title: Vertebral bone density in children: effect of puberty.
abstract: To determine changes in bone density during growth, trabecular vertebral density and an index of spinal cortical bone were measured with quantitative computed tomography in 101 children. The children were divided by age into three groups: prepubertal, indeterminate, and pubertal. Compared with prepubertal children, pubertal adolescents had significantly higher trabecular bone density and more compact bone in the spine (P less than .001). After controlling for puberty, vertebral bone density failed to correlate significantly with age, sex, weight, height, surface area, and body mass index. The results indicate that bone density increases markedly during puberty.
authors.affiliation: Department of Radiology, Childrens Hospital of Los Angeles, CA 90064-0700.
authors.forename: V
authors.initials: V
authors.lastname: Gilsanz
authors.forename: D T
authors.initials: DT
authors.lastname: Gibbens
authors.forename: T F
authors.initials: TF
authors.lastname: Roe
authors.forename: M
authors.initials: M
authors.lastname: Carlson
authors.forename: M O
authors.initials: MO
authors.lastname: Senac
authors.forename: M I
authors.initials: MI
authors.lastname: Boechat
authors.forename: H K
authors.initials: HK
authors.lastname: Huang
authors.forename: E E
authors.initials: EE
authors.lastname: Schulz
authors.forename: C R
authors.initials: CR
authors.lastname: Libanati
authors.forename: C C
authors.initials: CC
authors.lastname: Cann
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011627:Puberty; D013131:Spine / Q000033:anatomy & histology* / Q000254:growth & development