[Pharmacological studies of "reiousan" which contains bezoar and ginseng].
Pharmacological properties of "Reiousan", a crude drug preparation consisting of bezoar and ginseng, were studied. The hypotensive effect on spontaneously hypertensive rat, inhibition of platelet aggregation, acetic acid-induced writhing, stress ulcer, CCl4 and d-galactosamine-induced hepatic injury, and facilitation of recovery from neuroparalysis and muscular fatigue, protective effect on anoxic brain damages, antipyretic effect, and facilitation of learning in aged mice were observed after administration of "Reiousan". It was suggested that bezoar and ginseng act synergistically in causing the hypotensive effect, acetic acid-induced writhing and drug-induced hepatic injury, and protection from anoxic brain damages and muscular fatigue.
Morishita
S
S
Research Laboratories, Kyushin Pharmaceutical Co., Ltd., Tokyo, Japan.
Saito
T
T
Shoji
M
M
Hirai
Y
Y
Tanaka
A
A
D000818:Animals; D000959:Antihypertensive Agents; D004338:Drug Combinations; D007858:Learning / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008297:Male; D008419:Materia Medica; D051379:Mice; D008815:Mice, Inbred Strains; D005894:Panax; D010946:Plants, Medicinal; D010974:Platelet Aggregation / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D011918:Rats, Inbred SHR; D011919:Rats, Inbred Strains
D000959:Antihypertensive Agents; D004338:Drug Combinations; D008419:Materia Medica