title: Sensitization studies in the guinea pig with the active ingredients of Euxyl K 400.
abstract: The preservative Euxyl K 400 consists of the 2 active ingredients, 2-phenoxyethanol and 1,2-dibromo-2,4-dicyanobutane. Sensitization studies with the guinea pig maximization test were performed with these substances, but no sensitizing capacity was demonstrated in the case of either compound.
authors.affiliation: Department of Occupational Dermatology, University Hospital, Lund, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Bruze
authors.forename: B
authors.initials: B
authors.lastname: Gruvberger
authors.forename: G
authors.initials: G
authors.lastname: Agrup
mesh_terms: D000818:Animals; D003877:Dermatitis, Contact / Q000209:etiology*; D005026:Ethylene Glycols / Q000633:toxicity*; D005260:Female; D006168:Guinea Pigs; D009570:Nitriles / Q000633:toxicity*; D010592:Pharmaceutic Aids / Q000633:toxicity*; D011310:Preservatives, Pharmaceutical / Q000633:toxicity*; D012882:Skin Tests
chemical_list: D005026:Ethylene Glycols; D009570:Nitriles; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; C005398:phenoxyethanol; C039411:1,2-dibromo-2,4-dicyanobutane