title: IgE-dependent killing of Schistosoma mansoni schistosomula by human platelets: modulation by T cell products.
abstract: The in vitro stimulation of T lymphocytes is known to induce the release of factors that possess distinct biological activities. In the present report, we describe the presence, in supernatants of Schistosoma mansoni antigen stimulated T cells from S. mansoni infected patients, of a factor able to inhibit the IgE-dependent platelet cytotoxicity of the same individuals toward the young larvae of S. mansoni.
authors.affiliation: Centre d'Immunologie et de Biologie Parasitaire, Institut Pasteur, Lille, France.
authors.forename: V
authors.initials: V
authors.lastname: Pancré
authors.forename: J Y
authors.initials: JY
authors.lastname: Cesbron
authors.forename: M
authors.initials: M
authors.lastname: Joseph
authors.forename: M
authors.initials: M
authors.lastname: Barbier
authors.forename: A
authors.initials: A
authors.lastname: Capron
authors.forename: C
authors.initials: C
authors.lastname: Auriault
mesh_terms: D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D001792:Blood Platelets / Q000276:immunology*; D002474:Cell-Free System; D005434:Flow Cytometry; D006801:Humans; D007073:Immunoglobulin E / Q000502:physiology*; D007814:Larva / Q000276:immunology; D008213:Lymphocyte Activation; D012550:Schistosoma mansoni / Q000254:growth & development / Q000276:immunology*; D013491:Suppressor Factors, Immunologic / Q000502:physiology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D013491:Suppressor Factors, Immunologic; D007073:Immunoglobulin E