Effect of immunoglobulin preparation on course of AIDS-related complex (ARC).
Relatively low dose treatment (150 mg/kg, once per two weeks) of a intravenous immunoglobulin (IVI) preparation has shown a beneficial effect on CD4/CD8 ratio and CD4 cell counts in two patients with AIDS-related complex (ARC). Since ARC generally progresses to AIDS with a marked reduction of CD4 cells or a marked inversion of CD4/CD8 ratio, this type of IVI treatment seems to be effective for obstructing or at least delaying the progression from ARC to AIDS.
Ohno
T
T
Department of Internal Medicine, Faculty of Medicine, Kyoto University.
Kanoh
T
T
Uchino
H
H
Harada
S
S
D000386:AIDS-Related Complex / Q000628:therapy*; D000328:Adult; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D006801:Humans; D007116:Immunization, Passive; D007275:Injections, Intravenous
D000945:Antigens, Differentiation, T-Lymphocyte