Positron emission tomography in a patient with progressive multifocal leukoencephalopathy.
A 56-year-old man with chronic lymphocytic leukemia, progressive multifocal leukoencephalopathy, and a dense left homonymous hemianopia had 18F-fluorodeoxyglucose positron emission tomography. Cortical glucose metabolism was decreased in the right cerebral hemisphere and the left cerebellar hemisphere. To our knowledge, this is the first demonstration of cerebral and cerebellar hypometabolism due solely to white matter disease.
Kiyosawa
M
M
Department of Neurology, University of Pennsylvania, Philadelphia.
Bosley
T M
TM
Alavi
A
A
Gupta
N
N
Rhodes
C H
CH
Chawluk
J
J
Kushner
M
M
Savino
P J
PJ
Sergott
R C
RC
Schatz
N J
NJ
D000368:Aged; D001921:Brain / Q000378:metabolism / Q000473:pathology; D003847:Deoxyglucose / Q000031:analogs & derivatives / Q000378:metabolism; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism; D006423:Hemianopsia / Q000150:complications; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D014018:Tissue Distribution; D014055:Tomography, Emission-Computed
D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D005947:Glucose