[Brain metabolism of sarcoma 45-bearing rats undergoing radiation and the effect of hyperthermia on the tumor].
Activity of hexokinase and acetylcholinesterase and pyridoxal co-enzyme content of brain subcellular fractions were studied in rats, bearing sarcoma 45, after local exposure of the tumor to 20 Gy X-radiation and microwave hyperthermia. The carbohydrate metabolism was sharply inhibited while the pyridoxal coenzyme content and acetylcholinesterase activity increased.
Khripchenko
I P
IP
Pikulev
A T
AT
Kukulianskaia
M F
MF
Val'shteĭn
M M
MM
Burtseva
O E
OE
D000110:Acetylcholinesterase / Q000378:metabolism / Q000528:radiation effects; D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000528:radiation effects; D006593:Hexokinase / Q000378:metabolism / Q000528:radiation effects; D006979:Hyperthermia, Induced; D008297:Male; D009368:Neoplasm Transplantation; D011732:Pyridoxal Phosphate / Q000378:metabolism / Q000528:radiation effects; D011733:Pyridoxamine / Q000031:analogs & derivatives / Q000378:metabolism / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains; D012513:Sarcoma, Experimental / Q000201:enzymology* / Q000532:radiotherapy; D013997:Time Factors
D011732:Pyridoxal Phosphate; D011733:Pyridoxamine; D006593:Hexokinase; D000110:Acetylcholinesterase; C010627:pyridoxamine phosphate
Nekotorye storony metabolizma mozga krys-opukholenositeleĭ sarkomy 45 pri radiatsionnom i gipertermicheskom vozdeĭstviiakh na opukhol'.