[Regulation of synthesis of virus-specific RNA in cells infected with influenza virus].
Interrelationships between the level of protein synthesis and the pattern of virus-specific transcription in influenza virus-infected cells have been studied with the use of a wide range of concentrations of a protein synthesis inhibitor (cycloheximide). The obtained data reveal a predominant stimulation of the transcription for some viral genes by partial suppression of protein synthesis. The data also suggest the existence of cRNA (full transcripts) synthesis regulation, in addition to the regulation of vRNA and mRNA synthesis described earlier.
Varich
N L
NL
Gubareva
L V
LV
Kaverin
N V
NV
D000818:Animals; D002642:Chick Embryo; D003513:Cycloheximide / Q000494:pharmacology; D009980:Influenza A virus / Q000235:genetics* / Q000502:physiology; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D012367:RNA, Viral / Q000096:biosynthesis* / Q000235:genetics; D014158:Transcription, Genetic; D014764:Viral Proteins / Q000096:biosynthesis; D014779:Virus Replication
D012333:RNA, Messenger; D012367:RNA, Viral; D014764:Viral Proteins; D003513:Cycloheximide
Reguliatsiia sinteza virusspetsificheskikh RNK v kletkakh, zarazhennykh virusom grippa.