Guidelines for maintenance treatment of childhood asthma: development of a score card system by multivariate cluster analysis.
Multivariate cluster analysis of data on 128 asthmatic children resulted in the identification of 8 major discriminating variables. Stepwise divisions by this computer programme resulted in the formation of 6 grades of severity. There was significant correlation between higher grades of severity and early onset of the disease (P less than 0.02). There was also significant correlation between higher grades of severity and greater use of interval medications (P less than 0.002). However, 27.3% were receiving inadequate interval medications in respect of their grade of severity. Assignation of a 5-point scale to each of the 8 major discriminating variables resulted in the generation of computer-designated scores commensurate with each grade of severity. This was coupled to current recommendations for stepwise maintenance medications appropriate for each grade. This Score Card system for maintenance management of childhood asthma may prove useful in busy clinical settings.
Donnelly
W J
WJ
Department of Child Health, University of Queensland, Mater Children's Hospital, South Brisbane, Australia.
Donnelly
J E
JE
Thong
Y H
YH
D000293:Adolescent; D000367:Age Factors; D001249:Asthma / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004360:Drug Therapy, Computer-Assisted; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013813:Therapy, Computer-Assisted