Morphometric changes in sympathetic nerve fibres in diabetes.
A morphometric study was carried out on electron micrographs of lumbar sympathetic nerve fibres surgically removed from 12 patients with arteriosclerosis obliterans: 4 diabetics, 4 non-diabetics and 4 subjects with glucose intolerance. In patients with diabetes and glucose intolerance a significant decrease in the percent area fraction of unmyelinated axons and an increase in the percent area fraction of the endoneurial space were demonstrated.
Institute of Morbid Anatomy, University of Modena, Italy.
A
A
Maiorana
V
V
Cavallari
M C
MC
Maiorana
R A
RA
Fano
S
S
Scimone
C
C
Sannicola
D000368:Aged; D001369:Axons / Q000648:ultrastructure; D003920:Diabetes Mellitus / Q000473:pathology*; D005951:Glucose Tolerance Test; D006801:Humans; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000473:pathology* / Q000648:ultrastructure; D012016:Reference Values; D013564:Sympathetic Nervous System / Q000473:pathology*