Early DNA damage induced in cells exposed to N10-propargyl 5,8-dideazafolic acid (CB 3717) or methotrexate.
Lorico
A
A
Division of Experimental Oncology 1, Centro di Riferimento Oncologico, Aviano, PN, Italy.
Toffoli
G
G
Boiocchi
M
M
Erba
E
E
Broggini
M
M
Rappa
G
G
D'Incalci
M
M
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004247:DNA / Q000187:drug effects*; D004249:DNA Damage; D005492:Folic Acid / Q000031:analogs & derivatives* / Q000633:toxicity; D008727:Methotrexate / Q000494:pharmacology*; D051379:Mice; D011799:Quinazolines / Q000633:toxicity*; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors
D011799:Quinazolines; C031662:CB 3717; D004247:DNA; D005492:Folic Acid; D013940:Thymidylate Synthase; D008727:Methotrexate