[Natural killer activity of splenocytes of C3HA mice in the early period after transplantation of hepatoma 22a cells].
It is shown that during 10 days after transplantation of syngenic 22a hepatoma cells to C3HA mice, wave-like fluctuations of the natural killer cell (NK) activity of splenocytes take place. Xenogenic (K-562) and allogenic (AC-1) cells are used as target cells in the 18th hour 3H-uridine cytotoxic test. A significant increase in the NK-activity on the 2nd-3rd and 7-9th days after tumour cells transplantation is observed. Elimination of adherent cells from suspension of splenocytes lead to an increase in the NK-activity especially on the 7th-9th days.
Filatova
N A
NA
Malygin
A M
AM
Pleskach
V A
VA
Fel'
V Ia
VIa
D000818:Animals; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D007694:Killer Cells, Natural / Q000276:immunology*; D008114:Liver Neoplasms, Experimental / Q000276:immunology* / Q000473:pathology; D051379:Mice; D008809:Mice, Inbred C3H; D009368:Neoplasm Transplantation; D013154:Spleen / Q000276:immunology*; D013997:Time Factors
Estestvennaia killernaia aktivnost' splenotsitov mysheĭ linii C3HA v rannie sroki posle transplantatsii kletok gepatomy 22a.