Serum antibodies to Escherichia coli in breast-fed and bottle-fed infants.
Titers of antibody against Escherichia coli in human milk and in the sera of 11 breast-fed infants, 6 bottle-fed infants and 9 infants in the post-weaning period were measured by the passive hemagglutination method. High antibody titers were observed in human milk in the first 4 days after parturition, but the titer decreased rapidly thereafter. None of the healthy, breast-fed infants had detectable serum antibodies, while a breast-fed infant with a perianal E. coli abscess had antibodies. On the other hand, 4 of the 6 bottle-fed infants and all of the 9 infants in the post-weaning period had antibodies. The significance of these results was discussed.
Ogura
H
H
Department of Pediatrics, Kochi Medical School, Japan.
D000038:Abscess / Q000276:immunology; D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D001942:Breast Feeding; D002648:Child; D004926:Escherichia coli / Q000276:immunology*; D004927:Escherichia coli Infections / Q000276:immunology; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007112:Immunity, Maternally-Acquired; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D008895:Milk, Human / Q000276:immunology
D000907:Antibodies, Bacterial