Autopsy findings in a Japanese patient with acquired immunodeficiency syndrome.
A 37-year-old Japanese man was diagnosed as having acquired immunodeficiency syndrome (AIDS) on the basis of a homosexual history, generalized lymphadenopathy, marked decrease of helper/inducer T cells in the peripheral blood, and positive serum antibody (antibodies) against human immunodeficiency virus (human T-lymphotropic virus type III/lymphadenopathy-associated virus). Autopsy showed severe depletion of lymphocytes in the lymphoid organs including the systemic lymph nodes, spleen, and gut-associated lymphoid tissue. Pneumocystis carinii pneumonia and adrenal cytomegalovirus infection ('necrotizing adrenalitis') were identified, but there was no neoplasm. Postmortem findings in AIDS were reviewed in the literature.
Nakamine
H
H
Department of Laboratory Medicine, Wakayama Medical School, Japan.
Shimizu
E
E
Nishino
E
E
Takenaka
T
T
Maeda
J
J
Hanaoka
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D000311:Adrenal Glands / Q000473:pathology; D000328:Adult; D001344:Autopsy; D006716:Homosexuality; D006801:Humans; D007564:Japan; D008168:Lung / Q000473:pathology; D008221:Lymphoid Tissue / Q000473:pathology; D008297:Male; D013154:Spleen / Q000382:microbiology