Defense reactions by larvae of Aedes aegypti during infection by the aquatic fungus Lagenidium giganteum (Oomycete).
The adherence of zoospores of Lagenidium giganteum to the cuticle of mosquito larvae is the initial step in the infection process. Subsequently, a germ tube penetrates the integument, inducing a rapid melanization of the injured cuticle and epidermis. After entering the hemocoel the developing hyphae are occasionally encapsulated locally. This process is slow (6 to 12 h postincubation) and most frequently cell-free, although it can be mediated by circulating hemocytes. Sporadic hemocyte mediation of the humoral encapsulation process in larval stages of Culicidae adds a previously unreported dimension to this unusual type of defense reaction. The defense reactions of larvae of Aedes aegypti were ineffective against observed infection by Lagenidium giganteum.
Unité de Lutte biologique contre les Insectes, Institut Pasteur, Paris, France.
P T
PT
Brey
R A
RA
Lebrun
B
B
Papierok
H
H
Ohayon
S
S
Vennavalli
J
J
Hafez
D000330:Aedes / Q000469:parasitology*; D000818:Animals; D008411:Chytridiomycota / Q000502:physiology*; D004817:Epidermis / Q000648:ultrastructure; D006790:Host-Parasite Interactions; D007814:Larva / Q000166:cytology / Q000502:physiology*; D008854:Microscopy, Electron; D009868:Oomycetes / Q000502:physiology*