Prenatal diagnosis of severe urinary tract anomalies improves renal function and growth.
The clinical course of 14 children with bilateral renal disease diagnosed on prenatal ultrasound examination (prenatal group) was compared with a control group of 14 children who presented postnatally (postnatal group). The children in the prenatal group had earlier evaluation and treatment of their renal disease and fewer complications prior to diagnosis. Prenatally diagnosed children had a lower incidence of reduced renal function and better growth than matched controls.
Murphy
J I
JI
Department of Pediatrics, UCSD School of Medicine.
Kaplan
G W
GW
Packer
M G
MG
Griswold
W R
WR
Mendoza
S A
SA
Reznik
V M
VM
D002675:Child, Preschool; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007668:Kidney / Q000254:growth & development* / Q000502:physiology; D007674:Kidney Diseases / Q000175:diagnosis* / Q000503:physiopathology; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013997:Time Factors; D014551:Urinary Tract / Q000002:abnormalities*