title: The physiology of spontaneous and mechanical ventilation.
abstract: This article provides both an overview of normal ventilation and gas exchange during spontaneous breathing and a review of the alterations of pulmonary physiology that occur with the institution of mechanical ventilation.
authors.affiliation: Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor.
authors.forename: J W
authors.initials: JW
authors.lastname: Kreit
authors.forename: W L
authors.initials: WL
authors.lastname: Eschenbacher
mesh_terms: D006801:Humans; D008954:Models, Biological; D011659:Pulmonary Gas Exchange; D012123:Pulmonary Ventilation; D012119:Respiration; D012121:Respiration, Artificial; D012143:Respiratory Physiological Phenomena