The effect of nalbuphine on the common bile duct pressure.
The effect of Nalbuphine on the common bile duct pressure of ten women who had cholecystectomy and common duct exploration for cholelithiasis and choledocholithiasis was studied. In this pilot study, intravenously inject Nalbuphine (20 mg) significantly raised the common duct pressure (P less than 0.01). However, none of the patients experienced pain as a result of the elevation in the biliary pressure; there was no deleterious cardiopulmonary effect.
Butsch
J L
JL
State University of N.Y. Medical School, Buffalo.
Okoli
J A
JA
D000328:Adult; D000368:Aged; D003135:Common Bile Duct / Q000187:drug effects* / Q000502:physiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009019:Morphinans / Q000494:pharmacology*; D009266:Nalbuphine / Q000494:pharmacology*; D011312:Pressure
D009019:Morphinans; D009266:Nalbuphine