[Immunohistochemical study of alpha-1-antichymotrypsin and GFAP in glioma].
GFAP is a specific antigen of glial element, but Alpha-1-antichymotrypsin has not been reported in the literature Alpha-1-antichymotrypsin was guided by GFAP using PAP method to the astrocytes of 137 gliomas. 120 (87%) gliomas were positive for Alpha-1-antichymotrypsin. Of these 120 gliomas, 86 (72%) gave diffuse distribution, 17 (14%) gave focal distribution, and 17 (14%) gave scattered distributions. Alpha-1-antichymotrypsin in glioma tissue may be an important tumor marker for diagnosis.
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Department of Pathology, Fourth Military Medical College, Xian.
D001254:Astrocytoma / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D001932:Brain Neoplasms / Q000032:analysis*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis*; D005910:Glioma / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D000514:alpha 1-Antichymotrypsin / Q000032:analysis*
D014408:Biomarkers, Tumor; D005904:Glial Fibrillary Acidic Protein; D000514:alpha 1-Antichymotrypsin