title: The effects of irradiation on alaryngeal voice of totally laryngectomized patients.
abstract: The effects of radiation therapy on the ability of totally laryngectomized patients to produce voice and speech were examined using objective non-invasive methods. Moderate to severe losses were noted in patients producing voice with all types of alaryngeal modalities: tracheoesophageal, esophageal, and electrolaryngeal. Voice and speech losses were related to the impaired motility and vibratory capability of the esophageal wall and mucosa, to fibrosis of the submandibular region and to trismus. Tracheoesophageal and esophageal voice was recovered some weeks after completion of irradiation. No voice losses were observed in alaryngeal speakers who did not undergo voice restoration until after irradiation. All irradiated patients also showed various degrees of dysphagia during the treatment.
authors.affiliation: Veterans Administration Medical Center, Martinez, CA 94553.
authors.forename: K
authors.initials: K
authors.lastname: Izdebski
authors.forename: J
authors.initials: J
authors.lastname: Fontanesi
authors.forename: J C
authors.initials: JC
authors.lastname: Ross
authors.forename: D
authors.initials: D
authors.lastname: Hetzler
mesh_terms: D006801:Humans; D007822:Laryngeal Neoplasms / Q000534:rehabilitation; D007825:Laryngectomy / Q000534:rehabilitation*; D007831:Larynx, Artificial; D008297:Male; D010315:Particle Accelerators; D011182:Postoperative Care / Q000379:methods*; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods*; D011879:Radiotherapy Dosage; D013071:Speech, Alaryngeal / Q000379:methods*; D013072:Speech, Esophageal; D013997:Time Factors; D014138:Tracheoesophageal Fistula; D014831:Voice / Q000528:radiation effects