title: [Pediatric neuroblastoma with early bilateral blindness].
abstract: The authors present the case history of a child with neuroblastoma and early infiltration of the orbit accompanied by bilateral blindness. The typical clinical signs developed later. The thickening of the periosteum infiltrated by the tumor in the lateral wall of the orbit was demonstrated by computerized tomography. This may be regarded as an early sign of infiltration of the orbit by the neuroblastoma. In the case reported here a severe inflammatory reaction developed in the left orbit and anterior segment during massive chemotherapy and melted the cornea.
authors.affiliation: Abteilung Augenheilkunde, Medizinische Fakultät, Rheinisch-Westfälischen Technischen, Hochschule Aachen.
authors.forename: M
authors.initials: M
authors.lastname: Reim
authors.forename: H C
authors.initials: HC
authors.lastname: Müther
authors.forename: J H
authors.initials: JH
authors.lastname: Karstens
authors.forename: H
authors.initials: H
authors.lastname: Sieverts
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000473:pathology*; D001766:Blindness / Q000473:pathology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D009447:Neuroblastoma / Q000473:pathology / Q000556:secondary*; D009915:Orbit / Q000473:pathology; D009918:Orbital Neoplasms / Q000473:pathology / Q000556:secondary*; D014057:Tomography, X-Ray Computed
vernacular_title: Kindliches Neuroblastom mit frühzeitiger beidseitiger Erblindung.