Familial imprinting determines H-2 selective mating preferences.
Inbred male mice typically prefer to mate with females of a different, non-self H-2 haplotype. To determine whether this natural preference is irrevocable or results from familial imprinting, a test system was used which relied on previous observations that B6 males (H-2b) mate preferentially with congenic B6-H-2k rather than B6 females, and B6-H-2k males with B6 females. This preference was reversed in B6 males fostered by B6-H-2k parents and in B6-H-2k males fostered by B6 parents, preference in these cases favoring the same H-2 type. Thus, H-2 selective mating preference is acquired by imprinting on familial H-2 types.
Yamazaki
K
K
Monell Chemical Senses Center, Philadelphia, PA 19104.
Beauchamp
G K
GK
Kupniewski
D
D
Bard
J
J
Thomas
L
L
Boyse
E A
EA
D000818:Animals; D005260:Female; D006183:H-2 Antigens / Q000235:genetics*; D007173:Imprinting, Psychological; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D009812:Odorants; D012726:Sexual Behavior, Animal; D012903:Smell / Q000502:physiology
D006183:H-2 Antigens