title: Relationship between serum lipoproteins and hemostatic parameters in men with prostatic cancer.
abstract: Serum lipoprotein concentrations were related to hemostatic parameters in a group of 31 men before and during three different hormone treatment regimens for prostate cancer in an attempt to analyse to what extent the changes in these two systems correlate. In a correlation matrix the number of significant relationships at the 5% and 1% level corresponded to what could be expected by chance. The study thus failed to demonstrate any consistent relationship between any lipoprotein lipid concentration and the hemostatic parameters in men treated for prostate cancer. Most significant relationships were found for HDL-TG versus plasminogen, but the clinical significance of this observation is not clear.
authors.affiliation: Dept of Clinical Chemistry and Blood Coagulation, Karolinska Hospital, Stockholm, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Blombäck
authors.forename: P O
authors.initials: PO
authors.lastname: Hedlund
authors.forename: U
authors.initials: U
authors.lastname: Säwe
authors.forename: S
authors.initials: S
authors.lastname: Rössner
mesh_terms: D045166:Estradiol Congeners / Q000627:therapeutic use; D006487:Hemostasis; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D009919:Orchiectomy; D010958:Plasminogen / Q000378:metabolism; D011471:Prostatic Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D013997:Time Factors; D014280:Triglycerides / Q000097:blood; D014568:Urokinase-Type Plasminogen Activator / Q000037:antagonists & inhibitors
chemical_list: D045166:Estradiol Congeners; C034396:HDL-triglyceride; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D014280:Triglycerides; D010958:Plasminogen; D014568:Urokinase-Type Plasminogen Activator