[Lymphopoietic characteristics in acute hypobaric hypoxia].
10 healthy men were examined, that underwent a 48 hours hypobaric (acute) hypoxia in the climate chamber "Tabaĭ", with conditions corresponding to those at an altitude of 4,000 m. The "ascent" and "descent" were performed correspondingly within 30 minutes. Increased share of dying lymphocytes and frequency of chromosomal aberrations in these were found in addition to an elevated activity of nucleolar organizers and to changed morphological patterns of argentophilic nucleoli. T- and B-lymphocyte contents remained unchanged. The role of the lymphopoietic alterations in autoimmune complications and of hemopoietic disorders in the mountains is discussed.
Filev
L V
LV
Petrova
T N
TN
Bykhovets
I V
IV
Enokhin
S F
SF
Kotsiubinskiĭ
N N
NN
D000208:Acute Disease; D001273:Atmosphere Exposure Chambers; D001402:B-Lymphocytes / Q000276:immunology; D002869:Chromosome Aberrations; D006410:Hematopoiesis; D006801:Humans; D000860:Hypoxia / Q000097:blood* / Q000276:immunology; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000166:cytology*; D008297:Male; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology
Osobennosti limfopoéza pri ostroĭ gipobaricheskoĭ gipoksii.