title: Pharmacologic treatment of cognitive deficits: a case study.
abstract: Traumatic brain injury (TBI) is associated with a variety of cognitive and behavioural disorders. A few reports have suggested that pharmacotherapy might be useful in the management of these disorders. We present a case of a patient who suffered a left subdural hematoma and herniated. Several months after the injury, his function was severely limited. Nevertheless, he demonstrated a clear improvement in response to oral methylphenidate and parenteral physostigmine. We conclude that specific pharmacotherapy may result in major cognitive and functional improvements in severely impaired patients.
authors.affiliation: Braintree Hospital, Massachusetts.
authors.forename: R M
authors.initials: RM
authors.lastname: Weinberg
authors.forename: S H
authors.initials: SH
authors.lastname: Auerbach
authors.forename: S
authors.initials: S
authors.lastname: Moore
mesh_terms: D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D003072:Cognition Disorders / Q000188:drug therapy* / Q000209:etiology; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use*; D010713:Phosphatidylcholines / Q000627:therapeutic use*; D010830:Physostigmine / Q000627:therapeutic use*
chemical_list: D010713:Phosphatidylcholines; D008774:Methylphenidate; D010830:Physostigmine