title: Lymphadenopathy in chronic active hepatitis: CT observations.
abstract: CT scans were obtained in 17 patients who had biopsy-proved chronic active hepatitis in order to evaluate deteriorating liver function and clinical status. Lymphadenopathy in the porta hepatis and/or retroperitoneum was found in 11 patients (65%), and this was the only CT indication of significant hepatic disease in six patients (35%). In three of five patients who subsequently underwent immunosuppressive therapy, serial biopsy, and CT scanning, clinical and histologic improvement in the condition of the liver were accompanied by a reduction in lymph-node size on CT. These findings suggest that abdominal adenopathy is a frequent CT finding in patients who have chronic active hepatitis and might be a useful marker in monitoring immunotherapy.
authors.affiliation: Department of Radiology, Northwestern Memorial Hospital, Northwestern University Medical School, Chicago, IL 60611.
authors.forename: R M
authors.initials: RM
authors.lastname: Gore
authors.forename: R L
authors.initials: RL
authors.lastname: Vogelzang
authors.forename: A A
authors.initials: AA
authors.lastname: Nemcek
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006521:Hepatitis, Chronic / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011859:Radiography