title: Cathepsin B immunoreactivity is widely distributed in the rat brain.
abstract: The cellular localization and regional distribution of cathepsin B within rat CNS was revealed by immunohistochemistry using a monospecific antiserum. Cathepsin B protein was found to be widely but unevenly distributed throughout rat brain. Neurons were always cathepsin B immunoreactive. Glial elements were only occasionally immunostained. The distribution of the enzyme resembles largely that of cathepsin D.
authors.affiliation: Institute of Anatomy, Medical Academy Magdeburg, DDR.
authors.forename: H G
authors.initials: HG
authors.lastname: Bernstein
authors.forename: H
authors.initials: H
authors.lastname: Kirschke
authors.forename: B
authors.initials: B
authors.lastname: Wiederanders
authors.forename: P
authors.initials: P
authors.lastname: Kloss
authors.forename: A
authors.initials: A
authors.lastname: Rinne
authors.forename: A
authors.initials: A
authors.lastname: Dorn
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D001931:Brain Mapping; D002401:Cathepsin B / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D009474:Neurons / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D002401:Cathepsin B