Bardet-Biedl and Laurence-Moon syndromes in a mixed Arab population.
In the Arab population of Kuwait of approximately 1.3 million, 26 cases in 15 families were ascertained to have Bardet-Biedl syndrome (20 cases in 13 families) or Laurence-Moon syndrome (6 cases in 2 families). The apparently increased frequency of these interrelated autosomal recessive syndromes in Arabs is discussed in view of the high consanguinity rate and large family size.
Farag
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Kuwait Medical Genetics Centre, Maternity Hospital.
Teebi
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D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D005260:Female; D005808:Genes, Recessive; D005837:Genitalia, Male / Q000002:abnormalities; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007730:Kuwait; D007849:Laurence-Moon Syndrome / Q000453:epidemiology / Q000235:genetics*; D008297:Male