title: Recent trends in incidence and mortality rates for leukemias, and in survival rates for childhood acute lymphocytic leukemia, in Upstate New York.
abstract: Analysis of mortality rates for all childhood (age less than 20 years) leukemias in upstate New York showed declines between 1969-1971 and 1978-1980 for ages 0-4 and 5-9 years, while data from a population-based cancer registry for a population of about 10.5 million indicated no decline in incidence rates. Survival rates were examined for 552 children diagnosed with acute lymphocytic leukemia (ALL) in 1973-1980 at less than 15 years of age. There was some evidence for improvement in survival rates over these years of diagnosis, especially among children diagnosed at ages 1-4 and 10-14 years. Hazard rates increased among cases (especially males) diagnosed in 1979 and 1980, however, and this finding requires confirmation from other studies; the possible effect of influenza epidemics also should be explored. Only one confirmed second primary cancer, a rhabdomyosarcoma of the eye, was ascertained (as of the end of 1983), but longer follow-up is needed on children with ALL.
authors.forename: A P
authors.initials: AP
authors.lastname: Polednak
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000453:epidemiology* / Q000401:mortality; D007945:Leukemia, Lymphoid / Q000401:mortality*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology; D009518:New York; D011379:Prognosis; D012042:Registries; D012737:Sex Factors