[Efficacy of a low-residue diet in the prevention of immuno-nutritional changes caused by the preparation of the colon for surgery].
Twenty-four patients about to undergo colorectal resection for cancer were randomly divided into two groups of 12: A and B. All had an uninterrupted colonic preparation for colonoscopy and surgery involving dietary restrictions for 4-8 days (450 calories; 25 g. proteins daily). In the group B an additional intake of 1200 Kcal. and 32 g. protein daily was given by a low-residue diet. Body weight, lymphocytes, albumin, prealbumin, C3, C4 and Complement activity (CH100) were evaluated on admission and after bowel preparation. In group A statistically significant decrease were found in all the parameters. In group B significant reduction occurred only in C4. The data confirm a relationship between immuno-nutritional state and preparation for colonic surgery, and suggest that a preoperative nutritional support may avoid or limit bio-humoral changes, indicative of an immuno-nutritional impairment.
Montanari
M
M
Università degli Studi di Parma, Istituto di Clinica Chirurgica Generale II.
Violi
V
V
De Bernardinis
M
M
Artioli
M
M
Pellegrini
M
M
Roncoroni
L
L
D000368:Aged; D003106:Colon / Q000601:surgery*; D003113:Colonoscopy; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003165:Complement System Proteins / Q000032:analysis; D004032:Diet; D004044:Dietary Proteins / Q000008:administration & dosage; D004733:Enema; D005260:Female; D006801:Humans; D007109:Immunity; D007958:Leukocyte Count; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D011228:Prealbumin / Q000032:analysis; D011300:Preoperative Care; D012709:Serum Albumin / Q000032:analysis
D003176:Complement C3; D003181:Complement C4; D004044:Dietary Proteins; D011228:Prealbumin; D012709:Serum Albumin; D003165:Complement System Proteins
Efficacia di una dieta a basso residuo nella prevenzione delle alterazioni immunonutrizionali indotte dalla preparazione del colon.