title: The influence of S-adenosylmethionine (SAM) on prolactin in depressed patients.
abstract: Twenty subjects entered a double-blind placebo-controlled trial of SAM in depression. Prolactin concentrations were measured before and after 14 days' treatment. There was a highly significant fall in prolactin concentrations in the SAM-treated group.
authors.forename: C S
authors.initials: CS
authors.lastname: Thomas
authors.forename: T
authors.initials: T
authors.lastname: Bottiglieri
authors.forename: J
authors.initials: J
authors.lastname: Edeh
authors.forename: M W
authors.initials: MW
authors.lastname: Carney
authors.forename: E H
authors.initials: EH
authors.lastname: Reynolds
authors.forename: B K
authors.initials: BK
authors.lastname: Toone
mesh_terms: D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*; D011569:Psychiatric Status Rating Scales; D012436:S-Adenosylmethionine / Q000627:therapeutic use*
chemical_list: D012436:S-Adenosylmethionine; D011388:Prolactin