title: [Vascular abnormalities of the umbilical cord--incidence, significance and possibility for prenatal ultrasonic detection].
abstract: Vascular anomalies of the umbilical cord are amongst the most frequent congenital malformations, their incidence being 0.2% to 1.4%. As a result of the latter the risk of occurrence of other malformations and chromosomal anomalies is markedly elevated. Between January 1977 and July 1987 a total of 78 cases (0.51%) of umbilical cord vascular anomalies were recorded at the Department of Gynaecology of the University of Heidelberg. Malformations occurred in 37% of the foetuses involved. 28% showed retarded growth and 9% had an abnormal set of chromosomes. Anomalies of the urinary tract and malformations of the thoracic organs were very frequent. Total mortality after the 28th pregnancy was about 14%. Currently available high-resolution real-time ultrasound equipment can show up even prenatally pathological variations of the umbilical vascular pedicle (e.g. a single umbilical artery). Because of the manifold risk involved, routine ultrasound control is recommended. If this anomaly is diagnosed, the pregnancy should be classified and treated immediately as a high-risk pregnancy.
authors.affiliation: Abt. Allg. Geburtshilfe und Gynäkologie mit Poliklinik, Universitäts-Frauenklinik Heidelberg.
authors.forename: J
authors.initials: J
authors.lastname: Gnirs
authors.forename: J
authors.initials: J
authors.lastname: Hendrik
authors.forename: D
authors.initials: D
authors.lastname: Heberling
authors.forename: W
authors.initials: W
authors.lastname: Schmidt
mesh_terms: D000015:Abnormalities, Multiple / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000002:abnormalities* / Q000473:pathology
vernacular_title: Gefässanomalien der Nabelschnur--Inzidenz, Bedeutung und Möglichkeit der pränatalen ultrasonographischen Erfassung.