Early relapse of acute inflammatory polyradiculoneuropathy after successful treatment with plasma exchange.
Symptoms reappeared within 2-4 weeks in 6 of 23 patients with acute Guillain-Barré syndrome who had demonstrated significant clinical improvement following plasma exchange therapy; all however improved to full recovery after a second series of plasma exchanges. The procedure appears to be associated with increased risk of early relapse. Our observations suggest that a relationship may exist between rapid removal of large amounts of plasma and the possibility of relapse.
Osterman
P O
PO
Department of Neurology, University Hospital, Uppsala, Sweden.
Fagius
J
J
Säfwenberg
J
J
Wikström
B
B
D000208:Acute Disease; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010951:Plasma Exchange; D011129:Polyradiculoneuropathy / Q000628:therapy*; D012008:Recurrence; D013997:Time Factors