title: Benefits of carotid patching: a randomized study.
abstract: Advocates of carotid artery patching claim a reduced incidence of recurrent stenosis after endarterectomy. A prospective study was undertaken to determine its value with random selection between primary closure and saphenous vein patching. A consecutive series of 129 carotid endarterectomies was evaluated by duplex scanning at 3, 6, and 12 months after operation. Intravenous digital subtraction angiography (DSA) was performed in the first postoperative days for control of the surgical technique and after 1 year to serve as a reference for the duplex scanning. Sixty-two patients were selected to have primary closure and 67 were chosen for the patching technique. Both groups were identical with regard to risk factors (mean age 63 years, 74% were men, 57% had hypertension, 41% had coronary disease, 37% had peripheral arterial disease, and 9% had diabetes mellitus), side of operation (55% left), symptoms (18% were asymptomatic), and postoperative DSA (81% were normal, 17% had residual lesions, and 2% had occlusions). A complete 1-year follow-up was obtained in 105 cases (81%); duplex scanning showed recurrent stenosis of more than 50% in 12 cases (11%). This was significantly higher after primary closure (10 of 48 patients = 21%) compared with patch closure (2 of 57 = 3.5%; p = 0.006) and also in women (6 of 25 = 24%) compared with men (6 of 80 = 7.5%; p = 0.03). Recurrent stenosis was present in 6 of 11 women with primary closure (55%), 4 of 37 men with primary closure (11%), 2 of 43 men with patching (5%), and none of 14 women with patch closure (0%).(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Surgery, St. Antonius Hospital, Nieuwegein, The Netherlands.
authors.forename: B C
authors.initials: BC
authors.lastname: Eikelboom
authors.forename: R G
authors.initials: RG
authors.lastname: Ackerstaff
authors.forename: H
authors.initials: H
authors.lastname: Hoeneveld
authors.forename: J W
authors.initials: JW
authors.lastname: Ludwig
authors.forename: C
authors.initials: C
authors.lastname: Teeuwen
authors.forename: F E
authors.initials: FE
authors.lastname: Vermeulen
authors.forename: R J
authors.initials: RJ
authors.lastname: Welten
mesh_terms: D000792:Angiography / Q000379:methods; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000601:surgery*; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging / Q000601:surgery; D002986:Clinical Trials as Topic; D003251:Constriction, Pathologic; D004691:Endarterectomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D011856:Radiographic Image Enhancement; D011897:Random Allocation; D012008:Recurrence; D012501:Saphenous Vein / Q000637:transplantation*; D013382:Subtraction Technique; D013997:Time Factors