title: Immunological cross-reactivity between pseudocapsular antigens of strains of Staphylococcus aureus isolated from cases of bovine mastitis.
abstract: An assay was developed to measure the degree of immunological cross-reactivity between the pseudocapsules of a vaccine (reference) strain of Staphylococcus aureus and pseudocapsules of strains of S. aureus isolated from cases of bovine mastitis. The field strains were obtained from Australia, New Zealand, Norway, the U.K. and the U.S.A. There was large variation among strains in cross-reactivity of their pseudocapsules with those of the reference strain. For 104 Australian strains, the range of cross-reactivity indices (CRI) was 6.1-63.2% (on a scale of 0-100%, with 0% being complete identity and 100% being nil identity); for 61 overseas strains the range of CRI values was 25.7-72.1%. The data indicated that pseudocapsule antigens of Australian strains were antigenically more closely related to those of the reference strain than were pseudocapsular antigens of strains from the 4 other countries.
authors: CSIRO, Division of Animal Health, Armidale, NSW, Australia.
authors: D L
authors: DL
authors: Watson
authors: N A
authors: NA
authors: Franklin
mesh_terms: D000818:Animals; D000940:Antigenic Variation; D000942:Antigens, Bacterial / Q000276:immunology*; D001315:Australia; D001428:Bacterial Vaccines / Q000276:immunology*; D002417:Cattle; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D008414:Mastitis, Bovine / Q000382:microbiology*; D009520:New Zealand; D009664:Norway; D013211:Staphylococcus aureus / Q000276:immunology*; D006113:United Kingdom; D014481:United States
chemical_list: D000942:Antigens, Bacterial; D001428:Bacterial Vaccines