title: Tumor markers carbohydrate antigens CA 19-9 and CA-50 and carcinoembryonic antigen in pancreatic cancer and benign diseases of the pancreatobiliary tract.
abstract: Sera from patients with diseases in the pancreas, gallbladder, and bile duct were analyzed for the tumor markers CA 19-9, CA-50, and carcinoembryonic antigen. In particular CA 19-9 and CA-50 appear to be valuable in differentiating malignant from benign disease in these organs. Our sample of 72 patients with pancreatic cancer also indicates that CA 19-9 and CA-50 complement each other in 21% of the cases. They are also shown to be reliable for monitoring disease: following radical surgery for pancreatic cancer low levels of CA 19-9 and CA-50 were noted, while progressive rises of these tumor markers were related to disease progression.
authors.affiliation: Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
authors.forename: U
authors.initials: U
authors.lastname: Harmenberg
authors.forename: B
authors.initials: B
authors.lastname: Wahren
authors.forename: K L
authors.initials: KL
authors.lastname: Wiechel
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis*; D001649:Bile Duct Diseases / Q000276:immunology*; D001650:Bile Duct Neoplasms / Q000276:immunology; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002761:Cholangitis / Q000276:immunology; D005705:Gallbladder Diseases / Q000276:immunology; D006801:Humans; D008103:Liver Cirrhosis / Q000276:immunology; D010182:Pancreatic Diseases / Q000276:immunology; D010190:Pancreatic Neoplasms / Q000276:immunology*; D010195:Pancreatitis / Q000276:immunology
chemical_list: D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen