Severe hypophosphataemia induced by glucose-insulin-potassium therapy. A case report and proposal for altered protocol.
A case is described where severe hypophosphataemia was induced by a widely used protocol for glucose-insulin-potassium (GIK) infusion. Hypophosphataemia was found to be a universal sequel to the use of this infusion. A new regimen for administering this agent was designed, and shown to lack the potentially serious side effect of phosphate depletion.
Marwick
T H
TH
Department of Cardiology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Woodhouse
S P
SP
D000368:Aged; D003327:Coronary Disease / Q000097:blood / Q000628:therapy*; D005947:Glucose / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D007328:Insulin / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D009203:Myocardial Infarction / Q000097:blood / Q000628:therapy*; D010710:Phosphates / Q000097:blood*; D011188:Potassium / Q000008:administration & dosage / Q000009:adverse effects
D007328:Insulin; D010710:Phosphates; C030396:glucose-insulin-potassium cardioplegic solution; D005947:Glucose; D011188:Potassium