[Intravenous-intramuscular bioequivalency of ceftriaxone in newborn infants].
In 6 neonates over 7 days of life, comparison of maximum and residual serum concentrations of ceftriaxone after intra-venous or intra-muscular administration showed the bio-equivalence of both ways. In both cases a single daily injection obtained bacterial serum levels on most of the strains responsible for secondary bacterial infections in neonates.
Service de Pédiatrie et Réanimation néonatales, Hôpital Antoine-Béclère, Clamart.
M A
MA
Saby
M
M
Guibert
J F
JF
Magny
J P
JP
Praud
J L
JL
Chabernaud
M
M
Dehan
J C
JC
Gabilan
D001682:Biological Availability; D002443:Ceftriaxone / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006801:Humans; D007231:Infant, Newborn / Q000378:metabolism*; D007262:Infusions, Intravenous; D007273:Injections, Intramuscular
D002443:Ceftriaxone
Etude de la bioéquivalence intraveineuse-intramusculaire de la ceftriaxone chez le nouveau-né.