[Correction (in vitro) of proteinase inhibitor balance in the blood of patients after cardiosurgical interventions].
Proteinase-inhibitor balance in human plasma before and after artificial blood circulation was examined. It was shown that trypsinlike and chemotrypsinlike proteinases activities after this procedure were 1.6 and 2.8 times higher and antitryptic activity 1.2 times lower than in the same patients before the procedure. The 40-50% decrease of proteinase activity in human plasma after artificial blood circulation was observed as a result of in vitro plasmasorption on immobilized human urinary trypsin inhibitor.
Ogloblina
O G
OG
Bazhenova
G E
GE
Belova
L A
LA
Shevchenko
O P
OP
Dmitriev
A A
AA
D000328:Adult; D002918:Chymotrypsin / Q000037:antagonists & inhibitors / Q000097:blood*; D004789:Enzyme Activation; D005112:Extracorporeal Circulation; D005260:Female; D006023:Glycoproteins; D006331:Heart Diseases / Q000201:enzymology* / Q000601:surgery; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors / Q000097:blood*; D011184:Postoperative Period; D014357:Trypsin / Q000097:blood*
D006023:Glycoproteins; D002918:Chymotrypsin; D010196:Pancreatic Elastase; D014357:Trypsin; C028665:urinastatin
Korrektsiia (in vitro) proteinazno-ingibitornogo ballansa v krovi bol'nykh posle kardiokhirurgicheskikh vmeshatel'stv.