[Phase I study of a tolmetin-paracetamol (AU-8001) ester].
A cross-over study of a tolmetin-paracetamol ester was performed on 6 healthy females. The low biodisponibility obtained might preclude its therapeutic use.
Cuena
R
R
Servicio de Farmacologia Clínica, Facultad de Medicina, Universidad de Navarra, Pamplona.
Rubio
A
A
Azanza
J R
JR
Honorato
J
J
D000082:Acetaminophen / Q000493:pharmacokinetics*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D006801:Humans; D011758:Pyrroles / Q000493:pharmacokinetics*; D014046:Tolmetin / Q000493:pharmacokinetics*
D011758:Pyrroles; D000082:Acetaminophen; D014046:Tolmetin
Estudio en fase I de un éster de tolmetín y paracetamol (AU-8001).