Plasma melatonin levels in patients suffering from colorectal carcinoma.
Plasma melatonin was determined in samples of patients with colorectal carcinoma and in controls using an iodinated radioimmunoassay. Both groups showed large individual variability in absolute melatonin levels. However, during the night, melatonin concentration in cancer patients was significantly lower than in controls.
Khoory
R
R
Centre of Human Genetics and Genetic Counselling, University of Bremen, Federal Republic of Germany.
Stemme
D
D
D000368:Aged; D000369:Aged, 80 and over; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002277:Carcinoma / Q000097:blood*; D002940:Circadian Rhythm; D003110:Colonic Neoplasms / Q000097:blood* / Q000276:immunology; D006801:Humans; D007206:Individuality; D008550:Melatonin / Q000097:blood* / Q000276:immunology; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000097:blood* / Q000276:immunology
D002272:Carcinoembryonic Antigen; D008550:Melatonin