Murine mRNA for the beta-subunit of integrin is increased in BALB/c-3T3 cells entering the G1 phase from the G0 state.
The amount of murine mRNA for the beta-subunit of integrin is enriched 6-fold when BALB/c-3T3 cells traverse from the G0 state to the G1 phase, whereas it remains at the basal level when the cells are growing continuously. The peak of its appearance is at 10 h after serum stimulation. The increase in integrin mRNA at a specific point in cell proliferation may be correlated with growth-signal transduction.
Tominaga
S
S
Okinaka Memorial Institute for Medical Research, Tokyo, Japan.
D000595:Amino Acid Sequence; D000818:Animals; D000954:Antigens, Surface; D001483:Base Sequence; D002455:Cell Division; D002460:Cell Line; D004247:DNA / Q000235:genetics; D016023:Integrins; D007399:Interphase; D007700:Kinetics; D008562:Membrane Glycoproteins / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000378:metabolism*; D011971:Receptors, Immunologic; D015398:Signal Transduction
D000954:Antigens, Surface; D016023:Integrins; D008562:Membrane Glycoproteins; D012333:RNA, Messenger; D011971:Receptors, Immunologic; D004247:DNA