Clinical applications for an inexpensive, microcomputer-based DNA-cytometry system.
Some of the clinical capabilities of an inexpensive, microcomputer-based DNA-cytometry system are described. A variety of applications is illustrated: ploidy assessment, which provides significant information for the management of patients with tumors from almost any organ site; quality control of cytologic and histologic diagnoses; determination of tumor heterogeneity; monitoring of cell profile changes during therapy; and quantitation of immunocytochemical staining.
Bibbo
M
M
Dytch
H E
HE
Puls
J H
JH
Bartels
P H
PH
Wied
G L
GL
D000328:Adult; D001943:Breast Neoplasms / Q000378:metabolism; D002277:Carcinoma / Q000378:metabolism; D003201:Computers / Q000191:economics; D004247:DNA / Q000378:metabolism*; D005260:Female; D005434:Flow Cytometry / Q000295:instrumentation*; D006801:Humans; D008297:Male; D008838:Microcomputers / Q000191:economics; D008875:Middle Aged; D009369:Neoplasms / Q000235:genetics / Q000473:pathology; D011003:Ploidies; D011247:Pregnancy; D011379:Prognosis; D011960:Receptors, Estrogen / Q000378:metabolism; D002577:Uterine Cervical Diseases / Q000235:genetics / Q000628:therapy
D011960:Receptors, Estrogen; D004247:DNA