title: [Sonographic diagnosis of holoacardius].
abstract: In the 28th week of gestation a normal foetus and a holoacardius were diagnosed via sonography in a biamnotic monochoriatic twin pregnancy. The growth of the foetuses was observed under continuous sonographic control up to the 40th week of pregnancy. The patient delivered a healthy twin by Caesarean section and the acardius was subjected to a postmortem. Macroscopic and histological findings in the foetus, the placenta and the umbilical cords are demonstrated. The pathogenesis of the holoacardius is discussed as being due to chromosomal aberrations and foeto-foetal transfusion syndrome.
authors.affiliation: Universitäts-Frauenklinik der Universität Valencia.
authors.forename: F
authors.initials: F
authors.lastname: Bonilla-Musoles
authors.forename: A
authors.initials: A
authors.lastname: Lopez
authors.forename: G
authors.initials: G
authors.lastname: Pardo
authors.forename: J
authors.initials: J
authors.lastname: Blanes
authors.forename: J
authors.initials: J
authors.lastname: Remohi
authors.forename: C
authors.initials: C
authors.lastname: Lopez-Viveros
authors.forename: A
authors.initials: A
authors.lastname: Mayer
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000235:genetics; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D003937:Diagnosis, Differential; D004200:Diseases in Twins; D005260:Female; D005330:Fetofetal Transfusion / Q000235:genetics; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography
vernacular_title: Sonographische Diagnose eines Holoakardius.