Cross-reactivity studies on bacteria believed to be associated with inflammatory bowel disease (IBD), ankylosing spondylitis (AS) and reactive arthritis (ReA).
Six bacteria believed to be associated with IBD and/or AS and ReA were investigated for antigenic cross-reactivity using an ELISA. Considerable degrees of cross-reactivity were detected and it is suggested that if bacterial antigens are involved aetiologically in the diseases, no specific bacterium is concerned.
Pease
P E
PE
Chahal
H
H
Tallack
J E
JE
Lane
M R
MR
Allan
R N
RN
D000942:Antigens, Bacterial / Q000032:analysis; D001172:Arthritis, Rheumatoid / Q000382:microbiology*; D003424:Crohn Disease / Q000382:microbiology*; D003429:Cross Reactions; D004755:Enterobacteriaceae / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D000091402:Prohibitins; D013167:Spondylitis, Ankylosing / Q000382:microbiology*
D000942:Antigens, Bacterial; C000717331:PHB2 protein, human; D000091402:Prohibitins