Computed tomography in the diagnosis of canine hyperadrenocorticism not suppressible by dexamethasone.
Computed tomography (CT) was performed in 10 dogs with hyperadrenocorticism not suppressible by dexamethasone. In 6 of these dogs, a unilateral adrenal mass was found on CT images. Specimens of the masses were obtained via retroperitoneal laparotomy; histologic examination revealed 4 carcinomas, 1 adenoma, and 1 nodular hyperplasia. In the 4 other dogs, CT revealed symmetric bilateral adrenal gland enlargement. In 2 of these dogs, contrast-enhanced CT revealed a mass in the pituitary fossa, which could be identified at necropsy as a pituitary tumor. The other 2 dogs were successfully treated with mitotane.
Voorhout
G
G
Department of Veterinary Radiology, Faculty of Veterinary Medicine, State University of Utrecht, The Netherlands.
Stolp
R
R
Lubberink
A A
AA
van Waes
P F
PF
D000304:Adrenal Cortex Function Tests / Q000662:veterinary*; D000308:Adrenocortical Hyperfunction / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000662:veterinary*; D000818:Animals; D003907:Dexamethasone; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004285:Dogs; D005260:Female; D008297:Male; D010912:Pituitary-Adrenal Function Tests / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000662:veterinary*
D003907:Dexamethasone