Chromatographic resolution of dipeptide enantiomers and diastereomers on chiral stationary phases from poly(L-leucine) or poly(L-phenylalanine).
Two types of chiral stationary phase, polymer-bonded and non-bonded, containing poly(L-leucine) and poly(L-phenylalanine) were prepared. These stationary phases gave higher enantioselectivity for the optical resolution of various derivatives of leucylphenylalanine methyl ester by liquid chromatography than did poly(L-alanine) and poly(L-glutamate).
Hirayama
C
C
Department of Applied Chemistry, Faculty of Engineering, Kumamoto University, Japan.
Ihara
H
H
Tanaka
K
K
D002853:Chromatography, Liquid; D004151:Dipeptides / Q000302:isolation & purification*; D010455:Peptides / Q000302:isolation & purification*; D013237:Stereoisomerism
D004151:Dipeptides; D010455:Peptides; C027819:polyleucine; C012001:polyphenylalanine