[Melasma in pregnancy: reduction of its appearance with the use of a broad-spectrum photoprotective agent].
65 pregnant women distributed in two groups, by a double-blind method received a placebo or a sunscreen cream (Pabafil SPF 10, with absorption range from 290 to 360 nm) for daily use on face during the second quarter of their pregnancy in summer time. In 30 patients "with optimum fulfillment" in the products application (16 with placebo and 14 with sunscreen cream) the melasma appearances were significantly lower in those with sunscreen application. In subgroups of the total number of pregnant women, with similar proportion of patients with placebo and sunscreen, the melasma appearances were significantly lower in skin types I-II, and in those that used cosmetics (versus those that did not). No differences were observed in subgroups by age, parity, and with or without history of previous melasma.
Abarca
J
J
Servicio de Dermatología, Hospital J. J. Aguirre, Santiago, Chile.
Odilla Arrollo
C
C
Blanch
S
S
Arellano
G
G
D010129:4-Aminobenzoic Acid / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D062365:Aminobenzoates / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008548:Melanosis / Q000517:prevention & control*; D010636:Phenols / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000517:prevention & control*; D011897:Random Allocation; D013473:Sunscreening Agents / Q000627:therapeutic use*; D062366:para-Aminobenzoates
D062365:Aminobenzoates; D010636:Phenols; D013473:Sunscreening Agents; D062366:para-Aminobenzoates; D010129:4-Aminobenzoic Acid
Melasma gravídico: disminución de su aparición mediante uso de un fotoprotector de amplio espectro.