Disseminated Mycobacterium haemophilum infection in two patients with the acquired immunodeficiency syndrome.
In two patients with the acquired immunodeficiency syndrome (AIDS), multiple erythematous cutaneous lesions developed, revealing acid-fast organisms on Fite's stain. Initial culture results on the first patient were negative; however, repeat cultures on hemin-enriched media were positive for Mycobacterium haemophilum. Despite antimycobacterial therapy, lesions persisted until the patients' death. M. haemophilum should be a diagnostic consideration when smears of peripheral (especially skin) lesions from AIDS patients show acid-fast organisms. Cultures in such patients should be done with iron hemin- or ferric ammonium citrate-enriched media.
Rogers
P L
PL
Clinical Center, and National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.
Walker
R E
RE
Lane
H C
HC
Witebsky
F G
FG
Kovacs
J A
JA
Parrillo
J E
JE
Masur
H
H
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D006801:Humans; D008297:Male; D009164:Mycobacterium Infections / Q000209:etiology*; D009165:Mycobacterium Infections, Nontuberculous / Q000209:etiology*; D009170:Nontuberculous Mycobacteria / Q000302:isolation & purification; D012874:Skin Diseases, Infectious / Q000209:etiology*