title: Correlation of content of B cells and Leu7-positive cells with subtype and stage in lymphocyte predominance type Hodgkin's disease.
abstract: Cases of lymphocyte predominance type Hodgkin's disease were investigated using immunohistochemical methods and compared for morphological subtype and clinical stage. Cases of nodular paragranuloma showed a high, diffuse paragranuloma a moderate, and the mixed type a low, content of B cells. There was no significant correlation between B cell content and clinical stage. The number of Leu7+ cells was significantly increased in stage I of nodular paragranuloma. Hodgkin cells did not react with the CD15 antibody in most cases of paragranuloma but showed reactivity in the mixed type.
authors.affiliation: Institute of Pathology, University of Kiel, Federal Republic of Germany.
authors.forename: M L
authors.initials: ML
authors.lastname: Hansmann
authors.forename: C
authors.initials: C
authors.lastname: Fellbaum
authors.forename: P K
authors.initials: PK
authors.lastname: Hui
authors.forename: T
authors.initials: T
authors.lastname: Zwingers
mesh_terms: D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis*; D001402:B-Lymphocytes / Q000032:analysis*; D006689:Hodgkin Disease / Q000097:blood*; D006801:Humans; D007150:Immunohistochemistry
chemical_list: D000945:Antigens, Differentiation, T-Lymphocyte