Charcot on Parkinson's disease.
Charcot saluted Parkinson for his early observations, but condemned his use of the term "paralysis agitans." He emphasized that patients were neither dramatically weak nor were they necessarily plagued with tremor. Charcot suggested the name "Parkinson's disease," although he could not resist the comment in his amphitheater lecture series at the Salpêtrière that French physicians (unnamed) had probably described the disorder before 1817. Tremor, rigidity, postural instability, and bradykinesia were all recognized by Charcot. He classified the disorder as a "névrose," meaning a neurologic disorder without a known pathologic lesion, and found little benefit from therapies available at the time, including belladonna and ergot products.
Goetz
C G
CG
Department of Neurological Sciences, Rush-Presbyterian-St. Lukes Medical Center, Chicago, Illinois 60612.
D005602:France; D049672:History, 19th Century; D006801:Humans; D010300:Parkinson Disease / Q000266:history*