title: Merkel cell tumor of the thigh.
abstract: This case of a Merkel cell carcinoma is unusual due to the occurrence of the tumor on the thigh; most Merkel cell tumors have been found on the sun-exposed region of the head and neck. Histologically, the nodule was composed of sheets of uniform, poorly differentiated cells with a high nuclear to cytoplasmic ratio. Electron microscopy revealed perinuclear filaments, scattered dense core granules, and complex, interdigitating processes within cytoplasmic membranes. Treatment consisted of surgical excision of the tumor with a wide margin.
authors.affiliation: Stanford University School of Medicine, Department of Dermatology, California.
authors.forename: M L
authors.initials: ML
authors.lastname: Lindae
authors.forename: B J
authors.initials: BJ
authors.lastname: Nickoloff
authors.forename: I
authors.initials: I
authors.lastname: Greene
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D013848:Thigh