Risk factors for Paget's disease: a new hypothesis.
A cross-sectional study was carried out in order to investigate likely risk factors in Paget's disease of bone. Associations were analysed by multivariate logistic regression. The odds ratio calculated for the consumption of bovid meat without sanitary control is high (odds ratio 2.18 95% Cl 1.05-4.49) and was not affected by other variables in our study. This finding supports the hypothesis of an infective slow agent in the genesis of Paget's disease of bone.
Piga
A M
AM
Department of Rheumatology, Ramón y Cajal Hospital, Madrid, Spain.
López-Abente
G
G
Ibáñez
A E
AE
Vadillo
A G
AG
Lanza
M G
MG
Jodra
V M
VM
D000368:Aged; D000818:Animals; D003430:Cross-Sectional Studies; D005513:Food Inspection; D006041:Goats; D006801:Humans; D008460:Meat / Q000009:adverse effects; D008875:Middle Aged; D010001:Osteitis Deformans / Q000453:epidemiology* / Q000209:etiology; D012307:Risk Factors; D012756:Sheep; D013030:Spain