Physiological mechanism of digital vasoconstriction training.
Recent work in our laboratory has shown that vasodilation produced during temperature biofeedback training is mediated through a nonneural, beta-adrenergic mechanism. Here we sought to determine if the effects of feedback training for vasoconstriction are produced through a neural or nonneural pathway and whether other measures of physiological activity are correlated with these changes. Nine normal subjects received temperature feedback vasoconstriction training in which feedback was delivered only during periods of successful performance. In a subsequent session, the nerves to one finger were blocked with a local anesthetic while finger blood flow was recorded from this and other fingers. Vasoconstriction occurred during feedback in the intact fingers but not in the nerve-blocked finger and was accompanied by increased skin conductance and heart rate. These data demonstrate that temperature feedback vasoconstriction training is mediated through an efferent, sympathetic nervous pathway. In contrast, temperature feedback vasodilation training is mediated through a nonneural, beta-adrenergic mechanism.
Freedman
R R
RR
Lafayette Clinic, Detroit, Michigan 48207.
Morris
M
M
Norton
D A
DA
Masselink
D
D
Sabharwal
S C
SC
Mayes
M
M
D000328:Adult; D001340:Autonomic Nerve Block; D001676:Biofeedback, Psychology / Q000502:physiology*; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D008297:Male; D010865:Pilot Projects; D013564:Sympathetic Nervous System / Q000502:physiology; D014661:Vasoconstriction