Sudden infant death syndrome: congenital copper deficiency.
A previous paper describes specific respiratory toxins likely to be associated with Sudden Infant Death Syndrome (SIDS). This paper describes ultrastructural abnormalities in the lung and other tissues in congenital copper deficiency. Congenital copper deficiency is associated with tissue anoxia defects in the development of myelin through a failure of phospholipid synthesis. Phospholipid is part of the membrane structure of cells. The paucity of elastin is attributed to a loss of lysyl oxidase activity. Hypoventilation is considered a feature of SIDS.
Reid
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D000818:Animals; D003300:Copper / Q000172:deficiency*; D004549:Elastin / Q000096:biosynthesis; D006801:Humans; D008168:Lung / Q000378:metabolism / Q000473:pathology; D013398:Sudden Infant Death / Q000209:etiology* / Q000473:pathology
D003300:Copper; D004549:Elastin