[Sterinole and cetylpirydine chloride influence on non-sporulated anaerobic bacteria of oral cavity].
Sensibility (MBC--Minimal Bactericidal Concentration) of 97 strains of non-sporulated anaerobic bacteria separated from clinical material from oral cavity to Sterinole (Polfa) and cetylpirydine chloride has been examined. Experiments have been carried out by means of suspension method adapted appropriately to the tests on non-sporulated anaerobes. 72 hours' cultures of strains containing 10(9) of live bacterial cells in 1 ml have been used as inoculum. MBC readings have been performed after 7 days' incubation at temperature of (37 degrees C) 310 degrees K. From the total number of 97 strains under examinations 34 strains were sensible to low concentration of Sterinole equal to 7.8 to 15.5 micrograms/ml. Further 19 strains exacted MBC within 15.6 to 31.1 micrograms/ml and further 40 strains perished in the antiseptic concentration of 31.2 to 62.4 micrograms/ml. The remaining 4 strains exacted concentration of 62.5 to 125 micrograms/ml to be perished. Among 97 strains 29 strains were perishing in low concentrations of cetylpirydine chloride equal to 7.8 to 15.5 micrograms/ml. Successive 25 strains were damaging by the antiseptic concentration equal to 15.6 to 31.1 micrograms/ml. Further 28 strains exacted utilization of concentration equal to 31.2 to 62.4 micrograms/ml while in case of the remaining 15 strains MBC values achieved the level of 62.5 to 125 micrograms/ml. Strains from Leptotrichia buccalis and then Gram--positive anaerobic bacteria were the most sensitive ones both to Sterinole and cetylpirydine chloride while Gram--negative anaerobic bacteria and anaerobic micrococcus were less sensitive.
Kedzia
A
A
Kałowski
M
M
D001421:Bacteria, Anaerobic / Q000187:drug effects*; D001548:Benzalkonium Compounds / Q000494:pharmacology*; D002594:Cetylpyridinium / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology; D011726:Pyridinium Compounds / Q000494:pharmacology*
D001548:Benzalkonium Compounds; D011726:Pyridinium Compounds; D002594:Cetylpyridinium; C015163:dimethyldodecylbenzylammonium
Działanie sterinolu i chlorku cetylopirydyniowego na nieprzetrwalnikujace bakterie beztlenowe jamy ustnej.