[Study of the sensitivity of enteropathogenic bacteria to nifurzide].
Nifurzide, a synthetic antimicrobial agent of the nitrofuran group, was tested on 320 enteropathogenic bacteria. Minimal inhibition concentrations (MIC) (expressed in mg/l) were determined using the standard agar dilution technique. The MICs were excellent for Campylobacter spp. (97 strains), MIC 50:0.5, MIC 90:0.5; slightly higher for Shigella spp. (50 strains) and Aeromonas spp. (22 strains), MIC 50:2, MIC 90:4; and highest for Salmonella spp. (100 strains) and Yersinia enterocolitica (49 strains), MIC 50:8, MIC 90:8.
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D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002167:Campylobacter / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004755:Enterobacteriaceae / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009581:Nitrofurans / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D009581:Nitrofurans; C029924:nifurzide
Etude de la sensibilité des bactéries entéropathogénes au nifurzide.