The mucolytic effect of Sputolosin in horses with respiratory disease.
The effect of the mucolytic drug Sputolosin on the clinical signs of respiratory disease among 28 matched pairs of horses was examined. Compared with the untreated group, the treated group showed a significant decrease in the frequency of coughing and a decreased time to resolution of both cough and nasal discharge. The results indicate that the drug is potentially useful in the management of respiratory disease characterised by an abnormal or increased production of mucus.
Matthews
A G
AG
Boehringer Ingelheim Ltd, Bracknell, Berkshire.
Hackett
I J
IJ
Lawton
W A
WA
D000818:Animals; D001596:Benzylamines / Q000627:therapeutic use*; D003371:Cough / Q000188:drug therapy / Q000662:veterinary*; D003511:Cyclohexanols / Q000627:therapeutic use*; D005100:Expectorants / Q000627:therapeutic use*; D005260:Female; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D008297:Male; D012140:Respiratory Tract Diseases / Q000188:drug therapy / Q000662:veterinary*
D001596:Benzylamines; D003511:Cyclohexanols; D005100:Expectorants; C049653:dembrexine