Serum levels of vitamin A, E, and selenium in women with lichen sclerosus of the vulva treated with etretinate.
Forty-six patients with Lichen sclerosus (Ls) of the vulva were treated with peroral etretinate for 3 months. The pretreatment serum levels of vitamins A and E, and selenium were measured. Etretinate therapy proved to be effective in the treatment of Ls; however, it did not affect the vitamin A status of the Ls patients. Vitamin E and selenium levels did not differ from the control values, nor did they have any prognostic value.
Romppanen
U
U
Tampere University Central Hospital, Department of Obstetrics and Gynaecology, Finland.
Tuimala
R
R
Ellmén
J
J
Koskinen
T
T
Pyykkö
K
K
D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D012016:Reference Values; D012598:Sclerosis; D012643:Selenium / Q000097:blood*; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*; D014844:Vulva / Q000473:pathology; D014845:Vulvar Diseases / Q000097:blood / Q000188:drug therapy* / Q000473:pathology
D014801:Vitamin A; D014810:Vitamin E; D005050:Etretinate; D012643:Selenium