[Desensitization for 4 successive years using calcium phosphate-adsorbed pollen extracts: study of sera with RAST and PRIST immunoimprints].
The clinical study for four years running of desensitization treatment to adsorbed pollen calcium phosphate, prepared "at request" by Institut Pasteur, shows that these preparations produced particularly good results. The population of allergic subjects is divided into two categories as from first year of treatment: good responders and non responders. A study on the serums of these patients, in view of a different "immuno-imprint" in these two groups, has not yet been conclusive, whereas we were expecting much from this prognosis test, which would have given us better treatment information.
Donat
N
N
Thibaudon
M
M
Peltre
G
G
David
B
B
D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000008:administration & dosage*; D002130:Calcium Phosphates; D002986:Clinical Trials as Topic; D003888:Desensitization, Immunologic / Q000379:methods*; D005260:Female; D006801:Humans; D007164:Immunosorbents; D008297:Male; D008875:Middle Aged; D011058:Pollen / Q000276:immunology*; D011852:Radioallergosorbent Test; D011863:Radioimmunoassay; D011864:Radioimmunosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology / Q000628:therapy*
D000485:Allergens; D002130:Calcium Phosphates; D007164:Immunosorbents; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous
Désensibilisation par des extraits de pollen adsorbés sur phosphate de calcium pendant 4 années consécutives: étude des sérums par immunoempreintes, RAST et PRIST.