Dedifferentiated chondrosarcoma.
The cases of forty-six patients who had dedifferentiated chondrosarcoma were reviewed. Two groups were identified: one in which a low-grade malignant chondrosarcoma was the precursor lesion and one in which a moderate to high-grade malignant chondrosarcoma was the precursor lesion. The radiographic features of these lesions ranged from that of a cartilaginous lesion that appeared to be benign to that of a destructive osteolytic tumor in which the cartilaginous component was overshadowed by the dedifferentiated component. Only three of the forty-six patients survived for more than two years. Resection alone, even when it was wide or radical, was not successful in controlling this lethal sarcoma.
Capanna
R
R
1st Orthopaedic Clinic, Istituto Ortopedico Rizzoli, Bologna, Italy.
Bertoni
F
F
Bettelli
G
G
Picci
P
P
Bacchini
P
P
Present
D
D
Giunti
A
A
Campanacci
M
M
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000145:classification / Q000000981:diagnostic imaging* / Q000473:pathology; D002813:Chondrosarcoma / Q000145:classification / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed