title: Agnathia, holoprosencephaly, and situs inversus: report of a case.
abstract: We present the first documented case of agnathia-holoprosencephaly (an uncommon form of craniofacial anomaly) associated with situs inversus. This case may represent the concordance of multiple field complex anomalies, but the possibility of a major midline malformation (situs inversus) caused by a timed insult (environmental or genetic) which affects multiple structures and occurs concurrently with a major field defect during early embryogenesis cannot be excluded.
authors.affiliation: Department of Pathology, University of Oklahoma College of Medicine, Oklahoma City 73190.
authors.forename: R W
authors.initials: RW
authors.lastname: Leech
authors.forename: L S
authors.initials: LS
authors.lastname: Bowlby
authors.forename: R A
authors.initials: RA
authors.lastname: Brumback
authors.forename: G B
authors.initials: GB
authors.lastname: Schaefer
mesh_terms: D000015:Abnormalities, Multiple; D005147:Facial Bones / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012886:Skull / Q000002:abnormalities*