[Postoperative radiation of retinoblastoma--report on 22 patients].
From July 1958 to December 1979, 22 patients with retinoblastoma were treated postoperatively by radiotherapy. All were proved by pathology. There were 12 stage I, 1 stage II, 8 stage III and 1 stage IV lesions. Radiation dose was more than 15 Gy and most of the patients received 40-50 Gy in 4-5 weeks. The overall cancer free 5 year survival rate was 55% (12/22). The 5 year survival rate of stage I patients was 75% (9/12), and that of stage III patients was 38% (3/8). None of the stage II and IV patients survived. Dose of 40-50 Gy/4-5 wk is considered to be optimal for control of the tumor. Dose higher than 60 Gy/6 wk could lead to retarded growth in the orbital and temporal bony structures if the patient survives for ten years or more.
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
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D002648:Child; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011182:Postoperative Care; D012175:Retinoblastoma / Q000532:radiotherapy* / Q000601:surgery