Examination of autologous and embryonic cortical brain tissue transplantation to adult brain cortex in rats.
Autologous and embryonic cortical brain tissue was transplanted to adult rats in order to reconstruct experimentally degenerated cortical brain tissue. Rats were decapitated within 6 or 12 weeks. Viability of the graft tissues was studied by light and electron microscopy. Embryonic cortical brain tissue grafts became enlarged but adult cortical brain tissue grafts were found to be unaltered. Electron-microscopically observed mitochondria and other cell organellae and the newly vascularized areas clearly showed that the graft tissues were alive.
Palaoğlu
S
S
Department of Neurosurgery, School of Medicine, University of Hacettepe, Ankara, Turkey.
Benli
K
K
Pamir
N
N
Erbengi
T
T
Erbengi
A
A
D000818:Animals; D002540:Cerebral Cortex / Q000196:embryology / Q000502:physiology* / Q000637:transplantation / Q000648:ultrastructure; D008854:Microscopy, Electron; D051381:Rats