Postoperative spindle-cell nodule of the endometrium.
The clinical and pathologic features of a case of postoperative spindle-cell nodule within the endometrium are reported, a lesion hitherto undescribed in this site. The nodule was found in the hysterectomy specimen from a 75-year-old woman, 2 1/2 weeks after a dilatation and curettage had revealed a well-differentiated endometrial adenocarcinoma. On histologic examination, the lesion consisted of a densely cellular proliferation of mitotically active spindle cells, which was initially interpreted as sarcoma. Postoperative spindle-cell nodules of the genitourinary tract are reparative proliferations of fibroblastic-type cells that should be distinguished from sarcoma on histologic examination.
Clement
P B
PB
Department of Pathology, Vancouver General Hospital, British Columbia, Canada.
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D003937:Diagnosis, Differential; D004107:Dilatation and Curettage; D004717:Endometrium / Q000473:pathology*; D005260:Female; D006801:Humans; D008593:Menopause; D011183:Postoperative Complications / Q000473:pathology*; D012509:Sarcoma / Q000473:pathology*; D014592:Uterine Hemorrhage / Q000601:surgery; D014594:Uterine Neoplasms / Q000473:pathology*