[Activation of natural antitumor resistance in cancer patients during a delayed hypersensitivity reaction].
Factors influencing the effectiveness of BCG vaccine employed as part of complex therapy were studied in cases of lung and gastrointestinal cancer. The drug showed clinical effect and stimulated the effector function of monocytes, natural and antibody-dependent killers in tuberculin-positive patients only. The degree of stimulation was in correlation with that of delayed hypersensitivity reaction. A relationship between stimulation, increase in the level of effector-cells and intensification of cytolytic activity was established.
Gordienko
S M
SM
Novichev
A P
AP
Avdiunicheva
O E
OE
Churilova
L A
LA
D000328:Adult; D000920:Antibody-Dependent Cell Cytotoxicity; D001500:BCG Vaccine / Q000627:therapeutic use; D005770:Gastrointestinal Neoplasms / Q000276:immunology* / Q000628:therapy; D006801:Humans; D006968:Hypersensitivity, Delayed; D007694:Killer Cells, Natural / Q000276:immunology*; D007963:Leukocytes, Mononuclear / Q000276:immunology; D008175:Lung Neoplasms / Q000276:immunology* / Q000628:therapy; D014374:Tuberculin Test
D001500:BCG Vaccine
Aktivatsiia estestvennoĭ protivoopukholevoĭ rezistentnosti u onkologicheskikh bol'nykh pri reaktsii giperchuvstvitel'nosti zamedlennogo tipa.