Beta 2-sympathomimetic activation as a cause of posthypoglycemic glucose intolerance.
Posthypoglycemic glucose intolerance is related to counter-regulatory hormones. We have tested the role of the beta 2-sympathomimetic activity of the catecholamines in healthy volunteers. beta 2-stimulation with fenoterol for 25 minutes caused glucose intolerance and insulin resistance for 4 hours. This suggests that the beta 2-sympathomimetic activity induces glucose intolerance after an episode of hypoglycemia.
Petersen
K G
KG
Abteilung für klinische Endokrinologie, Albert-Ludwigs-Universität, Freiburg, Germany.
Kerp
L
L
D001786:Blood Glucose / Q000032:analysis; D005280:Fenoterol / Q000494:pharmacology*; D005951:Glucose Tolerance Test; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced*; D007328:Insulin / Q000097:blood / Q000494:pharmacology*; D008297:Male
D001786:Blood Glucose; D007328:Insulin; D005280:Fenoterol