title: Opiate withdrawal and electro-stimulation. Double blind experiments.
abstract: A rapid detoxification technique for heroin addicts is described. The technique uses an impulsional electric current developed by Limoge. The treatment is nonaggressive, very well tolerated by the addicts and leads to a good psychotherapeutic relationship with the medical staff. A successful physical detoxification is achieved in more than 80% of the cases (this figure is based on 400 patients treated by the method). The technique was subjected to two double-blind experiments. The first experiment tested the real efficacity of the electrical stimulation. The difference between the group of subjects stimulated and the unstimulated control group had a "p-value" which was significant at the 0,5% level. This leads us to believe that the electrical stimulation has a real positive effect. The second experiment reconfirmed the efficacity of the stimulation and showed that 24 hour continuous stimulation was not sufficient to produce a lasting effect. After about 50 hours stimulation a Naloxone test produced little or no reaction in the patients.
authors.affiliation: Centre Carreire, Bordeaux.
authors.forename: F
authors.initials: F
authors.lastname: Ellison
authors.forename: W
authors.initials: W
authors.lastname: Ellison
authors.forename: J P
authors.initials: JP
authors.lastname: Daulouede
authors.forename: J F
authors.initials: JF
authors.lastname: Daubech
authors.forename: B
authors.initials: B
authors.lastname: Pautrizel
authors.forename: M
authors.initials: M
authors.lastname: Bourgeois
authors.forename: J
authors.initials: J
authors.lastname: Tignol
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004599:Electric Stimulation Therapy; D005069:Evaluation Studies as Topic; D005260:Female; D006556:Heroin Dependence / Q000628:therapy*; D006801:Humans; D008297:Male; D009270:Naloxone; D013375:Substance Withdrawal Syndrome / Q000628:therapy; D013997:Time Factors
chemical_list: D009270:Naloxone