PTFE versus human umbilical vein in above knee femoro-popliteal bypass. Early results of a randomized clinical trial.
The results of a prospective randomized clinical trial comparing PTFE and HUV grafts in above knee femoro-popliteal reconstruction are presented. A total of 93 limbs were randomized, three patients died in the early postoperative period, leaving 90 (45 PTFE and 45 HUV bypasses) to be analysed. During 18 months of follow-up only 3 HUV grafts occluded in contrast to 15 occluded PTFE grafts. After one year patency rates for HUV were 90% versus 67% for PTFE grafts, after 18 months 86% and 63% respectively. From one year postoperatively onwards these results are statistically and significantly different. When an above knee femoro-popliteal reconstruction is performed and autologous vein is not available or purposely not used, HUV gives better results than PTFE and is the graft of choice.
Aalders
G J
GJ
Department of Surgery, St. Elisabeth Hospital, Tilburg, The Netherlands.
van Vroonhoven
T J
TJ
Lobach
H J
HJ
Wijffels
C C
CC
D000714:Anastomosis, Surgical; D001807:Blood Vessel Prosthesis; D002986:Clinical Trials as Topic; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D007717:Knee; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011150:Popliteal Artery / Q000601:surgery*; D011446:Prospective Studies; D011897:Random Allocation; D014471:Umbilical Veins / Q000637:transplantation*; D014654:Vascular Patency
D011138:Polytetrafluoroethylene