The role of reactive metabolites in drug-induced teratogenesis.
Hales
B F
BF
Department of Pharmacology & Therapeutics, McGill University, Montreal, Quebec.
Slott
V L
VL
D000171:Acrolein / Q000378:metabolism / Q000633:toxicity*; D000447:Aldehydes / Q000633:toxicity*; D000818:Animals; D001711:Biotransformation; D003520:Cyclophosphamide / Q000378:metabolism / Q000633:toxicity*; D004622:Embryo, Mammalian / Q000187:drug effects* / Q000378:metabolism; D009924:Organ Culture Techniques; D010752:Phosphoramide Mustards / Q000378:metabolism / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity; D013723:Teratogens
D000447:Aldehydes; D010752:Phosphoramide Mustards; D013723:Teratogens; D000171:Acrolein; D003520:Cyclophosphamide