Amikacin-acetyltransferase (AAC-6'/I) encoded by an IncH2 plasmid (pIE866) in Escherichia coli strains.
An amikacin resistance plasmid was detected in E. coli wild type strains isolated from polluted surface water. This conjugative 145 Md plasmid belongs to the IncH2 group and specifies amino-glycoside-acetyltransferase AAC-6'/I activity.
Voigt
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Institut für Experimentelle Epidemiologie, Wernigerode, DDR.
Tschäpe
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Heier
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D000123:Acetyltransferases / Q000235:genetics*; D000583:Amikacin / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D011815:R Factors; D013379:Substrate Specificity; D014871:Water Microbiology
D000900:Anti-Bacterial Agents; D000583:Amikacin; D000123:Acetyltransferases; C056532:aminoglycoside N(6')-acetyltransferase