Choline acetyltransferase-immunoreactive neurons in fetal monkey cerebral cortex.
Two monoclonal antibodies to choline acetyltransferase (ChAT) were used to stain the cerebral cortex of fetal monkeys at 110-150 days post-conception. In addition to a small number of immunostained fibers, cells resembling typical non-pyramidal neurons were immunostained in developing layers V and VI and in the subjacent white matter of each area examined (sensory-motor and visual areas). ChAT-immunoreactive neurons have not been described in the cerebral cortex of adult primates, but the present observations indicate such neurons exist in the developing primate cortex.
Hendry
S H
SH
Department of Anatomy and Neurobiology, University of California, Irvine 92717.
Jones
E G
EG
Killackey
H P
HP
Chalupa
L M
LM
D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology* / Q000201:enzymology; D002795:Choline O-Acetyltransferase / Q000032:analysis*; D005333:Fetus / Q000166:cytology*; D008253:Macaca mulatta; D009474:Neurons / Q000201:enzymology*
D002795:Choline O-Acetyltransferase