title: Bone marrow necrosis in acute lymphoblastic leukaemia.
abstract: Bone marrow necrosis, an uncommon finding in acute lymphoblastic leukaemia, has previously been regarded as a poor prognostic feature. It has been associated with difficulty in establishing the diagnosis, a low rate of remission as well as short remission duration. We report a case of bone marrow necrosis in a girl with acute lymphoblastic leukaemia and good prognostic features who attained complete remission uneventfully and will discuss previous reports of this association in the literature.
authors.affiliation: Haematology Department, Western Infirmary, Glasgow.
authors.forename: H W
authors.initials: HW
authors.lastname: Habboush
authors.forename: I M
authors.initials: IM
authors.lastname: Hann
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D009336:Necrosis; D011379:Prognosis; D012074:Remission Induction