title: [Determinants of local tumor control in interstitial radiotherapy of prostatic cancer].
abstract: Clinical followup of 52 patients treated with I-125 implants for localized prostatic cancer demonstrated local control in 85% and failure in 15%. Determining factors for local control or failure were analyzed and underline that homogeneous dose distribution is the most important factor for local control in interstitial radiotherapy. With the use of I-125 seeds this can only be achieved in small-volume (T2) stages with refined technique. For larger tumor volumes (T3) an external boost or the use of other radionuclides is preferable.
authors: Abteilung für Urologie, Klinikum der Universität Freiburg.
authors: H
authors: H
authors: Sommerkamp
authors: M
authors: M
authors: Rupprecht
authors: G
authors: G
authors: Bruggmoser
authors: M
authors: M
authors: Wannenmacher
mesh_terms: D000368:Aged; D001918:Brachytherapy / Q000379:methods*; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D011879:Radiotherapy Dosage
chemical_list: D007457:Iodine Radioisotopes
vernacular_title: Determinanten der lokalen Tumorkontrolle in der interstitiellen Strahlentherapie des Prostatakarzinoms.