title: [ST segment changes in long-term ECG in healthy heart probands].
abstract: 100 healthy medical students were studied with 24-h Holter monitoring for ST-segment evaluation. Six recordings (1.8% of males and 11.6% of females) contained at least one episode of horizontal or downsloping ST-segment depression of at least 0.1 mV or more and 1 min duration in the V-5-like lead. Since ST-segment elevations (in 73% of the recordings in the V-5-like lead, and in 40% in the V-2-like lead) and discordant (negative) T-waves associated with ST-segment depressions (in 31% of the recordings in the V-2-like lead) were commonly seen, these ECG findings have to be considered as nonspecific. During exercise tests using a protocol of maximal work load, not one of these healthy individuals displayed typical ST-segment depressions indicative of myocardial ischemia. Therefore, typical documented ST-segment alterations in Holter-ECG recordings should be used with caution when observed in individuals with suspected coronary heart disease, particularly when they are female.
authors: Medizinische Klinik III der Universität zu Köln.
authors: I
authors: I
authors: Treis-Müller
authors: A
authors: A
authors: Osterspey
authors: A
authors: A
authors: Loskamp
authors: T
authors: T
authors: Eggeling
authors: H
authors: H
authors: Günther
authors: H W
authors: HW
authors: Höpp
authors: V
authors: V
authors: Hombach
mesh_terms: D000293:Adolescent; D000328:Adult; D003327:Coronary Disease / Q000175:diagnosis*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D012016:Reference Values
vernacular_title: ST-Segment-Veränderungen im Langzeit-EKG bei Herzgesunden.