title: Plasma catecholamine concentrations--changes after infiltration with local anaesthetic solutions and adrenaline during bat-ear surgery.
abstract: Plasma catecholamine concentrations were measured in 12 patients who had bilateral bat-ear surgery following infiltration of each ear with 2 ml 2% lignocaine with adrenaline 1:100,000. Venous blood samples were withdrawn before and at set intervals after infiltration. Plasma adrenaline concentration increased from 0.8 pmol/ml to a peak of 2.2 pmol/ml at 2 minutes after infiltration; this is an increase of 175%. There was no significant change in plasma noradrenaline concentration.
authors.affiliation: University Department of Anaesthesia, Leicester Royal Infirmary.
authors.forename: J K
authors.initials: JK
authors.lastname: Lew
authors.forename: K A
authors.initials: KA
authors.lastname: Mobley
authors.forename: K J
authors.initials: KJ
authors.lastname: Achola
authors.forename: G
authors.initials: G
authors.lastname: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000772:Anesthesia, Local; D001794:Blood Pressure / Q000187:drug effects; D002395:Catecholamines / Q000097:blood*; D004431:Ear, External / Q000002:abnormalities / Q000601:surgery; D004837:Epinephrine / Q000008:administration & dosage* / Q000097:blood / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage* / Q000494:pharmacology; D009638:Norepinephrine / Q000097:blood
chemical_list: D002395:Catecholamines; D008012:Lidocaine; D009638:Norepinephrine; D004837:Epinephrine