Telomeric association: another characteristic of cancer chromosomes?
Telomeric associations between single chromatids and double chromatids of nonhomologous normal human chromosomes and altered markers were observed in two morphologically distinct squamous-cell carcinoma lines derived from a surgical specimen. Chromosomes 2, 3, 5, and 16 were associated by their telomeric ends more frequently than other chromosomes.
Department of Cell Biology, University of Texas, M.D. Anderson Hospital and Tumor Institute, Houston 77030.
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Pathak
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Wang
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Dhaliwal
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Sacks
D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000648:ultrastructure; D002842:Chromatids / Q000648:ultrastructure; D002869:Chromosome Aberrations; D006801:Humans; D008297:Male; D008875:Middle Aged; D014407:Tumor Cells, Cultured