[Evaluation of the functional state of the liver using the blood enzyme spectrum after hemosorption for burn toxemia].
A rate of blood serum toxicity was markedly increased beginning from the second day after thermic burns of dogs. At the same time, statistically distinct alterations were found in liver tissue specific enzymes activity demonstrating the necrotic impairments of liver tissue and cytolysis of hepatocytes. After hemosorption the rate of blood serum toxicity was steadily decreased, the enzymatic spectrum and leukocyte index of intoxication were normalized in blood serum, which appears to relate to lowering of destructive processes in liver tissue and to maintaining of hepatocytes functional activity.
Mikaelian
N P
NP
Il'ina
Z I
ZI
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D002056:Burns / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D004796:Clinical Enzyme Tests; D004285:Dogs; D004798:Enzymes / Q000097:blood*; D006464:Hemoperfusion; D008099:Liver / Q000503:physiopathology*; D014115:Toxemia / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy
D004798:Enzymes; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Otsenka funktsional'nogo sostoianiia pecheni po fermentnomu spektru krovi posle gemosorbtsii v sviazi s ozhogovoĭ intoksikatsieĭ.