The histopathology of rectosigmoid biopsies from adults with bloody diarrhea due to verotoxin-producing Escherichia coli.
The histopathology of rectosigmoid biopsies from 20 patients with bloody diarrhea resulting from verotoxin-producing Escherichia coli infection is reported. The biopsies displayed a range of appearances, from normal to mild, nonspecific inflammation to acute infectious-type colitis. Surface-adherent or invasive bacteria were not identified. The morphologic features of infectious colitis and the absence of bacteria suggest that verotoxin may be responsible for the pathologic changes.
Kelly
J K
JK
Pai
C H
CH
Jadusingh
I H
IH
Macinnis
M L
ML
Shaffer
E A
EA
Hershfield
N B
NB
D001427:Bacterial Toxins / Q000302:isolation & purification*; D001706:Biopsy; D003092:Colitis / Q000209:etiology / Q000473:pathology*; D012809:Colon, Sigmoid / Q000473:pathology*; D003967:Diarrhea / Q000209:etiology*; D004926:Escherichia coli / Q000378:metabolism; D004927:Escherichia coli Infections / Q000473:pathology*; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D012007:Rectum / Q000473:pathology*; D022622:Shiga Toxin 1
D001427:Bacterial Toxins; D022622:Shiga Toxin 1