title: Beta-lactamase-producing bacteria in head and neck infection.
abstract: We have summarized our experience in recovery of beta-lactamase-producing bacteria (BLPB) in head and neck infection (HNI). These HNI include conjunctivitis, serous and chronic otitis media, cholesteatoma, chronic mastoiditis, chronic sinusitis, adenoiditis, recurrent tonsillitis in children and adults, peritonsillar abscess, and retropharyngeal abscess. Beta-lactamase-producing bacteria were found in 262 (51%) of 513 patients with HNI; 72% had aerobic BLPB and 57% had anaerobic BLPB. The infections, where these organisms were most frequently recovered, were adenoiditis (85% of patients), tonsillitis in adults (82%) and children (74%), retropharyngeal abscess (71%), and chronic otitis media (57%). The predominant BLPB were Staphylococcus aureus (49% of patients with BLPB), the Bacteroides-melaninogenicus group (28%), the Bacteroides fragilis group (20%), Pseudomonas aeruginosa (13%), Hemophilus influenzae (5%), and Branhamella catarrhalis (3%). The high incidence of recovery of BLPB in head and neck infections may have important implications on the antimicrobial management of these infections.
authors.affiliation: Department of Pediatrics and Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD.
authors.forename: I
authors.initials: I
authors.lastname: Brook
mesh_terms: D001424:Bacterial Infections / Q000175:diagnosis*; D001442:Bacteroides Infections / Q000175:diagnosis; D002648:Child; D002781:Cholesteatoma / Q000209:etiology*; D003231:Conjunctivitis / Q000209:etiology*; D004427:Ear Diseases / Q000209:etiology*; D006192:Haemophilus Infections / Q000175:diagnosis; D006801:Humans; D010608:Pharyngeal Diseases / Q000209:etiology*; D011552:Pseudomonas Infections / Q000175:diagnosis; D012852:Sinusitis / Q000209:etiology*; D013203:Staphylococcal Infections / Q000175:diagnosis; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases