The human type II collagen gene (COL2A1) assigned to 12q14.3.
A cosmid clone containing the entire human type II alpha 1 collagen gene (COL2A1) was used as probe in the Southern analysis of DNA from a panel of human/hamster somatic cell hybrids containing different portions of human chromosome 12. Two of the hybrids exhibited a similar terminal deletion q14.3----qter, but one was positive for the gene while the other was negative. Therefore, the gene must reside in the region q14.3.
Law
M L
ML
Eleanor Roosevelt Institute for Cancer Research, Denver, CO.
Tung
L
L
Morse
H G
HG
Berger
R
R
Jones
C
C
Cheah
K S
KS
Solomon
E
E
D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D003094:Collagen / Q000235:genetics*; D006224:Cricetinae; D003582:Cytogenetics; D004247:DNA; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D009693:Nucleic Acid Hybridization
D003094:Collagen; D004247:DNA