title: Results of clinical trials with ciprofloxacin in Italy.
abstract: The Authors report about the results of 23 clinical trials carried out in Italy with oral formulations of BAY o 9867 (ciprofloxacin) in the treatment of infections in various sites of the body. Altogether 644 patients were evaluated for therapeutic efficacy; positive clinical results were obtained in 95 to 100% of the treated patients, according to the site of the infection. The bacteriological examinations performed on 575 cases show eradication in 89.22%, eradication with relapse or reinfection in 2.26%, and persistence in 6.09%. Adverse reactions were observed in 38 out of 646 patients (5.89%); none of them, however, were severe or irreversible.
authors.affiliation: Medical Department, Bayer Italia, Milano, Italy.
authors.forename: W
authors.initials: W
authors.lastname: Bianchi
authors.forename: A
authors.initials: A
authors.lastname: Imbasciati
authors.forename: L
authors.initials: L
authors.lastname: Mariani
authors.forename: H
authors.initials: H
authors.lastname: Ohnmeiss
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002648:Child; D002939:Ciprofloxacin / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male
chemical_list: D002939:Ciprofloxacin