[Kaposi disease in an LAV/HTLV-III antibody negative patient at risk for AIDS].
We report on a disseminated variant of Kaposi's sarcoma (M.K.) with a moderate course in a homosexual patient negative for LAV/HTLV-III antibodies. The disease had started at the age of 44 years. Clinical examination proved the patient's good condition. Serological findings revealed numerous former infections. Control investigations for 5 years have not shown any signs of immune deficiency, so far. Morphological investigation (applicable to all forms of M.K.) indicated a reversed differentiation of the vascular connective tissue with ensuing misdifferentiation. Thus, the tumor should be interpreted as an abnormal product of the primary vascular mesenchyme. It is characterized by a synchymal/spongiochymal structure. This view corresponds with older ideas. Recent histochemical and electron microscopical findings do not contradict this conception in any way, but do rather confirm it.
Oehlschlaegel
G
G
Dermatologische Klinik und Poliklinik der Technischen Universität München.
Marquart
K H
KH
Engst
R
R
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D004730:Endothelium, Vascular / Q000473:pathology; D006679:HIV Seropositivity; D006716:Homosexuality; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010412:Penile Neoplasms / Q000473:pathology*; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000473:pathology*; D012867:Skin / Q000473:pathology
Morbus Kaposi bei einem LAV/HTLV-III-Antikörper-negativen AIDS-Risikopatienten.