Chloramphenicol pretreatment enhances resistance to UV, X-rays and H2O2 damage in Escherichia coli but not of infecting UV-damaged phages.
Chloramphenicol pretreatment of Escherichia coli increases resistance to UV, X-rays and H2O2 damage. Increased survival of UV-irradiated, infecting lambda phages is not observed. The hypothesis that enhanced survival of chloramphenicol-pretreated cells is due to the induction of plasmid "repairons" is questioned.
Fernandes
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PM
Departamento de Radiobiologia, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Brasil.
Carvalho
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RE
Leitão
A C
AC
D002701:Chloramphenicol / Q000494:pharmacology*; D004249:DNA Damage; D004926:Escherichia coli / Q000528:radiation effects*; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D014466:Ultraviolet Rays
D002701:Chloramphenicol; D006861:Hydrogen Peroxide