title: Status of calcium influx in cell cycle of S. cerevisiae.
abstract: The transport of calcium was assayed in exponentially growing and G1 arrested temperature sensitive cdc mutants of Saccharomyces cerevisiae. There was no statistically significant difference in the rate of Ca2+ influx in cdc 28, cdc 37 and cdc 4 arrested cells, as well as in wild type cells arrested in G1 phase in comparison to exponentially growing cells. There was however a significant increase in Ca2+ uptake in cdc 7 and cdc 24 arrested cells. The former is known to arrest before bud emergence and initiation of DNA synthesis; arrest of the latter affects bud formation while DNA synthesis continues. The results suggest that Ca2+ may have a role in bud formation and growth.
authors.affiliation: School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Anand
authors.forename: R
authors.initials: R
authors.lastname: Prasad
mesh_terms: D001692:Biological Transport; D002118:Calcium / Q000493:pharmacokinetics* / Q000502:physiology; D002453:Cell Cycle; D004271:DNA, Fungal / Q000096:biosynthesis; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D013696:Temperature
chemical_list: D004271:DNA, Fungal; D002118:Calcium