Effects of seizure duration on serum TSH concentration after ECT.
Serum thyroid stimulating hormone (TSH) concentrations were measured by a sensitive immunoradiometric assay in 14 patients immediately before and after the first treatment of a course of electroconvulsive therapy (ECT). There was a close correlation (r = +0.70, p less than 0.01) between the increase in TSH concentration 15 min after ECT and the duration of seizure activity as measured by EEG. This observation may help clarify previous contradictory findings on the effects of ECT on TSH concentrations. There was no correlation between the increase in serum TSH concentration and the extent of recovery from depressive illness.
University Department of Psychiatry, Royal Edinburgh Hospital, Scotland.
S
S
Dykes
A I
AI
Scott
S M
SM
Gow
L J
LJ
Whalley
D000368:Aged; D003866:Depressive Disorder / Q000628:therapy*; D004565:Electroconvulsive Therapy; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D012640:Seizures / Q000503:physiopathology*; D013972:Thyrotropin / Q000097:blood*
D013972:Thyrotropin