Levels of circulating IgA immune complexes after gluten-rich diet in patients with IgA nephropathy.
Measurement of IgA circulating immune complexes (IgA-CIC) in sera from patients with IgA nephropathy after a gluten-poor diet, an unrestricted diet and a gluten-rich diet is described. High levels of IgA-CIC in sera were detected in patients after these diets. However, the levels of IgA-CIC in sera 2 weeks after the gluten-rich diet were not significantly increased compared with those after the other diets. It is suggested that, for a short duration, the gluten-rich diet might not increase the levels of IgA-CIC in sera from Japanese patients with IgA nephropathy.
Yagame
M
M
Department of Internal Medicine, School of Medicine, Tokai University, Isehara City, Japan.
Tomino
Y
Y
Eguchi
K
K
Miura
M
M
Suga
T
T
Endoh
M
M
Nomoto
Y
Y
Sakai
H
H
D000293:Adolescent; D000328:Adult; D000465:Algorithms; D000936:Antigen-Antibody Complex / Q000032:analysis*; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D005260:Female; D005922:Glomerulonephritis, IGA / Q000276:immunology*; D005983:Glutens / Q000008:administration & dosage*; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008297:Male
D000936:Antigen-Antibody Complex; D004040:Dietary Carbohydrates; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D005983:Glutens