title: Hb Tunis [alpha 2 beta 2 124 (H2)Pro----Ser], a new beta chain variant identified by HPLC.
abstract: During a routine hematological investigation of a child from Tunis, a silent hemoglobin variant was discovered by isoelectric-focusing. This variant was not detectable by conventional electrophoretic methods, had normal stability, expression, and oxygen affinity, and did not produce any clinical symptoms. This new variant beta 124(H2)Pro----Ser was named Hb Tunis.
authors.affiliation: Hôpital Habib Thameur, Tunis, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Mrad
authors.forename: Y
authors.initials: Y
authors.lastname: Blouquit
authors.forename: C
authors.initials: C
authors.lastname: Lacombe
authors.forename: R
authors.initials: R
authors.lastname: Blibech
authors.forename: N
authors.initials: N
authors.lastname: Arous
authors.forename: J
authors.initials: J
authors.lastname: Bardakdjian
authors.forename: R
authors.initials: R
authors.lastname: Kastally
authors.forename: J
authors.initials: J
authors.lastname: Rosa
authors.forename: F
authors.initials: F
authors.lastname: Galacteros
mesh_terms: D000596:Amino Acids / Q000032:analysis*; D002648:Child; D002851:Chromatography, High Pressure Liquid; D006455:Hemoglobins, Abnormal / Q000032:analysis* / Q000235:genetics; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D010375:Pedigree
chemical_list: D000596:Amino Acids; D006455:Hemoglobins, Abnormal; C056330:hemoglobin Tunis