title: Amiodarone pulmonary toxicity presenting as a solitary lung mass.
abstract: Following treatment with amiodarone, a patient developed weight loss, fatigue and severe myopathy, without respiratory symptoms. A solitary lung infiltrate, impaired thyroid and liver function tests, and leukocytosis were evident. Biopsies from the lung lesion, liver, and bone marrow revealed foam cells. All these signs and symptoms subsided following cessation of amiodarone therapy. It is demonstrated that amiodarone may induce a localized lung lesion rather than diffuse pulmonary disease.
authors.affiliation: Department of Medicine B, Hadassah University Hospital, Jerusalem, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Arnon
authors.forename: I
authors.initials: I
authors.lastname: Raz
authors.forename: T
authors.initials: T
authors.lastname: Chajek-Shaul
authors.forename: N
authors.initials: N
authors.lastname: Berkman
authors.forename: S
authors.initials: S
authors.lastname: Fields
authors.forename: H
authors.initials: H
authors.lastname: Bar-On
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced*; D008297:Male
chemical_list: D000638:Amiodarone