[Antiproliferative action of swine leukocyte interferon and of an inhibitor of interferon action].
The results of the study of the antiproliferative effect of swine leukocyte interferon and of an inhibitor of interferon effect in experimental mice with transplanted Krebs-2 ascitic carcinoma cells are presented. The interferon inhibitor exerted antiproliferative effect similar to that of native swine interferon. Combined use of swine interferon and interferon inhibitor did not lead to summation of the antiproliferative effect of these preparations.
Parfenov
V V
VV
Amchenkova
A M
AM
Narovlianskiĭ
A N
AN
Tkach
T A
TA
D000818:Animals; D002287:Carcinoma, Krebs 2 / Q000473:pathology / Q000628:therapy; D002452:Cell Count / Q000187:drug effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D007370:Interferon Type I / Q000037:antagonists & inhibitors* / Q000627:therapeutic use*; D051379:Mice; D009368:Neoplasm Transplantation; D013552:Swine; D013997:Time Factors
D007370:Interferon Type I
Antiproliferativnoe deĭstvie svinogo leĭkotsitarnogo interferona i ingibitora deĭstviia interferona.