Psychoneurogenic stress influences upon retention of an inhibitory avoidance response in the rat.
Hormones and peptides involved in the response of an organism to stress play a modulating role in learning and memory processes. We studied whether psychoneurogenic stressors such as sound stimulation or novelty influence retention of an inhibitory avoidance response. An impairing effect on retention was observed when these stressors were applied shortly after the acquisition trial, but not after a 3-h delay. However, sound stimulation and novelty applied shortly before the retention test may facilitate retention behavior. It is suggested that the effect of psychoneurogenic stressors on retention behavior may be linked to influences on consolidation and retrieval processes mediated through the neurohumoral response of the organism to stress.
Meere
M
M
Department of Psychobiology, Cajal Institute, CSIC, Velázquez, Madrid, Spain.
Borrell
J
J
D000161:Acoustic Stimulation; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D007266:Inhibition, Psychological / Q000502:physiology; D008297:Male; D008568:Memory / Q000502:physiology*; D010913:Pituitary-Adrenal System / Q000503:physiopathology; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time; D012153:Retention, Psychology / Q000502:physiology*; D013312:Stress, Physiological / Q000503:physiopathology* / Q000523:psychology