Deep prepiriform cortex lesion and development of amygdala kindling.
The effects of a unilateral thermocoagulating lesion of the deep prepiriform cortex on the development of amygdala kindling were studied in adult rats. The lesion did not alter the local excitability of the ipsilateral amygdala. Furthermore, the number of stimulations required to produce generalized seizures did not significantly differ between lesioned and control animals. The results suggest that the deep prepiriform cortex may not be important in the development of amygdala kindling.
Ludvig
N
N
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York.
Moshé
S L
SL
D000679:Amygdala / Q000503:physiopathology*; D000818:Animals; D002540:Cerebral Cortex / Q000503:physiopathology*; D007696:Kindling, Neurologic; D008297:Male; D051381:Rats