Configurational entropy of native proteins.
Simulations of the residual configurational entropy of a protein in the native state suggest that it is nearly an order of magnitude larger than the entropy of denaturation. The implications of this result are discussed.
Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138.
M
M
Karplus
T
T
Ichiye
B M
BM
Pettitt
D008433:Mathematics; D011487:Protein Conformation; D011506:Proteins; D013816:Thermodynamics
D011506:Proteins