[Metabolic effects of succinic and nicotinic acids in emotional pain stress].
In experiments on rats it was shown that administration of succinic and nicotinic acids in doses of 30 and 4 mg/kg for 5 days elevated pyruvic acid level and changed catecholamine balance in tissues of the aorta and heart. The administration of the drugs to rats with current-induced stress partially eliminated unfavourable shifts in carbohydrate metabolism and catecholamine balance in the aortic and cardiac tissues. Succinic acid had more pronounced metabolic activity.
Rachkov
A K
AK
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001011:Aorta / Q000187:drug effects / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D006321:Heart / Q000187:drug effects; D008297:Male; D009206:Myocardium / Q000378:metabolism; D009525:Niacin / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy* / Q000378:metabolism; D051381:Rats; D013315:Stress, Psychological / Q000188:drug therapy* / Q000378:metabolism; D013386:Succinates / Q000627:therapeutic use*; D019802:Succinic Acid; D013997:Time Factors
D013386:Succinates; D009525:Niacin; D019802:Succinic Acid
Metabolicheskie éffekty iantarnoĭ i nikotinovoĭ kislot pri émotsional'no-bolevom stresse.