4'-Thioadenosine as a novel inhibitor of S-adenosylhomocysteine hydrolase and an inducer for the differentiation of HL-60 human leukemia cells.
Miura
G A
GA
Gordon
R K
RK
Montgomery
J A
JA
Chiang
P K
PK
D000241:Adenosine / Q000031:analogs & derivatives* / Q000494:pharmacology; D043383:Adenosylhomocysteinase; D002454:Cell Differentiation / Q000187:drug effects; D002460:Cell Line; D002851:Chromatography, High Pressure Liquid; D006710:Homocysteine / Q000031:analogs & derivatives*; D006801:Humans; D006867:Hydrolases / Q000037:antagonists & inhibitors*; D015470:Leukemia, Myeloid, Acute / Q000201:enzymology / Q000473:pathology; D011685:Purine Nucleotides / Q000378:metabolism; D012435:S-Adenosylhomocysteine / Q000378:metabolism*; D012436:S-Adenosylmethionine / Q000031:analogs & derivatives / Q000378:metabolism; D013872:Thionucleosides / Q000494:pharmacology*
D011685:Purine Nucleotides; D013872:Thionucleosides; D006710:Homocysteine; C050070:4'-thioadenosine; D012436:S-Adenosylmethionine; D012435:S-Adenosylhomocysteine; D006867:Hydrolases; D043383:Adenosylhomocysteinase; D000241:Adenosine