title: Benign lymphocytic angiitis and granulomatosis: experience with three cases.
abstract: Of three patients with lung-biopsy-proven benign lymphocytic angiitis and granulomatosis, two experienced complete resolution of their disease from therapy with chlorambucil and one underwent spontaneous remission with no drug therapy after lung biopsy and removal of a benign spindle cell thymoma. Clinically, it is difficult to determine whether benign lymphocytic angiitis is a low-grade (prelymphomatous) lymphoma or a vasculitis. Its position in this spectrum of diseases is uncertain. Nonetheless, benign lymphocytic angiitis and granulomatosis corresponding to a low-grade angiocentric immunoproliferative lesion is a clinicopathologically useful concept.
authors.affiliation: Division of Thoracic Diseases and Internal Medicine, Mayo Clinic, Rochester, MN 55905.
authors.forename: D R
authors.initials: DR
authors.lastname: Gracey
authors.forename: R A
authors.initials: RA
authors.lastname: DeRemee
authors.forename: T V
authors.initials: TV
authors.lastname: Colby
authors.forename: K K
authors.initials: KK
authors.lastname: Unni
authors.forename: L H
authors.initials: LH
authors.lastname: Weiland
mesh_terms: D000368:Aged; D002699:Chlorambucil / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008230:Lymphomatoid Granulomatosis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D008875:Middle Aged; D011230:Precancerous Conditions / Q000175:diagnosis; D012075:Remission, Spontaneous; D014657:Vasculitis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology
chemical_list: D002699:Chlorambucil