The confirmation of norethindrone aromatization in primary human hepatocytes by the Vitafiber-II cell culture system.
A portion of norethindrone (17 alpha-ethynyl-19-nortestosterone) was confirmed to be aromatized to ethynyl estradiol (17 alpha-ethynyl estradiol) in primary human hepatocytes cultured using the Vitafiber-II cell culture system.
Yamamoto
T
T
Department of Obstetrics and Gynecology, Kyoto Prefectural University of Medicine.
Kitawaki
J
J
Shiroshita
K
K
Urabe
M
M
Sasaki
J
J
Fukuoka
M
M
Naitoh
K
K
Honjo
H
H
Okada
H
H
D000818:Animals; D001141:Aromatase / Q000378:metabolism; D002478:Cells, Cultured; D003470:Culture Media; D004997:Ethinyl Estradiol / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D009640:Norethindrone / Q000378:metabolism*; D011817:Rabbits
D003470:Culture Media; D004997:Ethinyl Estradiol; D001141:Aromatase; D009640:Norethindrone