Cholinergic effects on constructional abilities and on mnemonic processes: a case report.
The effects of physostigmine on test performance of a patient with multiple cognitive deficits were observed in a double-blind, placebo-controlled study. Scores on tests of learning and memory and tests of visuo-spatial and constructional ability were both improved by physostigmine, while lecithin improved scores only on the former tests.
Sahakian
B
B
Joyce
E
E
Lishman
W A
WA
D000544:Alzheimer Disease / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects*; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000627:therapeutic use; D010830:Physostigmine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011581:Psychological Tests; D011597:Psychomotor Performance / Q000187:drug effects*; D012153:Retention, Psychology / Q000187:drug effects
D010713:Phosphatidylcholines; C026718:physostigmine salicylate; D010830:Physostigmine