title: Propofol in elderly high risk patients. A comparison of haemodynamic effects with thiopentone during induction of anaesthesia.
abstract: Twenty elderly patients of ASA grade 3 or 4, received either propofol 1 mg/kg or thiopentone 2 mg/kg for induction of anaesthesia. These doses provided a convenient level of anaesthesia for all patients. There were no significant intra- or intergroup haemodynamic changes, with the exception of a decrease in diastolic pressure and rate-pressure product after propofol. It is concluded that propofol 1 mg/kg can be used to induce anaesthesia in elderly high risk patients without deleterious cardiovascular effects.
authors.affiliation: Service d'Anesthésie, Hôpital de Hautepierre, Strasbourg, France.
authors.forename: A
authors.initials: A
authors.lastname: Steib
authors.forename: G
authors.initials: G
authors.lastname: Freys
authors.forename: J P
authors.initials: JP
authors.lastname: Beller
authors.forename: U
authors.initials: U
authors.lastname: Curzola
authors.forename: J C
authors.initials: JC
authors.lastname: Otteni
mesh_terms: D000368:Aged; D000771:Anesthesia, Intravenous; D000777:Anesthetics / Q000494:pharmacology*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D010636:Phenols / Q000494:pharmacology*; D015742:Propofol; D011446:Prospective Studies; D012307:Risk Factors; D013874:Thiopental / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000777:Anesthetics; D010636:Phenols; D013874:Thiopental; D015742:Propofol