title: Failure of diterpenes from Jatropha curcas to induce mutation in Salmonella typhimurium TA98 and TA100.
abstract: No mutagenicity of five diterpenes isolated from the roots of Jatropha curcas was detected by Ame's test using both TA98 and TA100 tester strains with or without S-9 fraction from livers of rats treated with polychlorinated biphenyl.
authors.affiliation: Research Division, National Cancer Institute, Bangkok, Thailand.
authors.forename: W
authors.initials: W
authors.lastname: Rojanapo
authors.forename: J
authors.initials: J
authors.lastname: Pimbua
authors.forename: T
authors.initials: T
authors.lastname: Glinsukon
authors.forename: W
authors.initials: W
authors.lastname: Naengchomnong
authors.forename: Y
authors.initials: Y
authors.lastname: Thebtaranonth
mesh_terms: D000818:Animals; D001711:Biotransformation; D004224:Diterpenes / Q000493:pharmacokinetics / Q000633:toxicity*; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens / Q000493:pharmacokinetics; D010946:Plants, Medicinal / Q000032:analysis*; D051381:Rats; D012486:Salmonella typhimurium / Q000235:genetics
chemical_list: D004224:Diterpenes; D009153:Mutagens