title: Nonfluorescent dicentric Y in males with hypospadias.
abstract: We report three boys with severe hypospadias and bilaterally palpable testes with abnormalities of the Y chromosome detected by Q-banding. Severe hypospadias with palpable testes is an unusual presentation for Y chromosome abnormalities. Based on our experience, we recommend that boys with this phenotype undergo complete cytogenetic evaluation, because Y chromosome abnormalities prompt additional management concerns.
authors.affiliation: Department of Medicine, University of Washington School of Medicine, Seattle.
authors.forename: M
authors.initials: M
authors.lastname: Drummond-Borg
authors.forename: R A
authors.initials: RA
authors.lastname: Pagon
authors.forename: C M
authors.initials: CM
authors.lastname: Bradley
authors.forename: J
authors.initials: J
authors.lastname: Nordlund
authors.forename: D
authors.initials: D
authors.lastname: Salk
mesh_terms: D006801:Humans; D007021:Hypospadias / Q000235:genetics*; D007231:Infant, Newborn; D008297:Male; D010641:Phenotype; D012729:Sex Chromosome Aberrations; D014998:Y Chromosome