title: Minimum alveolar concentrations (MAC) of halothane, enflurane, and isoflurane in ferrets.
abstract: The minimum alveolar concentrations (MAC) of isoflurane, enflurane, and halothane were determined in adult male ferrets during controlled ventilation at normothermia (37 degrees C). Mean (+/- SD) MAC values for isoflurane (n = 8), enflurane (n = 8), and halothane (n = 8) at 37 degrees C were 1.52 +/- 0.10%, 1.99 +/- 0.18%, and 1.01 +/- 0.10%, respectively. Halothane MAC was reduced by 26% in the presence of 70% N2O. At 29.9 +/- 0.2 degrees C, the mean MAC value of halothane (0.85 +/- 0.11%) was 16% less than MAC at 37 degrees C. The relative potencies of the halogenated anesthetics are of the same order as those reported for large animals and for humans.
authors: Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905.
authors: I
authors: I
authors: Murat
authors: P R
authors: PR
authors: Housmans
mesh_terms: D000818:Animals; D002335:Carnivora; D004737:Enflurane; D005289:Ferrets; D006221:Halothane; D007530:Isoflurane; D008297:Male; D011650:Pulmonary Alveoli
chemical_list: D004737:Enflurane; D007530:Isoflurane; D006221:Halothane