Differential effects of endolaryngeal trauma upon the growth of the subglottis.
In young rabbits (4-week-old) the growth of the subglottis was studied after an endolaryngeal soft tissue trauma. The injury induced the formation of a subglottic stenosis. In contrast to earlier observations on endolaryngeal trauma extending into the cricoid cartilage, the cricoid developed normally to the adult size and shape at 24 weeks. Similar to the earlier findings, the subepithelial layer showed considerable thickening as the result of formation of scar tissue, ectopic cartilage and fatty tissue with interruption of the elastic tunica (= conus elasticus). It was concluded that after endolaryngeal trauma in rabbits two types of subglottic stenosis can develop, determined by the depth of the injury.
Adriaansen
F C
FC
Department of Otorhinolaryngology, Erasmus University Rotterdam, The Netherlands.
Verwoerd-Verhoef
H L
HL
van der Heul
R O
RO
Verwoerd
C D
CD
D000818:Animals; D002921:Cicatrix / Q000473:pathology; D003413:Cricoid Cartilage / Q000254:growth & development* / Q000473:pathology; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D005931:Glottis; D007817:Laryngeal Cartilages / Q000254:growth & development*; D007829:Laryngostenosis / Q000473:pathology / Q000503:physiopathology*; D007830:Larynx / Q000254:growth & development* / Q000473:pathology; D011817:Rabbits