title: Acute pulmonary embolism: diagnostic value of digital subtraction angiography.
abstract: Digital subtraction angiography (DSA) performed via a peripheral vein was compared prospectively with selective conventional pulmonary angiography (CPA) in 54 patients suspected of having pulmonary embolism (PE). All patients also underwent ascending venography. In contrast to the conventional pulmonary angiograms, all of which were considered satisfactory, 13 of 54 digital subtraction angiograms (24%) were technically unsatisfactory. The interpretable digital subtraction angiograms had 81% sensitivity and 64% specificity. With DSA, one cannot exclude the diagnosis of PE on the basis of normal angiograms (27% false-positive results) as one can with perfusion scanning. On the other hand, DSA showed good sensitivity (94%) in medium to major PE. Therefore it may be the technique of choice in the screening of life-threatening PE for which curative emergency treatment with thrombolytic agents or embolectomy is often necessary.
authors.affiliation: Department of Radiology, Hôpital Antoine Beclere, Clamart, France.
authors.forename: D
authors.initials: D
authors.lastname: Musset
authors.forename: J
authors.initials: J
authors.lastname: Rosso
authors.forename: P
authors.initials: P
authors.lastname: Petitpretz
authors.forename: P
authors.initials: P
authors.lastname: Girard
authors.forename: M P
authors.initials: MP
authors.lastname: Hauuy
authors.forename: G
authors.initials: G
authors.lastname: Simonneau
authors.forename: M
authors.initials: M
authors.lastname: Labrune
authors.forename: P
authors.initials: P
authors.lastname: Duroux
mesh_terms: D000208:Acute Disease; D000792:Angiography / Q000379:methods*; D005189:False Positive Reactions; D006801:Humans; D008875:Middle Aged; D010690:Phlebography; D011446:Prospective Studies; D011651:Pulmonary Artery / Q000000981:diagnostic imaging*; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging*; D011856:Radiographic Image Enhancement; D013382:Subtraction Technique