Left atrial mass 16 years after radiation therapy for mediastinal neuroblastoma.
Tumors involving the heart during childhood are rare. However, neuroblastoma, a common pediatric malignancy, has been described to involve the cardiovascular system in 3%-12% of patients dying with this tumor. Rarely is such involvement diagnosed ante mortem and never, to our knowledge, has a benign cardiac tumor been reported to present in childhood after successful eradication of neuroblastoma. We describe the identification and surgical resection of a nodular, hypertrophied, calcified, pedunculated left atrial mass in a 16-year-old boy who was complaining of exercise-associated presyncope and headaches 16 years after irradiation and chemotherapy for mediastinal neuroblastoma.
Department of Pediatrics, Mayo Clinic, Rochester, Minnesota 55905.
G J
GJ
Ensing
D J
DJ
Driscoll
W A
WA
Smithson
D000293:Adolescent; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D006338:Heart Neoplasms / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008479:Mediastinal Neoplasms / Q000628:therapy; D009378:Neoplasms, Multiple Primary; D009447:Neuroblastoma / Q000628:therapy; D010494:Pericarditis, Constrictive / Q000209:etiology
D003037:Cobalt Radioisotopes; D003520:Cyclophosphamide