title: Synthesis and biological activity of some pyrrole derivatives. I.
abstract: The synthesis of some 5-substituted 2-amino-3-cyano (and 3-carboethoxy)pyrroles is described starting from the cyano- and carboethoxyacetomidines and the alpha-halogeno ketones. The compounds tested in vitro as antimicrobial agents did not show any significative activity.
authors.affiliation: Istituto di Chimica Farmaceutica, Tossicologica ed Applicata Università di Cagliari, Italy.
authors.forename: M T
authors.initials: MT
authors.lastname: Cocco
authors.forename: C
authors.initials: C
authors.lastname: Congiu
authors.forename: A
authors.initials: A
authors.lastname: Maccioni
authors.forename: A
authors.initials: A
authors.lastname: Plumitallo
authors.forename: M L
authors.initials: ML
authors.lastname: Schivo
authors.forename: G
authors.initials: G
authors.lastname: Palmieri
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D002176:Candida albicans / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011758:Pyrroles