title: [Side effects of non-steroidal antirheumatic agents in the lower gastrointestinal tract].
abstract: Peptic gastroduodenal lesions due to nonsteroidal antiinflammatory drugs (NSAID) are well known, but not the adverse effects of these preparations in the lower GI tract. The cases of 5 patients with NSAID-induced colitis are described and the pertinent literature is reviewed, which reveals a wide spectrum of alterations ranging from mild non-specific colitis to acute bleeding or perforation. The most important key to correct diagnosis is a careful drug history, and treatment is to discontinue the NSAID.
authors.forename: R
authors.initials: R
authors.lastname: Güller
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced*; D004008:Diclofenac / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008528:Mefenamic Acid / Q000009:adverse effects; D008875:Middle Aged; D011349:Proctitis / Q000139:chemically induced; D012459:Salicylates / Q000009:adverse effects
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D012459:Salicylates; D004008:Diclofenac; D008528:Mefenamic Acid
vernacular_title: Die Nebenwirkungen nicht-steroidaler Antirheumatika im unteren Gastrointestinaltrakt.