[Increased cholinergic stimulating gastric secretion after truncal vagotomy in rats].
The reasons of the relapses after vagotomy are not clarified completely. The reactivity of the 3 postulated receptors in the parietal cell was investigated by means of a perfusion model in the rat in a control group and after truncus vagotomy 28 days before the experiment. Not any difference was shown between the control group or the vagotomy group after histamine and pentagastrin stimulation. A significant greater secretion (!) with negative insulin test was observed in the vagotomy group after carbachol stimulation.
Albrecht
R
R
Klinik und Poliklinik für Chirurgie der Medizinischen Akademie Erfurt.
Nowak
W
W
Blech
W
W
D000818:Animals; D002217:Carbachol / Q000494:pharmacology*; D005260:Female; D005750:Gastric Juice / Q000187:drug effects / Q000378:metabolism*; D010295:Parietal Cells, Gastric / Q000378:metabolism; D010418:Pentagastrin / Q000494:pharmacology; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D014629:Vagotomy, Proximal Gastric
D002217:Carbachol; D010418:Pentagastrin
Erhöhte cholinerg stimulierbare Magensekretion nach trunkulärer Vagotomie an der Ratte.