In situ hybridization of two cloned chromosome 7 sequences tightly linked to the cystic fibrosis locus.
Two DNA sequences closely linked to the cystic fibrosis locus have been sublocalized to 7q31.3----q32 by in situ hybridization. These findings are consistent with previously published maps of that region of human chromosome 7. The cystic fibrosis locus therefore maps to the 7q31.3----q32 region, a more distal location that had been inferred from previous data.
Duncan
A M
AM
Department of Pathology, Queen's University, Kingston, Ontario, Canada.
Buchwald
M
M
Tsui
L C
LC
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002897:Chromosomes, Human, Pair 7; D003550:Cystic Fibrosis / Q000235:genetics*; D015342:DNA Probes; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D009693:Nucleic Acid Hybridization
D015342:DNA Probes; D005819:Genetic Markers