title: Chromosome abnormalities in peripheral blood lymphocytes from untreated Hodgkin's patients. A possible evidence for chromosome instability.
abstract: We describe the presence of a high frequency of spontaneous chromosome aberrations in lymphocytes from six untreated patients with Hodgkin's disease. The characteristics of the chromosome abnormalities observed suggest the existence of a certain degree of chromosome instability in these cases, that could be a predisposing factor for the development of malignancies.
authors: Departament de Biologia Cel.lular i Fisiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
authors: L
authors: L
authors: Barrios
authors: M R
authors: MR
authors: Caballín
authors: R
authors: R
authors: Mirò
authors: C
authors: C
authors: Fuster
authors: G
authors: G
authors: Berrozpe
authors: A
authors: A
authors: Subías
authors: X
authors: X
authors: Batlle
authors: J
authors: J
authors: Egozcue
mesh_terms: D000293:Adolescent; D000328:Adult; D002869:Chromosome Aberrations; D005260:Female; D006689:Hodgkin Disease / Q000235:genetics*; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged