title: Association of viral hepatitis A with HLA-A9.
abstract: HLA-A and B phenotyping was carried out, during a viral hepatitis A (VHA) epidemic in Brazil, on 47 unrelated patients with VHA and 53 unrelated healthy subjects of the same age, sex, social status, and ethnic origin. An increased frequency of HLA-A9 (44.7% vs. 15.1%) and a decrease of that of HLA-A3 (2.1% vs. 22.6%) were observed when compared with controls. After correction for the number of antigens tested, only the positive association with HLA-A9 was observed. It was found that the relative risk for an HLA-A9 carrier to develop VHA was 4.5.
authors.forename: B
authors.initials: B
authors.lastname: Arce-Gomez
authors.forename: R A
authors.initials: RA
authors.lastname: Moliterno
authors.forename: A L
authors.initials: AL
authors.lastname: Rodrigues
authors.forename: J
authors.initials: J
authors.lastname: Barbosa
authors.forename: M R
authors.initials: MR
authors.lastname: deOliveira
authors.forename: J C
authors.initials: JC
authors.lastname: Abreu
authors.forename: V A
authors.initials: VA
authors.lastname: SpeckdoNascimento
authors.forename: M G
authors.initials: MG
authors.lastname: Sasaki
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006506:Hepatitis A / Q000235:genetics*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010641:Phenotype
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; C037709:HLA-A9 antigen; D015235:HLA-B Antigens