Absence of a vagina and right sided adnexa uteri in the Waardenburg syndrome: a possible clue to the embryological defect.
An 18 year old single Jewish woman with the Waardenburg syndrome and absence of a vagina and right sided adnexa uteri is reported. Other congenital malformations associated with the Waardenburg syndrome are mentioned and it is postulated that they may be the result of an altered invasion of neurones or altered neurones in certain organ systems early in embryogenesis.
Goodman
R M
RM
Department of Medical Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Oelsner
G
G
Berkenstadt
M
M
Admon
D
D
D000015:Abnormalities, Multiple / Q000196:embryology*; D000290:Adnexa Uteri / Q000002:abnormalities*; D000293:Adolescent; D005260:Female; D006801:Humans; D014621:Vagina / Q000002:abnormalities*; D014849:Waardenburg Syndrome / Q000196:embryology*