title: Bilateral abductor paresis masquerading as asthma.
abstract: Rare upper airway lesions may be mistaken for asthma. A 16-year-old Hispanic male athlete presented to our allergy clinic with a 4-month history of wheezing and snoring with hoarseness and progressive fatigue on exertion or during sleep. His mother taped periods of harsh stridor and sleep apnea. There was no family history of vocal cord abnormalities. A year before the onset of symptoms, he suffered injury to his oral cavity with a loss of consciousness during a wrestling match. He denied dysphagia or dysphonia. He failed to respond to bronchodilators, cromolyn, or prednisone therapy during 4 weeks. On referral to our clinic, his physical examination and tape recording were characterized by harsh inspiratory stridor. His pulmonary function tests were significant for peak flow depressed out of proportion to FEV1 with reduced FVC, no response to bronchodilator, and flattened inspiratory loop unresponsive to cough or panting. Fluoroscopy and endoscopy of the upper airway was consistent with "marked bilateral limitation of vocal cord abduction." Sleep study demonstrated desaturation with CO2s in the 60s during sleep. He was started on continuous positive airway pressure, 10 cm at night, with no desaturation or sleep disturbance on follow-up.
authors: Pediatric Pulmonary Unit, Massachusetts General Hospital, Boston.
authors: C
authors: C
authors: Randolph
authors: A
authors: A
authors: Lapey
authors: D C
authors: DC
authors: Shannon
mesh_terms: D000293:Adolescent; D000402:Airway Obstruction / Q000209:etiology; D001249:Asthma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D007821:Laryngeal Muscles / Q000503:physiopathology*; D008297:Male; D009132:Muscles / Q000503:physiopathology*; D012135:Respiratory Sounds / Q000209:etiology; D014826:Vocal Cord Paralysis / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology