Prodrugs as drug delivery systems. 74. Facile hydrolysis of N-(acyloxymethyl)amide derivatives and implications for the design of prodrugs of NH-acidic compounds and of carboxylic acids.
Bundgaard
H
H
Nielsen
N M
NM
D000588:Amines / Q000032:analysis; D001549:Benzamides / Q000138:chemical synthesis*; D002264:Carboxylic Acids / Q000032:analysis; D002626:Chemistry, Pharmaceutical; D006868:Hydrolysis; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis*; D011355:Prodrugs / Q000138:chemical synthesis*
D000588:Amines; D001549:Benzamides; D002264:Carboxylic Acids; D004364:Pharmaceutical Preparations; D011355:Prodrugs