[Comparative efficacy of antibiotic prophylaxis using cefoxitin in one or in three doses in cesarean section].
To compare the effectiveness of three doses and of a single dose of cefoxitin, a second-generation cephalosporin, in preventing infection after nonelective cesarean section, we carried out a prospective study in 255 women who underwent the procedure between March 1983 and February 1985. The rate of postoperative infection was 7% in the group that received three doses and 8% in the one-dose group. The sensitivity and specificity of perioperative cultures were low. The rate of asymptomatic bacteriuria was high, at 20%, but few symptomatic urinary tract infections were found. Routine antibiotic prophylaxis with a single dose is suggested for all nonelective cesarean sections.
Masse
A
A
Département d'Obstétrique-Gynécologie, Hôpital Saint-Luc, Montréal, PQ.
Turgeon
P
P
Gay
N
N
Verschelden
G
G
D000328:Adult; D002440:Cefoxitin / Q000008:administration & dosage*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D011247:Pregnancy; D011292:Premedication; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*
D002440:Cefoxitin
Efficacité comparée de l'antibioprophylaxie par la céfoxitine en une ou trois doses dans la césarienne.