Myosin heavy chain composition of single fibres from normal human muscle.
Electrophoretic analysis in the presence of 33% glycerol of purified myosin from normal human muscle shows three distinct protein bands which are identified as type 1, 2B, and 2A myosin heavy chain (MHC) isoforms by affinity-purified polyclonal antibodies. Analysis of MHC of single human muscle fibres shows that human muscles contain a large population of fibres showing the coexistence of type 2A and 2B MHC.
Biral
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D
Centro del C.N.R. per lo Studio della Biologia e Fisiopatologia Muscolare, Università di Padova, Italy.
Betto
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R
Danieli-Betto
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D
Salviati
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G
D000328:Adult; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007122:Immunoelectrophoresis; D009132:Muscles / Q000032:analysis*; D009218:Myosins / Q000032:analysis*
D009218:Myosins