Tetracycline-induced renal hypophosphatemia in a patient with a syndrome of inappropriate secretion of antidiuretic hormone.
A third case of acquired phosphate diabetes associated with a syndrome of inappropriate secretion of antidiuretic hormone (SIADH), related to a pulmonary tuberculosis, is reported. Renal hypophosphatemia in this patient was caused by the erroneous intake of 1 g doxycycline. It is likely that the selective nephrotoxicity in these 3 patients with SIADH was induced by tetracycline.
Decaux
G
G
Department of Internal Medicine, Erasmus University Hospital, Brussels, Belgium.
D004318:Doxycycline / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000097:blood / Q000150:complications*; D008875:Middle Aged; D010710:Phosphates / Q000097:blood*; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy
D010710:Phosphates; D004318:Doxycycline