title: N1-glucosides as urinary metabolites of sulphadimidine, sulphamerazine and sulphamethoxazole.
abstract: The synthesis and characterisation of the N1-beta-D-glucosides of the three title sulphonamides are described, and these conjugates are shown, by means of HPLC and MS, to be minor urinary metabolites of these drugs.
authors.affiliation: Department of Pharmaceutical Chemistry, School of Pharmacy, London, U.K.
authors.forename: B
authors.initials: B
authors.lastname: Ahmad
authors.forename: J W
authors.initials: JW
authors.lastname: Powell
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005960:Glucosides / Q000652:urine*; D006027:Glycosides / Q000652:urine*; D006801:Humans; D013058:Mass Spectrometry; D013416:Sulfamerazine / Q000652:urine*; D013418:Sulfamethazine / Q000652:urine*; D013420:Sulfamethoxazole / Q000652:urine*
chemical_list: D005960:Glucosides; D006027:Glycosides; D013418:Sulfamethazine; D013420:Sulfamethoxazole; D013416:Sulfamerazine