title: Delayed-type allergy against various insulin preparations including human semisynthetic insulin.
abstract: The authors present a patient with delayed-type allergy against insulin preparations of different species including highly purified monocomponent insulin and human semisynthetic insulin. Positive results for cutaneous delayed-type hypersensitivity and for lymphocyte blastogenesis suggested a type IV immunopathogenic reaction. Intradermal tests performed with various components of insulin preparations revealed delayed-type allergy to insulins of different species (bovine, porcine and human) but not to any of the other components.
authors.forename: M I
authors.initials: MI
authors.lastname: Würzburger
authors.forename: G M
authors.initials: GM
authors.lastname: Prelević
authors.forename: N
authors.initials: N
authors.lastname: Despotović
authors.forename: S
authors.initials: S
authors.lastname: Vucković
authors.forename: S D
authors.initials: SD
authors.lastname: Brkić
authors.forename: M
authors.initials: M
authors.lastname: Bozović
authors.forename: D
authors.initials: D
authors.lastname: Nastić-Mirić
mesh_terms: D004342:Drug Hypersensitivity / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007328:Insulin / Q000009:adverse effects*; D008875:Middle Aged; D012882:Skin Tests
chemical_list: D007328:Insulin