Measurement of global and regional left ventricular performance with isotope technique in coronary heart disease.
In order to evaluate the left ventricular function in coronary artery disease, radionuclide measurements of global and regional ejection fraction (EF), regional wall motion and phase analyses of the left ventricular contraction were performed by equilibrium technique. One group of patients with angina pectoris and one group with myocardial infarction were compared with a control group. All the above-mentioned parameters significantly separated the infarction group from the reference group both at rest and during work, while the group of patients with angina pectoris showed disturbances mainly during work, such as impaired ability to increase global and regional ejection fraction and regional wall motion. Adding regional analysis and phase analysis to the global EF determination increases the possibility of studying the left ventricular function. However, this addition has a limited value in detecting impaired left ventricular function compared to the determination of just global EF in patients with angina pectoris and in patients with myocardial infarction.
Boström
P A
PA
Department of Clinical Physiology, Lund University, Malmö General Hospital, Sweden.
Svensson
M
M
Lilja
B
B
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology*; D011875:Radionuclide Angiography; D013318:Stroke Volume