Antibody to tumor necrosis factor (TNF) reduces endotoxin fever.
Antibody to tumor necrosis factor (TNF), injected intravenously, reduced endotoxin fever in the rabbit. The fever-reducing effect was apparent in the latter half of the febrile response.
Nagai
M
M
Department of Physiology, Medical University of Yamanashi, Japan.
Saigusa
T
T
Shimada
Y
Y
Inagawa
H
H
Oshima
H
H
Iriki
M
M
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000937:Antigen-Antibody Reactions; D004731:Endotoxins / Q000494:pharmacology*; D005334:Fever / Q000503:physiopathology*; D011817:Rabbits; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors / Q000276:immunology / Q000502:physiology*
D000911:Antibodies, Monoclonal; D004731:Endotoxins; D014409:Tumor Necrosis Factor-alpha