An MRI phantom material for quantitative relaxometry.
Most phantom media in current use exhibit T1 relaxation times that are significantly dependent on both temperature and operating frequency. This can introduce undesirable variability into relaxation measurements due to temperature fluctuations, and complicates direct comparison of imagers operating at different magnetic field strengths. Our investigations of a nickel-doped agarose gel system have demonstrated near independence of the proton relaxation rates to a wide range of temperatures and frequencies. We therefore propose the adoption of Ni2+ as a relaxation modifier for phantom materials used as relaxometry standards.
Department of Radiology, Medical College of Virginia/Virginia Commonwealth University, Richmond 23298.
K A
KA
Kraft
P P
PP
Fatouros
G D
GD
Clarke
P R
PR
Kishore
D003300:Copper; D008279:Magnetic Resonance Imaging; D008345:Manganese; D009532:Nickel; D012685:Sepharose; D013696:Temperature
D008345:Manganese; D003300:Copper; D009532:Nickel; D012685:Sepharose