Pneumonia following experimental bronchial obstruction in sheep.
Five of 7 sheep in which the bronchi supplying the right apical lobe of the lung were obstructed with a cottonwool plug developed pneumonia. Large numbers of bacteria were isolated from 4 of the 5 pneumonic lungs. Only minor pulmonary lesions, which are common in sheep on pasture, were observed in 5 sham operation and 5 control sheep. These results support a role for airway obstruction in compromising the antimicrobial defences of the lungs in naturally occurring bacterial pneumonias of sheep.
Pfeffer
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Wallaceville Animal Research Centre, MAFTech, Ministry of Agriculture and Fisheries, Upper Hutt, New Zealand.
D000818:Animals; D001980:Bronchi / Q000382:microbiology / Q000473:pathology; D003352:Corynebacterium / Q000302:isolation & purification; D008173:Lung Diseases, Obstructive / Q000150:complications; D008297:Male; D010325:Pasteurella / Q000302:isolation & purification; D011014:Pneumonia / Q000453:epidemiology / Q000209:etiology*; D012756:Sheep; D013291:Streptococcus / Q000302:isolation & purification