title: An acoustic aneurysm-detector.
abstract: Intracranial aneurysms have a high prevalence in the adult population; and if they rupture, significant morbidity almost always ensues. However, pulsatile blood flow through aneurysms produces vibrational sound patterns that may be detected extracranially. Thus, an acoustic aneurysm-detector has been developed to detect the sounds produced by intracranial aneurysms prior to rupture. The design is based on the utilization of a hydrophone for signal detection and computational signal processing for signal extraction. Data are examined in the time domain, the frequency domain, and the time-frequency plane. Examples are presented from an animal model and from a patient with a known aneurysm.
authors.affiliation: Department of Neurological Surgery, University of Pittsburgh, PA 15260.
authors.forename: R J
authors.initials: RJ
authors.lastname: Sclabassi
authors.forename: M
authors.initials: M
authors.lastname: Sun
authors.forename: L
authors.initials: L
authors.lastname: Sekhar
authors.forename: J F
authors.initials: JF
authors.lastname: Wasserman
authors.forename: H B
authors.initials: HB
authors.lastname: Blue
mesh_terms: D000328:Adult; D000465:Algorithms; D000818:Animals; D001314:Auscultation / Q000295:instrumentation*; D003936:Diagnosis, Computer-Assisted / Q000295:instrumentation; D004285:Dogs; D004582:Electronics, Medical / Q000295:instrumentation; D004867:Equipment Design; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis*; D012815:Signal Processing, Computer-Assisted; D014159:Transducers