A photoaffinity label for the D-1 dopamine receptor, (RS)-7-[125I]Iodo-8-hydroxy-3-methyl-1-(4'-azidophenyl)-2,3,4,5- tetrahydro-1H-3-benzazepine, selectively identifies the ligand binding subunits of the receptor.
Baindur
N
N
Section of Medicinal Chemistry, College of Pharmacy and Allied Health Professions, Northeastern University, Boston, Massachusetts 02115.
Neumeyer
J L
JL
Niznik
H B
HB
Bzowej
N H
NH
Jarvie
K R
KR
Seeman
P
P
Garlick
R K
RK
Miller
J J
JJ
D015647:2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; D000345:Affinity Labels; D000818:Animals; D001552:Benzazepines; D001665:Binding Sites; D001667:Binding, Competitive; D001923:Brain Chemistry; D004285:Dogs; D010777:Photochemistry; D011954:Receptors, Dopamine / Q000032:analysis*
D000345:Affinity Labels; D001552:Benzazepines; D011954:Receptors, Dopamine; D015647:2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine