Effects of pregnancy and fasting on muscle glucose utilization in the rabbit.
The effects of fasting on maternal glucose metabolism were investigated in nonpregnant and 29-day pregnant conscious rabbits. Pregnancy decreased the glucose metabolic index by 60% in maternal red postural muscles. Fasting induced similar modifications in nonpregnant rabbits and exaggerated the changes observed in fed pregnant animals. These data suggest that the decreased glucose utilization by maternal red muscles observed during pregnancy and fasting is related to the increase in circulating fat-derived substrates, because the fall in plasma insulin concentration is a specific adaptation to fasting.
Hauguel
S
S
Centre de Recherche sur la Nutrition du CNRS, Meudon, France.
Leturque
A
A
Gilbert
M
M
Girard
J
J
D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D005215:Fasting; D005260:Female; D007328:Insulin / Q000097:blood; D009132:Muscles / Q000378:metabolism*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000378:metabolism*; D011817:Rabbits
D001786:Blood Glucose; D007328:Insulin