Identification of amphetamine isomers by GC/IR/MS.
The methods of gas chromatography/Fourier transform infrared spectroscopy (GC/FTIR) and gas chromatography/infrared spectroscopy/mass spectrometry (GC/IR/MS) are evaluated for their ability to differentiate side chain isomers of amphetamine. It is found that absorption bands from 3000 to 2850 cm-1 and 900 to 650 cm-1 are most useful for differentiating the alkyl amines, while the bands from 1600 to 900 cm-1 are only useful for differentiating primary amines from the other substituted amines. The combination of GC/IR/MS is superior for differentiating these side chain isomers.
Duncan
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Hewlett-Packard, Scientific Instruments Division, Palo Alto, California 94303-0871.
Soine
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D000662:Amphetamines / Q000032:analysis*; D002849:Chromatography, Gas; D007536:Isomerism; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared
D000662:Amphetamines