title: [Resistance pattern of clinical bacterial isolates. Results of a super-regional multicenter study of the Resistance Study Committee of the Paul Ehrlich Society of Chemotherapy].
abstract: In a multicentre study conducted by the Paul-Ehrlich-Gesellschaft we tested about 3,584 clinical isolates from 25 laboratories towards different chemotherapeutics. Using a microdilution test Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecalis strains regarded as causative pathogens were studied. The data were evaluated for the number, frequency and qualitative characteristics of multiple resistance patterns. None of the strains under test was resistant to all antibiotics tested. Amikacin showed the lowest prevalence of resistance. The significance of such data in the epidemiological control of resistance to chemotherapeutics is discussed.
authors.affiliation: Rheinische Friedrich-Wilhelms-Universität, Institut für Medizinische Mikrobiologie und Immunologie, Bonn.
authors.forename: M
authors.initials: M
authors.lastname: Kresken
authors.forename: B
authors.initials: B
authors.lastname: Wiedemann
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy*; D002442:Ceftazidime / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004352:Drug Resistance, Microbial; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents; D002442:Ceftazidime
vernacular_title: Resistenzmuster klinischer Bakterienisolate. Ergebnisse einer überregionalen multizentrischen Untersuchung der Arbeitsgemeinschaft "Resistenz" in der Paul-Ehrlich-Gesellschaft für Chemotherapie e. V.