title: Strain-specific development of the mossy fiber system in organotypic cultures of the mouse hippocampus.
abstract: The postnatal development of the hippocampus of the inbred mice strains BALB/c, C57BL/6, and DBA/2 was studied in organotypic explant cultures using the roller-tube technique. In vivo, mice exhibit strain-specific mossy fiber distribution patterns. As a main result we found, that after cultivation of 3-4 weeks, similar strain-specific patterns became apparent in vitro, as visualized by a modified Timm staining. From this experiment we can conclude that a postnatal extrinsic influence cannot be the cause of the strain-specific hippocampal features.
authors: Institut für Humangenetik and Anthropologie, Universität Heidelberg, F.R.G.
authors: H
authors: H
authors: Schwegler
authors: B
authors: B
authors: Heimrich
authors: F
authors: F
authors: Keller
authors: P
authors: P
authors: Renner
authors: W E
authors: WE
authors: Crusio
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D006624:Hippocampus / Q000166:cytology* / Q000254:growth & development / Q000502:physiology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains / Q000254:growth & development*; D009473:Neuronal Plasticity; D013045:Species Specificity