[Which studies are suitable for the diagnosis of recurrences in resectable breast carcinoma? A retrospective analysis of the OSAKO 06/74 adjuvant study].
113 patients with first relapse in the OSAKO 06/74 adjuvant chemotherapy trial for resectable breast cancer were investigated retrospectively. Based on history alone, 85% of the relapses could have been presumed. Physical examination alone was positive in 82% of relapses. Depending on the localization of relapse, the relative importance of different methods of examination differed. If history and physical examination were analyzed together, 96% of all relapses could be presumed. 45% of the patients did not see the doctor before the fixed time, although they suffered from symptoms associated with relapse. 26% of the women complained of symptoms during at least 4 months before diagnosis of relapse. We conclude that regular clinical controls, including careful history and scrupulous physical examination, represent the most efficient method for diagnosis of relapse in patients with resectable breast cancer.
Abteilung für Onkologie und Hämatologie, Kantonsspital, St. Gallen.
A
A
Streit
L
L
Schmid
W F
WF
Jungi
H J
HJ
Senn
D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008487:Medical History Taking; D009362:Neoplasm Metastasis; D010808:Physical Examination; D012189:Retrospective Studies
Welche Untersuchungen sind zur Diagnose von Rezidiven beim operablen Mammakarzinom geeignet? Eine retrospektive Analyse der Adjuvans-Studie OSAKO 06/74.