Inhibition of the formation of protein storage granules by glutaurine in the larval fat body cells of Mamestra brassicae (Insecta, Lepidoptera).
Correlative changes in the protein contents of haemolymph and fat body and the accumulation of protein storage granules in the fat body cells of Mamestra brassicae were investigated during the last larval stage in normally developing larvae and following administration of glutaurine (1 X 10(-4) mg/g body weight). The protein content of the haemolymph of untreated larvae increased up to the 4th day of the stage, declined during days 5 and 6, and increased again before pupation. In the glutaurine-treated larvae the amount of proteins in the haemolymph was as high as in the controls during the first four days but continued to rise up to the end of the stage. The protein content of the fat body started to increase from the 3rd day and heavy accumulation of protein storage granules in the cells of fat body was observed on the 5th and following days. The protein content of the fat body of glutaurine-treated larvae remained at a low level and the protein storage granules were absent in the cells. The inhibition of the selective uptake of haemolymphatic storage proteins by fat body following glutaurine treatment is suggested.
Dept. Gen. Zool., Eötvös Univ., Budapest, Hungary.
M
M
Sass
L G
LG
Kömüves
J
J
Kovács
L
L
Feuer
D000273:Adipose Tissue / Q000187:drug effects*; D000818:Animals; D003594:Cytoplasmic Granules / Q000187:drug effects* / Q000648:ultrastructure; D005216:Fat Body / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D005973:Glutamine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006458:Hemolymph / Q000032:analysis; D007814:Larva / Q000187:drug effects; D007915:Lepidoptera / Q000187:drug effects*; D008675:Metamorphosis, Biological / Q000187:drug effects; D008854:Microscopy, Electron; D009036:Moths / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D011506:Proteins / Q000032:analysis*; D013654:Taurine / Q000031:analogs & derivatives* / Q000494:pharmacology
D011506:Proteins; D005973:Glutamine; D013654:Taurine; C020903:glutaurine