Altered ribosomal protein synthesis in congenital non-progressive myopathy.
Ribosomes isolated from fibroblasts, muscle tissues, and blood cells of a patient with congenital non-progressive myopathy were used for in vitro measurement of protein synthesis in a heterologous poly(U)-directed polyphenylalanine synthesis system. The activity of ribosomes obtained from the patient was 35% lower than that in normal controls.
Neurologische Klinik, Freie Universität Berlin.
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D000328:Adult; D001706:Biopsy; D006801:Humans; D008297:Male; D009132:Muscles / Q000473:pathology; D009136:Muscular Dystrophies / Q000151:congenital* / Q000473:pathology; D012269:Ribosomal Proteins / Q000096:biosynthesis*
D012269:Ribosomal Proteins