Effects of sex steroids on the development of the locus coeruleus in the rat.
The effects of postnatal (on day 1 (D1) after birth) male orchidectomy and female androgenization on the locus coeruleus (LC) are studied. Normal adult female rats show greater LC volume and cell number than males. Testosterone treatment of females on D1 eliminates these differences. However, D1 male orchidectomy does not affect either the volume or the number of cells.
Guillamón
A
A
Departamento de Psicobiología, Universidad Nacional de Educación a Distancia, Ciudad Universitaria, Madrid, Spain.
de Blas
M R
MR
Segovia
S
S
D000818:Animals; D002452:Cell Count; D005260:Female; D008125:Locus Coeruleus / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D008297:Male; D009919:Orchiectomy; D051381:Rats; D011919:Rats, Inbred Strains; D012727:Sex Characteristics; D013739:Testosterone / Q000494:pharmacology*
D013739:Testosterone