title: Compounds with potential antitumor activity. VI--2-Alkyl-3-[2-(1,3,4-thiadiazolyl)]-4-thiazolidinones.
abstract: The antitumor activity of a series of 2-alkyl-3-[2-(1,3,4-thiadiazolyl)]-4-thiazolidinones was tested against the leukemic P 388 tumor system in mice. Only compounds (V-VII) showed significant activity.
authors.affiliation: Dipartimento Farmaco-Chimico, Cattedra di Chimica Farmaceutica, Università di Messina, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Grasso
authors.forename: A
authors.initials: A
authors.lastname: Chimirri
authors.forename: P
authors.initials: P
authors.lastname: Monforte
authors.forename: G
authors.initials: G
authors.lastname: Fenech
authors.forename: M
authors.initials: M
authors.lastname: Zappalà
authors.forename: A M
authors.initials: AM
authors.lastname: Monforte
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D007941:Leukemia P388 / Q000188:drug therapy; D008055:Lipids / Q000032:analysis; D051379:Mice; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D008055:Lipids; D013830:Thiadiazoles