[A cylindrical thermistor probe for experiments on suppositories in rabbits].
A cylindrical thermistor probe with a rubber disk stopper, which is beneficial for inserting a suppository into the rectum of rabbits without removal of the probe from the rectum, was developed. It is possible to measure body temperature continuously by using this probe in an experiment to assess the effects of a suppository on the body temperature of rabbits. After insertion of a suppository, leakage of the melted suppository from the rectum was not observed. No differences between this thermistor probe and an ordinary thermistor probe in the ability of the probe to detect the febrile response of rabbits injected with a bacterial pyrogen were observed. From these results, it could be concluded that this newly improved cylindrical thermistor probe is suitable for studying the effect of suppositories on the body temperature of rabbits.
Sakamoto
J
J
National Institute of Hygienic Sciences, Osaka Branch, Japan.
Itami
T
T
Ema
M
M
Kawasaki
H
H
D000818:Animals; D001831:Body Temperature; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods; D011817:Rabbits / Q000502:physiology*; D013488:Suppositories
D013488:Suppositories