Accumulation of ornithine by chick retinal pigment epithelium cells in culture.
This study was designed to measure the accumulation of ornithine in retinal pigment epithelium cells grown in culture. Ornithine accumulated in retinal pigment epithelium cells in which the ornithine aminotransferase activity was inhibited with L-canaline. The effect of L-canaline was eliminated by the concomitant presence of methionine.
Baich
A
A
Biology Department, Southern Illinois University, Edwardsville 62026.
Nekola
M
M
D000613:Aminobutyrates / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D008715:Methionine / Q000494:pharmacology; D009952:Ornithine / Q000378:metabolism*; D009953:Ornithine-Oxo-Acid Transaminase / Q000378:metabolism; D010857:Pigment Epithelium of Eye / Q000378:metabolism*; D011730:Pyridoxal / Q000494:pharmacology
D000613:Aminobutyrates; D011730:Pyridoxal; C001926:canaline; D008715:Methionine; D009952:Ornithine; D009953:Ornithine-Oxo-Acid Transaminase