title: Postrhinoplasty epistaxis. Role of vitamin E?
abstract: Postrhinoplasty epistaxis occurred in two patients, both of whom were found to be ingesting megadoses of vitamin E. The rate of vitamin E consumption in a population of 100 uncomplicated nasal operations during this same period was 16%. A review of the medical literature on vitamin E found recent evidence demonstrating a marked decrease in platelet adhesiveness with megadose ingestion of vitamin E. It is concluded that this should be avoided in the perioperative period.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Southern California School of Medicine, Los Angeles.
authors.forename: M M
authors.initials: MM
authors.lastname: Churukian
authors.forename: J
authors.initials: J
authors.lastname: Zemplenyi
authors.forename: M
authors.initials: M
authors.lastname: Steiner
authors.forename: F M
authors.initials: FM
authors.lastname: Kamer
authors.forename: A
authors.initials: A
authors.lastname: Cohen
mesh_terms: D000328:Adult; D004844:Epistaxis / Q000209:etiology*; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D008297:Male; D010973:Platelet Adhesiveness / Q000187:drug effects; D011184:Postoperative Period; D012225:Rhinoplasty / Q000009:adverse effects*; D014810:Vitamin E / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D014810:Vitamin E