title: Variation in the hemolytic activity of Leptospira interrogans serovar canicola.
abstract: Leptospira interrogans serovar canicola strain moulton was grown to a high cell density in a protein-free medium with hemin. The hemolysin produced in this culture system showed a greatly expanded spectrum of hemolysis as compared to previous reports of leptospiral hemolysin produced in a more traditional culture system containing serum.
authors.affiliation: Department of Medical Microbiology, University of Nebraska College of Medicine, Omaha 68105.
authors.forename: E M
authors.initials: EM
authors.lastname: Lane
authors.forename: R F
authors.initials: RF
authors.lastname: Ramaley
authors.forename: N G
authors.initials: NG
authors.lastname: Miller
mesh_terms: D000818:Animals; D006224:Cricetinae; D003470:Culture Media; D004285:Dogs; D006168:Guinea Pigs; D006460:Hemolysin Proteins / Q000096:biosynthesis / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D007921:Leptospira interrogans / Q000378:metabolism*; D051379:Mice; D011817:Rabbits
chemical_list: D003470:Culture Media; D006460:Hemolysin Proteins