title: A comparison of the conventional and the rosette method of determination of interleukin 1 (IL-1) activity. The advantages of the rosette method.
abstract: In this report we compare the conventional method of determination of IL-1 activity with a new rosette assay. Determination of IL-1 activity in the rosette assay is well correlated with the conventional method and equally sensitive. However, the rosette method is able to dissect the activity of IL-1 from IL-2 and to determine the immunotropic, optimal dose of IL-1 more accurately.
authors.affiliation: Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
authors.forename: M
authors.initials: M
authors.lastname: Zimecki
authors.forename: Z
authors.initials: Z
authors.lastname: Wieczorek
authors.forename: C W
authors.initials: CW
authors.lastname: Pierce
authors.forename: J A
authors.initials: JA
authors.lastname: Kapp
mesh_terms: D000818:Animals; D001681:Biological Assay / Q000379:methods*; D007375:Interleukin-1 / Q000032:analysis*; D051379:Mice; D008809:Mice, Inbred C3H; D013950:Thymus Gland / Q000166:cytology* / Q000187:drug effects
chemical_list: D007375:Interleukin-1