[Changes in various activation indices as a function of the value given by a stimulus in anhedonic and deprossogenic subjects].
The aim of this experiment was to investigate, in "normal" subjects, the relationship between personality characteristics (anhedonia and depressogenic attitudes) and various tonic and phasic activation indices (EEG power spectra, CNV (at Fz and Cz), heart rate and reaction time) recorded during auditory stimulations, and the influence of the affective value of stimuli on phasic activation indices. Eighteen subjects were divided into two opposite groups according to their scores on two self-rating questionnaires (the Chapman Physical Anhedonia Scale and the Beck-Weissman Dysfunctional Attitude Scale): the A group (anhedonic with depressogenic attitudes) and the H group (hedonic and non-depressogenic). The experiment was divided into three phases. The first and third phase utilised an identical classical CNV paradigm. During the second phase, two of the three neutral warning tones of the first phase were given, by conditioning, a positive or a negative value. The results showed that: 1) before conditioning, when all stimuli were neutral, all activation indices (tonic and phasic) were significantly higher in the A group than in the H group; 2) after conditioning, the two groups differed mainly by their cortical reactivity to the positively conditioned sound: the amplitude of the two CNV components increased in the H group whereas a tendency to a CNV decrease was seen in the A group; 3) all the between-group CNV differences were significant only at Fz. These results were discussed in terms of differences of optimal level of activation.
Pierson
A
A
Laboratory d'électrophysiologie, Hôpital de la Salpêtrière, Paris, France.
Ragot
R
R
Ripoche
A
A
Lesèvre
N
N
D000161:Acoustic Stimulation; D000328:Adult; D003213:Conditioning, Psychological / Q000502:physiology*; D003265:Contingent Negative Variation; D003863:Depression / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D011930:Reaction Time / Q000502:physiology
Modifications d'indices d'activation variés en fonction de la valence acquise par un stimulus chez des sujets anhédoniques et dépressogenes.