title: A glucose sensor utilising tetracyanoquinodimethane as a mediator.
abstract: This paper describes an amperometric enzyme electrode for glucose analysis. The electrode utilised the mediator tetracyanoquinodimethane (TCNQ) to facilitate electron transfer from glucose oxidase to a pyrolytic graphite carbon electrode. The electrode demonstrated a response to glucose in a clinically relevant range (0-70 mM). Results concerning the direct current cyclic voltammetry of TCNQ and the electrodes' response to glucose, pH profile and the effect of temperature are presented.
authors.affiliation: Bioelectronics Division, Cranfield Institute of Technology, United Kingdom.
authors.forename: S P
authors.initials: SP
authors.lastname: Hendry
authors.forename: A P
authors.initials: AP
authors.lastname: Turner
mesh_terms: D015374:Biosensing Techniques; D004563:Electrochemistry; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D005949:Glucose Oxidase; D006863:Hydrogen-Ion Concentration; D009570:Nitriles; D013696:Temperature
chemical_list: D009570:Nitriles; C013703:tetracyanoquinodimethane; D005949:Glucose Oxidase; D005947:Glucose