Effect of ABO incompatibility on the fate in vivo of 111Indium granulocytes.
The effect of ABO incompatibility on the in vivo fate of 111Indium granulocytes was determined. The intravascular recovery and survival (t1/2) and extravascular migration into a skin window of normal-donor granulocytes did not differ in 15 subjects from the values obtained in four controls who received ABO-compatible granulocytes. Nor was the correlation between the ABO antibody titers and the in vivo measurements strongly positive. It is concluded that ABO incompatibility did not alter the in vivo fate of granulocytes.
McCullough
J
J
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis.
Clay
M
M
Loken
M
M
Hurd
D
D
D000017:ABO Blood-Group System; D001787:Blood Group Incompatibility / Q000503:physiopathology*; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D007204:Indium / Q000378:metabolism; D007205:Indium Radioisotopes; D007700:Kinetics
D000017:ABO Blood-Group System; D007205:Indium Radioisotopes; D007204:Indium