title: Toward a strategy for analyzing the auditory middle-latency response waveform.
abstract: The present paper describes for the auditory middle latency response (MLR) an analysis strategy which includes measures of latency, amplitude, waveform width, and area under the waveform. This combination of parameters can adequately describe the MLR and allow reliable and comprehensible comparisons of experimental conditions within and across studies. MLRs were recorded from normal-hearing adults utilizing a variety of recording filter settings, stimulus frequencies and stimulus envelopes. A filter window narrower than 3-300 Hz caused marked distortions in the MLR and significantly affected all parameters. Lower stimulus frequencies yielded significantly larger MLR amplitude, width, and area compared to higher frequencies. Stimulus envelope had no effect on any parameter.
authors.affiliation: Electrophysiology Laboratory, Siegel Institute, Michael Reese Hospital, Chicago, Ill.
authors.forename: T
authors.initials: T
authors.lastname: McGee
authors.forename: N
authors.initials: N
authors.lastname: Kraus
authors.forename: C
authors.initials: C
authors.lastname: Manfredi
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001309:Auditory Threshold / Q000502:physiology; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time