title: The effects of axotomy on electrophysiological properties of B cells of bullfrog sympathetic ganglia conditioned by a previous lesion.
abstract: In bullfrog sympathetic B cells, axotomy decreases the amplitude and decay time of membrane afterhyperpolarization (AHP) and increases action potential (AP) duration. A second (test) axotomy, 7 days after an initial (conditioning) axotomy, did not amplify these changes. No recovery of AHP amplitude or AP duration occurred by 56 days post-axotomy, but AHP decay time recovered 21 days earlier than after test axotomy alone. Conditioning, previously shown to accelerate regeneration, speeds the return to normal of those membrane properties previously shown to recover after axotomy.
authors.affiliation: Department of Medical Physiology, University of Calgary, Alta, Canada.
authors.forename: M E
authors.initials: ME
authors.lastname: Kelly
authors.forename: M A
authors.initials: MA
authors.lastname: Bisby
authors.forename: K
authors.initials: K
authors.lastname: Lukowiak
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology*; D004594:Electrophysiology; D005725:Ganglia, Autonomic / Q000166:cytology / Q000502:physiology*; D008564:Membrane Potentials; D011892:Rana catesbeiana; D013997:Time Factors