Embryotoxic effects of thalidomide derivatives in the non-human primate Callithrix jacchus. II. Elucidation of the susceptible period and of the variability of embryonic stages.
Data are presented on the normal intra- and inter-litter variability of the embryonic stages in the common marmoset (Callithrix jacchus) on day 56 of pregnancy. The embryology of the marmoset is described with respect to the susceptible period for the teratogenic action of thalidomide.
Neubert
D
D
Institut für Toxikologie und Embryopharmakologie, Freie Universität Berlin, Germany.
Heger
W
W
Merker
H J
HJ
Sames
K
K
Meister
R
R
D000818:Animals; D002144:Callithrix; D004622:Embryo, Mammalian / Q000187:drug effects*; D005314:Embryonic and Fetal Development / Q000187:drug effects; D005260:Female; D005865:Gestational Age; D008297:Male; D010060:Ovulation; D011247:Pregnancy; D011280:Pregnanolone / Q000031:analogs & derivatives / Q000652:urine; D013045:Species Specificity; D013792:Thalidomide / Q000633:toxicity*
C013051:17-hydroxypregnanolone; D013792:Thalidomide; D011280:Pregnanolone