title: The characterization of structural variations within a crystal field.
abstract: The technique of correlation averaging is refined by the use of multivariate statistical analysis and classification. The refined method can deal with the presence of structural variations within a crystal field. A low-dose image of a crotoxin crystal embedded in ice is used to demonstrate that crystallographic structural parameters characterizing the different areas of such a crystal with varying structure can be extracted rigorously and reproducibly.
authors.affiliation: Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201-0509.
authors.forename: J
authors.initials: J
authors.lastname: Frank
authors.forename: W
authors.initials: W
authors.lastname: Chiu
authors.forename: L
authors.initials: L
authors.lastname: Degn
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D003435:Crotalid Venoms / Q000032:analysis*; D003439:Crotoxin / Q000032:analysis*; D003460:Crystallization; D005583:Fourier Analysis; D007053:Ice; D008854:Microscopy, Electron / Q000379:methods*; D012911:Snakes; D012984:Software; D014961:X-Ray Diffraction
chemical_list: D003435:Crotalid Venoms; D007053:Ice; D003439:Crotoxin