[Treatment of uncomplicated duodenal ulcer using cimetidine alone and in combination with pirenzepine. A comparative study].
In a double-blind, randomised trial two drug regimens were compared in a group of 129 patients with uncomplicated duodenal ulcers, 64 receiving cimetidine (800 mg) and pirenzepine (50 mg) at bed-time, 65 receiving cimetidine (800 mg) and a placebo at bed-time. Neither statistically nor clinically was there an important difference in effectiveness and tolerance between the two drug regimens.
Huchzermeyer
H
H
Medizinische Klinik, Klinikum Minden.
Höbel
W
W
Prex
E
E
D000328:Adult; D000368:Aged; D002927:Cimetidine / Q000008:administration & dosage* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010890:Pirenzepine / Q000008:administration & dosage* / Q000627:therapeutic use; D011897:Random Allocation
D010890:Pirenzepine; D002927:Cimetidine
Behandlung des unkomplizierten Ulcus duodeni mit Cimetidin allein und kombiniert mit Pirenzepin. Eine Vergleichsstudie.