title: Cardiac arrest--a manifestation of 5-fluorouracil cardiotoxicity.
abstract: We report a case of cardiac arrest occurring during an infusion of 5-fluorouracil where electrocardiograms suggested coronary artery spasm as the underlying event. Treatment with vasodilators and diltiazem, proved effective. This clinical presentation of 5-fluorouracil cardiotoxicity has not previously been described.
authors.affiliation: Department of Medical Oncology, Sir Charles Gairdner Hospital, Nedlands, WA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Millward
authors.forename: V
authors.initials: V
authors.lastname: Ganju
authors.forename: M
authors.initials: M
authors.lastname: Buck
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D004562:Electrocardiography; D005472:Fluorouracil / Q000009:adverse effects*; D006321:Heart / Q000187:drug effects*; D006323:Heart Arrest / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy
chemical_list: D005472:Fluorouracil