title: Severe anaphylactoid reaction to nalidixic acid.
abstract: We present the case of a 58-year-old non-atopic woman who suffered an adverse reaction to orally administered nalidixic acid, which had been prescribed for the treatment of a urinary tract infection. The single-blind oral provocation test was positive; the patient presented the clinical features of an anaphylactoid reaction 3 min after administration of nalidixic acid. Both the skin test and the histamine release test were negative. These results suggest that we are dealing with an anaphylactoid reaction not described before with this drug.
authors.affiliation: Department of Allergy, Hospital Ramon y Cajal, Madrid, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Valdivieso
authors.forename: J
authors.initials: J
authors.lastname: Pola
authors.forename: E
authors.initials: E
authors.lastname: Losada
authors.forename: J
authors.initials: J
authors.lastname: Subiza
authors.forename: A
authors.initials: A
authors.lastname: Armentia
authors.forename: C
authors.initials: C
authors.lastname: Zapata
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009268:Nalidixic Acid / Q000009:adverse effects*; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D009268:Nalidixic Acid