title: Are dyspeptic symptoms in patients with Campylobacter pylori-associated type B gastritis linked to delayed gastric emptying?
abstract: In this paper, the association of gastric Campylobacter pylori (CP) colonization with histologic findings and gastric emptying of a mixed solid-liquid meal was prospectively investigated in 43 consecutive patients with essential non-ulcer dyspepsia (ENUD). Gastric emptying was also measured in 30 symptom-free control subjects. The frequency of CP infection in patients with ENUD was 44.2%. We found a strong association between gastric CP colonization and chronic antral type B gastritis. Although gastric emptying was significantly prolonged in patients with ENUD, compared with the control group (p less than 0.05), we could not detect significant differences of gastric emptying between CP-negative and CP-positive ENUD patients, both groups disclosing a similar proportion of patients with significantly delayed gastric emptying (29.2% vs 31.6%). We therefore conclude that delayed gastric emptying of a mixed solid-liquid meal is not correlated with CP-positive chronic antral type B gastritis, and does not help to explain dyspeptic symptoms, which may possibly arise in relation to gastric CP colonization.
authors: Department of Medicine, St. Josef-Hospital, Ruhr-University Bochum, FRG.
authors: M
authors: M
authors: Wegener
authors: G
authors: G
authors: Börsch
authors: J
authors: J
authors: Schaffstein
authors: C
authors: C
authors: Schulz-Flake
authors: U
authors: U
authors: Mai
authors: F
authors: F
authors: Leverkus
mesh_terms: D000328:Adult; D000368:Aged; D002169:Campylobacter Infections / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D004415:Dyspepsia / Q000209:etiology*; D005260:Female; D005746:Gastric Emptying; D005756:Gastritis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged