[Ultrasonic coagulometry as a method of testing compounds with antiplasmin activity].
An ultrasonic interferometer has been used to study the process of fibrin clot lysis according to the decrease in the rate of propagation of an ultrasonic wave in the latter. A significant decrease in the sound fall rate on adding epsilon-aminocaproic and trans-4-aminomethylcyclohexanecarbonic acids to the system indicates their activity inhibiting fibrinolysis. N-nicotinoyl derivatives of this compounds possess less pronounced antiplasmin activity.
Zabelin
N N
NN
Gribauskas
P S
PS
Moĭseenok
A G
AG
D000933:Antifibrinolytic Agents / Q000494:pharmacology*; D001777:Blood Coagulation / Q000187:drug effects*; D001780:Blood Coagulation Tests; D006801:Humans; D014465:Ultrasonics
D000933:Antifibrinolytic Agents
Ul'trazvukovaia koagulometriia kak sposob testirovaniia soedineniĭ s antiplazminovoĭ aktivnost'iu.