Configurational entropy of native proteins.
Simulations of the residual configurational entropy of a protein in the native state suggest that it is nearly an order of magnitude larger than the entropy of denaturation. The implications of this result are discussed.
Karplus
M
M
Department of Chemistry, Harvard University, Cambridge, Massachusetts 02138.
Ichiye
T
T
Pettitt
B M
BM
D008433:Mathematics; D011487:Protein Conformation; D011506:Proteins; D013816:Thermodynamics
D011506:Proteins