New orally active alpha-ketohydroxy pyridine chelators for the treatment of iron overload.
Kontoghiorghes
G J
GJ
Department of Haematology, Royal Free Hospital Medical School, London, England.
D000284:Administration, Oral; D000818:Animals; D003855:Deoxyribose / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D005293:Ferritins / Q000378:metabolism; D007501:Iron / Q000378:metabolism*; D007502:Iron Chelating Agents / Q000008:administration & dosage / Q000494:pharmacology*; D007781:Lactoferrin; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011817:Rabbits; D014168:Transferrin / Q000378:metabolism
D007502:Iron Chelating Agents; D014168:Transferrin; D003855:Deoxyribose; D005293:Ferritins; D007501:Iron; D007781:Lactoferrin