Colonic lymphoid follicles associated with colonic neoplasms.
In 3,399 patients more than 40 years of age undergoing air-contrast enema examinations a prospective evaluation was done for the presence of colonic lymphoid follicles. In 3,315 patients there was no evidence of lymphoid follicles. Colonic neoplasms were diagnosed in 8.47% of these individuals. Eighty-four patients were found to have radiographically identifiable follicles. Fifty-eight of these 84 patients (69%) with lymphoid follicles had a synchronous (n = 19) or previous (n = 14) colonic neoplasm or a synchronous (n = 24) or previous (n = 1) colonic polyp. There were no consistent clinical or radiographic features that distinguished the patients with and without a neoplastic association. However, 90% of men with lymphoid follicles had associated neoplasms, whereas only 58% of women did. Because of the frequent association, detection of colonic lymphoid follicles in patients in this age group should lead to a vigorous search for subtle colonic neoplasms that may not be apparent because of technical limitations of the study.
Glick
S N
SN
Department of Diagnostic Radiology, Hahnemann University Hospital, Philadelphia, PA 19102.
Teplick
S K
SK
Ross
W M
WM
D000328:Adult; D000368:Aged; D001466:Barium Sulfate; D002277:Carcinoma / Q000000981:diagnostic imaging*; D003106:Colon / Q000000981:diagnostic imaging*; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging*; D003111:Colonic Polyps / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008221:Lymphoid Tissue / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011029:Pneumoradiography; D011446:Prospective Studies; D012307:Risk Factors
D001466:Barium Sulfate