[Effect of ovalbumin lysozyme on healing of standard skin wounds in guinea pigs].
External application of ovalbumin Lysozyme in normal saline in enzyme concentration 1 mg/ml shortened evidently the time of healing of standard skin wounds in guinea pigs (p less than 0.00001) as compared to control groups. The inflammatory reaction around the wound was reduced also. No manifestations of allergy to ovalbumin lysozyme were noted. This favourable effect of lysozyme on wound healing seems to be related to the cationic influence of lysozyme on cell membranes of keratinocytes and on change of wound pH.
Gasior-Chrzan
B
B
D000279:Administration, Cutaneous; D000818:Animals; D004353:Drug Evaluation, Preclinical; D005260:Female; D006168:Guinea Pigs; D008297:Male; D009113:Muramidase / Q000008:administration & dosage / Q000627:therapeutic use*; D010047:Ovalbumin / Q000008:administration & dosage / Q000627:therapeutic use*; D011044:Poland; D012867:Skin / Q000187:drug effects* / Q000293:injuries; D014945:Wound Healing / Q000187:drug effects*; D014947:Wounds and Injuries / Q000188:drug therapy*
D010047:Ovalbumin; D009113:Muramidase
Wpływ lizozymu białka jaja kurzego na gojenie standaryzowanych ran skóry świnek morskich.