[Mechanism of Felty's syndrome and long-term course].
The authors report 18 cases of Felty's syndrome followed, in an average, for 5 years (1 to 12 years). There were 3 deaths, 9 patients are in complete remission, 6 others still show signs of the disease: splenomegaly (4 cases), leucopenia (1 case) and only one complete Felty's syndrome. Steroid therapy has proved to be effective regardless of the mechanism of the neutropenia specified in 9 cases by an isotopic study. Prognosis and infectious risk are difficult to determine but the overall course was rather favorable.
Feldmann
J L
JL
Service de Rhumatologie et de Réadaptation Fonctionnelle, Centre Hospitalier, Argenteuil.
Menkès
C J
CJ
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D005258:Felty Syndrome / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000503:physiopathology; D011379:Prognosis; D013997:Time Factors
Mécanisme du syndrome de Felty et évolution à long terme.