title: Results of the management of craniopharyngioma in children. An endocrinological approach to the treatment.
abstract: The treatment results of 21 (1972-1982) patients with craniopharyngioma are reported who were treated either by surgery alone or by surgery and radiation therapy. The authors reviewed 14 patients (67%) who were less than 18 years of age at the time of surgery. The eradication was thought to be total in 7 children and subtotal in 7. Radiation was given as part of the initial therapy to 5 children after total excision and to 3 after subtotal removal. There were 2 postoperative deaths. All of the children suffered postoperative hormonal deficiencies. The results of this study indicate that total and subtotal removal followed by RT is an acceptable treatment for craniopharyngioma. Endocrine-deficient children, if treated properly, do well in terms of survival.
authors.affiliation: Department of Neurosurgery, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul, Korea.
authors.forename: J K
authors.initials: JK
authors.lastname: Kang
authors.forename: J U
authors.initials: JU
authors.lastname: Song
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003397:Craniopharyngioma / Q000150:complications / Q000503:physiopathology / Q000532:radiotherapy / Q000601:surgery*; D004700:Endocrine System Diseases / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000188:drug therapy / Q000209:etiology; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000503:physiopathology / Q000532:radiotherapy / Q000601:surgery*; D011183:Postoperative Complications
chemical_list: D013006:Growth Hormone