[Influence of temperature on the function of the human testes].
The influence of temperature on human Leydig and Sertoli cell functions was investigated in vitro using the organ culture technique. Specific 125I-FSH and 125I-hCG binding sites in testes from patients with prostate cancer cultured for 1, 3, 5 or 7 days at 33 degrees C or 37 degrees C were measured and compared. There were no significant differences in 125I-FSH or 125I-hCG binding sites between the two temperature groups at 1 to 7 days of culture. Testosterone concentration in the medium obtained from testicular organ culture at 33 degrees C did not differ significantly from that at 37 degrees C at 1 to 7 days of culture. In conclusion, a high temperature may not disturb the Leydig and Sertoli cell functions in a short term.
Namiki
M
M
Department of Urology, Osaka Central Hospital.
Nakamura
M
M
Okuyama
A
A
Doi
Y
Y
Matsui
T
T
Fujisue
H
H
Takeyama
M
M
Fujioka
H
H
D000368:Aged; D006063:Chorionic Gonadotropin / Q000378:metabolism; D006801:Humans; D007985:Leydig Cells / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009924:Organ Culture Techniques; D012708:Sertoli Cells / Q000502:physiology; D013696:Temperature; D013737:Testis / Q000378:metabolism / Q000502:physiology*
D006063:Chorionic Gonadotropin