[A case of leiomyosarcoma of the duodenum--histologic diagnostic criteria of borderline malignancy].
A case of a leiomyosarcoma of the duodenum is reported. A 52-year-old man with a duodenal submucosal tumor underwent a pancreatico-duodenectomy. Histologically, the resected tumor revealed moderate cellular atypism and moderate pleomorphism, but revealed no mitotic figures. The histological diagnosis was leiomyoma. Nine years after operation, the tumor showed a recurrence and metastasis in the liver. Thus, the patient underwent a lobectomy of the liver. The resected liver tumor showed similar histological features seen in the primary duodenal tumor but with high mitotic activity. Histologically, the patient was diagnosed as having a metastatic leiomyosarcoma. This history suggests that a smooth muscle tumor of potential malignancy, as seen in this case, should be followed continuously, even though mitoses may not be recognized.
Yamane
T
T
Dept. of Pathology, Kure National Hospital.
Kirimoto
K
K
Fujita
M
M
Enomoto
Y
Y
Toda
T
T
Kobayashi
S
S
Hada
Y
Y
Fukuyama
K
K
Hirata
K
K
Oda
T
T
D003937:Diagnosis, Differential; D004379:Duodenal Neoplasms / Q000473:pathology* / Q000601:surgery; D004386:Duodenum / Q000601:surgery; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000601:surgery