Synovial metastasis of an adenocarcinoma presenting as a shoulder monoarthritis.
A 96-year-old woman presented with monoarthritis of the shoulder from a metastasis affecting both the synovium and the humeral head. Evidence of the metastatic process was based on cytologic study of the synovial fluid (SF), synovial membrane and adjacent bone. A primary cancer site was not discovered. The carcinoembryonic antigen level of SF was greatly enhanced. A similar elevation was not detected in other arthropathies (20 control cases).
Benhamou
C L
CL
Department of Rheumatology, Orleans La Source, France.
Tourliere
D
D
Brigant
S
S
Maitre
F
F
Cauderlier
P
P
D000230:Adenocarcinoma / Q000473:pathology* / Q000556:secondary; D000368:Aged; D000369:Aged, 80 and over; D001168:Arthritis / Q000175:diagnosis*; D001706:Biopsy; D001859:Bone Neoplasms / Q000473:pathology* / Q000556:secondary; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D005353:Fibronectins / Q000032:analysis; D006801:Humans; D006811:Humerus / Q000473:pathology*; D012785:Shoulder Joint; D013582:Synovial Fluid / Q000032:analysis; D013583:Synovial Membrane / Q000473:pathology*
D002272:Carcinoembryonic Antigen; D005353:Fibronectins