title: The present state of Cowdria ruminantium cultivation in cell lines.
abstract: Attempts were made to grow 4 isolates of Cowdria ruminantium in cell lines. Three of these isolates, viz. Ball 3, Welgevonden and Kwanyanga, could be cultivated in a calf endothelial cell line, but experiments with the Kümm isolate have so far failed. The successful in vitro cultivation of 2 isolates (Welgevonden and Kwanyanga), which are also pathogenic for mice, has great potential for future studies and these aspects are discussed in this review.
authors.affiliation: Veterinary Research Institute, Onderstepoort.
authors.forename: J D
authors.initials: JD
authors.lastname: Bezuidenhout
mesh_terms: D000818:Animals; D001431:Bacteriological Techniques; D002417:Cattle; D002460:Cell Line; D051379:Mice; D012287:Rickettsiaceae / Q000254:growth & development*