Vitamin E deficiency in phrynoderma cases from Sri Lanka.
Phrynoderma cases were identified in a village close to Colombo in Sri Lanka. The alpha-tocopherol level in plasma was 3.3 +/- 0.6 mumol/L among the phrynoderma patients (n = 11) and 13.0 +/- 2.3 mumol/L among the control subjects (p less than 0.002). A test on glutathione reductase activity in erythrocytes revealed a stronger riboflavin deficiency among patients than among control subjects (p less than 0.005). No significant differences were found between the groups with regard to plasma levels of retinol, retinol-binding protein, vitamin B-12, folic acid, thiamin, selenium, zinc, or essential fatty acid pattern. Primary malnutrition may partly explain the deficiency of alpha-tocopherol and riboflavin observed in phrynoderma cases.
Christiansen
E N
EN
Institute for Nutrition Research, University of Oslo, Norway.
Piyasena
C
C
Bjørneboe
G E
GE
Bibow
K
K
Nilsson
A
A
Wandel
M
M
D000328:Adult; D007644:Darier Disease / Q000097:blood / Q000209:etiology*; D004034:Diet Surveys; D005260:Female; D006801:Humans; D012256:Riboflavin / Q000097:blood; D012257:Riboflavin Deficiency / Q000097:blood / Q000150:complications; D012424:Rural Population; D012959:Socioeconomic Factors; D013188:Sri Lanka; D014810:Vitamin E / Q000097:blood; D014811:Vitamin E Deficiency / Q000097:blood / Q000150:complications*
D014810:Vitamin E; D012256:Riboflavin