Variant of atelosteogenesis? Report of a 20-week fetus.
We report on a 20-week fetus with manifestations similar, but not identical, to those of atelosteogenesis. The present fetus had rhizomelic micromelia with absence of ossification in the humerus, radius, ulna, and cervical and upper thoracic vertebral bodies; coronal clefts in the ossified thoracic vertebral bodies; and talipes equinovarus. The physes were relatively normal on histologic examination.
Herzberg
A J
AJ
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710.
Effmann
E L
EL
Bradford
W D
WD
D004413:Dysostoses / Q000235:genetics; D004687:Enchondromatosis / Q000235:genetics*; D005260:Female; D005315:Fetal Diseases; D005865:Gestational Age; D006801:Humans; D008297:Male; D010009:Osteochondrodysplasias / Q000235:genetics*; D011247:Pregnancy