Hepatitis B and renal transplantation.
Renal transplantation in HBsAg+ chronic carriers has a relative low risk of progressive liver disease, with mortality associated with liver disease at 7%. In contrast, HBsAg+ recipients who acquired their disease in the early posttransplant period had a mortality of 60%. HBeAg-positive patients who remain persistently positive are a subgroup with a poor prognosis and should not be offered a renal transplant.
Scott
D
D
Fairfield Infectious Diseases Hospital, Melbourne, Australia.
Mijch
A
A
Lucas
C R
CR
Marshall
V
V
Thomson
N
N
Atkins
R
R
D000328:Adult; D005500:Follow-Up Studies; D006085:Graft Survival; D006509:Hepatitis B / Q000150:complications*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006513:Hepatitis B e Antigens / Q000032:analysis; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*; D011379:Prognosis; D012189:Retrospective Studies
D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens