title: [Activated oncogenes in human tumors].
abstract: ras oncogenes are cellular genes altered by point mutation in 10 to 30% of human tumors. Under this mutated form they play a role in the malignant process, probably in association with other oncogenes. The different ras genes identified in human cancers, the point mutations that activate the ras genes and the properties of the ras proteins are described.
authors.affiliation: Unité 119 de l'INSERM, Marseille, France.
authors.forename: T
authors.initials: T
authors.lastname: Noguchi
authors.forename: J
authors.initials: J
authors.lastname: Adelaide
authors.forename: I
authors.initials: I
authors.lastname: Marics
authors.forename: F
authors.initials: F
authors.lastname: Raybaud
authors.forename: O
authors.initials: O
authors.lastname: de Lapeyrière
authors.forename: D
authors.initials: D
authors.lastname: Birnbaum
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D003062:Codon / Q000235:genetics; D004273:DNA, Neoplasm / Q000235:genetics; D005786:Gene Expression Regulation; D011905:Genes, ras; D006801:Humans; D051379:Mice; D008957:Models, Genetic; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D051381:Rats; D014162:Transfection; D014407:Tumor Cells, Cultured
chemical_list: D003062:Codon; D004273:DNA, Neoplasm
vernacular_title: Les oncogènes ras activés dans les tumeurs humaines.