Effects of fasting, water deprivation, and adrenal-blocking chemicals on resistance to Escherichia coli challenge.
Fasting for 2 days plus 1 day of feeding resulted in increased resistance to Escherichia coli challenge. If feed during the postfasting period contained metyrapone (a blocker of adrenal synthesis of corticosterone), resistance to E. coli challenge was reduced. Fasting for 1.75 days or water deprivation for 2 days resulted in decreased resistance to E. coli challenge. Deprivation of water for two days of chickens with blocked adrenals resulted in an E. coli challenge response similar to that of controls.
Gross
W B
WB
Chickering
W
W
D000311:Adrenal Glands / Q000187:drug effects*; D000818:Animals; D002645:Chickens / Q000502:physiology*; D003632:Dichlorodiphenyldichloroethane / Q000494:pharmacology*; D004927:Escherichia coli Infections / Q000662:veterinary*; D005215:Fasting; D008797:Metyrapone / Q000494:pharmacology*; D011201:Poultry Diseases / Q000382:microbiology* / Q000503:physiopathology; D014868:Water Deprivation / Q000502:physiology*
D003632:Dichlorodiphenyldichloroethane; D008797:Metyrapone