Triad of hypopituitarism, granulomatous hypophysitis, and ruptured Rathke's cleft cyst.
A 19-year-old girl with pituitary insufficiency and a large sella turcica was found to have granulomatous hypophysitis in association with a Rathke's cleft cyst. We think that the inflammatory process represents a foreign body reaction to leakage of cyst contents, with destruction of pituitary tissue.
Albini
C H
CH
Department of Pediatrics, Children's Hospital of Buffalo, State University of New York.
MacGillivray
M H
MH
Fisher
J E
JE
Voorhess
M L
ML
Klein
D M
DM
D000328:Adult; D003397:Craniopharyngioma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D007249:Inflammation; D010900:Pituitary Diseases / Q000209:etiology*; D010911:Pituitary Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D012422:Rupture, Spontaneous; D014057:Tomography, X-Ray Computed