[Toxicologic evaluation of individual chemical compounds and complex mixtures using a motile cell test object].
The possibility of quantitative prognosis of chemical compounds and complex mixtures toxicity by means of a biotechnical system with suspension of bull spermatozoa sensor was investigated. The concentration of some chemical compounds, inhibiting by half spermatozoa motility has been experimentally determined. A correlation between the values determined and acute toxicity of the compounds tested has been established. The possible use of the biotechnical system for the screening of medical polymer materials has been demonstrated.
Kaiumov
R I
RI
Es'kov
A P
AP
Aref'ev
I M
IM
Lappo
V G
VG
Rotenberg
Iu S
IuS
D000818:Animals; D002417:Cattle; D008297:Male; D011108:Polymers / Q000633:toxicity; D013081:Sperm Motility / Q000187:drug effects*; D014116:Toxicology / Q000379:methods*
D011108:Polymers
Toksikologicheskaia otsenka individual'nykh khimicheskikh soedineniĭ i smeseĭ slozhnogo sostava s ispol'zovaniem podvizhnogo kletochnogo test-ob"ekta.