title: Effect of iohexol and diatrizoate on pulmonary arterial pressure following pulmonary angiography. A clinical comparison in man.
abstract: A clinical comparison of the effects on pulmonary arterial pressure produced by iohexol and diatrizoate, following selective pulmonary angiography, was made in 17 patients with a normal pressure before the injection of the contrast medium. A double blind crossover study was performed and each contrast medium was administered in random order. The pulmonary arterial pressure was continuously recorded before, during and after the injection for 3 minutes. The effect of iohexol on the pulmonary arterial pressure was significantly less than that of diatrizoate. The results indicated that iohexol should be better tolerated than diatrizoate and therefore a safer contrast medium for selective pulmonary angiography.
authors.affiliation: Department of Radiology, Nippon Medical School, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tajima
authors.forename: T
authors.initials: T
authors.lastname: Kumazaki
authors.forename: N
authors.initials: N
authors.lastname: Tajima
authors.forename: K
authors.initials: K
authors.lastname: Ebata
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects*; D003973:Diatrizoate / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007472:Iohexol / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011859:Radiography
chemical_list: D003973:Diatrizoate; D007472:Iohexol