title: Thyroid carcinoma masquerading as a solitary benign hyperfunctioning nodule.
abstract: Focal hot nodules on iodine thyroid images are associated with an exceedingly low incidence of malignancy. Most previously reported hot carcinomas represent the coexistence of small malignancies in or adjacent to a benign hot lesion. Described here is a 3-cm papillary carcinoma that fulfilled the criteria for benignancy on Tc-99m and I-123 imaging. Coincidental carcinoma within a benign lesion was excluded by detailed scintigraphic-pathologic correlation of the tumor. The implications of this case on the management of the solitary hot nodule are discussed and the literature reviewed.
authors.affiliation: Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
authors.forename: M P
authors.initials: MP
authors.lastname: Sandler
authors.forename: B
authors.initials: B
authors.lastname: Fellmeth
authors.forename: K E
authors.initials: KE
authors.lastname: Salhany
authors.forename: J A
authors.initials: JA
authors.lastname: Patton
mesh_terms: D000368:Aged; D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D011877:Radionuclide Imaging; D013667:Technetium; D013959:Thyroid Diseases / Q000000981:diagnostic imaging*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D007457:Iodine Radioisotopes; D013667:Technetium