[Action of beta-adrenomimetics on the degree of lysosomal membrane damage and glycogen phosphorylase activity of the ventricular myocardium of guinea pigs].
The effects of partusisten, novodrin and nonachlazine on the acid phosphatase and glycogenphosphorylase activities in the guinea pig ventricle myocardium were studied. The injection of partusisten (1 mg/kg) significantly increased the acid phosphatase activity and preserved the strong negative correlation between the free activity of acid phosphatase seen in control animals and the "free activity/total activity" ratio. Beta adrenergic agonists exerted different effects on the "glycogenphosphorylase B activity/glycogenphosphorylase A + B activity" ratio.
Sysoliatina
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D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects*; D006352:Heart Ventricles / Q000187:drug effects / Q000201:enzymology; D007425:Intracellular Membranes / Q000187:drug effects* / Q000201:enzymology; D008247:Lysosomes / Q000187:drug effects* / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology*; D006005:Phosphorylases / Q000378:metabolism*; D013566:Sympathomimetics / Q000494:pharmacology*
D013566:Sympathomimetics; D006005:Phosphorylases; D000135:Acid Phosphatase
O deĭstvii beta-adrenomimetikov na stepen' povrezhdeniia lizosomal'nykh membran i glikogenfosforilaznuiu aktivnost' v miokarde zheludochkov morskikh svinok.