[Cytophotometric analysis of the nuclear DNA content in oral squamous cell carcinoma--relation between nuclear DNA content and clinico-pathologic findings].
Cytophotometric analysis has been performed on Feulgen-stained nuclei in smears taken from 48 biopsy specimens of squamous cell carcinoma of the oral cavity. The results were correlated with the clinico-pathologic findings of the tumor. DNA histograms were graded into three patterns: P-I (2C-2C), P-II (2C-6C) and P-III (2C-beyond 6C). DNA patterns of the carcinoma of the clinical stage I, II tended to be P-I, II and those of stage III, IV were mostly P-II, III. DNA patterns of carcinomas which were well differentiated and poorly pleomorphic with a few number of mitoses, were mostly P-I, whereas those which were poorly differentiated and remarkably pleomorphic with a many number of mitoses were mostly P-III.
Iwai
M
M
Dept. of Oral and Maxillo-facial Surgery, Faculty of Med. Toyama Medical and Pharmaceutical Univ.
Kohama
G
G
Odajima
T
T
Furuta
I
I
D002294:Carcinoma, Squamous Cell / Q000032:analysis / Q000473:pathology*; D002455:Cell Division; D002467:Cell Nucleus / Q000032:analysis; D004273:DNA, Neoplasm / Q000032:analysis*; D006801:Humans; D008938:Mitosis; D009062:Mouth Neoplasms / Q000032:analysis / Q000473:pathology*
D004273:DNA, Neoplasm