title: Direct separation of drug enantiomers by high-performance liquid chromatography with chiral stationary phases.
abstract: The development of chiral stationary phases for HPLC has resulted in renewed interest in methods for the separation of drug enantiomers. This paper provides a brief overview of some of the more recent approaches to the direct resolution of drug enantiomers by HPLC with particular emphasis on their quantification in biological fluids.
authors.affiliation: Department of Pharmacy, General Infirmary, Leeds, Yorkshire, U.K.
authors.forename: A C
authors.initials: AC
authors.lastname: Mehta
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004364:Pharmaceutical Preparations / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D004364:Pharmaceutical Preparations