title: [Animal experiment studies of morphologic changes in the trachea and lung in high frequency ventilation].
abstract: Prolonged high frequency ventilation (24 hrs) in dogs leads to morphological changes in the trachea as well as in the bronchi. Erosive changes of tracheal epithelium were observed whereas small bronchi and bronchioli exhibited luminal obstructions by mucus plugs, caused by hypersecretion of goblet cells. Using histochemical methods degenerative changes of bronchiolar epithelium were observed.
authors.affiliation: Forschungsinstitut für Lungenkrankheiten und Tuberkulose, Berlin-Buch/DDR.
authors.forename: H
authors.initials: H
authors.lastname: Eckert
authors.forename: E
authors.initials: E
authors.lastname: Danzmann
authors.forename: H
authors.initials: H
authors.lastname: Voigt
authors.forename: A
authors.initials: A
authors.lastname: Oddoy
authors.forename: G
authors.initials: G
authors.lastname: Merker
authors.forename: E
authors.initials: E
authors.lastname: Harzendorf
authors.forename: M
authors.initials: M
authors.lastname: Bomm
authors.forename: K
authors.initials: K
authors.lastname: Noack
authors.forename: E
authors.initials: E
authors.lastname: Ritzau
mesh_terms: D000818:Animals; D001980:Bronchi / Q000473:pathology; D004285:Dogs; D004848:Epithelium / Q000473:pathology; D005260:Female; D006612:High-Frequency Ventilation; D008168:Lung / Q000473:pathology*; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D011650:Pulmonary Alveoli / Q000473:pathology; D011663:Pulmonary Surfactants / Q000378:metabolism; D014132:Trachea / Q000473:pathology*
chemical_list: D011663:Pulmonary Surfactants
vernacular_title: Tierexperimentelle Untersuchungen zu morphologischen Veränderungen an Trachea und Lunge bei Hochfrequenzbeatmung.