The incidence of allergy to propolis in 605 consecutive patients patch tested in Prague.
605 consecutive patients were patch tested with the standard CDRG test series and with a 10% alcoholic solution of propolis. Positive allergic reactions to propolis were observed in 25 patients (4.2%); thirteen of them exhibited a simultaneous positive patch test to balsam of Peru. In view of the relatively high incidence of allergic reactions and the appearance of pseudo-cross-sensitivity to another common allergen, balsam of Peru, propolis should not be used in topical medicaments or as a component of cosmetic preparations.
Machácková
J
J
1st Dermatological Clinic, Medical School of Charles University, Prague, Czechoslovakia.
D000279:Administration, Cutaneous; D001453:Balsams / Q000276:immunology / Q000627:therapeutic use; D003429:Cross Reactions; D003604:Czechoslovakia; D003877:Dermatitis, Contact / Q000209:etiology*; D006801:Humans; D010328:Patch Tests; D011429:Propolis / Q000276:immunology* / Q000627:therapeutic use; D012116:Resins, Plant / Q000276:immunology*
D001453:Balsams; D012116:Resins, Plant; C025080:Peruvian balsam; D011429:Propolis