title: [Seasonal fluctuations in the activity of stromal precursor cells of human bone marrow].
abstract: The results of the cloning of fibroblastic colony-forming units (CFU-F) from the bone marrow of normal sites of the spongy bones were analysed in 250 orthopaedic patients. It has been shown that the activity of CFU-F was changing during a year. The number of negative results of CFU-F's cloning were 33%, 60% and 50% in March, April and October respectively. The absolute values of CFU-F cloning were lower in March and April than in other months. The seasonal changes in the activity of CFU-F in human bone marrow should be taken into consideration when studying the physiology and pathology of the bone and hemopoietic system, and in clinical practice.
authors.forename: V S
authors.initials: VS
authors.lastname: Astakhova
mesh_terms: D001854:Bone Marrow Cells; D002999:Clone Cells / Q000166:cytology; D003114:Colony-Forming Units Assay; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D009985:Orthopedics; D012621:Seasons
vernacular_title: Sezonnye kolebaniia aktivnosti stromal'nykh kletok-predshestvennikov kostnogo mozga cheloveka.