Ultrasound evaluation of tachycardia-induced hydrops in the fetal lamb.
Nonimmune hydrops was induced in six fetal lambs at 120 days' gestation by right atrial pacing at 300 beats/min. Biochemical, hemodynamic, and Doppler parameters were observed and monitored by real-time ultrasound during the creation (18 to 42 hours) and resolution of hydrops. The significant changes seen were hypoproteinemia (34.3 to 29.0 mg/100 ml), venous hypertension (24.6 to 31.3 mm Hg), decreases in thoracic aorta flow, and decreases in systolic/diastolic ratios in the aorta and umbilical artery. These changes were reversed with the discontinuation of pacing and the resolution of fetal hydrops.
Nimrod
C
C
Davies
D
D
Harder
J
J
Iwanicki
S
S
Kondo
C
C
Takahashi
Y
Y
Maloney
J
J
Persaud
D
D
Nicholson
S
S
D000818:Animals; D002304:Cardiac Pacing, Artificial; D004487:Edema / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000209:etiology; D006340:Heart Rate, Fetal; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012756:Sheep; D013610:Tachycardia / Q000150:complications*; D014463:Ultrasonography