title: Transcutaneous oxygen and carbon dioxide pressure monitoring to determine severity of limb ischemia and to predict surgical outcome.
abstract: Transcutaneous oxygen and carbon dioxide pressure (PO2 and PCO2) foot monitoring was compared with ankle Doppler-derived systolic pressure regarding their respective abilities to discriminate the severity of limb ischemia before vascular reconstruction and to predict surgical outcome early in the postoperative period. Transcutaneous PO2 (tcPCO2), foot-chest tcPO2 index, transcutaneous PCO2 (tcPCO2), foot tcPO2/tcPCO2 index (tcPO2/tcPCO2), ankle Doppler systolic pressure (AP), and ankle-brachial pressure index (ABI) were determined in 89 revascularized limbs. The measurement of tcPO2 and foot-chest tcPO2 was found to be more sensitive to degrees of severity of limb ischemia and more closely associated with the outcome of revascularization than AP and ABI. TcPCO2 and tcPO2/tcPCO2 were not useful in assessment of the vascular patient undergoing reconstructive surgery. Before operation, tcPO2 less than or equal to 22 torr and foot-chest tcPO2 less than or equal to 0.46 indicate severe limb ischemia requiring urgent revascularization. After operation, tcPO2 less than or equal to 22 torr and foot-chest tcPO2 index less than or equal to 0.53 indicate that revascularization is likely to fail. We conclude that tcPO2 monitoring, as a metabolic test of actual tissue perfusion, is a more reliable indicator of preoperative limb ischemia and postoperative outcome of revascularization than hemodynamic, Doppler-derived pressure tests.
authors.affiliation: University of Arizona/Tucson Veterans Administration Medical Center.
authors.forename: S G
authors.initials: SG
authors.lastname: Lalka
authors.forename: J M
authors.initials: JM
authors.lastname: Malone
authors.forename: G G
authors.initials: GG
authors.lastname: Anderson
authors.forename: R M
authors.initials: RM
authors.lastname: Hagaman
authors.forename: K E
authors.initials: KE
authors.lastname: McIntyre
authors.forename: V M
authors.initials: VM
authors.lastname: Bernhard
mesh_terms: D000368:Aged; D001785:Blood Gas Monitoring, Transcutaneous; D001795:Blood Pressure Determination; D003925:Diabetic Angiopathies / Q000097:blood* / Q000601:surgery; D006801:Humans; D007383:Intermittent Claudication / Q000097:blood* / Q000601:surgery; D007511:Ischemia; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged