title: Proteolytic activities in the supragingival plaque of monkeys (Macaca fascicularis).
abstract: Thirteen peptidase substrates were hydrolysed by this plaque. After fasting the monkeys for 24 h, the rates of hydrolysis of N-leucyl-, N-alanyl-, N-isoleucyl- and N-tyrosyl-2-naphthylamines, glycyl-L-proline 4-nitroanilide, N alpha-benzoyl-DL-arginine-2-naphthylamine and L-leucyglycine were significantly increased. Changes in these peptidase activities may serve to enhance the mobilization of amino acids and peptides, and they may explain why the growth rates of dental-plaque bacteria in vivo are generally unaffected by the availability of the host's diet.
authors.affiliation: Royal College of Surgeons, Dental Research Unit, Downe, Kent, England, U.K.
authors.forename: K
authors.initials: K
authors.lastname: Smith
authors.forename: D
authors.initials: D
authors.lastname: Beighton
mesh_terms: D000818:Animals; D003773:Dental Plaque / Q000201:enzymology*; D005215:Fasting; D008252:Macaca fascicularis; D010447:Peptide Hydrolases / Q000378:metabolism*
chemical_list: D010447:Peptide Hydrolases