Acute confusional state with status petit mal as a withdrawal syndrome--and five year follow-up.
A 55 year old man developed an acute confusional state with grossly impaired short-term memory accompanied by a Status Petit Mal epilepsy pattern on EEG, one to two weeks after abruptly discontinuing a large amount of oxazepam and a smaller amount of alcohol. Both his mental status and EEG pattern normalized markedly after intravenous diazepam. On 5 year follow-up the patient was seizure-free and medication-free without any significant residual cognitive deficit.
Hersch
E L
EL
Department of Psychiatry, Sunnybrook Medical Centre, Toronto, Ontario.
Billings
R F
RF
D000208:Acute Disease; D003072:Cognition Disorders / Q000139:chemically induced*; D003221:Confusion / Q000139:chemically induced*; D003975:Diazepam / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010076:Oxazepam / Q000009:adverse effects*; D013226:Status Epilepticus / Q000139:chemically induced*; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy; D013997:Time Factors
D010076:Oxazepam; D003975:Diazepam