Kaposi's sarcoma in a young man in absence of AIDS or other known causes of immune suppression.
Kaposi's Sarcoma (KS) in young individuals is unusual and most often associated with cellular immunodeficiency caused by infective or other neoplastic diseases. It has recently been highly associated with the Acquired Immunodeficiency Syndrome (AIDS). We report the case of a heterosexual 29 year aged man with no evidence of underlying malignancy or infectious diseases. Antibodies to the Human Immunodeficiency Virus (HIV) were absent on repeat testing. His immunological profile demonstrated elevated number of CD8+ cells, normal number of CD3+ and CD4+ cells and hypogammaglobulinemia. These data are distinctly different from those described with AIDS associated KS. The development of KS in young individuals of mediterranean origin may reflect mild degree of immune abnormalities in the absence of infection with HIV.
Divisione di Dermatologia, Spedali Civili di Brescia, Italy.
P
P
Calzavara-Pinton
R
R
Cattaneo
F
F
Franceschini
P
P
Airò
D000328:Adult; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count; D008214:Lymphocytes / Q000145:classification / Q000276:immunology; D008297:Male; D012514:Sarcoma, Kaposi / Q000276:immunology*; D012878:Skin Neoplasms / Q000276:immunology*
D007136:Immunoglobulins