title: Recombination within the class III region by a double cross over event.
abstract: Analysis of class I, class II, and class III gene products of the human MHC in a Caucasoid family with four children gave evidence for a double crossing over event in monozygotic twins between the C2, Bf/C4A, C4B gene loci. In view of the small genetic distance between C2 and C4, a point mutation within the Bf locus must be considered alternatively.
authors.affiliation: Institute of Forensic Medicine, School of Medicine (Charité), Humboldt University, Berlin, GDR.
authors.forename: M
authors.initials: M
authors.lastname: Rose
authors.forename: G R
authors.initials: GR
authors.lastname: Menzel
authors.forename: G
authors.initials: G
authors.lastname: Geserick
authors.forename: G
authors.initials: G
authors.lastname: Doxiadis
authors.forename: H
authors.initials: H
authors.lastname: Grosse-Wilde
authors.forename: M
authors.initials: M
authors.lastname: Mukaida
authors.forename: A
authors.initials: A
authors.lastname: Rackwitz
mesh_terms: D003434:Crossing Over, Genetic; D005260:Female; D006680:HLA Antigens / Q000145:classification; D006801:Humans; D008285:Major Histocompatibility Complex; D008297:Male; D009154:Mutation; D011995:Recombination, Genetic
chemical_list: D006680:HLA Antigens