Regional assignment of human tissue factor gene (F3) to chromosome 1p21-p22.
Tissue factor, or coagulation factor III, is a membrane-bound glycoprotein and acts as a cofactor for factor VII-dependent initiation of blood coagulation. The tissue factor gene (F3) was previously assigned to human chromosome 1, region p21-pter. The present report has further refined the mapping position to 1p21-p22 using a cDNA probe for the tissue factor gene and in situ hybridization to metaphase chromosomes.
Kao
F T
FT
Eleanor Roosevelt Institute for Cancer Research, Denver, Colorado 80206.
Hartz
J
J
Horton
R
R
Nemerson
Y
Y
Carson
S D
SD
D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D006801:Humans; D009693:Nucleic Acid Hybridization; D013925:Thromboplastin / Q000235:genetics*
D013925:Thromboplastin