Combined treatment of immune nephropathies with plasmapheresis and immunosuppressants.
The treatment of patients with immune nephropthies is discussed: rapidly progressive nephritis, lupus nephropathy, Wegener granulomatosis, Goodpasture syndrome, Schonlein-Henoch nephritis. A combined treatment of plasmapheresis and immunosuppressants is applied. A definite result, specially with the cases of Wegener granulomatosis, is registered for certain number of the patients. Together with the usual tests: CIC, immunoglobulins, complement, etc. a method for controlling of the detoxic efficiency of the treatment is suggested. This is a biologic method- the level of paramecium caudatum in media from patients' plasma is registered in relation to time. After plasmapheresis the life of paramecium caudatum is considerably prolonged.
Nenov
D
D
Medical Academy, Clinic of Nephrology and Hemodialysis, Immunologic Laboratory, Varna, Bulgaria.
Metodiev
K
K
D000293:Adolescent; D000328:Adult; D000818:Animals; D000936:Antigen-Antibody Complex / Q000378:metabolism; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007074:Immunoglobulin G / Q000378:metabolism; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007674:Kidney Diseases / Q000276:immunology / Q000628:therapy*; D008297:Male; D010247:Paramecium / Q000276:immunology; D010956:Plasmapheresis
D000936:Antigen-Antibody Complex; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents