title: Melorheostosis: two case presentations and review of the literature.
abstract: Two cases are presented. Case #1, a 27-year-old Caucasian male presented with chronic right leg pain. Case 2 was a 23-year-old Caucasian female with right fifth finger pain. The clinical examination was benign except for mild tenderness of many years duration. No deformities were present in the male patient, the female patient did exhibit mild clinodactyly. The pain was described as constant, low grade, and dull. Plain roentgenograms of both patients demonstrated a hyperostotic process typical of melorheostosis and the bone scans demonstrated increased bone activity. A CAT scan demonstrated both endosteal and periosteal hyperostosis in our male patient. The biopsies of both patients were consistent with the clinical diagnosis of melorheostosis. A discussion and review of the literature covering this process is presented.
authors.affiliation: Department of Orthopedics, USAF Regional Hospital, Minot Air Force Base, North Dakota.
authors.forename: J R
authors.initials: JR
authors.lastname: Dimar
authors.forename: T S
authors.initials: TS
authors.lastname: Campion
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D005385:Fingers / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008557:Melorheostosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D011877:Radionuclide Imaging; D013977:Tibia / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D000893:Anti-Inflammatory Agents