title: Platelet aggregation and platelet-inhibiting drugs.
abstract: Platelet function may cause a progression of central gray matter damage after cerebrospinal hemorrhage or trauma because of the thrombotic occlusion of injured vessels or a vasospasm induced by extravasated blood. It has therefore been suggested that antiplatelet drugs could limit the extent of the neurological lesions produced by a spinal trauma. In view of this possibility, the hemostatic functions of platelets and the mechanism of action of antiplatelet drugs are briefly reviewed.
authors.affiliation: Istituto di Semeiotica Medica, University of Perugia, Italy.
authors.forename: G G
authors.initials: GG
authors.lastname: Nenci
mesh_terms: D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D013119:Spinal Cord Injuries / Q000097:blood*
chemical_list: D010975:Platelet Aggregation Inhibitors