Follow-up study of control subjects with lactate- and isoproterenol-induced panic attacks.
Eleven of 45 normal control subjects experienced panic attacks during lactate and/or isoproterenol infusions. Ten of the 11 subjects were followed up for a mean period of 32.5 months. Two subjects reported the development of spontaneous panic attacks during the follow-up period; one related the development of these attacks to the infusion experience. Neither subject met DSM-III criteria for panic disorder either before or after the infusions. Twenty-six healthy control subjects who did not experience panic attacks during the infusion experience did not report any attacks during a follow-up period of 31.1 months.
Balon
R
R
Lafayette Clinic, Detroit, MI 48207.
Pohl
R
R
Yeragani
V K
VK
Rainey
J M
JM
Berchou
R
R
D000328:Adult; D001008:Anxiety Disorders / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D005239:Fear; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D007545:Isoproterenol / Q000008:administration & dosage; D007773:Lactates / Q000008:administration & dosage; D019344:Lactic Acid; D008297:Male; D008370:Manuals as Topic; D010200:Panic
D007773:Lactates; D019344:Lactic Acid; D007545:Isoproterenol