Influence of 60-Hertz magnetic fields on leukemia.
Female DBA/2 mice at 8 weeks of age were implanted with P388 leukemia cells in groups of ten mice and exposed to a 60-Hz 1.4-microT, 200-microT, or 500-microT magnetic field 2-3 hours after the implant for 6 hours daily, 5 days/week until all the exposed P388-treated and nontreated mice died. Parallel exposed groups of non-P388-treated mice and P388-treated mice exposed at 0 microT were included for study. No statistically significant differences (P greater than .05) in survival, spleen weight, or body weight resulted between P388-treated or nontreated mice from exposure to the magnetic field. No effect on the incidence or progression of P388 leukemia was apparent.
Thomson
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University of Rochester Nonionizing Radiant Energy Facility, Department of Biophysics, School of Medicine and Dentistry, New York 14642.
Michaelson
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Nguyen
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D000818:Animals; D001835:Body Weight / Q000528:radiation effects; D004574:Electromagnetic Fields / Q000009:adverse effects*; D055590:Electromagnetic Phenomena / Q000009:adverse effects*; D005260:Female; D007941:Leukemia P388 / Q000209:etiology* / Q000473:pathology; D007942:Leukemia, Experimental / Q000209:etiology*; D007953:Leukemia, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D051379:Mice; D008811:Mice, Inbred DBA; D009929:Organ Size / Q000528:radiation effects; D013154:Spleen / Q000473:pathology / Q000528:radiation effects