Albumin to creatinine ratio: an unreliable index of 24 h albumin excretion in healthy adults.
The urine albumin to creatinine ratio was studied on four timed collections during a 24 h period in a group of 30 healthy volunteers. The results show large within and between subject variation not explained by exercise, and the absence of a predictable diurnal pattern. It was not possible to predict the 24 h excretion of albumin from the albumin to creatinine ratio of a separately collected random urine sample. The large variations of the ratio observed in healthy subjects stress the need for 24 h urine collections rather than random samples when assessing albumin excretion.
Townsend
J C
JC
D000328:Adult; D000419:Albuminuria / Q000652:urine*; D002940:Circadian Rhythm; D003404:Creatinine / Q000652:urine*; D006801:Humans; D008297:Male
D003404:Creatinine