title: LHRH-immunoreactive structures in the sheep brain.
abstract: Neural structures containing luteinizing hormone-releasing hormone (LHRH) are characterized in adult ewe and female lamb brains. Three anti-LHRH antisera are used in an immunofluorescent or immunoperoxidase method. On our preparations, all three gave the same results, expressed as number of labelled cells (about 2500 in a whole brain). It was found that 95% of the LHRH-immunoreactive cells are located in the preoptico-hypothalamic area, where cell bodies are localized mainly (50%) in the area surrounding the organum vasculosum of the lamina terminalis (OVLT); they are also found in a more anterior section of the medial part of the olfactory tubercle and the medial septum (14%), in a more posterior situation in the anterior and lateral hypothalamus (16%), and in the mediobasal hypothalamus (15%). Fibres originating in various part of the whole preoptico-hypothalamic group reach the OVLT and the median eminence. The remaining cells (5%) and fibres are found in various tel-, di-, and mesencephalic areas.
authors.affiliation: Physiologie de la Reproduction, INRA Nouzilly, Monnaie, France.
authors.forename: M
authors.initials: M
authors.lastname: Caldani
authors.forename: M
authors.initials: M
authors.lastname: Batailler
authors.forename: J C
authors.initials: JC
authors.lastname: Thiéry
authors.forename: M P
authors.initials: MP
authors.lastname: Dubois
mesh_terms: D000818:Animals; D001921:Brain / Q000276:immunology / Q000378:metabolism*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000276:immunology / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism; D007150:Immunohistochemistry; D009434:Neural Pathways / Q000378:metabolism; D011301:Preoptic Area / Q000378:metabolism; D012756:Sheep
chemical_list: D007987:Gonadotropin-Releasing Hormone