title: The influence of haematocrit on blood cyclosporin measurements in vivo.
abstract: The influence of haematocrit on blood cyclosporin measurements has been studied in 276 paired blood and plasma samples from 21 renal transplant patients. A highly significant correlation was found between blood and plasma cyclosporin concentrations, r = 0.8744, but the correlation between blood or plasma cyclosporin and haematocrit was not significant. The ratio of blood/plasma cyclosporin did not significantly increase with increasing haematocrit. It was concluded that in vivo the influence of haematocrit on the measurement of blood cyclosporin concentrations was negligible.
authors: Department of Clinical Pharmacology, St Bartholomew's Hospital, London.
authors: A
authors: A
authors: Johnston
authors: J T
authors: JT
authors: Marsden
authors: D W
authors: DW
authors: Holt
mesh_terms: D003524:Cyclosporins / Q000097:blood*; D006400:Hematocrit; D006801:Humans; D011863:Radioimmunoassay
chemical_list: D003524:Cyclosporins