Carcinoma in situ of the upper aerodigestive tract. Incidence, time trends, and follow-up in Rochester, Minnesota, 1935-1984.
Epidemiologic analyses of carcinoma in situ (CIS) of the upper aerodigestive tract (UAT) are virtually nonexistent. The current investigation summarizes the total UAT CIS experience of a white, middle class community from 1935 through 1984. Average annual incidence rates varied between genders (3.1 per 100,000 person-years for males versus 0.6 per 100,000 person-years for females), and increased from 1.5 to 3.1 lesions per 100,000 person-years between 1935 and 1964, and 1965 and 1984. Virgin CIS lesions represented 13% of all UAT carcinomas and the vermilion borders of the lips accounted for 42% of all UAT CIS cases. Age-specific incidence rates for males demonstrated a continuous increase with increasing age to 40.5 per 100,000 for males older than 75 years. A clinicopathologic analysis of these lesions is provided.
Bouquot
J E
JE
Department of Oral Pathology, West Virginia University School of Dentistry, Morgantown 26506.
Kurland
L T
LT
Weiland
L H
LH
D000328:Adult; D000367:Age Factors; D000368:Aged; D002278:Carcinoma in Situ / Q000453:epidemiology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000453:epidemiology*; D006801:Humans; D008048:Lip Neoplasms / Q000453:epidemiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D008910:Minnesota