[Comparative activity of 9 beta-lactamines, clindamycin and metronidazole on strictly anaerobic bacteria].
The in vitro activities of amoxicillin, amoxicillin-clavulanic acid, piperacillin, cefoxitin, cefotetan, cefotaxime, cefmenoxime, ceftizoxime, latamoxef, clindamycin and metronidazole, were determined by agar dilution method for 196 clinical isolates of anaerobic bacteria. No metronidazole resistant strains could be found, 10% of tested strains were resistant to clindamycin. The majority of these strains was susceptible to amoxicillin-clavulanic acid and piperacillin; less than 10% were resistant to latamoxef, cefoxitin, cefotaxime and ceftizoxime; whereas 15 to 20% were resistant to amoxicillin, cefotetan and cefmenoxime.
Derriennic
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M
Reynaud
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Launay
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Courtieu
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D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D002981:Clindamycin / Q000494:pharmacology*; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D047090:beta-Lactams
D000900:Anti-Bacterial Agents; D047090:beta-Lactams; D008795:Metronidazole; D002981:Clindamycin
Activité comparée de neuf bêtalactamines, de la clindamycine et du métronidazole sur les bactéries anaérobies strictes.