Mollaret's meningitis. A variant of recurrent hereditary polyserositis, both provoked by metaraminol.
Mollaret's meningitis is a rare condition with a characteristic clinical and cerebrospinal fluid picture. In many ways it resembles recurrent hereditary polyserositis (familial Mediterranean fever) in its natural history, pattern of attacks, and response to colchicine. Association of the two conditions has been reported, so far, in two patients only. In our patient the symptoms of both conditions were induced by a metaraminol provocative infusion. We have previously introduced this as a specific diagnostic and confirmatory test for recurrent hereditary polyserositis. The possibility that the two conditions represent different manifestations of a single disease is therefore strengthened.
Barakat
M H
MH
Department of Medicine, Faculty of Medicine, Kuwait University.
Mustafa
H T
HT
Shakir
R A
RA
D000293:Adolescent; D003078:Colchicine / Q000627:therapeutic use; D010505:Familial Mediterranean Fever / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008297:Male; D008581:Meningitis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D008680:Metaraminol; D012008:Recurrence
D008680:Metaraminol; D003078:Colchicine