Thrombocytopenia and drugs.
Thrombocytopenia is a relatively common side effect of drug therapy. The pathogenetic mechanisms of drug-induced thrombocytopenia are varied and sometimes poorly understood. Immunologic and other cytotoxic effects may result in decreased production and/or increased destruction of platelets. The pathogenesis of drug-induced thrombocytopenia is reviewed. Diagnosis and treatment are also discussed.
Handagama
P
P
Department of Pathology, University of California School of Medicine, San Francisco.
Feldman
B F
BF
D000818:Animals; D001792:Blood Platelets / Q000187:drug effects*; D013921:Thrombocytopenia / Q000139:chemically induced / Q000628:therapy / Q000662:veterinary*