[Deficiency of the 6th component of complement. Recurrent meningococcal and streptococcal meningitis].
A 39-year old male patient with a history of four episodes of meningitis (two of them due to Neisseria meningitidis) since the age of 12 developed meningitis caused by an ungroupable streptococcus. Deficiency of the sixth component of complement was discovered, making this the ninth case of recurrent meningitis associated with C6 deficiency. Streptococcal meningitis had never been reported in such cases.
Vincent
D
D
Clinique neurologique, Groupe Hospitalier Pitié-Salpêtrière.
Zemrag
S
S
Rancurel
G
G
Buge
A
A
D000328:Adult; D003183:Complement C6 / Q000172:deficiency*; D006801:Humans; D008297:Male; D008581:Meningitis / Q000209:etiology*; D008585:Meningitis, Meningococcal / Q000209:etiology; D012008:Recurrence; D013290:Streptococcal Infections / Q000209:etiology
D003183:Complement C6
Déficit en sixième composant du complément. Méningites récidivantes à méningocoque et à streptocoque.