title: [Metabolic products of methandrostenolone in the body of white rats studied by high-performance liquid chromatography].
abstract: Metabolism of the anabolic steroidal hormone methandrostenolone in Wistar rats was studied by high performance liquid chromatography (HPLC) and redioisotope techniques. The conditions for isolation of methandrostenolone metabolites by HPLC were developed. Reduction of the double bonds was shown to be an early stage in methandrostenolone biotransformation. The main portion of the metabolites was excreted with urine as glucuronide conjugates. No sulfoesters were found.
authors: Iu F
authors: IuF
authors: Krylov
authors: E Iu
authors: EIu
authors: Krynetskiĭ
authors: B S
authors: BS
authors: Prokhorov
authors: G A
authors: GA
authors: Sapozhnikova
authors: P A
authors: PA
authors: Smirnov
mesh_terms: D000818:Animals; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005243:Feces / Q000032:analysis; D008099:Liver / Q000032:analysis / Q000378:metabolism; D008297:Male; D008696:Methandrostenolone / Q000032:analysis / Q000493:pharmacokinetics*; D051381:Rats; D011919:Rats, Inbred Strains; D014316:Tritium
chemical_list: D014316:Tritium; D008696:Methandrostenolone
vernacular_title: Izuchenie produktov metabolizma metandrostenolona v organizme belykh krys metodom vysokoéffektivnoĭ zhidkostnoĭ khromatografii.