Sample size determination in studies with matched pairs.
Two modifications are made in Schlesselman's procedure for determining the total number of pairs to be studied in a case-control study with matching. One is to take account of the use of the continuity correction in the McNemar test statistic, and the other is to incorporate a measure of the degree of association induced by the matching variables between a case's exposure status and that of his or her matched control. The result of both modifications is to increase the required number of pairs above the number produced by Schlesselman's procedure.
Division of Biostatistics, Columbia University School of Public Health, New York, NY 10032.
J L
JL
Fleiss
B
B
Levin
D004812:Epidemiologic Methods; D011336:Probability; D012494:Sampling Studies