title: [Does a single oral dose of famotidine influence the blood alcohol level?].
abstract: Six healthy volunteer medical students (three men and three women) on four separate occasions drank 500 ml of beer or 250 ml of white wine 30 min after having taken 40 mg of famotidine or a placebo (after 48 hours of abstinence and six hours of fasting). Administration of drug or placebo followed a double-blind, randomized protocol. There was no demonstrable effect of famotidine on the serum level of alcohol (maximal values 0.29-0.67 mg/dl) or on the time until maximal serum concentrations of alcohol were reached.
authors.affiliation: Abteilung für Gastroenterologie, Universitätsklinikum Essen.
authors.forename: G
authors.initials: G
authors.lastname: Holtmann
authors.forename: D
authors.initials: D
authors.lastname: Knop
authors.forename: S
authors.initials: S
authors.lastname: Becker
authors.forename: M V
authors.initials: MV
authors.lastname: Singer
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004341:Drug Evaluation; D000431:Ethanol / Q000097:blood*; D015738:Famotidine; D005260:Female; D006801:Humans; D008297:Male; D010919:Placebos; D013844:Thiazoles / Q000008:administration & dosage*
chemical_list: D010919:Placebos; D013844:Thiazoles; D000431:Ethanol; D015738:Famotidine
vernacular_title: Beeinflusst die einmalige orale Einnahme von Famotidin den Blutalkoholspiegel?