title: HLA type and survival in gastric cancer.
abstract: We studied HLA typing of 17 stage III gastric cancer patients who survived for more than 5 years after gastrectomy, in comparison with normal healthy controls and other gastric cancer patients. As a result, the long-term survivors had a high frequency of HLA-DR4 antigen compared with normal healthy controls (P less than 0.0025). This remains statistically significant after correction of the P value according to the number of HLA-DR antigens tested (corrected P value, less than 0.025), strongly suggesting that the presence of this antigen is associated with long-term survival time for postoperative stage III gastric cancer patients.
authors.forename: R
authors.initials: R
authors.lastname: Hayashi
authors.forename: T
authors.initials: T
authors.lastname: Ochiai
mesh_terms: D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000235:genetics; D006801:Humans; D010641:Phenotype; D011379:Prognosis; D013274:Stomach Neoplasms / Q000235:genetics / Q000276:immunology*
chemical_list: D006680:HLA Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II