title: A superior analysis of coenzyme Q10 in blood of humans, rabbits and rats for research.
abstract: The quantitative analysis of coenzyme Q10 (CoQ10) in samples of whole human blood has been refined to allow a 2- to 3-fold increase in the number of analyses per day, and reduction of cost to approximately 15% of the previous cost. The method is simple yet maintains reliability. The standard error was 0.2% (n = 6). The variation in blood levels of CoQ10 for human subjects for each of three months was approximately 5% in comparison with the control value (n = 5). For 30 human males, of 18-50 years (26 +/- 6) in age, and for 30 human females, of 18-50 years (26 +/- 9), the mean blood level of CoQ10 was 0.71 +/- 0.13 microgram/ml and 0.70 +/- 0.18 microgram/ml respectively. The mean blood levels of CoQ10 of rabbits (n = 28) was 0.29 +/- 0.07 micrograms/ml, and that for rats (n = 29) was 0.23 +/- 0.03 micrograms/ml.
authors.affiliation: Institute for Biomedical Research, University of Texas, Austin 78712.
authors.forename: K
authors.initials: K
authors.lastname: Muratsu
authors.forename: J
authors.initials: J
authors.lastname: Komorowski
authors.forename: Z X
authors.initials: ZX
authors.lastname: Shen
authors.forename: K
authors.initials: K
authors.lastname: Folkers
mesh_terms: D000328:Adult; D000375:Aging; D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002855:Chromatography, Thin Layer / Q000379:methods; D003067:Coenzymes; D005260:Female; D006801:Humans; D008297:Male; D008832:Microchemistry; D008875:Middle Aged; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D013045:Species Specificity; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D003067:Coenzymes; D014451:Ubiquinone; C024989:coenzyme Q10