Difference in learning and retention by Albino-Swiss mice. Part 5. Effect of some antidepressants.
According to the methods described earlier (1), the effect of some antidepressants on memory retention in "good" and "poor" learning mice was studied. The present study indicates that several antidepressants have different activity on memory retrieval of the two subtypes of animals, which is directly responsible for the results here reported. In general terms, the data obtained show that, in addition to the classical antidepressant activity, some derivatives may exert a behavioral disinhibition.
Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.
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Valzelli
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Skorupska
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Kozak
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Banfi
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001362:Avoidance Learning / Q000187:drug effects*; D001522:Behavior, Animal / Q000187:drug effects; D008297:Male; D008568:Memory / Q000187:drug effects*; D051379:Mice; D012153:Retention, Psychology / Q000187:drug effects*
D000928:Antidepressive Agents