title: 5-Hydroxytryptophan (5-HTP)-immunoreactive neurons in the rat brain tissue.
abstract: We demonstrated the presence of 5-hydroxytryptophan (5-HTP), the immediate precursor of serotonin (5-HT), in the rat brain tissue using a glutaraldehyde-coupled immunohistochemical technique. The immunoreactivity of 5-HTP was intensified in the colchicine-pretreated rat. The distribution of labelled cells was the same as for 5-HT-immunoreactive cells, but they were fewer in number.
authors.affiliation: Département de Médecine Expérimentale, Faculté de Médecine, Université Claude Bernard, Lyon, France.
authors.forename: M
authors.initials: M
authors.lastname: Touret
authors.forename: K
authors.initials: K
authors.lastname: Kitahama
authors.forename: M
authors.initials: M
authors.lastname: Geffard
authors.forename: M
authors.initials: M
authors.lastname: Jouvet
mesh_terms: D006916:5-Hydroxytryptophan / Q000032:analysis*; D000818:Animals; D001921:Brain / Q000166:cytology / Q000378:metabolism; D003078:Colchicine; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008297:Male; D011903:Raphe Nuclei / Q000032:analysis* / Q000166:cytology; D051381:Rats
chemical_list: D006916:5-Hydroxytryptophan; D003078:Colchicine