IR-Met and IR-Leu enkephalin content in the axolotl brain (Ambystoma mexicanum).
The peptides met- and leu-enkephalin were identified in the telencephalon, rombencephalon, diencephalon and hypophysis of Ambystoma mexicanum brain by radioimmunoassay procedure. The met-enkephalin was the predominant peptide present in the axolotl brain in contrast with leu-enkephalin, except in the hypophysis where the ratio MET/LEU was 2.2/l. The clear differences in the concentration between enkephalins through a submammalian brain species as Ambystoma genus and the possibility that leu-enkephalin is derived exclusively from a precursor like prodynorphin offers an excellent model for the opioids biosynthetic processes.
Asai
M
M
División de Neurociencias, Instituto Mexicano de Psiquiatría, San Lorenzo Huipulco.
Cano
A
A
Talavera
E
E
Zubieta
M
M
D000558:Ambystoma mexicanum; D000818:Animals; D001923:Brain Chemistry; D004743:Enkephalin, Leucine / Q000032:analysis*; D004744:Enkephalin, Methionine / Q000032:analysis*
D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine