title: Growth of retinal capillary endothelia using pericyte conditioned medium.
abstract: Long-term cultures of bovine retinal capillary endothelial cells (BRCEC) have been established using bovine retinal pericyte conditioned medium (PCM). PCM had greater mitogenic activity on BRCEC than unconditioned medium (P less than 0.01). The mitogenic activity of PCM was not cell specific since bovine Tenon's fibroblast conditioned medium also had significant activity. PCM's activity was not enhanced by heparin though it was additive to that of retinal crude extract.
authors.affiliation: Department of Clinical Ophthalmology, Institute of Ophthalmology, London, England.
authors.forename: H C
authors.initials: HC
authors.lastname: Wong
authors.forename: M
authors.initials: M
authors.lastname: Boulton
authors.forename: J
authors.initials: J
authors.lastname: Marshall
authors.forename: P
authors.initials: P
authors.lastname: Clark
mesh_terms: D000818:Animals; D002196:Capillaries / Q000166:cytology; D002417:Cattle; D002478:Cells, Cultured; D003470:Culture Media; D003584:Cytological Techniques; D004848:Epithelium / Q000502:physiology; D012171:Retinal Vessels / Q000166:cytology*
chemical_list: D003470:Culture Media