Laser desorption/Fourier transform mass spectrometry of steroids.
Mass spectra of six representative underivatized steroids and three parent hydrocarbons were obtained using laser desorption/Fourier transform (LD/FT) mass spectrometry. The carbonyl steroids, with the exception of aldosterone, yielded abundant [M + H]+ ions. For cholesterol, a major fragment ion was that corresponding to dehydration. The hydrocarbons produced [M + H]+, M+ and [M - H]+ ions, in addition to expected alkyl cleavage ions including those resulting from methyl loss. The LD/FT mass spectra of all were qualitatively similar to electron ionization spectra, but showed somewhat less fragmentation.
Fung
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Department of Chemistry, University of California, Riverside 92521.
Wilkins
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D005583:Fourier Analysis; D007834:Lasers; D013058:Mass Spectrometry; D013256:Steroids / Q000032:analysis*
D013256:Steroids