title: Pseudallescheria boydii brain abscess. Complication of an intravenous catheter.
abstract: An adult patient survived a brain abscess with Pseudallescheria boydii. She received intraventricular miconazole, 20 mg every 72 hours (minimal inhibitory concentration = 0.4 microgram/ml), and surgery. The abscess resulted from an infected central venous catheter (Port-A-Cath) and steroid therapy. Miconazole caused a ventriculitis. There are 12 reported cases of P. boydii brain abscesses from 1965 to 1985 with only two survivors.
authors.affiliation: Infectious Disease Department, University of California, Irvine.
authors.forename: R E
authors.initials: RE
authors.lastname: Pérez
authors.forename: M
authors.initials: M
authors.lastname: Smith
authors.forename: J
authors.initials: J
authors.lastname: McClendon
authors.forename: J
authors.initials: J
authors.lastname: Kim
authors.forename: N
authors.initials: N
authors.lastname: Eugenio
mesh_terms: D000328:Adult; D001203:Ascomycota / Q000302:isolation & purification*; D001922:Brain Abscess / Q000209:etiology* / Q000628:therapy; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008825:Miconazole / Q000627:therapeutic use; D009181:Mycoses / Q000209:etiology* / Q000628:therapy; D011541:Pseudallescheria / Q000302:isolation & purification*
chemical_list: D008825:Miconazole