title: Extensive aganglionosis: further experience with the colonic patch graft procedure and long-term results.
abstract: During the period from 1979 to 1986, seven patients have been treated for extensive aganglionosis involving the colon and distal ileum (5 to 40 cm) employing the colonic patch graft (CPG) procedure. This consists of (1) ileostomy; (2) creation of a longitudinal side-to-side ileocolostomy between normal ileum and aganglionic ascending colon, forming a CPG; and (3) the definitive pull-through procedure. In all patients, the initial course after ileostomy was complicated by severe diarrhea, which was significantly improved by creation of the CPG. At the definitive operation several months later, the mesocolon attached to the CPG was severed to mobilize the ileocolostomy segment to the distal pelvis. Four patients in this series have been followed for 5 to 8 years. No patient has developed enterocolitis requiring hospitalization. Body weight became normal for age in all patients within 4 years of the definitive operation.
authors.affiliation: Department of Surgery, Kobe Children's Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kimura
authors.forename: E
authors.initials: E
authors.lastname: Nishijima
authors.forename: T
authors.initials: T
authors.lastname: Muraji
authors.forename: C
authors.initials: C
authors.lastname: Tsugawa
authors.forename: Y
authors.initials: Y
authors.lastname: Matsutmo
mesh_terms: D003106:Colon / Q000294:innervation; D003125:Colostomy / Q000379:methods; D005260:Female; D006627:Hirschsprung Disease / Q000601:surgery*; D006801:Humans; D007081:Ileostomy / Q000379:methods; D007082:Ileum / Q000294:innervation; D007223:Infant; D008297:Male; D009197:Myenteric Plexus / Q000002:abnormalities