title: LL-F28249 antibiotic complex: a new family of antiparasitic macrocyclic lactones. Isolation, characterization and structures of LL-F28249 alpha, beta, gamma, lambda.
abstract: A new family of antiparasitic macrolides has been isolated from Streptomyces cyaneogriseus sp. noncyanogenus. The compounds, designated LL-F28249 alpha, beta, gamma and lambda, possess potent antiparasitic activity. The isolation, purification and structure determination by spectroscopic methods are presented.
authors: Medical Research Divisio, Lederle Laboratories, American Cyanamid Co., Pearl River, N.Y. 10965.
authors: G T
authors: GT
authors: Carter
authors: J A
authors: JA
authors: Nietsche
authors: M R
authors: MR
authors: Hertz
authors: D R
authors: DR
authors: Williams
authors: M M
authors: MM
authors: Siegel
authors: G O
authors: GO
authors: Morton
authors: J C
authors: JC
authors: James
authors: D B
authors: DB
authors: Borders
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D000969:Antinematodal Agents / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002621:Chemistry; D007783:Lactones / Q000302:isolation & purification*; D018942:Macrolides; D010272:Parasitic Diseases / Q000188:drug therapy; D013302:Streptomyces / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D000969:Antinematodal Agents; D007783:Lactones; D018942:Macrolides; C056044:LL-F 28249lambda; C056041:nemadectin