Familial leiomyomatosis cutis et uteri (Reed's syndrome).
We report a large family with leiomyomatosis cutis et uteri. Sixty-four percent of the females were involved; 18% had only uterine myomas, 10% had only cutaneous piloleiomyomas, and 36% had both. Five patients (45%) had to have an hysterectomy before age 35. Management of female patients having leiomyomatosis cutis should include a periodical gynecological examination in order to rule out the presence of uterine myomas.
García Muret
M P
MP
Servicio de Dermatología, Hospital de Sant Pau, Barcelona, Spain.
Pujol
R M
RM
Alomar
A
A
Calaf
J
J
de Moragas
J M
JM
D000328:Adult; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007044:Hysterectomy; D007889:Leiomyoma / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology; D014594:Uterine Neoplasms / Q000235:genetics* / Q000473:pathology