title: Some effects and properties of Duvernoy's gland secretion from Hypsiglena torquata texana (Texas night snake).
abstract: The Texas night snake (Hypsiglena torquata texana), a small opisthoglyphic colubrid snake, produces a Duvernoy's secretion which has a relatively low lethal toxicity for mice, but produces pain, hemorrhage, and oedema at the site of injection. The subcutaneous LD50 of Hypsiglena torquata texana Duvernoy's secretion in Swiss-Webster mice was 26 mg/kg. Local hemorrhaging occurred at doses as low as 2.0 micrograms/mouse, while marked hemorrhage and oedema resulted at doses greater than 200 micrograms/mouse. The dry secretion contained 77% protein, and SDS-PAGE electrophoresis revealed the presence of seven major proteinaceous components.
authors.affiliation: Department of Zoology, Washington State University, Pullman 99164-4220.
authors.forename: D K
authors.initials: DK
authors.lastname: Vest
mesh_terms: D000818:Animals; D005088:Exocrine Glands / Q000378:metabolism*; D006470:Hemorrhage / Q000139:chemically induced; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D012910:Snake Venoms / Q000633:toxicity*; D012911:Snakes / Q000502:physiology*
chemical_list: D012910:Snake Venoms