title: [A histomorphometric study of normal iliac trabecular bones. Part II: Age changes and the values of MWT and related parameters].
abstract: The Mean Wall Thickness (MWT) of the trabecular packet and other related indices: number of osteocytic lacunae (N-0) and maximum number of birefringent lamellae (N-1) in the packet were measured in 142 normal Japanese subjects (male 55, female 87, mean age 44.8 yrs). MWT was obtained by the equation MWT = 2S/L, where S and L designate area and perimeter, respectively. The MWT, S, and L of the packets all decreased significantly after young adulthood. N-0 and N-1 also decreased significantly with age. In contrast, S/(N-0), which is the measure of the volume of the matrix being formed by a single osteoblast, did not change with age. Therefore, it may be concluded that BMU-leveled bone formation decreases with age probably due to the decreased number of osteoblasts which participate in forming a trabecular packet.
authors.affiliation: Department of Orthopaedic Surgery, University of Tsukuba, Ibaraki, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Ohno
authors.forename: T
authors.initials: T
authors.lastname: Yoshida
authors.forename: H
authors.initials: H
authors.lastname: Takematsu
authors.forename: Y
authors.initials: Y
authors.lastname: Nishizawa
authors.forename: H
authors.initials: H
authors.lastname: Amagai
authors.forename: S
authors.initials: S
authors.lastname: Yoshikawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology*; D002452:Cell Count; D002648:Child; D005260:Female; D006801:Humans; D007085:Ilium / Q000033:anatomy & histology* / Q000166:cytology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010006:Osteoblasts; D012737:Sex Factors; D013223:Statistics as Topic