Antiblastic chemotherapy and reproductive life.
In the present work the Authors, on the basis of most recent literature have tried to show some general outline with regard to the effects of antiblastic chemotherapy on the "ovarian function" in patients of pre-puberal and fertile age, understood that this would mean complex interference between endocrine and gametogenic; they have besides faced the problem of the gestational capacity of such patients. Notable difficulties have derived from the fact that the data in Literature are often non-comparable among themselves and, at times, discordant. However, although they have been unable to reach unequivocal conclusions, they hope to have made some practical contribution to those who, ever more often, find themselves having to face such problems.
Romagnolo
C
C
Institute of the Gynecologic, University of Padua, Italy.
Marchesoni
D
D
Maggino
T
T
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology; D000022:Abortion, Spontaneous / Q000139:chemically induced / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000187:drug effects; D011247:Pregnancy; D011627:Puberty / Q000187:drug effects; D012098:Reproduction / Q000187:drug effects*
D000970:Antineoplastic Agents