Red cell antibodies in thalassemia hemoglobinopathy patients.
One hundred sixty-four previously transfused patients with T/H disease received one to 136 transfusions with an average of 14.65. Immunization to red blood cell occurred in 14 patients (8.5%). Among these, 11 patients had alloantibody, one patient had autoimmune antibody, and two patients had both alloantibody and autoimmune antibody. The naturally occurring antibody (anti-Leb) was observed in pretransfused blood samples of two patients (1.2%). Most red cell immunization seemed to occur in the early period of blood transfusion.
Tardtong
P
P
Department of Pathology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Ratanasirivanich
P
P
Chiewsilp
P
P
Hathirat
P
P
D002675:Child, Preschool; D004912:Erythrocytes / Q000276:immunology*; D006453:Hemoglobinopathies / Q000276:immunology*; D006801:Humans; D007518:Isoantibodies / Q000032:analysis*; D012189:Retrospective Studies; D013789:Thalassemia / Q000276:immunology*; D065227:Transfusion Reaction
D007518:Isoantibodies