title: A rapid method for the quantification of C, N and O in biomedical samples by proton-induced gamma-ray emission analysis applied to human placental samples.
abstract: A new fast, accurate and simple quantification method for C, N and O in biomedical samples by external-beam proton-induced gamma-ray emission analysis is presented. Concentration values for C, N and O in commercial standards of NBS bovine liver 1577a, IAEA animal muscle H-4 and IAEA horse kidney H-8 were determined using the new method. The concentrations of C, N, O, Na, Mg and P were determined from placental samples of 13 alcoholic mothers and from 16 abstinent controls. The values obtained for C, N, O, Mg and P were the first values ever obtained for human placentas.
authors.affiliation: Department of Physics, University of Helsinki, Finland.
authors.forename: R
authors.initials: R
authors.lastname: Lapatto
authors.forename: J
authors.initials: J
authors.lastname: Räisänen
mesh_terms: D000437:Alcoholism / Q000378:metabolism; D002244:Carbon / Q000032:analysis* / Q000592:standards; D005260:Female; D006801:Humans; D008274:Magnesium / Q000032:analysis; D008722:Methods; D009584:Nitrogen / Q000032:analysis* / Q000592:standards; D010100:Oxygen / Q000032:analysis* / Q000592:standards; D010758:Phosphorus / Q000032:analysis; D010920:Placenta / Q000032:analysis*; D011247:Pregnancy; D011248:Pregnancy Complications; D012964:Sodium / Q000032:analysis
chemical_list: D010758:Phosphorus; D002244:Carbon; D012964:Sodium; D008274:Magnesium; D009584:Nitrogen; D010100:Oxygen