Kasabach-Merritt syndrome.
Eight infants with hemangiomata associated with severe consumption coagulopathy are reviewed; three died. The presentations and method of management are discussed. The varied response to different modalities of therapy initiated this report and led to a search of the world literature in an attempt to identify the pattern of response, if any, to particular therapy. From our own experience with two cases and from the review of the literature, it appears that radiotherapy alone or in combination with steroids gives a superior overall treatment in terms of reducing the death rate.
el-Dessouky
M
M
Department of Paediatric Surgery, Royal Hospital for Sick Children, Yorkhill, Glasgow, Scotland.
Azmy
A F
AF
Raine
P A
PA
Young
D G
DG
D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000628:therapy*; D005260:Female; D006258:Head and Neck Neoplasms / Q000628:therapy; D006391:Hemangioma / Q000628:therapy*; D006801:Humans; D007223:Infant; D007866:Leg; D008113:Liver Neoplasms / Q000628:therapy; D008297:Male; D013577:Syndrome