Favorable outcome after treatment with amantadine and ribavirin in a pregnancy complicated by influenza pneumonia. A case report.
The moderate impairment of cell-mediated immunity that occurs in pregnancy justifies concern when a pregnant woman develops influenza. We treated a woman for influenza pneumonia with respiratory failure at 33 weeks' gestation with oral amantadine and ribavirin inhalation therapy in conjunction with evacuation of the uterus and delivery.
Kirshon
B
B
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030.
Faro
S
S
Zurawin
R K
RK
Samo
T C
TC
Carpenter
R J
RJ
D000328:Adult; D000547:Amantadine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009980:Influenza A virus / Q000302:isolation & purification; D007251:Influenza, Human / Q000188:drug therapy*; D011024:Pneumonia, Viral / Q000188:drug therapy*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D011256:Pregnancy Outcome; D012254:Ribavirin / Q000627:therapeutic use*; D012263:Ribonucleosides / Q000627:therapeutic use*
D012263:Ribonucleosides; D012254:Ribavirin; D000547:Amantadine