Acetylcysteine for urinary tract mucolysis.
The use of acetylcysteine is described for the relief of mucinous obstruction of the distal ureter after a mid ureteral replacement with ileum. Acetylcysteine (300 cc of 1 per cent) was instilled at low pressure via a nephrostomy tube following documentation of the obstruction with a nephrostogram. Patency of the ureter was achieved within 5 minutes. Re-obstruction ensued but it resolved with repeat percutaneous instillation of acetylcysteine. Patency, confirmed by a followup nuclear renogram at 4 months, has been maintained with 700 mg. acetylcysteine orally 4 times a day.
Benderev
T V
TV
Department of Urology, Northwestern University, Chicago, Illinois.
D000111:Acetylcysteine / Q000627:therapeutic use*; D000328:Adult; D006801:Humans; D007082:Ileum / Q000378:metabolism / Q000637:transplantation; D008297:Male; D009093:Mucus / Q000378:metabolism*; D011183:Postoperative Complications / Q000188:drug therapy; D012008:Recurrence; D014513:Ureter / Q000601:surgery*; D014517:Ureteral Obstruction / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery
D000111:Acetylcysteine