[Monobloc lamellar autokeratoplasty (MLAK) and corneal cicatrization. Apropos of a comparative trial in a control group and a group treated with a L-cystine and pyridoxine hydrochloride combination].
In pterygium cure, one piece lamellar corneo-conjunctival autokeratoplasty allows to perform a reproducible corneal injury in human clinic, and thus, to study the epithelial healing. The authors describe a comparative test on 2 groups of 18 subjects each, receiving in this blind study, either classical post-operative treatment (witness group), or in addition to this treatment: L-Cystine and Pyridoxine Chlorhydrate. Two tests are analysed: the duration of epithelial healing in one day (negative fluorescein test) and post operative "well being" (estimated on the intensity of photophobia, tears and pain). Statistical analysis (non parameter tests) display a significant difference in favor of the group treated by Cystine B 6.
Rivaud
C
C
Negrel
A D
AD
D000328:Adult; D002986:Clinical Trials as Topic; D003228:Conjunctiva / Q000637:transplantation*; D003315:Cornea / Q000187:drug effects; D016039:Corneal Transplantation; D003553:Cystine / Q000008:administration & dosage* / Q000494:pharmacology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008722:Methods; D011182:Postoperative Care; D011625:Pterygium / Q000601:surgery*; D011736:Pyridoxine / Q000008:administration & dosage* / Q000494:pharmacology; D011897:Random Allocation; D014945:Wound Healing / Q000187:drug effects*
D003553:Cystine; D011736:Pyridoxine
Autokératoplastie lamellaire monobloc (AKLM) et cicatrisation cornéenne. A propos d'un essai comparatif d'un groupe témoin et d'un groupe traité par l'association de L-Cystine et Chlorhydrate de Pyridoxine.