[Complex formation of lithium hydroxybutyrate with ions of Na+, K+, Ba2+, Mg2+, and Ca2+].
The interaction of lithium hydrobutyrate (LiR) with ions of Na+, K+, Ba2+, Mg2+ and Ca2+ was studied. The coordination is implemented by atoms of oxygen of the carboxyl group. R forms the most stable complexes with ions of Mg2+ and Ca2+. Complexes of CaR+ and CaR2 types are formed with ions of Mg2+ and Ca2+. For LiR complex the logarithm of stability constant (lg K) is 0.7 +/- 0.3, for CaR+ - 2.0 +/- 0.2 and for CaR2 - 0.2 +/- 0.3. The interaction of lithium hydroxybutyrate with ions of Ca2+ and Mg2+ may be of great importance in the mechanism of its cardiotropic effect.
Galenko-Iaroshevckiĭ
P A
PA
Budarin
L I
LI
Buikliskiĭ
V D
VD
Grebennikov
V N
VN
Pokrovskiĭ
M V
MV
D004573:Electrolytes / Q000378:metabolism*; D006885:Hydroxybutyrates / Q000494:pharmacology*; D008094:Lithium / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D009942:Organometallic Compounds / Q000494:pharmacology*; D013816:Thermodynamics
D004573:Electrolytes; D006885:Hydroxybutyrates; D009942:Organometallic Compounds; C022826:lithium hydroxybutyrate; D008094:Lithium
Kompleksoobrazovanie litiia oksibutirata s ionami Na+, K+, Ba2+, Mg2+, and Ca2+.