[Morphocytochemical and electron microscopic research on murine hybridoma cells producing and not producing monoclonal antibodies].
Cytochemical and ultrastructural features of mouse hybridomas and also of the parental cells--myeloma P3-X63-Ag8.653 and spleen cells of the Balb/c mice immunized with cell line RPMI-1788 have been studied. Differences in cytomorphological signs and activity of acid phosphatase, acid nonspecific esterase, nonspecific-alpha-naphthyl acetate esterase were shown in hybrid cell lines secreting and not secreting monoclonal antibodies.
Sidorenko
S P
SP
Gluzman
D F
DF
Vetrova
E P
EP
Iurchenko
O V
OV
Berdova
A G
AG
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D002460:Cell Line; D006651:Histocytochemistry; D006825:Hybridomas / Q000201:enzymology / Q000276:immunology / Q000648:ultrastructure*; D007114:Immunization; D051379:Mice; D008807:Mice, Inbred BALB C; D008854:Microscopy, Electron; D009101:Multiple Myeloma / Q000201:enzymology / Q000648:ultrastructure; D013154:Spleen / Q000201:enzymology / Q000648:ultrastructure
D000911:Antibodies, Monoclonal
Morfotsitokhimicheskoe i élektronno-mikroskopicheskoe issledovanie kletok myshinykh gibridom, produtsiruiushchikh i neprodutsiruiushchikh monoklonal'nye antitela.