Rhythmic digastric activity in the naloxone-treated decerebrate rabbit pup.
In decerebrate rabbit pups (greater than 1 and less than 7 days postnatal), exhibiting a digastric reflex with a latency of 20-25 ms, the administration of naloxone was followed by depression of the 25 ms latency reflex and the appearance of rhythmic EMG activity (10-18 Hz) with a latency of 45-90 ms. Such a frequency is not consistent with the normal rhythms of feeding but may relate to tooth grinding behaviour. In contrast, spontaneous rhythmic activity occurring after naloxone had a lower frequency, consistent with the normal rhythm of feeding.
Thexton
A J
AJ
Department of Physiology, UMDS (Guy's Campus), London, U.K.
McGarrick
J D
JD
Stone
T W
TW
D000818:Animals; D000831:Animals, Newborn; D004576:Electromyography; D008410:Masticatory Muscles / Q000502:physiology*; D009270:Naloxone / Q000494:pharmacology*; D011817:Rabbits; D012018:Reflex / Q000187:drug effects*
D009270:Naloxone