[Comparative effect of atenolol and verapamil in exertion angina. A single-blind crossed study with computerized exercise test].
The anti-ischemic activity of Verapamil (360 mg/24 h) is compared with a cardioselective betablocker, Atenolol (100 mg/24 h), in a single blind study with computerized stress tests. Although acting through different mechanisms, and are evaluated indirectly by measurements with equal cardiac work and frequency, the improvement of the performance, the decrease of the sub-denivellation at the end of the stress and the frequency of interruption because of pain, seem approximately similar for both medications.
Douard
H
H
Sermon
F
F
Mora
B
B
Broustet
J P
JP
D000787:Angina Pectoris / Q000188:drug therapy* / Q000503:physiopathology; D001262:Atenolol / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003201:Computers; D005080:Exercise Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D014700:Verapamil / Q000627:therapeutic use*
D001262:Atenolol; D014700:Verapamil
Activité comparée de l'aténolol et du vérapamil dans l'angor d'effort. Etude en simple aveugle croisée par épreuve d'effort informatisée.