[Interferon activation of the production of a factor increasing the bactericidal properties of mouse macrophages].
It has been established that the administration of homologous interferon to mice activates the production by splenocytes of a factor increasing the bactericidal properties of macrophages in the peritoneal exudate. The activation effect was dose-dependent. The maximum production was noted on day 3 after the injection of interferon, type I, or its inducers. Cell-producers of the factor are mainly lymphocytes.
Ganova
L A
LA
Fil'chakov
I V
IV
Spivak
N Ia
NIa
Ivanenko
V K
VK
Zueva
V S
VS
D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D001419:Bacteria / Q000276:immunology*; D007369:Interferon Inducers / Q000494:pharmacology; D007370:Interferon Type I / Q000494:pharmacology*; D008222:Lymphokines / Q000096:biosynthesis*; D016215:Macrophage-Activating Factors; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D010587:Phagocytosis
D007369:Interferon Inducers; D007370:Interferon Type I; D008222:Lymphokines; D016215:Macrophage-Activating Factors
Aktivatsiia interferonom vyrabotki faktora, povyshaiushchego bakteritsidnost' makrofagov mysheĭ.