A comparison of histamine and methacholine bronchial challenges using the DeVilbiss 646 nebulizer and the Rosenthal-French dosimeter.
We have compared bronchial challenge with both histamine and methacholine for the tidal breathing method and dosimeter method, using the DeVilbiss 646 nebulizer, in 18 patients with asthma. There was a significant difference between the PC20 FEV1 but not the PD20 FEV1 when either agonist was administered by the different techniques but not by the same method.
Bennett
J B
JB
Academic Department of Respiratory Medicine, St Bartholomew's Hospital, West Smithfield, London.
Davies
R J
RJ
D000328:Adult; D001249:Asthma / Q000175:diagnosis*; D001985:Bronchial Provocation Tests / Q000295:instrumentation / Q000379:methods; D002986:Clinical Trials as Topic; D005260:Female; D005541:Forced Expiratory Volume; D006632:Histamine; D006801:Humans; D008297:Male; D016210:Methacholine Chloride; D008688:Methacholine Compounds; D008875:Middle Aged
D008688:Methacholine Compounds; D016210:Methacholine Chloride; D006632:Histamine