Parenteral aztreonam in the treatment of Haemophilus influenzae type b meningitis in Egyptian children.
13 children, 8 girls and 5 boys, aged 2-15 months (mean 8.5 months), with Haemophilus influenzae meningitis were treated with aztreonam. Aztreonam was administered intramuscularly in a dose of 50 mg/kg every 8 h. 10 of the infants were in coma and 3 were drowsy when first examined in hospital. All except 2 infants, who were in coma and who died within 24 h of starting therapy, recovered quickly. All patients became fully alert within 4-5 days and afebrile within 5 to 6 days.
Girgis
N I
NI
US Naval Medical Research Unit No. 3, Cairo, Egypt.
Abu el Ella
A H
AH
Farid
Z
Z
Woody
J N
JN
Haberberger
R L
RL
el Messidy
M
M
Dessouky
A
A
D001398:Aztreonam / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006193:Haemophilus influenzae; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D008297:Male; D008583:Meningitis, Haemophilus / Q000134:cerebrospinal fluid / Q000188:drug therapy*
D001398:Aztreonam