title: [Structural proteins of the cytoskeleton as markers for determining tumor histogenesis].
abstract: The data of literature about the structure of cytoskeleton proteins in the normal and malignant cells are analyzed. The possibilities of using a specific polyclonal serum and a monoclonal antibody for a more precise ascertainment of the origin and diagnostic of tumours are discussed. The intermediate and active filaments may be used as a new class of histochemical markers. Laminin, the protein of basement membranes, probably, plays an important role in metastatic spreading.
authors.forename: E M
authors.initials: EM
authors.lastname: Chernovskaia
mesh_terms: D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor; D003598:Cytoskeletal Proteins; D006801:Humans; D007381:Intermediate Filament Proteins
chemical_list: D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor; D003598:Cytoskeletal Proteins; D007381:Intermediate Filament Proteins
vernacular_title: Strukturnye belki tsitoskeleta kak markery dlia opredeleniia gistogeneza opukholeĭ.