title: Preliminary X-ray analysis of crystals of murine adenosine deaminase.
abstract: We have obtained single crystals of a cloned mammalian adenosine deaminase (Mr = 41,000), a key enzyme in purine degradation and in normal development of the immune system, that are suitable for high-resolution structural analysis. The crystals belong to the space group C2 with unit cell parameters a = 101.68 A (1 A = 0.1 nm), b = 94.38 A, c = 85.51 A, and beta = 96.54 degrees. The asymmetric unit contains two enzyme molecules.
authors.affiliation: Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030.
authors.forename: D K
authors.initials: DK
authors.lastname: Wilson
authors.forename: F B
authors.initials: FB
authors.lastname: Rudolph
authors.forename: M L
authors.initials: ML
authors.lastname: Harrison
authors.forename: R E
authors.initials: RE
authors.lastname: Kellems
authors.forename: F A
authors.initials: FA
authors.lastname: Quiocho
mesh_terms: D000243:Adenosine Deaminase; D000818:Animals; D051379:Mice; D009700:Nucleoside Deaminases; D014961:X-Ray Diffraction
chemical_list: D009700:Nucleoside Deaminases; D000243:Adenosine Deaminase