3-Methylhistidine/creatinine ratio in urine from low-birth-weight infants. Clinical approach.
Single urine voidings were collected twice a week in the clinical course of 12 low-birth-weight infants (gestational age: 31.8 +/- 2.8 weeks; birth weight: 1,383 +/- 308 g) and analyzed for 3-methylhistidine and creatinine. The mean 3-methylhistidine/creatinine ratio for 6 healthy, well-fed, growing low-birth-weight infants was 20.2 +/- 1.9 mumol/mmol. In the clinical course of single individuals a rise of urinary 3-methylhistidine/creatinine ratio was observed in cases of acute infection and/or low energy supply (less than 100 kcal/kg/day) frequently coupled with insufficient weight gain. Mean 3-methylhistidine/creatinine ratios in infants with hyaline membrane syndrome under artificial respiration were generally higher than in the controls matched for energy supply.
Hülsemann
J
J
Forschungsinstitut für Kinderenährung, Dortmund, FRG.
Kordass
U
U
Sander
G
G
Schmidt
E
E
Schöch
G
G
D001835:Body Weight; D003404:Creatinine / Q000652:urine*; D004032:Diet; D005260:Female; D006639:Histidine / Q000031:analogs & derivatives*; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight / Q000652:urine*; D007231:Infant, Newborn; D007234:Infant, Premature / Q000652:urine; D008297:Male; D008762:Methylhistidines / Q000652:urine*
D008762:Methylhistidines; D006639:Histidine; D003404:Creatinine; C028118:3-methylhistidine