title: [Evaluation of genetic consequences of 238Pu incorporation into mammals].
abstract: The genetic effects of gonadal burdens of 238Pu after single injection were studied in male mice. The activity of plutonium was 7 to 1850 Bk/g. The average doses of accumulated alpha-particles in testis varied from 2 to 96 Gy.10(-2), the dose rate being 0.004 to 1 Gy.10(-2) per day. The genetic end points are: the dominant lethal mutation rate; the frequency of reciprocal translocations; the recessive lethal mutation rate and frequency of abnormal sperm head morphology. For all tests used, no linear dependence of the effect on the alpha-dose was observed. The RBE value of alpha-irradiation was 10-20 relative to chronic gamma-irradiation.
authors.forename: M D
authors.initials: MD
authors.lastname: Pomerantseva
authors.forename: L K
authors.initials: LK
authors.lastname: Ramaĭia
authors.forename: V A
authors.initials: VA
authors.lastname: Shevchenko
authors.forename: G A
authors.initials: GA
authors.lastname: Vilkina
authors.forename: A M
authors.initials: AM
authors.lastname: Liaginskaia
mesh_terms: D000512:Alpha Particles; D000818:Animals; D001822:Body Burden; D005260:Female; D005720:Gamma Rays; D005804:Genes, Lethal / Q000528:radiation effects; D008297:Male; D051379:Mice; D009154:Mutation; D011005:Plutonium / Q000633:toxicity*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000235:genetics; D012062:Relative Biological Effectiveness
chemical_list: D011005:Plutonium
vernacular_title: Otsenka geneticheskikh posledstviĭ postupleniia 238Pu v organizm mlekopitaiushchikh.