title: Thermospray liquid chromatographic-mass spectrometric method for the analysis of metribuzin and its metabolites.
abstract: A thermospray liquid chromatographic-mass spectrometric (TSP LC-MS) method has been developed for the analysis of the herbicide metribuzin and its three major metabolites in plant tissue. Metribuzin and its metabolites exhibited widely varying sensitivities in positive-ion TSP, with metribuzin being the most sensitive and deaminated diketo metribuzin being the least sensitive. All four compounds of interest were detected in an extract of a soybean plant which had been treated with metribuzin.
authors.affiliation: Laboratory of Molecular Biophysics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709.
authors.forename: C E
authors.initials: CE
authors.lastname: Parker
authors.forename: A V
authors.initials: AV
authors.lastname: Geeson
authors.forename: D E
authors.initials: DE
authors.lastname: Games
authors.forename: E D
authors.initials: ED
authors.lastname: Ramsey
authors.forename: E O
authors.initials: EO
authors.lastname: Abusteit
authors.forename: F T
authors.initials: FT
authors.lastname: Corbin
authors.forename: K B
authors.initials: KB
authors.lastname: Tomer
mesh_terms: D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D006540:Herbicides / Q000032:analysis* / Q000493:pharmacokinetics; D013058:Mass Spectrometry; D010936:Plant Extracts / Q000032:analysis; D014227:Triazines / Q000032:analysis* / Q000493:pharmacokinetics
chemical_list: D006540:Herbicides; D010936:Plant Extracts; D014227:Triazines; C009235:metribuzin