title: [Acute recurrent pancreatitis as the main symptom of lupus erythematosus disseminatus in childhood].
abstract: A 17 year old girl with chronic relapsing pancreatitis since the age of 11 developed focal seizures, leukopenia, anemia and thrombozytopenia, signs suggesting lupus erythematodes. All immunologic investigations, including tests for Anti-DNS-Antibodies were negative, however. Therapy with prednisone and azathioprine resulted in clinical remission. Reduction of the immunosuppression lead to a severe crisis, which was controlled by plasmaseparation and cyclophosphamide. Subsequent analysis of circulating immune complexes revealed bound anti-DNS-antibodies.
authors.affiliation: Kinderklinik mit Poliklinik, Universität Erlangen-Nünberg.
authors.forename: T
authors.initials: T
authors.lastname: Rupprecht
authors.forename: D
authors.initials: D
authors.lastname: Wenzel
authors.forename: D
authors.initials: D
authors.lastname: Michalk
mesh_terms: D000208:Acute Disease; D000974:Antibodies, Antinuclear / Q000032:analysis; D002648:Child; D004247:DNA / Q000276:immunology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D010186:Pancreatic Function Tests; D010195:Pancreatitis / Q000209:etiology*; D012008:Recurrence
chemical_list: D000974:Antibodies, Antinuclear; D004247:DNA
vernacular_title: Akut rezidivierende Pankreatitis als Leitsymptom eines Lupus erythematodes disseminatus im Kindesalter.