title: [Clinical study of S 6472 granule preparation (sustained-release cefaclor) in chronic respiratory airway infections].
abstract: S 6472 granule preparation, a sustained-release preparation of cefaclor, was administered to 21 patients with chronic respiratory airway infections for its clinical study; a daily dosage between 750 and 1,500 mg was orally given in 2 divided doses after breakfast and dinner for a duration of 3 to 14 days. Clinical effects were good in 15 cases, fair in 1 case, poor in 4 cases and unknown in 1 case. No side effects were observed except for a case of impaired appetite. There appeared to be no abnormal laboratory test valued due to the drug.
authors.affiliation: Department of Respiratory Diseases, Kanagawa Prefectural Nagahama Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Odagiri
authors.forename: K
authors.initials: K
authors.lastname: Matsunaga
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Murohashi
authors.forename: H
authors.initials: H
authors.lastname: Numata
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: I
authors.initials: I
authors.lastname: Yamaki
authors.forename: S
authors.initials: S
authors.lastname: Ishii
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002433:Cefaclor / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002506:Cephalexin / Q000031:analogs & derivatives*; D002908:Chronic Disease; D003692:Delayed-Action Preparations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D003692:Delayed-Action Preparations; D002433:Cefaclor; D002506:Cephalexin