title: Reduction of the nocturnal rise in pineal melatonin levels in rats exposed to 60-Hz electric fields in utero and for 23 days after birth.
abstract: Rats exposed to 60-Hz electric fields of either 10, 65, or 130 kV/m from conception to 23 days of age exhibited reduced peak nighttime pineal melatonin contents compared to unexposed controls. As a group, the exposed rats also exhibited a phase delay, estimated at approximately 1.4 hours, in the occurrence of the nocturnal melatonin peak. No clear dose-response relationship was noticed over the range of electric field strengths used as treatments in these experiments. These are the first studies concerned with the effects of electric field exposure on the pineal melatonin rhythm in immature rats. The findings are generally consistent with those obtained using adult rats, where electric field exposure has been shown to abolish the nighttime rhythm in pineal melatonin concentrations.
authors: Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284.
authors: R J
authors: RJ
authors: Reiter
authors: L E
authors: LE
authors: Anderson
authors: R L
authors: RL
authors: Buschbom
authors: B W
authors: BW
authors: Wilson
mesh_terms: D000818:Animals; D002940:Circadian Rhythm; D004560:Electricity; D005260:Female; D005333:Fetus / Q000502:physiology*; D008297:Male; D008550:Melatonin / Q000378:metabolism*; D010870:Pineal Gland / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D011247:Pregnancy; D051381:Rats
chemical_list: D008550:Melatonin