title: [Epithelial neoplasms of Vater's ampulla: anatomico-clinical and immunohistochemical study].
abstract: 3 adenomas and 5 carcinomas of the ampulla of Vater are studied to evaluate their histogenesis and diagnostic significance of the antigen defined by the monoclonal antibody CA 19/9. In the adenomas, some dysplastic glands show a faint positivity for CA 19/9 antigen, whereas in the ampullomas this antigen is present in adenomatous residue and in well differentiated adenocarcinomatous areas. The present observations indicate that the endoscopical and macro-microscopical examinations are fundamental to evaluate the location of the ampullary neoplasia. Moreover, the immunohistochemical finding of the CA 19/9 antigen in adenomas and carcinomas suggests their histogenetic relationship, but it is not useful in their differential diagnosis.
authors.affiliation: Università degli Studi di Messina Dipartimento di Patologia Umana.
authors.forename: R
authors.initials: R
authors.lastname: Caruso
authors.forename: C
authors.initials: C
authors.lastname: Campolo
authors.forename: G
authors.initials: G
authors.lastname: Speciale
authors.forename: G
authors.initials: G
authors.lastname: Casablanca
authors.forename: S
authors.initials: S
authors.lastname: Catanese
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000236:Adenoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D014670:Ampulla of Vater / Q000473:pathology* / Q000601:surgery; D000911:Antibodies, Monoclonal; D002277:Carcinoma / Q000473:pathology* / Q000601:surgery; D003138:Common Bile Duct Neoplasms / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D004724:Endoscopy; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D011379:Prognosis
chemical_list: D000911:Antibodies, Monoclonal
vernacular_title: Neoplasie epiteliali dell'ampolla di Vater: studio anatomo-clinico ed immunoistochimico.