[Evaluation of several parameters of coagulation in liver cirrhosis: disseminated intravascular coagulation or pseudo-disseminated intravascular coagulation?].
Reports in the literature on the difficulty of differential diagnosis between Disseminated Intravascular Coagulation (DIC) Pseudo-DIC and Primary Fibrinolysis (PF) in patients with liver disease, stimulated a study of various coagulation parameters (PT, PTT, Platelets, Fibrinogen, FDP) in 28 cirrhotic patients. The study confirmed reports in the literature on the high incidence of circulating FDP among liver disease patients. The vital role these play in maintaining alterations in haemostasis means that cirrhosis cases must be approached with extreme caution, avoiding any therapeutic or instrumental procedure liable to worsen the already disturbed coagulation pattern in such patients.
Petrella
V
V
Divisione di Medicina Generale, U.S.L. n. 54-Borgomanero, Novara.
Parachini
F
F
Rigotti
T
T
Galimberti
M
M
Cusumano
S
S
D000328:Adult; D000368:Aged; D001778:Blood Coagulation Disorders / Q000175:diagnosis; D001780:Blood Coagulation Tests; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D011517:Prothrombin Time
D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen
Valutazione di alcuni parametri di coagulazione in corso di cirrosi epatica: CID o pseudo-CID?