Modification by S-adenosyl-L-homocysteine of norepinephrine in-vitro uptake in rat brain homogenates.
After incubation of rat brain homogenates with S-adenosyl-L-homocysteine (10 microM), norepinephrine uptake was modified according to the norepinephrine concentration. For low-range concentrations, uptake was lowered, whereas for high-range concentrations, uptake was increased.
Fonlupt
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P
INSERM Unit 205, National Institute of Applied Science at Lyon, Villeurlaurne, France.
Rey
C
C
Pacheco
H
H
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D006710:Homocysteine / Q000031:analogs & derivatives*; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D012435:S-Adenosylhomocysteine / Q000494:pharmacology*
D006710:Homocysteine; D012435:S-Adenosylhomocysteine; D009638:Norepinephrine