[Recurrent staphylodermas in marked IgE elevation: the hyper-IgE syndrome].
This is a report of a 6-year-old boy with repeated staphylococcus infections especially in the hairy region of the head. Investigating the disease an extremely elevated IgE of 10,000 KU/l was found, specific IgE in RAST only at a low level. The immunologic investigations showed a reduction of the T-suppressor-cells and an increase of IgG levels. Defects of phagocytosis or chemotaxis could not be demonstrated.
Universitäts-Kinderklinik, St. Josef Hospital Bochum.
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Huber
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Mietens
D002648:Child; D006801:Humans; D006942:Hypergammaglobulinemia / Q000276:immunology*; D007108:Immune Tolerance; D007073:Immunoglobulin E / Q000378:metabolism*; D008297:Male; D011711:Pyoderma / Q000276:immunology*; D012008:Recurrence; D012536:Scalp Dermatoses / Q000276:immunology*; D013203:Staphylococcal Infections / Q000276:immunology*; D013577:Syndrome
D007073:Immunoglobulin E
Rezidivierende Staphylodermien bei ausgeprägter IgE-Erhöhung: Hyper-IgE-Syndrom.