title: [Effect of mukodin on indices of mucociliary transport].
abstract: The authors report some data on the assessment of efficacy of mucodin, a modern expectorant. Its effect on the rate of mucociliary transport, rheological properties of sputum was studied in patients with infectious-allergic bronchial asthma. Administration of mucodin improves bronchial clearance promoting normalization of bronchial permeability; a positive time course of viscid-elastic indices of the sputum is noted in comparison with the control group. The drugs make no effect on the adhesive properties of sputum. Probable mechanisms of expectorant action of mucodin are discussed.
authors.forename: V N
authors.initials: VN
authors.lastname: Solopov
authors.forename: I V
authors.initials: IV
authors.lastname: Lunichkina
authors.forename: L F
authors.initials: LF
authors.lastname: Plisko
authors.forename: N A
authors.initials: NA
authors.lastname: Kolganova
mesh_terms: D000268:Adhesiveness; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology; D002233:Carbocysteine / Q000627:therapeutic use*; D003545:Cysteine / Q000031:analogs & derivatives*; D004341:Drug Evaluation; D004548:Elasticity; D006801:Humans; D009079:Mucociliary Clearance / Q000187:drug effects*; D012119:Respiration / Q000187:drug effects; D013183:Sputum / Q000187:drug effects / Q000502:physiology; D013997:Time Factors; D014783:Viscosity
chemical_list: D002233:Carbocysteine; D003545:Cysteine
vernacular_title: Vliianie mukodina na pokazateli mukotsiliarnogo transporta.