[Copper and zinc: release from the intact and reinnervated kidney and effect on membrane transport].
Within a few months after denervation of the dog kidney, during its reinnervation, an increased excretion of calcium and copper was observed, whereas the excretion of zinc, magnesium, sodium, potassium and chloride ions was the same as in the opposite intact kidney. Addition of copper or zinc ions to the outside frog skin was shown to increase the potential difference and the short circuit current whereas the inner side of the skin these elements inhibit both parameters. The data obtained suggest that renal nerves are involved in regulation of trace elements reabsorption and that copper and zinc from the tubular lumen may affect the luminal cell membrane and control the transport of substances from tubular fluid into the blood.
R A
RA
Gyrchev
Iu V
IuV
Natochin
D000818:Animals; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D003300:Copper / Q000378:metabolism*; D003714:Denervation; D004285:Dogs; D005260:Female; D007668:Kidney / Q000294:innervation* / Q000378:metabolism; D009416:Nerve Regeneration; D011898:Ranidae; D015032:Zinc / Q000378:metabolism*
D003300:Copper; D015032:Zinc
Med', tsink: vydelenie intaktnoĭ i reinnervirovannoĭ pochkoĭ, vliianie na membrannyĭ transport.