title: In vivo and in vitro granulocyte migration in patients with extrinsic and intrinsic bronchial asthma.
abstract: Sixty-five patients with atopic asthma, 54 with infectious asthma, and 30 healthy controls were evaluated by in vitro granulocyte migration and by the in vivo skin window method of Southam. Quantitative IgM, IgG, IgA, IgE serum concentrations were measured. In vivo migration of granulocytes was decreased in patients with atopic asthma and elevated levels of IgE as well as in patients with infectious asthma and elevated levels of IgG. In vivo migration of granulocytes showed significant decreases in both asthmatic groups only during asthmatic attacks.
authors.forename: R
authors.initials: R
authors.lastname: Matusiewicz
authors.forename: K
authors.initials: K
authors.lastname: Rusiecka-Matusiewicz
mesh_terms: D001249:Asthma / Q000276:immunology*; D002464:Cell Migration Inhibition; D004417:Dyspnea / Q000276:immunology; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology; D007136:Immunoglobulins / Q000032:analysis; D066298:In Vitro Techniques; D012884:Skin Window Technique
chemical_list: D007136:Immunoglobulins