The combined effects of mixtures of ionizing radiations.
Ionizing radiation is a special group of toxic agents whose general interaction can be calculated. This was demonstrated using a radiation interaction model previously published. In this paper, this model is refined and mathematically reformulated using a unified set of assumptions. It postulates the existence of a common intermediate lesion and the relative action of lesions before, at and after this common stage. General quantitative dose-effect relationships of mixed radiations can be derived from the dose-effect relationships of the components in the mixture.
Lam
G K
GK
TRIUMF, University of British Columbia, Vancouver, Canada.
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D008433:Mathematics; D008954:Models, Biological; D011839:Radiation, Ionizing / Q000009:adverse effects*