Multiple karyotypic rearrangements, including t(X;18)(p11;q11), in a fibrosarcoma.
The tumor stem line of a soft tissue fibrosarcoma, histologic malignancy grade III, had 43 chromosomes with several clonal chromosome aberrations, including the three balanced translocations t(X;18)(p11;q11), t(2;15)(p23;q26), and t(7;22)(q11;q13), two partly identifiable marker chromosomes, der(3)dic(3;?)(p11;?) and der(5), one small marker of unknown origin, and loss of one chromosome #11, #18, #19, and #21.
Mandahl
N
N
Department of Clinical Genetics, University Hospital, Lund, Sweden.
Heim
S
S
Arheden
K
K
Rydholm
A
A
Willén
H
H
Mitelman
F
F
D000328:Adult; D002887:Chromosomes, Human, Pair 18; D005354:Fibrosarcoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008297:Male; D014178:Translocation, Genetic; D014960:X Chromosome