Generation and characterization of cyclosporine metabolites produced in a hepatic microsomal system.
Cheung
F
F
Department of Medicine, University of Toronto, Ontario, Canada.
Wong
P Y
PY
Cole
E
E
Cohen
Z
Z
Levy
G A
GA
D000818:Animals; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D003208:Concanavalin A / Q000494:pharmacology; D003524:Cyclosporins / Q000378:metabolism* / Q000494:pharmacology; D007165:Immunosuppression Therapy; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects; D008862:Microsomes, Liver / Q000378:metabolism*; D011817:Rabbits; D011863:Radioimmunoassay; D051381:Rats; D013329:Structure-Activity Relationship
D003524:Cyclosporins; D003208:Concanavalin A