title: Is localization of acute myocardial infarction time related?
abstract: A total of 1744 patients admitted to the ICCU with acute myocardial infarction (AMI) were studied in 1462 consecutive days (1982-1986). The aim of the study was to check whether the localization of the AMI was time related. Anterior (anterolateral) (AW) (n = 834) versus inferior-posterior (inferolateral) (IPW) (n = 823) AMI were compared: a third group with isolated lateral wall (LW) AMI (n = 87) was included in the study. Significant differences between monthly AMI localizations were registered, but no rhythmicity (monthly, seasonal) was found. A small absolute prevalence of AW localizations was found in all four seasons, but monthly differences made those differences not statistically significant. Some significant correlation (p less than 0.01) was found between AW AMI domination and daily geomagnetic activity (GMA level I-IV). Only on days with low (quiet) levels of GMA were there more IPW AMIs. Adverse relationship was seen with LW AMI, relatively benign in AMI, was adversely correlated with GMA level (p less than 0.01). Differences in AW/IPW and left/right coronary artery autonomic receptors distribution and flow regulation and/or changes in cardiovascular homeostasis/coagulation, aggregation, viscosity, microcirculation, and so on connected with AMI expansion may be involved in these differences of AMI localization.
authors.affiliation: Toor Heart Institute, Beilinson Medical Center, Petah Tikva, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Stoupel
authors.forename: M
authors.initials: M
authors.lastname: Shimshoni
authors.forename: J
authors.initials: J
authors.lastname: Agmon
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction; D012621:Seasons