XY sperm separation for sex selection.
At present, laboratory methods that can successfully differentiate X- from Y-bearing sperm do exist; namely, staining with quinacrine mustard and DNA flow cytometry. However, methods that can successfully and reproducibly separate X- from Y-bearing sperm with resultant functionally intact sperm have yet to be developed. The area of sex selection is under intensive investigation, and a reliable method of separation will undoubtedly become available in the near future. To the extent that these techniques would be used to help couples avoid sex-linked genetic diseases, preimplantation gender selection is ethically justifiable. Social and ethical factors are important considerations in justifying other applications of these techniques.
Batzofin
J H
JH
D000818:Animals; D002469:Cell Separation; D002498:Centrifugation; D002850:Chromatography, Gel; D006224:Cricetinae; D003412:Cricetulus; D004992:Ethics, Medical; D005260:Female; D005453:Fluorescence; D005818:Genetic Engineering; D006801:Humans; D007158:Immunologic Techniques; D008297:Male; D051379:Mice; D012743:Sex Preselection; D013081:Sperm Motility; D013091:Spermatogenesis; D013094:Spermatozoa / Q000145:classification*; D014960:X Chromosome; D014998:Y Chromosome