Skin permeation of chlorpheniramine maleate and detection of demethylated metabolites by high-performance liquid chromatography.
Zbaida
S
S
Hebrew University of Jerusalem, Israel.
Touitou
E
E
D000818:Animals; D001711:Biotransformation; D002744:Chlorpheniramine / Q000031:analogs & derivatives / Q000378:metabolism / Q000493:pharmacokinetics*; D002851:Chromatography, High Pressure Liquid; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008812:Mice, Hairless; D010539:Permeability; D012867:Skin / Q000378:metabolism*
C041905:N-desmethylchlorpheniramine; C041906:N,N-didemethylchlorpheniramine; D002744:Chlorpheniramine