title: Nature of mononuclear cells positive for acid phosphatase activity in bone marrow of patients with renal osteodystrophy.
abstract: Fifty two of 63 patients with renal osteodystrophy had one or more mononuclear cells positive for acid phosphatase in the marrow. These cells are also tartrate resistant and non-specific esterase negative, and are believed to be precursors to osteoclasts and other acid phosphatase positive cells resorbing bone on the trabecular surface.
authors: Division of Nephrology, Montreal General Hospital, Quebec, Canada.
authors: M
authors: M
authors: Kaye
authors: J
authors: J
authors: Henderson
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D001853:Bone Marrow / Q000201:enzymology*; D001862:Bone Resorption / Q000201:enzymology; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000201:enzymology*; D006801:Humans; D010010:Osteoclasts / Q000187:drug effects / Q000201:enzymology*; D010281:Parathyroid Hormone / Q000378:metabolism; D013644:Tartrates / Q000494:pharmacology
chemical_list: D010281:Parathyroid Hormone; D013644:Tartrates; D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase; D000135:Acid Phosphatase; C029768:tartaric acid