Adipose tissue fatty acids and blood pressure in middle-aged men from southern Italy.
Adipose tissue (AT) biopsies were performed in a random population sample of 74 clinically healthy middle-aged men (40-49 years) from southern Italy. The percentage of saturated fatty acids (FA) in AT was directly correlated with systolic (SBP) and diastolic (DBP) blood pressure (p less than 0.01). This relationship was independent of smoking habit and body weight. AT of men in the upper DBP quintile (range 90-102 mmHg) was significantly richer in palmitic acid (p less than 0.01) compared to that of men in the lowest DBP quintile. Dietary history demonstrated that the overall intake of saturated fat (% energy) was similar in the two extreme DBP quintiles. There was a relatively higher consumption of fish by those in the lowest DBP quintile (p less than 0.05). The amount of monounsaturated fat consumed (% energy) was also higher (p less than 0.05) in men with low blood pressure. Men in the upper quintile of DBP consumed more eggs (p less than 0.05).
Institute of Internal medicine and Metabolic Disease, Clinica Medica, University of Naples, Italy.
P
P
Rubba
M
M
Mancini
F
F
Fidanza
G
G
Gautiero
M
M
Salo
T
T
Nikkari
R
R
Elton
M F
MF
Oliver
D000273:Adipose Tissue / Q000032:analysis*; D000328:Adult; D001794:Blood Pressure; D002784:Cholesterol / Q000097:blood; D004041:Dietary Fats / Q000009:adverse effects; D005227:Fatty Acids / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D014280:Triglycerides / Q000097:blood
D004041:Dietary Fats; D005227:Fatty Acids; D014280:Triglycerides; D002784:Cholesterol