title: Malignant transformation in craniopharyngioma.
abstract: Malignant transformation in a craniopharyngioma has not been described previously. A 49-year-old woman presented with recurrence of a suprasellar craniopharyngioma diagnosed 35 years previously. The patient had been treated surgically for recurrence on five occasions. Radiation therapy had been administered 7 years before the final presentation. Tissue obtained from the fifth operation revealed malignant degeneration in a typical craniopharyngioma.
authors.affiliation: Department of Pathology, University of South Alabama Medical Center, Mobile.
authors.forename: G A
authors.initials: GA
authors.lastname: Nelson
authors.forename: F O
authors.initials: FO
authors.lastname: Bastian
authors.forename: M
authors.initials: M
authors.lastname: Schlitt
authors.forename: R L
authors.initials: RL
authors.lastname: White
mesh_terms: D003397:Craniopharyngioma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010911:Pituitary Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery