[Description of the kinetics of allosteric polymeric enzymes with 2 ligands based on the generalized Ising model].
The two-ligand model for allosteric regulation of complex polymeric enzymes is offered. Two types of cooperative interactions are observed--the cooperative transformations inside the promoter and interactions of promoters themselves--along with the direct interaction of two ligands inside each subunit. The solution of the model is given and its kinetic properties are discussed.
Cherepanov
D A
DA
D000494:Allosteric Regulation; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D008024:Ligands; D008433:Mathematics; D008954:Models, Biological; D011108:Polymers; D011487:Protein Conformation
D004798:Enzymes; D008024:Ligands; D011108:Polymers
Opisanie kinetiki allostericheskikh polimernykh fermentov s uchastiem dvukh ligandov na osnove obobshchennoĭ modeli Izinga.