[Clinical evaluation of S 6472 granule preparation (sustained-release cefaclor) in chronic bronchitis].
The S 6472 granule preparation (sustained-release cefaclor preparation) was administered to 15 cases of chronic bronchitis for its clinical evaluation; a daily dosage of 750 mg was orally given in 2 divided doses after breakfast and dinner for a duration of 7 to 22 days. Clinical effects were good in 11 cases, fair in 1 case and poor in 3 cases. Among the 13 cases other than 2 unadaptable Pseudomonas infections, good effectiveness was found in 11 cases (efficacy rate: 84.6%). There appeared to be no side effects or abnormal laboratory test values due to administration of this drug.
Tanimoto
H
H
Department of Respiratory Diseases, Toranomon Hospital.
Nakamori
Y
Y
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000188:drug therapy* / Q000382:microbiology; D002433:Cefaclor / Q000008:administration & dosage / Q000627:therapeutic use*; D002506:Cephalexin / Q000031:analogs & derivatives*; D002908:Chronic Disease; D003692:Delayed-Action Preparations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D003692:Delayed-Action Preparations; D002433:Cefaclor; D002506:Cephalexin