title: Slow potential correlates of frontal function, psychosis, and negative symptoms.
abstract: The contingent negative variation (CNV) was used to study cortical activation in frontal and central areas in psychotic and nonpsychotic patients. Psychotic patients showed a higher frontal relative to central CNV amplitude than nonpsychotic patients, a finding that was correlated with performance on a test of frontal function. Negative symptom ratings (physical anhedonia and social closeness) were correlated with relatively low frontal versus central CNV amplitude, but only in psychotic patients.
authors: University of Groningen, The Netherlands.
authors: R J
authors: RJ
authors: van den Bosch
authors: N
authors: N
authors: Rozendaal
authors: J M
authors: JM
authors: Mol
mesh_terms: D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology; D003265:Contingent Negative Variation; D004594:Electrophysiology; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000503:physiopathology; D008875:Middle Aged; D019964:Mood Disorders / Q000503:physiopathology; D011597:Psychomotor Performance / Q000502:physiology; D011618:Psychotic Disorders / Q000503:physiopathology*; D012559:Schizophrenia / Q000503:physiopathology