Total sleep deprivation in patients with obsessive-compulsive disorder.
Total sleep deprivation was performed in 16 patients with obsessive-compulsive disorder. Overall, no effect was observed on either mood or obsessive-compulsive behaviour. However, individual patients showed worsening, improvement or no change in obsessive-compulsive symptoms, independent of mood response, across the 3 days of sleep deprivation.
Joffe
R T
RT
Department of Psychiatry, St. Michael's Hospital, Toronto, Canada.
Swinson
R P
RP
D000328:Adult; D004644:Emotions / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000628:therapy*; D012892:Sleep Deprivation