Hemolytic uremic syndrome associated with cisplatin therapy.
An adolescent with a small round cell tumor of the chest wall, who was treated with cisplatin, developed hemolytic uremic syndrome with severe hypertension, which ultimately contributed to her death. Cisplatin's role as a possible causative agent of this syndrome is discussed. Recommendations are made for monitoring abnormalities that may signal the onset of this potential complication.
Department of Pediatrics, Cornell University Medical College, Manhasset, New York.
M E
ME
Weinblatt
E
E
Kahn
P G
PG
Scimeca
J A
JA
Kochen
D000293:Adolescent; D002945:Cisplatin / Q000009:adverse effects*; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D012509:Sarcoma / Q000188:drug therapy; D013899:Thoracic Neoplasms / Q000188:drug therapy
D002945:Cisplatin