[Congenital poikiloderma with verrucous hyperkeratosis. An unusual form of Thomson's syndrome?].
A 50 year old male patient suffered from poikilodermatous skin since his 14th year of life. During the past 5 years hyperkeratotic plaques and squamous cell carcinomas developed, leading to metastases into lymph nodes and the lung and fatal outcome. To our knowledge, up to now 6 cases of congenital poikiloderma (Thomson-syndrome, Rothmund-Thomson-syndrome) in conjunction with verrucous hyperkeratosis and squamous cell carcinoma have been reported in the literature.
Schrallhammer
K
K
Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München.
Burg
G
G
Stolz
W
W
Braun-Falco
O
O
D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D007642:Keratosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011038:Rothmund-Thomson Syndrome / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology*; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology / Q000601:surgery; D016038:Skin Transplantation; D013577:Syndrome
Kongenitale Poikilodermie mit warzigen Hyperkeratosen. Eine Sonderform des Thomson-Syndroms?