title: The familial/sporadic distinction as a strategy in schizophrenia research.
abstract: The rationale and limitations of discriminating between cases of schizophrenia with and without a family history are reviewed. It is concluded from the evidence available that, by identifying subgroups of greater aetiological homogeneity, the strategy can be a useful starting point for research into likely causes.
authors.affiliation: Institute of Psychiatry, Maudsley Hospital.
authors.forename: S W
authors.initials: SW
authors.lastname: Lewis
authors.forename: A M
authors.initials: AM
authors.lastname: Reveley
authors.forename: M A
authors.initials: MA
authors.lastname: Reveley
authors.forename: B
authors.initials: B
authors.lastname: Chitkara
authors.forename: R M
authors.initials: RM
authors.lastname: Murray
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000150:complications / Q000523:psychology; D006801:Humans; D012107:Research Design; D012559:Schizophrenia / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics; D014057:Tomography, X-Ray Computed