title: Species specificity in the responsiveness of chick embryo neural tube explants to target-conditioned medium.
abstract: Explants from the metencephalic region of 40-h chick embryo neural tubes containing the trigeminal (V) motor nucleus were cultured in appropriate target muscle-conditioned media (MCM) derived from chick, quail and rat embryos. Enhanced neuritic outgrowth was found only in the presence of chick MCM, indicating that this early, initial responsiveness to target-released materials within this system is species-specific.
authors.affiliation: Department of Neuroscience, University of Florida College of Medicine, Gainesville 32610.
authors.forename: M B
authors.initials: MB
authors.lastname: Heaton
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D003470:Culture Media / Q000494:pharmacology*; D009132:Muscles / Q000378:metabolism*; D009414:Nerve Growth Factors / Q000378:metabolism / Q000494:pharmacology*; D009432:Neural Crest / Q000166:cytology / Q000187:drug effects; D011784:Quail; D051381:Rats; D013045:Species Specificity; D014279:Trigeminal Nucleus, Spinal / Q000187:drug effects / Q000196:embryology*
chemical_list: D003470:Culture Media; D009414:Nerve Growth Factors