title: Anaphylactic reaction to synthetic luteinizing hormone-releasing hormone.
abstract: Synthetic LH-RH is a polypeptide that is structurally identical to natural LH-RH. It has been used as a safe ovulation induction agent. A case is presented in which a patient had an anaphylactic reaction when treated with LH-RH by IV infusion. Positive skin testing confirmed this as an IgE-mediated reaction. This is the first reported case of such a reaction and stresses that careful precautions be taken when administering all medications.
authors.forename: T L
authors.initials: TL
authors.lastname: MacLeod
authors.forename: A
authors.initials: A
authors.lastname: Eisen
authors.forename: G L
authors.initials: GL
authors.lastname: Sussman
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000009:adverse effects*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy; D012882:Skin Tests
chemical_list: D007987:Gonadotropin-Releasing Hormone