[Applicability of micronucleus analysis for testing the aneuploid cell level in mouse bone marrow subjected to the action of different mutagenic factors].
The results of parallel studies in murine bone marrow of aneuploid cells' level and of micronuclei cells under the action of different mutagenic factors (X-irradiation, ethanol, measles virus and colchicine) are presented. The correlation analysis demonstrated the absence of correlation for the indices studied, in most cases. Possible reasons for this phenomenon are discussed.
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D000782:Aneuploidy; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects / Q000648:ultrastructure*; D001856:Bone Marrow Examination / Q000379:methods; D002467:Cell Nucleus / Q000187:drug effects / Q000528:radiation effects / Q000648:ultrastructure*; D003078:Colchicine / Q000494:pharmacology; D000431:Ethanol / Q000494:pharmacology; D008459:Measles virus / Q000472:pathogenicity; D051379:Mice; D009154:Mutation
D000431:Ethanol; D003078:Colchicine
Primenimost' mikroiadernogo analiza dlia testirovaniia urovnia aneuploidnykh kletok v kostnom mozge mysheĭ, podvergnutykh vozdeĭstviiu razlichnymi mutagennymi faktorami.