Immunodeficient dwarfism in dogs: a model for neuroimmunomodulation.
This paper discusses the use of dogs as experimental models for neuroimmunomodulation and compares immunodeficient dwarfism in dogs to that in rodents. Immunodeficient dwarfism in dogs is reviewed including description of the clinical syndrome, immunologic characteristics, neuroendocrine abnormalities, thymus histopathology, and therapy.
Roth
J A
JA
Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames 50011.
Goff
B L
BL
Monroe
W E
WE
D000818:Animals; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D004285:Dogs; D004392:Dwarfism / Q000276:immunology / Q000503:physiopathology / Q000662:veterinary*; D013006:Growth Hormone / Q000097:blood; D007153:Immunologic Deficiency Syndromes / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D007167:Immunotherapy; D008213:Lymphocyte Activation; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000473:pathology
D013006:Growth Hormone