Treatment of heart failure following chronic cor pulmonale with ibopamine.
A group of 36 patients with cor pulmonale chronicum were treated for 12 months with ibopamine, a dopamine-related drug, orally active, suitable for the long-term therapy of congestive heart failure. In heart failure due to chronic pulmonary disease other drugs such as digitalis are hardly effective. The results obtained indicate that ibopamine, given alone or associated to other drugs, is clinically efficient in the treatment of cor pulmonale chronicum while very few side effects definitely related to ibopamine were reported. In particular no increase in arrhythmias or significant augmentation of anginal episodes was noted.
Sabino
F
F
Medical Department, Zambon Group, Milan, Italy.
Bianco
L
L
Cantoni
V
V
Ghirardi
P
P
Marchetti
G V
GV
Cicchetti
V
V
D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D003846:Deoxyepinephrine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004232:Diuretics / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004298:Dopamine / Q000031:analogs & derivatives*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011660:Pulmonary Heart Disease / Q000150:complications* / Q000188:drug therapy
D004232:Diuretics; C023487:ibopamine; D003846:Deoxyepinephrine; D004298:Dopamine