Treatment of phenylketonuria with a formula consisting of low-phenylalanine peptide. A collaborative study.
A method of preparation of a more palatable therapeutic formula for phenylketonuria (PKU), consisting of low-phenylalanine peptide (LPP), was reported. There were no adverse effects and, in fact, there was a reduced frequency of diarrhea in patients who received LPP formula for more than 6 months. The LPP formula can be used not only as a more palatable therapeutic milk for PKU, but also as an ingredient to make more palatable foods of low-phenylalanine content.
Department of Pediatrics, Nihon University School of Medicine, Tokyo, Japan.
T
T
Kitagawa
M
M
Owada
K
K
Aoki
S
S
Arai
T
T
Oura
I
I
Matsuda
Y
Y
Igarashi
K
K
Tada
S
S
Katayama
W
W
Hashida
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005526:Food, Formulated; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D010455:Peptides; D010649:Phenylalanine / Q000097:blood; D010661:Phenylketonurias / Q000097:blood / Q000178:diet therapy*; D011247:Pregnancy; D011379:Prognosis; D013649:Taste
D010455:Peptides; D010649:Phenylalanine