[Antipyrine test in petrochemical industry workers exposed to benzene].
Forty petrochemical industry workers occupationally exposed to benzene levels within TLVs (30 mg.m-3) had their hepatic microsomal enzyme function quantitatively assessed by the antipyrine test. The clearance (C1AP) and half life (P1/2) of antipyrine in the saliva were determined. The benzene-exposed workers exhibited increased C1AP and decreased P1/2, as compared to 20 control subjects. The occupational exposure to benzene at the concentrations exceeding 30 mg.m-3 seems to induce the microsomal enzyme function of the liver.
Paradowski
M
M
Zakładu Analityki Lekarskiej, Instytutu Diagnostyki WAM w Lodzi.
Roczek
E
E
Dworniak
D
D
D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D000983:Antipyrine; D001554:Benzene / Q000633:toxicity*; D001711:Biotransformation; D002617:Chemical Industry; D006801:Humans; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D008875:Middle Aged; D010578:Petroleum; D012463:Saliva / Q000378:metabolism
D000395:Air Pollutants, Occupational; D010578:Petroleum; D001554:Benzene; D000983:Antipyrine
Test antypirynowy u ludzi eksponowanych na benzen w przemyśle petrochemicznym.