Multiple drug-resistance in Shigella flexneri isolated from a patient with human immunodeficiency virus.
Persistent shigellosis, due to Shigella flexneri resistant to multiple antibiotics, developed in a 40-yr-old homosexual man with human immunodeficiency virus infection. The Shigella strain demonstrated resistance to ampicillin, tetracycline, and trimethoprim-sulfamethoxazole. Although Shigella flexneri isolates resistant to trimethoprim-sulfamethoxazole are uncommon in the United States, laboratories should monitor resistance patterns through routine in vitro susceptibility testing.
Gander
R M
RM
Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston.
LaRocco
M T
MT
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004405:Dysentery, Bacillary / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D012763:Shigella flexneri / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents