[New heterocyclic derivatives of benzimidazole with germicidal activity. V. Synthesis and activity of new derivatives of di-2-benzimidazolyl-2,5-furan].
In continuation of the research in the field of germicidal and antimycotic agents, the synthesis of 14 new derivatives of di-2-benzimidazolyl-2,5-furan is described. These derivatives are differently substituted (R not equal to R') in the position 5 of the two benzene rings. These new compounds showed no germicidal or fungicidal activity, when tested on different cultures. New compounds are under investigation.
Pedini
M
M
Departement de Medecine, Experimentale et de Sciences Biochimiques, Università degli Studi di Perugia, Italie.
Alunni Bistocchi
G
G
De Meo
G
G
Ricci
A
A
Bastianini
L
L
Sposini
T
T
Jacquignon
P
P
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship
D000890:Anti-Infective Agents; D001562:Benzimidazoles; C031000:benzimidazole
Nouveaux derives heterocycliques du benzimidazole a activite germicide. V. Synthese et activité de nouveaux di-2-benzimidazolyl-2,5-furranes asymétriques.