Inhibitory action of garlic oil on the initiation of benzo[a]pyrene-induced skin carcinogenesis in mice.
When garlic oil was topically applied during the initiation phase of benzo[a]pyrene (B(a)P)-induced skin carcinogenesis in random bred adult female Swiss albino mice of two different substrains, there was a decline in the number of tumor-bearing mice as well as in the mean number of tumors per effective mouse.
Sadhana
A S
AS
Department of Anatomy, All India Institute of Medical Sciences, New Delhi.
Rao
A R
AR
Kucheria
K
K
Bijani
V
V
D000498:Allyl Compounds; D000818:Animals; D001564:Benzo(a)pyrene; D005260:Female; D051379:Mice; D012878:Skin Neoplasms / Q000139:chemically induced / Q000517:prevention & control*; D013440:Sulfides / Q000494:pharmacology*
D000498:Allyl Compounds; D013440:Sulfides; D001564:Benzo(a)pyrene; C038491:allyl sulfide