title: Glial cells positive for glial fibrillary acidic protein in the neurohypophysis of the Djungarian hamster (Phodopus sungorus). An immunohistochemical and ultrastructural study.
abstract: The presence and distribution of the glial fibrillary acidic protein (GFAP; an astrocytic marker protein associated with glial filaments) in the neurohypophysis of the Djungarian hamster (Phodopus sungorus) were investigated immunohistochemically. Our study revealed characteristic GFAP-staining patterns within the median eminence, infundibular stem and neural lobe. In the whole neurohypophysis, few glial cells showed immunoreactivity. In the neural lobe, immunopositive pituicytes appeared preferentially in the periphery. At the ultrastructural level, we found some pituicytes containing filaments, most notably in their processes. We thus demonstrated that, in contrast to the GFAP-immunoreactivity of cultured pituicytes, pituicytic GFAP-expression in vivo coincides with the presence of electron-microscopically detectable filaments.
authors.forename: P
authors.initials: P
authors.lastname: Redecker
authors.forename: W
authors.initials: W
authors.lastname: Wittkowski
authors.forename: K
authors.initials: K
authors.lastname: Hoffmann
mesh_terms: D000818:Animals; D006224:Cricetinae; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis*; D007106:Immune Sera; D007124:Immunoenzyme Techniques; D008854:Microscopy, Electron; D009457:Neuroglia / Q000166:cytology* / Q000648:ultrastructure; D010904:Pituitary Gland, Posterior / Q000166:cytology* / Q000648:ultrastructure
chemical_list: D005904:Glial Fibrillary Acidic Protein; D007106:Immune Sera