[Nicotine and the gastrointestinal tract].
Reflux esophagitis occurs much more often in smokers because of reduction of saliva production and lessened tonus of the LES (lower esophageal sphincter). Duodenal ulcers heal during H2-blocking agents in smokers slower than during placebo-therapy in non smokers. Mortality of duodenal ulcer in smokers is 2 to 7 times increased.
Clodi
P H
PH
Internen Abteilung, Krankenhauses der Barmherzigen, Brüder, Linz.
D004381:Duodenal Ulcer / Q000209:etiology; D004942:Esophagitis, Peptic / Q000209:etiology; D005767:Gastrointestinal Diseases / Q000209:etiology*; D006801:Humans; D009538:Nicotine / Q000009:adverse effects*; D012907:Smoking / Q000009:adverse effects*
D009538:Nicotine
Nikotin und Gastrointestinaltrakt.