title: Exploration of acid gastroesophageal reflux by 24-h pH metry in infants at risk of sudden infant death syndrome: a study of 50 cases.
abstract: This study focused on the frequency of pathological acid gastroesophageal reflux (AGER) on 50 children considered to be at risk for sudden infant death syndrome: that is to say, 30 near misses and 20 subsequent siblings. Four parameters were studied in a 24-h pH metry: (1) The percentage of time spent at pH less than 4. (2) The length of the longest reflux. (3) The number of refluxes greater than 5 min/h. (4) Esophageal clearance. In comparison to a control group of 46 normal children, we noted a rate of 20% of AGER on the near misses and 31% on children whose siblings had died from sudden infant death syndrome. The pH level of these two groups was significantly more often less than 4, compared to the normal children. The role of AGER in sudden infant death syndrome will, therefore, be discussed.
authors.affiliation: Service de Médecine Interne, C.H.R. Morvan, Brest, France.
authors.forename: E
authors.initials: E
authors.lastname: Baccino
authors.forename: D
authors.initials: D
authors.lastname: Le Goff
authors.forename: G
authors.initials: G
authors.lastname: Lancien
authors.forename: M
authors.initials: M
authors.lastname: Le Guillou
authors.forename: D
authors.initials: D
authors.lastname: Alix
authors.forename: D
authors.initials: D
authors.lastname: Mottier
mesh_terms: D005764:Gastroesophageal Reflux / Q000150:complications*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008991:Monitoring, Physiologic; D011446:Prospective Studies; D012307:Risk Factors; D013398:Sudden Infant Death / Q000209:etiology*