title: Thrombocytopenia: a complication of Kawasaki disease.
abstract: Thrombocytopenia was observed in 10 (2.0%) of 486 children with Kawasaki disease. In nine of the ten, the minimal platelet count of 94,000 +/- 38,000 (SD)/mm3 was seen on day 6.8 +/- 2.2 (SD) of illness and the platelet counts were elevated to the normal level in 1-2 weeks. Thrombocytopenia in the nine appeared to be caused via coagulation-mediated platelet consumption, while the remaining child was diagnosed as having idiopathic thrombocytopenic purpura. One of the two who had severe coagulation-mediated thrombocytopenia of less than 50,000/mm3 developed coronary aneurysms persisting over 1 year.
authors.affiliation: Department of Paediatrics, Faculty of Medicine, Kyushu University, Fukuoka city, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hara
authors.forename: Y
authors.initials: Y
authors.lastname: Mizuno
authors.forename: H
authors.initials: H
authors.lastname: Akeda
authors.forename: J
authors.initials: J
authors.lastname: Fukushige
authors.forename: K
authors.initials: K
authors.lastname: Ueda
authors.forename: T
authors.initials: T
authors.lastname: Aoki
authors.forename: H
authors.initials: H
authors.lastname: Sunagawa
authors.forename: S
authors.initials: S
authors.lastname: Honda
authors.forename: T
authors.initials: T
authors.lastname: Hijii
authors.forename: Y
authors.initials: Y
authors.lastname: Yamaguchi
mesh_terms: D001241:Aspirin / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003323:Coronary Aneurysm / Q000209:etiology; D005260:Female; D005480:Flurbiprofen / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D008499:Medical Records; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications* / Q000188:drug therapy; D010976:Platelet Count; D013921:Thrombocytopenia / Q000209:etiology*
chemical_list: D005480:Flurbiprofen; D001241:Aspirin