title: DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes.
abstract: We sequenced the 5'-coding region of the human c-src gene, exons 2 through 5, corresponding to one-third of the human c-src protein consisting of 536 amino acids. Sequence analysis of the src type of protein kinases revealed that the amino-terminal region encoded by exon 2 contains sequences specific for the src proteins and raised the possibility that this region is involved in the recognition of a src-specific substrate(s) or receptor(s).
authors.forename: A
authors.initials: A
authors.lastname: Tanaka
authors.forename: C P
authors.initials: CP
authors.lastname: Gibbs
authors.forename: R R
authors.initials: RR
authors.lastname: Arthur
authors.forename: S K
authors.initials: SK
authors.lastname: Anderson
authors.forename: H J
authors.initials: HJ
authors.lastname: Kung
authors.forename: D J
authors.initials: DJ
authors.lastname: Fujita
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002645:Chickens; D005796:Genes; D006801:Humans; D007438:Introns; D009857:Oncogenes; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D012326:RNA Splicing; D012689:Sequence Homology, Nucleic Acid
chemical_list: D011518:Proto-Oncogene Proteins; D011505:Protein-Tyrosine Kinases