The value of immunoreactive lipase in acute pancreatitis.
We have evaluated a new agglutination test for serum immunoreactive lipase in 24 patients with abdominal pain and hyperamylasaemia. On admission all 20 patients with acute pancreatitis had a positive lipase test, 3 of the 4 patients who did not have pancreatitis had a negative lipase test. The sensitivity of the lipase test on day 1 is 100%, the specificity 96% and predictive value of a positive test is 95.2% compared to 83% for amylase. A negative test excludes pancreatitis. In addition, the test stays positive longer than hyperamylasaemia.
Department of Surgery and Biochemistry, Warrington District General Hospital.
D M
DM
Hemingway
I
I
Johnson
D J
DJ
Tuffnell
R S
RS
Croton
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004796:Clinical Enzyme Tests; D005260:Female; D006801:Humans; D007841:Latex Fixation Tests; D008049:Lipase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011933:Reagent Kits, Diagnostic
D011933:Reagent Kits, Diagnostic; D008049:Lipase