title: A dose homogeneity index for evaluating 192Ir interstitial breast implants.
abstract: To evaluate and optimize dose homogeneity of 192Ir interstitial breast implants, we define a quantity, the dose homogeneity index (DHI), as follows: DHI = [V(TDR)--V(HDR)]/V(TDR), where V(TDR) denotes the total treatment volume enclosed by the prescribed treatment dose rate (TDR) and V(HDR) denotes the volume enclosed by high-dose rate (HDR), which is 1.5 X TDR or greater. We have used the DHI to examine and compare 192Ir double-plane implants of various sizes planned by the Memorial system or the Tufts system. Criteria have been suggested for the number of planes required for implants in a given treatment volume. Anderson's volume-dose histogram with inverse square suppression is adopted for illustration.
authors.affiliation: Department of Radiation Oncology, Tufts-New England Medical Center, Boston, Massachusetts 02111.
authors.forename: A
authors.initials: A
authors.lastname: Wu
authors.forename: K
authors.initials: K
authors.lastname: Ulin
authors.forename: E S
authors.initials: ES
authors.lastname: Sternick
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation*; D001943:Breast Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007496:Iridium Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D011879:Radiotherapy Dosage
chemical_list: D007496:Iridium Radioisotopes