[Activity of the natural killer cells in the peripheral blood of patients with brain tumors].
Activity of natural killer cells (NK-cells) was determined in a 4-hour 51Cr-release test using K-562 as target cells in patients with brain tumours and donors. This activity was significantly (P less than 0.05) reduced in preoperative patients with metastatic brain tumours (mean--5.7%), gliomas of III-IV malignancy grades (mean--16.4%) as compared with the control (mean--32.5%). The activity of NK-cells remained low after surgical treatment irrespective of the length of remission.
Lisianyĭ
N I
NI
Markova
O V
OV
Zhmareva
E N
EN
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000276:immunology* / Q000556:secondary; D002478:Cells, Cultured; D002648:Child; D002860:Chromium Radioisotopes; D005260:Female; D005910:Glioma / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000276:immunology*; D008297:Male; D008577:Meningeal Neoplasms / Q000276:immunology*; D008579:Meningioma / Q000276:immunology*; D008875:Middle Aged
D002860:Chromium Radioisotopes
Aktivnost' estestvennykh killernykh kletok perifericheskoĭ krovi bol'nykh s opukholiami golovnogo mozga.