Neurophysiological aspects of auditory hallucinations. 99mTc-(HMPAO)-SPECT investigations in patients with auditory hallucinations and normal controls--a preliminary report.
In a symptom-oriented study 17 patients suffering from chronic auditory hallucinations were investigated by means of 99mTc-HMPAO-SPECT and compared with healthy controls. The results confirm the relative frontal hypoactivity in junction with a relative hyperactivity in the basal ganglia and mesial limbic structures in both hemispheres found in a previous pilot study in auditorily hallucinating patients. Our results should fortify the symptom-oriented approach in psychiatric research.
Musalek
M
M
Department of Psychiatry, University of Vienna, Austria.
Podreka
I
I
Suess
E
E
Nutzinger
D
D
Passweg
V
V
Strobl
R
R
Walter
H
H
Baumgartner
C
C
Lesch
O M
OM
D000328:Adult; D001307:Auditory Perception / Q000502:physiology*; D001479:Basal Ganglia / Q000098:blood supply; D001921:Brain / Q000098:blood supply*; D001931:Brain Mapping / Q000379:methods; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply; D006212:Hallucinations / Q000503:physiopathology*; D006624:Hippocampus / Q000098:blood supply; D006801:Humans; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010091:Oximes; D011618:Psychotic Disorders / Q000503:physiopathology*; D012039:Regional Blood Flow; D019690:Technetium Tc 99m Exametazime; D014055:Tomography, Emission-Computed / Q000379:methods*
D009942:Organometallic Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime