title: 'Toxic strep syndrome'. A manifestation of group A streptococcal infection.
abstract: Three patients presented with multisystem disease that shared many of the features of toxic shock syndrome. Bacteriologic and serologic evidence strongly suggested that group A beta-hemolytic Streptococcus had caused the illnesses. Group A streptococcal infection may be an underdiagnosed cause of a toxic streptococcal syndrome, a syndrome of multisystem disease apparently mediated by toxins.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, University of Massachusetts Medical School, Worcester.
authors.forename: T
authors.initials: T
authors.lastname: Bartter
authors.forename: A
authors.initials: A
authors.lastname: Dascal
authors.forename: K
authors.initials: K
authors.lastname: Carroll
authors.forename: F J
authors.initials: FJ
authors.lastname: Curley
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001426:Bacterial Proteins; D005098:Exotoxins; D005260:Female; D006801:Humans; D008565:Membrane Proteins; D008875:Middle Aged; D012772:Shock, Septic / Q000209:etiology*; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D013297:Streptococcus pyogenes / Q000472:pathogenicity
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D005098:Exotoxins; D008565:Membrane Proteins; C117980:SpeA protein, Streptococcus pyogenes; C027951:erythrogenic toxin