title: Amikacin-acetyltransferase (AAC-6'/I) encoded by an IncH2 plasmid (pIE866) in Escherichia coli strains.
abstract: An amikacin resistance plasmid was detected in E. coli wild type strains isolated from polluted surface water. This conjugative 145 Md plasmid belongs to the IncH2 group and specifies amino-glycoside-acetyltransferase AAC-6'/I activity.
authors.affiliation: Institut für Experimentelle Epidemiologie, Wernigerode, DDR.
authors.forename: W
authors.initials: W
authors.lastname: Voigt
authors.forename: H
authors.initials: H
authors.lastname: Tschäpe
authors.forename: H
authors.initials: H
authors.lastname: Heier
mesh_terms: D000123:Acetyltransferases / Q000235:genetics*; D000583:Amikacin / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D011815:R Factors; D013379:Substrate Specificity; D014871:Water Microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000583:Amikacin; D000123:Acetyltransferases; C056532:aminoglycoside N(6')-acetyltransferase