title: The presence of tyramine and related monoamines in the nerve cord and some other tissues of the lobster, Homarus americanus.
abstract: This report shows the existence of endogenous p-tyramine in the nerve cord and some organs of the lobster. Their concentrations are lower than those of dopamine or 5-hydroxytryptamine. The nerve cord levels of m-tyramine, beta-phenylethylamine and tryptamine are much lower than those of the phenolic or catecholic amines. The finding that the administration of an aromatic-L-amino acid decarboxylase inhibitor leads to a decrease of p-tyramine gives further evidence that this amine is synthesized from p-tyrosine, which is also found in high concentrations in the lobster nerve cord. The widespread distribution of p-tyramine in the nervous system and peripheral tissues of the lobster suggests that this amine may have additional roles rather than functioning only as a precursor of p-octopamine.
authors: Neuropsychiatric Research Unit, University of Saskatchewan, Saskatoon, Canada.
authors: A V
authors: AV
authors: Juorio
authors: B D
authors: BD
authors: Sloley
mesh_terms: D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D005260:Female; D008297:Male; D008750:Methyldopa / Q000031:analogs & derivatives / Q000494:pharmacology; D008121:Nephropidae / Q000378:metabolism*; D009420:Nervous System / Q000378:metabolism*; D009994:Osmolar Concentration; D014018:Tissue Distribution; D014439:Tyramine / Q000378:metabolism*
chemical_list: D001679:Biogenic Amines; D008750:Methyldopa; C019494:alpha-monofluoromethyldopa; D014439:Tyramine