Low-temperature study of the A-DNA fragment d(GGGCGCCC).
The structure of the A-type duplex d(GGGCGCCC) was determined from data measured at 115 K to 2.0 A resolution. The space group, P4(3)2(1)2, is the same as for the 293 K structure; cell dimensions are a = 42.74 (4), c = 24.57 (1) A; R = 0.21 for 1694 observed reflections. The conformation and hydration are similar at the two temperatures. The average displacement parameters (B) for bases, sugars and phosphates all decrease by about 9 A2 relative to those found at 293 K. The individual values of B1/2 are linearly related to the distance from the molecular center of mass.
Eisenstein
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M
Department of Structural Chemistry, Weizmann Institute of Science, Rehovot, Israel.
Hope
H
H
Haran
T E
TE
Frolow
F
F
Shakked
Z
Z
Rabinovich
D
D
D001483:Base Sequence; D004247:DNA; D005615:Freezing; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides; D014961:X-Ray Diffraction / Q000379:methods
D009838:Oligodeoxyribonucleotides; D004247:DNA