title: PARA-SITE: a computer algorithm for rapidly analyzing the physical-chemical properties of amino acid sequences at sites of co- and post-translational protein processing.
abstract: A new algorithm is presented which can be used to examine the physical-chemical properties of amino acids at sites of co- or post-translational processing. This algorithm has been incorporated into a computer program known as PARA-SITE. Thirty different parameters can be studied for amino acids which occupy comparable positions in naturally occurring proteins. PARA-SITE should aid in the design and interpretation of protein engineering experiments which seek to dissect structure/activity relationships.
authors: Department of Biological Chemistry, Washington University School of Medicine, St Louis, MO 63110.
authors: R J
authors: RJ
authors: Folz
authors: J I
authors: JI
authors: Gordon
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D011487:Protein Conformation; D011499:Protein Processing, Post-Translational; D011506:Proteins / Q000378:metabolism; D012984:Software; D013329:Structure-Activity Relationship
chemical_list: D011506:Proteins