title: Correlation of the fibrinogen level with blood pressure and plasma renin activity in rats with early Goldblatt hypertension.
abstract: Goldblatt hypertension was induced in rats by constricting the renal artery on one side. In one group of animals the contralateral kidney remained untouched (two-kidney hypertension), while in the other it was removed (one-kidney hypertension). In the two-kidney hypertension group, renin activity was higher than in the control animals, the fibrinogen was normal both in arterial and venous blood while in one-kidney hypertension the PRA was normal, but the fibrinogen was increased. A close significant correlation could be demonstrated between blood pressure and fibrinogen.
authors.affiliation: First Department of Medicine, University Medical School, Szeged, Hungary.
authors.forename: S
authors.initials: S
authors.lastname: Sonkodi
authors.forename: I
authors.initials: I
authors.lastname: Sohár
authors.forename: E
authors.initials: E
authors.lastname: Stumpf
mesh_terms: D000818:Animals; D001158:Arteries; D001794:Blood Pressure; D005340:Fibrinogen / Q000378:metabolism*; D006978:Hypertension, Renovascular / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D051381:Rats; D012083:Renin / Q000097:blood*; D014680:Veins
chemical_list: D005340:Fibrinogen; D012083:Renin