title: [Homeostatic reactions of the blood of experimental rats after "Kosmos-1667" flight].
abstract: Biochemical analysis of blood of rats sacrificed 4 to 8 hours after Cosmos-1667 flight revealed a significant increase of corticosterone, decrease of 11-dehydroxycortisol, testosterone, total and bound thyroxine, and increase of glucose, phosphate, creatinine, alanine aminotransferase and total antioxidative activity. Changes in hormonal concentrations, glucose content and stimulation of antioxidant defense system were associated with a moderate gravitational stress. Increases in the creatinine and inorganic phosphate concentrations can be viewed as specific effects of microgravity related to musculo-skeletal or fluid-electrolyte changes.
authors.forename: I A
authors.initials: IA
authors.lastname: Popova
authors.forename: B V
authors.initials: BV
authors.lastname: Afonin
authors.forename: E G
authors.initials: EG
authors.lastname: Vetrova
authors.forename: T E
authors.initials: TE
authors.lastname: Drozdova
authors.forename: E A
authors.initials: EA
authors.lastname: Zagorskaia
mesh_terms: D000818:Animals; D001769:Blood / Q000378:metabolism*; D001786:Blood Glucose / Q000032:analysis; D001798:Blood Proteins / Q000032:analysis; D003404:Creatinine / Q000097:blood; D004573:Electrolytes / Q000097:blood; D004798:Enzymes / Q000097:blood; D006112:Gravitation; D006706:Homeostasis; D006728:Hormones / Q000097:blood; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains; D013026:Space Flight
chemical_list: D001786:Blood Glucose; D001798:Blood Proteins; D004573:Electrolytes; D004798:Enzymes; D006728:Hormones; D008315:Malondialdehyde; D003404:Creatinine
vernacular_title: Gomeostaticheskie reaktsii krovi krys v éksperimente na biosputnike "Kosmos-1667".