Influence of subunit composition of rabbit liver ferritin on its clearance from plasma.
1. Purified rabbit liver ferritin was separated into fractions composed of 87% light molecular weight, and 72% high molecular weight subunits. 2. Radiolabeled ferritin fractions, injected intravenously into rabbits, showed no differences in clearance kinetics. 3. Differences found in ferritin clearance from plasma do not depend on the subunit composition of different molecular species.
Department of Haematology, University Hospital Utrecht, The Netherlands.
E J
EJ
Frenkel
B
B
van den Beld
J J
JJ
Marx
D000818:Animals; D002846:Chromatography, Affinity; D005293:Ferritins / Q000097:blood* / Q000302:isolation & purification; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D046911:Macromolecular Substances; D008970:Molecular Weight; D011817:Rabbits
D046911:Macromolecular Substances; D005293:Ferritins