Isoelectric focusing of superoxide dismutase: report of the unique SOD A*2 allele in a US white population.
An isoelectric focusing procedure in an ultranarrow pH range (5.0-5.5) polyacrylamide gel is described for the determination of superoxide dismutase (SOD) phenotypes. The occurrence of the rare SOD A*2 allele in the Caucasian population of Utah is also reported at a polymorphic frequency (0.011). The presence of the SOD A 2 unique allele in the Mormons of Utah is compatible with their historical affinity with Scandinavians.
DeCroo
S
S
Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pa.
Kamboh
M I
MI
Leppert
M
M
Ferrell
R E
RE
D000483:Alleles; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D007525:Isoelectric Focusing / Q000379:methods; D007526:Isoelectric Point; D010375:Pedigree; D011110:Polymorphism, Genetic; D012537:Scandinavian and Nordic Countries / Q000208:ethnology; D013482:Superoxide Dismutase / Q000235:genetics*
D013482:Superoxide Dismutase