[Excretion of monoamines, their precursors and metabolites in the hyperactivity syndrome in mentally defective children].
Alterations on dynamics of excretion with urine of dopamine, noradrenaline, vanilylmandelic acid and N1-methyl nicotinamide were detected in 7-11 years old children with mental insufficiency accompanied by effective component of the hyperdynamic syndrome in the course of treatment with sidnocarb and sonapax. Sidnocarb was shown to alter positively the excretion of noradrenaline and sonapax--that of N1-methyl nicotinamide. Clinical features of the hyperdynamic syndrome should be taken into consideration in prescription of drug therapy.
Turova
N F
NF
Misionzhnik
E Iu
EIu
Ermolina
L A
LA
Aziavchik
A V
AV
Krasov
V A
VA
D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy / Q000378:metabolism* / Q000652:urine; D001679:Biogenic Amines / Q000378:metabolism* / Q000652:urine; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011619:Psychotropic Drugs / Q000627:therapeutic use; D013558:Sydnones / Q000627:therapeutic use
D001679:Biogenic Amines; D011619:Psychotropic Drugs; D013558:Sydnones; C009257:sidnocarb
Ekskretsiia monoaminov, ikh predshestvennikov i metabolitov pri giperaktivnom sindrome u deteĭ s intellektual'noĭ nedostatochnost'iu.