title: [Disorders of myocardial perfusion in Kawasaki syndrome: noninvasive detection by 201 thallium tomography].
abstract: Myocardial infarction and stenotic coronary lesions are serious late complications in children with Kawasaki disease. For the noninvasive assessment of myocardial perfusion, dipyridamole-redistribution thallium-201 emission computed tomography (ECT) was performed in seven children (aged from 2 8/12 to 8 7/12 years) 3 to 20 months after the acute stage of the disease. In all patients, coronary aneurysms had been demonstrated by cross-sectional echocardiography. The scintigrams of six children showed no significant regional reduction of myocardial thallium-201 uptake. These children had remained asymptomatic since the acute stage of Kawasaki disease. Persistent and transient thallium-201 defects were present in one child with documented myocardial infarction. For this patient, obstructions of corresponding coronary vessels were confirmed by contrast angiography. It is suggested that thallium-201 ECT with dipyridamole-induced vasodilatation may be used as a safe alternative to invasive coronary angiography for detection of ischemia and follow-up investigations in patients with Kawasaki disease.
authors.affiliation: UCLA School of Medicine, Dept. of Radiological Sciences.
authors.forename: C A
authors.initials: CA
authors.lastname: Nienaber
authors.forename: G
authors.initials: G
authors.lastname: Hausdorf
authors.forename: R P
authors.initials: RP
authors.lastname: Spielmann
mesh_terms: D002648:Child; D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging*; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000000981:diagnostic imaging*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging; D013794:Thallium Radioisotopes; D014055:Tomography, Emission-Computed
chemical_list: D013794:Thallium Radioisotopes
vernacular_title: Myokardiale Perfusionsstörungen bei Kawasaki-Syndrom: nichtinvasiver Nachweis durch 201-Thallium-Tomographie.