Dephosphorylation of "abp38" protein during the differentiation of mouse myeloid leukemia cells.
We have characterized the phosphorylation of "abp38" before and after the differentiation of mouse myeloid leukemic cells (M1 cells). The abp38 of both undifferentiated and differentiated M1 cells contained phosphoserine and phosphotyrosine. The extent of phosphorylation of abp38 decreased to about 30% of the value of undifferentiated cells during cell differentiation; phosphoserine and phosphotyrosine decreased to 41 and 11% of the values before differentiation, respectively.
Takagi
K
K
Ichikawa
Y
Y
D000199:Actins / Q000378:metabolism; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002454:Cell Differentiation; D002478:Cells, Cultured; D003598:Cytoskeletal Proteins / Q000032:analysis*; D007122:Immunoelectrophoresis; D007951:Leukemia, Myeloid / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D009363:Neoplasm Proteins / Q000032:analysis*; D010761:Phosphorus Radioisotopes; D010766:Phosphorylation; D011233:Precipitin Tests
C052049:ABP 38; D000199:Actins; D000596:Amino Acids; D003598:Cytoskeletal Proteins; D009363:Neoplasm Proteins; D010761:Phosphorus Radioisotopes