A case-control study of prostatic cancer with reference to dietary habits.
A case-control study of prostatic cancer which consisted of 100 patients with prostatic cancer, matched for hospital, age (+/- 3 yr) and hospital admission date (+/- 3 months) to patients with benign prostatic hyperplasia (BPH) and hospital controls, was conducted from 1981 to 1984. Low daily intake of beta-carotene (RR = 2.13: 95% confidence interval, 1.20-3.77) and of vitamin A (RR = 1.94: 1.10-3.43), as compared to the intake of those substances by BPH controls, were factors significantly correlated with the development of prostatic cancer. Low daily intake of beta-carotene (RR = 2.13: 1.20-3.77), as compared with hospital controls, were significantly correlated with prostatic cancer development. Infrequent intake of bread (RR = 2.40: 1.31-4.38), intended to represent a westernized diet, and of spinach (RR = 1.96: 1.01-7.73), a typical green and yellow vegetable, as compared to BPH controls and infrequent intake of spinach (RR = 4.55: 1.82-11.11) as compared to by hospital controls, were significant risk factors for prostatic cancer. Intake of carbohydrates, protein, fat, total calories, fibers, vitamin B and vitamin C were not correlated with the development of prostatic cancer.
Oishi
K
K
Department of Urology, Kyoto University, Japan.
Okada
K
K
Yoshida
O
O
Yamabe
H
H
Ohno
Y
Y
Hayes
R B
RB
Schroeder
F H
FH
D000368:Aged; D001487:Basidiomycota; D001939:Bread; D002338:Carotenoids; D004032:Diet / Q000009:adverse effects*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009747:Nutritional Physiological Phenomena; D011471:Prostatic Neoplasms / Q000209:etiology*; D012307:Risk Factors; D014801:Vitamin A; D019207:beta Carotene
D019207:beta Carotene; D014801:Vitamin A; D002338:Carotenoids