[Effect of cholesterol on the level of ascorbic acid in the plasma and tissues of rabbits].
Studies were carried out on 10 rabbits divided into two groups. Group I was fed on a physiological diet, group II was given additionally 200 mg of cholesterol daily. After 2 weeks the rabbits were decapitated and, having prepared the tissues according to Zannoni, the level of vitamin C was determined in the plasma, liver and intestinal wall by the method of Roe-Kuenther. It was shown that the diet rich in cholesterol caused a decrease in the level of vitamin C in the organism. The level of ascorbic acid decreased by 57% in the liver and plasms, by 52% in the wall of the caecum, whereas by 30% in the wall of the jejunum. A high level of cholesterol in the organism seems to increase its demand for vitamin C.
Nagórna-Stasiak
B
B
Instytut Nauk Fizjologicznych AR w Lublinie.
Wawrzeńska
M
M
Kopeć
R
R
Lietz
W
W
D000818:Animals; D001205:Ascorbic Acid / Q000097:blood / Q000378:metabolism*; D001206:Ascorbic Acid Deficiency / Q000209:etiology*; D002432:Cecum / Q000378:metabolism; D002791:Cholesterol, Dietary / Q000009:adverse effects*; D007583:Jejunum / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D011817:Rabbits
D002791:Cholesterol, Dietary; D001205:Ascorbic Acid
Wpływ cholesterolu na poziom kwasu askorbowego w osoczu i tkankach królików.