Release of plasminogen activator by batroxobin.
In the isolated perfused pig ear, batroxobin caused a dose-dependent increase in the release of plasminogen activator. The activator-releasing effect required the presence of the active enzyme. The activator released was of the tissue-type.
Klöcking
H P
HP
Hoffmann
A
A
Markwardt
F
F
D000818:Animals; D012103:Batroxobin / Q000494:pharmacology*; D001808:Blood Vessels / Q000187:drug effects / Q000378:metabolism; D005342:Fibrinolysis / Q000187:drug effects; D066298:In Vitro Techniques; D010447:Peptide Hydrolases / Q000494:pharmacology*; D010477:Perfusion; D010960:Plasminogen Activators / Q000378:metabolism*; D013552:Swine
D010447:Peptide Hydrolases; D012103:Batroxobin; D010960:Plasminogen Activators