title: Alpha interferon clinical trial for multiple sclerosis: design considerations.
abstract: The design and course of a placebo-controlled alpha-2 interferon trial in MS patients are described. No beneficial effect of the interferon on the course of MS could be shown.
authors.forename: M
authors.initials: M
authors.lastname: Alter
authors.forename: J
authors.initials: J
authors.lastname: Greenstein
authors.forename: D
authors.initials: D
authors.lastname: Camenga
authors.forename: L
authors.initials: L
authors.lastname: LaRue
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic / Q000379:methods; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D007370:Interferon Type I