title: Ageing of the vitreous.
abstract: Changes that occur in the vitreous during ageing contribute to a variety of vitreo-retinal disorders. These age-related changes are rheologic, biochemical, and structural in nature. Our current knowledge of these ageing changes is reviewed. Hypotheses for the mechanisms of liquefaction (synchisis senilis) and posterior vitreous detachment are proposed.
authors.affiliation: Eye Research Institute of Retina Foundation, Boston, Massachusetts.
authors.forename: J
authors.initials: J
authors.lastname: Sebag
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000473:pathology*; D002448:Cell Adhesion; D002648:Child; D003094:Collagen / Q000378:metabolism; D005128:Eye Diseases / Q000209:etiology; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D014822:Vitreous Body / Q000378:metabolism / Q000473:pathology*
chemical_list: D006820:Hyaluronic Acid; D003094:Collagen