[Heart muscle proteins of an inbred mouse strain carrying the autosomal-recessive form of generalized myodystrophy].
The study of the polypeptide structure of cardiac muscle proteins of the inbred mice 129 Re + dy/dy by two-dimensional electrophoresis has revealed quantitative and qualitative variations in four polypeptides out of 161 analyzed ones. It is supposed that the protein fractions N 14 and O 13 may contribute to the development of cardiac pathology. Gene-dosage dependence is identified for the fraction O 13.
Kovalev
L I
LI
Puliaeva
E V
EV
Shishkin
S S
SS
D000818:Animals; D002869:Chromosome Aberrations / Q000235:genetics / Q000378:metabolism*; D025063:Chromosome Disorders; D005808:Genes, Recessive; D006579:Heterozygote; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains / Q000235:genetics / Q000378:metabolism*; D009124:Muscle Proteins / Q000032:analysis*; D009137:Muscular Dystrophy, Animal / Q000235:genetics / Q000378:metabolism*; D009206:Myocardium / Q000032:analysis*; D010641:Phenotype
D009124:Muscle Proteins
Izuchenie belkov serdechnoĭ myshtsy inbrednoĭ linii mysheĭ, nesushcheĭ autosomno-retsessivnuiu formu generalizovannoĭ miodistrofii.