title: Theory of adequate function of cells and the organism--the theoretical basis for contemporary medicine.
abstract: The theory of adequate function of the cells and the organism is introduced as the theoretical basis for contemporary medicine. In accordance with this theory, the organism tends to function adequately to the needs directed toward the maintenance of life under various conditions. Mechanisms responsible for adequate function include those of regulation, compensation and defense. Their interactions provide for adequate function in both steady and transient physiological conditions, as well as in pathological conditions. Examples of adequate function under various conditions are discussed. The notion of optimal adequate function of cells and the organism is introduced, which implies the complete satisfaction of the needs of the cells and the demands imposed upon these cells by the organism. The dual character of the cell's adequate function contributes to the possibilities for disease. Imbalance between the needs of the cell and the needs of the organism is proposed to be the general mechanism of chronic diseases. Maintenance of the optimal balance of adequate function throughout the life of an individual is considered to be the major objective through which the prophylaxis and early treatment of chronic diseases can be achieved.
authors.forename: A
authors.initials: A
authors.lastname: Yabrov
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D001831:Body Temperature; D002468:Cell Physiological Phenomena; D002908:Chronic Disease / Q000209:etiology; D006706:Homeostasis; D006801:Humans; D007113:Immunity, Innate; D008511:Medicine