title: Bacterial adherence to endothelial cells from rat heart, with special regard to alpha-hemolytic streptococci.
abstract: Endothelial cells were prepared from rat heart, and the ability of various bacterial species to adhere to these cells was investigated, with special regard to alpha-hemolytic streptococci. The endothelial cells were identified by morphology and by the presence of F VIII antigen. Seventeen bacterial strains representing various species were used in the in vitro adherence tests; 10 strains represented various strains of alpha-hemolytic streptococci, 5 of which were isolated from patients with infective endocarditis and 5 from the throats of healthy individuals; 2 were Neisseria meningitidis, 2 N. gonorrhoeae, 2 S. aureus and 1 E. coli. The highest adherence rate was found for alpha-hemolytic streptococci isolated from patients with infective endocarditis. The difference compared to carrier strains of alpha-hemolytic streptococci and to the other tested strains was statistically highly significant.
authors: Department of Pediatrics, Orebro Medical Center Hospital, Sweden.
authors: J
authors: J
authors: Schollin
authors: D
authors: D
authors: Danielsson
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001422:Bacterial Adhesion; D002478:Cells, Cultured; D004697:Endocarditis, Bacterial / Q000382:microbiology*; D004727:Endothelium / Q000382:microbiology; D006321:Heart / Q000382:microbiology*; D006801:Humans; D010614:Pharynx / Q000382:microbiology; D051381:Rats; D011919:Rats, Inbred Strains; D018805:Sepsis / Q000382:microbiology; D013290:Streptococcal Infections / Q000382:microbiology*; D013291:Streptococcus / Q000502:physiology*