Postoperative radiation and implant capsule contraction.
Occasionally radiation is required as adjunctive therapy following mastectomy for breast cancer. The effects of radiation on a developing implant capsule are unknown, but they are very important in relation to the increased use of immediate reconstruction. Experiments were performed on rabbits to study the effects of postoperative radiation therapy on capsule contraction and thickness. The results of these experiments suggest that radiation has no effect on implant capsules.
Caffee
H H
HH
Division of Plastic and Reconstructive Surgery, University of Florida College of Medicine, Gainesville 32610.
Mendenhall
N P
NP
Mendenhall
W M
WM
Bova
F J
FJ
D000016:Abnormalities, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D000818:Animals; D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery; D003286:Contracture / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D019736:Prostheses and Implants; D011817:Rabbits; D012826:Silicone Elastomers; D014945:Wound Healing / Q000528:radiation effects
D012826:Silicone Elastomers