title: Combined modality treatment of peritoneal mesotheliomas.
abstract: Five patients with peritoneal mesothelioma were treated with a multimodality approach consisting of debulking surgery, ip chemotherapy, and whole-abdomen irradiation. Chemotherapy included cisplatin and doxorubicin; radiation was given by an open-field technique. Three patients remain disease free at 46, 60, and 61 months after diagnosis. This treatment approach may serve as a model for common tumors characterized by abdominal carcinomatosis.
authors.affiliation: Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA.
authors.forename: G S
authors.initials: GS
authors.lastname: Lederman
authors.forename: A
authors.initials: A
authors.lastname: Recht
authors.forename: T
authors.initials: T
authors.lastname: Herman
authors.forename: R
authors.initials: R
authors.lastname: Osteen
authors.forename: J
authors.initials: J
authors.lastname: Corson
authors.forename: K H
authors.initials: KH
authors.lastname: Antman
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000628:therapy*; D010534:Peritoneal Neoplasms / Q000628:therapy*