title: Disopyramide-induced hypoglycaemia and increased serum insulin.
abstract: A patient treated with disopyramide presented with hypoglycaemia, a raised serum insulin level and died of pneumonia. From these findings and a review of 10 case reports, we propose that disopyramide causes hypoglycaemia by stimulation of insulin release as described for the antimalarial drugs quinine and quinidine.
authors.affiliation: Department of Endocrinology, Auckland Hospital.
authors.forename: M S
authors.initials: MS
authors.lastname: Croxson
authors.forename: D W
authors.initials: DW
authors.lastname: Shaw
authors.forename: P G
authors.initials: PG
authors.lastname: Henley
authors.forename: H D
authors.initials: HD
authors.lastname: Gabriel
mesh_terms: D000368:Aged; D004206:Disopyramide / Q000009:adverse effects*; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000139:chemically induced*; D007328:Insulin / Q000097:blood*; D008297:Male; D013268:Stimulation, Chemical
chemical_list: D007328:Insulin; D004206:Disopyramide