title: Multifocal eosinophilic granuloma.
abstract: A 22-year-old black male presented with progressive dyspnea, a nonproductive cough, and new skin lesions. He was severely hypoxic, and had a severe restrictive defect on pulmonary function testing. A 2-cm lytic defect was noted on skull radiographs. A lung biopsy demonstrated pulmonary fibrosis. A biopsy of a skin lesion was consistent with a diagnosis of multifocal eosinophilic granuloma, or disseminated histiocytosis X. The case presents several unusual features of this uncommon disorder.
authors.affiliation: Department of Internal Medicine, University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine, Stratford.
authors.forename: T F
authors.initials: TF
authors.lastname: Morley
authors.forename: S D
authors.initials: SD
authors.lastname: Silverstein
authors.forename: J C
authors.initials: JC
authors.lastname: Giudice
authors.forename: R S
authors.initials: RS
authors.lastname: Csere
mesh_terms: D000328:Adult; D004803:Eosinophilic Granuloma / Q000175:diagnosis; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D008297:Male; D011658:Pulmonary Fibrosis / Q000175:diagnosis