Effects on the partial reinforcement extinction effect and on physical and reflex development of short-term in utero exposure to ethanol at different periods of gestation.
Ethanol was intubated into pregnant rats at Gestational Days 7-9 (G7-9) or 14-16 (G14-16). At both gestational ages, ethanol intubation affected reflex development but not physical development of resulting offspring. At G14-16, but not at G7-9, ethanol intubation resulted in the elimination of the partial reinforcement extinction effect when pups were tested at 15 days of age. These latter results confirm and extend previous ones in which ethanol was administered in a liquid diet throughout gestation.
Wigal
T
T
University of Texas, Department of Psychology, Austin 78712.
Greene
P L
PL
Amsel
A
A
D000818:Animals; D003213:Conditioning, Psychological / Q000187:drug effects*; D005314:Embryonic and Fetal Development; D000431:Ethanol / Q000494:pharmacology*; D005108:Extinction, Psychological; D005260:Female; D005333:Fetus / Q000187:drug effects*; D005865:Gestational Age; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D012018:Reflex / Q000187:drug effects*; D012055:Reinforcement Schedule
D000431:Ethanol