Sequential production of specific antibodies in serum and at the skin surface of cattle following intradermal vaccination with Dermatophilus congolensis.
Studies of the temporal changes in specific antibody titres to D. congolensis in serum and washings from inoculated and uninoculated skin indicate that production of IgG1 and IgG2 antibody at the skin surface is a transudative process related to serum antibody concentration. Transport of IgM is likely to be based on a similar mechanism but that of IgA appears to depend on a local secretory process.
Dermatology Unit, Royal Veterinary College, London, UK.
D H
DH
Lloyd
D M
DM
Jenkinson
P N
PN
Miller
T J
TJ
Sykes
D000192:Actinomycetales / Q000276:immunology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D001428:Bacterial Vaccines / Q000276:immunology*; D002417:Cattle / Q000276:immunology*; D007070:Immunoglobulin A / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D007136:Immunoglobulins / Q000096:biosynthesis; D008297:Male; D012867:Skin / Q000276:immunology*; D014611:Vaccination / Q000662:veterinary
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins