title: Validation of a quality of life questionnaire for use in clinical trials for treatment of patients with inoperable lung cancer.
abstract: In order to assess the quality of life of patients with inoperable lung cancer, a questionnaire for patient self-administration with 29 variables was designed including the following subjects: psychosocial well-being, medical side-effects, activities of daily living and physical performance. The questionnaire was validated by using a semistructured interview. Thirty-one patients treated for inoperable lung cancer with either radiotherapy (42%), chemotherapy (42%) or a combination of these two treatment modalities (16%) were included in the study. The multitrait-multimethod matrix (MTMM) was used in the analysis of the construct validity. The present validation study showed a high degree of validity for the majority of the items studied. Some of the items showed a low degree of validity, and are subject to future analysis in large scale studies.
authors.affiliation: Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo, Norway.
authors.forename: S
authors.initials: S
authors.lastname: Kaasa
authors.forename: A
authors.initials: A
authors.lastname: Mastekaasa
authors.forename: I
authors.initials: I
authors.lastname: Stokke
authors.forename: S
authors.initials: S
authors.lastname: Naess
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000523:psychology / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D011795:Surveys and Questionnaires