Radioisotopic method for nasal mucociliary function evaluation.
In 13 healthy young adults, nasal mucociliary transport velocity was measured by means of albumine microsphere labeled with Tc99m as a tracer. M + ISD of clearance velocity values and of the half time radioactivity (T1/2) resulted to be respectively 1.02 + 0.22 cm/min and 1.07 + 0.24 min. A significant correlation (P less than 0.05) between half time clearance (T1/2) values of the radioactive particles and the mucociliary velocity ones could be detected, making T1/2 a reliable and rapidly obtainable parameter for determining nasal mucociliary function. Advantages and disadvantages of the different techniques are discussed.
Paludetti
G
G
Dept. of O.R.L., University of Perugia, Italy.
Todisco
T
T
Fedeli
L
L
Giombini
E
E
Rosignoli
M
M
Almadori
G
G
D000328:Adult; D003947:Diagnostic Techniques, Radioisotope / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009079:Mucociliary Clearance; D012439:Saccharin; D013668:Technetium Tc 99m Aggregated Albumin; D013997:Time Factors
D013668:Technetium Tc 99m Aggregated Albumin; D012439:Saccharin