[Effect of tubocurarine on the quantum release of acetylcholine during the infrequent stimulation of a motor nerve].
The effect of d-tubocurarine on quantal release of acetylcholine elicited with nerve pulses 0.5 to 1 Hz was studied in the frog isolated cutaneous pectoris muscle. The muscle twitches were prevented either by lowering Ca++ and raising Mg++ or by cutting the muscle fibers. In none of these cases d-tubocurarine (3.10(-7) to 5.10(-6) M) was found to affect quantal release of acetylcholine.
Grigor'ev
V M
VM
Danilov
A F
AF
Skliarov
A I
AI
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D002118:Calcium / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D008274:Magnesium / Q000494:pharmacology; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D009045:Motor Endplate / Q000187:drug effects* / Q000502:physiology; D009119:Muscle Contraction / Q000187:drug effects; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000502:physiology; D011896:Rana temporaria; D014403:Tubocurarine / Q000494:pharmacology*
D008274:Magnesium; D000109:Acetylcholine; D002118:Calcium; D014403:Tubocurarine
O vliianii tubokurarina na kvantovoe vydelenie atsetilkholina pri redkoĭ stimuliatsii dvigatel'nogo nerva.