HLA-B27 associated dactylitis in children.
A number of conditions have been found to be associated with the HLA-B27 locus including ankylosing spondylitis, psoriatic spondylitis, Reiter's syndrome, juvenile arthritis, and others. An unusual clinical syndrome of "sausage-like" toe, or dactylitis, associated with an oligoarthritis involving the lower extremities has been reported in adults, as has HLA-B27 associated spondyloarthritis and enthesopathy in children. We describe 3 children with dactylitis of the toe who carry HLA-B27. Their course and treatment are presented, and the importance of establishing this diagnostic entity is discussed.
Siegel
D M
DM
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14621.
Baum
J
J
D000293:Adolescent; D001168:Arthritis / Q000276:immunology* / Q000503:physiopathology; D002648:Child; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015796:HLA-B27 Antigen; D006801:Humans; D007866:Leg; D008297:Male; D010146:Pain; D014033:Toe Joint / Q000276:immunology* / Q000503:physiopathology
D006680:HLA Antigens; D015796:HLA-B27 Antigen