title: Failure of patent aorto-renal grafts to cure hypertension in renin positive patients.
abstract: Correction of renal artery stenosis in a hypertensive patient does not always result in cure of the hypertension. In a follow-up on 127 patients operated on for renovascular hypertension over a 24-year period 32 patients with favourable preoperative factors, unilateral disease, normal renal parenchyma and a positive renal vein renin ratio were studied. 20/32 were regarded as cured with a BP of less than 140/90 and 12/32 were regarded as unsuccessful with a BP, although lessened, higher than 140/90. Hypotensive medication was required in 10/12 in the latter group and was still required in 8/20 of the former. The cure rate of less than 2/3rd is lower than most reports in the literature. The possible causes of the discrepancy are discussed.
authors.affiliation: Department of Surgery, University of Sydney, Australia.
authors.forename: J
authors.initials: J
authors.lastname: May
authors.forename: R
authors.initials: R
authors.lastname: Sheil
authors.forename: J
authors.initials: J
authors.lastname: Harris
authors.forename: J
authors.initials: J
authors.lastname: Horvath
mesh_terms: D000328:Adult; D001012:Aorta, Abdominal / Q000601:surgery*; D001794:Blood Pressure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D012008:Recurrence; D012074:Remission Induction; D012082:Renal Veins / Q000601:surgery*; D012083:Renin / Q000097:blood*; D013997:Time Factors
chemical_list: D012083:Renin