title: Hepatic hemangioma: resection using hypothermic circulatory arrest in the newborn.
abstract: Hepatic hemangioma (hemangioendothelioma) is a benign vascular tumor with significant morbidity and mortality. Two newborn infants underwent partial hepatectomy for treatment of massive hepatic hemangioma, one with atrial septal defect and secondary congestive heart failure, and the other with symptomatic marked hepatomegaly. Cardiopulmonary bypass with induced deep hypothermic circulatory arrest was used in both patients in order to facilitate resection and prevent sudden massive blood loss. One infant also had closure of an atrial septal defect in addition to the partial hepatectomy. Both infants survived without complication and showed complete resolution of preoperative symptoms. This technique coupled with the use of fibrin glue is of value in infants with large hepatic hemangiomata and cardiac decompensation in the neonatal period.
authors.affiliation: Department of Surgery, Children's Mercy Hospital, Kansas City, MO 64108.
authors.forename: R D
authors.initials: RD
authors.lastname: Ranne
authors.forename: K W
authors.initials: KW
authors.lastname: Ashcraft
authors.forename: T M
authors.initials: TM
authors.lastname: Holder
authors.forename: R J
authors.initials: RJ
authors.lastname: Sharp
authors.forename: J P
authors.initials: JP
authors.lastname: Murphy
mesh_terms: D002315:Cardiopulmonary Bypass; D005260:Female; D006324:Heart Arrest, Induced; D006390:Hemangioendothelioma / Q000601:surgery; D006391:Hemangioma / Q000601:surgery*; D006392:Hemangioma, Cavernous / Q000601:surgery; D006801:Humans; D007036:Hypothermia, Induced; D007231:Infant, Newborn; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male