title: The development of mast cells in facial skin, palate and tongue of the mouse.
abstract: This was examined in connective tissues of facial skin, palatal mucosa and tongue in fetal and adult mice. Mast cells were first observed in skin at 15 days of fetal age, but until 17 days in palate and tongue. With increasing age they increased in size and granularity. At birth they were 6-7 times more numerous per unit volume of tissue in skin compared with palate or tongue but, in the adult, numbers were similar in each region. Either mast cells enter developing tissues at different times or they differentiate and proliferate in some regions before they do so in others.
authors.affiliation: Unit of Anatomy in relation to Dentistry, United Medical School, Guy's Campus, London, England, U.K.
authors.forename: D A
authors.initials: DA
authors.lastname: Luke
mesh_terms: D000818:Animals; D002452:Cell Count; D005145:Face; D005333:Fetus / Q000166:cytology; D008407:Mast Cells / Q000166:cytology*; D051379:Mice; D009061:Mouth Mucosa / Q000166:cytology; D010159:Palate / Q000166:cytology*; D012867:Skin / Q000166:cytology*; D014059:Tongue / Q000166:cytology*