On the evolution of specificity and catalysis in subtilisin.
Wells
J A
JA
Department of Biomolecular Chemistry, Genetech Incorporated, South San Francisco, California 94080.
Cunningham
B C
BC
Graycar
T P
TP
Estell
D A
DA
Carter
P
P
D000595:Amino Acid Sequence; D001407:Bacillus / Q000201:enzymology; D005075:Biological Evolution; D002384:Catalysis; D007700:Kinetics; D008958:Models, Molecular; D011487:Protein Conformation; D012697:Serine Endopeptidases / Q000235:genetics* / Q000378:metabolism; D013045:Species Specificity; D013381:Subtilisins / Q000235:genetics* / Q000378:metabolism
D012697:Serine Endopeptidases; D013381:Subtilisins