title: Changes in sulfhydryl compounds in plasma, liver and brain after acute and chronic acetaldehyde administration in rats.
abstract: The content of sulfhydryl compounds in proteins and non-proteins of plasma, liver and brain after acute and chronic administration of acetaldehyde (ACH) was investigated in rats. After ACH 1.5% w/v ingestion for 1 and 4 weeks (0.3 ml/kg) daily, proteins and non-proteins in plasma and liver were decreased significantly. After acute ACH administration SH-groups in brain proteins were not significantly decreased, but in the brain non-proteins these groups were increased significantly.
authors.affiliation: Department of Inorganic and Analytical Chemistry, Medical Academy, Białystok, Poland.
authors.forename: R
authors.initials: R
authors.lastname: Farbiszewski
authors.forename: M
authors.initials: M
authors.lastname: Chwiećko
authors.forename: A
authors.initials: A
authors.lastname: Hołownia
authors.forename: M
authors.initials: M
authors.lastname: Brzozowski
mesh_terms: D000079:Acetaldehyde / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008099:Liver / Q000187:drug effects*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013438:Sulfhydryl Compounds / Q000097:blood*
chemical_list: D013438:Sulfhydryl Compounds; D000079:Acetaldehyde