[Atropine in intraoperative isorhythmic AV dissociation].
40 patients of the ASA groups I and II in whom intra-operatively an isorhythmic AV dissociation occurred under inhalation narcosis with halothane or enflurane, were examined in a randomized study. Within an observation period of 15 minutes the spontaneous rate of return to the sinus rhythm was 20 per cent (group A, n = 20). Intravenous administration of 0.01 mg/kg atropine sulphate produced a significantly higher rate of return of 80% within the same period. On the whole, no influence on arterial blood pressure was noted. Atropine increases the heart rate by 32%, and this is considered to be an important drawback. The possibility of influencing the AV dissociation via atropine points to the pathogenetic importance of the vagus in so far as it acts as a depressant on the sinus node.
Knüttgen
D
D
Hossmann
V
V
Doehn
M
M
D000293:Adolescent; D000328:Adult; D001285:Atropine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007431:Intraoperative Complications / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011897:Random Allocation; D013997:Time Factors
D001285:Atropine
Atropin bei intraoperativ auftretender isorhythmischer AV-Dissoziation.