[Field trial of an immunoenzyme method using beta-lactamase as the monoclonal antibody marker for the capsular antigen of the plague microbe].
Beta-lactamase (penicillinase) has been used as a marker of monoclonal antibodies in the enzyme immunoassay made with a view to the detection of Y. pestis capsular antigen and antibodies to it. The trial of the enzyme immunoassay with the use of the beta-lactamase conjugate in laboratories and under field conditions has revealed the advantage of this assay over hemagglutination tests commonly used for this purpose.
Levi
M I
MI
Shimko
T A
TA
Temiralieva
G A
GA
D000818:Animals; D000835:Animals, Wild; D000907:Antibodies, Bacterial / Q000032:analysis; D000911:Antibodies, Monoclonal / Q000032:analysis*; D000942:Antigens, Bacterial / Q000276:immunology*; D001407:Bacillus / Q000201:enzymology; D005069:Evaluation Studies as Topic; D006386:Hemagglutination Tests; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D009500:Neutralization Tests; D010930:Plague / Q000175:diagnosis / Q000662:veterinary; D015010:Yersinia pestis / Q000276:immunology*; D001618:beta-Lactamases
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D001618:beta-Lactamases
Ispytanie v polevoĭ praktike immunofermentnogo metoda s primeneniem betalaktamazy v kachestve markera monoklonal'nykh antitel k kapsul'nomu antigneu chumnogo mikroba.