title: A method for calculating the optimum irradiation condition for intracavitary radiotherapy using quadratic programming.
abstract: A method of calculating optimum irradiation conditions for intracavitary radiotherapy using quadratic programming has been formulated and then modified for practical application. The allowable range of obtained dose, which is usually fixed in advance, is automatically computed to be as small as possible. The variance of the product of the activity and the irradiation time of the tandem source is also minimised to avoid the occurrence of cold and/or hot spots. Optimum irradiation conditions for conventional intracavitary radiotherapy of carcinoma of the uterine cervix were obtained on the basis of isodose curves passed through the points A of the Manchester system. Those for carcinoma of the other organs and special cases of carcinoma of the uterine cervix can be determined after consideration of the tumour state.
authors.affiliation: Department of Radiology, Saitama Cancer Center, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tabushi
authors.forename: S
authors.initials: S
authors.lastname: Itoh
authors.forename: M
authors.initials: M
authors.lastname: Sakura
authors.forename: Y
authors.initials: Y
authors.lastname: Kutsutani-Nakamura
authors.forename: T A
authors.initials: TA
authors.lastname: Iinuma
authors.forename: T
authors.initials: T
authors.lastname: Arai
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D003198:Computer Simulation; D005260:Female; D006801:Humans; D011880:Radiotherapy Planning, Computer-Assisted; D011881:Radiotherapy, Computer-Assisted; D012984:Software; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy