title: Phosgene as a derivatizing reagent prior to gas and liquid chromatography.
abstract: The use of phosgene as a derivatizing agent for bifunctional compounds prior to gas and liquid chromatographic analysis is reviewed. Applications include gas chromatographic determinations of metoprolol and its metabolites in biological fluids, enantiomeric separations of beta-blocking drugs and sympathomimetic agents on a chiral stationary phase and liquid chromatographic enantiomer separations.
authors.affiliation: Analytical Chemistry, AB Hässle, Mölndal, Sweden.
authors.forename: O
authors.initials: O
authors.lastname: Gyllenhaal
authors.forename: J
authors.initials: J
authors.lastname: Vessman
mesh_terms: D000818:Animals; D002849:Chromatography, Gas; D002853:Chromatography, Liquid; D006801:Humans; D007202:Indicators and Reagents; D010705:Phosgene
chemical_list: D007202:Indicators and Reagents; D010705:Phosgene