[Metabolism of prostaglandins in the rat liver during ethanol withdrawal].
The 9-month intake of a 5% ethanol solution as a source of fluid resulted in the essential fatty acid deficiency, a decrease in the prostaglandins E and F2 alpha level and in the activities of the corresponding prostaglandin synthetases and linoleyl-CoA desaturases in the rat liver. Eight days after ethanol withdrawal the indices of prostaglandin metabolism become normal, whereas the arachidonic acid concentration and the linoleyl-CoA desaturase activity increase.
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VU
D000437:Alcoholism / Q000378:metabolism*; D000818:Animals; D000431:Ethanol / Q000009:adverse effects*; D005227:Fatty Acids / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D011453:Prostaglandins / Q000378:metabolism*; D051381:Rats; D013375:Substance Withdrawal Syndrome / Q000378:metabolism*
D005227:Fatty Acids; D011453:Prostaglandins; D000431:Ethanol
Obmen prostaglandinov v pecheni krys posle otmeny étanola.