title: Clinical efficacy of intravenous morphine administration in hepatobiliary imaging for acute cholecystitis.
abstract: The most urgent diagnosis addressed by cholescintigraphy is acute cholecystitis. By administering low-dose intravenous morphine sulfate to patients undergoing cholescintigraphy (who demonstrate visualization of both the common bile duct and intestine and nonvisualization of the gallbladder), the time required to complete the study has been reduced to a maximum of 90 minutes. One hundred twenty-eight patients underwent cholescintigraphy for clinically suspected acute cholecystitis. Forty patients received intravenous morphine sulfate during the procedure. In patients who received morphine sulfate during the examination, the sensitivity of cholescintigraphy for the diagnosis of acute cholecystitis was 100%; the specificity was 85%.
authors.affiliation: Department of Radiology, University of California Medical Center, San Diego 92103-9981.
authors.forename: T E
authors.initials: TE
authors.lastname: Vasquez
authors.forename: G
authors.initials: G
authors.lastname: Greenspan
authors.forename: D G
authors.initials: DG
authors.lastname: Evans
authors.forename: S E
authors.initials: SE
authors.lastname: Halpern
authors.forename: W L
authors.initials: WL
authors.lastname: Ashburn
mesh_terms: D000208:Acute Disease; D002764:Cholecystitis / Q000000981:diagnostic imaging*; D006801:Humans; D007098:Imino Acids; D007275:Injections, Intravenous; D009020:Morphine / Q000008:administration & dosage; D009942:Organometallic Compounds; D011877:Radionuclide Imaging; D019785:Technetium Tc 99m Disofenin; D013997:Time Factors
chemical_list: D007098:Imino Acids; D009942:Organometallic Compounds; D009020:Morphine; D019785:Technetium Tc 99m Disofenin