Lupus retinopathy. Patterns, associations, and prognosis.
In a prospective study of 550 patients with systemic lupus erythematosus (SLE), 41 were found to have retinopathy. Lupus retinopathy in the majority of cases consisted of a microangiopathy, with an excellent prognosis for vision. Five patients developed other complications that resulted in loss of visual acuity. Lupus retinopathy was associated with active SLE in 88% of patients and with lupus cerebritis in 73% of cases. Retinopathy in SLE was a marker of poor prognosis for survival.
University of Toronto, Rheumatic Disease Unit, Wellesley Hospital, Ontario, Canada.
F J
FJ
Stafford-Brady
M B
MB
Urowitz
D D
DD
Gladman
M
M
Easterbrook
D000328:Adult; D005128:Eye Diseases / Q000150:complications; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000401:mortality / Q000503:physiopathology; D008297:Male; D009422:Nervous System Diseases / Q000150:complications; D011379:Prognosis; D012164:Retinal Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D012171:Retinal Vessels / Q000473:pathology; D013997:Time Factors; D014792:Visual Acuity