Action potential threshold elevation in the guinea-pig as a function of impact noise exposure energy.
Eighteen groups of guinea pigs were exposed to a simulated impact noise for periods of 1.5-24 h. The peak level was kept constant at 131.5 dB and the repetition rate was varied to give seven different equivalent levels (Leq) between 96 and 117 dB. The auditory thresholds were assessed by electrocochleography after 1 month and compared with those of a control group. Significant damage occurred even at the lowest exposure energy used. When the total exposure energy was expressed on a decibel scale, the threshold elevation (1-10 kHz) increased 1.07 dB for each decibel increase in the exposure energy, regardless of the combination of Leq and exposure time. The results of the study thus support the equal-energy hypothesis under these conditions.
Grenner
J
J
Department of Otolaryngology and Experimental Research, Malmö General Hospital, University of Lund, Sweden.
Nilsson
P
P
Sheppard
H
H
Katbamna
B
B
D000818:Animals; D001300:Audiometry, Evoked Response; D001309:Auditory Threshold; D005260:Female; D006168:Guinea Pigs; D006317:Hearing Loss, Noise-Induced / Q000503:physiopathology*; D009622:Noise