[Release of myoglobin in the blood of irradiated swine showing decreased activity of various enzymes--markers of muscle tissue injury].
Dynamics of changes in the level of myoglobin, hematological indices, and activity of certain enzymes (lactate dehydrogenase, hydroxybutyrate dehydrogenase, and creatine phosphokinase) was studied in blood of exposed (103.2 mC/kg) pigs. As the activity of enzymes decreased the myoglobin content of blood increased 5-7 days following irradiation. The effect of radiation was shown to promote the development of hypoxia in the animal body which was indicated by the ECG changes, the release of functionally deficient erythrocytes to blood, and the occurrence of stable vast hemorrhages.
Ul'ianenko
L N
LN
Rott
G M
GM
Rozhinskaia
I V
IV
Ipatova
A G
AG
Burtsev
A I
AI
D000818:Animals; D003402:Creatine Kinase / Q000097:blood; D006321:Heart / Q000528:radiation effects; D006884:Hydroxybutyrate Dehydrogenase / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D009132:Muscles / Q000201:enzymology / Q000528:radiation effects*; D009206:Myocardium / Q000201:enzymology; D009211:Myoglobin / Q000097:blood*; D011833:Radiation Injuries, Experimental / Q000097:blood*; D013552:Swine; D014916:Whole-Body Irradiation
D009211:Myoglobin; D007770:L-Lactate Dehydrogenase; D006884:Hydroxybutyrate Dehydrogenase; D003402:Creatine Kinase
Vybros mioglobina v krov' obluchennykh svineĭ pri snizhenii aktivnosti v krovi riada fermentov--markerov povrezhdeniia myshechnoĭ tkani.