Formation of N-acetyl-p-benzoquinone imine, the well-known toxic metabolite of acetaminophen, by the reaction of acetaminophen with nitrite under model stomach conditions.
Ohta
T
T
Oribe
H
H
Ide
M
M
Takitani
S
S
D000082:Acetaminophen / Q000032:analysis* / Q000378:metabolism; D016227:Benzoquinones; D005753:Gastric Mucosa / Q000378:metabolism; D007097:Imines / Q000138:chemical synthesis*; D008954:Models, Biological; D009573:Nitrites
D016227:Benzoquinones; D007097:Imines; D009573:Nitrites; D000082:Acetaminophen; C028473:N-acetyl-4-benzoquinoneimine