title: Progression of the zone of injury in experimental nerve injuries.
abstract: The extent of injury a nerve sustains after different mechanisms of injury is often difficult to determine at the time of injury. This study was designed to define the zone of injury for avulsed and transected nerves in an experimental animal model. We were able to demonstrate a progressive zone of injury in the avulsed nerves which would preclude primary neurorrhaphy while the zone of injury in a transected nerve tended to decrease during the three week period of observation.
authors.affiliation: Section of Plastic and Reconstructive Surgery, University of Chicago, IL 60637.
authors.forename: L S
authors.initials: LS
authors.lastname: Zachary
authors.forename: A L
authors.initials: AL
authors.lastname: Dellon
mesh_terms: D000818:Animals; D001369:Axons / Q000473:pathology; D003094:Collagen / Q000032:analysis; D004487:Edema; D005355:Fibrosis; D006652:Histological Techniques; D008297:Male; D059348:Peripheral Nerve Injuries; D010525:Peripheral Nerves / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve / Q000293:injuries / Q000473:pathology; D013997:Time Factors
chemical_list: D003094:Collagen