The role of GTP in the regulation of two forms of AMP deaminase from chicken kidney.
1. Two molecular forms of AMP deaminase have been revealed by phosphocellulose column chromatography of the chicken kidney extract. 2. The chromatographic, kinetic and regulatory properties of these two forms were similar to these of two enzyme forms previously found in the chicken liver, lizard liver and in rat small intestine. 3. GTP exerted different effect from MgGTP on the activity and kinetic parameters of both AMP deaminase I and II from chicken kidney.
Department of Biochemistry, Academic Medical School, Gdańsk, Poland.
J
J
Spychała
J
J
Marszałek
D000659:AMP Deaminase / Q000302:isolation & purification / Q000378:metabolism*; D000818:Animals; D002645:Chickens; D006160:Guanosine Triphosphate / Q000494:pharmacology*; D066298:In Vitro Techniques; D007668:Kidney / Q000201:enzymology*; D007700:Kinetics; D008297:Male; D009709:Nucleotide Deaminases / Q000378:metabolism*
C036852:magnesium GTP; D006160:Guanosine Triphosphate; D009709:Nucleotide Deaminases; D000659:AMP Deaminase