Absence of gradient of thyrotropin receptor antibody and T cell subset distribution between thyroid and peripheral venous blood in patients with Graves' disease prepared for surgery with carbimazole and potassium iodide.
The aim of the study was to examine tri-iodothyronine, thyroxine, thyroid antibody and thyrotropin receptor antibody levels in thyroid and peripheral venous blood at the time of surgery in patients with Graves' disease. T cell subset patterns in peripheral and thyroidal venous blood were compared to the distribution of T cell subset patterns within the thyroid gland itself. The results showed that at the time of surgery there were no significant differences in any of the parameters measured between thyroidal and peripheral venous samples. T cell subset patterns within the thyroid gland were subjectively similar to those in the venous samples.
Wilson
R
R
University Department of Medicine, Royal Infirmary, Glasgow, UK.
McKillop
J H
JH
Pearson
C
C
Burnett
A K
AK
Gunn
I
I
McNicol
A M
AM
Thomson
J A
JA
D001323:Autoantibodies / Q000032:analysis*; D002231:Carbimazole / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006111:Graves Disease / Q000097:blood / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D011193:Potassium Iodide / Q000627:therapeutic use; D011292:Premedication; D011989:Receptors, Thyrotropin / Q000276:immunology*; D013601:T-Lymphocytes / Q000145:classification*; D013961:Thyroid Gland / Q000276:immunology*
D001323:Autoantibodies; D011989:Receptors, Thyrotropin; D011193:Potassium Iodide; D002231:Carbimazole