Intranuclear distribution of the non-histone proteins: evidence for their compartmentalization.
1. Qualitative and quantitative distribution of the non-histone proteins in nuclear matrix, chromatin, a new type of RNP-network and nucleosol of Friend cells have been investigated. 2. The specific territorial distribution and metabolism of these proteins found support for the idea of their exact compartmentalization. 3. Since the majority of the non-histone proteins belong to the protein moiety of nuclear RNP-structures their specific territorial distribution probably express a primary compartmentalization of the nuclear ribonucleoproteins.
Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
N
N
Yancheva
E
E
Ivanova
L
L
Djondjurov
D000818:Animals; D002460:Cell Line; D002467:Cell Nucleus / Q000032:analysis* / Q000648:ultrastructure; D002868:Chromosomal Proteins, Non-Histone / Q000032:analysis*; D004247:DNA / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D008854:Microscopy, Electron; D008970:Molecular Weight; D012261:Ribonucleoproteins / Q000032:analysis
D002868:Chromosomal Proteins, Non-Histone; D012261:Ribonucleoproteins; D004247:DNA