Correlation of estrogen receptor protein and carcinoembryonic antigen with lymphnodal metastasis in breast carcinoma.
Estrogen receptor protein (ERP) content and carcinoembryonic antigen (CEA) positivity were analysed in 50 cases of primary breast carcinoma. Relationship of pathological features known to be of prognostic significance and combined CEA and ERP status were examined. It was found that CEA + ERP--tumours had significantly higher frequency of axillary lymphnodal metastasis in comparison to CEA - ERP + cases. Presence of CEA - or ERP + status showed significant lower frequency of metastasis in comparison to CEA + ERP - tumours.
Khemani
A K
AK
Department of Pathology, All India Institute of Medical Sciences, New Delhi.
Kapila
K
K
Sundaram
K R
KR
Verma
K
K
D001365:Axilla; D001943:Breast Neoplasms / Q000032:analysis*; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002277:Carcinoma / Q000032:analysis*; D002352:Carrier Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D011960:Receptors, Estrogen / Q000032:analysis*
D002272:Carcinoembryonic Antigen; D002352:Carrier Proteins; D011960:Receptors, Estrogen; C010140:estrophilin