title: Food deprivation affects reproduction in adult female mice (Mus musculus) and the age of puberty for their female progeny.
abstract: Three experiments were designed to test the effects of food deprivation during various phases of the reproductive cycle on fertility and fecundity of the dams and on the age of sexual maturation and body growth of their female progeny. Food deprivation consisted of removal of all food every other day. Animals were deprived of food either during the period prior to pairing, during the period between pairing and conception or during gestation. Both fertility and fecundity were affected by food deprivation in some, but not all manipulations. The female progeny of food-deprived females reached puberty significantly later than the progeny of non-deprived dams when the food deprivation occurred during the week prior to pairing and up until successful insemination after pairing with a fertile male, but not when food deprivation occurred at other times during the reproductive cycle. Body growth did not differ in the daughters of food-deprived dams across the treatments for any of the experiments.
authors.affiliation: Biology Department, Williams College, Williamstown, MA 01267.
authors.forename: L C
authors.initials: LC
authors.lastname: Drickamer
authors.forename: D B
authors.initials: DB
authors.lastname: Meikle
mesh_terms: D000818:Animals; D005260:Female; D005298:Fertility; D005508:Food Deprivation / Q000502:physiology*; D051379:Mice; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012098:Reproduction