title: Hb J-Cordoba [alpha 2A beta 2(95)(FG2)Lys----Met]. A new Hb variant found in Argentina.
abstract: Hb J-Cordoba [alpha 2A beta 2(95)(FG2)Lys----Met], is one of the few hemoglobin variants discovered in Argentina. The structure and functional abnormalities are described. Hb J-Cordoba exhibits a slightly increased oxygen affinity, low cooperativity, and normal interaction with heterotropic cofactors.
authors.affiliation: INSERM U.91, UA CNRS 607, Hp Henri Mondor, Créteil, France.
authors.forename: J
authors.initials: J
authors.lastname: Bardakdjian
authors.forename: J
authors.initials: J
authors.lastname: Kister
authors.forename: M D
authors.initials: MD
authors.lastname: Rhoda
authors.forename: M
authors.initials: M
authors.lastname: Marden
authors.forename: N
authors.initials: N
authors.lastname: Arous
authors.forename: J
authors.initials: J
authors.lastname: De Leon
authors.forename: M L
authors.initials: ML
authors.lastname: North
authors.forename: C
authors.initials: C
authors.lastname: Lacombe
authors.forename: Y
authors.initials: Y
authors.lastname: Blouquit
authors.forename: C
authors.initials: C
authors.lastname: Castracane
mesh_terms: D000596:Amino Acids / Q000032:analysis*; D001118:Argentina; D001797:Blood Protein Electrophoresis; D005260:Female; D006448:Hemoglobin J / Q000032:analysis*; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D007223:Infant; D010100:Oxygen / Q000097:blood; D012995:Solubility
chemical_list: D000596:Amino Acids; D006455:Hemoglobins, Abnormal; C056328:hemoglobin J Cordoba; D006448:Hemoglobin J; D010100:Oxygen