title: [Results of the use of topical diosmin (venosmine) in the treatment of acute hemorrhoid pathology].
abstract: There is still much discussion about the pharmacological treatment of certain symptoms caused by haemorrhoids and their complications. In 1986 topical treatment with Diosmina ointment was used on 50 patients (33 males, 17 females) with grade 1, 2, 3 or 4 haemorrhoids featuring strangulation and thrombosis. Patients who had previously been given other treatment were excluded from the study. The efficacy of the treatment was assessed by a simple method previously used by others which involves scoring (0-3) the major symptoms of the condition (bleeding, oedema, erythema, pain, itching) according to severity. The drug was most effective on oedema and erythema, producing 75% and 73% improvements as assessed in three consecutive weekly visits. These results confirm the value of Diosmina in the topical treatment of acute haemorrhoids. In particular the treatment is very well tolerated and produces no unwanted side effects if properly used.
authors.affiliation: Università degli Studi di Milano, Istituto di Chirurgia Generale e di Oncologia Chirurgica.
authors.forename: A
authors.initials: A
authors.lastname: Tajana
authors.forename: P
authors.initials: P
authors.lastname: Boccasanta
authors.forename: G
authors.initials: G
authors.lastname: Micheletto
authors.forename: A
authors.initials: A
authors.lastname: Orio
mesh_terms: D000287:Administration, Topical; D002986:Clinical Trials as Topic; D004145:Diosmin / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005419:Flavonoids / Q000627:therapeutic use*; D006484:Hemorrhoids / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011897:Random Allocation; D013927:Thrombosis / Q000188:drug therapy
chemical_list: D005419:Flavonoids; D004145:Diosmin
vernacular_title: Risultati dell'uso della diosmina (venosmine) per applicazione topica nel trattamento della patologia acuta emorroidaria.