Dyskeratosis congenita: report of a case and review of the literature.
A case of dyskeratosis congenita in a 10-year-old white boy is reported. The triad of oral leukoplakia, nail dystrophy, and skin pigmentation was present. Other associated anomalies included dysphagia and varied immunoglobulin levels, although there was no evidence of anemia, pancytopenia, and ocular involvement. Since it may be associated with future malignant change, dyskeratosis congenita should be considered in all cases in which an obscure white lesion exists in the mouth.
Ogden
G R
GR
Department of Dental Surgery, University of Dundee, Scotland.
Connor
E
E
Chisholm
D M
DM
D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D007972:Leukoplakia, Oral / Q000151:congenital*; D008297:Male; D009260:Nail Diseases / Q000151:congenital*; D010859:Pigmentation Disorders / Q000151:congenital*; D013577:Syndrome; D014062:Tongue Neoplasms / Q000151:congenital*