title: Necrotizing external otitis treated with ciprofloxacin. A case report.
abstract: Necrotizing (malignant) external otitis is a severe infection caused by Pseudomonas aeruginosa which occurs mainly in elderly diabetics or in immuno-depressed patients (Chandler, 1968). The management of this condition requires the association between an aminoglycoside antibiotic and an antipseudomonal beta-lactamic, given parenterally during a 4 to 6 week period. Sometimes it is necessary to continue the therapy for months until there is no evidence of residual disease (Strauss et al., 1982). Ciprofloxacin is a quinolone with antipseudomonal activity which can be taken orally, and it is a useful alternative to the current treatment. The authors report a case of necrotizing external otitis which was successfully treated with ciprofloxacin.
authors.affiliation: Dept. of Otolaryngology, Hospital Clínic of Barcelona.
authors.forename: F
authors.initials: F
authors.lastname: Sabater
authors.forename: J
authors.initials: J
authors.lastname: Mensa
authors.forename: J
authors.initials: J
authors.lastname: Doménech
authors.forename: M
authors.initials: M
authors.lastname: Loncá
authors.forename: M
authors.initials: M
authors.lastname: Carulla
mesh_terms: D000368:Aged; D002939:Ciprofloxacin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009336:Necrosis; D010032:Otitis Externa / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D002939:Ciprofloxacin