title: [Changes in the function and energy metabolism of the myocardium in experimental diabetes mellitus in dogs].
abstract: Coronary arteries, coronary sinus, heart cavities, and great vessels were catheterized in anesthetized dogs with alloxan diabetes. Cardiac contractility, coronary and systemic circulation, myocardial energy metabolism and acid-base balance were studied. It was shown that the alterations of the cardiac function occurred in experimental dogs with severe diabetes mellitus. They consisted of a decrease in cardiac and working outputs, ejection period, maximum velocity of the left ventricular contractions and an increase in the projection period. These dysfunctions were caused by the alterations of the myocardial energy metabolism and systemic changes in the acid-base balance.
authors.forename: A I
authors.initials: AI
authors.lastname: Khomaziuk
authors.forename: A P
authors.initials: AP
authors.lastname: Neshcheret
authors.forename: L N
authors.initials: LN
authors.lastname: Glebova
authors.forename: L P
authors.initials: LP
authors.lastname: Derevianko
authors.forename: I V
authors.initials: IV
authors.lastname: Shepelenko
mesh_terms: D000136:Acid-Base Equilibrium; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology*; D004285:Dogs; D004734:Energy Metabolism; D005260:Female; D006321:Heart / Q000503:physiopathology*; D008297:Male; D009200:Myocardial Contraction
vernacular_title: Izmeneniia funktsii i énergeticheskogo obmena miokarda pri éksperimental'nom sakharnom diabete u sobak.