title: Is there a role for simple hysterectomy after irradiation for bulky cervical carcinoma?
abstract: Twenty eight patients with bulky cervical carcinoma, who were treated by irradiation and simple hysterectomy, were studied. Eight of these patients had non-radical pre-operative irradiation. The patients had various FIGO-stages. The prognostic significance of morphologically intact tumor cells in the hysterectomy specimen and the relationship between pre-operative irradiation dosage, intact tumor cells and recurrences is discussed. Positive pelvic lymph-nodes obtained by sampling had more prognostic significance than intact tumor cells in the hysterectomy specimen. The role of adjunctive hysterectomy in local tumor control was not evident. Non-radical pre-operative irradiation proved to be inadequate.
authors.affiliation: Dept. of Obstetrics and Gynaecology, University Hospital Groningen, Netherlands.
authors.forename: D J
authors.initials: DJ
authors.lastname: Tinga
authors.forename: J
authors.initials: J
authors.lastname: Bouma
authors.forename: H
authors.initials: H
authors.lastname: Hollema
authors.forename: J W
authors.initials: JW
authors.lastname: Oosterhuis
authors.forename: P R
authors.initials: PR
authors.lastname: Timmer
authors.forename: J G
authors.initials: JG
authors.lastname: Aalders
mesh_terms: D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*