Creation of atheromatous plaques in experimental animals.
Research of the dissolution of atheromatous plaques requires animal testing before any delivery system can be used on human beings. Using Flemish Giant rabbits, atheromatous plaques are created in our radiology research laboratory by a surgical air drying technique and a high cholesterol diet. Plaque development is monitored by ultrasound scanning and serial angiography.
Dreesen
R G
RG
Becker
G J
GJ
Jackson
V P
VP
D000818:Animals; D001161:Arteriosclerosis / Q000175:diagnosis / Q000000981:diagnostic imaging*; D004195:Disease Models, Animal; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D011817:Rabbits; D011859:Radiography; D014463:Ultrasonography