Genetic polymorphism of desialyzed alpha 2 HS-glycoprotein by ultrathin isoelectric focusing.
The genetically determined polymorphism of alpha 2 HS-glycoprotein was analyzed by immunoblotting ultrathin-layer polyacrylamide gel isoelectric focusing in the pH range 4-6.5 and neuraminidase pretreated sera. In a Libyan population sample from Tripoli (n = 110) three common phenotypes, alpha 2 HSG 1-1, 2-1, and 2-2, were observed. The allele frequencies were alpha 2 HSG1 = 0.8364 and alpha 2 HSG2 = 0.1636. The theoretical exclusion rate in cases of disputed paternity is 11.8%.
Sebetan
I M
IM
Department of Forensic Medicine, Tohoku University School of Medicine, Sendai, Japan.
Heshmat
M M
MM
D001798:Blood Proteins / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D007525:Isoelectric Focusing; D008002:Libya; D010641:Phenotype; D011110:Polymorphism, Genetic; D060749:alpha-2-HS-Glycoprotein
C556354:AHSG protein, human; D001798:Blood Proteins; D060749:alpha-2-HS-Glycoprotein