title: Acetylation phenotypes in patients with bladder carcinoma.
abstract: The present study was done to evaluate the possible association of bladder carcinoma with the slow acetylator phenotype in a portuguese population. 49 patients with bladder carcinoma were compared to a normal control group of 84 individuals. No statistically significant association was detected. But when subdividing the group of slow acetylators it is found that in the subgroup with 12-36% acetylation there is a higher percentage of patients, which is statistically significant. These results are in agreement with two other studies, using populations of similar ethnic origin.
authors.affiliation: Instituto de Química Fisiológica, Faculdade de Medicina, Lisboa, Portugal.
authors.forename: M P
authors.initials: MP
authors.lastname: Bicho
authors.forename: L
authors.initials: L
authors.lastname: Breitenfeld
authors.forename: A A
authors.initials: AA
authors.lastname: Carvalho
authors.forename: C F
authors.initials: CF
authors.lastname: Manso
mesh_terms: D000107:Acetylation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011174:Portugal; D011379:Prognosis; D012016:Reference Values; D013030:Spain; D013418:Sulfamethazine; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000473:pathology
chemical_list: D013418:Sulfamethazine