Alopecia areata, endocrine function, and autoantibodies in patients 16 years of age or younger.
Forty-five children with alopecia areata were prospectively studied by means of both clinical and laboratory evaluation for evidence of endocrine diseases and autoantibodies. Twenty-four percent had an abnormality as determined by one or more thyroid function studies (thyroxine, triiodothyronine, and thyroid-stimulating hormone) and/or elevation of microsomal antibody levels. In 16%, smooth muscle antibody was present, and in 4%, parietal cell antibody was present. Routine thyroid function testing is recommended for all children with alopecia areata.
Milgraum
S S
SS
Mitchell
A J
AJ
Bacon
G E
GE
Rasmussen
J E
JE
D000293:Adolescent; D000506:Alopecia Areata / Q000150:complications / Q000276:immunology* / Q000503:physiopathology; D000974:Antibodies, Antinuclear / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000150:complications; D002648:Child; D002675:Child, Preschool; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D011446:Prospective Studies; D013961:Thyroid Gland / Q000503:physiopathology*; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D014284:Triiodothyronine; D013974:Thyroxine