The antioxidative properties of carnosine, a natural histidine containing dipeptide.
The experimental results suggest that the antioxidative function of carnosine is one of the most important manifestations of its biological role. The ability of carnosine to interact directly with lipid peroxidation products was demonstrated. The effects of carnosine on partial restoration of lens transparency in dog eyes with senile cataract which is known to be caused by lipid peroxidation were demonstrated "in vitro" and "in vivo".
Boldyrev
A A
AA
Department of Biochemistry, Moscow State University, USSR.
Dupin
A M
AM
Bunin AYa
Babizhaev
M A
MA
Severin
S E
SE
D000818:Animals; D000975:Antioxidants; D002336:Carnosine / Q000502:physiology*; D002386:Cataract / Q000503:physiopathology; D004151:Dipeptides / Q000502:physiology*; D005978:Glutathione / Q000502:physiology; D006801:Humans; D007908:Lens, Crystalline / Q000502:physiology
D000975:Antioxidants; D004151:Dipeptides; D002336:Carnosine; D005978:Glutathione