title: A comparison of histamine and methacholine bronchial challenges using the DeVilbiss 646 nebulizer and the Rosenthal-French dosimeter.
abstract: We have compared bronchial challenge with both histamine and methacholine for the tidal breathing method and dosimeter method, using the DeVilbiss 646 nebulizer, in 18 patients with asthma. There was a significant difference between the PC20 FEV1 but not the PD20 FEV1 when either agonist was administered by the different techniques but not by the same method.
authors.affiliation: Academic Department of Respiratory Medicine, St Bartholomew's Hospital, West Smithfield, London.
authors.forename: J B
authors.initials: JB
authors.lastname: Bennett
authors.forename: R J
authors.initials: RJ
authors.lastname: Davies
mesh_terms: D000328:Adult; D001249:Asthma / Q000175:diagnosis*; D001985:Bronchial Provocation Tests / Q000295:instrumentation / Q000379:methods; D002986:Clinical Trials as Topic; D005260:Female; D005541:Forced Expiratory Volume; D006632:Histamine; D006801:Humans; D008297:Male; D016210:Methacholine Chloride; D008688:Methacholine Compounds; D008875:Middle Aged
chemical_list: D008688:Methacholine Compounds; D016210:Methacholine Chloride; D006632:Histamine