title: Enzyme immunoassay for detection of antigen in acute Plasmodium falciparum malaria.
abstract: A monoclonal antibody specific for an epitope of a 50 kDa Plasmodium falciparum antigen was used in an enzyme immunoassay for detection of the corresponding exo-antigen in culture supernatant and in the sera of 31 patients suffering from acute malaria. The assay was specific for Plasmodium falciparum and did not appear to be strain restricted. A parasitaemia level below 0.001% could be detected.
authors.affiliation: Unité 42 INSERM, Villeneuve d'Ascq, France.
authors.forename: B
authors.initials: B
authors.lastname: Fortier
authors.forename: P
authors.initials: P
authors.lastname: Delplace
authors.forename: J F
authors.initials: JF
authors.lastname: Dubremetz
authors.forename: F
authors.initials: F
authors.lastname: Ajana
authors.forename: A
authors.initials: A
authors.lastname: Vernes
mesh_terms: D000208:Acute Disease; D000818:Animals; D000911:Antibodies, Monoclonal; D000953:Antigens, Protozoan / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D008288:Malaria / Q000175:diagnosis*; D010963:Plasmodium falciparum / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000953:Antigens, Protozoan