Control of massive vesical hemorrhage due to radiation cystitis with intravesical instillation of 15 (s) 15-methyl prostaglandin F2-alpha.
Intravesical instillation of 15 (s) 15-methyl prostaglandin F2-alpha (1 mg in 100 ml of normal saline on days 1 and 2, and 0.5 mg in 50 ml of normal saline on days 3 and 4) controlled massive vesical hemorrhage due to radiation cystitis in a 60-year female with carcinoma of uterine cervix. With the 1 mg dose, she developed severe bladder spasms and mild fever. No cardiac or respiratory side effect was observed.
Hemal
A K
AK
Department of Urology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Vaidyanathan
S
S
Sankaranarayanan
A
A
Ayyagari
S
S
Sharma
P L
PL
D000368:Aged; D002260:Carboprost / Q000627:therapeutic use*; D003556:Cystitis / Q000150:complications* / Q000209:etiology; D005260:Female; D006417:Hematuria / Q000188:drug therapy / Q000209:etiology; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*; D001745:Urinary Bladder Diseases / Q000188:drug therapy* / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*
D011461:Prostaglandins F, Synthetic; D002260:Carboprost