Screening a hybridoma producing a specific monoclonal antibody to HLA-A24+Bw4 antigen by cytotoxicity inhibition assay.
A hybridoma secreting a monoclonal antibody (Tsa-1, IgG3) reacting specifically to HLA-A24+Bw4 was screened by cytotoxicity inhibition assay and micrototoxicity test. The R value of the antibody was 0.843.
Hiroishi
S
S
Kaneko
T
T
Arita
J
J
D000911:Antibodies, Monoclonal / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D006680:HLA Antigens / Q000276:immunology*; D015234:HLA-A Antigens; D059871:HLA-A24 Antigen; D015235:HLA-B Antigens; D006801:Humans; D006825:Hybridomas / Q000276:immunology*; D001613:beta 2-Microglobulin / Q000276:immunology
D000911:Antibodies, Monoclonal; D006680:HLA Antigens; D015234:HLA-A Antigens; D059871:HLA-A24 Antigen; D015235:HLA-B Antigens; C042388:HLA-Bw4 antigen; D001613:beta 2-Microglobulin