title: A prospective, randomized study comparing highly selective vagotomy and extended highly selective vagotomy in patients with duodenal ulcer.
abstract: The recurrence rate of duodenal ulcer after highly selective vagotomy is nearly 10 percent. To diminish this percentage, extended highly selective vagotomy with sectioning the gastroepiploic nerves has been proposed in order to reduce postoperative gastric acid secretion. We have prospectively compared the decrease in gastric acid secretion through measurement of basal acid output, maximal acid output, and peak acid output in patients who underwent highly selective vagotomy or extended highly selective vagotomy. No significant differences in postoperative gastric acid secretion were found and, therefore, no changes in the probability of postoperative recurrence of duodenal ulcer were seen.
authors.affiliation: Department of Surgery, San José Hospital, Santiago.
authors.forename: I
authors.initials: I
authors.lastname: Braghetto
authors.forename: A
authors.initials: A
authors.lastname: Csendes
authors.forename: M
authors.initials: M
authors.lastname: Lazo
authors.forename: P
authors.initials: P
authors.lastname: Rebolledo
authors.forename: A
authors.initials: A
authors.lastname: Díaz
authors.forename: A
authors.initials: A
authors.lastname: Bardavid
authors.forename: A
authors.initials: A
authors.lastname: Bahamonde
authors.forename: G
authors.initials: G
authors.lastname: Thomet
mesh_terms: D000293:Adolescent; D000328:Adult; D004381:Duodenal Ulcer / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005744:Gastric Acid / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011300:Preoperative Care; D011446:Prospective Studies; D011897:Random Allocation; D014629:Vagotomy, Proximal Gastric