[Effect of cyanamide on the level of endogenous ethanol in the liver of normal rats and in hypocorticism].
The rat liver endogenous ethanol level was found to increase under inhibition of aldehyde dehydrogenases by cyanamide. Adrenalectomy results in a decrease of the liver endogenous ethanol content and abolishes cyanamide effect on this index. One of the mechanisms of cyanamide toxic effect may be accumulation of different aldehydes including acetaldehyde.
Tarasov
Iu A
IuA
Satanovskaia
V I
VI
Shishkin
S N
SN
Ostrovskiĭ
Iu M
IuM
D000079:Acetaldehyde / Q000378:metabolism; D000309:Adrenal Insufficiency / Q000201:enzymology*; D000315:Adrenalectomy; D000426:Alcohol Dehydrogenase / Q000378:metabolism; D000444:Aldehyde Dehydrogenase / Q000378:metabolism; D000818:Animals; D003484:Cyanamide / Q000494:pharmacology*; D003486:Cyanides / Q000494:pharmacology*; D000431:Ethanol / Q000378:metabolism*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D051381:Rats; D013997:Time Factors
D003486:Cyanides; D000431:Ethanol; D003484:Cyanamide; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase; D000079:Acetaldehyde
Vliianie tsianamida na uroven' éndogennogo étanola v pecheni krys v norme i pri gipokortitsizme.