Phenobarbital-induced buccolingual dyskinesia in oral apraxia.
A young woman with oral apraxia and a well-defined brain lesion on CT scan developed buccolingual dyskinesia lasting 40 days after low phenobarbital (PB) doses. Disruption of the corticostriatal glutamatergic pathway from areas 6 and 4 may have been important both in causing oral apraxia and in lowering the threshold for PB-induced buccolingual dyskinesia.
Sechi
G P
GP
Department of Neurology, University of Sassari, Italy.
Piras
M R
MR
Rosati
G
G
Zuddas
M
M
Ortu
R
R
Tanca
S
S
Agnetti
V
V
D000328:Adult; D001072:Apraxias / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D001921:Brain / Q000000981:diagnostic imaging; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D009059:Mouth Diseases / Q000209:etiology; D010634:Phenobarbital / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D010634:Phenobarbital