Studies on some kinetic parameters of aminotransferases in tissues of the snail, Pila globosa (Swainson) during malathion intoxication.
The aspartate and alanine aminotransferases in the tissues of the snail, Pila globosa showed high catalytic potentials (low Km and high Vmax) during malathion exposure in vivo. In vitro addition of different concentrations of malathion did not influence aminotransferase activity. The results are discussed in relation to the regulative influence of the intracellular environment of the cell.
Sahib
I K
IK
Department of Neurology, University of Mississippi, Medical Center, Jackson.
Rao
K R
KR
D000410:Alanine Transaminase / Q000378:metabolism*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D004789:Enzyme Activation / Q000187:drug effects; D066298:In Vitro Techniques; D007700:Kinetics; D008294:Malathion / Q000633:toxicity*; D012908:Snails / Q000187:drug effects* / Q000201:enzymology
D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D008294:Malathion