title: Chemotherapy and hormonal therapy in combination.
abstract: The advantage of adding hormones to chemotherapy for the treatment of patients with breast carcinoma is uncertain, and benefits and disadvantages have been reported. An analysis of published randomized clinical trials reveals that the growth function (differentiation-inducing function v mitogenic function) of the hormone used may determine the ultimate benefit of combined modality treatments.
authors.affiliation: Department of Medical Oncology, M.D. Anderson Hospital and Tumor Institute, Houston, TX 77030.
authors.forename: V
authors.initials: V
authors.lastname: Hug
authors.forename: H
authors.initials: H
authors.lastname: Thames
authors.forename: J
authors.initials: J
authors.lastname: Clark
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000401:mortality / Q000628:therapy*; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005260:Female; D006728:Hormones / Q000627:therapeutic use*; D006801:Humans; D010052:Ovariectomy
chemical_list: D006728:Hormones