Clinical use of Ga-67 DFO-DAS-fibrinogen.
The clinical usefulness of 67Ga-DFO-DAS-fibrinogen, a newly developed thrombus imaging agent, was evaluated. Fifteen cases were given 2 mCi of 67Ga-DFO-DAS-fibrinogen and images were obtained up to 96 hours after injection. Abnormal accumulation of 67Ga-DFO-DAS-fibrinogen was imaged in seven cases with either venous or arterial thrombi, and no side effects were noted. These results suggested that 67Ga-DFO-DAS-fibrinogen might be a promising agent for thrombus imaging.
Department of Radiology and Nuclear Medicine, Faculty of Medicine, Kyoto University, Japan.
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Yamamoto
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Torizuka
D000328:Adult; D000368:Aged; D003676:Deferoxamine; D005260:Female; D005340:Fibrinogen; D005710:Gallium Radioisotopes; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013213:Starch / Q000031:analogs & derivatives; D013924:Thrombophlebitis / Q000000981:diagnostic imaging; D013927:Thrombosis / Q000000981:diagnostic imaging*
D005710:Gallium Radioisotopes; D005340:Fibrinogen; D013213:Starch; C012880:dialdehyde starch; D003676:Deferoxamine