title: Systemic noninflammatory vasculopathy with prominent CNS involvement--a case report.
abstract: This is a case report of a thirty-seven-year-old man with systemic noninflammatory vasculopathy who developed a slowly progressive dementia with multiple sites of stroke. Cerebral angiography revealed abnormal terminal vasculature with beading and occlusions. Brain biopsy confirmed a noninflammatory vascular pathology. We have also reviewed the world literature relevant to this clinicopathologic entity and have discussed its relationship to thromboangiitis obliterans cerebri.
authors.affiliation: Department of Neurology, State University of New York, Upstate Medical Center, Syracuse.
authors.forename: M
authors.initials: M
authors.lastname: Molaie
authors.forename: G H
authors.initials: GH
authors.lastname: Collins
mesh_terms: D000328:Adult; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000209:etiology; D003704:Dementia / Q000209:etiology*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013919:Thromboangiitis Obliterans / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014652:Vascular Diseases / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging