title: Effective pulmonary blood flow in normal children at rest.
abstract: Effective pulmonary blood flow was measured with a soluble inert gas uptake method (10% argon, 3.5% freon-22, 35% oxygen, balance nitrogen) in 98 apparently healthy children aged 5-14 years. None had any evidence of cardiorespiratory disease and all had normal values for absolute and dynamic lung volumes and transfer factor for carbon monoxide. Values of blood flow measured by a rebreathing method correlated reasonably closely with height, weight, body surface area, and lung volumes, and to a lesser extent with hand and foot size. The mean (SD) effective pulmonary blood flow index was 2.7 (0.31) 1 min-1 m-2. Small children found a single breath method of measuring flow more difficult to perform and the results were more variable.
authors.affiliation: Department of Clinical Physiology, Brompton Hospital, London.
authors.forename: J J
authors.initials: JJ
authors.lastname: Bowyer
authors.forename: J O
authors.initials: JO
authors.lastname: Warner
authors.forename: D M
authors.initials: DM
authors.lastname: Denison
mesh_terms: D000293:Adolescent; D001827:Body Height; D001830:Body Surface Area; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D011652:Pulmonary Circulation; D012016:Reference Values; D012146:Rest