Cellular composition of spleen and peritoneal exudate in mice after injection of cyclophosphamide-treated L 1210 leukemia cells.
The composition of peritoneal exudate and spleen cells of CD2F1 mice after fourfold i.p. administration of L 1210 leukemia cells treated with cyclophosphamide (L 1210-CY cells) were examined. The number of cells in peritoneal cavity did not increase, however, the spleen weight rose after administration of L 1210-CY cells. The per cent of lymphocytes T was increased 2.5 times but the content of macrophages and lymphocytes B was normal in the peritoneal cavity after L 1210-CY cells injections. In the spleen an 1.4 times increase of the per cent of lymphocytes B, but normal level of macrophages and lymphocytes T were observed.
Skórski
T
T
Kawalec
M
M
Kawiak
J
J
D000818:Animals; D001202:Ascitic Fluid / Q000473:pathology*; D001402:B-Lymphocytes / Q000473:pathology; D003520:Cyclophosphamide / Q000494:pharmacology*; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D007939:Leukemia L1210 / Q000473:pathology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008811:Mice, Inbred DBA; D009368:Neoplasm Transplantation; D013154:Spleen / Q000473:pathology*; D013601:T-Lymphocytes / Q000473:pathology
D003520:Cyclophosphamide