title: Subdural haematoma associated with long term oral anticoagulation.
abstract: Twenty-two patients with subdural haematomas associated with long term oral anticoagulation have been reviewed. Clinical presentation was similar to other subdural haematomas, but patients were generally older and the clinical course was more rapid. The incidence of over-anticoagulation was 23% and there was no correlation between anticoagulant status and the extent of bleeding or prognosis. Mortality was 27%, a residual neurological deficit was present in 14% and 59% made a complete recovery. The results suggest that morbidity and mortality could be reduced by early diagnosis and treatment and any patient on oral anticoagulant therapy who develops a headache or confusion should have urgent neurological investigation, including a CT scan. The indications for long term anticoagulation, particularly in the elderly, should be critically reassessed.
authors.affiliation: Department of Neurosurgery, Royal Victoria Hospital, Belfast, United Kingdom.
authors.forename: T
authors.initials: T
authors.lastname: Diamond
authors.forename: W J
authors.initials: WJ
authors.lastname: Gray
authors.forename: C P
authors.initials: CP
authors.lastname: Chee
authors.forename: T F
authors.initials: TF
authors.lastname: Fannin
mesh_terms: D000284:Administration, Oral; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006408:Hematoma, Subdural / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants