title: Deletion of c-fms sequences in the 5q- syndrome.
abstract: Southern blot analyses demonstrated hemizygosity of c-fms sequences in three cases of the 5q- syndrome, cytogenetically characterized by del(5)(q13;q35) or del(5)(q31;q35). In situ hybridization studies revealed a deletion of this oncogene from the 5q- chromosome in two cases; moreover, we localized c-fms to region 5q31-33.
authors.affiliation: Department of Pediatrics II, University of Ulm, Federal Republic of Germany.
authors.forename: C R
authors.initials: CR
authors.lastname: Bartram
authors.forename: J V
authors.initials: JV
authors.lastname: Böhlke
authors.forename: S
authors.initials: S
authors.lastname: Adolph
authors.forename: H
authors.initials: H
authors.lastname: Hameister
authors.forename: A
authors.initials: A
authors.lastname: Ganser
authors.forename: B
authors.initials: B
authors.lastname: Anger
authors.forename: N
authors.initials: N
authors.lastname: Heisterkamp
authors.forename: J
authors.initials: J
authors.lastname: Groffen
mesh_terms: D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D011519:Proto-Oncogenes
chemical_list: D011518:Proto-Oncogene Proteins