Factors affecting the normal perimetric profile derived by automated static threshold LED perimetry. II. Accommodative microfluctuations.
The relationship between accommodative fluctuations and perimetric sensitivity was investigated in a group of 10 clinically normal emmetropic subjects using the Dicon AP3000 computer-assisted perimeter at a bowl luminance of 10 asb. Accommodative microfluctuations were attenuated with the antimuscarinic drug cyclopentolate HCl 1% and the concomitant mydriasis was matched on a separate trial using the sympathomimetic phenylephrine HCl 10%. Saline 0.9% was used as the control. Accommodative microfluctuations were found to play a minor role in determining the magnitude of sensitivity out to an eccentricity of 5 degrees; between 5 degrees and 27.5 degrees, the effect of microfluctuations was masked by the mydriasis produced by the drugs used in the study. The range of sensitivity values at a given location were reduced when accommodative fluctuations were minimized.
Wood
J M
JM
Department of Vision Sciences, Aston University, Birmingham, UK.
Bullimore
M A
MA
Wild
J M
JM
Gilmartin
B
B
D000065:Accommodation, Ocular / Q000187:drug effects; D000328:Adult; D003519:Cyclopentolate / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D010656:Phenylephrine / Q000494:pharmacology; D058609:Visual Field Tests; D014794:Visual Fields
D010656:Phenylephrine; D003519:Cyclopentolate