title: In vitro susceptibility of Trichomonas vaginalis to 50 antimicrobial agents.
abstract: We determined the susceptibilities of five strains of Trichomonas vaginalis, one of which was metronidazole resistant, to 50 antimicrobial agents. For the metronidazole-susceptible strains, the most active agents were metronidazole, tinidazole, mebendazole, furazolidone, and anisomycin. Against the resistant strain mebendazole, furazolidone, and anisomycin were the most active. Antifungal agents, beta-lactams, macrolides, aminoglycosides, and folic acid antagonists were ineffective against all strains.
authors.affiliation: Department of Medicine, Wyman Park Health System, Baltimore, Maryland 21211.
authors.forename: S D
authors.initials: SD
authors.lastname: Sears
authors.forename: J
authors.initials: J
authors.lastname: O'Hare
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D000981:Antiprotozoal Agents / Q000494:pharmacology; D004351:Drug Resistance; D005493:Folic Acid Antagonists / Q000494:pharmacology; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D014246:Trichomonas vaginalis / Q000187:drug effects*
chemical_list: D000871:Anthelmintics; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000981:Antiprotozoal Agents; D005493:Folic Acid Antagonists; D008795:Metronidazole