title: Serial analysis of fibronectin concentration in sera from septic patients.
abstract: Serum fibronectin (Fn) level was serially determined in nineteen septic patients. Fn concentration was found significantly decreased in septic patients (mean +/- SE, 120 +/- 11 micrograms/ml) as compared to the control (205 +/- 11 micrograms/ml). The decrease of Fn was correlated with the severity of sepsis; it was persistent and more important in severe septic cases. The lowest Fn concentration was found in nonsurviving patients (78 +/- 18 micrograms/ml). Serum Fn level may reflect the degree of organ failure and predict the evolution of sepsis.
authors.affiliation: Department of Immunology, V. Babes Institute, Bucharest, Romania.
authors.forename: R
authors.initials: R
authors.lastname: Bălună
authors.forename: R
authors.initials: R
authors.lastname: Tarnavschi
authors.forename: D
authors.initials: D
authors.lastname: Barac
authors.forename: I
authors.initials: I
authors.lastname: Belascu
authors.forename: H
authors.initials: H
authors.lastname: Georgescu
mesh_terms: D000328:Adult; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006386:Hemagglutination Tests; D006801:Humans; D018805:Sepsis / Q000097:blood*; D014591:Uterine Diseases / Q000097:blood
chemical_list: D005353:Fibronectins