Iron and immunologic function.
This short review focuses on the immunological functions of iron-containing compounds. Five such compounds--transferrin, haptoglobin, hemopexin, albumin, and lactoferrin--are thought to contribute to normal infection resistance. Experimental results that demonstrate the ability of these compounds to inhibit the growth of an important pathogen, Klebsiella pneumoniae, are discussed.
Ward
C G
CG
University of Miami School of Medicine, Florida.
D000418:Albumins / Q000378:metabolism; D002056:Burns / Q000150:complications; D006242:Haptoglobins / Q000378:metabolism; D006466:Hemopexin / Q000378:metabolism; D006801:Humans; D007109:Immunity; D007501:Iron / Q000502:physiology*; D007711:Klebsiella pneumoniae / Q000276:immunology; D007781:Lactoferrin / Q000378:metabolism; D011485:Protein Binding; D014168:Transferrin / Q000378:metabolism; D014946:Wound Infection / Q000276:immunology
D000418:Albumins; D006242:Haptoglobins; D014168:Transferrin; D006466:Hemopexin; D007501:Iron; D007781:Lactoferrin