Newer antibiotics: their place in geriatric care. Part I.
The third-generation cephalosporins offer considerable appeal for treatment of specific life-threatening infections (nosocomial pneumonia, meningitis, urosepsis) in elderly patients when the disorders are caused by aerobic gram-negative bacilli. Despite the frequent presence of cross-reactive antibodies in the sera of recipients of cephalosporins, clinically evident serious reactions to cephalosporins occur infrequently in patients with known penicillin allergy.
Gleckman
R A
RA
Bergman
M M
MM
D001424:Bacterial Infections / Q000188:drug therapy*; D002435:Cefamandole / Q000031:analogs & derivatives / Q000627:therapeutic use; D002437:Cefazolin / Q000627:therapeutic use; D015790:Cefonicid; D015313:Cefotetan; D002440:Cefoxitin / Q000627:therapeutic use; D002444:Cefuroxime / Q000627:therapeutic use; D002511:Cephalosporins / Q000494:pharmacology / Q000627:therapeutic use*; D002513:Cephamycins / Q000627:therapeutic use; D005853:Geriatrics; D006801:Humans
D002511:Cephalosporins; D002513:Cephamycins; D015313:Cefotetan; D002435:Cefamandole; D015790:Cefonicid; D002440:Cefoxitin; D002437:Cefazolin; D002444:Cefuroxime