[Fibrinolytic activity of natural variants of Bacillus mesentericus].
The natural variability of the ability to synthesize proteinases by Bacillus mesentericus 64 was studied. The population of this strain was shown to be heterogeneous. Three types of variants (S, M and P) differed in the morphology of their colonies and in the culture characteristics from the typical colonies of the parent strain. The caseinolytic activity of the M variant was three times as high as that of the parent strain, and it also had an elevated fibrinolytic activity and a high rate of blood thrombolysis in experiments in vitro. The rate of proteinase synthesis correlated with the morphological types of sporogenic bacteria.
Imshenetskiĭ
A A
AA
Cherkesova
G V
GV
Kasatkina
I D
ID
Nesterova
N G
NG
Fetisova
Z S
ZS
D001407:Bacillus / Q000201:enzymology*; D002364:Caseins / Q000378:metabolism; D003470:Culture Media / Q000378:metabolism; D005337:Fibrin / Q000378:metabolism; D005342:Fibrinolysis / Q000187:drug effects*; D014644:Genetic Variation; D010447:Peptide Hydrolases / Q000096:biosynthesis / Q000494:pharmacology*
D002364:Caseins; D003470:Culture Media; D005337:Fibrin; D010447:Peptide Hydrolases
O fibrinoliticheskoĭ aktivnosti estestvennykh variantov Bacillus mesentericus.