title: Sequence of two mRNAs encoding active rat tryptophan hydroxylase.
abstract: Two full-length cDNA clones that encode functional rat tryptophan hydroxylase (EC 1.14.16.4), the key enzyme in serotonin synthesis, have been isolated from a rat pineal gland library. These two clones correspond to the 1.8- and 4-kilobase mRNA species, respectively. They contain the same coding sequence corresponding to a 51,010-dalton protein and differ in the length of their 3' untranslated regions.
authors: Laboratoire de Neurobiologie Cellulaire, CNRS, Gif-sur-Yvette; France.
authors: M C
authors: MC
authors: Darmon
authors: B
authors: B
authors: Guibert
authors: V
authors: V
authors: Leviel
authors: M
authors: M
authors: Ehret
authors: M
authors: M
authors: Maitre
authors: J
authors: J
authors: Mallet
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D003062:Codon; D004247:DNA / Q000235:genetics; D004274:DNA, Recombinant; D008969:Molecular Sequence Data; D008970:Molecular Weight; D009693:Nucleic Acid Hybridization; D010870:Pineal Gland / Q000032:analysis; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics*; D011817:Rabbits; D051381:Rats; D014365:Tryptophan Hydroxylase / Q000235:genetics*
chemical_list: D003062:Codon; D004274:DNA, Recombinant; D012333:RNA, Messenger; D004247:DNA; D014365:Tryptophan Hydroxylase