Serum prostacyclin binding and half-life in the umbilical circulation.
Serum prostacyclin binding and half-life was measured in twenty pairs of maternal and umbilical venous samples and in twenty non-pregnant controls. When compared to non-pregnant values both umbilical and maternal samples demonstrated significantly lower albumin concentrations, percentage of prostacyclin binding and shorter prostacyclin half-life.
O'Brien
W F
WF
Department of Obstetrics and Gynecology, University of South Florida, College of Medicine, Tampa 33612.
Knuppel
R A
RA
Saba
H I
HI
Benoit
R
R
Bruce
A
A
D011464:Epoprostenol / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006207:Half-Life; D006801:Humans; D011247:Pregnancy; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism; D012712:Serum Globulins / Q000378:metabolism; D014471:Umbilical Veins
D012709:Serum Albumin; D012712:Serum Globulins; D011464:Epoprostenol