Protective effect of irradiated metacercariae of Fasciola gigantica and irradiated cercariae of Schistosoma bovis against fascioliasis in goats.
Sensitisation of goats for eight weeks with metacercariae of Fasciola gigantica gamma-irradiated at 3 kr resulted in significant resistance to an homologous challenge with normal metacercariae. However, serum sorbitol dehydrogenase assay suggested that, whereas little damage was produced by immunising infections, considerable hepatic damage was caused by flukes remaining from challenge infections. On the other hand sensitisation with cercariae of Schistosoma bovis gamma-irradiated at 3 kr did not stimulate any resistance against heterologous challenge with F. gigantica.
Faculty of Veterinary Science, University of Khartoum, Sudan.
A A
AA
el Sanhouri
E M
EM
Haroun
A A
AA
Gameel
H O
HO
Bushara
D000818:Animals; D005209:Fasciola / Q000276:immunology* / Q000528:radiation effects; D005211:Fascioliasis / Q000517:prevention & control / Q000662:veterinary*; D005720:Gamma Rays; D006041:Goats; D007114:Immunization / Q000662:veterinary*; D007064:L-Iditol 2-Dehydrogenase / Q000097:blood; D008099:Liver / Q000201:enzymology / Q000469:parasitology; D008297:Male; D012547:Schistosoma / Q000276:immunology* / Q000528:radiation effects
D007064:L-Iditol 2-Dehydrogenase