Analgesic nephropathy.
Analgesic nephropathy has been a recognized clinical problem for the past three decades. The association between chronic renal insufficiency and habitual analgesic consumption initially focused on combination analgesics containing phenacetin. Most recently, the increased popularity of nonsteroidal anti-inflammatory drugs has led to the recognition that these agents are capable of producing several distinct clinical syndromes. This review discusses both of these disorders from a clinical perspective.
Henrich
W L
WL
University of Texas, Southwestern Medical Center, Dallas.
D000707:Anaphylaxis / Q000139:chemically induced; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D004338:Drug Combinations; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D007681:Kidney Papillary Necrosis / Q000139:chemically induced; D009395:Nephritis, Interstitial / Q000139:chemically induced; D011379:Prognosis; D019966:Substance-Related Disorders / Q000150:complications; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004338:Drug Combinations