[Synthesis and properties of an affinity sorbent for extraction of atherogenic lipoproteins].
A digitonin-containing affinity sorbent was prepared using a hydrophilic polymer carrier. The correlation was found between the polymer structure and crosslink. King degree, on the one hand, and the sorbent capacity to bind cholesterol, protein and lipoproteins--on the other. The sorbent was demonstrated to extract predominantly atherogenic lipoproteins from blood plasma.
Andrianova
I P
IP
Rabovskiĭ
A B
AB
Zuevskiĭ
V V
VV
Tsybul'skaia
M V
MV
Samoĭlova
N A
NA
D000818:Animals; D001053:Apolipoproteins / Q000097:blood / Q000302:isolation & purification; D001161:Arteriosclerosis / Q000097:blood*; D002784:Cholesterol / Q000097:blood / Q000302:isolation & purification*; D008078:Cholesterol, LDL / Q000097:blood / Q000302:isolation & purification*; D015243:Cholesterol, VLDL; D004072:Digitonin; D006464:Hemoperfusion; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood / Q000302:isolation & purification*; D008299:Maleic Anhydrides; D011108:Polymers / Q000032:analysis / Q000138:chemical synthesis; D011760:Pyrrolidinones; D011817:Rabbits
D001053:Apolipoproteins; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D008079:Lipoproteins, VLDL; D008299:Maleic Anhydrides; D011108:Polymers; D011760:Pyrrolidinones; C042670:N-vinyl-2-pyrrolidinone; D002784:Cholesterol; D004072:Digitonin
Sintez i svoĭstva affinnogo sorbenta dlia izvlecheniia aterogennykh lipoproteinov.