Determinants of serum vitamin D levels in preadolescent cystic fibrosis children.
The effects of liver disease, fat malabsorption and sunlight exposure on serum vitamin D levels were determined in 21 optimally treated preadolescent cystic fibrosis (CF) children over a 12-month period. Manifest liver disease and fat malabsorption appeared not to affect the vitamin D level. However, the level fell significantly in winter, although not below the normal range, suggesting that sunlight exposure is a more important determinant of vitamin D levels in preadolescent CF children than liver disease and fat malabsorption.
Department of Chemical Pathology, Adelaide Children's Hospital, North Adelaide, South Australia.
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Thompson
D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000097:blood* / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood / Q000172:deficiency*; D050356:Lipid Metabolism; D008107:Liver Diseases / Q000097:blood* / Q000150:complications; D008286:Malabsorption Syndromes / Q000097:blood* / Q000150:complications; D008297:Male; D013472:Sunlight; D014807:Vitamin D / Q000627:therapeutic use
D006887:Hydroxycholecalciferols; D014807:Vitamin D