title: Selective effects of PHA on rat brush border hydrolases along the crypt-villus axis.
abstract: The mechanism of the toxicity of lectin from Phaseolus vulgaris seeds has been investigated on rat enterocytes. Cell isolation procedures showed a selectivity in the loss of brush border hydrolases; this indicated that the microvilli blebbing was not the only mechanism of action of lectins on rat enterocytes.
authors: Laboratoire de Physiologie de la Nutrition, Centre de Génie et Technologie Alimentaires, Montpellier, France.
authors: J M
authors: JM
authors: Rouanet
authors: J
authors: J
authors: Lafont
authors: J L
authors: JL
authors: Zambonino-Infante
authors: P
authors: P
authors: Besançon
mesh_terms: D000818:Animals; D004386:Duodenum / Q000201:enzymology; D006867:Hydrolases / Q000378:metabolism*; D007422:Intestines / Q000201:enzymology*; D008297:Male; D008871:Microvilli / Q000201:enzymology*; D010835:Phytohemagglutinins / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010835:Phytohemagglutinins; D006867:Hydrolases