title: Further delineation of the 3-M syndrome with review of the literature.
abstract: The 3-M syndrome is a clinically recognizable disorder characterized by prenatal and postnatal growth retardation and a spectrum of consistent minor anomalies. Intelligence seems normal. Inheritance is probably autosomal recessive, with possible expression of the mutant gene in the heterozygote. Three sibs with the 3-M syndrome are reported, together with an extensive review of the pertinent literature.
authors.affiliation: Clinical Genetics Center Utrecht, The Netherlands.
authors.forename: R C
authors.initials: RC
authors.lastname: Hennekam
authors.forename: J B
authors.initials: JB
authors.lastname: Bijlsma
authors.forename: J
authors.initials: J
authors.lastname: Spranger
mesh_terms: D001848:Bone Diseases, Developmental / Q000000981:diagnostic imaging / Q000235:genetics*; D005260:Female; D006130:Growth Disorders / Q000000981:diagnostic imaging / Q000235:genetics*; D006801:Humans; D004204:Joint Dislocations / Q000235:genetics; D008297:Male; D010375:Pedigree; D011859:Radiography; D013577:Syndrome