DSM-III personality disorders and family history of mental illness.
This report investigates the way in which the presence of a personality disorder (PD) in probands affects the frequency of psychiatric disorders in relatives. Four proband groups--panic, panic plus a PD, major depression, and depression plus a PD--were given the Family History-Research Diagnostic Criteria and the Family History for DSM-III Anxiety and Personality Disorders. Information was gathered on 730 first-degree relatives. Panic patients with a PD had higher incidences of panic and panic plus a PD in relatives. There was increased depression in relatives of probands with either depression or a PD. Alcoholism appeared highest in relatives of probands who had combined depression and a PD.
Reich
J
J
Department of Psychiatry, University of Iowa College of Medicine.
D000437:Alcoholism / Q000235:genetics; D001008:Anxiety Disorders / Q000235:genetics; D003866:Depressive Disorder / Q000235:genetics; D006801:Humans; D001523:Mental Disorders / Q000235:genetics*; D010200:Panic; D010554:Personality Disorders / Q000235:genetics*; D011569:Psychiatric Status Rating Scales