title: A long-term follow-up case study of crossed aphasia assessed by single-photon emission tomography (SPECT), language, and neuropsychological testing.
abstract: A 65-year-old man with well-defined crossed aphasia secondary to right cerebral infarction 10 years previously was studied for current language and cognitive abilities and regional cerebral blood flow (rCBF) during cognitive activation measured by single-photon emission tomography (SPECT). Reversed hemispheric lateralization was demonstrated by qualitative aspects of the patient's constructional deficits, dominant parietal lobe signs, and absence of the neglect syndrome. Language activation procedures during SPECT produced focal increases in rCBF to both frontal lobes with a phoneme detection task and to right temporal and parietal lobes with a math task. The authors stress the complexities of assessing brain/language mechanisms in vivo and demonstrate variabilities in rCBF during language activation dependent on task selection.
authors.affiliation: Department of Communication Sciences, Texas Woman's University, Denton 76204.
authors.forename: D
authors.initials: D
authors.lastname: Walker-Batson
authors.forename: J S
authors.initials: JS
authors.lastname: Wendt
authors.forename: M D
authors.initials: MD
authors.lastname: Devous
authors.forename: M M
authors.initials: MM
authors.lastname: Barton
authors.forename: F J
authors.initials: FJ
authors.lastname: Bonte
mesh_terms: D000368:Aged; D001037:Aphasia / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D003071:Cognition / Q000502:physiology*; D005625:Frontal Lobe / Q000098:blood supply; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D007802:Language; D008433:Mathematics; D009778:Occipital Lobe / Q000098:blood supply; D010296:Parietal Lobe / Q000098:blood supply; D010700:Phonetics; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed; D014888:Wechsler Scales