Effects of medial frontal cortex lesions on DRL performance in rats.
Rats with medial frontal cortical lesions (MFC) and control animals with sham operations were tested on an ascending series of 8 DRL schedules of reinforcement ranging from 5 to 70 seconds. Rats with MFC lesions did not differ from the control group in performance when response rate, responses per reinforcement and efficiency were analyzed. These results indicate that deficits in "response inhibition" often displayed by rats with MFC lesions may be task-specific.
Department of Psychology, Washington University, St. Louis, MO 63130.
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D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D003216:Conditioning, Operant / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology*; D008297:Male; D051381:Rats; D012055:Reinforcement Schedule; D013997:Time Factors