Voluntary control of an ileal pouch by coordinated electrical stimulation. A pilot study in the dog.
Ileal reservoirs were constructed in four dogs under general anesthesia and stimulated by means of a constant current generator that produced pulse trains at frequencies between 6 Hz and 1.67 kHz. Stimulation at 6 Hz with 50 ms pulses between amplitudes of 15 and 25 mA uniformly produced pouch contraction and reservoir emptying. Stimulation at other frequencies did not cause pouch emptying although pressure increases were sometimes observed. Such electrical stimulation may be useful for voluntary control of intestinal reservoirs when used as replacement for urinary bladder or colon. The mechanism by which the intestinal contraction is produced appears to be different than that produced by slow wave pacing.
Grundfest-Broniatowski
S
S
Department of General Surgery, Cleveland Clinic Foundation, Ohio 44106.
Moritz
A
A
Ilyes
L
L
Jacobs
G
G
Kasick
J
J
Olsen
E
E
Nose
Y
Y
D000714:Anastomosis, Surgical; D000818:Animals; D004285:Dogs; D004599:Electric Stimulation Therapy / Q000379:methods*; D004567:Electrodes, Implanted; D005769:Gastrointestinal Motility; D007082:Ileum / Q000502:physiology / Q000601:surgery*; D010528:Peristalsis