Absorption of glucose from the intestine following experimental scald injury in rats.
Experiments in vivo showed that absorption of glucose from the small intestine of rats was measurably decreased following scald injury. This phenomenon is probably secondary to other disturbances in metabolism, since the capacity of the intestine to transport glucose was not impaired when measured in vitro, Factors influencing the decreased capacity observed in vivo include disturbances in electrolyte metabolism and the hyperglycaemia produced as a result of the injury. The impaired capacity of the intestine to transport glucose in vivo could be partially restored to normal by administration of the mineralacorticoid deoxycorticosterone acetate, infusion with normal saline or the administration of insulin. The influences of alterations in mineral and glucose metabolism were confirmed by demonstrating an impairment of transport capacity in vivo in uninjured and adrenalectomized, or alloxan diabetic rats.
Department of Physiology, First Military Medical College, Mei Hua Yuan, Guangzhou, PR China.
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Yü
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D000311:Adrenal Glands / Q000502:physiology; D000315:Adrenalectomy; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002056:Burns / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism; D008297:Male; D051381:Rats; D014882:Water-Electrolyte Balance
D000469:Alkaline Phosphatase; D005947:Glucose