[Effect of cholecystokinin and bombesin on the neuronal impulse activity of the ventromedial hypothalamic nucleus].
I.v. administration of the C-terminal sulfated cholecystokinin octapeptide as well as microapplication of its analogues to the eye sclera induced an increase of firing rate in over 1/3 neurons of the ventromedial nucleus. Administration of alitezin and analogues of bombesin induced inhibitory responses and infrequent burst activity in some of these neurons.
N V
NV
Lutsik
D000818:Animals; D001839:Bombesin / Q000031:analogs & derivatives / Q000494:pharmacology*; D002766:Cholecystokinin / Q000031:analogs & derivatives / Q000494:pharmacology*; D005071:Evoked Potentials / Q000187:drug effects; D008297:Male; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D011817:Rabbits; D014697:Ventromedial Hypothalamic Nucleus / Q000187:drug effects* / Q000502:physiology; D014851:Wakefulness / Q000187:drug effects
D002766:Cholecystokinin; D001839:Bombesin
Vliianie kholetsistokinina i bombezina na impul'snuiu aktivnost' neĭronov ventromedial'nogo iadra gipotalamusa.