title: Early immunization of calves with an inactivated vaccine against trichophytosis.
abstract: The investigations demonstrated that the inactivated vaccine against trichophytosis, elaborated by the authors, induced immune response in calves, aged 5-8 days. The state of immunity was assessed in vitro by the leukocyte migration inhibition test, and in vivo by the allergic test and the challenge test. In all vaccinated calves (10 animals) there occurred delayed hypersensitivity and in six cases also a significant leukocyte migration inhibition. Vaccinated animals exposed to challenge were to a large extent resistant to experimental infection with the virulent strain of T. verrucosum.
authors.affiliation: Department of Microbiology, Institute of Infectious and Invasive Diseases, Agricultural Academy, Lublin.
authors.forename: K
authors.initials: K
authors.lastname: Wawrzkiewicz
authors.forename: J
authors.initials: J
authors.lastname: Wawrzkiewicz
mesh_terms: D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D002417:Cattle / Q000276:immunology*; D002418:Cattle Diseases / Q000276:immunology / Q000517:prevention & control*; D005657:Fungal Vaccines / Q000008:administration & dosage* / Q000276:immunology; D011044:Poland; D013997:Time Factors; D014005:Tinea / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D014249:Trichophyton / Q000276:immunology*; D015164:Vaccines, Inactivated / Q000008:administration & dosage / Q000276:immunology
chemical_list: D005657:Fungal Vaccines; D015164:Vaccines, Inactivated