title: Maternal arterial desaturation with 15-methyl prostaglandin F2 alpha for uterine atony.
abstract: Over a six-month period, five women with severe uterine atony and postpartum hemorrhage developed marked maternal arterial oxygen desaturation within five to ten minutes of the administration of 15-methyl prostaglandin F2 alpha. The average fall from baseline was 10.4 +/- 5.4%, to a mean arterial oxygen saturation of 88.8 +/- 5.45%. The desaturation was accompanied by acute increases, averaging 20.7 +/- 5.9%, in the intrapulmonary shunt.
authors.affiliation: Department of Obstetrics and Gynecology, Wilford Hall United States Air Force Medical Center, Lackland Air Force Base, Texas.
authors.forename: G D
authors.initials: GD
authors.lastname: Hankins
authors.forename: G K
authors.initials: GK
authors.lastname: Berryman
authors.forename: R T
authors.initials: RT
authors.lastname: Scott
authors.forename: D
authors.initials: D
authors.lastname: Hood
mesh_terms: D001784:Blood Gas Analysis; D002260:Carboprost / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010092:Oximetry; D010100:Oxygen / Q000097:blood*; D006473:Postpartum Hemorrhage / Q000097:blood*; D011247:Pregnancy; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects*; D013997:Time Factors; D014593:Uterine Inertia / Q000097:blood* / Q000150:complications / Q000188:drug therapy
chemical_list: D011461:Prostaglandins F, Synthetic; D002260:Carboprost; D010100:Oxygen