title: Single-scan stereotactic tumor biopsy and brachytherapy.
abstract: Stereotactic tumor biopsy and brachytherapy catheter implantation can be accomplished with targets derived from computed axial tomography and magnetic resonance scans. Computer manipulation of image data allows both diagnostic and therapeutic procedures to be carried out from a single set of scan slices. This eliminates the need for repeat scanning as part of the surgical procedure. Microcomputer technology is sufficiently advanced to handle the images and graphics necessary for stereotactic neurosurgery. A system based on the IBM PC/AT designed for this purpose uses readily available graphics software and custom-designed imaging programs. Direct loading of computed axial or magnetic resonance scan images from magnetic tape can be accomplished. Determination of points, contours and volumes in three-dimensional space allows intraoperative alignment of image data and patient landmarks within the stereotactic head frame using pattern recognition overlays. Three-axis scaling for magnification correction along with rotational and linear data transformations provide the basis for single-scan stereotaxis. Interactive computer graphics integrate image, patient and frame coordinates for target determination. This method eliminates the need to design and fabricate nonmagnetic or radiolucent scanner-compatible devices.
authors.affiliation: Ohio State University Hospital, Columbus.
authors.forename: J H
authors.initials: JH
authors.lastname: Goodman
authors.forename: J R
authors.initials: JR
authors.lastname: Davis
authors.forename: R A
authors.initials: RA
authors.lastname: Gabauer
authors.forename: C
authors.initials: C
authors.lastname: Kanellitsas
mesh_terms: D001706:Biopsy / Q000379:methods; D001918:Brachytherapy / Q000379:methods*; D001932:Brain Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D013238:Stereotaxic Techniques