[Renal cell carcinoma with a spindle-cell element--sarcomatous or sarcomatoid?].
In this study the light microscopic and electron microscopic findings in two renal cell carcinomas with spindle-cell elements are described. The ultrastructural features of the spindle-cell element of sarcomatoid renal cell carcinoma have previously been documented, namely pentalaminar desmosomes, basal lamina formation and intracytoplasmic lumina with microvilli. The electron microscopic findings in the 2 cases described here showed mesenchymal rather than epithelial differentiation. It would appear that some renal cell carcinomas with a spindle-cell element are true carcinosarcomas, rather than sarcomatoid renal cell carcinoma.
Rudman
A M
AM
Department Anatomiese Patologie, Universiteit van die Oranje-Vrystaat, Bloemfontein.
de Bruin
B
B
Duyvené de Wit
L J
LJ
Cooper
G M
GM
D000328:Adult; D002277:Carcinoma / Q000648:ultrastructure*; D002292:Carcinoma, Renal Cell / Q000648:ultrastructure*; D002296:Carcinosarcoma / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000648:ultrastructure*; D008297:Male
Renaalselkarsinoom met 'n spoelvormige selelement--sarkomateus of sarkomatoïed?