title: Pathologic fractures of the humerus.
abstract: In a study of 57 actual or impending pathologic fractures of the humerus in 52 patients with inoperable cancer treated between 1972 and 1982, we retrospectively reviewed the charts for analysis and comparison of the functional result and pain relief afforded by the various treatments used. Function of the extremity and relief of pain were each graded as excellent, good, fair, or poor using a modification of Perez's rating system. Seven pathologic fractures were treated nonoperatively. These patients generally had only fair pain relief and a poor functional result. Forty-six pathologic fractures were treated with intramedullary fixation using a Rush rod (n = 16), a Küntscher rod (n = 29), or an Ender rod (n = 1); the Neer endoprosthesis was used in four patients. Thirty-one patients received radiation to the humerus. There were seven operative complications, the most common (n = 3) being prominence of an intramedullary rod at the insertion site which required a second minor procedure for advancement of the rod. From this series, we conclude that any patient who has a pathologic fracture or impending fracture of the humerus and a predicted survival of six weeks or more is likely to benefit from rigid internal fixation with an appropriately selected device, adjunctive use of methylmethacrylate, and postoperative local irradiation therapy as needed.
authors.affiliation: Department of Surgery, Bowman Gray School of Medicine, Wake Forest University Medical Center, Winston-Salem, NC 27103.
authors.forename: J M
authors.initials: JM
authors.lastname: Lancaster
authors.forename: L A
authors.initials: LA
authors.lastname: Koman
authors.forename: A G
authors.initials: AG
authors.lastname: Gristina
authors.forename: G D
authors.initials: GD
authors.lastname: Rovere
authors.forename: G G
authors.initials: GG
authors.lastname: Poehling
authors.forename: J F
authors.initials: JF
authors.lastname: Nicastro
authors.forename: D M
authors.initials: DM
authors.lastname: Adair
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000150:complications / Q000556:secondary; D005260:Female; D005594:Fracture Fixation, Intramedullary / Q000009:adverse effects; D005598:Fractures, Spontaneous / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D006801:Humans; D006810:Humeral Fractures / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D007103:Immobilization; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D012784:Shoulder Fractures / Q000209:etiology / Q000601:surgery / Q000628:therapy