[Characteristics of the secretory activity of the respiratory cells of mouse lungs after partial chemical sympathectomy].
Partial "sympathectomy" in the neonatal BALB mice was achieved by the treatment with guanethidine. The number of neurons in the stellate ganglion decreased to 20% of the control values and remained constant throughout the subsequent period of 1 month. Partial "chemical sympathectomy" did not affect the postnatal growth and development of the lungs. Partial "chemical sympathectomy" significantly increased the number of secreting cells in bronchiolar and alveolar regions. Secretory activity of the alveolocyte population, type two, synthetizing and secreting surfactant also increased. It has been concluded that the partial "chemical sympathectomy" stimulated the alveolar surfactant secretion.
Romanova
L K
LK
Serebriakov
I S
IS
Lebedev
D B
DB
Iarygin
V N
VN
D000818:Animals; D000831:Animals, Newborn; D001980:Bronchi / Q000294:innervation / Q000378:metabolism / Q000648:ultrastructure; D004848:Epithelium / Q000378:metabolism / Q000648:ultrastructure; D006145:Guanethidine; D008168:Lung / Q000294:innervation / Q000378:metabolism* / Q000648:ultrastructure; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D011650:Pulmonary Alveoli / Q000294:innervation / Q000378:metabolism / Q000648:ultrastructure; D011663:Pulmonary Surfactants / Q000378:metabolism; D013563:Sympathectomy, Chemical
D011663:Pulmonary Surfactants; D006145:Guanethidine
Osobennosti sekretornoĭ aktivnosti kletok respiratornogo otdela legkikh mysheĭ posle chastichnoĭ "khimicheskoĭ simpatéktomii".