title: [Pathohistological characteristics of vaginal candidiasis in women of reproductive age].
abstract: Histological changes of vaginal mucosa and portio vaginalis are described in women of reproductive age suffering from candidosis. The epithelial surface is covered with adherent masses composed of desquamated and destroyed epithelial cells and leukocytes impregnated with proteins and penetrated by pseudomycelium. The outer epithelial layers are characterized by dystrophic and necrobiotic changes, desquamation, formation of fissures and small cavities. Pseudomycelium penetrates 4 to 6 layers of the epithelium. The barrier between the invading pathogen and the blood vessels of the lamina propria papillae in some sites is only 5-6 flattened epithelial cells thick. In the basal layer, high mitotic activity is noted. Lamina propria contains lympho-plasmocytic infiltrates.
authors: V L
authors: VL
authors: Bykov
mesh_terms: D000328:Adult; D002181:Candidiasis, Vulvovaginal / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008938:Mitosis; D009092:Mucous Membrane; D014621:Vagina / Q000473:pathology*
vernacular_title: Patogistologicheskaia kharakteristika kandidioza vlagalishcha u zhenshchin reproduktivnogo vozrasta.