[Conventional and analytic morphometry using the IBAS-1 computer in experimental Trypanosoma b. brucei infection].
A comparative morphometrical study of the experimental infection with T. b. brucei was realized using the conventional method and the IBAS-1 analytic computer. The studied strain of T. b. brucei was preserved during 10 years in laboratory conditions, through inoculations from mice to mice. The effect of a low dose of suramin upon the percentage of different morphological forms of the parasite was analysed and compared with the untreated lots. Certain differences could be appreciated in the results of the two methods of morphometrical studies. The presence of posteronuclear, multinuclear and "stumpy" dividing forms was confirmed in our study. The administration of low doses of suramin produces a serious increase of the number of the dividing, multinuclear and "stumpy" forms.
Departamento de Medicina Social y Preventiva, Facultad de Medicina, Universidad Autónoma de Madrid, España.
J A
JA
de Diego
A
A
Higueras
C
C
Gamallo
R F
RF
Mayer
J
J
Rey Calero
D000818:Animals; D003201:Computers; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008853:Microscopy; D013498:Suramin / Q000494:pharmacology; D014346:Trypanosoma brucei brucei / Q000254:growth & development / Q000648:ultrastructure*; D014353:Trypanosomiasis, African / Q000469:parasitology*
D013498:Suramin
Morphométrie conventionnelle et analytique au moyen de l'ordinateur IBAS-1 dans l'infection expérimentale avec Trypanosoma b. brucei.