Enhancement of phagocytic activity of human monocytic-macrophagic cells by immunostimulating peptides from human casein.
Two immunostimulating peptides, Val-Glu-Pro-Ile-Pro-Tyr and Gly-Leu-Phe, obtained from human caseins, were demonstrated to significantly stimulate binding of human senescent red blood cells to human monocytic-macrophagic cells and their phagocytosis by these cells.
Gattegno
L
L
Laboratoire de Biologie Cellulaire Médicale, Université Paris XIII, Faculté de Médecine, Bobigny, France.
Migliore-Samour
D
D
Saffar
L
L
Jollès
P
P
D000276:Adjuvants, Immunologic / Q000302:isolation & purification* / Q000494:pharmacology; D002364:Caseins / Q000032:analysis*; D004912:Erythrocytes; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000187:drug effects* / Q000502:physiology; D008264:Macrophages / Q000187:drug effects* / Q000502:physiology; D010455:Peptides / Q000302:isolation & purification* / Q000494:pharmacology; D010587:Phagocytosis / Q000187:drug effects*
D000276:Adjuvants, Immunologic; D002364:Caseins; D010455:Peptides