Vasopressin-resistant diabetes insipidus, liver dysfunction, hyperuricemia and decreased renal function. A case report.
A case of transient nephrogenic diabetes insipidus occurred in late pregnancy, the first associated with biopsy-proven hepatitis. Five previously reported cases occurred in pregnancy. All six patients demonstrated similar but transient signs, symptoms and laboratory abnormalities suggesting a syndrome peculiar to pregnancy. The characteristics of this syndrome are elevated liver function studies, decreased renal function, hyperuricemia and transient vasopressin-resistant diabetes insipidus.
Department of Obstetrics and Gynecology, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27103.
M
M
Harper
C G
CG
Hatjis
R G
RG
Appel
W E
WE
Austin
D000328:Adult; D003919:Diabetes Insipidus / Q000150:complications* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006505:Hepatitis / Q000209:etiology*; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications; D011263:Pregnancy Trimester, Third; D014527:Uric Acid / Q000097:blood*; D014667:Vasopressins / Q000502:physiology*; D014882:Water-Electrolyte Balance
D014667:Vasopressins; D014527:Uric Acid