title: Growth related increase in an intervertebral disc space in rats.
abstract: Methods have been developed that permit repetitive radiographic measurement of the lumbar L4-5 intervertebral disc space area in the laboratory rat. In using this approach, the coefficient of variation in repetitive determinations was 7.6 +/- 0.7%. Normal rats have been shown to manifest statistically significant increase in disc space area size between 2.5 and 5 months of age.
authors.affiliation: Veterans Administration Medical Center, Department of Radiology and Animal Research Facility, San Diego, CA 92161.
authors.forename: J H
authors.initials: JH
authors.lastname: Neufeld
authors.forename: D
authors.initials: D
authors.lastname: Sartoris
authors.forename: L
authors.initials: L
authors.lastname: Margolin
authors.forename: D
authors.initials: D
authors.lastname: Resnick
mesh_terms: D000818:Animals; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000254:growth & development*; D008159:Lumbar Vertebrae; D008297:Male; D011859:Radiography; D051381:Rats; D011919:Rats, Inbred Strains / Q000033:anatomy & histology* / Q000254:growth & development; D012044:Regression Analysis; D012984:Software