[Isolated muscular tuberculosis in dermatomyositis treated with corticosteroids. Developing outbreak of dermatomyositis under rifampicin treatment. 2 cases].
The authors report two cases of muscular tuberculosis in patients with dermatomyositis treated with steroids. Antituberculous therapy with Rifampicin led to a severe relapse of the dermatomyositis in both cases, suggesting enzymatic induction inhibiting the action of the steroids.
Service de Rhumatologie, C. H. U. Pitié-Salpêtrière, Paris.
J P
JP
Camus
A C
AC
Koeger
K
K
Nahoul
D
D
Alcaix
L
L
Gutmann
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D003882:Dermatomyositis / Q000139:chemically induced / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000150:complications* / Q000188:drug therapy; D012008:Recurrence; D012293:Rifampin / Q000009:adverse effects / Q000627:therapeutic use; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D012293:Rifampin
Tuberculose musculaire isolée au cours d'une dermatomyosite traitée par corticothérapie. Poussée évolutive de la dermatomyosite sous rifampicine. Deux observations.