title: [Electrophysiological characteristics of cardiac function and the intensity of protein synthesis in cardiomyocytes during the arousal of susliks from hibernation].
abstract: It has been demonstrated that during winter hibernation (body temperature 2-4 degrees C), the heart rate in ground squirrels is equal to 100 10-12 beats/min. At the initial stage of the arousal, while body temperature remains still low (9-10 degrees C), the heart rate may increase up to 160-200 beats/min. At this stage, practically all electrophysiological parameters of the heart correspond to those in active animals. These results may indicate the ability of "cold" heart in arousing ground squirrels to operate as a normothermic organ and reveal certain role of the heart in body warming. Significant increase of the intensity of protein synthesis in cardiomyocytes together with periodic changes in protein composition of their membranes were found during arousal which may account for regulation of the level of metabolism in cells and for adaptation of the latter to different temperatures.
authors: G F
authors: GF
authors: Zhegunov
mesh_terms: D000818:Animals; D001143:Arousal / Q000502:physiology*; D001831:Body Temperature; D002250:Carbon Radioisotopes; D004562:Electrocardiography; D004594:Electrophysiology; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D006605:Hibernation; D009206:Myocardium / Q000378:metabolism*; D014176:Protein Biosynthesis; D051381:Rats; D012589:Sciuridae / Q000502:physiology*
chemical_list: D002250:Carbon Radioisotopes
vernacular_title: Elektrofiziologicheskie kharakteristiki funktsionirovaniia serdtsa i intensivnost' sinteza belkov kardiomiotsitov pri probuzhdenii suslikov ot zimneĭ spiachki.