title: Infection and diarrhea caused by Cryptosporidium sp. among Guatemalan infants.
abstract: During July 1985 to June 1986, fecal excretion of Cryptosporidium oocysts was determined prospectively in a cohort of 130 infants, aged 0 to 11 months, living in a marginal urban area of Guatemala City, Guatemala. A total of 1,280 stool specimens were examined; 158 of them were collected during episodes of diarrhea, and 1,122 were collected during symptom-free periods, every 2 to 3 weeks, from every child. Of the children, 20 (15.4%) excreted Cryptosporidium oocysts during the observation period. Of the diarrheal episodes, 13 (8.3%) were associated with Cryptosporidium sp. Of the control specimens, seven (0.6%) were positive for oocysts. Most of the infections were documented during the months of February to May, at the end of the dry season. Cryptosporidium infections are very common among Guatemalan infants and are an important cause of diarrhea and weight loss. The introduction of liquid or solid foods in the diets of the children, the presence of domestic animals (dogs, cats, or poultry), and the absence of toilet facilities in the house seem to be important risk factors for infection; also, deficient nutritional status may predispose the infected child to Cryptosporidium-associated illness.
authors.affiliation: Division of Nutrition and Health, Institute of Nutrition of Central America and Panama, Guatemala City.
authors.forename: J R
authors.initials: JR
authors.lastname: Cruz
authors.forename: F
authors.initials: F
authors.lastname: Cano
authors.forename: P
authors.initials: P
authors.lastname: Càceres
authors.forename: F
authors.initials: F
authors.lastname: Chew
authors.forename: G
authors.initials: G
authors.lastname: Pareja
mesh_terms: D000367:Age Factors; D003457:Cryptosporidiosis / Q000453:epidemiology / Q000209:etiology*; D003968:Diarrhea, Infantile / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006166:Guatemala; D006801:Humans; D007223:Infant; D007225:Infant Food; D008297:Male; D009752:Nutritional Status; D011446:Prospective Studies; D012737:Sex Factors