[Total synthesis and properties of prostaglandins. XIV. Amide derivatives of 3alpha-tetrahydrofuranyloxy-5-hydroxyimino-2beta- (3alpha-tetrahydrofuranyloxy-trans-1-octenyl)-cyclopentane- 1alpha-acetic acid].
Several novel prostaglandins containing an amide group in the alpha-chain have been prepared by the mixed carbonic anhydride method from 3 alpha-tetrahydrofuranyloxy-5-hydroxyimino-2 beta-(3 alpha- tetrahydrofuranyloxy-trans-1-octenyl)-cyclopentane-1 alpha-acetic acid and omega-amino acids with a linear chain of varying length (CH2-group number from 1 to 7). The physico-chemical properties of the title compounds were studied.
Kudriashova
V V
VV
Dikovskaia
K I
KI
Kalnin'sh
A P
AP
Kropivets
L S
LS
Freĭmanis
Ia F
IaF
D000577:Amides / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D003517:Cyclopentanes / Q000032:analysis / Q000138:chemical synthesis*; D005663:Furans / Q000032:analysis / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D011453:Prostaglandins / Q000032:analysis / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared
D000577:Amides; D003517:Cyclopentanes; D005663:Furans; D011453:Prostaglandins; C056253:3-tetrahydrofuranyloxy-5-hydroxyimino-2-(3-tetrahydrofuranyloxy-1-octenyl)cyclopentane-1-acetic acid
Total'nyĭ sintez i svoĭstva prostaglandinov. XIV. Amidnye proizvodnye 3alpha-tetragidrofuraniloksi-5-gidroksiimino-2beta- (3alpha-tetragidrofuraniloksi-trans-1-oktenil)-tsiklopentan- 1alpha-uksusnoĭ kisloty.