title: Intravenous natural beta interferon treatment of chronic exacerbating-remitting multiple sclerosis: clinical response and MRI/CSF findings.
abstract: A preliminary study is reported of clinical response and CSF/MRI findings in nine patients with multiple sclerosis receiving intravenous infusions of natural beta-interferon. The mean patient follow-up was for 1.2 years. Neither exacerbation rates nor CSF-IgG synthesis nor plaque formation as revealed by MRI showed a significant reduction during therapy. One patient developed a severe exacerbation of multiple sclerosis shortly after interferon infusion.
authors: Universitäts-Nervenklinik Köln, Schwerpunkt Neurologie, Federal Republic of Germany.
authors: M
authors: M
authors: Huber
authors: S
authors: S
authors: Bamborschke
authors: J
authors: J
authors: Assheuer
authors: W D
authors: WD
authors: Heiss
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007370:Interferon Type I / Q000008:administration & dosage*; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000628:therapy*
chemical_list: D007370:Interferon Type I