title: MR imaging section profile optimization: improved contrast and detection of lesions.
abstract: A computer-optimized radio-frequency (RF) pulse for sharper section definition was implemented for T2-weighted magnetic resonance (MR) imaging of the head. Twenty-four patients underwent MR imaging with this technique and also with a conventional spin-echo technique with a sinc pulse filtered with a Hamming window. The contrast between gray and white matter improved 20%-40%, depending on the echo time. In ten patients with multiple sclerosis, use of the computer-optimized RF pulse resulted in detection of 37% more lesions, and power deposition was reduced by 36%. The computer-optimized RF pulse improved image contrast and lesion detection.
authors: Department of Radiology, New England Medical Center Hospitals, Boston, MA 02111.
authors: V M
authors: VM
authors: Runge
authors: M L
authors: ML
authors: Wood
authors: D M
authors: DM
authors: Kaufman
authors: M S
authors: MS
authors: Silver
mesh_terms: D001921:Brain / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009103:Multiple Sclerosis / Q000473:pathology