title: Acyclovir in human breast milk.
abstract: Acyclovir concentration was measured by radioimmunoassay in the serum and milk of a lactating woman who was treated with oral acyclovir for herpes zoster. Daily serum and milk samples showing milk concentrations that averaged being 3.24-fold higher than serum levels suggest a low infant dose. The elimination phase demonstrated a half-life of 2.8 hours in milk.
authors.affiliation: Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City.
authors.forename: L J
authors.initials: LJ
authors.lastname: Meyer
authors.forename: P
authors.initials: P
authors.lastname: de Miranda
authors.forename: N
authors.initials: N
authors.lastname: Sheth
authors.forename: S
authors.initials: S
authors.lastname: Spruance
mesh_terms: D000212:Acyclovir / Q000032:analysis / Q000097:blood / Q000493:pharmacokinetics*; D000328:Adult; D005260:Female; D006207:Half-Life; D006801:Humans; D008895:Milk, Human / Q000032:analysis*; D011863:Radioimmunoassay
chemical_list: D000212:Acyclovir