Recurrence risk in the Angelman ("happy puppet") syndrome.
We report on two sibs with Angelman "happy puppet" syndrome. Out of 48 families reported in the literature, this is only the fourth family with affected sibs. A review of the literature shows a low but not negligible recurrence risk. Different explanations for this are discussed.
Willems
P J
PJ
Department of Pediatrics, University Hospital, Groningen, The Netherlands.
Dijkstra
I
I
Brouwer
O F
OF
Smit
G P
GP
D002648:Child; D002675:Child, Preschool; D005260:Female; D005684:Gait; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D007845:Laughter; D008297:Male; D009069:Movement Disorders / Q000235:genetics; D011378:Prognathism / Q000235:genetics; D012008:Recurrence; D012306:Risk; D013064:Speech Disorders / Q000235:genetics*; D013577:Syndrome