[Sarcoidosis of the kidney].
Of 123 patients with sarcoidosis observed from 1971 to 1986, 4 had histologically proven renal involvement. Hypercalcemia was present in all of these 4 patients, hypercreatinemia in 3 and urolithiasis in one. Histologically renal interstitial nephritis or fibrosis was found in all 4 cases, and 3 cases showed sarcoid-like renale granulomas. In addition, nephrocalcinosis or mesangioproliferative glomerulonephritis was present in one patient each. Corticosteroid therapy corrected hypercalcemia in 3 patients and improved renal function in the patient with glomerulonephritis and in the case with interstitial fibrosis. One patient died of granulomatous myocarditis, renal insufficiency having been unaffected by corticosteroids.
Medizinische Klinik B, Kantonsspital St. Gallen.
C
C
Hug
F W
FW
Reutter
F
F
Gloor
D000328:Adult; D000368:Aged; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology / Q000473:pathology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D007674:Kidney Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009397:Nephrocalcinosis / Q000209:etiology / Q000473:pathology; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology
Sarkoidose der Niere.