[Association of cerebral cysticercosis and multifocal glioma. Discussion of interactions].
Diagnosis in a case of cerebral parenchyma cysticercosis was based on conventional arguments described in the literature. The patient died after progression of the disease over 6 months, despite two courses of Praziquantel. Results of neuropathologic examination confirmed diagnosis of cysticercosis and the discovery of a multifocal astrocytic tumor involving mainly the periventricular regions. Possible interactions between parasitic infection and glioma are discussed but it is difficult to determine the precise role played by the parasitosis in the evolution of the tumor, the hypothesis of a simple coincidence being most likely. Periventricular images of an inflammatory nature observed after PZQ treatment should not be accepted unreservedly, and when an unfavorable course is apparent the periventricular histopathologic lesions should be compared with results of CT scan imaging qualified as periventricular in origin.
Centre Hospitalier St-Philibert, Lomme, Service de Neurologie.
P
P
Hautecoeur
P
P
Gallois
J M
JM
Brucher
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E
Ovelacq
J F
JF
Dereux
D001927:Brain Diseases / Q000150:complications* / Q000188:drug therapy; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D003551:Cysticercosis / Q000150:complications* / Q000188:drug therapy; D005260:Female; D005910:Glioma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use
D011223:Praziquantel
Association d'une cysticercose cérébrale et d'un gliome multifocal. Discussion des interactions.