title: Analysis of a protocol for an autologous blood transfusion program for total joint replacement surgery.
abstract: This retrospective study analysed an autologous blood transfusion program for total joint replacement surgery. A group of 99 patients receiving autologous blood transfusion was compared with a control group of 55 patients. One-unit phlebotomies were done 14 and 7 days before surgery. The whole blood was transfused intraoperatively. Preoperative hemoglobin values were within the normal range for all patient groups except the female autologous blood group for which the mean value was 122 +/- 11.3 g/L. Due to perioperative hemodilution, the postoperative hemoglobin values were substantially lower than preoperative values for all groups. Mean intraoperative blood loss was similar for the autologous and control groups (650 to 750 ml). No adverse reactions were associated with the autologous transfusions and 74% of the autologous group received autologous blood only. From this analysis a 3-week, three-unit preoperative collection was proposed for future use. A standardized protocol will allow logistical ease and implementation of the program for various surgical procedures.
authors.affiliation: Department of Surgery, Calgary General Hospital, Alta.
authors.forename: B J
authors.initials: BJ
authors.lastname: MacFarlane
authors.forename: L
authors.initials: L
authors.lastname: Marx
authors.forename: K
authors.initials: K
authors.lastname: Anquist
authors.forename: G
authors.initials: G
authors.lastname: Pineo
authors.forename: J
authors.initials: J
authors.lastname: Chenger
authors.forename: E
authors.initials: E
authors.lastname: Cassol
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001804:Blood Transfusion, Autologous / Q000009:adverse effects; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006621:Hip Joint / Q000601:surgery; D006622:Hip Prosthesis; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D006454:Hemoglobins