title: Resolution of stereoisomers of dipeptides by gas chromatography on Chirasil-Val.
abstract: Several dipeptides have been separated into stereoisomers (enantiomers, diastereomers, sequential isomers) by gas chromatography on Chirasil-Val. Sufficiently volatile N-trifluoroacetyl dipeptide methyl esters were formed at ambient temperature, thus avoiding racemization (or epimerization, respectively, and cleavage of the peptide bond. This method is suitable for ascertaining the stereoisomeric composition of dipeptides in biological samples.
authors.affiliation: Institut für Organische Chemie der Universität, Tübingen, F.R.G.
authors.forename: B
authors.initials: B
authors.lastname: Koppenhoefer
authors.forename: H
authors.initials: H
authors.lastname: Allmendinger
authors.forename: L P
authors.initials: LP
authors.lastname: Chang
authors.forename: L B
authors.initials: LB
authors.lastname: Cheng
mesh_terms: D002849:Chromatography, Gas; D004151:Dipeptides / Q000032:analysis*; D013237:Stereoisomerism
chemical_list: D004151:Dipeptides