Growth hormone in short, slowly growing children and those with Turner's syndrome.
Results of an aborted placebo controlled trial of treatment with human pituitary growth hormone in children with Turner's syndrome and short, slowly growing children are reported. One child in each group had a considerable reduction in growth rate standard deviation score while taking growth hormone. The remaining eight patients with Turner's syndrome and 10 short, slowly growing patients who received growth hormone showed mean rises in growth rate of greater than two standard deviation scores. Neither placebo group showed a mean increase in growth rate standard deviation score. These differences were significant.
Buchanan
C R
CR
Institute of Child Health, London.
Law
C M
CM
Milner
R D
RD
D000293:Adolescent; D000886:Anthropometry; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006128:Growth / Q000187:drug effects; D006130:Growth Disorders / Q000188:drug therapy*; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011897:Random Allocation; D014424:Turner Syndrome / Q000188:drug therapy*
D013006:Growth Hormone