[Experimental oxalic lithiasis. Crystallographic study].
An intense oxalo-calcium nephrocalcinosis can be produced in rats, by the experimental use of substances such as glyoxylic acid and ethylene-glycol which can be transformed into oxalic acid within the organism. So can it be possible to make the crystallographic study of the crystal precipitations induced after administering those substances. For that purpose we have used a total number of 24 rats to which the above mentioned substances were administered, at different doses and by different methods. Thus, an intense parenchymatous crystalline precipitation was obtained, which allowed us to study the structure of those crystals by means of C. Zeiss photomicroscope. The results obtained in the different groups studied were similar. A much higher presence of crystals of monohydrate calcium oxalate was observed, although crystals of dihydrate were also found, although some of them under clear process of transformation into monohydrate form.
Départment de Chirurgie, Hôpital Clínico Universitario, Grenade, Espagne.
J L
JL
Mijan Ortiz
A
A
Zuluaga Gomez
A
A
De La Fuente Serrano
A
A
Ben el Haddad
D000818:Animals; D002129:Calcium Oxalate / Q000032:analysis*; D003461:Crystallography; D005026:Ethylene Glycols; D006038:Glyoxylates; D009397:Nephrocalcinosis / Q000139:chemically induced / Q000378:metabolism*; D051381:Rats
D005026:Ethylene Glycols; D006038:Glyoxylates; D002129:Calcium Oxalate; C031150:glyoxylic acid
Lithiase oxalique expérimentale. Etude cristallographique.