Use of cyclodextrins in isotachophoresis. VI. Cyclodextrins as leading electrolyte additives for the separation of bile acids.
Cyclodextrins (CDs) and some of their methyl derivatives have been used for the optimization of the isotachophoretic separation of bile acids in aqueous electrolyte systems. The addition of heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin to the leading electrolyte proved useful for both the solubilization and the structural differentiation of the solutes studied and led to the successful separation of their mixtures. Other CDs tested, even if they gave a satisfactory solubilization effect, did not support the resolution of bile acid mixtures.
Snopek
J
J
Department of Analytical Chemistry, Charles University, Prague, Czechoslovakia.
Smolková-Keulemansová
E
E
Jelínek
I
I
Dohnal
J
J
Klinot
J
J
Klinotová
E
E
D001647:Bile Acids and Salts / Q000032:analysis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003505:Cyclodextrins; D003912:Dextrins; D004573:Electrolytes / Q000032:analysis; D004586:Electrophoresis; D012995:Solubility; D013213:Starch
D001647:Bile Acids and Salts; D003505:Cyclodextrins; D003912:Dextrins; D004573:Electrolytes; D013213:Starch