title: Spontaneous regression of a small non-cleaved cell malignant lymphoma (non-Burkitt's lymphoblastic lymphoma). Morphologic, immunohistological, and immunoglobulin gene analysis.
abstract: Complete spontaneous regression of high-grade malignant non-Hodgkin's lymphoma is extremely unusual. In this report the authors describe a complete spontaneous remission after surgical excisional biopsy of a small noncleaved cell malignant lymphoma (non-Burkitt's lymphoblastic lymphoma) of the tonsil in a 12-year-old boy. The diagnosis was confirmed by immunohistologic and immunoglobulin gene analysis. Similar studies were performed on the cervical lymph node excised 2 weeks later when spontaneous remission had occurred. The patient has remained in good health for over 3 years.
authors.affiliation: Department of Pathology, University of Groningen, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Poppema
authors.forename: L
authors.initials: L
authors.lastname: Postma
authors.forename: M
authors.initials: M
authors.lastname: Brinker
authors.forename: B
authors.initials: B
authors.lastname: de Jong
mesh_terms: D000293:Adolescent; D000951:Antigens, Neoplasm / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000235:genetics; D007150:Immunohistochemistry; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology / Q000473:pathology*; D008297:Male; D009365:Neoplasm Regression, Spontaneous; D009693:Nucleic Acid Hybridization; D014067:Tonsillar Neoplasms / Q000276:immunology / Q000473:pathology*
chemical_list: D000951:Antigens, Neoplasm; D007136:Immunoglobulins