Detection of carcinoma in the post-cystectomy urethral remnant by flow cytometric analysis.
Following radical cystoprostatectomy for bladder cancer patients must be monitored for carcinoma of the urethral remnant. Cytological examination of urethral washings has proved to be a useful alternative to urethroscopy and urethrography. Urethral irrigation specimens also can be evaluated objectively by flow cytometry. In each of 4 patients in whom carcinoma developed in the urethral remnant analysis of urethral irrigation by flow cytometry was positive and comparable to results of urethral irrigation cytology. Flow cytometry is an objective and apparently reliable diagnostic test for malignancy in the urethral remnant.
Hermansen
D K
DK
Department of Surgery (Urologic Service), Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
Badalament
R A
RA
Whitmore
W F
WF
Fair
W R
WR
Melamed
M R
MR
D000368:Aged; D002277:Carcinoma / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000473:pathology; D004273:DNA, Neoplasm / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D011468:Prostatectomy; D014523:Urethral Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D001743:Urinary Bladder / Q000601:surgery*; D001749:Urinary Bladder Neoplasms / Q000601:surgery*
D004273:DNA, Neoplasm