title: Trypanosoma congolense: the distribution of enzymic variants in east and west Africa.
abstract: A total of 114 stocks of Trypanosoma congolense originating from Kenya, Uganda, Tanzania, Zambia and Sudan, but including, for comparison, stocks from The Gambia, Liberia, Ivory Coast, Nigeria and Cameroun, were compared by isoenzyme electrophoresis for 6 enzymes. The zymodemes were grouped, both from a dendrogram and using a cladistic method, after calculating the dissimilarity, or distance, between profiles. Previous observations are broadly confirmed, the zymodemes clustering separately according to geographical origin and ecological zone. Thus, one group was composed almost entirely of East African stocks, and another of stocks from both East and West Africa, although each group was of savanna origin. A third group was composed of stocks from the humid, rain-forest zones of West Africa, and was particularly characterized by isoenzyme variants of superoxide dismutase and glucose-phosphate isomerase. Two stocks from the Kenyan coast formed a markedly separate group, which may be taxonomically distinct.
authors.affiliation: Department of Medical Protozoology, London School of Hygiene and Tropical Medicine, St Albans, Herts.
authors.forename: J K
authors.initials: JK
authors.lastname: Gashumba
authors.forename: R D
authors.initials: RD
authors.lastname: Baker
authors.forename: D G
authors.initials: DG
authors.lastname: Godfrey
mesh_terms: D000351:Africa, Eastern; D000354:Africa, Western; D000818:Animals; D014644:Genetic Variation; D007527:Isoenzymes / Q000032:analysis*; D014348:Trypanosoma congolense / Q000145:classification* / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification
chemical_list: D007527:Isoenzymes