title: Basilar artery giant fusiform aneurysms caused by congenital defect of the internal elastic lamina and media.
abstract: Giant fusiform aneurysms of the basilar artery were found in a 6-year-old boy who subsequently died after rupture of the aneurysm, and in a 64-year-old man who showed signs of ischemia and compression of the brain stem. Autopsy disclosed strikingly similar abnormalities of the wall of the basilar artery, consisting of a defect of the internal elastic lamina and absence of the media. A congenital anomaly may play a role in the pathogenesis of this abnormality, in both young and some elderly patients.
authors.affiliation: Department of Neurology, University Hospital Dijkzigt, Rotterdam, The Netherlands.
authors.forename: C A
authors.initials: CA
authors.lastname: van Donselaar
authors.forename: S Z
authors.initials: SZ
authors.lastname: Stefanko
authors.forename: T H
authors.initials: TH
authors.lastname: van der Kwast
authors.forename: W F
authors.initials: WF
authors.lastname: Arts
authors.forename: P J
authors.initials: PJ
authors.lastname: Koudstaal
mesh_terms: D001488:Basilar Artery / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D002675:Child, Preschool; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011859:Radiography