title: Distribution of Campylobacter pylori in the human stomach obtained at postmortem.
abstract: The distribution of Campylobacter pylori, its prevalence, and its relationship to gastritis and urease activity have been studied in 54 postmortem stomachs. Infection was confirmed by finding C. pylori in a Gram-stained smear of gastric mucus harvested from the entire stomach. Eight tissue specimens were obtained from predetermined sites from each stomach and examined for histologic gastritis and urease activity. Thirty-seven per cent of stomachs were infected, and of these 80% had widespread histologic gastritis. The detection of urease activity provided information on the distribution of the organism and had a high correlation with histologic gastritis. The organism is capable of infecting any area of the stomach. Infection is common and is more prevalent in Polynesian subjects (60%) than in Caucasians (19%).
authors.affiliation: Dept. of Microbiology, Auckland Hospital, New Zealand.
authors.forename: A
authors.initials: A
authors.lastname: Morris
authors.forename: K
authors.initials: K
authors.lastname: Maher
authors.forename: L
authors.initials: L
authors.lastname: Thomsen
authors.forename: M
authors.initials: M
authors.lastname: Miller
authors.forename: G
authors.initials: G
authors.lastname: Nicholson
authors.forename: C
authors.initials: C
authors.lastname: Tasman-Jones
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001344:Autopsy; D002167:Campylobacter / Q000302:isolation & purification*; D002169:Campylobacter Infections / Q000473:pathology; D002648:Child; D005260:Female; D005756:Gastritis / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013270:Stomach / Q000382:microbiology* / Q000473:pathology; D014510:Urease / Q000378:metabolism
chemical_list: D014510:Urease