[Effect of ionizing radiation on the turnover of catalase-degrading proteinase in rat hepatocytes].
A study was made of the influence of whole-body X-irradiation (8 Gy) on the turnover of an individual protein, alkaline proteinase, initiating inactivation of a catalase protein in rat liver. It was shown that the extent to which metabolism of this enzyme in the exposed animals is impaired depends upon its localization. The authors discuss the possibility of a correlation between the decrease in the catalase protein degradation and the level of proteinase activity in hepatocytes of irradiated rat liver.
Komov
V P
VP
Strelkova
M A
MA
Makeeva
A L
AL
D000818:Animals; D002374:Catalase / Q000378:metabolism*; D003600:Cytosol / Q000201:enzymology / Q000528:radiation effects; D010450:Endopeptidases / Q000528:radiation effects*; D005260:Female; D008099:Liver / Q000201:enzymology / Q000528:radiation effects*; D008830:Microbodies / Q000201:enzymology / Q000528:radiation effects; D008862:Microsomes, Liver / Q000201:enzymology / Q000528:radiation effects; D008930:Mitochondria, Liver / Q000201:enzymology / Q000528:radiation effects; D051381:Rats; D014316:Tritium
D014316:Tritium; D002374:Catalase; D010450:Endopeptidases
Vliianie ioniziruiushcheĭ radiatsii na krugooborot proteinazy, degradiruiushcheĭ katalazu v gepatotsitakh krys.