title: [Acute fibrinopenia in obstetrics].
abstract: A review of 10 cases of severe obstetrical haemorrhage is presented. The etiology is not always clear. The most significant biological sign is the early, acute and marked drop of fibrinogen levels, below 1 g in 20 p. cent of the cases and 0.5 g in 50 p. cent. An early and rapid treatment is essential and based on correcting the fibrinopenia; fibrinogen, in fractioned form, at a mean dose of 3 g, reduces the duration of the syndrome and minimize the risks of complications. In the acute phase, heparin therapy must be avoided because it might aggravate the haemorrhage.
authors.affiliation: Département d'Anesthésie-Réanimation, maternité Pellegrin, Bordeaux.
authors.forename: R
authors.initials: R
authors.lastname: Torrielli
authors.forename: F
authors.initials: F
authors.lastname: Boutin
authors.forename: M
authors.initials: M
authors.lastname: Rochet
authors.forename: P
authors.initials: P
authors.lastname: Neophytou
authors.forename: F
authors.initials: F
authors.lastname: Lahaye
mesh_terms: D000328:Adult; D001803:Blood Transfusion; D005260:Female; D005337:Fibrin / Q000032:analysis*; D005340:Fibrinogen / Q000032:analysis*; D006406:Hematoma / Q000150:complications; D006801:Humans; D010922:Placenta Diseases / Q000150:complications; D006473:Postpartum Hemorrhage / Q000097:blood*; D011247:Pregnancy; D012189:Retrospective Studies; D014593:Uterine Inertia / Q000150:complications
chemical_list: D005337:Fibrin; D005340:Fibrinogen
vernacular_title: Fibrinopénie aiguë en obstétrique.