title: [Transitory prolongation of QT time in severely ill premature and newborn infants].
abstract: Over 24 months in a Neonatal Intensive Care Unit 118 electrocardiograms were recorded in the first three days of life. 12 preterm and term newborns had a corrected QT-time-prolongation over 0.44 s. Measurement of the ionized calcium level in these children revealed hypocalcemia in only four as a reason for QT-time-prolongation. One child had hypokalemia, one child suffered from accidental Bupivacain injection. In the other six children no known reasons for QT-time-prolongation could be found. The QT-time-prolongation persisted for a maximum of three months, no inherited QT-syndrome existed. We discuss a correlation of these transitory QT-time-prolongation with asphyxia which preexisted in all six children. Influences on catecholamine receptors of myocardium or changes in central sympathicotonus may be assumed.
authors.affiliation: Klinik für Kinderheilkunde der Medizinischen Universität zu Lübeck.
authors.forename: J C
authors.initials: JC
authors.lastname: Möller
authors.forename: F K
authors.initials: FK
authors.lastname: Tegtmeyer
authors.forename: T
authors.initials: T
authors.lastname: Rose
mesh_terms: D001145:Arrhythmias, Cardiac / Q000503:physiopathology*; D001238:Asphyxia Neonatorum / Q000503:physiopathology; D002118:Calcium / Q000097:blood; D004562:Electrocardiography; D006329:Heart Conduction System / Q000503:physiopathology; D006801:Humans; D006996:Hypocalcemia / Q000503:physiopathology; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000503:physiopathology*; D008133:Long QT Syndrome / Q000503:physiopathology*; D012307:Risk Factors; D013610:Tachycardia / Q000503:physiopathology
chemical_list: D002118:Calcium
vernacular_title: Passagere QT-Zeit-Verlängerung bei schwerkranken Früh- und Neugeborenen.