title: SCC tumour marker and its relationship to clinical stage in squamous cervical cancer.
abstract: Serum from 103 patients with histologically proven squamous cell cervical carcinoma were analysed for the presence of tumour marker, SCC antigen. Although values ranged between 0.2-109.7 ng/ml the majority of cases (75%) fell below 7.9 ng/ml. There was no relationship between SCC antigen values and clinical stage. The high false negative rate (29%) of this marker in patients with proven disease would preclude its use as a diagnostic screen.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Sydney, Westmead Hospital, New South Wales.
authors.forename: R J
authors.initials: RJ
authors.lastname: Henry
authors.forename: J K
authors.initials: JK
authors.lastname: Dodd
authors.forename: J P
authors.initials: JP
authors.lastname: Tyler
authors.forename: C R
authors.initials: CR
authors.lastname: Houghton
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D005260:Female; D006801:Humans; D011863:Radioimmunoassay; D015843:Serpins; D002583:Uterine Cervical Neoplasms / Q000276:immunology*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D015843:Serpins; C051072:squamous cell carcinoma-related antigen; C036649:tumor antigen TA-4, human