Binding capacity: cooperativity and buffering in biopolymers.
The group of linkage potentials resulting from the energy of a physicochemical system expressed per mol of a reference component, say a polyfunctional macromolecule, leads to the concept of binding capacity. This concept applies equally to both chemical and physical ligands and opens the way to consideration of higher-order linkage relationships. It provides a means of exploring the consequences of thermodynamic stability on generalized binding phenomena in biopolymers.
Di Cera
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Department of Chemistry and Biochemistry, University of Colorado, Boulder 80309-0215.
Gill
S J
SJ
Wyman
J
J
D001704:Biopolymers; D004355:Drug Stability; D008024:Ligands; D046911:Macromolecular Substances; D008433:Mathematics; D008962:Models, Theoretical; D013816:Thermodynamics
D001704:Biopolymers; D008024:Ligands; D046911:Macromolecular Substances