Fatty acid dependent hydrogen peroxide production in Lactobacillus.
Lactobacillus leichmanii growing in complex medium supplemented with decanoic acid accumulated high concentrations of hydrogen peroxide in the culture. The H2O2-generating system was specifically induced by one of the saturated fatty acids from 4:0 to 16:0 or oleic acid. The induction of this system was associated with the presence of a fatty acyl-CoA-dependent H2O2-generating activity in the cell-free extracts. This activity is shown for the first time in a procaryote organism.
Nuñez de Kairuz
M S
MS
Centro de Referencia para Lactobacillus, CONICET-Fundación Miguel Lillo -FECIC, Tucumán, Argentina.
Olazabal
M E
ME
Oliver
G
G
Pesce de Ruiz Holgado
A A
AA
Massa
E
E
Farías
R N
RN
D003652:Decanoic Acids / Q000494:pharmacology; D006861:Hydrogen Peroxide / Q000378:metabolism*; D007700:Kinetics; D007778:Lactobacillus / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*
D003652:Decanoic Acids; C031071:decanoic acid; D006861:Hydrogen Peroxide