title: Treatment response in malignant optic glioma of adulthood.
abstract: Two adults with malignant optic gliomas displayed dramatic tumor shrinkage and prolonged survival after radiation therapy alone in one case and combined radiation and chemotherapy in the other. Although malignant optic gliomas have been reported to be radiation resistant, marked treatment response may occur and aggressive treatment protocols should be considered.
authors.affiliation: Department of Neurology, Stanford University Medical Center, CA 94305.
authors.forename: G W
authors.initials: GW
authors.lastname: Albers
authors.forename: W F
authors.initials: WF
authors.lastname: Hoyt
authors.forename: L S
authors.initials: LS
authors.lastname: Forno
authors.forename: L A
authors.initials: LA
authors.lastname: Shratter
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001973:Bromodeoxyuridine / Q000627:therapeutic use; D003390:Cranial Nerve Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D005910:Glioma / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008130:Lomustine / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009901:Optic Nerve Diseases / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D011344:Procarbazine / Q000008:administration & dosage; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D011344:Procarbazine; D014750:Vincristine; D008130:Lomustine; D001973:Bromodeoxyuridine