title: [Value of esogastroduodenal endoscopy with staged biopsies in children with Crohn's disease].
abstract: An upper gastrointestinal endoscopy with multiple biopsies was performed in 19 children suspected of Crohn disease (CD) who had also undergone X-ray investigations and colonoscopy with multiple biopsies. Biopsies were performed in pathological and/or normal mucous areas. Upper gastrointestinal endoscopy showed macroscopic changes in 7 children (37%). Histologic examinations of the upper gastrointestinal tract were normal or showed only non specific changes in 12 cases (63%). Histopathologic changes specific for CD were found in 7 cases (37%), while specific histologic changes were identified at the rectal or colic level in 3 of these 7 cases only. Thus, upper gastrointestinal endoscopy with multiple biopsies was most useful for the diagnosis of CD, since it was the only diagnostic means in 4 cases. It should be systematically performed when CD is suspected.
authors: Service de Gastro-entérologie et Nutrition pédiatrique, Hôpital Bretonneau, Paris.
authors: L M
authors: LM
authors: Mashako
authors: J F
authors: JF
authors: Mougenot
authors: E
authors: E
authors: Sonsino
authors: J P
authors: JP
authors: Cezard
authors: J L
authors: JL
authors: Charritat
authors: P
authors: P
authors: Foucaud
authors: J
authors: J
authors: Navarro
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D002648:Child; D003424:Crohn Disease / Q000473:pathology*; D004378:Duodenal Diseases / Q000473:pathology; D004384:Duodenoscopy; D004935:Esophageal Diseases / Q000473:pathology; D004945:Esophagoscopy; D005069:Evaluation Studies as Topic; D005260:Female; D005336:Fiber Optic Technology; D005773:Gastroscopy; D006801:Humans; D008297:Male; D013272:Stomach Diseases / Q000473:pathology
vernacular_title: Intérêt de l'endoscopie oeso-gastro-duodénale avec biopsies étagées chez des enfants suspects de maladie de Crohn.