Haemopoietic growth factors.
Erythropoietin, GM-colony-stimulating factor and G-colony-stimulating factor are the first recombinant haemopoietic growth factors to reach clinical use. There are a number of additional haemopoietic regulators that have now been cloned and are being mass-produced with a view to clinical use. The next decade should witness exciting advances in the clinical treatment of haematological diseases and infections that will be comparable with those that were seen last with the introduction of effective treatments for pernicious anaemia.
Metcalf
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Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Vic.
D000818:Animals; D003115:Colony-Stimulating Factors / Q000502:physiology* / Q000627:therapeutic use; D006098:Granulocytes / Q000166:cytology; D006402:Hematologic Diseases / Q000628:therapy*; D006801:Humans; D007377:Interleukin-3 / Q000502:physiology* / Q000627:therapeutic use; D008264:Macrophages / Q000166:cytology
D003115:Colony-Stimulating Factors; D007377:Interleukin-3