Serotonin innervation of neuropeptide Y-containing neurons in the rat arcuate nucleus.
Structural non-synaptic appositions between serotonin (5-HT) nerve endings and neuropeptide Y (NPY)-containing neurons were demonstrated in the rat arcuate nucleus by means of a combined radioautographic and immunocytochemical detection of [3H]5-HT uptake sites and NPY-immunoreactivity. Such cellular relationships are proposed to constitute a morphological substrate for putative 5-HT/NPY interactions in neuroendocrine hypothalamus.
Guy
J
J
MRC Group in Molecular Endocrinology, Laval University Medical Center, Quebec, Canada.
Pelletier
G
G
Bosler
O
O
D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000032:analysis* / Q000648:ultrastructure; D001345:Autoradiography; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000032:analysis / Q000648:ultrastructure; D009478:Neuropeptide Y / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000032:analysis*
D009478:Neuropeptide Y; D012701:Serotonin