Cyclic neutropenia terminating in permanent agranulocytosis.
A patient with cyclic neutropenia was followed for 20 years. After 16 years she developed a permanent agranulocytosis, and lived for nearly four years without neutrophils in the peripheral blood. Neither prednisone, lithium nor leuco- and plasmapheresis had any effect on the neutrophil count.
Boesen
P
P
Department of Internal Medicine and Haematology, Aalborg Hospital, Denmark.
D000293:Adolescent; D000380:Agranulocytosis / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008875:Middle Aged; D009503:Neutropenia / Q000097:blood / Q000175:diagnosis*; D010507:Periodicity