title: Lentinellic acid, a biologically active protoilludane derivative from Lentinellus species (Basidiomycetes).
abstract: A new antimicrobial and cytotoxic sesquiterpenoid, lentinellic acid, has been isolated from submerged cultures of Lentinellus ursinus and L. omphalodes. The structure of the antibiotic was elucidated by spectroscopic methods and a single crystal X-ray analysis. 1 may be formed biogenetically by condensation of a protoilludane aldehyde 4 with a malonate unit.
authors.affiliation: LB Biotechnologie der Universität, Kaiserslautern, Bundesrepublik Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Stärk
authors.forename: T
authors.initials: T
authors.lastname: Anke
authors.forename: U
authors.initials: U
authors.lastname: Mocek
authors.forename: W
authors.initials: W
authors.lastname: Steglich
authors.forename: A
authors.initials: A
authors.lastname: Kirfel
authors.forename: G
authors.initials: G
authors.lastname: Will
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification*; D001419:Bacteria / Q000187:drug effects; D001487:Basidiomycota / Q000254:growth & development*; D005285:Fermentation; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D012717:Sesquiterpenes / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000903:Antibiotics, Antineoplastic; D012717:Sesquiterpenes; C056500:lentinellic acid