Polarization of nerve regeneration (electrotaxis).
Regeneration of both median nerves was studied in the rat in three different experimental models of centrocentral anastomosis through an interposed segment of pre-degenerated tibial nerve after denervation by spinal root transection. Different patterns of regeneration were observed in the anastomoses. These patterns suggest a bio-electrical polarity related to neuronal function. The present experimental model appears to offer a new opportunity to study neuronal regeneration under the influence of defined bioelectrical conditions.
Shibib
K
K
Neurosurgical Department, Klinikum Steglitz, Free University of Berlin, Federal Republic of Germany.
Brock
M
M
Buljat
G
G
Gosztonyi
G
G
Schoknecht
G
G
D000714:Anastomosis, Surgical; D000818:Animals; D001369:Axons / Q000502:physiology; D004594:Electrophysiology; D008475:Median Nerve / Q000166:cytology / Q000502:physiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D009416:Nerve Regeneration; D013979:Tibial Nerve / Q000637:transplantation