[Determinations of blood theophylline level in a severe asthma attack in childhood treated with respirator therapy].
The authors describe the course of a severe asthma emergency in a boy aged 13 years. Respirator therapy and bronchial lavage were required. A therapeutically effective serum concentration was initially obtained by an aminophyllin infusion (dose 1.2 mg/kg b.w./h after bolus injection with 6 mg/kg b.w.). In the further course of treatment the theophyllin concentration in serum decreased considerably. The advantage of theophyllin determination for guaranteeing a safe therapy is explained on the base of this case report.
Heydolph
F
F
Kinderklinik, Bezirkskrankenhaus Neubrandenburg/DDR.
Schulz
M
M
Budde
R
R
D000293:Adolescent; D000628:Aminophylline / Q000008:administration & dosage; D001249:Asthma / Q000097:blood* / Q000188:drug therapy; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004630:Emergencies; D006801:Humans; D008297:Male; D012121:Respiration, Artificial; D013806:Theophylline / Q000493:pharmacokinetics*
D000628:Aminophylline; D013806:Theophylline
Theophyllinblutspiegelbestimmungen bei einem schweren Asthmaanfall im Kindesalter unter Respiratortherapie.