title: [Effect of sialadenectomy on hepatic carcinogenesis in rats induced by N-nitrosodiethylamine].
abstract: It is established that sialadenectomy leads to inhibition of hepatocarcinogenesis induced in adult rats by diethylnitrosamine, which is confirmed by a decrease in the incidence of tumours, their delayed growth and an increase of longevity. But sialadenectomy 2 weeks after the beginning of carcinogen treatment has no effect on the hepatocarcinogenesis. A significant molecular heterogeneity of the epidermal growth factor-competing activity is observed in acid-ethanol extracts of the liver tumour of the sialadenectomized rats.
authors.forename: L A
authors.initials: LA
authors.lastname: Osipova
authors.forename: N I
authors.initials: NI
authors.lastname: Nemliĭ
authors.forename: T A
authors.initials: TA
authors.lastname: Alekseeva
authors.forename: A I
authors.initials: AI
authors.lastname: Bykorez
mesh_terms: D000818:Animals; D004052:Diethylnitrosamine / Q000633:toxicity*; D004815:Epidermal Growth Factor / Q000032:analysis / Q000172:deficiency; D008099:Liver / Q000032:analysis; D008114:Liver Neoplasms, Experimental / Q000032:analysis / Q000139:chemically induced*; D008297:Male; D051381:Rats; D012469:Salivary Glands / Q000032:analysis / Q000502:physiology* / Q000601:surgery; D013997:Time Factors
chemical_list: D004052:Diethylnitrosamine; D004815:Epidermal Growth Factor
vernacular_title: Vliianie sialadenéktomii na gepatokantserogenez, indutsirovannyĭ u krys N-nitrozodiétilaminom.