title: [Autoantibody diagnosis in Wegener's granulomatosis].
abstract: Anticytoplasmic antibodies (ACPA) against myelomonocytic cells were demonstrable in 54 of 72 patients with Wegener's granulomatosis (WG). Other autoantibodies (including ANA, AMAb, RF and anti-ENA) were only found in a low frequence and titre. The presence of ACPA correlated with the severity and activity of the disease. These results demonstrated that ACPA is a valuable tool to establish the diagnosis and to monitor disease activity in WG.
authors.forename: G
authors.initials: G
authors.lastname: Lüdemann
authors.forename: J
authors.initials: J
authors.lastname: Lüdemann
authors.forename: B
authors.initials: B
authors.lastname: Nölle
authors.forename: W L
authors.initials: WL
authors.lastname: Gross
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D001323:Autoantibodies
vernacular_title: Autoantikörperdiagnostik bei der Wegenerschen Granulomatose.