Liver tumours and muscle relaxants. Electromyographic studies in children.
Electromyographic studies of the onset of action of tubocurarine or alcuronium were performed on eight occasions in five patients who had liver masses. There was a slow onset of action and an increased dose requirement in those with malignant disease. Normal responses were found in a patient with benign nodular hyperplasia and in another where the malignant tumour was successfully treated with chemotherapy.
Royal Children's Hospital, Parkville, Victoria, Australia.
T C
TC
Brown
M
M
Gregory
B
B
Bell
P C
PC
Campbell
D000443:Alcuronium / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D004351:Drug Resistance; D004576:Electromyography; D006801:Humans; D008113:Liver Neoplasms / Q000503:physiopathology*; D009119:Muscle Contraction / Q000187:drug effects*; D009126:Muscle Relaxation / Q000187:drug effects*; D013997:Time Factors; D014117:Toxiferine / Q000031:analogs & derivatives*; D014403:Tubocurarine / Q000494:pharmacology*
D014117:Toxiferine; D000443:Alcuronium; D014403:Tubocurarine