title: [Cyclosporin A in immunosuppressive therapy of kidney transplants (clinical results in 55 patients)].
abstract: The authors report the results of a clinical study of the use of cyclosporin A plus low-dose steroids in a consecutive series of 55 kidney transplants with follow-up ranging from 6 to 20 months. The clinical results (rejects, immunosuppressant side effects, 12-month survival of transplant and patient) are compared with those of a similar group of patients on "traditional" therapy (azathioprine plus high-dose steroids). The results of the study confirm the efficacy of cyclosporin A in preventing and controlling acute reject crises in the course of allogenic transplant, though many of the problematic issues related its clinico-therapeutic management remain open questions.
authors.forename: P
authors.initials: P
authors.lastname: Dean
authors.forename: L
authors.initials: L
authors.lastname: Boschiero
authors.forename: G F
authors.initials: GF
authors.lastname: Prati
authors.forename: G
authors.initials: G
authors.lastname: Recchia
authors.forename: L
authors.initials: L
authors.lastname: Faccincani
authors.forename: P J
authors.initials: PJ
authors.lastname: Turolla
authors.forename: M
authors.initials: M
authors.lastname: Firpo
mesh_terms: D003524:Cyclosporins / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D011379:Prognosis; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D003524:Cyclosporins; D013256:Steroids
vernacular_title: La ciclosporina A nella terapia immunosoppressiva del trapianto di rene (risultati clinici su 55 pazienti).