Regulation of adult and embryonic genes in human leukemia cells.
In this article, we have reviewed studies showing that altered expression of regulatory genes results in activation of embryonic genes in human leukemia cells. These data have led to important new insights as to how mutations in regulatory genes can lead to disease states in man.
Deisseroth
A
A
Department of Medicine, University of California, San Francisco.
Lyding
J
J
D002454:Cell Differentiation; D005786:Gene Expression Regulation; D005809:Genes, Regulator; D005914:Globins / Q000235:genetics; D006801:Humans; D007938:Leukemia / Q000235:genetics*
D005914:Globins