Fatal aplastic anemia in a patient treated with carbamazepine.
A case of fatal aplastic anemia due to carbamazepine treatment in an epileptic woman is reported. Despite concerns of fatal bone marrow toxicity due to carbamazepine, this is only the fourth documented and published report. Carbamazepine is a safe drug, but physicians and patients should be aware of the exceedingly rare but potentially fatal side effects, better prevented by clinical than by laboratory monitoring.
Franceschi
M
M
Department of Neurology, University of Milan, Italy.
Ciboddo
G
G
Truci
G
G
Borri
A
A
Canal
N
N
D000741:Anemia, Aplastic / Q000139:chemically induced*; D002220:Carbamazepine / Q000009:adverse effects*; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged
D002220:Carbamazepine