Some aspects of DNA polymerase functioning.
The group of DNA polymerases was studied using some new nucleoside 5'-triphosphate analogs with termination substrate properties. Among DNA polymerases tested the least specific appeared reverse transcriptases of retroviruses and the most specific were DNA polymerases alpha type from high eucaryotes including mammalians.
Krayevsky
A A
AA
Institute of Molecular Biology, USSR Academy of Sciences, Moscow.
Kukhanova
M K
MK
Beabealashvilli
R Sh
RSh
Chidgeavadze
Z G
ZG
D000818:Animals; D009189:Avian Myeloblastosis Virus / Q000201:enzymology; D002417:Cattle; D004247:DNA / Q000096:biosynthesis; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism*; D003854:Deoxyribonucleotides / Q000138:chemical synthesis*; D004926:Escherichia coli / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D051381:Rats; D013379:Substrate Specificity; D013604:T-Phages / Q000201:enzymology; D013950:Thymus Gland / Q000201:enzymology
D003854:Deoxyribonucleotides; D004247:DNA; D004259:DNA-Directed DNA Polymerase