Mathematical models of cumulative effect and optimization of fractionation regimes.
Different (most known) mathematical models are shortly described and basic assumptions the individual models are based on are discussed and critically examined. Advantages and shortages of individual models are mentioned. A semiphenomenological model is then used to demonstrate some possibilities how to make use of the mathematical models in attempts of optimizing the fractionation approaches in individual cases.
Judas
L
L
Oncological clinic of Faculty Hospital, Prague.
Lokajícek
M
M
Prokes
K
K
D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D011878:Radiotherapy; D011879:Radiotherapy Dosage