[Effect of quinazopyrine on the process of reparative regeneration].
The effect of quinazopyrine on skin wound healing in rats was studied. Quinazopyrine was found to stimulate synthesis of nucleic acids, maturation of fibroblasts and to increase mechanical strength of the postoperative scar. This effect retains in animals with alloxan-induced diabetes. The wound-healing activity of quinazopyrine was higher than that of methyluracil, dimexide, pentoxyl, sodium nucleinate, potassium orotate and riboxine.
Stets
V R
VR
Dunaev
V V
VV
Mazur
I A
IA
Siniak
R S
RS
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000150:complications; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D011799:Quinazolines / Q000008:administration & dosage / Q000494:pharmacology* / Q000633:toxicity; D051381:Rats; D012867:Skin / Q000187:drug effects; D012879:Skin Physiological Phenomena; D013207:Staphylococcal Skin Infections / Q000188:drug therapy; D013268:Stimulation, Chemical; D014945:Wound Healing / Q000187:drug effects*; D014946:Wound Infection / Q000188:drug therapy
D011799:Quinazolines; C056947:quinazopyrine
Vliianie khinazopirina na protsessy reparativnoĭ regeneratsii.