Numerous nerves with calcitonin gene-related peptide-like immunoreactivity innervate junctional epithelium of rats.
We found an unusually dense concentration of nerves with calcitonin gene-related peptide-like (CGRP-L) immunoreactivity in junctional epithelium of rat gingiva. Adjacent oral epithelium was only sparsely innervated. The CGRP-L innervation may affect the local inflammatory reactions, leukocyte transmigration, and serum outflow that occur in junctional epithelium, as well as having somatosensory functions.
Byers
M R
MR
Department of Anesthesiology, University of Washington, Seattle 98195.
Mecifi
K B
KB
Kimberly
C L
CL
D000818:Animals; D015740:Calcitonin Gene-Related Peptide; D004848:Epithelium / Q000032:analysis; D005260:Female; D005881:Gingiva / Q000166:cytology / Q000294:innervation*; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D009475:Neurons, Afferent / Q000032:analysis*; D009479:Neuropeptides / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D009479:Neuropeptides; D015740:Calcitonin Gene-Related Peptide