Tobacco smoking and exposure to dust and gas pollution in the place of work and lung cancer risk.
A case-control study has been applied to analyze lung cancer risk, isolating four histopathological groups: differentiated forms of cancer (most often carcinoma planoepitheliale and adenocarcinoma), undifferentiated carcinomas (mainly carcinoma microcellulare and solidum), cancers histologically undeterminated (carcinoma) and cancers not verified histologically, but confirmes radiologically and clinically. 210 patients have been compared with the group of 420 men not suffering from any form of cancer. The results of the undertaken attempt to evaluate lung cancers in relation to certain etiological factors (conditions in the microenvironment of the place of work and tobacco smoking) showed that the influence of tobacco smoking (independently of the kind of tobacco and the form of smoking) on lung cancer incidence was more and more firmly established, and the frequency of incidence increased with the length of the period of smoking. Tobacco smokers and those simultaneously exposed to various dusts and dusts with gases in their microenvironment of the place of work were characterized by higher lung cancer risk (in fact independently on the histological form of the neoplasms), as compared to nonsmokers and those never exposed to air pollution.
Zemła
B
B
Institute of Oncology, Gliwice, Poland.
Zielonka
I
I
Kołosza
Z
Z
D000393:Air Pollutants / Q000009:adverse effects*; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D008175:Lung Neoplasms / Q000145:classification / Q000209:etiology* / Q000473:pathology; D009784:Occupational Diseases / Q000209:etiology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*
D000393:Air Pollutants; D004391:Dust