title: Confirmation of avian sex-chromosome linkage of liver cytosolic aconitase (ACO1).
abstract: Frequencies of liver cytosolic aconitase (ACO1) allozyme phenotypes in female zebra finches (Poephila guttata) conformed to a sex-chromosome-linked model of inheritance. Since birds are characterized by female heterogamety (ZZ males, ZW females), the observed absence of female heterozygotes for the cytosolic aconitase gene is interpreted as suggesting linkage of the ACO1 locus to the Z chromosome and hemizygous expression of this locus. Confirmation of this linkage assignment provides further support for the concept of evolutionary conservation of the avian Z chromosome.
authors.affiliation: University of Texas M.D. Anderson Cancer Center, Smithville 78957.
authors.forename: J M
authors.initials: JM
authors.lastname: Lacson
authors.forename: D C
authors.initials: DC
authors.lastname: Morizot
mesh_terms: D000154:Aconitate Hydratase / Q000235:genetics* / Q000378:metabolism; D000483:Alleles; D000818:Animals; D001717:Birds / Q000235:genetics*; D002874:Chromosome Mapping; D003600:Cytosol / Q000201:enzymology*; D004592:Electrophoresis, Starch Gel; D005260:Female; D005786:Gene Expression Regulation; D005787:Gene Frequency; D008040:Genetic Linkage; D008099:Liver / Q000201:enzymology / Q000648:ultrastructure*; D008297:Male; D010641:Phenotype; D012730:Sex Chromosomes
chemical_list: D000154:Aconitate Hydratase