Conversion from cyclosporine to azathioprine in heart transplant recipients.
Cyclosporine has proved to be of benefit for heart transplantation. Complications of therapy, however, occasionally require discontinuation of the cyclosporine and replacement with azathioprine. We report two cases in which changing from cyclosporine to azathioprine was followed by fatal rejection episodes.
Stevens
L
L
Section of Cardiovascular Surgery, Methodist Hospital of Indiana, Inc., Indianpolis.
Halbrook
H
H
Berron
K
K
Spears
C
C
Hormuth
D
D
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects*; D003524:Cyclosporins / Q000009:adverse effects*; D006084:Graft Rejection / Q000187:drug effects; D016027:Heart Transplantation; D006801:Humans; D007668:Kidney / Q000187:drug effects; D008297:Male; D008875:Middle Aged
D003524:Cyclosporins; D001379:Azathioprine