title: [Ovarian changes in the progeny of females subjected to prolonged cooling].
abstract: The ovaries of immature offspring of the females, subjected to cooling (+5 degrees-+7 degrees C) for 80 days (including pregnancy period) have been investigated. As a control the ovaries of immature offspring of the females, living in the vivarium have been studied. By means of the light optic, electron microscopic, fluorescent-histochemical and morphometric methods, analysis of the generative structures and activity of the sympathetic innervation of the ovaries of performed. Ultramicroscopic organization of ovocytes with early signs of destruction is examined. In the animals of the test group total number of follicles and indices of sympathetic mediation of the ovaries decrease, while more than two-fold increase of ovocytes with signs of destruction is noted, predominantly in the primordial follicles. Thus, a prolonged adaptation of the female to cooling results in certain changes of the ovarian reproductive function in the offspring.
authors: L M
authors: LM
authors: Mel'nikova
mesh_terms: D000818:Animals; D003080:Cold Temperature / Q000009:adverse effects*; D005260:Female; D009865:Oocytes / Q000648:ultrastructure; D010053:Ovary / Q000294:innervation / Q000502:physiology / Q000648:ultrastructure*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D013997:Time Factors
vernacular_title: Izmeneniia iaichnikov potomstva samok, podvergnutykh dlitel'nomu okhlazhdeniiu.