title: [The isocyanates: respiratory pathology].
abstract: Isocyanates are often used in making polyurethanes (foam, varnish, paint, glue). They interest allergists and work physicians. Effects are different according to concentration. In strong concentration they are irritant. In weak concentration they bring on asthma. A long exposure may provoke chronic airway obstruction. Diagnosis is not easy, based on clinical, physiologic and laboratory characteristics. Mechanism is unknown (immunological, irritant, beta-blocking effect).
authors.forename: G
authors.initials: G
authors.lastname: Blandin
authors.forename: B
authors.initials: B
authors.lastname: Fargetton
authors.forename: F
authors.initials: F
authors.lastname: Latil
mesh_terms: D000402:Airway Obstruction / Q000209:etiology / Q000276:immunology*; D001249:Asthma / Q000209:etiology* / Q000276:immunology; D002908:Chronic Disease; D003485:Cyanates / Q000009:adverse effects* / Q000276:immunology; D004342:Drug Hypersensitivity; D006801:Humans; D009784:Occupational Diseases / Q000209:etiology / Q000276:immunology*; D010150:Paint; D011140:Polyurethanes / Q000009:adverse effects; D012130:Respiratory Hypersensitivity / Q000209:etiology / Q000276:immunology*
chemical_list: D003485:Cyanates; D011140:Polyurethanes; C005057:isocyanic acid
vernacular_title: Les isocyanates: pathologie respiratoire.