title: A case of acute pulmonary edema, splenomegaly, and ascites in guinea fowl.
abstract: Acute pulmonary edema, splenomegaly, and ascites were observed in a disease outbreak in adult white and pearl guinea fowl. The clinical history and gross and microscopic lesions resembled those described for marble spleen disease of pheasants and avian adenovirus group II splenomegaly of chickens. A small number of intranuclear inclusion bodies were found in liver, spleen, and lung sections of affected guinea fowl. Attempts to isolate virus and serological tests to detect the presence of viral antigens were unsuccessful. Adult female pearl guinea fowl experimentally exposed to pheasant and turkey isolates of type II avian adenoviruses developed gross and microscopic lesions similar to those seen in the field outbreak. The pheasant isolate was the more virulent. Intranuclear inclusion bodies were observed in liver, spleen, and lung sections of pearl guinea fowl inoculated with either of the virus isolates, and direct immunofluorescent examination revealed viral antigen in the spleen and lung.
authors: Department of Veterinary Science, College of Agriculture, Pennsylvania State University, University Park 16802.
authors: B S
authors: BS
authors: Cowen
authors: H
authors: H
authors: Rothenbacher
authors: L D
authors: LD
authors: Schwartz
authors: M O
authors: MO
authors: Braune
authors: R L
authors: RL
authors: Owen
mesh_terms: D000818:Animals; D001201:Ascites / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D001715:Bird Diseases / Q000473:pathology*; D001717:Birds; D005260:Female; D011654:Pulmonary Edema / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D013163:Splenomegaly / Q000150:complications / Q000473:pathology / Q000662:veterinary*