title: Bowen's disease and internal malignant diseases. A study of 581 patients.
abstract: In a retrospective study of 581 patients with a diagnosis of Bowen's disease (BD) treated over a 40-year period, we traced patient records to identify later diagnoses of nonskin cancer. Fifty patients had nonskin cancer, as against an expected number of 40, but this difference was not significant. The lack of association was equally true for BD on sun-exposed and non-sun-exposed skin. Our findings support the view that BD is not a skin marker for internal malignant disease.
authors: Department of Dermatology, Finsen Institute, Copenhagen, Denmark.
authors: F
authors: F
authors: Reymann
authors: L
authors: L
authors: Ravnborg
authors: G
authors: G
authors: Schou
authors: G
authors: G
authors: Engholm
authors: A
authors: A
authors: Osterlind
authors: K
authors: K
authors: Thestrup-Pedersen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001913:Bowen's Disease / Q000150:complications*; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D003718:Denmark; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000453:epidemiology; D012042:Registries; D012737:Sex Factors; D012878:Skin Neoplasms / Q000150:complications*