The outcome of 48 renal transplantations immunosuppressed with cyclosporine-A as monotherapy.
The course of 48 consecutive cadaveric renal transplantations immunosuppressed with Cyclosporine-A (CyA) as monotherapy in 3 different doses was retrospectively analysed. CyA doses were based on clinical observations. Overall one-year graft survival was 52% and for grafts immediate diuresing 82%. A dosage schedule of 12 mg CyA/kg/day seemed to secure graft function without any side effects to the patient.
Lund Hansen
B
B
Henriksen
I
I
Rohr
N
N
Svendsen
V
V
Birkeland
S A
SA
D000328:Adult; D002908:Chronic Disease; D003524:Cyclosporins / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006085:Graft Survival / Q000187:drug effects*; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D009393:Nephritis / Q000601:surgery*
D003524:Cyclosporins