title: The amniotic band disruption complex. The pathogenesis of congenital limb ring-constrictions; an experimental study in the foetal rat.
abstract: This paper reports the findings of an experimental foetal rat study which has shown that it is possible to produce mild, moderate and severe limb ring-constrictions by simulating the ligature effect of amniotic bands. Of the 40 experimental foetuses, 36 (90%) survived the in utero surgery and are included in the present study. Of these 36 foetuses, limb constriction rings were produced in 35 (97%), and an in utero limb amputation in one (3%).
authors.affiliation: Department of Plastic Surgery, Radcliffe Infirmary, Oxford.
authors.forename: A R
authors.initials: AR
authors.lastname: Rowsell
mesh_terms: D000652:Amniotic Band Syndrome / Q000209:etiology* / Q000473:pathology; D000818:Animals; D003250:Constriction; D005260:Female; D005333:Fetus; D006801:Humans; D007231:Infant, Newborn; D008026:Ligation; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains