title: Factors related to the initiation of cell migration along the inner surface of the blastocoelic wall during amphibian gastrulation.
abstract: Changes in the quantity of extracellular matrix on the inner surface of the blastocoelic wall (BW) and the adhesiveness of cells to fibronectin were examined in relation to the timing of initiation of cell migration along the BW during gastrulation of the newt, Cynops pyrrhogaster. Extracellular matrix fibrils were already abundantly present all over the inner surface of the BW prior to the beginning of cell migration. On the other hand, the adhesiveness of cells to fibronectin rapidly increased in the cells of the dorsal region at the same time as the cell migration initiated along the BW.
authors.affiliation: Department of Anatomy, Saitama Medical School, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Komazaki
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000166:cytology; D002448:Cell Adhesion; D002454:Cell Differentiation; D002465:Cell Movement; D002473:Cell Wall / Q000648:ultrastructure; D005109:Extracellular Matrix / Q000648:ultrastructure*; D005353:Fibronectins / Q000378:metabolism / Q000494:pharmacology; D005775:Gastrula / Q000166:cytology*; D008855:Microscopy, Electron, Scanning; D012455:Salamandridae / Q000196:embryology*
chemical_list: D005353:Fibronectins