Severe liver damage caused by therapeutic doses of acetaminophen.
Two patients who ingested therapeutic doses of acetaminophen and who developed a severe hepatotoxicity are reported. Both patients had a rather high alcohol consumption, which probably made them susceptible to the toxic effects of acetaminophen.
Department of Internal Medicine, University Hospital, Lund, Sweden.
C H
CH
Florén
P
P
Thesleff
A
A
Nilsson
D000082:Acetaminophen / Q000008:administration & dosage / Q000009:adverse effects*; D000410:Alanine Transaminase / Q000097:blood; D000428:Alcohol Drinking; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000473:pathology; D008875:Middle Aged; D009336:Necrosis
D000082:Acetaminophen; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase