Differences in biodistribution in rats injected with 99mTc-MDP preparations with different stabilizing agents.
The biodistribution of four 99mTc labelled MDP preparations with different stabilizing agents were studied in young rats. The study was performed with MDP gentisic acid as a standard versus MDP ascorbic acid and MDP PABA. All results were tested statistically by the Wilcoxon-van-Eltern test.
Heggli
D E
DE
Institute of Energy Technology, Kjeller, Norway.
Franco
P
P
Nørbygaard
E
E
D010129:4-Aminobenzoic Acid; D000818:Animals; D001205:Ascorbic Acid; D005079:Excipients; D005841:Gentisates; D062385:Hydroxybenzoates; D051381:Rats; D013669:Technetium Tc 99m Medronate / Q000493:pharmacokinetics*; D014018:Tissue Distribution
D005079:Excipients; D005841:Gentisates; D062385:Hydroxybenzoates; D001205:Ascorbic Acid; D010129:4-Aminobenzoic Acid; C010925:2,5-dihydroxybenzoic acid; D013669:Technetium Tc 99m Medronate