Comparison of a lactose-free cereal-based formula and cow's milk in infants and children with acute gastroenteritis.
Sixty children less than 2 years of age suffering from mild acute gastroenteritis with less than 5% dehydration were randomly assigned to two different isocaloric feeding regimens, viz., a locally prepared milk-free formulation (group A) of rice, lentil, sugar, and coconut oil and a spray dried commercial cow's milk formula (group B). There were two treatment failures in group A and one in group B. The postintervention duration of diarrhea (days) in group A (11.0 +/- 10.0) was higher than in group B (7.6 +/- 10.8), but these differences were not significant (p greater than 0.05). The energy intake (kcal/kg/24 h) on postintervention day 4 was 78.7 +/- 31.7 in group A and 101.3 +/- 41.1 in group B (p greater than 0.05). The corresponding values for day 7 were 74.2 +/- 29.1 and 110.0 +/- 41.1, respectively (p less than 0.05). The mean weight gain (g/kg/24 h) between admission and the day of recovery in group A (2.0 +/- 4.2) was significantly lower (p less than 0.05) than in group B (5.8 +/- 7.8). Similar trends in weight gain were observed at days 4 and 7. These findings suggest that a cow's milk-based formula is well tolerated by majority of the infants with mild acute gastroenteritis after initial rehydration with ORS. The infants who were fed the milk-free cereal-based diet showed significantly less energy intake and gained weight less rapidly than those who were fed the cow's milk-based formula.
Bhan
M K
MK
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi.
Arora
N K
NK
Khoshoo
V
V
Raj
P
P
Bhatnager
S
S
Sazawal
S
S
Sharma
K
K
D000818:Animals; D001835:Body Weight; D003681:Dehydration / Q000628:therapy*; D002523:Edible Grain; D002149:Energy Intake; D005440:Fluid Therapy; D005759:Gastroenteritis / Q000628:therapy*; D006801:Humans; D007223:Infant; D007225:Infant Food; D007785:Lactose; D008892:Milk; D011897:Random Allocation
D007785:Lactose