Gastric emptying of an indigestible solid in patients with end-stage renal disease on continuous ambulatory peritoneal dialysis.
Using radiopaque markers, we evaluated gastric emptying in 10 male patients with end-stage renal disease on continuous ambulatory peritoneal dialysis and in 15 normal men. Dialysis patients were studied twice, once without peritoneal dialysate in the abdomen (drained) and once with 2 L of dialysate in the abdomen (full). Each normal man and 9 of 10 dialysis patients, when drained, emptied all 10 markers by 6 h after a test meal. In contrast, 5 of the 10 dialysis patients, when full, had delayed emptying of radiopaque markers. Thus, continuous ambulatory dialysis may delay gastric emptying of indigestible solids.
Brown-Cartwright
D
D
Department of Internal Medicine, Dallas Veterans Administration Medical Center, Texas.
Smith
H J
HJ
Feldman
M
M
D000328:Adult; D004063:Digestion; D005746:Gastric Emptying; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000209:etiology / Q000503:physiopathology; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects; D014839:Vomiting / Q000209:etiology / Q000503:physiopathology