Melatonin plasma response to MAO inhibitor: influence on human pineal activity?
Strong negative correlation has been observed between nighttime (physiological) elevation of plasma melatonin and plasma melatonin increase induced by a single dose of MAO inhibitor, tranylcypromine. The possible use of acute plasma melatonin response to MAO inhibitor as a functional test for the evaluation of human pineal activity is discussed.
Oxenkrug
G F
GF
Department of Psychiatry, Wayne State University School of Medicine, Detroit, Michigan.
Balon
R
R
Jain
A K
AK
McIntyre
I M
IM
D002940:Circadian Rhythm; D006801:Humans; D008550:Melatonin / Q000097:blood*; D010870:Pineal Gland / Q000502:physiology*; D014191:Tranylcypromine / Q000494:pharmacology*
D014191:Tranylcypromine; D008550:Melatonin