[Preliminary analysis of inheritance of scoliosis].
90 pedigrees (283 individuals) were used for statistical and segregation analysis of scoliosis inheritance. It was shown that inheritance of scoliosis may be described by the monogenic model with incomplete penetrance of heterozygotes, the latter being lower in men than in women. The monogenic model allows to perform correct predictions, the probability of incorrect prediction being about 0.1.
Aksenovich
T I
TI
Semenov
I R
IR
Ginzburg
E Kh
EKh
Zaĭdman
A M
AM
D005260:Female; D005787:Gene Frequency; D006801:Humans; D008297:Male; D008957:Models, Genetic; D010641:Phenotype; D012600:Scoliosis / Q000235:genetics*
Predvaritel'nyĭ analiz nasledovaniia skolioza.