Circadian rhythm of histamine metabolism in the rabbit central nervous system (CNS): analysis of brain and ocular structures.
The circadian rhythm of the level of histamine (HI) and histidine decarboxylase (HD) and histamine-methyltransferase (HMT) activity in 6 brain and 5 ocular structures of the rabbit was studied. Clear circadian variations of the histaminergic parameters in two brain (hypothalamus and lateral geniculate body) and two ocular (retina and iris-ciliary body) tissues were found. It is suggested that HI in some brain and ocular structures may be functionally involved in activity that depends on circadian rhythm.
Nowak
J Z
JZ
Department of Biogenic Amines, Polish Academy of Sciences, Lódź.
Socko
R
R
Uznanski
P
P
D000818:Animals; D001921:Brain / Q000378:metabolism; D002490:Central Nervous System / Q000378:metabolism*; D002940:Circadian Rhythm; D005123:Eye / Q000378:metabolism; D006632:Histamine / Q000378:metabolism*; D006637:Histamine N-Methyltransferase / Q000378:metabolism; D006640:Histidine Decarboxylase / Q000378:metabolism; D008297:Male; D011817:Rabbits; D014018:Tissue Distribution
D006632:Histamine; D006637:Histamine N-Methyltransferase; D006640:Histidine Decarboxylase