title: Molecular characterization of ataxia telangiectasia T cell clones. III. Mapping the 14q32.1 distal breakpoint.
abstract: To delimit the 14q32.1 recurrent breakpoint of ataxia telangiectasia clones, we performed an in situ hybridization study with various probes located on the 14q32 band. We thus mapped this breakpoint between the D14S1 and Pi loci. Furthermore, an interstitial duplication including D14S1 and a part of the IgH locus was demonstrated on a t(14;14) clone.
authors.affiliation: INSERM U. 132, Hôpital Necker, Paris, France.
authors.forename: M H
authors.initials: MH
authors.lastname: Stern
authors.forename: F R
authors.initials: FR
authors.lastname: Zhang
authors.forename: G
authors.initials: G
authors.lastname: Thomas
authors.forename: C
authors.initials: C
authors.lastname: Griscelli
authors.forename: A
authors.initials: A
authors.lastname: Aurias
mesh_terms: D001260:Ataxia Telangiectasia / Q000235:genetics*; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002883:Chromosomes, Human, Pair 14; D015342:DNA Probes; D006801:Humans; D007621:Karyotyping; D009693:Nucleic Acid Hybridization; D013601:T-Lymphocytes
chemical_list: D015342:DNA Probes