Structure elucidation of two differentiation inducing factors (DIF-2 and DIF-3) from the cellular slime mould Dictyostelium discoideum.
Two endogenous differentiation-inducing factors (DIF-2 and DIF-3), which induce stalk-cell differentiation in the cellular slime mould Dictyostelium discoideum, have been identified as the pentan-1-one and monochloro analogues respectively of (1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one). These compounds represent a new chemical class of effector molecules.
Morris
H R
HR
Department of Biochemistry, Imperial College of Science and Technology, South Kensington, London, U.K.
Masento
M S
MS
Taylor
G W
GW
Jermyn
K A
KA
Kay
R R
RR
D002454:Cell Differentiation; D055598:Chemical Phenomena; D002621:Chemistry; D004023:Dictyostelium / Q000032:analysis*; D006588:Hexanones; D007659:Ketones; D013058:Mass Spectrometry
D006588:Hexanones; D007659:Ketones; C053433:1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone