Combined irradiation and low-dose cyclophosphamide in the treatment of Graves' ophthalmopathy.
The treatment of a patient with euthyroid Graves' ophthalmopathy is described. A poor response was obtained from large doses of prednisone whereas a combination of orbital irradiation and low dose cyclophosphamide induced a dramatic resolution. As there is no fully satisfactory treatment for this condition, this combined therapy deserves further investigation.
Teoh
R
R
Department of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin.
Woo
J
J
D000328:Adult; D001327:Autoimmune Diseases / Q000628:therapy*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006111:Graves Disease / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans
D003520:Cyclophosphamide