Elevated serum beta-2-microglobulin--a prognostic marker for development of AIDS among patients with persistent generalized lymphadenopathy.
For evaluation of its prognostic value, the level of serum beta-2-microglobulin was determined in early serum samples from 88 patients with persistent generalized lymphadenopathy in a prospective longitudinal study. Patients with serum beta-2-microglobulin greater than 2.6 mg/l were found to have a significantly higher risk of developing AIDS earlier when compared to patients with a lower level (p less than 0.001).
Morfeldt-Månson
J
J
Department of Infectious Diseases, Roslagstull Hospital, Karolinska Institute, Stockholm.
Julander
I
I
von Stedingk
L V
LV
Wasserman
J
J
Nilsson
B
B
D000386:AIDS-Related Complex / Q000097:blood*; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis*; D006801:Humans; D008137:Longitudinal Studies; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors; D001613:beta 2-Microglobulin / Q000032:analysis*
D001613:beta 2-Microglobulin