title: Primary immunodeficiency diseases in children treated in the Children's Memorial Hospital, Poland.
abstract: One hundred and three cases of primary immunodeficiency diseases were diagnosed among children suffering mainly from chronic and severe infections in the period 1980-1987. Predominantly antibody defects were recognized in 48 patients (46.6%), combined immunodeficiencies in 36 patients (35%), phagocytic disorders in 12 patients (11.6%), complement defects in 6 patients (5.8%), and cell-mediated disease (Di George syndrome) in 1 patient. Allergic complications were observed in 25 patients (24.2%) and malignancy-in 3 patients (2.9%). More detailed immunological studies were performed in children with X-linked agammaglobulinemia in the course of intravenous immunoglobulin therapy and in children with ataxia telangiectasia.
authors.affiliation: Department of Immunology, Children's Memorial Hospital, Warsaw, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Bernatowska
authors.forename: K
authors.initials: K
authors.lastname: Madalinski
authors.forename: J
authors.initials: J
authors.lastname: Michalkiewicz
authors.forename: H
authors.initials: H
authors.lastname: Gregorek
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000453:epidemiology* / Q000628:therapy; D008297:Male; D009369:Neoplasms / Q000145:classification; D011044:Poland