title: Malignant pleural effusion treated by tetracycline sclerotherapy. A comparison of single vs repeated instillation.
abstract: Fifty patients with malignant pleural effusion were randomized to receive one or two doses of tetracycline sclerotherapy. We found that a single sclerotherapy treatment with tetracycline at a dose of 20 mg/kg was as effective as two sclerotherapy treatments and provided symptomatic relief in 46 of the 50 patients.
authors: Division of Cardiothoracic Surgery, George Washington University Medical Center, Washington, DC.
authors: L
authors: L
authors: Landvater
authors: W R
authors: WR
authors: Hix
authors: M
authors: M
authors: Mills
authors: R S
authors: RS
authors: Siegel
authors: B L
authors: BL
authors: Aaron
mesh_terms: D006801:Humans; D007322:Instillation, Drug; D009369:Neoplasms / Q000150:complications; D010996:Pleural Effusion / Q000209:etiology / Q000628:therapy*; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D013752:Tetracycline / Q000008:administration & dosage*
chemical_list: D012597:Sclerosing Solutions; D013752:Tetracycline