Differential effects of ethanol on photic and acoustic evoked potentials in the reticular formation of rats.
Flash and click evoked potentials were recorded from the same electrode in the midbrain reticular formation of hooded rats. Animals were given i.p. injections of saline, 0.25, 0.5, 1.0 or 2.0 g ethanol/kg body wt. on separate days. The click data demonstrated both a biphasic effect of ethanol and an enhanced sensitivity relative to the flash data. It is suggested that differing evoking stimuli may sample the activity of functionally different populations of neurons within the reticular formation.
Hetzler
B E
BE
Department of Psychology, Lawrence University, Appleton, Wisconsin 54912.
Drake
C T
CT
McLarty
L J
LJ
D000818:Animals; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000494:pharmacology*; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D005074:Evoked Potentials, Visual / Q000187:drug effects*; D008297:Male; D051381:Rats; D012154:Reticular Formation / Q000187:drug effects*
D000431:Ethanol