title: Treatment of respiratory tract infections with pefloxacin in critically ill patients hospitalized in a surgical intensive care unit.
abstract: Respiratory tract infections were treated with pefloxacin in fifteen patients, who were hospitalized in the intensive care unit and required artificial ventilation. The treatment was successful in ten patients. Development of resistance was observed in Staphylococcus aureus (two times) and Pseudomonas aeruginosa (four times). No adverse reactions were seen.
authors.affiliation: Department of Surgery, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: D M
authors.initials: DM
authors.lastname: Boland
authors.forename: W C
authors.initials: WC
authors.lastname: van Gestel
authors.forename: D M
authors.initials: DM
authors.lastname: MacLaren
authors.forename: D
authors.initials: D
authors.lastname: de Jong
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D003422:Critical Care; D004352:Drug Resistance, Microbial; D006801:Humans; D009643:Norfloxacin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015366:Pefloxacin; D011552:Pseudomonas Infections / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D013203:Staphylococcal Infections / Q000188:drug therapy
chemical_list: D015366:Pefloxacin; D009643:Norfloxacin