Single-dose cefotaxime intramuscularly cures gonococcal ophthalmia neonatorum.
Nine neonates with culture proved gonococcal ophthalmia neonatorum were treated with a single intramuscular injection of 100 mg/kg of cefotaxime without topical antibiotic therapy. Five of the nine strains were penicillinase-producing Neisseria gonorrhoeae. All nine cases were clinically and microbiologically cured, and no side effects were observed.
Department of Paediatrics, Kigali Hospital, Rwanda.
P
P
Lepage
J
J
Bogaerts
P
P
Kestelyn
A
A
Meheus
D002439:Cefotaxime / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D008297:Male; D009878:Ophthalmia Neonatorum / Q000188:drug therapy*
D002439:Cefotaxime