The effect of vitamin A supplementation on tear fluid retinol levels of marginally nourished preschool children.
Vitamin A has been determined in tear fluid and blood plasma of marginally nourished Thai children before and after supplementation with a single, oral dose of 110 mg retinyl palmitate. After two months a significant rise of tear fluid retinol levels of the supplemented group was observed as compared to the non-supplemented group, while after four months no difference could be found. Determination of vitamin A levels in tear fluid may be useful in clinical eye research, with special regard to xerophthalmia.
van Agtmaal
E J
EJ
The Netherlands Ophthalmic Research Institute, Biochemical Laboratory, Amsterdam.
Bloem
M W
MW
Speek
A J
AJ
Saowakontha
S
S
Schreurs
H P
HP
van Haeringen
N J
NJ
D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009748:Nutrition Disorders / Q000188:drug therapy* / Q000453:epidemiology / Q000378:metabolism; D013666:Tears / Q000378:metabolism*; D013785:Thailand; D014801:Vitamin A / Q000378:metabolism / Q000627:therapeutic use*
D014801:Vitamin A