[Karyotype in fortuitous familial meningioma. Report of 2 cases].
The authors report a case of two sisters affected of intracranial meningioma, with no evidence of von Recklinghausen's disease. A study of the karyotype has been performed in the patients and in their family; in one sister we have found a pericentric inversion of one chromosome 9. The possible role of the chromosomal abnormality in the develop of familial meningioma is discussed.
Acqui
M
M
Dipartimento di Scienze Neurologiche, Cattedra di Neurochirurgia II, Università La Sapienza, Roma.
Mastronardi
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L
Ferrante
L
L
D000328:Adult; D007446:Chromosome Inversion; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D007621:Karyotyping; D008577:Meningeal Neoplasms / Q000235:genetics*; D008579:Meningioma / Q000235:genetics*
Il cariotipo nei meningiomi familiari "occasionali". Osservazione di due casi.