title: Melatonin in the lacrimal gland: first demonstration and experimental manipulation.
abstract: NAT, HIOMT and melatonin are described in the extra-orbital lacrimal glands. The extra-orbital lacrimal glands of female Syrian hamsters contain higher NAT activity and melatonin levels than those in male glands, while male glands have higher HIOMT activity. Castration did not change melatonin in the lacrimal glands, although NAT and HIOMT activities were altered. The exposure of female hamsters to light in the morning (0600h) was associated with a reduction in both NAT activity and melatonin levels. Porphyrins were not detected in the lacrimal glands of either male or female hamsters.
authors.affiliation: Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284.
authors.forename: M C
authors.initials: MC
authors.lastname: Mhatre
authors.forename: A S
authors.initials: AS
authors.lastname: van Jaarsveld
authors.forename: R J
authors.initials: RJ
authors.lastname: Reiter
mesh_terms: D000121:Acetylserotonin O-Methyltransferase / Q000378:metabolism; D000818:Animals; D001191:Arylamine N-Acetyltransferase / Q000378:metabolism; D006224:Cricetinae; D005260:Female; D007765:Lacrimal Apparatus / Q000032:analysis*; D007931:Leucyl Aminopeptidase / Q000378:metabolism; D008297:Male; D008550:Melatonin / Q000032:analysis*; D008647:Mesocricetus; D011166:Porphyrins / Q000032:analysis
chemical_list: D011166:Porphyrins; D000121:Acetylserotonin O-Methyltransferase; D001191:Arylamine N-Acetyltransferase; D007931:Leucyl Aminopeptidase; D008550:Melatonin