title: [Effect of succinic acid on blood coagulability and the catecholamine balance].
abstract: A single administration of succinic acid was shown to cause a dose-dependent decrease of the blood coagulability in rats. Seven-day administration of succinic acid (50 mg/kg) resulted in a distinct increase of the blood coagulability, an accumulation of adrenaline in the heart and adrenal gland tissues. Hypercoagulation was noted on the 5th day after withdrawal of succinic acid (50 and 200 mg/kg).
authors.forename: A A
authors.initials: AA
authors.lastname: Nikulin
authors.forename: S I
authors.initials: SI
authors.lastname: Khrapova
authors.forename: E A
authors.initials: EA
authors.lastname: Tebiakina
authors.forename: A K
authors.initials: AK
authors.lastname: Rachkov
authors.forename: M V
authors.initials: MV
authors.lastname: Semenchenko
mesh_terms: D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001808:Blood Vessels / Q000187:drug effects; D002395:Catecholamines / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008297:Male; D009206:Myocardium / Q000378:metabolism; D011898:Ranidae; D051381:Rats; D013386:Succinates / Q000494:pharmacology*; D019802:Succinic Acid; D013997:Time Factors
chemical_list: D002395:Catecholamines; D013386:Succinates; D019802:Succinic Acid
vernacular_title: K voprosu o vliianii iantarnoĭ kisloty na svertyvaemost' krovi i balans katekholaminov.