[Diagnosis of ocular toxoplasmosis by the ELISA method applied to the determination of immunoglobulins of the aqueous humor].
The toxoplasmosic origin of focal chorioretinitis can be detected on the basis of certain clinical signs in the fundus. However, this must be biologically confirmed by studying the local production of specific antibodies. For that purpose, the rate of intraocular specific Immunoglobulins is compared to the serum rate. The ELISA method is well adapted to quantitative determination of microamounts in aqueous humors. The authors report a study of 103 patients of whom, 28 were suffering from uveitis, and have studied the correlation between clinical lesions and results of the ELISA test. There was no false positive in the first group reference series, and in the positive cases there was a very high correlation with the clinical indicators.
Payeur
G
G
Service d'ophtalmologie, Centre Hospitalier de Mulhouse.
Bijon
J C
JC
Pagano
N
N
Kien
T
T
Candolfi
E
E
Penner
M F
MF
D000293:Adolescent; D000328:Adult; D000368:Aged; D000913:Antibodies, Protozoan / Q000032:analysis*; D001082:Aqueous Humor / Q000276:immunology*; D002648:Child; D002825:Chorioretinitis / Q000209:etiology; D003951:Diagnostic Errors; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis* / Q000276:immunology; D014605:Uveitis / Q000209:etiology
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007136:Immunoglobulins
Diagnostic de la toxoplasmose occulaire par la méthode ELISA appliquée au dosage des immunoglobulines de l'humeur aqueuse.