Nucleotide sequence of the human theta 1-globin gene.
We have cloned and sequenced the human theta 1-globin gene. The nucleotide sequence and organization of the human theta 1 gene (exons, introns, promoter, and polyadenylation signals) are similar to those reported for the orangutan theta 1-globin gene. If these genes are functional, the sequences of their theta 1-globin chains would differ by only one amino acid residue (at position 137).
Gonzalez-Redondo
J M
JM
Department of Cell and Molecular Biology, Medical College of Georgia, Augusta 30912-3331.
Han
I S
IS
Gu
Y C
YC
Huisman
T H
TH
D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D005260:Female; D005796:Genes; D005914:Globins / Q000235:genetics*; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization
D005914:Globins