Gene for lipoamide dehydrogenase maps to human chromosome 7.
The gene for lipoamide dehydrogenase (LD) has been assigned to human chromosome 7 based on filter hybridization analysis of genomic DNA from rodent-human somatic cell hybrids using a cDNA probe for human LD. No indication of multiple copies of the gene was found, in accordance with previous evidence that LD in the pyruvate, alpha-ketoglutarate, and branched chain alpha-ketoacid dehydrogenase complexes is genetically as well as biochemically identical.
Otulakowski
G
G
Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Robinson
B H
BH
Willard
H F
HF
D002874:Chromosome Mapping; D002897:Chromosomes, Human, Pair 7; D008058:Dihydrolipoamide Dehydrogenase / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D009693:Nucleic Acid Hybridization
D008058:Dihydrolipoamide Dehydrogenase