Morphometric analysis of cancellous bone of young diabetic and non-diabetic sand rats (Psammomys obesus).
Cancellous vertebral bone of young diabetic sand rats (psammomys obesus) was compared with that of non-diabetic sand rats of the same sex and age. Of 5 morphometric diameters, 3--trabecular area, trabecular surface and osteoblastic surface--showed no statistically significant differences between test and control animals. By contrast, the 2 other parameters determined, namely lacunae containing osteoclasts as well as lacunae devoid of osteoclasts were significantly more numerous in diabetics than in controls.
Silberberg
R
R
Department of Pathology, Hebrew University School of Medicine, Jerusalem, Israel.
D000818:Animals; D003411:Arvicolinae; D003921:Diabetes Mellitus, Experimental / Q000473:pathology*; D005260:Female; D008297:Male; D010006:Osteoblasts / Q000166:cytology; D010010:Osteoclasts / Q000166:cytology; D012016:Reference Values; D013131:Spine / Q000166:cytology / Q000473:pathology*