title: Erythropoietic protoporphyria exacerbated by oral iron therapy.
abstract: Four patients with erythropoietic protoporphyria (EPP) are reported, in whom oral iron produced clear-cut clinical and biochemical deterioration. This suggests that there are two biochemically and genetically distinct sub-groups of EPP patients distinguished by their dramatically different response to oral iron.
authors.affiliation: Department of Dermatology, Leicester Royal Infirmary, London, U.K.
authors.forename: A
authors.initials: A
authors.lastname: Milligan
authors.forename: R A
authors.initials: RA
authors.lastname: Graham-Brown
authors.forename: I
authors.initials: I
authors.lastname: Sarkany
authors.forename: H
authors.initials: H
authors.lastname: Baker
mesh_terms: D000328:Adult; D000747:Anemia, Hypochromic / Q000188:drug therapy / Q000209:etiology; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D007501:Iron / Q000009:adverse effects* / Q000097:blood; D010787:Photosensitivity Disorders / Q000097:blood / Q000139:chemically induced*; D011164:Porphyrias / Q000150:complications; D011524:Protoporphyrins / Q000097:blood; D012871:Skin Diseases / Q000150:complications
chemical_list: D011524:Protoporphyrins; D005293:Ferritins; D007501:Iron