title: Cholinergic effects on constructional abilities and on mnemonic processes: a case report.
abstract: The effects of physostigmine on test performance of a patient with multiple cognitive deficits were observed in a double-blind, placebo-controlled study. Scores on tests of learning and memory and tests of visuo-spatial and constructional ability were both improved by physostigmine, while lecithin improved scores only on the former tests.
authors.forename: B
authors.initials: B
authors.lastname: Sahakian
authors.forename: E
authors.initials: E
authors.lastname: Joyce
authors.forename: W A
authors.initials: WA
authors.lastname: Lishman
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects*; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000627:therapeutic use; D010830:Physostigmine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011581:Psychological Tests; D011597:Psychomotor Performance / Q000187:drug effects*; D012153:Retention, Psychology / Q000187:drug effects
chemical_list: D010713:Phosphatidylcholines; C026718:physostigmine salicylate; D010830:Physostigmine