Lack of interferon production by dipyridamole.
Dipyridamole, previously reported to be an interferon (IFN) inducer in mice, was evaluated in 43 normal volunteers or cancer patients. At doses ranging from 150 mg orally to 887 mg intravenously, no serum antiviral activity suggesting IFN induction was observed.
Havlin
K A
KA
University of Wisconsin Clinical Cancer Center, Madison 53792.
Inglot
A D
AD
Willson
J K
JK
Borden
E C
EC
Grossberg
S
S
Szulc
B
B
Gladysz
A
A
Groehlich
B
B
D004176:Dipyridamole / Q000494:pharmacology*; D006801:Humans; D007369:Interferon Inducers
D007369:Interferon Inducers; D004176:Dipyridamole