Anamnestic response of neonatal chickens to sheep red blood cells as influenced by the number of weeks between the first and second injections.
In two experiments primary and secondary hemagglutination titers of chickens were determined in response to intravenous injections of 1 mL of a 5% suspension of sheep red blood cells (SRBC). All birds received the primary injection at 4 wk of age. In the first experiment, equal numbers of male and female birds were randomly selected to receive the secondary injection at 2, 4, 6, and 8 wk following the initial injection. Based on the level of IgG antibody to SRBC, all postprimary injections affected an anamnestic response. Furthermore, the anamnestic response obtained following the 6 and 8-wk postprimary injection was significantly higher than those obtained with injections 2 or 4 wk after the primary injection. In the second experiment, secondary injections were administered either 3 or 6 wk after the primary injections. The anamnestic response of birds receiving the 6-wk postprimary injection was higher than those injected 3-wk after the primary injections.
Davis
V
V
College of Veterinary Medicine, Mississippi State University, Mississippi 39762.
Glick
B
B
D000818:Animals; D000917:Antibody Formation; D002645:Chickens / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006388:Hemagglutinins / Q000032:analysis*; D008297:Male; D012756:Sheep / Q000097:blood*
D006388:Hemagglutinins