title: Primary immunodeficiency diseases: a presentation of 6 cases.
abstract: The peripheral blood leukocytes of 6 children with clinical data suggestive of primary cellular immunodeficiencies were studied in an attempt to define the cellular basis of these disorders. The phenotype and function of T and B cells were investigated. According to the clinical and laboratory features, the patients were classified as one case of severe combined immunodeficiency (SCID), two of ataxia-telangiectasia (AT), one of Wiskott-Aldrich syndrome (WAS), one of DiGeorge syndrome (DSG), and one of cellular immunodeficiency (CID). The laboratory investigations together with the clinical manifestations permitted a diagnosis of primary immunodeficiency diseases.
authors.affiliation: Seção de Immunologia, Instituto Adolfo Lutz, Sâo Paulo, Brasil.
authors.forename: A C
authors.initials: AC
authors.lastname: de Araujo
authors.forename: E
authors.initials: E
authors.lastname: de los Santos-Fortuna
authors.forename: M M
authors.initials: MM
authors.lastname: Carneiro-Sampaio
authors.forename: A S
authors.initials: AS
authors.lastname: Grumach
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000276:immunology*; D007223:Infant; D008214:Lymphocytes / Q000145:classification; D008297:Male; D013601:T-Lymphocytes / Q000276:immunology*