title: Soy sensitivity: personal observation on 71 children with food intolerance.
abstract: The controversies on the use of soy milk as a substitute in cow's milk intolerance prompted us to study: the incidence of soy sensitivity in a pediatric population (71 children, mean age 5.9 years, 45 boys and 26 girls) with food intolerance: the influence of a prior soy milk feeding on soy sensitivity: the relationship between soy, cow's milk and seed allergy. The patients were subdivided in two groups, one of atopic patients (50 subjects, 28 of which previously fed soy) and the other of non atopic patients (21 subjects, 12 of which previously fed soy). In the atopic group prick and RAST gave positive results to soy in 46% of case, with no difference between subjects fed soy and not. There was a relationship between any and peanut RAST in 82%; between soy and pea in 70%; between soy and cow's milk in 27% of cases. Soy milk challenge was positive in 10 out of 58 children (6 atopic and 4 non atopic); 4 our of 21 atopic patients with a cow's milk intolerance had a positive soy milk challenge: 3 of 10 non atopic patients with cow's milk intolerance were reactive to soy too. 77% of atopic and 90% of non atopic children were responsive both to seeds and soy. It can be concluded that soy sensitivity is rather rare in patients with food intolerance (17.2% of cases) and is not correlated with cow's milk intolerance while is significantly correlated with seeds allergy; there is no difference between atopic and non atopic subjects and between patients previously fed soy and never fed soy.
authors.affiliation: Istituto di Clinica Paediatrica, Università di Milano.
authors.forename: M
authors.initials: M
authors.lastname: Bardare
authors.forename: C
authors.initials: C
authors.lastname: Magnolfi
authors.forename: G
authors.initials: G
authors.lastname: Zani
mesh_terms: D000818:Animals; D010367:Arachis / Q000009:adverse effects; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis / Q000209:etiology; D007223:Infant; D008297:Male; D008892:Milk / Q000009:adverse effects*; D011852:Radioallergosorbent Test; D012882:Skin Tests; D013025:Glycine max / Q000009:adverse effects*