title: Pelvic exenteration.
abstract: Exenteration, or complete excision of the pelvic viscera, is an ultra-radical surgical procedure intended for curative treatment of the patient with advanced pelvic malignancy--primary or recurrent. At the time of introduction of this procedure, enthusiasm for its use was marred by the high incidence of serious surgical morbidity and mortality, which approached the five-year survival rate. With more careful physiological and psychological selection of patients, concentration of this kind of procedure in centres familiar with its use, improved urinary conduit techniques and careful attention to covering the pelvic floor with omentum and/or synthetic materials, the morbidity and mortality rate has been significantly reduced thus making exenteration a more acceptable treatment option to a wider spectrum of patients. More sophisticated haemodynamic monitoring, both intra- and postoperatively, intravenous hyperalimentation, prophylactic antibiotics and low-dose heparin are undoubtedly important adjuncts to the improvements in surgical technique and judgment. Psychosexual 'rehabilitation' in the broadest sense must be an integral part of patient care for those undergoing exenteration and in most instances necessitates involvement of the patient's partner. Exenteration has only a very limited role in palliation and all attempts should be made to avoid this procedure when cure is clearly not a possibility.
authors.forename: K J
authors.initials: KJ
authors.lastname: Murphy
authors.forename: A D
authors.initials: AD
authors.lastname: Depetrillo
mesh_terms: D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology; D010385:Pelvic Exenteration / Q000009:adverse effects / Q000534:rehabilitation; D013518:Surgery, Plastic; D014547:Urinary Diversion; D014621:Vagina / Q000601:surgery