On the plasmalogenation of myocardial choline glycerophospholipid during maturation of various vertebrates.
1. The plasmalogen profiles of a series of hearts from fish to mammals were obtained by various TLC analyses. 2. All specimens (ventricular) contained ethanolamine plasmalogen and some choline plasmalogen, as well. 3. The distribution of these two plasmalogen species was relatable, in part, to (a) phylogeny and (b) ontogeny. 4. There were exceptions. 5. The appearance of choline plasmalogen was preceded by its alkylacyl precursor, suggesting plasmalogenation by a base-specific delta 1-alkyl desaturase. 6. From the data, we have raised some questions as to the metabolic role played by the plasmalogens and precursors as occupants of myocardial mitchondrial membranes.
Hack
M H
MH
Department of Biology, Delaware State College, Dover 19901.
Helmy
F M
FM
D000818:Animals; D002855:Chromatography, Thin Layer; D009206:Myocardium / Q000378:metabolism*; D010713:Phosphatidylcholines / Q000378:metabolism*; D010955:Plasmalogens / Q000378:metabolism*; D012016:Reference Values; D013045:Species Specificity; D014714:Vertebrates / Q000254:growth & development* / Q000378:metabolism
D010713:Phosphatidylcholines; D010955:Plasmalogens