title: [Effect of bombesin on the frequency of slow potentials of the smooth muscles of the gastrointestinal tract and migrating myoelectric complex].
abstract: In dogs with electrodes implanted in the smooth muscle wall of the stomach, small intestine and colon, i.v. administration of bombesin (50, 100, 200 and 300 ng/kg) during the 2nd phase of the migrating myoelectric complex (MMC) increased the dose-dependent frequency of slow potential in the small intestine and stomach leaving unchanged the frequency of slow potentials in the colon. Single doses of 50 or 200 ng/kg bombesin during the 2nd phase of the MMC caused a short-term inhibition of the gastric and intestinal spike activity followed by its increase, the active period of the MMC being prolonged.
authors.forename: N I
authors.initials: NI
authors.lastname: Kortezova
authors.forename: S L
authors.initials: SL
authors.lastname: Mileva
authors.forename: V A
authors.initials: VA
authors.lastname: Bagaev
authors.forename: M P
authors.initials: MP
authors.lastname: Papazova
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D001839:Bombesin / Q000494:pharmacology*; D004064:Digestive System / Q000187:drug effects*; D004068:Digestive System Physiological Phenomena; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology
chemical_list: D001839:Bombesin
vernacular_title: Vliianie bombezina na chastotu medlennykh potentialov gladkikh myshts zheudochno-kishechnogo trakta i migriruiushchiĭ mioélektricheskiĭ kompleks.