[Suppression of the dorsal root potentials of the cat spinal cord by manganese and cobalt ions].
In anesthetized spinal cats, perfusion of lumbosacral spinal cord with artificial CSF containing manganese (1.5-3.0 Mm/l) or cobalt (6.0 mM/l) ions, led to reversible suppression of negative dorsal root potentials (DRP), induced by stimulation of ipsilateral hindlimbs' afferent nerves. The depression of the DRP proceeded in connection with the depression of presynaptic inhibition of extensor monosynaptic reflexes induced with impulse volleys in the group I flexor muscle afferents. The depression of inhibition was not associated with changes in amplitudes of testing monosynaptic reflexes. The DRP is concluded to have a synaptic origin.
D A
DA
Polikarpova
Iu S
IuS
Sverdlov
D000818:Animals; D002415:Cats; D003035:Cobalt / Q000494:pharmacology*; D003655:Decerebrate State / Q000503:physiopathology; D005727:Ganglia, Spinal / Q000187:drug effects* / Q000502:physiology; D008345:Manganese / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects; D009433:Neural Inhibition / Q000187:drug effects*; D010477:Perfusion; D012023:Reflex, Monosynaptic / Q000187:drug effects; D013116:Spinal Cord / Q000187:drug effects* / Q000502:physiology
D003035:Cobalt; D008345:Manganese
Ugnetenie potentsialov dorsal'nykh koreshkov spinnogo kozga koshki ionami margantsa i kobal'ta.