Vestibulospinal pathway in rabbit includes GABA-synthesizing neurons.
When Fast blue is injected into the rabbit spinal cord it is retrogradely transported into nerve cell bodies located in the medial and the descending vestibular nuclei. Approximately 50% of the Fast blue-positive cells also contain glutamic acid decarboxylase-like immunoreactivity. These neurons presumably synthesize gamma-aminobutyric acid (GABA) and the rabbit vestibulospinal pathway therefore contains a substantial inhibitory component.
Blessing
W W
WW
Department of Medicine, Flinders University of South Australia.
Hedger
S C
SC
Oertel
W H
WH
D000578:Amidines; D000818:Animals; D005455:Fluorescent Antibody Technique; D005968:Glutamate Decarboxylase / Q000032:analysis; D007150:Immunohistochemistry; D008297:Male; D009434:Neural Pathways / Q000032:analysis / Q000166:cytology; D009474:Neurons / Q000145:classification / Q000201:enzymology; D011817:Rabbits; D013116:Spinal Cord / Q000032:analysis* / Q000166:cytology; D014726:Vestibular Nuclei / Q000032:analysis* / Q000166:cytology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism / Q000502:physiology*
D000578:Amidines; C031455:diamidino compound 253-50; D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase