Methylphenidate in treating poststroke depression.
The authors retrospectively studied the charts of 25 patients with poststroke depression who were treated with methylphenidate. The 13 patients (52%) who recovered completely from their depression did not differ significantly from the 12 nonresponders on demographic characteristics, location of cerebrovascular accident, and other variables. Mood usually improved within 48 hours; only 3 (12%) patients had side effects. Rapid response to treatment and lack of significant side effects indicate that methylphenidate may be a valuable treatment for poststroke depression.
Lingam
V R
VR
Walter P. Reuther Psychiatric Hospital, Westland, Mich. 48185.
Lazarus
L W
LW
Groves
L
L
Oh
S H
SH
D000368:Aged; D002561:Cerebrovascular Disorders / Q000150:complications*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000209:etiology / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use*; D012189:Retrospective Studies
D008774:Methylphenidate