Mechanical induction of osteogenesis: the importance of pin rigidity.
Eight dogs, divided into two groups of four by varying pin rigidity, underwent 15% left tibial lengthening by the Ilizarov method. In group I, "tensioned" 1.6-mm wires maintained a rigidity approaching that of 4.0-mm pins. In group II, the wires, maintained at half the tension, averaged 45% of the rigidity measured in group I. All dogs in group I filled the experimental gap with de novo osteogenesis, whereas all of the dogs in group II prematurely bridged the gap, arresting the process of osteogenesis. From these experimental results, clinical trials have been started using commercially available external fixation devices utilizing pins with equivalent rigidity.
Aronson
J
J
Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock.
Harrison
B
B
Boyd
C M
CM
Cannon
D J
DJ
Lubansky
H J
HJ
D000293:Adolescent; D000818:Animals; D001696:Biomechanical Phenomena; D001852:Bone Lengthening / Q000295:instrumentation*; D001858:Bone Nails; D002118:Calcium / Q000032:analysis; D003094:Collagen / Q000032:analysis; D003720:Densitometry; D004285:Dogs; D005069:Evaluation Studies as Topic; D005097:Exostoses, Multiple Hereditary / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D009989:Orthotic Devices; D010012:Osteogenesis; D010027:Osteotomy; D011897:Random Allocation; D013718:Tensile Strength; D013977:Tibia; D013997:Time Factors
D003094:Collagen; D002118:Calcium