Isolation and structure of a novel pyridine derivative from the Algerian newt, Pleurodeles waltlii.
Since its discovery more than 20 years ago the structure of a strongly fluorescent compound called "pleurodeles blue" has remained unknown. Isolation of this pigment has been carried out by successive column chromatographies including epichlorohydrin-triethanolamine-Sephadex and phospho-Sephadex. The structural elucidation of a novel pyridone N-glycoside, 1-beta-D-glucopyranosylpyrid-2(1H)-one-6-acetic acid, is based on a detailed study of its high-resolution mass spectra, 1H and 13C-NMR spectra and its hydrolysis to yield D-glucose.
Yoshida
T
T
Department of Chemistry, Keio University, Yokohama, Japan.
Iwanami
Y
Y
Bagnara
J T
JT
D000818:Animals; D007814:Larva / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D009705:Nucleosides / Q000302:isolation & purification*; D010860:Pigments, Biological / Q000032:analysis / Q000302:isolation & purification*; D010999:Pleurodeles / Q000378:metabolism*; D011728:Pyridones / Q000302:isolation & purification*; D012455:Salamandridae / Q000378:metabolism*; D012880:Skin Pigmentation
D009705:Nucleosides; D010860:Pigments, Biological; D011728:Pyridones; C056769:1-glucopyranosylpyrid-2(1H)-one-6-acetic acid