title: Computed tomography in cases of multiple sclerosis: problems of differential diagnosis in cases with atypical findings.
abstract: The value of computed tomography in the diagnosis of multiple sclerosis is undisputed. The examination is usually carried out as a routine part of the examination program. We report on the CT results of 112 patients with confirmed or suspected MS. Seventy-three patients were examined without, 39 with intravenous administration of a contrast medium. In 41% of the patients, isolated or multiple hypodense foci were found as a manifestation of a multilocular demyelinization process. In 17.8%, only cerebro-atrophic changes were encountered. In 30.3% of the cases the CT showed normal results. In the group of patients examined with a contrast medium, a pathological contrast medium concentration was found in 30.7%. The differential diagnostic demarcation against other diseases of the CNS with similar CT findings and problems of differential diagnosis with MRI are discussed.
authors.affiliation: Department of Neurosurgery, University Hospital, Freiburg i.B., West Germany.
authors.forename: M
authors.initials: M
authors.lastname: Mohadjer
authors.forename: J
authors.initials: J
authors.lastname: Kohler
authors.forename: E
authors.initials: E
authors.lastname: Milios
authors.forename: F
authors.initials: F
authors.lastname: Mundinger
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed