The metacarpal index in homozygous sickle-cell disease.
The metacarpal index (MCI) was measured in 240 patients with homozygous sickle-cell (SS) disease and in 1082 normal persons constituting a comparison group. The MCI was greater in females than in males, but there appeared to be no significant difference between genotypes. Arachnodactyly may occur in some patients with SS disease, but there is no evidence of a genotype-related increase in metacarpal index.
Walker
T M
TM
Medical Research Council Laboratories, Jamaica, University of the West Indies, Kingston.
Dunn
D T
DT
Serjeant
G R
GR
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008663:Metacarpus / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D012737:Sex Factors