Successful long term oral zinc in florid Wilson's disease: a case report.
We describe the clinical course of a patient with florid, predominantly neurological, Wilson's disease who developed serious toxic effects of d-penicillamine therapy but responded well to long term oral zinc sulphate. A congenital portosystemic shunt has decompressed the portal bed adequately to prevent the development of varices. We also documented the return to normal of a grossly abnormal pancreolauryl test after withdrawal of zinc.
Kaur
U
U
Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Bambery
P
P
Bhushnurmath
S R
SR
Deodhar
S D
SD
Dilawari
J B
JB
D000284:Administration, Oral; D000293:Adolescent; D003300:Copper / Q000652:urine; D006527:Hepatolenticular Degeneration / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007194:India; D008297:Male; D010396:Penicillamine / Q000009:adverse effects* / Q000627:therapeutic use; D013431:Sulfates / Q000627:therapeutic use*; D015032:Zinc / Q000627:therapeutic use*; D019287:Zinc Sulfate
D013431:Sulfates; D019287:Zinc Sulfate; D003300:Copper; D010396:Penicillamine; D015032:Zinc