title: Disordered water metabolism: hyponatremia.
abstract: Normal osmoregulation is maintained by the proper function and interplay of factors influencing thirst, renal water metabolism, and vasopressin secretion. In pathophysiologic states, body water homeostasis is disrupted and hyponatremia ensures. Hyponatremia associated with cardiac failure, hepatic failure, respiratory failure, diabetes mellitus, the postoperative state, and other disorders is commonly found in the critical care setting. The pathophysiology, diagnosis, and treatment of hyponatremia are discussed.
authors.affiliation: Wayne State University School of Medicine, Detroit, Michigan.
authors.forename: N F
authors.initials: NF
authors.lastname: Rossi
authors.forename: P
authors.initials: P
authors.lastname: Cadnapaphornchai
mesh_terms: D001834:Body Water / Q000378:metabolism*; D006801:Humans; D007010:Hyponatremia / Q000378:metabolism* / Q000503:physiopathology / Q000628:therapy; D007674:Kidney Diseases / Q000378:metabolism / Q000503:physiopathology; D009102:Multiple Organ Failure / Q000378:metabolism / Q000503:physiopathology; D009994:Osmolar Concentration; D013894:Thirst / Q000502:physiology; D014667:Vasopressins / Q000378:metabolism
chemical_list: D014667:Vasopressins