Human alpha 2-HS-glycoprotein localized to 3q27----q29 by in situ hybridization.
Human plasma protein alpha 2-HS-glycoprotein (AHSG) is composed of two polypeptide chains, A and B, encoded by a single mRNA. Southern blot analysis of mouse x human somatic cell hybrids has mapped the AHSG gene to human chromosome 3 in the region 3q21----qter (Lee et al., 1987). Using a recombinant plasmid containing a 1,538 bp insert spanning the entire AHSG coding region, AHSG was localized to chromosomal bands 3q27----q29 by in situ hybridization.
Magnuson
V L
VL
Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio 78284.
McCombs
J L
JL
Lee
C C
CC
Yang
F
F
Bowman
B H
BH
McGill
J R
JR
D001798:Blood Proteins / Q000235:genetics*; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3 / Q000648:ultrastructure; D004247:DNA / Q000235:genetics; D005796:Genes; D006801:Humans; D009693:Nucleic Acid Hybridization; D060749:alpha-2-HS-Glycoprotein
C556354:AHSG protein, human; C556357:Ahsg protein, mouse; D001798:Blood Proteins; D060749:alpha-2-HS-Glycoprotein; D004247:DNA