Principal axis analysis of gene frequency data.
When a set of populations are compared in respect of gene frequencies, and the chi-square test of heterogeneity is found to be significant, it is pertinent to find out whether the heterogeneity can be explained by a few linear combinations of the gene frequencies, and the total heterogeneity chi-square value can be partitioned as the sum of heterogeneity chi-square values contributed by the linear combinations. The present report describes such a method, and the linear combination that explains the maximum heterogeneity is called the principal axis. An application of this method is presented to find clusters of 31 Mongoloid tribal populations of eastern India using ABO gene frequency data.
Department of Biostatistics, University of Pittsburgh, Pennsylvania 15261.
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Majumder
D000017:ABO Blood-Group System / Q000235:genetics*; D044466:Asian People; D005787:Gene Frequency; D006801:Humans; D007194:India
D000017:ABO Blood-Group System