Morphometric changes in sympathetic nerve fibres in diabetes.
A morphometric study was carried out on electron micrographs of lumbar sympathetic nerve fibres surgically removed from 12 patients with arteriosclerosis obliterans: 4 diabetics, 4 non-diabetics and 4 subjects with glucose intolerance. In patients with diabetes and glucose intolerance a significant decrease in the percent area fraction of unmyelinated axons and an increase in the percent area fraction of the endoneurial space were demonstrated.
Maiorana
A
A
Institute of Morbid Anatomy, University of Modena, Italy.
Cavallari
V
V
Maiorana
M C
MC
Fano
R A
RA
Scimone
S
S
Sannicola
C
C
D000368:Aged; D001369:Axons / Q000648:ultrastructure; D003920:Diabetes Mellitus / Q000473:pathology*; D005951:Glucose Tolerance Test; D006801:Humans; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000473:pathology* / Q000648:ultrastructure; D012016:Reference Values; D013564:Sympathetic Nervous System / Q000473:pathology*