title: [Staging in Hodgkin's lymphoma. Exploratory laparotomy with splenectomy].
abstract: In the present paper, 66 Studies on exploratory laparotomy with splenectomy in Hodgkin's lymphoma from Western Europe and the USA are presented in tables. This statistical compilation on 7183 laparotomies shows that the spleen was involved in 39.9% (2685 out of 6900 cases investigated), the liver in only 7.7% (446 out of 5789) and the abdominal lymph nodes were involved in 30.3% (1389 out of 4578) of the cases. Altogether, laparotomy with splenectomy led to a change in staging in 33% of the patients (1892 out of 5745). In the period from 1970 to 1986, 123 patients with Hodgkin's lymphoma were laparotomized (and also splenectomied apart from one exception) at the Surgical Division, University of Göttingen. The patients comprised 52 cases in the context of primary staging and 71 cases in the context of secondary staging. In 43 cases (35.2%) the spleen was affected, in seven cases (5.7%) the liver was affected, and there was combination with spleen involvement in each case. Infiltration of abdominal lymph nodes was shown in 38.2% (26/68). Exploratory laparotomy led to a change in stage in 46 cases (37.1%) comprising 28 improvements and 18 deteriorations. Before laparotomy, 15 patients were in stage I, 29 in stage II, 44 in stage III and 21 in stage IV. After pathological staging, 14 were in stage I, 40 were in stage II, 47 were in stage II and 19 were in stage IV. Out of the 14 patients who could not be assigned to any stage before the operation, 11 could be definitively staged afterwards. In addition, lymphography was performed in 103 patients, liver and spleen scintigraphy in 51 patients, sonography in 30 patients and computer tomography in 22 patients. In the re-examination of the lymph node situation in the retroperitoneal space, lymphography attained a specificity of 48% and a sensitivity of 71.4% with a positive prediction precision of 35.7% and a negative prediction precision of 88.8%.
authors.affiliation: Chirurgischen Klinik, Universität Göttingen.
authors.forename: C
authors.initials: C
authors.lastname: Wilke
authors.forename: H J
authors.initials: HJ
authors.lastname: Peiper
authors.forename: E
authors.initials: E
authors.lastname: Dühmke
authors.forename: U
authors.initials: U
authors.lastname: Fischer
authors.forename: A
authors.initials: A
authors.lastname: Gregl
authors.forename: H
authors.initials: H
authors.lastname: Zinn
authors.forename: G
authors.initials: G
authors.lastname: Nagel
mesh_terms: D006689:Hodgkin Disease / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008099:Liver / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D013156:Splenectomy
vernacular_title: Staging beim Hodgkin-Lymphom. Explorative Laparotomie mit Splenektomie.