Pathology and pathogenicity of Eimeria scabra (Henry, 1931) in experimentally infected pigs.
Pathology and pathogenicity of the coccidium Eimeria scabra were studied in pigs experimentally infected at 1-2 months of age. Two phases were evident in the course of pathogenic process. In the first phase, 7-8 days after inoculation (DAI), caudal jejunum and ileum were affected by a severe catarrhal inflammation characterized by intensive infiltrate containing numerous neutrophils and eosinophils, vigorous activation of Peyer's patches, villous fusion and general atrophy of epithelium. In the second phase, 9 DAI, release of immature oocysts was associated with break-down of the epithelial barrier and development of pseudomembranes. Reparative and regenerative processes followed immediately, and 13 DAI, the structure of caudal jejunum and ileum was completely reestablished.
Vítovec
J
J
Institute of Parasitology, Laboratory of Electron Microscopy, Czechoslovak Academy of Sciences, Ceské Budĕjovice.
Koudela
B
B
Stĕrba
J
J
D000818:Animals; D003048:Coccidiosis / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D004539:Eimeria / Q000472:pathogenicity*; D004848:Epithelium / Q000473:pathology / Q000648:ultrastructure; D007082:Ileum / Q000473:pathology* / Q000648:ultrastructure; D007413:Intestinal Mucosa / Q000473:pathology / Q000648:ultrastructure; D007583:Jejunum / Q000473:pathology* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D013552:Swine; D013553:Swine Diseases / Q000469:parasitology / Q000473:pathology*