The association between ankylosing spondylitis, acute anterior uveitis and HLA-B27: the results of a Swiss family study.
Patients with HLA-B27 positive ankylosing spondylitis (AS) in a Swiss family study developed non-granulomatous acute anterior uveitis (AAU) 11 times more often than their healthy relatives sharing the same HLA-B27 positive haplotype (4.4% versus 0.4%; p less than 0.01) during a period of 6 months.
van der Linden
S M
SM
Department of Clinical Medicine, University Hospital, Maastricht, The Netherlands.
Rentsch
H U
HU
Gerber
N
N
Cats
A
A
Valkenburg
H A
HA
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D015796:HLA-B27 Antigen; D006239:Haplotypes; D006801:Humans; D008875:Middle Aged; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000235:genetics / Q000276:immunology; D014606:Uveitis, Anterior / Q000150:complications* / Q000235:genetics / Q000276:immunology
D006680:HLA Antigens; D015796:HLA-B27 Antigen