title: Deposition of endothelial fibronectin on polymeric surfaces.
abstract: Cellular fibronectin is deposited on tissue culture polystyrene during the adhesion and spreading of cultured human endothelial cells (HEC). Following the seeding of HEC upon this polymer, larger amounts of fibronectin are deposited as both cell density and incubation time increase. Our results indicate that the ability to deposit cellular fibronectin onto a polymeric surface is a condition for the spreading and proliferation of HEC.
authors.affiliation: Department of Chemical Technology, Twente University, Enschede, The Netherlands.
authors.forename: P B
authors.initials: PB
authors.lastname: van Wachem
authors.forename: T
authors.initials: T
authors.lastname: Beugeling
authors.forename: B W
authors.initials: BW
authors.lastname: Mallens
authors.forename: A
authors.initials: A
authors.lastname: Dekker
authors.forename: J
authors.initials: J
authors.lastname: Feijen
authors.forename: A
authors.initials: A
authors.lastname: Bantjes
authors.forename: W G
authors.initials: WG
authors.lastname: van Aken
mesh_terms: D000327:Adsorption; D001672:Biocompatible Materials; D002448:Cell Adhesion; D002455:Cell Division; D002478:Cells, Cultured; D003470:Culture Media; D046508:Culture Techniques; D004730:Endothelium, Vascular / Q000166:cytology / Q000502:physiology*; D005353:Fibronectins / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D011108:Polymers; D011137:Polystyrenes; D014471:Umbilical Veins
chemical_list: D001672:Biocompatible Materials; D003470:Culture Media; D005353:Fibronectins; D011108:Polymers; D011137:Polystyrenes