Correlation of IgA2 serum levels in parent-offspring pairs.
IgA2 serum levels were measured by ELISA in 120 healthy subjects from 40 nuclear families (both parents and one offspring). No sex-associated difference was observed. Moreover, the IgA2 serum levels proved to be significantly correlated in parent-offspring pairs (r = 0.55; P less than 0.001), while there was no significant correlation in mother-father pairs of the same family. The data suggest that the serum level of the IgA2 subclass is genetically controlled.
De Benedictis
G
G
Department of Cell Biology, University of Calabria, Italy.
Rose
G
G
Brancati
C
C
D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000235:genetics / Q000276:immunology; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D007125:Immunogenetics; D007070:Immunoglobulin A / Q000235:genetics* / Q000378:metabolism; D008297:Male
D007070:Immunoglobulin A