title: Granular mucosal lymphocytes in porcine small intestine.
abstract: A subpopulation of purified, interepithelial lymphocytes from porcine small intestinal mucosa contained cytoplasmic granules. Toluidine blue staining revealed metachromatic granules in 13.64% (606/4,450) cells. The cells had scant organelles, a single large nucleus with obvious invagination of the nuclear membrane, and prominent chromatin. Each cell contained 1 to 10 cytoplasmic membrane-bound granules, 0.6 to 1.5 micron in diameter. These findings indicated that the granular mucosal lymphocytes are related morphologically to mucosal mast cells. The presence of serotonin in the granules, confirmed by the serotonin releasing test, provided functional evidence that granular mucosal lymphocytes are related to mucosal mast cells.
authors.affiliation: Department of Pathology, Pig Research Institute, Taiwan, Chunan, Miaoli, ROC.
authors.forename: R M
authors.initials: RM
authors.lastname: Chu
authors.forename: S H
authors.initials: SH
authors.lastname: Wang
authors.forename: Y H
authors.initials: YH
authors.lastname: Du
mesh_terms: D000818:Animals; D007413:Intestinal Mucosa / Q000166:cytology*; D007421:Intestine, Small / Q000166:cytology*; D008214:Lymphocytes / Q000166:cytology* / Q000648:ultrastructure; D013552:Swine / Q000033:anatomy & histology*