A study of additional forms of the human sperm lactate dehydrogenase isoenzyme.
Unusual isoenzymes of the sperm-specific lactate dehydrogenase detected in the seminal plasma of some infertile men were investigated using selective precipitation by antisera followed by electrophoretic resolution. The presence of two C subunit types was established: type I is a polymer of the four common C-subunits and type II consists of four C-subunits. Subunits of types I and II combine to form 5 sperm-specific binomially distributed lactate dehydrogenase isoenzymes. These results suggest the existence of two alleles at the c locus.
Vuk Vrhovac Institute of Diabetes, Endocrinology and Metabolic Diseases, Medical School, University of Zagreb, Yugoslavia.
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Gavella
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Lipovac
D004591:Electrophoresis, Polyacrylamide Gel; D006358:Hot Temperature; D006801:Humans; D007248:Infertility, Male / Q000201:enzymology; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D008297:Male; D012661:Semen / Q000201:enzymology; D013094:Spermatozoa / Q000201:enzymology*; D013997:Time Factors
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase