title: An open trial of maprotiline for the treatment of cocaine abuse: a pilot study.
abstract: Eleven consecutive severe cocaine abusers were treated openly with maprotiline. Nine completed a 7-week trial, and eight maintained abstinence for at least 1 month as outpatients. Treatment compliance and response appeared better than for a similar group of subjects treated without antidepressants.
authors.affiliation: Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
authors.forename: A W
authors.initials: AW
authors.lastname: Brotman
authors.forename: S M
authors.initials: SM
authors.lastname: Witkie
authors.forename: A J
authors.initials: AJ
authors.lastname: Gelenberg
authors.forename: W E
authors.initials: WE
authors.lastname: Falk
authors.forename: J
authors.initials: J
authors.lastname: Wojcik
authors.forename: L
authors.initials: L
authors.lastname: Leahy
mesh_terms: D000328:Adult; D000873:Anthracenes / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003042:Cocaine; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008376:Maprotiline / Q000008:administration & dosage / Q000627:therapeutic use*; D010349:Patient Compliance; D010865:Pilot Projects; D012189:Retrospective Studies; D019966:Substance-Related Disorders / Q000188:drug therapy*
chemical_list: D000873:Anthracenes; D008376:Maprotiline; D003042:Cocaine