Preparation of microencapsulated liposomes.
Liposomal microcapsules were prepared by encapsulating a liposome suspension in a nylon wall formed by the interfacial polymerization technique. The resulting microcapsules were washed in ether to remove the chloroform and cyclohexane. Residual ether was removed by rinsing with distilled water prior to resuspending the microcapsules in aqueous medium. The encapsulation efficiency of the microcapsules toward liposomes was dependent on the lipid composition of the liposomes. The liposomal nylon microcapsules possess sustained release properties when compared with the simple nylon microcapsules.
Yeung
V W
VW
Chelsea Department of Pharmacy, King's College (KQC), University of London.
Nixon
J R
JR
D002784:Cholesterol; D004339:Drug Compounding; D008081:Liposomes; D009757:Nylons; D010713:Phosphatidylcholines
D008081:Liposomes; D009757:Nylons; D010713:Phosphatidylcholines; D002784:Cholesterol