Eosinophilic histiocytosis. A subset of lymphomatoid papulosis.
A 43-year-old male with a 23-year history of small-plaque-type parapsoriasis developed a chronic recurrent self-healing papulonodular and tumoral cutaneous eruption. The microscopic findings were consistent with eosinophilic histiocytosis. Immunohistochemical and ultrastructural studies revealed a population of T lymphocytes, eosinophils and monocyte-macrophage cells in the dermal infiltrate. These findings confirm the similarities between eosinophilic histiocytosis and lymphomatoid papulosis suggesting that the former may be a clinicopathologic variant of the latter.
Tuneu
A
A
Department of Dermatology, Hospital de Sant Pau, Barcelona, Spain.
Moreno
A
A
Pujol
R M
RM
de Moragas
J M
JM
D000328:Adult; D002908:Chronic Disease; D004804:Eosinophils / Q000648:ultrastructure*; D006644:Histiocytes / Q000648:ultrastructure*; D006801:Humans; D007150:Immunohistochemistry; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D010267:Parapsoriasis / Q000378:metabolism / Q000473:pathology*; D012008:Recurrence; D012878:Skin Neoplasms / Q000032:analysis / Q000648:ultrastructure*