[Induced variability in Acremonium chrysogenum, a producer of neutral-alkaline proteases and peptidases].
Lethal and mutagenic effects of N-nitrosomethyl biuret on the organism producing a complex of proteolytic enzymes i. e. Acremonium chrysogenum were studied. It was shown that methionine inhibited production of the protease complex in the induced prototrophic mutants. The selected mutants were classified according to the level of enzyme biosynthesis induction by methionine.
Domracheva
A G
AG
Bartoshevich
Iu E
IuE
Iudina
O D
OD
Golubeva
S A
SA
Bespalova
O I
OI
D000164:Acremonium / Q000145:classification / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D004790:Enzyme Induction / Q000187:drug effects; D014644:Genetic Variation / Q000187:drug effects*; D008715:Methionine / Q000494:pharmacology; D009154:Mutation; D009602:Nitrosamines / Q000494:pharmacology; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D011480:Protease Inhibitors
D009602:Nitrosamines; D011480:Protease Inhibitors; C008654:N-nitroso-N-methylbiuret; D008715:Methionine; D010447:Peptide Hydrolases
Indutsirovannaia izmenchivost' Acremonium chrysogenum produtsenta neĭtral'no-shchelochnykh proteaz i peptidaz.