[Detection of hereditary forms of diabetes mellitus based on catamnestic data gathered over a period of many years].
The paper is concerned with an analysis of examination of 414 relatives of the 1st-3rd degree of relationship in 230 families of probands with diabetes mellitus of different types. The frequency of detection of insulin dependent diabetes mellitus (IDDM) among relatives of the 1st degree of relationship in the families of IDDM probands was 1.0 +/- 5.8%. Patients with noninsulin dependent diabetes mellitus (NIDDM) were not detected in these families. The frequency of NIDDM detectability among relatives of the 1st-3rd degree of relationship in the families of NIDDM probands was 38.2-2.5%. IIDM was most common in relatives of the 1st degree of relationship, particularly in women aged 50 to 60 suffering from obesity. A follow-up of relatives with disturbed GTT in the families of NIDDM probands revealed NIDDM in 30% and regression up to normal GTT in 50%.
Golovenko
S A
SA
D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D005500:Follow-Up Studies; D008297:Male; D013997:Time Factors
Vyiavliaemost' nasledstvennykh form sakharnogo diabeta po materialam mnogoletnego katamneza.