[Changes in the levels of neurotensin and adenohypophyseal hormones in the acute period of craniocerebral injury].
Clinico-biochemical study in 51 patients in the acute period of craniocerebral trauma (CCT) and in 12 healthy individuals revealed impairment of the functional condition of the hypothalamus and hypophysis in the acute period of CCT. Evidence of this was the change in the blood neurotensin, prolactin, somatotropin, and thyrotropin levels. A dependence was found of the increase in the prolactin level on the severity of impaired consciousness (coma-sopor, stunning) on admission of the patient; changes in the prolactin and neurotensin contents were detected during the examination. Improvement of the condition of patients who were in a state of coma-sopor on admission was attended by an increase of the neurotensin level and reduction of the prolactin content in the blood. Correction of motor excitement was also attended by increase of the blood neurotensin content.
Tenedieva
V D
VD
Usvatova
I Ia
IIa
Potapov
A A
AA
Piasetskaia
M V
MV
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000097:blood* / Q000628:therapy; D002648:Child; D003128:Coma / Q000097:blood / Q000628:therapy; D003244:Consciousness Disorders / Q000097:blood / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009496:Neurotensin / Q000097:blood*; D010908:Pituitary Hormones, Anterior / Q000097:blood*; D011184:Postoperative Period
D010908:Pituitary Hormones, Anterior; D009496:Neurotensin
Izmenenie urovneĭ neĭrotenzina i gormonov adenogipofiza v ostrom periode cherepno-mozgovoĭ travmy.