[The genetic activity of an alkaline solution of formaldehyde].
Toxicity and genetic activity of disinfectant consisting of 1.5% paraform and 0.5% NaOH were studied. It was found that the preparation caused a weak mutagenic effect on Crepis capillaris and Chlorella roots, but had no effect in the Ames test and gonadal cells of mammals. The studies of mutagenic effect of the preparation on somatic cells of white mice show limits of the cytogenetic effect at the level of 3.5 g/kg (1/10 LD50).
Alekseenok
A Ia
AIa
D000468:Alkalies / Q000494:pharmacology; D000818:Animals; D002708:Chlorella / Q000187:drug effects / Q000235:genetics; D002869:Chromosome Aberrations; D004202:Disinfectants; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D005557:Formaldehyde / Q000494:pharmacology*; D019684:Magnoliopsida / Q000187:drug effects / Q000235:genetics; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests; D011108:Polymers / Q000494:pharmacology; D051381:Rats; D012475:Salmonella / Q000187:drug effects / Q000235:genetics; D012996:Solutions; D013090:Spermatocytes / Q000187:drug effects
D000468:Alkalies; D004202:Disinfectants; D004338:Drug Combinations; D011108:Polymers; D012996:Solutions; D005557:Formaldehyde; C003043:paraform
Geneticheskaia aktivnost' shchelochnogo rastvora formal'degida.