[Synthetic studies of polyene macrolide antibiotics. 2. Synthesis of methyl-4,6-dideoxy-2,3-isopropylidene-4-C-methyl-alpha-L- mannopyranoside].
The synthesis of methyl 4,6-dideoxy-2,3-O-isopropylidene-4-C-methyl-alpha-L-mannopyranoside, a key intermediate on the preparation of C33-C38 fragment of amphotericin B, from L-rhamnose is described.
Romanovich
A Iu
AIu
Chizhov
O S
OS
Sviridov
A F
AF
D000666:Amphotericin B / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D008766:Methylmannosides / Q000138:chemical synthesis; D008968:Molecular Conformation; D011090:Polyenes / Q000138:chemical synthesis; D013237:Stereoisomerism
D008766:Methylmannosides; D011090:Polyenes; C055812:methyl-4,6-dideoxy-2,3-O-isopropylidene-4-methylpyranoside; D000666:Amphotericin B
Sinteticheskie issledovaniia v riadu polienovykh makrolidnykh antibiotikov. 2. Sintez metil-4,6-didezoksi-2,3-O-izopropiliden-4-C-metil-alpha-L- mannopiranozida.