Histidyl-proline diketopiperazine causes satiety by antagonism of norepinephrine metabolism in the hypothalamic paraventricular nucleus.
Wilber
J
J
Department of Medicine, Louisiana State University Medical Center, New Orleans 70112-2822.
Prasad
C
C
Yamada
M
M
Spahn
S
S
Rogers
D
D
D000818:Animals; D005215:Fasting; D005502:Food; D008734:Methoxyhydroxyphenylglycol / Q000378:metabolism; D009638:Norepinephrine / Q000037:antagonists & inhibitors* / Q000378:metabolism; D010286:Paraventricular Hypothalamic Nucleus / Q000187:drug effects / Q000378:metabolism*; D010456:Peptides, Cyclic / Q000378:metabolism / Q000494:pharmacology*; D010879:Piperazines / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012527:Satiation / Q000187:drug effects*
D010456:Peptides, Cyclic; D010879:Piperazines; D008734:Methoxyhydroxyphenylglycol; C015924:histidyl-proline diketopiperazine; D009638:Norepinephrine