Effect of blood bonding on bursting strength of laser-assisted microvascular anastomoses.
This experiment evaluated the influence of blood on the weld strength of laser-assisted microvascular anastomoses (LAMA). Rat femoral arteries were anastomosed end-to-end by either direct laser welding (group I) or by a blood-bonded technique (group II) whereby fresh blood was applied to the vessel edges before laser exposure. Bursting strength was measured at 0, 1, and 24 hours and at 3 and 7 days by infusing methylene blue into the vessel while pressure was monitored. The results showed significantly increased bursting strength in group II compared with group I at 0 hour and 7 days (P less than 0.05). There was a significant increase in bursting strength in group I from 0 hour to 1 hour (P less than 0.05). It is concluded that blood-bonding enhances the early bursting strength of LAMAs and may facilitate arterial wall healing.
Wang
S
S
Department of Cardiovascular Surgery, Maimonides Medical Center, Brooklyn, New York 11219.
Grubbs
P E
PE
Basu
S
S
Robertazzi
R R
RR
Thomsen
S
S
Rose
D M
DM
Jacobowitz
I J
IJ
Cunningham
J N
JN
D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001790:Blood Physiological Phenomena; D005263:Femoral Artery / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D053685:Laser Therapy; D008297:Male; D008866:Microsurgery; D051381:Rats; D011919:Rats, Inbred Strains; D013718:Tensile Strength; D014656:Vascular Surgical Procedures; D014945:Wound Healing