title: Acanthamoeba keratitis, clinico-pathological report of 2 cases.
abstract: Acanthamoebae have in the last 14 years been reported to be responsible for severe keratitis in an increasing number of cases. To our knowledge this is the first report of acanthamoeba keratitis (AK) in Scandinavia. Two young males, both wearing soft contact lenses for extended wear, developed long lasting, therapy resistant keratitis. As the keratitis progressed to risk of perforation, keratoplasty was performed on the clinical, and in the one case biopsy-proven diagnosis of AK. Histopathology on the removed discs demonstrated the presence of typical acanthamoebae in the corneal stroma. The observation period after keratoplasty is at present 5 and 20 months, respectively. Both grafts have remained clear and visual acuity is 6/9-6/12 with glasses.
authors.affiliation: University Eye Clinic, Rigshospitalet, Copenhagen, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Brincker
authors.forename: E
authors.initials: E
authors.lastname: Gregersen
authors.forename: J U
authors.initials: JU
authors.lastname: Prause
mesh_terms: D000048:Acanthamoeba / Q000302:isolation & purification; D000293:Adolescent; D000328:Adult; D000562:Amebiasis / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D000818:Animals; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects; D006801:Humans; D007634:Keratitis / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D008297:Male; D013548:Sweden