Mutagenicity testing of ethylene oxide in Escherichia coli strains with different repair capacities.
Mutagenicity of ethylene oxide in Escherichia coli B strains with different repair capacities was studied. Deficiencies in excision repair (uvrA, polA) led to a considerable increase in mutation frequency compared with that in the wild-type strain and in strains deficient in error-prone repair (recA, lexA).
Kolman
A
A
Department of Radiobiology, University of Stockholm, Sweden.
Näslund
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M
D004249:DNA Damage; D004260:DNA Repair / Q000187:drug effects; D004269:DNA, Bacterial / Q000187:drug effects / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D005027:Ethylene Oxide / Q000494:pharmacology*; D005798:Genes, Bacterial / Q000187:drug effects; D009152:Mutagenicity Tests; D013014:SOS Response, Genetics / Q000187:drug effects
D004269:DNA, Bacterial; D005027:Ethylene Oxide