title: Light and electronmicroscopic studies on Polycel ossicular replacement prostheses.
abstract: Recently, a new form of porous high density polyethylene (Polycel) has been promoted for use in ossicular chain reconstruction. However, we have found no reports of investigation of the fate of this material used for this purpose in either animals or man. This study was undertaken to look at the tissue tolerance and fate of Polycel in the middle ear of gerbils before its extensive use in humans. We present the light and transmission electromicroscopic findings from these prostheses, removed from the middle ear between 1 and 5 months post-implantation. The results are similar to those found with Plastipore, showing a strong foreign body reaction and the likelihood of phagocytic consumption. As with the other porous plastics, we have reservations about the use of Polycel for ossicular reconstruction.
authors.forename: V C
authors.initials: VC
authors.lastname: Cousins
authors.forename: K
authors.initials: K
authors.lastname: Jahnke
mesh_terms: D000818:Animals; D004429:Ear Ossicles / Q000601:surgery*; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology*; D005849:Gerbillinae; D008297:Male; D008854:Microscopy, Electron; D011095:Polyethylenes; D019736:Prostheses and Implants; D013199:Stapes / Q000473:pathology; D013201:Stapes Surgery
chemical_list: D011095:Polyethylenes