[Excitation of mechanosensitive C-fiber sensory units of the skin in the cat by the intra-arterial administration of potassium ions].
In anaesthetized cats the responses of low- and high-threshold mechanosensitive C-fiber sensory units (MSU) in n. saphenus to close-arterial injection of potassium ions in subnoxious and noxious concentrations (SC and NC) have been studied. Two groups of high-threshold MSU were found: 1) MSU excited by K+ in NC only and 2) MSU responded to K+ both in SC and NC. The data suggest the nociceptive role of high-threshold MSU in contrast to low-threshold MSU. The possibility is discussed of a differentiation between subnoxious and noxious stimuli by a portion of high-threshold MSU. The characteristics of firing of high-threshold MSU are given which correlate with their excitation by noxious and subnoxious chemical stimuli.
Revenko
S V
SV
Ermishkin
V V
VV
Selektor
L Ia
LIa
D000818:Animals; D002415:Cats; D004305:Dose-Response Relationship, Drug; D005071:Evoked Potentials / Q000187:drug effects; D007269:Injections, Intra-Arterial; D009412:Nerve Fibers / Q000187:drug effects* / Q000502:physiology; D009619:Nociceptors / Q000187:drug effects* / Q000502:physiology; D011188:Potassium / Q000008:administration & dosage*; D012501:Saphenous Vein / Q000187:drug effects / Q000502:physiology; D012867:Skin / Q000294:innervation*; D013268:Stimulation, Chemical
D011188:Potassium
Vozbuzhdenie mekhanochuvstvitel'nykh sensornykh edinits gruppy C kozhi koshki pri vnutriarterial'nom vvedenii ionov kaliia.