title: Partial structure of an insulin-sensitive glycophospholipid.
abstract: The structure of a glycophospholipid, which has been involved in insulin action, has been investigated using H35 cells and rat liver membranes. The present evidence indicates that this molecule contains a phosphatidyl-chiro-inositol moiety, glycosidically linked to a non-N-acetylated glucosamine. In addition, the polar head group of the lipid contains galactose, probably four residues, and a total number of three phosphates.
authors.forename: J M
authors.initials: JM
authors.lastname: Mato
authors.forename: K L
authors.initials: KL
authors.lastname: Kelly
authors.forename: A
authors.initials: A
authors.lastname: Abler
authors.forename: L
authors.initials: L
authors.lastname: Jarett
authors.forename: B E
authors.initials: BE
authors.lastname: Corkey
authors.forename: J A
authors.initials: JA
authors.lastname: Cashel
authors.forename: D
authors.initials: D
authors.lastname: Zopf
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002460:Cell Line; D002851:Chromatography, High Pressure Liquid; D005944:Glucosamine / Q000031:analogs & derivatives* / Q000032:analysis; D007328:Insulin / Q000494:pharmacology*; D008114:Liver Neoplasms, Experimental / Q000032:analysis; D010716:Phosphatidylinositols / Q000032:analysis*; D010738:Type C Phospholipases / Q000378:metabolism
chemical_list: D007328:Insulin; D010716:Phosphatidylinositols; D010738:Type C Phospholipases; D005944:Glucosamine