Biological properties of preserved human dura mater grafts from different-age donors, tested in xenogenic system of transplantation.
Selected biological properties of human mater grafts obtained from different-age donors and preserved with two methods were tested in a xenogenic system of transplantation. The Regional Lymph Node Blastic Cell Reaction Test revealed relatively low immunogenicity of the material. Microscopic analysis showed that trypsinized grafts are rebuilt at a slower rate and evoke less local reaction than the ethanol-stabilized grafts. No influence of the donors' age on immunogenicity and local reaction after transplantation was observed.
Komender
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Department of Transplantology, Institute of Biostructure Medical Academy, Warsaw.
Lesiak-Cyganowska
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D000328:Adult; D000818:Animals; D002648:Child; D004388:Dura Mater / Q000033:anatomy & histology / Q000276:immunology / Q000637:transplantation*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D014181:Transplantation Immunology; D014183:Transplantation, Heterologous