title: Subclavian artery occlusion after radiotherapy for carcinoma of the breast.
abstract: Disturbance of the arterial circulation in the ipsilateral upper limb following mastectomy is a rare sequel attributed to adjuvant radiotherapy. A review of the literature revealed 20 such cases, and two more are presented. Different mechanisms of injury leading to arterial occlusion have been proposed. This is a late complication with a considerable time lag between irradiation and onset of symptoms. The symptoms vary in type and severity, but are consistent with peripheral occlusive arterial disease. To alleviate symptoms and prevent limb loss, reconstructive vascular surgery is advocated, and was successfully performed in one of our patients.
authors.affiliation: Department of Surgery B, Rambam Medical Center, Haifa, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Hashmonai
authors.forename: A
authors.initials: A
authors.lastname: Elami
authors.forename: A
authors.initials: A
authors.lastname: Kuten
authors.forename: C
authors.initials: C
authors.lastname: Lichtig
authors.forename: S
authors.initials: S
authors.lastname: Torem
mesh_terms: D000368:Aged; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D001161:Arteriosclerosis / Q000175:diagnosis; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D008408:Mastectomy; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D013348:Subclavian Artery / Q000473:pathology / Q000528:radiation effects*