title: Beta-substituted phenethylamines as high-affinity mechanism-based inhibitors of dopamine beta-hydroxylase.
authors.affiliation: Department of Medicinal Chemistry, Smith Kline & French Laboratories, Swedeland, Pennsylvania 19406.
authors.forename: L I
authors.initials: LI
authors.lastname: Kruse
authors.forename: C
authors.initials: C
authors.lastname: Kaiser
authors.forename: W E
authors.initials: WE
authors.lastname: DeWolf
authors.forename: P A
authors.initials: PA
authors.lastname: Chambers
authors.forename: P J
authors.initials: PJ
authors.lastname: Goodhart
authors.forename: M
authors.initials: M
authors.lastname: Ezekiel
authors.forename: E H
authors.initials: EH
authors.lastname: Ohlstein
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002417:Cattle; D004299:Dopamine beta-Hydroxylase / Q000037:antagonists & inhibitors*; D006973:Hypertension / Q000201:enzymology; D007700:Kinetics; D010627:Phenethylamines / Q000494:pharmacology*; D051381:Rats; D011918:Rats, Inbred SHR; D013329:Structure-Activity Relationship; D013997:Time Factors
chemical_list: D010627:Phenethylamines; D004299:Dopamine beta-Hydroxylase