title: Small intestinal myeloid metaplasia.
abstract: Extramedullary hematopoiesis is rarely found in the gastrointestinal tract. A patient with postpolycythemic myeloid metaplasia who previously underwent splenectomy presented with recurrent, protracted gastrointestinal tract hemorrhage. Elaborate workup failed to reveal the source of bleeding. Intraoperative endoscopy with transillumination disclosed multiple submucosal lesions along the entire small bowel, which proved to be extramedullary hematopoiesis. After institution of hydroxyurea therapy, the rate of bleeding diminished considerably.
authors: Department of Internal Medicine A, Rambam Medical Center, Haifa, Israel.
authors: D
authors: D
authors: Schreibman
authors: B
authors: B
authors: Brenner
authors: R
authors: R
authors: Jacobs
authors: Y
authors: Y
authors: Ben-Arieh
authors: I
authors: I
authors: Tatarsky
authors: G
authors: G
authors: Alroy
mesh_terms: D000368:Aged; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D007410:Intestinal Diseases / Q000175:diagnosis / Q000188:drug therapy; D007421:Intestine, Small / Q000473:pathology*; D011087:Polycythemia Vera / Q000628:therapy; D055728:Primary Myelofibrosis / Q000175:diagnosis* / Q000188:drug therapy; D013156:Splenectomy
chemical_list: D006918:Hydroxyurea