Vaccination of mice with liposome-entrapped adult antigens of Nippostrongylus brasiliensis.
An immunization procedure was developed to induce protection of mice against the gastrointestinal helminth Nippostrongylus brasiliensis. Mice immunized by the oral route with antigens which were released by adult worms during their in vitro survival in a detergent-containing medium and which were entrapped in liposomes were protected against a challenge infection.
Rhalem
A
A
Station de Recherches de Virologie et d'Immunologie, INRA, Thiverval-Grignon, France.
Bourdieu
C
C
Luffau
G
G
Pery
P
P
D000818:Animals; D000947:Antigens, Helminth / Q000008:administration & dosage* / Q000276:immunology; D008081:Liposomes / Q000008:administration & dosage*; D008213:Lymphocyte Activation; D051379:Mice; D008807:Mice, Inbred BALB C; D009559:Nippostrongylus / Q000276:immunology*; D051381:Rats; D014611:Vaccination
D000947:Antigens, Helminth; D008081:Liposomes