[Population-genetic study of the blood lipids of the aboriginal population of the Obian North].
Lipid metabolism (total cholesterol, triglycerides, and high-density lipoprotein cholesterol) was shown to be dependent on age, while the atherogenic coefficient was unrelated to age both in males and females. Heritability coefficients have been calculated for the above-mentioned parameters on the basis of intrafamilial correlations analysis. Interclass coefficients of the parent-parent correlations suggest the absence of common environmental effects. Significant associations of all three with phenylthiocarbamide, and of hypertriglyceridemia with phenotype MN (p less than 0.05) were demonstrated in females. The determination coefficient has shown the PTC and MN to make the greatest contribution to blood lipid variability.
Puzyrev
V P
VP
Panfilov
V I
VI
Lemza
S V
SV
Kanskaia
N V
NV
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005006:Ethnicity; D005260:Female; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012800:Siberia; D014280:Triglycerides / Q000097:blood
D008078:Cholesterol, LDL; D005819:Genetic Markers; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol
Populiatsionno-geneticheskoe issledovanie lipidov u korennogo naseleniia Obskogo Severa.