title: Pituitary pathology in Cushing's disease. Histology and morphometry of pituitary tissues removed through microsurgery.
abstract: 58 cases of Cushing's disease were studied after selective transsphenoidal surgery, by means of histology, immunocytochemistry and morphometry. The qualitative and quantitative results, related to the clinical follow-up of the patients indicated that: 1) when a well-defined tumor was found (62% of the patients), successful outcomes occurred in 88% of the cases, 2) when a tumor could not be found, successful outcomes amounted to only 33% of the cases, a rate that might be related to a surgical exploration of the basophil cell zone "invading" the neural lobe, thus questioning a role of this zone, at least in some Cushing's diseases.
authors.affiliation: Laboratoire d'Histologie, Faculté de Médecine Pitié-Salpêtrière, Paris.
authors.forename: L
authors.initials: L
authors.lastname: Olivier
authors.forename: E
authors.initials: E
authors.lastname: Vila-Porcile
mesh_terms: D000236:Adenoma / Q000473:pathology* / Q000601:surgery; D003480:Cushing Syndrome / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008866:Microsurgery; D010902:Pituitary Gland / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000473:pathology* / Q000601:surgery