title: Molecular genetic approaches to the analysis of human ophthalmic disease.
abstract: In this review of the recent literature, the contribution that the new techniques of molecular genetics has made in the analysis and diagnosis of human ophthalmic conditions is presented and discussed. Among the disorders reviewed are X-linked retinitis pigmentosa, Norrie's disease, gyrate atrophy and retinoblastoma, and there are also sections on crystallins and visual pigments.
authors.affiliation: Haematology Department, King's College Hospital School of Medicine, Denmark Hill, London.
authors.forename: D N
authors.initials: DN
authors.lastname: Cooper
authors.forename: M
authors.initials: M
authors.lastname: Jay
authors.forename: S
authors.initials: S
authors.lastname: Bhattacharya
authors.forename: B
authors.initials: B
authors.lastname: Jay
mesh_terms: D002874:Chromosome Mapping; D003459:Crystallins / Q000235:genetics; D004274:DNA, Recombinant; D005128:Eye Diseases / Q000235:genetics*; D005134:Eye Neoplasms / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008967:Molecular Biology; D012168:Retinal Pigments / Q000235:genetics; D012174:Retinitis Pigmentosa / Q000235:genetics; D012175:Retinoblastoma / Q000235:genetics; D014785:Vision, Ocular
chemical_list: D003459:Crystallins; D004274:DNA, Recombinant; D012168:Retinal Pigments