Topical diphenhydramine toxicity in a five year old with varicella.
The toxic effects of oral diphenhydramine are well documented and include central nervous system and anticholinergic symptomatology. We present a case of diphenhydramine intoxication from combined oral/percutaneous medication. Overzealous application of a commercially available topical diphenhydramine preparation resulted in hallucinations and other side effects in a five-year-old child with varicella.
Woodward
G A
GA
Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia.
Baldassano
R N
RN
D000279:Administration, Cutaneous; D002644:Chickenpox / Q000188:drug therapy*; D002675:Child, Preschool; D004155:Diphenhydramine / Q000008:administration & dosage / Q000506:poisoning*; D006212:Hallucinations / Q000139:chemically induced*; D006801:Humans; D008297:Male; D004366:Nonprescription Drugs / Q000506:poisoning
D004366:Nonprescription Drugs; D004155:Diphenhydramine