title: [Dynamics of the renal excretion of glycosaminoglycans as affected by thyroid therapy of hypothyroidism].
abstract: The state of renal excretion of glycosaminoglycans (GAG) was investigated in 15 patients with hypothyrosis of various degree of gravity before and during thyroid therapy. A raised level of GAG excretion with urine reflecting excessive GAG tissue accumulation was revealed. A degree of elevation was unrelated to a gravity of disease and grew with a period of disease. Thyroid therapy considerably increased GAG renal excretion, particularly in patients with a longer period of disease. A GAG level in daily urine can be used as an additional diagnostic criterion in hypothyrosis and the time course of GAG can serve for assessment of therapeutic efficacy.
authors.forename: A N
authors.initials: AN
authors.lastname: Nazarov
authors.forename: F M
authors.initials: FM
authors.lastname: Egart
authors.forename: T A
authors.initials: TA
authors.lastname: Bobrovskaia
authors.forename: E I
authors.initials: EI
authors.lastname: Daĭkhin
authors.forename: V T
authors.initials: VT
authors.lastname: Sugoniaeva
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004338:Drug Combinations; D005260:Female; D006025:Glycosaminoglycans / Q000652:urine*; D006728:Hormones / Q000008:administration & dosage*; D006801:Humans; D007037:Hypothyroidism / Q000188:drug therapy / Q000652:urine*; D008297:Male; D008875:Middle Aged; D013607:Tablets; D013963:Thyroid Hormones / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D006025:Glycosaminoglycans; D006728:Hormones; D013607:Tablets; D013963:Thyroid Hormones
vernacular_title: Dinamika pochechnoĭ ékskretsii glikozaminoglikanov pod vliianiem tireoidnoĭ terapii pri gipotireoze.