Advanced atrioventricular block in a neonate with lupus erythematosus and anti-SS-A antibodies.
Recent studies suggested that the involvement of anti-SS-A and anti-SS-B antibodies in the pathogenesis of neonatal lupus erythematosus and congenital heart block. We here describe a female neonate with lupus erythematosus, advanced atrioventricular block, and a positive test for anti-SS-A antibodies. The findings of His-bundle recordings are presented.
Shimizu
T
T
Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan.
Ino
T
T
Nishimoto
K
K
Iwahara
M
M
Yamashiro
Y
Y
Yabuta
K
K
D000974:Antibodies, Antinuclear / Q000032:analysis*; D002036:Bundle of His / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000151:congenital* / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D008180:Lupus Erythematosus, Systemic / Q000151:congenital* / Q000276:immunology
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies