Prognostic factors in the hemolytic-uremic syndrome.
During 1972-1986, 142 children with the hemolytic-uremic syndrome were treated. Most of them were infants (73%). The total mortality rate reached 25.4%. Computer analysis revealed the following risk factors of a fatal outcome: severe gastrointestinal symptoms during the prodromal period, coma, convulsions, malignant hypertension, persistence of prodromal symptoms over 7 days, hyperkalemia over 7 mmol/l, acidosis with bicarbonate level less than 15 mmol/l, a delay of over 5 days in starting dialysis, and transport to dialysis unit of over 100 km. The greatest risk of death existed during the first 3 weeks from onset. Among 142 children, 106 survived the acute phase. They were followed up from 2 to 16 years. Nine were lost to follow-up. Twelve children developed chronic renal failure.
Uszycka-Karcz
M
M
Pediatric Clinic of Nephrology, Gdańsk, Poland.
Marczak
E
E
Mierzewski
P
P
Zurowska
A
A
Schramm
K
K
Gockowska
Z
Z
D016002:Discriminant Analysis; D005260:Female; D005500:Follow-Up Studies; D006463:Hemolytic-Uremic Syndrome / Q000401:mortality*; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000453:epidemiology; D015993:Life Tables; D008297:Male; D011379:Prognosis; D012307:Risk Factors; D013997:Time Factors