Adh expression in species of the mulleri subgroup of Drosophila.
The locus encoding the NAD-dependent alcohol dehydrogenase (alcohol:NAD oxidoreductase; EC 1.1.1.1) is duplicated in some species of the cactophilic mulleri subgroup of Drosophila. Here we report a survey on the expression throughout development and in different tissues for this system, its regulation using interspecific hybrids, and the effects induced by 2-propanol in 10 species belonging to four different clusters of the above-mentioned subgroup. Our results indicate different expression throughout development and in different tissues, cis regulation in hybrid ovaries, trans (-) regulation in hybrid adults, and different responses to 2-propanol.
Departament de Genetica i Microbiologia, Universitat Autonoma de Barcelona, Spain.
J
J
Alberola
A
A
Sanchez
A
A
Fontdevila
D000433:1-Propanol / Q000494:pharmacology; D000426:Alcohol Dehydrogenase / Q000235:genetics*; D000818:Animals; D004330:Drosophila / Q000235:genetics*; D005786:Gene Expression Regulation
D000433:1-Propanol; D000426:Alcohol Dehydrogenase