[Current problems in the morphometry of the heart].
Cardiac morphometric data reported by different authors are difficult to compare. For linear measurements the processing methods need to be standardized and important considerations are the age-thanatogenetic features, and homogeneity of the autopsy material. An essential requirement is determination of the tissue compression coefficient. The specific volumes of structures should be measured in semithin sections. The largest disagreement among measurements have been noted for volumes of cardiac muscle cells and nuclei and for the nucleocytoplasmic ratio. The rules of stereometry are frequently violated in calculating parameters per unit sectional area. Although more than a hundred parameters have been proposed for cardiac morphometry, only two or three of them are of real diagnostic value. Standardizing morphometry of the heart, and of other organs as well, is a matter of high priority.
Gutsol
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AA
D000818:Animals; D006321:Heart / Q000033:anatomy & histology*; D006652:Histological Techniques / Q000592:standards; D006801:Humans; D009206:Myocardium / Q000473:pathology*
Sovremennnye problemy morfometrii serdtsa.