title: [Use of standardized oral hygiene in the prevention and therapy of mucositis in patients treated with radiochemotherapy of head and neck neoplasms].
abstract: Aseptic mucositis is a regularly occurring complication during radiochemotherapy of head and neck cancer. In case of a superinfection with pathogenic microorganisms the degree of mucositits can make an interruption of cancer therapy imperative. It may also cause severe complications such as fulminating fatal infection, local spreading to the oesophagus and even mediastinitis as well as disseminated fungal infections. We investigated the effect of the systematic local combined application of H202, povidone iodine, nystatine and dexpanthenol solution for the prophylaxis and therapy of mucositis induced by radiochemotherapy. During 16 months of application of our scheme symptoms of mucositis appeared only to a minor extent. No interruption of radiochemotherapy was necessary at any time.
authors.affiliation: Univ.-Hals-Nasen-Ohrenklinik und Poliklinik rechts der Isar (TU) München.
authors.forename: C
authors.initials: C
authors.lastname: Hasenau
authors.forename: B P
authors.initials: BP
authors.lastname: Clasen
authors.forename: D
authors.initials: D
authors.lastname: Roettger
mesh_terms: D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D009061:Mouth Mucosa / Q000187:drug effects / Q000528:radiation effects; D009910:Oral Hygiene / Q000379:methods*; D011832:Radiation Injuries / Q000628:therapy*; D013280:Stomatitis / Q000139:chemically induced / Q000628:therapy*
vernacular_title: Anwendung einer standardisierten Mundpflege zur Prophylaxe und Therapie einer Mukositis bein Patienten während der Radiochemotherapie von Kopf-Hals-Malignomen.