Oversynthesis of diacetyl and acetoin in a riboflavin deficient mutant of yeast.
The relations of diacetyl and acetoin to flavinogenesis were studied using a variety of the riboflavin deficient mutants of yeast. The results obtained indicated that only the mutant N189-10A, which have a defect in the pathway positioned next to the nucleotide precursor, guanosine triphosphate (GTP), produces prodigeous amounts of diacetyl and acetoin among the mutants and the wild strain used. A close relation of diacetyl and acetoin to riboflavin formation at their substrate level or regulator level was discussed.
Nakajima
K
K
Department of Nutrition, Koshien University Takarazuka, Hyogo, Japan.
Saito
A
A
D000093:Acetoin / Q000378:metabolism*; D002074:Butanones / Q000378:metabolism*; D003931:Diacetyl / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D009154:Mutation; D012256:Riboflavin / Q000096:biosynthesis*; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*
D002074:Butanones; D000093:Acetoin; D003931:Diacetyl; D012256:Riboflavin