title: Squamous cell cancer of the liver arising from a solitary benign nonparasitic hepatic cyst.
abstract: A case of squamous cell carcinoma arising from a solitary benign nonparasitic hepatic cyst (SBNHC) causing bile duct obstruction is presented. A review of the literature regarding SBNHC suggests that, although these lesions may appear benign, they may also undergo metaplastic and subsequent malignant transformation. This appears to be particularly true when the SBNHC is lined with squamous epithelium. Once squamous cell carcinoma arises from one of these lesions, the prognosis is extremely grave, despite all forms of surgical and medical management.
authors.affiliation: Department of Surgery, Veterans Administration Medical Center, Ann Arbor, Michigan.
authors.forename: M J
authors.initials: MJ
authors.lastname: Lynch
authors.forename: M K
authors.initials: MK
authors.lastname: McLeod
authors.forename: L
authors.initials: L
authors.lastname: Weatherbee
authors.forename: J R
authors.initials: JR
authors.lastname: Gilsdorf
authors.forename: K S
authors.initials: KS
authors.lastname: Guice
authors.forename: F E
authors.initials: FE
authors.lastname: Eckhauser
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D001651:Cholestasis, Extrahepatic / Q000209:etiology; D003560:Cysts / Q000150:complications / Q000473:pathology*; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000473:pathology*; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged