title: Localization of the novel neuropolypeptide h3 in subsets of tissues from different species.
abstract: Recently we reported the isolation and partial biochemical characterization of a novel polypeptide, h3, from the human brain and liver. Thin-layer isoelectric focusing showed that the polypeptide was ubiquitously distributed throughout the human brain. Immunophosphatase transfer electrophoresis showed that this protein was localized in several mammalian species and different tissues. In addition, h3 or h3-like protein was demonstrated in subsets of tissues from one avian species. Protein h3 was present in epithelial and muscular tissue, as well as in nervous tissue; however, for all species investigated, it was most abundant in CNS and muscle.
authors.affiliation: Laboratorium voor Fysiopathologie van het Zenuwstelsel-Farmakologie, Vrije Universiteit Brussel, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Bollengier
authors.forename: A
authors.initials: A
authors.lastname: Mahler
mesh_terms: D000727:Androgen-Binding Protein; D000818:Animals; D001923:Brain Chemistry; D002417:Cattle; D002645:Chickens; D004064:Digestive System / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007124:Immunoenzyme Techniques; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D009206:Myocardium / Q000032:analysis; D009419:Nerve Tissue Proteins / Q000032:analysis*; D049488:Phosphatidylethanolamine Binding Protein; D060789:Prostatein; D011506:Proteins / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D060765:Secretoglobins; D012756:Sheep; D013045:Species Specificity; D013154:Spleen / Q000032:analysis; D014018:Tissue Distribution; D014598:Uteroglobin; D060788:Mammaglobin B
chemical_list: D000727:Androgen-Binding Protein; D009419:Nerve Tissue Proteins; D049488:Phosphatidylethanolamine Binding Protein; D060789:Prostatein; D011506:Proteins; D060765:Secretoglobins; D014598:Uteroglobin; C511482:PEBP1 protein, human; C511484:Scgb1d2 protein, rat; C511483:Scgb1d4 protein, rat; C556468:Scgb2a1 protein, rat; D060788:Mammaglobin B