Inhibitors of N-nitroso compounds-induced mutagenicity.
N-Nitroso compounds are environmental mutagens that are present in the air, water, soil etc. or can be formed by nitrosation of various nitrosatable compounds. The present paper gives a survey of inhibitors of N-nitroso compounds-induced mutagenicity. Inhibitors covered include: thiols, metals, vitamins, phenolic acids, complex mixtures of plant, animal and human origin, organic solvents, inhibitors of mixed-function oxidases etc. Data on inhibitors that prevent the formation of N-nitroso compounds are not covered in this review.
Gichner
T
T
Institute of Experimental Botany, Czechoslovak Academy of Sciences, Praha 5.
Velemínský
J
J
D010129:4-Aminobenzoic Acid / Q000494:pharmacology; D000693:Anaerobiosis; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001386:Azides / Q000494:pharmacology; D001826:Body Fluids; D005504:Food Analysis; D006801:Humans; D008670:Metals / Q000494:pharmacology; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors; D009152:Mutagenicity Tests; D009603:Nitroso Compounds / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D010636:Phenols / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology; D019810:Sodium Azide; D012997:Solvents / Q000494:pharmacology; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D014020:Tissue Extracts / Q000494:pharmacology; D014815:Vitamins / Q000494:pharmacology
D000975:Antioxidants; D001386:Azides; D008670:Metals; D009603:Nitroso Compounds; D010636:Phenols; D010936:Plant Extracts; D012997:Solvents; D013438:Sulfhydryl Compounds; D014020:Tissue Extracts; D014815:Vitamins; D019810:Sodium Azide; D006899:Mixed Function Oxygenases; D010129:4-Aminobenzoic Acid