title: Sustained pressurization of polymethylmethacrylate: a comparison of low- and moderate-viscosity bone cements.
abstract: There is at present great uncertainty relating to the fixation of joint implants. The deficiencies of acrylic bone cement are well documented, but the limitations of cementless fixation are as yet imcompletely identified. The purpose of this study was to investigate the potential of sustained external pressurization to improve the mechanical characteristics of conventional acrylic bone cement. The effect of serially increasing sustained pressurization of two commerically available acrylic bone cements (Simplex-P and LVC) was evaluated in human cadaver femora. A new method for determination of the shear strength of the bone-cement interface in place of the traditional pushout tests was used. In this model, there was a significant increase in the bone-cement interfacial shear strength with increasing pressure, but no difference in the shear strength was found between the two cements. At all pressure levels, the shear strength of the cement was greater than that previously reported. Increased cement penetration into the cortical bone was demonstrated with increasing pressure and low-viscosity cement, but the extent of cement penetration did not correlate with the shear strength of the bone-cement interface.
authors: Division of Orthopaedics and Rehabilitation, University of California, San Diego.
authors: D J
authors: DJ
authors: Bean
authors: J M
authors: JM
authors: Hollis
authors: S L
authors: SL
authors: Woo
authors: F R
authors: FR
authors: Convery
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001696:Biomechanical Phenomena; D001843:Bone Cements; D005260:Female; D005269:Femur; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008768:Methylmethacrylates; D008875:Middle Aged; D011312:Pressure; D013314:Stress, Mechanical; D014783:Viscosity
chemical_list: D001843:Bone Cements; D008768:Methylmethacrylates