title: Effects of bone graft and electrical stimulation on the strength of healing bony defects in dogs.
abstract: Autogenous cancellous bone graft alone or in combination with electrical stimulation is commonly employed yet there exists no conclusive data that the strength of the healing defect is actually modified. The authors examined three groups of paired canine femurs that were torsion tested to failure. Group I (in vitro): an intact femur was compared to a standard defect; Group II (in vivo): a defect alone was compared to a defect plus graft killed at eight weeks; Group III (in vivo): a defect plus graft was compared to a defect graft plus Osteostim (BGS Medical Corp., Milwaukee, Wisconsin) implantable stimulator killed at eight weeks. In Group I the defect decreased the average strength 45% (p = 0.005); in Group II the grafted defect decreased the strength 20% (p = 0.121); in Group III the defect graft plus electrical stimulation increased strength 4% (p = 0.669). At eight weeks, bone grafting, alone or with electrical stimulation did not statistically increase the torsional strength of the healing bony defect.
authors.forename: R W
authors.initials: RW
authors.lastname: Lindsey
authors.forename: J
authors.initials: J
authors.lastname: Grobman
authors.forename: R E
authors.initials: RE
authors.lastname: Leggon
authors.forename: M
authors.initials: M
authors.lastname: Panjabi
authors.forename: G E
authors.initials: GE
authors.lastname: Friedlaender
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001847:Bone Diseases / Q000503:physiopathology / Q000628:therapy*; D016025:Bone Transplantation; D001842:Bone and Bones / Q000502:physiology; D004285:Dogs; D004599:Electric Stimulation Therapy; D010012:Osteogenesis