HLA-DP antigens provide the proliferative impetus for the generation of cytotoxic T lymphocytes.
Investigating HLA-A, -B, -C, -DR and -Dw antigens and MLR, CML, and PLT reactivity in two unrelated persons, it was found that, despite their HLA-D/DR identity, cytotoxic T lymphocytes (CTL) could be induced in the CML assay. The HLA-DP antigens proved to provide the proliferative impetus for the generation of CTL.
Buc
M
M
Department of Microbiology and Immunology, Medical Faculty, Comenius University, Bratislava, Czechoslovakia.
Porubská
S
S
Bencova
M
M
Nyulassy
S
S
Stefanovic
J
J
D002455:Cell Division; D006682:HLA-DP Antigens / Q000276:immunology*; D006801:Humans; D013602:T-Lymphocytes, Cytotoxic / Q000166:cytology / Q000276:immunology*
D006682:HLA-DP Antigens