title: [Analysis of trace elements and crystalline formations in the sputum in bronchial asthma].
abstract: The content of sputum trace elements was investigated in 12 patients with bronchial asthma (BA). The presence of Na, K, Ca, P, Mg, Si, Sn, Fe, Mn, Cu, Ti, Ag, Al, V, B was revealed. The absence of Zn and high levels of Ca and Sn were observed. Multiple crystalline Ca precipitates (phosphates, carbonates and oxalates) were found in the sputum of 56 BA patients. Ammonium urate and uric acid were also revealed. The author supposed disturbance of calcium homeostasis and purine metabolism in BA patients, involvement of the detected crystalline formations in the pathogenesis of BA obstruction bronchospasm and deterioration of sputum rheological properties.
authors.forename: V T
authors.initials: VT
authors.lastname: Volkov
mesh_terms: D000328:Adult; D000368:Aged; D001249:Asthma / Q000378:metabolism*; D003460:Crystallization; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008875:Middle Aged; D013057:Spectrum Analysis; D013183:Sputum / Q000032:analysis* / Q000378:metabolism; D014131:Trace Elements / Q000032:analysis*
chemical_list: D014131:Trace Elements
vernacular_title: Analiz mikroélementov i kristallicheskikh obrazovaniĭ v mokrote pri bronkhial'noĭ astme.