title: [Fibrinolytic activity of natural variants of Bacillus mesentericus].
abstract: The natural variability of the ability to synthesize proteinases by Bacillus mesentericus 64 was studied. The population of this strain was shown to be heterogeneous. Three types of variants (S, M and P) differed in the morphology of their colonies and in the culture characteristics from the typical colonies of the parent strain. The caseinolytic activity of the M variant was three times as high as that of the parent strain, and it also had an elevated fibrinolytic activity and a high rate of blood thrombolysis in experiments in vitro. The rate of proteinase synthesis correlated with the morphological types of sporogenic bacteria.
authors.forename: A A
authors.initials: AA
authors.lastname: Imshenetskiĭ
authors.forename: G V
authors.initials: GV
authors.lastname: Cherkesova
authors.forename: I D
authors.initials: ID
authors.lastname: Kasatkina
authors.forename: N G
authors.initials: NG
authors.lastname: Nesterova
authors.forename: Z S
authors.initials: ZS
authors.lastname: Fetisova
mesh_terms: D001407:Bacillus / Q000201:enzymology*; D002364:Caseins / Q000378:metabolism; D003470:Culture Media / Q000378:metabolism; D005337:Fibrin / Q000378:metabolism; D005342:Fibrinolysis / Q000187:drug effects*; D014644:Genetic Variation; D010447:Peptide Hydrolases / Q000096:biosynthesis / Q000494:pharmacology*
chemical_list: D002364:Caseins; D003470:Culture Media; D005337:Fibrin; D010447:Peptide Hydrolases
vernacular_title: O fibrinoliticheskoĭ aktivnosti estestvennykh variantov Bacillus mesentericus.