Physiology of the basal ganglia and pathophysiology of Parkinson's disease.
This paper reviews current concepts concerning the anatomical organization and functions of the basal ganglia focusing mainly on the role of the basal ganglia in control of movement. Results of several studies which have been carried out on patients with Parkinson's disease are also reviewed and discussed as examples of altered normal physiological mechanisms.
Lee
R G
RG
Department of Clinical Neurosciences, Faculty of Medicine, University of Calgary, Alberta, Canada.
D000200:Action Potentials; D001479:Basal Ganglia / Q000502:physiology* / Q000503:physiopathology; D004558:Electric Stimulation; D006801:Humans; D009068:Movement; D009474:Neurons / Q000145:classification / Q000502:physiology; D010300:Parkinson Disease / Q000503:physiopathology*; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time / Q000502:physiology