[Effects of parenterally administered dicarboxylic amino acids and their amides on the secretory function of the stomach].
The effect of dicarboxylic amino acids and their amides on gastric secretion stimulated by sham-feeding (100 g of raw meat), as well as of amides of dicarboxylic amino acids on the gastric secretory function was studied in 119 tests on 8 dogs with gastric fistulas according to Basov. The tests were started 16-18 h after feeding under neutral or alkaline reactions of gastric excretion. The tests demonstrated that dicarboxylic amino acids inhibited gastric secretion induced by sham-feeding. It was shown that dicarboxylic amino acid amines, in contrast to these amino acids, did not inhibit gastric secretion induced by sham-feeding. On the contrary, asparagine and glutamine administered into the blood are capable of inducing gastric secretion, per se.
Ignatenko
L G
LG
Vasilevskaia
L S
LS
Poriadkov
L F
LF
D000409:Alanine / Q000008:administration & dosage / Q000494:pharmacology; D000600:Amino Acids, Dicarboxylic / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D001216:Asparagine / Q000008:administration & dosage / Q000494:pharmacology; D004285:Dogs; D004435:Eating; D005750:Gastric Juice / Q000378:metabolism*; D005973:Glutamine / Q000008:administration & dosage / Q000494:pharmacology; D007262:Infusions, Intravenous
D000600:Amino Acids, Dicarboxylic; D005973:Glutamine; D001216:Asparagine; D000409:Alanine
Vliianie parental'no vvedennykh dikarbonovykh aminokislot i ikh amidov na sekretornuiu funktsiiu zheludka.