title: [Monoclonal antibody assessment of lymphocyte subpopulations in rheumatoid arthritis in adult patients in relation to stage and treatment].
abstract: Twenty patients with various stages of RA were examined. They included: 1) 7 cases in Steinbroker stage 1 (onset); 2) 13 cases in Steinbroker stage 2-3 (chronic). The group was divided into 16 treated and 4 untreated cases. Monoclonal antibodies were used to assay T3, T4, T8 and T4/T8 ratio and the results were compared with those in a control group. The results showed a T8 deficit and a consequent change in the T4/T8 ratio in untreated subjects with "onset" RA. The immune situation of the chronic and treated cases was very similar to that in the control group probably as a result of treatment.
authors.affiliation: Cattedra di Reumatologia, Università degli Studi di Palermo.
authors.forename: A
authors.initials: A
authors.lastname: Pappalardo
authors.forename: M
authors.initials: M
authors.lastname: Musso
authors.forename: L
authors.initials: L
authors.lastname: Sallì
authors.forename: P
authors.initials: P
authors.lastname: Di Prima
authors.forename: V
authors.initials: V
authors.lastname: Accurso
authors.forename: E
authors.initials: E
authors.lastname: Caradonna
mesh_terms: D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal; D001172:Arthritis, Rheumatoid / Q000145:classification / Q000276:immunology* / Q000628:therapy; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000145:classification* / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal
vernacular_title: Valutazione con anticorpi monoclonali delle sub-popolazioni linfocitarie nell'artrite reumatoide dell'adulto, in rapporto allo stadio ed al trattamento.