Secreto-motor function of intestinal segments used in lower urinary tract reconstruction.
Mucus excretion, sialic acid excretion and secretory IgA (sIgA) production from patients with a substitution caecocystoplasty (20), augmentation "clam" ileocystoplasty (20) or ileal conduit (10) were measured. Significant amounts of all of these substances were present in the urine of reconstructed patients and showed no evidence of diminution with time. Motility was studied by videocystourethrography. In patients with a neuropathic aetiology the amplitude of contractions was significantly increased and produced incontinence. The results demonstrate that intestinal secreto-motor function in gut segments incorporated into the lower urinary tract continues normally and must be taken into account when considering the long-term management of these patients.
Department of Surgery, Guy's Hospital, London.
K
K
Murray
D E
DE
Nurse
A R
AR
Mundy
D003106:Colon / Q000378:metabolism / Q000502:physiology* / Q000637:transplantation; D005260:Female; D006801:Humans; D007082:Ileum / Q000378:metabolism / Q000502:physiology* / Q000637:transplantation; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D008297:Male; D009043:Motor Activity; D009119:Muscle Contraction; D001743:Urinary Bladder / Q000601:surgery; D014547:Urinary Diversion; D014551:Urinary Tract / Q000601:surgery*
D007071:Immunoglobulin A, Secretory