Phospholipid flippases.
Protein mediated phospholipid translocation through membranes has been observed in rat liver endoplasmic reticulum and in the plasma membrane of erythrocytes as well as in a few other cell membranes. Lipid translocation in plasma membranes is ATP dependent and selectively accumulates aminophospholipids on the inner monolayers.
Devaux
P F
PF
Institut de Biologie Physico-Chimique, Paris, France.
D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D001692:Biological Transport; D002352:Carrier Proteins / Q000097:blood / Q000502:physiology*; D002462:Cell Membrane / Q000201:enzymology*; D004910:Erythrocyte Membrane / Q000378:metabolism; D005057:Eukaryotic Cells / Q000201:enzymology; D006801:Humans; D008565:Membrane Proteins; D049294:Phospholipid Transfer Proteins; D010743:Phospholipids / Q000378:metabolism*; D011387:Prokaryotic Cells / Q000201:enzymology
D002352:Carrier Proteins; D008565:Membrane Proteins; D049294:Phospholipid Transfer Proteins; D010743:Phospholipids; D000255:Adenosine Triphosphate