[Diffusion of ceftriaxone in bronchial secretions for 24 hours after a single injection].
The authors have determined the bronchi concentration 1 h, 3 h, 6 h and 24 h after a single muscular injection of ceftriaxone in a series a 13 patient with tracheostomy that received ceftriaxone for prophylaxis. In spite of a large inter-individual variability the result is a good mean ceftriaxone concentration during the first 24 h. Theses results confirms the value or a single daily injection in the treatment of pulmonary injection whose germ is sensitive to the drug.
Gehanno
P
P
Service ORL, Hôpital Claude-Bernard, Paris.
Pangon
B
B
Moisy
N
N
D001980:Bronchi / Q000378:metabolism*; D002443:Ceftriaxone / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004058:Diffusion; D006801:Humans; D013997:Time Factors; D014140:Tracheotomy
D002443:Ceftriaxone
Diffusion de la ceftriaxone dans les sécrétions bronchiques sur vingt-quatre heures, après une injection unique.