Chimeric heterosis in mandibular size in mice.
Morphometrical observations were carried out on the mandibles of chimeras made from the embryos of C57BL/6 and BALB/c mice to compare with the two strains and their reciprocal F1 crosses. The results of the principal component analysis indicate that the first principal component (PC1) and the second principal component (PC2) extracted might be acceptable as size and shape factors, respectively. Variations of both PC1 and PC2 were generally larger in the chimeras than in the two component strains and their F1 crosses. The mean PC1 value of the chimeras was larger than that of the two component inbred strains, and it was similar to that of F1 crosses, or slightly larger. The overall size of the mandible represented by PC1 tended to be larger in the chimeras consisting of two component cells that were approximately equivalent than in those that shifted to either cell population. The above trend was observed in both sexes. These results indicate that chimeric heterosis due to the interaction between genetically different cells (C57BL/6 and BALB/c) has some relation to mandible size. The mean PC2 value, which was accepted as shape factor, was intermediate between the two inbred strains. The mandible size (PC1) and shape (PC2) were bilaterally symmetrical, except for the shape in the female chimeras and in (C57BL/6 x BALB/c)F1.
Goto
N
N
Faculty of Agriculture, Kobe University, Japan.
Fukuta
K
K
Imamura
K
K
Ohnishi
A
A
Mikami
H
H
D000818:Animals; D002678:Chimera; D008334:Mandible / Q000033:anatomy & histology*; D051379:Mice; D008807:Mice, Inbred BALB C / Q000033:anatomy & histology* / Q000235:genetics; D008810:Mice, Inbred C57BL / Q000033:anatomy & histology* / Q000235:genetics