title: Some aspects of the allergy to cow's milk. Morphological alterations of the jejunal mucosa.
abstract: Forty-four patients were studied at the Allergology and Pediatric Outpatient Services of the "Centro Habana" Pediatric Hospital. Allergy to cow's milk was demonstrated in these children by means of a detailed medical history, suppression diet and reexposition, lactose tolerance test, intradermal skin tests with casein extracts and the remaining proteins of cow's milk; finally, a careful study of the jejunal mucosas by means of biopsy was carried out, according to Townley and Barnes' method with a Crosby capsule. The skin reactivity was evident in children with allergy to cow's milk with tested extracts, mainly casein; in the control group this result was scarce or nil. Likewise, it was verified that there are morphological changes in the jejunal mucosa of children with allergy to cow's milk; these changes consist of partial atrophy of the villi, increase in the cell-infiltrate of the lamina propria and patchy areas. Our results are compared with the studies carried out by other authors and were statistically assessed.
authors.affiliation: Allergology Service, Hnos. Ameijeiras Clinical Surgical Hospital, Havana, Cuba.
authors.forename: M
authors.initials: M
authors.lastname: Gómez Chávez
authors.forename: A H
authors.initials: AH
authors.lastname: Gómez Echevarría
authors.forename: A
authors.initials: A
authors.lastname: Fernández Cállamo
authors.forename: A F
authors.initials: AF
authors.lastname: Valdés Sánchez
authors.forename: P
authors.initials: P
authors.lastname: Núñez Blanco
mesh_terms: D000293:Adolescent; D000818:Animals; D001942:Breast Feeding; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D005260:Female; D005512:Food Hypersensitivity / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000009:adverse effects; D007413:Intestinal Mucosa / Q000473:pathology; D007583:Jejunum / Q000473:pathology*; D008297:Male; D008892:Milk / Q000009:adverse effects*; D008894:Milk Proteins / Q000009:adverse effects
chemical_list: D008894:Milk Proteins