A structural investigation of the capsular polysaccharide of Klebsiella K69.
The structure of the capsular polysaccharide isolated from Klebsiella serotype K69 has been investigated by a combination of chemical and spectroscopic methods. The repeating structure of the deacetylated polysaccharide is shown to be of the "3 + 1 + 1" type, and it carries a 1-carboxyethylidene acetal at positions 4 and 6 of a terminal galactosyl group. The location of acetyl groups in the polysaccharide has not been established. The repeating unit of the deacetylated polysaccharide has the following structure. (Formula: see text).
Hackland
P L
PL
School of Pharmaceutical Sciences, Rhodes University, Grahamstown, South Africa.
Parolis
H
H
Parolis
L A
LA
D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D007202:Indicators and Reagents; D007709:Klebsiella / Q000276:immunology*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008745:Methylation; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000032:analysis; D011135:Polysaccharides, Bacterial / Q000302:isolation & purification
D007202:Indicators and Reagents; D009844:Oligosaccharides; D011135:Polysaccharides, Bacterial