[Saccharomyces cerevisiae mutants characterized by increased induced mutagenesis. II. Genetic analysis of mutants].
Induction of forward adenine-dependent (Ade+----Ade-) mutations by HAP was used to analyse genetically yeast mutants with enhanced induced mutagenesis. Three mutations studied in detail segregated as a single mendelian trait and composed independent complementation groups (HIM1, HIM2, HIM3). the him1-1 mutation was centromere-linked, the him3-1 and him2-1 mutations being not. All three mutations did not show any cross-linkage. Uracil-DNA glycosylase activity was determined in crude cell extract from wild type strain and him mutants; no detectable differences were observed.
Ivanov
E L
EL
Bulat
S A
SA
Korolev
V G
VG
Koval'tsova
S V
SV
D000225:Adenine / Q000031:analogs & derivatives / Q000633:toxicity; D000483:Alleles; D005800:Genes, Fungal; D009153:Mutagens; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics*
D009153:Mutagens; C032610:6-N-hydroxylaminopurine; D000225:Adenine
Mutanty drozhzheĭ Saccharomyces cerevisiae, kharakterizuiushchiesia povyshennym indutsirovannym mutagenezom. Soobshchenie II. Geneticheskiĭ analiz mutantov.