Ocular side effects of systemic steroid therapy in renal transplant patients.
Sixty-one renal transplant patients were studied for ocular complications of steroid therapy. Twenty patients (32.8%) were found to have posterior subcapsular cataract. Three patients (4.9%) had ocular hypertension. There was no significant correlation between cataract formation and the total dose of steroids, number of rejection episodes, or the period of hemodialysis. HLA-A9 was present in noncataract patients to a greater extent, a statistically significant (P less than .05) finding not reported before to our knowledge.
Debnath
S C
SC
Riyadh Armed Forces Hospital, Saudi Arabia.
Abomelha
M S
MS
Jawdat
M
M
Chang
R
R
Al-Khader
A A
AA
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D002386:Cataract / Q000139:chemically induced*; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D007262:Infusions, Intravenous; D016030:Kidney Transplantation; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects*
D011239:Prednisolone; D008775:Methylprednisolone