title: Comparative study of ceftriaxone and cefoperazone in the treatment of acute cholecystitis.
abstract: Forty patients with acute cholecystitis were divided into two randomized groups on the basis of the emergency antimicrobial therapy received, and were treated for a period of 5 days. The first group was given ceftriaxone (Rocephin), the second cefoperazone (Cefobis). This concomitant antimicrobial treatment of acute cholecystitis proved to be effective in 85% of the patients; 15% underwent 'à chaud' surgery on the 6th day because of a lack of response to the treatment. Ceftriaxone and cefoperazone proved to be equally effective. Use of ceftriaxone, however, was simpler (one injection a day) and the cost of treatment substantially lower.
authors.affiliation: Gastrointestinal Surgery Unit, Cantonal Hospital, University of Geneva, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Friedlender
authors.forename: P
authors.initials: P
authors.lastname: Meyer
authors.forename: M C
authors.initials: MC
authors.lastname: Marti
authors.forename: A
authors.initials: A
authors.lastname: Rohner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002438:Cefoperazone / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000627:therapeutic use*; D002764:Cholecystitis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged
chemical_list: D002443:Ceftriaxone; D002438:Cefoperazone