title: [Clinical studies on imipenem/cilastatin sodium in pediatric field].
abstract: Clinical studies on imipenem/cilastatin sodium (MK-0787/MK-0791) was carried out in 12 patients in pediatric field. The overall efficacy rate was 83.3%. As for adverse reaction, soft stool was observed in 1 patient. In clinical laboratory findings, there was 1 patient with granulocytopenia.
authors.forename: K
authors.initials: K
authors.lastname: Nagata
authors.forename: M
authors.initials: M
authors.lastname: Yokoyama
authors.forename: A
authors.initials: A
authors.lastname: Ohnishi
authors.forename: Y
authors.initials: Y
authors.lastname: Izumi
mesh_terms: D000293:Adolescent; D000380:Agranulocytosis / Q000139:chemically induced*; D001424:Bacterial Infections / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D015377:Cilastatin; D003521:Cyclopropanes / Q000008:administration & dosage* / Q000009:adverse effects; D004338:Drug Combinations; D005260:Female; D006801:Humans; D015378:Imipenem; D007223:Infant; D008297:Male; D013845:Thienamycins / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D003521:Cyclopropanes; D004338:Drug Combinations; D013845:Thienamycins; D015377:Cilastatin; D015378:Imipenem