title: Cardiopulmonary function in long-term survivors of childhood Hodgkin's lymphoma: a pilot study.
abstract: Twelve patients who had received mantle radiotherapy for Hodgkin's lymphoma during childhood underwent cardiopulmonary testing 7 years or more after the initial diagnosis and treatment. All but one patient had been asymptomatic. Results of echocardiography, pulmonary function tests, or exercise studies were abnormal in 9 of the 12 patients. Long-term follow-up of cardiopulmonary function will be important to determine the ultimate significance of these abnormalities. These potential complications must be considered in planning prospective therapeutic studies in children with Hodgkin's disease.
authors.affiliation: Section Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN 55905.
authors.forename: R P
authors.initials: RP
authors.lastname: Kadota
authors.forename: E O
authors.initials: EO
authors.lastname: Burgert
authors.forename: D J
authors.initials: DJ
authors.lastname: Driscoll
authors.forename: R G
authors.initials: RG
authors.lastname: Evans
authors.forename: G S
authors.initials: GS
authors.lastname: Gilchrist
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006334:Heart Function Tests; D006689:Hodgkin Disease / Q000188:drug therapy / Q000503:physiopathology* / Q000532:radiotherapy; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D013902:Radiography, Thoracic; D012129:Respiratory Function Tests