title: Acute unilateral obstruction of ureter. Disparity in divided renal function calculated from 131I-hippuran and 99mTc-DTPA renography.
abstract: Fifteen patients with acute unilateral obstruction of ureter and 30 control patients were studied with simultaneous 131I-Hippuran and 99mTc-DTPA gamma camera renography. In severe outflow obstruction the relative function of the obstructed kidney was higher when calculated with Hippuran than with DTPA. No difference was found in the control subjects. This means that the glomerular filtration rate of an obstructed kidney may be relatively more reduced than the renal blood flow. Therefore, measurement of the single kidney fraction of total glomerular filtration rate has to be calculated with a glomerular filtered tracer, e.g., 99mTc-DTPA.
authors.affiliation: Department of Clinical Physiology, Frederiksberg Hospital, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Rehling
authors.forename: J O
authors.initials: JO
authors.lastname: Lund
authors.forename: M L
authors.initials: ML
authors.lastname: Møller
authors.forename: P
authors.initials: P
authors.lastname: Lange
authors.forename: J
authors.initials: J
authors.lastname: Gammelgaard
authors.forename: E
authors.initials: E
authors.lastname: Clausen
authors.forename: J
authors.initials: J
authors.lastname: Trap-Jensen
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007465:Iodohippuric Acid; D007668:Kidney / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D011866:Radioisotope Renography; D016284:Technetium Tc 99m Pentetate; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging*
chemical_list: D009942:Organometallic Compounds; D007465:Iodohippuric Acid; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate