title: Effect of activated charcoal on endotoxin adsorption. Part I. An in vitro study.
abstract: An in vitro study by using cross-linked agarose coated activated charcoal (CAAC-II) as adsorbent was conducted. Endotoxin was quantitatively measured by chromogenic method of limulus lysate test. Results of the study demonstrated that endotoxin was fairly efficiently removed by CAAC-II. It may therefore be possible for effective adsorption of endotoxin in vivo studies and warrant further experimental study for CAAC-II hemoperfusion in clinical endotoxemia.
authors.affiliation: Artificial Liver Research Laboratory, Chongqing University of Medical Sciences, Sichuan, China.
authors.forename: X N
authors.initials: XN
authors.lastname: Du
authors.forename: Z
authors.initials: Z
authors.lastname: Niu
authors.forename: G Z
authors.initials: GZ
authors.lastname: Zhou
authors.forename: Z M
authors.initials: ZM
authors.lastname: Li
mesh_terms: D000327:Adsorption; D002606:Charcoal; D004731:Endotoxins / Q000097:blood / Q000302:isolation & purification*; D006464:Hemoperfusion; D006801:Humans; D066298:In Vitro Techniques
chemical_list: D004731:Endotoxins; D002606:Charcoal