First case of subcutaneous zygomycosis caused by Saksenaea vasiformis in India.
The first case of subcutaneous zygomycotic infection caused by Saksenaea vasiformis in a rice mill worker from India is described. The infection, confined to the man's left foot, showed multiple draining sinuses, inflammation, and intermittent low-grade fever following a crushing injury when a log fell on his foot. Histopathologic examination of two biopsy specimens, taken at 3-wk intervals, revealed the presence of broad, sparsely septate, branched, hyaline hyphae characteristic of a zygomycete. When they were grown on a nutritionally deficient medium, two cultures isolated from the biopsied tissues formed numerous, vase-shaped sporangia typical of S. vasiformis. Necrosis of the affected area led to amputation of the fore part of the foot. A split thickness graft was well accepted, and treatment with potassium iodide, following the graft, cured the infection.
Padhye
A A
AA
Division of Mycotic Diseases, Centers for Disease Control, Atlanta, GA 30333.
Koshi
G
G
Anandi
V
V
Ponniah
J
J
Sitaram
V
V
Jacob
M
M
Mathai
R
R
Ajello
L
L
Chandler
F W
FW
D000328:Adult; D000671:Amputation, Surgical; D005533:Foot Dermatoses / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007194:India; D008297:Male; D009091:Mucormycosis / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D011193:Potassium Iodide / Q000009:adverse effects / Q000627:therapeutic use
D011193:Potassium Iodide