[Localization of the gene coding for adenine phosphoribosyltransferase on the genetic map of chromosome 8 in the mouse].
Polymorphism of electrophoretic mobility of adenine phosphoribosyltransferase (APRT) was found in a population of domestic mice, Mus musculus bactrianus. The Aprt gene was mapped using two markers: plasma esterase 1 coded by the gene Es-1 situated at the distance of 26 morgans from the centromere, and a Robertsonian translocation Rb (8.17) 1 Iem which marks the centromere. The results of linkage analysis permitted to localize the gene Aprt at 51 morgans from the centromere, and 25 morgans distal from the gene Es-1 on the genetic map of chromosome 8. It is found that emotional stress does not alter the recombination rate at chromosome 8, when spermatocytes are at the pachytene stage.
T B
TB
Nesterova
P M
PM
Borodin
S M
SM
Zakiian
D000228:Adenine Phosphoribosyltransferase / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes / Q000648:ultrastructure*; D003433:Crosses, Genetic; D004592:Electrophoresis, Starch Gel; D005260:Female; D005796:Genes; D005815:Genetic Code; D008040:Genetic Linkage; D005838:Genotype; D008297:Male; D008677:Metaphase; D051379:Mice / Q000235:genetics*; D008815:Mice, Inbred Strains; D010430:Pentosyltransferases / Q000235:genetics*; D011110:Polymorphism, Genetic; D013315:Stress, Psychological / Q000235:genetics
D010430:Pentosyltransferases; D000228:Adenine Phosphoribosyltransferase
Lokalizatsiia gena, kodiruiushchego adenin-fosforiboziltransferazu, na geneticheskoĭ karte 8-ĭ khromosomy myshi.