Abnormal course of spinal posterior roots and tracts associated with brain malformations. Sensory pathway malformation.
An unusual mode of the spinal posterior nerve root entrance and of the course of ascending tracts in the hyperplastic gray matter of the posterior horn was observed in three newborn babies. This "sensory pathway malformation" was combined with severe but unspecific brain anomalies. The common associated brain anomaly was agenesis of the corpus callosum.
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Institute of Neuropathology, Medizinische Hochschule Hannover, Federal Republic of Germany.
D000015:Abnormalities, Multiple / Q000473:pathology*; D061085:Agenesis of Corpus Callosum; D001921:Brain / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D009475:Neurons, Afferent / Q000473:pathology; D013126:Spinal Nerve Roots / Q000002:abnormalities; D013127:Spinal Nerves / Q000002:abnormalities*