title: Neuroendocrine, psychophysiological and subjective reactivity to an alcohol placebo in male alcoholic patients.
abstract: Alteration in neuroendocrine activity associated with the regulation of energy metabolism and food intake may play a role in characterizing the alcohol dependent state. Alcoholics, when compared to controls, demonstrated significantly larger and more rapid glucose and insulin responses following the consumption of a placebo beer, which they believed contained alcohol. The existence of significant correlations between peak neuroendocrine responses and desire to drink, anxiety, as well as psychophysiological responses in alcoholics suggests the potential multivariate nature of the biological/behavioral state associated with alcohol dependence.
authors.forename: Z S
authors.initials: ZS
authors.lastname: Dolinsky
authors.forename: D E
authors.initials: DE
authors.lastname: Morse
authors.forename: R F
authors.initials: RF
authors.lastname: Kaplan
authors.forename: R E
authors.initials: RE
authors.lastname: Meyer
authors.forename: D
authors.initials: D
authors.lastname: Corry
authors.forename: O F
authors.initials: OF
authors.lastname: Pomerleau
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000502:physiology* / Q000523:psychology; D000437:Alcoholism / Q000097:blood*; D001143:Arousal / Q000187:drug effects*; D001515:Beer; D001786:Blood Glucose / Q000378:metabolism; D003463:Cues; D005934:Glucagon / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D008297:Male
chemical_list: D001786:Blood Glucose; D006728:Hormones; D007328:Insulin; D005934:Glucagon; D006854:Hydrocortisone