title: Factors affecting mortality in transduodenal sphincteroplasty.
abstract: An analysis of 1,200 consecutive transduodenal sphincterotomies performed between 1967 and 1985 is presented herein. The over-all mortality rate was 3.75 per cent. Since 1980, however, the mortality rate has decreased to 2.1 per cent. The mortality rate was influenced by the age of the patient at the time of the operation (p less than 0.005). Furthermore, the mortality rate increased from decade to decade (less than 30 years, zero per cent; greater than 70 years, 6 per cent). The operative mortality rate was also influenced by general risk factors--hypertony (mortality rate of 5.8 per cent, not significant), diabetes (mortality rate of 6.5 per cent, p congruent to 0.05), renal failure (15.5 per cent, p less than 0.005), jaundice (bilirubin level in survivors, 78.3 micromoles per liter and in those who died, 120.4 micromoles per liter, p less than 0.005) and vital indication (mortality rate of 15 per cent, p less than 0.01). Although the indication for sphincterotomy had a small influence on the mortality (papilla stenosis without bile duct stones, 1.7 per cent; papilla stenosis with common duct stones, 3.6 per cent, and impacted stones in the papilla, 5.0 per cent), these small differences are not significant. A significant influence, however, was due to complicating intraoperative findings, such as bilioenteral fistulas (a mortality rate of 10.8 per cent, p less than 0.0005). The fact that the mortality rate increased in patients with T-tube insertion shows that operative problems and complications influence the mortality rate for sphincterotomy. From these results, we concluded that, in the aforementioned risk groups, a preoperative endoscopic sphincterotomy should be strongly considered, as the risk from the surgical procedure is diminished by the endoscopic relief of the obstruction of the biliary tract.
authors: Kaiser-Franz-Josef-Spital, Wien, Austria.
authors: F J
authors: FJ
authors: Sellner
authors: M
authors: M
authors: Wimberger
authors: R
authors: R
authors: Jelinek
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001663:Bilirubin / Q000097:blood; D001778:Blood Coagulation Disorders / Q000401:mortality; D002779:Cholestasis / Q000601:surgery*; D003920:Diabetes Mellitus / Q000401:mortality; D005260:Female; D006801:Humans; D006973:Hypertension / Q000401:mortality; D007431:Intraoperative Complications / Q000401:mortality; D007565:Jaundice / Q000401:mortality; D007674:Kidney Diseases / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013105:Sphincterotomy, Transduodenal / Q000401:mortality*; D013997:Time Factors
chemical_list: D001663:Bilirubin