Treatment of diabetic neuropathy with pentoxifylline: case report.
Diabetic neuropathy includes a heterogenous group of neuropathic syndromes associated with diabetes mellitus. One form of diabetic neuropathy is distal symmetric polyneuropathy, which is characterized at a late stage by intractable pain. This pain is generally refractory to present modalities of therapy except for narcotics. Pentoxifylline offers a new approach to therapy, reducing the blood viscosity and improving perfusion of ischemic microcirculation. A case report will be presented of intractable painful peripheral neuropathy responding dramatically to pentoxifylline therapy.
Kalmansohn
R B
RB
UCLA Medical Center.
Kalmansohn
R W
RW
Markham
C H
CH
Schiff
D L
DL
D000368:Aged; D000369:Aged, 80 and over; D003929:Diabetic Neuropathies / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D010148:Intractable Pain / Q000188:drug therapy / Q000209:etiology; D010431:Pentoxifylline / Q000627:therapeutic use*; D013805:Theobromine / Q000031:analogs & derivatives*
D013805:Theobromine; D010431:Pentoxifylline