Acetylator polymorphism in discoid lupus erythematosus.
Acetylator phenotype was determined, using sulphamethazine, in 37 patients with histologically confirmed discoid lupus erythematosus, who were free from visceral damage, and in 157 normal control subjects. Twenty patients (54%) and 90 control subjects (57.4%) were slow acetylators (p not significant). Acetylator polymorphism appears not to be related to the risk of developing pure cutaneous discoid lupus erythematosus.
Ladero
J M
JM
Department of Medicine, Hospital Universitario San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
Jiménez
L C
LC
Fernández
M J
MJ
Robledo
A
A
D000107:Acetylation; D000328:Adult; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000235:genetics / Q000378:metabolism*; D008297:Male; D010641:Phenotype; D013030:Spain