Comparison of propofol and methohexitone as anaesthetic agents for electroconvulsive therapy.
Propofol was compared to methohexitone for induction of anaesthesia for electroconvulsive therapy. Seizures were significantly shorter after the use of propofol, in respect of both visible seizures and duration of cerebral electrical seizure activity. This suggests the possibility that additional treatments may be needed for the same clinical effect in psychiatric illness when propofol is used as the induction agent. Propofol was more effective than methohexitone at obtunding the hypertensive response to electroconvulsive therapy without causing significant hypotension.
Dwyer
R
R
Department of Anaesthetics, Craigavon Area Hospital, Armagh.
McCaughey
W
W
Lavery
J
J
McCarthy
G
G
Dundee
J W
JW
D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D000777:Anesthetics / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D004565:Electroconvulsive Therapy; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008723:Methohexital / Q000494:pharmacology; D008875:Middle Aged; D010636:Phenols / Q000494:pharmacology; D015742:Propofol; D013997:Time Factors
D000777:Anesthetics; D010636:Phenols; D008723:Methohexital; D015742:Propofol