[Animal experiment studies of morphologic changes in the trachea and lung in high frequency ventilation].
Prolonged high frequency ventilation (24 hrs) in dogs leads to morphological changes in the trachea as well as in the bronchi. Erosive changes of tracheal epithelium were observed whereas small bronchi and bronchioli exhibited luminal obstructions by mucus plugs, caused by hypersecretion of goblet cells. Using histochemical methods degenerative changes of bronchiolar epithelium were observed.
Eckert
H
H
Forschungsinstitut für Lungenkrankheiten und Tuberkulose, Berlin-Buch/DDR.
Danzmann
E
E
Voigt
H
H
Oddoy
A
A
Merker
G
G
Harzendorf
E
E
Bomm
M
M
Noack
K
K
Ritzau
E
E
D000818:Animals; D001980:Bronchi / Q000473:pathology; D004285:Dogs; D004848:Epithelium / Q000473:pathology; D005260:Female; D006612:High-Frequency Ventilation; D008168:Lung / Q000473:pathology*; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology; D011663:Pulmonary Surfactants / Q000378:metabolism; D014132:Trachea / Q000473:pathology*
D011663:Pulmonary Surfactants
Tierexperimentelle Untersuchungen zu morphologischen Veränderungen an Trachea und Lunge bei Hochfrequenzbeatmung.