Prevalence of HIV-antibodies in patients with haemophilia in Hungary.
Incidence of HIV antibodies have been studied in 617 patients with congenital bleeding disorders. Screening was performed with the Organon ELISA test, repeatedly positive samples were tested with four different confirmatory assays. HIV antibodies were found in 3/356 patients with haemophilia A, 21/114 patients with haemophilia B, 3/123 patients with von Willebrand disease and in 1/24 patients with other types of congenital coagulation disorders. All the 28 seropositive patients were treated with imported coagulation factor, mostly with factor IX concentrates. No patient treated exclusively with nationally produced factor preparations between 1981 and 1985 was found to be anti-HIV positive.
Ujhelyi
E
E
National Institute of Haematology and Blood Transfusion, Budapest, Hungary.
Králl
G
G
Füst
G
G
Medgyesi
G A
GA
Hollán
S R
SR
Zimonyi
I
I
Berkessy
S
S
Nagy
K
K
Földes
I
I
Mayer
V
V
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000635:transmission*; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005164:Factor IX / Q000627:therapeutic use; D015483:HIV Antibodies; D006679:HIV Seropositivity / Q000453:epidemiology*; D006467:Hemophilia A / Q000628:therapy*; D006801:Humans; D006814:Hungary; D008403:Mass Screening; D012747:Sexual Partners; D065227:Transfusion Reaction; D014842:von Willebrand Diseases / Q000628:therapy
D000914:Antibodies, Viral; D015483:HIV Antibodies; D005164:Factor IX