Late radiation effects in the mouse brain. A quantitative study on PAS positive deposits.
Mice received whole brain irradiation (250 kV roentgen rays) with single doses ranging from 13 to 25 Gy. PAS positive deposits, microscopically observed in the dorsal part of the ventral thalamic nucleus, were quantitatively scored at different intervals between 20 and 85 weeks after irradiation. A significant dose-dependent inhibition of the formation of these deposits was observed in the irradiated brains.
Department of Neurological Surgery, School of Medicine, University of Tsukuba, Ibaraki, Japan.
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Y
Yoshii
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Maki
D000818:Animals; D001921:Brain / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D006001:Glycoconjugates / Q000378:metabolism*; D051379:Mice; D010503:Periodic Acid-Schiff Reaction; D013997:Time Factors; D014965:X-Rays
D006001:Glycoconjugates