title: Spontaneous subclavian vein thrombosis: a successful combined approach of local thrombolytic therapy followed by first-rib resection.
abstract: In 17% to 74% of patients with subclavian vein thrombosis, conservative treatment or venous thrombectomy led to residual symptoms. To improve these results, a prospective study was started in patients with subclavian vein thrombosis who were treated with a combined approach of local thrombolytic therapy followed by a first-rib resection. From 1983 to 1987 five patients entered the protocol. Total lysis was achieved in all cases. In the follow-up period, phlebography and strain-gauge plethysmography according to Whitney showed no recurrent thrombosis. All patients were able to resume their normal activities.
authors.affiliation: Department of Surgery, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Rauwerda
authors.forename: F C
authors.initials: FC
authors.lastname: Bakker
authors.forename: T A
authors.initials: TA
authors.lastname: van den Broek
authors.forename: B J
authors.initials: BJ
authors.lastname: Dwars
mesh_terms: D000328:Adult; D002404:Catheterization; D005260:Female; D005500:Follow-Up Studies; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D010991:Plethysmography; D011446:Prospective Studies; D012272:Ribs / Q000601:surgery*; D013300:Streptokinase / Q000008:administration & dosage*; D013350:Subclavian Vein; D013927:Thrombosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy*
chemical_list: D006493:Heparin; D013300:Streptokinase