[The role of intracortical inhibition in forming homo- and heterosensory interaction on the neurons of the sensorimotor cortex in kittens].
The development of the homo- and heterosensory interaction on the sensorimotor cortex neurons was studied in anaesthesized and immobilized kittens of 3 age groups (12-30 days; 31-47 days; 2-4 months before and after the picrotoxin application. For the studied time intervals (100, 200, 300 ms) the insignificant suppression of response to the second stimulus is observed in a small part of the youngest kitten neurons. The picrotoxin application elicited only a rise in the background activity. In the middle and oldest kitten groups it is noted in the neurons which showed decreasing or blocking the responses to the testing stimuli, especially for the interval of 100 ms. The dynamics of the heterosensory interaction and the picrotoxin application influence become gradually the same in the adult animals. On the basis of the obtained results a question is discussed about the development of the inhibition mechanisms and their participation in the organization of the homo- and heterosensory interaction in the early postnatal ontogeny.
Vasil'eva
L A
LA
Zotova
E G
EG
Aseev
D Iu
DIu
D000161:Acoustic Stimulation; D000375:Aging / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D009044:Motor Cortex / Q000187:drug effects / Q000502:physiology*; D009433:Neural Inhibition / Q000187:drug effects; D009475:Neurons, Afferent / Q000187:drug effects / Q000502:physiology*; D010852:Picrotoxin / Q000494:pharmacology; D013997:Time Factors
D010852:Picrotoxin
Rol' vnutrikortikal'nogo tormozheniia v formirovanii gomo- i geterosensornogo vzaimodeĭstviia na neĭronakh sensomotornoĭ kory u kotiat.