HLA and schizophrenia in Israel.
Thirty-two Israeli Jewish schizophrenic patients were typed for Class I (HLA-A, B, C) and Class II (HLA-DR) antigens. A significant increase of HLA-A2 (P = 0.01) and A23 (P = 0.02) was found. None of the 10 HLA-DR antigens tested was associated with the disease. Study of eight families indicated that close linkage of the gene responsible for this disorder to the HLA system is unlikely.
Amar
A
A
Department of Clinical Microbiology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Zohar
M
M
Tiwari
J
J
Brautbar
C
C
D000328:Adult; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007557:Israel; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000235:genetics*
D006680:HLA Antigens; D006684:HLA-DR Antigens