Behavior of differently sterilized allogenic lyophilized cartilage implants in dogs.
The behavior of beta-propriolactone-sterilized, radiation-sterilized, and gas-sterilized lyophilized cartilage implants was histiologically investigated at various intervals up to 328 days. Beta-propriolactone-sterilized lyophilized cartilage implants were completely resorbed after 230 days and had only undergone partial osseous substitution. The radiation-sterilized lyophilized cartilage implants behaved similarly after 125 days. Despite partial resorption of the gas-sterilized lyophilized cartilage after 328 days, constant form was maintained and complete bony substitution of the resorbed regions had occurred in each case.
Wangerin
K
K
Ewers
R
R
Bumann
A
A
D000818:Animals; D001862:Bone Resorption / Q000473:pathology; D002113:Calcification, Physiologic; D002356:Cartilage / Q000033:anatomy & histology / Q000637:transplantation*; D004202:Disinfectants; D004285:Dogs; D005027:Ethylene Oxide; D005612:Freeze Drying; D005720:Gamma Rays; D010012:Osteogenesis; D011420:Propiolactone; D012272:Ribs; D013242:Sterilization / Q000379:methods*
D004202:Disinfectants; D011420:Propiolactone; D005027:Ethylene Oxide