title: Biological vulnerability to depression: replication of MAO and evoked potentials as risk factors.
abstract: In previous work, we have reported that specific combinations of platelet (MAO) activity and evoked potential augmenting/reducing (AR) are associated with risk for affective disorders. This new study screened 271 college freshmen solely on MAO and AR and selected a sample with extreme values on both measures. These students were interviewed with the Diagnostic Interview Schedule and they completed a family history questionnaire and psychosocial scales. Following the previous work, the same MAO and AR combinations were related to the frequency of major depression and a family history of psychiatric disorder.
authors.affiliation: Department of Psychiatry, University of California, Irvine.
authors.forename: R J
authors.initials: RJ
authors.lastname: Haier
authors.forename: M S
authors.initials: MS
authors.lastname: Buchsbaum
authors.forename: E
authors.initials: E
authors.lastname: DeMet
authors.forename: J
authors.initials: J
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D001143:Arousal / Q000502:physiology*; D001792:Blood Platelets / Q000201:enzymology*; D003866:Depressive Disorder / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D004569:Electroencephalography; D005074:Evoked Potentials, Visual; D006801:Humans; D008995:Monoamine Oxidase / Q000097:blood*; D011581:Psychological Tests; D012307:Risk Factors
chemical_list: D008995:Monoamine Oxidase