[Effect of penicillin on the discrimination function of the auditory cortex neurons in the cat].
Responses and receptive fields of neurons in auditory cortex (AI) were studied in acute nembutal-anaesthetized cats before and during ionophoretic application of penicillin. Frequency and duration of impulse responses to tone bursts were increased during application in the majority (83%) of neurons. Increase of receptive fields and decline of frequency selectivity were found in 80% of neurons. The data obtained are regarded as proofs of decisive role of GABA-ergic inhibition in formation of functional receptive fields of auditory cortical neurons.
Volkov
I O
IO
Taranov
I D
ID
Galaziuk
A V
AV
D000818:Animals; D001303:Auditory Cortex / Q000187:drug effects* / Q000502:physiology; D002415:Cats; D004192:Discrimination, Psychological / Q000187:drug effects* / Q000502:physiology; D007478:Iontophoresis; D009433:Neural Inhibition / Q000187:drug effects; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D010406:Penicillins / Q000494:pharmacology*
D010406:Penicillins
Vliianie penitsillina na diskriminatsionnuiu funktsiiu neĭronov slukhovoĭ kory koshki.