title: [Orthotopic liver transplantation in Wilson's disease and acute liver failure].
abstract: Liver histology demonstrated progressive cirrhosis in a 19-year-old girl with a subacute form of Wilson's disease. Despite D-penicillamine administration her liver functions rapidly deteriorated further. Orthotopic liver transplantation was performed. Postoperatively there were two mild rejection episodes, an organic psychiatric syndrome and generalized tremor. Copper metabolism and clinical symptoms became normal postoperatively. Five months after the transplantation she was in a good general condition, able to continue her education.
authors.affiliation: Medizinische Klinik D, Universität Düsseldorf.
authors.forename: G
authors.initials: G
authors.lastname: Kreuzpaintner
authors.forename: W
authors.initials: W
authors.lastname: Lauchart
authors.forename: H
authors.initials: H
authors.lastname: Frenzel
authors.forename: W
authors.initials: W
authors.lastname: Stremmel
authors.forename: W
authors.initials: W
authors.lastname: Berges
authors.forename: R
authors.initials: R
authors.lastname: Pichlmayr
authors.forename: G
authors.initials: G
authors.lastname: Strohmeyer
mesh_terms: D000208:Acute Disease; D000328:Adult; D001706:Biopsy; D005260:Female; D006084:Graft Rejection; D006527:Hepatolenticular Degeneration / Q000150:complications / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000150:complications / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology / Q000628:therapy*; D016031:Liver Transplantation
vernacular_title: Orthotope Lebertransplantation bei Morbus Wilson und akuter Leberinsuffizienz.