title: [The significance of blood coagulation test in fulminant hepatic failure].
abstract: We treated 12 cases of fulminant hepatic failure with plasma exchange, cryofiltration and hemodialysis. Five cases were survived and 7 cases died. The liver volume measured by volus CT on admission was about 1106 ml in survived cases, and was about 457 ml in death cases. In cases which liver volume was under 600 ml, these prognoses were miserable. AT-III, PT and HPT activities were well correlated with liver volume (r = 0.85) and these activities were good indicator to treat the fulminant hepatic failure. The measurement of FBG and APTT were also useful for the estimation of the prognosis. But they were not becoming of indicator to treatment. We have no expectation to prognosis of the cases which PT, HPT and AT-III were under 15%, 10%, and 25%, respectively.
authors.affiliation: Sapporo Hokuyu Hospital, Artificial Organ & Transplantation Hospital.
authors.forename: A
authors.initials: A
authors.lastname: Kawamura
authors.forename: J
authors.initials: J
authors.lastname: Meguro
authors.forename: K
authors.initials: K
authors.lastname: Kukita
authors.forename: M
authors.initials: M
authors.lastname: Yonekawa
authors.forename: K
authors.initials: K
authors.lastname: Imai
authors.forename: N
authors.initials: N
authors.lastname: Kobayashi
authors.forename: K
authors.initials: K
authors.lastname: Kawamura
authors.forename: M
authors.initials: M
authors.lastname: Kasai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001780:Blood Coagulation Tests; D005260:Female; D006440:Hemofiltration; D006505:Hepatitis / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D011379:Prognosis; D006435:Renal Dialysis