Comparison of phospholipid synthesis in rat salivary glands: properties of 1-acylglycerophosphorylcholine and 1-acylglycerophosphate acyltransferase systems in microsomes.
1. 1-Acyl-sn-glycerol-3-phosphorylcholine and 1-acyl-sn-glycerol-3-phosphate acyltransferase activities were characterized in rat salivary gland microsomes. 2. The acyl-CoA selectivities between these two kinds of lysophospholipid acyltransferase activities were very different. 3. When the three major glands were compared (parotid, submandibular, sublingual), they showed their own particular acyltransferase activity, but they had very similar in acyl-CoA selectivity. 4. Those observations were also compared in rat liver microsomes.
Kameyama
Y
Y
Department of Oral Biochemistry, Asahi University School of Dentistry, Gifu, Japan.
Yashiro
K
K
Mizuno
M
M
Okada
A
A
Takahashi
K
K
Hayashi
S
S
Yokota
Y
Y
D051103:1-Acylglycerol-3-Phosphate O-Acyltransferase; D000214:Acyl Coenzyme A / Q000378:metabolism; D000217:Acyltransferases / Q000378:metabolism*; D000818:Animals; D007700:Kinetics; D008297:Male; D008861:Microsomes / Q000201:enzymology*; D008862:Microsomes, Liver / Q000201:enzymology*; D009928:Organ Specificity; D010713:Phosphatidylcholines / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains; D012469:Salivary Glands / Q000201:enzymology*; D013379:Substrate Specificity
D000214:Acyl Coenzyme A; D010713:Phosphatidylcholines; D000217:Acyltransferases; D051103:1-Acylglycerol-3-Phosphate O-Acyltransferase