title: [Treatment of Sjögren's syndrome with protease inhibitors].
abstract: The authors reported the results of therapy of 28 patients with primary and secondary Sjogren's syndrome by iv injections of protease inhibitors (contrykal and trasylol). Findings of clinical and laboratory tests showed a significant increase in salivation and lacrimation. The elimination of concomitant oral candidosis raised the efficacy of treatment of xerostomia in many patients.
authors.forename: G P
authors.initials: GP
authors.lastname: Matveĭkov
authors.forename: N F
authors.initials: NF
authors.lastname: Soroka
authors.forename: L I
authors.initials: LI
authors.lastname: Paliĭ
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D011480:Protease Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D012472:Salivation / Q000187:drug effects; D012859:Sjogren's Syndrome / Q000188:drug therapy*; D013666:Tears / Q000187:drug effects / Q000378:metabolism; D014985:Xerophthalmia / Q000188:drug therapy; D014987:Xerostomia / Q000188:drug therapy
chemical_list: D011480:Protease Inhibitors
vernacular_title: Lechenie sindroma Shegrena ingibitorami proteaz.