Anaphylactic reaction to synthetic luteinizing hormone-releasing hormone.
Synthetic LH-RH is a polypeptide that is structurally identical to natural LH-RH. It has been used as a safe ovulation induction agent. A case is presented in which a patient had an anaphylactic reaction when treated with LH-RH by IV infusion. Positive skin testing confirmed this as an IgE-mediated reaction. This is the first reported case of such a reaction and stresses that careful precautions be taken when administering all medications.
MacLeod
T L
TL
Eisen
A
A
Sussman
G L
GL
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000009:adverse effects*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy; D012882:Skin Tests
D007987:Gonadotropin-Releasing Hormone