title: [Changes in the total proteolytic activity and inhibitory potential of tumor and lung tissue in mice during growth and metastatic spread of malignant neoplasms].
abstract: In tumour tissue and in lungs of mice with carcinoma 3LL, melanoma B-16, adenocarcinoma 755 different changes of proteolytic and antitryptic activities have been revealed. An excessive level of the protease activity and/or a decrease of the inhibitory potential activity are the factors of decompensation of the body's protease-inhibitory system and stimulate development of metastatic process.
authors.forename: I G
authors.initials: IG
authors.lastname: Veksler
authors.forename: K N
authors.initials: KN
authors.lastname: Veremeenko
authors.forename: V N
authors.initials: VN
authors.lastname: Riabukha
authors.forename: N F
authors.initials: NF
authors.lastname: Pogorelaia
authors.forename: S I
authors.initials: SI
authors.lastname: Khaniuchenko
mesh_terms: D000818:Animals; D005260:Female; D008168:Lung / Q000201:enzymology*; D008175:Lung Neoplasms / Q000201:enzymology / Q000473:pathology / Q000556:secondary; D051379:Mice; D008810:Mice, Inbred C57BL; D009132:Muscles / Q000201:enzymology; D009362:Neoplasm Metastasis; D009374:Neoplasms, Experimental / Q000201:enzymology* / Q000473:pathology; D009928:Organ Specificity; D010447:Peptide Hydrolases / Q000378:metabolism*; D011480:Protease Inhibitors / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: D011480:Protease Inhibitors; D010447:Peptide Hydrolases
vernacular_title: Izmeneniia obshcheĭ proteoliticheskoĭ aktivnosti i ingibitornogo potentsiala tkani opukholeĭ i legkikh u mysheĭ v protsesse rosta i metastazirovaniia zlokachestvennykh novoobrazovaniĭ.