Effects of endolymphatic sac obliteration on the cochlear duct glycocalyx.
The ultrastructural effects of surgical obliteration of the endolymphatic duct and sac on the cochlear duct glycocalyx were investigated using osmium tetroxide-potassium rutheniumcyanide postfixation. After 2 and 3 months a less prominent glycocalyx contrast staining was observed, together with disappearance of interconnecting material between the stereocilia of the inner and outer hair cells. Possible factors involved in this phenomenon are discussed.
Department of Otorhinolaryngology, University Hospital Utrecht, The Netherlands.
F W
FW
Albers
J C
JC
de Groot
J E
JE
Veldman
E H
EH
Huizing
D000818:Animals; D003051:Cochlea / Q000648:ultrastructure*; D003053:Cochlear Duct / Q000032:analysis / Q000648:ultrastructure*; D007758:Ear, Inner / Q000502:physiology*; D004712:Endolymphatic Sac / Q000502:physiology*; D006023:Glycoproteins / Q000032:analysis*; D006168:Guinea Pigs; D006199:Hair Cells, Auditory, Inner / Q000032:analysis / Q000648:ultrastructure; D008854:Microscopy, Electron; D011134:Polysaccharides / Q000032:analysis*
D006023:Glycoproteins; D011134:Polysaccharides