title: Biomechanics of fascia lata ligament replacements: early postoperative changes in the goat.
abstract: Mechanical properties of fascia lata autografts used to replace the anterior cruciate ligament (ACL) in the goat were measured at 0, 2, 4, and 8 weeks after surgery. The ACL was replaced in the right knee of 50 animals divided equally into two groups according to graft fixation technique: (a) two smooth staples at each end, with the tissue pulled back toward the joint over the first staple and (b) reinforced fixation with a spiked bushing placed through the tissue and a 3-cm-long flat polypropylene braid sutured to each end of the graft. Eleven unoperated contralateral knees were tested as controls. All statistically significant effects of the reinforced versus staple fixation were observed at 0 weeks, with the reinforced group showing less anteroposterior (AP) translation of the joint and greater maximum force and stiffness of the femur-graft-tibia units. The reinforced group had increased AP translation and decreased strength and stiffness by 2 weeks after surgery. Increased AP translation resulted primarily from increases in the low-stiffness region of the force-displacement curve (primary AP translation) and to a lesser extent from increased translation in the high-stiffness region (secondary anterior translation). Failures at 0 weeks with the reinforced fixation occurred at the bushing or end of the reinforcing braid, while all but one of the later failures occurred in the tissue mid-substance. In the staple group, maximum force was greater at 8 weeks than at 0 weeks, as the failure locations changed from the fixation to the tissue mid-substance.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Biomechanics Laboratories, University of Cincinnati, OH 45221-0048.
authors.forename: J P
authors.initials: JP
authors.lastname: Holden
authors.forename: E S
authors.initials: ES
authors.lastname: Grood
authors.forename: D L
authors.initials: DL
authors.lastname: Butler
authors.forename: F R
authors.initials: FR
authors.lastname: Noyes
authors.forename: H V
authors.initials: HV
authors.lastname: Mendenhall
authors.forename: C L
authors.initials: CL
authors.lastname: Van Kampen
authors.forename: R L
authors.initials: RL
authors.lastname: Neidich
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D005205:Fascia / Q000637:transplantation*; D005206:Fascia Lata / Q000637:transplantation*; D005260:Female; D005269:Femur / Q000601:surgery; D006041:Goats; D007593:Joint Instability / Q000503:physiopathology; D007719:Knee Joint / Q000502:physiology / Q000503:physiopathology / Q000601:surgery*; D008023:Ligaments, Articular / Q000601:surgery*; D008297:Male; D008722:Methods; D008954:Models, Biological; D011126:Polypropylenes; D011183:Postoperative Complications; D011184:Postoperative Period; D013528:Surgical Staplers; D013718:Tensile Strength; D013977:Tibia / Q000601:surgery; D013997:Time Factors
chemical_list: D011126:Polypropylenes