Pharmacologic therapy of hypertension in blacks.
In summary, hypertensive blacks have an increased overall benefit of therapy in mild hypertension. They also exhibit an accentuated (supersensitive) response to monotherapy with diuretics or calcium channel blockers. They have a blunted response to most beta blocker monotherapy in usual doses, with the possible exceptions of labetalol and pindolol. They also have a blunted response to converting enzyme inhibitor monotherapy, but both beta blocker and converting enzyme responses are equal when diuretic is added.
Hall
W D
WD
Division of Hypertension, Emory University School of Medicine, Atlanta, GA 30303.
D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D044383:Black People; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000208:ethnology; D008297:Male; D014665:Vasodilator Agents / Q000627:therapeutic use
D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D004232:Diuretics; D014665:Vasodilator Agents