[Functional disorders and structural changes in the liver in Amanita phalloides poisoning].
The liver functional disorders and structural changes were studied in 17 patients (children 6, adults 11, 4 to 70 years of age) with phalloidine intoxication. The clinical course of this severe and lethal exogenic intoxication, its characteristic clinical and laboratory features are discussed in relation to the morphological changes of the liver. The structural changes are similar in all patients independently of their age and the time of death. They are presented by fatty degeneration, acute toxic liver dystrophy and centrilobular necroses. These changes are produced by the specific action of the phalloidine toxins on the liver.
Khubenova
A
A
Zagurov
G
G
Vasilev
Kh
Kh
D000293:Adolescent; D000328:Adult; D000368:Aged; D000545:Amanita; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000503:physiopathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008875:Middle Aged; D009145:Mushroom Poisoning / Q000503:physiopathology*; D010590:Phalloidine / Q000506:poisoning
D010590:Phalloidine
Funktsionalni smushteniia i strukturni izmeneniia v cherniia drob pri faloidna gŭbna intoksikatsiia.