title: [Radiotherapy of testicular seminoma. Stages I and II A, B].
abstract: From June 1977 through June 1987, 46 patients (36 evaluable) affected by stage I and II non-bulky testicular seminoma were treated with postoperative telecobaltotherapy (TCT). In stage I seminomas, radiotherapy was extended to the omolateral iliac and the para-aortic areas (total dose: 30 Gy over 4 weeks). In stage II seminomas, the subdiaphragmatic lymph nodes were irradiated with 40-45 Gy over 5-6 weeks; after an interval of one month the subdiaphragmatic lymph nodes were irradiated again with a total dose of 25 Gy over 3.5 weeks. Minimal follow-up lasted two years and maximum ten years (average: 5.5). Two (5.5%) recurrences occurred, but salvage radiotherapy and salvage chemotherapy respectively allowed a complete permanent remission. One patient died from a different neoplasia with no evidence of testicular involvement. The 5-year actuarial survival is 96.6 +/- 3.4. In 20% of the patients the side effects were nausea and/or vomiting, easily controlled. No late complications were observed.
authors.affiliation: Unità Organica di Oncologia Radioterapica, Policlinico, Perugia.
authors.forename: P
authors.initials: P
authors.lastname: Latini
authors.forename: C
authors.initials: C
authors.lastname: Aristei
authors.forename: E
authors.initials: E
authors.lastname: Maranzano
authors.forename: F
authors.initials: F
authors.lastname: Checcaglini
authors.forename: B M
authors.initials: BM
authors.lastname: Panizza
authors.forename: E
authors.initials: E
authors.lastname: Perrucci
authors.forename: M C
authors.initials: MC
authors.lastname: Bellucci
mesh_terms: D000328:Adult; D000368:Aged; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004407:Dysgerminoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009919:Orchiectomy; D011867:Radioisotope Teletherapy; D013736:Testicular Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Radioterapia del seminoma testicolare. Stadio I e II A, B.