Computer-assisted predictions of signal peptidase processing sites.
Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.
Folz
R J
RJ
Gordon
J I
JI
D000596:Amino Acids / Q000032:analysis; D010450:Endopeptidases / Q000032:analysis*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008565:Membrane Proteins; D010449:Peptide Mapping / Q000379:methods; D012697:Serine Endopeptidases; D012984:Software
D000596:Amino Acids; D008565:Membrane Proteins; D010450:Endopeptidases; D012697:Serine Endopeptidases; C026515:type I signal peptidase