title: Does acute hyperglycaemia influence heat pain thresholds?
abstract: The influence of acute hyperglycaemia on pain sensation was assessed in eight young adult non-diabetic subjects. Acute hyperglycaemia was induced with IV glucose in a double blind fashion, with IV saline as a control. Pain thresholds were assessed by a painful heat stimulus delivered by a Marstock thermode on the thenar eminence. Heat pain thresholds did not significantly alter during either acute hyperglycaemia or the control saline infusion. Previous work demonstrating a lowering of electrical pain thresholds by hyperglycaemia has therefore not been confirmed using a natural painful stimulus.
authors.affiliation: Diabetic Clinic, Walton Hospital, Liverpool, UK.
authors.forename: A W
authors.initials: AW
authors.lastname: Chan
authors.forename: I A
authors.initials: IA
authors.lastname: MacFarlane
authors.forename: D R
authors.initials: DR
authors.lastname: Bowsher
authors.forename: J C
authors.initials: JC
authors.lastname: Wells
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000503:physiopathology*; D008297:Male; D009619:Nociceptors / Q000503:physiopathology*; D010147:Pain Measurement; D012684:Sensory Thresholds; D013697:Thermosensing / Q000502:physiology*
chemical_list: D001786:Blood Glucose