Spontaneous alternation and exploration in staggerer mutant mice.
Staggerer mutant mice were found to be less active in terms of motor activity in a maze, hole poking and rearing. Staggerer mutant mice also showed a lack of spontaneous alternation in both 2-trial and 4-trial tests. A lack of spontaneous alternation in this mutant may be due to a deficit in response inhibition or in spatial orientation, similar to that of animals with limbic lesions.
Lalonde
R
R
Service of Neurology, Hôtel-Dieu Hospital, University of Montreal, Canada.
Manseau
M
M
Botez
M I
MI
D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D007266:Inhibition, Psychological / Q000502:physiology; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000502:physiology*; D009043:Motor Activity / Q000502:physiology*; D013028:Space Perception / Q000502:physiology