Release of 3,5,3'-triiodothyronine, thyroxine and thyroglobulin from TSH-stimulated mouse thyroids in the perifusion system.
We established a perifusion system using mouse thyroid glands. In this system, TSH increased the release of T3 and T4 significantly, and the response of thyroglobulin to TSH was delayed in comparison with that of T3 and T4.
Second Department of Internal Medicine, Osaka University Medical School, Japan.
M
M
Mori
K
K
Tajima
J
J
Miyagawa
M
M
Shimizu
K
K
Mashita
S
S
Sugihara
T
T
Hamaoka
H
H
Fujiwara
S
S
Tarui
D000818:Animals; D051379:Mice; D010477:Perfusion; D013954:Thyroglobulin / Q000378:metabolism*; D013961:Thyroid Gland / Q000033:anatomy & histology / Q000187:drug effects / Q000378:metabolism*; D013972:Thyrotropin / Q000494:pharmacology*; D013974:Thyroxine / Q000378:metabolism*; D013997:Time Factors; D014284:Triiodothyronine / Q000378:metabolism*
D014284:Triiodothyronine; D013972:Thyrotropin; D013954:Thyroglobulin; D013974:Thyroxine