title: [Polyploidization dynamics of tertiary trophoblast giant cells in the rat placenta].
abstract: Polyploidization peculiarities of tertiary giant trophoblast cells during their active detaching from the ectoplacental cone and migrating into decidua basalis are investigated. On the 12th day of gestation, the ploidy of the majority of cell nuclei varies within 4-8c, although there are a few 16c and 32c nuclei. On the 13th and 14th days of gestation, the ploidy level of tertiary giant trophoblast cells enhances; 8c and 16c nuclei prevail, the percentage of 32c nuclei increases, 64c nuclei arising. The ploidy level of tertiary giant cell coincides with the average and/or maximum ploidy degree of precursor cell populations. The significance of polyploidy as indispensable condition of differentiation of the trophoblast cells that actively invade into maternal tissues is discussed.
authors.forename: T G
authors.initials: TG
authors.lastname: Zybina
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D003584:Cytological Techniques; D005260:Female; D010920:Placenta / Q000166:cytology*; D011123:Polyploidy; D011247:Pregnancy; D051381:Rats; D013997:Time Factors; D014327:Trophoblasts / Q000166:cytology*
vernacular_title: Dinamika poliploidizatsii tretichnykh gigantskikh kletok trofoblasta v platsente krysy.