Endothelial cell xanthine oxidase-derived toxic oxygen metabolites contribute to acute lung injury from neutrophil elastase.
Rodell
T C
TC
Department of Medicine, University of Colorado Health Sciences Center, Webb-Waring Lung Institute, Denver.
Cheronis
J C
JC
Repine
J E
JE
D000818:Animals; D004730:Endothelium, Vascular / Q000187:drug effects / Q000201:enzymology*; D008168:Lung / Q000187:drug effects / Q000378:metabolism; D055370:Lung Injury; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology*; D010100:Oxygen / Q000378:metabolism / Q000633:toxicity*; D010196:Pancreatic Elastase / Q000378:metabolism; D014414:Tungsten / Q000494:pharmacology; D014969:Xanthine Oxidase / Q000378:metabolism*
D014969:Xanthine Oxidase; D010196:Pancreatic Elastase; D010100:Oxygen; D014414:Tungsten