[Mercury absorption during the use of Grob crusting in the treatment of burns--an experimental animal study].
The absorption of mercury was investigated after three phase crusting by Grob on a second-degree scald burn of 10 to 15% of the body surface in rats. Mercury was provable histologically in kidney and liver already after 3 days. A clear cumulation was shown especially in kidney and liver in the further course. The abundant renal tubuli cytoclasis are to be seen in connection with mercury absorption and storage. Further depositions were provable in the subcutaneous fibroblasts of the thermically damaged skin as well as in the spleen and rarely in the brain. The investigations demonstrate that there occurs a mercury absorption. Against the employment of the formation of crust by Grob must be warned specially in burns of large planes.
Schenke
H
H
Chirurgischen Klinik, Friedrich-Schiller-Universität Jena.
Adam
G
G
D000042:Absorption; D000818:Animals; D001921:Brain / Q000378:metabolism; D002056:Burns / Q000378:metabolism / Q000628:therapy*; D005347:Fibroblasts / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008628:Mercury / Q000493:pharmacokinetics*; D051381:Rats; D012869:Skin Absorption; D013154:Spleen / Q000378:metabolism; D014018:Tissue Distribution
D008628:Mercury
Die Quecksilberresorption bei Anwendung der Grobschen Verschorfung in der Verbrennungsbehandlung--eine tierexperimentelle Studie.