title: Prevention of iron deficiency by milk fortification. II. A field trial with a full-fat acidified milk.
abstract: In a longitudinal study from age 3 to 15 mo, 276 term, healthy, spontaneously weaned infants received a full-fat acidified milk fortified with 15 mg of elemental Fe as ferrous sulfate and 100 mg of ascorbic acid/100 g of powder and 278 control infants received milk without additives. At ages 9 and 15 mo significant differences were encountered in all measures of Fe nutriture in favor of the fortified group (p less than 0.001). Anemia (Hg less than 110 g/L) was present in 25.7% of unfortified infants compared with only 2.5% in those fortified at age 15 mo. Saturation of transferrin less than 9% was present in 33.8% and serum ferritin less than 10 micrograms/L in 39.1% of the nonfortified infants. The figures for the fortified group were 7 and 8.5% respectively. The efficiency of the fortified acidified milk in eradicating Fe deficiency in the infants while discouraging use by other family members make this milk a useful targeted product in programs of supplementary food distribution in the underdeveloped world.
authors.affiliation: Institute of Nutrition and Food Technology, University of Chile, Santiago.
authors.forename: A
authors.initials: A
authors.lastname: Stekel
authors.forename: M
authors.initials: M
authors.lastname: Olivares
authors.forename: M
authors.initials: M
authors.lastname: Cayazzo
authors.forename: P
authors.initials: P
authors.lastname: Chadud
authors.forename: S
authors.initials: S
authors.lastname: Llaguno
authors.forename: F
authors.initials: F
authors.lastname: Pizarro
mesh_terms: D000747:Anemia, Hypochromic / Q000097:blood / Q000517:prevention & control*; D000818:Animals; D002677:Chile; D005069:Evaluation Studies as Topic; D005260:Female; D005527:Food, Fortified; D006801:Humans; D007223:Infant; D007225:Infant Food; D008137:Longitudinal Studies; D008297:Male; D008892:Milk; D011897:Random Allocation; D012959:Socioeconomic Factors; D014505:Urban Population