Multifocal eosinophilic granuloma.
A 22-year-old black male presented with progressive dyspnea, a nonproductive cough, and new skin lesions. He was severely hypoxic, and had a severe restrictive defect on pulmonary function testing. A 2-cm lytic defect was noted on skull radiographs. A lung biopsy demonstrated pulmonary fibrosis. A biopsy of a skin lesion was consistent with a diagnosis of multifocal eosinophilic granuloma, or disseminated histiocytosis X. The case presents several unusual features of this uncommon disorder.
Morley
T F
TF
Department of Internal Medicine, University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine, Stratford.
Silverstein
S D
SD
Giudice
J C
JC
Csere
R S
RS
D000328:Adult; D004803:Eosinophilic Granuloma / Q000175:diagnosis; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D008297:Male; D011658:Pulmonary Fibrosis / Q000175:diagnosis