title: The clinical use and measurement of theophylline.
abstract: This report reviews the clinical use, metabolism and toxicity of theophylline (Section 1). Current chromatographic and immunoassay methods for theophylline measurement are discussed and practical methods using high-performance liquid chromatography are described (Section 2). Results from the UK National scheme for theophylline quality control and from an experiment to investigate the degree of interference by 1,7-dimethylxanthine in routine assays for theophylline are discussed in Section 3.
authors.affiliation: Department of Chemical Pathology, General Hospital, Southampton, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Rowe
authors.forename: I D
authors.initials: ID
authors.lastname: Watson
authors.forename: J
authors.initials: J
authors.lastname: Williams
authors.forename: D J
authors.initials: DJ
authors.lastname: Berry
mesh_terms: D006801:Humans; D011786:Quality Control; D013806:Theophylline / Q000493:pharmacokinetics* / Q000627:therapeutic use
chemical_list: D013806:Theophylline