title: Direct and indirect evaluation of lesions obstructing the carotid bifurcation. A comparison of Doppler spectrum analysis with angiography.
abstract: The diagnostic accuracy of real-time continuous wave (c.w.) Doppler spectrum analysis and of indirect periorbital Doppler examination for detecting carotid bifurcation disease was evaluated. The results of non-invasive studies were compared with contrast arteriograms of patients studied for symptomatic cerebrovascular disease (91%) or for asymptomatic bruits (9%). Periorbital examination was insensitive to less than 75% carotid stenoses and sensitivity to severe stenoses or occlusions was respectively 56% and 85% (mean 73%). Mean sensitivity of real-time C.W. Doppler spectrum was 93% and sensitivity to stenoses of less than 45% diameter reduction was equal to 76%, while specificity in identifying normal carotid arteries was 89% for an accuracy of the method of 91%. Positive and negative predicting values were respectively 89% and 93%. Direct Doppler interrogation of the carotid arteries with real-time C.W. Doppler spectrum analysis was able to distinguish operable stenoses from inoperable occlusions in 87% of the cases.
authors.affiliation: Department of Surgery, University of Brescia, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Floriani
authors.forename: S
authors.initials: S
authors.lastname: Bonardelli
authors.forename: N
authors.initials: N
authors.lastname: Portolani
authors.forename: S M
authors.initials: SM
authors.lastname: Giulini
authors.forename: U
authors.initials: U
authors.lastname: Tambussi
authors.forename: G
authors.initials: G
authors.lastname: Tiberio
mesh_terms: D000792:Angiography; D002339:Carotid Arteries / Q000000981:diagnostic imaging* / Q000473:pathology; D002340:Carotid Artery Diseases / Q000175:diagnosis*; D006801:Humans; D014463:Ultrasonography