title: [The OCCGE (Organisation de Coordination et de Coopération pour la Lutte contre les Grandes Endémies) and the surveillance of the drug sensitivity of Plasmodium falciparum to antimalarials].
abstract: Spreading of chemoresistance from East Africa to Central Africa is a very worrying problem for Western Africa. In fact, chemotherapy of febrile attacks is at present admitted as malaria control strategy in the framework of Primary Health Care. This new strategy is based on the fact that commonly used antimalarial drugs as chloroquine are surely efficacious. Thus, the surveillance of chemosensitivity of Plasmodium falciparum local strains becomes a priority. From studies carried out in Burkina Faso during many years, Centre Muraz of O.C.C.G.E. has organized a surveillance system with several levels: a Reference Center, a National Center for each country and sentinel centers located in the different epidemiological features of the countries. This surveillance concerning many states can allow to detect more quickly some possible problems in relation with chemoresistance and to take measures to limit its impact.
authors.affiliation: Centre de réference de la chimiosensibilité du paludisme, Centre Muraz, Bobo-Dioulasso, Burkina Faso.
authors.forename: A R
authors.initials: AR
authors.lastname: Gbary
authors.forename: T R
authors.initials: TR
authors.lastname: Guiguemde
authors.forename: J B
authors.initials: JB
authors.lastname: Ouedraogo
authors.forename: D
authors.initials: D
authors.lastname: Baudon
authors.forename: C J
authors.initials: CJ
authors.lastname: Douchet
authors.forename: J
authors.initials: J
authors.lastname: Le Bras
authors.forename: J
authors.initials: J
authors.lastname: Breman
mesh_terms: D000354:Africa, Western; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D004351:Drug Resistance; D006801:Humans; D007390:International Agencies / Q000458:organization & administration*; D008288:Malaria / Q000188:drug therapy / Q000469:parasitology*; D010963:Plasmodium falciparum / Q000187:drug effects*
chemical_list: D000962:Antimalarials
vernacular_title: L'O.C.C.G.E. et la surveillance de la chimiosensibilité de Plasmodium falciparum aux antipaludéens.