title: Fluctuations in intra-ocular pressure with sleep: I. Time course of IOP increase after the onset of sleep.
abstract: Ten normal subjects slept over a series of four nights for time periods of 30 minutes, 1, 2 and 4 hours. Intra-ocular pressure (IOP) measurements were made using a non-contact tonometer before and after sleep. The subjects showed a significant increase in IOP of 3.45 mm Hg after 30 minutes of sleep and a further IOP increase thereafter to 6.41 mm Hg above baseline. Such increases in IOP after sleep in normal subjects suggest that glaucoma patients and those suspected of having glaucoma should be monitored overnight to assess their IOP control mechanisms.
authors.affiliation: Department of Optometry, Queensland Institute of Technology, Brisbane, Australia.
authors.forename: B
authors.initials: B
authors.lastname: Brown
authors.forename: P
authors.initials: P
authors.lastname: Morris
authors.forename: C
authors.initials: C
authors.lastname: Muller
authors.forename: A
authors.initials: A
authors.lastname: Brady
authors.forename: P G
authors.initials: PG
authors.lastname: Swann
mesh_terms: D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D012890:Sleep / Q000502:physiology*; D013997:Time Factors; D014065:Tonometry, Ocular