title: [Effect of cyanamide on the level of endogenous ethanol in the liver of normal rats and in hypocorticism].
abstract: The rat liver endogenous ethanol level was found to increase under inhibition of aldehyde dehydrogenases by cyanamide. Adrenalectomy results in a decrease of the liver endogenous ethanol content and abolishes cyanamide effect on this index. One of the mechanisms of cyanamide toxic effect may be accumulation of different aldehydes including acetaldehyde.
authors: Iu A
authors: IuA
authors: Tarasov
authors: V I
authors: VI
authors: Satanovskaia
authors: S N
authors: SN
authors: Shishkin
authors: Iu M
authors: IuM
authors: Ostrovskiĭ
mesh_terms: D000079:Acetaldehyde / Q000378:metabolism; D000309:Adrenal Insufficiency / Q000201:enzymology*; D000315:Adrenalectomy; D000426:Alcohol Dehydrogenase / Q000378:metabolism; D000444:Aldehyde Dehydrogenase / Q000378:metabolism; D000818:Animals; D003484:Cyanamide / Q000494:pharmacology*; D003486:Cyanides / Q000494:pharmacology*; D000431:Ethanol / Q000378:metabolism*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D051381:Rats; D013997:Time Factors
chemical_list: D003486:Cyanides; D000431:Ethanol; D003484:Cyanamide; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase; D000079:Acetaldehyde
vernacular_title: Vliianie tsianamida na uroven' éndogennogo étanola v pecheni krys v norme i pri gipokortitsizme.