title: [Panencephalopathy of the Creutzfeldt-Jakob disease type].
abstract: Creutzfeldt-Jakob disease (CJD) occurring in later life has a duration of about one year. Gait disturbance, myoclonic jerks, dementia and akinetic mutism occur. Post-mortem examination of the brain shows nerve cell loss, gliosis and spongiform changes of the grey matter. Clinical and neuropathological features of a case of the panencephalopathic type of CJD, with additional extensive degeneration of the cerebral white matter, are described. The panencephalopathic type of CJD is characterized clinically by a longer duration and a biphasic course.
authors.affiliation: Institut für Neuropathologie, Klinikum Steglitz der Freien Universität Berlin.
authors.forename: H J
authors.initials: HJ
authors.lastname: Gertz
authors.forename: G
authors.initials: G
authors.lastname: Stoltenburg
authors.forename: F
authors.initials: F
authors.lastname: Cruz-Sanchez
authors.forename: J
authors.initials: J
authors.lastname: Lafuente
authors.forename: R
authors.initials: R
authors.lastname: Schopol
mesh_terms: D000328:Adult; D001284:Atrophy; D001921:Brain / Q000473:pathology*; D002540:Cerebral Cortex / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000473:pathology*; D005260:Female; D006801:Humans; D009186:Myelin Sheath / Q000648:ultrastructure; D009457:Neuroglia / Q000473:pathology; D009474:Neurons / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology; D014057:Tomography, X-Ray Computed
vernacular_title: Der panenzephalopathische Typ der Creutzfeldt-Jakob-Krankheit.