title: Anthelmintic efficacies of fenbendazole, ivermectin, and levamisole against Nematodirus battus infections in lambs.
abstract: Anthelmintic efficacies of fenbendazole, ivermectin, and levamisole were evaluated against naturally acquired infections of Nematodirus battus in lambs. Four groups of 10 lambs each were used. Oral administration of 8 mg of levamisole/kg of body weight or 5 mg of fenbendazole/kg significantly (P less than 0.01) reduced the degree of infection by N battus (adults) by greater than 99%. An oral formulation of 200 micrograms of ivermectin/kg was 98% effective (P less than 0.01). Numbers of other Nematodirus spp (including N filicollis and N spathiger) were significantly reduced.
authors.affiliation: College of Veterinary Medicine, Oregon State University, Corvallis 97331.
authors.forename: G L
authors.initials: GL
authors.lastname: Zimmerman
authors.forename: E P
authors.initials: EP
authors.lastname: Hoberg
authors.forename: L G
authors.initials: LG
authors.lastname: Rickard
authors.forename: J K
authors.initials: JK
authors.lastname: Bishop
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D004341:Drug Evaluation; D005273:Fenbendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D007559:Ivermectin / Q000008:administration & dosage / Q000627:therapeutic use*; D007978:Levamisole / Q000008:administration & dosage / Q000627:therapeutic use*; D009349:Nematode Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000517:prevention & control
chemical_list: D001562:Benzimidazoles; D007978:Levamisole; D005273:Fenbendazole; D007559:Ivermectin