Use of high-density fluorosilicone oil in open-sky vitrectomy.
During prolonged open-sky vitrectomy, fluid accumulates in the suprachoroidal and subretinal spaces and the resultant ballooning of the choroid and of the retina interferes with the surgery. Fluorosilicone oil (polymethyl-3,3,3-trifluoropropylsiloxane) with a specific gravity of 1.28 was tested for use as a temporary vitreous substitute during open-sky vitrectomy. After open-sky vitrectomy and bullous retinal detachment in pigmented rabbits, fluorosilicone oil flattened the retina completely in nine of nine eyes, whereas 1% sodium hyaluronate solution flattened the retina completely in only four of nine eyes. The flattening effect of fluorosilicone oil on the retina was also better than that of 1% sodium hyaluronate in an experiment with retinal detachment and giant retinal tear after open-sky vitrectomy.
Chung
H
H
Eye Research Institute of Retina Foundation, Retina Associates, Boston, MA 02114.
Acosta
J
J
Refojo
M F
MF
Tolentino
F I
FI
D000818:Animals; D004129:Dimethylpolysiloxanes / Q000008:administration & dosage*; D006820:Hyaluronic Acid / Q000008:administration & dosage; D011817:Rabbits; D012163:Retinal Detachment / Q000601:surgery*; D012167:Retinal Perforations / Q000601:surgery*; D012827:Silicone Oils; D012828:Silicones / Q000008:administration & dosage*; D014821:Vitrectomy / Q000379:methods*
D004129:Dimethylpolysiloxanes; D012827:Silicone Oils; D012828:Silicones; C049525:polymethyl-3,3,3-trifluoropropylsiloxane; D006820:Hyaluronic Acid