Role of active oxygen in paraquat and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) cytotoxicity.
Sandy
M S
MS
Department of Biomedical and Environmental Health Sciences, School of Public Health, University of California, Berkeley 94720.
Di Monte
D
D
Cohen
P
P
Smith
M T
MT
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002330:Carmustine / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003676:Deferoxamine / Q000494:pharmacology*; D005609:Free Radicals; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D010269:Paraquat / Q000633:toxicity*; D010655:Phenylenediamines / Q000494:pharmacology*; D011725:Pyridines / Q000633:toxicity*; D051381:Rats; D012016:Reference Values; D014810:Vitamin E / Q000378:metabolism
D000975:Antioxidants; D005609:Free Radicals; D010655:Phenylenediamines; D011725:Pyridines; D014810:Vitamin E; D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; C004845:N,N'-diphenyl-4-phenylenediamine; D003676:Deferoxamine; D010269:Paraquat; D002330:Carmustine