title: Effect of blood bonding on bursting strength of laser-assisted microvascular anastomoses.
abstract: This experiment evaluated the influence of blood on the weld strength of laser-assisted microvascular anastomoses (LAMA). Rat femoral arteries were anastomosed end-to-end by either direct laser welding (group I) or by a blood-bonded technique (group II) whereby fresh blood was applied to the vessel edges before laser exposure. Bursting strength was measured at 0, 1, and 24 hours and at 3 and 7 days by infusing methylene blue into the vessel while pressure was monitored. The results showed significantly increased bursting strength in group II compared with group I at 0 hour and 7 days (P less than 0.05). There was a significant increase in bursting strength in group I from 0 hour to 1 hour (P less than 0.05). It is concluded that blood-bonding enhances the early bursting strength of LAMAs and may facilitate arterial wall healing.
authors.affiliation: Department of Cardiovascular Surgery, Maimonides Medical Center, Brooklyn, New York 11219.
authors.forename: S
authors.initials: S
authors.lastname: Wang
authors.forename: P E
authors.initials: PE
authors.lastname: Grubbs
authors.forename: S
authors.initials: S
authors.lastname: Basu
authors.forename: R R
authors.initials: RR
authors.lastname: Robertazzi
authors.forename: S
authors.initials: S
authors.lastname: Thomsen
authors.forename: D M
authors.initials: DM
authors.lastname: Rose
authors.forename: I J
authors.initials: IJ
authors.lastname: Jacobowitz
authors.forename: J N
authors.initials: JN
authors.lastname: Cunningham
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001790:Blood Physiological Phenomena; D005263:Femoral Artery / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D053685:Laser Therapy; D008297:Male; D008866:Microsurgery; D051381:Rats; D011919:Rats, Inbred Strains; D013718:Tensile Strength; D014656:Vascular Surgical Procedures; D014945:Wound Healing