title: Large plasmid in Shigella boydii is responsible for epithelial cell penetration.
abstract: A large plasmid in a virulent Shigella boydii 5 strain was transferred to plasmid-cured avirulent strains of S. boydii 5, S. boydii 12, S. sonnei form II, and Escherichia coli K12. The transconjugants acquired the ability to invade tissue culture cells, which indicated that the large plasmid in S. boydii is responsible for epithelial cell invasiveness.
authors.affiliation: Department of Microbiology, Institute of Public Health, Tokyo.
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshida
authors.forename: N
authors.initials: N
authors.lastname: Okamura
mesh_terms: D000818:Animals; D003227:Conjugation, Genetic; D046508:Culture Techniques; D004848:Epithelium / Q000382:microbiology; D004926:Escherichia coli / Q000235:genetics; D010957:Plasmids; D012760:Shigella / Q000235:genetics*; D012761:Shigella boydii / Q000235:genetics* / Q000472:pathogenicity; D014774:Virulence