[Gynecologic interventions in von Willebrand-Jürgens syndrome (2 case reports)].
Gynecological procedures were performed in two patients with von Willebrand-Jürgens Syndrome. Although both patients were known to have the disorder and appropriate measures were taken, severe bleeding complications occurred in both cases, in the one shortly postoperatively and in the other after discharge from hospital. Based on our experience and a review of the literature, we recommend the following therapeutic concept: preoperative increase of vWF to over 50% and normalization of bleeding time by administration of FFP and AHF, postoperative substitution with 2-3 units FFP and 1-2 units AHF daily through the 15th day postsurgery.
Schmid
J
J
Frauenklinik Kantonsspitals Luzern.
Heiz
P
P
Riedler
G F
GF
D000328:Adult; D001780:Blood Coagulation Tests; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D011183:Postoperative Complications / Q000097:blood*; D014592:Uterine Hemorrhage / Q000097:blood*; D014945:Wound Healing; D014842:von Willebrand Diseases / Q000097:blood*; D014841:von Willebrand Factor / Q000378:metabolism
D014841:von Willebrand Factor
Gynäkologische Eingriffe bei von-Willebrand-Jürgens-Syndrom (2 Fallberichte).