Treatment of Mooren's and Mooren's-like ulcer by lamellar keratectomy: report of six eyes and literature review.
Three cases of Mooren's ulcer (four eyes) and one case of marginal corneal ulcer associated with relapsing polychondritis (two eyes) are presented with decrease in ocular inflammation following extensive lamellar keratectomy or lamellar keratoplasty. Tissue adhesive was needed in two cases to maintain ocular integrity. The procedure may work by the removal of a corneal antigenic stimulus to a self-perpetrating auto-immune phenomenon that causes corneal melting. More cases are needed to evaluate the therapeutic efficacy of lamellar keratectomy for Mooren's and Mooren's-like corneal ulcers.
Martin
N F
NF
Wilmer Institute, Johns Hopkins Hospital, Baltimore, Maryland 21205.
Stark
W J
WJ
Maumenee
A E
AE
D000368:Aged; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D003320:Corneal Ulcer / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011081:Polychondritis, Relapsing / Q000150:complications