Effect of iohexol and diatrizoate on pulmonary arterial pressure following pulmonary angiography. A clinical comparison in man.
A clinical comparison of the effects on pulmonary arterial pressure produced by iohexol and diatrizoate, following selective pulmonary angiography, was made in 17 patients with a normal pressure before the injection of the contrast medium. A double blind crossover study was performed and each contrast medium was administered in random order. The pulmonary arterial pressure was continuously recorded before, during and after the injection for 3 minutes. The effect of iohexol on the pulmonary arterial pressure was significantly less than that of diatrizoate. The results indicated that iohexol should be better tolerated than diatrizoate and therefore a safer contrast medium for selective pulmonary angiography.
Tajima
H
H
Department of Radiology, Nippon Medical School, Tokyo, Japan.
Kumazaki
T
T
Tajima
N
N
Ebata
K
K
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects*; D003973:Diatrizoate / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007472:Iohexol / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011859:Radiography
D003973:Diatrizoate; D007472:Iohexol