[Prognostic factors in cerebral hypoxic-ischemias in infants less than a year old].
In order to establish criteria for early cerebral prognosis after acute cerebral hypoxic ischemic insult, we studied 31 cases of patients presenting, during their first year of life, cardio-respiratory arrests due to SIDS (21 cases), anesthesia (4 cases), other causes (6 cases). A favourable evolution was observed in 5 cases where coma lasted less than 8 hours. Conversely unfavorable evolution was seen in the 26 patients (21 deaths, 5 sequellae) where coma lasted more than 8 hours. Among 12 patients of this group surviving after the 4th day, 9 expressed seizures or status epilepticus. The poor evolution was correlated with hyperproteinorachia during the first 24 hours and with cortico-subcortical hypodensity on CT scan. Early EEG and transfontanellar echography seemed less useful to establish a prognosis, specifically to discriminate children surviving with and without sequelae.
Tardieu
M
M
Département de Pédiatrie, Hôpital de Bicêtre, Le Kremlin.
Devictor
D
D
Wood
C
C
Navelet
Y
Y
Pariente
D
D
Huault
G
G
Landrieu
P
P
D002545:Brain Ischemia / Q000150:complications / Q000503:physiopathology*; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D003402:Creatine Kinase / Q000097:blood; D004453:Echoencephalography; D004569:Electroencephalography; D005260:Female; D006323:Heart Arrest / Q000209:etiology; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications / Q000503:physiopathology*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
D002556:Cerebrospinal Fluid Proteins; D003402:Creatine Kinase
Facteurs pronostiques au cours des hypoxies-ischémies cérébrales du nourrisson de moins de un an.