Latent disseminated blastomycosis with choroidal involvement.
A 36-year-old man developed blurred vision and a cough five months after traveling to an area from where a large outbreak of acute blastomycosis had been reported. Examination revealed a left choroidal lesion in the macular region, skin lesions on the right calf, and a left lung apical infiltrate. Histopathologic examination of the skin lesion demonstrated a granulomatous inflammation and broad based, budding yeast characteristic of Blastomyces dermatitidis. Amphotericin B therapy produced a rapid resolution of both choroidal and pulmonary lesions. During a six-month follow-up, there was no evidence of recurrence.
Lewis
H
H
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee.
Aaberg
T M
TM
Fary
D R
DR
Stevens
T S
TS
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001759:Blastomycosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D002829:Choroid / Q000473:pathology*; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D013902:Radiography, Thoracic; D012867:Skin / Q000382:microbiology
D000666:Amphotericin B