The effect of donor age on the packing susceptibility of erythrocytes.
The study of 411 healthy persons indicates that erythrocyte susceptibility to centrifugal packing at 200 g increases with age, evidencing an age-related decrease in red cell deformability. Positive correlations between donor age and blood plasma fibrinogen concentration and erythrocyte sedimentation rate were confirmed. The impairment of red cell deformability may affect the circulatory efficiency in the aged.
Judkiewicz
L
L
Institute of Pathology, Medical Academy of Lodz, Poland.
Ciszewski
R
R
Bartosz
G
G
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001782:Blood Donors; D001799:Blood Sedimentation; D002498:Centrifugation; D004907:Erythrocyte Deformability; D005340:Fibrinogen / Q000097:blood*; D006801:Humans; D008875:Middle Aged
D005340:Fibrinogen