Is there too little or too much cholinergic activity in amyotrophic lateral sclerosis?
It is suggested that amyotrophic lateral sclerosis may be caused by a succinyl choline-like molecule which binds tightly to acetyl choline receptors. The formation of such a molecule might be catalysed by heavy metals.
Lundkvist
S
S
Skytteohigen UD, Gavle, Sweden.
D000690:Amyotrophic Lateral Sclerosis / Q000209:etiology / Q000378:metabolism*; D002384:Catalysis; D006801:Humans; D008670:Metals / Q000378:metabolism; D011950:Receptors, Cholinergic / Q000378:metabolism*; D013390:Succinylcholine / Q000378:metabolism
D008670:Metals; D011950:Receptors, Cholinergic; D013390:Succinylcholine