title: PAG stimulation does not affect primary antibody responses in rats.
abstract: Adult male rats, which had electrodes chronically implanted in the periaqueductal gray (PAG), were immunized with sheep red blood cells (SRBCs). The number of direct and indirect plaque-forming cells (PFCs) in the group receiving PAG stimulation after immunization did not differ significantly from that in the unstimulated group. Thus, the results indicate that short-term PAG stimulation does not suppress antibody-producing activity in the rat.
authors.affiliation: Department of Anesthesiology, Niigata University School of Medicine, Niigata 951 Japan Department of Virology, Niigata University School of Medicine, Niigata 951 Japan.
authors.forename: Ryoko
authors.initials: R
authors.lastname: Noguchi
authors.forename: Chuya
authors.initials: C
authors.lastname: Hamada
authors.forename: Koki
authors.initials: K
authors.lastname: Shimoji
mesh_terms: D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000502:physiology; D004558:Electric Stimulation; D004580:Electronarcosis; D006462:Hemolytic Plaque Technique; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D008297:Male; D010487:Periaqueductal Gray / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000276:immunology
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M