Different patterns of cognitive slowing produced by Alzheimer's disease and normal aging.
Aging has previously been shown to produce a generalized proportional slowing of all cognitive operations. In contrast, the present results suggested that Alzheimer's disease produces a disproportionate reduction in the speed with which patients carry out one or more mental operations. The tasks that demented patients found particularly difficult involved either a self-directed search of their lexicon or the use of familiarity information.
Nebes
R D
RD
Department of Psychiatry, University of Pittsburgh, Pennsylvania 15213.
Madden
D J
DJ
D000368:Aged; D000544:Alzheimer Disease / Q000523:psychology*; D005556:Form Perception; D006801:Humans; D008568:Memory; D011939:Mental Recall; D010364:Pattern Recognition, Visual; D011930:Reaction Time; D012016:Reference Values; D014706:Verbal Learning