Effect of recent antibacterial agents against bacteria causing diarrhoea.
The susceptibility of 424 bacterial isolates causing diarrhoea were tested by agar dilution technique on Mueller-Hinton Agar against amoxicillin, ampicillin, ceftriaxone, chloramphenicol, co-trimoxazole, ciprofloxacin, doxycycline, norfloxacin and ofloxacin. The bacterial species included were Aeromonas hydrophila, Edwardsiella tarda, Pleisomonas shigelloides, Salmonella spp., Shigella spp., Vibrio cholerae and Vibrio parahaemolyticus. The most active compounds were the fluorinated 4-quinolones studied, that is, ciprofloxacin, norfloxacin and ofloxacin, and ceftriaxone. The other antibacterial agents were considerably less active; a substantial portion of tested isolates were resistant to them.
Bergan
T
T
Department of Microbiology, Faculty of Medicine, National University of Singapore.
Lolekha
S
S
Cheong
M K
MK
Poh
C L
CL
Doencham
S
S
Charoenpipop
D
D
D042462:4-Quinolones; D000667:Ampicillin / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D002443:Ceftriaxone / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003967:Diarrhea / Q000382:microbiology*; D004318:Doxycycline / Q000494:pharmacology; D004338:Drug Combinations / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D013420:Sulfamethoxazole / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D042462:4-Quinolones; D000890:Anti-Infective Agents; D004338:Drug Combinations; D002701:Chloramphenicol; D002443:Ceftriaxone; D000667:Ampicillin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole; D004318:Doxycycline