Dexamethasone-induced serum biochemical changes in goats.
Dexamethasone was administered at sequential dosages of 0.1 mg/kg/day for 3 days and 1 mg/kg/day for 3 days to 6 adult female goats. The greatest effects induced were hypokalemia, hypophosphatemia, and hyperglycemia. At low dosages of dexamethasone, transient increases (P less than 0.05) developed in serum sodium and chloride concentrations. An effect on hepatic physiology or iron metabolism was not observed.
Maddux
J M
JM
Department of Pathobiology, University of Tennessee, Knoxville 37901.
Moore
W E
WE
Keeton
K S
KS
Shull
R M
RM
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002712:Chlorides / Q000097:blood; D003907:Dexamethasone / Q000008:administration & dosage / Q000494:pharmacology*; D004573:Electrolytes / Q000097:blood*; D005260:Female; D006041:Goats / Q000097:blood*; D010758:Phosphorus / Q000097:blood; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood
D001786:Blood Glucose; D002712:Chlorides; D004573:Electrolytes; D010758:Phosphorus; D003907:Dexamethasone; D012964:Sodium; D011188:Potassium