Measurement of liver iron content in paraffin-embedded biopsies.
A reliable method for the determination of total liver iron in formalin-fixed, paraffin-embedded tissue is presented. The correlation with total liver iron in fresh tissue is good (r = 0.92). Material, which is processed routinely in the pathological anatomical department and stored in the archives, can be used for a quantitative iron determination for clinical or research purposes.
van Deursen
C
C
Department of Internal Medicine, De Wever-Hospital, Heerlen, The Netherlands.
de Metz
M
M
Koudstaal
J
J
Brombacher
P
P
D001706:Biopsy; D006801:Humans; D007501:Iron / Q000032:analysis*; D008099:Liver / Q000032:analysis* / Q000473:pathology; D010232:Paraffin; D013054:Spectrophotometry, Atomic / Q000379:methods
D010232:Paraffin; D007501:Iron