Alpha-naphthyl-acetate-esterase activity in cerebrospinal fluid cells.
Mono-histiocytes and T-lymphocytes were assessed by the cytochemical alpha-naphthyl-acetate-esterase (ANAE) stain in 50 CSF samples of patients with various neurological diseases. The ANAE-activity of lymphocytes was decreased in multiple sclerosis and subacute sclerosing panencephalitis, while the activity of mono-histiocytes was increased in the group of infarctions and bacterial and viral infections of the central nervous system. In bacterial meningitis and viral meningo-encephalo-radiculitis the number of ANAE-positive lymphocytes increased after treatment and clinical improvement. ANAE staining appears to be a useful additional tool in CSF cytology in these conditions.
De Reuck
J
J
Department of Neurology, University Hospital, Gent, Belgium.
Vanderdonckt
P
P
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000201:enzymology; D002493:Central Nervous System Diseases / Q000201:enzymology*; D002555:Cerebrospinal Fluid / Q000166:cytology*; D005260:Female; D006098:Granulocytes / Q000201:enzymology; D006644:Histiocytes / Q000201:enzymology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000201:enzymology; D009283:Naphthol AS D Esterase / Q000134:cerebrospinal fluid*; D013601:T-Lymphocytes / Q000201:enzymology
D009283:Naphthol AS D Esterase