Four-dimensional chemical shift MR imaging of phosphorus metabolites of normal and diseased human liver.
Four dimensional chemical shift imaging was used to map the relative peak heights of phosphorus metabolites of the liver and overlying skeletal muscle of a normal subject and two patients. The technique provides 31P spectra localised on a voxel-by-voxel basis and may be valuable in mapping heterogeneous structural and metabolic changes in disease.
Cox
I J
IJ
NMR Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Bryant
D J
DJ
Collins
A G
AG
George
P
P
Harman
R R
RR
Hall
A S
AS
Hodgson
H J
HJ
Khenia
S
S
McArthur
P
P
Spencer
D H
DH
D000328:Adult; D003560:Cysts / Q000378:metabolism; D005260:Female; D006801:Humans; D007565:Jaundice / Q000378:metabolism; D008099:Liver / Q000032:analysis*; D008107:Liver Diseases / Q000378:metabolism*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010758:Phosphorus / Q000032:analysis*
D010758:Phosphorus