Site specific effects of acute exercise on muscle and adipose tissue metabolism in sedentary female rats.
The effects of endurance exercise on muscle, and adipose tissue metabolism were investigated. Female lean Zucker rats swam for two hours at high intensity. Three groups were examined: pre-exercise control (C), exercised (E) and 24 hours post-exercise (E-24). Exercise increased fat cell lipolysis in the inguinal depot (p less than 0.05) while no effect was detected in the parametrial depot. In contrast, parametrial pad lipoprotein lipase (LPL) activity decreased after exercise with 24 hours post-exercise values being reduced below E and C rats (p less than 0.05). Gastrocnemius LPL activity remained unchanged during exercise while heart LPL increased, E having higher values than C and E-24 (p less than 0.05). Gastrocnemius, but not heart, citrate synthase activity increased with exercise, with E-24 values increased compared to E and C (p less than 0.05). These results demonstrate that adipose tissue's response to exercise is site specific, and suggests a distinct physiological role for different adipose depots. Muscle LPL and citrate synthase activities were modified differently for gastrocnemius and heart, confirming the distinct metabolic response to exercise of these two muscles.
Savard
R
R
Vassar College, Department of Biology, Poughkeepsie, NY 12601.
Smith
L J
LJ
Palmer
J E
JE
Greenwood
M R
MR
D000273:Adipose Tissue / Q000201:enzymology*; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D004734:Energy Metabolism; D005260:Female; D008066:Lipolysis; D008071:Lipoprotein Lipase / Q000097:blood*; D009132:Muscles / Q000201:enzymology*; D009206:Myocardium / Q000201:enzymology; D010807:Physical Endurance; D005082:Physical Exertion; D051381:Rats; D011924:Rats, Zucker; D014280:Triglycerides / Q000097:blood
D001786:Blood Glucose; D014280:Triglycerides; D008071:Lipoprotein Lipase