title: Bone mineral content in normal UK subjects.
abstract: Bone mineral content in the lumbar vertebrae and in the shaft of the left radius has been measured in 129 normal British subjects using quantitative computed tomography and single-photon absorptiometry. Significant negative correlations between bone mineral content and age were found at both sites in males and females (p less than 0.001 in all cases). When expressed in g/cm the bone mineral content in the radial shaft showed significant positive correlations with body height and weight in both sexes, but after correction for bone size only a weak correlation with body height in males was found. Spinal trabecular bone mineral content showed no significant correlations with body height or weight in either sex. Comparison of the values obtained with normal data from centres in the USA revealed lower mean values for both radial and spinal bone mineral content in the British subjects. These differences emphasize the importance of using locally derived normal data for comparison with values obtained from patients.
authors.affiliation: Department of Pathology, University of Wales Hospital and College of Medicine, Cardiff.
authors.forename: J E
authors.initials: JE
authors.lastname: Compston
authors.forename: W D
authors.initials: WD
authors.lastname: Evans
authors.forename: E O
authors.initials: EO
authors.lastname: Crawley
authors.forename: C
authors.initials: C
authors.lastname: Evans
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001827:Body Height; D001835:Body Weight; D001842:Bone and Bones / Q000032:analysis* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000032:analysis*; D011877:Radionuclide Imaging; D011884:Radius / Q000000981:diagnostic imaging; D012016:Reference Values; D012737:Sex Factors; D013131:Spine / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D006113:United Kingdom
chemical_list: D008903:Minerals