title: Measurement of liver iron content in paraffin-embedded biopsies.
abstract: A reliable method for the determination of total liver iron in formalin-fixed, paraffin-embedded tissue is presented. The correlation with total liver iron in fresh tissue is good (r = 0.92). Material, which is processed routinely in the pathological anatomical department and stored in the archives, can be used for a quantitative iron determination for clinical or research purposes.
authors.affiliation: Department of Internal Medicine, De Wever-Hospital, Heerlen, The Netherlands.
authors.forename: C
authors.initials: C
authors.lastname: van Deursen
authors.forename: M
authors.initials: M
authors.lastname: de Metz
authors.forename: J
authors.initials: J
authors.lastname: Koudstaal
authors.forename: P
authors.initials: P
authors.lastname: Brombacher
mesh_terms: D001706:Biopsy; D006801:Humans; D007501:Iron / Q000032:analysis*; D008099:Liver / Q000032:analysis* / Q000473:pathology; D010232:Paraffin; D013054:Spectrophotometry, Atomic / Q000379:methods
chemical_list: D010232:Paraffin; D007501:Iron