Does high cortisol in uremic patients influence their glucagon levels?
In view of the data reported by Barseghian and Levine (1980) that cortisol exerts a direct stimulatory influence on glucagon secretion, the relationship between plasma cortisol and glucagon levels in a group of 43 patients with chronic renal failure (CRF) was investigated. A positive correlation (r = 0.363 and 0.811) was found with all patients studied or with 10 patients with urine output above 1000 ml/24 h, respectively. The result obtained suggest that the elevated cortisol levels play some role in the stimulation of glucagon secretion in CRF patients.
Ivić
M A
MA
Institute of Nephrology, Faculty of Medicine, Nis, Yugoslavia.
Stefanović
V
V
D005934:Glucagon / Q000097:blood* / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000503:physiopathology; D006435:Renal Dialysis
D005934:Glucagon; D006854:Hydrocortisone