[The nature of nonspecific reactions in designing erythrocyte diagnostic agents for determining the HBs antigen].
The nature of nonspecific reactions observed in reverse passive hemagglutination test was studied. Nonspecific reactions were found to be associated with the use of different ingredients in construction of immunodiagnostic preparations for HBs antigen and with the presence in the examined sera of heterologous hemagglutinins, rheumatoid factor, and bacterial contamination. Therefore, positive results of hemagglutination should be verified for specificity by neutralization tests with HBs antigen.
Leshchuk
S I
SI
D000818:Animals; D000918:Antibody Specificity; D002645:Chickens / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D005069:Evaluation Studies as Topic; D005260:Female; D006041:Goats / Q000276:immunology; D006386:Hemagglutination Tests / Q000379:methods; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D007113:Immunity, Innate; D009500:Neutralization Tests; D014422:Turkeys / Q000276:immunology
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens
Izuchenie prirody nekotorykh nespetsificheskikh reaktsiĭ pri konstruirovanii éritrotsitarnykh diagnostikumov dlia opredeleniia HBs-antigena.