title: [Doxycycline esophagitis and esophageal ulcer].
abstract: Four cases of acute doxycycline injury of the esophageal mucosa--acute catarrhal doxycycline esophagitis and acute doxycycline ulcer are presented. The pathogenesis, clinical course, endoscopic pattern, prophylaxis and treatment of these complications of doxycycline treatment are discussed in detail. The gastroesophageal and duodenogastric reflux, which are most often the result of functional failure of the lower esophageal sphincter, are pointed out as the basic pathogenetic mechanism of the esophageal mucosa injury in oral doxycycline treatment.
authors.forename: V
authors.initials: V
authors.lastname: Kolarski
authors.forename: K
authors.initials: K
authors.lastname: Petrova-Shopova
authors.forename: S
authors.initials: S
authors.lastname: Nikolov
authors.forename: E
authors.initials: E
authors.lastname: Vasileva
authors.forename: D
authors.initials: D
authors.lastname: Petrova
mesh_terms: D000208:Acute Disease; D000284:Administration, Oral; D000328:Adult; D002214:Capsules; D004318:Doxycycline / Q000009:adverse effects*; D004935:Esophageal Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D004941:Esophagitis / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D013997:Time Factors; D014456:Ulcer / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology
chemical_list: D002214:Capsules; D004318:Doxycycline
vernacular_title: Doksitsiklinov ezofagit i ezofagealna iazva.