Cutaneous presentation of prolymphocytic leukaemia.
We report a case of prolymphocytic leukaemia which presented with annular, purpuric, erythematous plaques in the skin. Histology of the lesions showed cutaneous invasion with leukaemic cells. The lesions cleared with chlorambucil and prednisolone, and the leukaemic state responded to deoxycoformycin, an experimental anti T cell agent.
Logan
R A
RA
St. John's Hospital for Diseases of the Skin, London, U.K.
Smith
N P
NP
D002699:Chlorambucil / Q000627:therapeutic use; D003070:Coformycin / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D015649:Pentostatin; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000097:blood / Q000188:drug therapy / Q000473:pathology*
D003070:Coformycin; D002699:Chlorambucil; D015649:Pentostatin; D011239:Prednisolone