Successful pregnancy in an ovulating recipient following the transfer of two frozen-thawed embryos obtained from anonymously donated oocytes.
A fertile woman suffering from mild dystrophia myotonica had undergone sterilization because of the 50% genetic risk of this disease developing in her offspring. In her second treatment cycle on the donor oocyte program, four anonymously donated oocytes were inseminated with frozen-thawed sperm of her husband. Three embryos were obtained and two surviving embryos were deep-frozen at the eight-cell stage and kept in storage for 9 months. These embryos were successfully thawed and transferred to the recipient 97 hr after the onset of her luteinizing hormone surge. A normal singleton pregnancy developed and a healthy male infant was delivered by cesarean section at 36 weeks of gestation.
Leeton
J
J
Monash-Epworth in Vitro Fertilization Program, Epworth Hospital, Richmond, Victoria, Australia.
Freemann
L
L
King
C
C
Brady
T
T
Cameron
I
I
Harman
J
J
D000328:Adult; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D005615:Freezing; D006801:Humans; D009865:Oocytes / Q000637:transplantation*; D010060:Ovulation; D011247:Pregnancy / Q000502:physiology*; D011309:Preservation, Biological / Q000379:methods*