[The Su-polysaccharide skin test in lung cancer].
Skin testing with intradermally injected Su-Polysaccharide (extracted from Su strain Streptococcus bacteria) was performed in 41 cases of lung cancer. Su-polysaccharide skin test results were correlated, to some extent, with the patient's age, clinical stage and performance status and showed a similar trend to the simultaneously performed PPD skin test. These results suggested the potential usefulness of Su-Polysaccharide skin test results as one of the parameters of immunological status of patients with lung cancer. It was also demonstrated that skin reaction to Su-Polysaccharide was increased specifically after OK-432 immunotherapy and was well correlated with the prognosis of the disease. The Su-Polysaccharide skin test was thus considered to be a useful parameter for monitoring the immune response to OK-432 immunotherapy in lung cancer and also one of the parameters of prognostic value.
Harada
J
J
Horiguchi
T
T
Oki
K
K
Miyamoto
H
H
Osada
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001688:Biological Products / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010844:Picibanil / Q000627:therapeutic use*; D011135:Polysaccharides, Bacterial / Q000276:immunology; D012882:Skin Tests; D013297:Streptococcus pyogenes; D014374:Tuberculin Test
D001688:Biological Products; D011135:Polysaccharides, Bacterial; D010844:Picibanil