Theoretical modelling of protein synthesis.
This article provides an overview of the use of mathematical and computer modelling in furthering the understanding of protein synthesis. In particular, we discuss issues such as the nature of the rate limiting step(s), error rates, tRNA-codon adaptation, codon bias, attenuation control, and problems of selection and error corrections, focussing on their theoretical treatment.
von Heijne
G
G
Department of Theoretical Physics, Royal Institute of Technology, Stockholm, Sweden.
Blomberg
C
C
Liljenström
H
H
D003062:Codon; D003198:Computer Simulation; D008954:Models, Biological; D009690:Nucleic Acid Conformation; D014176:Protein Biosynthesis
D003062:Codon