[Comparative study in an experiment on the efficacy of 2 regimens of vaccinal immunization against human acute encephalomyelitis].
Experimental data on the effectiveness of two schedules of vaccination against human acute encephalomyelitis, one conventional, using 12 injections, and another shortened, using 8 injections, are presented. The experiments in inbred mice evaluating the general resistance, virus-neutralizing antibody titres, resistance in adoptive transfer tests, and values of lymphocyte blastogenesis test showed no statistically significant differences between the shortened vaccination schedule and the conventional one. Experimentally, the shortened vaccination schedule is as effective as the conventional one.
Ignat'ev
G M
GM
Gribencha
S V
SV
Vorob'eva
M S
MS
Barinskiĭ
I F
IF
D000818:Animals; D000917:Antibody Formation; D004353:Drug Evaluation, Preclinical; D004679:Encephalomyelitis / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D007111:Immunity, Cellular; D007114:Immunization / Q000379:methods*; D007115:Immunization Schedule; D007117:Immunization, Secondary; D051379:Mice; D008808:Mice, Inbred CBA; D013997:Time Factors; D014765:Viral Vaccines / Q000008:administration & dosage* / Q000276:immunology
D014765:Viral Vaccines
Sravnitel'noe izuchenie v éksperimente éffektivnosti dvukh skhem immunizatsii vaktsinoĭ protiv ostrogo éntsefalomielita cheloveka.