The effect of sera from cats infected with Brugia pahangi and subsequently treated with levamisole on the infectivity of third-stage larvae of B. pahangi.
Cats were treated with levamisole and the infective (L3) stage of Brugia pahangi. Serum from infected cats was subsequently tested for its ability to infect jirds. Jirds autopsied at 33 days postmortem showed significant levels of parasitemia. This is contrary to reports of a previous study wherein serum from humans infected with B. malayi was found to induce cell adherence and death of the L3.
Denham
D A
DA
London School of Hygiene and Tropical Medicine, England.
Samad
R
R
D000818:Animals; D002009:Brugia / Q000276:immunology / Q000502:physiology*; D002415:Cats; D004605:Elephantiasis, Filarial / Q000188:drug therapy / Q000276:immunology / Q000469:parasitology*; D005368:Filariasis / Q000469:parasitology*; D005849:Gerbillinae / Q000469:parasitology*; D007814:Larva / Q000187:drug effects; D007978:Levamisole / Q000494:pharmacology* / Q000627:therapeutic use
D007978:Levamisole