Corynebacterium Group JK pathogen in cerebrospinal fluid shunt infection. Report of two cases.
The clinical and laboratory findings in two cases of aerobic Corynebacterium Group JK infection of cerebrospinal fluid (CSF) shunts are described. These organisms have occasionally been reported as a cause of serious infections in man but have not been reported as a cause of shunt infection. In both cases, CSF pleocytosis was limited to 20 or 60 cells with variable protein and sugar values. Fever was a constant finding, frequently accompanied by signs of central nervous system dysfunction. Corynebacterium Group JK organisms are common contaminants of the normal skin flora. When isolated from the blood and/or the CSF of a patient with a CSF shunt who has symptoms and signs compatible with infection, the organism should not be dismissed as a contaminant. A significant feature of this group is its resistance to almost all presently available antibiotics including penicillin, the cephalosporins, and the aminoglycosides. These organisms are, however, sensitive to vancomycin.
Keren
G
G
Pediatric Infectious Diseases Unit, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Geva
T
T
Bogokovsky
B
B
Rubinstein
E
E
D002555:Cerebrospinal Fluid / Q000166:cytology; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects*; D003352:Corynebacterium / Q000302:isolation & purification; D003354:Corynebacterium Infections / Q000150:complications / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D007223:Infant; D008297:Male; D010403:Penicillin Resistance; D014640:Vancomycin / Q000627:therapeutic use
D014640:Vancomycin