title: Oral urea in the treatment of secondary tumours in the liver.
abstract: Twenty patients with secondary liver tumours, predominantly from colorectal carcinoma, were treated with oral urea at a daily dose of 8 gm-2. Treatment was well tolerated without side-effects. No objective responses were seen. It is concluded that oral urea is ineffective in the treatment of liver metastases from colorectal cancer.
authors: Department of Medical Oncology, St. Bartholomew's Hospital, London, UK.
authors: P I
authors: PI
authors: Clark
authors: M L
authors: ML
authors: Slevin
authors: J A
authors: JA
authors: Webb
authors: R J
authors: RJ
authors: Osborne
authors: S
authors: S
authors: Jones
authors: P F
authors: PF
authors: Wrigley
mesh_terms: D000284:Administration, Oral; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D014508:Urea / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014508:Urea