[The effect of vitamin K on the activity of glycolysis and pentose phosphate cycle enzymes].
Effect of naphthoquinone levels on the activity of enzymes involved in glycolysis and pentose phosphate cycles was studied in male rats. Under conditions of primary and secondary K-avitaminosis the enzymatic activity, limiting these cycles, (aldolase of fructose-1,6-diphosphate, glucose phosphate isomerase and glucose-6-phosphate dehydrogenase) was increased, while the mitochondrial glutamate dehydrogenase activity was decreased. As a result of metabolic transformations under conditions of K-avitaminosis (primary and secondary) concentration of DNA in the animal tissues was lowered.
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Lider
D000818:Animals; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism; D005956:Glucose-6-Phosphate Isomerase / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006019:Glycolysis / Q000187:drug effects*; D008297:Male; D010427:Pentose Phosphate Pathway / Q000187:drug effects*; D051381:Rats; D014812:Vitamin K / Q000494:pharmacology*; D014813:Vitamin K Deficiency / Q000201:enzymology / Q000378:metabolism
D014812:Vitamin K; D005954:Glucosephosphate Dehydrogenase; D005634:Fructose-Bisphosphate Aldolase; D005956:Glucose-6-Phosphate Isomerase
Vliianie vitamina K na aktivnost' fermentov glikoliza i pentozofosfatnogo tsikla.