Long-term results of balloon pulmonary valvuloplasty of valvar pulmonic stenosis.
The purpose of this paper is to document long-term results of percutaneous balloon pulmonary valvuloplasty. Forty-one patients, aged 7 days to 20 years, underwent pulmonary valvuloplasty over a 3 1/2-year period ending in April, 1987. Balloon valvuloplasty resulted in immediate reduction in the pulmonary valvar pressure gradient from 92 +/- 45 to 30 +/- 22 mm Hg (p less than 0.001). Follow-up (3 to 34 months) clinical, ECG, and echo Doppler data were available in 35 patients. Follow-up (6 to 34 months) cardiac catheterization data were available in 29 of the 35 patients. Short ejection systolic murmurs were heard in all 35, but an early diastolic decrescendo murmur was heard in only 12 patients. Based on the catheterization and Doppler data, the patients were divided into two groups: group I (30 patients) with excellent results and group II (five patients) with poor results (gradients greater than 50 mm Hg). In group I ECG right ventricular hypertrophy regressed. The echocardiographic right ventricular end-diastolic dimension (21 +/- 6 vs 15.9 +/- 4.6 mm) decreased (p less than 0.001) while the left ventricular dimension increased (p less than 0.02). Peak Doppler flow velocity in the main pulmonary artery fell from 4.0 +/- 0.8 m/sec to 2.3 +/- 0.5 m/sec (p less than 0.001). Doppler evidence for pulmonary insufficiency was present in 21 patients. Catheterization-determined pulmonary valvar gradients (24 patients) also fell from 95.6 +/- 50.3 mm Hg to 18.3 +/- 12.5 mm Hg (p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
Rao
P S
PS
Department of Pediatrics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Fawzy
M E
ME
Solymar
L
L
Mardini
M K
MK
D000293:Adolescent; D000328:Adult; D001783:Blood Flow Velocity; D002404:Catheterization; D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011666:Pulmonary Valve Stenosis / Q000503:physiopathology / Q000628:therapy*; D012008:Recurrence