title: Distal vacuolar myopathy with complete heart block.
abstract: We describe a 26-year-old man with a predominantly distal myopathy and complete heart block. A muscle biopsy specimen demonstrated numerous vacuoles, which, by electron microscopy, contained membranous whorls. Filamentous inclusions characteristic of inclusion body myositis were not seen. It is important to be aware that life-threatening cardiac disease may occur in this setting.
authors: Department of Internal Medicine, Division of Neurology, Duke University Medical Center, Durham, NC.
authors: D A
authors: DA
authors: Krendel
authors: J M
authors: JM
authors: Gilchrist
authors: E H
authors: EH
authors: Bossen
mesh_terms: D000328:Adult; D006327:Heart Block / Q000150:complications*; D006801:Humans; D008297:Male; D009135:Muscular Diseases / Q000150:complications* / Q000473:pathology; D014617:Vacuoles / Q000473:pathology