title: [Accumulation velocity of 99mTc-HMDP in hip joint diseases].
abstract: The accumulation rate and velocity of 99mTc-hydroxymethylene diphosphonate (99mTc-HMDP) in hip joints were determined within four minutes after a bolus of injection of 99mTc-HMDP in the patients with hip joint disorders. There exist a significant relationship between accumulation velocity of 99mTc-HMDP in the affected joint and serum osteocalcin in the patients with eight cases of degenerative osteoarthropathy and six cases of femoral necrosis. This result indicates that the accumulation velocity of 99mTc-HMDP in the affected joint is likely to become a marker of bone turnover in hip joint disorder.
authors.affiliation: Department of Radiology, Wakayama Medical College, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Torizumi
authors.forename: H
authors.initials: H
authors.lastname: Aibata
authors.forename: S
authors.initials: S
authors.lastname: Kiji
authors.forename: A
authors.initials: A
authors.lastname: Ueyoshi
authors.forename: Y
authors.initials: Y
authors.lastname: Kiura
authors.forename: Y
authors.initials: Y
authors.lastname: Okamoto
authors.forename: T
authors.initials: T
authors.lastname: Tuda
authors.forename: K
authors.initials: K
authors.lastname: Ota
mesh_terms: D000328:Adult; D000368:Aged; D002135:Calcium-Binding Proteins / Q000097:blood; D005260:Female; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging* / Q000378:metabolism; D006621:Hip Joint / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging* / Q000378:metabolism; D015675:Osteocalcin; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives* / Q000493:pharmacokinetics
chemical_list: D002135:Calcium-Binding Proteins; D015675:Osteocalcin; C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate