title: [Congenital intrinsic factor deficiency. Apropos of 3 cases in a sibship].
abstract: Three familial cases of congenital intrinsic factor deficiency are reported: the stress is put on the interest of gastric investigations and especially of the quantity of intrinsic factor in the gastric juice when investigating megaloblastic anemia due to vitamin B12 deficiency. The study of the level of intrinsic factor in the gastric juice is proposed as a test for identifying carriers.
authors.affiliation: Service d'Hépato-Gastro-Entérologie Infantile, Hôpital E.-Herriot, Lyon.
authors.forename: I
authors.initials: I
authors.lastname: Loras-Duclaux
authors.forename: B
authors.initials: B
authors.lastname: Descos
authors.forename: G
authors.initials: G
authors.lastname: Souillet
authors.forename: A
authors.initials: A
authors.lastname: Lachaux
authors.forename: P
authors.initials: P
authors.lastname: Badinand
authors.forename: N
authors.initials: N
authors.lastname: Montagnon
authors.forename: Y
authors.initials: Y
authors.lastname: Minaire
authors.forename: M
authors.initials: M
authors.lastname: Hermier
mesh_terms: D000748:Anemia, Macrocytic / Q000151:congenital*; D000749:Anemia, Megaloblastic / Q000151:congenital* / Q000235:genetics; D002675:Child, Preschool; D005260:Female; D005750:Gastric Juice / Q000032:analysis; D006580:Genetic Carrier Screening; D006801:Humans; D007223:Infant; D007437:Intrinsic Factor / Q000172:deficiency*; D014806:Vitamin B 12 Deficiency / Q000151:congenital
chemical_list: D007437:Intrinsic Factor
vernacular_title: Déficit congénital en facteur intrinsèque. A propos de 3 cas dans une fratrie.