[Effect of alcoholic intoxication of female mice prior to pregnancy on the ultrastructure of neurons in the sensorimotor cortex of the progeny].
Sensorimotor cortex in the offspring of female rats alcoholized in the prepregnancy period revealed signs of delayed neuronal development and dystrophic changes in the neurons especially on the 14th day after birth. In 21-day-old animals the reparative changes increased, but normalization of neuronal ultrastructure was not observed. The dystrophic changes suggest that prenatal brain hypoxia plays an important role in the pathogenesis of alcohol-induced neuronal lesions in the offspring.
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D000818:Animals; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000473:pathology*; D009474:Neurons / Q000648:ultrastructure; D011247:Pregnancy; D051381:Rats; D013003:Somatosensory Cortex / Q000648:ultrastructure*
Vliianie alkogol'noĭ intoksikatsii krys-samok do beremennosti na ul'trastrukturu neĭronov sensomotornoĭ kory u potomstva.