[Results of a two-year clinico-morphological study of the natural evolution of diabetic microangiopathy and the efficacy of angioprotective therapy].
The authors analyzed the results of a 2-year study of a course of diabetic microangiopathy on the basis of clinical tests and morphological control over microvessels of skin biopsy specimens from 61 patients with diabetes mellitus, of whom 36 regularly received coronary vasodilators (diamicron, pentoxifylline and dipyridamole). The rest of the patients (25) with diabetes mellitus were taken as controls: 10 patients were with unsatisfactory compensation of diabetes mellitus and 15 with a stable metabolic control. A possibility of stabilization and regression of diabetic microangiopathy during prolonged regular administration of coronary vasodilators was shown.
Velikov
V K
VK
Shubina
O I
OI
Saltykov
B B
BB
Frolova
A I
AI
D000293:Adolescent; D000328:Adult; D000368:Aged; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood / Q000188:drug therapy; D003925:Diabetic Angiopathies / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D004176:Dipyridamole / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010431:Pentoxifylline / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000627:therapeutic use*
D014665:Vasodilator Agents; D004176:Dipyridamole; D010431:Pentoxifylline
Rezul'taty dvukhletnego kliniko-morfologicheskogo nabliudeniia za bol'nymi sakharym diabetom s estestvennym techeniem diabeticheskoĭ mikroangiopathii i poluchavshimi angioprotektivnuiu terapiiu.