[Treatment of choroid melanoma with a radioactive iodine 125 plaque: initial results of a pilot study].
The present paper reports on the treatment of 9 choroidal melanomas with a prominence of 5 to 8.7 mm, using iodine-125 plaque.


RESULTS
1-1 3/4 years. Radiation dose per hour: 0.3-0.6 Gy, tumor apex 70 Gy, tumor basis 370 Gy; plaque in situ 1 to 2 weeks. Localization of tumor: 2 X close to macula, 2 X extending into macula, 1 X 1 mm from disc. Postoperative regression of all 9 melanomas, by 51% after 1 year. Postoperatively no reduction in bulbus size, rubeosis iridis, cataract, or optic atrophy; however, 2 X reduced visual acuity: 1 X temporary (increase after laser coagulation of neovascularization), 1 X permanent (discrete subretinal gliosis in residual macular half not extending into radiation scar). Visual acuity 6 months postoperatively equal to that after 1-1 3/4 years and in 5 out of the 9 patients 20/100 to 20/30. An attempt is made to correlate the anatomical and functional results with the "tumor surgery in small steps" achieved with iodine-125 plaquing.
Kreissig
I
I
Stanowsky
A
A
Feine
U
U
D000328:Adult; D000368:Aged; D001918:Brachytherapy / Q000379:methods*; D002829:Choroid / Q000473:pathology; D002830:Choroid Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008545:Melanoma / Q000473:pathology / Q000532:radiotherapy*; D008875:Middle Aged; D010865:Pilot Projects; D011879:Radiotherapy Dosage; D014463:Ultrasonography; D014792:Visual Acuity / Q000528:radiation effects
D007457:Iodine Radioisotopes
Die Behandlung des Aderhaut-Melanoms mit radioaktiver Jod-125-Plaque: Erste Ergebnisse einer Pilotstudie.