[Pancreatic stone protein, a new marker for chronic pancreatitis].
A CaCO3 precipitation and crystal growth inhibitor has recently been isolated from pancreatic calculi and from pancreatic juice. It is a glycoprotein with a molecular weight of 14,000, whose probable physiological role is the stabilization of exocrine pancreatic secretion which is normally supersaturated with CaCO3. It is hoped to determine a simple, but sensitive assay of this new protein on pancreatic juice and on serum, a decrease in which could be a marker for chronic pancreatitis.
Montalto
G
G
Università degli Studi di Palermo Cattedra di Patologia Medica.
Carroccio
A
A
Notarbartolo
A
A
D000437:Alcoholism / Q000150:complications; D002135:Calcium-Binding Proteins / Q000032:analysis*; D002137:Calculi / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D002908:Chronic Disease; D006801:Humans; D051847:Lithostathine; D009419:Nerve Tissue Proteins; D010195:Pancreatitis / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism
D002135:Calcium-Binding Proteins; D051847:Lithostathine; D009419:Nerve Tissue Proteins; C497617:REG1A protein, human
La "pancreatic stone protein", un nuovo marker di pancreatite cronica.