title: Characterization of two crystal forms of human defensin neutrophil cationic peptide 1, a naturally occurring antimicrobial peptide of leukocytes.
abstract: Two orthorhombic crystal forms (P2(1)2(1)2, a = 30.5 A, b = 44.5 A, c = 40.5 A; I2(1)2(1)2(1) (or I222), a = 30.1 A, b = 66.5 A, c = 35.5 A) of human neutrophil cationic peptide 1 have been characterized. The P2(1)2(1)2 form contains two peptides (Mr = 3425) per asymmetric unit; the I2(1)2(1)2(1) form contains one peptide per asymmetric unit. Both crystal forms diffract to beyond 1.8 A resolution.
authors: Division of Biological and Medical Research, Argonne National Laboratory, Illinois 60439.
authors: R L
authors: RL
authors: Stanfield
authors: E M
authors: EM
authors: Westbrook
authors: M E
authors: ME
authors: Selsted
mesh_terms: D001770:Blood Bactericidal Activity; D001798:Blood Proteins; D003460:Crystallization; D023082:Defensins; D006801:Humans; D010781:Photography
chemical_list: D001798:Blood Proteins; D023082:Defensins