[Reorganization of the tubulin and vimentin components of the cytoskeleton as affected by the action of hypotonia on L cells].
Mouse transformed fibroblasts of line L show a disruption of the microtubule system and an appearance of intermediate organizing centres after 0.5-1 min of incubation in the hypotonic medium. After 30-60 min of hypotonic treatment the recovery of microtubules and the thickening of intermediate filaments around the nucleus are observed, which promotes a disguise of intermediate organizing centres.
Smirnova
E A
EA
D000818:Animals; D003599:Cytoskeleton / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D004305:Dose-Response Relationship, Drug; D006651:Histocytochemistry; D007038:Hypotonic Solutions / Q000494:pharmacology*; D007382:Intermediate Filaments / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D007739:L Cells / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D051379:Mice; D008870:Microtubules / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D013997:Time Factors; D014404:Tubulin / Q000378:metabolism*; D014746:Vimentin / Q000378:metabolism*
D007038:Hypotonic Solutions; D014404:Tubulin; D014746:Vimentin
Perestroĭka tubulinogo i vimentinovogo komponentov tsitoskeleta pri deĭstvii gipotonii na L-kletki.