Trimethoprim-sulfamethoxazole and other sulfonamides.
Trimethoprim-sulfamethoxazole continues to be a useful antibiotic for common outpatient problems such as urinary tract infections, prostatitis, acute exacerbations of chronic bronchitis, and acute otitis media as well as for serious infections of the hospitalized patient including Pneumocystis carinii pneumonia, acute pyelonephritis, and some forms of gram negative meningitis. The other sulfonamides have a limited role.
Foltzer
M A
MA
College of Physicians and Surgeons, Columbia University, New York, New York.
Reese
R E
RE
D000890:Anti-Infective Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D004338:Drug Combinations / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D013420:Sulfamethoxazole / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D013449:Sulfonamides / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D014295:Trimethoprim / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D000890:Anti-Infective Agents; D004338:Drug Combinations; D013449:Sulfonamides; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole