Severe kidney graft rejection in combined kidney and pancreas transplantation.
With a low dose, triple drug protocol for immunosuppression, more frequent and severe rejection episodes, and lower, kidney graft survival appeared after combined kidney and pancreas transplantation than after kidney transplantation alone. With increased immunosuppression using the quadruple drug protocol that includes prophylactic ATG treatment, the results after combined transplantations improved.
Hedman
L
L
Department of Surgery I, Sahlgrens Hospital, Gothenburg, Sweden.
Frisk
B
B
Brynger
H
H
Frödin
L
L
Tufveson
G
G
Wahlberg
J
J
D000961:Antilymphocyte Serum / Q000627:therapeutic use; D001379:Azathioprine / Q000627:therapeutic use; D003524:Cyclosporins / Q000627:therapeutic use; D006084:Graft Rejection; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D007668:Kidney / Q000276:immunology; D016030:Kidney Transplantation; D016035:Pancreas Transplantation; D011239:Prednisolone / Q000627:therapeutic use
D000961:Antilymphocyte Serum; D003524:Cyclosporins; D011239:Prednisolone; D001379:Azathioprine