title: The relationship between waking time and urinary epinephrine in bed-rested humans under conditions involving minimal stress.
abstract: The correlation between urinary excretion of epinephrine and percent of waking time during time allotted for sleep was evaluated for both daytime and nighttime bed-rest under minimally stressful conditions. The experiment was performed on 6 male subjects. Polysomnographic recordings were made throughout each 8-h bed-rest period, and free epinephrine excretion was measured at intervals of 2.5 h. Epinephrine excretion showed a strongly positive correlation with percent of waking time during bed-rest in the daytime and at night (average correlation coefficient: day: r = 0.89, P less than 0.001; night: r = 0.68, P less than 0.001). The possibility that levels of epinephrine excretion could be used as an indicator of sleep disturbance is discussed.
authors.affiliation: Department of Psychophysiology, Psychiatric Research Institute of Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nishihara
authors.forename: K
authors.initials: K
authors.lastname: Mori
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology*; D001510:Bed Rest; D002940:Circadian Rhythm; D004837:Epinephrine / Q000652:urine*; D006801:Humans; D008297:Male; D012894:Sleep Stages / Q000502:physiology; D013315:Stress, Psychological / Q000652:urine*; D014851:Wakefulness / Q000502:physiology*
chemical_list: D004837:Epinephrine