title: Gas chromatography/mass spectrometry and gas chromatography/mass spectrometry/mass spectrometry of methyl ester/methoxime/trimethylsilyl ether derivatives of thromboxanes.
abstract: Electron impact mass spectra of methyl ester/methoxime/trimethylsilyl ether derivatives of thromboxane B2 (TxB2) and 2,3-dinor-TxB2 and methyl ester/trimethylsilyl ether derivative of 11-dehydro-TxB2 are presented. Additionally, the derivatives of (2H4)-thromboxanes and methyl ester (2H3)-methoxime/trimethylsilyl ether derivatives of TxB2 and 2,3-dinor-TxB2 and (2H3)-methyl ester/trimethylsilyl ether derivative of 11-dehydro-TxB2 were investigated. Collision-induced dissociation mass spectra of the most intense parent ion in the high-mass region were taken. Collisionally activated decomposition mass spectra of the [C(12)-C(20)]+ ion of TxB2 and 2,3-dinor-TxB2 show an intense but not specific daughter ion, whereas the collision-induced dissociation mass spectrum of the [M-(C(16)-C(20)]+ ion of 11-dehydro-TxB2 results in the formation of numerous daughter ions.
authors: Universitätskinderklinik, Heidelberg, FRG.
authors: H
authors: H
authors: Schweer
authors: H W
authors: HW
authors: Seyberth
authors: C O
authors: CO
authors: Meese
authors: O
authors: O
authors: Fürst
mesh_terms: D004952:Esters; D004987:Ethers; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D007202:Indicators and Reagents; D013931:Thromboxanes / Q000032:analysis*
chemical_list: D004952:Esters; D004987:Ethers; D007202:Indicators and Reagents; D013931:Thromboxanes