[Sequential analysis of specific IgE and IgG titres as a function of the cumulated doses of venoms injected in allergies to Hymenoptera and correlation with specific IgE, clinical manifestations and skin tests].
The numbers of IgE and specific IgE in ten desensitized to wasp-venom patients are retrospectively analysed, in order to study their variation according to the cumulated dose of administered venom during the desensitization (mean-time 18.4 months). Our results allow to find after a latency period, a growth of the specific IgE number, then their gradual decrease, while the specific IgE number gradually rises to reach a deal-level.
Hutt
N
N
CHU Strasbourg.
Hutt-Kempf
E
E
Thierry
R
R
Pauli
G
G
Guilloux
L
L
D000328:Adult; D001514:Bee Venoms / Q000008:administration & dosage / Q000276:immunology*; D003888:Desensitization, Immunologic; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000276:immunology* / Q000628:therapy; D007073:Immunoglobulin E / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012882:Skin Tests; D014862:Wasp Venoms / Q000008:administration & dosage / Q000276:immunology*
D001514:Bee Venoms; D007074:Immunoglobulin G; D014862:Wasp Venoms; D007073:Immunoglobulin E
Analyse séquentielle des titres d'IgE et d'IgG spécifiques en fonction des doses cumulées de venin injectées dans les allergies aux hyménoptères et corrélation entre IgE spécifique, manifestations cliniques et tests cutanés.