The use of monoclonal antibodies in fine needle aspiration biopsy of the renal transplant.
This report deals with the clinical application of monoclonal antibody techniques to fine needle aspiration biopsy (FNAB) of the renal transplant. The technique was deemed to be quite helpful in corroborating cell type analysis made by classical cytochemistry (Giemsa staining), and determination of the nature of the lymphoid subset at play in rejection. The role of activation marker analysis and class 2 alloantigen analysis in particular for rejection was also discussed.
Helderman
J H
JH
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas 75235-9030.
D000911:Antibodies, Monoclonal; D001707:Biopsy, Needle / Q000379:methods; D006084:Graft Rejection; D006681:HLA-D Antigens / Q000032:analysis; D006801:Humans; D007668:Kidney / Q000276:immunology / Q000473:pathology*; D016030:Kidney Transplantation; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology
D000911:Antibodies, Monoclonal; D006681:HLA-D Antigens