Alpha interferon clinical trial for multiple sclerosis: design considerations.
The design and course of a placebo-controlled alpha-2 interferon trial in MS patients are described. No beneficial effect of the interferon on the course of MS could be shown.
Alter
M
M
Greenstein
J
J
Camenga
D
D
LaRue
L
L
D000328:Adult; D002986:Clinical Trials as Topic / Q000379:methods; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000503:physiopathology
D007370:Interferon Type I