A sex cord stromal tumour in a woman with XO/XX/XXX-mosaicism.
We describe a postmenopausal woman with 45,XO/46,XX/47,XXX mosaicism who presented with a Sertoli-Leydig cell tumour and a past history of habitual abortion. The cytogenetic finding is discussed in relation to the etiology of the tumour and of the recurrent abortions.
Glaser
D
D
Institute for Human Genetics, Westfälische Wilhelms-Universität Münster, Federal Republic of Germany.
Nienhaus
H
H
Köhler
R
R
Walther
G
G
Pawlowitzki
I H
IH
D005260:Female; D006801:Humans; D007621:Karyotyping; D007984:Leydig Cell Tumor / Q000235:genetics; D009030:Mosaicism; D010051:Ovarian Neoplasms / Q000235:genetics*; D012707:Sertoli Cell Tumor / Q000235:genetics; D012729:Sex Chromosome Aberrations; D014960:X Chromosome