[Morphological changes in the neuroendocrine system during experimental infection of animals with L-forms of group B Streptococcus].
White rats and mice were subjected to a single intraperitoneal inoculation with a stable L-form of Streptococcus B (strain 090). The hypothalamus, hypophysis and adrenal cortex of the animals were subsequently studied during one year. Progressive degenerative, inflammatory, necrotic and sclerotic changes found in the system hypothalamus-hypophysis-adrenals were due to the bacteria persistence in these organs leading to the disturbance of hormonal homeostasis and development of the system deficiency. There was also the tendency (in 6-12 months after the inoculation) to intensifying regeneration with partial recovery of the organs function.
Khostikian
N G
NG
Vartazarian
N D
ND
Gorina
L G
LG
D000818:Animals; D007030:Hypothalamo-Hypophyseal System / Q000382:microbiology / Q000473:pathology*; D007740:L Forms; D051379:Mice; D009336:Necrosis; D010913:Pituitary-Adrenal System / Q000382:microbiology / Q000473:pathology*; D051381:Rats; D013290:Streptococcal Infections / Q000382:microbiology / Q000473:pathology*; D013292:Streptococcus agalactiae
Morfologicheskie izmeneniia v neĭroéndokrinnoĭ sisteme pri éksperimental'nom infitsirovanii zhivotnykh L-formoĭ streptokokka gruppy B.