[Regulation of the biosynthesis of aminoacylase and pigments by strains of Actinomyces of the genus Streptoverticillium].
For using actinomyceteous extracellular aminoacylase in production of optically active amino acids it is necessary to have the fermentation broth with lowered contents of extracellular pigments whose accumulation dynamics in the process of the strain growth correlates with the dynamics of the enzyme biosynthesis. The results of the studies showed that it was possible to regulate biosynthesis of the aminoacylase and pigments in the direction of increasing the enzyme production and decreasing the pigment formation by using a medium of the respective composition and providing the respective high temperature and sufficient aeration for the strains.
Oreshina
M G
MG
Penzikova
G A
GA
Bartoshevich
Iu E
IuE
D000388:Air; D000581:Amidohydrolases / Q000096:biosynthesis*; D000596:Amino Acids / Q000096:biosynthesis*; D002244:Carbon / Q000494:pharmacology; D003470:Culture Media; D009584:Nitrogen / Q000494:pharmacology; D010860:Pigments, Biological / Q000096:biosynthesis*; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism*; D013696:Temperature
D000596:Amino Acids; D003470:Culture Media; D010860:Pigments, Biological; D002244:Carbon; D000581:Amidohydrolases; C019672:aminoacylase I; D009584:Nitrogen
Reguliatsiia protesssov biosinteza aminoatsilazy i pigmentov u shtammov aktinomitsetnoĭ kul'tury iz roda Streptoverticillium.