title: Endoscopy of the gallbladder as control of gallstone therapy with methyl-tert-butyl ether.
abstract: We report on a 36-yr-old woman with six gallstones measuring 2.1 cm each. Within 21 h of methyl-tert-butyl ether (MTBE) treatment, the stones had dissolved to a small amount of residue. As could be seen from cholesterol concentrations of samples of aspirated gallbladder bile and MTBE fractions, the dissolution process was slow to begin with, and gained momentum during hours 6-11, after which it decelerated. We discontinued treatment after 20 h, since the stone residue showed no change. Cholecystoscopy performed with an Edwards angioscope via a catheter showed that there were no stone remnants, but that there were flat polyps on the gallbladder wall. One hour later, we stopped the therapy. Cholecystoscopy is a useful method of assessing the results of MTBE treatment.
authors.affiliation: Zentrum der Inneren Medizin, Johann Wolfgang Goethe-Universität, Frankfurt, FRG.
authors.forename: U
authors.initials: U
authors.lastname: Leuschner
authors.forename: A
authors.initials: A
authors.lastname: Hellstern
authors.forename: T
authors.initials: T
authors.lastname: Wendt
authors.forename: G
authors.initials: G
authors.lastname: Birkenfeld
authors.forename: M
authors.initials: M
authors.lastname: Leuschner
authors.forename: M
authors.initials: M
authors.lastname: Gatzen
authors.forename: W
authors.initials: W
authors.lastname: Kurtz
authors.forename: H
authors.initials: H
authors.lastname: Fischer
mesh_terms: D000328:Adult; D002769:Cholelithiasis / Q000175:diagnosis / Q000188:drug therapy*; D004724:Endoscopy; D004987:Ethers / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008738:Methyl Ethers
chemical_list: D004987:Ethers; D008738:Methyl Ethers; C043243:methyl tert-butyl ether