title: Aging-related skin changes: development and clinical meaning.
abstract: The medical literature is replete with articles that discuss the spectrum of sun-induced changes in human skin. These extrinsic, actinically induced changes, more prevalent in the elderly, include wrinkling and loss of elasticity; dyspigmentation; vascular ectasias and hemorrhage; atrophy; and benign and malignant neoplasms. This article, however, focuses on the intrinsic changes behind geriatric skin problems, providing a non-specialist's illustrated guide to recognizing structural and functional changes due to normal, chronological aging and how they manifest clinically in elderly patients.
authors.affiliation: Department of Internal Medicine, University of South Florida College of Medicine, Tampa.
authors.forename: M L
authors.initials: ML
authors.lastname: Richey
authors.forename: H K
authors.initials: HK
authors.lastname: Richey
authors.forename: N A
authors.initials: NA
authors.lastname: Fenske
mesh_terms: D000375:Aging / Q000378:metabolism / Q000473:pathology* / Q000502:physiology; D001833:Body Temperature Regulation; D003094:Collagen / Q000378:metabolism; D006201:Hair Diseases / Q000209:etiology; D006801:Humans; D007801:Langerhans Cells / Q000276:immunology; D008544:Melanocytes / Q000378:metabolism; D009260:Nail Diseases / Q000209:etiology; D012867:Skin / Q000378:metabolism / Q000473:pathology*; D012871:Skin Diseases / Q000209:etiology*; D012878:Skin Neoplasms / Q000209:etiology; D012879:Skin Physiological Phenomena
chemical_list: D003094:Collagen