title: [Etiology and pathogenesis of synovitis villonodosa pigmentosa].
abstract: Articular pigmented villonodular synovitis is a benign synovial disease of unknown etiology. It is a proliferative disorder of the synovium that can involve the joints, tendon sheaths, and bursae. There is a predilection for involvement of the lower extremities, particularly the knees. There are two histologically similar lesions of pigmented villonodular synovitis: "nodular" and "diffuse" pigmented villonodular tenosynovitis. The typical clinical course consists of progressive and painful swelling of the involved joint. Cystic erosions without sclerosis and invasion of adjacent bone from intra-articular synovial lesions are the typical roentgenographic manifestations. The surgical treatment of the lesions is discussed. A review of the literature is given and our own material on 47 patients is presented to illustrate the different features of the disease.
authors.affiliation: Orthopädische Universitätsklinik Balgrist, Zürich.
authors.forename: A
authors.initials: A
authors.lastname: Imhoff
authors.forename: A
authors.initials: A
authors.lastname: Schreiber
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006621:Hip Joint / Q000473:pathology; D006801:Humans; D007595:Joint Prosthesis; D007719:Knee Joint / Q000473:pathology; D008297:Male; D008875:Middle Aged; D000074402:Synovectomy; D013585:Synovitis / Q000473:pathology*; D013586:Synovitis, Pigmented Villonodular / Q000473:pathology* / Q000601:surgery
vernacular_title: Zur Atiologie und Pathogenese der Synovitis villonodosa pigmentosa.