title: Antibodies to ovine lymphocytes exist in bovine alloantisera.
abstract: Forty-six percent of 149 reagents against class 1 antigens of the bovine major histocompatibility system reacted with lymphocytes from 1 or more sheep in a microlymphocytotoxicity test. The reactions fell into six groups. The majority of antisera defined an antigen present on both erythrocytes and lymphocytes. This antigen is probably the R blood group antigen and the reactions were unrelated to the presence of anticlass I activity and are probably due to the additional presence of antibodies of R specificity. The other antigens are not identical to any of the 14 red blood cell factors or seven lymphocyte antigens examined, nor did they correspond to any of the class I bovine lymphocyte antigens defined by the alloantisera.
authors.affiliation: Department of Immunology, John Curtin School of Medical Research, Australian National University, Canberra.
authors.forename: M J
authors.initials: MJ
authors.lastname: Stear
authors.forename: P M
authors.initials: PM
authors.lastname: Outteridge
authors.forename: J H
authors.initials: JH
authors.lastname: Dufty
authors.forename: F W
authors.initials: FW
authors.lastname: Nicholas
authors.forename: E M
authors.initials: EM
authors.lastname: Tucker
mesh_terms: D000818:Animals; D000910:Antibodies, Heterophile / Q000032:analysis*; D015478:Antigens, Heterophile / Q000276:immunology; D000961:Antilymphocyte Serum / Q000276:immunology*; D001789:Blood Group Antigens / Q000276:immunology; D002417:Cattle / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D012756:Sheep / Q000097:blood / Q000276:immunology*; D013045:Species Specificity
chemical_list: D000910:Antibodies, Heterophile; D015478:Antigens, Heterophile; D000961:Antilymphocyte Serum; D001789:Blood Group Antigens