[Effect of carnosine on intraocular pressure].
It has been demonstrated in experiments on non-anesthetized rabbits that conjunctival injection of carnosine (beta-alanyl 1-histidine) caused a decrease in normal intraocular pressure and reduced prostaglandin-induced ocular hypertension. The rapid onset of the pressure response and the absence of papillary dilation in rabbits treated with carnosine were observed. It is concluded that L-carnosine can be used as a potent drug for the prevention of reactive hypertension syndrome.
Ermakova
V N
VN
Babizhaev
M A
MA
Bunin
A Ia
AIa
D000818:Animals; D002336:Carnosine / Q000494:pharmacology*; D004151:Dipeptides / Q000494:pharmacology*; D007429:Intraocular Pressure / Q000187:drug effects*; D009798:Ocular Hypertension / Q000139:chemically induced / Q000517:prevention & control; D011448:Prostaglandin Antagonists / Q000627:therapeutic use; D011817:Rabbits
D004151:Dipeptides; D011448:Prostaglandin Antagonists; D002336:Carnosine
Vliianie karnozina na vnutriglaznoe davlenie]