title: Synthesis and antimicrobial activity of some pyrrole derivatives. III--2-(4-arylpiperazino)-3-ethoxycarbonyl-5-aryl-pyrrole derivatives.
abstract: The synthesis of 3-ethoxycarbonyl-5-aryl-pyrrole derivatives with an arylpiperazine group in position 2 is described. The in vitro biological investigation showed that compound (XVIII) had considerable antibacterial activity against gram-positive microorganisms and antifungal activity against Candida rugosa, while the other compounds did not show any significative activity.
authors.affiliation: Istituto di Chimica Farmaceutica, Tossicologica e Applicata, Università di Cagliari, Italy.
authors.forename: M T
authors.initials: MT
authors.lastname: Cocco
authors.forename: C
authors.initials: C
authors.lastname: Congiu
authors.forename: A
authors.initials: A
authors.lastname: Maccioni
authors.forename: M L
authors.initials: ML
authors.lastname: Schivo
authors.forename: A
authors.initials: A
authors.lastname: De Logu
authors.forename: G
authors.initials: G
authors.lastname: Palmieri
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D008826:Microbial Sensitivity Tests; D010879:Piperazines / Q000138:chemical synthesis* / Q000494:pharmacology; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D010879:Piperazines; D011758:Pyrroles