title: Comparison of saline and streptokinase-streptodornase in the treatment of leg ulcers.
abstract: In 31 patients with leg ulcers the wounds were randomly allocated to treatment either with a solution of streptokinase plus streptodornase in saline or physiological saline alone. The occurrence of pus and debris in the wounds was evaluated by a "blinded" investigator at the initiation of treatment and on Days 5, 10 and 15. In 12 out of 13 patients treated with the streptokinase-streptodornase solution and in 8 out of 16 saline-treated patients the wounds were clean by Day 10.
authors.forename: E
authors.initials: E
authors.lastname: Forsling
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013299:Streptodornase and Streptokinase / Q000627:therapeutic use*
chemical_list: D013299:Streptodornase and Streptokinase