Autopsy findings in a Japanese patient with acquired immunodeficiency syndrome.
A 37-year-old Japanese man was diagnosed as having acquired immunodeficiency syndrome (AIDS) on the basis of a homosexual history, generalized lymphadenopathy, marked decrease of helper/inducer T cells in the peripheral blood, and positive serum antibody (antibodies) against human immunodeficiency virus (human T-lymphotropic virus type III/lymphadenopathy-associated virus). Autopsy showed severe depletion of lymphocytes in the lymphoid organs including the systemic lymph nodes, spleen, and gut-associated lymphoid tissue. Pneumocystis carinii pneumonia and adrenal cytomegalovirus infection ('necrotizing adrenalitis') were identified, but there was no neoplasm. Postmortem findings in AIDS were reviewed in the literature.
Department of Laboratory Medicine, Wakayama Medical School, Japan.
H
H
Nakamine
E
E
Shimizu
E
E
Nishino
T
T
Takenaka
J
J
Maeda
M
M
Hanaoka
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D000311:Adrenal Glands / Q000473:pathology; D000328:Adult; D001344:Autopsy; D006716:Homosexuality; D006801:Humans; D007564:Japan; D008168:Lung / Q000473:pathology; D008221:Lymphoid Tissue / Q000473:pathology; D008297:Male; D013154:Spleen / Q000382:microbiology