title: Respiratory muscles in disease.
abstract: The respiratory muscles play an important role in the clinical manifestations of different disease states. Respiratory muscle dysfunction plays a primary role in the development of ventilatory failure in patients with neuromuscular disorders. Although the respiratory muscles are placed at a mechanical disadvantage in patients with obstructive lung disease, there is little clinical evidence to suggest that respiratory muscle dysfunction plays a primary role in the development of ventilatory failure.
authors.affiliation: Division of Pulmonary Medicine, University of Texas Health Science Center, Houston.
authors.forename: M J
authors.initials: MJ
authors.lastname: Tobin
mesh_terms: D001249:Asthma / Q000503:physiopathology*; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology*; D009119:Muscle Contraction; D009468:Neuromuscular Diseases / Q000503:physiopathology*; D011658:Pulmonary Fibrosis / Q000503:physiopathology*; D012119:Respiration; D012131:Respiratory Insufficiency / Q000503:physiopathology*; D012132:Respiratory Muscles / Q000503:physiopathology*; D013514:Surgical Procedures, Operative; D013909:Thorax / Q000002:abnormalities