Localization of the spherocytosis gene to chromosome segment 8p11.22----8p21.
A case of hereditary spherocytosis (HS) is reported. Cytogenetic study revealed a de novo minute deletion of chromosome 8. The critical portion which affected the expression of the HS phenotype appeared to be localized to 8p11.22----8p21.1.
Kitatani
M
M
Department of Clinical Genetics, Kanazawa Medical University, Ishikawa, Japan.
Chiyo
H
H
Ozaki
M
M
Shike
S
S
Miwa
S
S
D002871:Chromosome Banding; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D013103:Spherocytosis, Hereditary / Q000235:genetics*