[The actions and properties of sodium nucleinate used as a pyrogen working standard. 3. Changes in the leukocyte picture of rabbits following intravenous injection of sodium nucleinate].
In rabbits, the i.v. injection of a sodium nucleinate solution, like a solution of bacterial pyrogen administered in the same way, at first induces leucopenia, followed by leucocytosis. The fraction of pseudoeosinophiles increases, while that of lymphocytes decreases.
Dressel
H
H
Institut für Arzneimittelwesen der DDR, Berlin.
D000818:Animals; D004804:Eosinophils / Q000187:drug effects; D007275:Injections, Intravenous; D007958:Leukocyte Count / Q000187:drug effects; D007962:Leukocytes / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects; D009696:Nucleic Acids / Q000494:pharmacology*; D011749:Pyrogens / Q000494:pharmacology*; D011817:Rabbits
D009696:Nucleic Acids; D011749:Pyrogens; C013683:sodium nucleinate
Uber Wirkungen und Eigenschaften des als Pyrogen-Arbeitsstandard verwendeten Natriumnucleinats. 3. Mitteilung: Anderungen des weissen Blutbildes von Kaninchen nach intravenöser Injektion von Natriumnucleinat.