title: Experimental manipulations of eating: advances in animal models for studying anorectic agents.
abstract: The material set out in this text has been designed to show the wide range of procedures which have the capacity to modify eating behavior--to produce hyper- or hypophagia, to alter the profile of eating patterns, or to adjust dietary preferences and selection. Accordingly, in investigating anorectic drugs it seems necessary to observe the effects of drug actions in a variety of experimental models. This strategy will provide a more complete description of the effect of a drug, will throw light on the mechanism of action, and will provide a more realistic base for predicting the effects of drugs in man.
authors.affiliation: Laboratorio Neurofarmacologico, Istituto di Richerche Farmacologische Mario Negri, Milano, Italia.
authors.forename: J E
authors.initials: JE
authors.lastname: Blundell
authors.forename: P L
authors.initials: PL
authors.lastname: Thurlby
mesh_terms: D000818:Animals; D001067:Appetite Depressants / Q000494:pharmacology*; D004435:Eating / Q000187:drug effects*
chemical_list: D001067:Appetite Depressants