Relationship between alveolar-arterial PO2 and PCO2 differences and the contact time in the lung capillary.
From the numerical solutions of simultaneous O2 and CO2 diffusions in the RBC, we calculated the P(A-a)CO2 by varying the tc at various PvO2 and PvCO2 levels, whereas the PAO2 and PACO2 were kept constant at 90 and 40 Torr, respectively. From the results we could clarify the relationship between the P(A-a)CO2 and the tc and its dependency on PvO2 and PvCO2. Furthermore, the influence of the tc on the C(a-v)O2, C(v-a)CO2 and R was clarified quantitatively.
Mochizuki
M
M
Geriatric Respiratory Research Center, Nishimaruyama Hospital, Sapporo/Chuo-Ku, Japan.
Kagawa
T
T
D000818:Animals; D002196:Capillaries / Q000502:physiology; D002244:Carbon / Q000097:blood / Q000378:metabolism*; D003198:Computer Simulation; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D010100:Oxygen / Q000097:blood / Q000378:metabolism*; D010313:Partial Pressure; D011650:Pulmonary Alveoli / Q000502:physiology*; D011652:Pulmonary Circulation
D002244:Carbon; D010100:Oxygen