[Fertility studies in malignancy (tumors of the testicle, malignant melanomas, cancer of the thyroid gland)].
The examination of 83 patients suffering from tumours (78 tumours of the testicle, 4 melanoblastomas, 1 carcinoma of the thyroid gland) led to conclusions on the effect of complex therapy on spermiogenesis. By means of spermiograms carried out in the course of the illness we found out restrictions of fertility which were more distinctly marked with patients suffering from gonadal tumours than with patients suffering from extragonadal tumours. The loss in ejaculation after RLN with existing tumours of the testes has to be considered as a disturbance in fertility to the highest degree. X-ray therapy impairs spermiogenesis more than chemotherapeutics. After chemotherapy we observed a recovery of spermiogenesis, after x-ray therapy only then if there were no irreversible damages of the germinal epithelium.
Barth
V
V
Klinik für Nephrologie und Urologie des Bezirkskrankenhauses Aue, Karl-Marx-Universität Leipzig, GDR.
Schönfelder
M
M
D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000628:therapy; D012661:Semen / Q000032:analysis; D013076:Sperm Count; D013081:Sperm Motility; D013091:Spermatogenesis / Q000187:drug effects / Q000528:radiation effects; D013736:Testicular Neoplasms / Q000150:complications* / Q000628:therapy; D013964:Thyroid Neoplasms / Q000150:complications* / Q000628:therapy
Fertilitätsuntersuchungen maligner Tumoren (Hodentumoren, maligne Melanome, Schilddrüsenkarzinom).