title: The cellular effects of estrogens on neuroendocrine tissues.
abstract: Estrogen action on sensitive neurons in the rat diencephalon has been studied by morphologic techniques; evidence of estrogen action at every level is presented, including tracts, cells, circuitry and subcellular organelles. The demonstration in the arcuate nucleus of estrogen-induced synaptic remodelling, estrogen-induced postsynaptic membrane phenotypes, changes in intracellular membranes and rapid estrogen actions on neuronal endo-exocytosis indicates that cellular estrogen actions may underlie the neuronal control of reproduction.
authors.affiliation: Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06510.
authors.forename: F
authors.initials: F
authors.lastname: Naftolin
authors.forename: N J
authors.initials: NJ
authors.lastname: MacLusky
authors.forename: C Z
authors.initials: CZ
authors.lastname: Leranth
authors.forename: H S
authors.initials: HS
authors.lastname: Sakamoto
authors.forename: L M
authors.initials: LM
authors.lastname: Garcia-Segura
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000502:physiology*; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D008297:Male; D008954:Models, Biological; D009474:Neurons / Q000502:physiology; D009490:Neurosecretory Systems / Q000187:drug effects / Q000502:physiology*
chemical_list: D004967:Estrogens