title: Nucleotide sequence of the human theta 1-globin gene.
abstract: We have cloned and sequenced the human theta 1-globin gene. The nucleotide sequence and organization of the human theta 1 gene (exons, introns, promoter, and polyadenylation signals) are similar to those reported for the orangutan theta 1-globin gene. If these genes are functional, the sequences of their theta 1-globin chains would differ by only one amino acid residue (at position 137).
authors.affiliation: Department of Cell and Molecular Biology, Medical College of Georgia, Augusta 30912-3331.
authors.forename: J M
authors.initials: JM
authors.lastname: Gonzalez-Redondo
authors.forename: I S
authors.initials: IS
authors.lastname: Han
authors.forename: Y C
authors.initials: YC
authors.lastname: Gu
authors.forename: T H
authors.initials: TH
authors.lastname: Huisman
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D005260:Female; D005796:Genes; D005914:Globins / Q000235:genetics*; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization
chemical_list: D005914:Globins