title: Successful long term treatment of a dog with psychomotor seizures using carbamazepine.
abstract: Psychomotor seizures (temporal lobe epilepsy) were diagnosed in a dog based on history, clinical findings and electroencephalography. Long-term seizure control was achieved with carbamazepine, despite serum drug concentrations which were low to unmeasurable. It is suggested that serum levels of carbamazepine are not a useful guide to clinical efficacy in the dog, that an unmeasured metabolite of carbamazepine may account for the anti-convulsant activity and that carbamazepine may be potentially useful in treating certain canine seizure disorders.
authors.affiliation: Department of Veterinary Anatomy, University of Sydney, New South Wales.
authors.forename: C T
authors.initials: CT
authors.lastname: Holland
mesh_terms: D000818:Animals; D004049:Diethylcarbamazine / Q000097:blood / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004569:Electroencephalography / Q000662:veterinary; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy / Q000662:veterinary*; D005260:Female
chemical_list: D004049:Diethylcarbamazine