The ontogeny of various cell populations defined by monoclonal antibodies in the primary lymphoid organs of the sheep.
Monoclonal antibodies specific for various cell surface markers in sheep were employed to study the ontogeny of the immune system in this species. The temporal sequence of appearance of various cell populations of hematopoietic origin is described in the course of fetal development of the liver, spleen, thymus, ileal Payer's patches and bone marrow.
Basel Institute for Immunology, Switzerland.
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Miyasaka
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology*; D001853:Bone Marrow / Q000196:embryology; D001854:Bone Marrow Cells; D005333:Fetus / Q000276:immunology; D008214:Lymphocytes / Q000145:classification*; D008221:Lymphoid Tissue / Q000166:cytology* / Q000196:embryology / Q000276:immunology; D010581:Peyer's Patches / Q000166:cytology / Q000196:embryology; D012756:Sheep / Q000196:embryology / Q000276:immunology*; D013950:Thymus Gland / Q000166:cytology / Q000196:embryology
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface