A new prealbumin variant in familial amyloid cardiomyopathy of Danish origin.
A C-terminal fragment of a prealbumin variant was isolated from amyloid material obtained from the myocardium of a patient (Han) with familial amyloid cardiomyopathy of Danish origin. The prealbumin variant fragment was shown to have a methionine for leucine substitution in position 111.
Nordlie
M
M
Institute of Biochemistry, University of Oslo, Norway.
Sletten
K
K
Husby
G
G
Ranløv
P J
PJ
D000595:Amino Acid Sequence; D000682:Amyloid / Q000235:genetics / Q000302:isolation & purification*; D000686:Amyloidosis / Q000235:genetics / Q000378:metabolism*; D009202:Cardiomyopathies / Q000235:genetics / Q000378:metabolism*; D003718:Denmark / Q000208:ethnology; D006801:Humans; D008969:Molecular Sequence Data; D011228:Prealbumin / Q000235:genetics / Q000302:isolation & purification*
D000682:Amyloid; D011228:Prealbumin