Short-term and stabilized effects of percutaneous nephrolithotomy on the kidney.
A homogeneous group of 15 patients was investigated before and after percutaneous nephrolithotomy (PCN). Creatinine and electrolyte clearances evaluated both before and during saline (NaCl 0.9%) infusion, 4-7 days after PCN remained unchanged with respect to the preoperative values. A significant decrease of urinary PGE2 was observed postoperatively both before and after extracellular volume expansion. 99mTc-DTPA renography performed 26-40 days after surgery showed a scar on the convex margin of one kidney in the area of the nephrostomy and an improved renographic curve in 5 renal units. No difference between pre- and post-PCN isotopic clearances was evident. On the basis of our results we can affirm that PCN is an efficient and safe method for the treatment of nephrolithiasis.
Tasca
A
A
Istituto di Urologia, Università di Padova, Italia.
D'Angelo
A
A
Zattoni
F
F
Ferrarese
P
P
Calò
L
L
Bui
F
F
Cagnato
P
P
D000328:Adult; D015232:Dinoprostone; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D007669:Kidney Calculi / Q000503:physiopathology / Q000601:surgery*; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D011458:Prostaglandins E / Q000652:urine; D011866:Radioisotope Renography; D016284:Technetium Tc 99m Pentetate; D013997:Time Factors
D009942:Organometallic Compounds; D011458:Prostaglandins E; D004369:Pentetic Acid; D015232:Dinoprostone; D016284:Technetium Tc 99m Pentetate