Acute ethanol ingestion raises plasma gamma amino-butyric acid levels in healthy men.
The effect of acute ethanol ingestion on plasma gamma aminobutyric acid (GABA) levels was investigated in eight volunteers. Subjects were studied on two days: a control during which light activity and non-alcoholic fluid intake was allowed and a study day during which ethanol was ingested to maintain blood alcohol levels at a mean of 130 mg%. Plasma GABA levels were estimated at 1, 4 and 8 hr. GABA levels were raised at 1 and 4 hr on the study day compared to the control day. GABA levels at 8 hr were not significantly different on the two days. Acute alcohol ingestion raised plasma GABA in healthy male volunteers.
Bannister
P
P
Department of Medicine, St James's University Hospital, Leeds.
Levy
L
L
Bolton
R
R
Losowsky
M S
MS
D000328:Adult; D000431:Ethanol / Q000097:blood / Q000494:pharmacology*; D006801:Humans; D008297:Male; D005680:gamma-Aminobutyric Acid / Q000097:blood*
D000431:Ethanol; D005680:gamma-Aminobutyric Acid