title: Benign symmetric lipomatosis Launois-Bensaude. Report of ten cases and review of the literature.
abstract: Benign symmetric lipomatosis Launois-Bensaude is a disease rarely reported in the American literature and not mentioned in the standard English textbooks of dermatology. It seems, however, to be relatively common in Europe. Between 1981 and 1985 we examined twelve patients, and a number of case reports have been published in French and German literature. We describe ten typical cases and review the literature. The disease is characterized by massive symmetric fat deposits predominantly in the neck and shoulder girdle area. Pathogenetically, the increase in fatty tissue is assumed to result from a localized defect in catecholamine-induced lipolysis. The disease is frequently associated with alcoholism, hepatopathy, glucose intolerance, hyperuricemia, and malignant tumors of the upper airways, requiring thorough clinical evaluation of all patients. Dietary treatment and weight loss are of limited value in the management of benign symmetric lipomatosis. Surgical removal of lipomatous tissue is frequently followed by recurrence and should be restricted to decompression in patients with functional impairment.
authors.affiliation: Department of Dermatology, Ludwig-Maximilians-University, München, West Germany.
authors.forename: T
authors.initials: T
authors.lastname: Ruzicka
authors.forename: D
authors.initials: D
authors.lastname: Vieluf
authors.forename: M
authors.initials: M
authors.lastname: Landthaler
authors.forename: O
authors.initials: O
authors.lastname: Braun-Falco
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications; D005260:Female; D006801:Humans; D008068:Lipomatosis / Q000150:complications / Q000378:metabolism / Q000473:pathology; D008069:Lipomatosis, Multiple Symmetrical / Q000150:complications / Q000378:metabolism / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D009422:Nervous System Diseases / Q000209:etiology