Pseudallescheria boydii brain abscess. Complication of an intravenous catheter.
An adult patient survived a brain abscess with Pseudallescheria boydii. She received intraventricular miconazole, 20 mg every 72 hours (minimal inhibitory concentration = 0.4 microgram/ml), and surgery. The abscess resulted from an infected central venous catheter (Port-A-Cath) and steroid therapy. Miconazole caused a ventriculitis. There are 12 reported cases of P. boydii brain abscesses from 1965 to 1985 with only two survivors.
Pérez
R E
RE
Infectious Disease Department, University of California, Irvine.
Smith
M
M
McClendon
J
J
Kim
J
J
Eugenio
N
N
D000328:Adult; D001203:Ascomycota / Q000302:isolation & purification*; D001922:Brain Abscess / Q000209:etiology* / Q000628:therapy; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008825:Miconazole / Q000627:therapeutic use; D009181:Mycoses / Q000209:etiology* / Q000628:therapy; D011541:Pseudallescheria / Q000302:isolation & purification*
D008825:Miconazole