title: [Congenital nephrotic syndrome associated with congenital toxoplasmosis].
abstract: The authors report the case of a 1 month-old infant presenting with congenital toxoplasmosis associated with nephrotic syndrome and microscopic hematuria. Percutaneous renal biopsy showed a diffuse mild increase in mesangial cells and matrix, but immunofluorescence was negative. Electron microscopy revealed the presence of extensive fusion of foot processes. A review of the nephropathy of congenital toxoplasmosis is presented. Outcome seems to be favorable under steroid therapy. The pathophysiology of nephropathy is discussed, as well as the relationships or coincidence between congenital toxoplasmosis and nephrotic syndrome.
authors.affiliation: Clinique de Pédiatrie et de Puériculture, American Memorial Hospital, Reims.
authors.forename: B
authors.initials: B
authors.lastname: Roussel
authors.forename: J M
authors.initials: JM
authors.lastname: Pinon
authors.forename: P
authors.initials: P
authors.lastname: Birembaut
authors.forename: J
authors.initials: J
authors.lastname: Rullier
authors.forename: F
authors.initials: F
authors.lastname: Pennaforte
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000473:pathology; D009404:Nephrotic Syndrome / Q000151:congenital* / Q000209:etiology; D014125:Toxoplasmosis, Congenital / Q000150:complications* / Q000503:physiopathology
vernacular_title: Syndrome néphrotique congénital associé à une toxoplasmose congénitale.