The human liver-type pyruvate kinase (PKL) gene is on chromosome 1 at band q21.
Pyruvate kinase (PK) is an important enzyme for ATP production in the glycolytic pathway. Deficiency of this enzyme in erythrocytes is characterized by hemolytic anemia. Using in situ hybridization, we have mapped the human liver-type pyruvate kinase gene (PKL) to band q21 of chromosome 1.
Satoh
H
H
Chromosome Research Unit, Faculty of Science, Hokkaido University, Sapporo, Japan.
Tani
K
K
Yoshida
M C
MC
Sasaki
M
M
Miwa
S
S
Fujii
H
H
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D006801:Humans; D007621:Karyotyping; D008099:Liver / Q000201:enzymology*; D011770:Pyruvate Kinase / Q000172:deficiency / Q000235:genetics*
D011770:Pyruvate Kinase