[Localization of enolase in the cancer nest of digestive organs].
Gamma-enolase, otherwise called neuron specific enolase (NSE), is specific for neural and neuro-endocrine systems and is present in the tumors of these systems. Gamma-enolase is also reported to be present, however, in a localized form in the tissues of other nonneural systems in some cases of lung cancer in relatively large number of incidences. We examined immunohistologically specimens of digestive organ cancers. Two principal conclusions were obtained. First, gamma-enolase is not specific for neural and neuro-endocrine systems. Second, gamma-enolase is localized in the epithelium of cancers of some cases following the transformation into cancer.
Usami
S
S
Surgical Department, Kariya General Hospital, Japan.
Hayashi
S
S
Ohkubo
T
T
Kotani
H
H
Kato
K
K
Haimoto
H
H
D014408:Biomarkers, Tumor / Q000032:analysis; D004067:Digestive System Neoplasms / Q000201:enzymology*; D006801:Humans; D010751:Phosphopyruvate Hydratase / Q000032:analysis*
D014408:Biomarkers, Tumor; D010751:Phosphopyruvate Hydratase