Continuous flow fast atom bombardment liquid chromatography/mass spectrometry: studies involving conventional bore liquid chromatography with simultaneous ultraviolet detection.
A conventional bore liquid chromatograph has been interfaced to quadrupole and magnetic sector mass spectrometers configured for fast atom bombardment ionization via a continuous flow FAB probe. It is shown that post-column addition of FAB matrix and in-line ultraviolet detection facilities do not significantly compromise chromatographic integrity and that high quality mass spectra are obtainable from such FAB LC/MS studies.
Games
D E
DE
Department of Chemistry, University College, Cardiff, UK.
Pleasance
S
S
Ramsey
E D
ED
McDowall
M A
MA
D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods; D004743:Enkephalin, Leucine / Q000032:analysis*; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
D004743:Enkephalin, Leucine