Simplifying infusion chemotherapy: preliminary communication.
A low-intervention policy for Hickman catheter maintenance has been evaluated and found to be safe and cost effective. A simple, lightweight, disposable device has been used for 24-hour ambulatory home infusion. Implementation of this policy as part of a prospective randomized trial of single-agent chemotherapy in advanced breast cancer has demonstrated that slow intravenous infusion reduces the acute toxicity of epirubicin when compared with bolus injection.
Department of Surgery, King's College Hospital, Rayne Institute, London.
S R
SR
Ebbs
J A
JA
Saunders
J V
JV
Roberts
M
M
Baum
T
T
Bates
J E
JE
Morris
D001943:Breast Neoplasms / Q000188:drug therapy*; D002406:Catheterization, Peripheral; D004317:Doxorubicin / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D015251:Epirubicin; D006801:Humans; D007262:Infusions, Intravenous / Q000379:methods; D013237:Stereoisomerism
D015251:Epirubicin; D004317:Doxorubicin