Antibacterial activity of recombinant murine beta interferon.
Recombinant murine beta interferon was protective and therapeutic for mice against Listeria monocytogenes infection in vivo. The recombinant murine beta interferon caused enhanced H2O2 release by macrophages in vivo, but not in vitro.
Fujiki
T
T
Department of Biochemistry, Shimane Medical University, Izumo, Japan.
Tanaka
A
A
D000818:Animals; D006861:Hydrogen Peroxide / Q000378:metabolism; D007167:Immunotherapy; D007370:Interferon Type I / Q000627:therapeutic use*; D008088:Listeriosis / Q000517:prevention & control / Q000628:therapy*; D008099:Liver / Q000382:microbiology; D008262:Macrophage Activation; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D011994:Recombinant Proteins / Q000627:therapeutic use; D013154:Spleen / Q000382:microbiology
D007370:Interferon Type I; D011994:Recombinant Proteins; D006861:Hydrogen Peroxide