title: Evaluation of preoperative blood tests for predicting deep vein thrombosis after total hip replacement.
abstract: Determinations of the total calcium content and aggregability of the platelets as well as tests of coagulation and fibrinolysis were carried out on 93 patients before undergoing total hip replacement. All patients received low dose heparin, solely or combined with dihydroergotamine. Twenty-six patients developed deep vein thrombosis (DVT) detected by the labelled fibrinogen uptake test and confirmed by ascending phlebography. Only a few tests, among them the total calcium content of platelets, showed a statistical difference between the patients who subsequently developed DVT and those who did not. Combination of several tests by a multivariate statistical analysis programme proved to have more predictive value than the analysis of single tests.
authors.affiliation: Institute of Pathological Biochemistry, Medical Academy of Erfurt.
authors.forename: K
authors.initials: K
authors.lastname: Mindner
authors.forename: I
authors.initials: I
authors.lastname: Bergmann
authors.forename: G
authors.initials: G
authors.lastname: Sturm
authors.forename: H
authors.initials: H
authors.lastname: Liedloff
authors.forename: P
authors.initials: P
authors.lastname: Hindersin
authors.forename: W
authors.initials: W
authors.lastname: Gleiser
authors.forename: U
authors.initials: U
authors.lastname: Till
authors.forename: G
authors.initials: G
authors.lastname: Vogel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001780:Blood Coagulation Tests; D004087:Dihydroergotamine / Q000627:therapeutic use; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D011379:Prognosis; D013924:Thrombophlebitis / Q000097:blood / Q000209:etiology*
chemical_list: D004087:Dihydroergotamine; D006493:Heparin