Chromosome sublocalization of a cDNA for human DNA polymerase-beta to 8p11----p12.
We have localized a cDNA fragment that codes for human DNA polymerase-beta. Using somatic cell and in situ hybridization techniques, this cDNA was cloned by screening a human KM-3 cell cDNA library in lambda gt 11 for expression of fused beta-galactosidase-human DNA polymerase-beta proteins. We have mapped this human polymerase-beta gene to the short arm of chromosome 8 in the subregion 8p11----p12.
Cannizzaro
L A
LA
Genetics and Cancer Center, Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
Bollum
F J
FJ
Huebner
K
K
Croce
C M
CM
Cheung
L C
LC
Xu
X
X
Hecht
B K
BK
Hecht
F
F
Chang
L M
LM
D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002898:Chromosomes, Human, Pair 8; D004247:DNA / Q000235:genetics*; D004256:DNA Polymerase I / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D007621:Karyotyping; D051379:Mice; D009693:Nucleic Acid Hybridization
D004247:DNA; D004256:DNA Polymerase I