N6-[2-(3,5-dimethoxyphenyl)-2-(2-methylphenyl)ethyl]adenosine and its uronamide derivatives. Novel adenosine agonists with both high affinity and high selectivity for the adenosine A2 receptor.
Bridges
A J
AJ
Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, Michigan 48105.
Bruns
R F
RF
Ortwine
D F
DF
Priebe
S R
SR
Szotek
D L
DL
Trivedi
B K
BK
D000241:Adenosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism; D019830:Adenosine-5'-(N-ethylcarboxamide); D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D051381:Rats; D011983:Receptors, Purinergic / Q000378:metabolism*; D013329:Structure-Activity Relationship
D011983:Receptors, Purinergic; C056426:CGS 24012; D019830:Adenosine-5'-(N-ethylcarboxamide); D000241:Adenosine