Dehydrobenzperidol as peroperative anti-emetic: most effective administration time.
206 female patients undergoing curettage or laparoscopy were randomized in 4 comparable groups. Group 1 did not receive dehydrobenzperidol (DHBP), group 2 was given DHBP during premedication, group 3 during induction of anesthesia and group 4 when patients presented symptoms of nausea and/or vomiting. Again, the statistical results confirm the strongly anti-emetic effects of DHBP. Because of the existing trend towards a more beneficial effect of DHBP if given during induction and the avoidance of a possible adverse reaction, administration during induction is to be preferred, at least in non-ambulatory patients.
Verhasselt
L
L
St. Lucaskliniek, Ekeren, Belgium.
Troch
E
E
Verheecke
G
G
D000932:Antiemetics / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004329:Droperidol / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009325:Nausea / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D011897:Random Allocation; D013997:Time Factors; D014839:Vomiting / Q000517:prevention & control*
D000932:Antiemetics; D004329:Droperidol