Arginine-induced hypermagnesemia and hyperkalemia in nephrectomized rats.
This study examined the effect of arginine monohydrochloride infusion on serum Mg and K in nephrectomized rats. Hyperkalemia exceeded the hypermagnesemia both of which occurred in response to arginine infusion and/or metabolic acidosis. This observation is consonant with our earlier reports which demonstrated that the activity of K exceeded that of Mg in shifts between the intracellular and extracellular compartments under a variety of experimental conditions.
Whang
R
R
Department of Medicine, University of Oklahoma College of Medicine, Oklahoma City.
Papper
S
S
Llach
F
F
D000138:Acidosis / Q000097:blood / Q000139:chemically induced; D000818:Animals; D001120:Arginine / Q000494:pharmacology*; D002451:Cell Compartmentation / Q000187:drug effects; D008274:Magnesium / Q000097:blood*; D008297:Male; D009392:Nephrectomy; D011188:Potassium / Q000097:blood*; D051381:Rats; D011919:Rats, Inbred Strains
D001120:Arginine; D008274:Magnesium; D011188:Potassium