Micronuclei in X-irradiated human lymphocytes.
The dose-effect relationship of the frequency of micronuclei in cytokinesis-blocked human lymphocytes after in vitro irradiation of whole blood in the range from 0.2 to 4 Gy was studied. The linear-quadratic response obtained offers a useful technique for dose assessments in cases of radiation injuries above approx. 0.1 Gy whole body dose. The distribution in size of micronuclei in cytochalasin B treated cells ranges to larger diameters than in mononuclear lymphoblasts.
Kormos
C
C
'Frédéric Joliot-Curie' National Research Institue for Radiobiology and Radiohygiene, Budapest, Hungary.
Köteles
G J
GJ
D000328:Adult; D002467:Cell Nucleus / Q000648:ultrastructure; D002869:Chromosome Aberrations; D003571:Cytochalasin B / Q000494:pharmacology; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000528:radiation effects*; D014965:X-Rays
D003571:Cytochalasin B