A new duplication at the C4B locus associated with the HLA-Aw68, Cw8, Bw65 haplotype.
A family with a cross-over between HLA-B and HLA-DR was analysed for its complement alleles. This allowed location of the cross-over between HLA-B and C4. Furthermore, the same family showed a previously undescribed duplication at the C4B locus (C4B* 2,2) that was associated with the HLA-Aw68, Cw8, Bw65, C2*1, Bf*S, C4A*2, DR7, DQw2 haplotype.
Borelli
I
I
Dipartimento di Genetica, Università degli Studi di Torino, Italy.
Crepaldi
T
T
Frattasio
C
C
Curtoni
E S
ES
D000328:Adult; D000483:Alleles; D002648:Child; D003434:Crossing Over, Genetic; D004586:Electrophoresis; D005260:Female; D015234:HLA-A Antigens / Q000032:analysis / Q000235:genetics*; D015235:HLA-B Antigens / Q000032:analysis / Q000235:genetics*; D015236:HLA-C Antigens / Q000032:analysis / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D008297:Male
D015234:HLA-A Antigens; C053029:HLA-A*68 antigen; D015235:HLA-B Antigens; D015236:HLA-C Antigens; C524551:HLA-C*08 antigen