title: Newer antibiotics: their place in geriatric care. Part I.
abstract: The third-generation cephalosporins offer considerable appeal for treatment of specific life-threatening infections (nosocomial pneumonia, meningitis, urosepsis) in elderly patients when the disorders are caused by aerobic gram-negative bacilli. Despite the frequent presence of cross-reactive antibodies in the sera of recipients of cephalosporins, clinically evident serious reactions to cephalosporins occur infrequently in patients with known penicillin allergy.
authors.forename: R A
authors.initials: RA
authors.lastname: Gleckman
authors.forename: M M
authors.initials: MM
authors.lastname: Bergman
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy*; D002435:Cefamandole / Q000031:analogs & derivatives / Q000627:therapeutic use; D002437:Cefazolin / Q000627:therapeutic use; D015790:Cefonicid; D015313:Cefotetan; D002440:Cefoxitin / Q000627:therapeutic use; D002444:Cefuroxime / Q000627:therapeutic use; D002511:Cephalosporins / Q000494:pharmacology / Q000627:therapeutic use*; D002513:Cephamycins / Q000627:therapeutic use; D005853:Geriatrics; D006801:Humans
chemical_list: D002511:Cephalosporins; D002513:Cephamycins; D015313:Cefotetan; D002435:Cefamandole; D015790:Cefonicid; D002440:Cefoxitin; D002437:Cefazolin; D002444:Cefuroxime