title: Long-term followup of maximum concentrating ability and glomerular filtration rate in adult obstructed kidneys after pyeloplasty.
abstract: We investigated 34 patients with obstructed kidneys preoperatively and 8 to 10 years postoperatively concerning the separate glomerular filtration rate and maximum concentration ability. The mean glomerular filtration rate for the obstructed kidneys was approximately 10 per cent lower compared to that for the contralateral kidneys preoperatively and at followup. Although the mean value for obstructed kidneys was not improved at followup, kidneys with a decreased glomerular filtration rate preoperatively improved significantly after pyeloplasty. The maximum concentration ability was low preoperatively for the obstructed kidneys compared to the contralateral kidneys. The lowest maximum concentration ability was found in patients with a history of repeated upper urinary tract infections. At followup marked improvement was noted, which was most obvious for kidneys with severely reduced concentration ability preoperatively. However, the restoration was not total. There was a positive correlation between the improvement in glomerular filtration rate and improvement in maximum concentration ability.
authors.affiliation: Department of Urology, Sahlgrenska sjukhuset, Göteborg, Sweden.
authors.forename: C G
authors.initials: CG
authors.lastname: Bratt
authors.forename: M
authors.initials: M
authors.lastname: Aurell
authors.forename: O
authors.initials: O
authors.lastname: Jonsson
authors.forename: S
authors.initials: S
authors.lastname: Nilsson
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D006869:Hydronephrosis / Q000503:physiopathology / Q000601:surgery*; D007671:Kidney Concentrating Ability; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D014517:Ureteral Obstruction / Q000601:surgery