title: Sequential development of chronic lymphocytic leukemia in a patient with polycythemia vera.
abstract: A patient with a seven-year history of polycythemia vera treated by repeated phlebotomies and intermittent busulfan administration developed gradually lymphocytosis accompanied by thrombocytopenia in peripheral blood and in the bone marrow. A marked pathological monoclonal proliferation of the B-cell population was detected. The sequential development of chronic lymphocytic leukemia in the patient with polycythemia vera could be considered as a coincidence because there is no reliable explanation of this event at present.
authors.affiliation: Cancer Research Institute of the Slovak Academy of Sciences, Bratislava, Czechoslovakia.
authors.forename: I
authors.initials: I
authors.lastname: Koza
authors.forename: O
authors.initials: O
authors.lastname: Babusíková
mesh_terms: D000954:Antigens, Surface / Q000032:analysis; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000473:pathology; D007963:Leukocytes, Mononuclear / Q000473:pathology; D008875:Middle Aged; D011087:Polycythemia Vera / Q000150:complications* / Q000473:pathology
chemical_list: D000954:Antigens, Surface