title: Subarachnoid anaesthesia produced by hyperbaric lignocaine in elderly patients. Prolongation of effect with adrenaline.
abstract: The effects of adrenaline on the duration of spinal anaesthesia induced with hyperbaric lignocaine were investigated in 60 elderly patients in a double-blind study. Each patient received 5% lignocaine 2 ml in 7.5% dextrose to which was added physiological saline 1 ml, 1:1000 adrenaline 0.2 ml (0.2 mg) plus normal saline 0.8 ml, or adrenaline 0.4 ml with normal saline 0.6 ml. The duration of sensory block (measured by two- and four-segment regression times, and times to regression to T12 and L2 dermatomes) was prolonged significantly by both doses of adrenaline. The addition of adrenaline also produced a significant increase in the duration of complete motor block.
authors.affiliation: Department of Anaesthesiology, General Hospital, Chalon-sur-Saône, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Racle
authors.forename: A
authors.initials: A
authors.lastname: Benkhadra
authors.forename: J Y
authors.initials: JY
authors.lastname: Poy
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000775:Anesthesia, Spinal; D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004837:Epinephrine / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage* / Q000494:pharmacology; D008297:Male; D009046:Motor Neurons / Q000187:drug effects; D013046:Specific Gravity; D013997:Time Factors
chemical_list: D008012:Lidocaine; D004837:Epinephrine