title: [Preliminary study on the antimutagenesis of vegetables and fruits].
abstract: Possible antimutation of 108 preparations of 91 kinds of vegetables and fruits on Salmonella typhimurium TA98 and TA100 mutants was tested. 4-nitroquinoline-N-oxide (4 NQO), N-methyl-N-nitro-N-nitrosoguanidine (MNNG), aflatoxin B1 (AFB1) and benzo (a) pyrene (BaP) were used as mutagens. The results showed that 67 (62%) preparations had antimutagenic action in vitro to different degrees. 9.6% of all preparations showed inhibition action on 4 NQO in TA100 mutant and 12.3%, in TA98, 5% on MNNG in TA100, 38% on AFB1 in TA100 and 45.1% in TA98, 28.9% on BaP in TA100. This experiment provides a scientific basis to the study of food resources as prevention of carcinogenesis.
authors.affiliation: Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
authors.forename: H Z
authors.initials: HZ
authors.lastname: Luo
authors.forename: S J
authors.initials: SJ
authors.lastname: Cheng
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Jang
authors.forename: N J
authors.initials: NJ
authors.lastname: Han
authors.forename: X Q
authors.initials: XQ
authors.lastname: Li
authors.forename: S Y
authors.initials: SY
authors.lastname: Yie
authors.forename: J L
authors.initials: JL
authors.lastname: Liang
mesh_terms: D000818:Animals; D005638:Fruit; D008297:Male; D009152:Mutagenicity Tests / Q000379:methods; D009154:Mutation; D051381:Rats; D012486:Salmonella typhimurium / Q000235:genetics; D014675:Vegetables