title: Necrotizing keratitis caused by Capnocytophaga ochracea.
abstract: We studied three cases of Capnocytophaga keratitis that demonstrated stromal necrosis and a ring infiltrate. In all cases, the keratitis occurred in a previously diseased or traumatized cornea. One patient was treated with chronic antiamoebic therapy for presumed Acanthamoeba keratitis. Two cases resulted in corneal perforation. Laboratory isolation was difficult because of slow, fastidious growth. Capnocytophaga is not uniformly sensitive to commonly used topical antibiotics such as the cephalosporins and aminoglycosides, but may respond to treatment with topical clindamycin.
authors: Department of Ophthalmology, William Beaumont Hospital, Detroit, Michigan.
authors: D G
authors: DG
authors: Heidemann
authors: S C
authors: SC
authors: Pflugfelder
authors: J
authors: J
authors: Kronish
authors: E C
authors: EC
authors: Alfonso
authors: S P
authors: SP
authors: Dunn
authors: S
authors: S
authors: Ullman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections; D002206:Capnocytophaga; D003316:Corneal Diseases / Q000601:surgery; D005131:Eye Injuries / Q000150:complications; D005260:Female; D006801:Humans; D007634:Keratitis / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D008297:Male; D009336:Necrosis; D011183:Postoperative Complications; D012997:Solvents / Q000009:adverse effects; D014949:Wounds, Nonpenetrating / Q000150:complications
chemical_list: D012997:Solvents