title: Blood group change in a patient with blastic transformation of a myelodysplastic syndrome.
abstract: Loss of certain red blood cell antigens has been described in patients with acute myelocytic leukemia (AML). This paper describes the loss of blood group A antigen in a patient with AML. The acute leukemia in this patient was preceded by a myelodysplastic syndrome for several months. At the time of diagnosis the patient's red cells showed the 0 Rh(D)+ phenotype. After induction of complete remission with two courses of Daunorubicin, Cytosin-arabinosid, and Etoposid his blood group reverted to A2. Serological studies including saliva analysis revealed that the original blood group was very likely A.
authors.forename: N
authors.initials: N
authors.lastname: Xiros
authors.forename: H
authors.initials: H
authors.lastname: Northoff
authors.forename: B
authors.initials: B
authors.lastname: Anger
authors.forename: W
authors.initials: W
authors.lastname: Heit
authors.forename: H
authors.initials: H
authors.lastname: Heimpel
mesh_terms: D000017:ABO Blood-Group System; D000954:Antigens, Surface / Q000032:analysis; D001752:Blast Crisis; D001789:Blood Group Antigens; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000097:blood / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000097:blood* / Q000473:pathology; D012074:Remission Induction
chemical_list: D000017:ABO Blood-Group System; D000954:Antigens, Surface; D001789:Blood Group Antigens