[Prevention of the formation of alcoholic motivation in rats using zinc sulfate].
The experiments carried out on albino male rats have shown a decreased zinc content in the brain of active animals selected under conditions of forced swimming test, as compared to passive animals. 10-day intraperitoneal injection of biotic zinc sulfate dose (50 micrograms/kg) resulted in the prevention of alcohol motivation in active animals. There was no such effect in passive animals. The differences between basic mechanisms of alcohol motivation in different groups of animals are suggested.
Skal'nyĭ
A V
AV
Kampov-Polevoĭ
A B
AB
D000437:Alcoholism / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology*; D000818:Animals; D001921:Brain / Q000378:metabolism; D008297:Male; D009042:Motivation / Q000187:drug effects* / Q000502:physiology; D005082:Physical Exertion; D051381:Rats; D013431:Sulfates / Q000627:therapeutic use*; D015032:Zinc / Q000378:metabolism / Q000627:therapeutic use*; D019287:Zinc Sulfate
D013431:Sulfates; D019287:Zinc Sulfate; D015032:Zinc
Preduprezhdenie vozniknoveniia alkogol'noĭ motivatsii u krys sulfatom tsinka.