title: Necrotizing sialometaplasia obscuring an underlying malignancy: report of a case.
abstract: Necrotizing sialometaplasia poses many diagnostic problems, both clinically and microscopically. Caution had most frequently been urged for distinguishing between malignancy and NS, so as to avoid mutilating surgical treatment resulting from the misdiagnosis of a lesion that is benign and self-limiting. This case has been presented to alert the practitioner to the possibility that NS may obscure an underlying malignant disease process, possibly resulting in delays in referral or treatment. The exceedingly rapid growth of this mesenchymal neoplasm may have caused obstruction of the blood supply to the overlying mucosa and submucosa, thereby producing the ischemic alterations observed in the first biopsy specimens. Some of the difficulties encountered in the detection and diagnosis of neoplasms arising in the parapharyngeal space were discussed, and some previously published suggestions to aid in these efforts were reiterated.
authors.forename: T C
authors.initials: TC
authors.lastname: Poulson
authors.forename: R O
authors.initials: RO
authors.lastname: Greer
authors.forename: R W
authors.initials: RW
authors.lastname: Ryser
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008637:Mesenchymoma / Q000473:pathology; D010614:Pharynx; D012208:Rhabdomyosarcoma / Q000473:pathology*; D012466:Salivary Gland Diseases / Q000473:pathology*; D012797:Sialometaplasia, Necrotizing / Q000473:pathology*