title: Segregation analyses and gene-centromere distances in zebrafish.
abstract: The gol-1, gol-2, alb-1 and spa-1 mutations affect pigment pattern in the zebrafish. We show here that these loci are unlinked to each other. In addition, gene-centromere distances were determined for these loci by analysis of half-tetrads obtained by the inhibition of the second meiotic division. The fractions of tetratype (second-division segregation) tetrads range from 0.24 (spa-1) to 0.89 (gol-1). The observation of greater than 0.67 second-division segregation indicates that the zebrafish has high chiasma interference.
authors.forename: G
authors.initials: G
authors.lastname: Streisinger
authors.forename: F
authors.initials: F
authors.lastname: Singer
authors.forename: C
authors.initials: C
authors.lastname: Walker
authors.forename: D
authors.initials: D
authors.lastname: Knauber
authors.forename: N
authors.initials: N
authors.lastname: Dower
mesh_terms: D000818:Animals; D002503:Centromere; D002875:Chromosomes; D005399:Fishes / Q000235:genetics*; D008040:Genetic Linkage; D005819:Genetic Markers; D006720:Homozygote; D008126:Lod Score; D009154:Mutation; D010858:Pigmentation; D011995:Recombination, Genetic
chemical_list: D005819:Genetic Markers