The effect of collagen and indomethacin on inflamed dental pulp wounds of baboon teeth.
Following the induction of experimental pulpitis in baboon teeth, calf skin collagen, indomethacin, or zinc oxide-eugenol was used to dress exposed dental pulp wounds in selected teeth. The teeth were extracted after 7, 35, and 90 days fixed in formalin, and processed, for histopathologic examination. The inflammatory response to zinc oxide-eugenol remained moderate throughout the experiment, whereas the inflammatory response to indomethacin and collagen was present from the outset and became progressively more severe, especially with collagen. The amount of irritation dentin production, however, was greater in those dental pulps dressed with collagen and indomethacin.
College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
B R
BR
Oguntebi
M S
MS
Dover
C J
CJ
Franklin
A S
AS
Tuwaijri
D000818:Animals; D003094:Collagen / Q000627:therapeutic use*; D003782:Dental Pulp / Q000098:blood supply; D003790:Dental Pulp Necrosis / Q000473:pathology; D003809:Dentin, Secondary / Q000473:pathology; D007213:Indomethacin / Q000627:therapeutic use*; D010215:Papio; D011671:Pulpitis / Q000188:drug therapy* / Q000473:pathology; D015035:Zinc Oxide-Eugenol Cement / Q000627:therapeutic use
D015035:Zinc Oxide-Eugenol Cement; D003094:Collagen; D007213:Indomethacin