title: Evaluation of Chemstrip LN in a male geriatric population.
abstract: A dipstick method for bacteriologic screening of urine using a combination of leukocyte esterase and nitrite indicators, Chemstrip LN, was evaluated in a male inpatient geriatric population. Three hundred seventy-five urine samples from 198 symptomatic patients (age range, 45 to 98 years; mean, 69.6) were tested by LN and cultured using standard methods. LN showed 169 negatives, but in 7 of these cases, the culture was positive (greater than or equal to 5 X 10(4) col/mL). Organisms recovered from these cultures were Candida (not albicans), Group B Streptococcus, Staphylococcus aureus, and in four cases, Pseudomonas aeruginosa. In the four cases of missed Pseudomonas the patients were receiving aminoglycoside therapy for 2 to 6 days and/or drugs that dye the urine. Despite the fact that many patients were on medications known to interfere with the test strips, the negative predictive value was still 96.0% showing that the strips may be suitable for use with this population given the understanding that certain antibiotics and/or substances that dye the urine may give false negative results.
authors.affiliation: University of Illinois School of Clinical Medicine, Urbana/Champaign.
authors.forename: S M
authors.initials: SM
authors.lastname: Gelbart
authors.forename: M M
authors.initials: MM
authors.lastname: Prabhudesai
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001431:Bacteriological Techniques / Q000295:instrumentation*; D001437:Bacteriuria / Q000175:diagnosis; D002408:Catheters, Indwelling; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D006801:Humans; D008297:Male; D008875:Middle Aged; D011934:Reagent Strips; D014556:Urine / Q000382:microbiology*
chemical_list: D011934:Reagent Strips