title: [Influence of temperature on the function of the human testes].
abstract: The influence of temperature on human Leydig and Sertoli cell functions was investigated in vitro using the organ culture technique. Specific 125I-FSH and 125I-hCG binding sites in testes from patients with prostate cancer cultured for 1, 3, 5 or 7 days at 33 degrees C or 37 degrees C were measured and compared. There were no significant differences in 125I-FSH or 125I-hCG binding sites between the two temperature groups at 1 to 7 days of culture. Testosterone concentration in the medium obtained from testicular organ culture at 33 degrees C did not differ significantly from that at 37 degrees C at 1 to 7 days of culture. In conclusion, a high temperature may not disturb the Leydig and Sertoli cell functions in a short term.
authors.affiliation: Department of Urology, Osaka Central Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Namiki
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: A
authors.initials: A
authors.lastname: Okuyama
authors.forename: Y
authors.initials: Y
authors.lastname: Doi
authors.forename: T
authors.initials: T
authors.lastname: Matsui
authors.forename: H
authors.initials: H
authors.lastname: Fujisue
authors.forename: M
authors.initials: M
authors.lastname: Takeyama
authors.forename: H
authors.initials: H
authors.lastname: Fujioka
mesh_terms: D000368:Aged; D006063:Chorionic Gonadotropin / Q000378:metabolism; D006801:Humans; D007985:Leydig Cells / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009924:Organ Culture Techniques; D012708:Sertoli Cells / Q000502:physiology; D013696:Temperature; D013737:Testis / Q000378:metabolism / Q000502:physiology*
chemical_list: D006063:Chorionic Gonadotropin