[Giant lymph nodes in combined autoimmune neutro- and thrombocytopenia].
A boy aged 15 years is described in whom a combined autoimmune neutro- and thrombocytopenia developed since the age of 11. Cell-membrane bound IgG antibodies were detected on neutrophils and platelets. A therapy with prednisone and/or immunoglobulins showed only a transient normalization of the peripheral blood values. In the course of this disease a lymph node adenopathy occurred showing histologically follicle hyperplasia with multiple plasma cells and relative atrophy of the paracortical T-cell region.
Schneider
H
H
Universitäts-Kinderklinik, Freiburg.
Jobke
A
A
Böhm
N
N
D000380:Agranulocytosis / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000276:immunology* / Q000473:pathology; D005871:Castleman Disease / Q000276:immunology*; D002648:Child; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000032:analysis; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009503:Neutropenia / Q000276:immunology* / Q000473:pathology; D013921:Thrombocytopenia / Q000276:immunology* / Q000473:pathology
D001323:Autoantibodies; D007074:Immunoglobulin G
Riesenlymphknoten bei kombinierter Autoimmun-Neutro- und Thrombozytopenie.