Effect of prenatal and/or neonatal diethylstilbestrol (DES) or allylestrenol (AE) treatment on the postnatal development of the chicken ovary.
Chickens treated with allylestrenol or diethylstilbestrol in the egg on 9th day of incubation, or one day after hatching, or on both occasions, equally showed histomorphological indications of a distinct ovarian activation at 5 days of age, which was most pronounced in the twice-treated birds. A single steroid exposure at one day of age accounted for inhibition of ovarian activity at 6 weeks, presumably owing to a long-term effect on the hypothalamo-hypophyseal system, which begins to function from the 12th day of incubation.
Department of Biology, Semmelweis University Medical School, Budapest, Hungary.
P T
PT
Sótonyi
G
G
Csaba
D000500:Allylestrenol / Q000494:pharmacology*; D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D004054:Diethylstilbestrol / Q000494:pharmacology*; D004963:Estrenes / Q000494:pharmacology*; D005260:Female; D010053:Ovary / Q000187:drug effects / Q000196:embryology / Q000254:growth & development*; D013997:Time Factors
D004963:Estrenes; D004054:Diethylstilbestrol; D000500:Allylestrenol