title: Lipid composition of miniature pig platelets.
abstract: 1. Analyses of platelet lipid composition were carried out on material pooled from male and female miniature pigs. 2. The cholesterol/phospholipid molar ratio was 0.6. 3. Phosphatidylcholine represents the major class of phospholipids (47%) and phosphatidylinositol the minor (2%). 4. The main fatty acids of phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol and sphingomyelin were: palmitic, stearic, oleic, linoleic and arachidonic acids. 5. The ratios of saturated to unsaturated fatty acids were: sphingomyelin, 1.7; phosphatidylcholine, 1.2; phosphatidylserine, 0.9; phosphatidylethanolamine and phosphatidylinositol, 0.6. 6. Our results suggests that human and miniature pig platelet lipids bear several characteristics in common. This fact would allow miniature pig to be used as a new experimental model.
authors.affiliation: Medicina Y Cirugia Experimental, Hospital General Gregorio Marañon, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Mata
authors.forename: P
authors.initials: P
authors.lastname: Garcia-Barreno
authors.forename: A M
authors.initials: AM
authors.lastname: Municio
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000032:analysis*; D002784:Cholesterol / Q000097:blood / Q000302:isolation & purification; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D010743:Phospholipids / Q000097:blood* / Q000302:isolation & purification; D013045:Species Specificity; D013552:Swine / Q000097:blood; D013556:Swine, Miniature / Q000097:blood*
chemical_list: D005227:Fatty Acids; D010743:Phospholipids; D002784:Cholesterol