A new method of histologic dating of human endometrium in the luteal phase.
Morphometric analysis was performed on 70 endometrial biopsy specimens collected from a population of fertile women. Of the 17 morphometric measurements that were performed on each endometrial biopsy, only 5 were required to achieve a highly significant correlation with chronologic dating based on luteinizing hormone surge (R = 0.99). The result of histologic dating, based on morphometric analysis of endometrial biopsies collected from a separate, unbiased population, correlated strongly and significantly with chronologic dating (r = 0.98, P less than 0.0001). The correlation was better than that achieved when histologic dating was performed according to the conventional dating criteria (r = 0.88, P less than 0.001).
Li
T C
TC
University of Sheffield, Jessop Hospital for Women, England.
Rogers
A W
AW
Dockery
P
P
Lenton
E A
EA
Cooke
I D
ID
D004717:Endometrium / Q000166:cytology*; D005260:Female; D006652:Histological Techniques; D006801:Humans; D008183:Luteal Phase; D007986:Luteinizing Hormone / Q000378:metabolism; D012044:Regression Analysis
D007986:Luteinizing Hormone