Interleukin 4/B cell stimulatory factor 1: one lymphokine, many functions.
Lymphokines are multifunctional T cell products that profoundly regulate the activation, growth, and differentiation of many cell types, most notably T cells and B cells. One of the lymphokines with the broadest range of actions is interleukin 4/B cell stimulatory factor 1. The characteristics, function, and regulation of interleukin 4 are reviewed as part of an overall discussion of the mechanism through which T cell-derived lymphokines control immune responses in vivo and in vitro.
Paul
W E
WE
Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
D000818:Animals; D000917:Antibody Formation; D001402:B-Lymphocytes / Q000276:immunology*; D015847:Interleukin-4; D007378:Interleukins / Q000494:pharmacology / Q000502:physiology*
D007378:Interleukins; D015847:Interleukin-4