[Tooth extraction wound healing after administration of vitamin B6 (pyridoxine). Histological study in rats].
Male rats with 250 grs of weight were injected daily with 0.1 ml of B6 vitamin by peritoneal (way paths). The animal were sacrificed at three, seven, 10, 15 and 21 day after the upper incisor extraction. Its hemimaxila were retired and fixed in 10% formalin and after had been embedded in paraffin sections were cut with 6 micrometers pick. The analysis of the sections stained by hematoxylin and eosin when compared with the controls showed that: 1) the blood clot and fibrin net are substituted more rapidly by the granulation tissue; 2) granulation tissue is more plentiful, early and mature; 3) the bone tissue is more plentiful and mature.
de Lucia
M B
MB
Martinelli
C
C
D000818:Animals; D007180:Incisor; D008297:Male; D008437:Maxilla; D011736:Pyridoxine / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains; D014081:Tooth Extraction; D014945:Wound Healing / Q000187:drug effects*
D011736:Pyridoxine
Processo de reparo em feridas de extração dental após administração de vitamina B6 (piridoxina). Estudo histológico em ratos.