Vulvar dystrophies in young and premenopausal women.
Eighty-six cases of vulvar dystrophy in young and premenopausal women (age range, 6-53 years) were studied clinically and histopathologically. The most frequent symptom was pruritus associated with burning. Clinical examination showed the presence of white areas in 73% of the patients, red areas in 9% and other signs (such as melanosis) in 18%. Hyperplastic dystrophy was the most frequent type of dystrophy in these patients and was observed in 63% of cases. Cellular atypia was observed in 9.8% of the cases and was found almost exclusively in hyperplastic dystrophy. Epithelial changes suggestive of human papillomavirus infection were found in 4 of the 86 cases of dystrophy, and they were observed only in atypical dystrophies.
Barbero
M
M
Institute of Gynecology and Obstetrics, University of Turin, Italy.
Micheletti
L
L
Borgno
G
G
Cavanna
L
L
Preti
M
M
Ghiringhello
B
B
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007558:Italy; D008875:Middle Aged; D014845:Vulvar Diseases / Q000453:epidemiology / Q000473:pathology*