Temperature sensitivity of the multiplication of bacteriophage T4 amber mutants on nonpermissive host: characterization of the phenomenon.
The existence of temperature sensitivity of the multiplication of amber mutants on a nonpermissive host has been established for a considerable number of mutants in tail and head genes and for mutants in some other T4 genes as well. Temperature sensitivity of multiplication appears to be gene specific, and is typical of amber mutants in genes the products of which are not numerous per phage or which play the role of catalytic factor. Moreover, in most cases temperature sensitivity is characteristic of amber mutants in definite gene clusters.
Shalniene
V
V
Institute of Biochemistry, Lithuanian Academy of Sciences, Vilnius, USSR.
Nivinskas
R
R
D004926:Escherichia coli / Q000235:genetics; D005804:Genes, Lethal; D005814:Genes, Viral; D009154:Mutation; D013604:T-Phages / Q000235:genetics / Q000254:growth & development*; D013696:Temperature; D014779:Virus Replication