title: [A case report of carcinoid of the rectum coexisting with adenocarcinoma in a single lesion].
abstract: A 69-year-old female, chiefly complaining of diarrhea, was admitted to the Toyama Medical & Pharmaceutical University Hospital. A barium enema and an endoscopic examination revealed a villous adenocarcinoma of the rectum. Computerized tomography disclosed multiple metastatic lesions in the liver. She underwent an amptatio recti and an intra-arterial cannulation of the common hepatic artery in order to administer anticancer agents. Gross findings of the resected specimen showed villous adenocarcinoma containing a small ulcerated lesion. Histologic findings of this lesion revealed a collision neoplasm containing both an adenocarcinoma and a carcinoid with no obvious transitional region between the two lesions. The type D carcinoid, determined according to Soga's histologic classification, showed positive argyrophil granules but no argentaffin granules in the cytoplasm. The electron-microscopic findings of the carcinoid revealed small electron-dense endocrine granules measuring about 150 approximately 300 nm in diameter. The woman died 4 months after this operation.
authors.affiliation: 2nd Dept. of Surgery, Toyama Med. & Pharma. Univ.
authors.forename: Y
authors.initials: Y
authors.lastname: Karaki
authors.forename: K
authors.initials: K
authors.lastname: Tazawa
authors.forename: K
authors.initials: K
authors.lastname: Fumoto
authors.forename: T
authors.initials: T
authors.lastname: Kushibuchi
authors.forename: M
authors.initials: M
authors.lastname: Saitoh
authors.forename: M
authors.initials: M
authors.lastname: Sawataishi
authors.forename: T
authors.initials: T
authors.lastname: Saeki
authors.forename: S
authors.initials: S
authors.lastname: Munakata
authors.forename: M
authors.initials: M
authors.lastname: Fujimaki
authors.forename: T
authors.initials: T
authors.lastname: Bando
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D000368:Aged; D002276:Carcinoid Tumor / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery