title: The incidence of bacteremia in skin surgery of the head and neck.
abstract: The normal microflora of skin vary significantly between sebaceous rich, wet, and dry areas. This would be expected to influence the likelihood of developing transient bacteremia while undergoing skin surgery on these different areas, thereby affecting the risk of infective endocarditis from such procedures. We evaluated the incidence of transient bacteremia in 45 patients undergoing skin surgery on the sebaceous rich areas of the head and neck. After surveillance skin cultures, aerobic and anaerobic blood culture samples were taken at 0, 1, 5, and 15 minutes after the start of the procedure. All baseline blood culture results were negative. Three of the 45 patients developed transient bacteremia within the first 15 minutes after the start of the procedures. Samples from two patients grew pure cultures of Propionibacterium acnes and that from one patient grew a pure culture of Staphylococcus hominis, yielding a 7% incidence of bacteremia in the 45 patients studied. These data support the use of perioperative prophylactic antibiotics for surgery involving clinically uninfected skin of the head and neck only in patients with prosthetic heart valves. This is in keeping with the current recommendations of the American Heart Association against the need for antibiotic prophylaxis for nonprosthetic valve endocarditis in patients undergoing cutaneous surgery on clinically uninfected skin.
authors.affiliation: Department of Dermatology, Hospital of the University of Pennsylvania, Philadelphia 19104.
authors.forename: A C
authors.initials: AC
authors.lastname: Halpern
authors.forename: J J
authors.initials: JJ
authors.lastname: Leyden
authors.forename: L M
authors.initials: LM
authors.lastname: Dzubow
authors.forename: K J
authors.initials: KJ
authors.lastname: McGinley
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D062109:Dermatologic Surgical Procedures; D005260:Female; D006197:Hair / Q000637:transplantation; D006257:Head; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck; D011183:Postoperative Complications / Q000453:epidemiology* / Q000382:microbiology; D011300:Preoperative Care; D018805:Sepsis / Q000453:epidemiology* / Q000382:microbiology; D012867:Skin / Q000382:microbiology; D012878:Skin Neoplasms / Q000601:surgery
chemical_list: D000891:Anti-Infective Agents, Local