[Thymomas and associated diseases. Apropos of a series of 255 surgically treated thymomas].
The authors report on a series of 255 thymomas and the associated diseases most often auto-immune, myasthenia is the disease most frequently encountered (61% of cases). Next, but with a much reduced frequency of around 2%, come other diseases such as hypogammaglobulinaemia, erythroblastopenic anaemia, and disseminated lupus erythematosis. The authors analyse the effect of ablating the thymoma on the associated disease; those with myasthenia are the principal beneficiaries of thymic ablation, 83% in this series experiencing a good response. Besides myasthenia only erythroblastopenic anaemia obtained some benefit from thymic ablation; in all the other cases surgery to the thymic tumour had no benefit on the associated disease. In the light of their own experience the authors made a review of the literature of the different diseases associated with thymomas and made the point of the efficacy of thymectomy in the different diseases.
Levasseur
P
P
Service de Chirurgie Thoracique, Centre Chirurgical Marie-Lannelongue, Le Plessis-Robinson.
Menestrier
M
M
Gaud
C
C
Dartevelle
P
P
Julia
P
P
Rojas-Miranda
A
A
Navajas
M
M
Le Brigand
H
H
Merlier
M
M
D000361:Agammaglobulinemia / Q000150:complications; D000741:Anemia, Aplastic / Q000150:complications; D001327:Autoimmune Diseases / Q000150:complications; D006801:Humans; D009157:Myasthenia Gravis / Q000150:complications; D013934:Thymectomy; D013945:Thymoma / Q000150:complications* / Q000601:surgery; D013953:Thymus Neoplasms / Q000150:complications* / Q000601:surgery
Thymomes et maladies associées. A propos d'une série de 255 thymomes opérés.