Vasoocclusion with homozygous hemoglobin-C disease.
Hemoglobin-CC is a relatively uncommon hemoglobinopathy, seen primarily in the black population. These patients usually have a mild clinical course, without significant risk of vasoocclusive crises. There are no routine recommendations for preparation prior to surgery. We present a patient who developed a clinical picture suggestive of major vasoocclusion after cardiac by-pass surgery. In retrospect, these signs appear to be the result of hemodynamic instability and cardiogenic shock instead of vasoocclusion.
Fort
J A
JA
Division of Pediatric Hematology-Oncology, University of Florida, Gainesville 32611.
Graham-Pole
J R
JR
Chopik
J
J
D001024:Aortic Valve Stenosis / Q000601:surgery; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D002648:Child; D005078:Exchange Transfusion, Whole Blood; D006445:Hemoglobin C Disease / Q000150:complications*; D006801:Humans; D008297:Male; D013927:Thrombosis / Q000209:etiology*