[Treatment of advanced cancer of the ovary using intensive chemotherapy with autograft of bone marrow. From a case, discussion and review of the literature].
A case of treatment of an advanced ovarian adenocarcinoma (Stage IIIc of the FIGO) is reported. The patient underwent a maximal tumor reduction followed with polychemotherapy. After this treatment, a "second look" laparotomy shows an incomplete remission. An intensive chemotherapy with abdomini-pelvic radiotherapy and protection of medullary toxicity by a bone marrow autograft is performed, with a satisfactory result, without relapse, 16 months after this treatment (or 25 months after the first laparotomy). A review of the literature concerning the treatment to be undertaken following the "second look" operation, is briefly exposed. Reasons which led the authors to perform an autograft and mostly the conditions under which this treatment may be offered, are then presented.
Nores
J M
JM
Dalayeun
J
J
Otmezguine
Y
Y
Le Douarin
L A
LA
Folgoas
C
C
Nenna
A
A
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D003536:Cystadenocarcinoma / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*
Le traitement du cancer de l'ovaire évolué par chimiothérapie intensive avec autogreffe de moelle osseuse. A partir d'un cas, discussion et revue de la littérature.