title: A discrimination value of serum lipid level on the basis of healthy and diseased persons.
abstract: We have established a discrimination value that classifies serum lipid levels, that is, total cholesterol, phospholipid, triglyceride, and beta-lipoprotein, into normal or abnormal state. The analysis was made using the linear discriminant function based on 720 normal subjects and 294 patients with coronary heart disease and/or diabetes mellitus. Basically, the function denoted as f is a linear combination of the predictor variables x(1),x(2),...,x(n) weighted by w(0),w(1),w(2),...,w(n). First, we obtained a function from the training set that consists of age-matched 204 normals and 204 patients. The predictor variables used are four serum constituents and age. Next, we tested the cross-validation of this function by the remainder of the samples (test set). Finally, we obtained a discrimination value, by which 96.1% of the training set and 96.3% of the test set was correctly classified.
authors.affiliation: Department of Laboratory Medicine, Niigata University, School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Okada
authors.forename: M
authors.initials: M
authors.lastname: Okada
authors.forename: M
authors.initials: M
authors.lastname: Yakata
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D003327:Coronary Disease / Q000097:blood*; D003625:Data Collection; D003627:Data Interpretation, Statistical; D003920:Diabetes Mellitus / Q000097:blood*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012016:Reference Values
chemical_list: D008055:Lipids