Sequence analysis of the hemagglutinin of B/Ann Arbor/1/86, an epidemiologically significant variant of influenza B virus.
Influenza B/Ann Arbor/1/86 is representative of antigenic variants responsible for the most important influenza epidemics during the 1985/1986 season. The nucleotide sequence of the hemagglutinin HA1 region and the deduced amino acid sequence are presented. Compared to the previous winter's vaccine strain B/USSR/100/83, B/AA/1/86 possesses 18 amino acid substitutions and 2 amino acid insertions, 50% of which are distributed within the vicinity of the reported single immunodominant antigenic site.
Bootman
J S
JS
National Institute for Biological Standards and Control, South Mimms, Hertfordshire, United Kingdom.
Robertson
J S
JS
D000595:Amino Acid Sequence; D001483:Base Sequence; D005075:Biological Evolution; D006389:Hemagglutinins, Viral / Q000235:genetics*; D009981:Influenza B virus / Q000235:genetics*; D008969:Molecular Sequence Data
D006389:Hemagglutinins, Viral