Effect of phenylpropanolamine on diet selection in rats.
Four doses of phenylpropanolamine (PPA; i.e., dl-norephedrine: 2.5, 5, 10, and 20 mg/kg) and saline were injected intraperitoneally in female rats maintained on a dietary self-selection paradigm. Intake of all three macronutrients (carbohydrate, fat, and protein) was equally affected by high doses of PPA. Lower doses decreased fat and protein more than carbohydrate.
Schwartz
D H
DH
Department of Psychology, Princeton University, NJ 08544.
Hoebel
B G
BG
D000818:Animals; D004032:Diet; D004305:Dose-Response Relationship, Drug; D005247:Feeding Behavior / Q000187:drug effects*; D005260:Female; D010665:Phenylpropanolamine / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D010665:Phenylpropanolamine