title: [Value of percutaneous blind liver biopsy in preoperative diagnosis of atresia of the extrahepatic bile ducts].
abstract: During a period of 7 years the case histories of 60 infants with direct hyperbilirubinaemia were prospectively evaluated. At presentation the majority of infants had an age below 1 month. By close clinical follow-up of all infants including the observation of acholic stools (21 infants), quantitative estimations of lipoprotein X during cholestyramine therapy (17 infants), cholescintigraphy (20 infants) and percutaneous liver biopsy (17 infants) the efficiency of the preoperative diagnostic work-up reached 96.6%. Liver biopsies were carried out selectively in only 29.3% of all infants (47.6% in infants with acholic stools and 17.9% in infants with normal stools); their efficiency in the differential diagnosis of extrahepatic biliary atresia was 88.2%.
authors.affiliation: Universitäts-Kinderklinik Graz.
authors.forename: J
authors.initials: J
authors.lastname: Deutsch
mesh_terms: D001652:Bile Ducts / Q000473:pathology; D001656:Biliary Atresia / Q000473:pathology* / Q000601:surgery; D001707:Biopsy, Needle; D002792:Cholestyramine Resin; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000473:pathology; D007567:Jaundice, Neonatal / Q000473:pathology; D008073:Lipoprotein-X / Q000097:blood; D008099:Liver / Q000473:pathology*; D008297:Male; D014463:Ultrasonography
chemical_list: D008073:Lipoprotein-X; D002792:Cholestyramine Resin
vernacular_title: Die Stellung der perkutanen Leberblindbiopsie in der präoperativen Differentialdiagnose der extrahepatischen Gallengangsatresie.