Dipole-tracing of 'awareness' attenuating the cortical components of somatosensory evoked potentials.
Using the dipole-tracing method, the source generators of N18, P22 and P40 of the somatosensory evoked potential (SEP) were estimated as the equivalent dipole. After voluntary action of the thumb flexion, no changes were observed in N18 or P40, but the amplitude of P22 was suppressed. The after-effects of intention accompanied by a voluntary action or the subject's awareness that electrical stimulation will be given after the voluntary action were treated as 'awareness'. By subtracting the pure SEP from SEP during 'awareness', it was found that the equivalent dipole of 'awareness' of P22 was located at the same region of pure P22, but the vector was of opposite orientation. 'Awareness' attenuated the perceptive potential of SEP like P22 generated in the cortex.
Homma
S
S
Department of Physiology, School of Medicine, Chiba University, Japan.
Nakajima
Y
Y
Musha
T
T
He
B
B
Okamoto
Y
Y
D001364:Awareness / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D004558:Electric Stimulation; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D005073:Evoked Potentials, Somatosensory; D006801:Humans; D008475:Median Nerve / Q000502:physiology; D009068:Movement; D013003:Somatosensory Cortex / Q000502:physiology*