Excretion of 3-methylhistidine by pregnant women: evidence for a biphasic system of protein metabolism in human pregnancy.
A positive nitrogen balance is established in early pregnancy and persists unchanged until parturition. The excretion of 3-methylhistidine is markedly increased in late pregnancy, indicating that protein retained in the maternal muscles in early pregnancy is later catabolized to provide a major source of amino acids for fetal protein synthesis.
Naismith
D J
DJ
Department of Food and Nutritional Sciences, King's College London, University of London, UK.
Emery
P W
PW
D000328:Adult; D005260:Female; D006639:Histidine / Q000031:analogs & derivatives*; D006801:Humans; D008762:Methylhistidines / Q000652:urine*; D009124:Muscle Proteins / Q000378:metabolism*; D009215:Myometrium / Q000378:metabolism*; D011247:Pregnancy / Q000378:metabolism*; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third
D008762:Methylhistidines; D009124:Muscle Proteins; D006639:Histidine; C028118:3-methylhistidine