title: [Induced variability in Acremonium chrysogenum, a producer of neutral-alkaline proteases and peptidases].
abstract: Lethal and mutagenic effects of N-nitrosomethyl biuret on the organism producing a complex of proteolytic enzymes i. e. Acremonium chrysogenum were studied. It was shown that methionine inhibited production of the protease complex in the induced prototrophic mutants. The selected mutants were classified according to the level of enzyme biosynthesis induction by methionine.
authors.forename: A G
authors.initials: AG
authors.lastname: Domracheva
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Bartoshevich
authors.forename: O D
authors.initials: OD
authors.lastname: Iudina
authors.forename: S A
authors.initials: SA
authors.lastname: Golubeva
authors.forename: O I
authors.initials: OI
authors.lastname: Bespalova
mesh_terms: D000164:Acremonium / Q000145:classification / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D004790:Enzyme Induction / Q000187:drug effects; D014644:Genetic Variation / Q000187:drug effects*; D008715:Methionine / Q000494:pharmacology; D009154:Mutation; D009602:Nitrosamines / Q000494:pharmacology; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D011480:Protease Inhibitors
chemical_list: D009602:Nitrosamines; D011480:Protease Inhibitors; C008654:N-nitroso-N-methylbiuret; D008715:Methionine; D010447:Peptide Hydrolases
vernacular_title: Indutsirovannaia izmenchivost' Acremonium chrysogenum produtsenta neĭtral'no-shchelochnykh proteaz i peptidaz.