title: Reduction of nitroheterocyclic drugs by ascorbate and catecholamines: a possible mechanism for the neurotoxicity of nitroheterocyclic drugs.
authors.affiliation: Laboratory of Molecular Biophysics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709.
authors.forename: D N
authors.initials: DN
authors.lastname: Rao
authors.forename: R P
authors.initials: RP
authors.lastname: Mason
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D001711:Biotransformation; D002374:Catalase / Q000378:metabolism; D002395:Catecholamines / Q000378:metabolism*; D005609:Free Radicals; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008297:Male; D008795:Metronidazole / Q000378:metabolism*; D008920:Misonidazole / Q000378:metabolism*; D009498:Neurotoxins; D009582:Nitrofurantoin / Q000378:metabolism*; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D002395:Catecholamines; D005609:Free Radicals; D009498:Neurotoxins; D008795:Metronidazole; D008920:Misonidazole; D009582:Nitrofurantoin; D002374:Catalase; D013482:Superoxide Dismutase; D001205:Ascorbic Acid