Visualization of ocular melanoma with N-isopropyl-p-[123I]-iodoamphetamine.
In a patient with ocular melanoma, scintigraphy with N-isopropyl-p-[123I]-iodoamphetamine [( 123I]IMP) clearly delineated the histologically proven ocular lesion. In a tissue distribution study, using the resected specimen, a significantly high accumulation of the radioactivity was confirmed in tumor tissue. Thus, [123I]IMP scintigraphy provided specific localization of an ocular melanoma.
Ono
S
S
Department of Nuclear Medicine and Ophthalmology, Kawasaki Medical School, Kurashiki, Japan.
Fukunaga
M
M
Otsuka
N
N
Nagai
K
K
Morita
K
K
Furukawa
T
T
Muranaka
A
A
Yanagimoto
S
S
Tomomitsu
T
T
Tabuchi
A
A
D000662:Amphetamines; D005123:Eye / Q000000981:diagnostic imaging / Q000473:pathology; D005134:Eye Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D011877:Radionuclide Imaging
D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine