title: Neurologic disease in biopsy-proven giant cell (temporal) arteritis.
abstract: Neurologic findings were studied in 166 consecutive patients with biopsy-proven giant cell (temporal) arteritis. Neurologic problems occurred in 51 patients (31%): neuropathies (23), TIA/strokes (12), neuro-otologic syndromes (11), tremor (6), neuropsychiatric syndromes (5), tongue numbness (3), and myelopathy (1). Neuro-ophthalmologic problems occurred in 35 patients (21%): amaurosis fugax (AF) (17), permanent vision loss (PVL) (14), scintillating scotoma (8), and diplopia (3). Abnormalities in large arteries in 52 patients (31%) included bruits and diminished pulses. The carotid artery was involved in 31 patients (bilateral in 58%). Overall, 35% of patients with carotid disease had TIA/stroke, AF, or PVL.
authors.affiliation: Department of Neurology, Mayo Clinic, Rochester, MN 55905.
authors.forename: R J
authors.initials: RJ
authors.lastname: Caselli
authors.forename: G G
authors.initials: GG
authors.lastname: Hunder
authors.forename: J P
authors.initials: JP
authors.lastname: Whisnant
mesh_terms: D000368:Aged; D001706:Biopsy; D002561:Cerebrovascular Disorders / Q000150:complications; D003866:Depressive Disorder / Q000150:complications; D004427:Ear Diseases / Q000150:complications; D005128:Eye Diseases / Q000150:complications; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000150:complications; D009422:Nervous System Diseases / Q000150:complications*; D012677:Sensation; D014059:Tongue / Q000294:innervation; D014202:Tremor / Q000150:complications