title: Effect of lectins on KK-47 bladder cancer cell line.
abstract: The effect of three lectins, Ricinus communis agglutinin (RCA II), concanavalin agglutinin (ConA), and wheat germ agglutinin (WGA), on KK-47 bladder cancer cell line was studied, RCA II showed effective inhibition of H3-uridine and H3-thymidine uptake by KK-47. ConA showed a stimulatory effect in all three concentrations used. WGA also showed stimulatory effect, but it was less pronounced than ConA.
authors.affiliation: Department of Urology, University of Mainz Medical School, F. R. Germany.
authors.forename: M A
authors.initials: MA
authors.lastname: Bazeed
authors.forename: E
authors.initials: E
authors.lastname: Becht
authors.forename: T
authors.initials: T
authors.lastname: Schärfe
authors.forename: J
authors.initials: J
authors.lastname: Schmidt
authors.forename: G H
authors.initials: GH
authors.lastname: Jacobi
authors.forename: J W
authors.initials: JW
authors.lastname: Thüroff
mesh_terms: D002277:Carcinoma / Q000378:metabolism; D002367:Ricinus communis; D003208:Concanavalin A / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D037102:Lectins / Q000493:pharmacokinetics / Q000494:pharmacology*; D037121:Plant Lectins; D010947:Plants, Toxic; D013936:Thymidine / Q000378:metabolism; D014407:Tumor Cells, Cultured; D014529:Uridine / Q000378:metabolism; D001749:Urinary Bladder Neoplasms / Q000378:metabolism; D014909:Wheat Germ Agglutinins / Q000494:pharmacology
chemical_list: D037102:Lectins; D037121:Plant Lectins; C017707:Ricinus communis agglutinin-1; D014909:Wheat Germ Agglutinins; D003208:Concanavalin A; D013936:Thymidine; D014529:Uridine