Immunoglobulin allotypes in caucasian and Chinese myasthenia gravis: differences from Japanese patients.
The G2m(n) allotype was significantly increased in Chinese female and high autoantibody cases, and in caucasians with pure ocular myasthenia, or undetectable autoantibody. In contrast to the strong Glm(x) association reported in Japanese, no overall Gm haplotype, or Am or Km allotype association was found in 90 (Taiwan) Chinese and 181 caucasian myasthenia gravis patients.
Chiu
H C
HC
Department of Neurology, National Taiwan University Hospital, Taipei.
de Lange
G G
GG
Willcox
N
N
Vincent
A
A
Newsom-Davis
J
J
Hsieh
K H
KH
Hung
T P
TP
D000328:Adult; D002681:China; D005006:Ethnicity; D005260:Female; D005787:Gene Frequency; D006239:Haplotypes; D006801:Humans; D007129:Immunoglobulin Gm Allotypes / Q000235:genetics*; D007564:Japan; D008131:London; D008297:Male; D009157:Myasthenia Gravis / Q000235:genetics*
D007129:Immunoglobulin Gm Allotypes