[A case of a probable "cancer family syndrome" presenting four synchronous malignancies of the colon].
A 72-year-old male was admitted because of right lower quadrant pain, Barium enema and total colonoscopy disclosed multiple colon cancers and sequentially, a subtotal colectomy was performed. The resected specimen demonstrated 3 advanced carcinomas and an adenomatous cancer with additional multiple polyps. Investigation of his family history revealed that his mother and his elder sister had died of uterine cancer, and that his elder brother, his nephew, and his niece had been operated on for colorectal cancer. We thus supposed a case of "Cancer Family Syndrome" presenting multiple neoplasms of the colon.
Kawamura
O
O
Dept. of Internal Medicine, Yokohama Sakae Kyosai Hospital.
Harigane
M
M
Ohara
H
H
Satoh
H
H
Oda
M
M
Kojima
M
M
Watanabe
H
H
D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D000368:Aged; D003110:Colonic Neoplasms / Q000235:genetics* / Q000473:pathology; D003111:Colonic Polyps / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000235:genetics / Q000473:pathology; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics* / Q000473:pathology; D010375:Pedigree