title: Comparison of Du Pont Isolator and Roche Septi-Chek for detection of fungemia.
abstract: The rapid detection of fungemia in hospitalized patients is imperative, particularly for those who are immunocompromised. Our laboratory compared the Roche Septi-Chek with the Du Pont Isolator for the recovery of fungi from blood. Of 23,586 matched pairs of blood cultures, 199 were positive. The Isolator detected 178 (89.4%) and the Septi-Chek detected 119 (59.7%) of all positive isolates. The mean recovery time for the Isolator and Septi-Chek was 2.2 and 4.9 days, respectively. The Isolator detected fungemia earlier than the Septi-Chek did and was the only culture system positive in 83% of 53 patients, whereas the Septi-Chek system yielded the same results in only 13% of the patients. The Isolator provides a more rapid and sensitive method for the recovery of fungi from blood.
authors.affiliation: Hospital Severo Ochoa, Leganes-Madrid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Guerra-Romero
authors.forename: R S
authors.initials: RS
authors.lastname: Edson
authors.forename: F R
authors.initials: FR
authors.lastname: Cockerill
authors.forename: C D
authors.initials: CD
authors.lastname: Horstmeier
authors.forename: G D
authors.initials: GD
authors.lastname: Roberts
mesh_terms: D001769:Blood / Q000382:microbiology; D002175:Candida / Q000302:isolation & purification; D002176:Candida albicans / Q000302:isolation & purification; D002177:Candidiasis / Q000175:diagnosis; D005658:Fungi / Q000302:isolation & purification*; D006801:Humans; D009181:Mycoses / Q000175:diagnosis*; D012189:Retrospective Studies; D018805:Sepsis / Q000175:diagnosis*