Sterols of Acanthamoeba culbertsoni strain A-1.
Two new sterols, stigmasta-5,7,22,25-tetraene-3 beta -ol (1) and stigmasta-5,7,14,22,25-pentaene-3 beta -ol (2), have been characterized along with ergosterol and 7-dehydrostigmasterol in the nonsaponifiable fraction of the total lipids extracted from trophozoites of Acanthamoeba culbertsoni strain A-1 (virulent strain). However, these sterols were found to be absent in the nonpathogenic strain C-7 of A. culbertsoni.
Mehdi
H
H
Central Drug Research Institute, Lucknow, India.
Garg
H S
HS
Garg
N K
NK
Bhakuni
D S
DS
D000048:Acanthamoeba / Q000032:analysis*; D000818:Animals; D004875:Ergosterol / Q000032:analysis; D013261:Sterols / Q000032:analysis*; D013265:Stigmasterol / Q000031:analogs & derivatives / Q000032:analysis
D013261:Sterols; C058991:stigmasta-5,7,22,25-tetraene-3-ol; C058993:stigmasta-5,7,14,22,25-pentaene-3-ol; C059013:7-dehydrostigmasterol; D013265:Stigmasterol; D004875:Ergosterol