PAF of biological fluids in disease: IV. Levels in blood in allergic reactions induced by drugs.
In allergic reactions induced by drugs we detected elevated platelet activating factor (PAF) bioactivity in blood and we isolated a substance with activity and chemical characteristics similar to AGEPC (semisynthetic PAF, beef-heart derived PAF). The levels of the circulating substance were about ten times higher than the ones detected in normal subjects.
Lazanas
M
M
University of Athens, Department of Food Chemistry, Greece.
Demopoulos
C A
CA
Tournis
S
S
Koussissis
S
S
Labrakis-Lazanas
K
K
Tsarouhas
X
X
D000328:Adult; D000368:Aged; D002851:Chromatography, High Pressure Liquid; D003888:Desensitization, Immunologic; D004342:Drug Hypersensitivity / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010972:Platelet Activating Factor / Q000097:blood*; D012995:Solubility
D010972:Platelet Activating Factor