Accidental actinomycin D overdosage in man, a case report.
Although actinomycin D is a relatively old cytotoxic agent, relatively little is known about its toxicity in man in comparison with some of the newer cytotoxic agents that have been extensively investigated. We wish to describe a case where an overdose of actinomycin D was inadvertently administered.
Choonara
I A
IA
Department of Paediatrics and Child Health, St. James's University Hospital, Leeds, England.
Kendall-Smith
S
S
Bailey
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CC
D000293:Adolescent; D056486:Chemical and Drug Induced Liver Injury; D003609:Dactinomycin / Q000506:poisoning*; D003967:Diarrhea / Q000139:chemically induced; D004487:Edema / Q000139:chemically induced; D004573:Electrolytes / Q000097:blood; D004890:Erythema / Q000139:chemically induced; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects; D008274:Magnesium / Q000652:urine; D008297:Male; D009061:Mouth Mucosa; D012640:Seizures / Q000139:chemically induced; D013280:Stomatitis / Q000139:chemically induced
D004573:Electrolytes; D003609:Dactinomycin; D008274:Magnesium