Persistent synovial lymphocyte responses to mumps and adenovirus antigens.
A man in his 50s with rheumatoid arthritis showed maximal synovial lymphocyte reactivity to mumps antigen on 9 of 10 testings over a period of 6 years; peripheral blood lymphocytes showed no significant responses to mumps antigen in 5 testings over 5 years. A boy of 15 with recurrent arthritis of the right knee showed maximal synovial lymphocyte reactivity to adenovirus antigen. This reactivity was again present during a subsequent episode more than 3 years later; peripheral blood lymphocytes showed no such response to adenovirus antigen.
Ford
D K
DK
Department of Medicine, University of British Columbia, Vancouver, Canada.
Stein
H B
HB
Schulzer
M
M
D000260:Adenoviruses, Human / Q000276:immunology*; D000956:Antigens, Viral / Q000032:analysis*; D001172:Arthritis, Rheumatoid / Q000276:immunology; D002648:Child; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009109:Mumps virus / Q000276:immunology*; D013582:Synovial Fluid / Q000276:immunology*; D013997:Time Factors
D000956:Antigens, Viral