title: GABA-like immunoreactivity in the chick vestibular end organs.
abstract: gamma-Aminobutyric acid (GABA)-like immunoreactivity in the chick vestibular endorgans was examined using an antiserum against GABA coupled with glutaraldehyde to bovine serum albumin. GABA-like immunoreactivity was confined to the cytoplasm of the hair cells in both cristae and maculae. GABA-like immunoreactive cells were evenly distributed throughout the sensory epithelia, and no difference existed between type I and type II hair cells. The results provide evidence that GABA-like immunoreactivity is localized to sensory cells and raises the possibility that GABA may serve as an afferent neurotransmitter in the chick vestibular end organs.
authors.affiliation: Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, Houston, TX 77030.
authors.forename: S
authors.initials: S
authors.lastname: Usami
authors.forename: M
authors.initials: M
authors.lastname: Igarashi
authors.forename: G C
authors.initials: GC
authors.lastname: Thompson
mesh_terms: D000110:Acetylcholinesterase / Q000032:analysis; D000818:Animals; D002645:Chickens; D006198:Hair Cells, Auditory / Q000032:analysis* / Q000294:innervation; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D009411:Nerve Endings / Q000032:analysis*; D014722:Vestibule, Labyrinth / Q000032:analysis / Q000294:innervation*; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
chemical_list: D005680:gamma-Aminobutyric Acid; D000110:Acetylcholinesterase