Delayed-type allergy against various insulin preparations including human semisynthetic insulin.
The authors present a patient with delayed-type allergy against insulin preparations of different species including highly purified monocomponent insulin and human semisynthetic insulin. Positive results for cutaneous delayed-type hypersensitivity and for lymphocyte blastogenesis suggested a type IV immunopathogenic reaction. Intradermal tests performed with various components of insulin preparations revealed delayed-type allergy to insulins of different species (bovine, porcine and human) but not to any of the other components.
Würzburger
M I
MI
Prelević
G M
GM
Despotović
N
N
Vucković
S
S
Brkić
S D
SD
Bozović
M
M
Nastić-Mirić
D
D
D004342:Drug Hypersensitivity / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology*; D007328:Insulin / Q000009:adverse effects*; D008875:Middle Aged; D012882:Skin Tests
D007328:Insulin