title: Enoxacin in the treatment of sexually transmitted diseases.
abstract: Enoxacin was evaluated in two double-blind comparative trials in a total of 200 male and female patients with urethral and/or endocervical gonorrhoea. Single 400-mg doses were effective in eradicating Neisseria gonorrhoeae (including penicillinase-producing strains) from patients. Enoxacin was as effective as the parenteral drugs approved for treatment. Adverse events occurred in 3% of patients. Enoxacin has been shown to be an effective well tolerated and convenient treatment for gonorrhoea.
authors.affiliation: Institut Alfred Fournier, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Siboulet
authors.forename: J M
authors.initials: JM
authors.lastname: Bohbot
authors.forename: F
authors.initials: F
authors.lastname: Catalan
mesh_terms: D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D015365:Enoxacin; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009287:Naphthyridines / Q000008:administration & dosage / Q000627:therapeutic use*; D011897:Random Allocation; D012749:Sexually Transmitted Diseases / Q000188:drug therapy*; D014526:Urethritis / Q000188:drug therapy; D002575:Uterine Cervicitis / Q000188:drug therapy
chemical_list: D000890:Anti-Infective Agents; D009287:Naphthyridines; D015365:Enoxacin