Cycling cytoplasmic factors that promote mitosis in the cultured 2-cell mouse embryo.
A cytoplasmic component(s), previously shown to rescue the 'blocked' 2-cell mouse embryo in vitro, has been demonstrated to peak in activity during the transition between G2 and M phase and decline thereafter. The possible significance of this component(s) in the regulation of cleavage of the cultured mouse embryo is discussed.
Pratt
H P
HP
Department of Anatomy, Cambridge, UK.
Muggleton-Harris
A L
AL
D000818:Animals; D002478:Cells, Cultured; D002970:Cleavage Stage, Ovum; D003593:Cytoplasm / Q000502:physiology*; D004622:Embryo, Mammalian / Q000502:physiology* / Q000648:ultrastructure; D051379:Mice; D008854:Microscopy, Electron; D008938:Mitosis