title: Congenital atresia and stenosis of the duodenum: the impact of a prenatal diagnosis.
abstract: This review was undertaken to determine the effects of prenatal diagnosis, on the basis of ultrasonographic evidence, of a duodenal obstruction on the care and morbidity of the newborn infant. The records of 46 cases of either atresia or stenosis of the small bowel in infants treated during the last six years in a tertiary perinatal center were reviewed retrospectively. A prenatal fetal diagnosis of obstruction was made in 13 patients (12 obstructions located in the duodenum and one in the jejunum). The mean gestational age at prenatal diagnosis was 33.7 weeks (range 27 to 37 weeks). The course of those infants with the prenatal diagnosis made by ultrasound was compared with that of those infants in whom the diagnosis was established after the onset of symptoms of obstruction appeared. Such a prenatal diagnosis resulted in earlier surgical intervention (1.8 versus 3.9 days). Metabolic complications secondary to repeated vomiting were found to be less frequent. The expectant mother in whom such a fetal prenatal diagnosis has been made can be transported to a tertiary level perinatal center where neonatal and specialized surgical expertise are available. After birth, the infant can undergo immediate operation without being separated from its mother.
authors.affiliation: Perinatal Service of Hôpital Sainte-Justine, Department of Pediatrics, Université de Montréal, Quebec, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Miro
authors.forename: H
authors.initials: H
authors.lastname: Bard
mesh_terms: D000015:Abnormalities, Multiple; D000367:Age Factors; D004380:Duodenal Obstruction / Q000150:complications / Q000151:congenital* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D008659:Metabolic Diseases / Q000209:etiology; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography