[Evaluation of the hypotensive effect of unilateral adrenalectomy in patients with low-renin hyperaldosteronism].
The antihypertensive effect of unilateral adrenalectomy was analyzed in 19 patients with arterial hypertension and primary hyperaldosteronism diagnosed by way comparing clinical findings, a degree of hypokalemia, activity of plasma renin and aldosterone concentration and CT data. A follow-up period after operation was 8-14 mos. Clinical and biochemical findings were compared with the results of morphological investigation of the adrenal glands and kidneys. An antihypertensive postoperative effect was observed in 12 patients: good in 6, moderate in 6, the absence of an antihypertensive effect in 7. Different forms of adrenocortical hyperplasia revealed during histomorphological investigation, endocrine nephropathy of various degree and vascular changes of hypertensive genesis in the renal parenchyma were discussed as causes of residual hypertension.
Ustinova
S E
SE
Shkhvatsabaia
I K
IK
Pokrovskiĭ
A V
AV
Kazanchian
P O
PO
Sokolova
R I
RI
D000311:Adrenal Glands / Q000473:pathology; D000315:Adrenalectomy; D000450:Aldosterone / Q000097:blood; D001794:Blood Pressure; D005069:Evaluation Studies as Topic; D005500:Follow-Up Studies; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood / Q000503:physiopathology / Q000601:surgery*; D007668:Kidney / Q000473:pathology; D011184:Postoperative Period; D012083:Renin / Q000097:blood*
D000450:Aldosterone; D012083:Renin
Otsenka gipotenzivnogo éffekta odnostoronneĭ adrenlaéktomii u bol'nykh s nizkoreninovym giperal'dosteronizmom.