Semiological analysis of Raynaud attacks.
Careful semiological and etiological investigations (including nailfold capillary microscopy) were performed in 120 consecutive patients with Raynaud phenomenon (RP) (December 1983-March 1984) recorded on a standardized form. Complete and reliable data were obtained in 103 cases. The functional severity of the attacks was assessed statistically, after adjusting for etiological groups. The existence of an asphyxial (cyanotic) phase was found the best single criterion for the severity of attacks, but a more complete evaluation was arrived at with the following functional severity score (FSS = 0 to 3): asphyxia (0 or 1)+summer rate of attacks higher than once a week (0 or 1)+involvement of all the fingers (0 to 1). This score was also validated through a multivariate correspondence analysis. FSS was much higher in RP associated with connective tissue diseases (1.73 +/- 0.18) than in primary RP (0.64 +/- 0.14, p less than 0.001). A careful analysis of ischemic attacks is thought to be an important part of etiological and pre-therapeutic evaluation of patients with RP.
Laboratoire d'Hemodynamique Peripherique et de Microcirculation, C.H.U. de Grenoble, France.
P
P
Carpentier
P
P
Laperrousaz
J L
JL
Magne
F
F
Dubois
R
R
De Gaudemaris
J M
JM
Diamand
A
A
Franco
D003080:Cold Temperature / Q000009:adverse effects; D003240:Connective Tissue Diseases / Q000503:physiopathology; D005121:Extremities / Q000098:blood supply; D006801:Humans; D006940:Hyperemia / Q000503:physiopathology; D007511:Ischemia / Q000503:physiopathology; D011928:Raynaud Disease / Q000503:physiopathology*; D012867:Skin / Q000098:blood supply; D014666:Vasomotor System / Q000503:physiopathology