Effect of hematocrit concentration on blood glucose value determined on Glucometer II.
Nineteen patient blood samples each with modified hematocrit concentrations of approximately 20, 30, 40, 50, and 60%, were assayed for their glucose concentration by the Glucometer II. Blood removal from the test strip was by the one- and two-blot techniques. The reference method was the Yellow Springs Instruments (YSI) blood glucose analyzer. Glucometer II results were falsely high for the single blot (13-59%, mean 33%) and double blot (12-41%, mean 19%) at 20% hematocrit and falsely low at 60% hematocrit for the single blot (22-44%, mean 37%) and the double blot (26-49%, mean 43%). At 40-50% hematocrit, Glucometer II and YSI results agreed only for the one-blot technique.
Barreau
P B
PB
Department of Clinical Chemistry, Queen Elizabeth Hospital, Woodville, Australia.
Buttery
J E
JE
D001786:Blood Glucose / Q000032:analysis*; D003124:Colorimetry / Q000295:instrumentation / Q000379:methods; D003920:Diabetes Mellitus / Q000097:blood*; D005188:False Negative Reactions; D005189:False Positive Reactions; D006400:Hematocrit; D006801:Humans; D011934:Reagent Strips
D001786:Blood Glucose; D011934:Reagent Strips