title: Enterohemolysin, a new type of hemolysin produced by some strains of enteropathogenic E. coli (EPEC).
abstract: 42 Escherichia coli O26 strains which had been isolated at geographically different places and over a long time period were examined for hemolysin synthesis. 17 of these were found to be hemolysin-negative, nine strains were found to produce plasmid encoded alpha-hemolysin and 16 strains were shown to produce a phenotypically different hemolysin. This new type of hemolysin was called enterohemolysin and found to be genetically and immunologically non-related with the already described E. coli alpha-hemolysin. Enterohemolytic E. coli were not found in feces of 200 healthy infants under the age of two years. However, four E. coli O111 strains, one O121:H- and one O25:K5:H- strain, all from infants with diarrhoea were also enterohemolysin producers.
authors.affiliation: Robert Koch-Institut des Bundesgesundheitsamtes, Berlin, West Germany.
authors.forename: L
authors.initials: L
authors.lastname: Beutin
authors.forename: J
authors.initials: J
authors.lastname: Prada
authors.forename: S
authors.initials: S
authors.lastname: Zimmermann
authors.forename: R
authors.initials: R
authors.lastname: Stephan
authors.forename: I
authors.initials: I
authors.lastname: Orskov
authors.forename: F
authors.initials: F
authors.lastname: Orskov
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D004926:Escherichia coli / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D006460:Hemolysin Proteins / Q000302:isolation & purification* / Q000633:toxicity; D006801:Humans; D013045:Species Specificity; D014709:Vero Cells
chemical_list: D006460:Hemolysin Proteins