title: Therapeutic considerations in childhood idiopathic thrombocytopenic purpura.
abstract: This monograph reviews the literature regarding therapy for childhood idiopathic thrombocytopenic purpura (ITP). The role and mechanism of action are discussed for corticosteroids, splenectomy, and intravenous gamma globulin. Alternative therapies with potent immunosuppressive agents are also mentioned. Guidelines for the management of children with ITP are presented.
authors.affiliation: Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
authors.forename: R
authors.initials: R
authors.lastname: Ware
authors.forename: T R
authors.initials: TR
authors.lastname: Kinney
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007116:Immunization, Passive; D007275:Injections, Intravenous; D011696:Purpura, Thrombocytopenic / Q000628:therapy*; D013156:Splenectomy
chemical_list: D000970:Antineoplastic Agents; D005938:Glucocorticoids