Semiquantitative analysis of fatty liver using spectroscopic imaging by dephasing amplitude changing (SIDAC).
The potential utility of spectroscopic imaging by dephasing amplitude changing (SIDAC) was evaluated in fatty infiltration in rats induced by cholesterol and ethanol. There was an excellent correlation between the in vivo fat-to-water ratio obtained from SIDAC and that in liver specimens from in vitro measurement (r = 0.97). SIDAC is a promising method for semiquantitative analysis of fatty infiltration of the liver.
Ohtomo
K
K
Department of Radiology, University of Tokyo, Japan.
Yamada
S
S
Aoyama
H
H
Miyazaki
T
T
Iriguchi
N
N
Minami
M
M
Yoshikawa
K
K
Itai
Y
Y
Iio
M
M
Ogata
I
I
D000818:Animals; D001834:Body Water / Q000032:analysis; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D000431:Ethanol / Q000633:toxicity; D005234:Fatty Liver / Q000209:etiology / Q000378:metabolism* / Q000473:pathology; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000032:analysis* / Q000473:pathology; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D002791:Cholesterol, Dietary; D008055:Lipids; D000431:Ethanol