title: Response to intradermal skin testing with four cat allergen preparations in healthy and allergic dogs.
abstract: Intradermal skin testing with 4 cat allergens was performed on 40 dogs. The allergens used were a commercial preparation, cat allergen 1, cat pelt extract, and cat serum. Twenty dogs had inhalant allergies (canine atopy) and 20 dogs were healthy. The dogs in these 2 groups were further allotted to groups of dogs with or without exposure to cats. Cat pelt extract was the only allergen that caused a statistically significant (P less than 0.025) difference in the number of positive reactions in healthy vs allergic dogs, with healthy dogs having the greater number of positive reactions. Seven (35%) of the 20 dogs with no known exposure to cats had positive reactions to at least one of the allergens. In dogs that had been exposed to cats, positive reactions developed in twice the number of dogs without clinical signs of canine atopy, compared with those with clinical signs of canine atopy. These data showed that dogs do become sensitized to cat allergen, but that this sensitization may not indicate known exposure to cats or clinical disease.
authors.affiliation: Department of Medicine, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536.
authors.forename: S D
authors.initials: SD
authors.lastname: White
authors.forename: J L
authors.initials: JL
authors.lastname: Ohman
mesh_terms: D000485:Allergens / Q000276:immunology*; D000818:Animals; D002415:Cats; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D006967:Hypersensitivity / Q000175:diagnosis / Q000662:veterinary*; D007428:Intradermal Tests / Q000662:veterinary*; D012882:Skin Tests / Q000662:veterinary*
chemical_list: D000485:Allergens