Imipramine and social-vocational adjustment in chronic depression.
The authors compared the effects of 6 weeks of imipramine treatment with 6 weeks of placebo treatment on social and vocational impairment in chronic depression. Imipramine was associated with significantly greater pre- to posttreatment improvement of social-vocational impairments in chronic depression, suggesting that these impairments may have represented affective symptoms rather than characterologic deficits.
Kocsis
J H
JH
Department of Psychiatry, Payne Whitney Psychiatric Clinic, New York Hospital--Cornell Medical Center 10021.
Frances
A J
AJ
Voss
C
C
Mason
B J
BJ
Mann
J J
JJ
Sweeney
J
J
D000328:Adult; D002908:Chronic Disease; D003866:Depressive Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012917:Social Adjustment; D014937:Work
D007099:Imipramine