title: Manometric evaluation of esophageal motility in patients submitted to prophylactic variceal sclerosis.
abstract: Sclerotherapy of esophageal varices is an effective hemostatic treatment and may also prevent bleeding. In our study, we examined the effects of prophylactic sclerotherapy on esophageal motility in 15 patients with Child's A cirrhosis of the liver. All the patients underwent three manometric measurements, performed respectively before the sclerotherapy, 1 week after the eradication of varices, and 3 months later. The results of our study show that prophylactic sclerotherapy of esophageal varices does not significantly change the resting pressure and length of the lower esophageal sphincter. Neither the amplitude nor the duration of the postswallowing esophageal peristaltic waves is significantly influenced by sclerotherapy. However, sclerotherapy produces a significant increase in tertiary contractions in the distal esophagus, which could explain the onset of dysphagia among patients in whom postsclerotherapy stricture is not evident.
authors.affiliation: Department of Gastroenterology, Ospedale S. Martino, Genova, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Bovero
authors.forename: A
authors.initials: A
authors.lastname: Farese
mesh_terms: D004932:Esophageal and Gastric Varices / Q000517:prevention & control*; D004947:Esophagus / Q000187:drug effects / Q000503:physiopathology*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000627:therapeutic use*
chemical_list: D012597:Sclerosing Solutions