The effects of lead in laboratory animals and environmentally-exposed children.
Consistent association has been found in 4 independent studies between disruption of visual-motor integration and reaction performance and markers of lead exposure (blood, teeth) in children, but not for intelligence deficit; blood-lead levels were typically below 30 micrograms/dl in these children. In order to demonstrate the persistent nature of Pb-induced neurobehavioral deficit experimentally rats were studied after cessation of dietary Pb-exposure in a variety of behavioral tasks. Persistent retention-deficit was found for visual discrimination-learning and for radical arm-maze performance.
Winneke
G
G
Department of Psychophysiology, University of Düsseldorf, F.R.G.
Collet
W
W
Lilienthal
H
H
D000293:Adolescent; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002648:Child; D004781:Environmental Exposure; D006801:Humans; D007360:Intelligence / Q000187:drug effects*; D007854:Lead / Q000633:toxicity*; D011597:Psychomotor Performance / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains
D007854:Lead