A new pathway for phosphatidylserine synthesis in rat liver microsomes.
It has been shown that the phosphate moiety of glycerophosphate is incorporated into phosphatidylserine of rat liver microsomes, but not of mitochondria. The reaction is dependent on CMP. This observation suggests that the new pathway of acyl-specific synthesis of phosphatidylserine proposed by J.P. Infante [(1984) FEBS Lett. 170, 1-14] can proceed in rat liver microsomes.
Baranska
J
J
Department of Cellular Biochemistry, Nencki Institute of Experimental Biology, Warszawa, Poland.
D000345:Affinity Labels; D000818:Animals; D005994:Glycerophosphates / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000378:metabolism; D010718:Phosphatidylserines / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains
D000345:Affinity Labels; D005994:Glycerophosphates; D010718:Phosphatidylserines