Short communication: deletion 7q, trisomy 6 and 11 in a case of Merkel-cell carcinoma.
Chromosome analysis of a metastatic Merkel-cell carcinoma established as xenografted tumor line in nude mice was performed. The analyzed karyotypes showed a stable cytogenetic feature characterized by trisomy 6 and 11 and a partial deletion of the long arm of chromosome #7 with the breakpoint localized at q31.2.
Sandbrink
F
F
Institute of Pathology, Hannover Medical School, Federal Republic of Germany.
Müller
L
L
Fiebig
H H
HH
Kovacs
G
G
D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D000368:Aged; D000818:Animals; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002880:Chromosomes, Human, Pair 11; D002896:Chromosomes, Human, Pair 6; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D007621:Karyotyping; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D014314:Trisomy; D014407:Tumor Cells, Cultured