The effect of valvulotomy on the flow rate through the saphenous vein graft: clinical implications.
Potential differences in flow rates between reversed and in situ saphenous vein bypass grafts were evaluated. One hundred ten greater saphenous vein segments containing isolated valves were examined with fiber-optic angioscopy during pulsatile and nonpulsatile flow. Valve competency was determined, and the degree of luminal obstruction caused by the valve during reversed flow was calculated with caliper measurements of the video image. Flow measurements were obtained before and after valvulotomy, in reversed and nonreversed vein orientations. Increased flow rates occurred during pulsatile irrigation only, after valvulotomy in vein segments with diameters less than 2.5 mm (p less than 0.001, Bonferroni t test). In these small-diameter vein segments, the flow rate in reversed valve-intact vein was 94.4 +/- 28.9 ml/min (mean +/- 1 standard deviation), the flow rate in reversed valve-disrupted vein was 136.4 +/- 36.5 ml/min, and the flow rate in nonreversed valve-disrupted vein was 137.8 +/- 31.3 ml/min. In 22 vein segments, luminal obstruction caused by the intact valve was measured angioscopically. A small valve orifice was found to be related to a large increase in flow rate after valvulotomy (p less than 0.02, least-squares regression). In addition, veins with diameters less than 2.5 mm have significantly smaller valve orifices compared with veins with diameters greater than 2.5 mm. These results present important clinical implications as the number of distal extremity reconstructions increases.
Department of Surgery, Sequoia Hospital.
A K
AK
Chin
D N
DN
Mayer
R K
RK
Goldman
J A
JA
Lerman
C
C
Olcott
T J
TJ
Fogarty
D001783:Blood Flow Velocity; D004724:Endoscopy; D005069:Evaluation Studies as Topic; D006083:Graft Occlusion, Vascular / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology; D011673:Pulsatile Flow; D012039:Regional Blood Flow; D012501:Saphenous Vein / Q000033:anatomy & histology / Q000502:physiology* / Q000503:physiopathology / Q000601:surgery / Q000637:transplantation