Normal pregnancy and delivery two years after adjuvant chemotherapy for grade III immature ovarian teratoma.
A 27-year-old woman with grade 3 immature teratoma of the ovary was treated with unilateral salpingo-oophorectomy and VAC combination chemotherapy. She received 6 postoperative courses, although initially 12 were planned. Chemotherapy had to be discontinued because of severe bone marrow toxicity. Eighteen months later the patient became pregnant and was ultimately delivered of a normal child. This is the second report of a successful pregnancy following VAC chemotherapy for immature teratoma.
Schneider
J
J
Department of Obstetrics and Gynecology, Hospital Nacional Valdecilla, Santander, Spain.
Erasun
F
F
Hervas
J L
JL
Acinas
O
O
Gonzalez-Rodilla
I
I
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D011247:Pregnancy; D013724:Teratoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D013997:Time Factors; D014750:Vincristine / Q000008:administration & dosage
D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide