[Clinical and etiopathogenetic aspects of lissencephaly type II syndrome].
Two cases of lissencephaly syndrome type II are reported. Lissencephaly (smooth brain) is caused by a disorder of neuronal migration resulting in connatal hydrocephalus and lack of gyri as well as developmental abnormalities of the eye and muscles. Embryological relationships between these malformations and clinical appearances are described.
Universitäts-Kinderklinik Bonn.
R
R
Mielke
J H
JH
Lu
G
G
Kochs
S
S
Kowalewski
D000015:Abnormalities, Multiple / Q000235:genetics*; D001921:Brain / Q000002:abnormalities*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000235:genetics; D007231:Infant, Newborn; D008607:Intellectual Disability / Q000235:genetics; D009123:Muscle Hypotonia / Q000235:genetics; D013577:Syndrome
Klinische und ätiopathogenetische Aspekte des Lissenzephalie-Syndroms Typ II.