Distribution of estrogen receptors in the rat pituitary as studied by in situ hybridization.
The localization of estrogen receptors in the rat pituitary gland was performed by in situ hybridization. The probe used was a synthetic oligonucleotide probe labelled with 35S complementary to the mRNA coding for a fragment (1-24) of estrogen receptor. Strong labelling was observed in cells of the anterior and intermediate lobes whereas the posterior lobe remains unlabelled. These results suggest that not only the anterior lobe but also the intermediate lobe is a target for estrogens.
Pelletier
G
G
MRC Group in Molecular Endocrinology, Le Centre Hospitalier de l'Université Laval, Quebec, Que, Canada.
Liao
N
N
Follea
N
N
Govindan
M V
MV
D000818:Animals; D005260:Female; D009693:Nucleic Acid Hybridization; D010903:Pituitary Gland, Anterior / Q000032:analysis*; D012333:RNA, Messenger / Q000032:analysis* / Q000235:genetics; D051381:Rats; D011960:Receptors, Estrogen / Q000032:analysis*
D012333:RNA, Messenger; D011960:Receptors, Estrogen