Reduction of a benzamidoxime derivative to the corresponding benzamidine in vivo and in vitro.
Hauptmann
J
J
Institute of Pharmacology and Toxicology, Medical Academy Erfurt, GDR.
Paintz
M
M
Kaiser
B
B
Richter
M
M
D000818:Animals; D001646:Bile / Q000032:analysis*; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D004151:Dipeptides; D066298:In Vitro Techniques; D007262:Infusions, Intravenous; D008099:Liver / Q000378:metabolism; D010084:Oxidation-Reduction; D010649:Phenylalanine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D010880:Piperidines / Q000378:metabolism* / Q000494:pharmacology; D011169:Portal Vein; D011817:Rabbits; D051381:Rats; D013917:Thrombin / Q000037:antagonists & inhibitors
D004151:Dipeptides; D010880:Piperidines; C058855:N(alpha)-(2-naphthylsulfonylglycyl)-4-oxamidinophenylalanine piperidide; D010649:Phenylalanine; C038708:N(alpha)-(2-naphthylsulfonylglycyl)-4-amidinophenylalanine piperidide; D013917:Thrombin