Applications of biotechnology in parasitic diseases in Malaysia.
Biotechnological tools are being used in malaria, filariasis and dengue research. The main emphasis has been on the production of reagents for immunodiagnosis and research. In this respect monoclonal antibodies (McAbs) against various species and stages of the above pathogens have been produced. It is hoped that these McAbs will be useful not only in immunodiagnosis but also for seroepidemiological applications. A DNA probe against Brugia malayi has been tested in Malaysia and was found to be sensitive and specific.
Mak
J W
JW
Institute for Medical Research, Kuala Lumpur, Malaysia.
Yong
H S
HS
Lim
P K
PK
Tan
M A
MA
D000818:Animals; D000911:Antibodies, Monoclonal; D001709:Biotechnology; D002009:Brugia / Q000235:genetics; D004274:DNA, Recombinant; D003715:Dengue / Q000175:diagnosis; D004605:Elephantiasis, Filarial / Q000175:diagnosis; D005368:Filariasis / Q000175:diagnosis; D006801:Humans; D008288:Malaria / Q000175:diagnosis; D008296:Malaysia; D010272:Parasitic Diseases / Q000175:diagnosis*
D000911:Antibodies, Monoclonal; D004274:DNA, Recombinant