Mitogenic stimulation of mouse lymphoid cells by Aleuria aurantia agglutinin.
An investigation was undertaken to determine if an agglutinin isolated from Aleuria aurantia possesses a mitogenic activity. Proliferation response of mouse lymphoid cell cultures was measured by 3H-thymidine uptake. The results revealed that Aleuria aurantia agglutinin at the concentration of 1 microgram/ml is mitogenic for Thy-1+ splenocytes and cortisone-resistant thymocytes.
Pajtasz
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Laboratory of Cellular Immunology, Polish Academy of Sciences, Wrocław.
Duś
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Debray
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D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D001487:Basidiomycota; D005260:Female; D006854:Hydrocortisone / Q000494:pharmacology; D007274:Injections, Intraperitoneal; D007376:Interleukin-2 / Q000096:biosynthesis; D037102:Lectins / Q000008:administration & dosage / Q000494:pharmacology*; D008213:Lymphocyte Activation; D051379:Mice; D008807:Mice, Inbred BALB C; D008934:Mitogens; D013154:Spleen / Q000166:cytology; D013601:T-Lymphocytes / Q000276:immunology*
D007376:Interleukin-2; D037102:Lectins; D008934:Mitogens; D006854:Hydrocortisone