Pulmonary Hodgkin's disease. Diagnosis by fine needle aspiration.
The cytologic manifestations of pulmonary Hodgkin's disease in transthoracic fine needle aspirates from 13 patients with pulmonary radiologic abnormalities and a previous diagnosis of Hodgkin's disease are described. Classic Reed-Sternberg cells and lacunar cells were present in most cases. The so-called "mononuclear" Reed-Sternberg cells were identified in all cases. A cellular background consisting of variable numbers of histiocytes, eosinophilic and neutrophilic leukocytes and lymphocytes was frequently present. Such a background should stimulate a search for cells diagnostic of Hodgkin's disease. We conclude that the cytologic features of Hodgkin's disease are not only characteristic, but are also diagnostic, in patients with a prior history of Hodgkin's disease in whom pulmonary recurrence is suspected.
Flint
A
A
Department of Pathology, University of Michigan Medical Center, Ann Arbor 48109-0054.
Kumar
N B
NB
Naylor
B
B
D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000473:pathology; D003581:Cytodiagnosis; D003593:Cytoplasm / Q000473:pathology; D005260:Female; D006098:Granulocytes / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006689:Hodgkin Disease / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology*; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology; D011859:Radiography