Adverse reaction to procaine penicillin G in horses.
Adverse reactions to intramuscular injections of procaine penicillin G are reported in 11 horses, five of which died. The clinical findings are presented and suggest central nervous involvement in most cases. Post mortem findings in one horse were consistent with anaphylaxis whereas in other cases the clinical findings, duration of treatment, speed of onset and subsequent completion of treatment supports diagnosis of an acute procaine toxicity syndrome.
Canberra Veterinary Hospital, Lyneham, Australian Capital Territory.
I L
IL
Nielsen
K A
KA
Jacobs
P J
PJ
Huntington
C B
CB
Chapman
K C
KC
Lloyd
D000707:Anaphylaxis / Q000139:chemically induced / Q000662:veterinary; D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000139:chemically induced* / Q000473:pathology; D006736:Horses; D008297:Male; D010400:Penicillin G / Q000009:adverse effects*; D010402:Penicillin G Procaine / Q000009:adverse effects*
D010402:Penicillin G Procaine; D010400:Penicillin G