title: Lymphocyte localization in lymph nodes of swine: changes induced by lactation.
abstract: Localization patterns of lymphocytes taken from mammary, ileal mesenteric, or prefemoral lymph nodes of pubescent or lactating swine were examined. Lymphocyte suspensions were prepared from surgically excised lymph nodes, labeled with 51chromium, and infused back into the donors. Eighteen hours later, pigs were killed, and lymph nodes from six different regions examined for radiolabel. The greatest concentrations of labeled cells were consistently recovered from mesenteric and bronchial lymph nodes, with lesser concentrations recovered from mammary and peripheral nodes. This occurred regardless of origin of the infused cells, and in both pubescent and lactating pigs. Although localization patterns were similar, the total recovery of infused mammary node cells in the six nodes examined was consistently higher in lactating than in pubescent pigs. In contrast, recovery of infused mesenteric node cells was lower in lactating than in pubescent pigs.
authors.affiliation: U.S. Department of Agriculture, National Animal Disease Center, Ames, Iowa 50010.
authors.forename: J A
authors.initials: JA
authors.lastname: Harp
authors.forename: H W
authors.initials: HW
authors.lastname: Moon
mesh_terms: D000818:Animals; D002452:Cell Count; D002465:Cell Movement; D005260:Female; D007774:Lactation / Q000276:immunology*; D008198:Lymph Nodes / Q000166:cytology* / Q000276:immunology; D008214:Lymphocytes / Q000166:cytology* / Q000276:immunology; D008321:Mammary Glands, Animal / Q000276:immunology; D011247:Pregnancy; D013552:Swine