Human corticotropin releasing hormone gene is located on the long arm of chromosome 8.
The chromosomal locus of the human corticotropin releasing hormone (hCRH) gene was assigned to chromosome 8 using Southern blot analysis of human x rodent cell hybrids and was localized to band 8q13 using in situ hybridization to metaphase chromosomes. The absence of secondary hybridization strongly suggests that hypothalamic and placental CRH are transcribed from the same gene.
Arbiser
J L
JL
Howard Hughes Medical Institute, Department of Genetics, Brigham and Women's Hospital, Boston, MA 02115.
Morton
C C
CC
Bruns
G A
GA
Majzoub
J A
JA
D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002898:Chromosomes, Human, Pair 8; D003346:Corticotropin-Releasing Hormone / Q000235:genetics*; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000235:genetics; D006801:Humans; D006822:Hybrid Cells; D007621:Karyotyping; D051379:Mice; D009693:Nucleic Acid Hybridization
D004247:DNA; D003346:Corticotropin-Releasing Hormone