Effect of butoconazole nitrate cream and wax insert on the barrier property of contraceptive devices.
A new method was developed to assess the quality of the barrier property of several types of commonly used contraceptive devices (diaphragm, cervical cap, and condom). Our data showed that butoconazole nitrate cream and wax inserts did not affect the barrier property of the contraceptive devices when the products were placed in contact with the devices for up to 72 hours at 37 degrees C.
Wong
A B
AB
Syntex Research, Palo Alto, CA 94303.
D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology*; D003273:Contraceptive Devices; D003274:Contraceptive Devices, Female; D003275:Contraceptive Devices, Male; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D014622:Vaginal Creams, Foams, and Jellies / Q000494:pharmacology*; D014885:Waxes / Q000494:pharmacology*
D000935:Antifungal Agents; D007093:Imidazoles; D014622:Vaginal Creams, Foams, and Jellies; D014885:Waxes; C017125:butoconazole