Noninvasive measurement of molar concentrations of 31P metabolites in vivo, using surface coil NMR spectroscopy.
The measurement of absolute concentration of 31P metabolites is described, using water 1H as an internal concentration standard. An analysis of the effect of variations in coil Q on flip angle and sensitivity is presented and verified experimentally. Concentrations of nucleoside triphosphate in rat brain and muscle have been measured.
Tofts
P S
PS
Institute of Neurology, London, United Kingdom.
Wray
S
S
D000818:Animals; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D010758:Phosphorus / Q000032:analysis / Q000378:metabolism*; D051381:Rats; D014316:Tritium
D014316:Tritium; D010758:Phosphorus