Topical 5-fluorouracil solution in the treatment of warts--clinical experience and percutaneous absorption.
Disseminated warts in six patients were pre-treated with topical 5-fluorouracil solution three times daily for 5 consecutive days. Curettage was then carried out under local anaesthesia. During pre-treatment less than 0.1% of the dose applied was absorbed through the skin. The warts had not reappeared in 5 of the 6 patients at follow-up 1 year later.
Senff
H
H
Department of Dermatology, Federal Armed Forces Hospital, Hamburg, West Germany.
Reinel
D
D
Matthies
C
C
Witts
D
D
D000287:Administration, Topical; D000328:Adult; D003475:Curettage; D005472:Fluorouracil / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D011292:Premedication; D012869:Skin Absorption; D013997:Time Factors; D014860:Warts / Q000188:drug therapy* / Q000601:surgery
D005472:Fluorouracil