[Anatomo-clinical study of Behçet's syndrome with involvement of the central nervous system].
The authors report a patient with Behçet disease who developed severe central neurological disturbances. The M.R.I. was largely coincident with the distribution of the lesions verified in the neuropathological examination, while CT only shows an hypodense lesion in basal ganglia with contrast enhancement. The neurological symptoms did not respond to a treatment with prednisone and azathioprine. The main histopathological findings are similar to those described by previous observers. Reactive histiocytic infiltration with severe lymphocytic phagocytosis, probably related to immunosuppressor treatment, was also observed.
Martinez
J M
JM
Service de Neurologie, Hôpital de la Santa Creu i Sant Pau, Barcelone.
Barraquer-Bordas
L
L
Ferrer
I
I
Escartin
A E
AE
Rosich
M
M
Barraquer-Feu
M L
ML
D001379:Azathioprine / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D001921:Brain / Q000473:pathology; D002493:Central Nervous System Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010586:Phagocytes / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D001379:Azathioprine; D011241:Prednisone
Etude anatomo-clinique d'un syndrome de Behçet, avec atteinte du système nerveux central.