Novel phospholipids with aliphatic dicarboxylic acid residues in a lipid extract from bovine brain.
A vasodepressor phospholipid fraction purified from a lipid extract of bovine brain was found to contain novel phospholipids with both a long-chain acyl group and an aliphatic dicarboxylic acid residue. This was shown by analyzing the fraction as tert-butyldimethylsilyl derivatives of glyceride by capillary GC-MS after hydrolysis with phospholipase C. Six molecular species with a palmitoyl group and an aliphatic dicarboxylate (chain length C4-C9), and two species with both a stearoyl group and a succinate or glutarate residue were detected.
Faculty of Pharmaceutical Sciences, University of Tokushima, Japan.
A
A
Tokumura
T
T
Asai
K
K
Takauchi
K
K
Kamiyasu
T
T
Ogawa
H
H
Tsukatani
D000818:Animals; D001923:Brain Chemistry; D002417:Cattle; D008401:Gas Chromatography-Mass Spectrometry; D010743:Phospholipids / Q000032:analysis*; D010738:Type C Phospholipases / Q000378:metabolism
D010743:Phospholipids; D010738:Type C Phospholipases