Cerebrospinal fluid choline, and acetylcholinesterase activity in familial vs. non-familial Alzheimer's disease patients.
Acetylcholinesterase (AChE) and choline (Ch) in the cerebrospinal fluid (CSF) from familial and non-familial Alzheimer disease patients were studied. The choline level was significantly less (p less than 0.04) in familial patients than in non-familial patients. However, there was no difference in AChE activity in these two groups.
Kumar
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V
Department of Psychiatry, Southern Illinois University School of Medicine, Springfield 62708.
Giacobini
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E
D000110:Acetylcholinesterase / Q000134:cerebrospinal fluid*; D000368:Aged; D000381:Agraphia / Q000134:cerebrospinal fluid / Q000201:enzymology; D000544:Alzheimer Disease / Q000134:cerebrospinal fluid* / Q000201:enzymology / Q000235:genetics; D002794:Choline / Q000134:cerebrospinal fluid*; D006801:Humans; D008875:Middle Aged
D000110:Acetylcholinesterase; D002794:Choline