Cell aging in vitro: a historical perspective.
This article describes the historical background to the demonstration by Hayflick and Moorhead that human diploid cell strains in culture have limited life-spans. I suggest that the recognition of cell aging in vitro is an example from the biological sciences of a Kuhnian scientific revolution.
Witkowksi
J A
JA
Imperial Cancer Research Fund Laboratories, St. Bartholomew's Hospital, London.
D000818:Animals; D002470:Cell Survival; D002478:Cells, Cultured; D002642:Chick Embryo; D004171:Diploidy; D005347:Fibroblasts; D006367:HeLa Cells; D049673:History, 20th Century; D006801:Humans; D014765:Viral Vaccines
D014765:Viral Vaccines