Effects of cerebral and myocardial ischemia on diving bradycardia in rats.
The simulated diving in awake rats was performed before, during and after cerebral or myocardial ischemia. Diving bradycardia was attenuated at 1 hr and 3 days, but recovered 7 days after cerebral ischemia. EEG became flat promptly after cerebral ischemia and maintained low amplitude at 1 day, but recovered at 7 days. Diving bradycardia did not change at 1 hr, but was attenuated at 3 and 7 days after myocardial ischemia. A combination of cerebral and myocardial ischemia attenuated diving bradycardia through 1 hr, 3 days and 7 days. The results indicate that either cerebral or myocardial ischemia attenuated diving bradycardia.
Huang
T F
TF
Department of Physiology, National Taiwan University, Taipei, ROC.
Ting
H J
HJ
Chang
P L
PL
Peng
Y I
YI
D000818:Animals; D001794:Blood Pressure; D001919:Bradycardia / Q000209:etiology* / Q000503:physiopathology; D002545:Brain Ischemia / Q000150:complications / Q000473:pathology; D003327:Coronary Disease / Q000150:complications / Q000473:pathology; D004242:Diving / Q000009:adverse effects*; D004569:Electroencephalography; D005260:Female; D006339:Heart Rate; D008297:Male; D051381:Rats; D013997:Time Factors