In vitro model systems permitting the analysis of the differentiation of mammalian progenitor cells either into neurons or into glial cells.
The peripheral nervous system, including both neurons and Schwann cells, is derived almost entirely from the neural crest. We described here the use of the migratory properties of mouse neural crest cells and chemically defined conditions to differentiate them in vitro into neuronal derivatives.
Simonneau
M
M
Laboratoire de Neurobiologie Cellulaire et Moléculaire, CNRS, Gif-sur-Yvette.
Boisseau
S
S
Valmier
J
J
Poujeol
C
C
D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D051379:Mice; D009432:Neural Crest / Q000166:cytology*; D009457:Neuroglia / Q000166:cytology*; D009474:Neurons / Q000166:cytology*; D051381:Rats