Anticonvulsant activity of root and stem extracts of Calliandra portoricensis.
A comparative study of the anticonvulsant properties of root and stem extracts of Calliandra portoricensis was carried out in mice. The convulsion models were pentylenetetrazole- and electroshock-induced convulsions. The results showed that the aqueous extracts of both root and stem possess anticonvulsant activity when given intraperitoneally. An alkaloidal extract did not show any anticonvulsant action up to 316 mg/kg i.p.
Akah
P A
PA
Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka.
Nwaiwu
J I
JI
D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D004597:Electroshock; D051379:Mice; D008815:Mice, Inbred Strains; D009549:Nigeria; D010433:Pentylenetetrazole / Q000633:toxicity; D010936:Plant Extracts / Q000032:analysis / Q000494:pharmacology; D010946:Plants, Medicinal / Q000032:analysis*
D000927:Anticonvulsants; D010936:Plant Extracts; D010433:Pentylenetetrazole