Hepatic veins belong to "the veins of the digestive tube" in the dog.
Pharmacological responsiveness of isolated strips of the canine hepatic veins was investigated. Circular strips showed a low responsiveness to 5-hydroxytryptamine, a low sensitivity to norepinephrine and a high sensitivity to histamine. Longitudinal strips developed greater tensions to norepinephrine than circular strips. An excitatory cholinergic component was demonstrated in contractile responses of longitudinal strips to transmural stimulation. Acetylcholine-induced contraction was potentiated by physostigmine. These results indicate that the hepatic veins belong to the group of "veins of the digestive tube".
Yoshioka
K
K
Department of Pharmacology, Nagoya University School of Medicine, Japan.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002800:Cholinesterase Inhibitors / Q000494:pharmacology; D004064:Digestive System / Q000098:blood supply*; D004285:Dogs; D004558:Electric Stimulation; D005260:Female; D006632:Histamine / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000098:blood supply*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology; D010830:Physostigmine / Q000494:pharmacology; D011224:Prazosin / Q000494:pharmacology; D012039:Regional Blood Flow / Q000187:drug effects; D012701:Serotonin / Q000494:pharmacology
D002800:Cholinesterase Inhibitors; D012701:Serotonin; D001285:Atropine; D006632:Histamine; D010830:Physostigmine; D000109:Acetylcholine; D009638:Norepinephrine; D011224:Prazosin