title: Definitive identification of human T cells in formalin fixed paraffin wax embedded tissue.
abstract: The use of a new monoclonal antibody, BF1, which reacts in routinely fixed tissues, directed against the beta chain of the T cell antigen receptor was assessed to determine its reactivity in a variety of normal tissues as well as in a number of B and T cell tumours and other lymphoid disorders. It reacted with all five of the unequivocal T cell tumours tested. BF1 will have widespread use in the assessment of lymphoid tissues in patients with the acquired immune deficiency syndrome (AIDS) and the differential diagnosis of tumours.
authors.affiliation: Pathology Department, St Mary's Hospital Medical School, London.
authors.forename: N D
authors.initials: ND
authors.lastname: Francis
authors.forename: D M
authors.initials: DM
authors.lastname: Clark
authors.forename: A W
authors.initials: AW
authors.lastname: Boylston
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D011948:Receptors, Antigen, T-Cell / Q000032:analysis; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D011948:Receptors, Antigen, T-Cell