Congenital anal anomalies in two families with the Opitz G syndrome.
Five children from two families presented to a regional neonatal surgical unit between 1959 and 1984 with congenital anal anomalies and other malformations resulting from an autosomal dominant inherited condition, the Opitz G syndrome. This and other Mendelian causes of congenital anal malformations are briefly discussed in view of their importance for genetic counselling.
Tolmie
J L
JL
Duncan Guthrie Institute of Medical Genetics, Yorkhill, Glasgow.
Coutts
N
N
Drainer
I K
IK
D000015:Abnormalities, Multiple / Q000235:genetics*; D001006:Anus, Imperforate / Q000235:genetics* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D005799:Genes, Dominant; D006801:Humans; D006972:Hypertelorism / Q000235:genetics; D007223:Infant; D008297:Male; D010375:Pedigree; D013577:Syndrome