[Comparative effectiveness of chrysanol and auranofin in rheumatoid arthritis].
A randomized study of 46 patients with classic and definite rheumatoid arthritis on chrysotherapy (25 patients--auranofin orally and 21--allochrysine intramuscularly) showed a therapeutic effect of both drugs. Allochrysine turned out more effective, it was not abandoned in any patients as a result of its inefficacy. However as compared to allochrysine auranofin was slightly better tolerated.
Atakhodzhaeva
Z A
ZA
Sigidin
Ia A
IaA
D000284:Administration, Oral; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001310:Auranofin / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004112:Dimercaprol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004361:Drug Tolerance; D005260:Female; D006046:Gold / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008667:Metalloproteins / Q000008:administration & dosage / Q000627:therapeutic use*; D050607:Organogold Compounds; D009942:Organometallic Compounds; D020005:Propanols; D011897:Random Allocation; D013438:Sulfhydryl Compounds
D000894:Anti-Inflammatory Agents, Non-Steroidal; D008667:Metalloproteins; D050607:Organogold Compounds; D009942:Organometallic Compounds; D020005:Propanols; D013438:Sulfhydryl Compounds; D004112:Dimercaprol; D001310:Auranofin; D006046:Gold; C013394:aurotioprol
Sravnitel'naia éffektivnost' krizanola i auranofina pri revmatoidnom artrite.