Suprasellar craniopharyngioma associated with hyperprolactinemia, pituitary lactotroph hyperplasia, and microprolactinoma. Case report.
A case with the coexistence of a microprolactinoma and suprasellar craniopharyngioma lactotroph hyperplasia is presented. Loss of inhibitory hypothalamic dopaminergic input may have played a role in hyperprolactinemia and the proliferation of pituitary lactotrophs. This is believed to be the first published case of suprasellar craniopharyngioma with this association.
Cusimano
M D
MD
Department of Pathology, St. Michael's Hospital, University of Toronto, Ontario, Canada.
Kovacs
K
K
Bilbao
J M
JM
Tucker
W S
WS
Singer
W
W
D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D003397:Craniopharyngioma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D006965:Hyperplasia; D006966:Hyperprolactinemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010902:Pituitary Gland / Q000378:metabolism / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000150:complications / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism*; D012658:Sella Turcica
D011388:Prolactin