Cutaneous manifestations of Corynebacterium group JK sepsis.
A 14-year-old boy developed group JK corynebacteria sepsis and a generalized erythematous macular and papular skin eruption following chemotherapy for relapse of acute lymphocytic leukemia. Lesional skin biopsy demonstrated effacement of eccrine glands by numerous pleomorphic gram-positive bacilli, morphologically consistent with Corynebacterium and confirmed by culture. This is the first known report documenting the generalized skin manifestations and histopathologic features associated with Corynebacterium sepsis.
Jerdan
M S
MS
Shapiro
R S
RS
Smith
N B
NB
Virshup
D M
DM
Hood
A F
AF
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003354:Corynebacterium Infections / Q000175:diagnosis*; D006801:Humans; D007108:Immune Tolerance; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007945:Leukemia, Lymphoid / Q000188:drug therapy; D008297:Male; D012867:Skin / Q000473:pathology; D012874:Skin Diseases, Infectious / Q000209:etiology*