[Endocrine changes in children with acute viral hepatitis].
The paper is concerned with the results of hormonal studies on virus hepatitis in 84 children aged 2 to 14, of them 28 had a mild form of disease, 50--medium grave and 6--a severe form of disease. A study was made of the blood content of ACTH, STH, TSH, cortisol, aldosterone, T3, T4, prolactin, and alpha-fetoprotein. The hormones were determined by a radioimmunoassay using Sorin kits (France). A considerable increase in the blood content of ACTH, cortisol, aldosterone and a moderate increase in STH, TSH and T4 concentrations were noted at the height of virus hepatitis. The above changes were interpreted as a result of combined manifestation of a stress reaction and a decrease in the catabolism of some liver hormones. An assumption has been made of a possibility of the effect of late hormonal shifts on the outcome of virus hepatitis of development of chronic hepatitis.
V M
VM
Dil'man
N I
NI
Nisevich
I I
II
Zubikova
A A
AA
Romaniukha
T P
TP
Moleva
D000208:Acute Disease; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006525:Hepatitis, Viral, Human / Q000097:blood*; D006801:Humans; D010908:Pituitary Hormones, Anterior / Q000097:blood*; D013963:Thyroid Hormones / Q000097:blood*
D000305:Adrenal Cortex Hormones; D010908:Pituitary Hormones, Anterior; D013963:Thyroid Hormones
Endokrinnye sdvigi u deteĭ s ostrym virusnym gepatitom.