title: Length polymorphisms of the human Y chromosome in patients with chronic myelogenous leukemia.
abstract: The extent of length heteromorphisms of the human Y chromosomes was measured in 50 patients with chronic myelogenous leukemia and was compared with 50 normal controls. No significant difference (p greater than 0.05) in the size of the Y chromosome was noted between these two groups. These findings differ from an earlier investigation, where a longer heterochromatic segment of Y chromosome was noted in malignant tumors and it was stressed that constitutive heterochromatin plays a role in susceptibility of cancer. Present investigation, however, suggests that this is not the case in patients with chronic myelogenous leukemia.
authors.forename: R S
authors.initials: RS
authors.lastname: Verma
authors.forename: S
authors.initials: S
authors.lastname: Thomas
authors.forename: M
authors.initials: M
authors.lastname: Coleman
authors.forename: R T
authors.initials: RT
authors.lastname: Silver
authors.forename: H
authors.initials: H
authors.lastname: Dosik
mesh_terms: D006570:Heterochromatin / Q000235:genetics*; D006801:Humans; D007951:Leukemia, Myeloid / Q000235:genetics*; D008297:Male; D011110:Polymorphism, Genetic; D014998:Y Chromosome
chemical_list: D006570:Heterochromatin