[Clinical picture and treatment of acute respiratory poisoning by balagrin].
Group respiratory intoxication with balagrin (a pesticide from the nitroanilide group) in 3 agricultural female workers is described. Such group intoxication has not been described up to 1984. The clinical course is manifested by two syndromes: cerebrotoxic--which is the leading syndrome and includes headache, vertigo, adynamia, weakness, EEG changes; upper dyspeptic--which is a secondary syndrome and includes epigastric pain, nauseous, vomiting, anorexia. By X-ray examination a third syndrome--pulmonotoxic--has been registered without any other respiratory manifestations. It is probably due to venous stasis and peribronchial interstitial changes. The treatment with glucose infusions, vit. B6, vit C and cerucal could not fully abolish the cerebral manifestations. This led to, a prolonged treatment with cerebroprotective drugs (Pyramem, vitamin B complex). The 8-month observation showed a slow reverse evolution of the subjective complaints and the objective findings. It is concluded that the pesticide balagrin exerts marked toxic action under certain conditions.
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Tashev
D000208:Acute Disease; D000328:Adult; D000336:Aerosols; D000382:Agricultural Workers' Diseases / Q000139:chemically induced* / Q000188:drug therapy; D000931:Antidotes / Q000627:therapeutic use; D001927:Brain Diseases / Q000139:chemically induced / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced* / Q000188:drug therapy; D008875:Middle Aged; D013577:Syndrome; D014052:Toluidines / Q000506:poisoning*; D014992:Xylenes / Q000506:poisoning*
D000336:Aerosols; D000931:Antidotes; D014052:Toluidines; D014992:Xylenes; C020220:balagrin
Vŭrkhu klinikata i lechenieto na ostrite respiratorni intoksikatsii s balagrin.