title: Isolation and characterization of growth hormone from blue fox pituitary glands.
abstract: Growth hormone has been purified to homogeneity from blue fox pituitary glands. It has 191 amino acids with two disulfide bridges and a single tryptophan residue. The somatotropin activity is only 8% when compared with the bovine hormone in the receptor-binding assay. From radioimmunoassay data using baboon antisera to porcine or bovine growth hormone, the fox hormone has 14-17% immunoreactivity of bovine or porcine hormone.
authors: Laboratory of Molecular Endocrinology, University of California, San Francisco.
authors: C H
authors: CH
authors: Li
authors: D
authors: D
authors: Chung
authors: J
authors: J
authors: Izdebski
authors: T
authors: T
authors: Majewski
authors: T F
authors: TF
authors: Mowles
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000378:metabolism; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D004220:Disulfides / Q000032:analysis; D005589:Foxes / Q000502:physiology*; D013006:Growth Hormone / Q000302:isolation & purification* / Q000378:metabolism; D007106:Immune Sera; D008099:Liver / Q000378:metabolism; D008969:Molecular Sequence Data; D010215:Papio; D010902:Pituitary Gland / Q000032:analysis*; D011817:Rabbits; D011863:Radioimmunoassay; D011986:Receptors, Somatotropin / Q000378:metabolism; D014364:Tryptophan
chemical_list: D004220:Disulfides; D007106:Immune Sera; D011986:Receptors, Somatotropin; D014364:Tryptophan; D013006:Growth Hormone