title: Computer analysis of R-looped DNA from electron micrographs.
abstract: The algorithms of the analysis of R-looped DNA molecules from electron micrographs are presented. We propose a two-dimensional R-loop distribution map with abscissa and ordinate axes corresponding to the positions of the left and right ends of the loop respectively. A transcription analysis of the hybrid plasmid pSCV1, which comprises heterologous genes from SV40 and pBR322, based on this map illustrates the program application.
authors.affiliation: Institute of Molecular Genetics, USSR Academy of Sciences, Moscow.
authors.lastname: Golovanov EuI
authors.lastname: Kalambet YuA
authors.forename: L J
authors.initials: LJ
authors.lastname: Auezova
authors.forename: A A
authors.initials: AA
authors.lastname: Alexandrov
mesh_terms: D004247:DNA / Q000648:ultrastructure*; D007091:Image Processing, Computer-Assisted; D008854:Microscopy, Electron; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA