title: [Giant lymph nodes in combined autoimmune neutro- and thrombocytopenia].
abstract: A boy aged 15 years is described in whom a combined autoimmune neutro- and thrombocytopenia developed since the age of 11. Cell-membrane bound IgG antibodies were detected on neutrophils and platelets. A therapy with prednisone and/or immunoglobulins showed only a transient normalization of the peripheral blood values. In the course of this disease a lymph node adenopathy occurred showing histologically follicle hyperplasia with multiple plasma cells and relative atrophy of the paracortical T-cell region.
authors.affiliation: Universitäts-Kinderklinik, Freiburg.
authors.forename: H
authors.initials: H
authors.lastname: Schneider
authors.forename: A
authors.initials: A
authors.lastname: Jobke
authors.forename: N
authors.initials: N
authors.lastname: Böhm
mesh_terms: D000380:Agranulocytosis / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000276:immunology* / Q000473:pathology; D005871:Castleman Disease / Q000276:immunology*; D002648:Child; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000032:analysis; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009503:Neutropenia / Q000276:immunology* / Q000473:pathology; D013921:Thrombocytopenia / Q000276:immunology* / Q000473:pathology
chemical_list: D001323:Autoantibodies; D007074:Immunoglobulin G
vernacular_title: Riesenlymphknoten bei kombinierter Autoimmun-Neutro- und Thrombozytopenie.