Application of Folin-Ciocalteu reagent for the spectrophotometric determination of some nonsteroidal antiinflammatory agents.
A simple, sensitive, accurate, and rapid method for the quantitative determination of naproxen, oxyphenbutazone, mefenamic acid, indomethacin, and diclofenac sodium in pharmaceutical preparations is proposed. The method is based on the formation of blue complexes with Folin-Ciocalteu reagent.
Sastry
C S
CS
Department of Organic Chemistry, Foods, Drugs, and Water, School of Chemistry, Andhra University, Waltair, India.
Rao
A R
AR
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D007202:Indicators and Reagents; D008982:Molybdenum; D013053:Spectrophotometry / Q000379:methods; D014414:Tungsten; D017973:Tungsten Compounds
D000894:Anti-Inflammatory Agents, Non-Steroidal; C029556:Folin's phenol reagent; D007202:Indicators and Reagents; D017973:Tungsten Compounds; D008982:Molybdenum; D014414:Tungsten