Changes in contralateral synaptic acetylcholinesterase following motor nerve section in rats.
We report here that denervation of rat extensor digitorum longus, soleus and diaphragm muscle results in an increase of a subset of asymmetric acetylcholinesterase (class II A-forms) in the contralateral muscle, within a few days. This observation is interesting because it suggests a specific regulation of one asymmetric enzyme fraction, which is solubilized only in the presence of chelating agents and is thought to reside in the basal lamina.
Fadić
R
R
Department of Cell Biology, Catholic University of Chile, Santiago.
Soza
M A
MA
Inestrosa
N C
NC
D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D003714:Denervation; D007839:Functional Laterality / Q000502:physiology*; D008297:Male; D009046:Motor Neurons / Q000201:enzymology*; D009132:Muscles / Q000294:innervation*; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000201:enzymology*
D000110:Acetylcholinesterase