Cytogenetic effects of Cuman L, a dithiocarbamate fungicide.
Cuman L, a dithiocarbamate fungicide, was assessed for its effects in the germ cells and the bone marrow erythrocytes of Swiss Albino male mice. The 3 sublethal doses of 350, 700 and 1050 mg/kg b.w. of Cuman L induced a significant (P less than 0.01) increase in the number of chromosomal aberrations in the germ cells. A significant increase (P less than 0.01) in the percentage of micronuclei in the erythrocytes was also induced by the three doses.
Hemavathy
K C
KC
Department of Postgraduate Studies and Research in Zoology, University of Mysore, India.
Krishnamurthy
N B
NB
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects* / Q000648:ultrastructure; D002869:Chromosome Aberrations; D004912:Erythrocytes / Q000187:drug effects / Q000648:ultrastructure; D006412:Hematopoietic Stem Cells / Q000187:drug effects* / Q000648:ultrastructure; D008297:Male; D051379:Mice; D009153:Mutagens / Q000633:toxicity*; D013093:Spermatogonia / Q000187:drug effects* / Q000648:ultrastructure; D013094:Spermatozoa / Q000187:drug effects*; D013859:Thiocarbamates / Q000633:toxicity*; D015039:Ziram / Q000633:toxicity*
D009153:Mutagens; D013859:Thiocarbamates; D015039:Ziram