title: Salvage of infected total knee arthroplasty.
abstract: Between 1981 and 1986, 25 patients with 26 infected total knee arthroplasties (TKAs) were treated with complete debridement of the knee, prosthetic removal, and six weeks of intravenous antibiotics, followed by insertion of a new prosthesis. The patients were followed for 12-57 months (average, 29 months). There was no evidence of residual infection at follow-up examination in any case. Applying the Hospital for Special Surgery knee rating system, 12 patients (50%) were rated excellent, six patients (25%) good, two patients (9%) fair, and four patients (6%) poor. Of the six patients with fair and poor results, five had reduced scores due to joint problems unrelated to the infected TKA. Fourteen patients had no pain at follow-up examination, and four had only slight pain. Nine patients had no limp, ten had a slight limp, one had a moderate limp, and the remainder either had a severe limp or were bedridden due to other joint problems. Eight patients could walk an unlimited distance and four could walk at least one-half mile. Twenty-one knees had a range of flexion greater than 90 degrees. Three patients had extensor lags of 20 degrees or greater. Only one patient required bracing for ambulation.
authors.affiliation: Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612.
authors.forename: A G
authors.initials: AG
authors.lastname: Rosenberg
authors.forename: B
authors.initials: B
authors.lastname: Haas
authors.forename: R
authors.initials: R
authors.lastname: Barden
authors.forename: D
authors.initials: D
authors.lastname: Marquez
authors.forename: G C
authors.initials: GC
authors.lastname: Landon
authors.forename: J O
authors.initials: JO
authors.lastname: Galante
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001178:Arthroplasty / Q000379:methods*; D001424:Bacterial Infections / Q000188:drug therapy / Q000601:surgery*; D003646:Debridement; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000601:surgery*; D012086:Reoperation
chemical_list: D000900:Anti-Bacterial Agents