A spontaneous lymphoblastic lymphoma in a guinea-pig.
The exceptional carcinoresistance of guinea-pigs is well known and only a few cases of spontaneous leukaemia and several very rare cases of lymphoma have been reported in the literature. A spontaneous malignant tumor in an old male hybrid guinea-pig is described. The monomorphous aspect of the tumour, the cellular cohesiveness, the "starry-sky" pattern and the immunocytological characterization of tumour cells as B lymphocytes bearing IgM, lead to describe this tumour as a probable spontaneous Burkitt-type malignant lymphoblastic lymphoma.
Debout
C
C
Laboratoire d'Histologie, CHU Côte de Nacre, Caen, France.
Caillez
D
D
Izard
J
J
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology; D002051:Burkitt Lymphoma / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D006168:Guinea Pigs; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D012376:Rodent Diseases / Q000473:pathology*; D012377:Rodentia
D007075:Immunoglobulin M