title: The level of natural antioxidant glutathione and histidine-containing dipeptides in skeletal muscles of developing chick embryos.
abstract: 1. The levels of glutathione and histidine-containing dipeptides in skeletal muscles change in different ways during ontogenesis. 2. The glutathione content in skeletal muscles increases between the 9th and 18th days of embryongenesis--from 0.5 to 2.0 mumol/g of tissue wet wt and then drops to zero in 3-week-old chickens. 3. The level of histidine-containing dipeptides increases throughout the observation period beginning with their appearance on the 14th day in leg muscles and on the 15th day in breast muscles of chicken embryos up to the 21st postnatal day. 4. There is a negative correlation between the antioxidative systems of glutathione and histidine-containing dipeptides in muscle tissue, i.e. dipeptide-rich tissues contain little or no glutathione and vice versa.
authors: Department of Biochemistry, School of Biology, Moscow State University, U.S.S.R.
authors: A A
authors: AA
authors: Boldyrev
authors: A M
authors: AM
authors: Dupin
authors: M
authors: M
authors: Siambela
authors: S L
authors: SL
authors: Stvolinsky
mesh_terms: D000818:Animals; D000861:Anserine / Q000378:metabolism; D002336:Carnosine / Q000378:metabolism; D002642:Chick Embryo / Q000254:growth & development* / Q000378:metabolism; D004151:Dipeptides / Q000032:analysis*; D005978:Glutathione / Q000378:metabolism*; D006639:Histidine / Q000032:analysis*; D009132:Muscles / Q000032:analysis*; D012016:Reference Values
chemical_list: D004151:Dipeptides; D006639:Histidine; D002336:Carnosine; D005978:Glutathione; D000861:Anserine