title: [Synthesis and biological activity of 5-phenyl-1,3,4-benzotriazepines. 14. The reactions of 2-thioxo-5-phenyl-1,3,4-benzotriazepines].
abstract: The interaction of 2-aminoethanol and 2-thioxo-5-phenyl-1,3,4-benzotriazepines in abs. dioxane under refluxing conditions was investigated. Depending on the substitution of the triazepine ring several products are formed. The S-N-exchange to form the corresponding 2-(2-hydroxyethyl)-amino derivatives only takes place if the nitrogen atoms of the heterocycle are unsubstituted.
authors.affiliation: Sektion Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.
authors.forename: O
authors.initials: O
authors.lastname: Morgenstern
authors.forename: A
authors.initials: A
authors.lastname: Besch
authors.forename: P
authors.initials: P
authors.lastname: Richter
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D013871:Thiones / Q000138:chemical synthesis
chemical_list: D006571:Heterocyclic Compounds; D013871:Thiones
vernacular_title: Synthese und biologische Aktivität von 5-phenyl-1,3,4-benzotriazepinen. 14 Mitteilung: Untersuchungen zur Reaktion von 2-Thioxo-5-phenyl-1,3,4-benzotriazepinen mit 2-Aminoethanol.