Mechanism of antitumor activity of norspermidine, a structural homologue of spermidine.
Sunkara
P S
PS
Merrell Dow Research Institute, Cincinnati, Ohio 45215.
Zwolshen
J H
JH
Prakash
N J
NJ
Bowlin
T L
TL
D012437:Adenosylmethionine Decarboxylase / Q000378:metabolism; D000818:Animals; D000970:Antineoplastic Agents; D004273:DNA, Neoplasm / Q000096:biosynthesis; D006367:HeLa Cells; D007939:Leukemia L1210 / Q000188:drug therapy; D008223:Lymphoma / Q000188:drug therapy; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008938:Mitosis / Q000187:drug effects; D009363:Neoplasm Proteins / Q000096:biosynthesis; D009955:Ornithine Decarboxylase / Q000378:metabolism; D013095:Spermidine / Q000031:analogs & derivatives* / Q000494:pharmacology
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; C006760:norspermidine; D009955:Ornithine Decarboxylase; D012437:Adenosylmethionine Decarboxylase; D013095:Spermidine