Antitumor agents, 90. Bruceantinoside C, a new cytotoxic quassinoid glycoside from Brucea antidysenterica.
Three cytotoxic, quassinoid glycosides, the new bruceantinoside C [1] and the known yadanziosides G [2] and N [3] were isolated from the stem of Brucea antidysenterica. The structures of 1-3 were determined from their spectral data.
Fukamiya
N
N
Faculty of Integrated Arts and Sciences, Hiroshima University, Japan.
Okano
M
M
Tagahara
K
K
Aratani
T
T
Muramoto
Y
Y
Lee
K H
KH
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D005900:Glaucarubin / Q000031:analogs & derivatives / Q000494:pharmacology*; D007939:Leukemia L1210 / Q000473:pathology; D007941:Leukemia P388 / Q000473:pathology; D009682:Magnetic Resonance Spectroscopy; D010616:Phenanthrenes / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000032:analysis*; D036702:Quassins; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000473:pathology
D000972:Antineoplastic Agents, Phytogenic; D010616:Phenanthrenes; D036702:Quassins; C055373:bruceantinoside C; D005900:Glaucarubin