Reinfection of bovine mammary glands following dry-cow antibiotic therapy.
Dry-cow antibiotic therapy (DCT) was administered to quarters with Staphylococcus aureus or streptococcal infections and the quarters were closely monitored for the presence of new or reactivated mammary infections throughout the dry period and the following lactation. Strains of S. aureus were characterized using a selection of biotyping tests to allow a comparison of S. aureus strains isolated before and after DCT. Cows with 3-4 quarters infected prior to DCT had a high susceptibility to reinfection in the following year. In contrast, for cows with 1-2 quarters infected prior to DCT and for heifers with no previous history of infection, the susceptibility to reinfection or new infection was very low. The majority of the S. aureus infections appearing in the lactation following DCT were due to S. aureus strains which differed from strains isolated prior to DCT, suggesting that these were new infections. Histopathological examination of quarters which had had recurrent S. aureus infections revealed lesions typical of chronic S. aureus mastitis, including extensive lobular fibrosis and atrophy.
Wallaceville Animal Research Centre, Ministry of Agriculture and Fisheries, Upper Hutt, New Zealand.
B M
BM
Buddle
M
M
Herceg
M J
MJ
Ralston
H D
HD
Pulford
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology / Q000517:prevention & control; D003023:Cloxacillin / Q000627:therapeutic use*; D005260:Female; D008414:Mastitis, Bovine / Q000382:microbiology / Q000517:prevention & control*; D008892:Milk / Q000382:microbiology; D012008:Recurrence; D013203:Staphylococcal Infections / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D013211:Staphylococcus aureus / Q000145:classification; D013290:Streptococcal Infections / Q000517:prevention & control / Q000662:veterinary*
D003023:Cloxacillin