Aniridia with congenital ptosis and glaucoma: a family study.
In a family pedigree of aniridics, including eight patients from four generations, a wide range of ophthalmic anomalies was found. Varying degrees of congenital ptosis with decreased levator function were noted. All patients had corneal dystrophic changes. Three patients had congenital glaucoma, and one had acquired glaucoma. All affected family members except those with congenital glaucoma had microcornea. An infant with congenital glaucoma had a normal corneal diameter with an increased axial length.
Cohen
S M
SM
Pediatric Ophthalmology Service, Wills Eye Hospital, Philadelphia, PA 19107.
Nelson
L B
LB
D000328:Adult; D000368:Aged; D001763:Blepharoptosis / Q000151:congenital* / Q000235:genetics / Q000473:pathology; D002675:Child, Preschool; D003315:Cornea / Q000002:abnormalities / Q000473:pathology; D003316:Corneal Diseases / Q000150:complications / Q000473:pathology; D003318:Corneal Opacity / Q000150:complications / Q000473:pathology; D005260:Female; D005901:Glaucoma / Q000151:congenital* / Q000235:genetics; D006801:Humans; D007498:Iris / Q000002:abnormalities* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010375:Pedigree