title: Collisional spectroscopy as a screening procedure for the determination of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole from acid hydrolysis of B-poly(L-lysine) and B-albumin.
abstract: The direct determination of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI), present in the acid hydrolysis products of B-poly(L-lysine) and B-albumin and which appears to be a key intermediate in the physicochemical changes occurring during the incubation of protein with glucose, has been carried out by collisional spectroscopy, using a commercial double-focusing, reverse-geometry mass spectrometer and without any sample derivatization and chromatographic separation procedures.
authors.affiliation: CNR, Area di Ricerca, Padova, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Pelli
authors.forename: A
authors.initials: A
authors.lastname: Sturaro
authors.forename: P
authors.initials: P
authors.lastname: Traldi
authors.forename: A
authors.initials: A
authors.lastname: Lapolla
authors.forename: T
authors.initials: T
authors.lastname: Poli
authors.forename: D
authors.initials: D
authors.lastname: Fedele
authors.forename: G
authors.initials: G
authors.lastname: Crepaldi
mesh_terms: D000418:Albumins; D003116:Color; D006031:Glycosylation; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007093:Imidazoles / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods; D011107:Polylysine
chemical_list: D000418:Albumins; D007093:Imidazoles; D011107:Polylysine; C041306:2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole