title: Uptake of 99mTc labelled (Fab')2 fragments of monoclonal antibody 225.28S by a benign ocular naevus.
abstract: Malignant melanoma is one of the most common primary intraocular neoplasms. Recently, 99mTc radiolabelled (Fab')2 fragments of monoclonal antibody 225.28S raised against cutaneous melanomas have been used for imaging uveal melanomas. We report here a case where uptake of radiolabelled antibody was observed in a choroidal melanoma of the right eye and a benign choroidal naevus of the left.
authors.affiliation: Department of Nuclear Medicine, St Bartholomew's Hospital, London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Bomanji
authors.forename: J L
authors.initials: JL
authors.lastname: Hungerford
authors.forename: M
authors.initials: M
authors.lastname: Granowska
authors.forename: K E
authors.initials: KE
authors.lastname: Britton
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D002830:Choroid Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D007140:Immunoglobulin Fab Fragments; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging*; D009508:Nevus, Pigmented / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging
chemical_list: D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments