title: [Different forms of drug therapy for progressive sensorineural hearing loss in childhood].
abstract: Because of progressive sensorineural hearing loss 26 patients of the age of 2 to 19 years were treated for 10 days with infusions of prednisolone, pentoxifylline and piracetam. After this treatment improved, auditory thresholds were found in 58%. In comparison with a previous investigation (treatment with prednisolone and pentoxifylline except piacetam), no significant difference between these two methods of therapy was seen.
authors.affiliation: Klinik für Kommunikationsstörungen, Johannes-Gutenberg-Universität Mainz.
authors.forename: A
authors.initials: A
authors.lastname: Nickisch
authors.forename: M
authors.initials: M
authors.lastname: Heinemann
authors.forename: M
authors.initials: M
authors.lastname: Gross
mesh_terms: D000293:Adolescent; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000188:drug therapy*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D010431:Pentoxifylline / Q000627:therapeutic use*; D010889:Piracetam / Q000627:therapeutic use*; D011239:Prednisolone / Q000627:therapeutic use*; D011760:Pyrrolidinones / Q000627:therapeutic use*; D013805:Theobromine / Q000031:analogs & derivatives*
chemical_list: D011760:Pyrrolidinones; D011239:Prednisolone; D013805:Theobromine; D010431:Pentoxifylline; D010889:Piracetam
vernacular_title: Medikamentöse Therapieformen progredienter Schallempfindungsschwerhörigkeiten im Kindesalter.