Nmr studies of colchicine and its photoisomers, beta- and gamma-lumicolchicines.
Unambiguous 1H- and 13C-nmr assignments of colchicine, beta-lumicolchicine, and gamma-lumicolchicine have been obtained using a combination of 1D- and 2D-nmr spectroscopic techniques. The data indicate that gamma-lumicolchicine is a stereoisomer of beta-lumicolchicine and provide definitive evidence for their stereochemical assignments.
Meksuriyen
D
D
Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago 60612.
Lin
L J
LJ
Cordell
G A
GA
Mukhopadhyay
S
S
Banerjee
S K
SK
D003078:Colchicine / Q000031:analogs & derivatives* / Q000032:analysis* / Q000528:radiation effects; D008162:Lumicolchicines / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D010777:Photochemistry; D014466:Ultraviolet Rays
D008162:Lumicolchicines; D003078:Colchicine