Tamoxifen in advanced prostate cancer: an ECOG pilot study.
A group of 19 patients with advanced (Stage D) prostate cancer were treated with one of three dose levels of the anti-estrogen tamoxifen, 10 mg (3 patients), 20 mg (8 patients), or 30 mg (8 patients) daily. Five patients had received no prior systemic therapy. The treatment was tolerated well, but no objective responses occurred.
Horton
J
J
Albany Medical College, Division of Oncology, NY 12208.
Rosenbaum
C
C
Cummings
F J
FJ
D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography; D006801:Humans; D008297:Male; D010865:Pilot Projects; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000503:physiopathology; D013629:Tamoxifen / Q000627:therapeutic use*
D013629:Tamoxifen