[Conditions for immobilizing Streptomyces erythreus in a calcium alginate gel and the apparatus setup for the process].
A laboratory unit for production of calcium alginate gel granules with immobilized microorganisms is described. It provides sterile production of particles from tens micrometers to 2 mm in diameter. Expediency of using biocatalysts in the form of fine granules is exemplified with a number of immobilized microorganisms. Conditions for immobilizing the erythromycin producing organism by its incorporation into the calcium alginate gel were studied. Viability of the actinomycete in the gel was shown by consumption of the nutrients and biosynthesis of the antibiotic.
Bryzgalova
T E
TE
Tsibanov
V V
VV
Nekliudov
A D
AD
Bartoshevich
Iu E
IuE
D000464:Alginates / Q000494:pharmacology*; D001431:Bacteriological Techniques / Q000295:instrumentation; D002384:Catalysis; D003470:Culture Media / Q000378:metabolism; D004917:Erythromycin / Q000096:biosynthesis; D004926:Escherichia coli / Q000254:growth & development; D005782:Gels; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D010316:Particle Size; D011548:Pseudomonadaceae / Q000254:growth & development; D013302:Streptomyces / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism
D000464:Alginates; D003470:Culture Media; D005782:Gels; D006603:Hexuronic Acids; D004917:Erythromycin; D020723:Glucuronic Acid
Izuchenie usloviĭ immobilizatsii Streptomyces erythreus v kal'tsiĭ-al'ginatnom gele i apparaturnoe oformlenie protsessa.