Telomeric association: another characteristic of cancer chromosomes?
Telomeric associations between single chromatids and double chromatids of nonhomologous normal human chromosomes and altered markers were observed in two morphologically distinct squamous-cell carcinoma lines derived from a surgical specimen. Chromosomes 2, 3, 5, and 16 were associated by their telomeric ends more frequently than other chromosomes.
Pathak
S
S
Department of Cell Biology, University of Texas, M.D. Anderson Hospital and Tumor Institute, Houston 77030.
Wang
Z
Z
Dhaliwal
M K
MK
Sacks
P C
PC
D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000648:ultrastructure; D002842:Chromatids / Q000648:ultrastructure; D002869:Chromosome Aberrations; D006801:Humans; D008297:Male; D008875:Middle Aged; D014407:Tumor Cells, Cultured