title: [Mitochondrial respiration and oxygen transport during various stages of lung inflammation].
abstract: It is shown in rats with experimental lung inflammation that the phosphorylative and uncoupling mitochondrial respiration intensity rises at acute and reverses to the normal level at subacute inflammation. At chronic inflammation the 2,4-DNP-stimulated mitochondrial respiration enhances and the ADPO coefficient lowers. At all stages of inflammation the pO2 rise in muscles after O2-inhalation is less than in healthy animals. The disturbance of O2 transport in organism may be the reason of the described low energy shift at lung inflammation.
authors.forename: V L
authors.initials: VL
authors.lastname: Semenov
mesh_terms: D000818:Animals; D001692:Biological Transport; D005260:Female; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D011014:Pneumonia / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
vernacular_title: Dykhanie mitokhondriĭ i transport kisloroda v organizme na raznykh stadiiakh vospaleniia legkikh.