Evaluation of radiocardiographic methods for determination of cardiac output and right and left ventricular ejection fractions using a cardiac phantom.
Cardiac output and ejection fractions of the cardiac ventricles are valuable measures of cardiac function. Noninvasive radionuclide techniques for determination of these measures are based on analysis of different data: first passage low frequency, first passage high frequency and multigated equilibrium data. We have evaluated the principles of these methods using a dynamic cardiac phantom. Radiocardiographic determinations of cardiac output and right and left ventricular ejection fractions showed excellent correlation against true phantom values: r = 0.993 (p less than 0.001), r = 0.978 (p less than 0.01) and r = 0.943 (p less than 0.05), respectively. Thus, the findings of the present study demonstrate a high validity of current radiocardiographic measures of cardiac function.
Department of Clinical Physiology and Nuclear Medicine, Herlev Hospital, University of Copenhagen, Denmark.
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H
Kelbaek
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H
Jensen
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PV
Madsen
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O
Munck
D002302:Cardiac Output; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008955:Models, Cardiovascular; D008961:Models, Structural; D011877:Radionuclide Imaging; D013318:Stroke Volume