Serum bile-acids in liver cirrhosis: prognostic significance evidenced by a multivariate statistical model.
In order to evaluate the prognostic value of serum bile acids (SBA) in liver cirrhosis, we compared SBA levels with a theoretical expected survival length (ESL), computed on the ground of a previously proposed and validated multivariate statistical model. We demonstrated a strict correlation between SBA levels and ESL in subjects with liver cirrhosis by means of both standard linear correlation analysis and Logrank test. Our results account for a high predictive significance of SBA levels in liver cirrhosis, even in long term prognosis.
Istituto di Patologia Medica, Universita' Cattolica S. Cuore, Roma.
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M
Siciliano
A
A
Milani
L
L
Marra
L
L
Rossi
D000328:Adult; D000368:Aged; D001647:Bile Acids and Salts / Q000097:blood*; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood* / Q000401:mortality; D008104:Liver Cirrhosis, Alcoholic / Q000097:blood; D008297:Male; D008875:Middle Aged; D011379:Prognosis
D001647:Bile Acids and Salts