Patent ductus arteriosus and retinopathy of prematurity in infants below 27 weeks gestation.
Retrospective study of infants who survived the neonatal period after delivery at 24-26 weeks gestation revealed patency of the ductus arteriosus (PDA) in 44%. The mean birthweight of infants who developed PDA was lower. Retinopathy of prematurity (ROP) was seen in 79% of survivors with 24% having grade III or IV involvement. All but one of the more severe grades of ROP occurred among infants with PDA. Infants with PDA required more prolonged ventilatory support. Perinatal factors did not have a significant role in the development of these complications.
Department of Paediatrics, Westmead Hospital, New South Wales, Australia.
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John
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Todd
D001724:Birth Weight; D004374:Ductus Arteriosus, Patent / Q000150:complications*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000150:complications*; D008297:Male; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012121:Respiration, Artificial; D012178:Retinopathy of Prematurity / Q000150:complications* / Q000209:etiology; D012189:Retrospective Studies