title: Chiari I malformation with quadriplegia and respiratory disturbance in an infant.
abstract: Chiari I malformation consists of variable downward displacement of the cerebellar tonsils. Quadriplegia, respiratory disturbance and pain are common in Chiari I malformation in adults. However, there are no reports of this syndrome in early childhood. We report the case of a 9-month-old girl with Chiari I malformation who had quadriplegia with muscle weakness and who developed respiratory disturbance as an early symptom. The causes of the symptoms of Chiari I malformation are discussed. The use of MRI is proposed as a more useful diagnostic technique than myelography for these patients since MRI is less likely to aggravate the respiratory disturbance.
authors.affiliation: Department of Pediatrics, Osaka University Medical School, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Itoh
authors.forename: T
authors.initials: T
authors.lastname: Mimaki
authors.forename: T
authors.initials: T
authors.lastname: Tagawa
authors.forename: T
authors.initials: T
authors.lastname: Sugita
authors.forename: H
authors.initials: H
authors.lastname: Yabuuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Ushio
mesh_terms: D000367:Age Factors; D001139:Arnold-Chiari Malformation / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D011782:Quadriplegia / Q000209:etiology*; D012120:Respiration Disorders / Q000209:etiology*