title: Population studies in northern Sweden. XIII. The 6-phosphogluconate dehydrogenase polymorphism.
abstract: Frequencies of the 6-phosphogluconate dehydrogenase (6-PGD) genes were studied in a series of 314 Finns from northern Finland and in a material of 4,348 conscripts and blood donors from the counties of Norrbotten and Västerbotten in northern Sweden. The Swedish individuals were distributed into 23 subpopulations according to place of birth. The frequency of the PGDC gene was comparatively high in Finns (5.3%) and showed significant variations between subpopulations (from 5.3 to 0.0%). The frequency of the PGDC gene showed a cline, with a decreasing gene frequency in the north-south direction. This geographical pattern could be explained in terms of Lappish and Finnish influence.
authors.affiliation: Department of Medical Genetics, University of Umeå, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Beckman
authors.forename: G
authors.initials: G
authors.lastname: Beckman
authors.forename: P O
authors.initials: PO
authors.lastname: Nylander
mesh_terms: D005787:Gene Frequency; D006801:Humans; D010641:Phenotype; D010734:Phosphogluconate Dehydrogenase / Q000235:genetics*; D011110:Polymorphism, Genetic; D013548:Sweden
chemical_list: D010734:Phosphogluconate Dehydrogenase