Further delineation of the 3-M syndrome with review of the literature.
The 3-M syndrome is a clinically recognizable disorder characterized by prenatal and postnatal growth retardation and a spectrum of consistent minor anomalies. Intelligence seems normal. Inheritance is probably autosomal recessive, with possible expression of the mutant gene in the heterozygote. Three sibs with the 3-M syndrome are reported, together with an extensive review of the pertinent literature.
Hennekam
R C
RC
Clinical Genetics Center Utrecht, The Netherlands.
Bijlsma
J B
JB
Spranger
J
J
D001848:Bone Diseases, Developmental / Q000000981:diagnostic imaging / Q000235:genetics*; D005260:Female; D006130:Growth Disorders / Q000000981:diagnostic imaging / Q000235:genetics*; D006801:Humans; D004204:Joint Dislocations / Q000235:genetics; D008297:Male; D010375:Pedigree; D011859:Radiography; D013577:Syndrome