[Resectability of primary carcinoma of the liver and pancreas, with special reference to radicality and functional reserve].
Resectability was studied in relation to both the functional reserve of the liver or pancreas and radicality in 112 cases of primary liver cancer and 34 cases of pancreatic head cancer resected in our department over an 11-year period. 1. Primary liver cancer: In extended hepatectomy including one segment beyond the tumor-bearing area, recurrence rate was low with a high long-term survival rate of more than 3 years, although hepatic insufficiency occurred frequently. In limited resection of the segment of the tumor or enucleation, many patients died due to recurrence within 2 years, except for those with small liver cancers. 2. Pancreatic head cancer: Extended surgery especially total pancreatectomy, had higher radicality with a higher 3-year survival rate than for the standard operation, even in case of advanced stage III or IV cancer. However, extended surgery produced a high incidence of postoperative fatty liver due to disturbance of pancreatic exo- and endocrine function, and severe diarrhea following dissection of the nerve plexus. Therefore, it is necessary to select a suitable operative method upon consideration of both radicality and functional reserve of the liver or the pancreas.
Noguchi
T
T
1st Dept. of Surgery, Mie University School of Medicine.
Kita
T
T
Mizumoto
R
R
D006498:Hepatectomy / Q000401:mortality* / Q000534:rehabilitation; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D010180:Pancreatectomy / Q000401:mortality* / Q000534:rehabilitation; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D011379:Prognosis; D011788:Quality of Life