title: The surgical treatment of aortic regurgitation secondary to aortitis.
abstract: We describe the operative and perioperative management of 11 patients with aortic regurgitation due to aortitis. All patients required aortic valve replacement because of severely uncoapted cusps secondary to dilatation of the ascending aorta. The right coronary ostium was narrowed in 5 patients and consequently necessitated a smaller coronary tip for the administration of cardioplegic solution. To implant the prosthetic valve, pledgeted 2-0 Tevdek sutures were placed through the aortic valve annulus either from the ventricular side or from outside the aortic wall. Steroids were administered to 4 patients preoperatively and 8 patients postoperatively. Postoperative dehiscence of the prosthesis was seen in 1 of the 3 patients not given any steriods. We conclude that it is important to arrest the inflammatory reaction before operation and if the aortic valve must be replaced, to reinforce the implanted prosthesis with pledgeted sutures. Also, we suggest the possible importance of steroid therapy.
authors.affiliation: Second Department of Surgery, Kurume University Hospital, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Isomura
authors.forename: K
authors.initials: K
authors.lastname: Hisatomi
authors.forename: I
authors.initials: I
authors.lastname: Yanagi
authors.forename: S
authors.initials: S
authors.lastname: Shimada
authors.forename: K
authors.initials: K
authors.lastname: Uraguchi
authors.forename: S
authors.initials: S
authors.lastname: Aoyagi
authors.forename: K
authors.initials: K
authors.lastname: Kosuga
authors.forename: K
authors.initials: K
authors.lastname: Ohishi
mesh_terms: D000328:Adult; D001021:Aortic Valve; D001022:Aortic Valve Insufficiency / Q000209:etiology / Q000601:surgery*; D001025:Aortitis / Q000150:complications*; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D013536:Suture Techniques
chemical_list: D011241:Prednisone