[Effect of synthetic fragments of thymic peptide hormones on learning and memory processes].
Seven synthetic peptide fragments of thymic hormones were investigated using behavioral and electrophysiological methods. Splenopentin was shown to increase markedly learning capacities and memory. In contrast, alpha 1-thymosin fragment decreased them. Other peptides only slightly affected the capacities. Two active peptides seem to affect the level of activation of subcortical structures responsible for the excitation and inhibition.
Martynov
V F
VF
Leont'eva
L I
LI
Sorochinskaia
E I
EI
D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography; D005260:Female; D006728:Hormones / Q000494:pharmacology*; D007858:Learning / Q000187:drug effects* / Q000502:physiology; D008297:Male; D008568:Memory / Q000187:drug effects* / Q000502:physiology; D010446:Peptide Fragments / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D012919:Social Behavior; D013951:Thymus Hormones / Q000494:pharmacology*
D006728:Hormones; D010446:Peptide Fragments; D013951:Thymus Hormones
Vliianie sinteticheskikh fragmentov peptidnykh gormonov timusa na protessy obucheniia i pamiati.