Red cell alloimmunization in chronic renal failure patients undergoing hemodialysis.
Posttransfusion alloimmunization to red cell antigens was studied in a group of 98 chronic renal disease patients treated solely with hemodialysis. Clinically significant red cell antibodies were formed in only 6.1% of transfused patients, and only 1 patient formed more than one antibody. We do not recommend extended red cell phenotyping, beyond ABO and Rh(D), in patients with end-stage renal disease who may require transfusion.
Domen
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Department of Pathology and Laboratory Medicine, University of South Florida College of Medicine, Tampa.
Ramirez
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis*; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D065227:Transfusion Reaction
D007518:Isoantibodies