Early and late determinants of survival after surgery of left ventricular aneurysm.
The fate of 103 patients consecutively operated upon for chronic left ventricular aneurysm between 1978 and 1986 was examined with a multivariate statistical approach to verify the operative indications and results. In the early risk phase, up to 39 days after operation, 15 patients (15%) died. Mortality was mostly due to a low output syndrome and was significantly related to older age and to functional (NYHA) and anginal (CCS) class. In the late risk phase, starting 1.9 years after surgery, 9 patients died (10%) and the significant risk factors were anterior aneurysm and older age at operation. Actuarial survival curves showed 82% survival at 5 years and 61% at 9.5 years. In 25 patients older than 50 years and with an anterior aneurysm, these rates were 51% and 34%, respectively. Improved functional class was observed in 87% of the patients interviewed, but 30% complained of angina or new infarctions. Survival free of ischemia was 64% at 5 years and 13% at 9.5 years. This development of ischemic recurrences was significantly related to older age and to incomplete revascularization despite multiple grafts. These results suggest modification of the grafting policy and of the techniques of repair in identified high-risk subsets.
Rizzoli
G
G
Institute of Cardiovascular Surgery, University of Padova, Italy.
Bellotto
F
F
Gallucci
V
V
Gemelli
M
M
Brumana
T
T
Mazzucco
A
A
Rubino
M
M
Bassan
L
L
Stritoni
P
P
D000206:Actuarial Analysis; D000367:Age Factors; D002423:Cause of Death; D005260:Female; D006322:Heart Aneurysm / Q000145:classification / Q000401:mortality / Q000601:surgery*; D006352:Heart Ventricles / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012008:Recurrence; D012307:Risk Factors; D016019:Survival Analysis