title: Prevention of enteral radiocesium absorption by hexacyanoferrates(II) in piglets.
abstract: The efficacy of different hexacyanoferrates(II) in preventing the enteral absorption of 134Cs was studied in piglets. As compared to the controls, oral application of 134Cs together with KFe[Fe(CN)6], NH4Fe[Fe(CN)6], or Fe4[Fe(CN)6]3 resulted in a strong reduction of the 134 Cs-uptake by more than 97%. The decrease in enteral absorption depends on the dose of administered hexacyanoferrate(II), whereas differences between the compounds under study were small. The biological half-life of 134Cs in non-hexacyanoferrate(II) treated piglets was 21.6 +/- 3.3 days (mean +/- SD).
authors: Institut für Physiologische Chemie, Universitätskrankenhaus Eppendorf, Hamburg, Federal Republic of Germany.
authors: P
authors: P
authors: Nielsen
authors: R
authors: R
authors: Fischer
authors: H C
authors: HC
authors: Heinrich
authors: A A
authors: AA
authors: Pfau
mesh_terms: D000818:Animals; D001822:Body Burden; D002588:Cesium Radioisotopes / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005295:Ferrocyanides / Q000008:administration & dosage / Q000494:pharmacology*; D006207:Half-Life; D007408:Intestinal Absorption / Q000187:drug effects*; D008297:Male; D013552:Swine
chemical_list: D002588:Cesium Radioisotopes; D005295:Ferrocyanides; C020354:hexacyanoferrate II