title: Acute effect of ethanol administration on platelet function.
abstract: The acute effect of single dose of ethanol (1.5 g kg) and aspirin (10 mg/kg) alone and in combination, on platelet aggregation time and platelet adhesiveness were studied in rabbits. There was a significant and comparable increase in aggregation time both by aspirin and ethanol. Similarly platelet adhesiveness was decreased by both the agents.
authors.affiliation: Department of Pharmacology and Blood Bank, Medical College, Haryana.
authors.forename: S
authors.initials: S
authors.lastname: Sudhir
authors.forename: L C
authors.initials: LC
authors.lastname: Gupta
authors.forename: J
authors.initials: J
authors.lastname: Singh
authors.forename: R D
authors.initials: RD
authors.lastname: Budhiraja
mesh_terms: D000818:Animals; D001241:Aspirin / Q000494:pharmacology; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D008297:Male; D010973:Platelet Adhesiveness / Q000187:drug effects*; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits
chemical_list: D000431:Ethanol; D001241:Aspirin