Fatality secondary to misuse of TAC solution.
The death of a 7 1/2-month-old girl from the misuse of tetracaine/adrenalin/cocaine solution for wound anesthesia is reported. Ten milliliters of the solution inappropriately came into contact with nasal mucous membranes, causing excessive drug absorption. The patient's death probably was due to cocaine toxicity (post-mortem blood level, 11.9 mg/L).
Dailey
R H
RH
Department of Emergency Medicine, Highland General Hospital, Oakland, California 94602.
D000779:Anesthetics, Local / Q000493:pharmacokinetics / Q000506:poisoning*; D003042:Cocaine / Q000493:pharmacokinetics / Q000506:poisoning*; D004338:Drug Combinations / Q000493:pharmacokinetics / Q000506:poisoning; D004837:Epinephrine / Q000493:pharmacokinetics / Q000506:poisoning*; D005260:Female; D006801:Humans; D007223:Infant; D008046:Lip / Q000293:injuries; D009297:Nasal Mucosa / Q000378:metabolism; D013748:Tetracaine / Q000493:pharmacokinetics / Q000506:poisoning*
D000779:Anesthetics, Local; D004338:Drug Combinations; D013748:Tetracaine; C034627:TEC solution; D003042:Cocaine; D004837:Epinephrine