Effect of intravitreal liquid silicone on optic nerve function.
We recorded visual-evoked cortical potentials before and after pars plana vitrectomy and intravitreal liquid silicone filling in 30 patients (30 eyes) with complicated retinal detachments without vascular eye disease or glaucoma. The flash- and flicker-evoked cortical potentials increased in amplitude in all cases. Of 21 eyes followed up for more than 50 days, eight had a 30-Hz flicker response before and after surgery. Of 13 eyes with preoperatively reduced flicker-frequency responses, ten (77%) were improved after surgery. The visual-evoked cortical potential parameters did not deteriorate in any of the patients. We concluded that no toxic effect of intravitreal liquid silicone on the optic nerve could be shown by electrophysiologic methods.
Kellner
U
U
Universitäts-Augenklinik, Essen, West Germany.
Lucke
K
K
Foerster
M H
MH
D002540:Cerebral Cortex / Q000503:physiopathology; D005074:Evoked Potentials, Visual; D006801:Humans; D007267:Injections; D009900:Optic Nerve / Q000503:physiopathology*; D010775:Photic Stimulation; D011184:Postoperative Period; D012163:Retinal Detachment / Q000503:physiopathology / Q000601:surgery*; D012828:Silicones / Q000008:administration & dosage*; D014821:Vitrectomy; D014822:Vitreous Body
D012828:Silicones