title: Ocular fluorescein clearance in patients with hypotony secondary to chronic uveitis.
abstract: The development of hypotony is not uncommon in patients with uveitis. Recent evidence suggests that prostaglandins may cause reduction in intraocular pressure by increasing uveoscleral outflow. Ocular fluorescein clearance was measured in patients with hypotony due to chronic uveitis. The mean fluorescein clearance was found to be 0.44/hr., which is consistent with the results found by other investigators in normal subjects.
authors.affiliation: Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
authors.forename: D C
authors.initials: DC
authors.lastname: Herman
authors.forename: A G
authors.initials: AG
authors.lastname: Palestine
authors.forename: R B
authors.initials: RB
authors.lastname: Nussenblatt
mesh_terms: D000287:Administration, Topical; D000867:Anterior Chamber / Q000378:metabolism; D003315:Cornea / Q000378:metabolism; D005123:Eye / Q000378:metabolism*; D005452:Fluoresceins / Q000493:pharmacokinetics*; D006801:Humans; D007429:Intraocular Pressure; D013997:Time Factors; D014605:Uveitis / Q000150:complications*; D014822:Vitreous Body / Q000378:metabolism
chemical_list: D005452:Fluoresceins