A comparison between Bactec aerobic resin and hypertonic blood culture media.
The presence of antimicrobial agents in patients' blood is thought to represent an important source of false-negative blood cultures. This has led to the incorporation of agents with inhibitory effects on antimicrobial drugs into culture medium. In the present study, Bactec aerobic resin-containing blood culture medium was compared with Bactec hypertonic blood culture medium. 504 patients receiving cytostatic and/or antibiotic treatment were studied. Sensitivity calculations on detection of bacteremia in these patients gave 0.91 for the resin medium and 0.79 for the hypertonic blood culture system and showed a significant difference (p = 0.016). In addition, the resin-containing system more rapidly detected positive cultures than the hypertonic system.
Department of Clinical Microbiology, Orebro Medical Center Hospital, Sweden.
L
L
Sjöberg
H
H
Fredlund
A S
AS
Duberg
D001419:Bacteria / Q000254:growth & development*; D001769:Blood / Q000382:microbiology; D003470:Culture Media; D005188:False Negative Reactions; D006801:Humans; D012116:Resins, Plant; D018805:Sepsis / Q000175:diagnosis*
D003470:Culture Media; D012116:Resins, Plant