title: Genetic polymorphisms of the Pmo1 and Pmo2 salivary proteins detected by the modified protein staining method.
abstract: Two polymorphic proteins, Pmo1 and Pmo2, were found in human parotid saliva by modifying the protein staining method of Sung & Smithies (1969). The inheritance of each polymorphism was controlled by a dominant allele at an autosomal locus. This hypothesis was supported by studies in 50 families including 103 children. The gene frequencies were Pmo1+ = 0.308, Pmo1- = 0.692, Pmo2+ = 0.026, Pmo2- = 0.974. The Pmo1 and Pmo2 proteins reacted immunologically with antisera prepared to salivary proline-rich proteins (Pr and Gl). The isoelectric point was in excess of 8.58. These results showed that the Pmo1 and Pmo2 proteins belong to the basic proline-rich proteins in human parotid saliva.
authors.affiliation: Department of Forensic Odontology, Tokyo Dental College, Chiba City, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Minaguchi
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
mesh_terms: D002648:Child; D004591:Electrophoresis, Polyacrylamide Gel; D005787:Gene Frequency; D005799:Genes, Dominant; D006801:Humans; D015151:Immunoblotting; D007525:Isoelectric Focusing; D008970:Molecular Weight; D011110:Polymorphism, Genetic; D012471:Salivary Proteins and Peptides / Q000235:genetics*
chemical_list: D012471:Salivary Proteins and Peptides