Family (genetic) studies in neurotic depression.
Neurotic depression may be defined as a depression that occurs in the context of a long standing history of personality difficulties or neurotic symptoms. Two types of conditions fit this definition: (1) depressions secondary to personality disorder, neuroses or substance abuse; and (2) primary depressions with a family history of alcoholism. Depressions so defined show familial relationships with secondary depression, anxiety disorders, alcoholism, and depressions with personality disorders. The data suggest that these cluster in the same family and are related to the definition of neurotic depression given above. Whether these familial relationships are genetic awaits further research.
Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242.
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Winokur
D000275:Adjustment Disorders / Q000235:genetics; D000437:Alcoholism / Q000235:genetics; D001008:Anxiety Disorders / Q000235:genetics; D001714:Bipolar Disorder / Q000235:genetics; D003866:Depressive Disorder / Q000235:genetics*; D004200:Diseases in Twins; D006801:Humans; D010554:Personality Disorders / Q000235:genetics; D012307:Risk Factors