Prostate gland and epididymis phosphatase isoenzymes: comparisons of young adult and aged rats.
Relative activities of acid and alkaline phosphatases in rat reproductive tissue were studied in young adult (10-12 months) and aged (30-34 months) rats. Prostatic alkaline phosphatase alone increased in aged animals. Moreover, prostate preparations contain two isoenzymes of alkaline phosphatase whereas only one was found in epididymal tissues. Age-associated changes in the prostatic alkaline phosphatase isoenzyme ratios were observed. No significant age-related changes in acid phosphatase tartrate sensitivity were found. Techniques for the preparation of prostate and epididymis tissue extracts are reported.
Department of Biology, Boston University, Mass.
G J
GJ
Hinkle
D000135:Acid Phosphatase / Q000378:metabolism; D000375:Aging; D000469:Alkaline Phosphatase / Q000378:metabolism; D000535:Aluminum / Q000494:pharmacology; D000818:Animals; D003402:Creatine Kinase / Q000378:metabolism; D004822:Epididymis / Q000201:enzymology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism*; D008297:Male; D011467:Prostate / Q000201:enzymology*; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains; D013644:Tartrates / Q000494:pharmacology
D007527:Isoenzymes; D013644:Tartrates; D000535:Aluminum; D005954:Glucosephosphate Dehydrogenase; D003402:Creatine Kinase; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; C029768:tartaric acid