Effect of a sport drink mixture with and without addition of fluoride and magnesium on plaque formation, dental caries and general health of rats.
A sport drink mixture (pH 3.2) containing 6% sucrose was given to Osborne-Mendel rats for 42 days. In some experimental groups the drink was supplemented with 15 ppm F, 38.5 ppm Mg or both F and Mg. The rats were fed a slightly cariogenic powdered diet containing 15% sucrose. Sport drink mixture increased significantly the accumulation of plaque but, compared with a group that drank distilled water, did not affect caries. Addition of fluoride to the sport drink mixture, alone or with magnesium, significantly reduced caries and tended to decrease plaque; addition of magnesium had no clear effect on plaque or caries. In spite of the fact that the rats had a sport drink mixture as the only drink for 6 wk, there were no untoward effects on growth, in histological studies of the inner organs, or in Ca, Mg, Na and K contents of kidney, heart and aorta.
Sorvari
R
R
Koskinen-Kainulainen
M
M
Sorvari
T
T
Luoma
H
H
D000818:Animals; D001011:Aorta / Q000378:metabolism; D001628:Beverages; D001835:Body Weight / Q000187:drug effects; D003731:Dental Caries / Q000209:etiology*; D003773:Dental Plaque / Q000209:etiology*; D004037:Diet, Cariogenic; D005260:Female; D005459:Fluorides / Q000008:administration & dosage / Q000494:pharmacology*; D006262:Health; D006304:Health Status; D007668:Kidney / Q000378:metabolism; D008274:Magnesium / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013177:Sports
D008274:Magnesium; D005459:Fluorides