Malignant hemangiopericytoma in three kindred members of one family.
Three cases of malignant hemangiopericytoma in one family are reported. To our knowledge familial occurrence of malignant hemangiopericytoma has not been described before. Two of these lesions occurred in the head and neck region and one case presented as an intraabdominal tumor. Consanguinity of the parents seems to be likely, suggesting an autosomal recessive mode of inheritance in our family, whereas the similarity in age of onset in these three patients was apparent.
Plukker
J T
JT
Department of Surgery, University Hospital Groningen, The Netherlands.
Koops
H S
HS
Molenaar
I
I
Vermey
A
A
ten Kate
L P
LP
Oldhoff
J
J
D000328:Adult; D005260:Female; D006393:Hemangiopericytoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D010375:Pedigree; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery