title: Corneal ulcers associated with cosmetic extended wear soft contact lenses.
abstract: In 52 patients with a history of using cosmetic extended wear soft contact lenses, corneal ulcers developed requiring admission to Wills Eye Hospital between January 1, 1982, and June 30, 1986. A retrospective study was conducted to determine the contact lens history, clinical presentation, culture and sensitivity results, and final visual acuity of these patients. Pseudomonas organisms were isolated in 75% of culture-positive cases. The final visual acuity was 6/60 or less in 12% of all cases and 25% of the Pseudomonas ulcers. Patients and practitioners must be aware of this vision-threatening problem in patients wearing cosmetic extended wear lenses. The pathogenesis of corneal ulcers in contact lens patients has not been established. There may be an inherent increased risk in the use of extended wear, compared to daily wear, soft contact lenses for cosmetic purposes.
authors.forename: E J
authors.initials: EJ
authors.lastname: Cohen
authors.forename: P R
authors.initials: PR
authors.lastname: Laibson
authors.forename: J J
authors.initials: JJ
authors.lastname: Arentsen
authors.forename: C S
authors.initials: CS
authors.lastname: Clemons
mesh_terms: D000293:Adolescent; D000328:Adult; D001419:Bacteria / Q000302:isolation & purification; D002648:Child; D003262:Contact Lenses, Extended-Wear / Q000009:adverse effects*; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D003320:Corneal Ulcer / Q000209:etiology* / Q000382:microbiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011549:Pseudomonas / Q000302:isolation & purification; D011552:Pseudomonas Infections / Q000382:microbiology; D012189:Retrospective Studies; D014792:Visual Acuity