[Participation in a simple large-scale randomized trial organized by EORTC through an international computer network].
Case registration and treatment allocation was achieved in a "Simple large-scale trial against colorectal cancer" designed by the European Organization for Research and Treatment of Cancer (EORTC) using an international computer network system VENUS-P. The access to the central computer "EuroCODE" was obtained by simple equipment including ordinary microcomputer, modem and telephone line. Subscription to the KDD data network VENUS-P using a Packet Assembler/Disassembler (PAD) was necessary to connect to the EuroCODE. Intraoperative patient registration and allocation of treatment were possible through this system regardless of the time difference between countries. To organize a large-scale trial as a means to detect moderate but medically worthwhile treatment differences, this method proved to be particularly effective especially for international cooperative studies.
Dept. of Gastroenterological Surgery, Aichi Cancer Center.
J
J
Sakamoto
T
T
Kato
H
H
Nakazato
D003110:Colonic Neoplasms / Q000188:drug therapy; D003195:Computer Communication Networks; D003199:Computer Systems; D004341:Drug Evaluation; D011897:Random Allocation; D012984:Software