title: Energetics of protein synthesis in mice with a major gene for growth.
abstract: The effect of the level of food intake on protein synthesis rate in carcass, liver, gastrointestinal tract (GIT) and heart, kidneys and lungs (HKL) was determined in male mice with a major gene for rapid postweaning gain (line Ch) and normal controls (line CH) at 31 d of age. In both lines of mice, food restriction lowered carcass, HKL and liver absolute protein synthesis rates (ASRs) while GIT protein ASR was not affected by food intake. As a result, whole-body protein ASR increased with increasing food intake. It was estimated that heat production from protein synthesis (HrpsE) was responsible for 8.3 and 10.8% of the maintenance energy requirement of CH and Ch mice, respectively. It was also calculated that HrpsE represents 19.4 and 18.3% of the heat increment of growth of CH and Ch mice, respectively. Energetic efficiencies of protein deposition in CH and Ch mice were 58.6 and 66.7%, respectively.
authors.affiliation: Department of Animal Science, University of California, Davis 95616.
authors.forename: J F
authors.initials: JF
authors.lastname: Bernier
authors.forename: C C
authors.initials: CC
authors.lastname: Calvert
authors.forename: R L
authors.initials: RL
authors.lastname: Baldwin
mesh_terms: D000818:Animals; D004247:DNA / Q000032:analysis; D002149:Energy Intake; D004734:Energy Metabolism; D005796:Genes; D006128:Growth; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D014176:Protein Biosynthesis
chemical_list: D004247:DNA