title: Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22.
abstract: Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.
authors.affiliation: Eleanor Roosevelt Institute for Cancer Research, Denver, Colorado 80206.
authors.forename: F T
authors.initials: FT
authors.lastname: Kao
authors.forename: J
authors.initials: J
authors.lastname: Hartz
authors.forename: R
authors.initials: R
authors.lastname: Horton
authors.forename: Y
authors.initials: Y
authors.lastname: Nemerson
authors.forename: S D
authors.initials: SD
authors.lastname: Carson
mesh_terms: D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D006801:Humans; D009693:Nucleic Acid Hybridization; D013925:Thromboplastin / Q000235:genetics*
chemical_list: D013925:Thromboplastin