title: Non-obstructive kidney transplant dysfunction: magnetic resonance evaluation.
abstract: The value of magnetic resonance imaging in the differential diagnosis of non-obstructive dysfunction of renal allografts was studied in a series of 58 examinations at 0.5 T. Four parameters were evaluated: the corticomedullary differentiation; the relative thickness of the cortex; the evolution, with echo number, of the relative signal intensities of kidney parenchyma and adjacent fatty tissue on images generated by a long time to repeat multiecho sequence; and the proximal vascularization. The loss of corticomedullary differentiation is the major finding in acute rejection, but it is not specific as it is also observed in chronic rejection and in the much rarer acute glomerulonephritis. Thickening of the cortex is helpful for the detection of rejected transplants with visible corticomedullary delineation (26% of the cases). Uncomplicated acute tubular necrosis appears as a normal transplant.
authors.affiliation: Department of Radiology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.
authors.forename: D
authors.initials: D
authors.lastname: Van Gansbeke
authors.forename: C
authors.initials: C
authors.lastname: Segebarth
authors.forename: C
authors.initials: C
authors.lastname: Toussaint
authors.forename: C
authors.initials: C
authors.lastname: Matos
authors.forename: P A
authors.initials: PA
authors.lastname: Gevenois
authors.forename: P
authors.initials: P
authors.lastname: Kinnaert
authors.forename: J
authors.initials: J
authors.lastname: Struyven
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006084:Graft Rejection; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000503:physiopathology; D016030:Kidney Transplantation; D007683:Kidney Tubular Necrosis, Acute / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged