title: Towards a molecular mechanism for the crossbridge cycle.
abstract: Present evidence on crossbridge behaviour is reviewed from the viewpoint of the Eisenberg-Hill concepts. We conclude that a cartoon illustrating the operation of these ideas in practice should be drawn so as to include morphological changes in the body of the myosin molecule as part of the power-stroke. The bulk of structural evidence on the operation of crossbridges in intact muscle supports such a description.
authors.affiliation: Abteilung Biophysik, Max-Planck-Institut für Medizinische Forschung, Heidelberg, F.R.G.
authors.forename: J S
authors.initials: JS
authors.lastname: Wray
authors.forename: R S
authors.initials: RS
authors.lastname: Goody
authors.forename: K C
authors.initials: KC
authors.lastname: Holmes
mesh_terms: D000818:Animals; D008954:Models, Biological; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology*; D009210:Myofibrils / Q000502:physiology; D009218:Myosins / Q000502:physiology*
chemical_list: D009218:Myosins