Role of hypovolemia in dialysis-induced hypotension.
Blood volume was measured continuously during hemodialysis using the authors' hematocrit continuous measurement system in an attempt to determine any relationship between dialysis-induced hypotension with acute onset and blood volume. Hypotension resulted approximately 3 h into dialysis in the present study. This point in time was that at which blood volume was more than 5% above the minimum level during the dialysis treatment, and in some patients it was more than 10% over the minimum level of blood volume. At the time dialysis-induced hypotension occurred or before, there was no sharp decrease in blood volume nor any change in the plasma refilling rate. This suggested that this hypotension is caused by a sudden breakdown of the blood pressure support mechanism compensating for decreased blood volume.
Maeda
K
K
Nagoya University Branch Hospital, Japan.
Morita
H
H
Shinzato
T
T
Vega
B V
BV
Kobayakawa
H
H
Ishihara
T
T
Inagaki
H
H
Igarashi
I
I
Kitano
T
T
D001810:Blood Volume; D005260:Female; D006400:Hematocrit; D006801:Humans; D007022:Hypotension / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*