Accurate quantification of in vivo 31P NMR signals using the variable projection method and prior knowledge.
Free induction decay signals are analyzed by fitting a model function directly in the time domain. No starting values are needed for linear model parameters, and omission of corrupted data points poses no problems. A significant gain of accuracy is achieved by imposing prior knowledge about the model parameters.
van der Veen
J W
JW
Department of Applied Physics, Delft University of Technology, The Netherlands.
de Beer
R
R
Luyten
P R
PR
van Ormondt
D
D
D006801:Humans; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008962:Models, Theoretical; D010758:Phosphorus; D013997:Time Factors
D010758:Phosphorus