title: [Fatal septicemias: factors of mortality. Analysis of 72 fatal cases in the series of 462 case reports collected by the Septicemia Expert System group in 1985].
abstract: During the year 1985, 462 cases of septicemia were collected by SES group; 417 observations could be exploited. 73 patients died (17.3%). The statistical analysis of epidemiological and clinical data argued to factors correlated with high mortality rate: a shock, an acute respiratory distress syndrome, a pulmonary portal of entry lead to a high mortality rate. The fatal outcome increased with the age of the patients. A documented immunodeficiency (granulopenia, cytotoxic chemotherapy...), a previous broncho-pulmonary, neurologic or cardiovascular disease were factors of risk. The pulmonary or cutaneous localisations occurring within a septicemic phase were significantly related to death. Among fatal cases of bacteremia, 25% were Staphylococci, 25% Enterobacteria, 20% Pneumococci, 7% Pseudomonas. Pseudomonas, then Pneumococcus, then Staphylococcus bacteremias looks to have a worse prognosis. The more serious cases were prescribed several antibiotics, significantly much more than the mild cases. These results are compared with the results of former series; the main prognosis factors of actual septicemia are elicited in here.
authors.affiliation: Service des Maladies Infectieuses, CHRU, Hôtel Dieu, Clermont-Ferrand.
authors.forename: J
authors.initials: J
authors.lastname: Beytout
authors.forename: E
authors.initials: E
authors.lastname: Bernard
authors.forename: J P
authors.initials: JP
authors.lastname: Stahl
authors.forename: D
authors.initials: D
authors.lastname: Blanc
authors.forename: C
authors.initials: C
authors.lastname: Beuscart
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000401:mortality*; D002648:Child; D004756:Enterobacteriaceae Infections / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000401:mortality; D011379:Prognosis; D011552:Pseudomonas Infections / Q000401:mortality; D012307:Risk Factors; D018805:Sepsis / Q000401:mortality*; D013203:Staphylococcal Infections / Q000401:mortality
vernacular_title: Les septicémies mortelles: facteurs de létalité. Analyse de 72 cas mortels dans la série de 462 observations recueillies par le groupe Système Expert Septicémie (SES) en 1985.