title: [Anti-BCG antibody titers in healthy and leprous Africans. Value of an indirect immunoperoxidase test].
abstract: An immunoperoxidase reaction was used for the titration of immunoglobulins G and M antibodies to BCG in 171 leprosy patients from Dakar. The results show mean titers decreasing from lepromatous to tuberculoid cases. The antibody profiles of some clinical forms such as reverse reactions, erythema nodosum leprosum are discussed. This test associated to the Mitsuda reaction, bacteriology and histology should allow an easier classification of the borderline forms. The main advantages of the technique are simplicity, speed, low cost and the easy availability of the BCG. These qualities are essential in endemic zone.
authors.affiliation: Laboratoire de microbiologie B, C.H.U., Poitiers, France.
authors.forename: G
authors.initials: G
authors.lastname: Agius
authors.forename: E
authors.initials: E
authors.lastname: Baillargeau
authors.forename: S
authors.initials: S
authors.lastname: Ranger
authors.forename: M
authors.initials: M
authors.lastname: Castets
authors.forename: J
authors.initials: J
authors.lastname: Millan
authors.forename: A
authors.initials: A
authors.lastname: Samb
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007918:Leprosy / Q000276:immunology*; D009163:Mycobacterium bovis / Q000276:immunology*; D012016:Reference Values; D012675:Senegal
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: Titrage d'anticorps anti-BCG chez des Africains sains et lépreux. Intérêt d'un test indirect à l'immuno-peroxydase.