Direct electrochemical probes of redox protein and redox enzyme structure and function.
The direct electrochemistry of redox proteins has been achieved at a variety of electrodes, including modified gold and pyrolytic graphite. Careful design of electrode surfaces and electrolyte conditions are required for the attainment of rapid and reversible protein-electrode interaction. Protein-protein complexes can be studied by using selective electrode surfaces. The "well-behaved" electrochemistry of redox proteins can be exploited by coupling the electrode reaction to enzymes for which the redox proteins act as cofactors. The electron-transfer reactions of more complex systems, such as redox enzymes, are now being examined.
Barker
P D
PD
Inorganic Chemistry Laboratory, Oxford University, UK.
Hill
H A
HA
D003580:Cytochromes / Q000378:metabolism; D004563:Electrochemistry; D004579:Electron Transport; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*; D011199:Potentiometry; D011506:Proteins / Q000378:metabolism*
D003580:Cytochromes; D011506:Proteins; D010088:Oxidoreductases