title: [Splenectomy in the treatment of idiopathic thrombopenic purpura in adults. Apropos of 43 cases].
abstract: Case reports of 43 patients with idiopathic thrombocytopenic purpura (ITP) operated upon from 1975 up to the present were analyzed. After revision of therapeutic indications the predictive prognostic factors for splenectomy, essentially the initial response to corticotherapy, were studied. Findings indicated that splenectomy is effective treatment for ITP since permanent total remissions were obtained in 76% with a morbidity of 16% and a mortality of 2%. Emphasis is placed on the need for minute pre-, intra- and post-operative precautions.
authors.affiliation: Service de Chirurgie Générale A, CHR de Rennes, Hôpital Sud.
authors.forename: Y
authors.initials: Y
authors.lastname: Haffaf
authors.forename: J P
authors.initials: JP
authors.lastname: Letoquart
authors.forename: B
authors.initials: B
authors.lastname: Grosbois
authors.forename: G
authors.initials: G
authors.lastname: Lavenac
authors.forename: R
authors.initials: R
authors.lastname: Leblay
authors.forename: A
authors.initials: A
authors.lastname: Mambrini
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011379:Prognosis; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000601:surgery* / Q000628:therapy; D012189:Retrospective Studies; D013156:Splenectomy
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: La splénectomie dans le traitement du purpura thrombopénique idiopathique de l'adulte. A propos de 43 cas.