Sublingual lorazepam in childhood serial seizures.
Sublingual lorazepam was successful in controlling serial seizures in ten children. There was both intrasubject and intersubject variability in the effective dose, which ranged from about 0.05 mg/kg to 0.15 mg/kg. Side effects were minimal and consisted of drowsiness, unsteadiness, nausea, and hyperactivity. Sublingual lorazepam is an easy and effective way to treat serial seizures at home.
Section of Pediatric Neurosciences, Children's Hospital of Winnipeg, Manitoba, Canada.
J Y
JY
Yager
S S
SS
Seshia
D000286:Administration, Sublingual; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008140:Lorazepam / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male
D008140:Lorazepam