[Ofloxacin treatment in nephrologic problem patients with various degrees of chronic renal failure (including dialysis treatment). Preliminary results].
Treatment with ofloxacin in 15 patients with chronic renal failure at different stages is reported with respect to patients undergoing hemodialysis treatment. We noticed the elimination of gram-negative and gram-positive strains, even in patients who had extensive but unsuccessful antimicrobial pretreatment. In the reported collective an interaction between ofloxacin and phosphate-binders on aluminum hydroxide basis has to be considered in the individual cases. The dosage of ofloxacin has to be adapted to the stage of chronic renal failure.
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Dörfler
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D000328:Adult; D000368:Aged; D000536:Aluminum Hydroxide / Q000627:therapeutic use; D000892:Anti-Infective Agents, Urinary / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy*; D003404:Creatinine / Q000097:blood; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005921:Glomerulonephritis / Q000188:drug therapy; D006801:Humans; D007676:Kidney Failure, Chronic / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000188:drug therapy; D015242:Ofloxacin; D010078:Oxazines / Q000627:therapeutic use*; D011704:Pyelonephritis / Q000188:drug therapy; D006435:Renal Dialysis; D014552:Urinary Tract Infections / Q000188:drug therapy*
D000892:Anti-Infective Agents, Urinary; D010078:Oxazines; D000536:Aluminum Hydroxide; D015242:Ofloxacin; D003404:Creatinine
Ofloxacin-Behandlung bei nephrologischen Problempatienten mit unterschiedlich ausgeprägter chronischer Niereninsuffizienz (inkl. Dialyse-Behandlung). Vorläufige Ergebnisse.