title: The histopathology of rectosigmoid biopsies from adults with bloody diarrhea due to verotoxin-producing Escherichia coli.
abstract: The histopathology of rectosigmoid biopsies from 20 patients with bloody diarrhea resulting from verotoxin-producing Escherichia coli infection is reported. The biopsies displayed a range of appearances, from normal to mild, nonspecific inflammation to acute infectious-type colitis. Surface-adherent or invasive bacteria were not identified. The morphologic features of infectious colitis and the absence of bacteria suggest that verotoxin may be responsible for the pathologic changes.
authors.forename: J K
authors.initials: JK
authors.lastname: Kelly
authors.forename: C H
authors.initials: CH
authors.lastname: Pai
authors.forename: I H
authors.initials: IH
authors.lastname: Jadusingh
authors.forename: M L
authors.initials: ML
authors.lastname: Macinnis
authors.forename: E A
authors.initials: EA
authors.lastname: Shaffer
authors.forename: N B
authors.initials: NB
authors.lastname: Hershfield
mesh_terms: D001427:Bacterial Toxins / Q000302:isolation & purification*; D001706:Biopsy; D003092:Colitis / Q000209:etiology / Q000473:pathology*; D012809:Colon, Sigmoid / Q000473:pathology*; D003967:Diarrhea / Q000209:etiology*; D004926:Escherichia coli / Q000378:metabolism; D004927:Escherichia coli Infections / Q000473:pathology*; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D012007:Rectum / Q000473:pathology*; D022622:Shiga Toxin 1
chemical_list: D001427:Bacterial Toxins; D022622:Shiga Toxin 1