title: [Hypothalamic insufficiency following irradiation. Late, subacute and curable dementia].
abstract: A 31 year-old patient suffered from a subacute and major dementia, sixty months after whole brain irradiation with 54 grays for a pinealoma. Clinical features and biological investigations led to a diagnosis of hypothalamic insufficiency. A dramatic clinical recovery followed therapy with hydrocortisone and thyroxine. An hypothalamic radionecrosis and a vascular mechanism are presumed.
authors: Service de Neurologie, Hôpital Neurologique, Lyon.
authors: N
authors: N
authors: Nighoghossian
authors: C
authors: C
authors: Confavreux
authors: G
authors: G
authors: Sassolas
authors: D
authors: D
authors: Boisson
authors: A
authors: A
authors: Vighetto
authors: G
authors: G
authors: Aimard
authors: M
authors: M
authors: Trillet
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000532:radiotherapy*; D003704:Dementia / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007027:Hypothalamic Diseases / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D007031:Hypothalamus / Q000528:radiation effects*; D008297:Male; D010870:Pineal Gland
vernacular_title: Insuffisance hypothalamique après irradiation. Démence tardive, subaiguë et curable.