Osteoporotic correlates of alcoholism in young males.
A group of 22 white males (ages, 28 to 40 years) with histories of chronic alcohol abuse ranging from 1 to 21 years were evaluated for trabecular bone mineral density in the left femoral neck area. A group of age and weight-matched white males with no history of alcoholism served as controls. All participants completed medical history questionnaires regarding fracture history, dietary habits, medications, and physical activity. Singh femoral trabecular indices also were measured for the alcoholic participants. Analysis of bone mineral data as measured by dual photon absorptiometry revealed no statistically significant reduction in the bone mineral densities of the alcoholic group when compared to the controls. No differences were seen in the areas of the femoral neck, Ward's triangle, and greater trochanter. Duration of alcoholism also was not correlated with the degree of osteopenia. Singh index measurements of right and left femoral heads were compared and revealed no significant differences within individual patients. Left femoral Singh index values averaged 5.5 (range, 4 to 6) for the alcoholic group and were not indicative of decreased bone mineral density. It is concluded from this study that chronic alcoholism associated with heavy smoking most likely has a debilitating effect on the trabecular bone density of white males, yet clinical and radiographic evidence is not widely manifested in men under the age of 40 years.
Harding
A
A
Rehabilitation Research and Development, Veterans Administration Medical Center, New Orleans, LA.
Dunlap
J
J
Cook
S
S
Mattalino
A
A
Azar
F
F
O'Brien
M
M
Kester
M
M
D000328:Adult; D000437:Alcoholism / Q000150:complications*; D001851:Bone Diseases, Metabolic / Q000209:etiology*; D001842:Bone and Bones / Q000032:analysis; D006801:Humans; D008297:Male; D008903:Minerals / Q000032:analysis
D008903:Minerals