title: Treatment of senile entropion with botulinum toxin.
abstract: Botulinum toxin was used to treat senile entropion in 12 patients by injection into the preseptal orbicularis muscle of the lower lids. It produced relief of symptoms in 10 patients but this was transient, lasting for an average of 14.8 weeks before orbicularis function returned. The technique is simple and easy to perform, and may be useful in selected patients, but surgery offers a more permanent result.
authors.affiliation: Medical Eye Unit, St Thomas's Hospital, London.
authors.forename: J R
authors.initials: JR
authors.lastname: Clarke
authors.forename: D J
authors.initials: DJ
authors.lastname: Spalton
mesh_terms: D000109:Acetylcholine / Q000037:antagonists & inhibitors; D000368:Aged; D000369:Aged, 80 and over; D001905:Botulinum Toxins / Q000627:therapeutic use*; D004774:Entropion / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000627:therapeutic use; D009801:Oculomotor Muscles / Q000187:drug effects; D013997:Time Factors
chemical_list: D009466:Neuromuscular Blocking Agents; D001905:Botulinum Toxins; D000109:Acetylcholine