Acyclovir in human breast milk.
Acyclovir concentration was measured by radioimmunoassay in the serum and milk of a lactating woman who was treated with oral acyclovir for herpes zoster. Daily serum and milk samples showing milk concentrations that averaged being 3.24-fold higher than serum levels suggest a low infant dose. The elimination phase demonstrated a half-life of 2.8 hours in milk.
Meyer
L J
LJ
Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City.
de Miranda
P
P
Sheth
N
N
Spruance
S
S
D000212:Acyclovir / Q000032:analysis / Q000097:blood / Q000493:pharmacokinetics*; D000328:Adult; D005260:Female; D006207:Half-Life; D006801:Humans; D008895:Milk, Human / Q000032:analysis*; D011863:Radioimmunoassay
D000212:Acyclovir