title: Hemoglobin D-beta (0) thalassemia. A case report and family study.
abstract: Findings are presented on a Pakistani family in Doha, Qatar with hemoglobin D-Los Angeles (alpha 2 beta 3 121 (glutamine----glycine) and thalassemia trait. The propositus, a child, has hemoglobin D-beta(0) thalassemia, and suffers from moderately severe hemolytic anemia. The father has beta-thalassemia trait, and the mother is heterozygous for hemoglobin D-Los Angeles. This, the eighth confirmed case in the medical literature, is reported to emphasize its clinical manifestations and genetic basis.
authors.affiliation: Department of Pediatrics, Hamad General Hospital, Qatar, Arabian Gulf.
authors.forename: S T
authors.initials: ST
authors.lastname: Dawod
authors.forename: M
authors.initials: M
authors.lastname: Abulaban
authors.forename: K
authors.initials: K
authors.lastname: Kamel
authors.forename: T H
authors.initials: TH
authors.lastname: Huisman
mesh_terms: D006455:Hemoglobins, Abnormal / Q000032:analysis / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male; D010154:Pakistan; D013789:Thalassemia / Q000235:genetics* / Q000473:pathology
chemical_list: D006455:Hemoglobins, Abnormal; C026237:hemoglobin D Punjab