Relapse of intermediate or high-grade (unfavorable) non-Hodgkin's lymphoma as a low-grade (favorable) Non-Hodgkin's lymphoma. Report of four cases.
The authors present four cases of low-grade (favorable) non-Hodgkin's lymphoma appearing after successful treatment of intermediate or high-grade (unfavorable) non-Hodgkin's lymphoma. In each case, the patient had intermediate or high-grade non-Hodgkin's lymphoma, received multiagent chemotherapy, and entered complete remission lasting one to six years. Each patient had a relapse with low-grade non-Hodgkin's lymphoma. Possible explanations and therapeutic implications are discussed.
Head
D R
DR
Department of Pathology, University of Utah Medical Center, Salt Lake City 84132.
Avakian
J
J
Kjeldsberg
C R
CR
Cerezo
L
L
D000328:Adult; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012074:Remission Induction