title: Prenatal diagnosis of del(11)(p13p15).
abstract: Prenatal diagnosis of del(11)(p13p15) was made on cultured amniotic fluid cells and confirmed on fetal skin fibroblasts after termination of pregnancy. Both irides appeared behind schedule in development by 2-3 weeks in reference to the gestational age of the fetus. It is suggested that the aniridia of the aniridia--Wilms tumour association is due to developmental arrest. Confirmation of this complex is difficult at mid-gestation without critical pathological study of the eyes.
authors.affiliation: Department of Pathology, Toronto General Hospital, Canada.
authors.forename: R J
authors.initials: RJ
authors.lastname: Stern
authors.forename: W S
authors.initials: WS
authors.lastname: Hunter
authors.forename: T
authors.initials: T
authors.lastname: Moross
authors.forename: H A
authors.initials: HA
authors.lastname: Gardner
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000166:cytology; D002872:Chromosome Deletion; D002880:Chromosomes, Human, Pair 11; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D007498:Iris / Q000002:abnormalities; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods