title: [Percutaneous transhepatic lysis of gallstones using methyl tert-butyl ether. Report on 15 patients].
abstract: In 15 patients (13 women and two men) with cholesterol stones in the gall-bladder a special (Thistle) catheter was introduced into the gall-bladder under local anaesthesia by percutaneous transhepatic puncture. Methyl-tert-butyl ether, 2-15 ml, was injected via the catheter and removed again after 2 min. The number of stones per gall-bladder averaged 6.3 (1-20), size of stones 1.7 cm (0.5-2.8 cm), and duration of treatment 11.9 h (5-24 h). The stones dissolved in 13 patients (87%). In three patients stone débris remained: in one it was ultimately sucked out after reduction of the amount of débris with an EDTA-containing solution. The side effects of treatment--nausea and vomiting--were minor. In one patient there was a leak of bile from the gall-bladder after the procedure; a cholecystectomy was uneventfully performed. Another patient developed haemobilia which responded to conservative treatment. MTBE treatment has thus proved to be a successful and cheap method, low in side effects, in the treatment of patients with gall-stones.
authors.affiliation: Zentrum der Inneren Medizin, Klinikum der Universität Frankfurt/Main.
authors.forename: A
authors.initials: A
authors.lastname: Hellstern
authors.forename: M
authors.initials: M
authors.lastname: Leuschner
authors.forename: H
authors.initials: H
authors.lastname: Fischer
authors.forename: D
authors.initials: D
authors.lastname: Lazarovici
authors.forename: S
authors.initials: S
authors.lastname: Güldütuna
authors.forename: W
authors.initials: W
authors.lastname: Kurtz
authors.forename: U
authors.initials: U
authors.lastname: Leuschner
mesh_terms: D000328:Adult; D000368:Aged; D002404:Catheterization; D002769:Cholelithiasis / Q000188:drug therapy*; D004987:Ethers / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008738:Methyl Ethers; D008875:Middle Aged; D012997:Solvents / Q000008:administration & dosage*
chemical_list: D004987:Ethers; D008738:Methyl Ethers; D012997:Solvents; C043243:methyl tert-butyl ether
vernacular_title: Perkutan-transhepatische Lyse von Gallenblasensteinen mit Methyl-tert-butyl-äther. Bericht über 15 Patienten.