Adenosine-5'-triphosphate levels in experimental CaNT and Fib/t tumours of varying volume and degree of hypoxia.
The variation of adenosine-5'-triphosphate (ATP) content per unit mass of tumour, versus tumour volume was measured in vivo under normoxic conditions, using CaNT and Fib/t murine tumours grown in CBA and WHT mice respectively. A monotonically decreasing relation was found. Artificially induced tumour hypoxia resulting from 15 min of clamping was accompanied by reduced ATP levels.
Szeinfeld
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Research Institute for Medical Biophysics SA Medical Research Council, Tygerberg, South Africa.
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D004260:DNA Repair; D000860:Hypoxia; D051379:Mice; D009374:Neoplasms, Experimental / Q000378:metabolism* / Q000473:pathology
D000255:Adenosine Triphosphate