RLSQ: T1, T2, and rho calculations, combining ratios and least squares.
A method is proposed for calculating images of spin density rho and relaxation times T1, T2 from MR imaging sequences with the following characteristics: it avoids nonlinear iterative techniques and is consequently sufficiently fast to allow calculation of rho, T1, and T2 on a pixel by pixel basis routinely; it uses all available data simultaneously in an approximately optimal fashion. The method is applied to the combined SE + IR sequence but can be used for other acquisition schemes as well.
In den Kleef
J J
JJ
Philips Medical Systems, Best, The Netherlands.
Cuppen
J J
JJ
D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008433:Mathematics