title: R-plasmid RP1 promotes adhesion of gram-negative bacteria to medical prostheses and glass.
abstract: The presence of R-plasmid RP1 increased the adhesion of chemostat-grown iron- and carbon-limited Proteus mirabilis to the surfaces of various medical prostheses and to glass. Similar results were obtained with iron-limited Pseudomonas aeruginosa and anaerobically-grown Escherichia coli. Changes in the surface properties of P. mirabilis indicated that the R-plasmid-mediated increase in negative charge was one of the factors that promoted adhesion.
authors.affiliation: Department of Pharmaceutical Sciences, Aston University, Birmingham.
authors.forename: J A
authors.initials: JA
authors.lastname: Onaolapo
authors.forename: M I
authors.initials: MI
authors.lastname: el-Haffar
authors.forename: D
authors.initials: D
authors.lastname: Townley
authors.forename: R M
authors.initials: RM
authors.lastname: Klemperer
mesh_terms: D001422:Bacterial Adhesion; D002244:Carbon / Q000378:metabolism; D005898:Glass; D006090:Gram-Negative Bacteria / Q000472:pathogenicity / Q000502:physiology*; D007501:Iron / Q000378:metabolism; D010957:Plasmids; D019736:Prostheses and Implants; D011513:Proteus mirabilis / Q000472:pathogenicity / Q000502:physiology; D013499:Surface Properties
chemical_list: D002244:Carbon; D007501:Iron