Role of dose, schedule and route of administration of 5-formyltetra-hydrofolate: preclinical and clinical investigations.
Rustum
Y M
YM
Grace Cancer Drug Center and Experimental Therapeutics, Roswell Park Memorial Institute, Buffalo, NY 14263.
Liu
L
L
Zhang
Z
Z
D000284:Administration, Oral; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015179:Colorectal Neoplasms / Q000097:blood / Q000188:drug therapy*; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use; D006207:Half-Life; D006801:Humans; D007262:Infusions, Intravenous; D002955:Leucovorin / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D007942:Leukemia, Experimental / Q000188:drug therapy; D008175:Lung Neoplasms / Q000097:blood / Q000188:drug therapy*; D051379:Mice; D008811:Mice, Inbred DBA; D009374:Neoplasms, Experimental / Q000188:drug therapy
D002955:Leucovorin; D005472:Fluorouracil