title: [Clonogenic cultivation of bone marrow fibroblast precursors in human myeloproliferative diseases].
abstract: Techniques of clonogenic cultivation with the application of xenogenous feeder (rabbit irradiated bone marrow) were used to study a number of bone marrow colony-forming cells (CFU-F) in 70 patients. A significant increase of CFU-F is observed in chronic myelocytic leukemia and in hepatosplenomegalies of non-leukemic origin CFU-F decreases considerably in the cases of myelofibrosis. Trypsinisation of the bone marrow taken from the cases of myelofibrosis results in a sharp CFU-F increase.
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Kolosova
authors.forename: E B
authors.initials: EB
authors.lastname: Vladimirskaia
authors.forename: L G
authors.initials: LG
authors.lastname: Kovaleva
mesh_terms: D001853:Bone Marrow / Q000473:pathology*; D002999:Clone Cells / Q000473:pathology; D003114:Colony-Forming Units Assay; D003584:Cytological Techniques; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D009196:Myeloproliferative Disorders / Q000473:pathology*; D013234:Stem Cells / Q000473:pathology*
vernacular_title: Klonogennoe kul'tivirovanie predshestvennikov kostno-mozgovykh fibroblastov pri mieloproliferativnykh zabolevaniiakh cheloveka.