Medulloblastoma in infancy associated with omphalocele, malrotation of the intestine, and extrophy of the bladder.
A successfully treated case of infantile medulloblastoma is presented that was associated with omphalocele, malrotation of the intestine, and extrophy of the bladder. A 5-month-old boy was admitted due to disturbance of consciousness and was diagnosed by computed tomography as having a medulloblastoma. Ventricular drainage, subduralperitoneal shunt, and removal of the tumor were performed, and postoperatively radiation therapy was administrated with 4,000 rad to the whole brain. He was discharged in good condition and no evidence of recurrence was observed at the 14th post-operative month. Medulloblastomas associated with congenital anomaly of the abdomen have been only rarely reported. The authors postulate that between the second and third month of gestation an intrinsic or extrinsic factor may have caused the development of the medulloblastoma, as well as anomalies of the abdomen such as omphalocele, malrotation of the intestine, and extrophy of the bladder.
Ogasawara
H
H
Department of Neurosurgery, Shimane Prefectural Central Hospital, Izumo, Japan.
Inagawa
T
T
Yamamoto
M
M
Kamiya
K
K
Yano
T
T
Utsunomiya
H
H
D002528:Cerebellar Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D002533:Cerebral Angiography; D006554:Hernia, Umbilical / Q000150:complications* / Q000601:surgery; D006801:Humans; D007223:Infant; D007422:Intestines / Q000002:abnormalities* / Q000601:surgery; D008297:Male; D008527:Medulloblastoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed; D001743:Urinary Bladder / Q000002:abnormalities*