Endogenous digoxin-like immunoreactive substance in patients undergoing coronary surgery. Preliminary report.
Perioperative digoxin concentrations were measured in 20 unselected adult patients undergoing coronary surgery. None of the patients were receiving treatment with digoxin. A digoxin-like immunoreactive substance was found in 16 patients postoperatively. This substance, if pharmacologically active, may have important clinical implications in the management of patients after open heart surgery.
Nashef
S A
SA
Department of Cardiac Surgery, Western Infirmary, Glasgow, Scotland.
Kirk
A J
AJ
Brewster
N
N
Louden
I
I
Percy-Robb
I W
IW
Bain
W H
WH
D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000378:metabolism*; D002298:Cardenolides; D001026:Coronary Artery Bypass; D004077:Digoxin; D005260:Female; D015200:Fluoroimmunoassay; D006801:Humans; D008297:Male; D008875:Middle Aged; D012503:Saponins
D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin