title: Successful long term oral zinc in florid Wilson's disease: a case report.
abstract: We describe the clinical course of a patient with florid, predominantly neurological, Wilson's disease who developed serious toxic effects of d-penicillamine therapy but responded well to long term oral zinc sulphate. A congenital portosystemic shunt has decompressed the portal bed adequately to prevent the development of varices. We also documented the return to normal of a grossly abnormal pancreolauryl test after withdrawal of zinc.
authors.affiliation: Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: U
authors.initials: U
authors.lastname: Kaur
authors.forename: P
authors.initials: P
authors.lastname: Bambery
authors.forename: S R
authors.initials: SR
authors.lastname: Bhushnurmath
authors.forename: S D
authors.initials: SD
authors.lastname: Deodhar
authors.forename: J B
authors.initials: JB
authors.lastname: Dilawari
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D003300:Copper / Q000652:urine; D006527:Hepatolenticular Degeneration / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007194:India; D008297:Male; D010396:Penicillamine / Q000009:adverse effects* / Q000627:therapeutic use; D013431:Sulfates / Q000627:therapeutic use*; D015032:Zinc / Q000627:therapeutic use*; D019287:Zinc Sulfate
chemical_list: D013431:Sulfates; D019287:Zinc Sulfate; D003300:Copper; D010396:Penicillamine; D015032:Zinc