title: PTFE versus human umbilical vein in above knee femoro-popliteal bypass. Early results of a randomized clinical trial.
abstract: The results of a prospective randomized clinical trial comparing PTFE and HUV grafts in above knee femoro-popliteal reconstruction are presented. A total of 93 limbs were randomized, three patients died in the early postoperative period, leaving 90 (45 PTFE and 45 HUV bypasses) to be analysed. During 18 months of follow-up only 3 HUV grafts occluded in contrast to 15 occluded PTFE grafts. After one year patency rates for HUV were 90% versus 67% for PTFE grafts, after 18 months 86% and 63% respectively. From one year postoperatively onwards these results are statistically and significantly different. When an above knee femoro-popliteal reconstruction is performed and autologous vein is not available or purposely not used, HUV gives better results than PTFE and is the graft of choice.
authors.affiliation: Department of Surgery, St. Elisabeth Hospital, Tilburg, The Netherlands.
authors.forename: G J
authors.initials: GJ
authors.lastname: Aalders
authors.forename: T J
authors.initials: TJ
authors.lastname: van Vroonhoven
authors.forename: H J
authors.initials: HJ
authors.lastname: Lobach
authors.forename: C C
authors.initials: CC
authors.lastname: Wijffels
mesh_terms: D000714:Anastomosis, Surgical; D001807:Blood Vessel Prosthesis; D002986:Clinical Trials as Topic; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D006801:Humans; D007717:Knee; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011150:Popliteal Artery / Q000601:surgery*; D011446:Prospective Studies; D011897:Random Allocation; D014471:Umbilical Veins / Q000637:transplantation*; D014654:Vascular Patency
chemical_list: D011138:Polytetrafluoroethylene