title: Sequential dose injections. A new technique for technetium-99m colloid gastrointestinal bleeding studies.
abstract: For Tc-99m colloid bleeding studies to be positive, the patient must be actively bleeding while the colloid is circulating in the blood pool. A simple technique of sequential dose injections (SDI) is presented where five injections of 2 mCi each are made at 5-minute intervals. Image acquisition is performed after each injection. This technique results in an increase in the effective plasma residence time of the colloidal particles from 10-15 minutes to 35-40 minutes. A case report is presented in which the bleeding site was identified only after the fifth serial injection of a fractionated dose of Tc-99m microaggregated albumin colloid.
authors.affiliation: Department of Nuclear Medicine, Kuakini Medical Center, Honolulu, Hawaii.
authors.forename: C B
authors.initials: CB
authors.lastname: Delaplain
authors.forename: M C
authors.initials: MC
authors.lastname: Ling
authors.forename: F
authors.initials: F
authors.lastname: Yeh
authors.forename: R D
authors.initials: RD
authors.lastname: Wasnich
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004334:Drug Administration Schedule; D006471:Gastrointestinal Hemorrhage / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin / Q000008:administration & dosage
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin