title: Phosphate-dependent glutaminase in the human term placental mitochondria.
abstract: The properties of placental glutaminase described in this paper, namely relatively high substrate affinity. Hill coefficient about 1.6, inhibition by glutamate, and the lack of activation by bicarbonate make the placental enzyme very similar to the "kidney type" glutaminase isoenzyme of rat tissues.
authors.affiliation: Department of Biochemistry, Academic Medical School, Gdańsk, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Makarewicz
authors.forename: J
authors.initials: J
authors.lastname: Swierczynski
mesh_terms: D000818:Animals; D005260:Female; D005972:Glutaminase / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D008928:Mitochondria / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000201:enzymology; D008931:Mitochondria, Muscle / Q000201:enzymology; D010710:Phosphates / Q000494:pharmacology*; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D051381:Rats
chemical_list: D007527:Isoenzymes; D010710:Phosphates; D005972:Glutaminase