title: Treatment of common warts with high-potency (26%) salicylic acid.
abstract: Treatment of common warts with topical keratolytic solutions is generally estimated to result in cure rates of 60% to 80% in 12 weeks. Problems with keratolytic solutions include irritation of surrounding normal skin and poor patient compliance. A product containing 26% salicylic acid in a novel polyacrylic vehicle was evaluated in 27 patients and found to cure or provide much improvement in 22 (81%) after only two weeks of treatment. This rapid response was accompanied by a low incidence of irritation. The results of this study suggest that high-potency salicylic acid promotes prompt resolution of warts, which may enhance patient compliance.
authors.affiliation: Department of Dermatology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: L C
authors.initials: LC
authors.lastname: Parish
authors.forename: E
authors.initials: E
authors.lastname: Monroe
authors.forename: I H
authors.initials: IH
authors.lastname: Rex
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D014677:Pharmaceutical Vehicles; D012459:Salicylates / Q000008:administration & dosage / Q000627:therapeutic use*; D014860:Warts / Q000188:drug therapy*
chemical_list: D014677:Pharmaceutical Vehicles; D012459:Salicylates