title: Oral ciprofloxacin as prophylaxis in transurethral resection of the prostate.
abstract: A new quinolone antibacterial, ciprofloxacin, was evaluated as oral prophylaxis for transurethral resection of the prostate in a randomised controlled trial. A 3-day course of perioperative ciprofloxacin 250 mg twice daily reduced the post-operative infection rate, the post-operative hospital stay and the frequency of infective complications. Ciprofloxacin was well tolerated and no significant haematological or biochemical side effects were detected.
authors.affiliation: Department of Medical Microbiology, London Hospital.
authors.forename: D A
authors.initials: DA
authors.lastname: Murdoch
authors.forename: D F
authors.initials: DF
authors.lastname: Badenoch
authors.forename: E R
authors.initials: ER
authors.lastname: Gatchalian
mesh_terms: D001437:Bacteriuria / Q000150:complications; D002939:Ciprofloxacin / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D011468:Prostatectomy; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000150:complications / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D002939:Ciprofloxacin