[Characteristics of the ultrastructural organization of the nuclei of somatic cell hybrids].
A study was made of the ultrastructure of cell nuclei of two types of hybrid clones obtained from the fusion of Chinese hamster with human skin fibroblasts, and from that of mouse hepatoma cells with mink fibroblasts. In cell nuclei of the eight hybrid clones deep invaginations of the inner membrane, not characteristic of the parent cells, were revealed. Analysis of serial sections, and application of electron microscopic radioautography and histochemistry have suggested that these structures are associated with the nuclear envelope which is necessary for regulating the superfluous chromosome localization in the hybrid nucleus.
Kerkis
A Iu
AIu
Kazanskaia
G M
GM
Zhdanova
N S
NS
Khristoliubova
N B
NB
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure*; D002843:Chromatin / Q000648:ultrastructure; D006224:Cricetinae; D003584:Cytological Techniques; D006801:Humans; D006822:Hybrid Cells / Q000648:ultrastructure*; D008114:Liver Neoplasms, Experimental / Q000648:ultrastructure; D051379:Mice; D008854:Microscopy, Electron; D008907:Mink
D002843:Chromatin
Osobennosti ul'trastrukturnoĭ organizatsii iader gibridov somaticheskikh kletok.