Hemolytic uremic syndrome associated with cisplatin therapy.
An adolescent with a small round cell tumor of the chest wall, who was treated with cisplatin, developed hemolytic uremic syndrome with severe hypertension, which ultimately contributed to her death. Cisplatin's role as a possible causative agent of this syndrome is discussed. Recommendations are made for monitoring abnormalities that may signal the onset of this potential complication.
Weinblatt
M E
ME
Department of Pediatrics, Cornell University Medical College, Manhasset, New York.
Kahn
E
E
Scimeca
P G
PG
Kochen
J A
JA
D000293:Adolescent; D002945:Cisplatin / Q000009:adverse effects*; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D012509:Sarcoma / Q000188:drug therapy; D013899:Thoracic Neoplasms / Q000188:drug therapy
D002945:Cisplatin