[Early diagnosis of sepsis in the preterm neonate].
The usefulness of the neutrophil blood cell count, the ratio of band forms to total neutrophils, the platelet count, the quantitative determination of serum IgM, C-reactive protein, alpha-1-acid glycoprotein and haptoglobin for the early identification of the serious neonatal infections was evaluated in 70 preterm newborns: 15 with sepsis, 2 with serious infections, 53 without infections. None of these tests has proved sensitive and predictive enough to be used as a single measure. The combination of 2 or more of them had improve the sensitivity (76.4%) and the predictive value of negative test (91.6%). The authors suggest that the greatest potential value of the tests is to exclude infections, with a more than 90% probability, if they are negative.
Istituto di Clinica Pediatrica, Università Cattolica del Sacro Cuore, Roma, Italia.
A
A
Stabile
M
M
Pastore
V
V
Romanelli
S S
SS
Miceli
G
G
Flamini
A
A
Pesaresi
D001424:Bacterial Infections / Q000175:diagnosis; D002097:C-Reactive Protein / Q000032:analysis; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis*; D007239:Infections / Q000175:diagnosis*; D007958:Leukocyte Count; D009504:Neutrophils; D009961:Orosomucoid / Q000097:blood; D010976:Platelet Count; D011446:Prospective Studies; D013997:Time Factors
D006242:Haptoglobins; D007075:Immunoglobulin M; D009961:Orosomucoid; D002097:C-Reactive Protein
Diagnosi precoce di sepsi nel neonato pretermine.