title: [Intensive lymphoid hyperplasia of the peripancreatic ganglia and extrahepatic cholestasis in Sjögren's syndrome. Report of an unusual case].
abstract: The diagnostic triad of Sjögren's syndrome is keratoconjunctivitis sicca, xerostomia with o without salivary gland enlargement and the presence of a connective tissue disease usually rheumatoid arthritis). Is postulated an altered immune response of lymphocytes to ductal antigens glands and the result is an chronic inflammatory process with eventual fibrosis and hyposecretion of the affected glands. Lymphoproliferation is characteristic of the Sjögren's syndrome, the lungs, kidneys and salivary glands are the most affected: in this paper is presented the disease complex and not described of Sjögren's syndrome and intensive lymphoid hyperplasia of peripancreatic lymph nodes without chronic pancreatitis but with obstructive jaundice for involvement of the distal common bile duct. The percutaneous transhepatic cholangiography was suggestive of pancreatic disease and the surgery and the pathology certified the final diagnosis. A choledocho-enteric anastomosis was performed to remedy the extrahepatic cholestasis.
authors.affiliation: Departamento de Medicina, Hospital Nacional A Posadas, Buenos Aires, Argentina.
authors.forename: C L
authors.initials: CL
authors.lastname: Guma
authors.forename: J C
authors.initials: JC
authors.lastname: Sabio
authors.forename: J
authors.initials: J
authors.lastname: Torre
authors.forename: E
authors.initials: E
authors.lastname: Alvarez
mesh_terms: D002758:Cholangiography; D001651:Cholestasis, Extrahepatic / Q000209:etiology*; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology*; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000503:physiopathology*
vernacular_title: Intensa hiperplasia linfoide de ganglios peripancreáticos y colestasis extrahepática en un sindrome de Sjögren. Presentación de un caso inusual.