Inferior and superior vena caval blood flows during cross-clamping of the thoracic aorta in pigs.
Changes in blood flow through the inferior and superior venae cavae during cross-clamping of the thoracic aorta just above the diaphragm were studied in 28 miniature pigs anesthetized with enflurane titrated to maintain systemic arterial blood pressure close to normal values. Surgical preparation included sternotomy with subsequent placement of a noncannulating electromagnetic probe around the ascending aorta and a cannulating electromagnetic probe in the transected inferior vena cava. Superior vena caval flow was calculated as the difference between aortic flow and inferior vena caval flow. Clamping of the thoracic aorta alone (n = 10) was accompanied by severe arterial hypertension, a dramatic decrease in inferior vena caval flow, and an increase in superior vena caval flow, which resulted in a moderate increase in aortic flow. Simultaneous clamping of the thoracic aorta and inferior vena cava (n = 13) was accompanied by no significant change in arterial pressure or superior vena caval flow. The oxygen content in mixed venous blood significantly (p less than 0.05) increased from 9.5 +/- 1.1 to 13.4 +/- 1.8 ml.dl-1 in animals undergoing clamping of the thoracic aorta only, but did not change significantly in animals subjected to simultaneous clamping of the aorta and inferior vena cava. The study demonstrates a substantial increase in superior vena caval flow during cross-clamping of the thoracic aorta. Further studies elucidating the mechanism of the observed changes are required.
Gelman
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S
Department of Anesthesiology, University of Alabama, Birmingham 35294.
Rabbani
S
S
Bradley
E L
EL
D000818:Animals; D001013:Aorta, Thoracic / Q000502:physiology*; D002302:Cardiac Output; D003250:Constriction; D006439:Hemodynamics; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption; D012039:Regional Blood Flow; D013552:Swine; D013556:Swine, Miniature; D014684:Venae Cavae / Q000502:physiology*
D010100:Oxygen