A study of the effects of four concentrations of D-timolol, 0.25% L-timolol, and placebo on intraocular pressure on patients with raised intraocular pressure.
The intraocular pressure lowering effect in 30 patients with raised intraocular pressure and open angles following a single application in a randomised double-masked fashion of four concentrations of D-timolol (0.25%, 0.5%, 1.0%, and 2.0%), 0.25% L-timolol, and placebo are presented. The percentage reduction in intraocular pressure after four hours following single-drop instillation range from 20% to 25% in the D-timolol group, 32% in the L-timolol group, and only 8% in the placebo group of treated eyes.
Mills
K B
KB
Manchester Royal Eye Hospital.
Jacobs
N J
NJ
Vogel
R
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D009798:Ocular Hypertension / Q000188:drug therapy*; D011897:Random Allocation; D013237:Stereoisomerism; D013999:Timolol / Q000008:administration & dosage* / Q000627:therapeutic use
D013999:Timolol