title: Update on counseling the family with a first-degree relative with a congenital heart defect.
abstract: Updated recurrence risks figures are presented for genetic counseling of families with a congenital heart defect (CHD) in a first-degree relative. Substantial changes are recommended for counseling the family in which a parent has CHD. The risk is much greater if it is the mother rather than the father who has the heart defect. The updated figures for recurrence risks in sibs have been revised, but are not greatly changed. Our central tenet in counseling is to base risk projections on the genetic and teratogenic history in the individual family and pregnancy.
authors.affiliation: Department of Genetics and Preventive Medicine, University of Colorado School of Medicine, Denver.
authors.forename: J J
authors.initials: JJ
authors.lastname: Nora
authors.forename: A H
authors.initials: AH
authors.lastname: Nora
mesh_terms: D004812:Epidemiologic Methods; D005260:Female; D005817:Genetic Counseling; D006330:Heart Defects, Congenital / Q000453:epidemiology / Q000235:genetics*; D006801:Humans; D008297:Male; D011247:Pregnancy; D012307:Risk Factors