title: Distribution of 10-formyltetrahydrofolate synthetase in eubacteria.
abstract: The distribution of 10-formyltetrahydrofolate synthetase, which activates formate for use as a one-carbon donor in a variety of biosynthetic reactions, was determined for a variety of eubacteria. Organisms from several genera were found to lack detectable synthetase activity; however, all organisms tested were found to contain 5,10-methylenetetrahydrofolate dehydrogenase activity.
authors.affiliation: Department of Biochemistry, University of California, Berkeley 94720.
authors.forename: T R
authors.initials: TR
authors.lastname: Whitehead
authors.forename: M
authors.initials: M
authors.lastname: Park
authors.forename: J C
authors.initials: JC
authors.lastname: Rabinowitz
mesh_terms: D001419:Bacteria / Q000201:enzymology*; D005574:Formate-Tetrahydrofolate Ligase / Q000378:metabolism*; D005561:Formates / Q000378:metabolism; D008025:Ligases / Q000378:metabolism*; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP) / Q000378:metabolism
chemical_list: D005561:Formates; D008754:Methylenetetrahydrofolate Dehydrogenase (NADP); D008025:Ligases; D005574:Formate-Tetrahydrofolate Ligase