Elastosis in the male breast.
Elastosis, a common finding in infiltrating ductal and lobular carcinomas of the female breast, has also been described in a variety of other benign and malignant lesions. However, elastosis has not been previously documented in male breast lesions. Ten cases of gynaecomastia and five neoplastic lesions of the male breast were evaluated for elastosis. In gynaecomastia, elastosis is a feature of the ducts surrounded by collagenized fibrous tissue but not of ducts with loose connective tissue stroma. This association is also evident to some extent in neoplastic lesions. These findings suggest that elastosis is an expression of periductal fibrosis irrespective of the nature of the lesion.
Raju
G C
GC
Department of Pathology, National University of Singapore, Republic of Singapore.
Lee
Y S
YS
D001940:Breast / Q000002:abnormalities* / Q000648:ultrastructure; D001943:Breast Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D004547:Elastic Tissue / Q000473:pathology* / Q000648:ultrastructure; D006177:Gynecomastia / Q000473:pathology; D006801:Humans; D008297:Male