title: Variables influencing the outcome following orthotopic liver transplantation.
abstract: Seventy-two patients who underwent orthotopic liver transplantation (OLT) were studied to identify perioperative variables that would predict survival and intraoperative blood loss. Survival and intraoperative blood loss were not affected by encephalopathy, length of donor liver ischemia, or any of the preoperative laboratory values studied. Survival was significantly decreased in patients requiring postoperative dialysis (41%) and in patients who had severe rejection requiring retransplantation (33%). Intraoperative blood loss was significantly greater in patients over 50 years of age (11.6 blood volumes) and patients with biliary atresia (8.7 blood volumes). These results may aid in choosing future recipients for orthotopic liver transplantation and in anticipating the postoperative support needed.
authors.affiliation: Department of Surgery, UCLA, School of Medicine.
authors.forename: J J
authors.initials: JJ
authors.lastname: Brems
authors.forename: J R
authors.initials: JR
authors.lastname: Hiatt
authors.forename: J O
authors.initials: JO
authors.lastname: Colonna
authors.forename: G
authors.initials: G
authors.lastname: el-Khoury
authors.forename: W J
authors.initials: WJ
authors.lastname: Quiñones
authors.forename: K P
authors.initials: KP
authors.lastname: Ramming
authors.forename: S
authors.initials: S
authors.lastname: Ziomek
authors.forename: R W
authors.initials: RW
authors.lastname: Busuttil
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001656:Biliary Atresia / Q000601:surgery; D001810:Blood Volume; D002648:Child; D002675:Child, Preschool; D005260:Female; D006084:Graft Rejection; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007223:Infant; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D011167:Portacaval Shunt, Surgical / Q000009:adverse effects; D011183:Postoperative Complications; D011184:Postoperative Period; D006435:Renal Dialysis; D012086:Reoperation; D012189:Retrospective Studies