[Apoprotein E (apo E) phenotype and serum lipids in diabetics].
Apo E isoforms have been determined among diabetics. The allele distribution epsilon 2, epsilon 3 and epsilon 4 does not differ from the control population. Diabetics with epsilon 2 allele have increased serum triglycerides compared to diabetics with epsilon 3 and epsilon 4 alleles. In diabetics with E2/2 phenotype both serum cholesterol and serum triglycerides are elevated. The phenotype of apoprotein E does influence serum lipids in diabetics.
James
R W
RW
Division de diabétologie, Hôpital cantonal universitaire, Genève.
Voliotis
C
C
Grab
B
B
Pometta
D
D
D000483:Alleles; D001057:Apolipoproteins E / Q000097:blood / Q000235:genetics*; D008076:Cholesterol, HDL / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood*; D006801:Humans; D008079:Lipoproteins, VLDL / Q000097:blood; D010641:Phenotype; D014280:Triglycerides / Q000097:blood
D001057:Apolipoproteins E; D008076:Cholesterol, HDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides
Phénotypes de l'apoprotéine E (apo E) et lipides sériques des diabétiques.