(+/-)-9-Amino-1,2,3,4-tetrahydroacridin-1-ol. A potential Alzheimer's disease therapeutic of low toxicity.
Shutske
G M
GM
Department of Chemical Research, Hoechst-Roussel Pharmaceuticals, Inc., Somerville, New Jersey 08876.
Pierrat
F A
FA
Cornfeldt
M L
ML
Szewczak
M R
MR
Huger
F P
FP
Bores
G M
GM
Haroutunian
V
V
Davis
K L
KL
D000544:Alzheimer Disease / Q000188:drug therapy*; D000609:Aminoacridines / Q000627:therapeutic use*; D000818:Animals; D055598:Chemical Phenomena; D056486:Chemical and Drug Induced Liver Injury; D002621:Chemistry; D002800:Cholinesterase Inhibitors; D006801:Humans; D051379:Mice; D051381:Rats; D013619:Tacrine / Q000031:analogs & derivatives / Q000627:therapeutic use* / Q000633:toxicity
D000609:Aminoacridines; D002800:Cholinesterase Inhibitors; D013619:Tacrine; C056424:velnacrine