Effect of activated charcoal on endotoxin adsorption. Part I. An in vitro study.
An in vitro study by using cross-linked agarose coated activated charcoal (CAAC-II) as adsorbent was conducted. Endotoxin was quantitatively measured by chromogenic method of limulus lysate test. Results of the study demonstrated that endotoxin was fairly efficiently removed by CAAC-II. It may therefore be possible for effective adsorption of endotoxin in vivo studies and warrant further experimental study for CAAC-II hemoperfusion in clinical endotoxemia.
Du
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XN
Artificial Liver Research Laboratory, Chongqing University of Medical Sciences, Sichuan, China.
Niu
Z
Z
Zhou
G Z
GZ
Li
Z M
ZM
D000327:Adsorption; D002606:Charcoal; D004731:Endotoxins / Q000097:blood / Q000302:isolation & purification*; D006464:Hemoperfusion; D006801:Humans; D066298:In Vitro Techniques
D004731:Endotoxins; D002606:Charcoal