Lack of validity of the KDI Quik Test Drug Screen for detection of benzoylecgonine in urine.
The validity of the Quik Test Drug Screen for detection of benzoylecgonine was assessed by testing, in random order under blind conditions, 50 aliquots of drug-free urine and 50 aliquots of urine containing 6000 ng/mL of benzoylecgonine. Three independent readers of the test results had an average overall accuracy of only 50%. Each specimen also was tested by TDx assay for cocaine metabolite. In contrast to the Quik Test, the TDx assay was completely accurate. The false positive and false negative rates of the Quik Test Drug Screen for benzoylecgonine in urine were found to be unacceptably high, and its use in urine testing for cocaine abuse is not recommended.
Addiction Research Center, NIDA, Baltimore, Maryland 21224.
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Menchen
D003042:Cocaine / Q000031:analogs & derivatives* / Q000652:urine; D005069:Evaluation Studies as Topic; D006801:Humans; D008297:Male; D011933:Reagent Kits, Diagnostic
D011933:Reagent Kits, Diagnostic; C005618:benzoylecgonine; D003042:Cocaine