[Swiss interregional epidemiologic study of the risk of cancer in the contralateral breast].
This epidemiologic investigation in three Swiss regions (Geneva, St. Gall-Appenzell, Vaud) included 5,193 women diagnosed as having a first primary breast cancer. The patients were followed up for ten years (the observation totalled 24,994 women-years). Overall, these results confirmed that the relative risk of a second breast cancer was greatly increased during the first year following the primary diagnosis, but this was largely due to simultaneously discovered contralateral tumours. Beyond the first year of follow-up, the relative risk of a second tumour was lower but still significantly greater than unity. No significant diminution of the excess risk was observed in the first 10 years of follow-up. Relative risk of a second breast cancer was generally higher before age 50, independently of the latency. The relative risk of a second breast cancer differed significantly from one region to another, possibly due to specific techniques of registration.
Obradovic
M
M
Krebsregister St. Gallen-Appenzell, Institut für Pathologie, Kantonsspital.
Enderlin
F
F
Levi
F
F
Gasser
A
A
Raymond
L
L
D000328:Adult; D000367:Age Factors; D001943:Breast Neoplasms / Q000453:epidemiology*; D004282:Documentation; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology*; D011159:Population Surveillance; D012306:Risk; D013557:Switzerland; D013997:Time Factors
Etude épidémiologique inter-régionale suisse du risque de tumeur controlatérale du sein.