title: Fibrocystic change and fibrocystic disease of the breast.
abstract: The prominence of fibrocystic change of the breast mandates knowledge of pathophysiology, diagnosis, and treatment on the part of all providing primary care to women. This article reviews cystic, epithelial hyperplastic, and fibrotic changes common to fibrocystic change and fibrocystic disease of the breast. Diagnostic modalities including physical examination technique and needle aspiration are presented, together with the rationale for ultrasonography and mammography. A broad spectrum of treatment options is presented for the clinician.
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University, East Lansing.
authors.forename: B H
authors.initials: BH
authors.lastname: Drukker
authors.forename: W C
authors.initials: WC
authors.lastname: deMendonca
mesh_terms: D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D005348:Fibrocystic Breast Disease / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D005355:Fibrosis; D012739:Gonadal Steroid Hormones / Q000627:therapeutic use; D006801:Humans; D006965:Hyperplasia; D008327:Mammography; D012307:Risk Factors; D014463:Ultrasonography
chemical_list: D004965:Estrogen Antagonists; D012739:Gonadal Steroid Hormones