Species differences in the distribution of infracuticular F-actin in outer hair cells of the cochlea.
The distribution of filamentous actin (F-actin) in outer hair cells has been examined in several mammalian species using tetramethylrhodamine phalloidin, a specific marker for F-actin. The stereocilia and cuticular plates of the OHC in all species examined (pigmented guinea pig, hooded rat, chinchilla and squirrel monkey) contained F-actin; however, an infracuticular network of F-actin was present in OHC of the apical turns of the guinea pig cochlea but could not be identified in any other species examined.
Carlisle
L
L
Institute of Laryngology and Otology, Royal National Throat, Nose and Ear Hospital, London, U.K.
Zajic
G
G
Altschuler
R A
RA
Schacht
J
J
Thorne
P R
PR
D000199:Actins / Q000032:analysis*; D000818:Animals; D002682:Chinchilla; D005456:Fluorescent Dyes; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000032:analysis*; D010590:Phalloidine / Q000031:analogs & derivatives; D051381:Rats; D012235:Rhodamines; D012453:Saimiri; D013045:Species Specificity
D000199:Actins; D005456:Fluorescent Dyes; D012235:Rhodamines; D010590:Phalloidine; C041085:tetramethylrhodaminylphalloidine