Changes in renal function following delivery of the lamb by caesarean section.
Six lambs were delivered by caesarean section at 139 to 145 days of gestation. Birth was associated with a rise in glomerular filtration rate from 4.81 +/- 0.62 to 5.90 +/- 0.74 ml/min and a transient natriuresis secondary to a fall in fractional sodium reabsorption from 93.1 +/- 3.94 to 88.3 +/- 2.29%. This study indicates that in the immediate postnatal period, glomerulotubular balance is disturbed.
Smith
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School of Physiology and Pharmacology, University of New South Wales, Sydney, Australia.
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D000818:Animals; D000831:Animals, Newborn; D002585:Cesarean Section; D005260:Female; D005919:Glomerular Filtration Rate; D007668:Kidney / Q000502:physiology*; D009318:Natriuresis; D011247:Pregnancy; D012016:Reference Values; D012756:Sheep / Q000502:physiology*