The genitourinary system in patients with imperforate anus.
The incidence and significance of associated genitourinary abnormalities was reviewed in a series of 484 infants with imperforate anus encountered over a 17-year period. Fourteen percent of the entire series had significant bilateral upper tract urinary abnormalities (either asymmetric or symmetric). Of 67 such patients only 14 had combinations of renal agenesis and hypoplasia-dysplasia representing uncorrectable renal pathology. A high incidence of vesicoureteral reflex and neurovesical dysfunction represent additional important sources of preventable renal deterioration.
Division of Pediatric Urology, Hospital for Sick Children, Toronto, Ontario.
G A
GA
McLorie
C A
CA
Sheldon
M
M
Fleisher
B M
BM
Churchill
D001006:Anus, Imperforate / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000209:etiology; D008297:Male; D013131:Spine / Q000002:abnormalities; D014548:Urinary Fistula / Q000453:epidemiology / Q000473:pathology; D014564:Urogenital Abnormalities; D014566:Urogenital System / Q000473:pathology; D014624:Vaginal Fistula / Q000453:epidemiology / Q000473:pathology