title: Ventricular-brain ratio and life course of illness in patients with affective disorder.
abstract: The relationship between ventricular-brain ratio (VBR) on computed tomography of the brain and life course of illness was assessed in 59 hospitalized patients with recurrent affective disorder. In contrast to the implications of some, but not all, prior studies. VBR was not positively related to episode frequency, severity, pattern, or chronicity. In fact, when analyzed by sex, in both males and females, VBR was inversely related to several measures of illness chronicity.
authors.affiliation: Anxiety Disorder Research, University of Washington, Seattle.
authors.forename: P P
authors.initials: PP
authors.lastname: Roy-Byrne
authors.forename: R M
authors.initials: RM
authors.lastname: Post
authors.forename: C H
authors.initials: CH
authors.lastname: Kellner
authors.forename: R T
authors.initials: RT
authors.lastname: Joffe
authors.forename: T W
authors.initials: TW
authors.lastname: Uhde
mesh_terms: D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000473:pathology* / Q000523:psychology; D001921:Brain / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology*; D003866:Depressive Disorder / Q000473:pathology* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed