Mapping through somatic cell hybrids and cDNA probes of protein C to chromosome 2, factor X to chromosome 13, and alpha 1-acid glycoprotein to chromosome 9.
The previously unassigned gene coding for the anti-coagulatory protein C has been mapped on chromosome 2 using a cDNA probe and genomic blots from a human-hamster somatic cell hybrid panel. The assignments of the genes coding for the coagulation factor X to chromosome 13, and for alpha 1-acid glycoprotein to chromosome 9 have been confirmed using a similar direct approach.
Rocchi
M
M
Roncuzzi
L
L
Santamaria
R
R
Archidiacono
N
N
Dente
L
L
Romeo
G
G
D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D002882:Chromosomes, Human, Pair 13; D002889:Chromosomes, Human, Pair 2; D002899:Chromosomes, Human, Pair 9; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000235:genetics; D005170:Factor X / Q000235:genetics*; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D009961:Orosomucoid / Q000235:genetics*; D011486:Protein C / Q000235:genetics*
D005819:Genetic Markers; D009961:Orosomucoid; D011486:Protein C; D005170:Factor X; D004247:DNA