title: Hereditary motor neuron disease.
abstract: Nine cases of motor neuron disease (amyotrophic lateral sclerosis) in one family over 3 generations are presented. In 2 instances the disease was transmitted from parent to child. Several of the patients were first cousins. There was no skipping of a generation. The positive family history had been overlooked by several neurologists, although they had enquired for it. Familial motor neuron disease accounts for at least 10% of cases of this disorder.
authors.affiliation: Department of Neurology, Royal North Shore Hospital, Sydney, NSW.
authors.forename: G
authors.initials: G
authors.lastname: Selby
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D015417:Hereditary Sensory and Motor Neuropathy / Q000235:genetics* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree