title: A family showing apparent X linked inheritance of both anencephaly and spina bifida.
abstract: A family is reported which includes five males, two with spina bifida, two sibs with anencephaly, and one with both high and low spinal lesions. The affected subjects came from four sibships in three generations. The mode of inheritance of these neural tube defects is consistent with X linkage.
authors.affiliation: Blood Bank, National University Hospitals, Reykjavik, Iceland.
authors.forename: O
authors.initials: O
authors.lastname: Jensson
authors.forename: A
authors.initials: A
authors.lastname: Arnason
authors.forename: H
authors.initials: H
authors.lastname: Gunnarsdottir
authors.forename: I
authors.initials: I
authors.lastname: Petursdottir
authors.forename: R
authors.initials: R
authors.lastname: Fossdal
authors.forename: S
authors.initials: S
authors.lastname: Hreidarsson
mesh_terms: D000328:Adult; D000757:Anencephaly / Q000235:genetics*; D005260:Female; D005808:Genes, Recessive; D008040:Genetic Linkage; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007055:Iceland; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D016136:Spina Bifida Occulta / Q000235:genetics*; D014960:X Chromosome
chemical_list: D006680:HLA Antigens