Histopathologic changes in condylomata acuminata after application of podophyllum.
The histologic changes of podophyllin-treated condylomata acuminata were studied at 24-hour, 48-hour, and 7-day intervals. The 24-hour specimens had scattered individual atypical cells, whereas 48-hour specimens demonstrated small focal areas of atypia. Seven-day specimens exhibited very mild atypia of cells. All treated specimens had inflammation-necrosis ranging from scattered inflammatory cells to degeneration of the squamous epithelium.
Dorsey
K E
KE
Gallagher
R L
RL
Davis
R
R
Rodman
O G
OG
D000287:Administration, Topical; D003218:Condylomata Acuminata / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D005833:Genital Neoplasms, Female / Q000188:drug therapy / Q000473:pathology*; D005834:Genital Neoplasms, Male / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008297:Male; D011033:Podophyllin / Q000627:therapeutic use*
D011033:Podophyllin