Failure of articular process (zygaphophyseal) joint development as a cause of vertebral fusion (blocked vertebrae).
Examination of congenitally fused (blocked) vertebrae in this study suggests that non-development of the joint between articular facets results in fusion of the vertebral arches which in turn leads to secondary fusion of the bodies and hypoplasia of the intervertebral discs. The presence of independent pedicles and transverse processes do not favour the concept that such an abnormality is the result of non-segmentation of the sclerotome. The condition is probably linked to a defect of an inductor substance which influences normal morphogenesis of the vertebral arch in the embryonic period.
Department of Anatomy, Phillip Institute of Technology, Bundoora, Victoria, Australia.
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Chandraraj
D002574:Cervical Vertebrae / Q000002:abnormalities* / Q000473:pathology; D006801:Humans; D007596:Joints / Q000002:abnormalities*; D013904:Thoracic Vertebrae / Q000002:abnormalities* / Q000473:pathology