title: Chemical and biological properties of indole glucosinolates (glucobrassicins): a review.
abstract: Glucosinolates are a group of secondary products commonly, but not exclusively, found in plants of the family Cruciferae. They give rise, upon enzymic hydrolysis, to a range of volatile, pungent and physiologically active compounds. Recently, particular attention has been focused upon those that are trytophan-derived--the indole glucosinolates (glucobrassicins). When chemically or enzymically hydrolysed these compounds give rise to a range of involatile indole compounds which have been implicated in the anti-carcinogenic and mixed-function-oxidase stimulatory activities of brassica vegetables. This review details the chemical and physiological properties of indole glucosinolates and their products and suggests possible areas for future research.
authors.affiliation: Department of Toxicology, Rayne Institute, University College London.
authors.forename: R
authors.initials: R
authors.lastname: McDanell
authors.forename: A E
authors.initials: AE
authors.lastname: McLean
authors.forename: A B
authors.initials: AB
authors.lastname: Hanley
authors.forename: R K
authors.initials: RK
authors.lastname: Heaney
authors.forename: G R
authors.initials: GR
authors.lastname: Fenwick
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005961:Glucosinolates / Q000032:analysis / Q000378:metabolism / Q000494:pharmacology; D006868:Hydrolysis; D007211:Indoles; D010084:Oxidation-Reduction; D004364:Pharmaceutical Preparations / Q000378:metabolism; D051381:Rats; D013865:Thioglycosides / Q000032:analysis / Q000378:metabolism / Q000494:pharmacology
chemical_list: D005961:Glucosinolates; D007211:Indoles; D004364:Pharmaceutical Preparations; D013865:Thioglycosides; C048308:glucobrassicin