[Effect of mukodin on indices of mucociliary transport].
The authors report some data on the assessment of efficacy of mucodin, a modern expectorant. Its effect on the rate of mucociliary transport, rheological properties of sputum was studied in patients with infectious-allergic bronchial asthma. Administration of mucodin improves bronchial clearance promoting normalization of bronchial permeability; a positive time course of viscid-elastic indices of the sputum is noted in comparison with the control group. The drugs make no effect on the adhesive properties of sputum. Probable mechanisms of expectorant action of mucodin are discussed.
Solopov
V N
VN
Lunichkina
I V
IV
Plisko
L F
LF
Kolganova
N A
NA
D000268:Adhesiveness; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology; D002233:Carbocysteine / Q000627:therapeutic use*; D003545:Cysteine / Q000031:analogs & derivatives*; D004341:Drug Evaluation; D004548:Elasticity; D006801:Humans; D009079:Mucociliary Clearance / Q000187:drug effects*; D012119:Respiration / Q000187:drug effects; D013183:Sputum / Q000187:drug effects / Q000502:physiology; D013997:Time Factors; D014783:Viscosity
D002233:Carbocysteine; D003545:Cysteine
Vliianie mukodina na pokazateli mukotsiliarnogo transporta.