Anaerobic metabolism of the L-rhamnose fermentation product 1,2-propanediol in Salmonella typhimurium.
When grown anaerobically on L-rhamnose, Salmonella typhimurium excreted 1,2-propanediol as a fermentation product. Upon exhaustion of the methyl pentose, 1,2-propanediol was recaptured and further metabolized, provided the culture was kept under anaerobic conditions. n-Propanol and propionate were found in the medium as end products of this process at concentrations one-half that of 1,2-propanediol. As in Klebsiella pneumoniae (T. Toraya, S. Honda, and S. Fukui, J. Bacteriol. 139:39-47, 1979), a diol dehydratase which transforms 1,2-propanediol to propionaldehyde and the enzymes involved in a dismutation that converts propionaldehyde to n-propanol and propionate were induced in S. typhimurium cultures able to transform 1,2-propanediol anaerobically.
Obradors
N
N
Department of Biochemistry, Faculty of Pharmacy, University of Barcelona, Pedralbes, Spain.
Badía
J
J
Baldomà
L
L
Aguilar
J
J
D000433:1-Propanol / Q000378:metabolism; D000447:Aldehydes / Q000378:metabolism; D000693:Anaerobiosis; D004790:Enzyme Induction; D005285:Fermentation; D011408:Propanediol Dehydratase / Q000096:biosynthesis; D011422:Propionates / Q000378:metabolism; D011409:Propylene Glycols / Q000378:metabolism*; D012210:Rhamnose / Q000378:metabolism*; D012486:Salmonella typhimurium / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*
D000447:Aldehydes; D011422:Propionates; D011409:Propylene Glycols; D000433:1-Propanol; C005556:propionaldehyde; D011408:Propanediol Dehydratase; D012210:Rhamnose