In vitro susceptibility of Trichomonas vaginalis to 50 antimicrobial agents.
We determined the susceptibilities of five strains of Trichomonas vaginalis, one of which was metronidazole resistant, to 50 antimicrobial agents. For the metronidazole-susceptible strains, the most active agents were metronidazole, tinidazole, mebendazole, furazolidone, and anisomycin. Against the resistant strain mebendazole, furazolidone, and anisomycin were the most active. Antifungal agents, beta-lactams, macrolides, aminoglycosides, and folic acid antagonists were ineffective against all strains.
Sears
S D
SD
Department of Medicine, Wyman Park Health System, Baltimore, Maryland 21211.
O'Hare
J
J
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D000981:Antiprotozoal Agents / Q000494:pharmacology; D004351:Drug Resistance; D005493:Folic Acid Antagonists / Q000494:pharmacology; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D014246:Trichomonas vaginalis / Q000187:drug effects*
D000871:Anthelmintics; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000981:Antiprotozoal Agents; D005493:Folic Acid Antagonists; D008795:Metronidazole