title: Alkaline phosphatase positive precursors of adipocytes in the human bone marrow.
abstract: Developing fat cells in the bone marrow of leukaemic patients treated with chemotherapy were found to be endowed with membrane-bound alkaline phosphatase. Since alkaline phosphatase is a cytochemical marker of 'reticular' cells, this observation provides cytochemical evidence that reticular cells may convert to adipocytes when marrow cellularity abruptly decreases.
authors: Department of Human Biopathology, La Sapienza University, Rome, Italy.
authors: P
authors: P
authors: Bianco
authors: M
authors: M
authors: Costantini
authors: L C
authors: LC
authors: Dearden
authors: E
authors: E
authors: Bonucci
mesh_terms: D000208:Acute Disease; D000273:Adipose Tissue / Q000201:enzymology*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D001853:Bone Marrow / Q000473:pathology*; D006801:Humans; D007938:Leukemia / Q000201:enzymology / Q000473:pathology*
chemical_list: D000469:Alkaline Phosphatase