title: Biosynthesis and biotransformation of ether lipids.
abstract: Some naturally occurring as well as synthetic ether lipids are biologically active. In certain cases, the effects of these substances are enhanced, in others, they are inhibited by compounds that were isolated from natural sources or prepared by chemical synthesis. The biotransformation of natural or "unnatural" ether lipids in microorganisms, plant or animal tissue also can lead to substances that elicit biological effects. The production of such compounds through various biotechnological techniques is a field wide open for future exploration. In addition to animal cell cultures, plant cell cultures may become useful tools in biomedical studies concerned with ether lipids.
authors.affiliation: Federal Center for Lipid Research, H.P. Kaufmann-Institute, Münster, Federal Republic of Germany.
authors.forename: H K
authors.initials: HK
authors.lastname: Mangold
authors.forename: N
authors.initials: N
authors.lastname: Weber
mesh_terms: D000818:Animals; D005995:Glyceryl Ethers / Q000096:biosynthesis* / Q000138:chemical synthesis / Q000378:metabolism / Q000627:therapeutic use; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000096:biosynthesis* / Q000138:chemical synthesis; D010742:Phospholipid Ethers / Q000096:biosynthesis* / Q000138:chemical synthesis / Q000378:metabolism / Q000627:therapeutic use; D010944:Plants / Q000378:metabolism
chemical_list: D005995:Glyceryl Ethers; D008055:Lipids; D010742:Phospholipid Ethers