title: Electrical stimulation of ligament healing. An experimental study of the patellar ligament of rabbits.
abstract: To examine the effects of direct electric current on ligament healing in rabbits, a full-thickness defect of the patellar ligament was electrically stimulated for time periods of up to seven weeks. The rabbits were randomly assigned to biomechanical and biochemical studies, and healing was evaluated by these parameters. Electrical stimulation was shown to restore tensile stiffness in a short period of time and to decrease the relative proportion of Type III collagen more rapidly than in the control group. However, electrical stimulation did not change the collagen content of newly formed tissue. Electricity enhances the repair process of the ligament by changing the ratio of collagen types.
authors.affiliation: Department of Orthopaedics, Ichihara Hospital, Teikyo University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Akai
authors.forename: H
authors.initials: H
authors.lastname: Oda
authors.forename: Y
authors.initials: Y
authors.lastname: Shirasaki
authors.forename: T
authors.initials: T
authors.lastname: Tateishi
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D003094:Collagen / Q000378:metabolism; D004599:Electric Stimulation Therapy; D008023:Ligaments, Articular / Q000378:metabolism / Q000502:physiology; D010329:Patella; D011817:Rabbits; D014945:Wound Healing
chemical_list: D003094:Collagen