Inhalation toxicity of methyl difluoromalonyl fluoride in rats.
Methyl 2,2-difluoromalonyl fluoride (MMF) is highly toxic by inhalation producing mortality in rats exposed for 4 hours to 0.55 mg/L. Repeated inhalation exposures of rats to 0.009 mg/L produced irritation but no other signs of a toxic response. Mortality was encountered following repeated exposures to 0.066 mg/L.
Kennedy
G L
GL
Central Research and Development Department, E. I. du Pont de Nemours and Company, Haskell Laboratory for Toxicology and Industrial Medicine, Newark, Delaware 19714.
Burgess
B A
BA
Chen
H C
HC
D000280:Administration, Inhalation; D000393:Air Pollutants / Q000633:toxicity*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D008297:Male; D008314:Malonates / Q000008:administration & dosage / Q000032:analysis / Q000633:toxicity*; D009929:Organ Size / Q000187:drug effects; D051381:Rats
D000393:Air Pollutants; D008314:Malonates; C056889:methyl 2,2-difluromalonyl fluoride