Pneumocystis carinii pneumonia following heart transplantation.
Pneumocystis carinii pneumonia represents a rare complication that is associated with a high mortality following heart transplantation. The cases of two heart transplant recipients who developed Pneumocystis pneumonia within the first 3 postoperative months are reported. Both patients had severe clinical symptoms of the disease; the diagnosis was confirmed by bronchoalveolar lavage, and the patients were treated with a combination of trimethoprim and sulfamethoxazole. Both patients recovered and are well at the time of this report.
Schäfers
H J
HJ
Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Federal Republic of Germany.
Cremer
J
J
Wahlers
T
T
Holle
W
W
Fieguth
H G
HG
Herrmann
G
G
Haverich
A
A
D000328:Adult; D003524:Cyclosporins / Q000627:therapeutic use; D004338:Drug Combinations / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D016027:Heart Transplantation; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy / Q000209:etiology* / Q000401:mortality; D011183:Postoperative Complications / Q000209:etiology*; D013419:Sulfamethizole / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use; D000096926:Benzenesulfonamides
D003524:Cyclosporins; D004338:Drug Combinations; D013419:Sulfamethizole; D014295:Trimethoprim; C029078:trimethoprim sulfamethizole; D000096926:Benzenesulfonamides