Massive striatal dopamine release in acute cerebral ischemia in rats.
Extracellular dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and cerebral blood flow were simultaneously determined using in vivo brain dialysis and a hydrogen clearance method in the striatum of spontaneously hypertensive rats during ischemia and after recirculation. Massive striatal dopamine release was demonstrated in acutely induced ischemic brain.
Yao
H
H
The Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Sadoshima
S
S
Ishitsuka
T
T
Nagao
T
T
Fujishima
M
M
Tsutsumi
T
T
Uchimura
H
H
D015102:3,4-Dihydroxyphenylacetic Acid / Q000378:metabolism; D000818:Animals; D002339:Carotid Arteries; D002560:Cerebrovascular Circulation; D003342:Corpus Striatum / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism*; D002546:Ischemic Attack, Transient / Q000503:physiopathology*; D008026:Ligation; D051381:Rats; D011918:Rats, Inbred SHR
D015102:3,4-Dihydroxyphenylacetic Acid; D004298:Dopamine