title: Botulinum toxin A induced protective ptosis.
abstract: Botulinum Toxin A injected into the levator palpebrae superioris produces a flaccid ptosis of the upper lid and provides a safe and effective protection for the cornea to aid healing in indolent ulceration or as prophylaxis when there is fifth or seventh cranial nerve damage. Fifteen patients have received this treatment. Levator paresis, producing ptosis for a mean of 2-3 weeks and recovering in a mean of 8.1 weeks was successfully produced in all patients and complete corneal healing was produced in 80% of patients. The major side effect was weakness of the superior rectus muscle which occurred in 80% of cases and lasted a mean of 6 weeks.
authors.affiliation: Department of Clinical Ophthalmology, Moorfields Eye Hospital, London.
authors.forename: G G
authors.initials: GG
authors.lastname: Adams
authors.forename: C M
authors.initials: CM
authors.lastname: Kirkness
authors.forename: J P
authors.initials: JP
authors.lastname: Lee
mesh_terms: D001763:Blepharoptosis / Q000139:chemically induced*; D001905:Botulinum Toxins / Q000627:therapeutic use*; D003320:Corneal Ulcer / Q000188:drug therapy*; D006801:Humans; D013997:Time Factors; D014945:Wound Healing
chemical_list: D001905:Botulinum Toxins