Acute myeloblastic leukemia presenting as apparent acute otitis media.
Three cases of acute myeloblastic leukemia of FAB-M2 type revealed by an isolated otitis media are reported. This mean of revelation is valuable for early diagnosis and treatment of the disease. A karyotype was performed in two cases and showed an 8;21 translocation. As far as we know, these are the first acute myeloblastic leukemia cases with otitis media reported in which an 8;21 translocation was detected.
Service de Pédiatrie, Hôpital Trousseau, Paris, France.
Y
Y
Bertrand
J J
JJ
Lefrère
G
G
Leverger
M
M
Bonnet
H
H
Lacombe
G
G
Lasfargues
D000208:Acute Disease; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000235:genetics; D008297:Male; D010033:Otitis Media / Q000175:diagnosis*