title: Positron emission tomography in a patient with progressive multifocal leukoencephalopathy.
abstract: A 56-year-old man with chronic lymphocytic leukemia, progressive multifocal leukoencephalopathy, and a dense left homonymous hemianopia had 18F-fluorodeoxyglucose positron emission tomography. Cortical glucose metabolism was decreased in the right cerebral hemisphere and the left cerebellar hemisphere. To our knowledge, this is the first demonstration of cerebral and cerebellar hypometabolism due solely to white matter disease.
authors.affiliation: Department of Neurology, University of Pennsylvania, Philadelphia.
authors.forename: M
authors.initials: M
authors.lastname: Kiyosawa
authors.forename: T M
authors.initials: TM
authors.lastname: Bosley
authors.forename: A
authors.initials: A
authors.lastname: Alavi
authors.forename: N
authors.initials: N
authors.lastname: Gupta
authors.forename: C H
authors.initials: CH
authors.lastname: Rhodes
authors.forename: J
authors.initials: J
authors.lastname: Chawluk
authors.forename: M
authors.initials: M
authors.lastname: Kushner
authors.forename: P J
authors.initials: PJ
authors.lastname: Savino
authors.forename: R C
authors.initials: RC
authors.lastname: Sergott
authors.forename: N J
authors.initials: NJ
authors.lastname: Schatz
mesh_terms: D000368:Aged; D001921:Brain / Q000378:metabolism / Q000473:pathology; D003847:Deoxyglucose / Q000031:analogs & derivatives / Q000378:metabolism; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism; D006423:Hemianopsia / Q000150:complications; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D014018:Tissue Distribution; D014055:Tomography, Emission-Computed
chemical_list: D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D005947:Glucose