[Cellular immunity in prostatic cancer modified by Cytonal, Estrazyt and Turisteron].
The influence on the specific cell-mediated immunity (CMI) of the carcinoma of the prostate gland by the contra-sexual hormone therapy with Cytonal, Estrazyt and Turisteron is controlled. For this purpose the macrophage-electrophoresis-mobility test on the basis of allogenic tumour-associated antigen of the carcinoma of the prostate gland is used. As a result the use of Cytonal at least in the dosage hitherto used is no longer worth being advocated. Turisteron and Estrazyt, respectively, taking into consideration their pharmacokinetics and indication, prove to be immunologically optimal and without hesitation, respectively. Turisteron is the basic therapeutic in the androgen-dependent carcinoma of the prostate gland. Estrazyt should be reserved to primarily and secondarily hormone-refractory tumours. For the application of Estrazyt an additive immune stimulation seems to be worth taking into consideration.
Klebingat
K J
KJ
Panzig
E
E
Lorenz
G
G
Steinhauser
I
I
Fiedler
R
R
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D004054:Diethylstilbestrol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004961:Estramustine / Q000627:therapeutic use*; D004997:Ethinyl Estradiol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D008264:Macrophages / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009588:Nitrogen Mustard Compounds / Q000627:therapeutic use*; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000276:immunology; D011897:Random Allocation
D000970:Antineoplastic Agents; D009588:Nitrogen Mustard Compounds; C025723:ethinyl estradiol sulfonate; D004961:Estramustine; D004997:Ethinyl Estradiol; D004054:Diethylstilbestrol; C004955:fosfestrol
Die zellvermittelte Immunität (CMI) beim Prostatakarzinom unter Einfluss von Cytonal, Estrazyt und Turisteron.