title: Detection of a second mechanism of resistance to gentamicin in animal strains of Escherichia coli.
abstract: One mechanism of plasmid-mediated resistance to gentamicin in Escherichia coli strains isolated from animals is due to the synthesis of the aminoglycoside 3-N-acetyltransferase type IV. A second mechanism of plasmid-mediated resistance to gentamicin was detected in animal strains of E. coli in France and is due to the production of the aminoglycoside 3-N-acetyltransferase type II. The molecular relationships among plasmids encoding this enzyme were studied.
authors.forename: E
authors.initials: E
authors.lastname: Chaslus-Dancla
authors.forename: G
authors.initials: G
authors.lastname: Gerbaud
authors.forename: J L
authors.initials: JL
authors.lastname: Martel
authors.forename: M
authors.initials: M
authors.lastname: Lagorce
authors.forename: J P
authors.initials: JP
authors.lastname: Lafont
authors.forename: P
authors.initials: P
authors.lastname: Courvalin
mesh_terms: D000818:Animals; D003227:Conjugation, Genetic; D004269:DNA, Bacterial / Q000302:isolation & purification; D004352:Drug Resistance, Microbial / Q000235:genetics; D004587:Electrophoresis, Agar Gel; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D005839:Gentamicins / Q000494:pharmacology*; D010641:Phenotype; D010957:Plasmids
chemical_list: D004269:DNA, Bacterial; D005839:Gentamicins