[Severe and extensive algodystrophies and malignant tumors. Apropos of 4 cases].
The authors report on 4 cases of particularly severe and extensive reflex neurovascular dystrophy, whose clinical course was marked by the onset of a malignant tumor, without any sign of improvement in the reflex neurovascular dystrophy, despite various therapeutic regimens, until the patient's death from malignancy. At this time, the authors compiled a total of 63 case reports (4 of which were reported) and have proposed a classification to differentiate 4 types of disorders in combination according to whether there is a very probable, probable, or possible link or whether the combination is strictly a coincidence. The pathogenic mechanism remains a mystery, when a link is observed; but it never corresponds to criteria to describe a paraneoplastic disorder. Finally, the authors insist on the practical value of detecting this combination, even if due to chance: in order to systematically detect cancer in the presence of any reflex neurovascular dystrophy, and especially to be conscious of a possible reflex neurovascular dystrophy, besides possible metastatic lesions, in the presence of osteoarticular pain present in a patient with cancer. Such a diagnosis, although difficult to realize, has great prognostic and therapeutic interest.
Service de Rhumatologie, HIA Bégin, Saint-Mandé.
P
P
Doury
D
D
Wendling
S
S
Pattin
F
F
Eulry
P
P
Delmaire
P
P
Aboukrat
Y
Y
Rolland
O
O
Leloire
D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000150:complications; D005260:Female; D005528:Foot; D006225:Hand; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D010051:Ovarian Neoplasms / Q000150:complications; D010257:Paraneoplastic Syndromes; D012019:Reflex Sympathetic Dystrophy / Q000209:etiology*; D013274:Stomach Neoplasms / Q000150:complications; D013997:Time Factors
Algodystrophies sévères et extensives et tumeurs malignes. A propos de 4 observations.