title: Oral ciprofloxacin as prophylaxis for optical urethrotomy.
abstract: It is known that urethral strictures predispose to bacteriuria. We studied a series of patients undergoing optical urethrotomy to see if antibiotic prophylaxis was justified. Twenty-three patients were randomised to receive either no prophylaxis or a short peri-operative course of oral ciprofloxacin. Two patients with sterile pre-operative urine and two patients with pre-operative bacteriuria given no prophylaxis had post-operative bacteriuria, whereas all patients given ciprofloxacin had sterile urine after operation. Antibiotic prophylaxis may be indicated in patients undergoing optical urethrotomy.
authors.affiliation: Department of Medical Microbiology, London Hospital.
authors.forename: D A
authors.initials: DA
authors.lastname: Murdoch
authors.forename: D F
authors.initials: DF
authors.lastname: Badenoch
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001437:Bacteriuria / Q000517:prevention & control*; D002939:Ciprofloxacin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication; D011897:Random Allocation; D014525:Urethral Stricture / Q000601:surgery*
chemical_list: D002939:Ciprofloxacin