title: Nonconvulsive status epilepticus with continuous diffuse spike-and-wave discharges during sleep in childhood.
abstract: On three epileptic conditions with common characteristics of almost continuous diffuse spike-and-wave discharges during sleep in EEG, clinical and electroencephalographic studies were undertaken to elucidate their pathophysiologies and interrelationships; namely on five cases of epilepsy with electrical status epilepticus during slow sleep (ESES), seven cases of a peculiar type of nonconvulsive status epilepticus in childhood (PNSE) and three cases of atypical benign partial epilepsy (ABPE). The dominant seizure types were absences and/or GTC in ESES, whereas they were focal motor seizures in PNSE and ABPE with more focalized epileptic discharges on EEGs than those in ESES. All the three conditions showed both features of generalized and partial epilepsies, although the former features were more prominent in ESES and the latter in PNSE and ABPE.
authors.affiliation: Department of Child Neurology, Okayama University Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kobayashi
authors.forename: N
authors.initials: N
authors.lastname: Murakami
authors.forename: H
authors.initials: H
authors.lastname: Yoshinaga
authors.forename: H
authors.initials: H
authors.lastname: Enoki
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtsuka
authors.forename: S
authors.initials: S
authors.lastname: Ohtahara
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D002540:Cerebral Cortex / Q000503:physiopathology; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000188:drug therapy; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology; D008297:Male; D012894:Sleep Stages / Q000502:physiology*; D013226:Status Epilepticus / Q000503:physiopathology*
chemical_list: D000927:Anticonvulsants