title: [Regional intra-arterial chemotherapy with Dacarbazine in isolated liver metastases of a malignant melanoma].
abstract: A 58-year-old woman underwent regional intra-arterial chemotherapy for hepatic metastases of a malignant melanoma, because at the time no other organ metastasis was demonstrable. Dacarbazine was injected as a bolus on five successive days, four weeks apart, after which there were several days of fever and the urinary melanogen test became positive. At first the patient clearly improved and was again able to walk. But four months after the start of treatment she died in a hepatic coma.
authors.affiliation: Hautklinik, Universität Mainz.
authors.forename: M
authors.initials: M
authors.lastname: Böckers
authors.forename: E
authors.initials: E
authors.lastname: Keller
authors.forename: K
authors.initials: K
authors.lastname: Bork
mesh_terms: D010478:Chemotherapy, Cancer, Regional Perfusion; D003606:Dacarbazine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008545:Melanoma / Q000188:drug therapy* / Q000556:secondary; D008875:Middle Aged; D012878:Skin Neoplasms
chemical_list: D003606:Dacarbazine
vernacular_title: Regionale intraarterielle Chemotherapie mit Dacarbazin bei isolierten Lebermetastasen eines malignen Melanoms.