title: [Peri-implantation enzymes and mineralization in bone tissue after implantation of bioactive vitroceramic material--a method for biomaterial testing for hard tissue substitutes. 2. Results of studies of vitroceramics and their modification by the admixture of metal oxides].
abstract: The activities of the alkaline and the acid bone phosphatases as well as the concentrations of calcium and phosphorus were measured in the periimplantal tissue of the rat femur bone after implantation of the vitroceramic Ap 40, the metal oxide stabilized vitroceramics Ap 40 A and Ap 40 Z, as well titanium after 2, 10, and 15 weeks. The incorporation of the vitroceramic Ap 40 turns out like a primary bone fracture healing. The implants Ap 40 A and Ap 40 Z are a compromise with a higher stability and the osteogenesis induced effect is preserved, but is belated in contrast to Ap 40.
authors.affiliation: Institut für Klinische Chemie und Hämatologie, Humboldt-Universität zu Berlin.
authors.forename: H
authors.initials: H
authors.lastname: Reichelt
authors.forename: S
authors.initials: S
authors.lastname: Köhler
authors.forename: G
authors.initials: G
authors.lastname: Berger
authors.forename: J
authors.initials: J
authors.lastname: Draffehn
authors.forename: R
authors.initials: R
authors.lastname: Sauer
authors.forename: M
authors.initials: M
authors.lastname: Krenz
authors.forename: H
authors.initials: H
authors.lastname: Wichner
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000535:Aluminum; D000537:Aluminum Oxide; D000818:Animals; D001705:Bioprosthesis; D001842:Bone and Bones / Q000201:enzymology / Q000502:physiology*; D002118:Calcium / Q000032:analysis; D002516:Ceramics; D005269:Femur; D010758:Phosphorus / Q000032:analysis; D051381:Rats; D013329:Structure-Activity Relationship; D014025:Titanium; D015040:Zirconium
chemical_list: C009495:titanium dioxide; D010758:Phosphorus; C031323:bio-vitroceramic AP40; D015040:Zirconium; D000535:Aluminum; D014025:Titanium; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D000537:Aluminum Oxide; C028541:zirconium oxide; D002118:Calcium
vernacular_title: Untersuchungen periimplantärer Enzymaktivitäten und der periimplantären Mineralisation im Knochengewebe nach Implantation bioaktiver vitrokeramischer Materialien--Eine Methode der Biomaterialprüfung für den Hartgewebeersatz. Teil 2: Ergebnisse der Untersuchungen von Vitrokeramen und deren Modifizierungen durch Zusatz von Metalloxiden.