Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution.
Twenty-four male mice, belonging to 8 different inbred strains, were tested in an 8-arm radial maze. Clear strain differences were found for performance on the third day of training, which correlated very strongly with the size of the hippocampal intra- and infrapy ramidal mossy fibre (iip-MF) terminal fields. These results, combined with those from earlier experiments, indicate that genetic variations of the iip-MF projection influence processes that determine behavioural abilities of mice.
Institut für Humangenetik und Anthropologie, Universität Heidelberg, F.R.G.
W E
WE
Crusio
H
H
Schwegler
H P
HP
Lipp
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D006624:Hippocampus / Q000033:anatomy & histology*; D008297:Male; D051379:Mice; D009412:Nerve Fibers / Q000033:anatomy & histology*; D051381:Rats; D011919:Rats, Inbred Strains