[Role of 131I-metaiodobenzylguanidine scintigraphy in the diagnosis of intestinal carcinoids].
Iodine-131 metaiodobenzylguanidine (131I-MIBG) is concentrated in a variety of neuroendocrine tumors, such as pheochromocytoma and neuroblastoma. Other neuroendocrine tumors from the APUD-cell system such as carcinoid tumors, may possess this uptake capability as well. We investigated 11 patients suffering from intestinal carcinoid with 131I-MIBG in order to determine the value of MIBG scintigraphy in these tumors. MIBG scans were positive in 5 out of 11 patients (45%). False-positive MIBG-scans did not occur. No correlation between MIBG uptake, clinical symptoms and urinary 5-HIAA level could be found.
Abteilung für Klin. Nuklearmedizin, Univ.-Strahlenklinik, Heidelberg, BRD.
H
H
Bihl
M L
ML
Sautter-Bihl
K R
KR
Wilhelm
B
B
Kimmig
D019797:3-Iodobenzylguanidine; D000328:Adult; D000368:Aged; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging
D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine
Die Rolle der 131J-Metajodbenzylguanidin-(MIBG-) Szintigraphie in der Diagnostik der intestinalen Karzinoide.