t(1;19) and t(12;17) in childhood acute lymphoblastic leukemia of pre-B type.
We report on a patient with pre-B acute lymphoblastic leukemia (ALL) and t(t;19) as the principal chromosomal abnormality. The presence of the subsequent t(12;17) and the correlation between the chromosomal anomalies and the immunologic phenotype is discussed.
Ghione
F
F
Sezione di Ematologia, Clinica Pediatrica III, Universita degli Studi di Firenze, Firenze, Italy.
Gargano
D
D
Guazzelli
C
C
Lippi
A
A
D001402:B-Lymphocytes; D002675:Child, Preschool; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002881:Chromosomes, Human, Pair 12; D002886:Chromosomes, Human, Pair 17; D002888:Chromosomes, Human, Pair 19; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic