Thermal and pH stability of "beta-benzyme".
The thermal and pH stability of "beta-benzyme", an artificial chymotrypsin based on beta-cyclodextrin, has been studied and compared with the stability of real chymotrypsin. Artificial chymotrypsin is vastly superior to real chymotrypsin with regard to both temperature and pH stability. The reasons for this increased stability are discussed.
D'Souza
V T
VT
Lu
X L
XL
Ginger
R D
RD
Bender
M L
ML
D002918:Chymotrypsin / Q000378:metabolism*; D003505:Cyclodextrins / Q000378:metabolism*; D003912:Dextrins / Q000378:metabolism*; D004795:Enzyme Stability; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008956:Models, Chemical; D013213:Starch / Q000378:metabolism*; D013816:Thermodynamics; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D003912:Dextrins; D047392:beta-Cyclodextrins; D013213:Starch; D002918:Chymotrypsin; C051305:chymotrypsin beta-benzyme; C031215:betadex