title: Intracavernous self-injection for erectile failure.
abstract: Thirty-three patients with erectile failure were taught to self-inject papaverine intracavernosally. The dose was from 15 to 80 mg. Phentolamine was added if 80 mg was not sufficient. The patients kept a diary on the effects of the regimen, and also filled out a questionnaire after a follow-up of 4-16 months. The results showed that 55% were satisfied with the method. However, technical difficulties were common. Sexual stimulation turned out to be very important resulting in varying erections on consecutive occasions with the same papaverine dose. Prolonged erection occurred once in 5 patients and was easily handled conservatively in all. Fibrous plaques developed in 2 patients. Twelve patients (36%) stopped the injections for various reasons. When failure occurred the disappointment was usually severe. Thus, the selection of patients for self-injection is important.
authors.affiliation: Eira Hospital, Helsinki, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Ruutu
authors.forename: B L
authors.initials: BL
authors.lastname: Lindström
authors.forename: J
authors.initials: J
authors.lastname: Virtanen
authors.forename: O
authors.initials: O
authors.lastname: Alfthan
mesh_terms: D000328:Adult; D000368:Aged; D003258:Consumer Behavior; D004359:Drug Therapy, Combination; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage* / Q000627:therapeutic use; D010410:Penile Erection / Q000187:drug effects*; D010646:Phentolamine / Q000008:administration & dosage / Q000627:therapeutic use; D012646:Self Administration
chemical_list: D010208:Papaverine; D010646:Phentolamine