Absorbable synthetic mesh (910-polyglactin) intestinal sling to reduce radiation-induced small bowel injury in patients with pelvic malignancies.
Absorbable synthetic mesh (910-polyglactin) was used to create an intestinal sling in six patients undergoing surgical staging of pelvic malignancies prior to radiation therapy. All patients had effective compartmentalization of small intestine out of the pelvis which persisted throughout the duration of radiation therapy. None of the patients developed complications related to the intestinal sling. This technique is well tolerated and has the potential to minimize chronic small intestinal complications caused by radiation therapy for pelvic malignancies.
Soper
J T
JT
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina 27710.
Clarke-Pearson
D L
DL
Creasman
W T
WT
D000368:Aged; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000517:prevention & control*; D007421:Intestine, Small / Q000528:radiation effects; D008875:Middle Aged; D011098:Polyglactin 910; D011108:Polymers; D011832:Radiation Injuries / Q000517:prevention & control*; D013526:Surgical Mesh; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D014594:Uterine Neoplasms / Q000532:radiotherapy* / Q000601:surgery
D011108:Polymers; D011098:Polyglactin 910