title: Laser Raman spectroscopic study of hereditary cataractous lenses in ICR/f-strain rat.
abstract: The lenses of ICR/f-strain rats with hereditary cataract were monitored in situ by laser Raman spectroscopy. The lenses used were within the age of 3-10 weeks before lens opacification became manifest. The reduction of protein SH group content and the increase of protein S-S bond content were observed in ICR/f rats in the precataractous stage. No significant change in the water content was observed.
authors.affiliation: Department of Biochemistry, Jikei University School of Medicine, Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Mizuno
authors.forename: E H
authors.initials: EH
authors.lastname: Kanematsu
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: N
authors.initials: N
authors.lastname: Ihara
mesh_terms: D000367:Age Factors; D000818:Animals; D002386:Cataract / Q000175:diagnosis* / Q000235:genetics; D004220:Disulfides / Q000032:analysis; D007834:Lasers; D007908:Lens, Crystalline / Q000032:analysis*; D051381:Rats; D013059:Spectrum Analysis, Raman
chemical_list: D004220:Disulfides