Anthelmintic efficacies of fenbendazole, ivermectin, and levamisole against Nematodirus battus infections in lambs.
Anthelmintic efficacies of fenbendazole, ivermectin, and levamisole were evaluated against naturally acquired infections of Nematodirus battus in lambs. Four groups of 10 lambs each were used. Oral administration of 8 mg of levamisole/kg of body weight or 5 mg of fenbendazole/kg significantly (P less than 0.01) reduced the degree of infection by N battus (adults) by greater than 99%. An oral formulation of 200 micrograms of ivermectin/kg was 98% effective (P less than 0.01). Numbers of other Nematodirus spp (including N filicollis and N spathiger) were significantly reduced.
Zimmerman
G L
GL
College of Veterinary Medicine, Oregon State University, Corvallis 97331.
Hoberg
E P
EP
Rickard
L G
LG
Bishop
J K
JK
D000284:Administration, Oral; D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D004341:Drug Evaluation; D005273:Fenbendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D007559:Ivermectin / Q000008:administration & dosage / Q000627:therapeutic use*; D007978:Levamisole / Q000008:administration & dosage / Q000627:therapeutic use*; D009349:Nematode Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000517:prevention & control
D001562:Benzimidazoles; D007978:Levamisole; D005273:Fenbendazole; D007559:Ivermectin