title: Sequence-specific chemical modification of a hybrid bacteriophage M13 single-stranded DNA by alkylating oligonucleotide derivatives.
abstract: Alkylating oligonucleotide derivatives react with the complementary sequences in hybrid M13mp7 bacteriophage single-stranded DNA and destroy the infecting ability of the DNA. The reagents do not damage M13mp9 single-stranded DNA lacking the target nucleotide sequence.
authors.affiliation: Institute of Bioorganic Chemistry, Siberian Division of the USSR Academy of Sciences, Novosibirsk.
authors.forename: V V
authors.initials: VV
authors.lastname: Vlassov
authors.forename: V F
authors.initials: VF
authors.lastname: Zarytova
authors.forename: I V
authors.initials: IV
authors.lastname: Kutyavin
authors.forename: S V
authors.initials: SV
authors.lastname: Mamaev
mesh_terms: D000478:Alkylation; D001483:Base Sequence; D003090:Coliphages / Q000235:genetics*; D004249:DNA Damage; D004277:DNA, Single-Stranded / Q000187:drug effects* / Q000235:genetics; D004279:DNA, Viral / Q000187:drug effects* / Q000235:genetics; D005821:Genetic Techniques; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides / Q000494:pharmacology*
chemical_list: D004277:DNA, Single-Stranded; D004279:DNA, Viral; D009838:Oligodeoxyribonucleotides