Recurrent membranoproliferative glomerulonephritis type 1 in successive renal transplants.
We report a man who developed renal failure due to membranoproliferative glomerulonephritis (MPGN) type 1 which recurred in two cadaveric kidney transplants. This is the third such case in the literature. Nephrotic syndrome developed within 1 month following transplantation and histologic evidence of disease recurrence was documented in both kidneys 2 months after transplantation. Both grafts failed within 18 months. Factors which determine disease recurrence remain obscure.
Glicklich
D
D
Matas
A J
AJ
Sablay
L B
LB
Senitzer
D
D
Tellis
V A
VA
Soberman
R
R
Veith
F J
FJ
D000328:Adult; D005921:Glomerulonephritis / Q000209:etiology / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000473:pathology*; D016030:Kidney Transplantation; D008297:Male; D008854:Microscopy, Electron; D012008:Recurrence; D012086:Reoperation