title: [Vaginal tumor--an initial manifestation of malignant histiocytosis].
abstract: An anaplastic vaginal tumour was diagnosed in a 29-year-old woman. Before the planned operation leukocytosis and thrombocytopenia developed and further diagnostic tests revealed malignant histiocytosis with bone-marrow infiltration, leukaemic wash-out and tumour formation in the lower pelvis. Intensive chemotherapy, as for acute myeloid leukaemia, achieved full remission. The case demonstrates that, although rare, tumorous organ infiltration may be the initial manifestation of malignant histiocytosis. Its early diagnosis and treatment decisively affects the prognosis.
authors: Abteilung Hämatologie/Onkologie, Universität Göttingen.
authors: M
authors: M
authors: Kneba
authors: M
authors: M
authors: Bergholz
authors: A
authors: A
authors: Schauer
authors: G A
authors: GA
authors: Nagel
authors: G
authors: G
authors: Krieger
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D002277:Carcinoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D054747:Histiocytic Sarcoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D014621:Vagina / Q000473:pathology; D014625:Vaginal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
vernacular_title: Vaginaltumor--Erstmanifestation einer malignen Histiozytose.