title: Pancreatic transplantation in a patient with severe insulin resistance. A case report.
abstract: A 22-year-old white woman with insulin-dependent diabetes mellitus of 20 years' duration and advanced secondary complications underwent pancreatic transplantation for severe insulin resistance and rapidly progressive nephropathy. Resistance to all forms and strengths of subcutaneously administered insulin had necessitated almost permanent hospitalisation for the previous 10 years. Short-term improvement of the endocrine and metabolic status was achieved by initial segmental and subsequent whole pancreatic transplantation.
authors.affiliation: Department of Surgery, University of Stellenbosch.
authors.forename: D F
authors.initials: DF
authors.lastname: du Toit
authors.forename: J J
authors.initials: JJ
authors.lastname: Heydenrych
authors.forename: A R
authors.initials: AR
authors.lastname: Coetzee
authors.forename: M
authors.initials: M
authors.lastname: Weight
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007333:Insulin Resistance; D008074:Lipoproteins / Q000097:blood; D016035:Pancreas Transplantation; D013997:Time Factors
chemical_list: D008074:Lipoproteins