title: Hypophysectomy does not disturb the sleep-waking cycle in the cat.
abstract: The ablation of the hypophysis does not disturb the basic waking-sleep cycle. Further, this intervention fails to modify the recovery of sleep after instrumental paradoxical sleep deprivation as well as after injection of 5-hydroxytryptophan in parachlorophenylalanine-pretreated insomniac cats. These results demonstrate that the hypophysis does not play a significant role in sleep mechanisms. We discuss these data in view of a possible regulation of the sleep-waking cycle by hypothalamo-hypophyseal hormones.
authors: Département de Médecine Expérimentale, Université Claude Bernard, INSERM U52, C.N.R.S. UA1195, Lyon, France.
authors: M
authors: M
authors: Sallanon
authors: C
authors: C
authors: Buda
authors: M
authors: M
authors: Puymartin
authors: M
authors: M
authors: Denoyer
authors: K
authors: K
authors: Kitahama
authors: M
authors: M
authors: Jouvet
mesh_terms: D000818:Animals; D002415:Cats; D005260:Female; D007016:Hypophysectomy; D008297:Male; D010902:Pituitary Gland / Q000502:physiology*; D012890:Sleep / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology*