title: [Determinations of blood theophylline level in a severe asthma attack in childhood treated with respirator therapy].
abstract: The authors describe the course of a severe asthma emergency in a boy aged 13 years. Respirator therapy and bronchial lavage were required. A therapeutically effective serum concentration was initially obtained by an aminophyllin infusion (dose 1.2 mg/kg b.w./h after bolus injection with 6 mg/kg b.w.). In the further course of treatment the theophyllin concentration in serum decreased considerably. The advantage of theophyllin determination for guaranteeing a safe therapy is explained on the base of this case report.
authors.affiliation: Kinderklinik, Bezirkskrankenhaus Neubrandenburg/DDR.
authors.forename: F
authors.initials: F
authors.lastname: Heydolph
authors.forename: M
authors.initials: M
authors.lastname: Schulz
authors.forename: R
authors.initials: R
authors.lastname: Budde
mesh_terms: D000293:Adolescent; D000628:Aminophylline / Q000008:administration & dosage; D001249:Asthma / Q000097:blood* / Q000188:drug therapy; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004630:Emergencies; D006801:Humans; D008297:Male; D012121:Respiration, Artificial; D013806:Theophylline / Q000493:pharmacokinetics*
chemical_list: D000628:Aminophylline; D013806:Theophylline
vernacular_title: Theophyllinblutspiegelbestimmungen bei einem schweren Asthmaanfall im Kindesalter unter Respiratortherapie.