[The function of the reticuloendothelial system studied with the use of radioactive colloids].
A new method for the interpretation of data obtained during radionuclide investigation of the reticuloendothelial system (RES) was proposed. It was based on a detailed description of the mechanism of reticuloendothelial extraction of a colloid injected intravenously. A model developed for this purpose included the main stages of radioactive colloid transport. The paper also represented a comparative analysis of the results of clinical examination of the controls and patients with liver cirrhosis. A 4-fold decrease of the blood flow in portal liver cirrhosis was noted as compared with normal mean indices in a 2-fold decrease in the specific blood supply of cells of the RES and in a 2-fold decrease in its volume. An increase in phagocytosis rate in patients with liver cirrhosis needs further verification.
Parfenov
A S
AS
Bondareva
I B
IB
Rudakov
A V
AV
D000465:Algorithms; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008102:Liver Circulation; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D012157:Mononuclear Phagocyte System / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011877:Radionuclide Imaging; D013671:Technetium Tc 99m Sulfur Colloid / Q000008:administration & dosage
D013671:Technetium Tc 99m Sulfur Colloid
Izuchenie funktsii retikuloéndotelial'noĭ sistemy s pomoshch'iu radioaktivnykh kolloidov.