title: Magnetic field associated with spreading depression: a model for the detection of migraine.
abstract: Slow variations of the magnetic field were recorded in real time during spreading depression (SD) in the isolated turtle cerebellum. The magnetic signal lasted for 2-10 min with the largest amplitude in the first minute. The field strength was of sufficient magnitude to be measured unaveraged at 2-4 cm from the tissue. The directions and time course of the magnetic signal indicated that cerebellar SD is accompanied by current normal to the cerebellar surface. The observations reported here are of clinical interest due to the potential involvement of SD in various neurological disorders, notably head trauma and migraine.
authors: Department of Physiology and Biophysics, New York University Medical Center, NY 10016.
authors: Y C
authors: YC
authors: Okada
authors: M
authors: M
authors: Lauritzen
authors: C
authors: C
authors: Nicholson
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000503:physiopathology*; D013181:Cortical Spreading Depression; D004195:Disease Models, Animal; D004569:Electroencephalography; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D066298:In Vitro Techniques; D008881:Migraine Disorders / Q000503:physiopathology*; D014426:Turtles