title: [Creutzfeldt-Jakob disease. Clinical aspects and diagnosis based on 2 cases].
abstract: The case histories are presented of two patients with Creutzfeldt-Jakob disease. The clinical diagnosis was confirmed on autopsy. A 51-year-old man and a 63-year-old woman developed--after a period of non-specific prodromal symptoms--a rapidly progressive dementia accompanied by cerebellar, pyramidal and extrapyramidal signs. The clinical features, the course of the disease and the results of investigations are discussed, as well as the differential diagnosis.
authors.forename: F
authors.initials: F
authors.lastname: Holzner
authors.forename: P
authors.initials: P
authors.lastname: Wessely
authors.forename: N
authors.initials: N
authors.lastname: Fast
mesh_terms: D001253:Astrocytes / Q000473:pathology; D001284:Atrophy; D002540:Cerebral Cortex / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D014057:Tomography, X-Ray Computed
vernacular_title: Die Creutzfeldt-Jakobsche Erkrankung. Klinik und Diagnose an Hand von 2 Fällen.