title: [Soluble and membrane-bound forms of neutral alpha-glucosidase in human urine in normal conditions and in kidney diseases].
abstract: Soluble and membrane-bound forms of neutral alpha-glucosidase, which are immunologically similar to the corresponding forms of kidney enzymes, were found in urine of healthy persons and of patients with kidney impairments. Membrane-bound enzyme was only slightly active in urine of healthy persons and constituted 3-10% of total urine activity although the ratio of membrane-bound enzyme was simultaneously elevated under pathological conditions. The increased rate of soluble enzyme secretion was responsible for distinct activation of neutral alpha-glucosidase in urine of the patients with kidney impairments.
authors.forename: N A
authors.initials: NA
authors.lastname: Ushakova
authors.forename: T P
authors.initials: TP
authors.lastname: Lavrenova
authors.forename: E V
authors.initials: EV
authors.lastname: Kazlas
authors.forename: N A
authors.initials: NA
authors.lastname: Tomilina
authors.forename: M L
authors.initials: ML
authors.lastname: Zubkin
mesh_terms: D006801:Humans; D007668:Kidney / Q000201:enzymology*; D007674:Kidney Diseases / Q000175:diagnosis / Q000201:enzymology* / Q000652:urine; D008871:Microvilli / Q000201:enzymology; D017830:Octoxynol; D011092:Polyethylene Glycols; D012016:Reference Values; D012995:Solubility; D000520:alpha-Glucosidases / Q000302:isolation & purification / Q000652:urine*
chemical_list: D011092:Polyethylene Glycols; D017830:Octoxynol; D000520:alpha-Glucosidases
vernacular_title: Rastvorimaia i membranno-sviazannaia formy neĭtral'noĭ alpha-gliukozidazy mochi cheloveka v norme i pri zabolevaniiakh pochek.