Dependency of resistance of mice immunized against Taenia crassiceps on the dose of soluble antigen.
Mice immunized with a single dose (1.25-40 micrograms/mouse) of soluble antigen from Taenia crassiceps cysticerci developed a 62.9-85.0% resistance. Maximum effect was achieved in the groups immunized with 40 micrograms and 20 micrograms of antigen. The dose of 5 micrograms induced the lowest number of successful infections (28.6%), but the mean number of surviving larvae was higher than in the above groups.
Lukes
S
S
Institute of Parasitology, Czechoslovak Academy of Sciences, Ceské Budĕjovice.
D000818:Animals; D000947:Antigens, Helminth / Q000008:administration & dosage / Q000276:immunology*; D003551:Cysticercosis / Q000276:immunology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D007114:Immunization; D007814:Larva / Q000254:growth & development / Q000276:immunology; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D013621:Taenia / Q000254:growth & development / Q000276:immunology*
D000947:Antigens, Helminth