title: The effects of sensory stimulation on the free amino acid pool of the developing brain.
abstract: Developing chicks were subjected to three different paradigmata of sensory stimulation, and the effects on the free amino acid concentrations in the blood and in various brain regions were monitored. The free amino acid pool of individual brain regions was found to be affected in a treatment- and age-specific manner. The increased neuronal activity resulting from sensory stimulation seems to affect intrinsic factors involved in the regulation of the free amino acid pool, most likely via modulations of the rate of metabolization of individual amino acids and/or of the rate of synthesis and degradation of individual proteins in certain brain regions.
authors.affiliation: Max-Planck-Institut für experimentelle Medizin Forschungsstelle Neurochemie, Göttingen, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Huether
authors.forename: V
authors.initials: V
authors.lastname: Neuhoff
mesh_terms: D000344:Afferent Pathways / Q000378:metabolism / Q000502:physiology; D000367:Age Factors; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D002642:Chick Embryo; D009475:Neurons, Afferent / Q000378:metabolism* / Q000502:physiology; D010775:Photic Stimulation; D012054:Reinforcement, Psychology
chemical_list: D000596:Amino Acids