There are no alternatives to double-blind, controlled trials.
Noseworthy
J H
JH
Department of Clinical Neurological Sciences, University of Western Ontario, London, Canada.
D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005500:Follow-Up Studies; D006801:Humans; D009103:Multiple Sclerosis / Q000628:therapy*; D012107:Research Design