title: Antipsychotic effect of buprenorphine in schizophrenia.
abstract: The antipsychotic potency of the partial opiate agonist buprenorphine was evaluated in 10 neuroleptic-free schizophrenic patients suffering from frequent hallucinations, delusions, and severe formal thought disorders. Buprenorphine had a pronounced antipsychotic effect, which lasted about 4 hours, in patients with schizophreniform disorders (N = 4) and paranoid schizophrenia (N = 3).
authors.affiliation: Max Planck Institute for Psychiatry, Munich.
authors.forename: C
authors.initials: C
authors.lastname: Schmauss
authors.forename: A
authors.initials: A
authors.lastname: Yassouridis
authors.forename: H M
authors.initials: HM
authors.lastname: Emrich
mesh_terms: D000328:Adult; D002047:Buprenorphine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003702:Delusions / Q000188:drug therapy; D004311:Double-Blind Method; D005260:Female; D006212:Hallucinations / Q000188:drug therapy; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000188:drug therapy / Q000523:psychology; D012559:Schizophrenia / Q000188:drug therapy*; D012563:Schizophrenia, Paranoid / Q000188:drug therapy / Q000523:psychology; D012565:Schizophrenic Psychology
chemical_list: D002047:Buprenorphine