title: Precursors to regulatory peptides: their proteolytic processing.
abstract: Precursors to regulatory peptides undergo maturation processes which include proteolytic processing. The enzymes involved in this process remove the hydrophobic peptide located at the amino-terminus of the precursor. Endoprotease cleavage also occurs at single and two adjacent basic residues, this is followed by a removal of basic residues located at the C-terminus of the peptides by a carboxypeptidase-like enzyme.
authors.forename: P C
authors.initials: PC
authors.lastname: Andrews
authors.forename: K
authors.initials: K
authors.lastname: Brayton
authors.forename: J E
authors.initials: JE
authors.lastname: Dixon
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000032:analysis; D006801:Humans; D009479:Neuropeptides / Q000235:genetics*; D011499:Protein Processing, Post-Translational
chemical_list: D009479:Neuropeptides; D004247:DNA