Comparison of the cortisol suppression index and the DST within major depressive disorder.
The authors compared the Cortisol Suppression Index (CSI) and raw postdexamethasone cortisol values for their usefulness in detecting endogeneity and severity in major depressive disorder (MDD). The 8 AM postdexamethasone cortisol provided the best correlation with both endogeneity and severity. The CSI does not appear to be a satisfactory alternative to the current DST for this purpose.
Department of Psychiatry and Behavioral Sciences, Stanford University, California.
H A
HA
Whiteford
C A
CA
Peabody
P A
PA
Berger
D000328:Adult; D000368:Aged; D003866:Depressive Disorder / Q000175:diagnosis*; D003907:Dexamethasone; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged
D003907:Dexamethasone; D006854:Hydrocortisone