[Kaposi disease in an LAV/HTLV-III antibody negative patient at risk for AIDS].
We report on a disseminated variant of Kaposi's sarcoma (M.K.) with a moderate course in a homosexual patient negative for LAV/HTLV-III antibodies. The disease had started at the age of 44 years. Clinical examination proved the patient's good condition. Serological findings revealed numerous former infections. Control investigations for 5 years have not shown any signs of immune deficiency, so far. Morphological investigation (applicable to all forms of M.K.) indicated a reversed differentiation of the vascular connective tissue with ensuing misdifferentiation. Thus, the tumor should be interpreted as an abnormal product of the primary vascular mesenchyme. It is characterized by a synchymal/spongiochymal structure. This view corresponds with older ideas. Recent histochemical and electron microscopical findings do not contradict this conception in any way, but do rather confirm it.
Dermatologische Klinik und Poliklinik der Technischen Universität München.
G
G
Oehlschlaegel
K H
KH
Marquart
R
R
Engst
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D004730:Endothelium, Vascular / Q000473:pathology; D006679:HIV Seropositivity; D006716:Homosexuality; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010412:Penile Neoplasms / Q000473:pathology*; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000473:pathology*; D012867:Skin / Q000473:pathology
Morbus Kaposi bei einem LAV/HTLV-III-Antikörper-negativen AIDS-Risikopatienten.