title: Familial ossicular malformations: case report and review of literature.
abstract: Familial middle ear ossicular anomalies are rare. We report on a daughter and her mother with congenital conductive hearing loss. Tympanotomy disclosed hypoplasia of long crus of incus whose tip had been replaced with a fibrous strand. A review suggests that middle ear ossicular anomalies may be inherited as autosomal dominant traits. Most individuals were bilaterally affected. Most isolated cases were affected unilaterally.
authors.affiliation: Department of Otolaryngology, School of Medicine, Akita University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Higashi
authors.forename: K
authors.initials: K
authors.lastname: Yamakawa
authors.forename: O
authors.initials: O
authors.lastname: Itani
authors.forename: K
authors.initials: K
authors.lastname: Togawa
mesh_terms: D000328:Adult; D002648:Child; D004429:Ear Ossicles / Q000002:abnormalities* / Q000473:pathology; D005260:Female; D005799:Genes, Dominant; D034381:Hearing Loss / Q000235:genetics*; D006314:Hearing Loss, Conductive / Q000151:congenital / Q000235:genetics*; D006801:Humans; D010375:Pedigree