Stability of isoniazid and acetylisoniazid in saliva.
The stability of isoniazid and acetylisoniazid in saliva was studied under various conditions. Acetylisoniazid was stable at 4 degrees, -20 degrees, and -70 degrees C for up to 5 weeks but isoniazid loss was prevented only by storage at -70 degrees C or by addition of azide and storage at 4 degrees C (but not -20 degrees C) for up to 5 weeks.
Hutchings
A
A
Department of Toxicology, Llandough Hospital, Penarth, S. Glam., U.K.
Spragg
B P
BP
Routledge
P A
PA
D004355:Drug Stability; D006801:Humans; D007538:Isoniazid / Q000031:analogs & derivatives* / Q000032:analysis*; D012463:Saliva / Q000032:analysis*; D013696:Temperature
C006377:(N)1-acetylisoniazid; D007538:Isoniazid