title: [Conditions for immobilizing Streptomyces erythreus in a calcium alginate gel and the apparatus setup for the process].
abstract: A laboratory unit for production of calcium alginate gel granules with immobilized microorganisms is described. It provides sterile production of particles from tens micrometers to 2 mm in diameter. Expediency of using biocatalysts in the form of fine granules is exemplified with a number of immobilized microorganisms. Conditions for immobilizing the erythromycin producing organism by its incorporation into the calcium alginate gel were studied. Viability of the actinomycete in the gel was shown by consumption of the nutrients and biosynthesis of the antibiotic.
authors.forename: T E
authors.initials: TE
authors.lastname: Bryzgalova
authors.forename: V V
authors.initials: VV
authors.lastname: Tsibanov
authors.forename: A D
authors.initials: AD
authors.lastname: Nekliudov
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Bartoshevich
mesh_terms: D000464:Alginates / Q000494:pharmacology*; D001431:Bacteriological Techniques / Q000295:instrumentation; D002384:Catalysis; D003470:Culture Media / Q000378:metabolism; D004917:Erythromycin / Q000096:biosynthesis; D004926:Escherichia coli / Q000254:growth & development; D005782:Gels; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D010316:Particle Size; D011548:Pseudomonadaceae / Q000254:growth & development; D013302:Streptomyces / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism
chemical_list: D000464:Alginates; D003470:Culture Media; D005782:Gels; D006603:Hexuronic Acids; D004917:Erythromycin; D020723:Glucuronic Acid
vernacular_title: Izuchenie usloviĭ immobilizatsii Streptomyces erythreus v kal'tsiĭ-al'ginatnom gele i apparaturnoe oformlenie protsessa.