The effects of topical povidone I solution on serum iodide levels and thyroid uptake of 131I in dogs.
Topical application of povidone I solution in dogs has been found to be effective in producing significant elevations in serum iodide concentrations within 2 h after application. Among dogs treated with this preparation 2 h before oral administration of 131I, significant thyroid blocking persisted for at least 72 h.
Moody
K D
KD
Department of Comparative Medicine, Milton S. Hershey Medical Center, Pennsylvania State University, Hershey 17033.
Miller
K L
KL
White
W J
WJ
Hurst
W J
WJ
Lang
C M
CM
D000287:Administration, Topical; D000818:Animals; D004285:Dogs; D005260:Female; D007454:Iodides / Q000097:blood*; D007457:Iodine Radioisotopes / Q000493:pharmacokinetics*; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000008:administration & dosage*; D013961:Thyroid Gland / Q000187:drug effects / Q000378:metabolism*
D007454:Iodides; D007457:Iodine Radioisotopes; D011206:Povidone-Iodine; D011205:Povidone