title: Comparison of three methods for determination of N-nitrosopyrrolidine in fried dry-cured and pump-cured bacon.
abstract: Three methods, the mineral oil distillation (MOD), the dry column (DC), and a low temperature vacuum distillation (LTVD), for the determination of N-nitrosopyrrolidine in dry-cured and pump-cured bacon were compared. Each method uses the thermal energy analyzer for the determinative step. The coefficients of variation for repeatability were 10.3% (MOD), 7.2% (DC), and 9.1% (LTVD) for the dry-cured bacon study and 8.7% (MOD), 8.5% (DC), and 7.1% (LTVD) for the pump-cured bacon study. The pooled coefficients of variation for between-method reproducibility were 11.8% for the dry-cured bacon and 10.8% for the pump-cured bacon. The pooled coefficients of variation for repeatability were 9.0% for the dry-cured bacon and 8.2% for the pump-cured bacon. These values compare favorably with the values from previous collaborative or validation studies of the individual methods, and the methods can be considered to be equivalent.
authors.affiliation: U.S. Department of Agriculture, Food Safety and Inspection Service, Washington, DC 20250.
authors.forename: A J
authors.initials: AJ
authors.lastname: Malanoski
authors.forename: W J
authors.initials: WJ
authors.lastname: Smith
authors.forename: T
authors.initials: T
authors.lastname: Phillipo
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D003296:Cooking; D005069:Evaluation Studies as Topic; D005519:Food Preservation; D008460:Meat / Q000032:analysis*; D008899:Mineral Oil; D009242:N-Nitrosopyrrolidine / Q000032:analysis*; D009602:Nitrosamines / Q000032:analysis*; D013552:Swine
chemical_list: D009602:Nitrosamines; D008899:Mineral Oil; D009242:N-Nitrosopyrrolidine