[Long-term study of patients with active chronic hepatitis treated with leukocyte interferon].
Seven patients with active chronic hepatitis who received Interferon Alfa showed a marked humoral and histological improvement one year after the treatment was concluded, in 3 patients the hepatic histology was almost normal, 2 evolved to a persistent chronic hepatitis and only one showed deterioration. These results differed from those obtained immediately after the treatment (p 0.05). Interferon Alfa proves to be of the most usefulness in this disease, studies should be continued up to one year after the treatment has ended.
Sotto
A
A
Instituto de Gastroenterología, La Habana, Cuba.
Selman
E
E
Grá
B
B
Arencibia
I
I
Morales
M
M
Llanio
R
R
D005500:Follow-Up Studies; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006521:Hepatitis, Chronic / Q000276:immunology / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D014779:Virus Replication / Q000187:drug effects
D006514:Hepatitis B Surface Antigens; D007370:Interferon Type I
Estudio a largo plazo de pacientes con hepatitis crónica activa tratados con interferón leucocitario.