title: [Primary clinical, endoscopic and histologic findings in solitary rectal ulcer].
abstract: This study presents clinical, endoscopical and histological primary findings of solitary ulcer of the rectum obtained in 24 patients. Solitary ulcer of the rectum is preferably a disease of young women. The main symptom is recurrent rectal bleeding. Endoscopically in 50% of all cases mucosal ulcerations can be observed. The other cases are non-ulcerous lesions with uncharacteristic endoscopical findings. The majority of the lesions are within 6-8 cm of the anal margin. In 44% of the patients there are findings, which are suspicious of preexisting rectal prolapse. The histological main criterion is a fibromuscular hyperplasia of the lamina propria. Full agreement of endoscopical and histological diagnosis at primary examination could be obtained in only 17% of the cases.
authors.affiliation: Abteilung für Gastroenterologie/Hepatologie, Friedrich-Schiller-Universität Jena.
authors.forename: A
authors.initials: A
authors.lastname: Schneider
authors.forename: C
authors.initials: C
authors.lastname: Fritze
authors.forename: H
authors.initials: H
authors.lastname: Bosseckert
authors.forename: G
authors.initials: G
authors.lastname: Machnik
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007417:Intestinal Polyps / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011351:Proctoscopy; D012002:Rectal Diseases / Q000473:pathology*; D012004:Rectal Neoplasms / Q000473:pathology; D012007:Rectum / Q000473:pathology; D014456:Ulcer / Q000473:pathology*
vernacular_title: Klinische, endoskopische und histologische Erstbefunde beim solitären Rektumulkus.