Craniomandibular bone density in the primate as assessed by computed tomography.
Ten normal rhesus monkeys, five juvenile and five adult animals, were analyzed for symmetry in bone density across the cranioskeleton with computed tomography (CT). Fifty contiguous axial CT scans were done using 1.5-mm thick scans between the lower mandibular border and inferior orbital ridge, and 3-mm thick scans from the inferior orbital ridge to the rostral level of insertion of the temporalis muscle. Eleven regions comprising areas of the lower mandibular border, lower ramus, upper ramus with condyle, the coronoid process, the zygomatic arch, and cranial bone were analyzed for symmetry using small regions of interest. Only one region, the condyle, demonstrated a statistically significant difference between the two sides with all other measured sites demonstrating the same bone mineral density bilaterally. Large area analysis of five regions--the lower mandibular border, upper ramus with condyle, the coronoid process, the zygomatic arch, and upper cranium--demonstrated no significant difference in the distribution of CT numbers. This analysis of bilateral distribution of bone density in the primate craniofacial skeleton demonstrates a basic symmetry that can be used to study altered patterns of neuromuscular function and their effects on bone density.
Department of Growth and Development, School of Dentistry, University of California, San Francisco.
A J
AJ
Miller
C E
CE
Cann
I
I
Nielsen
G
G
Roda
D000375:Aging; D000818:Animals; D005147:Facial Bones / Q000000981:diagnostic imaging*; D008253:Macaca mulatta; D008334:Mandible / Q000000981:diagnostic imaging; D008335:Mandibular Condyle / Q000000981:diagnostic imaging; D012886:Skull / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D015050:Zygoma / Q000000981:diagnostic imaging