title: Ticlopidine in the treatment of multiple atherosclerotic arteriopathy: a strain gauge plethysmography and Döppler spectrum analysis evaluation.
abstract: The effect of ticlopidine was compared with flunarizine in patients with iliac-femoral and/or femoral-popliteal arteriosclerotic arteriopathy accompanied by lesions of the cervical arteries of no haemodynamic significance. In the lower limbs, plethysmography (strain gauge measurements) and Döppler ultrasonography integrated by spectral analysis of the cervical arteries showed qualitative and quantitative improvements of the regional haematic flow. Side-effects were negligible which suggests that ticlopidine is useful in the treatment of multiple arteriosclerotic arteriopathy.
authors.affiliation: Department of Angiology, University of Palermo, Sicily.
authors.forename: M
authors.initials: M
authors.lastname: Cospite
authors.forename: F
authors.initials: F
authors.lastname: Ferrara
authors.forename: G
authors.initials: G
authors.lastname: Milio
authors.forename: V
authors.initials: V
authors.lastname: Scrivano
authors.forename: F
authors.initials: F
authors.lastname: Meli
mesh_terms: D000368:Aged; D001161:Arteriosclerosis / Q000188:drug therapy* / Q000503:physiopathology; D001783:Blood Flow Velocity; D005444:Flunarizine / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D010991:Plethysmography; D013988:Ticlopidine / Q000009:adverse effects / Q000627:therapeutic use*; D014463:Ultrasonography
chemical_list: D013988:Ticlopidine; D005444:Flunarizine