title: Reference values for pulsed Doppler signals from the blood flow velocity on both sides of the pulmonary valve.
abstract: Pulsed Doppler signals were recorded from the pulmonary artery and the right ventricular outflow tract in 215 healthy subjects (120 males, 95 females; 1-65 years). Amplitude spectra from these Doppler signals were stored in digital form together with adjustment data for the instrument and the simultaneously recorded ECG. From these Doppler spectra the median of the maximal velocity (Vmax), the maximal acceleration (Amax) and the dispersion of the velocity distribution around Vmax (width) were calculated. These three median values were used to characterize the Doppler spectra and to define normal values for bloodflow velocities. Thus, calculations were made without observer interacting using a well-defined computer program. The effect of age, gender, body surface area and heart rate were studied. Reference ranges were calculated. There is a slight decrease of the median value of Vmax and Amax in the pulmonary artery during lifetime from 80 to 70 cm s-1 and from 1,200 to 800 cm s-2, respectively. On the other hand, there is no correlation between age and Vmax and Amax in the right ventricular outflow tract. The width of the spectra increases with age at both sites. No significant changes with age were seen with the other variables.
authors: Interuniversity Cardiology Institute, Radboud University Hospital, Nijmegen, The Netherlands.
authors: A
authors: A
authors: van Oort
authors: S
authors: S
authors: de Knecht
authors: I
authors: I
authors: van Dam
authors: A
authors: A
authors: Heringa
authors: T
authors: T
authors: de Boo
authors: J
authors: J
authors: Alsters
authors: J
authors: J
authors: Hopman
authors: J
authors: J
authors: Fast
authors: T
authors: T
authors: van der Werf
authors: O
authors: O
authors: Daniels
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D002648:Child; D002675:Child, Preschool; D003201:Computers; D004301:Doppler Effect; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D011664:Pulmonary Valve / Q000502:physiology*; D012016:Reference Values