Dysgonic fermenter 3-associated gastrointestinal disease in a patient with common variable hypogammaglobulinemia.
A gram-negative bacteria designated DF-3 was cultured on multiple occasions from stool samples of a patient with common variable hypogammaglobulinemia and chronic diarrhea. Antibiotic therapy resulted in elimination of the organism and resolution of the patient's symptoms. DF-3 has not been linked previously to human disease; because of its fastidious growth characteristics and unique isolation requirements, it may be a rarely identified cause of diarrhea and other gastrointestinal symptoms in immunocompromised patients.
Wagner
D K
DK
Metabolism Branch, National Institutes of Health, Bethesda, Maryland.
Wright
J J
JJ
Ansher
A F
AF
Gill
V J
VJ
D000361:Agammaglobulinemia / Q000150:complications*; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy / Q000209:etiology*; D003967:Diarrhea / Q000209:etiology; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology*; D006089:Gram-Negative Anaerobic Bacteria / Q000302:isolation & purification*; D006801:Humans; D013752:Tetracycline / Q000627:therapeutic use
D013752:Tetracycline