Treatment of habitual abortions associated with autoimmune abnormalities. A report of two cases.
In a study of the etiology of idiopathic habitual abortion, we have found 2 patients with a history of 5 and 4 spontaneous abortions respectively, possibly caused by autoimmune abnormalities. In the plasma of one of the patients we had found the presence of lupus anticoagulans and other lupus antibodies, whereas the other suffered from a latent autoimmune hepatitis. We describe the successful treatment of the 2 womens' subsequent pregnancies with subcutaneous heparin supplemented with acetylsalicylic acid.
Christiansen
O B
OB
Department of Clinical Immunology, Aalborg Hospital, Denmark.
Andersen
E S
ES
Lauritsen
J G
JG
Grunnet
N
N
D000026:Abortion, Habitual / Q000276:immunology*; D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D011247:Pregnancy
D001323:Autoantibodies; D006493:Heparin; D001241:Aspirin