title: Presence of calcium oxalate crystals in the mammalian thyroid gland.
abstract: Birefringent crystals of calcium oxalate have been previously identified in the colloid of human thyroid glands. We found such crystals in 19/20 adult thyroids at autopsy, in 4/20 infants at autopsy, and, using frozen sections, in 19/20 thyroids partially or totally removed at surgery. These crystals were soluble in hydrochloric acid, insoluble in acetic acid, and contained only calcium by energy dispersive X-ray microanalysis, confirming their calcium oxalate character. Similar crystals were found in equine and ovine thyroids.
authors: Department of Pathology, College of Medicine, University of Florida, Gainesville.
authors: R L
authors: RL
authors: Hackett
authors: S R
authors: SR
authors: Khan
mesh_terms: D001718:Birefringence; D002129:Calcium Oxalate / Q000032:analysis*; D004577:Electron Probe Microanalysis; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013959:Thyroid Diseases / Q000473:pathology; D013961:Thyroid Gland / Q000002:abnormalities / Q000473:pathology / Q000648:ultrastructure*; D013964:Thyroid Neoplasms / Q000473:pathology
chemical_list: D002129:Calcium Oxalate