title: Effect of recent antibacterial agents against bacteria causing diarrhoea.
abstract: The susceptibility of 424 bacterial isolates causing diarrhoea were tested by agar dilution technique on Mueller-Hinton Agar against amoxicillin, ampicillin, ceftriaxone, chloramphenicol, co-trimoxazole, ciprofloxacin, doxycycline, norfloxacin and ofloxacin. The bacterial species included were Aeromonas hydrophila, Edwardsiella tarda, Pleisomonas shigelloides, Salmonella spp., Shigella spp., Vibrio cholerae and Vibrio parahaemolyticus. The most active compounds were the fluorinated 4-quinolones studied, that is, ciprofloxacin, norfloxacin and ofloxacin, and ceftriaxone. The other antibacterial agents were considerably less active; a substantial portion of tested isolates were resistant to them.
authors.affiliation: Department of Microbiology, Faculty of Medicine, National University of Singapore.
authors.forename: T
authors.initials: T
authors.lastname: Bergan
authors.forename: S
authors.initials: S
authors.lastname: Lolekha
authors.forename: M K
authors.initials: MK
authors.lastname: Cheong
authors.forename: C L
authors.initials: CL
authors.lastname: Poh
authors.forename: S
authors.initials: S
authors.lastname: Doencham
authors.forename: D
authors.initials: D
authors.lastname: Charoenpipop
mesh_terms: D042462:4-Quinolones; D000667:Ampicillin / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002443:Ceftriaxone / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003967:Diarrhea / Q000382:microbiology*; D004318:Doxycycline / Q000494:pharmacology; D004338:Drug Combinations / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D013420:Sulfamethoxazole / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D004338:Drug Combinations; D002701:Chloramphenicol; D002443:Ceftriaxone; D000667:Ampicillin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole; D004318:Doxycycline