[Effect of trypsin and kallikrein (andecalin) on the activity of proteolytic enzymes and their inhibitors in acute experimental pancreatitis].
Intramuscular administration of trypsin and kallikrein (andecaline) into rats contributed to more favourable development of acute traumatic pancreatitis. Trypsin and andecaline prevented the activation of proteinases in blood serum and pancreas and promoted an increase in content of trypsin inhibitor in blood serum. The proteinases efficiency appears to depend on elevation of general resistance of the organism to the trauma.
Kolenda
Iu V
IuV
Vansovich
V E
VE
Vovchuk
S V
SV
Levitskiĭ
A P
AP
D000208:Acute Disease; D000818:Animals; D004789:Enzyme Activation; D006868:Hydrolysis; D007610:Kallikreins / Q000627:therapeutic use*; D010195:Pancreatitis / Q000188:drug therapy / Q000201:enzymology*; D010447:Peptide Hydrolases / Q000097:blood*; D011480:Protease Inhibitors / Q000097:blood*; D051381:Rats; D011919:Rats, Inbred Strains; D014357:Trypsin / Q000627:therapeutic use*
D011480:Protease Inhibitors; D010447:Peptide Hydrolases; D007610:Kallikreins; D014357:Trypsin
Vliianie tripsina i kallikreina (andekalina) na aktivnost' proteoliticheskikh fermentov i ikh ingibitorov pri ostrom éksperimental'nom pankreatite.