Intramitochondrial compartmentation of progesterone biosynthesis from cholesterol in the human placenta.
Intramitochondrial distribution of the cholesterol side-chain cleavage reaction was investigated in human placental mitochondria. The matrix side of the inner mitochondrial membrane has been found to be most probably side of this reaction.
Boguslawski
W
W
Department of General Chemistry, Medical Academy of Gdańsk, Poland.
D002784:Cholesterol / Q000378:metabolism*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008928:Mitochondria / Q000378:metabolism*; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011284:Pregnenolone / Q000096:biosynthesis; D011374:Progesterone / Q000096:biosynthesis*
D011374:Progesterone; D011284:Pregnenolone; D002784:Cholesterol