[Changes in the biosynthesis of nuclear proteins in the thymocytes of mice exposed to radiation and hydrocortisone].
Biosynthesis of nuclear proteins of mouse thymocytes affected by gamma-radiation and hydrocortisone was studied using two-dimensional electrophoresis. The two lympholytic agents were shown both to inhibit and to induce certain protein synthesis. The appearance of the same polypeptides after exposure to radiation and hydrocortisone indicated that these proteins possibly contribute to the implementation of the cell death programme.
Domashenko
A D
AD
Nazarova
L F
LF
Umanskiĭ
S R
SR
D000818:Animals; D006854:Hydrocortisone / Q000494:pharmacology*; D051379:Mice; D009687:Nuclear Proteins / Q000096:biosynthesis*; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects*
D009687:Nuclear Proteins; D006854:Hydrocortisone
Izmenenie biosinteza iadernykh belkov timotsitov mysheĭ pod deĭstviem oblucheniia i gidrokortizona.