The pathobiology of proto-oncogenes.
The search for genetic damage in neoplastic cells now occupies a central place in cancer research. Diverse examples of such damage are in hand, and they in turn hint at biochemical explanations of why cancer cells go astray. The way may be open to solve the riddles of how normal cells govern their replication and why cancer cells do not.
Bishop
J M
JM
Department of Microbiology and Immunology, University of California Medical Center, San Francisco 94143.
D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D011519:Proto-Oncogenes