title: Two further cases of acute myeloid leukemia with trisomy 4.
abstract: Two cases of acute myeloid leukemia (FAB M1 and M2) with trisomy 4 are described. Morphologic abnormalities were confined to the granulocytic monocytic lineage with no evidence of erythroid or megakaryocytic involvement. One of the cases, who also had trisomy 13, presented initially with skin infiltration without bone marrow involvement.
authors.affiliation: Department of Haematological Medicine, University Clinical School, Cambridge, England.
authors.forename: C F
authors.initials: CF
authors.lastname: Hoyle
authors.forename: B J
authors.initials: BJ
authors.lastname: Boughton
authors.forename: F G
authors.initials: FG
authors.lastname: Hayhoe
mesh_terms: D000368:Aged; D002478:Cells, Cultured; D002871:Chromosome Banding; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008875:Middle Aged; D010996:Pleural Effusion / Q000473:pathology; D014314:Trisomy