Evaluation of MUREX SUDS Toxo test.
The SUDS Toxo test (MUREX Corp., Norcross, Ga.) was compared with the indirect hemagglutination test (IHA) and the indirect fluorescent-antibody test (IFA) by examining 404 serum specimens, including 64 (15.8%) specimens with IFA titers of greater than or equal to 1:2. When SUDS was compared with IHA, sensitivity (96.4%), specificity (97.9%), and negative predictive value (99.4%) indicated that there were similar reactivities between the two tests. When an IFA titer of greater than or equal to 1:16 was considered significant and IHA and SUDS were compared with IFA, IHA was slightly less sensitive but had a higher positive predictive value than did SUDS; however, there was no statistical difference between the tests. When SUDS was compared with IFA, in which a titer of greater than or equal to 1:16 was considered significant, the high negative predictive value (100%), excellent sensitivity (100%) and specificity (98.3%), and ease of performance made SUDS an attractive alternative to IHA for screening single serum specimens for toxoplasmosis.
Moyer
N P
NP
Hygienic Laboratory, University of Iowa, Iowa City 52242.
Hudson
J D
JD
Hausler
W J
WJ
D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D003124:Colorimetry; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D006801:Humans; D007124:Immunoenzyme Techniques; D008838:Microcomputers; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D013053:Spectrophotometry; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000175:diagnosis*
D000913:Antibodies, Protozoan; D011933:Reagent Kits, Diagnostic