title: Cerebrospinal fluid indoleacetic acid in autistic subjects.
abstract: Cerebrospinal fluid (CSF) levels of the tryptamine metabolite, indoleacetic acid (IAA), have been measured in groups of autistic and control subjects. No significant difference was seen in group mean (+/- SEM) levels of CSF IAA (autistics 5.53 +/- 0.47 ng/ml, N = 10). The finding indicates that central metabolism of the behaviorally active trace amine tryptamine is probably normal in autism.
authors.affiliation: Department of Laboratory Medicine, Yale University School of Medicine, New Haven.
authors.forename: G M
authors.initials: GM
authors.lastname: Anderson
authors.forename: D L
authors.initials: DL
authors.lastname: Ross
authors.forename: W
authors.initials: W
authors.lastname: Klykylo
authors.forename: F C
authors.initials: FC
authors.lastname: Feibel
authors.forename: D J
authors.initials: DJ
authors.lastname: Cohen
mesh_terms: D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000134:cerebrospinal fluid*; D002648:Child; D006801:Humans; D007210:Indoleacetic Acids / Q000134:cerebrospinal fluid*; D007231:Infant, Newborn
chemical_list: D007210:Indoleacetic Acids; C030737:indoleacetic acid