Biochemical investigation of tissue growth: towards definition of "standard" tissue samples.
This paper presents an animal model [the kangaroo], a quantitative anatomical dissection procedure, and a mathematical model [two-phase linear regression] which illustrate that body tissues grow at varying rates relative to each other. An argument is developed that biochemists interested in tissue chemical activity need to be able to sample tissue of known [predicted] growth rate. It is assumed that the ability to select, say muscle tissue samples, from any one animal at a stage of its growth where the individual selected pieces of tissue have known [predicted] low, average and high growth rates would allow comparisons to be made between the sampled tissues that may elucidate the underlying biochemical mechanisms involved in the growth process. It is asserted that to establish standards for tissue samples used in biochemical growth studies, the growth rate of the sampled tissue should be one of the criteria incorporated into the definition of what is "standard" for a tissue sample.
Hopwood
P R
PR
Department of Veterinary Anatomy, University of Sydney, Australia.
Griffiths
D A
DA
D000818:Animals; D001835:Body Weight; D007614:Macropodidae / Q000254:growth & development*; D008394:Marsupialia / Q000254:growth & development*; D008954:Models, Biological; D024510:Muscle Development; D012015:Reference Standards; D014020:Tissue Extracts / Q000502:physiology*
D014020:Tissue Extracts