Histological reactions of human endometrium to the IUD.
A comparative study was made of four intrauterine contraceptive devices: the Nova-T, MLCu250 Short, MLCu375 and the Gyne T. An endometrial biopsy was performed on the 25th day of the menstrual cycle. The tissue obtained was analyzed to determine endometrial morphology patterns. After two years of IUD use, no inflammatory changes were demonstrated with MLCu375. Histological responses of the endometrium to the IUD depend on the amount of copper in the IUD.
de Castro
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Hospital La Paz, Departmento de Obstetricia y Ginecologia, Madrid, Spain.
Contreras
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F
D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D004716:Endometritis / Q000209:etiology; D004717:Endometrium / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007435:Intrauterine Devices, Copper / Q000009:adverse effects*; D011960:Receptors, Estrogen / Q000502:physiology; D011980:Receptors, Progesterone / Q000502:physiology; D013997:Time Factors
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone