title: Metopic sutural closure in the human skull.
abstract: The present study reveals the presence in the sutural area of secondary cartilage, assuring the passive growth of the bones and undergoing an endochondral ossification, but without playing a direct role in the synostosis. The chondroid tissue is responsible for the growth of each frontal bone towards the other and constitutes the first bridge of union between the two bones. It is the most important finding in this study, which provides a description of the closure of the metopic suture and of the maintenance of an open sutural space by a process of active resorption. This new knowledge will help to understand better the whole process of suture closure and its pathology.
authors.affiliation: Human Anatomy Research Unit, Catholic University of Louvain, Brussels, Belgium.
authors.forename: M C
authors.initials: MC
authors.lastname: Manzanares
authors.forename: M
authors.initials: M
authors.lastname: Goret-Nicaise
authors.forename: A
authors.initials: A
authors.lastname: Dhem
mesh_terms: D002356:Cartilage / Q000033:anatomy & histology; D003393:Cranial Sutures / Q000033:anatomy & histology* / Q000196:embryology / Q000254:growth & development; D005333:Fetus / Q000033:anatomy & histology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008852:Microradiography; D012886:Skull / Q000033:anatomy & histology*