title: Massive intraocular hemorrhage associated with anticoagulation and age-related macular degeneration.
abstract: The clinicopathologic correlation of three eyes with massive intraocular hemorrhage in patients receiving anticoagulant therapy is reported. All three patients were apparently predisposed because of antecedent disciform macular degeneration. The hemorrhage arose from the extrachoroidal neovascular vessels within the disciform lesions and caused rupture of the retinal pigment epithelium with massive intraocular hemorrhage. Because of the risk of vision-threatening intraocular hemorrhage, patients with exudative macular degeneration requiring anticoagulant therapy should be managed by both ophthalmologists and internists.
authors.affiliation: Jules Stein Eye Institute, UCLA School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Lewis
authors.forename: S H
authors.initials: SH
authors.lastname: Sloan
authors.forename: R Y
authors.initials: RY
authors.lastname: Foos
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000150:complications*; D008297:Male; D012166:Retinal Hemorrhage / Q000139:chemically induced* / Q000473:pathology
chemical_list: D000925:Anticoagulants