Striae albae: a morphological study on the human skin.
Specimens of abdomen skin, comprising alternate areas of striae albae and healthy skin, were removed during surgical lipectomy from multiparous and obese women between the ages of 24 and 53 years. A flattening and thinning of the striae albae surface and the almost complete disappearance of dermal papillae was observed in paraffin and thin sections. The papillary dermis was found to be almost completely replaced by straight bundles of collagen fibres running parallel to the skin surface. Immunofluorescence data revealed in these bundles high positivity for type I collagen. The underlying reticular dermis was also found to contain large densely packed bundles of collagen fibres running parallel to the skin surface. Both papillary and reticular dermis collagen fibres were mainly arranged orthogonally to the main axis of the stria. Furthermore, the density of the collagen fibre bundles and the diameter of the collagen fibrils was found to be greater than that of the clinically healthy skin. A larger number of elastic fibres, which presented an abnormal ultrastructural appearance, were visible in pathological papillary and reticular dermis.
De Pasquale
V
V
Istituto di Anatomia Umana Normale, Università di Bologna, Italy.
Franchi
M
M
Govoni
P
P
Guizzardi
S
S
Raspanti
M
M
Poppi
V
V
Ruggeri
A
A
D000293:Adolescent; D000328:Adult; D003094:Collagen / Q000378:metabolism*; D004549:Elastin / Q000378:metabolism*; D004817:Epidermis / Q000032:analysis / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D012871:Skin Diseases / Q000378:metabolism / Q000473:pathology*
D003094:Collagen; D004549:Elastin