Hypertension complicating essential thrombocythemia.
Essential thrombocythemia (ET) is a myeloproliferative disorder characterized by marked thrombocytosis with associated hemorrhagic, thrombotic and embolic complications caused by platelet dysfunction. In this report we describe two cases of ET and moderate to severe hypertension associated with renal artery stenosis and renal microvascular lesions. In both cases treatment of the hematologic disorder resulted in reduction of blood pressure and improvement of clinical symptoms.
Bruch
J S
JS
Department of Medicine, Vanderbilt University School of Medicine, Nashville.
Stein
R S
RS
Oates
J A
JA
D000328:Adult; D005260:Female; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D007668:Kidney / Q000473:pathology; D008297:Male; D012077:Renal Artery / Q000473:pathology; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000175:diagnosis / Q000473:pathology