title: Acute acalculous cholecystitis--experimental and clinical observations.
abstract: Induction of acute acalculous cholecystitis was studied in dogs. Designed models included ligation of the cystic artery and/or duct separately or combined and injection of colonic flora into the gallbladder. Cholecystectomy was performed 72 h later. Histological studies of the gallbladders and bile cultures demonstrated various degrees of cholecystitis, the severest form occurring as a result of cystic artery ligation, whereas the mildest was produced by injection of bacteria. Secondary infection was a constant feature of our experimental models.
authors.affiliation: Department of Surgery C, Soroka Medical Center, Beer Sheva, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Shaked
authors.forename: A
authors.initials: A
authors.lastname: Ovnat
authors.forename: A
authors.initials: A
authors.lastname: Eyal
authors.forename: D
authors.initials: D
authors.lastname: Fraser
authors.forename: J
authors.initials: J
authors.lastname: Klain
authors.forename: J
authors.initials: J
authors.lastname: Peiser
authors.forename: I
authors.initials: I
authors.lastname: Charuzi
mesh_terms: D000208:Acute Disease; D000818:Animals; D002763:Cholecystectomy; D002764:Cholecystitis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D002767:Cholecystostomy; D003549:Cystic Duct; D004195:Disease Models, Animal; D004285:Dogs; D008026:Ligation