The crystal structure of 2 beta,4 beta-cyclo-5 alpha-androstane-3 alpha,17 beta-diol diacetate.
An X-ray crystal structure determination was performed on 2 beta,4 beta-cyclo-5 alpha- and rostane-3 alpha,17 beta-diol diacetate. The parent diol, but not its 3 beta-epimer, had been shown to be an effective inhibitor of a 3 beta-hydroxysteroid dehydrogenase.
Orr
J C
JC
Faculty of Medicine, Memorial University of Newfoundland, Canada.
Newlands
M J
MJ
Gabe
E J
EJ
Charland
J P
JP
D015113:Androstane-3,17-diol / Q000031:analogs & derivatives* / Q000032:analysis; D000732:Androstanols / Q000031:analogs & derivatives*; D055598:Chemical Phenomena; D002621:Chemistry; D003461:Crystallography; D013237:Stereoisomerism
D000732:Androstanols; D015113:Androstane-3,17-diol; C059538:2,4-cycloandrostane-3,17-diol diacetate