title: Stratified application of the automatic implantable cardioverter defibrillator.
abstract: Since June 1983 we have developed a stratified regimen for staged implantation of the automatic implantable cardioverter defibrillator system. The protocol for management in patients who have fully recovered from sudden cardiac death is initiated with the use of standard electrophysiologic evaluation. Treatment in order of application has consisted of drugs followed by implantation of the device for patients with drug-refractory arrhythmias in whom direct cardiac surgical intervention for anatomic substrates for sudden death are absent. In surgical candidates, combinations of coronary revascularization and ablative therapy have been used to mitigrate the potential for lethal arrhythmia. Sensing and defibrillator lead systems have been placed at corrective operations to be followed later by implantation of the cardioverter defibrillator generator for either inducible or spontaneous tachyarrhythmia. This staged application has been effective in markedly reducing actual sudden cardiac death while at the same time saving on unnecessary device implantation. Morbidity of lead implantation alone remains a concern, particularly for infective complications. Additional follow-up is required to assess the validity of this approach.
authors.affiliation: Department of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee 53226.
authors.forename: G N
authors.initials: GN
authors.lastname: Olinger
authors.forename: P D
authors.initials: PD
authors.lastname: Chapman
authors.forename: P J
authors.initials: PJ
authors.lastname: Troup
authors.forename: G H
authors.initials: GH
authors.lastname: Almassi
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D002315:Cardiopulmonary Bypass; D003131:Combined Modality Therapy; D003645:Death, Sudden; D004554:Electric Countershock / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization; D013610:Tachycardia / Q000628:therapy*; D014693:Ventricular Fibrillation / Q000628:therapy*
chemical_list: D000889:Anti-Arrhythmia Agents