[Pathogens in neonatal infection and their resistance properties].
Among 1252 consecutively treated intensive-neonatologic patients during the years 1985 to 1987 79 cases (= 6.5%) of neonatal septicemia were diagnosed by positive blood- and/or cerebrospinal fluid cultures. The relation between early onset type (up to the 4th day of life) and late onset type was 4:1. The most frequent pathogen was Staphylococcus epidermidis (40% of early onset type, 56% of late onset type) followed in the case of early onset type by Listeria monocytogenes (13%), Streptococci (11%), E. coli (11%) and Staphylococcus aureus (10%). Susceptibility to antibiotics is described. Primary therapy of early onset type septicemia must be effective against Listeria monocytogenes and Streptococci. We recommend a combination of a beta-lactam- and an aminoglycosid antibiotic. In case of late onset type we used a cephalosporin in combination with netilmycin. The importance of good hospital hygiene, frequent blood cultures and correct application of aminoglycosid antibiotics is pointed out.
Tulzer
G
G
Neugeborenen- und Säuglingsabteilung, Landeskinder-krankenhauses Linz.
Hohenauer
L
L
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D004352:Drug Resistance, Microbial; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy*; D007363:Intensive Care Units, Neonatal; D018805:Sepsis / Q000188:drug therapy*
D000900:Anti-Bacterial Agents
Erreger der Neugeborenensepsis und ihr Resistenzverhalten.