title: Early secondary suture versus healing by second intention of incisional abscesses.
abstract: A controlled trial was set up to compare the treatment of wound abscesses, occurring after laparotomy, with either early secondary suture combined with cefuroxime and metronidazole given intravenously or by healing by second intention. The secondary suture was performed two days after wound drainage and resulted in a significant reduction (p less than 0.01) in healing time without complications. No reinfections occurred.
authors.affiliation: Department of Surgical Gastroenterology, Herlev Hospital, University of Copenhagen, Denmark.
authors.forename: G G
authors.initials: GG
authors.lastname: Hermann
authors.forename: P
authors.initials: P
authors.lastname: Bagi
authors.forename: I
authors.initials: I
authors.lastname: Christoffersen
mesh_terms: D000038:Abscess / Q000601:surgery; D000328:Adult; D000368:Aged; D002444:Cefuroxime / Q000008:administration & dosage / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004322:Drainage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007813:Laparotomy / Q000009:adverse effects*; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D011897:Random Allocation; D012086:Reoperation; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000601:surgery*; D013536:Suture Techniques; D013997:Time Factors; D014945:Wound Healing
chemical_list: D008795:Metronidazole; D002444:Cefuroxime