Lichen sclerosus et atrophicus and autoimmunity--a study of 350 women.
A study of autoimmune related phenomena in 350 women with histologically confirmed lichen sclerosus et atrophicus revealed that 21.5% had one or more autoimmune related diseases, 21% had one or more first degree relatives with an autoimmune-related disease, 42% had an autoantibody at a titre greater than 1:20, and 59.5% had one or more of these autoimmune-related phenomena. No statistically significant differences in the natural history of lichen sclerosus et atrophicus were demonstrated between those patients with autoimmune-related phenomena and those without.
Meyrick Thomas
R H
RH
Department of Dermatology, St Bartholomew's Hospital, West Smithfield, London, UK.
Ridley
C M
CM
McGibbon
D H
DH
Black
M M
MM
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008875:Middle Aged; D012871:Skin Diseases / Q000276:immunology*
D001323:Autoantibodies