title: The effect of smokeless-tobacco extracts on the growth of oral bacteria of the genus Streptococcus.
abstract: Aqueous tobacco extracts were used to supplement a basic salts solution (BSS) and a microbial medium. Thin-layer chromatography revealed sucrose in only one of four extracts. Discs saturated with extracts (0.1-50 mg/ml) failed to inhibit growth of any of the micro-organisms. Supplementation (10 mg/ml) of BSS with the tobaccos lacking sucrose resulted in augmented growth of Streptococcus mutans, Streptococcus salivarius and Streptococcus sanguis whereas the sucrose-containing brand augmented only Strep. sanguis growth. Thus extracts of these smokeless tobaccos would serve as a growth substrate for three species of oral streptococci which are frequently associated with human dental caries.
authors.affiliation: Department of Microbiology, University of Maryland Dental School, Baltimore 21201.
authors.forename: W A
authors.initials: WA
authors.lastname: Falkler
authors.forename: M L
authors.initials: ML
authors.lastname: Zimmerman
authors.forename: S A
authors.initials: SA
authors.lastname: Martin
authors.forename: E R
authors.initials: ER
authors.lastname: Hall
mesh_terms: D001431:Bacteriological Techniques; D002855:Chromatography, Thin Layer; D010936:Plant Extracts / Q000494:pharmacology; D013291:Streptococcus / Q000254:growth & development*; D014030:Tobacco, Smokeless
chemical_list: D010936:Plant Extracts