title: Pregnancy and multiple sclerosis.
abstract: The effect of pregnancy on the relapse rate of multiple sclerosis has been investigated. Obstetric and relapse histories of 52 women with clinically definite multiple sclerosis were obtained; there were 101 pregnancies of which 85 were at risk of a multiple sclerosis relapse. By comparing the number of relapses in the pregnancy period (9 months of pregnancy and 6 months immediately post partum) with the number in non-pregnancy periods for the same women, no increased risk of relapse during the pregnancy period was demonstrated. However, of the relapses that did occur during the pregnancy period, there was a significant reduction in the number of relapses in the first and second trimesters.
authors: Department of Medicine, University of Sydney, N.S.W., Australia.
authors: J A
authors: JA
authors: Frith
authors: J G
authors: JG
authors: McLeod
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000503:physiopathology*; D009420:Nervous System / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011256:Pregnancy Outcome; D011644:Puerperal Disorders / Q000503:physiopathology; D012008:Recurrence