[The aggressiveness of prostatic cancer in relation to classification and grading].
On 231 autoptical examined prostatic carcinomas it was checked retrospectively if a correlation between the metastasizing behaviour and the histological tumor type is present. 145 (63%) of the examined cases have been metastasized, of that 106 (73%) in multiple organs and 39 (27%) in one organ: 18 times in the skeleton (12.4%), 13 times in lymph nodes (8.9%), six times in the liver (4.1%) and twice in the lung (1.4%). Lymph node metastases were preferably found in the pelvic (69%) and paraaortal nodes (78%), at which in 30% of the cases the regional groups have been jumped across. The metastasizing behaviour was dependent on the histological type and the age of the patient. To an assessment of the prognosis the only differentiation of the uniform and the pluriform cancer type is insufficiently. The examination of a histological grading, which was proposed by the Patho-Urological circle "prostatic cancer" of the FRG, in 104 unselected cases on the other hand has shown not only an increasing metastasizing tendency, but also an increasing metastasizing thickness and variety with growing malignancy grade. This grading represents well the tumor aggressiveness, is simple reproducible and should be appreciate to a wide use by pathologists.
Mehlhorn
J
J
Pathologisches Institut, Medizinischen Versorgungsbereich Karl-Marx-Stadt/Stollberg.
D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology*
Die Aggressivität des Prostatakarzinoms in Abhängigkeit von Klassifikation und Grading.