Failure of a single dose of 100 mg ofloxacin in lower urinary tract infections in females.
A single dose of 100 mg ofloxacin was compared with a multiple dose of cotrimoxazole in lower urinary tract infections in 137 women. The elimination rate was significantly lower in the single dose treated group of patients in spite of all strains being in vitro susceptible in this group.
Ode
B
B
Department of Infectious Diseases, University of Lund, Malmö General Hospital, Sweden.
Walder
M
M
Forsgren
A
A
D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004338:Drug Combinations / Q000008:administration & dosage / Q000627:therapeutic use; D004927:Escherichia coli Infections / Q000188:drug therapy*; D005260:Female; D006801:Humans; D015242:Ofloxacin; D010078:Oxazines / Q000008:administration & dosage* / Q000627:therapeutic use; D011897:Random Allocation; D013420:Sulfamethoxazole / Q000008:administration & dosage / Q000627:therapeutic use; D014295:Trimethoprim / Q000008:administration & dosage / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014552:Urinary Tract Infections / Q000188:drug therapy*
D000892:Anti-Infective Agents, Urinary; D004338:Drug Combinations; D010078:Oxazines; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D015242:Ofloxacin; D014295:Trimethoprim; D013420:Sulfamethoxazole