title: Pharmacokinetics of metamizol metabolites.
abstract: When administered to humans, metamizol rapidly undergoes predominantly nonenzymatic biotransformation, yielding a vast number of active and later inactive metabolites. The biotransformational pathways and the clinical significance of the metabolites are discussed in the light of their individual pharmacokinetics.
authors.forename: M
authors.initials: M
authors.lastname: Levy
mesh_terms: D000107:Acetylation; D000632:Aminopyrine / Q000031:analogs & derivatives*; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D004177:Dipyrone / Q000031:analogs & derivatives / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008657:Metabolic Clearance Rate; D011485:Protein Binding
chemical_list: D000632:Aminopyrine; D004177:Dipyrone