[Experimental studies on the factors of osteogenesis by transplantation of patellar cartilage framework in rats].
The cartilage framework of the patella in rats is capable of inducing ossification after homotransplantation in many various sites: muscle, thyroid, testicle, ovary, kidney, anterior chamber of the eye, etc. The frequency of ossification does not depend on the technical conditions of the transplant, but on the age of the donors and receivers; it approximates 84 p. cent when the two rats are three weeks old. It is close to 100 p. cent in case of autotransplant. It is non-existent in case of heterotransplantation. A cartilage that is killed by alcohol or cold, has no longer osteogenetic abilities, even if it is placed in contact with live cartilage. The transplant of patellar cartilaginous framework represents a model which may be used to study the factors responsible for physiological ossification as well as the effect of various experimental conditions on osteogenesis.
Asch
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Service de Rhumatologie, CHU de Strasbourg, Hôpital de Hautepierre.
Asch
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D000818:Animals; D002358:Cartilage, Articular / Q000473:pathology / Q000637:transplantation*; D006168:Guinea Pigs; D010012:Osteogenesis; D010329:Patella; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
Recherches expérimentales sur les facteurs de l'ostéogenèse par transplantation d'ébauches cartilagineuses de rotule chez le rat.