Simultaneous upgrading reaction and erythema nodosum leprosum in a patient with lepromatous leprosy.
A case of lepromatous leprosy with erythema nodosum leprosum (ENL) undergoing treatment with dapsone, rifampin, and thalidomide developed focal tuberculoid granulomas in the ENL lesions. This is the first report known to the authors of a lepromatous leprosy patient in whom ENL and an upgrading reaction occurred simultaneously.
Job
C K
CK
Pathology Research Department, Hansen's Disease Center, Carville, Louisiana 70721.
Jacobson
R R
RR
Hastings
R C
RC
D000328:Adult; D001706:Biopsy; D004893:Erythema Nodosum / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007918:Leprosy / Q000276:immunology / Q000473:pathology*; D008297:Male; D012867:Skin / Q000473:pathology*