[Immunofluorescence in the determination of gliadin antibodies in celiac disease].
IgG gliadin antibodies (AGA-IgG) were detected by immunofluorescence in 78 celiac children diagnosed by jejunal biopsy. AGA-IgG were also detected in patients affected by other gastrointestinal disease, in patients with diabetes, in health children and in children with normal mucosa. AGA-IgG were found in 81% of celiac patients, while they were not detected in patients affected by other intestinal or extraintestinal diseases, neither in healthy controls. It is conclude that determination of AGA-IgG is a very specific and sensitive enough screening test before small intestinal biopsy.
Castro
M
M
Ospedale Bambino Gesù, Servizio di Gastroenterologia e Nutrizione, Roma, Italia.
Castellucci
G
G
Papadatou
B
B
Bragetti
P
P
Ferretti
F
F
Maggi
S
S
Lucidi
V
V
Poletti
C
C
D000293:Adolescent; D000367:Age Factors; D000906:Antibodies / Q000032:analysis*; D002446:Celiac Disease / Q000175:diagnosis / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005455:Fluorescent Antibody Technique; D005903:Gliadin / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007223:Infant; D010940:Plant Proteins / Q000276:immunology*
D000906:Antibodies; D007074:Immunoglobulin G; D010940:Plant Proteins; D005903:Gliadin
Il dosaggio degli anticorpi antigliadina con immunofluorescenza nella malattia celiaca.