Nortriptyline in the treatment of panic disorder and agoraphobia with panic attacks.
Thirty-four consecutive patients with panic disorder or agoraphobia with panic attacks were treated with nortriptyline at the LAC-USC Medical Center's Anxiety Disorders Clinic. Fourteen (67%) of the 21 completers totally lost their panic attacks, five (24%) showed partial improvement, and two (10%) showed no improvement. The relationship of treatment outcome to pretreatment and posttreatment measures of depression is discussed, in addition to the potential role of nortriptyline in treating panic attacks in clinical practice.
Munjack
D J
DJ
Department of Psychiatry, Los Angeles County-University of Southern California Medical Center 90033.
Usigli
R
R
Zulueta
A
A
Crocker
B
B
Adatia
N
N
Buckwalter
J G
JG
Baltazar
P
P
Kurvink
W
W
Inglove
H
H
Kelly
R
R
D000328:Adult; D000379:Agoraphobia / Q000188:drug therapy*; D000704:Analysis of Variance; D005239:Fear / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009661:Nortriptyline / Q000627:therapeutic use*; D010200:Panic / Q000187:drug effects*; D010698:Phobic Disorders / Q000188:drug therapy*
D009661:Nortriptyline