Association of congenital abnormalities of the kidney and urinary tract with those of other organ systems in 13,775 autopsies.
The occurrence of abnormalities of the kidney, urinary tract and other organ systems was reviewed in 13,775 autopsies. Forty-seven percent of 427 autopsies (60% of those under 18) with congenital abnormality of the kidney and urinary tract were found to have an associated abnormality other organ systems. Abnormalities of the cardiovascular (CV) system were most commonly associated with those of the kidney and urinary tract (25%), followed by the gastrointestinal (GI) tract (18%), central nervous system (10%), skeletal (9%), respiratory (8%), facial (7%), reproductive (5%), and chromosome and abdominal wall abnormalities (4% each). Renal and urinary tract abnormalities should be ruled out in any individual presenting with abnormalities of other organ systems, particularly the CV and GI systems and the CNS.
Barakat
A
A
Division of Pediatric Nephrology, Vanderbilt University School of Medicine, Nashville.
Drougas
J G
JG
Barakat
R
R
D000015:Abnormalities, Multiple / Q000453:epidemiology*; D001344:Autopsy; D004065:Digestive System Abnormalities; D006330:Heart Defects, Congenital / Q000453:epidemiology; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D013714:Tennessee / Q000453:epidemiology; D014551:Urinary Tract / Q000002:abnormalities*