Bromocriptine-induced trigeminal neuralgia attacks in a patient with a pituitary tumor.
We describe a patient who suffered from ophthalmic trigeminal neuralgia as an isolated symptom of a noninvasive pituitary tumor. Bromocriptine appeared to provoke the attacks within hours. This provocation could be prevented by domperidone. After adenomectomy, both spontaneous and induced attacks disappeared. Acute transient cell swelling may be the mechanism by which bromocriptine induced the neuralgic attacks.
Ferrari
M D
MD
Department of Neurology, University Hospital, Leiden, The Netherlands.
Haan
J
J
van Seters
A P
AP
D000236:Adenoma / Q000097:blood / Q000150:complications / Q000188:drug therapy; D001971:Bromocriptine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D011388:Prolactin / Q000097:blood; D014277:Trigeminal Neuralgia / Q000097:blood / Q000139:chemically induced / Q000209:etiology*
D001971:Bromocriptine; D011388:Prolactin