[Chloroquine retinopathy: preventable by monitoring the maximum daily dose].
Decisive for the development of chloroquine retinopathy is not the total cumulative dose. Recent findings indicate that retinopathy develops if daily dosages are too high. Therefore, daily dosages of 4 mg chloroquine/kg ideal body weight and 6.5 mg hydroxychloroquine/kg body weight, respectively, should not be exceeded. If these maximum daily dosages are observed, long-term therapy over periods of months or even years seems to be safe.
Ochsendorf
F R
FR
Zentrum der Dermatologie und Venerologie, J.W. Goethe-Universität Frankfurt/M.
Runne
U
U
D002738:Chloroquine / Q000008:administration & dosage / Q000009:adverse effects*; D004334:Drug Administration Schedule; D006801:Humans; D012164:Retinal Diseases / Q000139:chemically induced* / Q000517:prevention & control
D002738:Chloroquine
Chloroquin-Retinopathie: vermeidbar durch Beachtung der maximalen Tagesdosis.