title: [Comparative epicutaneous study on allergy to mild-fibrosing agents].
abstract: In connection with clinical observations and literature data about allergic manifestations in the oral cavity in the treatment of periodontal pockets with mild-fibrosing agents, we performed a comparative epicutaneous study on the preparations most often used in our country: Phytodont, maraslavin, zemisvet and preparation P. The method of Jadahsson and Block was used in patients with manifested periodontosis. Positive allergic tests with zemisvet and preparation P have not been established so far, whereas they were 5.71% with maraslavin and 8.57%--with phytodont. That provided grounds to recommend the fibrosing therapy in the single courses to be performed with various mild-fibrosing agents so as to reduce the possibilities of sendibilization. In the presence of data about drug allergy, the patients should be tested for allergy to the respective mild-fibrosing agents prior to the fibrosing therapy.
authors.forename: M
authors.initials: M
authors.lastname: Semerdzieva
authors.forename: K
authors.initials: K
authors.lastname: Gogova
mesh_terms: D004342:Drug Hypersensitivity; D006801:Humans; D010514:Periodontal Pocket / Q000188:drug therapy*; D010518:Periodontitis / Q000188:drug therapy*; D012882:Skin Tests
vernacular_title: Sravnitelno epikutanno izsledvane za alergiia kum mekofibrozirashti sredstva.