SPECT imaging of moyamoya disease using 99mTc-HM-PAO. Comparison with computed tomography findings.
99mTc-HM-PAO was used to evaluate regional cerebral blood flow in a 26-year-old woman with Moyamoya disease. This patient had an 18-month history of recurrent neurologic deficits and had angiographic evidence of Moyamoya disease. She had used oral contraceptives and cigarettes, but had no other risk factors for stroke. Single photon emission computed tomographic images showed bilateral and asymmetric reductions in blood flow to anterior and lateral brain regions. These findings correlated better with clinical symptomatology and suggested more extensive brain involvement than did computed tomography.
Mountz
J M
JM
Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0028.
Foster
N L
NL
Ackermann
R J
RJ
Bluemlein
L
L
Petry
N A
NA
Kuhl
D E
DE
D000328:Adult; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D009072:Moyamoya Disease / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D010091:Oximes; D013667:Technetium; D019690:Technetium Tc 99m Exametazime; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
D009942:Organometallic Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D013667:Technetium