title: The subunit I of the respiratory-chain NADH dehydrogenase from Cephalosporium acremonium: the evolution of a mitochondrial gene.
abstract: A Cephalosporium acremonium mitochondrial gene equivalent to human URF1 has been identified. The primary structure of the protein is highly homologous to its human (39%) and A. nidulans (66%) counterparts. Hydrophobicity profiles and predicted secondary structures are also very similar suggesting that this gene codes for the subunit I of the respiratory-chain NADH dehydrogenase. The nucleotide sequence of the gene, 70% homologous to the A. nidulans one, presents a high AT content (72%) and this fact is reflected in the codon usage.
authors.affiliation: Laboratorio de Genética Molecular, Antibióticos S.A., Madrid, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Peñalva
authors.forename: J L
authors.initials: JL
authors.lastname: García
mesh_terms: D000164:Acremonium / Q000201:enzymology / Q000235:genetics*; D001483:Base Sequence; D005075:Biological Evolution; D003579:Cytochrome Reductases / Q000235:genetics*; D004271:DNA, Fungal / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D005800:Genes, Fungal; D006801:Humans; D008969:Molecular Sequence Data; D009245:NADH Dehydrogenase / Q000235:genetics*; D011487:Protein Conformation
chemical_list: D004271:DNA, Fungal; D004272:DNA, Mitochondrial; D003579:Cytochrome Reductases; D009245:NADH Dehydrogenase