title: Renal tubular damage after renal stone treatment.
abstract: 50 patients were studied with respect to renal tubular damage related to open operative, percutaneous and extracorporeal shock wave treatment of renal stones. Preoperative and postoperative urinary N-acetyl-glucosaminidase (NAG) levels were measured as a marker of renal damage. There was no significant evidence of renal tubular damage in patients who underwent a conventional or percutaneous nephrolithotomy; urinary NAG excretion was significantly increased after ischaemic surgery. After extracorporeal shock wave lithotripsy (ESWL) serum NAG levels increased, probably because a damage of the white blood cells in cutaneous and renal circulation, but a slight increase of urinary NAG excretion could suggest a mild renal tubular damage especially in case of more than 2,000 shocks.
authors: Institute of Urology, Faculty of Medicine, University of Milan, Italy.
authors: A
authors: A
authors: Trinchieri
authors: A
authors: A
authors: Mandressi
authors: G
authors: G
authors: Zanetti
authors: M
authors: M
authors: Ruoppolo
authors: P
authors: P
authors: Tombolini
authors: E
authors: E
authors: Pisani
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine; D003402:Creatine Kinase / Q000032:analysis; D006801:Humans; D007527:Isoenzymes; D007669:Kidney Calculi / Q000473:pathology / Q000628:therapy*; D007684:Kidney Tubules / Q000201:enzymology / Q000473:pathology*; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008096:Lithotripsy
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase; D000118:Acetylglucosaminidase