Bromocriptine therapy in cocaine withdrawal.
Twenty-four cocaine addicts who experienced withdrawal symptoms were studied for six weeks in a double-blind design. Half of the group received daily treatment with bromocriptine and the other half with placebo. Significant relief with bromocriptine was seen almost immediately and continued throughout the detoxification period. The authors speculate that the results are consistent with the "dopamine-depletion model" of cocaine withdrawal.
Giannini
A J
AJ
Northeastern Ohio Universities College of Medicine, Youngstown.
Baumgartel
P
P
DiMarzio
L R
LR
D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003042:Cocaine; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D011897:Random Allocation; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000523:psychology
D001971:Bromocriptine; D003042:Cocaine