title: [Polygraphic therapy control in Gilles de la Tourette syndrome--a case report].
abstract: In a female patient with Gilles-de-la Tourette syndrome (GTS) the clinical improvement during drug therapy of haloperidol and clomipramine was proved with the help of a polygraphic method (simultaneous recording of different electrophysiological and vegetative parameters). Before intensifying therapy symptoms of vegetative irritation, motoric discharge patterns with high amplitude in correlation with movements and permanent activity with low amplitude even in a state of external motoric rest were found. After intensifying therapy vegetative stabilization and ceasing of any electrical activity in the EMG could be demonstrated. It is concluded that the effects of therapy in GTS may be checked and quantified by means of polygraphic methods.
authors.forename: M
authors.initials: M
authors.lastname: Seidel
authors.forename: I
authors.initials: I
authors.lastname: Gorynia
mesh_terms: D000328:Adult; D001143:Arousal / Q000187:drug effects; D002540:Cerebral Cortex / Q000187:drug effects*; D002997:Clomipramine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004576:Electromyography; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use*; D006801:Humans; D005879:Tourette Syndrome / Q000188:drug therapy*
chemical_list: D006220:Haloperidol; D002997:Clomipramine
vernacular_title: Polygraphische Therapie-Kontrolle bei Gilles-de-la-Tourette-Syndrom--Eine Fallstudie.