title: The effects of calcium on water transport.
abstract: Some critical level of calcium appears to be necessary for maximum expression of the hydroosmotic effect of vasopressin: both maneuvers which elevate cell calcium or activate calcium-dependent enzymes and maneuvers which diminish cell calcium or inhibit its effect diminish vasopressin-stimulated water flow. It would thus appear that cell calcium might well be maintained at some optimum level for mediating vasopressin-stimulated water flow across epithelia. At the same time, there is considerable evidence supporting vasopressin-elicited alterations in cell calcium and phospholipid metabolism; however, the linkage between these alterations and any eventual effects on water permeability has not yet been established with confidence.
authors.affiliation: Department of Medicine, Albert Einstein College of Medicine, Bronx, N.Y.
authors.forename: S D
authors.initials: SD
authors.lastname: Levine
mesh_terms: D000818:Animals; D001834:Body Water / Q000187:drug effects / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism / Q000502:physiology*; D002121:Calcium Channel Blockers / Q000494:pharmacology; D002147:Calmodulin / Q000502:physiology; D006801:Humans; D010743:Phospholipids / Q000378:metabolism; D014667:Vasopressins / Q000494:pharmacology
chemical_list: D002121:Calcium Channel Blockers; D002147:Calmodulin; D010743:Phospholipids; D014667:Vasopressins; D002118:Calcium