Metacarpophalangeal pattern profile analysis in diastrophic dysplasia.
We analyzed the metacarpophalangeal pattern profile (MCPP) on 16 individuals with diastrophic dysplasia and calculated a mean syndrome profile. Correlation studies confirm clinical homogeneity of the hand profile in diastrophic dysplasia. Discriminant analysis of individuals with diastrophic dysplasia compared with a sample of normal individuals produced a function of 3 MCPP variables plus age that appears to be a useful diagnostic tool.
Butler
M G
MG
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Gale
D D
DD
Meaney
F J
FJ
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D003627:Data Interpretation, Statistical; D005260:Female; D005808:Genes, Recessive; D006225:Hand / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008297:Male; D008663:Metacarpus / Q000000981:diagnostic imaging*; D010009:Osteochondrodysplasias / Q000000981:diagnostic imaging* / Q000235:genetics; D011859:Radiography