[Protective effect of total gaseous hypoxia on the development of remote pathology of the lungs in rats exposed to a one-time local irradiation].
A comparative study was conducted on the development of a remote radiation pathology in rat lungs after single local irradiation with doses of 10, 14.3 and 20 Gy in the air, and 14.3 and 20 Gy in a gas hypoxic mixture containing 10 per cent of oxygen. From the morphological evaluation of the dynamics and the degree of pneumosclerosis manifestations at different times following irradiation the protective effect of gas hypoxic mixture was evident whose value, as estimated by the accretion of the connective tissue in the exposed lung, was a function of radiation dose.
Dubrovskaia
V F
VF
Gubareva
A V
AV
D000818:Animals; D008168:Lung / Q000528:radiation effects*; D008297:Male; D010100:Oxygen / Q000502:physiology*; D011658:Pulmonary Fibrosis / Q000209:etiology / Q000517:prevention & control*; D051381:Rats; D013997:Time Factors
D010100:Oxygen
Zashchitnyĭ éffekt obshcheĭ gazovoĭ gipoksii na razvitie otdalennoĭ patologii legkikh krys, vyzvannoĭ odnokratnym lokal'nym oblucheniem.