High-performance liquid chromatography separations of nitrosamines. III. Conformers of N-nitrosamino acids.
The separation of a selected group of N-nitrosamino acids and their syn and anti conformers by high-performance liquid chromatography using an alpha-cyclodextrin bonded silica gel column and a mobile phase of acetonitrile-triethylammonium acetate was achieved. The effects of mobile phase pH and concentration of acetonitrile on resolution and elution times are also reported.
Issaq
H J
HJ
Program Resources, Inc., NCI-Frederick Cancer Research Facility, MD 21701.
Williams
D G
DG
Schultz
N
N
Saavedra
J E
JE
D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D006863:Hydrogen-Ion Concentration; D008968:Molecular Conformation; D009602:Nitrosamines / Q000302:isolation & purification*; D013237:Stereoisomerism
D009602:Nitrosamines