title: Effect of sleep on middle latency response (MLR) in infants.
abstract: Auditory middle latency responses (MLR), with two click-rates (1.3 Hz, 8.9 Hz) and simultaneous polygraphic recording with EEG, EOG, EMG, ECG and respiratory rhythm have been recorded in 16, 6 or 7 week old infants to study the effect of sleep on the amplitudes of MLR. For both click-rates, response amplitude depended upon waking and sleep states, the Na-Pa complex being always greater during waking states. It is of very low amplitude during quiet and active sleep but significantly lower in quiet sleep. In some infants it disappears entirely in quiet sleep. MLRs have been said to be hard to reproduce in infants. Our results would suggest that this is due to a strong alertness effect on MLRs in infants.
authors.affiliation: Université Claude Bernard Lyon 1, Laboratoire de Physiologie Sensorielle, Faculté de Médecine Lyon-Sud, Oullins, France.
authors.forename: L
authors.initials: L
authors.lastname: Collet
authors.forename: R
authors.initials: R
authors.lastname: Duclaux
authors.forename: M J
authors.initials: MJ
authors.lastname: Challamel
authors.forename: M
authors.initials: M
authors.lastname: Revol
mesh_terms: D000367:Age Factors; D004569:Electroencephalography; D004576:Electromyography; D004585:Electrooculography; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011930:Reaction Time; D012890:Sleep / Q000502:physiology*; D014851:Wakefulness