Unexpected red cell antibodies in thalassemic children.
Nineteen of the 632 (3%) children with homozygous beta-thal and beta thal/Hb E developed alloantibodies to red cell antigens, primarily as a result of repeated transfusion. There were eight cases of anti-E, four cases of anti-E+, and two cases of anti-Le(a + b) antibodies. The low incidence rate in these patients is probably due to acquired tolerance.
Fongsatitkul
L
L
Division of Blood Bank, Chiang Mai University, Thailand.
Bannawat
U
U
Sanguansermsri
T
T
Kulapongs
P
P
D002648:Child; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D007518:Isoantibodies / Q000032:analysis*; D013789:Thalassemia / Q000276:immunology*; D065227:Transfusion Reaction
D007518:Isoantibodies