title: Collection of analytical data for benzodiazepines and benzophenones.
abstract: On April 1st, 1986, amendments were made to Schedule 2 to the Misuse of Drugs Act 1971 such that 33 benzodiazepines became controlled as Class C drugs in the U.K. An analytical database has been prepared to aid the detection and identification of controlled benzodiazepines. Chromatographic properties have been measured including gas chromatography (GC) retention index values, high-performance liquid chromatography (HPLC) capacity factors and thin-layer chromatography (TLC) RF x 100 values. UV spectroscopic and mass spectrometric (MS) data have also been recorded. Analytical data (GC, TLC and MS) are also presented for benzophenones which were produced by acid hydrolysis of the parent benzodiazepines.
authors.affiliation: Central Research Establishment, Home Office Forensic Science Service, Reading, Berkshire, U.K.
authors.forename: M
authors.initials: M
authors.lastname: Japp
authors.forename: K
authors.initials: K
authors.lastname: Garthwaite
authors.forename: A V
authors.initials: AV
authors.lastname: Geeson
authors.forename: M D
authors.initials: MD
authors.lastname: Osselton
mesh_terms: D001569:Benzodiazepines / Q000032:analysis*; D001577:Benzophenones / Q000032:analysis*; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D013058:Mass Spectrometry; D008970:Molecular Weight; D013056:Spectrophotometry, Ultraviolet
chemical_list: D001577:Benzophenones; D001569:Benzodiazepines