Absence of any male-specific antigen recognized by T lymphocytes in X/XSxr' male mice.
Previous work has established that whereas X/X mice carrying the sex-reversing chromosomal fragment Sxr are positive for the male-specific transplantation antigen, H-Y, X/X mice carrying the variant Sxr', although they too develop as phenotypic males, are H-Y negative. In this paper we show that X/XSxr' male mice do not express any male-specific antigen that can induce skin-graft rejection.
McLaren
A
A
MRC Mammalian Development Unit, London, U.K.
Hunt
R
R
Simpson
E
E
D000818:Animals; D012734:Disorders of Sex Development; D005260:Female; D006084:Graft Rejection; D006182:H-Y Antigen / Q000032:analysis*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008817:Mice, Mutant Strains; D012737:Sex Factors; D016038:Skin Transplantation; D013601:T-Lymphocytes / Q000276:immunology*
D006182:H-Y Antigen