Dopamine receptor agonists: new angularly annulated tricyclic compounds.
In order to study the influence on dopaminergic activity of the exchange of X in rigid dopamine congeners of structure 1, the synthesis of octahydrobenzo [f] trans-quinoxalines (VII c, d) and trans-hexahydro-4H-naphtho[1,2-b][1,4]thiazines (X c, d), is reported.
Perrone
R
R
Dipartimento Farmacochimico, Università di Bari, Italy.
Berardi
F
F
Bettoni
G
G
Tortorella
V
V
D055598:Chemical Phenomena; D002621:Chemistry; D008968:Molecular Conformation; D011810:Quinoxalines / Q000494:pharmacology*; D011954:Receptors, Dopamine / Q000187:drug effects*; D013329:Structure-Activity Relationship; D013843:Thiazines / Q000494:pharmacology*
D011810:Quinoxalines; D011954:Receptors, Dopamine; D013843:Thiazines