title: Acceleration-induced electrocardiographic interval changes.
abstract: The electrocardiographic intervals (PR, QRS, QT, and RR) before, during, and post +Gz stress were measured in 24 healthy male subjects undergoing +Gz centrifuge exposure. The PR and QRS intervals responded in a predictable manner, shortening during stress and returning to baseline resting values post-stress. The QT interval, however, was not observed to be dependent solely on heart rate. Bazett's formula, which was developed to correct for heart rate variability, did not adequately result in a homogeneous correction of the QT interval for each stress-related period. During +Gz stress, the QT was shortened, and the QTc prolonged. The QT interval remained shortened even though the heart rate returned to baseline (with the QTc undercorrected) in the post-stress period. The QT (QTc) interval variations probably reflect the effects of both heart rate and autonomic balance during and after +Gz stress, and may provide a measure of the prevailing autonomic (sympathetic or parasympathetic) tone existing at a given point associated with +Gz stress. These electrocardiographic interval changes define the normal response for healthy individuals. Individuals with exaggerated autonomic responses could be identified by comparing their responses to these normal responses resulting from +Gz stress.
authors.affiliation: USAF Academy, Colorado Springs, Colorado.
authors.forename: C C
authors.initials: CC
authors.lastname: Whinnery
authors.forename: J E
authors.initials: JE
authors.lastname: Whinnery
mesh_terms: D000054:Acceleration; D000337:Aerospace Medicine; D004562:Electrocardiography; D006339:Heart Rate; D006801:Humans; D008297:Male