[Transcerebral electrophoresis of L-DOPA in the combined treatment of the hyperkinetic form of infantile cerebral palsy].
The authors present a detailed description of transcerebral electrophoresis of L-DOPA conducted in 20 patients aged 9 months to 12 years suffering from a hyperkinetic form of childhood cerebral paralysis. Each patient received 10 sessions. The results of the treatment were assessed by a 5-point score system. Diminution of involuntary movements by 1 point was observed in 1 patient, by 2 points in 10 patients, by 3 points in 7 patients and by 4 points in 1 patient; in one case no positive results were noted. Muscular dystonia and the severity of tonic reflexes decreased in all patients; voluntary movements also improved. Treatment with transcerebral electrophoresis of L-DOPA was well tolerated and was not associated with side-effects.
Kevlishvili
D A
DA
Shubladze
L N
LN
Kvitsaridze
D A
DA
D002547:Cerebral Palsy / Q000150:complications / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D006257:Head; D006801:Humans; D006948:Hyperkinesis / Q000188:drug therapy* / Q000209:etiology; D007223:Infant; D007478:Iontophoresis / Q000379:methods*; D007980:Levodopa / Q000008:administration & dosage* / Q000009:adverse effects; D012996:Solutions
D012996:Solutions; D007980:Levodopa
Transtserebral'nyĭ élektroforez L-DOFA v kompleksnom lechenii giperkineticheskoĭ formy detskogo tserebral'nogo paralicha.