Diabetes insipidus and pregnancy.
A case of a pregnant woman with diabetes insipidus is reported. The course of the pregnancy was uneventful except for a slightly increased need for vasopressin during the last trimester. Neurophysin levels increased at a rate similar to that seen in the normal pregnant state. The combination of normal neurophysin physiology and undisturbed spontaneous labor demonstrating normal oxytocin secretion suggests that there is a singular deficiency of antidiuretic hormone in essential diabetes insipidus.
Department of Internal Medicine, University Hospital, University of Gent, Belgium.
R
R
Rubens
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M
Thiery
D000328:Adult; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use; D003919:Diabetes Insipidus / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D004231:Diuresis; D005260:Female; D006801:Humans; D009481:Neurophysins / Q000097:blood; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D014667:Vasopressins / Q000097:blood
D009481:Neurophysins; D014667:Vasopressins; D003894:Deamino Arginine Vasopressin