[The in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections].
In this study the in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections was examined. Of 80 isolates (24 E. coli, 10 Enterobacter, 10 Klebsiella, 23 Proteus, 10 Pseudomonas, 2 Morganella and 1 Serratia) 49 were from inpatients, and 31 were from outpatients. Ciprofloxacin was the most potent compound and no resistant strain was found against ciprofloxacin, while 1 Enterobacter strain and 1 Pseudomonas strain were found to be resistant to both ofloxacin and pefloxacin. Another Pseudomonas strain was resistant to pefloxacin only. All of the resistant bacteria were from nosocomial infections.
Tunçkanat
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F
Hacettepe Universitesi, Tip Fakültesi, Mikrobiyoloji Anabilim Dali Araştirma Görevlisi.
Yuluğ
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N
D000890:Anti-Infective Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects*; D006801:Humans; D015242:Ofloxacin / Q000494:pharmacology; D015366:Pefloxacin / Q000494:pharmacology; D011549:Pseudomonas / Q000187:drug effects*; D014552:Urinary Tract Infections / Q000382:microbiology*
D000890:Anti-Infective Agents; D015366:Pefloxacin; D002939:Ciprofloxacin; D015242:Ofloxacin
Idrar yolu infeksiyonlarindan izole edilen çeşitli gram negatif bakteri türlerine karşi ofloxacin, pefloxacin ve ciprofloxacin'in in vitro aktiviteleri.