title: Severe haemolysis with the St. Jude Medical prosthesis.
abstract: The St. Jude Medical prosthesis has become one of the most widely used mechanical heart valves because of its excellent haemodynamic function. Although subclinical haemolysis has been described with this prosthesis, there has only been a single report of frank haemolysis in the absence of a paravalvular leak. We report the occurrence of severe haemolysis in five patients following St Jude Medical prosthesis implantation, four of whom had combined aortic and mitral valve replacements. In no patient could the haemolysis be attributed either to a paravalvular leak or an obvious valve malfunction.
authors.affiliation: Department of Cardiac Surgery, Royal Infirmary, Glasgow, Scotland, UK.
authors.forename: D P
authors.initials: DP
authors.lastname: Taggart
authors.forename: T J
authors.initials: TJ
authors.lastname: Spyt
authors.forename: D J
authors.initials: DJ
authors.lastname: Wheatley
authors.forename: J
authors.initials: J
authors.lastname: Fisher
mesh_terms: D000368:Aged; D001002:Anuria / Q000209:etiology; D001021:Aortic Valve; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006456:Hemoglobinuria / Q000209:etiology; D006461:Hemolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D011475:Prosthesis Failure