title: Metaphase association of mammalian chromosomes.
abstract: The association behavior of chromosomes bearing nucleolar organizer region (NOR) and (or) C-heterochromatin in metaphase plates was analyzed. Different species with an informative chromosomal localization of NOR and C-heterochromatin were evaluated. Several examples indicate that the well-known metaphase association is not due to NORs or NOR activity per se. Other mechanisms such as ectopic pairing are responsible for the association. These types of pairing seem to be enhanced by the chromatin-decondensing effect of nearby NOR activity.
authors.affiliation: Abteilung Klinische Genetik, Universität Ulm, Federal Republic of Germany.
authors.forename: U
authors.initials: U
authors.lastname: Mayr-Wohlfart
authors.forename: S
authors.initials: S
authors.lastname: Adolph
authors.forename: C
authors.initials: C
authors.lastname: Klett
authors.forename: H
authors.initials: H
authors.lastname: Hameister
mesh_terms: D000818:Animals; D003411:Arvicolinae; D002415:Cats; D002417:Cattle; D002460:Cell Line; D002478:Cells, Cultured; D002871:Chromosome Banding; D002875:Chromosomes / Q000648:ultrastructure*; D006801:Humans; D007399:Interphase; D007621:Karyotyping; D008253:Macaca mulatta; D008677:Metaphase; D051379:Mice; D011896:Rana temporaria; D013045:Species Specificity