[The effect of alpha-tocopherol on pulmonary surfactants].
Tocopherol deficiency in the rat organism stimulates activation of lipid peroxidation: the content of hydroperoxides in blood and surfactants of lungs tends to increase, the superweak glow of surfactant lipids enhances. In this case the surface activity of lung surfactants is lower than in the control. It also gets lower in hypervitaminosis rats. The data obtained may be used for development of approaches to the tocopherol (antioxidant) correlation of the lung surfactant system functioning.
Berezovskiĭ
V A
VA
Iakovleva
O A
OA
Gorchakov
V Iu
VIu
Mukalov
I O
IO
Khasabova
I A
IA
D000818:Animals; D015227:Lipid Peroxidation / Q000187:drug effects*; D049449:Luminescence; D008297:Male; D011663:Pulmonary Surfactants / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D014810:Vitamin E / Q000494:pharmacology*; D014811:Vitamin E Deficiency / Q000378:metabolism*
D011663:Pulmonary Surfactants; D014810:Vitamin E
Vliianie alpha-tokoferola na surfaktanty legkogo.