title: Severe myalgia in familial Mediterranean fever: clinical and ultrastructural aspects.
abstract: Severe myalgia is an uncommon feature of familial Mediterranean fever (FMF). A patient is presented in whom acute myalgia and high fever were the sole clinical findings during an FMF attack. The ultrastructural picture of the muscle tissue during the acute stage was characterised by a large deposition of collagen fibrils. The myalgia subsided during colchicine treatment. The clinical and ultrastructural features of myalgia in FMF are discussed in the light of the relevant literature.
authors.affiliation: Department of Rheumatology, Rambam Medical Center, Haifa, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Schapira
authors.forename: R
authors.initials: R
authors.lastname: Ludatscher
authors.forename: M
authors.initials: M
authors.lastname: Nahir
authors.forename: M
authors.initials: M
authors.lastname: Lorber
authors.forename: Y
authors.initials: Y
authors.lastname: Scharf
mesh_terms: D000208:Acute Disease; D000328:Adult; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007866:Leg; D009132:Muscles / Q000648:ultrastructure*; D009135:Muscular Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D010146:Pain / Q000209:etiology* / Q000473:pathology