title: The confirmation of norethindrone aromatization in primary human hepatocytes by the Vitafiber-II cell culture system.
abstract: A portion of norethindrone (17 alpha-ethynyl-19-nortestosterone) was confirmed to be aromatized to ethynyl estradiol (17 alpha-ethynyl estradiol) in primary human hepatocytes cultured using the Vitafiber-II cell culture system.
authors.affiliation: Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: J
authors.initials: J
authors.lastname: Kitawaki
authors.forename: K
authors.initials: K
authors.lastname: Shiroshita
authors.forename: M
authors.initials: M
authors.lastname: Urabe
authors.forename: J
authors.initials: J
authors.lastname: Sasaki
authors.forename: M
authors.initials: M
authors.lastname: Fukuoka
authors.forename: K
authors.initials: K
authors.lastname: Naitoh
authors.forename: H
authors.initials: H
authors.lastname: Honjo
authors.forename: H
authors.initials: H
authors.lastname: Okada
mesh_terms: D000818:Animals; D001141:Aromatase / Q000378:metabolism; D002478:Cells, Cultured; D003470:Culture Media; D004997:Ethinyl Estradiol / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D009640:Norethindrone / Q000378:metabolism*; D011817:Rabbits
chemical_list: D003470:Culture Media; D004997:Ethinyl Estradiol; D001141:Aromatase; D009640:Norethindrone