title: Haemostatic aspects of renal transplantation.
abstract: Platelet function and protein C activity and antigen level was studied in 31 renal transplant recipients and 10 healthy controls. The patients were divided into three groups: (I) cyclosporin treated, (II) azathioprine treated, and (III) azathioprine treated patients with chronic rejection. The platelet function in the renal transplant patients was normal and there was no difference between groups I and II. The specific activity of protein C was decreased in patients after renal transplantation and decreasing protein C activity and progressive renal failure was found to be positively correlated in the azathioprine treated groups.
authors.affiliation: Department of Nephrology, Aalborg Hospital, Denmark.
authors.forename: P J
authors.initials: PJ
authors.lastname: Sørensen
authors.forename: E B
authors.initials: EB
authors.lastname: Schmidt
authors.forename: F
authors.initials: F
authors.lastname: Knudsen
authors.forename: A H
authors.initials: AH
authors.lastname: Nielsen
authors.forename: S D
authors.initials: SD
authors.lastname: Kristensen
authors.forename: J
authors.initials: J
authors.lastname: Dyerberg
authors.forename: H J
authors.initials: HJ
authors.lastname: Kornerup
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects*; D003404:Creatinine / Q000378:metabolism; D003524:Cyclosporins / Q000494:pharmacology*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011486:Protein C / Q000378:metabolism*
chemical_list: D003524:Cyclosporins; D011486:Protein C; D003404:Creatinine; D001379:Azathioprine