NMR studies of chromomycins, olivomycins, and their derivatives.
Detailed studies on the 13C and 1H NMR spectra of chromomycins A2 and A3, olivomycins A and B, and their derivatives clarified the assignment of many signals which had been unassigned or erroneously reported in the literatures. The revised assignments for chromomycin A3 and olivomycin A include the assignment of a key 13C signal used to discuss the saccharide linkage in question. Structure analyses based on the revised assignments support the alpha,1----3-bond between components of the disaccharide moiety in the molecules. Some general information useful for structure analysis of saccharides is also reported.
Yoshimura
Y
Y
Shionogi Research Laboratories, Shionogi & Co., Ltd., Osaka, Japan.
Koenuma
M
M
Matsumoto
K
K
Tori
K
K
Terui
Y
Y
D002865:Chromomycins / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D009848:Olivomycins / Q000302:isolation & purification* / Q000494:pharmacology
D002865:Chromomycins; D009848:Olivomycins; C055116:demethylolivomycin A; C055114:demethylchromomycin A2; C055117:demethylolivomycin B; C055115:demethylchromomycin A3