title: Systemic sclerosis in association with multiple primary pulmonary malignancy--a marker of internal malignancy?
abstract: Multiple pulmonary malignancy is uncommon and has not been reported in association with systemic sclerosis. We now report such a case in which it is likely that the connective tissue disease occurred as a marker of the internal malignancy. Systemic sclerosis is not generally a reliable indicator of malignant change, but it is possible that in patients who are immunosuppressed, either therapeutically or inherently, the onset of systemic sclerosis should prompt investigation for an underlying cause.
authors.affiliation: Department of Dermatology, University Hospital, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Goodfield
authors.forename: L G
authors.initials: LG
authors.lastname: Millard
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging; D011859:Radiography; D012595:Scleroderma, Systemic / Q000150:complications*