[The correlation between the reduction rate of tumor and the survival time of patients as an effect of chemotherapy].
The correlation between reduction rate of tumor by anti-cancer chemotherapy and survival time of patients was studied in 17 cases with liver metastases from 12 stomach cancers and 5 colonic cancers. The survival time ranged from 4 to 15 months (mean 8.4 +/- 4.3 months) in 5 cases with CR or PR, from 6 to 15 months (mean 9.8 +/- 4.1 months) in 4 cases with NC, from 2 to 12 months (mean 8.0 +/- 3.7 months) in 8 cases with PD. There was no correlation between reduction rate of tumor and survival time of patients. The tumor marker doubling times, both before and after chemotherapy, were studied in 5 cases. The difference of doubling time between before and after chemotherapy was not significant. These results suggest that individual doubling time plays an important role in survival time as an effect of chemotherapy.
Takahashi
Y
Y
Department of Surgery, Kanazawa University, Japan.
Kusama
S
S
Mai
M
M
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D013997:Time Factors
D014408:Biomarkers, Tumor