The choice of computational unit in the statistical analysis of unbalanced clinical trials.
Clinical periodontal research often involves the treatment of patients who have disease at several sites in the mouth. Should the units of analysis be the patients, the sites, or a combination of both? These strategies are explored and a worked example given.
Osborn
J
J
London School of Hygiene and Tropical Medicine, UK.
D000704:Analysis of Variance; D002986:Clinical Trials as Topic; D006801:Humans; D010510:Periodontal Diseases / Q000628:therapy*; D011897:Random Allocation; D012107:Research Design; D013223:Statistics as Topic