Hormone receptors in breast cancer: a conservative determination of receptors' presence in tumor tissue and ipsilateral normal mammary gland.
Estrogen (ER) and progesterone (PgR) receptors were evaluated in the tumor tissue (T) and in the mammary gland far from malignancy (D) in 36 breast cancers. Results were correlated with the pathological grading of the tumor and the axillary nodal status. It is suggested that a lower cancer malignancy with negative nodes and lower values of pathological grading (G1-G2) may be associated with a high level of ER in the mammary parenchyma far from the tumor (D).
Badellino
F
F
Department of Clinical Oncology, Istituto per la Ricerca sul Cancro, Genova, Italy.
Canavese
G
G
Catturich
A
A
Battistini
G
G
Amoretti
G
G
Bertoglio
S
S
Boccardo
F
F
Paganuzzi
M
M
Tanara
G
G
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D001940:Breast / Q000032:analysis* / Q000473:pathology; D001943:Breast Neoplasms / Q000032:analysis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008408:Mastectomy; D008593:Menopause; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone