title: Erosion of psoriatic plaques after chronic methotrexate administration.
abstract: A 43-year-old white man developed a shallow erosion of a psoriatic plaque after chronic administration of methotrexate. This unusual cutaneous sign may be the first sign of methotrexate toxicity.
authors.affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina.
authors.forename: D L
authors.initials: DL
authors.lastname: Kaplan
authors.forename: E A
authors.initials: EA
authors.lastname: Olsen
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology; D012883:Skin Ulcer / Q000139:chemically induced* / Q000473:pathology
chemical_list: D008727:Methotrexate