[Clinical picture and course of children with CHARGE association].
Four children are described who presented malformations according to CHARGE-Association. The primary abnormalities were choanal atresia and/or Coloboma. All four cases exhibited esophageal malformations: atresia and/or fistulas. At autopsy, three children showed arhinencephaly which is rarely observed in patients with CHARGE-Association. Patients with the main features of CHARGE-Association have a very poor prognosis depending on the severity of the malformations.
Peters
H
H
Kinderneurologisches Zentrum des Landes Rheinland Pfalz, Institut für Soziale Pädiatrie, Mainz.
Pontz
B F
BF
D000015:Abnormalities, Multiple / Q000175:diagnosis; D002657:Child Development; D002754:Choanal Atresia / Q000175:diagnosis*; D003103:Coloboma / Q000175:diagnosis*; D004933:Esophageal Atresia / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013577:Syndrome
Klinisches Bild und Verlauf von Kindern mit CHARGE-Association.