title: Lymphocyte subpopulations in Lynch syndrome II: an immunocytochemical study on gastrointestinal biopsies. Preliminary report.
abstract: Gastrointestinal biopsies from 18 members of a family with Lynch Syndrome II were evaluated and immunocytochemical studies were made to characterize the phenotypic expression of the tissue's immune populations. The intestinal findings suggest polyclonal B-cell activation related to the T-helper distribution. Our evaluation provides no specific information so far on the management of patients with Lynch Syndrome II.
authors.affiliation: Servizio di Anatomia Patologica, Ospedale A. Di Summa, Brindisi.
authors.forename: S
authors.initials: S
authors.lastname: Senatore
authors.forename: G S
authors.initials: GS
authors.lastname: Jotti
authors.forename: D
authors.initials: D
authors.lastname: Liguori
authors.forename: M
authors.initials: M
authors.lastname: Chetrì
authors.forename: A
authors.initials: A
authors.lastname: Attolini
authors.forename: G
authors.initials: G
authors.lastname: Cristofaro
authors.forename: M
authors.initials: M
authors.lastname: Gabrielli
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D001706:Biopsy; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000276:immunology* / Q000473:pathology; D004064:Digestive System / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008214:Lymphocytes / Q000145:classification / Q000276:immunology*; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D013577:Syndrome
chemical_list: D014408:Biomarkers, Tumor