Secretory immunoglobulin A (sIgA) in the serum of cystic fibrosis patients.
Clearly increased sIgA values were found in cystic fibrosis patients in more than 70%. The highest concentrations were seen in patients with obstructive liver disease. There were no correlations between sIgA and liver-associated enzymes. Postmortem histology and sIgA correlated well. These data suggest a pertinent role of sIgA assessment in evaluation of hepatic involvement in cystic fibrosis.
Hein
J
J
Klinik für Kinderheilkunde, Bereiches Medizin, Wilhelm-Pieck-Universität Rostock, Deutsche Demokratische Republik.
Schober
S
S
Seyfarth
M
M
Brock
J
J
Kirschnick
H D
HD
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000276:immunology; D001987:Bronchiectasis / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000378:metabolism*; D007223:Infant; D008105:Liver Cirrhosis, Biliary / Q000276:immunology; D008297:Male
D007071:Immunoglobulin A, Secretory