title: [Clazuril: a new anticoccidial agent for pigeons].
abstract: The effectiveness of clazuril (Appertex), a new anticoccidial agent for the treatment of pigeons is described in the present study. Clazuril, a benzene-acetonitrile derivative, is administered in a single dose. In laboratory studies, 121 carrier pigeons infected with E. labbeana and E. columbarum were treated once with clazuril in gelatin capsules at dose levels of 10 mg, 5 mg, 2.5 mg, 1.25 mg, 0.63 mg or with a placebo. When a single dose of 2.5 mg and higher was administered, all faecal samples became negative for oocysts within seven days after treatment. In the field studies, 1531 young and full-grown carrier pigeons, from 116 infected dove-cotes, were treated with 1 tablet of 2.5 mg clazuril. Seven days after treatment, the faecal samples of 105 dove-cotes were negative for oocysts of E. Labbeana and E. columbarum; in six dove-cotes, infection was also virtually reduced to zero. Performance in racing was not affected by treatment and side-effects were not observed.
authors: Janssen Pharmaceutica, N.V., Beerse, België.
authors: O
authors: O
authors: Vanparijs
authors: L
authors: L
authors: Hermans
authors: L
authors: L
authors: Van der Flaes
authors: K
authors: K
authors: Vlaminck
authors: R
authors: R
authors: Marsboom
mesh_terms: D000097:Acetonitriles / Q000627:therapeutic use*; D000818:Animals; D001715:Bird Diseases / Q000188:drug therapy*; D001717:Birds; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003049:Coccidiostats / Q000627:therapeutic use*; D005260:Female; D008297:Male; D014227:Triazines / Q000627:therapeutic use*
chemical_list: D000097:Acetonitriles; D003049:Coccidiostats; D014227:Triazines; C056172:clazuril
vernacular_title: Clazuril: een nieuw anti-coccidiosemiddel voor duiven.