title: [Effect of choline on the DNA supramolecular complex in rats and their survival following gamma irradiation].
abstract: The injection of choline-chloride (200 mg/kg) to rats 15 min before 6 Gy irradiation was shown to increase their survival rate over a period of 30 days, to prolong their average life, and to promote the complete restoration of elastoviscosity of DNA supramolecular complexes in thymus, spleen, liver and brain. When administered immediately after irradiation the drug increased the survival rate of rats.
authors: N B
authors: NB
authors: Strazhevskaia
authors: V A
authors: VA
authors: Struchkov
mesh_terms: D000818:Animals; D002588:Cesium Radioisotopes; D002794:Choline / Q000627:therapeutic use*; D004247:DNA / Q000528:radiation effects*; D005720:Gamma Rays; D008297:Male; D011833:Radiation Injuries, Experimental / Q000235:genetics / Q000517:prevention & control*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D002588:Cesium Radioisotopes; D004247:DNA; D002794:Choline
vernacular_title: Deĭstvie kholina na nadmolekuliarnyĭ kompleks DNK krys i ikh vyzhivaemost' pri gamma-obluchenii.