title: The early results from a randomised study of radiotherapy versus Nolvadex (tamoxifen) as initial treatment for stage III breast cancer.
abstract: Eighty-seven postmenopausal patients have been randomised to receive either radiotherapy or Nolvadex (tamoxifen) as first line treatment for locally advanced (stage III) breast cancer. After a median follow-up of two years no significant differences have been found in the rate of progression of local disease, the time to development of overt metastases or survival.
authors: City Hospital, Nottingham, U.K.
authors: M R
authors: MR
authors: Williams
authors: D
authors: D
authors: Gilson
authors: L
authors: L
authors: Marsh
authors: D A
authors: DA
authors: Morgan
authors: R I
authors: RI
authors: Nicholson
authors: C W
authors: CW
authors: Elston
authors: K
authors: K
authors: Griffiths
authors: R W
authors: RW
authors: Blamey
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011897:Random Allocation; D011960:Receptors, Estrogen / Q000032:analysis; D013629:Tamoxifen / Q000627:therapeutic use*; D014456:Ulcer / Q000209:etiology
chemical_list: D011960:Receptors, Estrogen; D013629:Tamoxifen