Quinidine-induced allergic granulomatous angiitis: an unusual cause of acute renal failure.
A case of systemic allergic-type vasculitis after the administration of quinidine and digoxin is described. The renal biopsy findings are unique in that they describe an arteritis with eosinophilic infiltration and non-caseating granulomata. We believe quinidine is the antigen that was responsible for the reported findings.
Quin
J
J
Westmead Hospital, NSW.
Adamski
M
M
Howlin
K
K
Jones
W
W
O'Neill
P
P
Stewart
G
G
Young
A
A
D058186:Acute Kidney Injury / Q000139:chemically induced*; D004077:Digoxin / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004802:Eosinophilia / Q000139:chemically induced*; D006099:Granuloma / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011802:Quinidine / Q000009:adverse effects*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced*
D004077:Digoxin; D011802:Quinidine