title: Renal and urinary tract abnormalities associated with chromosome aberrations.
abstract: The frequency of malformations of the kidney and urinary tract is much higher in patients with chromosome aberrations than in the general population. Sixty to 100% of "cat-eye" syndrome, 60 to 80% of Turner, 75% of trisomy 8, 33 to 70% of trisomy 18, 50 to 60% of trisomy 13, and over 50% of triploidy and tetraploidy patients may have such abnormalities. Renal and urinary tract malformations should be looked for in all patients with chromosome aberrations. Moreover, a chromosome study is indicated in any fetus with an ultrasonographic evidence of urinary tract abnormality.
authors.affiliation: Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee.
authors.forename: A Y
authors.initials: AY
authors.lastname: Barakat
authors.forename: M G
authors.initials: MG
authors.lastname: Butler
mesh_terms: D002869:Chromosome Aberrations; D006801:Humans; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities*; D008297:Male; D009006:Monosomy; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014314:Trisomy; D014551:Urinary Tract / Q000002:abnormalities*