Does acute hyperglycaemia influence heat pain thresholds?
The influence of acute hyperglycaemia on pain sensation was assessed in eight young adult non-diabetic subjects. Acute hyperglycaemia was induced with IV glucose in a double blind fashion, with IV saline as a control. Pain thresholds were assessed by a painful heat stimulus delivered by a Marstock thermode on the thenar eminence. Heat pain thresholds did not significantly alter during either acute hyperglycaemia or the control saline infusion. Previous work demonstrating a lowering of electrical pain thresholds by hyperglycaemia has therefore not been confirmed using a natural painful stimulus.
Chan
A W
AW
Diabetic Clinic, Walton Hospital, Liverpool, UK.
MacFarlane
I A
IA
Bowsher
D R
DR
Wells
J C
JC
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000503:physiopathology*; D008297:Male; D009619:Nociceptors / Q000503:physiopathology*; D010147:Pain Measurement; D012684:Sensory Thresholds; D013697:Thermosensing / Q000502:physiology*
D001786:Blood Glucose