title: Vaccination against contagious caprine pleuropneumonia caused by F38.
abstract: Only F38 isolates of mycoplasma cause classical contagious caprine pleuropneumonia (CCPP). Therefore, research has focused on the development of a vaccine that will prevent serious epidemics of the disease in goats. Goats immunized with two doses of a lyophilized preparation of isolated F38 organisms administered 4 weeks apart were completely immune to experimentally induced CCPP. The minimum immunizing dose was 0.15 mg, and this dose was still effective after storage for 14 months at 4 C and 22 C. The duration of immunity induced by a single dose of lyophilized F38 was at least 12 months.
authors.affiliation: Department of Veterinary Microbiology and Pathology, Washington State University, Pullman.
authors.forename: F R
authors.initials: FR
authors.lastname: Rurangirwa
authors.forename: T C
authors.initials: TC
authors.lastname: McGuire
authors.forename: S
authors.initials: S
authors.lastname: Chema
authors.forename: A
authors.initials: A
authors.lastname: Kibor
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000818:Animals; D000942:Antigens, Bacterial / Q000008:administration & dosage / Q000276:immunology; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000276:immunology; D005069:Evaluation Studies as Topic; D005612:Freeze Drying; D006041:Goats; D007114:Immunization; D009174:Mycoplasma / Q000276:immunology*; D009175:Mycoplasma Infections / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary*; D011014:Pneumonia / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary*; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines