Effects of an extract of feverfew (Tanacetum parthenium) on arachidonic acid metabolism in human blood platelets.
It has been suggested that feverfew extracts (FE) inhibit platelet behaviour via effects on platelet sulphydryl (SH) groups. In the present study we found evidence that FE inhibits uptake as well as liberation of arachidonic acid (AA) into/from platelet membrane phospholipids (PL).
Loesche
W
W
Institute of Pathological Biochemistry, Medical Academy of Erfurt, GDR.
Groenewegen
W A
WA
Krause
S
S
Spangenberg
P
P
Heptinstall
S
S
D001095:Arachidonic Acids / Q000097:blood*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D013917:Thrombin / Q000502:physiology
D001095:Arachidonic Acids; D010936:Plant Extracts; D013917:Thrombin