Inactivation of Legionella pneumophila by hypochlorite and an organic chloramine.
The susceptibility of a strain of Legionella pneumophila to disinfection by an organic halamine, free chlorine, and a mixture of the organic halamine and free chlorine was assessed. The organic halamine was found to have superior stability in solution and to exhibit adequate disinfectant potential over a period of 1 month of repeated reinoculations of fresh bacteria. The combined halamine exhibited great potential for use in maintaining closed-cycle cooling water systems free of L. pneumophila.
Department of Microbiology, College of Veterinary Medicine, Auburn, Alabama.
L J
LJ
Swango
G R
GR
Wilt
A D
AD
Killen
D E
DE
Williams
S D
SD
Worley
D002118:Calcium / Q000494:pharmacology*; D017610:Calcium Compounds; D004202:Disinfectants / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007875:Legionella / Q000187:drug effects* / Q000254:growth & development; D010080:Oxazoles / Q000494:pharmacology*; D023303:Oxazolidinones; D013696:Temperature; D013997:Time Factors; D014871:Water Microbiology; D014881:Water Supply
D017610:Calcium Compounds; D004202:Disinfectants; D010080:Oxazoles; D023303:Oxazolidinones; C004488:calcium hypochlorite; C036350:3-chloro-4,4-dimethyl-2-oxazolidinone; D002118:Calcium