title: Longitudinal study of plasma lipids and lipoprotein cholesterol in normal pregnancy and puerperium.
abstract: Plasma lipids and lipoprotein cholesterol distribution were measured in 60 normal pregnancies studied longitudinally at 12, 20, 28, and 36 weeks of gestation and 3 and 40 days postpartum. Total cholesterol, unesterified cholesterol, phospholipids, triglycerides and cholesterol in low- and very-low-density lipoproteins rose progressively during pregnancy. Maximal values were reached at 36 weeks for total cholesterol, unesterified cholesterol and low-density lipoprotein cholesterol and at partum for triglycerides, very-low-density lipoprotein cholesterol and phospholipids. High-density lipoprotein cholesterol was hardly affected by pregnancy. During the second half of pregnancy and postpartum period, high-density lipoprotein cholesterol was consistently and negatively correlated with triglycerides and very-low-density lipoprotein cholesterol. In each period studied total cholesterol showed very high positive correlation with low-density lipoprotein cholesterol but a weak correlation with high-density lipoprotein cholesterol.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Zaragoza, Spain.
authors.forename: D M
authors.initials: DM
authors.lastname: Jimenez
authors.forename: M
authors.initials: M
authors.lastname: Pocovi
authors.forename: J
authors.initials: J
authors.lastname: Ramon-Cajal
authors.forename: M A
authors.initials: MA
authors.lastname: Romero
authors.forename: H
authors.initials: H
authors.lastname: Martinez
authors.forename: F
authors.initials: F
authors.lastname: Grande
mesh_terms: D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008137:Longitudinal Studies; D049590:Postpartum Period / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D011257:Pregnancy Proteins / Q000378:metabolism; D013030:Spain
chemical_list: D008055:Lipids; D008074:Lipoproteins; D011257:Pregnancy Proteins; C030104:lipoprotein cholesterol; D002784:Cholesterol