[Restoration of immune status by interleukin 2?].
Beyond a donor age (a) of 22 years, the DNA incision ability in human peripheral lymphocytes was found to decrease according to 1/a2.5. Other lymphocyte functions linked to the differentiation program may follow this age-dependency. First results show that interleukin-2 is able to compensate, at least partly, the age-dependent deficiency of immune response.
Hartwig
M
M
Zentralinstitut für Molekularbiologie, Akademie der Wissenschaften der DDR.
D000368:Aged; D004249:DNA Damage; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000628:therapy*; D007376:Interleukin-2 / Q000627:therapeutic use*; D008213:Lymphocyte Activation / Q000187:drug effects; D011379:Prognosis; D011994:Recombinant Proteins / Q000627:therapeutic use
D007376:Interleukin-2; D011994:Recombinant Proteins
Restauration des Immunstatus durch Interleukin-2?