Developmental changes in spinal cord neurite-promoting activity from chick muscle extracts.
Muscle extracts from embryonic chicks aged 10-18 days of embryogenesis produced an increase in 6-day embryo spinal cord neurite initiation. A maximal effect was observed with 18-day extract. Extracts from older chicks produced no effect. These neurite promoting factors are produced at a time in which neuromuscular junctions are forming and becoming stabilized in ovo and may act to control terminal branching, selection, and maintenance of axonal endings.
Thompson
J M
JM
Department of Anatomical Sciences, School of Life Sciences, University of Illinois, Urbana 61801.
Thompson
E G
EG
D000367:Age Factors; D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D003712:Dendrites / Q000187:drug effects / Q000502:physiology*; D009132:Muscles / Q000196:embryology / Q000378:metabolism*; D009414:Nerve Growth Factors / Q000494:pharmacology*; D013116:Spinal Cord / Q000187:drug effects / Q000196:embryology* / Q000502:physiology; D014020:Tissue Extracts / Q000494:pharmacology*
D009414:Nerve Growth Factors; D014020:Tissue Extracts