Prevalence of giardiasis in patients with cystic fibrosis.
A group of 107 patients with cystic fibrosis and a control group of 64 normal members of households of patients with cystic fibrosis were surveyed for Giardia lamblia cysts and trophozoites by counterimmunoelectrophoresis of fecal samples. The patient group had a significantly higher rate of infestation than the control group (28.0% vs 6.3%, P = 0.0006), and the disparity between the two groups increased with age (P = 0.005). Aside from cystic fibrosis, all risk factors examined were without influence, except for the presence of household members less than or equal to 5 years of age. We conclude that our patients with cystic fibrosis have a previously unrecognized increased prevalence of giardiasis compared with that in a control population.
Roberts
D M
DM
Department of Pediatrics, School of Medicine, Tulane University, New Orleans, LA 70112.
Craft
J C
JC
Mather
F J
FJ
Davis
S H
SH
Wright
J A
JA
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications*; D005243:Feces / Q000032:analysis; D005260:Female; D005541:Forced Expiratory Volume; D005872:Giardia / Q000032:analysis; D005873:Giardiasis / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008145:Louisiana; D008297:Male