title: Muscle atrophy and leg length discrepancies in pauciarticular juvenile rheumatoid arthritis.
abstract: In 32 children with pauciarticular juvenile rheumatoid arthritis, we studied residual muscle atrophy and leg length discrepancy after the arthritis had entered remission. Children under the age of 3 years at disease onset had significantly more muscle atrophy and bone overgrowth than children whose disease began after the age of 3 years. These residua have cosmetic and functional significance, and new methods of treatment will be necessary to prevent or reverse the sequelae in a form of arthritis previously thought to have a benign outcome.
authors.affiliation: National Jewish Center for Immunology and Respiratory Medicine, Denver, CO 80206.
authors.forename: M
authors.initials: M
authors.lastname: Vostrejs
authors.forename: J R
authors.initials: JR
authors.lastname: Hollister
mesh_terms: D000367:Age Factors; D001171:Arthritis, Juvenile / Q000150:complications*; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D007870:Leg Length Inequality / Q000209:etiology*; D008297:Male; D009133:Muscular Atrophy / Q000209:etiology* / Q000628:therapy; D026741:Physical Therapy Modalities