Occult thyroid dysfunction in patients with refractory depression.
Assessment of metabolic rate was useful in evaluating refractory depression in six of 15 women. Five of the six had normal levels of T3 and T4; however, each had an elevated thyrotropin-stimulating hormone level or a low metabolic rate. The depressions responded to medication with thyroid hormone.
Gewirtz
G R
GR
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY.
Malaspina
D
D
Hatterer
J A
JA
Feureisen
S
S
Klein
D
D
Gorman
J M
JM
D000328:Adult; D001481:Basal Metabolism; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications; D008875:Middle Aged; D013961:Thyroid Gland / Q000503:physiopathology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use; D014284:Triiodothyronine / Q000097:blood
D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine