[Stimulation of DNA synthesis in isolated nuclei of rat liver cells by neutral Mn-dependent DNase of chromatin].
It was demonstrated that neutral Mn-dependent DNAase from rat liver chromatin stimulates the incorporation of labeled precursors of DNA into high molecular weight fractions of isolated nuclear DNA. The effects of DNA-polymerase inhibitors and the properties of DNA synthesis products suggest that neutral Mn-dependent DNAase can induce replicative synthesis of DNA in the nuclei of normal and regenerating rat liver.
Vinter
V G
VG
Askarova
A N
AN
Zotkina
N L
NL
Khamidullina
N G
NG
Shliankevich
M A
MA
D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D002843:Chromatin / Q000201:enzymology*; D004247:DNA / Q000096:biosynthesis*; D003851:Deoxyribonucleases / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D008345:Manganese / Q000378:metabolism; D051381:Rats
D002843:Chromatin; D008345:Manganese; D004247:DNA; D003851:Deoxyribonucleases
Stimuliatsiia sinteza DNK v izolirovannykh iadrakh kletok pecheni krys netral'noĭ Mn-zavisimoĭ DNKazoĭ khromatina.