Neonatal rotavirus infection in urban and rural communities in Nigeria.
Two hundred and thirteen neonates from an urban and a rural community in Nigeria were examined for neonatal rotavirus infection. Twenty-four (11%) were shedding rotavirus in their stools. All newborns shedding rotavirus were either asymptomatic or had very mild diarrhoea. Most infections (71%) were detected during the first week of life; 21% and 8% occurred in the second and third weeks respectively. ELISA subgrouping of the rotavirus strains obtained from these neonates showed that 30% belonged to subgroup I and 70% to subgroup II. A survey for rotavirus antibody in a revealed that 67% of these children had antibody in their cord sera. Most of the newborns shedding rotavirus in stool had passively acquired antibody in their sera.
Fagbami
A H
AH
Department of Virology, College of Medicine, University of Ibadan, Nigeria.
Oyejide
C O
CO
Enahoro
F
F
D000914:Antibodies, Viral / Q000032:analysis; D001724:Birth Weight; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000382:microbiology; D005312:Fetal Blood / Q000032:analysis; D006262:Health; D006801:Humans; D007231:Infant, Newborn; D009549:Nigeria; D012400:Rotavirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D012423:Rural Health; D014504:Urban Health
D000914:Antibodies, Viral