Hypertension in a child with type IA glycogen storage disease.
Hypertension and proteinuria were observed in a 2-year-old child with type IA (von Gierke's) glycogen storage disease (GSD). She had evidence of hyperfiltration and had elevated selective renal vein renins. On renal biopsy, increased mesangial cell matrix and cellularity were observed with focal thickening and irregularity of the basement membrane. This case may be representative of the early renal findings in type IA GSD.
Department of Pediatrics, University of Texas Medical School, Houston 77030.
A J
AJ
Jonas
R R
RR
Verani
R R
RR
Howell
S B
SB
Conley
D005260:Female; D006003:Glycogen / Q000032:analysis; D005953:Glycogen Storage Disease Type I / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology* / Q000473:pathology; D007223:Infant; D007668:Kidney / Q000032:analysis / Q000648:ultrastructure; D007674:Kidney Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D011507:Proteinuria
D006003:Glycogen