Carbamazepine as therapy for psychiatric sequelae of herpes simplex encephalitis.
We have presented a case of herpes simplex encephalitis that is interesting in that seizure activity was detected in mesial temporal structures, without manifestations of seizure activity except for severe emotional lability with explosive emotional outbursts. Response to carbamazepine (Tegretol) included marked reduction in EEG-detected seizure activity and in the frequency of emotional outbursts, extending to one year after treatment.
Department of Neuropsychiatry and Behavioral Science, University of South Carolina School of Medicine, Columbia, SC.
A D
AD
Vallini
R L
RL
Burns
D002220:Carbamazepine / Q000627:therapeutic use*; D004569:Electroencephalography; D004660:Encephalitis / Q000150:complications*; D006561:Herpes Simplex / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000209:etiology; D012640:Seizures / Q000188:drug therapy* / Q000209:etiology
D002220:Carbamazepine