title: Surgical therapy of localized abdominal non-Hodgkin's lymphomas.
abstract: Non-Hodgkin's lymphomas may involve a variety of abdominal organs, including the liver, spleen, gastrointestinal tract, and retroperitoneum. The number of organs potentially involved and the noncontiguous mode of spread make non-Hodgkin's lymphoma a difficult tumor to evaluate at the time of laparotomy. To clarify the surgical management of patients with this tumor, we retrospectively reviewed the medical records of 202 patients with histologically proven abdominal lymphomas. Within this group, 36 patients underwent laparotomy before they had chemotherapy or radiation therapy. Ten patients were explored to establish a histologic diagnosis of lymphoma. The remaining 26 patients underwent laparotomy because of presumed benign disease. Twenty patients were found to have localized disease at laparotomy. Patients with localized disease demonstrated significantly better survival than patients with extranodal and nodal involvement (p less than 0.05). Four patients with local resection received no adjuvant therapy and were free of disease a median of 50 months after surgery.
authors: Department of Surgery, Brigham and Women's Hospital, Boston, Mass.
authors: S J
authors: SJ
authors: Mentzer
authors: R T
authors: RT
authors: Osteen
authors: T N
authors: TN
authors: Pappas
authors: D S
authors: DS
authors: Rosenthal
authors: G P
authors: GP
authors: Canellos
authors: R E
authors: RE
authors: Wilson
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D013160:Splenic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery