title: Protection of the rat lung from the harmful effects of laser smoke.
abstract: Fourteen Sprague-Dawley rats were exposed to CO2 laser exhaust that had first passed through smoke-evacuator filters. Six rats breathed laser vapors that were filtered through commercially available, standard production model smoke-evacuator systems. These animals demonstrated pulmonary lesions identical to but qualitatively less severe than those observed in animals breathing unfiltered vapor. Six additional rats were protected by the interposition of a cartridge filter plus an ultra-low penetration air filter, which trapped 0.1 micron particles; the microscopic sections of the lungs of these experimental rats and two control rats were similar in appearance, i.e., no pathological changes were observed.
authors.affiliation: Department of Obstetrics and Gynecology, SUNY Health Science Center, Syracuse 13210.
authors.forename: M S
authors.initials: MS
authors.lastname: Baggish
authors.forename: P
authors.initials: P
authors.lastname: Baltoyannis
authors.forename: E
authors.initials: E
authors.lastname: Sze
mesh_terms: D000818:Animals; D005374:Filtration / Q000295:instrumentation*; D007834:Lasers / Q000009:adverse effects; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000473:pathology / Q000517:prevention & control*; D011658:Pulmonary Fibrosis / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D012906:Smoke / Q000009:adverse effects*; D014462:Ultrafiltration / Q000295:instrumentation
chemical_list: D012906:Smoke