Effect of supplemental beta-carotene on luteinizing hormone released in response to gonadotropin-releasing hormone challenge in ovariectomized Holstein cows.
Thirteen lactating Holstein cows were assigned randomly to either a control or beta-carotene (600 mg/d) treatment group to determine the effect of long-term beta-carotene supplementation on releasable luteinizing hormone in response to gonadotropin-releasing hormone challenge. The experimental period was 28 wk. Milking was terminated at wk 16, ovariectomy performed at wk 20, and response to gonadotropin-releasing hormone determined at wk 27. Serum beta-carotene concentrations reflected dietary intake and were higher in the cows fed beta-carotene after 2 wk of supplementation and remained higher for the duration of the trial. Feeding supplemental beta-carotene had no effect on circulating progesterone concentration, corpora lutea size or corpora lutea progesterone concentration, or basal concentrations of luteinizing hormone, frequency, and amplitude of luteinizing hormone pulses, or the release of luteinizing hormone in response to gonadotropin-releasing hormone. Thus, pituitary responsiveness to exogenous gonadotropin-releasing hormone was not affected by feeding supplemental beta-carotene.
Wang
J Y
JY
Department of Animal Science, University of Nebraska, Lincoln 68583-0908.
Hafi
C B
CB
Larson
L L
LL
D000818:Animals; D002338:Carotenoids / Q000097:blood / Q000494:pharmacology*; D002417:Cattle / Q000502:physiology*; D003338:Corpus Luteum / Q000187:drug effects; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000378:metabolism*; D010052:Ovariectomy / Q000662:veterinary; D010902:Pituitary Gland / Q000187:drug effects / Q000378:metabolism; D019207:beta Carotene
D019207:beta Carotene; D007987:Gonadotropin-Releasing Hormone; D002338:Carotenoids; D007986:Luteinizing Hormone