Decrease in antimicrobial susceptibility of Bordetella bronchiseptica caused by antigenic modulation and phase variation.
The susceptibilities to 20 antimicrobial agents of Bordetella bronchiseptica variants in C mode and degraded phases were compared with those of their parents in X mode. Increases in MICs of 4- to 32-fold were observed for ampicillin, carbenicillin, erythromycin, novobiocin, rifampin, chloramphenicol, nalidixic acid, and oxolinic acid.
Ishikawa
H
H
Hokkaido Research Station, National Institute of Animal Health, Sapporo, Japan.
Isayama
Y
Y
Ohmae
K
K
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001884:Bordetella / Q000187:drug effects*; D004352:Drug Resistance, Microbial
D000900:Anti-Bacterial Agents