Low stage invasive carcinoma of the uterine cervix stage I-IIA morphological prognostic factors.
Histological material was reviewed from the 213 patients who had undergone radical surgery for carcinoma of the uterine cervix stage I and IIA between 1967 and 1981. Squamous carcinoma was found in 179 patients (84.7%). In 39 patients (18%) there were lymph node metastases and in nine (4.2%) tumor spread into the parametrium. Vaso-invasion was present in 49 patients (22%). Prognostic factors were studied by Cox's regression analysis. Lymph node metastases and vaso-invasion were both found to be significantly related to survival rate (P = 0.0001 and P = 0.0008). Stage, cell type, differentiation and invasion depth were of no prognostic importance.
Kenter
G G
GG
Department of Gynaecology, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam.
Ansink
A C
AC
Heintz
A P
AP
Delemarre
J
J
Aartsen
E J
EJ
Hart
A A
AA
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D011379:Prognosis; D014594:Uterine Neoplasms / Q000401:mortality / Q000473:pathology*