Contact dermatitis from a compound mixture of sugar and povidone-iodine.
2 patients with leg ulcers got worse after the application of a compound mixture of sugar and povidone-iodine (sugar/PI compound). Because they had been suffering from stasis dermatitis, symptoms of contact dermatitis were ambiguous. Patch tests showed positive reactions to 10% povidone-iodine in water and 5% potassium iodide in water, with no response to sugar. They were also tested with sugar/PI compound, containing 3% povidone-iodine, resulting in another positive reaction. They improved after the application of sugar/PI compound was discontinued. Contact dermatitis from topical agents should be considered as more probable than angry back syndrome in cases of leg ulcer.
Kudo
H
H
Department of Dermatology, Faculty of Medicine, Kyoto University, Japan.
Takahashi
K
K
Suzuki
Y
Y
Tanaka
T
T
Miyachi
Y
Y
Imamura
S
S
D000368:Aged; D000369:Aged, 80 and over; D003877:Dermatitis, Contact / Q000209:etiology*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000188:drug therapy*; D008875:Middle Aged; D010328:Patch Tests; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000009:adverse effects* / Q000627:therapeutic use; D013395:Sucrose
D004338:Drug Combinations; D013395:Sucrose; D011206:Povidone-Iodine; D011205:Povidone