Errors in spin-lattice relaxation time measurements from restricted volumes.
In vivo T1 measurements are usually made from images. In this paper we describe an alternative method in which data are collected from a strip instead of from an entire plane. We will compare the signal-to-noise ratios, the time to make a measurement, and the error in T1 as well as other aspects of the two methods. We have found that the strip method has less inherent signal-to-noise, but that this may be compensated for by taking measurements at more than the usual two repetition rates. The method employs a selective 180 degree pulse as well as a selective 90 degree pulse. It is shown that both pulses effectively isolate the region of interest.
Morrone
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Fonar Corporation, Melville, New York 11747.
D003198:Computer Simulation; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008433:Mathematics