Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12.
A 2.0-kb thyroid peroxidase cDNA of human origin was used as probe for Southern blot hybridization of genomic DNA from human somatic cells and human-rodent somatic cell hybrids. The results showed that the gene coding for human thyroid peroxidase is located on chromosome. 2. Further analysis of hybrids derived from Burkitt lymphoma cells carrying a (2;8)(p12;q24) translocation revealed that the gene maps to the region 2pter----p12.
de Vijlder
J J
JJ
Academic Medical Center, University of Amsterdam, The Netherlands.
Dinsart
C
C
Libert
F
F
Geurts van Kessel
A
A
Bikker
H
H
Bolhuis
P A
PA
Vassart
G
G
D000818:Animals; D002051:Burkitt Lymphoma / Q000235:genetics; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000235:genetics; D006801:Humans; D006822:Hybrid Cells; D007453:Iodide Peroxidase / Q000235:genetics*; D051379:Mice; D009693:Nucleic Acid Hybridization; D014407:Tumor Cells, Cultured
D004247:DNA; D007453:Iodide Peroxidase