[Maculopapular exanthema during diltiazem therapy].
A maculopapular exanthema developed in a 60-year-old man with coronary heart disease while being treated for angina with the calcium antagonist diltiazem. Epicutaneous and scratch tests were positive, both for the immediate type (type I) and the delayed type (type IV), proving that the drug had caused the allergic reaction. The exanthema quickly disappeared once the drug had been discontinued. Anti-anginal treatment was continued without further complications with nifedipine.
Hammentgen
R
R
Medizinische Universitätsklinik, Innere Medizin-Kardiologie, Bonn.
Lutz
G
G
Köhler
U
U
Nitsch
J
J
D000787:Angina Pectoris / Q000150:complications / Q000188:drug therapy; D004110:Diltiazem / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology / Q000473:pathology; D005076:Exanthema / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000209:etiology / Q000473:pathology; D006969:Hypersensitivity, Immediate / Q000209:etiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
D004110:Diltiazem
Makulopapulöses Exanthem bei Diltiazem-Therapie.