Deep heat in the treatment of inflammatory joint disease.
There is now a growing body of clinical evidence suggesting a therapeutic approach to cancer and prostatic hypertrophy by using hyperthermia. It is proposed that such a hyperthermic modality can produce thermal synovectomy in inflammatory arthritis. Heating the joint cavity up to 42 deg C can inhibit the enzymatic effect of collagenase, oxygenase, and other enzymes playing a role in the inflammatory process. If this hypothesis is correct, therapeutic intervention using hyperthermia may offer hope for the treatment of isolated inflammatory joint diseases.
Weinberger
A
A
Dept. of Medicine D, Beilinson Medical Center, Petah-Tikva, Israel.
Fadilah
R
R
Lev
A
A
Levi
A
A
Pinkhas
J
J
D001168:Arthritis / Q000503:physiopathology / Q000628:therapy*; D001831:Body Temperature; D002455:Cell Division; D006358:Hot Temperature; D006801:Humans; D006820:Hyaluronic Acid / Q000096:biosynthesis; D006979:Hyperthermia, Induced; D008954:Models, Biological; D010146:Pain / Q000503:physiopathology; D010525:Peripheral Nerves / Q000503:physiopathology; D013583:Synovial Membrane / Q000098:blood supply / Q000378:metabolism
D006820:Hyaluronic Acid