Torsade de pointes in a patient receiving intravenous vasopressin.
A patient experienced hypertension, bradycardia, QT prolongation, and multiple episodes of torsade de pointes while receiving an iv vasopressin infusion. The dysrhythmias were attributed to vasopressin, but may have been potentiated by hypomagnesemia. Upon vasopressin discontinuation, ECG findings returned to normal before magnesium supplementation. Vasopressin may contribute to the development of torsade de pointes.
Mauro
V F
VF
Department of Medicine, Medical College of Ohio, Toledo.
Bingle
J F
JF
Ginn
S M
SM
Jafri
F M
FM
D004932:Esophageal and Gastric Varices / Q000150:complications* / Q000628:therapy; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013610:Tachycardia / Q000209:etiology*; D014667:Vasopressins / Q000008:administration & dosage / Q000009:adverse effects*
D014667:Vasopressins