Direct resolution of the stereoisomers of leucovorin and 5-methyltetrahydrofolate using a bovine serum albumin high-performance liquid chromatographic chiral stationary phase coupled to an achiral phenyl column.
Wainer
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IW
Pharmaceutical Division, St. Jude Children's Research Hospital, Memphis, TN 38101.
Stiffin
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RM
D000818:Animals; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D002955:Leucovorin / Q000097:blood*; D012710:Serum Albumin, Bovine; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism; D013763:Tetrahydrofolates / Q000097:blood*
D013763:Tetrahydrofolates; D012710:Serum Albumin, Bovine; D002955:Leucovorin; C005984:5-methyltetrahydrofolate