Intra-articular bupivacaine for pain relief after arthroscopic surgery of the knee joint in daycase patients.
A randomised double-blind study was conducted to compare the influence on postoperative pain of equal volumes of one of two concentrations of bupivacaine (0.25%, 0.5%), or saline 0.9%, injected into the knee joint after arthroscopy. The results showed that intra-articular bupivacaine had no significant analgesic effect in either concentration. Plasma bupivacaine concentrations were measured 20 minutes after injection in order to determine the extent of systemic absorption.
Mansfield and District General Hospital, Nottinghamshire.
K A
KA
Milligan
M J
MJ
Mowbray
L
L
Mulrooney
P J
PJ
Standen
D000293:Adolescent; D000328:Adult; D000556:Ambulatory Surgical Procedures; D000772:Anesthesia, Local; D001182:Arthroscopy; D002045:Bupivacaine / Q000008:administration & dosage / Q000097:blood; D006801:Humans; D007270:Injections, Intra-Articular; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000628:therapy*
D002045:Bupivacaine