Biopharmaceutical studies of thiazide diuretics. III. In vivo formation of 2-amino-4-chloro-m-benzenedisulfonamide as a metabolite of hydrochlorothiazide in a patient.
Okuda
T
T
Itoh
S
S
Yamazaki
M
M
Nakahama
H
H
Fukuhara
Y
Y
Orita
Y
Y
D001702:Biopharmaceutics; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000378:metabolism*; D008875:Middle Aged; D013424:Sulfanilamides / Q000378:metabolism*
D013424:Sulfanilamides; D006852:Hydrochlorothiazide; C054586:4-amino-6-chloro-1,3-benzenedisulfonamide