title: Mechanism of inhibition of prostacyclin synthesis by cyclosporine in cultured human umbilical vein endothelial cells.
authors.affiliation: Department of Renal Medicine, St. Philip's Hospital, London, England.
authors.forename: Z
authors.initials: Z
authors.lastname: Brown
authors.forename: G H
authors.initials: GH
authors.lastname: Neild
authors.forename: G P
authors.initials: GP
authors.lastname: Lewis
mesh_terms: D003524:Cyclosporins / Q000494:pharmacology*; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System; D004730:Endothelium, Vascular / Q000187:drug effects*; D011464:Epoprostenol / Q000096:biosynthesis*; D006801:Humans; D066298:In Vitro Techniques; D007213:Indomethacin / Q000494:pharmacology; D019746:Intramolecular Oxidoreductases; D007535:Isomerases / Q000037:antagonists & inhibitors; D014176:Protein Biosynthesis; D013917:Thrombin / Q000494:pharmacology
chemical_list: D003524:Cyclosporins; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System; D011464:Epoprostenol; D013917:Thrombin; D007535:Isomerases; D019746:Intramolecular Oxidoreductases; C022461:prostacyclin synthetase; D007213:Indomethacin