Growth hormone facilitates ovulation induction by gonadotrophins.
The addition of biosynthetic human growth hormone (GH) to treatment with human menopausal gonadotrophin (hMG) significantly augmented the ovarian response in four patients treated for in-vivo and three patients treated for in-vitro fertilization who had previously been resistant to hMG. The amount, duration of treatment and daily effective dose of hMG were all reduced by growth hormone. This action of growth hormone offers a new approach to ovulation induction.
Homburg
R
R
Cobbold Laboratories, Middlesex Hospital, London, UK.
Eshel
A
A
Abdalla
H I
HI
Jacobs
H S
HS
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006062:Gonadotropins / Q000008:administration & dosage / Q000627:therapeutic use*; D013006:Growth Hormone / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008597:Menstrual Cycle; D010062:Ovulation Induction / Q000379:methods*
D006062:Gonadotropins; D013006:Growth Hormone