title: Modulation of GABA-stimulated chloride influx by beta-carbolines in rat brain membrane vesicles.
abstract: We have shown that GABA-stimulated chloride influx into membrane vesicles from the rat cerebral cortex can be enhanced or inhibited by beta-carbolines. The beta-carbolines can produce a full spectrum of responses from maximal enhancement to maximal inhibition.
authors: Department of Pharmacology, University of Arizona Health Sciences Center, Tucson 85721.
authors: E
authors: E
authors: Malatynska
authors: M
authors: M
authors: Serra
authors: M
authors: M
authors: Ikeda
authors: G
authors: G
authors: Biggio
authors: H I
authors: HI
authors: Yamamura
mesh_terms: D000818:Animals; D002243:Carbolines / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism*; D007700:Kinetics; D051381:Rats; D013329:Structure-Activity Relationship; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
chemical_list: D002243:Carbolines; D002712:Chlorides; D005680:gamma-Aminobutyric Acid