Neuropeptide Y immunoreactivity in the locus coeruleus of the rat brain.
The detailed distribution of neuropeptide Y immunoreactive neurons and fibres is given for the rat locus coeruleus. The studies were carried out using indirect immunofluorescence and avidin-biotin-peroxidase techniques. It was shown that in colchicine pretreated rats, about 15-20% of locus coeruleus neurons contain neuropeptide Y immunoreactivity. Neuropeptide Y immunoreactive neurons form two populations: (1) medium-sized or large neurons, poorly immunostained, situated mainly in the dorsal and central locus coeruleus nucleus, and (2) small, strongly immunostained neurons in ventromedial parts of the nucleus. Neuropeptide Y immunoreactive fibres and terminals are scattered throughout the locus coeruleus, but are more numerous in its ventromedial and ventrorostral parts.
Smiałowska
M
M
Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland.
D000818:Animals; D001923:Brain Chemistry; D005455:Fluorescent Antibody Technique; D007124:Immunoenzyme Techniques; D008125:Locus Coeruleus / Q000032:analysis* / Q000166:cytology; D008297:Male; D009474:Neurons / Q000032:analysis; D009478:Neuropeptide Y / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D009478:Neuropeptide Y