Assessment of neutrophil migration, phagocytosis and bactericidal capacity in neonatal foals.
Comparison of neutrophil function was made between 8 clinically normal pony foals (3 to 7 days of age), and their dams. Random migration, stimulated migration to zymosan-activated serum, bacterial phagocytosis and bactericidal capacity of neutrophils were determined in vitro. Random migration was greater (P less than 0.01) and stimulated migration was less (P less than 0.01) in foals than in their dams. Bacterial phagocytosis and bactericidal capacity of neutrophils were not different (P greater than 0.05) between foals and mares. Results of this study suggested that neonatal foals have altered neutrophil locomotion, when compared to their dams.
Department of Clinical Studies, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
D D
DD
Morris
G
G
Gaulin
P J
PJ
Strzemienski
P
P
Spencer
D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D002464:Cell Migration Inhibition; D002465:Cell Movement; D005260:Female; D006736:Horses / Q000276:immunology*; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis; D013211:Staphylococcus aureus / Q000276:immunology