Unusual suppression of Kell system antigens in a healthy blood donor.
Red cells of a Kp(a+) donor, ascertained as a result of screening donor red cell units with anti-Kpa, reacted only very weakly with anti-Kpb and demonstrated weakened expression of various other Kell and para-Kell antigens. Family studies revealed a Kp(a+) sister with similarly weakened expression of Kpb and other Kell and para-Kell antigens. Red cell morphology was normal in both of these individuals. This phenotype is different from any previously reported and is named the Allen phenotype.
Norman
P C
PC
Red Cross Blood Transfusion Service, Adelaide, South Australia.
Daniels
G L
GL
D001789:Blood Group Antigens / Q000276:immunology*; D005260:Female; D005838:Genotype; D006801:Humans; D007519:Isoantigens / Q000032:analysis / Q000235:genetics; D007626:Kell Blood-Group System / Q000235:genetics / Q000276:immunology*; D008297:Male; D010375:Pedigree; D010641:Phenotype
D001789:Blood Group Antigens; D007519:Isoantigens; D007626:Kell Blood-Group System