Reflectance spectrophotometry, cerebral blood flow and congestion in young rabbit brain.
Reflectance spectrophotometry was applied to examine experimental cerebral oxygenation and hemodynamics in young rabbits. The estimated brain tissue SO2 level (ISO2) showed a prompt response to acute hypoxemia. The estimated brain tissue hemoglobin concentration (IHb) showed good correlation with CBF changes, estimated by the H2 clearance method, on hypoxemia or hypercarbia, and with cerebral congestion on neck venous compression. Moreover, trend recording of IHb and ISO2 was useful for monitoring the cerebral oxygenation and hemodynamic changes, including CBF as well as congestion.
Takashima
S
S
Division of Mental Retardation and Birth Defect, National Institute of Neuroscience, Tokyo, Japan.
Ando
Y
Y
D000818:Animals; D001927:Brain Diseases / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D010101:Oxygen Consumption; D011817:Rabbits; D013054:Spectrophotometry, Atomic
D006454:Hemoglobins