title: The outcome of pregnancy complicated by severe asthma.
abstract: Eighty pregnancies in 73 gravidas with severe asthma who required inhaled and/or systemic corticosteroids were reported in an attempt to define the effects of asthma and its treatment on the outcome of pregnancy. No maternal deaths occurred. Infants delivered from gravidas who experienced at least one episode of status asthmaticus during gestation had decreased birth weights (p = 0.03) compared with infants delivered from gravidas who did not require emergency therapy or develop status asthmaticus. The data confirm the importance of maintaining gravidas with severe asthma as free from symptoms and signs of asthma as possible.
authors.affiliation: Department of Medicine, Northwestern University Medical School, Chicago, Illinois 60611.
authors.forename: P A
authors.initials: PA
authors.lastname: Greenberger
authors.forename: R
authors.initials: R
authors.lastname: Patterson
mesh_terms: D000328:Adult; D001249:Asthma / Q000150:complications*; D004630:Emergencies; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D011446:Prospective Studies; D013224:Status Asthmaticus / Q000150:complications* / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids