Interleukin 4 is at 5q31 and interleukin 6 is at 7p15.
DNA probes to the human interleukin 4 (IL4) and interleukin 6 (IL6) genes have been used for in situ hybridization to normal human chromosomes and Southern blot analysis of a series of mouse-human hybrid cell lines. IL4 maps to 5q31, the same location as IL5 and other haemopoietic growth factor genes. IL6 maps to 7p15. The significance of these locations is discussed.
Sutherland
G R
GR
Cytogenetics Unit, Adelaide Children's Hospital, North Adelaide, S.A., Australia.
Baker
E
E
Callen
D F
DF
Hyland
V J
VJ
Wong
G
G
Clark
S
S
Jones
S S
SS
Eglinton
L K
LK
Shannon
M F
MF
Lopez
A F
AF
D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D006822:Hybrid Cells; D015847:Interleukin-4; D015850:Interleukin-6; D007378:Interleukins / Q000235:genetics*; D009693:Nucleic Acid Hybridization
D015850:Interleukin-6; D007378:Interleukins; D015847:Interleukin-4