title: [Modification of the regulatory effects of thymocytes on hematopoiesis in irradiated mice as affected by heterologous immunoglobulin G and low-dose ionizing radiation].
abstract: The administration of heterologous immunoglobulin G (IgG) and/or exposure of mouse thymocyte donors to 1 and 2 Gy radiation were shown to change the regulatory effects of thymus lymphocytes on the recovery of haemopoiesis in syngeneic recipients irradiated with a median lethal dose of 6 Gy. Thymocytes of exposed (2 Gy) donors produced a stimulatory effect on the restoration of the myelokaryocytes number and increased the number of endogenous splenic colonies and bone marrow CFUs in animals exposed to a median lethal dose, whereas the administration of IgG to thymocyte donors given 2 Gy eliminated the stimulatory effect of thymocytes on the number of myelokaryocytes, and the amount of CFUs in irradiated recipients decreased.
authors.forename: V G
authors.initials: VG
authors.lastname: Lebedev
authors.forename: B B
authors.initials: BB
authors.lastname: Moroz
authors.forename: K K
authors.initials: KK
authors.lastname: Gutsenko
authors.forename: A A
authors.initials: AA
authors.lastname: Ivanov
mesh_terms: D000818:Animals; D000910:Antibodies, Heterophile / Q000008:administration & dosage*; D006410:Hematopoiesis; D006736:Horses / Q000276:immunology; D007074:Immunoglobulin G / Q000008:administration & dosage*; D008297:Male; D051379:Mice; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D013601:T-Lymphocytes / Q000502:physiology*
chemical_list: D000910:Antibodies, Heterophile; D007074:Immunoglobulin G
vernacular_title: Modifikatsiia reguliatornykh éffektov timotsitov na gemopoéz obluchennykh mysheĭ pod vliianiem geterologichnogo immunoglobulina G i ioniziruiushchego izlucheniia v maloĭ doze.