Human sperm chromosomes.
Sperm chromosome studies have been performed in 70 normal males. The incidence of aneuploidy in this group is approximately 3-4%, and that of structural anomalies close to 5%. In carriers of reciprocal or Robertsonian translocations, the results are extremely variable, with percentages of unbalanced sperm from 8 to 87%. No unbalanced spermatozoa have been observed in patients with pericentric or paracentric inversions. In cancer patients treated with radio and/or chemotherapy, the incidence of chromosome abnormalities is much higher, and significantly different from that found in controls.
Templado
C
C
Departamento de Biologia Celular y Fisiologia, Universidad Autónoma de Barcelona, Spain.
Benet
J
J
Genescà
A
A
Navarro
J
J
Caballin
M R
MR
Mirò
R
R
Egozcue
J
J
D000782:Aneuploidy; D002869:Chromosome Aberrations; D007446:Chromosome Inversion; D002877:Chromosomes, Human / Q000187:drug effects / Q000528:radiation effects; D006801:Humans; D008297:Male; D013094:Spermatozoa / Q000648:ultrastructure*; D014178:Translocation, Genetic