title: Ocular side effects of isotretinoin therapy.
abstract: Isotretinoin (Accutane Capsules) is a synthetic vitamin A compound used for treatment of recalcitrant cystic acne. It has numerous ocular toxic side effects which include anterior segment inflammation, dry eye syndrome, contact lens intolerance, altered refraction, photosensitivity, and reduced night vision. Eye care practitioners should be aware of these potential side effects and be prepared to communicate with the prescribing physician if side effects present.
authors.forename: B E
authors.initials: BE
authors.lastname: Caffery
authors.forename: J E
authors.initials: JE
authors.lastname: Josephson
mesh_terms: D000869:Anterior Eye Segment / Q000187:drug effects; D004848:Epithelium / Q000187:drug effects; D005128:Eye Diseases / Q000139:chemically induced*; D006801:Humans; D015474:Isotretinoin; D009755:Night Blindness / Q000139:chemically induced; D010211:Papilledema / Q000139:chemically induced; D010787:Photosensitivity Disorders / Q000139:chemically induced; D012029:Refraction, Ocular; D012098:Reproduction / Q000187:drug effects; D012160:Retina / Q000187:drug effects; D014212:Tretinoin / Q000009:adverse effects*; D014801:Vitamin A / Q000009:adverse effects / Q000502:physiology
chemical_list: D014801:Vitamin A; D014212:Tretinoin; D015474:Isotretinoin