Can 12-hour creatinine clearances be substituted for 24-hour creatinine clearances in monitoring for nephrotoxicity from cancer chemotherapy? A pilot study and preliminary data.
Preliminary analysis of 12-hour and 24-hour creatinine clearances on nine chemotherapy patients, suggests that the 12-hour creatinine clearance alone may be clinically acceptable for monitoring adverse nephrotoxic effects of chemotherapy.
Nichols
L
L
Department of Pathology, New England Deaconess Hospital, Massachusetts.
D000970:Antineoplastic Agents / Q000009:adverse effects*; D003404:Creatinine / Q000652:urine*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000652:urine; D008297:Male; D008657:Metabolic Clearance Rate; D013997:Time Factors
D000970:Antineoplastic Agents; D003404:Creatinine