Renal and urinary tract abnormalities associated with chromosome aberrations.
The frequency of malformations of the kidney and urinary tract is much higher in patients with chromosome aberrations than in the general population. Sixty to 100% of "cat-eye" syndrome, 60 to 80% of Turner, 75% of trisomy 8, 33 to 70% of trisomy 18, 50 to 60% of trisomy 13, and over 50% of triploidy and tetraploidy patients may have such abnormalities. Renal and urinary tract malformations should be looked for in all patients with chromosome aberrations. Moreover, a chromosome study is indicated in any fetus with an ultrasonographic evidence of urinary tract abnormality.
Barakat
A Y
AY
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.
Butler
M G
MG
D002869:Chromosome Aberrations; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities*; D008297:Male; D009006:Monosomy; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014314:Trisomy; D014551:Urinary Tract / Q000002:abnormalities*