Lymphokine-activated killer cell lysis of human neuroblastoma cells: a model for purging tumor cells from bone marrow.
Evidence is presented that neuroblastoma tumor cells in host bone marrow is susceptible to autologous lymphokine-activated killer cells (LAK). Thus, immunologic purging of bone marrow with LAK may be considered as a tool in the arsenal of bone marrow purging-for autologous bone marrow transplantation.
Ades
E W
EW
Department of Pathology, Medical College of Georgia, Augusta 30912-0300.
Peacocke
N
N
Sabio
H
H
D001853:Bone Marrow / Q000473:pathology*; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D009447:Neuroblastoma / Q000473:pathology*; D014407:Tumor Cells, Cultured