[Intracerebral granuloma with serum anti-human ascaris antibody: case report].
A 1.5-year-old girl with a convulsion attack due to intracerebral granuloma in the right frontal lobe is reported. Her serum was positive with anti-human ascaris antibody, although no ova of the parasites were detected in the feces. She had grown up intimately with several cats in the home. These findings suggested that the granuloma was due to larva migrans of toxocara, which cross-reacts immunologically with human ascaris. Histological examination of the granuloma revealed no eosinophilic infiltration. No systemic reactions such as eosinophilia and hepatomegaly were found except for elevation of protein in cerebrospinal fluid. These were similar to those of ocular type of toxocara larva migrans.
Department of Neurosurgery, Sagamihara National Hospital, Kanagawa, Japan.
T
T
Taira
T
T
Beppu
K
K
Matsumori
O
O
Kubo
D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis*; D001200:Ascaris / Q000276:immunology*; D001927:Brain Diseases / Q000276:immunology / Q000469:parasitology* / Q000473:pathology; D003429:Cross Reactions; D005260:Female; D006099:Granuloma / Q000276:immunology / Q000469:parasitology* / Q000473:pathology; D006801:Humans; D007223:Infant; D007815:Larva Migrans / Q000276:immunology; D014119:Toxocara / Q000276:immunology
D000909:Antibodies, Helminth