Ultrastructural study on meningeal regeneration and meningo-glial relationships after cerebral stab wound in the adult rat.
Meningeal regeneration and meninges-glial relationships during the reparation of an experimental brain stab wound, are studied with the electron microscope. At 14 days after the wound, a continuous newly formed basal lamina separates both nervous and meningeal tissues. Later, the astroglial processes of regenerated glia limitans showed very infolded surfaces and numerous filaments inside of them. Across the cavity left by the wound, filament-rich astroglial processes, forming bundles or glial cords of variable diameter, were seen. Each glial cord was surrounded by a basal lamina covered on the outside by a discontinuous sheet of meningocytic processes. Although regenerated meningocytes displayed interlacing processes forming a loose reticular network, large cellular meningocyte masses were also found.
Carbonell
A L
AL
Department of Histology and General Embryology, Faculty of Medicine, University Complutense, Madrid, Spain.
Boya
J
J
D000818:Animals; D001930:Brain Injuries / Q000473:pathology*; D008578:Meninges / Q000502:physiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009416:Nerve Regeneration; D009457:Neuroglia / Q000502:physiology* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014951:Wounds, Stab