title: Complementary addressed modification of double-stranded DNA within a ternary complex.
abstract: Double-stranded DNA containing a d(pG)18.d(pC)18 sequence was shown to be selectively alkylated in the vicinity of this fragment using the 5'-p-(N-2-chloroethyl-N-methylamino)benzylamide of deoxyribooligocytidylate, CIRCH2NH(pdC)n (n = 9,15), in conditions favouring triple-stranded complex formation.
authors.affiliation: Institute of Bioorganic Chemistry, Siberian Division of the USSR Academy of Sciences, Novosibirsk.
authors.forename: O S
authors.initials: OS
authors.lastname: Fedorova
authors.forename: D G
authors.initials: DG
authors.lastname: Knorre
authors.forename: L M
authors.initials: LM
authors.lastname: Podust
authors.forename: V F
authors.initials: VF
authors.lastname: Zarytova
mesh_terms: D000478:Alkylation; D001483:Base Sequence; D004247:DNA; D006863:Hydrogen-Ion Concentration; D008969:Molecular Sequence Data; D009150:Mustard Compounds; D010880:Piperidines; D011066:Poly C; D011089:Polydeoxyribonucleotides
chemical_list: D009150:Mustard Compounds; D010880:Piperidines; D011089:Polydeoxyribonucleotides; C016681:poly(dG).poly(dC); C023826:poly(dC); D011066:Poly C; C025881:4(N)-(2-chloroethyl-N-methylamino)benzylamine; C032727:piperidine; D004247:DNA