Circadian rhythm with acrophase at night for urinary excretion of calcium and magnesium in childhood: population-based data of the cimitile study in southern Italy.
A population-based study on daily and overnight urine excretion of Ca and Mg was performed in 220 children aged 4-15 years living in Cimitile, Campania Region, Southern Italy. The Ca/creatinine and the Mg/creatinine ratio in overnight urine were significantly higher than in daily urine (p less than 0.01). This finding was also confirmed in hypercalciuric children. The Mg/Ca ratio in the general population was identical in daily and overnight urine while in the hypercalciuric group Mg/Ca in overnight urine was significantly higher (p less than 0.01) than in daily urine. The data point to the existence of a circadian rhythm with a peak at night for urine Ca and Mg excretion in children living in Cimitile and studied while attending to their everyday life.
DeSanto
N G
NG
Department of Pediatrics, 1st Faculty of Medicine, University of Naples, Italy.
DiIorio
B
B
Capasso
G
G
Capodicasa
G
G
Giordano
D R
DR
Aulisio
M
M
Paduano
C
C
Stamler
J
J
D000293:Adolescent; D002118:Calcium / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D002940:Circadian Rhythm; D003404:Creatinine / Q000652:urine; D005260:Female; D006801:Humans; D007558:Italy; D008274:Magnesium / Q000652:urine*; D008297:Male; D012737:Sex Factors
D003404:Creatinine; D008274:Magnesium; D002118:Calcium