Identification of an anthraquinone pigment and a hydroxystilbene antibiotic from Xenorhabdus luminescens.
The entomopathogenic bacterium Xenorhabdus luminescens produces a red pigment and an antibiotic in insect carcasses in which it grows and in axenic cultures. The pigment was purified and identified as the anthraquinone derivative 1,6-dihydroxy-4-methoxy-9,10-anthraquinone, which exhibits a pH-sensitive color change, i.e., it is yellow below pH 9 and red above pH 9. The antibiotic was also purified and identified as the hydroxystilbene derivative 3,5-dihydroxy-4-isopropylstilbene.
Department of Chemistry, San Diego State University, California 92812.
W H
WH
Richardson
T M
TM
Schmidt
K H
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Nealson
D000818:Animals; D000880:Anthraquinones / Q000096:biosynthesis*; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000302:isolation & purification; D001419:Bacteria / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D007313:Insecta; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010860:Pigments, Biological / Q000096:biosynthesis* / Q000302:isolation & purification; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D010860:Pigments, Biological