In vitro synthesis of immunoglobulins in cutaneous leishmaniasis.
In an in vitro study, IgG was synthesized in large amounts by tissue from cutaneous leishmaniasis lesions. IgA and IgM were produced in the minority of the cultures in distinct and small amounts, respectively. Synthesis of complement (C3 and C4) could not be detected, but lysozyme was produced sporadically. The significance of these findings is discussed.
Lai A Fat
Department of Dermatology, University Hospital, Paramaribo, Suriname.
Pin Jin
J C
JC
Lieuw A Joe
R G
RG
Diesselhoff-den Dulk
M M
MM
van Furth
R
R
D000818:Animals; D001345:Autoradiography; D001706:Biopsy; D046508:Culture Techniques; D006801:Humans; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D007136:Immunoglobulins / Q000096:biosynthesis*; D007896:Leishmaniasis / Q000276:immunology*; D012867:Skin / Q000473:pathology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins