title: Predictive value of abnormal sperm morphology in in vitro fertilization.
abstract: In patients with acceptable sperm count and motility, two patterns of abnormal morphology, judged with strict criteria, were identified and described. Patients with less than 4% normal forms and less than 30% morphology index (summation of normal and slightly amorphous forms) had a fertilization rate of 7.6% of the oocytes (P pattern, poor prognosis). Patients with normal morphology between 4 and 14% had a significantly better fertilization rate of 63.9% of the oocytes (P less than 0.0001). Cases with greater than 14% normal forms fertilized within the normal range for the laboratory. By evaluating sperm morphology with the proposed strict criteria, its predictive value in in vitro fertilization is enhanced.
authors.affiliation: Infertility Clinic, Tygerberg Hospital, University of Stellenbosch, Parow, South Africa.
authors.forename: T F
authors.initials: TF
authors.lastname: Kruger
authors.forename: A A
authors.initials: AA
authors.lastname: Acosta
authors.forename: K F
authors.initials: KF
authors.lastname: Simmons
authors.forename: R J
authors.initials: RJ
authors.lastname: Swanson
authors.forename: J F
authors.initials: JF
authors.lastname: Matta
authors.forename: S
authors.initials: S
authors.lastname: Oehninger
mesh_terms: D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D009865:Oocytes / Q000166:cytology; D010062:Ovulation Induction; D011379:Prognosis; D013081:Sperm Motility; D013094:Spermatozoa / Q000002:abnormalities* / Q000166:cytology