title: Temporal pattern of alcohol dehydrogenase gene transcription reproduced by Drosophila stage-specific embryonic extracts.
abstract: Regulation of transcription during development has been analysed in vitro using extracts derived from Drosophila embryos. Transcription of mutant templates reveals cis-control regions of the alcohol dehydrogenase promoter responsible for temporal regulation. The activity of a trans-acting protein correlates with the profile of alcohol dehydrogenase expression during embryogenesis.
authors.affiliation: Howard Hughes Medical Institute, Department of Biochemistry, University of California, Berkeley 94720.
authors.forename: U
authors.initials: U
authors.lastname: Heberlein
authors.forename: R
authors.initials: R
authors.lastname: Tjian
mesh_terms: D000426:Alcohol Dehydrogenase / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D004330:Drosophila / Q000196:embryology / Q000235:genetics; D005786:Gene Expression Regulation; D011401:Promoter Regions, Genetic; D014158:Transcription, Genetic
chemical_list: D000426:Alcohol Dehydrogenase