Cardiovascular and respiratory effects of oral premedication with trimeprazine and droperidol in children.
The systolic blood pressure, pulse rate and respiratory rate were assessed in 112 children before and after receiving premedication consisting of trimeprazine (3 mg/kg) and droperidol (0.2 mg/kg) by mouth. A mild (10%) drop in blood pressure was shown, but no statistical difference was found in the other parameters measured. The premedication is highly efficacious, 70% of patients being asleep in the preanaesthetic room; 27% were calm and only 3% were distressed or crying.
Butt
A D
AD
Department of Anaesthesia, University of Cape Town.
Mets
B
B
D000284:Administration, Oral; D001794:Blood Pressure / Q000187:drug effects*; D002648:Child; D002675:Child, Preschool; D004329:Droperidol / Q000008:administration & dosage / Q000494:pharmacology*; D004359:Drug Therapy, Combination; D006801:Humans; D007223:Infant; D011292:Premedication; D011446:Prospective Studies; D011674:Pulse / Q000187:drug effects*; D012119:Respiration / Q000187:drug effects*; D014291:Trimeprazine / Q000008:administration & dosage / Q000494:pharmacology*
D014291:Trimeprazine; D004329:Droperidol