Gene conversion in avian mesotocin and vasotocin genes: a recurrent mechanism linking two neurohypophysial precursor lineages?
Amino acid sequences of the first half of MSEL- and VLDV-neurophysins from goose and chicken have been determined. Identical substitutions in positions 17, 18, 35, 36 and 41 of both neurophysins of a given species when compared with their mammalian counterparts suggest a gene conversion between vasotocin--MSEL-neurophysin and mesotocin--VLDV-neurophysin genes. This event, which has already been observed for three mammalian species, seems recurrent and would link the evolution of the two neurohypophysial hormone precursors.
Lévy
B
B
Laboratory of Biological Chemistry, University of Paris VI, France.
Michel
G
G
Chauvet
J
J
Chauvet
M T
MT
Acher
R
R
D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D002645:Chickens; D005777:Geese; D005785:Gene Conversion; D008040:Genetic Linkage; D008969:Molecular Sequence Data; D009481:Neurophysins / Q000235:genetics; D010121:Oxytocin / Q000031:analogs & derivatives* / Q000235:genetics; D014668:Vasotocin / Q000235:genetics*
D009481:Neurophysins; C001713:mesotocin; D010121:Oxytocin; D014668:Vasotocin