Long-term depressor effects of noradrenaline and dopamine neurons transplanted into the third ventricle of the brain of salt-loaded hypertensive rats.
Neural tissues including A 6 group noradrenaline neurons in the locus ceruleus or A 10 group dopamine neurons in the substantia nigra were transplanted into the third ventricle at the preoptic-anterior hypothalamic level of rats made hypertensive by salt loading. Either transplant exerted a long-lasting depressor effect.
Hashimoto
R
R
Department of Physiology, Yokohama City University School of Medicine, Japan.
Kimura
F
F
D000818:Animals; D001794:Blood Pressure; D001921:Brain / Q000502:physiology*; D004298:Dopamine / Q000378:metabolism*; D006973:Hypertension / Q000139:chemically induced / Q000503:physiopathology*; D008125:Locus Coeruleus / Q000637:transplantation; D008297:Male; D009474:Neurons / Q000502:physiology* / Q000637:transplantation; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012965:Sodium Chloride; D013378:Substantia Nigra / Q000637:transplantation
D012965:Sodium Chloride; D004298:Dopamine; D009638:Norepinephrine