title: Promoting effects of 105K glycoprotein on cell proliferation in chicken lymphoblastoid cell lines.
abstract: The promoting effects on cell proliferation of the 105K glycoprotein (105Kgp), purified from sera of chickens to which a Marek's disease (MD) lymphoblastoid cell line, MDCC-MSB1-41C (MSB1-41C), had been transplanted, were examined using culture cells from various sources. The MSB1-41C line as well as the other chicken lymphoblastoid cell lines examined were sensitive to the 105Kgp. The growth-promoting effects of 105Kgp showed a biphasic pattern depending upon the amount of 105Kgp added into the culture medium. These findings indicate that the 105Kgp may be a promoting factor for chicken growing cells, especially lymphoblastoid cell lines.
authors.affiliation: Department of Microbiology and Hygiene, Faculty of Applied Biological Science, Hiroshima University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Kotomura
authors.forename: H
authors.initials: H
authors.lastname: Matsuda
authors.forename: M
authors.initials: M
authors.lastname: Murata
authors.forename: K
authors.initials: K
authors.lastname: Matsumura
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002645:Chickens; D006023:Glycoproteins / Q000097:blood / Q000494:pharmacology*; D006133:Growth Substances / Q000097:blood / Q000494:pharmacology; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects*; D008380:Marek Disease / Q000097:blood; D008970:Molecular Weight
chemical_list: D006023:Glycoproteins; D006133:Growth Substances