title: Incidence of stroke in young adults in Florence, Italy.
abstract: A population-based study specifically addressing stroke in young adults (aged 15-44 years) was conducted in Florence, Italy, from 1983 to 1985. We identified 47 cases of first stroke by means of a daily check of the medical facilities of the city and nearby towns and a review of death certificates. Patients were assessed by a neurologist shortly after the onset of the stroke, and computed tomography or autopsy was performed in 96%. The average annual incidence rate for all stroke (cases per 100,000 population per year) was 9.0 (95% confidence interval 5.8-13.4) for males and 8.7 (95% confidence interval 5.5-13.0) for females. The average annual incidence rates for the pathologic types of stroke were 3.4 for cerebral infarction, 3.2 for subarachnoid hemorrhage, and 1.9 for intracerebral hemorrhage. The case-fatality ratio was 23.4% at 1 month. Among patients with ischemic strokes, atherosclerosis and cardiac disease accounted for 50% of the cases. Based on angiography or autopsy findings, aneurysm or arteriovenous malformation were demonstrated in 88% of the patients with subarachnoid hemorrhage. In 50% of the patients with intracerebral hemorrhage, no cause of bleeding was detected. Our study may supply information about stroke pathologic types in an unselected series of young adults.
authors.affiliation: Department of Neurology, University of Florence, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Nencini
authors.forename: D
authors.initials: D
authors.lastname: Inzitari
authors.forename: M C
authors.initials: MC
authors.lastname: Baruffi
authors.forename: L
authors.initials: L
authors.lastname: Fratiglioni
authors.forename: R
authors.initials: R
authors.lastname: Gagliardi
authors.forename: L
authors.initials: L
authors.lastname: Benvenuti
authors.forename: A M
authors.initials: AM
authors.lastname: Buccheri
authors.forename: L
authors.initials: L
authors.lastname: Cecchi
authors.forename: A
authors.initials: A
authors.lastname: Passigli
authors.forename: A
authors.initials: A
authors.lastname: Rosselli
mesh_terms: D000293:Adolescent; D000328:Adult; D002543:Cerebral Hemorrhage / Q000453:epidemiology; D002544:Cerebral Infarction / Q000453:epidemiology; D002561:Cerebrovascular Disorders / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D013345:Subarachnoid Hemorrhage / Q000453:epidemiology; D014505:Urban Population