title: Excessive blood loss and its relationship to clotting system changes during and after major surgery.
abstract: The massively hemorrhaging patient still remains one of the major problems that can be faced by the general surgeon. This article attempts to summarize the biophysiology of this process in an intuitively understandable manner that has direct clinical applications.
authors.affiliation: University of California, Irvine.
authors.forename: R S
authors.initials: RS
authors.lastname: Newman
mesh_terms: D001779:Blood Coagulation Factors / Q000378:metabolism; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology*; D006470:Hemorrhage / Q000097:blood / Q000209:etiology*; D006487:Hemostasis; D006801:Humans; D010974:Platelet Aggregation; D013514:Surgical Procedures, Operative
chemical_list: D001779:Blood Coagulation Factors