Neuroleptic malignant syndrome following amoxapine overdose.
The case of a patient who developed the neuroleptic malignant syndrome following an overdose of amoxapine is presented. It is suggested that amoxapine, an antidepressant structurally related to the neuroleptic loxapine, be added to the list of medications that can cause this potentially lethal syndrome. This case illustrates the need for careful evaluation and attention to differential diagnosis when psychiatric patients develop physical signs and symptoms.
Taylor
N E
NE
Department of Psychiatry, Beth Israel Medical Center, New York, New York 10003.
Schwartz
H I
HI
D000328:Adult; D000657:Amoxapine / Q000506:poisoning*; D001480:Basal Ganglia Diseases / Q000175:diagnosis; D002389:Catatonia / Q000175:diagnosis; D003937:Diagnosis, Differential; D003989:Dibenzoxazepines / Q000506:poisoning*; D005260:Female; D006801:Humans; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000209:etiology*; D013406:Suicide, Attempted / Q000523:psychology
D003989:Dibenzoxazepines; D000657:Amoxapine