Simple determination of ranitidine in dosage forms by in-phase selective AC polarography.
A new AC polarographic method for the determination of pharmaceutical forms of ranitidine is proposed, based on the electroactivity of the ranitidine nitro group. Individual and composite assays as well as recovery studies are described. Results show adequate precision and accuracy. Sample preparation is easy and no excipient separation is required.
Squella
J A
JA
Universidad de Chile, Facultad de Ciencias Quimicas y Farmaceuticas, Santiago.
Zuñiga
L A
LA
Lemus
I
I
Nuñez-Vergara
L J
LJ
D004304:Dosage Forms; D004563:Electrochemistry; D011048:Polarography; D011899:Ranitidine / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D004304:Dosage Forms; D011899:Ranitidine