Effect of insulin on excretion and retention of infused glutamine amide-N in chickens (Gallus domesticus).
1. The purpose of this study was to examine the effects of insulin on urinary excretion and retention of the intravenously infused glutamine amide-15N in chickens. 2. Insulin pretreatment reduced urinary total 15N excretion (P less than 0.05) and enhanced 15N retention in chicken body (P less than 0.05), but it did not affect non protein-15N retained in the liver and blood. 3. Insulin decreased the incorporation of the infused glutamine amide-15N into urinary uric acid as well as the excretion of other N-derived urinary uric acid (P less than 0.05), which resulted in a significant decrease in total urinary uric acid (P less than 0.05). 4. There was no effect of insulin on urinary appearance of the infused glutamine amide-15N in the form of ammonia.
Karasawa
Y
Y
Laboratory of Animal Nutrition and Feed Science, Faculty of Agriculture, Shinshu University, Nagano-ken, Japan.
Koh
K
K
D000641:Ammonia / Q000378:metabolism; D000818:Animals; D002645:Chickens; D005973:Glutamine / Q000378:metabolism*; D007328:Insulin / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D009587:Nitrogen Isotopes; D014527:Uric Acid / Q000378:metabolism
D007328:Insulin; D009587:Nitrogen Isotopes; D005973:Glutamine; D014527:Uric Acid; D000641:Ammonia; D009584:Nitrogen