title: Transposition of the great arteries with intact ventricular septum. Arterial switch in the first month of life.
abstract: Twenty-three infants with simple transposition of the great arteries and intact ventricular septum were operated on from October 1983 to October 1986. The age at operation in 22 infants ranged from 2 to 21 days and in one was 35 days (mean 9.82 +/- 6.86 days). The infants were evaluated with cardiac catheterization at 1 to 27 days of age. Twenty-two infants had balloon atrial septostomy, and 22 received prostaglandin E1 infusion. The left ventricular diastolic wall thickness, assessed by M-mode echocardiograms, varied between 2.8 and 4 mm. There were two hospital deaths in this group of 23 infants (mortality 8.6%), and there were no late deaths. All surviving patients are doing well clinically. One patient had asymptomatic nonsustained ventricular tachycardia necessitating phenytoin. Postoperative echocardiographic assessment performed on 15 patients at 0.93 +/- 0.61 years of age and cardiac catheterization and angiographic studies on seven patients at 1.07 +/- 0.13 years after operation revealed excellent ventricular performance, good semilunar valve function, and mild gradient at the right ventricular outflow with a mean right ventricular pressure of 37.4 +/- 4.1 torr.
authors.affiliation: Division of Cardiovascular-Thoracic Surgery, Children's Memorial Hospital, Chicago, IL 60614.
authors.forename: F S
authors.initials: FS
authors.lastname: Idriss
authors.forename: M N
authors.initials: MN
authors.lastname: Ilbawi
authors.forename: S Y
authors.initials: SY
authors.lastname: DeLeon
authors.forename: C E
authors.initials: CE
authors.lastname: Duffy
authors.forename: A J
authors.initials: AJ
authors.lastname: Muster
authors.forename: C L
authors.initials: CL
authors.lastname: Backer
authors.forename: T E
authors.initials: TE
authors.lastname: Berry
authors.forename: M H
authors.initials: MH
authors.lastname: Paul
mesh_terms: D001011:Aorta / Q000601:surgery; D006328:Cardiac Catheterization; D003331:Coronary Vessels / Q000601:surgery; D004452:Echocardiography; D005500:Follow-Up Studies; D006346:Heart Septum; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008722:Methods; D011651:Pulmonary Artery / Q000601:surgery; D013536:Suture Techniques; D014188:Transposition of Great Vessels / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*