Taurine efflux from brain slices: potassium-evoked release is greater from immature than mature brain tissue.
The stimulated release of taurine was severalfold greater from slices of immature than mature brain. The release had a strikingly slow time course at all ages, the slower the younger were the animals. It is concluded that taurine is an important regulatory of neuronal activity in the developing brain.
Department of Biomedical Sciences, University of Tampere, Finland.
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D000375:Aging; D000596:Amino Acids / Q000494:pharmacology; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000254:growth & development* / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D051379:Mice; D008815:Mice, Inbred Strains; D011188:Potassium / Q000494:pharmacology*; D013654:Taurine / Q000378:metabolism*; D014316:Tritium
D000596:Amino Acids; D014316:Tritium; D013654:Taurine; D011188:Potassium