title: Osteosarcoma as a primary second tumor in a patient with nonhereditary retinoblastoma.
abstract: A case of osteosarcoma of the distal femur 13 years after the occurrence of a unilateral nonhereditary retinoblastoma is reported. The karyotype of circulating lymphocytis was found to be normal. The existence of a linkage between the two neoplasms due to a subtle chromosomal abnormality is discussed.
authors.forename: A
authors.initials: A
authors.lastname: Sudanese
authors.forename: A
authors.initials: A
authors.lastname: Toni
authors.forename: N
authors.initials: N
authors.lastname: Baldini
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000150:complications* / Q000473:pathology; D005134:Eye Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012516:Osteosarcoma / Q000150:complications* / Q000473:pathology; D012175:Retinoblastoma / Q000150:complications* / Q000473:pathology