Applications of fast atom bombardment and tandem mass spectrometry.
The application of fast atom bombardment combined with tandem mass spectrometry to the structure elucidation of carcinogen-modified oligonucleotides, glutathione, cysteine and N-acetyl cysteine conjugates of exogenous toxins and chemically modified peptides is described.
Tomer
K B
KB
Laboratory of Molecular Biophysics, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709.
Guenat
C
C
Dino
J J
JJ
Deterding
L J
LJ
D000111:Acetylcysteine / Q000032:analysis; D002273:Carcinogens / Q000032:analysis; D003545:Cysteine / Q000032:analysis; D005978:Glutathione / Q000032:analysis; D013058:Mass Spectrometry / Q000295:instrumentation*; D009841:Oligonucleotides / Q000032:analysis; D010455:Peptides / Q000032:analysis; D014118:Toxins, Biological / Q000032:analysis
D002273:Carcinogens; D009841:Oligonucleotides; D010455:Peptides; D014118:Toxins, Biological; D005978:Glutathione; D003545:Cysteine; D000111:Acetylcysteine