title: [Renal cell carcinoma with a spindle-cell element--sarcomatous or sarcomatoid?].
abstract: In this study the light microscopic and electron microscopic findings in two renal cell carcinomas with spindle-cell elements are described. The ultrastructural features of the spindle-cell element of sarcomatoid renal cell carcinoma have previously been documented, namely pentalaminar desmosomes, basal lamina formation and intracytoplasmic lumina with microvilli. The electron microscopic findings in the 2 cases described here showed mesenchymal rather than epithelial differentiation. It would appear that some renal cell carcinomas with a spindle-cell element are true carcinosarcomas, rather than sarcomatoid renal cell carcinoma.
authors.affiliation: Department Anatomiese Patologie, Universiteit van die Oranje-Vrystaat, Bloemfontein.
authors.forename: A M
authors.initials: AM
authors.lastname: Rudman
authors.forename: B
authors.initials: B
authors.lastname: de Bruin
authors.forename: L J
authors.initials: LJ
authors.lastname: Duyvené de Wit
authors.forename: G M
authors.initials: GM
authors.lastname: Cooper
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000648:ultrastructure*; D002292:Carcinoma, Renal Cell / Q000648:ultrastructure*; D002296:Carcinosarcoma / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000648:ultrastructure*; D008297:Male
vernacular_title: Renaalselkarsinoom met 'n spoelvormige selelement--sarkomateus of sarkomatoïed?