title: Acute renal failure due to profound haemolysis--an unusual complication of cusp rupture in cardiac bioprostheses.
abstract: Haemolysis due to prosthetic cardiac valves is well documented in the literature, with an increased incidence in mechanical prostheses as compared to bioprostheses. We report this unusual complication in two patients who developed profound haemolysis rapidly resulting in acute renal failure following cusp rupture in mitral Ionescu-Shiley valves. One of the patients developed irreversible renal failure in spite of successful reoperation, while renal function normalized in the second case.
authors.affiliation: Department of Cardiac Surgery, Northern General Hospital, Sheffield, UK.
authors.forename: P B
authors.initials: PB
authors.lastname: Rajesh
authors.forename: J J
authors.initials: JJ
authors.lastname: Goiti
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D000368:Aged; D001705:Bioprosthesis / Q000009:adverse effects*; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006461:Hemolysis; D006801:Humans; D008297:Male; D011475:Prosthesis Failure; D012086:Reoperation