title: Personality pathology in recurrent depression: nature, prevalence, and relationship to treatment response.
abstract: Personality assessments of 119 treatment-responsive patients with recurrent unipolar depression revealed that nearly half of the patients (48%) showed some personality disturbance. The most common personality features were avoidant (30.4%), compulsive (18.6%), and dependent (15.7%). Factor analyses of personality data in this homogeneous population yielded results that were consistent with previous factor analytic studies of personality features and clinical descriptions of depressed patients. Most notably, a discriminant function analysis using personality variables alone was able to distinguish (with 65% accuracy) between patients who responded normally to treatment and those who responded more slowly.
authors.affiliation: Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213.
authors.forename: P A
authors.initials: PA
authors.lastname: Pilkonis
authors.forename: E
authors.initials: E
authors.lastname: Frank
mesh_terms: D000328:Adult; D000368:Aged; D003866:Depressive Disorder / Q000150:complications* / Q000523:psychology / Q000628:therapy; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care; D010552:Personality Assessment; D010554:Personality Disorders / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D011613:Psychotherapy; D012008:Recurrence
chemical_list: D007099:Imipramine