[Induced mutagenesis in Salmonella typhimurium AG262 strain constructed for screening the mutagens].
The Salmonella typhimurium strain AG262 has been constructed for screening of SOS-mutagens, such as UV-light and 4NQO, the Ames plasmidless tester strains of S. typhimurium being mutation-proof under the action of this class of mutagens. The strain AG262 has also been successfully used for screening of induced base pair change mutations occurring independently of cellular SOS-system of mutagenesis (MNNG, EMS, nitrofuran derivatives), and of the mutations induced by frame-shift mutagens (benzo/a/pyrene 7,12-dimethylbenzo/a/antracene ICR-191, 9AA, DDDTDP).
Liamkina
I I
II
Andreeva
I V
IV
Stepanova
N F
NF
Rusina
O Iu
OIu
Skavronskaia
A G
AG
D005798:Genes, Bacterial; D005804:Genes, Lethal; D009152:Mutagenicity Tests; D009153:Mutagens; D009154:Mutation; D013014:SOS Response, Genetics; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics*; D014466:Ultraviolet Rays
D009153:Mutagens
Indutsirovannyĭ mutagenez u shtamma Salmonella typhimurium AG262, skonstruirovannogo dlia vyiavleniia mutagennykh agentov.