title: A kinetic thermodynamic phenomenological approach to genetic expression of heat-shock proteins.
abstract: The approach of viewing complex biochemical phenomena as autocatalytic relaxation processes has been introduced previously (Liquori & Tripiciano, 1980; Liquori & Florio, 1985). In the present work this formalism is extended from its original framework regarding cell growth, to the problem of genetic expression. The case of the heat-shock response in organisms ranging from man to bacteria is discussed. Finally, we give some biochemical examples in which the new approach underlines evident temporal co-operativity.
authors.affiliation: International Centre of Theoretical Physics, Trieste, Italy.
authors.forename: J
authors.initials: J
authors.lastname: Chela-Flores
authors.forename: A M
authors.initials: AM
authors.lastname: Liquori
authors.forename: A
authors.initials: A
authors.lastname: Florio
mesh_terms: D005786:Gene Expression Regulation; D006360:Heat-Shock Proteins / Q000096:biosynthesis / Q000235:genetics*; D006801:Humans; D007700:Kinetics; D008957:Models, Genetic; D013696:Temperature; D013816:Thermodynamics
chemical_list: D006360:Heat-Shock Proteins