A simple method for the oral transfer of Moniliformis moniliformis (Acanthocephala) between rats.
A technique is described whereby young adult Moniliformis moniliformis, aged up to 7 days, can be transferred via the oral route from one rat to another. The method is dependent on giving the recipient rats a dose of Cimetidine (0.25 ml/250 g body weight of a solution containing 950 mg/ml) 1 h before transfer. Cimetidine functions as an H2-receptor antagonist and gastric acid secretion in the rat is inhibited temporarily. The technique does not appear to interfere with the reproductive biology of the parasite.
Stoddart
R C
RC
Department of Zoology, University of Glasgow, Scotland.
Crompton
D W
DW
D000049:Acanthocephala / Q000502:physiology*; D000284:Administration, Oral; D000818:Animals; D002927:Cimetidine / Q000008:administration & dosage*; D005744:Gastric Acid / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism; D006373:Helminthiasis / Q000635:transmission*; D008990:Moniliformis / Q000502:physiology*; D010274:Parasitology / Q000379:methods*; D051381:Rats
D002927:Cimetidine