[UltrastructuraL analysis of the action of levorin on Entamoeba].
The paper is concerned with investigation of the nature of ultrastructural alterations in Entamoeba moshkovski under the levorin effect. The studies showed that under the effect of levorin there appeared in the Entamoeba cultures diverse types of cells having chiefly the following ultrastructural alterations: a higher number and size of cytoplasmic vacuoles, lower density of the cytoplasm granular component, not intact nuclear and plasmatic membranes and cell cytolysis. Analysis of the experimental results suggested that the amebicidal effect of levorin on Entamoeba was mainly associated with its membranotropic properties.
Ovnanian
K O
KO
Liubimova
L K
LK
Ivanova
L N
LN
Sukhareva-Nemakova
N N
NN
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D002174:Candicidin / Q000494:pharmacology*; D002462:Cell Membrane / Q000187:drug effects / Q000648:ultrastructure; D003593:Cytoplasm / Q000187:drug effects / Q000648:ultrastructure; D004305:Dose-Response Relationship, Drug; D004747:Entamoeba / Q000187:drug effects* / Q000648:ultrastructure; D008854:Microscopy, Electron / Q000379:methods; D013997:Time Factors
D000935:Antifungal Agents; D002174:Candicidin
Ul'trastrukturnyĭ analiz deĭstviia levorina na éntameb.