Stress spikes of hyperprolactinaemia and infertility.
Using couples with unexplained infertility as clinical models, a sub-group of approximately one-third separate out with high stress profile scores and intermittent mild elevations of prolactin 'spikers'. Pregnancy rates in such women when treated with a combination of clomiphene citrate and bromocriptine are found to be significantly more successful than placebo.
Harrison
R F
RF
Trinity College Department of Obstetrics and Gynaecology, St James's Hospital, Dublin, Ireland.
D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use; D002996:Clomiphene / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000209:etiology*; D007247:Infertility, Female / Q000188:drug therapy / Q000209:etiology*; D013312:Stress, Physiological / Q000150:complications*
D002996:Clomiphene; D001971:Bromocriptine