Sclerema neonatorum: a sign of transient hyperammonemia of the newborn.
We cared for four neonates with transient hyperammonemia of the newborn (THAN), all of whom exhibited sclerema during their course. Sclerema is a hardening of the subcutaneous tissues, which gives the tissue a firm, rubber-like quality. This association has not been previously reported, and it may provide a clue to early diagnosis and intervention in THAN.
Department of Pediatrics, School of Medicine, University of California, Davis 95616.
J A
JA
Lindenberg
J M
JM
Milstein
K L
KL
Cox
D000641:Ammonia / Q000097:blood*; D001806:Blood Urea Nitrogen; D002543:Cerebral Hemorrhage / Q000097:blood; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood*; D008297:Male; D009846:Oliguria / Q000097:blood; D012593:Sclerema Neonatorum / Q000097:blood*
D000641:Ammonia