title: Vaccines to protect Hereford cattle against the cattle tick, Boophilus microplus.
abstract: Vaccines made from gut and gut and synganglion tissue dissected from Boophilus microplus gave 87% and 80% protection, respectively, compared with adjuvant-injected controls in cattle against three infestations with 20,000 larval ticks administered over 14 days. A vaccine prepared from synganglion alone did not protect cattle. Ticks collected from vaccinated cattle produced 95% and 91% fewer eggs, respectively, than ticks from control animals. Vaccinated cattle were protected (36%) 7 months after they had been immunized with tick antigens. Antibody responses to the vaccines were detected by enzyme-linked immunosorbent assay (ELISA).
authors.affiliation: Department of Parasitology, University of Queensland, St Lucia, Australia.
authors.forename: J P
authors.initials: JP
authors.lastname: Opdebeeck
authors.forename: J Y
authors.initials: JY
authors.lastname: Wong
authors.forename: L A
authors.initials: LA
authors.lastname: Jackson
authors.forename: C
authors.initials: C
authors.lastname: Dobson
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology / Q000517:prevention & control*; D010270:Parasite Egg Count; D013984:Tick Infestations / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*; D013987:Ticks / Q000276:immunology*; D014611:Vaccination; D014612:Vaccines
chemical_list: D000906:Antibodies; D014612:Vaccines