Inclusion mode of flurbiprofen with beta-cyclodextrin and heptakis(2,3,6-tri-O-methyl)-beta-cyclodextrin, and improvements of some pharmaceutical properties of flurbiprofen by complexation.
Imai
T
T
Otagiri
M
M
Saitô
H
H
Uekama
K
K
D000818:Animals; D002626:Chemistry, Pharmaceutical; D003505:Cyclodextrins; D005480:Flurbiprofen / Q000008:administration & dosage / Q000493:pharmacokinetics*; D007408:Intestinal Absorption; D011422:Propionates / Q000493:pharmacokinetics*; D011817:Rabbits; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D011422:Propionates; D047392:beta-Cyclodextrins; D005480:Flurbiprofen; C031215:betadex