High-frequency attenuation measurements using an acoustic microscope.
An acoustic microscope was used to measure excess attenuation of aqueous solutions of sugars and proteins at 1.0 GHz. Interference pattern spacing and peak amplitude reduction of V(z) curves, obtained with these solutions as the acoustic microscope coupling liquid, were related to the solution wavespeed and attenuation, respectively. Consistent with published results for lower frequencies, solutions with molecular weight greater than 10,000 had a higher specific absorption than those with a molecular weight less than 1000 and within these two molecular weight ranges specific absorption was independent of concentration.
Gracewski
S M
SM
Department of Mechanical Engineering, University of Rochester, New York 14627.
Waag
R C
RC
Schenk
E A
EA
D000042:Absorption; D002241:Carbohydrates / Q000493:pharmacokinetics*; D006454:Hemoglobins / Q000493:pharmacokinetics*; D006801:Humans; D066298:In Vitro Techniques; D008853:Microscopy / Q000295:instrumentation; D008970:Molecular Weight; D011506:Proteins / Q000493:pharmacokinetics*; D014465:Ultrasonics
D002241:Carbohydrates; D006454:Hemoglobins; D011506:Proteins