title: Blindness from misuse of over-the-counter eye medications.
abstract: Blindness from misuse of over-the-counter (OTC) eye drop preparations is reported. This is a previously unreported category of visual loss. Four eyes were blinded in three patients who used OTC preparations when they suffered angle-closure glaucoma. Another eye suffered a reduction in vision from 20/20 to 20/200 when the patient treated a subluxed lens implant with OTC preparations for three months. The motivating factors for self treatment by individuals are discussed. These include advertising, lack of education, and a desire to reduce the cost of health care. Since the common OTC eye drops contain alpha-receptor stimulators, it is possible that they may either augment existing mydriasis or precipitate it if used in excessive amounts. It is difficult to estimate the number of cases of blindness from misuse of OTC eye drops. Education of the public about the dangers of self diagnosis and treatment of health problems including the red eye is necessary.
authors.affiliation: Department of Ophthalmology, Washington University, St. Louis, Missouri.
authors.forename: M B
authors.initials: MB
authors.lastname: Rumelt
mesh_terms: D000208:Acute Disease; D000368:Aged; D001766:Blindness / Q000139:chemically induced*; D002387:Cataract Extraction / Q000009:adverse effects; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology; D005260:Female; D005901:Glaucoma / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D004366:Nonprescription Drugs / Q000009:adverse effects* / Q000627:therapeutic use; D009883:Ophthalmic Solutions
chemical_list: D004366:Nonprescription Drugs; D009883:Ophthalmic Solutions