Human polymorphic APO-LDL investigated by high-resolution two-dimensional electrophoresis.
The APO part of a human polymorphic low density lipoprotein (LDL) was investigated by two-dimensional electrophoresis. Since these allotypic LDL were purified from sera by specific immunochromatography, the data presented here refer to only one molecular species of LDL. The two-dimensional electrophoresis revealed the presence of isoforms which were correlated to the serological phenotype. A hypothesis about APO-LDL gene organization is outlined.
De Benedictis
G
G
Department of Cell Biology, University of Calabria, Arcavacata.
Di Maio
E
E
Rose
G
G
Renis
M
M
Brancati
C
C
Tagarelli
A
A
D001053:Apolipoproteins / Q000235:genetics*; D015180:Electrophoresis, Gel, Two-Dimensional; D015870:Gene Expression; D006801:Humans; D008077:Lipoproteins, LDL / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic; D013789:Thalassemia / Q000097:blood / Q000235:genetics
D001053:Apolipoproteins; D008077:Lipoproteins, LDL; C010681:apolipoprotein LDL, human