Plasma catecholamine concentrations--changes after infiltration with local anaesthetic solutions and adrenaline during bat-ear surgery.
Plasma catecholamine concentrations were measured in 12 patients who had bilateral bat-ear surgery following infiltration of each ear with 2 ml 2% lignocaine with adrenaline 1:100,000. Venous blood samples were withdrawn before and at set intervals after infiltration. Plasma adrenaline concentration increased from 0.8 pmol/ml to a peak of 2.2 pmol/ml at 2 minutes after infiltration; this is an increase of 175%. There was no significant change in plasma noradrenaline concentration.
Lew
J K
JK
University Department of Anaesthesia, Leicester Royal Infirmary.
Mobley
K A
KA
Achola
K J
KJ
Smith
G
G
D000293:Adolescent; D000328:Adult; D000772:Anesthesia, Local; D001794:Blood Pressure / Q000187:drug effects; D002395:Catecholamines / Q000097:blood*; D004431:Ear, External / Q000002:abnormalities / Q000601:surgery; D004837:Epinephrine / Q000008:administration & dosage* / Q000097:blood / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage* / Q000494:pharmacology; D009638:Norepinephrine / Q000097:blood
D002395:Catecholamines; D008012:Lidocaine; D009638:Norepinephrine; D004837:Epinephrine