Synthesis and mucolytic-expectorant activity of 3-mercapto-2 oxo 1-pyrrolidinyl acetic acid derivatives.
Coppi
G
G
Borella
F
F
Berti
M A
MA
Gatti
M T
MT
Comini
A
A
Dall'Asta
L
L
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005100:Expectorants / Q000138:chemical synthesis*; D005260:Female; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D011760:Pyrrolidinones / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains; D013438:Sulfhydryl Compounds / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D013552:Swine; D013876:Thiophenes / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity
D005100:Expectorants; D011760:Pyrrolidinones; D013438:Sulfhydryl Compounds; D013876:Thiophenes; C059774:3-mercapto-2-oxo-1-pyrrolidinyl acetic acid; C059775:3-(2-thienoylthio)-2-oxo-1-pyrrolidinyl acetic acid