Serological screening of cord blood for syphilis.
Meticulous antenatal screening for maternal syphilis can prevent congenital syphilis. In the event of inadequate antenatal screening, determination of reagin reactivity on cord blood becomes mandatory. A card test utilising the VDR carbon antigen (Wellcome) was used to screen cord blood samples for reagin reactivity. The same blood was also screened by a reference laboratory, where the VDRL card test was repeated and every result was substantiated by treponemal tests. The VDRL card test done at the local laboratory had a sensitivity of 83,3% and a specificity of 99,8% when compared with the results of the reference laboratory.
Delport
S D
SD
Department of Paediatrics, University of Pretoria.
D005069:Evaluation Studies as Topic; D005312:Fetal Blood / Q000276:immunology*; D006801:Humans; D007231:Infant, Newborn; D011935:Reagins / Q000032:analysis; D013588:Syphilis Serodiagnosis / Q000379:methods*; D013590:Syphilis, Congenital / Q000175:diagnosis*
D011935:Reagins