Estrogen receptor content in primary breast carcinomas and their metastases.
The estrogen receptor content was measured in 25 primary human mammary carcinomas. These values were compared to those in metastases which were detected between 0-108 months after mastectomy. There was a good correlation between the receptor level in the primary tumor and in its metastasis. This finding does not support the hypothesis that metastases in general represent a selection of poorly differentiated receptor-poor cell clones from the primary tumors.
Tani
E
E
Department of Pathology, Karolinska Hospital, Stockholm, Sweden.
Nordenskjöld
B
B
Humla
S
S
Skoog
L
L
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011960:Receptors, Estrogen / Q000378:metabolism*; D013997:Time Factors
D011960:Receptors, Estrogen