The genetic haptoglobin polymorphism: relevance of paternity assessment.
A practical method for haptoglobin subtyping is described utilizing fast sample preparation by means of batch adsorption to DEAE-cellulose and subsequent isoelectric focusing of reductively cleaved samples. The expanded haptoglobin polymorphism leads to an increase of the theoretical paternity exclusion rate to approximately 33%. Hence, the system appears to be highly attractive for paternity assessment.
Patzelt
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Institute of Forensic Medicine, Ernst Moritz Arndt Universität, Greifswald, German Democratic Republic.
Geserick
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Schröder
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D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D008297:Male; D010334:Paternity; D011110:Polymorphism, Genetic
D006242:Haptoglobins