[Changes in the composition of double-stranded sequences of poly(A)-containing RNA in cell cytoplasm during hormonal induction].
Double-stranded segments (c-ds) have been studied in the poly(A)+ cytoplasmic rat liver RNA. Duplexes about 40 base pairs long have been shown to be of intermolecular character and originate from the interaction between ss-RNA and complementary regions of the poly(A)-containing RNA molecules. Shorter ds-sequences are, mainly, of intramolecular nature. Double-stranded sequences of different length differ also in their oligonucleotide composition, according to fingerprint analysis data. Under the action of cortisone, only several kinds of double-stranded sequences have been demonstrated to increase in the population of cytoplasmic poly(A)+RNA. The function of ds-regions in the hormonal regulation of gene expression is suggested.
Konstantinova
I M
IM
Kozlov
Iu V
IuV
Kulichkova
V A
VA
Petukhova
O A
OA
Kurmanova
A G
AG
D000818:Animals; D003348:Cortisone / Q000031:analogs & derivatives* / Q000494:pharmacology; D003593:Cytoplasm / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D008099:Liver / Q000032:analysis* / Q000187:drug effects; D009692:Nucleic Acid Heteroduplexes / Q000302:isolation & purification; D009710:Nucleotide Mapping; D011061:Poly A / Q000032:analysis*; D012330:RNA, Double-Stranded / Q000302:isolation & purification*; D051381:Rats; D011919:Rats, Inbred Strains
D009692:Nucleic Acid Heteroduplexes; D012330:RNA, Double-Stranded; D011061:Poly A; D003348:Cortisone
Izmenenie sostava dvuspiral'nykh posledovatel'nosteĭ poli(A)-soderzhashchikh RNK tsitoplazmy kletok pri gormonal'noĭ induktsii.