title: The role of lectins and lipoteichoic acid in adherence of Staphylococcus saprophyticus.
abstract: Staphylococcus saprophyticus strains S 1 and S 35 demonstrated lectin like surface receptors specific for N-acetylgalactosamine (S 1) or N-acetylneuraminic acid (S 35). Adhesion assays with human uroepithelial cells together with blocking experiments with competitive carbohydrates suggested that specific attachment of S. saprophyticus to host cells is apparently mediated by lectins. Staphylococcal lipoteichoic acid (LTA) was also shown to interfere with S. saprophyticus adherence to human uroepithelial cells.
authors.affiliation: Hygiene-Institut der Universität, Köln.
authors.forename: J
authors.initials: J
authors.lastname: Beuth
authors.forename: H L
authors.initials: HL
authors.lastname: Ko
authors.forename: Y
authors.initials: Y
authors.lastname: Ohshima
authors.forename: A
authors.initials: A
authors.lastname: Yassin
authors.forename: G
authors.initials: G
authors.lastname: Uhlenbruck
authors.forename: G
authors.initials: G
authors.lastname: Pulverer
mesh_terms: D001422:Bacterial Adhesion; D002478:Cells, Cultured; D004848:Epithelium / Q000382:microbiology; D006386:Hemagglutination Tests; D006801:Humans; D037102:Lectins / Q000378:metabolism*; D008070:Lipopolysaccharides / Q000378:metabolism*; D013210:Staphylococcus / Q000378:metabolism*; D013682:Teichoic Acids / Q000378:metabolism*; D014551:Urinary Tract / Q000382:microbiology*
chemical_list: D037102:Lectins; D008070:Lipopolysaccharides; D013682:Teichoic Acids; C009900:lipoteichoic acid