title: Progressive activation of paratrigeminal nucleus during entrance to hibernation.
abstract: The paratrigeminal nucleus (Pa5) undergoes a progressive increase in its uptake of 2-[14C]deoxyglucose (2DG) relative to other brain structures during entrance to hibernation in the ground squirrel. This highly significant increase results in the Pa5 becoming the most highly labeled brain region during hibernation, even though it exhibits one of the lowest levels of 2DG uptake in the brain during the nonhibernating state. The progressive activation of the Pa5 observed during entrance is reversed during arousal from hibernation. These observations and the neuroanatomical projections of the Pa5 implicate this nucleus as playing a role in the entrance and maintenance of the hibernating state.
authors.affiliation: Department of Biological Sciences, Stanford University, California 94305.
authors.forename: T S
authors.initials: TS
authors.lastname: Kilduff
authors.forename: F R
authors.initials: FR
authors.lastname: Sharp
authors.forename: H C
authors.initials: HC
authors.lastname: Heller
mesh_terms: D000818:Animals; D001345:Autoradiography; D001933:Brain Stem / Q000502:physiology*; D003847:Deoxyglucose / Q000378:metabolism; D006605:Hibernation; D012016:Reference Values; D012589:Sciuridae / Q000502:physiology*
chemical_list: D003847:Deoxyglucose