Somatosensory evoked potentials in chronic alcoholics with spasticity.
Somatosensory evoked potentials to median and bilateral tibial nerve stimulation were investigated in eight chronic alcoholics with spasticity, 12 patients with alcoholic polyneuropathy, and 11 normal subjects. Central conduction velocities from the third lumbar vertebra to the fifth cervical vertebra and from the 12th thoracic vertebra to the fifth cervical vertebra were significantly lower in the chronic alcoholics with spasticity than in the alcoholic polyneuropathy group and in the healthy nonalcoholic group. The result indicates that chronic alcoholics with spasticity have conduction disturbance in the posterior column and/or the medial lemniscus, which is considered to be due to alcoholic myelopathy and/or a brainstem lesion.
Kokubun
Y
Y
Department of Neurology, Nihon University School of Medicine, Tokyo.
Oishi
M
M
Takasu
T
T
Sakamaki
S
S
D000437:Alcoholism / Q000503:physiopathology*; D005073:Evoked Potentials, Somatosensory; D006801:Humans; D008875:Middle Aged; D009128:Muscle Spasticity / Q000503:physiopathology*; D009431:Neural Conduction; D009434:Neural Pathways