The one-and-a-half syndrome. Clinical correlation with a pontine lesion demonstrated by nuclear magnetic resonance imaging in a case of multiple sclerosis.
Nuclear magnetic resonance (NMR) imaging has been used to visualise a localised area of demyelination in the dorsal pons of a patient who presented with an unusual disorder of eye movements, namely, the one-and-a-half syndrome. Judged clinically the patient made a nearly complete recovery, but little change was apparent in the NMR image six months later.
University Department of Medicine, Royal Infirmary, Edinburgh.
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Martyn
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Kean
D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D003711:Demyelinating Diseases / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000150:complications*; D009886:Ophthalmoplegia / Q000209:etiology*; D011149:Pons / Q000473:pathology*; D013577:Syndrome