[Congenital intrinsic factor deficiency. Apropos of 3 cases in a sibship].
Three familial cases of congenital intrinsic factor deficiency are reported: the stress is put on the interest of gastric investigations and especially of the quantity of intrinsic factor in the gastric juice when investigating megaloblastic anemia due to vitamin B12 deficiency. The study of the level of intrinsic factor in the gastric juice is proposed as a test for identifying carriers.
Loras-Duclaux
I
I
Service d'Hépato-Gastro-Entérologie Infantile, Hôpital E.-Herriot, Lyon.
Descos
B
B
Souillet
G
G
Lachaux
A
A
Badinand
P
P
Montagnon
N
N
Minaire
Y
Y
Hermier
M
M
D000748:Anemia, Macrocytic / Q000151:congenital*; D000749:Anemia, Megaloblastic / Q000151:congenital* / Q000235:genetics; D002675:Child, Preschool; D005260:Female; D005750:Gastric Juice / Q000032:analysis; D006580:Genetic Carrier Screening; D006801:Humans; D007223:Infant; D007437:Intrinsic Factor / Q000172:deficiency*; D014806:Vitamin B 12 Deficiency / Q000151:congenital
D007437:Intrinsic Factor
Déficit congénital en facteur intrinsèque. A propos de 3 cas dans une fratrie.