Brain shrinkage in alcoholics is not caused by changes in hydration: a pathological study.
Measurement of the water content of the cerebral white matter in 26 control and 24 alcoholic cases supports in vivo MRI studies and previous necropsy studies which appeared to show an increase in the water content in the alcoholic group. This negates the hypothesis that reversible brain shrinkage in alcoholics is caused by changes in the state of hydration.
Harper
C G
CG
Department of Pathology, University of Sydney, Australia.
Kril
J J
JJ
Daly
J M
JM
D000368:Aged; D000437:Alcoholism / Q000473:pathology*; D001284:Atrophy; D001921:Brain / Q000473:pathology*; D001929:Brain Edema / Q000473:pathology; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000473:pathology; D008875:Middle Aged; D014882:Water-Electrolyte Balance; D014899:Wernicke Encephalopathy / Q000473:pathology