9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl) derivatives of adenine and 3-deazaadenine: potent inhibitors of bovine liver S-adenosylhomocysteine hydrolase.
Narayanan
S R
SR
Department of Pharmaceutical Chemistry, University of Kansas, Lawrence 66045.
Keller
B T
BT
Borcherding
D R
DR
Scholtz
S A
SA
Borchardt
R T
RT
D000225:Adenine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000241:Adenosine / Q000031:analogs & derivatives / Q000494:pharmacology; D000243:Adenosine Deaminase / Q000378:metabolism; D043383:Adenosylhomocysteinase; D000818:Animals; D002417:Cattle; D006867:Hydrolases / Q000037:antagonists & inhibitors*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D009243:NAD / Q000032:analysis
D009243:NAD; C055133:3-deazaadenine; C031096:neplanocin A; D006867:Hydrolases; D043383:Adenosylhomocysteinase; D000243:Adenosine Deaminase; D000225:Adenine; D000241:Adenosine