[Obsessive-compulsive behavior caused by bilateral lesions of the lenticular nuclei. A new case].
Another case of obsessive behaviour as the consequence of lentiform nuclei lesions is reported. All the aspects of an obsessive neurosis were present: irresistible compulsiveness, acute anxiety in case of non accomplishment, magic-like clues. The symptoms appeared after a carbon monoxide poisoning, in a 31-years-old woman who had previously a pathological personality, of the psychopathic type, but without obsessive features. The onset of compulsions was paralleled by frontal-like psychological changes, but there was no reduction of intellectual or mnesic functions. A previous depressive state continued after the poisoning, so that the patient did not show an empty mind as did the other patients; the loss of "self-psychic activation" was only partial. All these case-reports emphasize the fact that the neuropsychological testing must not be limited to the behaviour and must investigate the "mental content" as well. They also lead us to emphasize similitudes between psychic disorders related to lenticular lesions and those related to frontal lobe lesions, including obsessive-like activities. Such case-reports provide a model in which some components of the obsessive neurosis, hebephrenia and depression are the consequence of an identified brain damage. It can be suggested that the neural circuits involving frontal lobes and parts of the neostriatum and of the pallidum are implicated in the mechanisms of these three types of psychoses.
Laplane
D
D
Service de Neurologie, CHU Pitié-Salpêtrière, Paris.
Boulliat
J
J
Baron
J C
JC
Pillon
B
B
Baulac
M
M
D000328:Adult; D002249:Carbon Monoxide Poisoning / Q000150:complications; D003342:Corpus Striatum / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009336:Necrosis; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D013997:Time Factors
Comportement compulsif d'allure obsessionnelle par lésion bilatérale des noyaux lenticulaires. Un nouveau cas.