title: [Pleurisy and sarcoidosis].
abstract: Two cases of sarcoidosis associated with pleurisy are presented. The pleural effusion had the same characteristics in both cases. Histology showed non-caseating epithelioid and giant cell granulomas in the parietal pleura. The first case was consistent with sarcoid pleurisy, but in the second case culture of a pleural biopsy specimen fragment demonstrated tuberculous pleurisy. Pleurisy may complicate sarcoidosis in about 2.5% of patients, notably in extensive pulmonary sarcoidosis with extrathoracic lesions. The clinical presentation and the appearance of the pleural fluid are varied. In most cases, a predominantly lymphocytic sero-fibrinous exudate is present. Thorough bacteriological studies, best performed on pleural tissue cultures, must follow the discovery of non-caseating tuberculoid granulomas which are also found in tuberculous pleurisy. Among the various pathogenetic theories considered, the immune reaction theory deserves special mention.
authors.affiliation: Hôpital d'Instruction des Armées Percy, Service de Pneumologie, Clamart.
authors.forename: F
authors.initials: F
authors.lastname: Natali
authors.forename: J D
authors.initials: JD
authors.lastname: Heyraud
authors.forename: F
authors.initials: F
authors.lastname: Vaylet
authors.forename: A
authors.initials: A
authors.lastname: Ben Nasser
authors.forename: C
authors.initials: C
authors.lastname: Maurel
authors.forename: P
authors.initials: P
authors.lastname: Allard
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000473:pathology; D010998:Pleurisy / Q000209:etiology* / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology
vernacular_title: Pleurésie et sarcoïdose.