title: The single-patient clinical trial.
abstract: A single-patient clinical trial is useful in helping the physician decide whether a specific treatment is helpful or harmful in a specific case. The patient's problem must be chronic and stable, and there must be a clearly measurable end point. The close cooperation of the patient, the nurse and the pharmacist is required. In a situation that meets these prerequisites, a properly performed and analyzed single-patient study may be of great benefit.
authors.affiliation: University of Illinois College of Medicine at Peoria.
authors.forename: M A
authors.initials: MA
authors.lastname: Frasca
authors.forename: J C
authors.initials: JC
authors.lastname: Aldag
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods*; D004311:Double-Blind Method; D006801:Humans; D010919:Placebos
chemical_list: D010919:Placebos