title: [ACPA: the first serologic marker for Wegener's granulomatosis].
abstract: The anticytoplasmatic autoantibody against intracytoplasmatic antigens of granulocytes (ACPA) was demonstratable in 23 patients in the active generalised or incomplete remission phase of Wegener's granulomatosis, but absent in 17 patients in the initial or complete remission phase. The test was negative in 900 serum samples from a control group. This autoantibody seems to be a marker of unusual specificity for Wegener's granuloma, and contributes to better assessment of activity in this disease.
authors.affiliation: Universitäts Hals-Nasen-Ohrenklinik Kiel.
authors.forename: A
authors.initials: A
authors.lastname: Beigel
authors.forename: W L
authors.initials: WL
authors.lastname: Gross
mesh_terms: D001323:Autoantibodies / Q000032:analysis*; D003593:Cytoplasm / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D006098:Granulocytes / Q000276:immunology*; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000276:immunology; D006801:Humans
chemical_list: D001323:Autoantibodies
vernacular_title: ACPA: Erster serologischer Marker für die Wegenersche Granulomatose.