Effect of ammonium ions on delta 5,7-sterol synthesis in Saccharomyces cerevisiae.
The effect of ammonium concentration in the medium on delta 5,7-sterol synthesis was examined. Higher concentrations of this nitrogen source in the medium decreased sterol synthesis and accumulation during growth. An intermittent supply with ammonium resulted in a proportional synthesis of delta 5,7-sterols and biomass. The carbon to nitrogen molar ratio of greater than or equal to 40 allowed the maximum accumulation of delta 5,7-sterols with our strain of baker's yeast.
Novotný
C
C
Beran
K
K
Bĕhalová
B
B
Dolezalová
L
L
Zajícek
J
J
D000641:Ammonia / Q000378:metabolism*; D002244:Carbon / Q000378:metabolism; D003470:Culture Media; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000378:metabolism; D013261:Sterols / Q000096:biosynthesis*
D003470:Culture Media; D013261:Sterols; D002244:Carbon; D000641:Ammonia