title: Paget's disease: a cause of photopenic skeletal defect in indium-111 WBC scintigraphy.
abstract: As an incidental finding in an [111In]WBC scan performed in search of an infectious focus, photon deficient areas were found in several skeletal locations, characterized by bone and gallium scintigraphy and confirmed radiographically as sites of active Paget's disease. The literature concerning cold bone defects in the [111In]WBC scintiscan is reviewed. Loss of marrow component in the bone appears to be the underlying mechanism for such an abnormality.
authors.affiliation: Department of Radiology, SUNY Health Science Center, Brooklyn 11203.
authors.forename: E K
authors.initials: EK
authors.lastname: Dunn
authors.forename: R A
authors.initials: RA
authors.lastname: Vaquer
authors.forename: A M
authors.initials: AM
authors.lastname: Strashun
mesh_terms: D000368:Aged; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D006801:Humans; D007205:Indium Radioisotopes; D007962:Leukocytes; D008297:Male; D010001:Osteitis Deformans / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging
chemical_list: D007205:Indium Radioisotopes