Indium-111 leukocyte accumulation in submandibular gland saliva as a cause for false-positive gut uptake in children.
Unexplained false-positive accumulation of In-111 leukocyte in the gastrointestinal tract has been reported previously. In a pediatric population, uptake in the submandibular gland was noted in 19 of 42 children. This is believed to be a normal finding in children that is not seen in adults. In some of these 19 children, unexplained gastrointestinal activity was also noted. Saliva from a patient with false-positive gastrointestinal uptake and positive submandibular activity was positive for In-111. One suggested cause of unexplained gut activity may be secondary to swallowed activity in the saliva from the normal submandibular activity in children.
Department of Radiology, University of Arkansas for Medical Sciences, Little Rock.
S L
SL
Williamson
M R
MR
Williamson
J J
JJ
Seibert
C M
CM
Boyd
T
T
Latture
D002648:Child; D004064:Digestive System / Q000000981:diagnostic imaging*; D005189:False Positive Reactions; D006801:Humans; D007205:Indium Radioisotopes; D007962:Leukocytes; D011877:Radionuclide Imaging; D012463:Saliva / Q000378:metabolism*; D013363:Submandibular Gland / Q000000981:diagnostic imaging*
D007205:Indium Radioisotopes