title: Stable isotope metabolic studies of zinc nutrition in slum-dwelling lactating women in the Amazon valley.
abstract: 1. Zinc metabolism has been studied in a group of undernourished, slum-dwelling, lactating women in Manaus, Brazil, by means of modified metabolic balance techniques and the stable isotope 67Zn. 2. The subjects were found to be consuming a diet which provided an average of 34% of the recommended dietary allowance for lactating women, but six of the seven appeared to achieve Zn balance. In five of the subjects use of 67Zn in a stable isotope dilution manner demonstrated that they were absorbing a high proportion of the dietary Zn (proportional absorption ranged from 0.59 to 0.84), suggesting an adaptation to the chronically low intake. 3. Two subjects had marginally low plasma Zn concentrations, although hair, urine and milk Zn contents were all within accepted normal values. 4. Preliminary findings on the rate of plasma Zn turnover and the size of the exchangeable body Zn pool obtained using 67Zn suggest that these subjects may have a reduction in both.
authors: Department of Medicine, University of Liverpool.
authors: M J
authors: MJ
authors: Jackson
authors: R
authors: R
authors: Giugliano
authors: L G
authors: LG
authors: Giugliano
authors: E F
authors: EF
authors: Oliveira
authors: R
authors: R
authors: Shrimpton
authors: I G
authors: IG
authors: Swainbank
mesh_terms: D001938:Brazil; D004032:Diet; D004064:Digestive System / Q000378:metabolism; D005260:Female; D006801:Humans; D007774:Lactation / Q000378:metabolism*; D009747:Nutritional Physiological Phenomena; D011204:Poverty Areas; D011247:Pregnancy; D015032:Zinc / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism* / Q000493:pharmacokinetics; D015033:Zinc Isotopes
chemical_list: D015033:Zinc Isotopes; D015032:Zinc