Determination of brain death with 123I-IMP and 99mTc-HM-PAO.
Brain imaging with radiolabeled amines, 123I-IMP and 99mTc-HM-PAO, is a rapid, safe, and specific bedside test for confirming brain death in the absence of cerebral blood flow. Therapeutic phenobarbital or thiopental levels do not interfere with the cerebral penetration ability of the lipophilic radiopharmacons.
Schober
O
O
Department of Radiology, Medical School Hannover, West Germany.
Galaske
R
R
Heyer
R
R
D000662:Amphetamines; D001926:Brain Death; D002339:Carotid Arteries; D002560:Cerebrovascular Circulation; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007457:Iodine Radioisotopes; D020367:Iofetamine; D009942:Organometallic Compounds; D010091:Oximes; D004369:Pentetic Acid; D010634:Phenobarbital / Q000097:blood / Q000627:therapeutic use; D013667:Technetium; D019690:Technetium Tc 99m Exametazime; D016284:Technetium Tc 99m Pentetate; D013874:Thiopental / Q000097:blood / Q000627:therapeutic use
D000662:Amphetamines; D007457:Iodine Radioisotopes; D009942:Organometallic Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D013667:Technetium; D004369:Pentetic Acid; D020367:Iofetamine; D013874:Thiopental; D016284:Technetium Tc 99m Pentetate; D010634:Phenobarbital