[Prevention of disorders of the electric stability of the heart in experimental infarct using adaptation to hypoxia].
It has been shown on rats preadapted to hypoxia in an altitude chamber that myocardial infarction induced by ligation of the coronary artery was accompanied by less disturbances in the electrical stability of the heart, namely by a twofold decrease in ventricular fibrillation threshold and a considerable decrease in the heart ectopic activity. Preliminary adaptation provided the maintenance of myocardial contractility in infarction.
Ustinova
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MeersonFZ
D000222:Adaptation, Physiological; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000517:prevention & control*; D001273:Atmosphere Exposure Chambers; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications*; D051381:Rats; D011919:Rats, Inbred Strains
Preduprezhdenie narusheniĭ élektricheskoĭ stabil'nosti serdtsa pri éksperimental'nom infarkte s pomoshch'iu adaptatsii i gipoksii.