[Multiple forms of thrombocyte monoamine oxidase in patients with manic-depressive psychosis and recurrent schizophrenia].
The concentrations of different forms of monoamine oxidase (MAO) in platelets of the peripheral blood from healthy subjects (n = 13), patients with recurrent schizophrenia (n = 6) and those with manic depressive psychoses (n = 5) were measured. MAO of platelets of the peripheral blood from the control subjects and patients with the considered diseases consisted of three forms: MAO-1, MAO-2, and MAO-3. Analysis of the values of the specific activity of each of the studied forms failed to show any significant difference between the patients and controls. Comparison of the quantitative distribution of different forms of MAO in both groups revealed no difference between the groups with regard to MAO-2 and MAO-3 and a significant (P less than 0.01) decrease in MAO-1 (5.34 +/- 1.5%) in patients with mental diseases as compared to this parameter (19.0 +/- 6.5%) in the control group.
Smirnov
A V
AV
Prilipko
L L
LL
D000327:Adsorption; D000328:Adult; D001714:Bipolar Disorder / Q000201:enzymology*; D001792:Blood Platelets / Q000201:enzymology*; D002850:Chromatography, Gel; D002908:Chronic Disease; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000097:blood*; D012008:Recurrence; D012559:Schizophrenia / Q000201:enzymology*
D007527:Isoenzymes; D008995:Monoamine Oxidase
Mnozhestvennye formy trombotsitarnoĭ monoaminoksidazy u bol'nykh maniakal'no-depressivnym psikhozom i rekurrentnoĭ shizofrenieĭ.