Sarcoidosis with hydrocephalus: report of a case successfully treated with a ventriculo-peritoneal shunt and methylprednisolone pulse therapy.
We describe a female patient with systemic sarcoidosis and hydrocephalus. She was initially satisfyingly treated with peroral steroids. When she later deteriorated, the treatment had to be changed due to side-effects. High dose intravenous methylprednisolone pulse therapy was tried with some, but insufficient, improvement. Therefore, a ventriculoperitoneal shunt operation was performed with immediate improvement. After that she was treated with intravenous methylprednisolone and her condition has remained proper and stable for 5 years. The possibility that pulse therapy might have contributed to the favourable course in our patient is discussed.
Department of Neurology, Sahlgren Hospital, Gothenburg, Sweden.
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T
Lundh
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Wikkelsö
D001927:Brain Diseases / Q000628:therapy*; D002557:Cerebrospinal Fluid Shunts; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D004833:Epilepsy, Temporal Lobe / Q000628:therapy; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000628:therapy*; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D012507:Sarcoidosis / Q000628:therapy*; D014057:Tomography, X-Ray Computed
D008775:Methylprednisolone