title: Serotonin antagonism in the treatment of systemic hypertension: the role of ketanserin.
abstract: Serotonin has various hemodynamic effects, and may play a role in systemic hypertension. Ketanserin is a specific S2 serotonergic receptor blocker with possible adrenergic blocking activities that has clinical utility in the treatment of hypertension. The drug may have particular advantages for various patient populations.
authors.affiliation: Albert Einstein College of Medicine, Bronx, New York.
authors.forename: W H
authors.initials: WH
authors.lastname: Frishman
authors.forename: S
authors.initials: S
authors.lastname: Okin
authors.forename: S
authors.initials: S
authors.lastname: Huberfeld
mesh_terms: D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D007650:Ketanserin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D010975:Platelet Aggregation Inhibitors
chemical_list: D010975:Platelet Aggregation Inhibitors; D007650:Ketanserin