title: Periungual hyperpigmentation mimicking Hutchinson's sign associated with minocycline administration.
abstract: An assessment of the occurrence rate of periungual hyperpigmentation with subungual melanoma (Hutchinson's sign) and periungual hyperpigmentation with other subungual lesions has not been published, although periungual hyperpigmentation with a pigmented streak or other pigmented lesion of the nail has been considered pathognomonic for subungual melanoma for a century. We report a case of minocycline hyperpigmentation presenting as a longitudinal pigmented streak of the nail associated with periungual hyperpigmentation. These pigmentary changes could be mistaken for Hutchinson's sign.
authors.affiliation: University of Iceland, Reykjavik.
authors.forename: E
authors.initials: E
authors.lastname: Mooney
authors.forename: R G
authors.initials: RG
authors.lastname: Bennett
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis*; D008911:Minocycline / Q000009:adverse effects*; D009260:Nail Diseases / Q000139:chemically induced*; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000175:diagnosis; D013754:Tetracyclines / Q000009:adverse effects*
chemical_list: D013754:Tetracyclines; D008911:Minocycline