T cell-depleted allogeneic bone marrow transplantation in a case of childhood idiopathic myelofibrosis.
An 11-year-old boy developed primary myelofibrosis. Nine months after diagnosis he received high-dose chemoradiotherapy followed by T cell-depleted allogeneic bone marrow transplantation as primary therapy. Sixteen months after grafting the patient is well, with reversal of the marrow sclerosis and no evidence of chronic graft-versus-host disease.
Cahn
J Y
JY
Bone Marrow Transplant Unit, Besançon, France.
Plouvier
E
E
Flesch
M
M
Carbillet
J P
JP
Herve
P
P
D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002648:Child; D002678:Chimera; D003114:Colony-Forming Units Assay; D006412:Hematopoietic Stem Cells / Q000166:cytology; D006801:Humans; D008297:Male; D055728:Primary Myelofibrosis / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology*