title: The effects of meal-feeding and the diurnal cycle on lipogenesis in brown adipose tissue of rats.
abstract: A significant diurnal variation in the rates of lipogenesis in vivo in brown adipose tissue occurred in both virgin and lactating rats. On a meal-feeding regime of either a chow, high-sucrose, or high-lipid diet, there was a very large increase in BAT lipogenesis following the meal. The rates observed after the sucrose meal are the highest so far reported. There was no significant difference in BAT lipogenesis between lactating and virgin rats, contrary to previous reports by others. The pattern of stimulation of BAT lipogenesis by these feeding regimes was different from that for white adipose tissue and liver and was not correlated with plasma insulin levels.
authors.affiliation: Department of Biochemistry, University of Otago, Dunedin, New Zealand.
authors.forename: M P
authors.initials: MP
authors.lastname: Thompson
authors.forename: M R
authors.initials: MR
authors.lastname: Grigor
mesh_terms: D002001:Adipose Tissue, Brown / Q000187:drug effects / Q000378:metabolism*; D000821:Animal Feed; D000818:Animals; D002940:Circadian Rhythm; D004032:Diet; D004040:Dietary Carbohydrates / Q000494:pharmacology; D004041:Dietary Fats / Q000494:pharmacology; D005260:Female; D007328:Insulin / Q000097:blood; D007774:Lactation; D008055:Lipids / Q000096:biosynthesis*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004040:Dietary Carbohydrates; D004041:Dietary Fats; D007328:Insulin; D008055:Lipids