title: Dosimetric calculations and measurements of gold plaque ophthalmic irradiators using iridium-192 and iodine-125 seeds.
abstract: The dosimetry of ophthalmic plaques designed to hold iridium-192 or iodine-125 seeds is investigated experimentally and by means of a computer model. A phantom for thermoluminescent dosimetry (TLD) which permits measurements to within 2 mm of the plaque surface is described. TLD data are compared with model calculations that take into account the active length of the seeds, anisotropy of dose distribution from single seeds, and scatter within the phantom. An isotropic point source calculational model is accurate for clinical calculations, particularly at depths greater than 5 mm. Relative central axis dose measurements for 125I in a gold plaque are also in agreement with the model. Comparisons of 192Ir, 125I and 60Co plaques are presented. The relative advantages of using these isotopes in eye plaques are discussed.
authors.affiliation: Department of Radiation Oncology, University of Southern California School of Medicine, Los Angeles.
authors.forename: G
authors.initials: G
authors.lastname: Luxton
authors.forename: M A
authors.initials: MA
authors.lastname: Astrahan
authors.forename: P E
authors.initials: PE
authors.lastname: Liggett
authors.forename: D L
authors.initials: DL
authors.lastname: Neblett
authors.forename: D M
authors.initials: DM
authors.lastname: Cohen
authors.forename: Z
authors.initials: Z
authors.lastname: Petrovich
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation*; D005134:Eye Neoplasms / Q000532:radiotherapy*; D006046:Gold; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D007496:Iridium Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D011880:Radiotherapy Planning, Computer-Assisted; D011881:Radiotherapy, Computer-Assisted
chemical_list: D007457:Iodine Radioisotopes; D007496:Iridium Radioisotopes; D006046:Gold