title: Anovaginal and rectovaginal fistulas in Crohn's disease.
abstract: Between 1957 and 1985, 886 women with Crohn's disease and an intact distal large bowel were seen at St. Mark's Hospital. Ninety of these patients developed a fistula between the vagina and anus or rectum at an average age of 34 years. The track of the fistula was clearly documented in 80 patients and was extrasphincteric or suprasphincteric in 36, transsphincteric in 42 (high 13, low 29), and superficial in two. Of the 90 patients, 12 (13 percent) were managed throughout without recourse to surgery. Twelve (13 percent) had the fistula laid open or drainage of an abscess as the only surgery. Twelve (13 percent) underwent repair of the fistula and, of these, eight remain symptomatically cured. One has had further symptoms but no surgery while three later underwent proctectomy for rectal disease. In eight patients the colon was removed and the rectum defunctioned and in 34 the rectum was excised as the initial surgery after development of the fistula. The remaining 12 (13 percent) underwent later proctectomy for rectal disease or failed conservative management of the fistula. Extensive colonic involvement, rectal disease, or associated anal lesions were the main reasons for rectal excision in 38 patients. In only ten was the rectovaginal fistula a prominent indication for proctectomy. As medical treatment, repair, or other local surgery were successful in one third of the patients, these options should always be considered in the first instance.
authors.affiliation: St. Mark's Hospital, London, United Kingdom.
authors.forename: A G
authors.initials: AG
authors.lastname: Radcliffe
authors.forename: J K
authors.initials: JK
authors.lastname: Ritchie
authors.forename: P R
authors.initials: PR
authors.lastname: Hawley
authors.forename: J E
authors.initials: JE
authors.lastname: Lennard-Jones
authors.forename: J M
authors.initials: JM
authors.lastname: Northover
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003082:Colectomy; D003125:Colostomy; D003424:Crohn Disease / Q000150:complications*; D004322:Drainage; D005260:Female; D006801:Humans; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care; D012006:Rectovaginal Fistula / Q000145:classification / Q000209:etiology / Q000628:therapy*; D012007:Rectum / Q000601:surgery