Conjunctival oxygen tension monitoring during a controlled phlebotomy.
A decrease in the conjunctival oxygen tension (Pcjo2) and conjunctival index (Pcjo2/Pao2) has been shown to be an early marker of acute blood loss. We sequentially measured Pcjo2, Pcjo2/Pao2, blood pressure, and pulse rate in five healthy adults after controlled phlebotomy of 450 mL and after intravenous fluid repletion. No significant changes occurred in either the Pcjo2 or Pcjo2/Pao2 after phlebotomy or after fluid replacement. We conclude that a blood loss of 450 mL in healthy, euvolemic adults is insufficient to perturb the conjunctival index. The lower limits of sensitivity of changes in Pcjo2 and Pcjo/Pao2 in response to acute blood loss remain to be established.
Klein
M
M
Department of Medicine, York Hospital, PA 17405.
Hess
D
D
Eitel
D
D
Bauernshub
D
D
Sabulsky
N
N
D000328:Adult; D001784:Blood Gas Analysis; D001815:Bloodletting / Q000379:methods*; D003228:Conjunctiva / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure; D011187:Posture; D011674:Pulse
D010100:Oxygen