[C-reactive protein, lactate and LDH isoenzymes in the cerebrospinal fluid in the diagnosis in childhood meningitis].
C reactive protein lactate and LDH isoenzymes were quantified in CSF of 32 children with meningitis (27 bacterial and 5 viral). Results in cases with bacterial meningitis were as follows. C reactive protein sensitivity was 11.1% and specificity was 100%. Lactate sensitivity was 33.3% and its specificity was 80%. LDH1 and LDH5 had a sensitivity of 44.4%, and specificities of 100 and 60% respectively. Considering these results an has believe that none of these tests is definitive in diagnosis of bacterial meningitis in children.
Castro-Gago
M
M
Departamento de Pediatría, Hospital General de Galicia, Facultad de Medicina, Universidad de Santiago de Compostela.
Couce
M L
ML
Losada
M C
MC
González
M C
MC
Novo
I
I
España
M R
MR
Rodríguez-Segade
S
S
D002097:C-Reactive Protein / Q000134:cerebrospinal fluid*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000134:cerebrospinal fluid*; D007773:Lactates / Q000134:cerebrospinal fluid*; D008581:Meningitis / Q000134:cerebrospinal fluid* / Q000175:diagnosis
D007527:Isoenzymes; D007773:Lactates; D002097:C-Reactive Protein; D007770:L-Lactate Dehydrogenase
La proteína C reactiva, el lactato y los isoenzimas de la LDH a nivel del LCR en el diagnóstico de las meningitis infantiles.