Elastase secreted by activated polymorphonuclear leukocytes causes chondrocyte damage and matrix degradation in intact articular cartilage.
Schalkwijk
J
J
Department of Rheumatology, St-Radboudhospital, Nijmegen, The Netherlands.
Joosten
L A
LA
van den Berg
W B
WB
van de Putte
L B
LB
D000818:Animals; D002358:Cartilage, Articular / Q000378:metabolism*; D002415:Cats; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D009504:Neutrophils / Q000201:enzymology*; D010196:Pancreatic Elastase / Q000097:blood*
D010196:Pancreatic Elastase