[Simultaneous determination of total and immature neutrophil C-reactive protein in normal, diseased, and infected newborn infants].
C. reactive protein and immature neutrophils/total neutrophils ratio are measured in 146 newborns. Three groups are considered: 37 healthy, 90 pathologic non infected and 19 bacteriologically confirmed infected newborns. Pathologies other than infection do not alter CRP nor I/T. Levels lower than 20 mg/l for CRP and 0.18 for I/T are considered normal. Both tests are considered very useful for neonatal infection diagnosis (p less than 0.001). CRP shows a higher sensitivity than I/T in neonatal infection diagnosis even in its initial period (84% versus 63%).
Krauel
J
J
Hospital Infantil San Juán de Dios, Barcelona.
Salvado
A
A
Mira
A
A
Orellana
N
N
Calvet
I
I
Molina
V
V
Lizarraga
I
I
D001424:Bacterial Infections / Q000097:blood* / Q000175:diagnosis; D002097:C-Reactive Protein / Q000032:analysis*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood*; D009504:Neutrophils / Q000032:analysis*; D011237:Predictive Value of Tests
D002097:C-Reactive Protein
Determinación simultánea de la proteína C reactiva cuantitativa y de neutrófilos inmaduros en recién nacidos normales, patológicos e infectados.