Block of cardiac sodium-calcium exchange by mechanism-based inhibitors.
Kaczorowski
G J
GJ
Laboratory of Membrane Biochemistry and Biophysics, Merck Institute for Therapeutic Research, Rahway, New Jersey 07065.
Slaughter
R S
RS
Garcia
M L
ML
King
V F
VF
D000584:Amiloride / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D015764:Bepridil; D001665:Binding Sites; D001693:Biological Transport, Active / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D002121:Calcium Channel Blockers / Q000494:pharmacology; D002352:Carrier Proteins / Q000378:metabolism; D066298:In Vitro Techniques; D007474:Ion Exchange; D007700:Kinetics; D008565:Membrane Proteins / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism*; D011759:Pyrrolidines / Q000494:pharmacology; D012964:Sodium / Q000378:metabolism*; D019831:Sodium-Calcium Exchanger
D002121:Calcium Channel Blockers; D002352:Carrier Proteins; D008565:Membrane Proteins; D011759:Pyrrolidines; D019831:Sodium-Calcium Exchanger; D015764:Bepridil; D000584:Amiloride; D012964:Sodium; D002118:Calcium