Degradation of naphthalene-2,6- and naphthalene-1,6-disulfonic acid by a Moraxella sp.
A naphthalene-2,6-disulfonic acid (2,6NDS)-degrading Moraxella strain was isolated from an industrial sewage plant. This culture could also be adapted to naphthalene-1,6-disulfonic acid as growth substrate. Regioselective 1,2-dioxygenation effected desulfonation and catabolism to 5-sulfosalicylic acid (5SS), which also could be used as the sole carbon source. 5SS-grown cells exhibited high gentisate 1,2-dioxygenase activity. Neither 5SS- nor gentisate-grown cells oxidized 2,6NDS; therefore, 2,6NDS or an early metabolite must serve as an inducer of the initial catabolic enzyme(s).
Bernhard-Nocht-Institut für Schiffs- und Tropenkrankheiten, Abteilung für Biochemie, Hamburg, Federal Republic of Germany.
R M
RM
Wittich
H G
HG
Rast
H J
HJ
Knackmuss
D001557:Benzenesulfonates; D001673:Biodegradation, Environmental; D002384:Catalysis; D003470:Culture Media; D005841:Gentisates / Q000378:metabolism; D009016:Moraxella / Q000302:isolation & purification / Q000378:metabolism*; D009282:Naphthalenesulfonates / Q000378:metabolism*; D010084:Oxidation-Reduction; D012459:Salicylates / Q000378:metabolism; D013455:Sulfur / Q000378:metabolism
D001557:Benzenesulfonates; D003470:Culture Media; D005841:Gentisates; D009282:Naphthalenesulfonates; D012459:Salicylates; C056937:naphthalene-1,6-disulfonic acid; C056940:naphthalene-2,6-disulfonic acid; D013455:Sulfur; C003366:sulfosalicylic acid