title: Liver alcohol dehydrogenase.
abstract: The article deals with the structure and function of liver alcohol dehydrogenase and reviews mainly literature published after 1979, i.e., summarizes progress made in the field since Klinman presented her review on alcohol dehydrogenases. The emphasis will be on high-resolution crystallographic data, results obtained with metal-substituted enzyme derivatives, and on the mechanism and pH dependence of the catalytic reaction.
authors.forename: G
authors.initials: G
authors.lastname: Pettersson
mesh_terms: D000426:Alcohol Dehydrogenase / Q000502:physiology*; D000818:Animals; D001665:Binding Sites; D003067:Coenzymes / Q000378:metabolism; D003461:Crystallography; D004791:Enzyme Inhibitors / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes / Q000502:physiology; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D046911:Macromolecular Substances; D008670:Metals / Q000378:metabolism; D008956:Models, Chemical; D008958:Models, Molecular; D009243:NAD / Q000378:metabolism; D011487:Protein Conformation; D013329:Structure-Activity Relationship
chemical_list: D003067:Coenzymes; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D046911:Macromolecular Substances; D008670:Metals; D009243:NAD; D000426:Alcohol Dehydrogenase