Ibuprofen is a useful treatment for primary dysmenorrhoea.
A double-blind crossover placebo-controlled trial over 6 cycles in 38 Australian women has confirmed that ibuprofen is a valuable drug for the treatment of primary spasmodic dysmenorrhoea. This drug was highly effective when given in a dosage of one 400mg tablet at the first sign of pain or bleeding followed by further 400mg tablets every 4 to 6 hours for the duration of expected symptoms. Side-effects were mild and noted with equal low frequency during placebo treatment.
Fraser
I S
IS
Department of Obstetrics and Gynaecology, University of Sydney.
McCarron
G
G
D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D004412:Dysmenorrhea / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D008875:Middle Aged; D011448:Prostaglandin Antagonists / Q000627:therapeutic use*; D011897:Random Allocation
D011448:Prostaglandin Antagonists; D007052:Ibuprofen