Successful resuscitation using external cardiac pacing in beta adrenergic antagonist-induced bradyasystolic arrest.
We present a case of attempted suicide by propranolol overdose presenting as convulsions followed by bradyasystolic cardiopulmonary arrest successfully managed by external transcutaneous pacing. Inotropic support and the resulting clinical improvement permitted discontinuation of cardiac pacing after 75 minutes. Pharmacologic management included glucagon late in the patient's management when the persistent hypotension was established to be due to beta adrenergic blockade. A serum propranolol level of 2,331 ng/mL verified the overdose. This is the first report of successful transcutaneous pacing for beta adrenergic antagonist poisoning.
Kenyon
C J
CJ
Department of Emergency Medicine, Saint Francis Hospital, Evanston, Illinois.
Aldinger
G E
GE
Joshipura
P
P
Zaid
G J
GJ
D000328:Adult; D002304:Cardiac Pacing, Artificial; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced / Q000628:therapy*; D006801:Humans; D011433:Propranolol / Q000506:poisoning*; D012151:Resuscitation / Q000379:methods*; D013406:Suicide, Attempted
D011433:Propranolol