Proteinuria and statural growth.
In order to assess the possible effects of proteinuria on statural growth, we studied 14 children with various glomerulopathies and proteinuria persistently above 30 mg/kg/day which were followed-up for 1.5-4.3 years. They had received only short-term steroid therapy or no steroids at all. During the follow-up, 3 patients lost 1-2.1 height standard deviation scores. These patients had proteinuria above 100 mg/kg/day with associated glycosuria, and they went into chronic renal failure. The other patients had minor variations of the growth curve. In our experience heavy proteinuria represents a risk factor for growth delay when it is associated with glycosuria and chronic renal failure.
Polito
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C
Department of Paediatrics, 1st Faculty of Medicine and Surgery, University of Naples, Italy.
La Manna
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A
Olivieri
A N
AN
Di Toro
R
R
D001827:Body Height; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005921:Glomerulonephritis / Q000150:complications; D006130:Growth Disorders / Q000209:etiology*; D006801:Humans; D008297:Male; D011507:Proteinuria / Q000150:complications*; D013997:Time Factors