Fetal cystic hygroma: prenatal diagnosis and management.
Seventeen cases of fetal cystic hygroma detected during ultrasound examination are reported. In nine instances, associated abnormalities were recognized, such as fetal hydrops and a two-vessel cord. All diagnoses were confirmed at autopsy. Karyotyping revealed normal findings in six cases, Turner's syndrome in eight cases, and Edwards' syndrome in one case; culture failure occurred in the remaining two cases. An ultrasound diagnosis of cystic hygroma should be followed by a careful search for other anomalies and by fetal karyotyping. Afterward, genetic counseling is indicated.
Pijpers
L
L
Department of Obstetrics and Gynecology, Erasmus University Rotterdam, The Netherlands.
Reuss
A
A
Stewart
P A
PA
Wladimiroff
J W
JW
Sachs
E S
ES
D003560:Cysts / Q000175:diagnosis / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000628:therapy; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007621:Karyotyping; D008202:Lymphangioma / Q000175:diagnosis / Q000628:therapy; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011379:Prognosis; D014463:Ultrasonography