Multiple head and neck neoplasia following radiation for benign disease during childhood.
A woman received radiation therapy to the adenoids for benign disease at the age of 10 years and subsequently developed an adenocarcinoma of the middle ear, a parathyroid adenoma, and a papillary carcinoma of the thyroid gland in adulthood. This appears to be the first such case on record. The literature of neoplasia after head and neck irradiation is briefly reviewed.
Sirota
D K
DK
Department of Medicine, Mount Sinai School of Medicine, New York, New York 10029.
Eden
A R
AR
Biller
H F
HF
D000230:Adenocarcinoma / Q000209:etiology; D000234:Adenoids / Q000528:radiation effects; D000236:Adenoma / Q000209:etiology; D000328:Adult; D002291:Carcinoma, Papillary / Q000209:etiology; D002648:Child; D004428:Ear Neoplasms / Q000209:etiology; D004432:Ear, Middle; D005260:Female; D006258:Head and Neck Neoplasms / Q000209:etiology*; D006801:Humans; D009378:Neoplasms, Multiple Primary; D010282:Parathyroid Neoplasms / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D013964:Thyroid Neoplasms / Q000209:etiology