title: Cancer mortality trends in Canada: breast cancer, 1925-1982.
abstract: Breast cancer is the number one cause of death in Canadian women aged 20-74 years (for all 5-year age groups) and the second leading cause for those aged 75 years and over. To assess the long-term mortality of this disease, we collected and analyzed data from 1925 to 1982. A 3-year base period was used to obtain person-years exposure using Newton-Cotes' method. All rates were standardized to the 1956 Canadian population for age and sex using the direct method. Standard errors of age-standardized death rates (ASDR) were computed using Chiang's method. Mortality from breast cancer has been quite stable during the study period (at about 23.7 deaths/100,000 population). The lowest ASDR occurred in 1926 (at 17.5 deaths/100,000 population); the highest occurred in 1946 (when it reached 26.6 deaths/100,000 population). During 1951-1981, the ASDR fluctuated between 22.8 and 24.0 deaths/100,000 population. Examination of age sex-specific rates revealed a steady trend for 25-44-year-old females and a rise in mortality in the older age groups. It is suggested that part of this rise may be associated with changes in environment, life-style, and therapy.
authors.affiliation: Department of Preventive Medicine and Biostatistics, Faculty of Medicine, University of Toronto, Ontario, Canada.
authors.forename: D V
authors.initials: DV
authors.lastname: Vakil
authors.forename: A
authors.initials: A
authors.lastname: Ayiomamitis
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000401:mortality*; D002170:Canada; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012042:Registries; D012737:Sex Factors