[Adsorption of insulin to the Perfusor systems].
Using radioimmunoassay determination we examined the recovery rate of 100 units of regular insulin that had been added to 50 ml. of a carrier solution in a plastic Perfusor syringe. We measured the recovery rate with sodium chloride 0.9% as carrier and after adding albumin (10 g./l.) and gelatine (6 g./l. resp. 12 g./l.). An initial insulin loss of 26% (with albumin) to 37% (with gelatine) was followed by only a small loss (less than 9%) during the next 24 hours. We conclude from our results that it is unnecessary to add substances with high molecular weight in order to reduce insulin adsorption to Perfusor systems.
Böhrer
H
H
Klinik für Anästhesiologie der Universität Heidelberg.
Krier
C
C
Fleischer
F
F
Jürs
G
G
Schneider
C
C
D000327:Adsorption; D005780:Gelatin; D006801:Humans; D007328:Insulin; D007332:Insulin Infusion Systems; D061389:Insulin, Regular, Pork; D011863:Radioimmunoassay; D012709:Serum Albumin; D013594:Syringes
D007328:Insulin; D061389:Insulin, Regular, Pork; D012709:Serum Albumin; D005780:Gelatin; C000006:insulin, neutral
Adsorption von Insulin an Perfusor-Systeme.