[Comparison of the effect of gamma-radiation and fast neutrons on the biosynthesis of DNA in rat bone marrow in different stages of proliferation].
In experiments with rats of different age exposed to gamma- or neutron-radiation it was shown that in younger animals, the inhibition of DNA synthesis in the bone marrow was of a lesser degree but more stable without a tendency toward recovery. Inhibition of DNA synthesis was more pronounced in mature rats, but in 18 h it was completely or partially eliminated. Neutrons of 1.5-2 MeV caused a more pronounced, than gamma-radiation, inhibition of DNA synthesis in all animals under study irrespective of their age: the inhibition was similar in animals with different levels of bone marrow proliferation.
Ushenkova
L N
LN
Mazurik
V K
VK
D000375:Aging / Q000378:metabolism*; D000818:Animals; D001853:Bone Marrow / Q000378:metabolism* / Q000528:radiation effects; D004247:DNA / Q000096:biosynthesis*; D005214:Fast Neutrons; D008297:Male; D009502:Neutrons; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats
D004247:DNA
Sravnenie vliianiia gamma-izlucheniia i bystrykh neĭtronov na biosintez DNK v kostnom mozge krys pri raznykh urovniakh proliferatsii.