title: Epidemiological aspects of leptospirosis in a slum area in the city of Rio de Janeiro, Brazil. Search for leptospires and specific antibodies in rodents.
abstract: 101 Rattus norvegicus and 3 Mus musculus were captured in an urban slum of Rio de Janeiro city and examined for leptospiral infection. Direct examination of urine, serology (microagglutination) and culture together gave a positivity rate of 39%. Separately direct examination and serology gave positivity rates of 13% and 36% respectively. Serogroup Icterohaemorrhagiae predominated in the serological tests. Leptospires were isolated from 24 of the 104 rodents (23%), but 4 cultures died. The remaining 20 were identified as members of the Icterohaemorrhagiae serogroup, and 5 were further identified as serovar copenhageni. Human leptospiral infection, mainly caused by Icterohaemorrhagiae, is endemic in Rio de Janeiro city, and rodents are a major source of the disease.
authors.affiliation: Department of Bacteriology, Fundação Oswasldo Cruz, Rio de Janeiro, Brazil.
authors.forename: M M
authors.initials: MM
authors.lastname: Pereira
authors.forename: J
authors.initials: J
authors.lastname: Andrade
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D001938:Brazil; D005260:Female; D007919:Leptospira / Q000276:immunology*; D007922:Leptospirosis / Q000453:epidemiology* / Q000635:transmission; D008297:Male; D009115:Muridae / Q000382:microbiology*; D011204:Poverty Areas; D051381:Rats / Q000382:microbiology*
chemical_list: D000907:Antibodies, Bacterial