Nitroso-aldicarb induces sister-chromatid exchanges in human lymphocytes in vitro.
Nitroso-aldicarb was tested for its ability to induce sister-chromatid exchanges (SCE) and cell-cycle delay in human peripheral blood lymphocytes in vitro. This derivative of aldicarb induced a dose-dependent increase in SCE values per cell. In addition, a slight decrease in the successive mitotic progression of cells in culture was observed.
González Cid
M G
MG
Instituto de Oncología Angel H. Roffo, Departamento de Investigaciones, Buenos Aires, Argentina.
Loria
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Matos
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D000448:Aldicarb / Q000494:pharmacology*; D002453:Cell Cycle / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D007306:Insecticides / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects; D009153:Mutagens; D009603:Nitroso Compounds / Q000494:pharmacology*; D012854:Sister Chromatid Exchange / Q000187:drug effects*
D007306:Insecticides; D009153:Mutagens; D009603:Nitroso Compounds; D000448:Aldicarb