title: [Significance of polyamines for the early diagnosis of spontaneous hemoblastoses in AKR mice].
abstract: Polyamines levels were studied in various tissue specimens obtained from high-leukemia AKR mice aged 12 months and less. Organ tissues of leukemic animals revealed increased levels of polyamines and changes in their profile. In symptomatic mice, this was matched by relevant morphologic changes. It is inferred that putrescine is a marker of latent leukemia development.
authors.forename: L D
authors.initials: LD
authors.lastname: Voronchikhina
authors.forename: S I
authors.initials: SI
authors.lastname: Vorozhtsova
authors.forename: V N
authors.initials: VN
authors.lastname: Minakov
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Zinov'ev
authors.forename: T P
authors.initials: TP
authors.lastname: Shkanakina
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor; D001923:Brain Chemistry; D005260:Female; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008223:Lymphoma / Q000378:metabolism*; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D011073:Polyamines / Q000096:biosynthesis*; D011700:Putrescine / Q000096:biosynthesis; D013095:Spermidine / Q000096:biosynthesis; D013096:Spermine / Q000096:biosynthesis; D013154:Spleen / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D011073:Polyamines; D013096:Spermine; D013095:Spermidine; D011700:Putrescine
vernacular_title: Znachenie poliaminov dlia ranneĭ diagnostiki spontannykh gemoblastozov mysheĭ AKR.