title: [The specificity of the interaction of the cholinesterases in Far Eastern squid and certain vertebrates with reversible inhibitors].
abstract: Studies have been made of the effect of three groups of ammonia reversible inhibitors on the activity of erythrocyte acetylcholinesterase, serum butyrylcholinesterase, cholinesterase from frog brain, as well as cholinesterases from the optical ganglia of the Pacific and three populations of the commander squids. Determination of kinetic parameters of the reversible inhibition of these enzymes revealed differences resulting from the specific structure of their catalytic centers. Tetramethylammonium assay confirmed different properties of cholinesterases in individuals of the commander squid from various habitats in the Bering Sea; this finding may be taken as an indication of intraspecific differentiation of these cephalopods. Certain similarity was noted in the inhibitory specificity of cholinesterases from the Pacific and "southern" commander squids with the overlapping habitats.
authors.forename: E V
authors.initials: EV
authors.lastname: Rozengart
authors.forename: T N
authors.initials: TN
authors.lastname: Viniar
authors.forename: N N
authors.initials: NN
authors.lastname: Kovalev
authors.forename: A E
authors.initials: AE
authors.lastname: Khovanskikh
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D002802:Cholinesterases / Q000378:metabolism*; D049832:Decapodiformes / Q000378:metabolism*; D004347:Drug Interactions; D004912:Erythrocytes / Q000187:drug effects / Q000201:enzymology; D006736:Horses; D006801:Humans; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D011896:Rana temporaria; D013045:Species Specificity; D013379:Substrate Specificity / Q000187:drug effects; D014714:Vertebrates / Q000378:metabolism*
chemical_list: D002800:Cholinesterase Inhibitors; D000644:Quaternary Ammonium Compounds; D002802:Cholinesterases
vernacular_title: Spetsifichnost' vzaimodeĭstviia kholinésteraz dal'nevostochnykh kal'marov i nekotorykh pozvonochnykh s obratimymi ingibitorami.