A progress report on the New Zealand Multicentre Parkinson's disease trial. A comparison of low-dose treatment with bromocriptine or L-dopa.
A short-term and long-term prospective trial comparing 'low-dose' bromocriptine with L-dopa in the de novo treatment of Parkinson's disease began in 1983. One hundred and twenty-eight patients entered the trial by early 1987. One hundred and seven have remained on one drug. Statistical analysis indicates that a hundred patients in each treatment group will be necessary to avoid a type II statistical error in the comparison of these treatments.
Wallis
W E
WE
Department of Neurology, Auckland Hospital, New Zealand.
D001971:Bromocriptine / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage / Q000627:therapeutic use*; D010300:Parkinson Disease / Q000188:drug therapy*; D011446:Prospective Studies
D001971:Bromocriptine; D007980:Levodopa