[Efficacy of diclofenac continuous perfusion in hyperalgic bone metastases. Apropos of 20 cases treated at Gustave Roussy Institute].
In this trial, 20 patients suffering from bone metastasis pain received diclofenac, a non-steroid anti-inflammatory agent, by continuous IV infusion. No pain was observed in 77% after 2.7 days of treatment. 33% of bedridden patients were able to move again. Two patients (10%) presented gastric pain controlled by symptomatic treatment.
Institut Gustave-Roussy, Unité La Grange, Savigny-le-Temple, France.
M
M
Benahmed
P
P
Wibault
B
B
Court
P
P
Kple Faget
H
H
Ammarguellat
E
E
Pichard
D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000188:drug therapy / Q000556:secondary*; D004008:Diclofenac / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*
D004008:Diclofenac
Efficacité du diclofenac en perfusion continue dans les métastases osseuses hyperalgiques. A propos de 20 cas traités à l'Institut Gustave-Roussy.