[Transcapillary fluid exchange in the heart infused with increasing doses of noradrenaline].
The velocity of transcapillary shift of fluid in the heart, the resistance against blood flow in the heart arterial and venous vessels, the capillary filtration coefficient were assessed in the cat isolated heart perfused with a donor--cat blood. The capillary hydrostatic pressure, at 0 and 10 mm Hg venous pressure in the heart, was 5.1 +/- 1.2 and 16.3 +/- 2.8 mm Hg, resp. Infusion of noradrenaline lowered the capillary hydrostatic pressure. The average capillary filtration coefficient was 0.22 +/- 0.03 ml/min/100 g/mm Hg in the heart and did not depend on the venous pressure. Noradrenaline increased the coefficient.
Demidov
V A
VA
Stepanova
T G
TG
Tkachenko
B I
BI
D000818:Animals; D002196:Capillaries / Q000187:drug effects / Q000502:physiology; D002200:Capillary Resistance / Q000187:drug effects; D002415:Cats; D004305:Dose-Response Relationship, Drug; D005260:Female; D005374:Filtration; D006321:Heart / Q000187:drug effects* / Q000502:physiology; D006874:Hydrostatic Pressure; D008297:Male; D009638:Norepinephrine / Q000008:administration & dosage*; D010477:Perfusion / Q000379:methods; D014882:Water-Electrolyte Balance / Q000187:drug effects*
D009638:Norepinephrine
Transkapilliarnyĭ obmen zhidkosti v serdtse pri infuzii vozrastaiushchikh doz noradrenalina.