title: [The average duration of nocturnal reflux in the prognosis of respiratory problems associated with gastroesophageal reflux].
abstract: Choice of therapeutic approach remains difficult in patients with gastro-oesophageal reflux and respiratory symptoms. Except in children in whom microaspiration has been demonstrated it is very difficult to predict which ones are going to be relieved from their respiratory disease after GER treatment. In 1981 Jolley and coll. found that the mean duration of nocturnal episodes of reflux (MDNR) in extended pH-metering excluding post-cibal hours could differentiate not only patients with and without respiratory manifestations, but also those in whom respiratory tract disease will disappear after GER treatment from those in whom this will be useless. Only some references on this topic have been published ever since. We have reviewed the charts and pH tracings of the 70 patients with respiratory disease and GER treated in our service aiming at assessing the real value of this parameter in our hands. Fifty-two cases could be evaluated: 41/52 were either improved or completely relieved from their respiratory manifestations (79%) where has the remaining 21% were unchanged by GER treatment. In the first group MDNR was 13.1 +/- 9.7 min and in the second one it was 6.3 +/- 4.6 (p less than 0.05). Our results confirm that MDNR is a valid parameter in order to make prognosis in this particular group of patients.
authors.affiliation: Universidad del País Vasco, Hospital Materno-Infantil, San Sebastián, Espagne.
authors.forename: I
authors.initials: I
authors.lastname: Eizaguirre
authors.forename: J A
authors.initials: JA
authors.lastname: Tovar
authors.forename: J
authors.initials: J
authors.lastname: Arana
authors.forename: J
authors.initials: J
authors.lastname: Garay
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D005764:Gastroesophageal Reflux / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D011379:Prognosis; D012140:Respiratory Tract Diseases / Q000209:etiology / Q000628:therapy*
vernacular_title: La durée moyenne du reflux nocturne dans le pronostic des problèmes respiratoires associés au reflux gastro-oesophagien.