title: Disseminated intravascular coagulation accompanying thoracic and abdominal aortic aneurysm; report of three cases.
abstract: We reported three patients who developed disseminated intravascular coagulation (DIC) accompanying thoracic and abdominal aortic aneurysm. The first case, a 26-year-old man with dissecting aortic aneurysm developed DIC with clinical bleeding after operating on glaucoma. The administration of fibrinogen concentrates and antifibrinolytic agent made his DIC improve. The second case, a 70-year-old man with abdominal aortic aneurysm developed DIC showing large ecchymosis after angiography. His DIC disappeared after operation on aneurysm. The third case, a 73-year-old woman with thoracic and abdominal aneurysm developed laboratory-DIC without severe hemorrhagic diathesis. During antifibrinolytic therapy, platelet count, fibrinogen and fibrinogen degradation product (FDP) level improved. Since the treatment of the coagulopathy might be varied in the situation of the cause and clinical course, it is noted that anti-fibrinolytic therapy was effective in our two cases.
authors: Third Department of Internal Medicine, Akita University School of Medicine, Japan.
authors: S
authors: S
authors: Mamiya
authors: Y
authors: Y
authors: Endo
authors: A B
authors: AB
authors: Miura
authors: T
authors: T
authors: Kanazawa
authors: A
authors: A
authors: Kuwayama
authors: S
authors: S
authors: Nishimura
mesh_terms: D000328:Adult; D000368:Aged; D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D001012:Aorta, Abdominal; D001013:Aorta, Thoracic; D001014:Aortic Aneurysm / Q000150:complications*; D004211:Disseminated Intravascular Coagulation / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D006801:Humans; D008297:Male
chemical_list: D000933:Antifibrinolytic Agents; D005338:Fibrin Fibrinogen Degradation Products