Copper-manganese interactions concerning red-cell and plasma lipid peroxidation.
Manganese decreases the formation of methemoglobin and partially inhibits lipid peroxidation induced by copper in human erythrocytes. This is followed by delay in hemolysis. Manganese also reduces lipid peroxidation induced by copper in human plasma, these effects of manganese are stronger than those of zinc, a metal which is considered to have protective effects against free radical damage.
Fernandes
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AC
Institute of Physiological Chemistry, Faculty of Medicine, Lisbon, Portugal.
Manso
C F
CF
D000328:Adult; D002712:Chlorides; D003300:Copper / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D015227:Lipid Peroxidation / Q000187:drug effects*; D008054:Lipid Peroxides / Q000097:blood; D008345:Manganese / Q000494:pharmacology*; D017895:Manganese Compounds; D008706:Methemoglobin / Q000378:metabolism*
D002712:Chlorides; D008054:Lipid Peroxides; D017895:Manganese Compounds; D008345:Manganese; D003300:Copper; D008706:Methemoglobin; C025340:manganese chloride; C029892:cupric chloride