title: Hemorrhagic pulmonary edema associated with meat tenderizer treatment for esophageal meat impaction.
abstract: We describe a case of acute hemorrhagic pulmonary edema caused by aspiration of Adolph's meat tenderizer, used in an attempt to relieve an esophageal meat impaction. We performed an animal experiment in which bronchial instillation of a similar solution reproduced the clinical findings in our patient. This is a previously unreported and potentially lethal complication of a therapy that has never been submitted to clinical trials. We recommend against the use of this therapy for patients with complete esophageal obstruction or in those otherwise at risk for aspiration.
authors.affiliation: Department of Medicine, University of Washington, Seattle.
authors.forename: M L
authors.initials: ML
authors.lastname: Hall
authors.forename: J S
authors.initials: JS
authors.lastname: Huseby
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000818:Animals; D004285:Dogs; D004947:Esophagus; D005547:Foreign Bodies / Q000628:therapy*; D006470:Hemorrhage / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D001239:Inhalation; D008171:Lung Diseases / Q000139:chemically induced / Q000473:pathology; D008297:Male; D010206:Papain / Q000008:administration & dosage / Q000009:adverse effects*; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011859:Radiography
chemical_list: D010206:Papain