[Effectiveness of finlepsin in the prophylactic therapy of phasic affective psychoses].
The article presents new, specified results of the use of finlepsin (carbamazepine) for the secondary prophylaxis in patients with endogenic affective psychoses. The data have emanated from a 5-year observation of the course of therapy of 73 patients. A positive effect was observed in 83% of cases, including 27.7% of cases with complete disappearance of circulation. No significant differences in the drug efficacy have been found in patients with manic-depressive psychosis versus schizophrenia. Yet, in most of the schizophrenics the phases have disappeared, while patients with manic-depressive psychosis have presented only partial improvement. The authors recommend that doses at the initial stages of treatment be increased in a gradual manner. Variants of a positive therapeutic time-course are described. They have also determined a period of time (3.5-4 months) after which the continuation of the therapy should be considered inadvisable in case of no favourable effect.
R Ia
RIa
Vovin
A I
AI
Skorik
I O
IO
Aksenova
A G
AG
Digilov
A A
AA
Firulev
D000328:Adult; D000341:Affective Disorders, Psychotic / Q000517:prevention & control*; D001714:Bipolar Disorder / Q000517:prevention & control; D002220:Carbamazepine / Q000627:therapeutic use*; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010507:Periodicity; D012074:Remission Induction; D012559:Schizophrenia / Q000517:prevention & control; D013997:Time Factors
D002220:Carbamazepine
Effektivnost' finlepsina pri profilakticheskoĭ terapii fazno protekaiushchikh affektivnykh psikhozov.