The characterization of structural variations within a crystal field.
The technique of correlation averaging is refined by the use of multivariate statistical analysis and classification. The refined method can deal with the presence of structural variations within a crystal field. A low-dose image of a crotoxin crystal embedded in ice is used to demonstrate that crystallographic structural parameters characterizing the different areas of such a crystal with varying structure can be extracted rigorously and reproducibly.
Frank
J
J
Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201-0509.
Chiu
W
W
Degn
L
L
D000704:Analysis of Variance; D000818:Animals; D003435:Crotalid Venoms / Q000032:analysis*; D003439:Crotoxin / Q000032:analysis*; D003460:Crystallization; D005583:Fourier Analysis; D007053:Ice; D008854:Microscopy, Electron / Q000379:methods*; D012911:Snakes; D012984:Software; D014961:X-Ray Diffraction
D003435:Crotalid Venoms; D007053:Ice; D003439:Crotoxin