[EEG changes in rats after subchronic exposure to ethanol].
EEG-investigations in rats were carried out 2 weeks after finishing a 3-month exposure scheme to ethanol (113 mmol/kg b.w., p.o., 5 times per week). We found pronounced disturbances of the sleep-wake behaviour as a reflection of a serious damage of the alertness-regulating system. The previously exposed animals did show disturbed vigilance and changes in the course and character of sleep, a reduction of power density in the alpha-, and an increase within the beta- and delta frequency bands of the EEG. The essential conclusions drawn from the experiment are comparable with EEG-changes in abstinent alcoholics, as reported in the literature.
Bergschicker
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R
Zentralinstitut für Arbeitsmedizin der DDR, Bereich Arbeitshygiene, Berlin.
Just
A
A
Hinz
G
G
Zöllner
I
I
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000502:physiology*; D004569:Electroencephalography; D000431:Ethanol / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values
D000431:Ethanol
EEG-Veränderungen der Ratte nach subchronischer Einwirkung von Ethanol.