The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression.
The HL-60 cell line, derived from a single patient with acute promyelocytic leukemia, provides a unique in vitro model system for studying the cellular and molecular events involved in the proliferation and differentiation of normal and leukemic cells of the granulocyte/monocyte/macrophage lineage.
Collins
S J
SJ
Molecular Medicine Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98104.
D002454:Cell Differentiation; D002455:Cell Division; D002460:Cell Line; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000473:pathology; D009857:Oncogenes