[Characteristics of the premanifest period of late schizophrenia with the picture of an involutional paranoid].
Study of the premanifest period in 65 patients with schizophrenia that first manifested in old age by the "involutional paranoid" syndrome demonstrated that most patients presented signs of a torpid (17.5%) or a latent (68%) course of the schizophrenic process already in young or middle age. In only 14.5% of cases the pre-manifest period was characterized by personality accentuation. Analysis of cases of the latent course of the disease has made it possible to distinguish three main variants of its clinical manifestations: hypoparanoid, psychopathy-like and neurosis-like. On the basis of these findings a conclusion can be drawn that most of the cases of schizophrenia manifested in old age by the syndrome of involutional paranoid belong to a group of diseases with an early onset, prolonged torpid or latent course, and with increased progression of the process in advanced age.
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Zharkova
D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D011599:Psychopathology; D012563:Schizophrenia, Paranoid / Q000175:diagnosis* / Q000523:psychology; D012569:Schizotypal Personality Disorder / Q000175:diagnosis / Q000523:psychology
Osobennosti domanifestnogo perioda pozdneĭ shizofrenii s kartinoĭ involiutsionnogo paranoida.