Leukocytosis due to adrenal metastases from malignant melanoma: reversal after bilateral adrenalectomy with long-term survival.
Leukocytosis has been noted in association with many non-hematologic malignancies in the absence of concurrent infection or metastatic involvement of bone marrow. We report a case of sustained, neutrophilic leukocytosis in a patient with disseminated malignant melanoma which reversed after bilateral adrenalectomy for adrenal metastases.
Carey
R W
RW
Medical Oncology, Massachusetts General Hospital, Boston.
Kunz
V S
VS
D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000503:physiopathology / Q000556:secondary / Q000628:therapy; D000315:Adrenalectomy; D000328:Adult; D003131:Combined Modality Therapy; D005438:Fludrocortisone / Q000627:therapeutic use; D006801:Humans; D007964:Leukocytosis / Q000209:etiology*; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000503:physiopathology / Q000556:secondary / Q000628:therapy; D011241:Prednisone / Q000627:therapeutic use
D005438:Fludrocortisone; D011241:Prednisone