title: Skeletal scintigraphy and physical examination in the staging of early breast cancer.
abstract: The significance of skeletal scintigraphy in staging of early breast cancer is still controversial. The results of bone scanning with 99Tcm diphosphonate and clinical examination in 204 patients with stage I-II breast cancer are reported. Bone scans were positive in 28 cases. However, only one was true positive as confirmed by x-ray examination and/or biopsy, with a detection rate of 0.5%. Physical examination had a detection rate similar to bone scan, but with superior specificity. In our experience bone scan cannot be recommended as a routine staging test in early breast cancer.
authors: Department of Oncology and Radiation Therapy, Istituti Ospedalieri S. Chiara, Trento, Italy.
authors: S
authors: S
authors: Piffer
authors: M
authors: M
authors: Amichetti
authors: A
authors: A
authors: Valentini
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011182:Postoperative Care; D011300:Preoperative Care; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate