Calcification of the central nervous system in a new hereditary neurological syndrome.
A case of a new hereditary neurological condition with extensive calcifications of the central nervous system is described. The calcium deposits were especially localized to the leptomeninges, the first layer of the cerebral and cerebellar cortex, and along the ventricular wall. The neuropathological findings were in accordance with the clinic. The case was familial and the pedigree suggested an X-linked recessive inheritance.
Reske-Nielsen
E
E
Department of Neuropathology, Aarhus Kommunehospital, Denmark.
Jensen
P K
PK
Hein-Sørensen
O
O
Abelskov
K
K
D000328:Adult; D001284:Atrophy; D001921:Brain / Q000473:pathology*; D002114:Calcinosis / Q000235:genetics* / Q000473:pathology; D003704:Dementia / Q000235:genetics / Q000473:pathology*; D034381:Hearing Loss / Q000235:genetics*; D006312:Hearing Loss, Bilateral / Q000235:genetics*; D006319:Hearing Loss, Sensorineural / Q000235:genetics*; D006801:Humans; D008297:Male; D008578:Meninges / Q000473:pathology; D009896:Optic Atrophy / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D013116:Spinal Cord / Q000473:pathology*; D013577:Syndrome; D014960:X Chromosome