A comparative study of frusemide-amiloride and cyclopenthiazide-potassium chloride in the treatment of congestive cardiac failure in general practice.
Forty-seven patients entered this comparison of frusemide-amiloride and cyclopenthiazide-potassium chloride in the treatment of congestive cardiac failure in general practice. Frusemide-amiloride was 'very satisfactory' in 92% of the patients compared to only 55% who took cyclopenthiazide-potassium chloride. Significantly more patients were free of paroxysmal nocturnal dyspnoea and orthopnoea after taking frusemide-amiloride.
Crawford
R J
RJ
Rorer Health Care Ltd, St Leonards House, Eastbourne, UK.
Allman
S
S
Gibson
W
W
Kitchen
S
S
Richards
H H
HH
D000584:Amiloride / Q000008:administration & dosage / Q000627:therapeutic use*; D003518:Cyclopenthiazide / Q000008:administration & dosage / Q000627:therapeutic use*; D004232:Diuretics; D004338:Drug Combinations; D004341:Drug Evaluation; D004417:Dyspnea / Q000188:drug therapy / Q000209:etiology; D004487:Edema / Q000188:drug therapy / Q000209:etiology; D005260:Female; D005665:Furosemide / Q000008:administration & dosage / Q000627:therapeutic use*; D006333:Heart Failure / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D011189:Potassium Chloride / Q000008:administration & dosage / Q000627:therapeutic use*; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use*
D004232:Diuretics; D004338:Drug Combinations; D049993:Sodium Chloride Symporter Inhibitors; D011189:Potassium Chloride; D000584:Amiloride; D005665:Furosemide; D011188:Potassium; D003518:Cyclopenthiazide