Aerocyanidin, a new antibiotic produced by Chromobacterium violaceum.
Aerocyanidin, a new antibiotic containing an isonitrile group, has been isolated from fermentations of Chromobacterium violaceum ATCC 53434. Structure 1 was assigned on the bais of spectroscopic characterization of the antibiotic and of a degradation product that results from treatment with base. The antibiotic is primarily active against Gram-positive bacteria.
Parker
W L
WL
Squibb Institute for Medical Research, Princeton, New Jersey 08543-4000.
Rathnum
M L
ML
Johnson
J H
JH
Wells
J S
JS
Principe
P A
PA
Sykes
R B
RB
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D002861:Chromobacterium / Q000378:metabolism*; D005285:Fermentation; D008968:Molecular Conformation; D009570:Nitriles / Q000302:isolation & purification / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D009570:Nitriles; C056027:aerocyanidin