Postanaesthetic arousal time in elderly patients. A double-blind study of glycopyrrolate and atropine.
Postanaesthetic arousal time was studied in elderly patients given either glycopyrrolate 0.01 mg kg-1 or atropine 0.02 mg kg-1 before antagonism of neuromuscular blockade. Forty patients (age greater than or equal to 65 yr) undergoing elective hip replacement were included in a double-blind study. Arousal was scored for 2 h after recovery using a modified scoring system. No difference in arousal time was found between the two groups.
Malling
B V
BV
Department of Anaesthesiology, Arhus University Hospital, Denmark.
Nissen
L R
LR
Larsen
K B
KB
Andersen
B N
BN
D000368:Aged; D000762:Anesthesia Recovery Period; D001143:Arousal / Q000187:drug effects*; D001285:Atropine / Q000494:pharmacology*; D004311:Double-Blind Method; D006024:Glycopyrrolate / Q000494:pharmacology*; D006801:Humans; D009388:Neostigmine / Q000494:pharmacology; D010197:Pancuronium / Q000037:antagonists & inhibitors; D011184:Postoperative Period; D011759:Pyrrolidines / Q000494:pharmacology*; D013997:Time Factors
D011759:Pyrrolidines; D009388:Neostigmine; D001285:Atropine; D010197:Pancuronium; D006024:Glycopyrrolate