title: A case of Creutzfeldt-Jakob disease related to familial retinitis pigmentosa patients.
abstract: Similarities between serological alterations and retinal degeneration occurring in natural and experimental CJD and in some forms of human retinal degeneration have recently been reported. In the present paper a family from an areal focal accumulation of CJD in Central Slovakia with 1 histopathologically verified case of Creutzfeldt-Jakob disease and 2 case of retinitis pigmentosa is described. Neuropathological and epidemiological data obtained in investigated patients are discussed from the point of view of a possible relationship between the slow virus infections caused by unconventional agents and degenerative disease affecting the ocular system.
authors.affiliation: Research Institute of Preventive Medicine, Bratislava, Czechoslovakia.
authors.forename: E
authors.initials: E
authors.lastname: Mitrovà
mesh_terms: D000328:Adult; D007562:Creutzfeldt-Jakob Syndrome / Q000209:etiology* / Q000235:genetics; D004198:Disease Susceptibility; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012174:Retinitis Pigmentosa / Q000209:etiology / Q000235:genetics*