[Therapy of pancreatogenic steatorrhea. Comparison of 2 acid-protected enzyme preparations].
In an open, randomised cross-over trial nine patients with severe exocrine pancreatic insufficiency and considerable steatorrhea (greater than 25 g fecal fat excretion daily) received for five days, after a treatment-free period of three days, two new acid-protected enzyme preparations: Kreon, three times six capsules daily, pellets of 1-2 mm diameter; Panzytrat 20.000, three times three capsules daily, microtablets of 2 mm diameter. Both preparations significantly decreased fecal weight and fecal fat excretion. With equivalent lipase dosage there was no difference in effect between the two preparations.
Lankisch
P G
PG
Medizinische Abteilung, Städtisches Krankenhaus Lüneburg.
Lembcke
B
B
Kirchhoff
S
S
Hilgers
R
R
Creutzfeldt
W
W
D000328:Adult; D000437:Alcoholism / Q000150:complications; D002446:Celiac Disease / Q000188:drug therapy* / Q000209:etiology; D010188:Exocrine Pancreatic Insufficiency / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D010184:Pancreatic Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D010194:Pancreatin / Q000008:administration & dosage / Q000627:therapeutic use*
D010184:Pancreatic Extracts; D010194:Pancreatin
Therapie der pankreatogenen Steatorrhoe. Vergleich zweier säuregeschützter Enzympräparate.