Activity of several antibiotics against staphylococci.
The activity of ten antibiotics was determined against methicillin-susceptible and methicillin-resistant Staphylococcus isolates. Vancomycin, cephalothin, rifampicin and clindamycin were the most active antimicrobial agents. Considering the potential toxicity problems of vancomycin and the ability of clindamycin to increase opsonization, our data suggest that clindamycin may have a potential therapeutic use in the treatment of infections caused by methicillin-resistant staphylococci.
Aceti
A
A
Tropical and Infectious Diseases Clinical Institute, University of Rome, Italy.
Attanasio
R
R
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002512:Cephalothin / Q000494:pharmacology; D002981:Clindamycin / Q000494:pharmacology; D008712:Methicillin / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects* / Q000302:isolation & purification; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002981:Clindamycin; D014640:Vancomycin; D008712:Methicillin; D002512:Cephalothin