Direct separation of drug enantiomers by high-performance liquid chromatography with chiral stationary phases.
The development of chiral stationary phases for HPLC has resulted in renewed interest in methods for the separation of drug enantiomers. This paper provides a brief overview of some of the more recent approaches to the direct resolution of drug enantiomers by HPLC with particular emphasis on their quantification in biological fluids.
Mehta
A C
AC
Department of Pharmacy, General Infirmary, Leeds, Yorkshire, U.K.
D002851:Chromatography, High Pressure Liquid; D004364:Pharmaceutical Preparations / Q000302:isolation & purification*; D013237:Stereoisomerism
D004364:Pharmaceutical Preparations