Venom immunotherapy during pregnancy.
A patient who received venom immunotherapy during pregnancy without complications delivered a healthy term infant. Venom-specific IgG antibodies were similar in the mother and infant at birth and then fell to undetectable levels by six months of age. Although the mother had elevated venom-specific IgE levels, they were not detectable in the infant at birth or six months of age. Therefore, venom immunotherapy during pregnancy did not lead to allergic sensitization of this child.
Graft
D F
DF
University of Minnesota School of Medicine, Minneapolis 55416.
D000328:Adult; D001514:Bee Venoms / Q000276:immunology*; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007167:Immunotherapy; D007223:Infant; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014862:Wasp Venoms / Q000276:immunology*
D001514:Bee Venoms; D007074:Immunoglobulin G; D014862:Wasp Venoms; D007073:Immunoglobulin E