Esophageal candidiasis associated with beclomethasone dipropionate aerosol therapy.
A 23-year-old woman with asthma developed severe heartburn while using beclomethasone dipropionate. Esophageal candidiasis was diagnosed on endoscopy and confirmed by biopsy. Subsequent studies revealed mild hypogammaglobulinemia and mild impairment of neutrophil candidacidal activity, the significance of which is unknown. Esophageal candidiasis associated with the use of inhaled beclomethasone has not been previously reported.
Kesten
S
S
Division of Respirology and Critical Care Medicine, Wellesley Hospital, Toronto, Ontario, Canada.
Hyland
R H
RH
Pruzanski
W R
WR
Kortan
P P
PP
D000328:Adult; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy; D001507:Beclomethasone / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D002177:Candidiasis / Q000139:chemically induced* / Q000382:microbiology; D004935:Esophageal Diseases / Q000139:chemically induced* / Q000382:microbiology; D005260:Female; D006801:Humans
D000336:Aerosols; D001507:Beclomethasone