title: Computer simulation of fluid resuscitation in trauma. I. Description of an extensive pathophysiological model and its first validation.
abstract: Computer-based 'patient simulators' are of a potential value in diagnosis, monitoring and therapy of the severely ill patient with trauma. An extensive pathophysiological model is described and documented in full detail. The model makes it possible to calculate and predict clinically important state variables on the basis of fluid input and fluid losses. Sample runs are presented for illustrations in hemorrhage, fluid and salt loading.
authors.affiliation: Burn Center, University Hospital, Uppsala, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Hedlund
authors.forename: B
authors.initials: B
authors.lastname: Zaar
authors.forename: T
authors.initials: T
authors.lastname: Groth
authors.forename: G
authors.initials: G
authors.lastname: Arturson
mesh_terms: D000818:Animals; D003198:Computer Simulation; D005440:Fluid Therapy; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008432:Mathematical Computing; D008954:Models, Biological; D012774:Shock, Traumatic / Q000503:physiopathology* / Q000628:therapy; D012984:Software; D013552:Swine