[Maculopathy in typical retinitis pigmentosa apropos of 33 cases].
The authors studied 33 maculopathies in 54 patients affected by typic retinitis pigmentosa: atrophic macular degeneration 31 cases (49%); cystoïd macular oedema: 1 case (3%) and macular retraction syndrome: 1 case (3%). These results are confronted with those of the literature. Two therapeutical trials based on pathogenical hypothesis were conducted. The patient with cystoïd macular oedema was treated by Hyperbar oxygenotherapy, basing one of selves on the theory ischemia. Six other patients with atrophic foveolopathies were treated by the cyclophosphamide, according to the autoimmune theory. In the first trial, the result was positive. In the second one, the results did not permit any available conclusion.
Chachia
N
N
Service d'Ophtalmologie, Hôpital Universitaire Fattouma Bourguiba, C.H.U. de Monastir, Tunisie.
Combes
A M
AM
Romdane
K
K
Bec
P
P
D000328:Adult; D000368:Aged; D001284:Atrophy / Q000209:etiology; D002986:Clinical Trials as Topic; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D006931:Hyperbaric Oxygenation; D008266:Macula Lutea / Q000473:pathology; D008268:Macular Degeneration / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008269:Macular Edema / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012174:Retinitis Pigmentosa / Q000150:complications*
D003520:Cyclophosphamide
La maculopathie dans la rétinopathie pigmentaire typique. A propos de 33 cas.