Reappraisal of AIDS--is the oxidation induced by the risk factors the primary cause?
The emergence of AIDS as a recognizable disease, its epidemiology, the clinical and laboratory data and the way in which they have been interpreted to deduce the currently acceptable hypothesis of its aetiology and mechanism of transmission are critically examined. There is no compelling reason for preferring the viral hypothesis of AIDS to one based on the activity of oxidizing agents. In fact, the latter is to be preferred, since unlike the viral hypothesis it leads to possible methods of prevention and treatment using currently available therapeutic substances.
Papadopulos-Eleopulos
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Royal Perth Hospital, Medical Physics Dept., Western Australia.
D000163:Acquired Immunodeficiency Syndrome / Q000209:etiology*; D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis; D006678:HIV / Q000276:immunology; D015483:HIV Antibodies; D006801:Humans; D010084:Oxidation-Reduction; D012307:Risk Factors
D000914:Antibodies, Viral; D000956:Antigens, Viral; D015483:HIV Antibodies