An analysis of the effect of the PMSG--HCG interval on the two-cell block.
The effect of increasing the interval between the administrations of pregnant mare's serum gonadotrophin and HCG to female mice from 48 to 60 h on the mating frequency, ovulation rate, fertilization rate and development through the two-cell stage has been investigated. It is concluded that use of the longer interval is of no advantage, and may be disadvantageous.
George
M A
MA
Department of Anatomy, Cambridge, UK.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000008:administration & dosage* / Q000494:pharmacology; D005314:Embryonic and Fetal Development; D005260:Female; D006064:Gonadotropins, Equine / Q000008:administration & dosage* / Q000494:pharmacology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009865:Oocytes / Q000187:drug effects / Q000254:growth & development*; D013997:Time Factors
D006063:Chorionic Gonadotropin; D006064:Gonadotropins, Equine