title: An ultrastructural study of centriolar complexes in adult and embryonic human aortic endothelial cells.
abstract: Ultrastructural organization of centriolar complexes in 90 adult human aortic endothelial cells from uninvolved areas, fibrous and atheromatous plaques and 30 endothelial cells from human embryonic aorta were studied using serial sections. Primary cilia protruding from the abluminal cell surface were found on 28 of 30 endothelial cells from atheromatous plaques. Only five of 30 cells from either fibrous plaques or uninvolved areas developed primary cilia protruding to the lumen. Impaired primary cilia entirely immersed into the cytoplasm were found in embryonic endothelial cells. It was speculated that both the modes of formation and the functions of endothelial cilia in embryonic and adult aortas are different.
authors.affiliation: Institute of Experimental Cardiology, USSR Cardiology Research Center, AMS of the USSR, Moscow.
authors.forename: V B
authors.initials: VB
authors.lastname: Bystrevskaya
authors.forename: V V
authors.initials: VV
authors.lastname: Lichkun
authors.forename: A S
authors.initials: AS
authors.lastname: Antonov
authors.forename: N A
authors.initials: NA
authors.lastname: Perov
mesh_terms: D001011:Aorta / Q000166:cytology / Q000196:embryology; D002502:Centrioles / Q000648:ultrastructure*; D004622:Embryo, Mammalian / Q000166:cytology*; D004730:Endothelium, Vascular / Q000166:cytology* / Q000196:embryology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged