Familial meningioma. Case report with cytogenetic study.
A family is presented of which two members were shown to have an intracranial meningioma. We performed a chromosome study in the affected living individual and several other relatives, with special attention for chromosome 22 anomalies. In neither of them a chromosomal abnormality could be detected. However, in view of the recent cytogenetic findings reported in meningioma, it is suggested that karyotyping should be performed in every family with two or more members affected by meningioma.
Van Landegem
W
W
Department of Neurology, University Hospital, State University Gent, Belgium.
Vakaet
A
A
De Paepe
A
A
Verschraegen-Spae
M R
MR
D000368:Aged; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000235:genetics*; D008579:Meningioma / Q000235:genetics*; D008875:Middle Aged; D010375:Pedigree