5-Hydroxytryptophan (5-HTP)-immunoreactive neurons in the rat brain tissue.
We demonstrated the presence of 5-hydroxytryptophan (5-HTP), the immediate precursor of serotonin (5-HT), in the rat brain tissue using a glutaraldehyde-coupled immunohistochemical technique. The immunoreactivity of 5-HTP was intensified in the colchicine-pretreated rat. The distribution of labelled cells was the same as for 5-HT-immunoreactive cells, but they were fewer in number.
Touret
M
M
Département de Médecine Expérimentale, Faculté de Médecine, Université Claude Bernard, Lyon, France.
Kitahama
K
K
Geffard
M
M
Jouvet
M
M
D006916:5-Hydroxytryptophan / Q000032:analysis*; D000818:Animals; D001921:Brain / Q000166:cytology / Q000378:metabolism; D003078:Colchicine; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008297:Male; D011903:Raphe Nuclei / Q000032:analysis* / Q000166:cytology; D051381:Rats
D006916:5-Hydroxytryptophan; D003078:Colchicine