title: [Alternating hemiplegia in childhood. Clinical report and single photon emission computed tomography study].
abstract: From 6 months of age on this girl experienced frequent episodes of hemiplegia involving both sides of the body and lasting up to 8 days. The attacks were often precipitated by tonic deviation of the head and/or the eyes to one side and nystagmus. At this stage the girl used to cry. Squinting, tonic stiffening of body and extremities, and dystonic posturing also occurred. Autonomic dysfunctions such as paleness of the skin, sweating, respiratory embarrassment, tachycardia, and mydriasis were associated features of the attacks. Motor and mental development of the girl is delayed. Improvement concerning severity, duration and frequency of the attacks has been achieved by permanent treatment with flunarizine in combination with acetazolamide and acetylsalicylic acid. If the child falls asleep immediately after rectal application of chloral hydrate at the onset of an attack there is no hemiplegia after awakening.
authors.affiliation: Rittberg-Kinderklinik Berlin.
authors.forename: H
authors.initials: H
authors.lastname: Siemes
authors.forename: P
authors.initials: P
authors.lastname: Casaer
mesh_terms: D000086:Acetazolamide / Q000008:administration & dosage; D001241:Aspirin / Q000008:administration & dosage; D002545:Brain Ischemia / Q000000981:diagnostic imaging; D002540:Cerebral Cortex / Q000098:blood supply; D002675:Child, Preschool; D002697:Chloral Hydrate / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005444:Flunarizine / Q000008:administration & dosage; D006429:Hemiplegia / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D008881:Migraine Disorders / Q000000981:diagnostic imaging* / Q000188:drug therapy; D014055:Tomography, Emission-Computed
chemical_list: D002697:Chloral Hydrate; D000086:Acetazolamide; D001241:Aspirin; D005444:Flunarizine
vernacular_title: Alternierende Hemiplegie des Kindesalters. Klinischer Bericht und SPECT-Studie.