title: The treatment of normospermic infertility by gamete intrafallopian transfer (GIFT).
abstract: Gamete intrafallopian transfer (GIFT) was applied in 207 treatment cycles in 73 couples. The pregnancy rate in cycles with only one (2/21, 9.5%) or two (2/29, 6.9%) oocytes transferred was significantly less than that in which four oocytes (36/116, 31.0%) were replaced. The collection of more than four oocytes did not influence the pregnancy rate in that treatment cycle. The overall pregnancy rate was 24.2% (50 of 207) and was similar in the four infertility groups studied (non-occlusive tubal disorders, endometriosis, cervical factor and unexplained infertility) with 28 (56%) of the pregnancies delivered at greater than or equal to 20 weeks. The pregnancy wastage included 4 (8%) ectopic pregnancies and 3 (6%) late pregnancy losses. The 12 multiple pregnancies occurred following the transfer of three and four oocytes.
authors: PIVET Medical Centre, Leederville, Perth, Western Australia.
authors: J L
authors: JL
authors: Yovich
authors: P L
authors: PL
authors: Matson
authors: D G
authors: DG
authors: Blackledge
authors: S R
authors: SR
authors: Turner
authors: P A
authors: PA
authors: Richardson
authors: J M
authors: JM
authors: Yovich
authors: W R
authors: WR
authors: Edirisinghe
mesh_terms: D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007315:Insemination, Artificial / Q000379:methods*; D007317:Insemination, Artificial, Homologous / Q000379:methods*; D010063:Ovum / Q000637:transplantation*; D011247:Pregnancy