Fast imaging of CSF flow/motion patterns using steady-state free precession (SSFP).
Using a rapid Fourier SSFP imaging technique, which is sensitive to slow flow (approximately 1 mm/sec) in the plane of the image, we obtained 135 brain MRI examinations. The CSF flow/motion patterns were mapped by two images with orthogonal in plane flow sensitivity directions. Analysis showed significant deviations from the "normal" pattern in ventricular enlargements because of obstruction (no evidence of CSF flow/motion) or in normal pressure hydrocephalus (complex, intensive flow pattern in lateral ventricles) suggesting a diagnostic potential for this fast imaging technique.
Department of Radiology, Harvard Medical School, Boston, Massachusetts.
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Jolesz
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Patz
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Hawkes
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Lopez
D001921:Brain / Q000473:pathology*; D002555:Cerebrospinal Fluid / Q000502:physiology; D005583:Fourier Analysis; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis*; D006850:Hydrocephalus, Normal Pressure / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012212:Rheology