The gene coding a ubiquitin-activating enzyme may locate on X chromosome.
tsBN75 cells which have a ts defect in the S phase have a mutation linked to the gene of hypoxanthine phosphoribosyl transferase and cannot complement ts85 cells which have a ts defect in the ubiquitin-activating enzyme. The ubiquitin-activating enzyme may be required for completion of the S phase.
Ohtsubo
M
M
Department of Moleculer Biology, Graduate School of Medical Science Kyushu University, Fukuoka, Japan.
Nishimoto
T
T
D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D007399:Interphase; D008025:Ligases / Q000235:genetics*; D009154:Mutation; D044764:Ubiquitin-Activating Enzymes; D044767:Ubiquitin-Protein Ligases; D014960:X Chromosome
D044767:Ubiquitin-Protein Ligases; D008025:Ligases; D044764:Ubiquitin-Activating Enzymes