Ureterocolonic anastomosis in clinically normal dogs.
Ureterocolonic anastomosis was evaluated in 13 clinically normal dogs. Urinary continence was maintained after surgery, and the procedure was completed without technique errors in all but 2 dogs. Three dogs died within 5 weeks (2 of undetermined causes and 1 of aspiration pneumonia and neurologic disease), and 1 dog was euthanatized 4 months after surgery because of neurologic signs. Two healthy dogs were euthanatized 3 months after surgery for light microscopic evaluation of their kidneys. Five dogs were euthanatized 6 months after surgery for light microscopic evaluation of their kidneys. Gastrointestinal and neurologic disturbances developed in 4 dogs at various postoperative intervals. Plasma ammonia concentration measured in 2 dogs with neurologic signs was increased. Plasma ammonia concentration measured in 5 dogs without neurologic signs was within normal limits. All 5 dogs, in which metabolic acidosis was diagnosed, had high normal or above normal serum chloride concentration. Serum urea nitrogen values were increased after surgery because of colonic absorption of urea. Serum creatinine concentration was increased in 1 dog 6 months after surgery. Individual kidney glomerular filtration rate was reduced in 38% (3/8) of the kidneys from 4 other dogs at 6 months after surgery. Of 5 dogs euthanatized at 3 to 4 months after surgery, 4 had bilateral pyelitis, and 1 had unilateral pyelonephritis. Six months after surgery, pyelonephritis was diagnosed in 40% (4/10) of the kidneys from 5 dogs. The ureterocolonic anastomosis procedure is a salvage procedure that should allow complete cystectomy. However, variable degrees of metabolic acidosis, hyperammonemia, and neurologic disease may result.
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104.
E A
EA
Stone
M C
MC
Walter
M H
MH
Goldschmidt
D N
DN
Biery
K C
KC
Bovée
D000714:Anastomosis, Surgical / Q000662:veterinary*; D000818:Animals; D003106:Colon / Q000601:surgery*; D004283:Dog Diseases / Q000209:etiology; D004285:Dogs / Q000601:surgery*; D005243:Feces; D005260:Female; D008297:Male; D011183:Postoperative Complications / Q000662:veterinary; D014513:Ureter / Q000601:surgery*; D014547:Urinary Diversion / Q000662:veterinary*