Haemagglutinins and adherence properties to HeLa and intestine 407 cells of Klebsiella pneumoniae and Klebsiella oxytoca isolates.
The occurrence of haemagglutination (HA) and adherence properties were examined in 50 strains of K. pneumoniae and 17 K. oxytoca strains isolated from humans. All isolates except three exhibited HA activity. Mannose-sensitive haemagglutinins (MSHA) were expressed by the majority of K. pneumoniae strains, but only by one K. oxytoca isolate. Mannose-resistant haemagglutination (MRHA) to human or guinea pig erythrocytes could not be detected; haemagglutinins of the MR/K type were found in both species with similar frequencies. Adhesive properties could be demonstrated in K. pneumoniae as often as in K. oxytoca: About half of the strains adhered to two human cell lines: HeLa and Intestine 407. The incidence of HA activity was similar in adhering and nonadhering strains. A correlation between MSHA, MR/K-HA and adherence to tissue-cultured cells could not be detected.
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D000818:Animals; D001422:Bacterial Adhesion; D002460:Cell Line; D006168:Guinea Pigs; D006367:HeLa Cells; D006384:Hemagglutination; D006386:Hemagglutination Tests; D006388:Hemagglutinins / Q000032:analysis; D006801:Humans; D007709:Klebsiella / Q000472:pathogenicity* / Q000502:physiology; D007711:Klebsiella pneumoniae / Q000472:pathogenicity* / Q000502:physiology; D008358:Mannose
D006388:Hemagglutinins; D008358:Mannose