Plasma and skeletal muscle electrolytes in patients on long-term diuretic therapy for arterial hypertension and/or congestive heart failure.
Investigations regarding plasma and skeletal muscle electrolytes were carried out in 537 patients on long-term diuretic treatment (greater than 1 year) for arterial hypertension (n = 240) and/or congestive heart failure (n = 297). In both groups there were significant decreases in both plasma and skeletal muscle K and Mg, while the muscle Na values as well as the total and extracellular water content of skeletal muscle were increased.
Department of Internal Medicine, University of Umeå, Sweden.
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Dyckner
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Wester
D000368:Aged; D001581:Benzothiadiazines; D001834:Body Water / Q000378:metabolism; D004232:Diuretics; D004573:Electrolytes / Q000378:metabolism*; D005110:Extracellular Space / Q000378:metabolism; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism*; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors
D001581:Benzothiadiazines; D004232:Diuretics; D004573:Electrolytes; D049993:Sodium Chloride Symporter Inhibitors