Analysing changes in the presence of informative right censoring caused by death and withdrawal.
Several approaches for estimating and comparing the rates of change of a continuous variable in two treatment groups in the presence of informative right censoring are reviewed and compared. The comparisons are made under different models for the censoring probabilities and various types of treatment effects. Some recommendations are discussed regarding the application of these approaches to the different settings.
Wu
M C
MC
Biostatistics Research Branch, National Heart, Lung, and Blood Institute, Bethesda, MD 20892.
Bailey
K
K
D002986:Clinical Trials as Topic; D004646:Emphysema / Q000188:drug therapy; D006801:Humans; D008137:Longitudinal Studies; D008954:Models, Biological; D009026:Mortality; D010352:Patient Dropouts; D011336:Probability; D012107:Research Design