title: Decision-making system (DMS) applied to hematology. Diagnosis of 180 cases of anemia secondary to a variety of hematologic disorders.
abstract: We have developed a new decision-making system which includes interpretation of complete blood count (CBC). The system works using Bayes' rule. We tested the CBC program for the diagnosis of 180 cases of anemia covering 20 benign and malignant hematological disorders. The data entered were obtained from a Coulter S + IV/HD and the interpretation of blood smears. Clinical information was not used. In 64.5% of cases, the correct diagnosis was displayed in first rank and in 20%, in second or third rank, giving a total of 84% of quite satisfactory responses. There were only 5% incorrect responses, but the proposed complementary tests rectified the error. Computer-aided diagnosis can help pathologists, clinicians, students, and technicians to make rapid correct diagnoses and choose the appropriate tests to perform. These programs run on IBM PC or similar microcomputers and are available from Coulter Electronics, Hialeah, FL.
authors.affiliation: Service Central d'Hèmatologie-Immunologie, Hôpital Henri Mondor, Créteil, France.
authors.forename: C
authors.initials: C
authors.lastname: Sultan
authors.forename: M
authors.initials: M
authors.lastname: Imbert
authors.forename: G
authors.initials: G
authors.lastname: Priolet
mesh_terms: D000740:Anemia / Q000175:diagnosis* / Q000209:etiology; D001772:Blood Cell Count; D003658:Decision Making, Computer-Assisted; D005103:Expert Systems; D006402:Hematologic Diseases / Q000150:complications / Q000175:diagnosis*; D006801:Humans