A comparative study between midazolam and thiopental alone or with analgesic and neuroleptic as intravenous induction agents in general anesthesia.
We compared midazolam with thiopental both in association with saline, fentanyl and fentanyl with droperidol for induction of anesthesia. Our data show that the administration of fentanyl or fentanyl and droperidol before midazolam improves the induction to reach almost the quality of a thiopental induction. No difference in cardiocirculatory effects between midazolam and thiopental was found.
Vandermeersch
E
E
Department of Anesthesiology, Katholieke Universiteit, Leuven, Belgium.
Van Aken
H
H
D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D000771:Anesthesia, Intravenous; D001794:Blood Pressure / Q000187:drug effects; D004329:Droperidol / Q000008:administration & dosage; D004338:Drug Combinations; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008874:Midazolam / Q000008:administration & dosage*; D008875:Middle Aged; D013874:Thiopental / Q000008:administration & dosage*
D004338:Drug Combinations; D013874:Thiopental; D004329:Droperidol; D008874:Midazolam; D005283:Fentanyl