title: Structure determination of kanglemeisu A by X-ray diffraction method.
abstract: Kanglemeisu A (C50H63O19B.CH3OH) is the product of an actinomyces species from a soil sample gathered in China Kanglemeisu A belongs to the triclinic system, space group P1, unit cell: a = 12.760(3), b = 10.287(2), c = 9.926(2) A, alpha = 88.39(2), beta = 78.64(2), gamma = 89.14(2). RANTAN direct method is used to solve the structure. The final discrepancy factor is R = 0.0689, after atom coordinates and temperature factors have been refined with full matrix least squares. The structure skeleton consists of four parts, the naphthalene nucleus connected to the 5-membered ring, a 17-membered ring connected to C2, a dimethyl butane diacid extended out from C20, beta-D-3,4-OO' methylenedigitoxose passing through an oxygen bridge O6 and linked to C27 of ansa ring.
authors.affiliation: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing.
authors.forename: G H
authors.initials: GH
authors.lastname: Bao
authors.forename: C H
authors.initials: CH
authors.lastname: He
authors.forename: C F
authors.initials: CF
authors.lastname: Xu
authors.forename: J X
authors.initials: JX
authors.lastname: Yao
authors.forename: N J
authors.initials: NJ
authors.lastname: Wang
authors.forename: S T
authors.initials: ST
authors.lastname: Mu
authors.forename: Q T
authors.initials: QT
authors.lastname: Zheng
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D008968:Molecular Conformation; D012294:Rifamycins / Q000032:analysis*; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D012294:Rifamycins; C055558:kanglemycin A