title: In utero bladder diversion--problems with patient selection.
abstract: Based upon the concept that an obstruction-maldevelopment sequence is reversible after diversion, it has been suggested that the fetus with a bladder outlet obstruction is a potential candidate for in utero intervention. We report an infant who had both renal and pulmonary dysplasia at birth despite a technically successful diversion at 22 weeks' gestation. The poor outcome suggests that the organ damage either occurs so early that it precludes corrective surgery, or that the maldevelopment is not the result of obstruction, but rather a primary mesodermal defect.
authors.affiliation: Department of Obstetrics and Gynecology, University of Iowa, Iowa City.
authors.forename: C
authors.initials: C
authors.lastname: Weiner
authors.forename: R
authors.initials: R
authors.lastname: Williamson
authors.forename: S M
authors.initials: SM
authors.lastname: Bonsib
authors.forename: A
authors.initials: A
authors.lastname: Erenberg
authors.forename: K
authors.initials: K
authors.lastname: Pringle
authors.forename: W
authors.initials: W
authors.lastname: Smith
authors.forename: M
authors.initials: M
authors.lastname: Abu-Yousef
mesh_terms: D000005:Abdomen; D000015:Abnormalities, Multiple; D003560:Cysts / Q000150:complications; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities; D008168:Lung / Q000002:abnormalities; D008297:Male; D011247:Pregnancy; D014463:Ultrasonography; D014521:Urethra / Q000002:abnormalities; D001748:Urinary Bladder Neck Obstruction / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D014547:Urinary Diversion