Fluorocarbon (FC-43) in augmentation of tissue oxygen and its experimental use for flap survival.
The tissue PO2 level in the skin of rats injected with fluorocarbon (FC-43) was measured by the microelectrode method and by a transcutaneous monitor. It was found that the tissue PO2 in the animals injected with FC-43 was two to three times higher than that of the control group. Neither the administration of FC-43 nor the inhalation of systemic oxygen improved flap survival in the rats.
Yoshimura
Y
Y
Department of Plastic and Reconstructive Surgery, Fujitagakuen-Hokeneisei University, School of Medicine, Aichi, Japan.
Nakajima
T
T
Kami
T
T
D000818:Animals; D001802:Blood Substitutes / Q000494:pharmacology*; D005466:Fluorocarbons / Q000494:pharmacology*; D006085:Graft Survival / Q000187:drug effects* / Q000502:physiology; D008297:Male; D008991:Monitoring, Physiologic; D010101:Oxygen Consumption / Q000187:drug effects*; D051381:Rats; D013524:Surgical Flaps / Q000379:methods* / Q000502:physiology
D001802:Blood Substitutes; D005466:Fluorocarbons; C008807:perfluorotributylamine