title: Treatment of multi-resistant urinary tract infections in patients with multiple sclerosis.
abstract: Multi-resistant nosocomial urinary tract infections occurring in thirty patients with neurogenic bladder dysfunction were treated with ciprofloxacin 100 mg twice daily Early bacteriological eradication was obtained in 48.3%, persistence in 34.5% and superinfection in 17.2%. Recurrence, 30 days after initial eradication occurred in 50% while late eradication was maintained in 35% and reinfection with another germ was noted in 15%. Most recurring and reinfecting germs were still susceptible to ciprofloxacin. The drug was well tolerated. The overall outcome was mainly determined by the vesico-urethral dysfunction itself and by the presence of indwelling bladder catheters.
authors.affiliation: Urology Department, Universiteit Leuven, Belgium.
authors.forename: H
authors.initials: H
authors.lastname: van Poppel
authors.forename: L
authors.initials: L
authors.lastname: Baert
mesh_terms: D001424:Bacterial Infections / Q000150:complications / Q000188:drug therapy*; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004352:Drug Resistance, Microbial; D006801:Humans; D009103:Multiple Sclerosis / Q000150:complications*; D001750:Urinary Bladder, Neurogenic / Q000150:complications; D014546:Urinary Catheterization; D014552:Urinary Tract Infections / Q000150:complications / Q000188:drug therapy*
chemical_list: D002939:Ciprofloxacin