Hypothermia in Hodgkin's disease after exploratory laparotomy.
Hypothermia is a rare complication of unknown origin in Hodgkin's disease which has been reported after the administration of antineoplastic agents, chlorpromazine and paracetamol. We report a highly febrile patient with stage IV-B Hodgkin's disease of mixed cellularity type who underwent exploratory laparotomy. Because of suspected septic shock high-dose prednisolone was given during surgery. Postoperatively the patient's body temperature fell progressively to 32.9 degrees C and remained at less then 35.5 degrees C for the following 5 days. There seems to be some functional disorder of thermoregulation in Hodgkin's disease. Physical factors during surgery or certain drugs, especially cytotoxics, corticosteroids, anesthetics or antipyretics may lead to prolonged hypothermia.
Medizinische Universitätsklinik, Universität Wien.
M
M
Jung
R
R
Koppensteiner
W
W
Graninger
H W
HW
Appel
F
F
Lackner
D001833:Body Temperature Regulation / Q000187:drug effects; D004177:Dipyrone / Q000008:administration & dosage; D006689:Hodgkin Disease / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007035:Hypothermia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000209:etiology*; D011239:Prednisolone / Q000008:administration & dosage
D004177:Dipyrone; D011239:Prednisolone