title: Clinical and histologic aspects of chronic delta hepatitis.
abstract: Clinical and histologic valuation of delta chronic hepatitis is performed by a comparison between 46 HDV markers seropositive patients and an analogous group of HBsAg seropositive and delta system negative patients. It is possible to point out a greater seriousness of clinical and biohumoral situation during a HDV induced disease which is joined up with a more marked histologic damage and a greater inflammatory activity. The presence of specific viral antigen in hepatocyte nucleus suggests a delta-virus direct cytopathic effect.
authors.affiliation: 2. Department of Infectious Diseases L. Sacco Hospital, Milano, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Viganò
authors.forename: L
authors.initials: L
authors.lastname: Valsecchi
authors.forename: R
authors.initials: R
authors.lastname: Morelli
authors.forename: P
authors.initials: P
authors.lastname: Meraviglia
authors.forename: A
authors.initials: A
authors.lastname: Cargnel
mesh_terms: D000328:Adult; D001247:Asthenia / Q000150:complications; D001835:Body Weight; D003588:Cytopathogenic Effect, Viral; D004415:Dyspepsia / Q000150:complications; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D003699:Hepatitis D / Q000150:complications / Q000473:pathology*; D006801:Humans; D019966:Substance-Related Disorders / Q000150:complications
chemical_list: D006514:Hepatitis B Surface Antigens