title: Control of massive vesical hemorrhage due to radiation cystitis with intravesical instillation of 15 (s) 15-methyl prostaglandin F2-alpha.
abstract: Intravesical instillation of 15 (s) 15-methyl prostaglandin F2-alpha (1 mg in 100 ml of normal saline on days 1 and 2, and 0.5 mg in 50 ml of normal saline on days 3 and 4) controlled massive vesical hemorrhage due to radiation cystitis in a 60-year female with carcinoma of uterine cervix. With the 1 mg dose, she developed severe bladder spasms and mild fever. No cardiac or respiratory side effect was observed.
authors.affiliation: Department of Urology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Hemal
authors.forename: S
authors.initials: S
authors.lastname: Vaidyanathan
authors.forename: A
authors.initials: A
authors.lastname: Sankaranarayanan
authors.forename: S
authors.initials: S
authors.lastname: Ayyagari
authors.forename: P L
authors.initials: PL
authors.lastname: Sharma
mesh_terms: D000368:Aged; D002260:Carboprost / Q000627:therapeutic use*; D003556:Cystitis / Q000150:complications* / Q000209:etiology; D005260:Female; D006417:Hematuria / Q000188:drug therapy / Q000209:etiology; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*; D001745:Urinary Bladder Diseases / Q000188:drug therapy* / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*
chemical_list: D011461:Prostaglandins F, Synthetic; D002260:Carboprost