[Hemorheological/hemodynamic study on miniaturized capillary filters in the concept of an implantable artificial kidney].
The conception of an implantable kidney provides the substitute of the non-functioning kidney by a technical-biological system. The filtration function is to be performed by a capillary hemofilter. The results obtained in an open test circulation on 3 filters produced by optimum aspects were represented and compared with the physiological performance parameters of the kidney. The special importance of the construction of the flow conditions in the single capillary is accentuated as the fundamental aspect for additional optimization. An optimized capillary filter produced the necessary filtration rate for maintaining the homeostasis on condition of a low-protein diet and an increased level of blood urea. The changes of the hemorheologic parameters is to come up by an adequate absorption of fluid in the colon.
Dörp
E
E
Abt. für Pathophysiologie, Wilhelm-Pieck-Universität Rostock.
Wüstenberg
P W
PW
Schumann
L
L
Schröder
J
J
Trekel
S
S
Falkenhagen
D
D
Klinkmann
H
H
Preussner
S
S
Putzke
H P
HP
Röver
K H
KH
D002196:Capillaries / Q000502:physiology* / Q000648:ultrastructure; D006440:Hemofiltration; D006706:Homeostasis; D006801:Humans; D007668:Kidney / Q000502:physiology; D007688:Kidneys, Artificial; D008854:Microscopy, Electron; D019736:Prostheses and Implants; D012079:Renal Circulation; D012212:Rheology; D014508:Urea / Q000097:blood
D014508:Urea
Hämorheologische/hämodynamische Untersuchungen an miniaturisierten Kapillarfiltern im Entwicklungskonzept für eine implantierbare künstliche Niere.