Kaposi's sarcoma in a renal transplant patient receiving cyclosporine.
A patient of Middle-Eastern descent developed Kaposi's sarcoma of the skin and lymph nodes after renal transplantation while receiving medical immunosuppression, including the use of cyclosporine. The clinical presentation of this patient resembled that of the HTLV-III-associated Kaposi's sarcoma. The tumors totally regressed seven weeks after cessation of immunotherapy. This case, along with other recently reported cases of Kaposi's sarcoma in postrenal transplant patients receiving cyclosporine, illustrates a rare complication of current immunosuppressive therapy.
Ledley
G S
GS
Department of Internal Medicine, Georgetown University School of Medicine, Washington, DC 20007.
Sulica
V I
VI
Kao
G F
GF
D000328:Adult; D003524:Cyclosporins / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation; D008198:Lymph Nodes / Q000473:pathology; D012514:Sarcoma, Kaposi / Q000209:etiology* / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology
D003524:Cyclosporins