title: Contemporary insights into the regulation of luteinizing hormone secretion in man.
abstract: Recent advances in clinical investigative techniques have now permitted the delineation of a spectrum of distinct pathophysiological disorders of gonadotropin secretion in the human, and have suggested important therapeutic avenues for the treatment of clinical hypogonadism in men and women. Advances have occurred in part in the arena of methodology with a broader assessment of the full physiological spectrum of pulsatile gonadotropin secretion, and in part in the use of more refined and selective pharmacological tools to investigate the neuroendocrine facets of gonadotropin dynamics.
authors.affiliation: Division of Endocrinology and Metabolism, University of Virginia School of Medicine, Charlottesville, Va.
authors.forename: J D
authors.initials: JD
authors.lastname: Veldhuis
mesh_terms: D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology / Q000502:physiology; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D008297:Male
chemical_list: D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone