title: [Physiologic-biochemical aspects of the toxic effects of oxidants found in the human environment (air, water)].
abstract: This paper gives a review of published data about physiological and biochemical aspects of the toxic effect of oxygen, ozone, hydrogen peroxide, nitrogen oxide and haloid-containing disinfectants on the human body. The mechanism of action of various oxidants in terms of free radical reactions is analyzed. The oxidant sensitivity of membrane structures, sulphydryl compounds, proteins, enzymes, and the genetic apparatus of the cell is evaluated. The effect of oxidants on the function and structure of erythrocytes, red marrow, blood coagulation, immunity, histological and histochemical structure of organs and tissues is described.
authors.forename: Z P
authors.initials: ZP
authors.lastname: Pak
authors.forename: G V
authors.initials: GV
authors.lastname: Lobacheva
mesh_terms: D000393:Air Pollutants / Q000633:toxicity*; D000818:Animals; D006801:Humans; D010084:Oxidation-Reduction; D014873:Water Pollutants / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D000393:Air Pollutants; D014873:Water Pollutants; D014874:Water Pollutants, Chemical
vernacular_title: Fiziologo-biokhimicheskie aspekty toksicheskogo deĭstviia okisliteleĭ, nakhodiashchikhsia v okruzhaiushcheĭ cheloveka srede (vozdukh, voda).