[Free amino acids and the total middle molecule fraction of the blood serum in patients with continuously progressive paranoid schizophrenia undergoing treatment].
The authors have investigated the levels of free amino acids and of the total fraction of medium molecules in the blood serum of patients with the paranoid form of continuously progressive schizophrenia. It has been demonstrated that these parameters are different in clinically normal individuals versus schizophrenics. The concentrations of free amino acids were the highest in people aged 40 to 50 years (Cys, Ala, Lys, Asp, Thr, Tyr, Try, Val, Leu, Ile) being considerably lower in individuals aged 50 to 60 years (Cys, Ala, Tyr) and over 60 years (Lys, His, Asp, Tyr, Try) which corresponds to the highest activity of the process in patients aged 40 to 50 years and its stabilization in older age.
Mishanich
I I
II
Turianitsa
I M
IM
Pashchenko
A E
AE
Rostoka
L M
LM
Iliushina
S N
SN
D000328:Adult; D000375:Aging / Q000097:blood; D000596:Amino Acids / Q000097:blood*; D002746:Chlorpromazine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008875:Middle Aged; D008970:Molecular Weight; D010455:Peptides / Q000097:blood*; D012563:Schizophrenia, Paranoid / Q000097:blood* / Q000188:drug therapy; D014268:Trifluoperazine / Q000627:therapeutic use
D000596:Amino Acids; D010455:Peptides; D014268:Trifluoperazine; D002746:Chlorpromazine
Svobodnye aminokisloty i obshchaia fraktsiia srednikh molekul syvorotki krovi bol'nykh nepreryvno protekaiushcheĭ paranoidnoĭ shizofrenieĭ, nakhodiashchikhsia na lechenii.