title: Effects of increased cardiac output on pulmonary blood flow distribution during lobar ventilation hypoxia and collapse.
abstract: Electromagnetic flow probes were placed around the pulmonary artery and left lower lobe artery in anaesthetized open-chest dogs in order to measure possible changes in the ratio of lobar-to-total pulmonary blood flow (Ql/Qt) in response to changes in cardiac output produced by the opening of arterio-venous fistulae or fluid loading. Ventilation of the lobe with 7% oxygen or lobar collapse reduced Ql/Qt by 35% and 42%, respectively, but there were no significant changes in Ql/Qt in response to increases in Qt of 29-133%. It is concluded that the changes in Qt, pulmonary vascular pressures and mixed venous PO2 within the range studied did not influence Ql/Qt.
authors: Nuffield Department of Anaesthetics, Radcliffe Infirmary, Oxford.
authors: D
authors: D
authors: Cannon
authors: E J
authors: EJ
authors: Kalso
authors: H
authors: H
authors: Burchardi
authors: M K
authors: MK
authors: Sykes
mesh_terms: D000818:Animals; D002302:Cardiac Output; D004285:Dogs; D005260:Female; D008297:Male; D010100:Oxygen / Q000502:physiology*; D001261:Pulmonary Atelectasis / Q000503:physiopathology*; D011652:Pulmonary Circulation; D012039:Regional Blood Flow
chemical_list: D010100:Oxygen