title: Effects of prolonged duct ligation of the rat salivary glands on the activity of trypsin-like protease.
abstract: The effects of ligation on body weight, protease activity and hair kynurenine content were observed. The body weights of parotid gland(PT)-ligated and of combined submandibular (SM)-, sublingual (SL)- and PT-ligated rats were much less than those of sham-operated controls. However, the weights of SM,SL-ligated rats were similar to those of controls. The activity of trypsin-like protease in the duct-ligated submandibular gland was significantly reduced to 0.3-0.7 per cent of that in controls. Protein concentration also decreased in the duct-ligated submandibular gland. Kynurenine content in the hair of duct-ligated rats was higher than that in controls.
authors.affiliation: Department of Oral Biochemistry, Tohoku Dental University, Koriyama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ikeno
authors.forename: S
authors.initials: S
authors.lastname: Saikatsu
authors.forename: T
authors.initials: T
authors.lastname: Uno
authors.forename: T
authors.initials: T
authors.lastname: Ikeno
mesh_terms: D000818:Animals; D001835:Body Weight; D006197:Hair / Q000032:analysis; D007737:Kynurenine / Q000032:analysis; D008026:Ligation; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012469:Salivary Glands / Q000201:enzymology / Q000502:physiology* / Q000601:surgery; D013997:Time Factors; D014357:Trypsin / Q000378:metabolism*
chemical_list: D007737:Kynurenine; D014357:Trypsin