Pharmacologic treatment of cognitive deficits: a case study.
Traumatic brain injury (TBI) is associated with a variety of cognitive and behavioural disorders. A few reports have suggested that pharmacotherapy might be useful in the management of these disorders. We present a case of a patient who suffered a left subdural hematoma and herniated. Several months after the injury, his function was severely limited. Nevertheless, he demonstrated a clear improvement in response to oral methylphenidate and parenteral physostigmine. We conclude that specific pharmacotherapy may result in major cognitive and functional improvements in severely impaired patients.
Weinberg
R M
RM
Braintree Hospital, Massachusetts.
Auerbach
S H
SH
Moore
S
S
D000328:Adult; D001930:Brain Injuries / Q000150:complications*; D003072:Cognition Disorders / Q000188:drug therapy* / Q000209:etiology; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use*; D010713:Phosphatidylcholines / Q000627:therapeutic use*; D010830:Physostigmine / Q000627:therapeutic use*
D010713:Phosphatidylcholines; D008774:Methylphenidate; D010830:Physostigmine