title: Occult thyroid dysfunction in patients with refractory depression.
abstract: Assessment of metabolic rate was useful in evaluating refractory depression in six of 15 women. Five of the six had normal levels of T3 and T4; however, each had an elevated thyrotropin-stimulating hormone level or a low metabolic rate. The depressions responded to medication with thyroid hormone.
authors.affiliation: Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY.
authors.forename: G R
authors.initials: GR
authors.lastname: Gewirtz
authors.forename: D
authors.initials: D
authors.lastname: Malaspina
authors.forename: J A
authors.initials: JA
authors.lastname: Hatterer
authors.forename: S
authors.initials: S
authors.lastname: Feureisen
authors.forename: D
authors.initials: D
authors.lastname: Klein
authors.forename: J M
authors.initials: JM
authors.lastname: Gorman
mesh_terms: D000328:Adult; D001481:Basal Metabolism; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications; D008875:Middle Aged; D013961:Thyroid Gland / Q000503:physiopathology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine