Endometrial granulocytes in human decidua react with a natural-killer (NK) cell marker, NKH1.
Lymphoid cells in decidualized uterine endometrium in early human pregnancy may be essential for successful implantation and placentation. Endometrial granulocytes are prominent in early pregnancy decidua and express some T-cell associated surface antigens (CD2+, CD7+), but little is known of their function. We report the unusually intense binding of the natural-killer (NK) cell marker NKH1 to endometrial granulocytes, which contrasts with their lack of reactivity with other NK-cell markers.
Ritson
A
A
Department of Pathology, University of Leeds, U.K.
Bulmer
J N
JN
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000032:analysis*; D003656:Decidua / Q000276:immunology*; D005260:Female; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007694:Killer Cells, Natural / Q000276:immunology*; D011247:Pregnancy
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface