title: Carcinoma of penis treated with neodymium YAG laser.
abstract: Sixteen men with squamous cell carcinoma of the penis were treated primarily with the Neodymium Yttrium Aluminum Garnet (Nd:YAG) laser. Five patients had TIS, 9 had T1 tumors, and 2 had T2 carcinoma. All patients had refused traditional therapy of partial penectomy and gave informed consent as to the investigational nature of the Nd:YAG laser photoradiation therapy. Circumcisions and deep tissue biopsies were performed on all patients prior to tumoricidal neodymium photoradiation treatment. The patients were followed from twelve to thirty-six months. At follow-up, 5 patients with TIS had no evidence of recurrent cancer. Of the 9 patients with T1 squamous cell carcinoma of the penis, 6 (67%) were tumor-free at a mean follow-up of twenty-six months. The 2 men with T2 carcinoma of the penis had reduction of the tumor mass but were not cured. The obvious advantage of the Nd:YAG laser in treating carcinoma of the penis is preservation of the penis eliminating disfiguring amputation.
authors.affiliation: Department of Urology, University of Pennsylvania, Philadelphia.
authors.forename: T R
authors.initials: TR
authors.lastname: Malloy
authors.forename: A J
authors.initials: AJ
authors.lastname: Wein
authors.forename: V L
authors.initials: VL
authors.lastname: Carpiniello
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D006801:Humans; D053685:Laser Therapy; D008297:Male; D010412:Penile Neoplasms / Q000628:therapy*; D010789:Phototherapy