title: Airway pressure-volume curve estimated by flow interruption during forced expiration.
abstract: The pressure-volume characteristics of the airway downstream to the choke point was estimated with abrupt interruption of airflow at the mouth during forced expiration. The pressure was measured at the mouth and the volume was given by the maximum flow immediately before interruption multiplied by interruption time. The compliance of the airway downstream to the choke point, i.e., a slope of the pressure-volume curve, was 1.04 ml/cmH2O at 50% FVC, and increased in lower lung volumes, in 7 healthy subjects. Whereas, in a case of tracheo-bronchopathia osteochondroplastica, its value decreased markedly.
authors.affiliation: Department of Internal Medicine, Kanazawa Medical University, Uchinada, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Ohya
authors.forename: J
authors.initials: J
authors.lastname: Huang
authors.forename: T
authors.initials: T
authors.lastname: Fukunaga
authors.forename: H
authors.initials: H
authors.lastname: Toga
mesh_terms: D000403:Airway Resistance; D005541:Forced Expiratory Volume; D006801:Humans; D010009:Osteochondrodysplasias / Q000503:physiopathology