title: [Generalized lichen planus with erosive lesions of the penis, treated with thalidomide. Report of a case and review of the literature].
abstract: A patient with generalized lichen planus with lesions in the infrequent localization like face, palms, soles and an extensive erosion of glans penis, is described in a 46 year old patient. He had received various treatment which include systemic steroids, without improvement. After treatment with thalidomide (initial doses 300 mg/day for 2 weeks and 200 mg/day for further 10 weeks) he presents resolution of his lesions and symptomatology. A review of lichen planus etiopathogenesis, making emphasis in the immunological hypothesis is made. As well as the different uses and action mechanism of thalidomide in various inflammatory dermatoses.
authors.affiliation: Servicio de Dermatología, Instituto de Biomedicina, Caracas, Venezuela.
authors.forename: R
authors.initials: R
authors.lastname: Pérez Alfonzo
authors.forename: E
authors.initials: E
authors.lastname: Weiss
authors.forename: J
authors.initials: J
authors.lastname: Piquero Martín
authors.forename: A
authors.initials: A
authors.lastname: Rondón Lugo
mesh_terms: D006801:Humans; D008010:Lichen Planus / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000188:drug therapy* / Q000473:pathology
vernacular_title: Liquen plano generalizado con lesión erosiva del pene, tratado con talidomida. Reporte de un caso y revisión de la literatura.