title: Amino-acid sequences of four cytotoxins (cytotoxins I, II, III and IV) purified from the venom of the Thailand cobra, Naja naja siamensis.
abstract: Four cytotoxins, designated as cytotoxins I, II, III and IV, were isolated from the venom of the Thailand cobra (Naja naja siamensis) by gel filtration on Sephadex G-75 followed by CM-cellulose chromatography. The amino-acid sequences were determined by a combination of conventional methods. Cytotoxins I, II, III and IV were each composed of 60 amino-acid residues and their molecular weights were calculated to be 6693, 6646, 6709 and 6739, respectively. The amino-acid sequences were compared with those of cytotoxins from other cobra venoms already sequenced.
authors: Department of Biochemistry, Osaka University of Pharmaceutical Sciences, Japan.
authors: K
authors: K
authors: Ohkura
authors: S
authors: S
authors: Inoue
authors: K
authors: K
authors: Ikeda
authors: K
authors: K
authors: Hayashi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003603:Cytotoxins / Q000235:genetics* / Q000302:isolation & purification; D004546:Elapid Venoms / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D013045:Species Specificity
chemical_list: D003603:Cytotoxins; D004546:Elapid Venoms; C037375:cobra cytotoxin I; C045369:cobra cytotoxin II; C055953:cobra cytotoxin III; C055954:cobra cytotoxin IV