Familial meningiomas. Report of two cases.
The Authors report a case of intracranial meningioma in two sisters, with no evidence of neurofibromatosis. A study of the karyotype has been performed; in one patient we have found a pericentric inversion of one chromosome 9. The possible role of the genetical factors in the develop of familial meningiomas is discussed.
Ferrante
L
L
Department of Neurological Sciences, University of Rome La Sapienza, Italy.
Acqui
M
M
Mastronardi
L
L
Nucci
F
F
D000328:Adult; D002869:Chromosome Aberrations; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D007621:Karyotyping; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics*; D008579:Meningioma / Q000000981:diagnostic imaging / Q000235:genetics*; D014057:Tomography, X-Ray Computed