Antifungal activity of Trillium grandiflorum constituents.
EtOH extracts of the rhizomes and aboveground portion of Trillium grandiflorum showed significant antifungal activity. Bioassay directed fractionation has led to the identification of the active components as the saponin glycosides 1 and 3.
Hufford
C D
CD
Department of Pharmacognosy, School of Pharmacy, University of Mississippi, University 38677.
Liu
S C
SC
Clark
A M
AM
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D002177:Candidiasis / Q000188:drug therapy; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use / Q000633:toxicity; D010946:Plants, Medicinal / Q000032:analysis*
D000935:Antifungal Agents; D010936:Plant Extracts