Aspiration biopsy cytology of adenocarcinoid tumor of the bronchial tree.
Aspirated material from two cases of histologically and ultrastructurally confirmed adenocarcinoid tumor of the lung was evaluated. In one case, columnar and cuboidal cells with ill-defined cytoplasm and round or oval nuclei were seen in large sheets and syncytiumlike clusters with focal glandular arrangement. In the other case, spindle-shaped and columnar cells with ovoid nuclei and ill-defined cytoplasm were seen singly and in loose clusters. Fragments of tumor epithelium with nuclei arranged in pseudo-stratified pattern were noted. Staining of tumor cells by the Grimelius technique demonstrated numerous intracytoplasmic brown-black granules. The cytologic differential diagnosis between adenocarcinoid tumor and other primary and metastatic adenocarcinomas of the lung is briefly discussed.
Department of Pathology, University of Alberta Faculty of Medicine, Edmonton, Canada.
G K
GK
Nguyen
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Shnitka
D001707:Biopsy, Needle; D001984:Bronchial Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D002276:Carcinoid Tumor / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron