title: Hypofractionated external radiation with high and low dose rates in the treatment of advanced cancer of the cervix.
abstract: Thirteen patients with cancer of the cervix Stage IIIb (heavy) were treated with high (9) and low (4) dose rates, once a week. A total dose of 4200 cGy was delivered over 7 weeks with a fraction size of 600 cGy. Six of nine patients showed complete response following high dose rate hypofractionated radiation. It is felt that synchronization of cells into a sensitive phase during low dose rate radiation is not the determinant of outcome even when duration of treatment is only 5 to 6 hours.
authors.affiliation: Division of Radiation Oncology, Dr. Balabhai Nanavati Hospital, Bombay, India.
authors.forename: N G
authors.initials: NG
authors.lastname: Huilgol
authors.forename: A R
authors.initials: AR
authors.lastname: Mehta
authors.forename: V
authors.initials: V
authors.lastname: Kulkarni
authors.forename: N
authors.initials: N
authors.lastname: Selvaraj
authors.forename: N
authors.initials: N
authors.lastname: Trivedi
mesh_terms: D005260:Female; D006801:Humans; D011446:Prospective Studies; D011879:Radiotherapy Dosage; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*