Pancytopenia following low-dose oral methotrexate therapy for psoriasis.
Low-dose oral methotrexate therapy was associated with the onset of anemia, leukopenia, and thrombocytopenia in two patients with psoriasis. Both patients survived, but required prolonged hospitalization. No precipitating factor other than methotrexate could be identified.
Shupack
J L
JL
Department of Dermatology, New York University Medical Center, NY 10016.
Webster
G F
GF
D000284:Administration, Oral; D000368:Aged; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D010198:Pancytopenia / Q000139:chemically induced*; D011565:Psoriasis / Q000188:drug therapy*
D008727:Methotrexate