[Magnetic resonance study of renal function. Preliminary evaluation].
The amount of functioning renal parenchyma can be estimated by MRI by considering the ratio between the mean intensities of cortical and medullar zones of the kidney. Fifty-six patients and 5 healthy volunteers were studied by MRI in our department. Scanning was performed with a superconductive magnet system operating at 0.5 Tesla. Pulse sequence was Spin-Echo with TR 300/TE 30 ms. The cortico-medullary ratio (CMR) and differentiation (CMD) were standardized and related with creatine blood levels. CMR data ranged from 1.05 to 3.00, while CMD data ranged from 0.04 to 0.50. High values (good cortico-medullary contrast) were observed in subjects with normal renal function. Patients with renal diseases had low CMR and CMD, proportionally to the degree of renal failure, as proved by laboratory findings. Our preliminary study seems to demonstrate that MRI is an useful technique in the follow-up of patients with chronic renal disease.
Beomonte Zobel
B
B
Università degli Studi, Cattedra di Radiologia, l'Aquila.
Giammarile
F
F
Di Renzi
P
P
Matarese
A
A
Masciocchi
C
C
Gallucci
M
M
Splendiani
G
G
Casciani
C U
CU
Passariello
R
R
D003404:Creatinine / Q000097:blood; D005069:Evaluation Studies as Topic; D006801:Humans; D007668:Kidney / Q000502:physiology*; D007672:Kidney Cortex / Q000502:physiology; D007674:Kidney Diseases / Q000175:diagnosis / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000503:physiopathology; D007679:Kidney Medulla / Q000502:physiology; D016030:Kidney Transplantation; D008279:Magnetic Resonance Imaging; D009392:Nephrectomy
D003404:Creatinine
Studio della funzionalità renale con risonanza magnetica. Valutazioni preliminari.