Echo Doppler assessment of cardiac output and its relation to growth in normal infants.
In a study of 38 normal infants, serial measurements of systemic (n = 169) and pulmonary (n = 143) blood flow were undertaken from the ages of 2 weeks to 12 months by 2-dimensional, M-mode and pulsed Doppler echocardiography. Cardiac output changed linearly (cardiac output = 0.3 X height -0.99 liter/min), and cardiac index was validated as a means for standardizing cardiac output in infants younger than 10 to 13 months of age. Infants younger than 2 months had lower cardiac indexes and stroke volume indexes (2.6 +/- 0.7 liters/min/m2 and 19 +/- 5 ml/m2, respectively) compared with those aged 12 months (3.2 +/- 0.7 liter/min/m2 and 25 +/- 5 ml/m2, respectively). Changes in cardiac output in individual infants over time suggest nonmorphometric modulating factors for cardiovascular function.
Sholler
G F
GF
Adolph Basser Institute of Cardiology, Children's Hospital, Camperdown, Sydney, Australia.
Celermajer
J M
JM
Whight
C M
CM
Bauman
A E
AE
D000367:Age Factors; D001011:Aorta / Q000502:physiology; D001783:Blood Flow Velocity; D001827:Body Height; D002302:Cardiac Output; D004452:Echocardiography; D006128:Growth; D006321:Heart / Q000502:physiology*; D006339:Heart Rate; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008137:Longitudinal Studies; D011651:Pulmonary Artery / Q000502:physiology; D013318:Stroke Volume