title: Retained surgical swab debris in post-laminectomy arachnoiditis and peridural fibrosis.
abstract: We examined soft tissue biopsies from 26 patients with symptomatic nerve root fibrosis and arachnoiditis after a previous laminectomy. Dense fibrous connective tissue was found about the nerve roots and in 14 cases (55%) fibrillar foreign material was seen within it. This material had the histochemical characteristics of cotton fibres from swabs and neurosurgical patties. In two other cases nerve root fibrosis was associated with residual radiopaque lipid thought to derive from earlier myelography. Our findings suggest that risks may be associated with the introduction of foreign material into the vertebral canal, and that microscopic fragments of surgical swabs and patties may have a role in the pathogenesis of postoperative periradicular fibrosis.
authors.affiliation: Queen Elizabeth Hospital, Queen Elizabeth Medical Centre, Edgbaston, Birmingham, England.
authors.forename: J A
authors.initials: JA
authors.lastname: Hoyland
authors.forename: A J
authors.initials: AJ
authors.lastname: Freemont
authors.forename: J
authors.initials: J
authors.lastname: Denton
authors.forename: A M
authors.initials: AM
authors.lastname: Thomas
authors.forename: J J
authors.initials: JJ
authors.lastname: McMillan
authors.forename: M I
authors.initials: MI
authors.lastname: Jayson
mesh_terms: D000328:Adult; D000368:Aged; D001100:Arachnoiditis / Q000209:etiology* / Q000473:pathology; D001706:Biopsy; D004388:Dura Mater / Q000473:pathology; D005260:Female; D005355:Fibrosis / Q000209:etiology / Q000473:pathology; D005547:Foreign Bodies / Q000150:complications*; D006801:Humans; D007403:Intervertebral Disc / Q000601:surgery; D007796:Laminectomy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D013126:Spinal Nerve Roots / Q000473:pathology*