Serotonin antagonism in the treatment of systemic hypertension: the role of ketanserin.
Serotonin has various hemodynamic effects, and may play a role in systemic hypertension. Ketanserin is a specific S2 serotonergic receptor blocker with possible adrenergic blocking activities that has clinical utility in the treatment of hypertension. The drug may have particular advantages for various patient populations.
Frishman
W H
WH
Albert Einstein College of Medicine, Bronx, New York.
Okin
S
S
Huberfeld
S
S
D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D007650:Ketanserin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D010975:Platelet Aggregation Inhibitors
D010975:Platelet Aggregation Inhibitors; D007650:Ketanserin