The effect of 13-cis-retinoic acid on wound healing in dogs.
13-cis-retinoic acid is currently accepted as a valuable treatment for patients with severe nodulocystic acne. Many of these individuals express interest in surgical scar-correcting procedures. To ascertain the effect of 13-cis-retinoic acid on wound healing, sequential biopsies were examined from partial and full-thickness wounds in dogs following a 2-month course of retinoids. No significant difference was histologically observed from the control animal.
Dzubow
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Miller
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D000818:Animals; D003869:Dermabrasion; D004285:Dogs; D005260:Female; D015474:Isotretinoin; D012867:Skin / Q000187:drug effects / Q000473:pathology; D014212:Tretinoin / Q000494:pharmacology*; D014945:Wound Healing / Q000187:drug effects*
D014212:Tretinoin; D015474:Isotretinoin