[Combination of drugs and clean intermittent catheterization in the treatment of neurogenic bladder. Effect on continence].
We report the results obtained with the association of drugs with clean intermittent catheterization (CIC) in 13 patients with neurogenic bladder due to spina bifida. The drugs used were bladder muscle relaxants (imipramine), anticholinergic (probanthine) and/or alpha-adrenergic (ephedrine). CIC alone led to acceptable continence in only 24% of cases, whereas with the addition of drugs this proportion increased to 80%. All along the treatment upper urinary tract remained stable in all patients, there were no changes in asymptomatic bacteriuria when present and collateral effects were minimal.
Jiménez
J
J
Departamento de Pediatría, Hospital Materno-Infantil Nuestra Señora de Aránzazu, San Sebastián.
Arruebarrena
D
D
Rodríguez
J
J
Urbieta
M A
MA
Arriola
M
M
Aresès
R
R
D002648:Child; D002675:Child, Preschool; D004809:Ephedrine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D011413:Propantheline / Q000627:therapeutic use; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy*; D014546:Urinary Catheterization; D014549:Urinary Incontinence / Q000188:drug therapy*
D011413:Propantheline; D004809:Ephedrine; D007099:Imipramine
Asociación de fármacos al cateterismo intermitente limpio en el tratamiento de la vejiga neurógena. Efecto sobre la continencia.