title: Radiotherapy employing three fractions on each of twelve consecutive days.
abstract: In order to achieve the greatest advantage of accelerated hyperfractionated radiotherapy, treatment has been given 3 times each day for 12 consecutive days without a rest period. A total tumour dose of 50.4 Gy was well tolerated in a series of 38 patients with bronchial, head and neck and oesophageal carcinomas. A further 14 patients have now received an elevated dose of 54 Gy, again with satisfactory tolerance. The tumour responses at all these sites have been very promising and further work is proceeding.
authors.affiliation: Regional Radiotherapy and Oncology Centre, Mount Vernon Hospital, Northwood, England.
authors.forename: M I
authors.initials: MI
authors.lastname: Saunders
authors.forename: S
authors.initials: S
authors.lastname: Dische
authors.forename: J F
authors.initials: JF
authors.lastname: Fowler
authors.forename: J
authors.initials: J
authors.lastname: Denekamp
authors.forename: E P
authors.initials: EP
authors.lastname: Dunphy
authors.forename: E
authors.initials: E
authors.lastname: Grosch
authors.forename: D
authors.initials: D
authors.lastname: Fermont
authors.forename: R
authors.initials: R
authors.lastname: Ashford
authors.forename: J
authors.initials: J
authors.lastname: Maher
authors.forename: C
authors.initials: C
authors.lastname: Des Rochers
mesh_terms: D001984:Bronchial Neoplasms / Q000532:radiotherapy; D004938:Esophageal Neoplasms / Q000532:radiotherapy; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage