Nuclear medicine studies of aging--II. Femoral vessel uptake of 99mTc-diphosphonates vs age.
Bone images obtained after use of 99mTc-MDP were examined for activity presumed to be present in the femoral vessels. The criteria for this extraosseous uptake were: present on anterior views of the thighs, located medial to the femurs, extended outward and downward, approximately linear and continuous, and present on both thighs. Each image was graded as zero (not visible), one plus (barely detectable) and two plus (readily visualized). Using the mean age of each grouping (20-29 years depicted as age 25), the percent positive were noted to closely correlate with age. The earliest positive detected was in a 24 year old male; by age 80 years and greater, over 93% of the cases showed 1+ or 2+ activity. In addition, the average score increased linearly with age. These findings were correlated with literature data on femoral artery diameter and stiffness, and with information on aortic calcification.
Spencer
R P
RP
Department of Nuclear Medicine, University of Connecticut Health Center, Farmington 06032.
Barton
P A
PA
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging*; D005268:Femoral Vein / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013669:Technetium Tc 99m Medronate
D013669:Technetium Tc 99m Medronate