Reduced concentrations of ascorbic acid and glutathione in a single case of Rett syndrome: a postmortem brain study.
Preliminary data of a postmortem brain study in a single case with Rett syndrome compared to a single control case showed a severe reduction of ascorbic acid and reduced glutathione in most brain regions studied. These findings suggest a secondary disturbance of ascorbic acid and glutathione metabolism in the Rett syndrome.
Department of Psychiatry, University of Würzburg, FRG.
E
E
Sofić
P
P
Riederer
W
W
Killian
A
A
Rett
D001205:Ascorbic Acid / Q000032:analysis*; D001923:Brain Chemistry; D001927:Brain Diseases / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism; D002648:Child; D005260:Female; D005978:Glutathione / Q000032:analysis*; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism; D013577:Syndrome
D005978:Glutathione; D001205:Ascorbic Acid