The familial/sporadic distinction as a strategy in schizophrenia research.
The rationale and limitations of discriminating between cases of schizophrenia with and without a family history are reviewed. It is concluded from the evidence available that, by identifying subgroups of greater aetiological homogeneity, the strategy can be a useful starting point for research into likely causes.
Lewis
S W
SW
Institute of Psychiatry, Maudsley Hospital.
Reveley
A M
AM
Reveley
M A
MA
Chitkara
B
B
Murray
R M
RM
D001921:Brain / Q000000981:diagnostic imaging; D001927:Brain Diseases / Q000150:complications / Q000523:psychology; D006801:Humans; D012107:Research Design; D012559:Schizophrenia / Q000175:diagnosis / Q000209:etiology* / Q000235:genetics; D014057:Tomography, X-Ray Computed