Plasma lipoproteins in neonatal, preruminant, and weaned calf.
This study compared plasma lipoprotein fraction profiles and lipid composition in the calf at 3 d, 3 wk, and 12 wk (weaned). For all ages the major plasma lipoprotein fraction was high density lipoproteins (52 to 73%), followed by very high density lipoproteins (10 to 22%), low density lipoproteins (13 to 18%), and chylomicrons plus very low density lipoproteins (5 to 9%). Most plasma lipid was cholesterol esters (41 to 49%) and phosphatidylcholine (21 to 29%). Most cholesterol esters (66 to 81%) and phosphatidylcholine (68 to 80%) were in high density lipoproteins; free fatty acids (83 to 96%) and lysophosphatidylcholine (75 to 85%) in very high density lipoproteins; and triglycerides (93 to 98%) in the remaining lipoprotein fractions. Of the three ages studied, 3-d-old calves had comparatively low plasma total lipids, high density lipoproteins, cholesterol esters, phosphatidylcholine, and linoleic acid in all lipid classes; they had relatively high plasma very high density lipoproteins, triglycerides, free fatty acids, phosphatidylethanolamine, and 20:3 n-9 fatty acid (indicative of essential fatty acids deficiency). Lipoprotein classes and lipid composition were similar at wk 3 and 12. Comparison of fatty acid profiles for phosphatidylcholine with those for lysophosphatidylcholine and cholesterol esters indicated plasma lecithin-cholesterol acyltransferase was active in calves at all three ages studied.
Jenkins
K J
KJ
Animal Research Centre, Agriculture Canada, Ottawa, Ontario.
Griffith
G
G
Kramer
J K
JK
D000375:Aging / Q000097:blood*; D000818:Animals; D000831:Animals, Newborn / Q000097:blood*; D002417:Cattle / Q000097:blood*; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000032:analysis / Q000097:blood*; D014280:Triglycerides / Q000032:analysis; D014886:Weaning
D005227:Fatty Acids; D008055:Lipids; D008074:Lipoproteins; D014280:Triglycerides