[Effectiveness of combined radiotherapy of patients with stage IB cervical cancer using gamma therapy with an AGAT-B catheter device].
The results of combined radiation therapy of 134 patients with cervical cancer, stage IB, using intracavitary gamma-beam therapy on the Agat-B unit were analyzed. The frequency of late radiation complications after treatment in the period of 1-5 yrs. was analyzed. The most common complications were necroepithelitis (9.7 +/- 2.6%), cystitis was less common (7.5 +/- 1.8%) as well as proctitis (1.5 +/- 1.0%). Therapeutic efficacy was assessed by primary tumor resorption, the presence of recurrences and metastases, and patients' survival. The cure rate of a primary focus was attained in 100%. Four patients died of the main disease. By the time of recurrence either osseous, organ or lymphogenic metastases were noted in them. Locoregional recurrences were undetectable in either of the patients. Radiation-induced tumors were not detected in them, either. The 5-year survival rate was 96.8%. A conclusion was made that the above method was very effective for therapy of patients with cervical cancer, stage IB and as such, should be a method of choice for them.
Vishnevskaia
E E
EE
Furmanchuk
L A
LA
D000328:Adult; D000368:Aged; D001918:Brachytherapy / Q000295:instrumentation; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D003556:Cystitis / Q000209:etiology; D004760:Enterocolitis / Q000209:etiology; D005260:Female; D006801:Humans; D007970:Leukopenia / Q000209:etiology; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011349:Proctitis / Q000209:etiology; D011832:Radiation Injuries / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*
Effektivnost' sochetannoĭ luchevoĭ terapii s ispol'zovaniem vnutripolostnoĭ gamma-terapii na shlangovom apparate AGAT-V u bol'nykh rakom sheĭki matki IB stadii.