Polymorphic light eruption sine eruption.
We describe seven patients, four female and three male, who developed intense pruritus on sun-exposed skin without visible change. The clinical features resembled those of polymorphic light eruption (PLE) without rash. Four patients also occasionally developed typical PLE upon sun exposure, but sun-induced pruritus alone occurred most frequently. No patient was taking any drug therapy. One patient developed similar pruritus following solar simulated irradiation, and one following PUVA therapy. All other laboratory investigations were negative. Treatment with low dose UVB phototherapy or PUVA therapy was effective. The condition, which we have called polymorphic light eruption sine eruptione (PLESE), appears to be a variant of PLE not previously reported.
Dover
J S
JS
Department of Photobiology, St Thomas's Hospital, London, U.K.
Hawk
J L
JL
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D011701:PUVA Therapy / Q000009:adverse effects; D010787:Photosensitivity Disorders / Q000150:complications*; D011537:Pruritus / Q000209:etiology*