Comparison trial of clindamycin with aztreonam or gentamicin in the treatment of postpartum endometritis.
Sixty-two patients who had postpartum endometritis were treated with clindamycin in combination with either aztreonam or the aminoglycoside gentamicin. Currently, the combination of clindamycin and an aminoglycoside constitutes a treatment of choice for this condition. Our results suggest that aztreonam can be substituted for an aminoglycoside in the treatment of postpartum endometritis with similar clinical outcomes.
Greenberg
R N
RN
Department of Medicine, Saint Louis University School of Medicine, Missouri.
Reilly
P M
PM
Weinandt
W J
WJ
Wilson
K M
KM
Bollinger
M
M
Ojile
J M
JM
D000293:Adolescent; D000328:Adult; D001398:Aztreonam / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002981:Clindamycin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004359:Drug Therapy, Combination; D004716:Endometritis / Q000188:drug therapy*; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D011247:Pregnancy; D011644:Puerperal Disorders / Q000188:drug therapy*; D011897:Random Allocation
D005839:Gentamicins; D002981:Clindamycin; D001398:Aztreonam