title: IgG subclasses to food antigens.
abstract: Involvement of sub-classes of IgG that are specific for food allergens in anaphylactoid reactions and some manifestations of atopy no longer needs to be shown. Accordingly, sub-classes of IgG specific for ovalbumin (OVA) and beta-lactoglobulin (BLG) were compared in healthy subjects and those who presented with an intolerance or food allergy to OVA and BLG to decide whether a restrictive diet was necessary. The four sub-classes of IgG1, IgG2, IgG3 and IgG4 were isolated in all the groups. IgG4 was highest in the allergic subjects and the IgG sub-class values were modified by the diet differently in each group. Unfortunately, the small number of subjects does not allow the formation of a definite conclusion to this study.
authors.affiliation: Department of Allergy and Clinical Immunology, University La Sapienza, Rome, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Quinti
authors.forename: C
authors.initials: C
authors.lastname: Papetti
authors.forename: G
authors.initials: G
authors.lastname: D'Offizi
authors.forename: G
authors.initials: G
authors.lastname: Cavagni
authors.forename: M L
authors.initials: ML
authors.lastname: Panchor
authors.forename: C
authors.initials: C
authors.lastname: Lunardi
authors.forename: R
authors.initials: R
authors.lastname: Paganelli
mesh_terms: D000941:Antigens / Q000276:immunology*; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000145:classification*; D007782:Lactoglobulins / Q000276:immunology*; D010047:Ovalbumin / Q000276:immunology*
chemical_list: D000941:Antigens; D007074:Immunoglobulin G; D007782:Lactoglobulins; D010047:Ovalbumin