Chromosome localization of the human renin gene (REN) by in situ hybridization.
Previous studies by Southern blot analysis of human X mouse somatic cell hybrids localized the renin gene to region p21----qter of human chromosome 1. Using a DNA insert encoding exons 2-5, the renin gene was mapped to human chromosome bands 1q25----q32 by in situ hybridization. The sublocalization of the renin gene will facilitate subsequent detailed linkage analysis of human chromosome 1.
McGill
J R
JR
Chirgwin
J M
JM
Moore
C M
CM
McCombs
J L
JL
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D004247:DNA / Q000235:genetics; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D009693:Nucleic Acid Hybridization; D012083:Renin / Q000235:genetics*
D005819:Genetic Markers; D004247:DNA; D012083:Renin