title: Screening in mice of some medicinal plants used for analgesic purposes in the state of São Paulo.
abstract: Twelve medicinal plants used popularly for their reputed analgesic properties were tested in mice by the writhing and tail-flick methods. All extractions were made using 50% aqueous ethanol at low temperatures. The oral dose administered was always 1 g solids/kg. While several extracts showed a positive effect in one of the tests, significant effects in both tests were produced by Serjania communis only. Morphine and acetylsalicylic acid were used as reference drugs.
authors.affiliation: Depto. de Farmacologia, Escola Paulista de Medicina, São Paulo, Brazil.
authors.forename: L C
authors.initials: LC
authors.lastname: di Stasi
authors.forename: M
authors.initials: M
authors.lastname: Costa
authors.forename: S L
authors.initials: SL
authors.lastname: Mendaçolli
authors.forename: M
authors.initials: M
authors.lastname: Kirizawa
authors.forename: C
authors.initials: C
authors.lastname: Gomes
authors.forename: G
authors.initials: G
authors.lastname: Trolin
mesh_terms: D000005:Abdomen / Q000187:drug effects; D000700:Analgesics / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D001938:Brazil; D004353:Drug Evaluation, Preclinical; D000431:Ethanol; D005260:Female; D051379:Mice; D010146:Pain / Q000517:prevention & control; D010946:Plants, Medicinal / Q000032:analysis*; D013623:Tail / Q000187:drug effects; D013696:Temperature
chemical_list: D000700:Analgesics; D000431:Ethanol