title: Measuring human IgG4 by a two-site immunoradiometric assay with monoclonal antibodies.
abstract: By using 2 monoclonal antibodies, we developed a solid-phase 2-site immunoradiometric assay for measuring human IgG4. The measuring range (0.05-20 micrograms/ml) covered more than 2 orders of magnitude. The sensitivity level should make this assay especially useful when IgG4 concentrations are too low to be detected by conventional methods.
authors.affiliation: Department of Pediatrics, Loma Linda University, Calif.
authors.forename: R H
authors.initials: RH
authors.lastname: Bui
authors.forename: G A
authors.initials: GA
authors.lastname: Molinaro
authors.forename: W C
authors.initials: WC
authors.lastname: Eby
authors.forename: R
authors.initials: R
authors.lastname: Jauhar
authors.forename: J W
authors.initials: JW
authors.lastname: Mace
mesh_terms: D000911:Antibodies, Monoclonal; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007223:Infant; D007231:Infant, Newborn; D007457:Iodine Radioisotopes; D011863:Radioimmunoassay / Q000379:methods
chemical_list: D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D007457:Iodine Radioisotopes