[Activated oncogenes in human tumors].
ras oncogenes are cellular genes altered by point mutation in 10 to 30% of human tumors. Under this mutated form they play a role in the malignant process, probably in association with other oncogenes. The different ras genes identified in human cancers, the point mutations that activate the ras genes and the properties of the ras proteins are described.
Noguchi
T
T
Unité 119 de l'INSERM, Marseille, France.
Adelaide
J
J
Marics
I
I
Raybaud
F
F
de Lapeyrière
O
O
Birnbaum
D
D
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D003062:Codon / Q000235:genetics; D004273:DNA, Neoplasm / Q000235:genetics; D005786:Gene Expression Regulation; D011905:Genes, ras; D006801:Humans; D051379:Mice; D008957:Models, Genetic; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D051381:Rats; D014162:Transfection; D014407:Tumor Cells, Cultured
D003062:Codon; D004273:DNA, Neoplasm
Les oncogènes ras activés dans les tumeurs humaines.