title: Presence of diguanosine tri, tetra-, and pentaphosphates in commercial samples of GTP and guanosine 5'-tetraphosphate.
abstract: Commercial samples of GTP and guanosine 5'-tetraphosphate were analyzed, with or without previous treatment with alkaline phosphatase, by high-pressure liquid chromatography on a Hypersil ODS column. They showed the presence of diguanosine 5',5"'-Pl,Pn-tri, tetra-, and pentaphosphates in varying amounts depending on the sample, but usually in proportions of around 0.3%.
authors.affiliation: Bioquímica y Biología Molecular y Genética, Facultad de Medicina, Universidad de Extremadura, Badajoz, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Buitrago
authors.forename: J
authors.initials: J
authors.lastname: Canales
authors.forename: A
authors.initials: A
authors.lastname: Sillero
mesh_terms: D000469:Alkaline Phosphatase; D015226:Dinucleoside Phosphates; D004340:Drug Contamination; D004345:Drug Industry / Q000592:standards; D006150:Guanine Nucleotides / Q000032:analysis*; D006159:Guanosine Tetraphosphate / Q000031:analogs & derivatives / Q000032:analysis*; D006160:Guanosine Triphosphate / Q000031:analogs & derivatives / Q000032:analysis* / Q000592:standards; D006868:Hydrolysis; D008099:Liver / Q000032:analysis; D009132:Muscles / Q000032:analysis
chemical_list: D015226:Dinucleoside Phosphates; D006150:Guanine Nucleotides; D006159:Guanosine Tetraphosphate; C015138:diguanosine tetraphosphate; C015139:diguanosine triphosphate; C056829:diguanosine pentaphosphate; D006160:Guanosine Triphosphate; D000469:Alkaline Phosphatase