title: Hexamminecobaltic chloride provides a simple method for marking neurones for electron microscopy.
abstract: Intracellular injection of hexamminecobaltic chloride into a neurone causes characteristic changes to the structure of its mitochondria. This provides a simple technique to label neuronal profiles for examination of their ultrastructure. Synaptic structures are not affected by hexamminecobaltic ions.
authors: Department of Biology, University of Newcastle upon Tyne, U.K.
authors: P M
authors: PM
authors: Littlewood
authors: P J
authors: PJ
authors: Simmons
mesh_terms: D000818:Animals; D002712:Chlorides; D003035:Cobalt; D006110:Grasshoppers; D007202:Indicators and Reagents; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D009474:Neurons / Q000648:ultrastructure*; D011073:Polyamines; D013569:Synapses / Q000648:ultrastructure
chemical_list: D002712:Chlorides; D007202:Indicators and Reagents; D011073:Polyamines; C007936:hexaminecobalt (III) trichloride; D003035:Cobalt