title: Syndromes of Vibrio vulnificus infections. Clinical and epidemiologic features in Florida cases, 1981-1987.
abstract: OBJECTIVE
  To describe the clinical and epidemiologic features of Vibrio vulnificus infections.
  
  
  METHODS
  Case series based on notifiable disease report forms and patient medical records.
  
  
  METHODS
  Cases reported to the Florida Department of Health and Rehabilitative Services from 1981 to 1987.
  
  
  METHODS
  Sixty-two patients with V. vulnificus infection.
  
  
  RESULTS
  The three clinical syndromes found were primary septicemia (38 patients), wound infections (17 patients), and gastrointestinal illness without septicemia or wound infections (7 patients). Mortality rate was highest for patients with primary septicemia (55%; 95% CI, 38 to 71) and intermediate for wound infections (24%; 95% CI, 8 to 51): no deaths occurred in those with gastrointestinal illness. Common characteristics and exposures in patients with these syndromes included recent history of raw oyster consumption for primary septicemia and gastrointestinal illness, liver disease for primary septicemia, and either having a preexisting wound or sustaining a wound in contact with seawater for wound infections.
  
  
  CONCLUSIONS
  Clinicians should ask about marine exposures in patients with underlying medical conditions, especially liver disease, who present with unexplained febrile illness, and should start appropriate therapy promptly.
authors.affiliation: Centers for Disease Control, Atlanta, Georgia.
authors.forename: K C
authors.initials: KC
authors.lastname: Klontz
authors.forename: S
authors.initials: S
authors.lastname: Lieb
authors.forename: M
authors.initials: M
authors.lastname: Schreiber
authors.forename: H T
authors.initials: HT
authors.lastname: Janowski
authors.forename: L M
authors.initials: LM
authors.lastname: Baldy
authors.forename: R A
authors.initials: RA
authors.lastname: Gunn
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D004196:Disease Outbreaks; D004812:Epidemiologic Methods; D005260:Female; D005431:Florida; D005759:Gastroenteritis / Q000382:microbiology; D006801:Humans; D008107:Liver Diseases / Q000150:complications; D008297:Male; D008875:Middle Aged; D010125:Ostreidae / Q000382:microbiology; D012623:Seawater; D018805:Sepsis / Q000382:microbiology / Q000401:mortality; D014733:Vibrio; D014735:Vibrio Infections / Q000453:epidemiology / Q000401:mortality; D014871:Water Microbiology; D014946:Wound Infection / Q000382:microbiology