title: Changes in serum magnesium concentration after strenuous exercise.
abstract: Serum magnesium concentration (S-Mg) was measured in 20 highly trained young men (mean age 19.5, +/- 0.5, range 18-20.5) before, and at 1 hour, 24 hours, 72 hours, and 3 months after a 120 km hike. As found in previous studies, S-Mg was significantly decreased at the end of the hike (p less than 0.001, [corrected] Student's t-test). In this group S-Mg had risen significantly after 24 hours in relation to the value at 1 hour (but not to starting value); yet, at 72 hours and 3 months later, it was once more significantly lower than the starting value (p less than 0.001 and p less than 0.05, respectively, Student's t-test). A marked elevation in serum creatine kinase activity (CK) suggests that the rise in S-Mg observed at 24 hours is the result of either exertional rhabdomyolysis or loss of membrane integrity, as a result of the strenuous exertion, since the CK had fallen sharply by 72 hours after the hike. The biphasic, statistically significant, lowering of S-Mg which persisted after 3 months suggests that strenuous exertion induces magnesium deficiency.
authors.forename: G
authors.initials: G
authors.lastname: Stendig-Lindberg
authors.forename: Y
authors.initials: Y
authors.lastname: Shapiro
authors.forename: Y
authors.initials: Y
authors.lastname: Epstein
authors.forename: E
authors.initials: E
authors.lastname: Galun
authors.forename: E
authors.initials: E
authors.lastname: Schonberger
authors.forename: E
authors.initials: E
authors.lastname: Graff
authors.forename: W E
authors.initials: WE
authors.lastname: Wacker
mesh_terms: D000293:Adolescent; D000328:Adult; D002118:Calcium / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D007700:Kinetics; D008274:Magnesium / Q000097:blood*; D008275:Magnesium Deficiency / Q000209:etiology; D008297:Male; D005082:Physical Exertion
chemical_list: D003402:Creatine Kinase; D008274:Magnesium; D002118:Calcium