Holoprosencephaly in Border Leicester lambs.
Holoprosencephaly in Border Leicester lambs is described. This defect is characterised by lack of the longitudinal cerebral fissure, fusion of the cerebral hemispheres and a single lateral ventricle. Facial defects are also associated with this condition. Results of a breeding experiment suggest that it is inherited in an autosomal recessive manner. Results from a survey indicate that the condition is widespread in Border Leicester sheep.
Roth
I J
IJ
New South Wales Department of Agriculture, Tamworth.
Morrow
C J
CJ
Wilkins
J F
JF
Harper
P A
PA
D000015:Abnormalities, Multiple / Q000662:veterinary*; D000818:Animals; D001921:Brain / Q000002:abnormalities*; D005147:Facial Bones / Q000002:abnormalities*; D012756:Sheep; D012757:Sheep Diseases / Q000151:congenital* / Q000473:pathology; D012886:Skull / Q000002:abnormalities*