Corynebacterium aquaticum infection in a patient with chronic granulomatous disease.
Patients with chronic granulomatous disease are uniquely susceptible to infection with catalase-producing bacteria. Staphylococcus aureus, Klebsiella, Escherichia coli and Serratia marcescans are common infecting organisms. A 17-month-old boy with Corynebacterium aquaticum bacteremia is reported. This is only the third documented infection with this non-JK diphtheroid and the first case infection in a patient with chronic granulomatous disease. It is likely that our patient's underlying immune defect predisposed him to infection with this unusual, catalase-producing organism. Although these bacteria are common contaminants and rarely infecting agents, true infection should be considered in patients with chronic granulomatous disease from whom a diphtheroid is isolated.
Kaplan
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Department of Pediatrics, University of North Carolina, Chapel Hill 27514.
Israel
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F
D003352:Corynebacterium / Q000302:isolation & purification; D003354:Corynebacterium Infections / Q000209:etiology* / Q000382:microbiology; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D018805:Sepsis / Q000209:etiology*