Familial t(8;15)(p23.3;q22.3): report of two cases with dup(15) (q22.3----qter).
Two affected first cousins with duplication of 15(q22.3----qter) are reported. This resulted from a familial t(8;15)(p23.3;q22.3) translocation. The findings in these patients are compared with each other and with six other published cases. Anthropometric and dermatoglyphic findings are summarised.
Department of Medical Genetics, Indiana University School of Medicine, Indianapolis.
D J
DJ
Goldstein
R E
RE
Ward
W C
WC
Nichols
C G
CG
Palmer
D000015:Abnormalities, Multiple / Q000235:genetics; D000328:Adult; D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D002884:Chromosomes, Human, Pair 15; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D008297:Male; D008831:Microcephaly / Q000235:genetics*; D010375:Pedigree; D014178:Translocation, Genetic