title: Behavioral and morphological effects of oculomotor nucleus lesion on abducens internuclear neurons in the cat.
abstract: The activity of identified control and injured abducens internuclear neurons was recorded during spontaneous eye movements in the alert cat. From 2 days following the electrocoagulation of the contralateral oculomotor nucleus, abducens internuclear neurons showed a quick fatigability during eye fixations not observed in controls. Discharge rate during saccades started after the beginning of the eye movement and showed a fast exponential-like decay. These abnormal responses were not further recorded from 20 days following the lesion. Morphological studies indicated that 90% of the abducens internuclear neuron population disappeared 2 months following the lesion and showed no sign of recovery one year later.
authors: Departamento de Fisiología Animal, Facultad de Biología, Universidad de Sevilla, Spain.
authors: J M
authors: JM
authors: Delgado-Garciá
authors: M
authors: M
authors: Escudero
authors: B
authors: B
authors: Torres
authors: F
authors: F
authors: Portillo
authors: R
authors: R
authors: Pásaro
mesh_terms: D000010:Abducens Nerve / Q000502:physiology*; D000818:Animals; D001369:Axons / Q000502:physiology; D002415:Cats; D004558:Electric Stimulation; D005133:Eye Movements; D007839:Functional Laterality; D008564:Membrane Potentials; D009474:Neurons / Q000502:physiology*; D009802:Oculomotor Nerve / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology