Familial occurrence of intracranial aneurysms in childhood: a case report and review of the literature.
This report describes three individuals belonging to one family, who were affected with ruptured intracranial aneurysms (IAs) at a rather young age, 4, 15 and 23 years respectively. Familial IAs at this young age have not been described before. The evidence for a developmental, eventually inherited origin of familial IA in childhood is discussed with reference to the low occurrence of non-familial IA in childhood, IA-features in non-familial cases (localisation, multiplicity, size) and the association with (other) congenital malformations in the 0-5 years group.
ter Berg
H W
HW
Department of Child Neurology, University Hospital Utrecht, The Netherlands.
Bijlsma
J B
JB
Willemse
J
J
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002675:Child, Preschool; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000453:epidemiology / Q000235:genetics* / Q000601:surgery; D008297:Male; D010375:Pedigree; D012422:Rupture, Spontaneous; D012737:Sex Factors