Genetic heterogeneity of S-formylglutathione hydrolase.
S-formylglutathione hydrolase from erythrocytes has been studied by an electrophoretic technique. Three phenotypes were observed in a number of racial groups. The electrophoretic polymorphism was shown to be the product of two alleles at a single locus termed FGH. The product of the type 2 allele was found to be relatively unstable.
John Curtin School of Medical Research, Australian National University, Canberra, A.C.T.
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D000483:Alleles; D043182:Carboxylesterase; D004355:Drug Stability; D004592:Electrophoresis, Starch Gel; D004912:Erythrocytes / Q000201:enzymology; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D010641:Phenotype; D013869:Thiolester Hydrolases / Q000235:genetics*
D043182:Carboxylesterase; C020118:ESD protein, human; D013869:Thiolester Hydrolases; C020149:s-formylglutathione hydrolase