title: [Captopril in the treatment of mild cardiac insufficiency in combination with arterial hypertension].
abstract: The results of clinicoinstrumental investigations in 33 patients with coronary heart disease and coronary heart disease combined with essential hypertension complicated by stage I-II cardiac insufficiency showed that therapy with captopril at a daily dose of 25-75 mg resulted in the correction of cardiac insufficiency in 84% of the patients, with a hypotensive effect in 80%. Captopril improved myocardial contractility, decreased pressure in the pulmonary artery and total peripheral vascular resistance and produced no major side-effects.
authors.forename: L I
authors.initials: LI
authors.lastname: Ol'binskaia
authors.forename: T E
authors.initials: TE
authors.lastname: Morozova
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D002216:Captopril / Q000627:therapeutic use*; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects
chemical_list: D002216:Captopril
vernacular_title: Kaptopril v lechenii umerennoĭ serdechnoĭ nedostatochnosti i pri sochetanii ee s arterial'noĭ gipertonieĭ.