The role of suggestion in asthma. II. Effects of a bronchoconstrictor drug on bronchial reactivity under bronchoconstrictor or bronchodilator suggestion.
Previous studies have shown that suggestion may modify bronchial reactivity to both inactive diluents and pharmacologically bronchoconstrictor or dilator substances. In our study, 14 patients were subjected to two methacholine challenge tests presented, respectively, as a bronchoconstrictor or as a bronchodilator drug. Forced expiratory volumes in one second were recorded and a PD20 was determined. No significant differences were reported in PD20 values of each patient after the two kinds of suggestion.
Pastorello
E A
EA
2nd Department of Internal Medicine, University of Milan, School of Medicine, Italy.
Codecasa
L R
LR
Gerosa
A
A
Buonocore
E
E
Sillano
V
V
Zanussi
C
C
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D001980:Bronchi / Q000187:drug effects* / Q000503:physiopathology; D001985:Bronchial Provocation Tests; D001993:Bronchodilator Agents; D002648:Child; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D016210:Methacholine Chloride; D008688:Methacholine Compounds; D008875:Middle Aged; D013404:Suggestion
D001993:Bronchodilator Agents; D008688:Methacholine Compounds; D016210:Methacholine Chloride