title: [Endogenous digoxin-like substance level in essential arterial hypertension, renal failure and acromegaly].
abstract: The endogenous digoxin-like substance seems to play an important role in the aetiology and pathogenesis of essential and secondary hypertension. Immunoreactive digoxin-like substance was determined in 52 subjects: 17 healthy ones, 15 patients with essential hypertension, 10 cases of chronic renal failure and 10 patients with acromegaly. The substance was not found in healthy subjects, in acromegaly and essential hypertension. In chronic renal failure detectable concentrations of the substance were observed but they showed no correlation with the creatinine level and other clinical data.
authors.forename: P
authors.initials: P
authors.lastname: Soszyński
authors.forename: J
authors.initials: J
authors.lastname: Słowińska-Srzednicka
authors.forename: M
authors.initials: M
authors.lastname: Wierzbicki
mesh_terms: D000172:Acromegaly / Q000097:blood*; D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D002298:Cardenolides; D004077:Digoxin; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012503:Saponins
chemical_list: D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin
vernacular_title: Stezenie endogennej substancji digoksyno-podobnej w samoistnym nadcisnieniu tetniczym, niewydolności nerek i akromegalii.