Meprobamate poisoning, hypotension and the Swan-Ganz catheter.
A case is described in which voluntary ingestion of 72 g meprobamate (mpb) was complicated by shock ascribed to cardiac failure and vasodilation, documented by hemodynamic monitoring. Forced diuresis and cardiac inotropic support were added to the therapy. We recommend Swan-Ganz monitoring in any case of mpb overdosage associated with hypotension and suggest that forced diuresis is not contraindicated if appropriate assessment of the patient's hemodynamic condition is performed.
Eeckhout
E
E
Department of Internal Medicine, Akademisch Ziekenhuis Vrije Universiteit Brussel, Belgium.
Huyghens
L
L
Loef
B
B
Maes
V
V
Sennesael
J
J
D000328:Adult; D002407:Catheterization, Swan-Ganz; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000139:chemically induced* / Q000503:physiopathology; D008620:Meprobamate / Q000506:poisoning*; D008991:Monitoring, Physiologic / Q000295:instrumentation; D012770:Shock, Cardiogenic / Q000139:chemically induced / Q000503:physiopathology
D008620:Meprobamate