Natural history and treatment of anorectal strictures complicating Crohn's disease.
Forty-four patients seen between 1975 and 1985 with anorectal strictures complicating Crohn's disease have been reviewed to determine the natural history and outcome of surgical treatment. Proctitis was present in 98 per cent, and 93 per cent of patients had sever perianal disease. The site of strictures was rectal in 22, anal in 15 and anorectal in 11 (4 patients had a stricture at 2 sites). Initial treatment was by rectal excision alone in 6, dilatation in 33, and 5 needed no treatment at all. Single dilatation was effective in 15, 8 required two dilatations and in 10 repeated dilatation was necessary. Proctocolectomy was eventually required in 19 patients, 2 have a loop ileostomy and 1 has an ileostomy with a rectal stump in situ. Only 21 remain asymptomatic while 3 continue to need dilatation. Perineal wound healing was delayed in 9 of 19 patients having a proctocolectomy and in 3 the perineal wound has never healed.
Department of Surgery, General Hospital, Birmingham, UK.
L
L
Linares
L F
LF
Moreira
H
H
Andrews
R N
RN
Allan
J
J
Alexander-Williams
M R
MR
Keighley
D000293:Adolescent; D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000473:pathology; D001004:Anus Diseases / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D002404:Catheterization; D003251:Constriction, Pathologic; D003424:Crohn Disease / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012002:Rectal Diseases / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D012007:Rectum / Q000473:pathology; D014945:Wound Healing