Influence of dietary lipids and linoleic acid amounts on fatty acid content and composition of pig serum lipoproteins.
The effects of hyperlipidic polyunsaturated fat diets (PF) and saturated fat diets (SF) versus control diet (CO) on total lipid, phospholipid (PL) and cholesteryl ester (CE) content and composition of pig serum lipoproteins were studied in Large White pigs who first underwent a PF period for 14 days followed by a CO period and third a SF feeding during a fortnight. PF and SF diets induced an increase of linoleic acid in serum total lipids, especially in HDL fraction; this increase in CE and PL involved a reverse change of oleic acid. The modifications induced by the amounts of dietary linoleic acid could be explained by an alteration of LCAT activity. The fatty acid pattern of PL which constitute the LCAT substrate lead to an enrichment of cholesterol linoleate.
Persegol
L
L
Laboratoire de Physiologie de la Nutrition, UA CNRS 273, Faculté des Sciences Mirande, Dijon.
Paris
R
R
D000818:Animals; D002788:Cholesterol Esters / Q000097:blood; D004041:Dietary Fats / Q000494:pharmacology*; D005224:Fats, Unsaturated / Q000494:pharmacology; D005227:Fatty Acids / Q000097:blood*; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000097:blood / Q000494:pharmacology*; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D010743:Phospholipids / Q000097:blood; D013552:Swine
D002788:Cholesterol Esters; D004041:Dietary Fats; D005224:Fats, Unsaturated; D005227:Fatty Acids; D008041:Linoleic Acids; D008055:Lipids; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D010743:Phospholipids; D019787:Linoleic Acid