[Structure of the bone marrow stroma and hematopoiesis following chemotherapy in patients with acute myeloblastic leukemia].
Histometric methods were used to examine interrelations between hemopoiesis and bone marrow stroma in the trepanned iliac bones from 17 healthy subjects, 30 patients with acute myeloblastic leukemia and 6 patients at different times after chemotherapy. In health, young granulocytes were located endosteally, less frequently along the periphery of the vessels and around reticular cells. Erythro-normoblasts were mostly demonstrable perivascularly or near reticular cells and macrophages. During acute myeloblastic leukemia the interrelations under consideration were deranged. The significance of the endosteum in the regeneration of the stroma and hemopoiesis after cytostatic aplasia is demonstrated.
Rugal'
V I
VI
Abdulkadyrov
K M
KM
Patterson
D
D
Zubarovskaia
L S
LS
Afanas'ev
B V
BV
D000273:Adipose Tissue / Q000187:drug effects / Q000473:pathology; D001706:Biopsy; D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology*; D003238:Connective Tissue / Q000187:drug effects / Q000473:pathology; D006410:Hematopoiesis / Q000187:drug effects; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000473:pathology*
Struktura stromy kostnogo mozga i gemopoéz posle khimioterapii bol'nykh ostrym mieloblastnym leĭkozom.