Colon: relationship between epithelial transport and motility.
Although our knowledge of colonic function is still incomplete, the available data support the concept that for most of the time colonic motor activity is adapted to promote absorption and bacterial metabolism. The possibility that this mode of activity may be enhanced and promoted by the products of fermentation is intriguing and needs to be established. Substances that irritate or stimulate the colon, such as unabsorbed fat, bile acids, bacterial enterotoxins and laxatives and excessive delivery of fluid from the small intestine, flush out colonic contents by causing secretion and colonic propulsion.
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Sub-Department of Human Gastrointestinal Physiology and Nutrition, Royal Hallamshire Hospital, Sheffield, UK.
D001693:Biological Transport, Active; D003106:Colon / Q000502:physiology*; D004848:Epithelium / Q000502:physiology; D005769:Gastrointestinal Motility; D006801:Humans; D007408:Intestinal Absorption