A carbamazepine trial in chronic, treatment-refractory schizophrenia.
Carbamazepine was given to 12 chronic, treatment-refractory schizophrenic patients for 5 weeks. No overall change was found, but four patients significantly improved while eight worsened. Given the paucity of successful treatments for refractory schizophrenia, further study of carbamazepine appears warranted.
Sramek
J
J
Clinical Research Unit, Metropolitan State Hospital, Norwalk, CA 90650.
Herrera
J
J
Costa
J
J
Heh
C
C
Tran-Johnson
T
T
Simpson
G
G
D000328:Adult; D002220:Carbamazepine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy*; D012565:Schizophrenic Psychology
D002220:Carbamazepine