Detection of a second mechanism of resistance to gentamicin in animal strains of Escherichia coli.
One mechanism of plasmid-mediated resistance to gentamicin in Escherichia coli strains isolated from animals is due to the synthesis of the aminoglycoside 3-N-acetyltransferase type IV. A second mechanism of plasmid-mediated resistance to gentamicin was detected in animal strains of E. coli in France and is due to the production of the aminoglycoside 3-N-acetyltransferase type II. The molecular relationships among plasmids encoding this enzyme were studied.
Chaslus-Dancla
E
E
Gerbaud
G
G
Martel
J L
JL
Lagorce
M
M
Lafont
J P
JP
Courvalin
P
P
D000818:Animals; D003227:Conjugation, Genetic; D004269:DNA, Bacterial / Q000302:isolation & purification; D004352:Drug Resistance, Microbial / Q000235:genetics; D004587:Electrophoresis, Agar Gel; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D005839:Gentamicins / Q000494:pharmacology*; D010641:Phenotype; D010957:Plasmids
D004269:DNA, Bacterial; D005839:Gentamicins