title: Effects of spinal cord stimulation on spasticity and spasms secondary to myelopathy.
abstract: 16 subjects with severe spasms secondary to traumatic and nontraumatic myelopathy underwent epidural spinal cord stimulation. 4 patients had a complete motor and sensory spinal cord lesion. 6 of the subjects with an incomplete spinal cord lesion were ambulatory. All patients had previously undergone extensive trials with medications and physical therapy. All 14 subjects in whom a satisfactory placement of the electrode could be obtained had a reduction in the severity of the spasms. In 6 patients, the spasms were almost abolished. Extremity, trunkal and abdominal spasms were affected. Clonus in the upper extremities was consistently reduced. Marked improvement in bladder and bowel function was observed in each of 2 subjects. In over 1-year follow-up, 5 subjects show persistence of the results, with less stimulation required to maintain the therapeutic effects. No neurological deterioration occurred following the procedure or after long-term spinal stimulation. 1 patient showed after several months of continuous stimulation increased voluntary motor control present only when spinal cord stimulation was activated. Complications included 1 system infection, 1 electrode migration, 1 wire breakage and skin breakdown at a connector site, development of high impedance in 1 electrode and 1 skin breakdown over the lead.
authors.affiliation: Department of Neurosurgery, Jefferson Medical College, Philadelphia, Pa.
authors.forename: G
authors.initials: G
authors.lastname: Barolat
authors.forename: J B
authors.initials: JB
authors.lastname: Myklebust
authors.forename: W
authors.initials: W
authors.lastname: Wenninger
mesh_terms: D000328:Adult; D004599:Electric Stimulation Therapy / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D012007:Rectum / Q000503:physiopathology; D013035:Spasm / Q000209:etiology / Q000628:therapy*; D013119:Spinal Cord Injuries / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D013128:Spinal Osteophytosis / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D001743:Urinary Bladder / Q000503:physiopathology