Mannose-resistant haemagglutination by Campylobacter pylori.
10 Campylobacter pylori strains were screened for the presence of presumptive colonization factors by measuring cell surface hydrophobicity and haemagglutination. All 8 clinical isolates and 2 reference strains caused haemagglutination of rabbit, human and/or sheep erythrocytes in the presence of mannose. None of the strains expressed a hydrophobic cell surface. In preliminary experiments the haemagglutination could be inhibited with monosialogangliosides suggesting that these strains express sialic acid specific haemagglutinin(s) which could be involved in colonization of mucosal surfaces.
Emödy
L
L
Department of Medical Microbiology, University of Lund, Sweden.
Carlsson
A
A
Ljungh
A
A
Wadström
T
T
D000818:Animals; D002167:Campylobacter / Q000302:isolation & purification / Q000472:pathogenicity*; D004352:Drug Resistance, Microbial; D005756:Gastritis / Q000382:microbiology; D006386:Hemagglutination Tests; D006801:Humans; D008358:Mannose; D011817:Rabbits; D012756:Sheep
D008358:Mannose