Patient-controlled analgesia using butorphanol for postoperative pain relief: an open-label study.
Patient-controlled analgesia (PCA) has been studied extensively for the treatment of postoperative pain using narcotic analgesics. Butorphanol, a nonnarcotic injectable analgesic, has not previously been investigated using this drug delivery mechanism. Twenty-five patients undergoing general abdominal surgery and general anesthesia used a PCA device with butorphanol as the analgesic agent. Most patients (84%) were able to obtain excellent postoperative pain relief. The role of butorphanol in the management of postoperative pain should be expanded to include patient-controlled drug delivery.
Wermeling
D P
DP
Drug Product Evaluation Unit, College of Pharmacy, University of Kentucky Medical Center, Lexington.
Foster
T S
TS
Farrington
E A
EA
Witt
W O
WO
Gallion
H H
HH
Donaldson
E
E
van Nagell
J R
JR
Outman
W R
WR
McPherson
D P
DP
D000328:Adult; D000368:Aged; D002077:Butorphanol / Q000008:administration & dosage*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009019:Morphinans / Q000008:administration & dosage*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D012646:Self Administration
D009019:Morphinans; D002077:Butorphanol