title: Changes in anal sphincter tone at induction of anaesthesia.
abstract: Changes in anal pressure have been monitored during the induction of anaesthesia. Falls in pressure accompany loss of consciousness following bolus doses of commonly used intravenous and inhalational anaesthetic agents. Subsequent rises in pressure towards pre-anaesthetic levels are usually associated with the time taken to correct responses and initial recovery. Premedication, including anticholinergic drugs in conventional dosage, does not affect anal pressure.
authors.affiliation: Department of Anaesthesia, University Hospital, Nottingham.
authors.forename: M J
authors.initials: MJ
authors.lastname: Harrison
authors.forename: P A
authors.initials: PA
authors.lastname: Tomlinson
authors.forename: C S
authors.initials: CS
authors.lastname: Ubhi
authors.forename: J
authors.initials: J
authors.lastname: Wright
authors.forename: J D
authors.initials: JD
authors.lastname: Hardcastle
mesh_terms: D000530:Alfaxalone Alfadolone Mixture; D001003:Anal Canal / Q000502:physiology*; D000768:Anesthesia, General; D001341:Autonomic Nervous System / Q000187:drug effects; D005045:Etomidate; D006221:Halothane; D006801:Humans; D008723:Methohexital; D009129:Muscle Tonus / Q000187:drug effects*; D009609:Nitrous Oxide; D011229:Preanesthetic Medication; D011312:Pressure; D011897:Random Allocation
chemical_list: D000530:Alfaxalone Alfadolone Mixture; D008723:Methohexital; D009609:Nitrous Oxide; D006221:Halothane; D005045:Etomidate