The assignment of the human gene coding for complement C5 to chromosome 9q22-9q33.
The presence or absence of the human gene for the fifth component of complement (C5) was analysed in 19 human-rodent hybrid cell lines by hybridization to a radiolabelled probe derived from a human C5 cDNA clone. The segregation of C5 in these hybrids suggested that the gene is localized on chromosome 9, in the region 9q21-9qter. In situ hybridization refined the assignment of C5 to chromosome 9q22-33.
Jeremiah
S J
SJ
Galton Laboratory, University College London.
West
L F
LF
Davis
M
M
Povey
S
S
Carritt
B
B
Fey
G H
GH
D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D002899:Chromosomes, Human, Pair 9; D003182:Complement C5 / Q000235:genetics*; D006224:Cricetinae; D015342:DNA Probes; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D009693:Nucleic Acid Hybridization; D051381:Rats
D003182:Complement C5; D015342:DNA Probes