[Histostereological analysis of the parenchyma and stroma of the atrophied myocardium in alimentary starvation].
The sexually mature Wistar rats were placed in separated cages and totally deprived of food (but allowed water ad libitum) for 2, 4 and 8 days. Tissue stereological analysis of myocardium included the determination of volume and surface densities of cardiomyocytes, volume density of stroma, volume and surface densities of capillaries and interstitial cells, volume-to-volume and surface-to-volume ratios of the basic components of parenchyma and stroma. The correlation and information analyses of the stereological parameters were carried out. It was shown that the development of myocardial atrophy (a decrease in heart weight and cardiomyocyte diameter) was accompanied by decreasing the volume density of parenchyma and increasing the volume density of stroma. A decrease in the surface of the exchange between the cardiomyocytes and microcirculatory bed was also revealed in alimentary starvation.
Nepomniashchikh
L M
LM
Kolesnikova
L V
LV
Tumanov
V P
VP
Nepomniashchikh
G I
GI
D000818:Animals; D001284:Atrophy / Q000473:pathology; D006652:Histological Techniques; D008297:Male; D008854:Microscopy, Electron; D009206:Myocardium / Q000473:pathology*; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D013217:Starvation / Q000473:pathology*; D013997:Time Factors
Gistostereologicheskiĭ analiz parenkhimy i stromy atrofiruiushchegosia miokarda pri alimentarnom golodanii.