title: Group G streptococcal endocarditis: two case reports, a review of the literature and recommendations for treatment.
abstract: Two cases of endocarditis caused by a group G streptococcus are reported and the literature on group G streptococcal endocarditis is reviewed. The onset of illness is usually acute and the portal of entry for the organism through the skin. The left side of the heart is mainly involved and in about 50% cases the endocarditis arises on a normal valve. Most patients develop complications, both embolic and cardiac, and the mortality is high (36%). We suggest that patients with proven group G streptococcal endocarditis should be treated with large doses of benzyl penicillin and with an aminoglycoside for not less than 4 weeks. Patients with complications should be referred to a cardiothoracic centre. We should be glad to know details of complications, treatment and outcome in other cases of group G streptococcal endocarditis.
authors.affiliation: Department of Medical Microbiology, St George's Hospital Medical School, London, U.K.
authors.forename: E G
authors.initials: EG
authors.lastname: Smyth
authors.forename: A P
authors.initials: AP
authors.lastname: Pallett
authors.forename: R N
authors.initials: RN
authors.lastname: Davidson
mesh_terms: D000208:Acute Disease; D000328:Adult; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D010401:Penicillin G Benzathine / Q000008:administration & dosage / Q000627:therapeutic use; D013290:Streptococcal Infections; D013291:Streptococcus / Q000302:isolation & purification
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D010401:Penicillin G Benzathine