title: [Idiopathic thrombocytopenic purpura in children. Apropos of 98 cases].
abstract: The authors report a retrospective study of 98 cases of idiopathic thrombocytopenic purpura in children. The sex ratio was 1/1 and the mean age 5 years. A history of viral infection preceded the purpura in 45% of the cases. Sudden onset was observed in 81%. The platelet count was less than 20,000 mm3 in 78.5%. A follow-up was obtained in 79 patients: 76% had an acute disease. A spontaneous remission occurred in 88.6% of the cases, most of them in the first six months (49 cases/68), and in 10 cases/68 between 7 and 11 months after onset. Six patients presented one or two relapses prior to recovery. The illness became chronic in 11% of the patients despite prednisone therapy. Four patients were treated by splenectomy, in 3 cases with success. Two children died, one girl from cerebral haemorrhage and one boy from septicemia.
authors.affiliation: Service de pédiatrie, Hôpital d'Enfants, Jebbari, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Trabelsi
authors.forename: R
authors.initials: R
authors.lastname: Zeougha
authors.forename: K
authors.initials: K
authors.lastname: Dallagi
authors.forename: F
authors.initials: F
authors.lastname: Khaldi
authors.forename: B
authors.initials: B
authors.lastname: Bennaceur
mesh_terms: D000208:Acute Disease; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000188:drug therapy / Q000276:immunology / Q000503:physiopathology / Q000628:therapy; D012189:Retrospective Studies; D013156:Splenectomy; D013997:Time Factors; D014416:Tunisia
chemical_list: D011241:Prednisone
vernacular_title: Le purpura thrombocytopénique idiopathique de l'enfant. A propos de 98 cas.