In vivo bovine enamel remineralization and fluoride uptake from two dentifrices containing different fluoride concentrations.
In this study, the differences in lesion remineralization and fluoride uptake after brushing with a 300 ppm F or a 1000 ppm F dentifrice (as NaF) were investigated. Twenty volunteers with partial dentures in their lower jaws were divided into two groups. Bovine enamel slabs with artificial lesions were mounted in the dentures. After a test period of six weeks, the slabs were taken out and analyzed. There was no statistically significant difference between the two groups, in F-uptake and susceptibility of the enamel to demineralization, although the findings favored the 1000 ppm F toothpaste. The microradiograms in the 300 ppm F group showed lesions more pronounced than those in the 1000 ppm group. The present study cannot support the presumption that the fluoride content of regular NaF dentifrices can be lowered to 300 ppm F without undesirable effects on lesion arrest and remineralization.
De Kloet
H J
HJ
Exterkate
R A
RA
Rempt
H E
HE
Ten Cate
J M
JM
D000328:Adult; D000818:Animals; D002417:Cattle; D003731:Dental Caries / Q000378:metabolism / Q000503:physiopathology; D003743:Dental Enamel / Q000032:analysis / Q000378:metabolism*; D003747:Dental Enamel Solubility / Q000187:drug effects; D003802:Dentifrices / Q000627:therapeutic use*; D005260:Female; D005459:Fluorides / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008903:Minerals / Q000032:analysis; D014089:Tooth Remineralization
D003802:Dentifrices; D008903:Minerals; D005459:Fluorides