Identification of three isoform patterns of human serum amyloid A protein.
Three patterns of human apo-SAA (serum amyloid A protein) isoforms have been identified by electrofocusing. In pattern 1, six major apo-SAA isoforms of pI 6.0, 6.4, 7.0, 7.4, 7.5 and 8.0 were found. In pattern 2, the apo-SAA isoforms of pI 7.4 and 8.0 were not detected, whereas in pattern 3 the pI-7.0 and -7.5 isoforms were lacking. Six patients displayed apo-SAA isoform pattern 1, 11 displayed pattern 2 and one displayed pattern 3.
Strachan
A F
AF
Department of Internal Medicine, University of Stellenbosch Medical School, Tygerberg, South Africa.
de Beer
F C
FC
van der Westhuyzen
D R
DR
Coetzee
G A
GA
D000328:Adult; D000686:Amyloidosis / Q000097:blood; D001059:Apoproteins / Q000097:blood*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged; D000685:Serum Amyloid A Protein / Q000032:analysis*
D001059:Apoproteins; D000685:Serum Amyloid A Protein