[Pleurisy and sarcoidosis].
Two cases of sarcoidosis associated with pleurisy are presented. The pleural effusion had the same characteristics in both cases. Histology showed non-caseating epithelioid and giant cell granulomas in the parietal pleura. The first case was consistent with sarcoid pleurisy, but in the second case culture of a pleural biopsy specimen fragment demonstrated tuberculous pleurisy. Pleurisy may complicate sarcoidosis in about 2.5% of patients, notably in extensive pulmonary sarcoidosis with extrathoracic lesions. The clinical presentation and the appearance of the pleural fluid are varied. In most cases, a predominantly lymphocytic sero-fibrinous exudate is present. Thorough bacteriological studies, best performed on pleural tissue cultures, must follow the discovery of non-caseating tuberculoid granulomas which are also found in tuberculous pleurisy. Among the various pathogenetic theories considered, the immune reaction theory deserves special mention.
Natali
F
F
Hôpital d'Instruction des Armées Percy, Service de Pneumologie, Clamart.
Heyraud
J D
JD
Vaylet
F
F
Ben Nasser
A
A
Maurel
C
C
Allard
P
P
D000328:Adult; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000473:pathology; D010998:Pleurisy / Q000209:etiology* / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology
Pleurésie et sarcoïdose.