title: Applications of plasma desorption mass spectrometry in peptide and protein chemistry.
abstract: Molecular weight determination by plasma desorption (PD) mass spectrometry has been used in the different stages of protein sequence determination. It has been found to be a very valuable addition to the traditional techniques. For analysis in biotechnological development and production PD mass spectrometry meets the requirements for speed, precision and mass range. The amount of information can be increased by combining 'wet' biochemical procedures with analysis by PD mass spectrometry.
authors.affiliation: Department of Molecular Biology, Odense University, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Roepstorff
authors.forename: P F
authors.initials: PF
authors.lastname: Nielsen
authors.forename: K
authors.initials: K
authors.lastname: Klarskov
authors.forename: P
authors.initials: P
authors.lastname: Højrup
mesh_terms: D000595:Amino Acid Sequence; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D006868:Hydrolysis; D013058:Mass Spectrometry; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis*; D011506:Proteins / Q000032:analysis*; D014357:Trypsin
chemical_list: D010455:Peptides; D011506:Proteins; D014357:Trypsin