title: The BB-isoenzyme is a major component of creatine kinase in skin blister fluid.
abstract: We measured levels of creatine kinase and its three isoenzymes in serum and blister fluid from 16 healthy volunteers. The BB-isoenzyme was found to be the predominant form in blister fluid while only the MM isoenzyme was found in serum. The levels of BB-isoenzyme in blister fluid decreased as the blisters aged. The source of BB-isoenzyme in blister fluid is most probably the damaged epidermis.
authors.affiliation: Department of Pathology, University of Helsinki, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Paavonen
authors.forename: H
authors.initials: H
authors.lastname: Aronen
authors.forename: I
authors.initials: I
authors.lastname: Saarelainen
authors.forename: H
authors.initials: H
authors.lastname: Neittaanmäki
authors.forename: I
authors.initials: I
authors.lastname: Hjelm
authors.forename: U
authors.initials: U
authors.lastname: Kiistala
mesh_terms: D000328:Adult; D001768:Blister / Q000201:enzymology*; D001826:Body Fluids / Q000201:enzymology*; D003402:Creatine Kinase / Q000378:metabolism*; D006801:Humans; D007527:Isoenzymes; D008297:Male; D012867:Skin / Q000201:enzymology*
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase