title: Endogenous digoxin-like immunoreactive substance in patients undergoing coronary surgery. Preliminary report.
abstract: Perioperative digoxin concentrations were measured in 20 unselected adult patients undergoing coronary surgery. None of the patients were receiving treatment with digoxin. A digoxin-like immunoreactive substance was found in 16 patients postoperatively. This substance, if pharmacologically active, may have important clinical implications in the management of patients after open heart surgery.
authors.affiliation: Department of Cardiac Surgery, Western Infirmary, Glasgow, Scotland.
authors.forename: S A
authors.initials: SA
authors.lastname: Nashef
authors.forename: A J
authors.initials: AJ
authors.lastname: Kirk
authors.forename: N
authors.initials: N
authors.lastname: Brewster
authors.forename: I
authors.initials: I
authors.lastname: Louden
authors.forename: I W
authors.initials: IW
authors.lastname: Percy-Robb
authors.forename: W H
authors.initials: WH
authors.lastname: Bain
mesh_terms: D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000378:metabolism*; D002298:Cardenolides; D001026:Coronary Artery Bypass; D004077:Digoxin; D005260:Female; D015200:Fluoroimmunoassay; D006801:Humans; D008297:Male; D008875:Middle Aged; D012503:Saponins
chemical_list: D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin