The cellular effects of estrogens on neuroendocrine tissues.
Estrogen action on sensitive neurons in the rat diencephalon has been studied by morphologic techniques; evidence of estrogen action at every level is presented, including tracts, cells, circuitry and subcellular organelles. The demonstration in the arcuate nucleus of estrogen-induced synaptic remodelling, estrogen-induced postsynaptic membrane phenotypes, changes in intracellular membranes and rapid estrogen actions on neuronal endo-exocytosis indicates that cellular estrogen actions may underlie the neuronal control of reproduction.
Naftolin
F
F
Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, CT 06510.
MacLusky
N J
NJ
Leranth
C Z
CZ
Sakamoto
H S
HS
Garcia-Segura
L M
LM
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000502:physiology*; D004967:Estrogens / Q000494:pharmacology*; D005260:Female; D008297:Male; D008954:Models, Biological; D009474:Neurons / Q000502:physiology; D009490:Neurosecretory Systems / Q000187:drug effects / Q000502:physiology*
D004967:Estrogens