Acetylation phenotypes in patients with bladder carcinoma.
The present study was done to evaluate the possible association of bladder carcinoma with the slow acetylator phenotype in a portuguese population. 49 patients with bladder carcinoma were compared to a normal control group of 84 individuals. No statistically significant association was detected. But when subdividing the group of slow acetylators it is found that in the subgroup with 12-36% acetylation there is a higher percentage of patients, which is statistically significant. These results are in agreement with two other studies, using populations of similar ethnic origin.
Bicho
M P
MP
Instituto de Química Fisiológica, Faculdade de Medicina, Lisboa, Portugal.
Breitenfeld
L
L
Carvalho
A A
AA
Manso
C F
CF
D000107:Acetylation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011174:Portugal; D011379:Prognosis; D012016:Reference Values; D013030:Spain; D013418:Sulfamethazine; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000473:pathology
D013418:Sulfamethazine