Calcium absorption: effect of meal and glucose polymer.
Various nonelectrolyte meal components such as glucose and lysine enhance gastrointestinal calcium absorption under experimental conditions. The effect of a mixed meal on Ca absorption from Ca supplements is unknown. The effect of glucose polymer on Ca absorption when ingested with food also is unknown. Using a single-day method, we measured net Ca absorption from Ca carbonate when ingested in fasting state, with a steak and potatoes meal, and with the meal and 50 g glucose polymer. Eight healthy human subjects were studied after a 500-mg elemental Ca dose. Mean net Ca absorption was 195 +/- 18 mg (4.87 +/- 0.45 mmol) fasting, 213 +/- 21 mg (5.31 +/- 0.52 mmol) with a meal, and 179 +/- 16 mg (4.47 +/- 0.40 mmol) with a meal plus glucose polymer. The differences are not statistically significant. In normal people Ca absorption from Ca carbonate was not significantly enhanced by a meal or by 50 g glucose polymer ingested with food.
Sheikh
M S
MS
Department of Internal Medicine, Baylor University Medical Center, Dallas, TX.
Santa Ana
C A
CA
Nicar
M J
MJ
Schiller
L R
LR
Fordtran
J S
JS
D000328:Adult; D002117:Calcitriol / Q000097:blood; D002118:Calcium / Q000493:pharmacokinetics*; D002119:Calcium Carbonate / Q000378:metabolism; D005502:Food; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D007408:Intestinal Absorption; D008297:Male; D011108:Polymers
D011108:Polymers; D002117:Calcitriol; D002119:Calcium Carbonate; D005947:Glucose; D002118:Calcium