title: The long-term effect of distal lienorenal shunt surgery on portal venous pressure.
abstract: To assess whether portal venous pressure remains elevated following distal lienorenal shunt surgery, 11 patients with alcoholic cirrhosis were assessed from 0.5 to 59 months following the creation of a distal lienorenal shunt. These were compared with five patients following mesocaval shunt surgery and nine with cirrhosis alone. Portal pressure was measured by direct transhepatic catheterization of the portal vein or by determining intrahepatic pulp pressure. Splenic pulp pressure was also measured in the shunt groups at the time of assessment of shunt patency by scintisplenoportography. All shunts were patent. Four of five patients studied within 10 months of distal lienorenal shunt surgery had persisting portal hypertension (comparable with that in the cirrhosis alone group) and persisting portasplenic gradient. In contrast, five of six patients studied more than 10 months following surgery had portal pressures similar to that following mesocaval shunt surgery and no portasplenic gradient. Thus, with time, selective decompression tends to become total decompression. Whether this correlates with deterioration of hepatic function requires further study.
authors.forename: P R
authors.initials: PR
authors.lastname: Gibson
authors.forename: I E
authors.initials: IE
authors.lastname: McInnes
authors.forename: F J
authors.initials: FJ
authors.lastname: Dudley
mesh_terms: D006801:Humans; D006975:Hypertension, Portal / Q000601:surgery*; D008102:Liver Circulation; D008103:Liver Cirrhosis / Q000601:surgery*; D011170:Portasystemic Shunt, Surgical; D011184:Postoperative Period