Tumours of the renal pelvis and ureter. Observations in 170 patients.
A study was made of 170 patients with renal pelvis or ureteric tumours, 160 of whom underwent surgery between 1948 and 1981. The most important aetiological factor was chronic phenacetin abuse: 21.7% of 83 patients with renal pelvis tumours and 11.4% of those with ureteric tumours gave a history of phenacetin abuse. The latency periods ranged from 24 to 26 years. This is the first report of a relationship between abuse of analgesics and urothelial tumours from the Federal Republic of Germany.
Steffens
J
J
Department of Urology, Free University of Berlin, Charlottenburg Hospital, West Germany.
Nagel
R
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology; D007682:Kidney Pelvis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010212:Papilloma / Q000473:pathology; D010615:Phenacetin / Q000009:adverse effects; D012509:Sarcoma / Q000473:pathology; D019966:Substance-Related Disorders / Q000150:complications; D014516:Ureteral Neoplasms / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000556:secondary
D010615:Phenacetin