title: High dose methotrexate therapy: insecure rationale?
authors.affiliation: Department of Pediatrics, University of Texas Health Science Center, Southwestern Medical School, Dallas 75235.
authors.forename: B A
authors.initials: BA
authors.lastname: Kamen
authors.forename: N J
authors.initials: NJ
authors.lastname: Winick
mesh_terms: D004351:Drug Resistance; D005493:Folic Acid Antagonists; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage* / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy*; D013940:Thymidylate Synthase / Q000032:analysis
chemical_list: D005493:Folic Acid Antagonists; D013940:Thymidylate Synthase; D008727:Methotrexate