Persistent neonatal hyperinsulinism.
Over a 3-year period, the diagnosis of persistent neonatal hyperinsulinism (PNH) was made in seven infants, from an unselected cohort of 18,726 births, all of Saudi Arabian origin. Thus the incidence of PNH was one in 2,675 births. The high incidence, associated consanguinity, and occurrence in siblings suggest that PNH may be inherited as an autosomal recessive disorder.
Mathew
P M
PM
Department of Paediatrics, Dhahran Health Center, Saudi Arabia.
Young
J M
JM
Abu-Osba
Y K
YK
Mulhern
B D
BD
Hammoudi
S
S
Hamdan
J A
JA
Sa'di
A R
AR
D003241:Consanguinity; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications / Q000151:congenital* / Q000453:epidemiology / Q000235:genetics; D007003:Hypoglycemia / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D012529:Saudi Arabia