title: Broth dilution testing of Candida albicans susceptibility to ketoconazole.
abstract: We performed a detailed investigation of the kinetics of ketoconazole activity in the setting of broth dilution testing of Candida albicans susceptibility. Turbidimetric readings reflected parallel quantitative colony counts. The method of endpoint determination markedly affected the results. Determinations of 50% inhibitory concentrations clearly separated the ketoconazole-resistant strains from the susceptible strains.
authors.forename: C E
authors.initials: CE
authors.lastname: Hughes
authors.forename: R L
authors.initials: RL
authors.lastname: Bennett
authors.forename: W H
authors.initials: WH
authors.lastname: Beggs
mesh_terms: D002176:Candida albicans / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D007654:Ketoconazole / Q000494:pharmacology*; D007700:Kinetics
chemical_list: D007654:Ketoconazole