title: Clinical approach to the aged brain.
abstract: There are two main clinical manifestations of the aging brain, which appear to be independent of any disease process, namely adaptability and general slowing. Impaired adaptability depends in part on poor function of the homeostatic mechanisms. General slowing affects all levels of nervous activity and can be measured in various ways. Research relevant to the clinical problem is reviewed and evaluated.
authors.affiliation: Institute of Neurology, National Hospital, Queen Square, London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Marshall
mesh_terms: D000375:Aging; D001921:Brain / Q000502:physiology*; D002560:Cerebrovascular Circulation; D003704:Dementia / Q000503:physiopathology; D006801:Humans