Disorders of adrenal steroidogenesis.
This article reviews the processes of normal adrenal function, including the three main classes of hormones. From there it describes reduced or absent enzyme activity in the stages of steroid synthesis, and proceeds to outline the enzyme deficiency responsible for the clinical effects that manifest themselves in characteristic metabolic disturbances.
Drucker
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D000302:Adrenal Cortex / Q000378:metabolism; D000312:Adrenal Hyperplasia, Congenital / Q000201:enzymology / Q000378:metabolism*; D005938:Glucocorticoids / Q000096:biosynthesis; D012739:Gonadal Steroid Hormones / Q000096:biosynthesis; D006801:Humans; D008297:Male; D008901:Mineralocorticoids / Q000096:biosynthesis; D013250:Steroid Hydroxylases / Q000172:deficiency; D013256:Steroids / Q000096:biosynthesis*
D005938:Glucocorticoids; D012739:Gonadal Steroid Hormones; D008901:Mineralocorticoids; D013256:Steroids; D013250:Steroid Hydroxylases