Seasonal and hormonal control of pulsatile LH secretion in the dairy goat (Capra hircus).
In Exp. 1, the changes in pulsatile LH secretion at the onset of the breeding season were observed in 20 intact, mature Saanen does. Blood was sampled every 20 min for 6 h each week from the beginning of August until the onset of ovulatory activity, as evidenced by cycles in plasma progesterone. The first doe ovulated at the end of August and all were cycling by the end of September. As the first ovulation approached, LH pulse frequency increased by 67% and mean levels of LH increased by 47%. These changes were progressive rather than abrupt. In Exp. 2, seasonal changes in the inhibition of pulsatile LH secretion by ovarian steroids were studied in ovariectomized Saanen does. The animals were untreated (N = 4) or given subcutaneous oestradiol implants (N = 4) and blood was sampled every 10 min for 6 h, twice during the breeding season and twice during the anoestrous season. In each season, the second series of samples was taken after the animals had been treated with progesterone, administered by intravaginal implants. Season did not significantly affect LH secretion in goats not treated with oestradiol, but LH pulse frequency was 54% lower during the anoestrous season than during the breeding season in oestradiol-treated goats. Mean LH concentrations were affected in the same manner as pulse frequency, but pulse amplitude was increased by oestradiol treatment in both seasons. Progesterone had no detectable effect on LH secretion in either season. In Exp. 3, the response to repeated melatonin injections at a set time after dawn was investigated in 11 oestradiol-treated, ovariectomized goats.(ABSTRACT TRUNCATED AT 250 WORDS)
Chemineau
P
P
I.N.R.A. Station de Physiologie de la Reproduction, Nouzilly, Monnaie, France.
Martin
G B
GB
Saumande
J
J
Normant
E
E
D000818:Animals; D004958:Estradiol / Q000494:pharmacology / Q000502:physiology*; D004971:Estrus; D005260:Female; D006041:Goats / Q000097:blood*; D007986:Luteinizing Hormone / Q000378:metabolism*; D008550:Melatonin / Q000494:pharmacology / Q000502:physiology*; D010052:Ovariectomy; D011374:Progesterone / Q000097:blood; D012621:Seasons; D012636:Secretory Rate
D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone; D008550:Melatonin