title: Quinidine-induced allergic granulomatous angiitis: an unusual cause of acute renal failure.
abstract: A case of systemic allergic-type vasculitis after the administration of quinidine and digoxin is described. The renal biopsy findings are unique in that they describe an arteritis with eosinophilic infiltration and non-caseating granulomata. We believe quinidine is the antigen that was responsible for the reported findings.
authors.affiliation: Westmead Hospital, NSW.
authors.forename: J
authors.initials: J
authors.lastname: Quin
authors.forename: M
authors.initials: M
authors.lastname: Adamski
authors.forename: K
authors.initials: K
authors.lastname: Howlin
authors.forename: W
authors.initials: W
authors.lastname: Jones
authors.forename: P
authors.initials: P
authors.lastname: O'Neill
authors.forename: G
authors.initials: G
authors.lastname: Stewart
authors.forename: A
authors.initials: A
authors.lastname: Young
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D004077:Digoxin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004802:Eosinophilia / Q000139:chemically induced*; D006099:Granuloma / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011802:Quinidine / Q000009:adverse effects*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced*
chemical_list: D004077:Digoxin; D011802:Quinidine