title: Colocalization of (3H)-adenosine accumulation and GABA immunoreactivity in the chicken and rabbit retinas.
abstract: Using combined autoradiography and immunohistochemistry, we have compared (3H)-adenosine accumulation and GABA immunoreactivity in the chicken and rabbit retinas. Colocalization of the two markers was observed in a subset of amacrine cells and in certain cell bodies in the ganglion cell layer in both species and in a few horizontal cells in the chicken retina. Cells that contained only (3H)-adenosine or GABA were also seen. The degree of colocalization differed greatly between the two species. The results demonstrate a morphological relationship between the adenosine and GABA systems and provides information on the possible anatomical substrates underlying at least some types of functional interactions.
authors.affiliation: Department of Ophthalmology, University Hospital of Lund, Sweden.
authors.forename: M T
authors.initials: MT
authors.lastname: Perez
authors.forename: A
authors.initials: A
authors.lastname: Bruun
mesh_terms: D000241:Adenosine / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D002645:Chickens; D007124:Immunoenzyme Techniques; D011817:Rabbits; D012160:Retina / Q000032:analysis* / Q000378:metabolism; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
chemical_list: D005680:gamma-Aminobutyric Acid; D000241:Adenosine