[A cytologic diagnosis of breast secretions--application of cytology to the mass survey of breast cancer].
From January 1982 to March 1987, an exfoliative cytological examination of abnormal nipple discharge was carried out on 790 patients. Of 22 histologically confirmed mammary carcinomas, 7 cases (31.8%) were diagnosed as positive by conventional cytologic techniques. By using the concentration method, in which the nipple secretion was collected in a series of testings that lasted 3 to 5 days and stored in a glass tube containing a fixative, the diagnostic accuracy was seen to increase significantly and 9 out of 15 malignant cases (60.0%) were accurately diagnosed as having cancer. Moreover, all 5 cases without any palpable mass were found to be positive by the smears made by this procedure.
Fujii
M
M
Clinical Laboratory, Tokyo Metropolitan Cancer Detection Center.
Ishii
Y
Y
Nagao
M
M
Wakabayashi
T
T
Fukahori
S
S
Goto
A
A
Tomono
T
T
Hagiwara
K
K
D000328:Adult; D001940:Breast / Q000378:metabolism*; D001941:Breast Diseases / Q000175:diagnosis; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D003581:Cytodiagnosis / Q000379:methods; D005260:Female; D006801:Humans; D008875:Middle Aged; D009558:Nipples / Q000378:metabolism*