The use of intravitreal thrombin to control hemorrhage during retinectomy.
The intravitreal infusion of thrombin at the time of retinectomy or retinotomy is an effective method of controlling hemorrhage from the cut edges of retina. Thrombin reduced the bleeding time from 118 +/- 24 seconds to 7 +/- 10 seconds following retinectomy. The intravitreal infusion of thrombin may possibly have an advantage over diathermy since less tissue destruction occurs.
Glaser
B M
BM
Wilmer Ophthalmological Institute, Johns Hopkins University, School of Medicine, Baltimore, MD 21205.
D001760:Bleeding Time; D005123:Eye / Q000098:blood supply; D005128:Eye Diseases / Q000517:prevention & control*; D006470:Hemorrhage / Q000517:prevention & control*; D006801:Humans; D007267:Injections; D007431:Intraoperative Complications; D011183:Postoperative Complications; D012160:Retina / Q000601:surgery*; D013917:Thrombin / Q000008:administration & dosage* / Q000627:therapeutic use; D014822:Vitreous Body
D013917:Thrombin