Preparation of a series of 9-alkylaminoacridines and 9-imino-10-alkylacridines and their binding to desoxyribonucleic acid.
The preparation, separation and identification of a series of 9-alkylaminoacridines and 9-imino-10-alkylacridines is described. Their binding to desoxyribonucleic acid which has been investigated by a number of spectroscopic techniques is reported.
Groupe d'Etude et des Recherches en Chimie Thérapeutique Organic et Physique, Faculté de Pharmacie, Marseille, France.
A M
AM
Galy
J P
JP
Galy
J
J
Barbe
D
D
Sharples
D000166:Acridines / Q000138:chemical synthesis* / Q000378:metabolism; D000609:Aminoacridines / Q000138:chemical synthesis* / Q000378:metabolism; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004247:DNA / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism
D000166:Acridines; D000609:Aminoacridines; D004247:DNA