title: [Influence of isoptin on the anticoagulant effect of the sodium and calcium salts of heparin].
abstract: It was found that in buffer medium isoptin at concentrations of 0.025-0.0015 mg/ml failed to interact with heparin calcium. In experiments on rabbits isoptin (0.05-0.1 mg/kg) was shown to exert no effect on the time of whole blood coagulation, the time of recalcification and thrombin time and to produce no changes in the anticoagulant effect of heparin calcium but to increase the effect of heparin sodium.
authors.forename: E A
authors.initials: EA
authors.lastname: Ushkalova
authors.forename: V F
authors.initials: VF
authors.lastname: Kremneva
authors.forename: N V
authors.initials: NV
authors.lastname: Shcheglova
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D006493:Heparin / Q000494:pharmacology*; D066298:In Vitro Techniques; D011817:Rabbits; D013997:Time Factors; D014700:Verapamil / Q000494:pharmacology*
chemical_list: C006871:calcium heparin; D006493:Heparin; D014700:Verapamil
vernacular_title: Vliianie izoptina na antikoaguliantnyĭ éffekt natrievoĭ i kal'tsievoĭ soleĭ geparina.