title: [Kinetic study of thrombocytopenia associated with HIV infection].
abstract: In the last 2 years, 46 cases of HIV-induced pure thrombocytopenias have been studied, using either autologous 111 In-labeled platelets and/or homologous 51Cr-labeled platelets. The most interesting data seem to be: more than 50% of the cases were observed in young, drug addicts, a population statistically different from the general epidemiological survey of AIDS; in most the cases, thrombocytopenia was an isolated symptom with no other symptoms due to the HIV infection, or any other hematological abnormality; cortico steroids and immunoglobulins were either inefficient or only temporarily useful. In contrast splenectomy was efficient, at short or middle-term, in 12 cases of the present series; this last fact correlated with the splenic sequestration observed in almost all the cases; the platelet life-span was short in all these patients, except those with AIDS disease and pan myelopathy.
authors.affiliation: Service de Médecine Nucléaire, Hôpital Saint-Louis, Paris, France.
authors.forename: Z
authors.initials: Z
authors.lastname: Bel-Hadj-Ali
authors.forename: V
authors.initials: V
authors.lastname: Dufour
authors.forename: Y
authors.initials: Y
authors.lastname: Najean
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D005260:Female; D006716:Homosexuality; D006801:Humans; D007700:Kinetics; D008297:Male; D019966:Substance-Related Disorders; D013921:Thrombocytopenia / Q000209:etiology*
vernacular_title: Etude cinétique des thrombocytopénies associées à l'infection virale HIV.