title: Treatment of urinary tract infection with norfloxacin. Analysis of cost.
abstract: Twenty-five patients with urinary tract infection were treated with norfloxacin, a fluoroquinolone antibacterial with a wide spectrum of activity for an oral agent. Of 22 patients who were evaluable, 20 had complicated urinary tract infection; infection was cured in 19 patients at one week after treatment. Optimal alternative treatments were also selected in norfloxacin's stead, based on each patient's characteristics and the results of susceptibility testing for each isolated pathogen. Direct costs for alternative treatment ranged from $7 to $970. The results indicated that for those patients with suspected or proven urinary tract infection caused by multiresistant bacteria, therapy with norfloxacin may represent a cost-effective choice.
authors.forename: C
authors.initials: C
authors.lastname: Ramirez-Ronda
authors.forename: M
authors.initials: M
authors.lastname: Colon
authors.forename: S
authors.initials: S
authors.lastname: Saavedra
authors.forename: J
authors.initials: J
authors.lastname: Sabbaj
authors.forename: M L
authors.initials: ML
authors.lastname: Corrado
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003365:Costs and Cost Analysis; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009643:Norfloxacin / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000191:economics
chemical_list: D000900:Anti-Bacterial Agents; D009643:Norfloxacin