[Susceptibility of the Chinese hamster (Cricetulus griseus) to parasitic infections. (1). Experimental infection with Nematospiroides (Heligmosomoides) dubius to the cortisone-treated Chinese hamster].
Chinese hamsters (Cricetulus griseus) were experimentally infected with Nematospiroides (Heligmosomoides) dubius. Though they were resistant to the infection of this parasite, they were found to become susceptible to it by the treatment with cortisone. The number of the worms in the intestine of the Chinese hamster and the number of the eggs oviposited by female worms were markedly affected by the doses of the cortisone. Egg oviposition of N. (H.) dubius ceased within 27 days post infection in the cortisone treated Chinese hamster, probably because of the expulsion of the worms. It was suggested that cortisone treatment controlled the infection of the Chinese hamster with N. (H.) dubius and the reproductive activity of this parasite.
Department of Parasitology, Asahikawa Medical College, Japan.
H
H
Kutsumi
T
T
Inaoka
K
K
Ohnishi
D000818:Animals; D003348:Cortisone / Q000494:pharmacology*; D006224:Cricetinae / Q000469:parasitology*; D003412:Cricetulus / Q000469:parasitology*; D008297:Male; D009349:Nematode Infections / Q000469:parasitology*; D009351:Nematospiroides dubius / Q000302:isolation & purification / Q000502:physiology
D003348:Cortisone