title: [Conservative treatment of breast cancer].
abstract: The paper is concerned with clinical characterization of 81 breast cancer patients after conservative radio- and hormonotherapy. Of the total number of patients 47 suffered from inoperable tumors as a result of local spreading, 30 patients had serious contraindications for the operation, and 4 patients refused surgical intervention. Of the total number of patients 85% were aged over 50, 69%--over 60.41%--over 70, and 4 patients--over 80. The results of radiotherapy after a radical program and administration of antiestrogens (tamoxifen, zitosonium) were evaluated in 71 patients: in 42 tumors were undetectable, in 16 they were reduced by more than 50% of their primary size. An analysis of short-term results during 1-year follow-up showed that of 50 patients complete remission was observed in 24, stabilization of a tumor process was achieved in 8. The results should be regarded as promising with relation to the patients' age, status, tumor spreading, and concomitant diseases.
authors: M M
authors: MM
authors: Nivinskaia
authors: V P
authors: VP
authors: Letiagin
authors: L I
authors: LI
authors: Chebotareva
authors: V M
authors: VM
authors: Ivanov
authors: I D
authors: ID
authors: Klykova
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D009930:Organic Chemicals; D013629:Tamoxifen / Q000627:therapeutic use
chemical_list: D004965:Estrogen Antagonists; D009930:Organic Chemicals; D013629:Tamoxifen; C055999:zitosonium
vernacular_title: Konservatnoe lechenie raka molochnoĭ zhelezy.