[Pharmacokinetics of sulfalene and sulfadimethoxine in chronic pyelonephritis patients].
Accelerated elimination of sulfalen was observed in patients with chronic pyelonephritis, unimpaired glomerular filtration and lowered tubular reabsorption. This was due to lowered sulfalen reabsorption in the kidney tubules. Sulfadimethoxine pharmacokinetics in such patients was not significantly changed.
V I
VI
Bobrov
V A
VA
Briker
G A
GA
Glezer
V P
VP
Iakovlev
D000042:Absorption; D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007684:Kidney Tubules / Q000378:metabolism; D008297:Male; D011704:Pyelonephritis / Q000378:metabolism*; D013412:Sulfadimethoxine / Q000493:pharmacokinetics*; D013415:Sulfalene / Q000493:pharmacokinetics*; D013424:Sulfanilamides / Q000493:pharmacokinetics*; D013607:Tablets; D013997:Time Factors
D013424:Sulfanilamides; D013607:Tablets; D013412:Sulfadimethoxine; D013415:Sulfalene
Farmakokinetika sul'falena i sul'fadimetoksina u bol'nykh khronicheskim pielonefritom.