Simultaneous monitoring of coronary blood flow and 31P NMR detected myocardial metabolites.
We report a method of dynamically measuring coronary blood flow in lambs, while simultaneously monitoring cardiac phosphate metabolism with 31P NMR at 81 MHz. This method uses an ultrasonic transit time probe in conjunction with a 4.7-T CSI spectrometer with a 33-cm magnet bore.
Portman
M A
MA
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892.
James
S
S
Heineman
F W
FW
Balaban
R S
RS
D000818:Animals; D003326:Coronary Circulation; D004734:Energy Metabolism; D009682:Magnetic Resonance Spectroscopy; D008991:Monitoring, Physiologic / Q000379:methods*; D009206:Myocardium / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism*; D012756:Sheep
D010710:Phosphates