[Natural killer cells in patients with chronic alcoholism].
The study of the activity of natural killer cells in patients with chronic alcoholism, stage II, has revealed its essential decrease in comparison with that in healthy subjects, which is particularly pronounced with effector/target cell ratio equal to 100:1 and 50:1 respectively. Besides, two subgroups can be differentiated among the total population of alcoholic patients: subgroup 1 with the activity of killer cells remaining practically intact and subgroup 2 with profound defects in the functioning of these cells. The presence of essential defects in natural killer cells of patients with the severe form of alcoholism is suggested.
Chermeneva
L M
LM
Dovgiĭ
A V
AV
Cheknev
S B
SB
D000328:Adult; D000437:Alcoholism / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D000431:Ethanol / Q000009:adverse effects; D006801:Humans; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000276:immunology*; D013375:Substance Withdrawal Syndrome / Q000276:immunology
D000431:Ethanol
Estestvennye kletki-killery u bol'nykh khronicheskim alkogolizmom.