title: Small-intestinal factors promote encystation of Giardia lamblia in vitro.
abstract: Bile salts and fatty acids stimulated differentiation of cultured Giardia lamblia trophozoites into water-resistant cysts at the slightly alkaline pH of the small intestinal lumen. Maximum encystation occurred at pH 7.8. Thus, specific small-intestinal factors may influence encystation in vivo as well as in vitro.
authors.affiliation: Department of Pathology, University of California San Diego 92103.
authors.forename: F D
authors.initials: FD
authors.lastname: Gillin
authors.forename: D S
authors.initials: DS
authors.lastname: Reiner
authors.forename: S E
authors.initials: SE
authors.lastname: Boucher
mesh_terms: D000818:Animals; D001647:Bile Acids and Salts / Q000502:physiology; D005227:Fatty Acids / Q000502:physiology; D005872:Giardia / Q000166:cytology*; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000469:parasitology*
chemical_list: D001647:Bile Acids and Salts; D005227:Fatty Acids