title: [Combination therapy of transcutaneous electric nerve stimulation and iontophoresis with benzydamine and diclofenac].
abstract: Combined Therapy of Transcutaneous Electrical Nerve Stimulation and Iontophoresis with Benzydamine and Diclofenac. The combination of transcutaneous electrical nerve stimulation (TENS) and the iontophoresis of benzydamine and diclofenac in a counter-current field is a new method in the treatment of chronical pain of the head and neck region. Prior to a clinical study this method was tested in a preliminary examination in 15 healthy volunteers. Clinical and physical data were investigated from which a theoretical maximum value of the quantity of iontophorised non-steroidal antiphlogistics (NSAI) could be calculated. The actual achievable absorption is discussed. Based on these data it is concluded that a good effective tissue concentration of benzydamine and diclofenac can be achieved with iontophoresis by means of TENS.
authors.affiliation: Abteilung für Mund-, Kiefer- und Gesichtschirurgie im Bundeswehrkrankenhaus, Universität Ulm, Donau.
authors.forename: A
authors.initials: A
authors.lastname: Bremerich
authors.forename: W
authors.initials: W
authors.lastname: Wiegel
mesh_terms: D001591:Benzydamine / Q000009:adverse effects / Q000627:therapeutic use*; D001831:Body Temperature / Q000187:drug effects; D003131:Combined Modality Therapy; D004008:Diclofenac / Q000009:adverse effects / Q000627:therapeutic use*; D004599:Electric Stimulation Therapy / Q000009:adverse effects; D006257:Head; D006801:Humans; D007478:Iontophoresis; D009333:Neck; D010146:Pain / Q000188:drug therapy; D059408:Pain Management; D011720:Pyrazoles / Q000627:therapeutic use*; D004561:Transcutaneous Electric Nerve Stimulation / Q000009:adverse effects
chemical_list: D011720:Pyrazoles; D004008:Diclofenac; D001591:Benzydamine
vernacular_title: Kombinationstherapie von Transkutaner Elektrischer Nerven-Stimulation und Iontophorese mit Benzydamin und Diclofenac.