[Early results of alternating treatment of multiple sclerosis with immunosuppressive and immunomodulating drugs].
A group of 18 patients with clinically certain diagnosis of multiple sclerosis were treated alternate with prednisone and Decaris (levamisole). The results were compared with those in a control group of 18 cases with similar initial clinical parameters treated exclusively with prednisone during exacerbations of the disease. Alternating treatment with the mild immunosuppressant, prednisone, and with the immunomodulating drug Decaris caused a statistically significant reduction in the number of exacerbations of multiple sclerosis, however, the effect of this treatment on the natural history of the disease could not have been established in view of the short period of follow-up.
Wender
M
M
Katedry Neurologii AM w Poznaniu.
Tokarz-Kupczyk
E
E
Mularek
O
O
D000276:Adjuvants, Immunologic; D000328:Adult; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents; D007978:Levamisole / Q000008:administration & dosage*; D008297:Male; D009103:Multiple Sclerosis / Q000188:drug therapy* / Q000276:immunology; D011241:Prednisone / Q000008:administration & dosage*; D013997:Time Factors
D000276:Adjuvants, Immunologic; D007166:Immunosuppressive Agents; D007978:Levamisole; D011241:Prednisone
Wczesne wyniki leczenia naprzemiennego SM lekami immunosupresyjnymi i immunomodulacyjnymi.