just as its effect on blood pressure regulation. The results are discussed in detail.
Korkusko
O V
OV
Institut für Gerontologie, Akademie der Medizinischen Wissenschaften der UdSSR, Kiev.
Moroz
G Z
GZ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D002302:Cardiac Output; D004837:Epinephrine / Q000502:physiology*; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction; D009206:Myocardium / Q000378:metabolism; D010101:Oxygen Consumption
D004837:Epinephrine
Alternsbesonderheiten der adrenergen Regulation der Kontraktionsfähigkeit und der Pumpfunktion des Herzens.