[Radioprotective properties of oxolinic acid during long-term exposure to radiation].
The antioxidant activity of oxolinic acid was studied in mongrel mice during the prolonged (6-8 hours) exposure to ionizing radiation. The drug administered before irradiation was shown to increase (by 7 to 33 per cent) the survival rate of mice. The effect was maximum after the subcutaneous injection. The results obtained on the effect of oxolinic acid on DNA synthesis by bone marrow karyocytes are submitted.
Pukhov
V V
VV
Daniiarov
S B
SB
D000818:Animals; D002588:Cesium Radioisotopes; D005720:Gamma Rays; D051379:Mice; D010093:Oxolinic Acid / Q000627:therapeutic use*; D011833:Radiation Injuries, Experimental / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D013997:Time Factors
D002588:Cesium Radioisotopes; D011837:Radiation-Protective Agents; D010093:Oxolinic Acid
Protivoluchevye svoĭstva oksolinovoĭ kisloty pri prolongirovannom radiatsionnom vozdeĭstvii.