Hydrophilic microporous polyurethane versus expanded PTFE grafts as substitutes in the carotid arteries of dogs. A limited study.
A novel, microporous, hydrophilic polyether urethane-urea (PEUU) vascular graft was compared with expanded PTFE in the canine carotid artery. At implantation times ranging from 4 h to 6 months, all the PEUU grafts were found to be occluded while of the PTFE grafts, only those implanted for 1 week and 6 months were blocked. Histopathological analysis of the explanted grafts and their capsules revealed an ongoing inflammatory reaction at the anastomotic sites of the PEUU grafts.
Martz
H
H
Laboratory of Experimental Surgery, Laval University, Quebec City, Canada.
Paynter
R
R
Ben Slimane
S
S
Beaudoin
G
G
Guidoin
R
R
Borzone
J
J
Ben Simhon
H
H
Satin
R
R
Sheiner
N
N
D000818:Animals; D001672:Biocompatible Materials; D001807:Blood Vessel Prosthesis; D002339:Carotid Arteries / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D011138:Polytetrafluoroethylene; D011140:Polyurethanes
D001672:Biocompatible Materials; D011140:Polyurethanes; D011138:Polytetrafluoroethylene; C044690:polyetherurethane urea