Oral ribavirin treatment of influenza A and B.
A loading dose and short-term administration of oral ribavirin significantly improved symptoms and signs of influenza type A or B infection in 25 patients. The antiviral effect was not significant. No adverse clinical effects or significant laboratory values were observed. Oral treatment of patients with influenza A or B infection might be possible with ribavirin.
Stein
D S
DS
Creticos
C M
CM
Jackson
G G
GG
Bernstein
J M
JM
Hayden
F G
FG
Schiff
G M
GM
Bernstein
D I
DI
D000284:Administration, Oral; D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D009980:Influenza A virus; D009981:Influenza B virus; D007251:Influenza, Human / Q000188:drug therapy* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D012254:Ribavirin / Q000008:administration & dosage* / Q000627:therapeutic use; D012263:Ribonucleosides / Q000008:administration & dosage*; D013997:Time Factors
D012263:Ribonucleosides; D012254:Ribavirin