The beta amyloid protein (AD-AP) cDNA hybridizes in normal and Alzheimer individuals near the interface of 21q21 and q22.1.
The beta amyloid protein gene (AD-AP) has been assigned by in situ hybridization to the vicinity of the 21q21-q22.1 interface, in a normal individual as well as in a patient with Alzheimer disease.
Blanquet
V
V
U 173 INSERM, UA 119 CNRS, Hôpital Necker-Enfants-Malades, Paris, France.
Goldgaber
D
D
Turleau
C
C
Créau-Goldberg
N
N
Delabar
J
J
Sinet
P M
PM
Roudier
M
M
de Grouchy
J
J
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000235:genetics*; D000682:Amyloid / Q000235:genetics*; D016229:Amyloid beta-Peptides; D002874:Chromosome Mapping; D002891:Chromosomes, Human, Pair 21; D004247:DNA / Q000378:metabolism*; D005260:Female; D005796:Genes; D006801:Humans; D009693:Nucleic Acid Hybridization; D012016:Reference Values
D000682:Amyloid; D016229:Amyloid beta-Peptides; D004247:DNA