Changing from oral to depot fluphenazine.
Many of the problems that occur when patients are changed from oral to depot fluphenazine are caused by the high dosages resulting from the formulas used for dose conversion. The authors propose a new method based on recent information on the pharmacokinetics of fluphenazine decanoate, low-dose treatment strategies in schizophrenia, and their own clinical experience.
Department of Psychiatry, Medical College of Pennsylvania at Eastern Pennsylvania Psychiatric Institute, Philadelphia 19129.
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Yadalam
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Simpson
D000284:Administration, Oral; D001835:Body Weight; D004334:Drug Administration Schedule; D005476:Fluphenazine / Q000008:administration & dosage* / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy
C011825:fluphenazine depot; D005476:Fluphenazine