Neonatal Guillain-Barré syndrome.
A term female infant had the clinical manifestations and accompanying electrophysiologic studies to fulfill the criteria of Guillain-Barré syndrome. At birth, she presented with generalized hypotonia, paucity of lower limb movements, and diminished muscle stretch reflexes. At 3 weeks of age, motor nerve conduction studies demonstrated evidence of demyelination and axonal involvement. Progressive clinical improvement was observed beginning at the age of 2 weeks with subsequent normalization of clinical examinations and nerve conduction studies. To our knowledge, this patient is the youngest reported with Guillain-Barré syndrome.
al-Qudah
A A
AA
Department of Pediatrics; Hospital for Sick Children, Toronto, Ontario, Canada.
Shahar
E
E
Logan
W J
WJ
Murphy
E G
EG
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000503:physiopathology*; D009046:Motor Neurons / Q000502:physiology; D011129:Polyradiculoneuropathy / Q000503:physiopathology*