Gluten-sensitive enteropathy and systemic lupus erythematosus.
A patient with systemic lupus erythematosus developed gluten-sensitive enteropathy, or celiac sprue. The patient's histocompatibility antigens included HLA-B8 and HLA-DR3, previously found to have a high frequency in gluten-sensitive enteropathy and possibility increased as well in systemic lupus erythematosus. Such histocompatibility antigens are common to a variety of autoimmune disorders. An immune basis for the association is discussed herein.
Rustgi
A K
AK
Department of Medicine, Beth Israel Hospital, Boston, MA.
Peppercorn
M A
MA
D002446:Celiac Disease / Q000150:complications* / Q000235:genetics / Q000276:immunology; D005260:Female; D006680:HLA Antigens / Q000235:genetics; D015795:HLA-B8 Antigen; D006684:HLA-DR Antigens / Q000235:genetics; D015803:HLA-DR3 Antigen; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D008875:Middle Aged
D006680:HLA Antigens; D015795:HLA-B8 Antigen; D006684:HLA-DR Antigens; D015803:HLA-DR3 Antigen