title: [Experimental analysis of the development of arterial hypertension in aging].
abstract: The specifics of changes occurring in arterial BP and hemodynamics during a reproduction of various arterial hypertension models were studied in adult and old rabbits. In reproduction of reflexogenic and vasopressor hypertension, the animals revealed irregular changes in electrical activity of hypothalamic nuclei. Age-related differences of changes in the renin-aldosterone system were found. The data obtained suggest that changes of neural and hormonal control associated with ageing promote the development of arterial hypertension in old age.
authors.forename: V V
authors.initials: VV
authors.lastname: Frol'kis
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D001794:Blood Pressure; D004594:Electrophysiology; D005260:Female; D006439:Hemodynamics; D006973:Hypertension / Q000503:physiopathology*; D007031:Hypothalamus / Q000503:physiopathology; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012084:Renin-Angiotensin System; D014667:Vasopressins / Q000502:physiology
chemical_list: D014667:Vasopressins
vernacular_title: Eksperimental'nyĭ analiz razvitiia arterial'noĭ gipertenzii v starosti.