[Contingent negative variation and regional cerebral blood flow in senile dementia and cerebral aging].
Relationships between contingent negative variation (CNV) amplitude, regional cerebral blood flow (CBF), mini mental status examination score (MMSE) and reaction time (RT) have been studied in young subjects, non-demented old subjects and patients with primary degenerative senile dementia. Significant correlations have been found between CNV amplitude and global CBF, MMSE score and reaction time. Factorial analysis has shown 3 factors weighted respectively by MMSE and CNV, antero-posterior ratio fort left hemispheric CBF and age, and antero-posterior ratio for right hemispheric CBF and reaction time. Discriminant analysis has shown 2 discriminant functions differentiating young from old subjects with 90% accuracy and demented from non-demented patients with 75% accuracy.
Uytdenhoef
P
P
Service de neurologie, Hôpital civil, Charleroi, Belgique.
Depauw
Y
Y
Van Wettere
J P
JP
Godaux
E
E
Bernier
J
J
Jacquy
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001921:Brain / Q000254:growth & development / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D003704:Dementia / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
Etude de la variation contingente négative et du débit sanguin cérébral dans la démence sénile et le vieillissement cérébral.