Long term amantadine treatment. The danger of withdrawal.
Three elderly Parkinsonian patients on long term amantadine therapy (mean nine years) are presented. In each case abrupt withdrawal of amantadine resulted in rapid deterioration in the patient's condition which was corrected by reintroduction of amantadine.
Wilson
J A
JA
Department of Geriatric Medicine, City Hospital, Edinburgh.
Farquhar
D L
DL
Primrose
W R
WR
Smith
R G
RG
D000368:Aged; D000547:Amantadine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy*; D012008:Recurrence
D000547:Amantadine