Chemical and biological properties of indole glucosinolates (glucobrassicins): a review.
Glucosinolates are a group of secondary products commonly, but not exclusively, found in plants of the family Cruciferae. They give rise, upon enzymic hydrolysis, to a range of volatile, pungent and physiologically active compounds. Recently, particular attention has been focused upon those that are trytophan-derived--the indole glucosinolates (glucobrassicins). When chemically or enzymically hydrolysed these compounds give rise to a range of involatile indole compounds which have been implicated in the anti-carcinogenic and mixed-function-oxidase stimulatory activities of brassica vegetables. This review details the chemical and physiological properties of indole glucosinolates and their products and suggests possible areas for future research.
McDanell
R
R
Department of Toxicology, Rayne Institute, University College London.
McLean
A E
AE
Hanley
A B
AB
Heaney
R K
RK
Fenwick
G R
GR
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005961:Glucosinolates / Q000032:analysis / Q000378:metabolism / Q000494:pharmacology; D006868:Hydrolysis; D007211:Indoles; D010084:Oxidation-Reduction; D004364:Pharmaceutical Preparations / Q000378:metabolism; D051381:Rats; D013865:Thioglycosides / Q000032:analysis / Q000378:metabolism / Q000494:pharmacology
D005961:Glucosinolates; D007211:Indoles; D004364:Pharmaceutical Preparations; D013865:Thioglycosides; C048308:glucobrassicin