[Participation of the goblet cells of the small intestine in the excretion of Fe, Zn and Pb cations].
A comparative study of the excess of Zn, Fe and Pb on the amount of goblet cells (GC) and localization of these cations in the chick small intestine epithelium was carried out. In chicks with additional dose of Zn (2 g/kg) and Pb (0.2 g/kg), compared to control chicks the amount of GC in the epithelium of various intestinal parts increased by 1.5-1.8 times. Under a high dose of Pb (2.0 g/kg), the amount of GC increased by 3-4 times, and degenerative changes in the epithelium were observed. A histochemical electron microscopical study of duodenal sections revealed an accumulation of Fe, Zn and Pb within GC and in their excretion, in addition to brush border and glycocalyx. The involvement of intestinal GC in cation excretion is proven.
Bauman
V K
VK
Gaĭlite
B E
BE
Kalntsiema
V Kh
VKh
D000818:Animals; D002452:Cell Count / Q000187:drug effects; D002645:Chickens; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D006651:Histocytochemistry; D007421:Intestine, Small / Q000166:cytology / Q000378:metabolism*; D007501:Iron / Q000008:administration & dosage / Q000378:metabolism*; D007854:Lead / Q000008:administration & dosage / Q000378:metabolism*; D008854:Microscopy, Electron; D015032:Zinc / Q000008:administration & dosage / Q000378:metabolism*
D007854:Lead; D007501:Iron; D015032:Zinc
Uchastie bokalovidnykh kletok tonkogo kishechnika v ékskretsii kationov Fe, Zn i Pb.