title: The use of alpha 2HS-glycoprotein and group specific component in typing forensic blood samples for discriminative and investigative purposes.
abstract: Methods are described for phenotyping alpha 2HS-glycoprotein (A2HS) and group specific component (GC) in plasma and blood-stains. The methods have been developed to be sensitive, to provide unequivocal results and to give maximal information from minimal amounts of sample. In attempting to fulfill the last criterion, a new method is described for the simultaneous typing of alpha 2 HS-glycoprotein and group-specific component from serum or plasma samples. The use of these proteins in determining the racial origin of a blood sample is also discussed.
authors.affiliation: Central Research Establishment, Home Office Forensic Science Service, Aldermaston, Reading, Berkshire, England.
authors.forename: S A
authors.initials: SA
authors.lastname: Westwood
mesh_terms: D001788:Blood Grouping and Crossmatching / Q000379:methods*; D001798:Blood Proteins / Q000032:analysis / Q000235:genetics*; D001801:Blood Stains; D005554:Forensic Medicine; D006801:Humans; D007525:Isoelectric Focusing; D009439:Neuraminidase; D010641:Phenotype; D044469:Racial Groups / Q000235:genetics; D014809:Vitamin D-Binding Protein / Q000032:analysis / Q000235:genetics*; D060749:alpha-2-HS-Glycoprotein
chemical_list: C556354:AHSG protein, human; D001798:Blood Proteins; D014809:Vitamin D-Binding Protein; D060749:alpha-2-HS-Glycoprotein; D009439:Neuraminidase