title: [Immunological effectiveness of secondary revaccination against tetanus performed at prolonged intervals].
abstract: After primary immunization with adsorbed DPT vaccine antitetanus immunity was retained for 9-10 years in 90.6-98.4% of children covered by this study. The second booster immunization of children against tetanus with adsorbed DT toxoid with reduced antigen content, made at an interval prolonged to 7-10 years under the conditions of lower antitoxic immunity, ensured a high level of intense antitetanus immunity. These data point to the possibility of prolonging the interval between booster immunizations to 9-10 years and reducing the number of injections and antigenic load.
authors.forename: N M
authors.initials: NM
authors.lastname: Maksimova
authors.forename: N N
authors.initials: NN
authors.lastname: Basova
authors.forename: N L
authors.initials: NL
authors.lastname: Sukhorukova
authors.forename: M P
authors.initials: MP
authors.lastname: Finkel'
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000032:analysis*; D002648:Child; D003017:Clostridium tetani / Q000276:immunology*; D004165:Diphtheria / Q000517:prevention & control; D004168:Diphtheria Toxoid / Q000008:administration & dosage / Q000276:immunology; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations / Q000008:administration & dosage / Q000276:immunology; D004341:Drug Evaluation; D006801:Humans; D007117:Immunization, Secondary / Q000379:methods*; D010567:Pertussis Vaccine / Q000008:administration & dosage / Q000276:immunology; D013742:Tetanus / Q000517:prevention & control*; D013745:Tetanus Toxoid / Q000008:administration & dosage / Q000276:immunology; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D004168:Diphtheria Toxoid; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations; D010567:Pertussis Vaccine; D013745:Tetanus Toxoid
vernacular_title: Immunologicheskaia éffektivnost' vtoroĭ revaktsinatsii protiv stolbniaka, provedennoĭ s udlinennymi intervalami.