[Malignant neoplastic pathology in patients given a kidney transplant].
The incidence of malignant neoplasms in patients subjected to pharmacological immunosuppression following kidney transplantation is higher than that observed in the control population at large. In our unit, in a study population of 451 patients undergoing a total of 462 kidney transplants over the period from 1968 to 1986, four malignant neoplasms (0.9%) were observed in 3/369 (0.8%) patients treated with azathioprine (1 ovarian papilliferous cystoadenoma, 1 embryonal carcinoma of the testicle and 1 Kaposi's sarcoma) and in 1/93 (1.1%) patients treated with cyclosporin (1 Kaposi's sarcoma). The neoplasm was successfully controlled only in the first case after bilateral extended adnexectomy.
Prati
G F
GF
Regione Veneto-ULSS 25, Centro Ospedaliero di Borgo Trento.
Recchia
G
G
Dean
P
P
Boschiero
L
L
Faccincani
L
L
Muolo
A
A
D001379:Azathioprine / Q000009:adverse effects; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016030:Kidney Transplantation; D008223:Lymphoma / Q000209:etiology; D009369:Neoplasms / Q000209:etiology*; D012514:Sarcoma, Kaposi / Q000209:etiology
D001379:Azathioprine
La patologia neoplastica maligna nel paziente sottoposto a trapianto renale.