title: Fetal kidney volume and urine production in cases of fetal growth retardation.
abstract: The amount of amniotic fluid has a close correlation to the function of the fetal renal system. In many cases of fetal growth retardation oligohydramnios is obvious. The aim of this study is the investigation of the hourly fetal urine production rate (HFUPR) and the growth of fetal kidneys during pregnancy in cases of fetal growth retardation and to evaluate the renal participation in the origin of oligohydramnios in cases of growth retardation. In 52 healthy pregnancies and 27 cases with known fetal growth retardation, the volume of the fetal kidneys was measured sonographically and the hourly rate of fetal urine production was determined. Two third of the patients with fetal growth retardation had obvious oligohydramnios. In cases of fetal growth retardation the volume of the fetal kidneys was significantly smaller when compared to the control group, and the volume of fetal urine production was significantly lower. The reduced perfusion of the fetal kidneys in those cases with fetal growth retardation may be the reason for the reduction of the HFUPR. Due to the fact that HFUPR is a dynamical parameter and in close relationship to the perfusion of the fetal kidneys, the identification and measurement of this parameter may help to detect subacute and imminent fetal distress in cases of sonographically proven fetal growth retardation.
authors.affiliation: Second Department of Obstetrics and Gynecology, University of Vienna, Austria.
authors.forename: J
authors.initials: J
authors.lastname: Deutinger
authors.forename: W
authors.initials: W
authors.lastname: Bartl
authors.forename: C
authors.initials: C
authors.lastname: Pfersmann
authors.forename: J
authors.initials: J
authors.lastname: Neumark
authors.forename: G
authors.initials: G
authors.lastname: Bernaschek
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000502:physiology; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D007668:Kidney / Q000196:embryology* / Q000503:physiopathology; D011247:Pregnancy; D014463:Ultrasonography; D014556:Urine