Colocalization of [3H]muscimol uptake and choline acetyltransferase immunoreactivity in amacrine cells of the cat retina.
High affinity uptake of [3H]muscimol, a gamma-aminobutyric acid (GABA) analogue, followed by autoradiography, labelled practically all amacrine cells which expressed GABA-like immunoreactivity. Hence it is a good marker for putative GABAergic amacrine cells. All amacrine cells, which were stained with antibodies against choline acetyltransferase, a marker for cholinergic neurones, also accumulated [3H]muscimol. This makes it likely that cholinergic amacrine cells of the cat retina are a subpopulation of putative GABAergic amacrine cells.
Chun
M H
MH
Neuroanatomische Abteilung, Max-Planck-Institut für Hirnforschung, Frankfurt, F.R.G.
Wässle
H
H
Brecha
N
N
D000818:Animals; D001345:Autoradiography; D002415:Cats / Q000276:immunology / Q000378:metabolism*; D002795:Choline O-Acetyltransferase / Q000276:immunology*; D007150:Immunohistochemistry; D009118:Muscimol / Q000378:metabolism*; D012160:Retina / Q000166:cytology / Q000276:immunology / Q000378:metabolism*; D014316:Tritium; D005680:gamma-Aminobutyric Acid / Q000276:immunology
D014316:Tritium; D009118:Muscimol; D005680:gamma-Aminobutyric Acid; D002795:Choline O-Acetyltransferase