title: Tamponade due to hemopericardium after streptokinase therapy for pulmonary embolism.
abstract: A 67-year-old man was given intravenous heparin and then streptokinase for an acute severe pulmonary embolism. The next day a large pericardial effusion developed, with tamponade. Aspiration of blood (500 ml) from the pericardial sac produced prompt relief. The possibility of hemopericardium causing tamponade should be considered on unexplained worsening of cardiac status in a patient who has recently received streptokinase for pulmonary embolism or myocardial infarction.
authors.affiliation: Cardiology Section, VA Medical Center, Augusta, GA 30910.
authors.forename: P J
authors.initials: PJ
authors.lastname: Giles
authors.forename: I A
authors.initials: IA
authors.lastname: D'Cruz
authors.forename: H A
authors.initials: HA
authors.lastname: Killam
mesh_terms: D000368:Aged; D002305:Cardiac Tamponade / Q000150:complications*; D004452:Echocardiography; D006801:Humans; D008297:Male; D010490:Pericardial Effusion / Q000139:chemically induced* / Q000175:diagnosis; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011859:Radiography; D013300:Streptokinase / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D013300:Streptokinase