[Effect of synthetic fragments of thymic peptide hormones on learning and memory processes].
Seven synthetic peptide fragments of thymic hormones were investigated using behavioral and electrophysiological methods. Splenopentin was shown to increase markedly learning capacities and memory. In contrast, alpha 1-thymosin fragment decreased them. Other peptides only slightly affected the capacities. Two active peptides seem to affect the level of activation of subcortical structures responsible for the excitation and inhibition.
V F
VF
Martynov
L I
LI
Leont'eva
E I
EI
Sorochinskaia
D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography; D005260:Female; D006728:Hormones / Q000494:pharmacology*; D007858:Learning / Q000187:drug effects* / Q000502:physiology; D008297:Male; D008568:Memory / Q000187:drug effects* / Q000502:physiology; D010446:Peptide Fragments / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D012919:Social Behavior; D013951:Thymus Hormones / Q000494:pharmacology*
D006728:Hormones; D010446:Peptide Fragments; D013951:Thymus Hormones
Vliianie sinteticheskikh fragmentov peptidnykh gormonov timusa na protessy obucheniia i pamiati.