title: C-anaphases in lymphocyte cultures versus premature centromere division syndromes.
abstract: Different cases in which chromosomes obtained from short-term lymphocyte cultures appear with separated centromeres are reviewed. These include: (1) C-anaphases in the colchicine-resistance mutation, (2) C-anaphases as a common variant, (3) premature centromere division (PCD) in elderly women, (4) PCD in Alzheimer's disease, (5) early splitting and puffing of centromeres in Roberts' syndrome.
authors.affiliation: Laboratoire de Cytogénétique, Maternité, Hôpital Pellegrin, Bordeaux, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Chamla
mesh_terms: D000705:Anaphase; D002503:Centromere; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002875:Chromosomes; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000166:cytology* / Q000648:ultrastructure