[Versatility of arterial and venous responses to the action of physiologic stimuli in rats with DOCA-salt hypertension].
The reactivity of the rat popliteal, mesenteric and renal arteries and veins to electrical stimulation, noradrenaline, serotonin and potassium chloride in the DOCA-salt hypertension, was studied. The data obtained reveal the organ heterogeneity of the blood vessels contractile responses and the changes of arterial and venous responses in the hypertension, the character and extent of these changes depending on a particular vascular bed and the type of stimulation. Functional changes in hypertensive veins were stronger than in arteries. The artery and vein contractile responses were found to be associated with the external calcium altered in the hypertension. A direct influence of the DOCA and the salt overload on vascular reactivity was studied as well.
Govyrin
V A
VA
Leont'eva
G R
GR
Elinek
I
I
Zikha
I
I
Kunesh
Ia
Ia
D000818:Animals; D003900:Desoxycorticosterone / Q000633:toxicity*; D004558:Electric Stimulation; D006973:Hypertension / Q000139:chemically induced / Q000503:physiopathology*; D007668:Kidney / Q000098:blood supply* / Q000503:physiopathology; D008297:Male; D008638:Mesenteric Arteries / Q000503:physiopathology; D008642:Mesenteric Veins / Q000503:physiopathology; D009119:Muscle Contraction; D009131:Muscle, Smooth, Vascular; D009392:Nephrectomy; D009638:Norepinephrine / Q000502:physiology; D011150:Popliteal Artery / Q000503:physiopathology; D011152:Popliteal Vein / Q000503:physiopathology; D011189:Potassium Chloride / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012077:Renal Artery / Q000503:physiopathology; D012082:Renal Veins / Q000503:physiopathology; D012701:Serotonin / Q000502:physiology; D012965:Sodium Chloride / Q000633:toxicity*
D012701:Serotonin; D003900:Desoxycorticosterone; D012965:Sodium Chloride; D011189:Potassium Chloride; D009638:Norepinephrine
Mnogoobrazie reaktsiĭ arteriĭ i ven na deĭstvie fiziologicheskikh stimulov u krys s DOKA-solevoĭ gipertenzieĭ.