title: A double-crossover trial comparing the effects of topical carteolol and placebo on intraocular pressure.
abstract: The effect of topical carteolol 2% on the intraocular pressures of 12 patients suspected of having glaucoma was measured in a double-crossover trial of six weeks' duration. Carteolol produced a significant reduction in intraocular pressure (p less than or equal to 0.001), when compared with placebo. This represented reductions of 11% and 14%, after one and two weeks of treatment.
authors.affiliation: Department of Ophthalmology, University Hospital of Wales.
authors.forename: G R
authors.initials: GR
authors.lastname: Duff
authors.forename: P A
authors.initials: PA
authors.lastname: Graham
mesh_terms: D000287:Administration, Topical; D002354:Carteolol / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009798:Ocular Hypertension / Q000188:drug therapy*; D011412:Propanolamines / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D011412:Propanolamines; D002354:Carteolol