title: Antibacterial activity of enoxacin: comparison with aminoglycosides, beta-lactams and other antimicrobial agents.
abstract: The activity of enoxacin, a new quinolone carboxylic acid, was evaluated against 3014 clinical isolates of Enterobacteriaceae, Pseudomonas and other non-fermenters and Staphylococcus aureus. Comparison was made with gentamicin, tobramycin, amikacin, netilmicin, ampicillin, piperacillin, carbenicillin, ticarcillin, ticarcillin plus clavulanic acid, trimethoprim, cotrimoxazole and erythromycin. In general enoxacin was the most active compound and resistance was only rarely encountered.
authors.forename: R
authors.initials: R
authors.lastname: Vanhoof
authors.forename: J M
authors.initials: JM
authors.lastname: Hubrechts
authors.forename: E
authors.initials: E
authors.lastname: Roebben
authors.forename: M
authors.initials: M
authors.lastname: Claeys
authors.forename: H J
authors.initials: HJ
authors.lastname: Nyssen
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D015365:Enoxacin; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D009287:Naphthyridines / Q000494:pharmacology*; D047090:beta-Lactams
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D009287:Naphthyridines; D047090:beta-Lactams; D015365:Enoxacin