[Role of myocardial scintigraphy with thallium-201 in the characterization of episodes of transient ischemia at rest. Clinical and electrocardiographic correlates].
In the past ten years we studied 80 patients with angina at rest by 201-Thallium perfusion scintigraphy. According to ECG changes during episodes of transient ischemia at rest, the patients were divided into three groups. Thirty six patients showed transient ST segment elevation (Group 1); 33 ST segment depression (Group 2) and 11 normalization of negative T waves (Group 3). 201-TI scintigraphy was performed during spontaneous or ergonovine induced episodes of ischemia and at redistribution. Group 1 showed localized and severe perfusion defects, well correlated to the site of ECG changes. Group 2 showed more diffuse and less severe perfusion defects, less correlated to the site of ECG changes. Group 3 showed perfusion defects similar to those observed in Group 1 and associated in 54% with basal perfusion defects due to previous myocardial infarction.


CONCLUSIONS
A) three main perfusion patterns are associated with the three types of ECG changes; B) relative to ECG, myocardial scintigraphy provides a more accurate definition of the site and extension of ischemia, particularly in Group 2 patients.
Istituto di Fisiologia Clinica del CNR, Università degli Studi di Pisa.
C
C
Marcassa
O
O
Parodi
P
P
Marzullo
D
D
Neglia
A
A
Fontana
S
S
Severi
A
A
L'Abbate
D000328:Adult; D000368:Aged; D003326:Coronary Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003329:Coronary Vasospasm / Q000000981:diagnostic imaging / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012146:Rest; D013794:Thallium Radioisotopes
D013794:Thallium Radioisotopes
Ruolo della scintigrafia miocardica con tallio-201 nella caratterizzazione di episodi di ischemia transitoria a riposo. Correlazioni cliniche ed elettrocardiografiche.