title: [Study of the Thomsen-Friedenreich antigen in bladder tumors].
abstract: Thomsen Friedenreich antigen (T-ag), ABH isoantigen (ABH-ag) in 106 cases with bladder tumor (all transitional cell carcinoma) of various histological grades and stages were investigated by the Avidin-Biotin-Peroxidase Complex (ABC) method. There was a correlation between histological grade, stage and deletion of the antigenicity (T-ag and ABH-ag). In a follow-up study of 45 patients with low grade and low stage tumor, the recurrence rate after surgery of the cases with abnormal antigenicity (T-ag and ABH-ag) was significantly higher than that of the cases with the normal antigenicity. Combination of two markers (T-ag and ABH-ag) was significantly more effective than the single marker.
authors: Department of Urology, Aichi Medical University.
authors: H
authors: H
authors: Fukatsu
authors: H
authors: H
authors: Yamada
authors: H
authors: H
authors: Nonomura
authors: Y
authors: Y
authors: Miyagawa
authors: M
authors: M
authors: Waki
authors: Y
authors: Y
authors: Hatano
authors: S
authors: S
authors: Hiraiwa
authors: T
authors: T
authors: Muramatsu
authors: E
authors: E
authors: Nishikawa
authors: Y
authors: Y
authors: Yamada
mesh_terms: D000017:ABO Blood-Group System / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor / Q000032:analysis; D002295:Carcinoma, Transitional Cell / Q000276:immunology*; D004187:Disaccharides / Q000032:analysis*; D006801:Humans; D001749:Urinary Bladder Neoplasms / Q000276:immunology*
chemical_list: D000017:ABO Blood-Group System; D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D004187:Disaccharides; C016467:Thomsen-Friedenreich antigen