title: [Clinical evaluation of osteocalcin in sera of the patients with neoplasms of bone].
abstract: The clinical significance of osteocalcin in sera of bone tumors were measured in sera of various kinds of bone tumors. The levels of osteocalcin were higher in bone tumors than those in normal subjects. Serum osteocalcin levels in hypercalcemic groups of bone metastasis and myeloma showed a remarkable increase in a parallelism with serum ALP and LDH levels. These results suggested to be directly or indirectly activated on osteoblast by bone tumors and to be synthesized osteocalcin in osteoblast.
authors.affiliation: Department of Radiology, Wakayama Medical College, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Torizumi
authors.forename: A
authors.initials: A
authors.lastname: Ueyoshi
authors.forename: M
authors.initials: M
authors.lastname: Yasui
authors.forename: E
authors.initials: E
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Okamoto
authors.forename: T
authors.initials: T
authors.lastname: Tuda
authors.forename: K
authors.initials: K
authors.lastname: Ota
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood; D001859:Bone Neoplasms / Q000097:blood*; D002135:Calcium-Binding Proteins / Q000097:blood*; D005260:Female; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D015675:Osteocalcin
chemical_list: D002135:Calcium-Binding Proteins; D015675:Osteocalcin; D007770:L-Lactate Dehydrogenase; D000469:Alkaline Phosphatase