title: Experimental intraocular lens implantation in the rabbit eye and in the mouse peritoneal space. Part III: Giant cell formation on the implanted lens surface.
abstract: Among the cell components appearing on an implanted intraocular lens (IOL), the macrophage is the most active participant in the foreign-body response. The morphological stages of the macrophage in the response include not only an activated form and a flat epithelioid cell, but also a giant cell observed in the later stage of the response. The giant cells on the IOLs implanted in the rabbit eye and in the mouse peritoneal space were investigated by means of Wolter's implant cytology staining and scanning and transmission electron microscopic observation. Differences in the two biological environments as the site of IOL implantation are discussed.
authors.affiliation: Department of Ophthalmology, Wakayama Medical College, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Uenoyama
authors.forename: R
authors.initials: R
authors.lastname: Kanagawa
authors.forename: M
authors.initials: M
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Matoba
authors.forename: Y
authors.initials: Y
authors.lastname: Enomoto
authors.forename: S
authors.initials: S
authors.lastname: Ohmi
mesh_terms: D000818:Animals; D005123:Eye / Q000276:immunology / Q000648:ultrastructure; D007910:Lenses, Intraocular; D008262:Macrophage Activation; D008264:Macrophages / Q000276:immunology / Q000648:ultrastructure*; D008768:Methylmethacrylates / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D010529:Peritoneal Cavity / Q000276:immunology / Q000648:ultrastructure; D011817:Rabbits; D012828:Silicones / Q000494:pharmacology
chemical_list: D008768:Methylmethacrylates; D012828:Silicones