A systematic study of patterns of hydration in nucleic acids:(I) guanine and cytosine.
The hydration sites of guanine and cytosine are defined by examination of the crystal structures of bases, nucleosides, nucleotides, and three dinucleoside phosphate salts. The patterns of hydration for two guanine and cytosine containing oligonucleotides are then predicted. The relationship between these structural motifs and thermodynamic parameters is discussed.
Berman
H M
HM
Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA 19111.
Sowri
A
A
Ginell
S
S
Beveridge
D
D
D003461:Crystallography; D003596:Cytosine; D006147:Guanine; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides; D013816:Thermodynamics; D014867:Water
D009841:Oligonucleotides; D014867:Water; D006147:Guanine; D003596:Cytosine