Genetic disorders associated with severe alopecia in children: a report of two unusual cases and a review.
Moderate to severe alopecia in children may be due to a genetic disorder. This paper reviews the heritable causes of alopecia in children and gives a detailed account of two affected unrelated children. One has alopecia universalis while the other has alopecia postulated to be due to a new disorder of genetic etiology. The article concludes that for purposes of genetic counseling and prognosis it is crucial that a correct diagnosis be made.
Feinstein
A
A
Department of Dermatology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Engelberg
S
S
Goodman
R M
RM
D000505:Alopecia / Q000235:genetics* / Q000473:pathology; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D006801:Humans; D008297:Male; D010375:Pedigree