R-plasmid RP1 promotes adhesion of gram-negative bacteria to medical prostheses and glass.
The presence of R-plasmid RP1 increased the adhesion of chemostat-grown iron- and carbon-limited Proteus mirabilis to the surfaces of various medical prostheses and to glass. Similar results were obtained with iron-limited Pseudomonas aeruginosa and anaerobically-grown Escherichia coli. Changes in the surface properties of P. mirabilis indicated that the R-plasmid-mediated increase in negative charge was one of the factors that promoted adhesion.
Onaolapo
J A
JA
Department of Pharmaceutical Sciences, Aston University, Birmingham.
el-Haffar
M I
MI
Townley
D
D
Klemperer
R M
RM
D001422:Bacterial Adhesion; D002244:Carbon / Q000378:metabolism; D005898:Glass; D006090:Gram-Negative Bacteria / Q000472:pathogenicity / Q000502:physiology*; D007501:Iron / Q000378:metabolism; D010957:Plasmids; D019736:Prostheses and Implants; D011513:Proteus mirabilis / Q000472:pathogenicity / Q000502:physiology; D013499:Surface Properties
D002244:Carbon; D007501:Iron