title: Aspects of C1-inhibitor biochemistry and pathophysiology.
abstract: During the last few years, the structure and function of human C1-inhibitor have been elucidated. Chromogenic substrate assays for determination of C1-inhibitor activity in plasma are available, and have proved to be of value not only for the diagnosis of hereditary angioedema but also in acquired diseases involving C1-inhibitor, such as cold urticaria and autoimmune disorders as well as acute-phase types of disease states.
authors.affiliation: Department of Clinical Chemistry, Umeå University Hospital, Sweden.
authors.forename: T K
authors.initials: TK
authors.lastname: Nilsson
mesh_terms: D003174:Complement C1 Inactivator Proteins / Q000502:physiology*; D006801:Humans
chemical_list: D003174:Complement C1 Inactivator Proteins