title: [Functioning of the monooxygenase system of the liver in experimental myocardial infarct].
abstract: The experiments on rats have shown that coronary artery ligation reduces the content of microsomal cytochromes P-450 and b5 and causes amidopyrine-N-demethylation and aniline-p-hydroxylation disturbances that persist throughout a 3-week period of myocardial infarction. The investigation of spontaneous lipid peroxidation of microsomal membranes in myocardial infarction has shown that concentration of malonic dialdehyde in microsomal fraction significantly increased by the 7th day after coronary artery ligation, as compared to sham-operated rats.
authors.forename: O R
authors.initials: OR
authors.lastname: Grek
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Borodin
authors.forename: V I
authors.initials: VI
authors.lastname: Sharapov
authors.forename: A A
authors.initials: AA
authors.lastname: Zykov
authors.forename: T A
authors.initials: TA
authors.lastname: Rybakova
mesh_terms: D000632:Aminopyrine; D000814:Aniline Compounds; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003573:Cytochrome b Group / Q000378:metabolism*; D015786:Cytochromes b5; D008862:Microsomes, Liver / Q000201:enzymology*; D009203:Myocardial Infarction / Q000201:enzymology*; D051381:Rats
chemical_list: D000814:Aniline Compounds; D003573:Cytochrome b Group; D000632:Aminopyrine; D015786:Cytochromes b5; D003577:Cytochrome P-450 Enzyme System; C023650:aniline
vernacular_title: Funktsionirovanie monooksigenaznoĭ sistemy pecheni pri éksperimental'nom infarkte miokarda.