title: Cardiovascular and respiratory effects of oral premedication with trimeprazine and droperidol in children.
abstract: The systolic blood pressure, pulse rate and respiratory rate were assessed in 112 children before and after receiving premedication consisting of trimeprazine (3 mg/kg) and droperidol (0.2 mg/kg) by mouth. A mild (10%) drop in blood pressure was shown, but no statistical difference was found in the other parameters measured. The premedication is highly efficacious, 70% of patients being asleep in the preanaesthetic room; 27% were calm and only 3% were distressed or crying.
authors: Department of Anaesthesia, University of Cape Town.
authors: A D
authors: AD
authors: Butt
authors: B
authors: B
authors: Mets
mesh_terms: D000284:Administration, Oral; D001794:Blood Pressure / Q000187:drug effects*; D002648:Child; D002675:Child, Preschool; D004329:Droperidol / Q000008:administration & dosage / Q000494:pharmacology*; D004359:Drug Therapy, Combination; D006801:Humans; D007223:Infant; D011292:Premedication; D011446:Prospective Studies; D011674:Pulse / Q000187:drug effects*; D012119:Respiration / Q000187:drug effects*; D014291:Trimeprazine / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D014291:Trimeprazine; D004329:Droperidol