Gastric mucosal dissection using the Nd-YAG laser synthetic sapphire crystal contact probe. Development of an endoscopic method for the treatment of pancreatic pseudocysts.
A canine gastric-ulcer model was developed to evaluate the safety and effectiveness of the neodymium yttrium-aluminum-garnet (Nd-YAG) laser synthetic sapphire crystal contact probe in intraluminal gastric dissection. The purpose of the study was to assess the potential endoscopic application of the Nd-YAG contact probe in cystogastrostomy for the treatment of selected patients with pancreatic pseudocyst. Seven dogs were used in the study. In the first two dogs, full-thickness linear incisions through the gastric wall demonstrated the Nd-YAG contact probe could be used for a full-thickness gastrostomy dissection. In the other five dogs, gastric ulcers were created by injection of morrhuate sodium (5%). Gastric mucosal dissection with the Nd-YAG contact probe was performed without difficulty. Hemostasis was obtained with either the Nd-YAG contact probe or noncontact fiber, and all areas of dissection and ulcer beds healed within 35 days. The Nd-YAG laser contact endoscopic delivery system appears to be a promising technique for intraluminal dissection.
ReMine
S G
SG
Department of Surgery, Lahey Clinic Medical Center, Burlington, MA 01805.
Setzer
S E
SE
Shapshay
S M
SM
D000818:Animals; D004285:Dogs; D019723:Endoscopes; D004724:Endoscopy / Q000379:methods; D005753:Gastric Mucosa / Q000601:surgery*; D005774:Gastrostomy; D006488:Hemostasis, Surgical / Q000379:methods; D053685:Laser Therapy / Q000295:instrumentation / Q000379:methods; D010181:Pancreatic Cyst / Q000601:surgery*; D010192:Pancreatic Pseudocyst / Q000601:surgery*; D013276:Stomach Ulcer / Q000601:surgery