Vasopressin and oxytocin neurohypophysial content under conditions of beta-adrenergic blockade in euhydrated and dehydrated rats: further studies.
Rats euhydrated and dehydrated for two days were given intracerebroventricularly (i.c.v.) propranolol hydrochloride in a daily dose of 10 micrograms. In euhydrated rats the single dose of propranolol diminished significantly the vasopressin and oxytocin content in the neurohypophysis. On the contrary, in animals dehydrated for two days the depletion of the vasopressin and oxytocin neurohypophysial storage was distinctly less marked during i.c.v. treatment with propranolol.
Janus
J
J
Department of Pathophysiology, University School of Medicine, Lôdź/Poland.
Guzek
J W
JW
D000818:Animals; D003681:Dehydration / Q000378:metabolism*; D007276:Injections, Intraventricular; D008297:Male; D010121:Oxytocin / Q000378:metabolism*; D010904:Pituitary Gland, Posterior / Q000187:drug effects / Q000378:metabolism*; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D014667:Vasopressins / Q000378:metabolism*
D014667:Vasopressins; D010121:Oxytocin; D011433:Propranolol