Structure of salicylaldehyde thiosemicarbazone.
C8H9N3OS, monoclinic, C2/c, a = 14.206 (3), b = 14.244 (4), c = 10.457 (4) A, beta = 116.18(2) degrees, V = 1898.9 (8) A3, Z = 8, Dm = 1.387, D chi = 1.366 g cm-3, lambda(Mo K alpha) = 0.71069 A, mu = 2.90 cm-1, F(000) = 816.0, T = 298 K, final R = 0.0429 for 1322 observed reflections. The S and hydrazinic N atoms lie trans. The lowering of antibacterial activity compared to that of 4-phenylthiosemicarbazide may be correlated with the decrease in negative charge on the hydrazinic N atom. The crystal structure is stabilized by hydrogen bonding, stacking interactions and van der Waals forces.
Chattopadhyay
D
D
Crystallography and Molecular Biology Division, Saha Institute of Nuclear Physics, Calcutta, India.
Mazumdar
S K
SK
Banerjee
T
T
Ghosh
S
S
Mak
T C
TC
D000447:Aldehydes; D000890:Anti-Infective Agents; D008958:Models, Molecular; D008968:Molecular Conformation; D012984:Software; D013882:Thiosemicarbazones; D014961:X-Ray Diffraction / Q000379:methods
D000447:Aldehydes; D000890:Anti-Infective Agents; D013882:Thiosemicarbazones; C062542:salicylaldehyde thiosemicarbazone