Comparative studies of the haemagglutination of adult and umbilical cord erythrocytes by animal lectins.
1. The sugar specificities of four lactose-binding lectins were studied through the agglutination of adult and/or umbilical cord human erythrocytes (AHRBC and/or CHRBC). 2. Rana catesbeiana egg lectin specifically agglutinated both intact blood group A-AHRBC and intact blood group A-CHRBC. 3. Rana catesbeiana liver lectin agglutinated intact A-AHRBC much more strongly than intact A-CHRBC. 4. Xenopus laevis skin lectin nonspecifically agglutinated AHRBC and CHRBC. 5. Plecoglossus altivelis egg lectin specifically agglutinated intact B-AHRBC, but weakly agglutinated intact B-CHRBC. 6. Comparative studies of lectin-induced AHRBC or CHRBC agglutination clarified the sugar-binding specificities of these lectins.
Nitta
K
K
Cancer Research Institute, Tohoku College of Pharmaceutical Sciences, Sendai, Japan.
Terasaki
Y
Y
Kawauchi
H
H
Takayanagi
G
G
D000328:Adult; D000818:Animals; D004912:Erythrocytes / Q000276:immunology; D005312:Fetal Blood / Q000276:immunology; D005399:Fishes; D037541:Galectin 4; D006384:Hemagglutination; D006388:Hemagglutinins / Q000302:isolation & purification; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D037102:Lectins / Q000302:isolation & purification / Q000494:pharmacology*; D011892:Rana catesbeiana; D014982:Xenopus laevis
D037541:Galectin 4; D006388:Hemagglutinins; D037102:Lectins