Unusual suppression of Kell system antigens in a healthy blood donor.
Red cells of a Kp(a+) donor, ascertained as a result of screening donor red cell units with anti-Kpa, reacted only very weakly with anti-Kpb and demonstrated weakened expression of various other Kell and para-Kell antigens. Family studies revealed a Kp(a+) sister with similarly weakened expression of Kpb and other Kell and para-Kell antigens. Red cell morphology was normal in both of these individuals. This phenotype is different from any previously reported and is named the Allen phenotype.
Red Cross Blood Transfusion Service, Adelaide, South Australia.
P C
PC
Norman
G L
GL
Daniels
D001789:Blood Group Antigens / Q000276:immunology*; D005260:Female; D005838:Genotype; D006801:Humans; D007519:Isoantigens / Q000032:analysis / Q000235:genetics; D007626:Kell Blood-Group System / Q000235:genetics / Q000276:immunology*; D008297:Male; D010375:Pedigree; D010641:Phenotype
D001789:Blood Group Antigens; D007519:Isoantigens; D007626:Kell Blood-Group System