title: [A case of leiomyosarcoma of the duodenum--histologic diagnostic criteria of borderline malignancy].
abstract: A case of a leiomyosarcoma of the duodenum is reported. A 52-year-old man with a duodenal submucosal tumor underwent a pancreatico-duodenectomy. Histologically, the resected tumor revealed moderate cellular atypism and moderate pleomorphism, but revealed no mitotic figures. The histological diagnosis was leiomyoma. Nine years after operation, the tumor showed a recurrence and metastasis in the liver. Thus, the patient underwent a lobectomy of the liver. The resected liver tumor showed similar histological features seen in the primary duodenal tumor but with high mitotic activity. Histologically, the patient was diagnosed as having a metastatic leiomyosarcoma. This history suggests that a smooth muscle tumor of potential malignancy, as seen in this case, should be followed continuously, even though mitoses may not be recognized.
authors.affiliation: Dept. of Pathology, Kure National Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Yamane
authors.forename: K
authors.initials: K
authors.lastname: Kirimoto
authors.forename: M
authors.initials: M
authors.lastname: Fujita
authors.forename: Y
authors.initials: Y
authors.lastname: Enomoto
authors.forename: T
authors.initials: T
authors.lastname: Toda
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Hada
authors.forename: K
authors.initials: K
authors.lastname: Fukuyama
authors.forename: K
authors.initials: K
authors.lastname: Hirata
authors.forename: T
authors.initials: T
authors.lastname: Oda
mesh_terms: D003937:Diagnosis, Differential; D004379:Duodenal Neoplasms / Q000473:pathology* / Q000601:surgery; D004386:Duodenum / Q000601:surgery; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000601:surgery