title: Magnetic resonance imaging in pre-senile dementia of the Alzheimer-type, multi-infarct dementia and Korsakoff's syndrome.
abstract: Magnetic resonance imaging T1 values in Alzheimer's disease (ATD) were similar to age-matched controls although frontal T1 values tended to increase intraindividually with progression of the dementia. T1 values were raised, in both cortical grey and white matter, in Korsakoff's syndrome and multi-infarct dementia. T1 values appear of little value in studying the neuropathological changes in ATD in relationship to the neuropsychological deficits, but can assist in the differential diagnosis of pre-senile dementia.
authors.affiliation: MRC Brain Metabolism Unit, University of Edinburgh.
authors.forename: J E
authors.initials: JE
authors.lastname: Christie
authors.forename: D M
authors.initials: DM
authors.lastname: Kean
authors.forename: R H
authors.initials: RH
authors.lastname: Douglas
authors.forename: H M
authors.initials: HM
authors.lastname: Engleman
authors.forename: D
authors.initials: D
authors.lastname: St Clair
authors.forename: I M
authors.initials: IM
authors.lastname: Blackburn
mesh_terms: D000368:Aged; D000425:Alcohol Amnestic Disorder / Q000473:pathology* / Q000523:psychology; D000544:Alzheimer Disease / Q000473:pathology* / Q000523:psychology; D001284:Atrophy; D001921:Brain / Q000473:pathology; D003704:Dementia / Q000473:pathology* / Q000523:psychology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests