[Multivariate statistical analysis of the postoperative recurrence factors in uterine cervical carcinoma].
In 211 patients with postoperative cervical carcinoma, we studied the relationship between the recurrence and various factors, and the interrelation among the factors. 1) Lymph node metastasis, clinical stage, number of complaints, adenocarcinoma and adenosquamous carcinoma, and number of pregnancies were associated with recurrence. Signs of myelic injury and large cell non-keratinizing carcinoma were associated with less recurrence. Maintenance chemotherapy markedly improved the prognosis. 2) Lymph node metastasis was frequently associated with an advanced stage, adenocarcinoma or increased erythrocyte sedimentation. Increased sedimentation was rarely associated with greater numbers of pregnancy or keratinizing carcinoma. Signs of myelic injury were rare in cases of advanced stage or large cell carcinoma and frequent in cases of long periods of illness. 3) Intrapelvic recurrence was related to early recurrence and maintenance chemotherapy, and extrapelvic recurrence to increased sedimentation, late recurrence, adenocarcinoma and no chemotherapy. 4) Early recurrence was associated with shorter periods of illness, lymph node metastasis and no chemotherapy, but late recurrence was associated with longer periods of illness, no lymph node metastasis, maintenance chemotherapy and adenocarcinoma. 5) The prognosis and the required periods of maintenance chemotherapy could be determined by Z = 4.3817.X1 + 1.2366.X2-0.0916.X3 + 2.3257.X4-1.9606.X5 + 1.6477.X6-0.1967.X7- 7.3047, with rates of inaccuracy of 13.9% for cases of no recurrence and 15.1% for recurrent cases.
Ito
T
T
Department of Obstetrics and Gynecology, Koseiren Takaoka Hospital, Toyama.
Yago
H
H
Kuribayashi
M
M
Osawa
H
H
D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D011184:Postoperative Period; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery