[Comparative analysis of brain neurite-stimulating protein and nerve growth factor by using a culture of chick embryo sensory neurons].
The effect of brain neurite-stimulating protein (BNSP) on growth and differentiation of nerve cells was studied in cultured chick embryo neurons BNSP stimulated axon growth. Its chemical characteristics were different from those of neurotrophic factor (NGF). The effect of NGF antiserum was not blocked by the BNSP action. The neurite-stimulating effect of BNSP can be used for stimulation of regenerating processes in the nervous tissue.
Goncharova
V P
VP
Akoev
G N
GN
Romaniuk
A V
AV
Chalisova
N I
NI
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002642:Chick Embryo; D005727:Ganglia, Spinal / Q000187:drug effects / Q000254:growth & development; D007106:Immune Sera / Q000494:pharmacology; D008247:Lysosomes / Q000378:metabolism*; D008970:Molecular Weight; D009414:Nerve Growth Factors / Q000276:immunology / Q000494:pharmacology*; D009419:Nerve Tissue Proteins / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000494:pharmacology*; D009475:Neurons, Afferent / Q000187:drug effects*; D009924:Organ Culture Techniques; D010455:Peptides / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000494:pharmacology*; D013268:Stimulation, Chemical
D007106:Immune Sera; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; D010455:Peptides; C047805:neurite-inducing factor
Sravnitel'nyĭ analiz mozgovogo neĭrit-stimuliruiushchego belka i faktora rosta nervov s ispol'zovaniem kul'tury sensornykh neĭronov kurinykh émbrionov.