title: Congenital cardiac tumors in association with orofacial clefts.
abstract: The case of an infant with a complete cleft of the primary and secondary palate (class III) and right unilateral complete cleft lip who demonstrated failure to thrive due to a primary congenital cardiac fibroma is described. This tumor required cardiac transplantation for effective treatment. A review of the literature, although replete with associations of cleft lip/palate and congenital heart disease, does not reveal a congenital cardiac tumor/orofacial cleft association or syndrome. Failure to thrive, however, which is common in such infants, may well be associated with congenital cardiac anomalies and should be carefully ruled out. Treatment of cardiac fibromas is discussed along with the usefulness of two-dimensional echocardiography and the importance of the team approach in the management of these infants.
authors.affiliation: Department of General Surgery, Cooper Hospital/University Medical Center, Camden, NJ.
authors.forename: L M
authors.initials: LM
authors.lastname: Back
authors.forename: A S
authors.initials: AS
authors.lastname: Brown
authors.forename: L R
authors.initials: LR
authors.lastname: Barot
mesh_terms: D002971:Cleft Lip / Q000150:complications*; D002972:Cleft Palate / Q000150:complications*; D004452:Echocardiography; D005183:Failure to Thrive / Q000209:etiology; D005260:Female; D005350:Fibroma / Q000151:congenital* / Q000628:therapy; D006338:Heart Neoplasms / Q000151:congenital* / Q000628:therapy; D016027:Heart Transplantation; D006352:Heart Ventricles; D006801:Humans; D007231:Infant, Newborn