title: Non-invasive monitoring of ionic current flow during development by SQUID magnetometry.
abstract: The ionic currents flowing in developing organisms produce weak magnetic fields that can be detected using SQUID magnetometers. The method is non-invasive and dc recording is possible. To date SQUID magnetometers have mainly been used in human studies. The features of the technique are described and the prospects of extending its use to developmental studies are discussed. Feasible instrumental specifications are indicated. A recent SQUID magnetometer investigation of ionic current flow in the developing chick in ovo is summarised as an illustration of the magnetometer method. The paper as a whole argues that magnetometry is a useful alternative or adjunct to electrode-based experiments on the electrophysiology of developing organisms.
authors.affiliation: Physics Department, Open University, Milton Keynes, England.
authors.forename: S J
authors.initials: SJ
authors.lastname: Swithenby
mesh_terms: D000818:Animals; D002642:Chick Embryo; D004553:Electric Conductivity; D005544:Forecasting; D007477:Ions / Q000502:physiology*; D008280:Magnetics / Q000295:instrumentation; D009024:Morphogenesis
chemical_list: D007477:Ions