Basic module for an adaptive control system based on neurone information processing.
The design of such devices as robotic aids for handicapped people, powered prostheses and manipulative aids such as page turners would benefit from the use of an adaptive control system. Much recent work on adaptive networks has been based on simplified models of the information processing capabilities of neurones. Neurones are now known to be capable of association learning and memory and this study incorporates these features in a neurone model. A single neuronal input system, the NMDA-type glutamate receptor, is modelled by deriving finite difference equations from its reaction dynamics so that the concentration of several molecules in the receptor can be plotted as a function of time. The model shows association learning taking place at the glutamate receptor. A whole neurone with ten glutamate receptor regions is also modelled and shows that a neurone should be capable of recognizing patterns of inputs. As the neurone model is complicated and slow to run, a much simplified form of the model is described which embodies the basic features of neurone information processing in a simple algorithm.
Orpwood
R D
RD
Bath Institute of Medical Engineering, St Martin's Hospital, Wellsway, UK.
D000465:Algorithms; D001698:Biomedical Engineering; D003198:Computer Simulation; D008564:Membrane Potentials; D008959:Models, Neurological; D009473:Neuronal Plasticity; D013569:Synapses / Q000502:physiology