Photocatalyzed anaerobic oxidation of nicotinamide coenzyme dimers to NAD+ by adriamycin.
The nicotinamide adenine dinucleotide dimers (NAD)2 obtained by electrochemical reduction of NAD+ are oxidized by adriamycin in anaerobic photocatalyzed reaction yielding NAD+ and 7-deoxyadriamycinone. Under the same conditions NADH is not oxidized.
Carelli
V
V
Institute of Pharmaceutical Chemistry and Toxicology, University of Rome "La Sapienza", Italy.
Casini
A
A
Finazzi-Agro
A
A
Liberatore
F
F
Tortorella
S
S
D000693:Anaerobiosis; D004317:Doxorubicin; D009243:NAD; D010084:Oxidation-Reduction; D010777:Photochemistry; D013053:Spectrophotometry
D009243:NAD; D004317:Doxorubicin