Biotransformation of 3-methylphthalate by Micrococcus sp. strain 12B.
When Micrococcus strain 12B grown on o-phthalate was incubated with 3-methylphthalate, three compounds accumulated. These were shown to be 2-pyrone-3-methyl-4,6-dicarboxylic acid, 3,4-dihydroxy-6-methylphthalic acid, and 5-hydroxy-3-methyphthalic acid, all previously undescribed. A pathway for the formation of these compounds is proposed.
Eaton
R W
RW
Department of Microbiology, University of Miami School of Medicine, Florida 33152.
Ribbons
D W
DW
D001711:Biotransformation; D002850:Chromatography, Gel; D008837:Micrococcus / Q000378:metabolism*; D010795:Phthalic Acids / Q000493:pharmacokinetics*
D010795:Phthalic Acids; C055516:3-methylphthalate