[Use of dibunol and delagil in the treatment of acute pancreatitis].
The effect of Dibunol and Delagil on the course of experimental pancreatitis was studied in experiments in 80 rats and 36 dogs. The intravenous injection of the drugs was shown to decrease lethality of the animals. Control of biochemical parameters has revealed decreased activity of amylase, lipase, trypsin and malonic dialdehyde, normalized level of superlight luminescence of blood plasma. A good medical effect was obtained in 15 patients with acute pancreatitis.
Buianov
V M
VM
Stupin
I V
IV
Zheltikov
A N
AN
Sherstnev
M P
MP
D000208:Acute Disease; D000284:Administration, Oral; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage* / Q000494:pharmacology; D002084:Butylated Hydroxytoluene / Q000008:administration & dosage*; D002738:Chloroquine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D004285:Dogs; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007273:Injections, Intramuscular; D015227:Lipid Peroxidation / Q000187:drug effects; D008875:Middle Aged; D010195:Pancreatitis / Q000378:metabolism / Q000601:surgery*; D010740:Phospholipases / Q000037:antagonists & inhibitors; D011182:Postoperative Care; D051381:Rats
D000975:Antioxidants; D002084:Butylated Hydroxytoluene; C023676:chloroquine diphosphate; D002738:Chloroquine; D010740:Phospholipases
Primenenie dibunola i delagila v lechenii ostrogo pankreatita.