Chromosomal localization of the human interleukin 1 alpha (IL-1 alpha) gene.
The human interleukin 1 alpha gene was assigned to chromosome 2 using Southern transfer analysis of human-rodent somatic cell hybrid DNAs. The gene was regionally localized to 2q12-21 using in situ hybridization to metaphase chromosomes. These results indicate that the IL-1 alpha gene maps to the same general region on the long arm of chromosome 2 as the IL-1 beta gene, which has been previously assigned.
Modi
W S
WS
Biological Carcinogenesis Development Program, Frederick Cancer Research Facility, Maryland 21701-1013.
Masuda
A
A
Yamada
M
M
Oppenheim
J J
JJ
Matsushima
K
K
O'Brien
S J
SJ
D000818:Animals; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D004247:DNA / Q000235:genetics; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D007375:Interleukin-1 / Q000235:genetics*; D007621:Karyotyping; D008214:Lymphocytes / Q000166:cytology; D009693:Nucleic Acid Hybridization
D007375:Interleukin-1; D004247:DNA