Mycoses in immunocompromised patients. An histopathologic study of 61 cases.
The histopathologic pattern of secondary mycoses in 61 immunocompromised patients is presented. The underlying diseases were: neoplasms, organ transplants, AIDS and a variety of other debilitating diseases. Three patients with AIDS had a double fungal infection. Candida spp. accounted for the majority of deep-seated mycoses, with 27 cases (44.2%); disseminated candidiasis was responsible of 18.5% of these patients death. Aspergillosis was seen in 23 subjects (37.7%), 18 of them (78.2%) died for systemic infection. These patients were severely debilitated by disease and/or iatrogenic procedures. The other fungal infections were: actinomycosis (10 cases), gerotrichosis (2 cases), histoplasmosis (1 case) and cerebral phaeohyphomycosis (1 case).
Masini
T
T
Institute of Pathological Anatomy, University of Milan, Italy.
Ghidoni
P
P
Riviera
L
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001228:Aspergillosis / Q000209:etiology / Q000473:pathology; D002177:Candidiasis / Q000209:etiology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005847:Geotrichosis / Q000209:etiology / Q000473:pathology; D006801:Humans; D007108:Immune Tolerance; D007223:Infant; D007231:Infant, Newborn; D008172:Lung Diseases, Fungal / Q000209:etiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000209:etiology / Q000473:pathology*