title: Paracoccidioidin sensitization in Guyana--a preliminary skin test survey in hospitalized patients and laboratory workers.
abstract: Thirty-one percent of a group of 49 hospitalized patients or laboratory workers in Guyana showed positive intradermal paracoccidioidin tests in the presence of negative histoplasmin reactions. In 2 patients (4%), the intradermal reactions to paracoccidioidin were greater than 10 mm in diameter. The prevalence of positive reactors in a selected population suggests that paracoccidioidomycosis may be endemic in Guyana although no clinical case has been reported from the country. A further survey in a larger, unselected population would lead to a clearer understanding of the problem.
authors.affiliation: London School of Hygiene and Tropical Medicine.
authors.forename: R J
authors.initials: RJ
authors.lastname: Hay
authors.forename: P
authors.initials: P
authors.lastname: Rose
authors.forename: T R
authors.initials: TR
authors.lastname: Jones
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003046:Coccidioidin / Q000276:immunology; D005260:Female; D005656:Fungal Proteins; D006172:Guyana; D006659:Histoplasmin / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010229:Paracoccidioidomycosis / Q000276:immunology*; D012882:Skin Tests
chemical_list: D005656:Fungal Proteins; C008765:paracoccidioidin; D003046:Coccidioidin; D006659:Histoplasmin