Comparison of serum calcium fractions during haemodialysis and peritoneal dialysis.
Total, ultrafiltrable and ionised calcium concentrations were determined in anaerobic serum from healthy volunteers, patients immediately before and after haemodialysis and patients on continuous ambulatory peritoneal dialysis (CAPD). Protein-bound, complexed and albumin-corrected total calcium concentrations were calculated from the results. During haemodialysis, complexed calcium did not change, whereas the other fractions increased. For patients on CAPD, the total, ionised and protein-bound calcium results were frequently lower than the reference group, whereas the ultrafiltrable and albumin-corrected total calcium results were within or higher than the reference group. Albumin-corrected total calcium for all subjects correlated better with ultrafiltrable calcium than with ionised calcium. It was concluded that low ionised calcium concentrations found in CAPD patients may be related to low albumin concentrations, and the concentration of physiologically active calcium may be normal in these patients.
Department of Chemical Pathology, St. Helier Hospital, Carshalton, Surrey, UK.
P M
PM
Kelly
M R
MR
Bending
J L
JL
Barron
D000328:Adult; D000368:Aged; D002118:Calcium / Q000097:blood*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory; D011485:Protein Binding; D006435:Renal Dialysis; D012709:Serum Albumin / Q000378:metabolism
D012709:Serum Albumin; D002118:Calcium