title: [Use of mucolytic agents and guaran Hepart (HP-7000) for imaging mucosal villi in double-contrast studies of the small intestine].
abstract: It was the aim of this study to enhance the visualisation of mucosal villi by double contrast barium studies of the small bowel. Prior to the radiological examination a 2-day pretreatment with the mucolytic agents acetylcysteine or carbocisteine was effected. Double contrast studies were performed with a high-molecular fraction of guaran HEPART (HP-7000), a hydrocolloid isolated from the seed endosperm of C. tetragonolobus added into contrast-medium and distention medium. Compared to double contrast studies without mucolytic therapy, this procedure results in a better transparency and demonstration of the mucosal villi shown by a granular pattern in the radiographs. High quality visualisation of intestinal villi was achieved in all patients studied. A 2-day pretreatment with carbocisteine or acetylcysteine and the use of guaran in the double contrast barium study of the small bowel results in a greatly enhanced visualisation of mucosal villi.
authors.affiliation: Röntgenabteilung Innere Medizin, Universität Giessen.
authors.forename: J F
authors.initials: JF
authors.lastname: Desaga
mesh_terms: D000111:Acetylcysteine / Q000008:administration & dosage; D000328:Adult; D001466:Barium Sulfate; D002233:Carbocysteine / Q000008:administration & dosage; D003424:Crohn Disease / Q000000981:diagnostic imaging*; D005100:Expectorants / Q000008:administration & dosage*; D005685:Galactans; D006801:Humans; D007413:Intestinal Mucosa / Q000000981:diagnostic imaging*; D007414:Intestinal Neoplasms / Q000000981:diagnostic imaging*; D007421:Intestine, Small / Q000000981:diagnostic imaging*; D008351:Mannans; D053149:Plant Gums; D011134:Polysaccharides; D011859:Radiography
chemical_list: D005100:Expectorants; D005685:Galactans; D008351:Mannans; D053149:Plant Gums; D011134:Polysaccharides; D001466:Barium Sulfate; D002233:Carbocysteine; C007894:guar gum; D000111:Acetylcysteine
vernacular_title: Verwendung von Mukolytika und Guran HEPART (HP-7000) für die Darstellung der Schleimhautzotten bei der Doppelkontrastuntersuchung des Dünndarms.