Differential protection of radiation-induced DNA single-strand breaks and cell survival by solcoseryl.
V79 Chinese hamster cells were studied in vitro for modification of cobalt-60 gamma radiation effects by solcoseryl. This treatment did not modify cell survival but did protect against DNA single-strand breaks.
Sigdestad
C P
CP
Radiation Oncology Department, J. Graham Brown Cancer Center, University of Louisville, Kentucky 40202.
Doak
K W
KW
Grdina
D J
DJ
D000183:Actihaemyl / Q000494:pharmacology*; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D006224:Cricetinae; D004247:DNA / Q000528:radiation effects*; D004249:DNA Damage; D005720:Gamma Rays; D066298:In Vitro Techniques; D011837:Radiation-Protective Agents; D014020:Tissue Extracts / Q000494:pharmacology*
D011837:Radiation-Protective Agents; D014020:Tissue Extracts; D000183:Actihaemyl; D004247:DNA