The Marfan syndrome with an XYY chromosome pattern.
A 36-year-old man who was diagnosed to have the Marfan syndrome with an XYY chromosome pattern is reported. He was tall with long limbs and arachnodactylia, and had severe aortic regurgitation (AR). The chromosome pattern studied in specimens of blood and bone marrow revealed an XYY chromosome pattern. The relationship between the Marfan syndrome and an XYY chromosome pattern is discussed.
Kanemaru
K
K
Department of Medicine, Tokyo Metropolitan Gariatric Hospital, Japan.
Ohkawa
S
S
Kuboki
K
K
Chida
K
K
Sakai
M
M
Ueda
K
K
Toyokura
Y
Y
D000328:Adult; D001022:Aortic Valve Insufficiency / Q000209:etiology; D001027:Aortography; D004452:Echocardiography; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000150:complications / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology; D010701:Phonocardiography; D012729:Sex Chromosome Aberrations; D014997:XYY Karyotype