A follow-up investigation of offspring of parents with bipolar disorder.
Seven male children who each had a manic-depressive parent (five alos had a parent with unipolar depression) and 12 control children were studied. The proband children had shown a range of adjustment problems as infants and toddlers. Four years later, they continued to have substantial behavior problems, including ones that could be classified as DSM-III psychiatric diagnoses. On the basis of psychiatric interviews and psychological assessments, the proband children received more DSM-III diagnoses than the control children. Proband children reported internalizing symptoms; this pattern was corroborated by their mothers, who also characterized these children as showing antisocial behavior patterns.
Zahn-Waxler
C
C
Laboratory of Developmental Psychology, NIMH, Bethesda, MD 20892.
Mayfield
A
A
Radke-Yarrow
M
M
McKnew
D H
DH
Cytryn
L
L
Davenport
Y B
YB
D000275:Adjustment Disorders / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000175:diagnosis; D001714:Bipolar Disorder / Q000235:genetics*; D002648:Child; D002653:Child Behavior Disorders / Q000175:diagnosis*; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged