Role of the thalamus in language: is it related to schizophrenic thought disorder?
Crosson (1985) proposed a model for language production which integrated cortical with subcortical functions. The implications of this model for schizophrenia are explored. One conclusion is that neural systems, as opposed to a single neural focus, account for schizophrenic symptoms. In this light, data regarding dysfunction in the limbic system, nucleus accumbens, globus pallidus, and prefrontal cortex, which are often seen as contradictory, can be viewed as complementary. Another conclusion is that Crosson's model may have implications specific to schizophrenic thought disorder. Random triggering of semantic segments and inability to maintain contextual referents are discussed in the context of the language production theory.
Crosson
B
B
Irene Walter Johnson Rehabilitation Institute, Washington University Medical Center, St. Louis, MO 63110.
Hughes
C W
CW
D001931:Brain Mapping; D004298:Dopamine / Q000502:physiology; D006801:Humans; D012559:Schizophrenia / Q000503:physiopathology*; D012564:Schizophrenic Language; D012565:Schizophrenic Psychology; D013787:Thalamic Nuclei / Q000503:physiopathology*; D013850:Thinking / Q000502:physiology*
D004298:Dopamine