Hb J-Cordoba [alpha 2A beta 2(95)(FG2)Lys----Met]. A new Hb variant found in Argentina.
Hb J-Cordoba [alpha 2A beta 2(95)(FG2)Lys----Met], is one of the few hemoglobin variants discovered in Argentina. The structure and functional abnormalities are described. Hb J-Cordoba exhibits a slightly increased oxygen affinity, low cooperativity, and normal interaction with heterotropic cofactors.
Bardakdjian
J
J
INSERM U.91, UA CNRS 607, Hp Henri Mondor, Créteil, France.
Kister
J
J
Rhoda
M D
MD
Marden
M
M
Arous
N
N
De Leon
J
J
North
M L
ML
Lacombe
C
C
Blouquit
Y
Y
Castracane
C
C
D000596:Amino Acids / Q000032:analysis*; D001118:Argentina; D001797:Blood Protein Electrophoresis; D005260:Female; D006448:Hemoglobin J / Q000032:analysis*; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D007223:Infant; D010100:Oxygen / Q000097:blood; D012995:Solubility
D000596:Amino Acids; D006455:Hemoglobins, Abnormal; C056328:hemoglobin J Cordoba; D006448:Hemoglobin J; D010100:Oxygen