title: Anti AChR antibody: relevance to diagnosis and clinical aspects of myasthenia gravis.
abstract: 227 sera from myasthenic patients were tested for the presence of anti-AChR antibodies (anti-AChR Abs) by mean of a fetal calf receptor (Fc-AChR); 73.5% of cases proved positive with this method. Significant correlations were found between presence of anti-Fc-AChr Abs and various clinical aspects such as: clinical stage and duration of disease; moreover significantly higher than the median titers were found among younger patients (i.e. age less than 40 yrs).
authors.affiliation: Servizio di Studio e Cura delle Malattie Neuromuscolari, Istituto Neurologico C. Besta, Milano.
authors.forename: R
authors.initials: R
authors.lastname: Mantegazza
authors.forename: D
authors.initials: D
authors.lastname: Pareyson
authors.forename: F
authors.initials: F
authors.lastname: Baggi
authors.forename: P
authors.initials: P
authors.lastname: Romagnoli
authors.forename: D
authors.initials: D
authors.lastname: Peluchetti
authors.forename: A
authors.initials: A
authors.lastname: Sghirlanzoni
authors.forename: F
authors.initials: F
authors.lastname: Cornelio
mesh_terms: D000328:Adult; D000367:Age Factors; D001323:Autoantibodies / Q000032:analysis*; D006801:Humans; D007159:Immunologic Tests; D009157:Myasthenia Gravis / Q000175:diagnosis* / Q000276:immunology; D011950:Receptors, Cholinergic / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D011950:Receptors, Cholinergic