title: Children cured of acute lymphoid leukemia. Long-term follow-up studies, including progeny.
abstract: The subject of analysis is a group of 111 children with acute lymphoid leukemia (ALL) whose remission has lasted at least 4 years since stopping treatment. Patients were observed from 4 to 18 years after ALL therapy. No symptoms of disease were observed in 110 children; one child had leukemic infiltration of the testes during the fifth year after stopping treatment. In this group of children no changes in physical development have been recorded, but a growth deficiency is sometimes noted. No symptoms of intrinsic organ lesions have been ascertained in most of the patients. All of the patients, except one with schizophrenia, lead normal lives and either attend school or go to work. Seven patients have healthy children, who were born 6-24 years after the beginning of the disease and 3-16 years after cessation of therapy.
authors.forename: R
authors.initials: R
authors.lastname: Rokicka-Milewska
authors.forename: D
authors.initials: D
authors.lastname: Derulska
authors.forename: J
authors.initials: J
authors.lastname: Armata
authors.forename: W
authors.initials: W
authors.lastname: Balwierz
authors.forename: J
authors.initials: J
authors.lastname: Boguslawska-Jaworska
authors.forename: R
authors.initials: R
authors.lastname: Cyklis
authors.forename: B
authors.initials: B
authors.lastname: Duczmal
authors.forename: D
authors.initials: D
authors.lastname: Michalewska
authors.forename: T
authors.initials: T
authors.lastname: Newecka
authors.forename: M
authors.initials: M
authors.lastname: Ochocka
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D010808:Physical Examination; D011247:Pregnancy