title: Evaluation of iron status in Chadian pregnant women: consequences of maternal iron deficiency on the haematopoietic status of newborns.
abstract: An assessment of iron status was performed on 112 pregnant women at delivery (and on their newborns in 70 cases) and on 114 menstruating women in N'Djamena, Chad. Anaemia (according to the haematocrit value) was observed in 25.0% of pregnant women and in 23.7% of menstruating women. Iron deficiency was defined as the combination of a low serum ferritin level (less than or equal to 12 micrograms/l), a low transferrin saturation (less than 16%) and/or a high erythrocyte protoporphyrin (greater than 3 micrograms/g Hb). A moderate increase in the serum ferritin level (between 13 and 50 micrograms/l) associated with a low transferrin saturation and/or a high erythrocyte protoporphyrin concentration indicated iron-deficiency in an inflammatory context. Iron deficiency was present in 66.9% of pregnant women and in 30.7% of menstruating women. Anaemia was associated with iron deficiency in 78.6% of cases in anaemic pregnant women and in 44.4% of cases in anaemic menstruating women. A correlation between maternal and newborn haematopoiesis was found, and some iron parameters in newborns were related to the iron status of mothers.
authors: Centre de Recherches sur les Anémies Nutritionelles, Institut Scientifique et Technique de l'Alimentation, Paris, France.
authors: A
authors: A
authors: Prual
authors: P
authors: P
authors: Galan
authors: L
authors: L
authors: De Bernis
authors: S
authors: S
authors: Hercberg
mesh_terms: D000328:Adult; D000740:Anemia / Q000453:epidemiology; D000747:Anemia, Hypochromic / Q000453:epidemiology*; D002596:Chad; D004912:Erythrocytes / Q000032:analysis; D005260:Female; D005293:Ferritins / Q000097:blood; D006400:Hematocrit; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007249:Inflammation; D007501:Iron / Q000097:blood*; D008598:Menstruation; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000453:epidemiology*; D011524:Protoporphyrins / Q000097:blood; D014168:Transferrin / Q000032:analysis
chemical_list: D011524:Protoporphyrins; D014168:Transferrin; D005293:Ferritins; D007501:Iron