title: High-dose weekly oral leucovorin and 5-fluorouracil in previously untreated patients with advanced colorectal carcinoma: a phase I study.
authors.affiliation: Cleveland Metropolitan General Hospital, Ohio 44109.
authors.forename: J D
authors.initials: JD
authors.lastname: Hines
authors.forename: D J
authors.initials: DJ
authors.lastname: Adelstein
authors.forename: J L
authors.initials: JL
authors.lastname: Spiess
authors.forename: S G
authors.initials: SG
authors.lastname: Carter
authors.forename: J E
authors.initials: JE
authors.lastname: Trey
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use / Q000633:toxicity*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004341:Drug Evaluation; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis
chemical_list: D002955:Leucovorin; D005472:Fluorouracil