title: The glycosphingolipids of human prostate tissue.
abstract: Neutral glycolipids and gangliosides from surgical samples of benign human prostate tissue were analyzed by chemical, enzymatic and immunostaining procedures. The neutral glycolipids consisted of ceramide mono-, di-, tri- and tetrahexosides of the globo series plus paragloboside. The monosialoganglioside fraction contained GM3 and GM1 plus multiple species of monosialylated lactosamine-containing structures, including sialyl-alpha-2----3paragloboside plus at least two compounds having a non-reducing terminal sialyl alpha 2----6Gal linkage. The disialoganglioside fraction contained GD3 as the major component plus GD1a, GD2 and GD1b. GT1b was the major trisialoganglioside.
authors.affiliation: Department of Pathology, University of Virginia Medical Center, Charlottesville 22908.
authors.forename: T
authors.initials: T
authors.lastname: Shiraishi
authors.forename: M T
authors.initials: MT
authors.lastname: Kinter
authors.forename: S E
authors.initials: SE
authors.lastname: Mills
authors.forename: M C
authors.initials: MC
authors.lastname: Lippert
authors.forename: G S
authors.initials: GS
authors.lastname: Bova
authors.forename: W W
authors.initials: WW
authors.lastname: Young
mesh_terms: D000368:Aged; D002855:Chromatography, Thin Layer; D005732:Gangliosides / Q000032:analysis; D006028:Glycosphingolipids / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019158:N-Acetylneuraminic Acid; D011467:Prostate / Q000032:analysis*; D012794:Sialic Acids / Q000032:analysis
chemical_list: D005732:Gangliosides; D006028:Glycosphingolipids; D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid