[Familial distal progressive spinal amyotrophy with asymmetry of the lower limbs].
Two cases of spinal muscular atrophy, localized on the lower limbs and strictly unilateral, in two half brothers, are reported. Such a distribution of clinical changes and such a hereditary transmission appear to be unusual in hereditary motor-neuronopathies. A recessive heterotopic transmission may be suspected. To our knowledge, it has been reported in Kennedy's disease only.
Service de Neurologie B, C.H.R. Angers.
C
C
Nedelec
F
F
Dubas
J L
JL
Truelle
F
F
Pouplard
F
F
Delestre
I
I
Penisson-Besnier
D000293:Adolescent; D000328:Adult; D006801:Humans; D007870:Leg Length Inequality / Q000235:genetics*; D008297:Male; D009134:Muscular Atrophy, Spinal / Q000175:diagnosis / Q000235:genetics*; D010375:Pedigree; D014960:X Chromosome
Amyotrophie spinale progressive distale et asymétrique des membres inférieurs à caractère familial.