Restraint induced stress elicits acute-phase response in rabbits.
We investigated whether a restraint induced stress elicits an acute-phase response which includes changes in the plasma trace metals, fibrinogen and the circulating leucocyte count. The present results showed that restraint-stress induces significant increases in the plasma concentrations of copper and fibrinogen and decreases in those of iron and zinc in rabbits, indicating that some of acute-phase response are produced without fever mediated by endogenous pyrogen.
Department of Physiology, Yamaguchi University School of Medicine, Ube, Japan.
A
A
Morimoto
T
T
Watanabe
T
T
Myogin
N
N
Murakami
D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D003300:Copper / Q000097:blood; D005340:Fibrinogen / Q000378:metabolism; D066298:In Vitro Techniques; D007501:Iron / Q000097:blood; D008297:Male; D011817:Rabbits; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000503:physiopathology*; D015032:Zinc / Q000097:blood
D003300:Copper; D005340:Fibrinogen; D007501:Iron; D015032:Zinc