title: Glucagon control of glycogenolysis in catfish tissues.
abstract: 1. In catfish (Ictalurus melas) after glucagon treatment blood glucose increased until 150 min, then it gradually decreased towards control values at the 5th hr. 2. In glucagon treated fish, liver glycogen levels were significantly lower then in controls 30 min after hormone administration; thereafter, liver glycogen levels returned rapidly to initial values. Glucagon did not induce any significant effect on the glycogen content in white and red muscles. 3. In liver slices, the addition of glucagon to the incubation medium significantly enhanced the glycogen phosphorylase activity and decreased the level of glycogen. Both phosphorylase activity and glycogen content of white and red muscle slices were practically unaffected by glucagon.
authors.affiliation: Institute of General Physiology, University of Ferrara, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Ottolenghi
authors.forename: A C
authors.initials: AC
authors.lastname: Puviani
authors.forename: A
authors.initials: A
authors.lastname: Baruffaldi
authors.forename: M E
authors.initials: ME
authors.lastname: Gavioli
authors.forename: L
authors.initials: L
authors.lastname: Brighenti
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002397:Catfishes / Q000378:metabolism*; D005934:Glucagon / Q000494:pharmacology*; D006003:Glycogen / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000187:drug effects; D008112:Liver Glycogen / Q000378:metabolism; D009132:Muscles / Q000187:drug effects / Q000378:metabolism; D009928:Organ Specificity; D006005:Phosphorylases / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D008112:Liver Glycogen; D006003:Glycogen; D005934:Glucagon; D006005:Phosphorylases