Variable RNA polymerase populations in the life cycle of Trypanosoma brucei.
DNA-dependent RNA polymerase from blood forms and culture forms of the parasitic protozoan Trypanosoma brucei was resolved into multiple peaks of activity by DEAE-Sephadex chromatography. The enzyme from the two forms was found to be different by several criteria, suggesting that it is subject to developmental control.
Tittawella
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Department of Microbiology, University of Umeå, Sweden.
D000818:Animals; D012321:DNA-Directed RNA Polymerases / Q000302:isolation & purification / Q000378:metabolism*; D007527:Isoenzymes / Q000302:isolation & purification / Q000378:metabolism*; D007700:Kinetics; D051381:Rats; D011919:Rats, Inbred Strains; D013816:Thermodynamics; D014346:Trypanosoma brucei brucei / Q000201:enzymology / Q000254:growth & development*
D007527:Isoenzymes; D012321:DNA-Directed RNA Polymerases