Comparison of glucose/electrolyte and glucose/glycine/electrolyte oral rehydration solutions in hospitalized children with diarrhea in Costa Rica.
The experience of Nalin et al. and Patra et al. with a "super oral rehydration solution (ORS)" containing glucose plus glycine to enhance the intestinal absorption of sodium and water prompted us to investigate a similar ORS containing the standard World Health Organization (WHO/ORS) plus either 55 or 110 mmol/L glycine in infants and small children with noncholera diarrhea. We did not find a statistically significant difference between the glycine-fortified ORS and the standard WHO/ORS with respect to the clinical outcome and composition of serum electrolytes.
Pizarro
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Pizarro at Servicio de Emergencias Médicas, National Children's Hospital, San José, Costa Rica.
Levine
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MM
Posada
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G
Sandi
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L
D001639:Bicarbonates / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002675:Child, Preschool; D003364:Costa Rica; D003967:Diarrhea / Q000378:metabolism / Q000628:therapy*; D005440:Fluid Therapy / Q000009:adverse effects / Q000379:methods*; D005947:Glucose / Q000008:administration & dosage*; D005998:Glycine / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008297:Male; D011188:Potassium / Q000008:administration & dosage* / Q000378:metabolism; D011897:Random Allocation; D012964:Sodium / Q000008:administration & dosage* / Q000378:metabolism
D001639:Bicarbonates; D001786:Blood Glucose; D012964:Sodium; D005947:Glucose; D011188:Potassium; D005998:Glycine