title: Effect of continuous illumination on secretion of pregnane compounds by the rat ovary.
abstract: Differences in the secretion of pregnane compounds from rats with follicular polycystic ovaries under constant light and with normal preovulatory ovaries under light-dark conditions were compared. The injection of LH greatly increased the secretion of progesterone. 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one, in both types of ovaries, but the response of the two progesterone metabolites in the polycystic ovaries was low, suggesting low 5 alpha-reductase activity.
authors.affiliation: Department of Animal Reproduction, College of Agriculture, University of Osaka Prefecture, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kosaka
authors.forename: T
authors.initials: T
authors.lastname: Sawada
authors.forename: S
authors.initials: S
authors.lastname: Ichikawa
mesh_terms: D000818:Animals; D004971:Estrus / Q000528:radiation effects; D005260:Female; D008027:Light; D007986:Luteinizing Hormone / Q000494:pharmacology; D010053:Ovary / Q000378:metabolism* / Q000473:pathology / Q000528:radiation effects; D011085:Polycystic Ovary Syndrome / Q000473:pathology / Q000503:physiopathology*; D011278:Pregnanes / Q000378:metabolism*; D011374:Progesterone / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D011278:Pregnanes; D011374:Progesterone; D007986:Luteinizing Hormone