title: Total sleep deprivation in patients with obsessive-compulsive disorder.
abstract: Total sleep deprivation was performed in 16 patients with obsessive-compulsive disorder. Overall, no effect was observed on either mood or obsessive-compulsive behaviour. However, individual patients showed worsening, improvement or no change in obsessive-compulsive symptoms, independent of mood response, across the 3 days of sleep deprivation.
authors.affiliation: Department of Psychiatry, St. Michael's Hospital, Toronto, Canada.
authors.forename: R T
authors.initials: RT
authors.lastname: Joffe
authors.forename: R P
authors.initials: RP
authors.lastname: Swinson
mesh_terms: D000328:Adult; D004644:Emotions / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000628:therapy*; D012892:Sleep Deprivation