Genetic variability and mapping of peptidase-4 in Anopheles albimanus.
Field-collected and laboratory populations of Anopheles albimanus were analyzed for the presence of variability for the enzyme, peptidase. Four zones of peptidase electromorphs were observed. The Peptidase-4 (Pep-4) locus was analyzed genetically and assigned to a location adjacent to the centromere on the right arm of chromosome 2 by employing crosses involving morphological mutants, allozyme markers, a holandric translocation, and pericentric inversions. The gene sequence (and map distances) on chromosome 2 beginning from the left arm is: brown larva--40--ebony (eb)--centromere--pep-4--?--bent(be)--?--Glutamate oxaloacetate transaminase (Got)--11--Glucose oxidase-2(Go-2)--17--green larva (gl)--9--amber (am)--2--propoxur resistance (prr)--2--red eye (re)--21--6-Phosphogluconate dehydrogenase (6-Pgd)--1--yellow. The crossover frequencies between eb and Pep-4 and Pep-4 and Got were 34 and 16, respectively.
Narang
S K
SK
Seawright
J A
JA
Willis
N L
NL
Suarez
M F
MF
D000483:Alleles; D000818:Animals; D000852:Anopheles / Q000201:enzymology / Q000235:genetics*; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D010450:Endopeptidases / Q000235:genetics*; D005260:Female; D005796:Genes; D014644:Genetic Variation; D008297:Male
D010450:Endopeptidases