Reduction of blood pressure in salt-fed Dahl salt-sensitive rats with diets rich in olive oil, safflower oil or calcium biphosphate but not with calcium carbonate.
Increased dietary calcium as CaCO3 had no effect in NaCl-induced hypertension in Dahl salt-sensitive (Dahl-S) rats, while the calcium supplementation as CaHPO4 did lower the blood pressure (BP). A diet rich in either monounsaturated or polyunsaturated fatty acids produced a significant lowering of blood pressure compared with the relatively saturated palm-oil diet in NaCl-induced hypertension in Dahl-S rats. The lower BP found with olive oil is probably not related to increased amounts of PGE2 and PGI2.
Ganguli
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MC
Tobian
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Iwai
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D000818:Animals; D002119:Calcium Carbonate / Q000008:administration & dosage; D002131:Calcium Pyrophosphate / Q000008:administration & dosage; D002136:Calcium, Dietary / Q000008:administration & dosage*; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage*; D004351:Drug Resistance / Q000235:genetics; D006973:Hypertension / Q000178:diet therapy* / Q000235:genetics; D000069463:Olive Oil; D010938:Plant Oils / Q000008:administration & dosage; D051381:Rats; D012450:Safflower Oil / Q000008:administration & dosage; D012965:Sodium Chloride / Q000008:administration & dosage*
D002136:Calcium, Dietary; D004042:Dietary Fats, Unsaturated; D000069463:Olive Oil; D010938:Plant Oils; D012965:Sodium Chloride; D012450:Safflower Oil; D002119:Calcium Carbonate; D002131:Calcium Pyrophosphate