Macroautophagic phenomena in renin granules.
The secretory granules of murine epithelioid cells take up and probably degrade mitochondria; they thus appear to have macroautophagic properties. As renin granules also have other properties uncommon for secretory granules, they are suggested to fulfill functions in these cells otherwise reserved for lysosomes.
Taugner
R
R
Department of Physiology I, University of Heidelberg, Federal Republic of Germany.
Metz
R
R
Rosivall
L
L
D000315:Adrenalectomy; D000818:Animals; D003594:Cytoplasmic Granules / Q000201:enzymology* / Q000648:ultrastructure; D007672:Kidney Cortex / Q000166:cytology / Q000201:enzymology* / Q000648:ultrastructure; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008854:Microscopy, Electron; D012016:Reference Values; D012083:Renin / Q000378:metabolism*
D012083:Renin