Cholestatic disorders of infancy.
We no longer view the infant with persistent cholestasis with a "wait and see" strategy. Identification of the cause of "neonatal hepatitis" may allow specific treatment. Improved surgical techniques for portoenterostomy have provided early hope for patients with biliary atresia. Rapidly advancing nutritional strategies allow many portoenterostomy failures an additional further option, that is, hepatic transplantation. I express my thanks to the many investigators who have contributed and are continuing to advance the progress recounted in this review. Perusal of the references cited in this review makes clear the identity of these investigators.
Fitzgerald
J F
JF
Indiana University School of Medicine, Indianapolis, Indiana.
D002779:Cholestasis / Q000150:complications / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D003550:Cystic Fibrosis / Q000150:complications; D006801:Humans; D007018:Hypopituitarism / Q000150:complications; D007223:Infant; D007231:Infant, Newborn; D019896:alpha 1-Antitrypsin Deficiency