The clinical and radiological evaluation of lissencephaly.
Lissencephaly is a rare congenital malformation of the brain that has characteristic clinical and radiographic findings. Thirteen cases of lissencephaly were studied clinically and radiographically with computed tomography and magnetic resonance imaging. A classification was developed based on the findings in these cases and the literature. The clinical and radiographic evaluation of lissencephaly is emphasized, with a thorough discussion of the clinical spectrum of each type, radiographic findings, prognosis, survival, and associated genetic abnormalities.
Byrd
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SE
Bohan
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Osborn
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D001921:Brain / Q000000981:diagnostic imaging*; D002540:Cerebral Cortex / Q000002:abnormalities* / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed