Activity of the lysosomal cysteine proteinases (cathepsin B,H,L) and a metalloproteinase (MMP-7-ase) in the serum of cystic fibrosis homozygous children.
Lysosomal cysteine proteinase (cathepsin B, H, L) and metalloproteinase (MMP-7-ase) activities were measured from serum of 19 cystic fibrosis (CF) homozygotes and of 13 healthy children, as control group. The activity of cathepsin B and H significantly increased in the CF-group.
László
A
A
Department of Pediatrics, University Medical School, Szeged, Hungary.
Sohár
I
I
Gyurkovits
K
K
D002403:Cathepsins / Q000097:blood*; D002648:Child; D003550:Cystic Fibrosis / Q000201:enzymology* / Q000235:genetics; D006720:Homozygote; D006801:Humans; D008666:Metalloendopeptidases / Q000097:blood*
D002403:Cathepsins; D008666:Metalloendopeptidases