title: Cryptococcosis of the colon resembling Crohn's disease in a patient with the hyperimmunoglobulinemia E-recurrent infection (Job's) syndrome.
abstract: A 29-yr-old woman presenting with granulomatous colitis and a chronic perirectal abscess was found to have localized cryptococcosis associated with the hyperimmunoglobulinemia E-recurrent infection (Job's) syndrome. Similarity to previous cases of esophageal cryptococcosis and ileocecal histoplasmosis suggests an association between the hyperimmunoglobulinemia E-recurrent infection syndrome and localized fungal infections of the alimentary tract. To our knowledge, this is the first well-documented case of cryptococcosis confined to the colon and perirectal tissues.
authors.affiliation: University of South Carolina School of Medicine, Columbia.
authors.forename: J O
authors.initials: JO
authors.lastname: Hutto
authors.forename: C S
authors.initials: CS
authors.lastname: Bryan
authors.forename: F L
authors.initials: FL
authors.lastname: Greene
authors.forename: C J
authors.initials: CJ
authors.lastname: White
authors.forename: J I
authors.initials: JI
authors.lastname: Gallin
mesh_terms: D000328:Adult; D003108:Colonic Diseases / Q000150:complications / Q000473:pathology*; D003424:Crohn Disease / Q000473:pathology*; D003453:Cryptococcosis / Q000150:complications / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007589:Job Syndrome / Q000150:complications / Q000473:pathology*; D010585:Phagocyte Bactericidal Dysfunction / Q000473:pathology*