Old and new techniques together resolve a problem of infection by Salmonella typhimurium.
Isolates of Salmonella typhimurium, recovered over a 9-month period from a child with gastroenteritis, were characterized by biotyping, phage-typing and plasmid-profile analysis. Because the data from the different methods were discrepant, it was difficult to establish whether her infection was due to a single strain that had changed character in vivo or was due to recurrent infections with different, unrelated strains. Restriction-enzyme fingerprinting of the plasmids from the different isolates provided an explanation for the initial discrepancy and high-lighted a source of potential confusion in epidemiological studies.
Platt
D J
DJ
Brown
D J
DJ
Old
D C
DC
Barker
R M
RM
Munro
D S
DS
Taylor
J
J
D001434:Bacteriophage Typing; D005260:Female; D006801:Humans; D007223:Infant; D011815:R Factors; D012008:Recurrence; D012480:Salmonella Infections / Q000382:microbiology*; D012486:Salmonella typhimurium / Q000145:classification* / Q000187:drug effects / Q000235:genetics