title: HLA typing in birdshot chorioretinopathy.
abstract: We examined 49 patients with birdshot chorioretinopathy in whom HLA typing had been performed. Of these 49 patients, 47 (95.9%) had the HLA-A29 antigen. The HLA-B12 (B44) antigen was also significantly associated with the disease, but this antigen is known to be in linkage disequilibrium with the antigen HLA-A29. The HLA-A2 antigen was less frequent in patients with birdshot chorioretinopathy than in the control group of normal European individuals (20% as compared to 44.6%).
authors.affiliation: Department of Ophthalmology, University of Gent, Belgium.
authors.forename: H A
authors.initials: HA
authors.lastname: Priem
authors.forename: A
authors.initials: A
authors.lastname: Kijlstra
authors.forename: L
authors.initials: L
authors.lastname: Noens
authors.forename: G S
authors.initials: GS
authors.lastname: Baarsma
authors.forename: J J
authors.initials: JJ
authors.lastname: De Laey
authors.forename: J A
authors.initials: JA
authors.lastname: Oosterhuis
mesh_terms: D002829:Choroid / Q000276:immunology; D006680:HLA Antigens / Q000032:analysis* / Q000235:genetics; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D059948:HLA-B44 Antigen; D006650:Histocompatibility Testing; D006801:Humans; D012164:Retinal Diseases / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology; D012307:Risk Factors; D014603:Uveal Diseases / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; C035524:HLA-A29 antigen; D015235:HLA-B Antigens; C035015:HLA-B12 antigen; D059948:HLA-B44 Antigen