title: Cognitive, behavioral, and adaptive functioning in fragile X and non-fragile X retarded men.
abstract: The cognitive, behavioral, and adaptive functioning of 12 men with fragile X syndrome (aged 23 to 62 years) was systematically assessed and compared to two matched groups of retarded men without fragile X syndrome residing at the same institution. The fragile X group was largely indistinguishable from the comparison groups on the cognitive, behavioral, and adaptive measures. Fragile X patients were, however, significantly more likely to have achieved levels of adaptive functioning commensurate with their intellectual abilities. Fragile X subjects who had similarly affected siblings emerged as significantly higher-functioning in all areas than Fragile X subjects who did not have affected siblings. These findings are discussed with respect to future research.
authors: Yale University School of Medicine, New Haven, Connecticut.
authors: E
authors: E
authors: Dykens
authors: J
authors: J
authors: Leckman
authors: R
authors: R
authors: Paul
authors: M
authors: M
authors: Watson
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D003072:Cognition Disorders / Q000235:genetics*; D005600:Fragile X Syndrome / Q000150:complications / Q000523:psychology*; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics* / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012729:Sex Chromosome Aberrations / Q000523:psychology*