Transfer of aged Pu to cattle grazing on a contaminated environment.
Estimates are obtained of the fraction of ingested or inhaled 239+240Pu transferred to blood and tissues of a reproducing herd of beef cattle, individuals of which grazed within fenced enclosures for up to 1064 d under natural conditions with no supplemental feeding at an arid site contaminated 16 y previously with Pu oxide. The estimated (geometric mean [GM]) fraction of Pu transferred from the gastrointestinal tract to blood serum was about 5 x 10(-6) (geometric standard error [GSE] = 1.4) with an approximate upper bound of about 2 x 10(-5). These results are in reasonable agreement with the value of 1 x 10(-5) recommended for human radiation protection purposes by the International Commission on Radiological Protection (ICRP) for insoluble Pu oxides that are free of very small particles. Also, results from a laboratory study by Stanley (St75), in which large doses of 238Pu were orally administered daily to dairy cattle for 19 consecutive days, suggest that aged 239+240Pu at this arid grazing site may not be more biologically available to blood serum than fresh 239+240Pu oxide. The estimated fractions of 239+240Pu transferred from blood serum to tissues of adult grazing cattle were: femur (3.2 X 10(-2), 1.8; GM, GSE), vertebra (1.4 X 10(-1), 1.6), liver (2.3 X 10(-1), 2.0), muscle (1.3 X 10(-1), 1.9), female gonads (7.9 X 10(-5), 1.5), and kidney (1.4 X 10(-3), 1.7). The blood-to-tissue fractional transfers for cattle initially exposed in utero were greater than those exposed only as adults by a factor of about 4 for femur (statistically significant) and of about 2 for other tissues (not significant). The estimated (GM) fraction of inhaled Pu initially deposited in the pulmonary lung was 0.34 (GSE = 1.3) for adults and 0.15 (GSE = 1.3) for cattle initially exposed in utero (a statistically significant difference), which may be compared with the expected fraction of 0.11 at the study site using the ICRP lung model for humans.
Gilbert
R O
RO
Computational Sciences Department, Pacific Northwest Laboratory, Richland, WA 99352.
Engel
D W
DW
Smith
D D
DD
Shinn
J H
JH
Anspaugh
L R
LR
Eisele
G R
GR
D000280:Administration, Inhalation; D000284:Administration, Oral; D000398:Air Pollution, Radioactive; D000818:Animals; D002417:Cattle / Q000097:blood / Q000378:metabolism*; D005260:Female; D005333:Fetus / Q000378:metabolism; D005507:Food Contamination, Radioactive; D008297:Male; D011005:Plutonium / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D011247:Pregnancy; D013997:Time Factors; D014018:Tissue Distribution
D011005:Plutonium