title: Optic nerve regeneration--new aspects.
abstract: Injury to the optic nerve and its environment provokes a process of degeneration that leads to a degenerative process resulting in an irreversible loss of visual function. We succeeded in stimulating regeneration in injured optic nerves of adult rabbits. The stimulus to regeneration was achieved by implanting in injured optic nerves of adult rabbits substances originating from growing (regenerating) optic nerves of fish or developing optic nerves of neonatal rabbits, and by delaying the degenerative process by irradiating the injured optic nerve with a low energy laser. The effect was manifested by abundant growth of new fibers across the injury site and by other manifestation of regeneration characteristics.
authors.affiliation: Maurice and Gabriela Goldschleger Eye Research Institute, Chaim Sheba Medical Center Tel-Hashomer, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Solomon
authors.forename: M
authors.initials: M
authors.lastname: Belkin
authors.forename: A
authors.initials: A
authors.lastname: Harel
authors.forename: M
authors.initials: M
authors.lastname: Rosner
authors.forename: S
authors.initials: S
authors.lastname: Benbasat
authors.forename: V
authors.initials: V
authors.lastname: Lavie
authors.forename: M
authors.initials: M
authors.lastname: Erlich
authors.forename: M
authors.initials: M
authors.lastname: Schwartz
mesh_terms: D000818:Animals; D005131:Eye Injuries / Q000503:physiopathology; D006133:Growth Substances; D009416:Nerve Regeneration; D009900:Optic Nerve / Q000502:physiology*; D011817:Rabbits
chemical_list: D006133:Growth Substances