title: [Neurocryptococcosis in childhood. Report of 3 cases in the 1st decade of life].
abstract: The authors report three cases of central nervous system cryptococcosis in children in the first decade of life, from Rio Grande do Sul State, Brazil. Diagnosis was supported by demonstration of Cryptococcus neoformans with India-ink preparations of the spinal fluid and Sabouraud's media culture. Clinical presentation included acute, subacute and chronic forms. Increased intracranial pressure and hydrocephalus were the complications during the course of the disease, and a ventriculoperitoneal shunt was used in one case. Undernutrition was associated with all cases and tubercle bacillus infection with one. Specific therapy was administered to the three patients. One patient was cured and the other two died.
authors.affiliation: Hospital da Criança Santo Antonio (HCSA), Porto Alegre.
authors.forename: M H
authors.initials: MH
authors.lastname: Fontana
authors.forename: M F
authors.initials: MF
authors.lastname: Coutinho
authors.forename: E dos S
authors.initials: Edos S
authors.lastname: Camargo
authors.forename: B
authors.initials: B
authors.lastname: Soviero
authors.forename: S S
authors.initials: SS
authors.lastname: Lima
authors.forename: R
authors.initials: R
authors.lastname: Matusiak
authors.forename: C G
authors.initials: CG
authors.lastname: Dias
mesh_terms: D000367:Age Factors; D000666:Amphotericin B / Q000627:therapeutic use; D001927:Brain Diseases / Q000453:epidemiology / Q000382:microbiology*; D001938:Brazil; D002555:Cerebrospinal Fluid / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D003453:Cryptococcosis / Q000188:drug therapy / Q000453:epidemiology / Q000401:mortality; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000382:microbiology
chemical_list: D000666:Amphotericin B
vernacular_title: Neurocriptococose na infância. Relato de três casos na primeira décade de vida.