Blood lymphocytes in neuronal ceroid lipofuscinosis.
Ultrastructural examination of white blood cells of 8 patients with neuronal ceroid lipofuscinosis showed the characteristic cytosomes, i.e. curvilinear bodies, fingerprint profiles, osmiophilic bodies, as seen in nerve cells. The reliability of this simple technique in the diagnostic work-up of this progressive neurodegenerative disorder is emphasized.
Simonati
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Servizio di Neuropatologia, Università degli Studi di Verona.
Rizzuto
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D002648:Child; D002675:Child, Preschool; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009472:Neuronal Ceroid-Lipofuscinoses / Q000175:diagnosis / Q000276:immunology* / Q000473:pathology