title: Epidemiology of aerobactin production in Enterobacteriaceae.
abstract: Clinical isolates (496) of 10 different enterobacterial genera were studied for aerobactin excretion, colicin production and antibiotic resistance. In the case of Escherichia coli, the incidence of aerobactin-positive strains in 108 blood isolates (45%) was not significantly different from that corresponding to faecal sources (41%). Although colicin V production was much more frequently associated with aerobactin production than other colicins, colicin V was only produced by 26% of aerobactin excreters. Some strains were aerobactin-negative and colicin V producers. Aerobactin production seemed to be significantly associated with plasmidic antibiotic resistance. The production of the siderophore is described for the first time in Proteus, Serratia and Morganella strains.
authors.affiliation: Servicio de Microbiología, Hospital Ramón y Cajal, Madrid.
authors.forename: E
authors.initials: E
authors.lastname: Cercenado
authors.forename: F
authors.initials: F
authors.lastname: Baquero
authors.forename: A
authors.initials: A
authors.lastname: Delgado-Iribarren
authors.forename: J L
authors.initials: JL
authors.lastname: Martínez
mesh_terms: D001769:Blood / Q000382:microbiology; D003087:Colicins / Q000096:biosynthesis; D004352:Drug Resistance, Microbial; D004755:Enterobacteriaceae / Q000378:metabolism*; D004926:Escherichia coli / Q000302:isolation & purification / Q000378:metabolism; D005243:Feces / Q000382:microbiology; D006801:Humans; D006877:Hydroxamic Acids / Q000096:biosynthesis*; D014556:Urine / Q000382:microbiology
chemical_list: D003087:Colicins; D006877:Hydroxamic Acids; C031819:aerobactin