title: Imipramine and social-vocational adjustment in chronic depression.
abstract: The authors compared the effects of 6 weeks of imipramine treatment with 6 weeks of placebo treatment on social and vocational impairment in chronic depression. Imipramine was associated with significantly greater pre- to posttreatment improvement of social-vocational impairments in chronic depression, suggesting that these impairments may have represented affective symptoms rather than characterologic deficits.
authors.affiliation: Department of Psychiatry, Payne Whitney Psychiatric Clinic, New York Hospital--Cornell Medical Center 10021.
authors.forename: J H
authors.initials: JH
authors.lastname: Kocsis
authors.forename: A J
authors.initials: AJ
authors.lastname: Frances
authors.forename: C
authors.initials: C
authors.lastname: Voss
authors.forename: B J
authors.initials: BJ
authors.lastname: Mason
authors.forename: J J
authors.initials: JJ
authors.lastname: Mann
authors.forename: J
authors.initials: J
authors.lastname: Sweeney
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003866:Depressive Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012917:Social Adjustment; D014937:Work
chemical_list: D007099:Imipramine