[Antilymphocytic humoral autoimmune response of mice with developing Rauscher leukemia directed against group-specific retrovirus antigens].
The methods of indirect membrane immunofluorescence, immunoenzyme analysis, complement-dependent cytotoxicity and sorption tests were used to demonstrate two types of humoral antilymphocytic autoimmune reactions at the early stage of the Rauscher leukemia in mice of BALB/c, BDF1 and C57B1/6 strains. The first one is directed against group-specific oncoviral antigens (p30, p15) expressed on the lymphocyte membrane of both intact mice and of those with leukemia, the second one is virus-independent and possesses strain specificity.
Ter-Grigorov
V S
VS
Graf
I A
IA
Pivnik
A V
AV
Etkin
A F
AF
Moskovkina
O Ia
OIa
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D000954:Antigens, Surface / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology*; D001323:Autoantibodies / Q000032:analysis*; D001667:Binding, Competitive; D005455:Fluorescent Antibody Technique; D007942:Leukemia, Experimental / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D011925:Rauscher Virus / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000914:Antibodies, Viral; D000954:Antigens, Surface; D000956:Antigens, Viral; D001323:Autoantibodies
Antilimfotsitarnye gumoral'nye autoimmunnye reaktsii mysheĭ s razvivaiushchimsia leĭkozom Raushera, napravlennye protiv gruppospetsificheskikh antigenov retrovirusov.