title: Crystallography and site-directed mutagenesis of yeast triosephosphate isomerase: what can we learn about catalysis from a "simple" enzyme?
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139.
authors.forename: T C
authors.initials: TC
authors.lastname: Alber
authors.forename: R C
authors.initials: RC
authors.lastname: Davenport
authors.forename: D A
authors.initials: DA
authors.lastname: Giammona
authors.forename: E
authors.initials: E
authors.lastname: Lolis
authors.forename: G A
authors.initials: GA
authors.lastname: Petsko
authors.forename: D
authors.initials: D
authors.lastname: Ringe
mesh_terms: D001665:Binding Sites; D002238:Carbohydrate Epimerases / Q000235:genetics*; D002384:Catalysis; D003461:Crystallography; D007700:Kinetics; D008958:Models, Molecular; D009154:Mutation; D011485:Protein Binding; D011487:Protein Conformation; D012441:Saccharomyces cerevisiae / Q000201:enzymology* / Q000235:genetics; D014305:Triose-Phosphate Isomerase / Q000235:genetics* / Q000378:metabolism
chemical_list: D002238:Carbohydrate Epimerases; D014305:Triose-Phosphate Isomerase