title: Stepwise detoxification from cocaine. A promising regimen.
abstract: Cocaine dependence may not respond to behavioral and self-help treatment because of alterations in neurochemistry, particularly the catecholamine system. Thus, medical detoxification using a stepwise approach and several different therapeutic agents is often needed to assist the patient in achieving a cocaine-free state. An outpatient regimen includes regular clinic attendance, urine testing, education of patient and family, psychological evaluation, and a three- to four-week counseling program. Continued use of medication may be advisable for four to six months. Re-treatment is encouraged if relapse occurs.
authors.affiliation: Community Health Projects Medical Group, Research and Education Division, West Covina, CA 91790.
authors.forename: F
authors.initials: F
authors.lastname: Tennant
authors.forename: M L
authors.initials: ML
authors.lastname: Berman
mesh_terms: D000293:Adolescent; D000328:Adult; D000547:Amantadine / Q000008:administration & dosage; D001971:Bromocriptine / Q000008:administration & dosage; D003042:Cocaine / Q000009:adverse effects; D003891:Desipramine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy; D019966:Substance-Related Disorders / Q000188:drug therapy*; D014364:Tryptophan / Q000008:administration & dosage; D014443:Tyrosine / Q000008:administration & dosage
chemical_list: D001971:Bromocriptine; D014443:Tyrosine; D007980:Levodopa; D014364:Tryptophan; D000547:Amantadine; D003042:Cocaine; D003891:Desipramine