[Morphometric analysis of the mitochondria of cardiomyocytes in normal states and in postischemic reperfusion].
The analysis of mean values of mitochondrial parameters calculated according to the formula measuring the number of particles in 1 cubic micron has suggested that in cardiomyocytes during reperfusion mitochondria can be described as ellipsoids, whose length is comparable with the length of sarcomeres, and unaffected cardiomyocytes as long bent structures. The volume of one mitochondrion and the surface of mitochondria in 1 cubic micron of sarcoplasm in control and affected cardiomyocytes were identical. The surface of one mitochondrion during postischemic reperfusion was decreased and the number of mitochondria in 1 cubic micron of sarcoplasm was higher than in the control. It is suggested that the damage of cells is associated with an increase in the number and total volume of mitochondria as a result of their lacing and an increase in the volume of each "daughter" mitochondrion up to the volume of the initial mitochondria.
Egorova
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Popov
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IuV
D000818:Animals; D003326:Coronary Circulation; D003327:Coronary Disease / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008929:Mitochondria, Heart / Q000648:ultrastructure*; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains
Morfometricheskiĭ analiz mitokhondriĭ kardiomiotsitov v norme i v khode postishemicheskoĭ reperfuzii.