Gas-chromatographic measurement of carboxyhemoglobin in blood from mothers and newborns.
HbCO in blood sampled from 20 mothers and newborns immediately after birth was measured with a new, simple gas-chromatographic method for CO. The mean ratio of HbCO to total hemoglobin for 13 non-smoking mothers did not differ significantly from that for their infants (mean 0.38%, SD 0.26% vs 0.38%, SD 0.13%), but the HbCO ratio varied more in the mothers than in the infants (P less than 0.05). The infants of seven cigarette-smoking mothers, tobacco-abstinent for 7 h during labor, had higher HbCO ratios than their mothers (mean 1.88% vs 1.28%, P less than 0.05). The results are in harmony with the concept of equal affinities of fetal and adult hemoglobin for CO and a long time for passage of CO across the placenta.
Fogh-Andersen
N
N
Department of Clinical Chemistry, Herlev Hospital, Denmark.
Eriksen
P S
PS
Grinsted
J
J
Siggaard-Andersen
O
O
D002263:Carboxyhemoglobin / Q000097:blood*; D002849:Chromatography, Gas; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D012907:Smoking / Q000097:blood
D002263:Carboxyhemoglobin