title: Effect of pectic substances on prolactin and growth hormone secretion in the ewe and on the induction of casein synthesis in the rat.
abstract: Pectins from apple, citrus and sugar beet injected intravenously to ewes markedly stimulated blood prolactin, growth hormone (GH) and cortisol. Pectic acid and polygalacturonic acid exhibited the same property. A preparation of oligogalacturonic acid with a polymerisation degree of 12 to 13 was also active, whereas oligomers with a smaller degree of polymerisation (congruent to 10) were devoid of activity. Pectic acid administered orally to mature virgin rats induced the accumulation of beta-casein in mammary gland. Pectins and some of their derivatives therefore had a lactogenic property and their effect probably resulted from a capacity to trigger lactogenic hormone secretion.
authors: Laboratoire de Physiologie de la Lactation, I.N.R.A., Jouy-en-Josas, France.
authors: L
authors: L
authors: Sawadogo
authors: L M
authors: LM
authors: Houdebine
authors: J F
authors: JF
authors: Thibault
authors: X
authors: X
authors: Rouau
authors: M
authors: M
authors: Ollivier-Bousquet
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002364:Caseins / Q000096:biosynthesis*; D005260:Female; D013006:Growth Hormone / Q000378:metabolism*; D006854:Hydrocortisone / Q000378:metabolism*; D007275:Injections, Intravenous; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000378:metabolism; D010368:Pectins / Q000008:administration & dosage / Q000494:pharmacology*; D011388:Prolactin / Q000378:metabolism*; D051381:Rats; D012756:Sheep
chemical_list: D002364:Caseins; D010368:Pectins; D011388:Prolactin; D013006:Growth Hormone; C003181:polygalacturonic acid; D006854:Hydrocortisone