Indium-111 leukocyte accumulation in submandibular gland saliva as a cause for false-positive gut uptake in children.
Unexplained false-positive accumulation of In-111 leukocyte in the gastrointestinal tract has been reported previously. In a pediatric population, uptake in the submandibular gland was noted in 19 of 42 children. This is believed to be a normal finding in children that is not seen in adults. In some of these 19 children, unexplained gastrointestinal activity was also noted. Saliva from a patient with false-positive gastrointestinal uptake and positive submandibular activity was positive for In-111. One suggested cause of unexplained gut activity may be secondary to swallowed activity in the saliva from the normal submandibular activity in children.
Williamson
S L
SL
Department of Radiology, University of Arkansas for Medical Sciences, Little Rock.
Williamson
M R
MR
Seibert
J J
JJ
Boyd
C M
CM
Latture
T
T
D002648:Child; D004064:Digestive System / Q000000981:diagnostic imaging*; D005189:False Positive Reactions; D006801:Humans; D007205:Indium Radioisotopes; D007962:Leukocytes; D011877:Radionuclide Imaging; D012463:Saliva / Q000378:metabolism*; D013363:Submandibular Gland / Q000000981:diagnostic imaging*
D007205:Indium Radioisotopes