IgA nephropathy and polycystic kidney disease.
We report a patient with polycystic kidney disease, advanced renal failure, and nephrotic-range proteinuria. Kidney biopsy revealed IgA nephropathy with lesions of focal and segmental glomerular sclerosis. This association had not been previously described and is probably coincidental. This case supports the assumption that the nephrotic-range proteinuria observed in some polycystic patients could be the consequence of another superimposed glomerular disease. This glomerulopathy can worsen the course of azotemia in these patients.
Panisello
J M
JM
Section of Nephrology, Hospital Juan XXIII, Tarragona, Spain.
Martinez-Vea
A
A
Garcia
C
C
Carrera
M
M
Oliver
J A
JA
Richart
C
C
D000368:Aged; D005922:Glomerulonephritis, IGA / Q000150:complications*; D006801:Humans; D008297:Male; D007690:Polycystic Kidney Diseases / Q000150:complications*; D011507:Proteinuria / Q000209:etiology