Acute acalculous cholecystitis--experimental and clinical observations.
Induction of acute acalculous cholecystitis was studied in dogs. Designed models included ligation of the cystic artery and/or duct separately or combined and injection of colonic flora into the gallbladder. Cholecystectomy was performed 72 h later. Histological studies of the gallbladders and bile cultures demonstrated various degrees of cholecystitis, the severest form occurring as a result of cystic artery ligation, whereas the mildest was produced by injection of bacteria. Secondary infection was a constant feature of our experimental models.
Shaked
G
G
Department of Surgery C, Soroka Medical Center, Beer Sheva, Israel.
Ovnat
A
A
Eyal
A
A
Fraser
D
D
Klain
J
J
Peiser
J
J
Charuzi
I
I
D000208:Acute Disease; D000818:Animals; D002763:Cholecystectomy; D002764:Cholecystitis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D002767:Cholecystostomy; D003549:Cystic Duct; D004195:Disease Models, Animal; D004285:Dogs; D008026:Ligation