title: Plasma basal concentration of pancreatic polypeptide (PP) does not increase with ageing in the female Fischer (F-344) conscious rat.
abstract: Plasma concentrations of pancreatic polypeptide (PP) were compared for young (6 to 12 month-old) and old (24 to 25 month-old) conscious female Fischer rats by means of a radioimmunoassay. Basal plasma PP concentration was not different between young and old rats, nor was PP release stimulated by cerulein in either age group. The mechanism of PP release in rats is quite different from that in other species such as dogs and humans.
authors.affiliation: First Laboratory of Clinical Physiology, Tokyo Metropolitan Institute of Gerontology.
authors.forename: K
authors.initials: K
authors.lastname: Miyasaka
authors.forename: A
authors.initials: A
authors.lastname: Funakoshi
authors.forename: K
authors.initials: K
authors.lastname: Miyazaki
authors.forename: K
authors.initials: K
authors.lastname: Kitani
mesh_terms: D000375:Aging / Q000097:blood*; D000818:Animals; D005260:Female; D066298:In Vitro Techniques; D010191:Pancreatic Polypeptide / Q000097:blood*; D051381:Rats; D011916:Rats, Inbred F344
chemical_list: D010191:Pancreatic Polypeptide