title: Acute transcortical mixed aphasia. A carotid occlusion syndrome with pial and watershed infarcts.
abstract: Four of 1,200 consecutive patients with their first stroke showed acute transcortical mixed aphasia (TMA) characterized by nonfluent speech with impaired naming, semantic paraphasias, echolalia, impaired comprehension, good repetition, reading, and writing on dictation. All 4 had left internal carotid artery (ICA) occlusion with ipsilateral anterior pial territory infarction (precentral-central sulcus artery territory) and watershed infarction between the middle and posterior cerebral artery territories, which spared and 'isolated' the perisylvian speech areas. Although rare, acute TMA is highly suggestive of infarction due to ICA occlusion, in that it is probably related to simultaneous embolism (anterior pial infarction) and haemodynamic insufficiency (posterior watershed infarction).
authors: Department of Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
authors: J
authors: J
authors: Bogousslavsky
authors: F
authors: F
authors: Regli
authors: G
authors: G
authors: Assal
mesh_terms: D000208:Acute Disease; D000368:Aged; D001037:Aphasia / Q000209:etiology* / Q000523:psychology; D001157:Arterial Occlusive Diseases / Q000150:complications*; D002340:Carotid Artery Diseases / Q000150:complications*; D002544:Cerebral Infarction / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010841:Pia Mater; D013577:Syndrome; D014057:Tomography, X-Ray Computed