title: [Dynamic contrast medium studies with flash sequences in nuclear magnetic resonance tomography of the breast].
abstract: In this study the dynamic contrast behavior after Gd-DTPA of different breast tissues and tumors has been investigated with a series of T1-weighted FLASH-sequences during the first 5 minutes after the application of Gd-DTPA. The results of these dynamic FLASH-measurements have been compared to the results of the SE-sequences 6-10 and 11-15 minutes after Gd-DTPA in 40 patients with 54 different breast tissues. It could be shown that in a number of cases a better differentiation (e.g. DD between carcinomas and proliferative dysplasia) was possible on FLASH-scans early after contrast medium than on the late SE-scans. Only the distinction between non-proliferative and proliferative dysplasia was better on the late SE-scans. Evaluation of the enhancement dynamics may be helpful in some cases as an additional information. Further investigations are necessary to confirm these findings and to assess their value.
authors: Radiologische Klinik, Klinikums Grosshadern, Universität München.
authors: S H
authors: SH
authors: Heywang
authors: T
authors: T
authors: Hilbertz
authors: E
authors: E
authors: Pruss
authors: A
authors: A
authors: Wolf
authors: W
authors: W
authors: Permanetter
authors: W
authors: W
authors: Eiermann
authors: J
authors: J
authors: Lissner
mesh_terms: D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000473:pathology*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000473:pathology; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
vernacular_title: Dynamische Kontrastmitteluntersuchungen mit FLASH bei Kernspintomographie der Mamma.