title: No relevant influence on overall survival time in patients with metastatic breast cancer undergoing combination chemotherapy.
abstract: The results of clinical studies dealing with first and second line chemotherapy of metastatic breast cancer published between 1975 and early 1986 which involved 9350 women were reviewed. Our special aim was to evaluate combination chemotherapy and its influence on overall survival in late stage breast cancer patients. No significant improvement in overall survival times was found in this selected group of patients who were treated with intense palliative chemotherapy.
authors.affiliation: Institute of Toxicology and Chemotherapy, German Cancer Research Center, Heidelberg.
authors.forename: E
authors.initials: E
authors.lastname: Petru
authors.forename: D
authors.initials: D
authors.lastname: Schmähl
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000401:mortality; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis