title: Retrograde transport of [3H]-D-aspartate label by cochlear and vestibular efferent neurons.
abstract: [3H]-D-aspartic acid was injected into the inner ear of rats. After a six hour survival time, labeled cells were found at all locations known to contain efferent cochlear or vestibular neurons. Most labeled neurons were found in the ipsilateral lateral superior olivary nucleus (LSO), although both ventral nuclei of the trapezoid body (VTB), group E, and the caudal pontine reticular nucleus (CPR) just adjacent to the ascending limb of the facial nerve also contained labeled cells. Because not all efferent neurons in the rat could be previously shown to be cholinergic, aspartate and glutamate are efferent transmitter candidates.
authors.affiliation: Division of Otolaryngology, University of British Columbia, Vancouver, Canada.
authors.forename: D W
authors.initials: DW
authors.lastname: Schwarz
authors.forename: I E
authors.initials: IE
authors.lastname: Schwarz
mesh_terms: D000818:Animals; D001224:Aspartic Acid; D003051:Cochlea / Q000294:innervation*; D009434:Neural Pathways / Q000033:anatomy & histology; D009476:Neurons, Efferent / Q000166:cytology*; D009847:Olivary Nucleus / Q000033:anatomy & histology; D051381:Rats; D014316:Tritium; D014722:Vestibule, Labyrinth / Q000294:innervation*
chemical_list: D014316:Tritium; D001224:Aspartic Acid