[Effect of succinic acid on blood coagulability and the catecholamine balance].
A single administration of succinic acid was shown to cause a dose-dependent decrease of the blood coagulability in rats. Seven-day administration of succinic acid (50 mg/kg) resulted in a distinct increase of the blood coagulability, an accumulation of adrenaline in the heart and adrenal gland tissues. Hypercoagulation was noted on the 5th day after withdrawal of succinic acid (50 and 200 mg/kg).
Nikulin
A A
AA
Khrapova
S I
SI
Tebiakina
E A
EA
Rachkov
A K
AK
Semenchenko
M V
MV
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001808:Blood Vessels / Q000187:drug effects; D002395:Catecholamines / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008297:Male; D009206:Myocardium / Q000378:metabolism; D011898:Ranidae; D051381:Rats; D013386:Succinates / Q000494:pharmacology*; D019802:Succinic Acid; D013997:Time Factors
D002395:Catecholamines; D013386:Succinates; D019802:Succinic Acid
K voprosu o vliianii iantarnoĭ kisloty na svertyvaemost' krovi i balans katekholaminov.