title: Sublingual nifedipine in acute severe hypertension.
abstract: Sublingual nifedipine was used for the treatment of acute severe hypertension in 12 children with renal disease. An average dose of 0.24 mg/kg was safe and proved effective on most occasions within 30 minutes with a median duration of action of three hours. There were no major adverse effects.
authors.affiliation: Department of Paediatrics and Child Health, St James's University Hospital, Leeds.
authors.forename: J H
authors.initials: JH
authors.lastname: Evans
authors.forename: N J
authors.initials: NJ
authors.lastname: Shaw
authors.forename: J T
authors.initials: JT
authors.lastname: Brocklebank
mesh_terms: D000208:Acute Disease; D000286:Administration, Sublingual; D000293:Adolescent; D002648:Child; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D009543:Nifedipine / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D009543:Nifedipine