Scanning electron microscopy of fluoride-induced disturbances on the enamel surface of rat molars.
Rats were given a single high dose of fluoride at the age of 5 days and killed after 24 h, 10 or 15 days. The maxillary first molars were prepared for scanning electron microscopic examination. It was concluded that a single dose of fluoride, preferentially affecting ameloblasts with a high secretory activity, leads to the formation of subameloblastic cysts and enamel hypoplasias covered with granular deposits.
Nordlund
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Lindskog
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D000565:Ameloblasts / Q000187:drug effects / Q000648:ultrastructure; D000818:Animals; D003743:Dental Enamel / Q000187:drug effects / Q000648:ultrastructure*; D003744:Dental Enamel Hypoplasia / Q000139:chemically induced* / Q000473:pathology; D008855:Microscopy, Electron, Scanning; D008963:Molar / Q000187:drug effects / Q000648:ultrastructure*; D009807:Odontogenic Cysts / Q000139:chemically induced / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D012969:Sodium Fluoride / Q000009:adverse effects*; D014078:Tooth Eruption
D012969:Sodium Fluoride