The characteristics and regional distribution of afferent fibres in the chorda tympani of the cat.
1. Experiments were carried out on the cat's tongue to investigate regional variations in sensitivity to gustatory and thermal stimuli and to determine whether taste buds responding to particular stimuli are unique to specific areas. 2. In ten cats, integrated whole-nerve activity was recorded from the left chorda tympani during stimulation of the anterior, middle or posterior segments of the tongue. The level of activity produced by gustatory or thermal stimuli increased towards the posterior segment of the tongue but the relative activity evoked by each stimulus was similar for each segment. 3. Recordings were made from 108 single units dissected from the chorda tympani; fifty-five responded principally to gustatory stimuli, twenty were principally thermosensitive and thirty-three were purely mechanosensitive. 4. The gustatory units could be subdivided according to the stimuli which evoked the most vigorous discharge; there were sixteen salt units, eighteen acid units, nineteen salt-acid units and two quinine units. The salt units had a higher level of spontaneous activity than the other groups and the acid units supplied more fungiform papillae with a greater separation between them. 5. The two quinine units were both located near to the mid-line posteriorly but all other groups of gustatory, thermosensitive and mechanosensitive units were distributed over all regions of the dorsal surface of the tongue and did not have higher discharge rates in specific areas. 6. Individual stimulation of the fungiform papillae supplied by a single unit revealed that similar responses were evoked from each papilla but stimulation of a single papilla supplied by two or more units could evoke a different response in each unit. 7. This study revealed that the relative sensitivity to gustatory and thermal stimuli was similar in each region of the tongue and that taste buds responding to particular stimuli are not confined to specific areas.
Robinson
P P
PP
Department of Physiology, Birmingham University Medical and Dental Schools.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D002415:Cats; D002814:Chorda Tympani Nerve / Q000166:cytology / Q000502:physiology*; D006358:Hot Temperature; D009412:Nerve Fibers / Q000502:physiology*; D009431:Neural Conduction; D009475:Neurons, Afferent / Q000502:physiology*; D013650:Taste Buds / Q000502:physiology; D014059:Tongue / Q000294:innervation*