Synthesis of 14 beta-cholesta-5,7-dien-3 beta-ol.
5,7-Cholestadien-3 beta-ol was transformed into 14 beta-cholesta-5,7-dien-3 beta-ol in six steps. The inversion of the stereochemistry at C-14 was obtained by a selective protection of the delta 5 and the elaboration of the delta 7 double bond.
Anastasia
M
M
Dipartimento di Chimica e Biochimica Medica, Facoltà di Medicina e Chirurgia, Università di Milano, Italy.
Allevi
P
P
Ciuffreda
P
P
Fiecchi
A
A
Scala
A
A
D055598:Chemical Phenomena; D002621:Chemistry; D002775:Cholestadienols / Q000138:chemical synthesis*; D003684:Dehydrocholesterols / Q000138:chemical synthesis*; D008722:Methods; D013237:Stereoisomerism
D002775:Cholestadienols; D003684:Dehydrocholesterols