Selective delivery of chemotherapeutic agents with a new catheter system.
A new catheter system was used in ten patients (16 infusions) for infusion of chemotherapeutic agents to the sites of malignant gliomas. Thirteen infusions to the supraophthalmic region were successful, as were three infusions to the posterior cerebral region. There were no complications after the infusions. A neurologic complication occurred in one patient in whom two successful supraophthalmic infusions were previously carried out. In this patient the guide wire separated during catheter placement into the posterior cerebral artery.
Wolpert
S M
SM
Department of Radiology, New England Medical Center Hospital, Boston, MA 02111.
Kwan
E S
ES
Heros
D
D
Kasdon
D L
DL
Hedges
T R
TR
D001932:Brain Neoplasms / Q000188:drug therapy*; D002330:Carmustine / Q000008:administration & dosage* / Q000627:therapeutic use; D002343:Carotid Artery, Internal; D002408:Catheters, Indwelling; D002536:Cerebral Arteries; D005910:Glioma / Q000188:drug therapy*; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000295:instrumentation*
D002330:Carmustine