Stimulation of intrinsic prostacyclin synthesis and inhibition of thromboxane production to minimize cyclosporine nephrotoxicity.
Teraoka
S
S
Department of Surgery, Tokyo Women's Medical College, Japan.
Sanaka
T
T
Takahashi
K
K
Toma
H
H
Yamaguchi
Y
Y
Yagisawa
T
T
Tanabe
K
K
Sato
H
H
Matsumura
O
O
Nakajima
I
I
D010129:4-Aminobenzoic Acid / Q000494:pharmacology*; D015121:6-Ketoprostaglandin F1 alpha / Q000378:metabolism; D062365:Aminobenzoates / Q000494:pharmacology*; D000818:Animals; D003404:Creatinine / Q000097:blood; D003524:Cyclosporins / Q000037:antagonists & inhibitors*; D015232:Dinoprostone; D011464:Epoprostenol / Q000096:biosynthesis; D007328:Insulin / Q000097:blood; D007515:Islets of Langerhans / Q000033:anatomy & histology / Q000187:drug effects; D007668:Kidney / Q000033:anatomy & histology / Q000187:drug effects*; D008358:Mannose / Q000031:analogs & derivatives* / Q000494:pharmacology; D011458:Prostaglandins E / Q000378:metabolism; D051381:Rats; D013929:Thromboxane B2 / Q000378:metabolism; D062366:para-Aminobenzoates
D062365:Aminobenzoates; D003524:Cyclosporins; D007328:Insulin; D011458:Prostaglandins E; D062366:para-Aminobenzoates; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; C055108:4-aminobenzoic acid-N-mannoside; D003404:Creatinine; D011464:Epoprostenol; D015232:Dinoprostone; D008358:Mannose; D010129:4-Aminobenzoic Acid