Gene conversion in avian mesotocin and vasotocin genes: a recurrent mechanism linking two neurohypophysial precursor lineages?
Amino acid sequences of the first half of MSEL- and VLDV-neurophysins from goose and chicken have been determined. Identical substitutions in positions 17, 18, 35, 36 and 41 of both neurophysins of a given species when compared with their mammalian counterparts suggest a gene conversion between vasotocin--MSEL-neurophysin and mesotocin--VLDV-neurophysin genes. This event, which has already been observed for three mammalian species, seems recurrent and would link the evolution of the two neurohypophysial hormone precursors.
Laboratory of Biological Chemistry, University of Paris VI, France.
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B
Lévy
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G
Michel
J
J
Chauvet
M T
MT
Chauvet
R
R
Acher
D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D002645:Chickens; D005777:Geese; D005785:Gene Conversion; D008040:Genetic Linkage; D008969:Molecular Sequence Data; D009481:Neurophysins / Q000235:genetics; D010121:Oxytocin / Q000031:analogs & derivatives* / Q000235:genetics; D014668:Vasotocin / Q000235:genetics*
D009481:Neurophysins; C001713:mesotocin; D010121:Oxytocin; D014668:Vasotocin