The conundrum of relaxation times.
The current theories of proton relaxation times fall short of explaining satisfactorily the physical and biological mechanisms responsible for the dissimilarities of relaxation behavior in normal and pathological tissues. An alternative approach to understand these mechanisms is needed. This paper advances the possibility that the dissimilarities of relaxation behavior in normal and pathological tissues is due to the consumption of paramagnetic molecular O2 dissolved in cell-associated water.
Akber
S F
SF
Department of Biomedical Engineering, Worcester Polytechnic Institute, MA.
D001834:Body Water / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009369:Neoplasms / Q000473:pathology*; D010101:Oxygen Consumption