Influence of taurine on the posthypoxic dopamine release inhibition in comparison to piracetam.
Taurine (10 mg/kg) does not show any effects on the posthypoxic inhibition of dopamine release from rat striatum slices. When given twice a day for a fortnight, the drug exhibits almost a total protection of release mechanisms. On that account, piracetam acts restitutively.
Fischer
H D
HD
Institute of Pharmacology and Toxicology, Medical Academy Carl Gustav Carus, Dresden, GDR.
Wustmann
C
C
Schmidt
J
J
D000818:Animals; D003342:Corpus Striatum / Q000187:drug effects / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism*; D002534:Hypoxia, Brain / Q000188:drug therapy* / Q000503:physiopathology; D066298:In Vitro Techniques; D010889:Piracetam / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013654:Taurine / Q000494:pharmacology*
D013654:Taurine; D004298:Dopamine; D010889:Piracetam