Effect of salai guggal ex-Boswellia serrata on cellular and humoral immune responses and leucocyte migration.
Effect of alcoholic extract of salai guggal (AESG) was studied on cellular and humoral immune responses in mice and leucocyte migration in rats. Oral administration of AESG strongly inhibited the antibody production and cellular responses to sheep red blood cells in mice. It inhibited the infiltration of polymorphonuclear leucocytes and reduced the volume of pleural exudate in carrageenan induced pleurisy in rats. It showed no cytotoxic effect.
Sharma
M L
ML
Pharmacology Department, Regional Research Laboratory, Jammu Tawi, India.
Khajuria
A
A
Kaul
A
A
Singh
S
S
Singh
G B
GB
Atal
C K
CK
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002465:Cell Movement / Q000187:drug effects; D007109:Immunity / Q000187:drug effects*; D008297:Male; D051379:Mice; D009504:Neutrophils / Q000187:drug effects* / Q000502:physiology; D010936:Plant Extracts / Q000494:pharmacology; D012116:Resins, Plant; D014315:Triterpenes / Q000494:pharmacology*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts; D012116:Resins, Plant; D014315:Triterpenes; C049844:salai guggal