title: Systemic lupus erythematosus presenting as a bullous eruption in a child.
abstract: An 8-year-old girl presented with a generalized bullous eruption clinically resembling bullous pemphigoid or chronic bullous disease of childhood. Further study revealed immunopathologic findings seen in patients with epidermolysis bullosa acquisita or bullous systemic lupus erythematosus (SLE). Although she did not fulfill the American Rheumatism Association (Atlanta) criteria for SLE at her presentation, one year later she went on to do so. As well as being the youngest patient reported with bullous SLE, our patient is noteworthy because the bullous eruption was the initial manifestation of her SLE. Bullous SLE should be considered in the differential diagnosis of children presenting with generalized bullous eruptions.
authors.affiliation: Department of Dermatology, Baylor College of Medicine, Houston.
authors.forename: A H
authors.initials: AH
authors.lastname: Kettler
authors.forename: S F
authors.initials: SF
authors.lastname: Bean
authors.forename: J O
authors.initials: JO
authors.lastname: Duffy
authors.forename: W R
authors.initials: WR
authors.lastname: Gammon
mesh_terms: D000367:Age Factors; D002648:Child; D003622:Dapsone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000473:pathology*; D013427:Sulfapyridine / Q000627:therapeutic use
chemical_list: D003622:Dapsone; D011241:Prednisone; D013427:Sulfapyridine