Effect of short-term androgen administration to rabbit females on their lipoprotein metabolism.
The changes of lipoprotein profile were studied in rabbit females administered 1 mg/kg testosterone propionate i.m. daily for 7 days. Under such conditions a decrease of cholesterol in serum and in LDL fraction was found together with the increase of that in VLDL fraction. The level of triacylglycerols was decreased in serum, in VLDL and HDL fractions. These results showed that even a short-term administration or testosterone in pharmacological doses resulted not only in a decrease of total cholesterol in serum, but also influenced favourably its level in LDL fraction.
Hácik
T
T
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
Hromadová
M
M
D000818:Animals; D001055:Apolipoproteins B / Q000097:blood; D002784:Cholesterol / Q000097:blood; D005260:Female; D008074:Lipoproteins / Q000097:blood*; D011817:Rabbits; D012016:Reference Values; D013739:Testosterone / Q000494:pharmacology*; D014280:Triglycerides / Q000097:blood
D001055:Apolipoproteins B; D008074:Lipoproteins; D014280:Triglycerides; D013739:Testosterone; D002784:Cholesterol