title: The lateral distribution of cholesterol in the plane of lipid multibilayers.
abstract: We consider three models of cholesterol distribution in the plane of a bilayer of DMPC. We analyse recent 2H-NMR data obtained from deuterated fluorescent probes and show that, on the characteristic time-scale of 2H-NMR, it is in accord with a random distribution of cholesterol in a fluid-like DMPC bilayer in a single phase at least for T greater than or approximately equal to 35 degrees C and for 0 less than or equal to c less than or equal to 0.42.
authors.affiliation: Centre for Mathematical Simulation, St. Francis Xavier University, Antigonish, Nova Scotia, Canada.
authors.forename: D A
authors.initials: DA
authors.lastname: Pink
authors.forename: A L
authors.initials: AL
authors.lastname: MacDonald
mesh_terms: D002784:Cholesterol / Q000378:metabolism*; D004134:Dimyristoylphosphatidylcholine / Q000378:metabolism*; D004161:Diphenylhexatriene; D008051:Lipid Bilayers / Q000378:metabolism*; D008081:Liposomes / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008954:Models, Biological; D011336:Probability; D013696:Temperature
chemical_list: D008051:Lipid Bilayers; D008081:Liposomes; D004161:Diphenylhexatriene; D002784:Cholesterol; D004134:Dimyristoylphosphatidylcholine