title: A comparison of cell size changes in central and pericentral representations within the primate lateral geniculate nucleus following early monocular deprivation.
abstract: Mean cell areas have been measured in the most posterior part of the lateral geniculate nucleus containing the representation of central retina in 8 normal monkeys (Macaca mulatta) and in 5 monkeys following monocular closure from birth. Comparisons with cell size changes at a more anterior level, where pericentral retina is represented, show that size changes of parvocellular cells at the posterior level are significantly less, being only between half and two-thirds of those more anteriorly. The undeprived cells undergo less initial hypertrophy than cells at a more anterior level and subsequently the deprived cells show less shrinkage. There is no comparable difference for magnocellular cells.
authors: Department of Human Anatomy, University of Oxford, U.K.
authors: J J
authors: JJ
authors: Sloper
authors: M P
authors: MP
authors: Headon
authors: T P
authors: TP
authors: Powell
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D007839:Functional Laterality / Q000502:physiology*; D005829:Geniculate Bodies / Q000254:growth & development / Q000473:pathology / Q000502:physiology*; D006984:Hypertrophy; D008253:Macaca mulatta; D009473:Neuronal Plasticity; D014785:Vision, Ocular / Q000502:physiology*