title: Oestradiol-17 beta and progesterone level changes in peritoneal fluid around the time of ovulation.
abstract: In 15 women, peritoneal fluid was obtained by either culdocentesis (n = 20) or laparoscopy (n = 3), before (n = 9) and after (n = 14) ovulation. Ultrasound was used for ovulation detection. Before ovulation the mean oestradiol-17 beta level in plasma and peritoneal fluid was not essentially different; the mean progesterone level was significantly higher in peritoneal fluid. After ovulation both the mean oestradiol-17 beta and progesterone levels were significantly higher in peritoneal fluid than in plasma. In peritoneal fluid, there was a wide distribution of individual oestradiol-17 beta values before and after ovulation; no significant difference existed between the mean pre- and postovulatory oestradiol-17 beta level. More consistent changes were seen in peritoneal fluid progesterone levels; the mean level was significantly higher after ovulation. In three subjects, a low postovulatory progesterone level in peritoneal fluid was associated with a cystic luteal structure observed by ultrasound, suggesting a reduced leakage of fluid from the ovulation stigma.
authors.forename: R F
authors.initials: RF
authors.lastname: Kruitwagen
authors.forename: H A
authors.initials: HA
authors.lastname: Janssen-Caspers
authors.forename: J W
authors.initials: JW
authors.lastname: Wladimiroff
authors.forename: R
authors.initials: R
authors.lastname: Schats
authors.forename: F H
authors.initials: FH
authors.lastname: De Jong
authors.forename: A C
authors.initials: AC
authors.lastname: Drogendijk
mesh_terms: D001202:Ascitic Fluid / Q000032:analysis*; D004958:Estradiol / Q000032:analysis* / Q000097:blood; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000097:blood; D010060:Ovulation; D010061:Ovulation Detection; D011374:Progesterone / Q000032:analysis* / Q000097:blood; D014463:Ultrasonography
chemical_list: D011374:Progesterone; D004958:Estradiol