[An example of dominant heredity in the transmission of primary open-angle glaucoma in a northwestern region of Greece].
The authors have accomplished an epidemiological clinical and genetic study on primary open-angle glaucoma among 411 persons in the North Western district of Greece (Epirus), belonging to 4 genealogical trees. 112 of the 411 persons were offsprings aged 30 years or more, alive or dead, and they had direct blood-relation to the propositus. 35 of these offsprings were suffering from primary open-angle glaucoma. The classification and the number of the affected subjects suggested that one major gene, expressed by the autosomal dominant character, is the main factor for the heredity of primary open-angle glaucoma in Epirus-Greece.
Kitsos
G
G
Clinique Universitaire d'Ophtalmologie, Ionnina, Grèce.
Cote
G
G
Psilas
K
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005799:Genes, Dominant; D005902:Glaucoma, Open-Angle / Q000453:epidemiology / Q000235:genetics* / Q000635:transmission; D006115:Greece; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree
Un exemple d'hérédité dominante our la transmission du glaucome primitif à angle ouvert dans une région du nord-ouest de la Grèce.