title: Human placenta gangliosides.
abstract: Gangliosides extracted from human placenta were composed of four major components (G1-G4), which were purified by silica beads column chromatography. The structures of these gangliosides were analyzed by exoglycosidase treatments, 400 MHz proton magnetic resonance spectroscopy and gas chromatography-mass spectrometry and were concluded to be as follows: (Formula: see text). Gangliosides containing more than 10 sugar residues were observed in addition to the above four major components. But ganglio-series gangliosides were undetectable in the placenta.
authors: Department of Biochemistry, Shizuoka College of Pharmacy, Japan.
authors: T
authors: T
authors: Taki
authors: K
authors: K
authors: Matsuo
authors: K
authors: K
authors: Yamamoto
authors: T
authors: T
authors: Matsubara
authors: A
authors: A
authors: Hayashi
authors: T
authors: T
authors: Abe
authors: M
authors: M
authors: Matsumoto
mesh_terms: D000606:Amino Sugars / Q000032:analysis; D001789:Blood Group Antigens / Q000032:analysis; D002240:Carbohydrate Sequence; D005260:Female; D005732:Gangliosides / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006026:Glycoside Hydrolases / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010920:Placenta / Q000032:analysis*; D011247:Pregnancy
chemical_list: D000606:Amino Sugars; D001789:Blood Group Antigens; D005732:Gangliosides; C032233:lactosamine; D006026:Glycoside Hydrolases