[Polymorphism of smooth muscle cells in atheromatous plaques of the human aorta].
The expression of cell cytoskeleton proteins in atheromatous plaques of human aorta was investigated using double immunofluorescence technique and a set of antibodies. It was found that in 4 out of 12 plaques some smooth muscle cells (SMC) were stained by monoclonal antibodies to desmin. No such cells were detected in apparently unaffected aortic intima. In addition to typical SMC and these cells, the cells unstained by antisera to smooth muscle myosin but reacting with monoclonal antibodies to vimentin and SMC surface were revealed in all plaques adjacent to the central fatty mass.
Babaev
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Tararak
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D000328:Adult; D000368:Aged; D001013:Aorta, Thoracic; D001018:Aortic Diseases / Q000473:pathology*; D001161:Arteriosclerosis / Q000473:pathology*; D003598:Cytoskeletal Proteins / Q000032:analysis; D006801:Humans; D066298:In Vitro Techniques; D008875:Middle Aged; D009124:Muscle Proteins / Q000032:analysis; D009131:Muscle, Smooth, Vascular / Q000032:analysis / Q000473:pathology*
D003598:Cytoskeletal Proteins; D009124:Muscle Proteins
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