Durable response to etoposide-loaded platelets in refractory immune thrombocytopenic purpura: a case report.
A 23-year-old female presented with widespread purpura and ecchymoses as a result of immune thrombocytopenia which was refractory to corticosteroids, splenectomy, and immunosuppressive agents. In view of the extent and serious nature of her bleeding, salvage therapy with etoposide-loaded platelets was undertaken, which was associated with a lasting complete remission.
Wood
L
L
Department of Haematology, Groote Schuur Hospital, Cape Town, South Africa.
Jacobs
P
P
D000328:Adult; D001803:Blood Transfusion; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D017713:Platelet Transfusion; D011696:Purpura, Thrombocytopenic / Q000188:drug therapy* / Q000628:therapy
D005047:Etoposide