[Evaluation of genetic consequences of 238Pu incorporation into mammals].
The genetic effects of gonadal burdens of 238Pu after single injection were studied in male mice. The activity of plutonium was 7 to 1850 Bk/g. The average doses of accumulated alpha-particles in testis varied from 2 to 96 Gy.10(-2), the dose rate being 0.004 to 1 Gy.10(-2) per day. The genetic end points are: the dominant lethal mutation rate; the frequency of reciprocal translocations; the recessive lethal mutation rate and frequency of abnormal sperm head morphology. For all tests used, no linear dependence of the effect on the alpha-dose was observed. The RBE value of alpha-irradiation was 10-20 relative to chronic gamma-irradiation.
Pomerantseva
M D
MD
Ramaĭia
L K
LK
Shevchenko
V A
VA
Vilkina
G A
GA
Liaginskaia
A M
AM
D000512:Alpha Particles; D000818:Animals; D001822:Body Burden; D005260:Female; D005720:Gamma Rays; D005804:Genes, Lethal / Q000528:radiation effects; D008297:Male; D051379:Mice; D009154:Mutation; D011005:Plutonium / Q000633:toxicity*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000235:genetics; D012062:Relative Biological Effectiveness
D011005:Plutonium
Otsenka geneticheskikh posledstviĭ postupleniia 238Pu v organizm mlekopitaiushchikh.