Neuronal activity in nuclei pontis and reticularis tegmenti pontis related to forelimb movements of the monkey.
The activity of the pontine nucleus (PN) neuron was recorded in 3 monkeys moving a handle alternately from start to target zones in a simple extension-flexion movement at the wrist. Of 73 PN neurons related to the task, 44 were related to movement, 19 to handle holding and 5 to both movement and holding of the handle. Of the 44 movement-related neurons, 16 were related to flexion, 22 to extension, and 6 to both. In 37 of 54 analyzed movements of the PN neurons which were related to movements, or to both movements and handle holding, the change of the activity occurred before the movement. However, in most of these cases (24/37), discharge occurred less than 100 ms earlier than the start of the movement. In the remaining one-third of movements (17/54), neurons discharged after the onset of the movement. Locations of the 73 neurons were histologically verified in the pontine nucleus. Somewhat similar observations were made of 14 cells located in the nucleus reticularis tegmenti pontis (NRTP). Considering that the majority of movement-related PN and NRTP neurons discharged immediately before or even after the onset of movement, these neurons may play a role in the execution of movement, at least of a simple movement, rather than in the initiation or planning of movement.
Department of Neurophysiology, Kyoto University, Inuyama City, Japan.
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Matsunami
D000818:Animals; D002531:Cerebellum / Q000502:physiology; D004558:Electric Stimulation; D004594:Electrophysiology; D005552:Forelimb; D008251:Macaca; D008253:Macaca mulatta; D009068:Movement; D009474:Neurons / Q000502:physiology*; D011149:Pons / Q000166:cytology / Q000502:physiology*