The continuum model and c-myc synthesis during the division cycle.
Discordant results on the synthesis of c-myc gene products during the division cycle are reanalyzed and shown to be understood in light of the continuum model. It is proposed that there is no G1-phase dependence of c-myc synthesis. The large amount of data supporting G1-specific syntheses and a G(0) state must be re-examined.
Cooper
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Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor 48109-0620.
D000818:Animals; D002453:Cell Cycle; D007399:Interphase; D008957:Models, Genetic; D009857:Oncogenes