Pseudohyperparathyroidism secondary to gigantic mammary hypertrophy.
Pseudohyperparathyroidism encompasses both ectopic hyperparathyroidism and the more commonly encountered nonparathyroid humoral hypercalcemia of malignancy--metastatic breast cancer being the classic example. Benign breast disease is a rare cause of hypercalcemia. We recently managed a patient with gigantic mammary hypertrophy that occurred during pregnancy who concomitantly manifested marked nonparathyroid hypercalcemia. This report strongly suggests that a casual relationship exists between benign breast disease and hypercalcemia.
Van Heerden
J A
JA
Section of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, MN 55905.
Gharib
H
H
Jackson
I T
IT
D000328:Adult; D001940:Breast / Q000473:pathology*; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000097:blood / Q000209:etiology*; D006984:Hypertrophy / Q000473:pathology; D008408:Mastectomy; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000601:surgery
D010281:Parathyroid Hormone; D010758:Phosphorus; D002118:Calcium