Experimental exposure to alcohol as a model for the evaluation of neurobehavioural tests.
The performance characteristics of 4 computerized psychological tests were studied using alcohol as a model compound. Subjects received alcohol (0.5 ml/kg) or placebo in a cross-over design and performance was assessed using the Simple Reaction Time test, the Switching Attention test, the Hand/Eye Coordination test and the Color-Word Vigilance test. Analyses indicated an overall significant effect of alcohol at blood-alcohol levels of 0.03% with response speed on the Color-Word Vigilance test being the most sensitive parameter.
Hooisma
J
J
Medical Biological Laboratory TNO, Rijswijk, The Netherlands.
Twisk
D A
DA
Platälla
S
S
Muijser
H
H
Kulig
B M
BM
D000328:Adult; D000704:Analysis of Variance; D000431:Ethanol / Q000097:blood / Q000633:toxicity*; D006801:Humans; D008297:Male; D011597:Psychomotor Performance / Q000187:drug effects*; D012984:Software
D000431:Ethanol