title: Craniofacial resection for anterior skull base tumors.
abstract: We present the results of treatment of 30 patients with anterior skull base tumors operated on over an 11-year period. At the time of surgery, intracranial invasion was present in 10 patients. Histology revealed epithelial tumors in 18 patients, sarcoma in 6, esthesioneuroblastoma in 4, and 2 miscellaneous histologies. The overall median survival was 5 years and varied according to histology and grade of tumor. Currently malignancies involving the skull base can be successfully resected using a craniofacial approach, with minimum operative mortality. Limited intracranial invasion need not necessarily represent a major contraindication of this procedure if morbidity can be kept to a minimum.
authors.affiliation: St. Lukes/Roosevelt Hospital Center, New York, New York.
authors.forename: N
authors.initials: N
authors.lastname: Sundaresan
authors.forename: J P
authors.initials: JP
authors.lastname: Shah
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000601:surgery; D011183:Postoperative Complications; D011379:Prognosis; D012888:Skull Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*