title: [Preventive use of nitrofurantoin in recurrent urinary tract infections].
abstract: 51 patients suffering from chronic urinary tract infection were treated from 6 to 12 months with a single evening dose of 100 mg nitrofurantoin. The frequency of re-infection in the treatment period was compared with the same period before onset of therapy. The number of such re-infections was reduced significantly. Side effects of this therapy were substantial lower than after a three-times application per day. Gastrointestinal symptoms could be reduced in more than 50% of the cases by a combined therapy of 100 mg nitrofurantoin and 20 mg vitamin B6.
authors.affiliation: Klinik für Innere Medizin Bereiches Medizin, Ernst-Moritz-Arndt-Universität Greifswald.
authors.forename: G
authors.initials: G
authors.lastname: Kraatz
authors.forename: A
authors.initials: A
authors.lastname: Scherber
mesh_terms: D000293:Adolescent; D000328:Adult; D001437:Bacteriuria / Q000188:drug therapy; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009582:Nitrofurantoin / Q000627:therapeutic use*; D011704:Pyelonephritis / Q000188:drug therapy; D012008:Recurrence; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D009582:Nitrofurantoin
vernacular_title: Zur Nitrofurantoin-Prophylaxe rezidivierender Harnwegsinfektionen.