Acutely induced shift in ocular dominance during brief monocular exposure: effects of cortical noradrenaline infusion.
Acutely anesthetized and paralysed kittens were monocularly exposed to TV shows for approximately 20 h, throughout which the visual cortex received a direct infusion of (-)-noradrenaline (NA) or (+)-NA. The ocular dominance distribution was found shifted toward the exposed eye in the (-)-NA-infused cortex, but not in control cortex, i.e. the drug-free kitten cortex, the kitten cortex infused with (+)-NA, and the (-)-NA-infused adult cortex. Noise patterns on the same TV screen also failed to induce a shift in the (-)-NA-infused kitten cortex. It is concluded that shift in ocular dominance takes place in kittens, even under general anesthesia and paralysis, when cortical (-)-NA infusion and pattern vision through one eye are combined.
Imamura
K
K
Smith-Kettlewell Eye Research Foundation, San Francisco, CA 94115.
Kasamatsu
T
T
D000375:Aging; D000818:Animals; D002415:Cats; D004292:Dominance, Cerebral / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology*; D012016:Reference Values; D014793:Visual Cortex / Q000187:drug effects / Q000254:growth & development / Q000502:physiology*; D014794:Visual Fields; D014796:Visual Perception / Q000187:drug effects*
D009638:Norepinephrine