[Characteristics of prolactin secretion in patients with different types of gonadal dysgenesis].
A study was made of the level of prolactin in the blood plasma of 55 patients aged 16 to 23 with different types of gonad dysgenesia. It was shown for the first time that in most of the patients with gonad dysgenesia disregarding pathology type the level of prolactin did not differ from that in the follicular phase of the menstrual cycle of healthy girls, and was significantly decreased as compared to the level of this hormone in the luteal phase. Estrogen therapy caused a considerable rise of the prolactin level in all the examines. The detection of hyperprolactinemia in patients with gonad dysgenesia can indicate a possibility of the development of microadenomas of the hyperstimulated hypophysis in them.
Benikova
E A
EA
Bol'shova
E V
EV
D000293:Adolescent; D000328:Adult; D004958:Estradiol / Q000097:blood; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006059:Gonadal Dysgenesis / Q000503:physiopathology*; D006061:Gonadal Dysgenesis, 46,XY / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D011388:Prolactin / Q000378:metabolism*; D014424:Turner Syndrome / Q000188:drug therapy / Q000503:physiopathology*
D004967:Estrogens; D004958:Estradiol; D011388:Prolactin
Osobennosti sekretsii prolaktina u bol'nykh s razlichnymi vidami disgenezii gonad.