[Use of Naja oxiana venom for modulating the adrenergic process].
Specific changes of adrenergic responses to the poison of the Middle Asia cobra were found in the rat isolated small intestine. The changes reminded the action of inhibitors upon enzymes and may be characterized as a partial competitiveless interaction. The poison modulating effect upon adrenergic responses seem to be unrelated to its direct action on adrenoreceptors, but mediated through the effector cell's membrane.
B N
BN
Manukhin
T P
TP
Kichikulova
A T
AT
Berdyeva
D000818:Animals; D004546:Elapid Venoms / Q000494:pharmacology*; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000294:innervation* / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D013564:Sympathetic Nervous System / Q000187:drug effects* / Q000502:physiology
D004546:Elapid Venoms; D009638:Norepinephrine
Ispol'zovanie iada sredneaziatskoĭ kobry dlia moduliatsii adrenergicheskogo protsessa.