Severe ethylene glycol butyl ether poisoning. Kinetics and metabolic pattern.
A case of severe poisoning with ethylene glycol butyl ether (EGBE) after massive ingestion is described. Deep coma, metabolic acidosis, hypokalaemia, haemoglobinuria, oxaluria and a transitory rise in the serum creatinine level were observed. The elimination of the various metabolites butoxyacetic acid and oxalate was assessed in urine and a metabolic pattern for EGBE is suggested.
Rambourg-Schepens
M O
MO
Centre Anti-Poisons, S.A.M.U., Reims, France.
Buffet
M
M
Bertault
R
R
Jaussaud
M
M
Journe
B
B
Fay
R
R
Lamiable
D
D
D003401:Creatine / Q000378:metabolism; D005026:Ethylene Glycols / Q000378:metabolism / Q000506:poisoning*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010070:Oxalates / Q000378:metabolism; D013406:Suicide, Attempted
D005026:Ethylene Glycols; D010070:Oxalates; C017096:n-butoxyethanol; D003401:Creatine