Treatment of complications of cyclophosphamide cystitis.
Since 1976, 23 patients with cyclophosphamide-induced cystitis were treated. These patients presented with a variety of urinary problems, including incontinence, hematuria and vesicoureteral reflux. Vesicoureteral reflux was found in 9 patients, hydronephrosis in 4 and a contracted fibrotic bladder in 3. Of the 23 patients 18 had undergone a combination of radiation and cyclophosphamide therapy. Based on this experience a general outline is developed for evaluation and treatment of patients with cyclophosphamide-induced cystitis and its potentially severe complications.
Jerkins
G R
GR
Department of Pediatric Urology, University of Tennessee, Memphis.
Noe
H N
HN
Hill
D
D
D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D003556:Cystitis / Q000139:chemically induced* / Q000628:therapy; D005260:Female; D006417:Hematuria / Q000139:chemically induced; D006801:Humans; D006869:Hydronephrosis / Q000139:chemically induced; D008297:Male; D014549:Urinary Incontinence / Q000139:chemically induced; D014718:Vesico-Ureteral Reflux / Q000139:chemically induced
D003520:Cyclophosphamide