title: Isoflurane and primary pulmonary hypertension.
abstract: Primary pulmonary hypertension is a rare and fatal disease. These patients represent an anaesthetic challenge because of the high mortality associated with the marked intra-operative increase in pulmonary vascular resistance and right ventricular decompensation. This is a first case report which demonstrates the safe and beneficial effects of isoflurane in lowering pulmonary arterial pressure and pulmonary vascular resistance in such a patient for a short surgical procedure. The anaesthetic considerations in these patients are discussed.
authors.affiliation: Department of Anaesthesia, Mount Sinai Hospital, University of Toronto, Ontario, Canada.
authors.forename: D C
authors.initials: DC
authors.lastname: Cheng
authors.forename: G
authors.initials: G
authors.lastname: Edelist
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D001706:Biopsy / Q000379:methods; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000503:physiopathology; D007530:Isoflurane; D008168:Lung / Q000473:pathology / Q000601:surgery*; D008297:Male; D011652:Pulmonary Circulation / Q000187:drug effects
chemical_list: D007530:Isoflurane