[Effect of adrenaline on the succinate dehydrogenase activity of peripheral blood lymphocytes of rats following exposure to ionizing radiation].
In experiments with albino mongrel female rats, the influence of adrenaline on succinate dehydrogenase (SDG) activity in the peripheral blood lymphocytes of irradiated and intact animals has been investigated. Two minutes after the intraperitoneal administration of adrenaline (1 mg/kg) to intact rats SDG activity sharply rises and 3-4 min it drastically falls. In 6 to 8 min the second peak in the enzyme activity is registered. Twenty minutes after irradiation of rats in the cranio-caudal direction with a dose of 75 Gy delivered to head, the reaction to adrenaline, manifested by the rise in SDG activity, is absent.
Koroleva
L V
LV
Vasin
M V
MV
D000818:Animals; D003037:Cobalt Radioisotopes; D004837:Epinephrine / Q000494:pharmacology*; D005260:Female; D005720:Gamma Rays; D008214:Lymphocytes / Q000187:drug effects / Q000201:enzymology / Q000528:radiation effects*; D051381:Rats; D013385:Succinate Dehydrogenase / Q000097:blood*
D003037:Cobalt Radioisotopes; D013385:Succinate Dehydrogenase; D004837:Epinephrine
Vliianie adrenalina na aktivnost' suktsinatdegidrogenazy v limfotsitakh perifericheskoĭ krovi krys posle vozdeĭstviia ioniziruiushchego izlucheniia.