title: Radionuclide ventriculography: II. Anatomic and physiologic aspects.
abstract: Radionuclide ventriculography is a widely applied noninvasive technique for the assessment of global and regional ventricular function. In this manuscript, the second of a two-part review of radionuclide ventriculography, the analysis of the images provided by these studies and their clinical applications are discussed. A description of the anatomic information that may be gleaned from the evaluation of the size and shape of the cardiac blood pool and the contiguous vessels is included. The quantitative methods available for the analysis of radionuclide ventriculograms and the several variables that may be measured are discussed. These methods include measurements of global and regional systolic ventricular function and of global diastolic ventricular function. Finally, the clinical applications of radionuclide ventriculography are described. These applications include the diagnosis of coronary artery disease, both acute and chronic, and evaluations of prognosis and therapeutic response in patients with coronary artery disease, valvular heart disease, especially regurgitant lesions, and myopathic heart diseases, particularly dilated and hypertrophic cardiomyopathies.
authors.affiliation: Department of Radiology, University of Texas Health Science Center, Dallas 75235.
authors.forename: J R
authors.initials: JR
authors.lastname: Corbett
authors.forename: D E
authors.initials: DE
authors.lastname: Jansen
authors.forename: J T
authors.initials: JT
authors.lastname: Willerson
mesh_terms: D006321:Heart / Q000033:anatomy & histology / Q000000981:diagnostic imaging* / Q000502:physiology; D006334:Heart Function Tests / Q000379:methods*; D006801:Humans; D011877:Radionuclide Imaging