Homogeneity of HLA-DQ,DR phenotypes in lymphocyte subsets of normal individuals.
The study was performed to evaluate the association of HLA-DQ and DR antigens with the composition of peripheral blood lymphocytes. B cells, T cells, and T subsets were enumerated in 200 normal individuals by indirect immunofluorescence microscopy using the monoclonal antibodies OKT3, OKT4, OKT8, and OKIa1. Results were related to the HLA-DQ,DR phenotypes of the investigated population. No significant correlation between any of the lymphocyte subsets and of the HLA-DQ,DR antigens was found.
Bertrams
J
J
Luboldt
W
W
Dannehl
K
K
Baur
M P
MP
D000911:Antibodies, Monoclonal / Q000276:immunology; D005260:Female; D005787:Gene Frequency; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis* / Q000235:genetics; D006801:Humans; D008214:Lymphocytes / Q000145:classification* / Q000276:immunology; D008285:Major Histocompatibility Complex; D008297:Male; D010641:Phenotype
D000911:Antibodies, Monoclonal; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II