title: [Effect of plant growth regulators, hydrazine derivatives, on the state of the microsomal systems of the liver].
abstract: Hydrazine derivatives (Gidrel, Digidrel and DMMH) at a dose of 1/10 (LD50) inhibit microsomal oxidation, decrease superoxide dismutase activity and activate lipid peroxidation in the rat hepatic microsomes. At the same dose level maleic hydrazide has no effect on the indices studied. The role of superoxide-superoxide dismutase system in the mechanism of microsomal oxidation inhibition by hydrazine derivatives is discussed.
authors.forename: A O
authors.initials: AO
authors.lastname: Koshkarian
authors.forename: E S
authors.initials: ES
authors.lastname: Kocharian
authors.forename: G A
authors.initials: GA
authors.lastname: Aloian
authors.forename: A Kh
authors.initials: AKh
authors.lastname: Avakian
mesh_terms: D000818:Animals; D008054:Lipid Peroxides / Q000096:biosynthesis; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects* / Q000378:metabolism; D009943:Organophosphorus Compounds / Q000633:toxicity*; D010084:Oxidation-Reduction; D010937:Plant Growth Regulators / Q000494:pharmacology*; D051381:Rats; D013268:Stimulation, Chemical; D013386:Succinates / Q000494:pharmacology; D013482:Superoxide Dismutase / Q000378:metabolism
chemical_list: D008054:Lipid Peroxides; D009943:Organophosphorus Compounds; D010937:Plant Growth Regulators; D013386:Succinates; C025731:Hydrel; C037724:dihydrel; D013482:Superoxide Dismutase; C014499:daminozide
vernacular_title: Vliianie reguliatorov rosta rasteniĭ--proizvodnykh gidrazina--na sostoianie mikrosomnykh sistem pecheni.