The role of short-term multilumen duodenojejunal manometry in patients with intestinal motor dysfunction.
Short-term duodenojejunal manometry, using a multilumen perfused tube, was performed in 12 patients with symptoms of motor dysfunction, 6 patients with irritable bowel syndrome and predominant diarrhea and 6 patients with chronic constipation. Ten healthy individuals served as controls. The durations, in minutes, of the various phases of the migratory motility complex in the three groups were: phase I: 24.4 +/- 22.1, 26.9 +/- 17.3, and 27.2 +/- 18.5; phase II: 86.7 +/- 25.2, 132 +/- 93, and 73.1 +/- 40.8, and those of phase III: 6 +/- 2.5, 6.8 +/- 5, and 6.4 +/- 1.7, respectively. The differences between patients and controls were not statistically significant. Variables of contractions of phase III in the different groups were: frequency (per minute): 10.9 +/- 0.8, 10.7 +/- 0.4, and 11.3 +/- 0.4; Summation of amplitudes per minute: 205.2 +/- 55.7, 288 +/- 57.9, and 337.8 +/- 76.5; Mean amplitude (mm Hg): 19.1 +/- 4.2, 28.6 +/- 5, and 33.5 +/- 7.1, respectively. Results in the patient groups were not significantly different from controls. Short-term duodenojejunal manometry was normal in patients with irritable bowel syndrome and in those with chronic constipation.
Soffer
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Department of Gastroenterology, Edith Wolfson Hospital, Holon, Israel.
Bruck
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Bar-Meir
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S
D000328:Adult; D002908:Chronic Disease; D003248:Constipation / Q000503:physiopathology; D003967:Diarrhea / Q000503:physiopathology; D004386:Duodenum / Q000503:physiopathology; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000503:physiopathology*; D007422:Intestines / Q000503:physiopathology*; D007583:Jejunum / Q000503:physiopathology; D008297:Male; D008365:Manometry; D008875:Middle Aged; D013997:Time Factors