title: Immunohistochemical identification of neuron-specific enolase and calbindin in the vestibular receptors of human fetuses.
abstract: Immunohistochemical techniques were used to identify neuron-specific enolase (NSE) and calbindin in the vestibular receptors and ganglia of human fetuses at 10 weeks of gestation. NSE was found in vestibular ganglion cells and in a few sensory cells. The pattern of immunoreactivity in the sensory epithelia was characteristic of the appearance of NSE in these structures. Calbindin was found in vestibular ganglion cells and sensory cells which displayed a strong immunoreactivity. These findings are discussed with regard to synaptogenesis and they indicate that the vestibular receptors show biochemical signs of maturation consistent with the possibility of synaptic activity.
authors.affiliation: INSERM-U. 254, Laboratoire de Neurophysiologie Sensorielle, USTL, Montpellier, France.
authors.forename: C J
authors.initials: CJ
authors.lastname: Dechesne
authors.forename: P
authors.initials: P
authors.lastname: Escudero
authors.forename: N
authors.initials: N
authors.lastname: Lamande
authors.forename: M
authors.initials: M
authors.lastname: Thomasset
authors.forename: A
authors.initials: A
authors.lastname: Sans
mesh_terms: D064026:Calbindins; D005325:Fetal Organ Maturity; D005333:Fetus / Q000033:anatomy & histology*; D006198:Hair Cells, Auditory / Q000032:analysis / Q000201:enzymology; D006801:Humans; D007124:Immunoenzyme Techniques; D010751:Phosphopyruvate Hydratase / Q000032:analysis*; D064030:S100 Calcium Binding Protein G / Q000032:analysis*; D014722:Vestibule, Labyrinth / Q000032:analysis / Q000196:embryology* / Q000201:enzymology
chemical_list: D064026:Calbindins; D064030:S100 Calcium Binding Protein G; D010751:Phosphopyruvate Hydratase