title: Fetal karyotype following ascertainment of fetal anomalies by ultrasound.
abstract: Data pooled from contributors to a Registry for Cytogenetic Abnormalities and PKU (ReCAP) shows an unbalanced chromosome abnormality rate of 27 per cent (29 fetuses) for 107 fetuses with ultrasonically diagnosed fetal anomalies. Of the abnormal, 12 were trisomic, 6 were monosomy X and 6 were structural abnormalities, 4 were mosaics and one triploid.
authors.affiliation: Department of Medical Genetics, Indiana University School of Medicine, Indianapolis 46223.
authors.forename: C G
authors.initials: CG
authors.lastname: Palmer
authors.forename: J H
authors.initials: JH
authors.lastname: Miles
authors.forename: P N
authors.initials: PN
authors.lastname: Howard-Peebles
authors.forename: R E
authors.initials: RE
authors.lastname: Magenis
authors.forename: S
authors.initials: S
authors.lastname: Patil
authors.forename: J M
authors.initials: JM
authors.lastname: Friedman
mesh_terms: D000649:Amniocentesis; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012017:Referral and Consultation; D012729:Sex Chromosome Aberrations / Q000175:diagnosis; D014463:Ultrasonography