Adult Henoch-Schönlein nephritis.
A retrospective study was performed of all patients at the Royal Adelaide Hospital over a ten-year period with biopsy proven Henoch-Schönlein nephritis. The records of 27 patients were examined, with emphasis on clinical and histopathological presentation, treatment and outcome. A scheme for assessing glomerular histology is presented, and severity correlated with prognosis of the disease. At presentation unfavourable prognostic indicators were acute renal impairment, crescents in greater than 20% of glomeruli, and severe glomerular histological lesions. Four patients died as a result of the disease, and 20 of the patients had evidence of continued renal abnormality at follow-up. Adult Henoch-Schönlein nephritis is a potentially catastrophic disease, and requires careful assessment at presentation.
Royal Adelaide Hospital, SA.
R J
RJ
Faull
I
I
Aarons
A J
AJ
Woodroffe
A R
AR
Clarkson
D001706:Biopsy; D005260:Female; D005500:Follow-Up Studies; D005920:Glomerular Mesangium / Q000473:pathology; D005921:Glomerulonephritis / Q000473:pathology*; D006801:Humans; D006977:Hypertension, Renal / Q000473:pathology; D011695:IgA Vasculitis / Q000473:pathology*; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000473:pathology