Concanavalin A interacts with lysozyme: a model for understanding lectin--glycoprotein interactions.
Lysozyme, a well-characterized protein which is known to be devoid of any carbohydrate residues, was found to interact with Con A. This interaction could be inhibited by high salt concentration or ethylene glycol or specific sugars. These results indicate that the protein part of glycoproteins may play an important role in lectin-glycoprotein interactions.
Vaidya
S
S
Department of Chemistry, Indian Institute of Technology, New Delhi.
Gupta
M N
MN
D000818:Animals; D002645:Chickens; D003208:Concanavalin A / Q000378:metabolism*; D005026:Ethylene Glycols / Q000494:pharmacology; D005690:Galactose / Q000494:pharmacology; D006023:Glycoproteins / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D007785:Lactose / Q000494:pharmacology; D037102:Lectins / Q000378:metabolism*; D008954:Models, Biological; D009113:Muramidase / Q000378:metabolism*; D012965:Sodium Chloride / Q000494:pharmacology; D013696:Temperature
D005026:Ethylene Glycols; D006023:Glycoproteins; D037102:Lectins; D003208:Concanavalin A; D012965:Sodium Chloride; D009113:Muramidase; D007785:Lactose; D005690:Galactose