title: Cell aging in vitro: a historical perspective.
abstract: This article describes the historical background to the demonstration by Hayflick and Moorhead that human diploid cell strains in culture have limited life-spans. I suggest that the recognition of cell aging in vitro is an example from the biological sciences of a Kuhnian scientific revolution.
authors.affiliation: Imperial Cancer Research Fund Laboratories, St. Bartholomew's Hospital, London.
authors.forename: J A
authors.initials: JA
authors.lastname: Witkowksi
mesh_terms: D000818:Animals; D002470:Cell Survival; D002478:Cells, Cultured; D002642:Chick Embryo; D004171:Diploidy; D005347:Fibroblasts; D006367:HeLa Cells; D049673:History, 20th Century; D006801:Humans; D014765:Viral Vaccines
chemical_list: D014765:Viral Vaccines