title: Plasma 10-hydroxynortriptyline and therapeutic response in geriatric depression.
abstract: Geriatric inpatients with major depression received nortriptyline for 4 weeks. Plasma E-10-hydroxynortriptyline concentrations were correlated positively with residual Hamilton depression ratings and negatively with changes in ratings.
authors.affiliation: Department of Psychiatry, New York Hospital-Cornell Medical Center, NY.
authors.forename: R C
authors.initials: RC
authors.lastname: Young
authors.forename: G S
authors.initials: GS
authors.lastname: Alexopoulos
authors.forename: R
authors.initials: R
authors.lastname: Shindledecker
authors.forename: A K
authors.initials: AK
authors.lastname: Dhar
authors.forename: H
authors.initials: H
authors.lastname: Kutt
mesh_terms: D000368:Aged; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D009661:Nortriptyline / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: C013567:10-hydroxynortriptyline; D009661:Nortriptyline