[Dynamics of the lipid peroxidation process in the body of patients with manic-depressive psychosis].
Using gas chromatography the authors have studied the time course of lipid peroxidation (LPO) in patients with manic depressive psychosis (a depressive phase) during a course of antidepressive therapy. The results indicate that the levels of LPO in young patients (up to 30 years) with a disease standing of up to 5 years are significantly higher than in age-matched controls whereas with increasing duration of the disease the levels of this parameter decrease and in elderly patients (over 50 years) with a longer duration of the disease (over 15 years) this parameter is significantly lower than in age-matched controls. A decrease of LPO is particularly pronounced in a bipolar course of manic depressive psychosis.
Kovaleva
E S
ES
Orlov
O N
ON
Piatnitskiĭ
A N
AN
Beliaev
B S
BS
Erin
A N
AN
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001714:Bipolar Disorder / Q000378:metabolism* / Q000628:therapy; D001944:Breath Tests; D002849:Chromatography, Gas; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000378:metabolism*; D008875:Middle Aged; D010084:Oxidation-Reduction; D010420:Pentanes / Q000032:analysis
D008054:Lipid Peroxides; D010420:Pentanes; C033353:pentane
Dinamika protsessov perekisnogo okisleniia lipidov v organizme bol'nykh maniakal'no-depressivnym psikhozom.