[Two color analysis of peripheral lymphocyte subsets in patients with cancers during and after radiotherapy].
Lymphocyte subsets of peripheral blood in patients with cancers were analyzed through two color analysis using FCM. Leu-2/Leu-3 and Leu-2+15+/Leu-8-3+ were compared during radiotherapy and periods of follow up in cases with uterine cervical ca. and lung ca. They did not show similar tendencies but just a opposite one in some cases. Both of them, on the other hand, did not appear to be related with the prognosis of patients. However, CTL and NK (potent) did show a relevance with it through the period of follow up. They might be indices which allow to predict the clinical course of Patients with cancers. Further study is now in progress.
Nakatsugawa
S
S
Dept. Radiol., Fukui Medical School.
Kimoto
T
T
Takahashi
N
N
Kimura
H
H
Takabatake
M
M
Yamada
H
H
Maeda
M
M
Yamamoto
K
K
Suto
Y
Y
Kimura
K
K
D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000276:immunology; D008175:Lung Neoplasms / Q000276:immunology / Q000532:radiotherapy* / Q000601:surgery; D008875:Middle Aged; D011379:Prognosis; D013601:T-Lymphocytes / Q000145:classification*; D002583:Uterine Cervical Neoplasms / Q000276:immunology / Q000532:radiotherapy* / Q000601:surgery