[Age-related structural changes in the stimuli-conducting system of the human heart].
The cardionectors of 32 patients who had died at different ages without clinical or morphological indications of heart disease were examined. The autopsy was performed 8 to 24 h after death. Histochemical and histomorphometric tests were used to detect age-related changes in the conduction system (sino-auricular and AV nodes). The proportion of connective tissue increases in the cardionector and diminishes in the muscle tissue with increasing age, the changes being more pronounced in the sino-auricular than in the AV node. In the age group over 60, for instance, the proportion of connective tissue by volume is over 120% higher, in the sino -auricular node and 90% higher in the AV node than in the age group under 10. The correlation coefficient between age and proportion of connective tissue is also higher in the sino-auricular node (0.65) than in the AV node (0.53).
Lehrstuhl Gerichtsmedizin, der Medizinischen Akademie Sofia, Volksrepublik Bulgarien.
I
I
Buruljanowa
G
G
Wassilew
S
S
Radanov
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D001283:Atrioventricular Node / Q000033:anatomy & histology*; D002648:Child; D002675:Child, Preschool; D006321:Heart / Q000033:anatomy & histology*; D006329:Heart Conduction System / Q000033:anatomy & histology*; D006801:Humans; D007223:Infant; D008875:Middle Aged; D012849:Sinoatrial Node / Q000033:anatomy & histology*
Altersbedingte Strukturveränderungen in dem Reizleitungssystem des menschlichen Herzens.