Japanese Graves' disease: association with HLA-Bw46.
HLA-A, -B, and -C antigen frequency of 61 Japanese patients with Graves' disease, and HLA-DR and -DQ frequency of 53 patients with it were compared that of 1,998 controls. The prevalence of Bw46 was significantly higher in patients with Graves' disease (23.0% vs 8.4%, Pc less than 0.003). The result was quite different from previous reports on Japanese Graves' disease.
Department of Internal Medicine, Fukuoka University Medical School, Japan.
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S
Naito
H
H
Sasaki
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K
Arakawa
D000293:Adolescent; D000328:Adult; D005260:Female; D006111:Graves Disease / Q000276:immunology*; D006680:HLA Antigens / Q000032:analysis*; D006681:HLA-D Antigens / Q000032:analysis; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged
D006680:HLA Antigens; D006681:HLA-D Antigens