The variable interdependence of amplitude and implicit-time in PIII, b-wave and optic-nerve responses of the cat.
Amplitude and implicit-times of responses representing different retinal layers (PIII, b-wave and optic-nerve response) were measured in electrophysiological recordings from isolated, arterially perfused cat eyes. The amplitude of these potentials was found to saturate at lower stimulus irradiances than the implicit-time in dark-adapted eyes. Light adaptation had a strong effect on the amplitudes, whereas the implicit-times were altered only slightly. Similar results were obtained in double-flash experiments. The injection of phosphodiesterase inhibiting drugs had different effects on amplitude, latency and implicit-time.
Laboratories of the Max Planck Institute for Physiological and Clinical Research (Bad Nauheim), University Eye Hospital, Munich, West Germany.
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Schneider
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Zrenner
D000200:Action Potentials / Q000187:drug effects; D000221:Adaptation, Ocular; D000818:Animals; D002415:Cats; D004307:Dose-Response Relationship, Radiation; D004596:Electroretinography; D007093:Imidazoles / Q000494:pharmacology; D009900:Optic Nerve / Q000502:physiology*; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology; D010775:Photic Stimulation; D012160:Retina / Q000502:physiology*; D013997:Time Factors
D007093:Imidazoles; D010726:Phosphodiesterase Inhibitors; C029758:sulmazole