Eosinophilia, respiratory symptoms and pulmonary infiltrates in rubber workers.
This report describes a spectrum of respiratory illnesses associated with eosinophilia which occurred in a group of workers exposed to fumes from a synthetic rubber-based curing operation. Respiratory syndromes induced by this exposure included an acute sensitizing illness with dyspnea and wheezing in some workers and pulmonary infiltrates with eosinophilia in others. Another worker developed chronic obstruction of the airways with recurrent bronchitic illnesses. Mild to marked peripheral eosinophilia, up to 3,000/cu mm, was usually present in the symptomatic workers and in 11 of 30 asymptomatic workers. These cases illustrate the diversity of respiratory illnesses which may result from a common workplace exposure and reinforce the importance of considering occupational exposures in the differential diagnosis of peripheral eosinophilia.
Bascom
R
R
Center for Occupational and Environmental Health, Johns Hopkins Medical Institutions, Wyman Park Health System, Baltimore.
Fisher
J F
JF
Thomas
R J
RJ
Yang
W N
WN
Baser
M E
ME
Baker
J H
JH
D000208:Acute Disease; D000328:Adult; D002737:Chloroprene / Q000009:adverse effects; D004802:Eosinophilia / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D011859:Radiography; D012140:Respiratory Tract Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D012408:Rubber / Q000009:adverse effects*; D013147:Spirometry
D002737:Chloroprene; D012408:Rubber