Cancer genes, proto-oncogenes, and development.
The retroviral cancer genes have in a number of observations been shown to interfere with the developmental program of target cells. Here we are concerned with the interface between cancer genes/proto-oncogenes and developmental processes. Research in this field serves two purposes; to delineate key developmental controls and to identify these as targets for oncogenic agents.
Ohlsson
R I
RI
Centre for Biotechnology, Karolinska Institute, Huddinge University Hospital, Sweden.
Pfeifer-Ohlsson
S B
SB
D000818:Animals; D002454:Cell Differentiation; D002455:Cell Division; D002467:Cell Nucleus / Q000502:physiology; D004273:DNA, Neoplasm / Q000235:genetics*; D004626:Embryology; D006128:Growth; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D011519:Proto-Oncogenes
D004273:DNA, Neoplasm