The structure of the neuraminic acid-containing capsular polysaccharide of Escherichia coli serotype K9.
The acidic capsular polysaccharide isolated from Escherichia coli O9:K9:H12 was investigated by using n.m.r. spectroscopy, methylation analysis, periodate oxidation, and bacteriophage-borne enzyme degradation. The polysaccharide, the structure of which is shown below, is the third E. coli capsular polysaccharide reported to contain neuraminic acid, the others being the K1 and K92 polysaccharides, and it is the first in the E. coli series shown to contain a 4-linked neuraminic acid unit. (formula; see text).
Dutton
G G
GG
Department of Chemistry, University of British Columbia, Vancouver, Canada.
Parolis
H
H
Parolis
L A
LA
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D004926:Escherichia coli / Q000276:immunology*; D008401:Gas Chromatography-Mass Spectrometry; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009438:Neuraminic Acids / Q000032:analysis*; D011135:Polysaccharides, Bacterial; D012703:Serotyping
D007202:Indicators and Reagents; D009438:Neuraminic Acids; D011135:Polysaccharides, Bacterial