[Effect of hydrocortisone on postradiation disorders of potassium homeostasis in the hepatocytes of irradiated rats].
The influence of hydrocortisone and radiation on potassium homeostasis in isolated hepatocytes (in vivo experiments) and perfusing liver of mongrel rats has been investigated. The effects of hydrocortisone and radiation (7 Gy) on redistribution of intracellular potassium are shown to be similar with respect to their depth and direction. However with the hormone and ionizing radiation delivered simultaneously no additivity of the effects is registered.
N Iu
NIu
Mashkova
G V
GV
Borovikova
G A
GA
Dokshina
D000818:Animals; D004305:Dose-Response Relationship, Drug; D006706:Homeostasis / Q000187:drug effects* / Q000528:radiation effects; D006854:Hydrocortisone / Q000494:pharmacology*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D010477:Perfusion / Q000379:methods; D011188:Potassium / Q000528:radiation effects*; D051381:Rats; D013997:Time Factors
D011188:Potassium; D006854:Hydrocortisone
Vliianie gidrokortizona na postradiatsionnye narusheniia gomeostaza kaliia v gepatotsitakh obluchennykh krys.