title: Neurologic manifestations associated with hypothyroidism in four dogs.
abstract: Hypothyroidism was believed responsible for peripheral and central neurologic abnormalities in 4 dogs. Clinical signs consisted of abnormalities of gait and postural reactions and dysfunction of multiple cranial nerves in all 4 dogs. Circling, hypermetria, and spontaneous verticle nystagmus were observed in some of the dogs. Hypothyroidism was diagnosed in all 4 dogs on the basis of low resting serum thyroxine concentration and inadequate response to thyroid stimulating hormone. After thyroid hormone supplementation, resolution of neurologic abnormalities was complete in 2 dogs and partial in the other 2 dogs.
authors.affiliation: Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602.
authors.forename: P
authors.initials: P
authors.lastname: Bichsel
authors.forename: G
authors.initials: G
authors.lastname: Jacobs
authors.forename: J E
authors.initials: JE
authors.lastname: Oliver
mesh_terms: D000818:Animals; D001921:Brain / Q000000981:diagnostic imaging; D004283:Dog Diseases / Q000209:etiology*; D004285:Dogs; D004576:Electromyography / Q000662:veterinary; D005072:Evoked Potentials, Auditory; D005260:Female; D007037:Hypothyroidism / Q000150:complications / Q000662:veterinary*; D008297:Male; D009422:Nervous System Diseases / Q000209:etiology / Q000662:veterinary*; D011877:Radionuclide Imaging; D013960:Thyroid Function Tests / Q000662:veterinary; D013961:Thyroid Gland / Q000000981:diagnostic imaging