[Local anesthetics. 90. Asymmetric dibasic alkyl esters of alkoxyphenylcarbamic acids].
The synthesis of 24 compounds belonging to the group of dibasic substituted alkoxy phenyl carbamic acids is described. The compounds are characterized by relatively low acute toxicity and good local anaesthetic as well as antiarrhythmic activity.
Csöllei
J
J
Lehrstuhl für Pharmazeutische Chemie, Pharmazeutischen Fakultät der Komenský-Universität, Bratislava, CSSR.
Borovanský
A
A
Cizmárik
J
J
Svec
P
P
Racanská
E
E
Tumová
I
I
D000779:Anesthetics, Local / Q000138:chemical synthesis* / Q000633:toxicity; D000818:Animals; D002219:Carbamates / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D055598:Chemical Phenomena; D002621:Chemistry; D006168:Guinea Pigs; D007928:Lethal Dose 50; D051379:Mice
D000779:Anesthetics, Local; D002219:Carbamates
Untersuchungen an Lokalanästhetika. 90. Mitteilung: Asymmetrische dibasische Alkylester der Alkoxyphenylcarbamidsäuren.