[The biotransformation of fenetylline].
After oral administration of 3,7-dihydro-1,3-dimethyl-7-2 [(1-methyl-2-phenylethyl)-amino-ethyl]-1H-purine-2,6-dione (fenetylline, Captagon), 7 new metabolites could be detected in urine besides 4 known substances. The metabolites were identified by gas chromatography (GC) and by comparison of the mass spectra (MS) of metabolites with those of authentic reference compounds using a combined GC/MS method.
Rücker
G
G
Pharmazeutischen Institut, Universität Bonn.
Neugebauer
M
M
Heiden
P G
PG
D000328:Adult; D000662:Amphetamines / Q000493:pharmacokinetics* / Q000652:urine; D001711:Biotransformation; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008875:Middle Aged; D013806:Theophylline / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000652:urine
D000662:Amphetamines; D013806:Theophylline; C004518:fenethylline
Untersuchungen zur Biotransformation von Fenetyllin.