Combined transplantation of heart and liver from two different donors in a patient with familial type IIa hypercholesterolemia.
A 12-year-old child with terminal ischemic heart disease as a result of homozygotous familial type IIa hypercholesterolemia received an orthotopic heart transplant and, 21 days later, an orthotopic liver transplant. Six months after heart transplantation, the patient is asymptomatic and evidences normal liver function and cholesterol levels; there are no signs of heart rejection. To our knowledge, this is the first instance of two-step heart-liver transplantation with organs from different donors.
Figuera
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Ardaiz
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Martín-Júdez
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Pulpón
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LA
Pradas
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Cuervas-Mons
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Burgos
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Arcas
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Pardo
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Cienfuegos
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JA
D002648:Child; D003327:Coronary Disease / Q000209:etiology / Q000601:surgery*; D006085:Graft Survival / Q000187:drug effects; D016027:Heart Transplantation; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000150:complications*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016031:Liver Transplantation; D008297:Male; D014019:Tissue Donors
D007166:Immunosuppressive Agents