[Alpha-rhythm asymmetry of schizophrenic patients before and after tryptophan administration].
Before and one hour after tryptophan loading laterality differences in the alpha-waves were evaluated from the EEG data obtained from 16 right-handed patients with paranoid hallucinatory schizophrenia and 16 right-handed controls. The alpha wave asymmetry of the patients which was increased and shifted to the right before tryptophan loading may be due to a disturbed relationship between both hemispheres. Particularly in the patients, the pronounced changes in the laterality of alpha-waves after tryptophan loading demonstrate that like psychotic substances tryptophan and its metabolites may bring about changes in subcortical and cortical asymmetries.
Klinik für Neurologie und Psychiatrie des Bereiches Medizin (Charité), Humboldt-Universität zu Berlin.
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Gorynia
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Uebelhack
D000208:Acute Disease; D000328:Adult; D000513:Alpha Rhythm; D004292:Dominance, Cerebral / Q000187:drug effects*; D005260:Female; D006212:Hallucinations / Q000523:psychology; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000503:physiopathology*; D012563:Schizophrenia, Paranoid / Q000523:psychology; D012565:Schizophrenic Psychology; D014364:Tryptophan
D014364:Tryptophan
Die Alphawellenasymmetrie von schizophrenen Patienten vor und nach einer Tryptophanbelastung.