Juvenile nasopharyngeal angiofibroma: an update of the UCLA experience, 1960-1985.
The UCLA experience with juvenile angiofibroma (JNA) over a 25-year period is reviewed. There were 83 patients, the majority being adolescent males. Surgery was the primary method of treatment for disease not extending intracranially; 63 of 68 patients (92.5%) became asymptomatic with this modality. In patients treated with a single course of primary radiation, 10 of 14 (78.5%) became asymptomatic. Trends in diagnosis and treatment were evaluated. Contrast computerized tomography reliably assesses tumor extent. Preoperative arteriography is essential for the evaluation and embolization of feeding vessels; this in turn significantly reduces operative blood loss and the need for transfusions. Radiotherapy should be reserved for disease extending intracranially and should be in doses of 3,600 cGy or larger.
Economou
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Jonsson Comprehensive Cancer Center, UCLA School of Medicine 90024-1624.
Abemayor
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Ward
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PH
D000293:Adolescent; D000328:Adult; D000792:Angiography; D002648:Child; D005260:Female; D005350:Fibroma / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D008297:Male; D008499:Medical Records; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy / Q000601:surgery*