Morphological changes in the liver due to phenazone and its derivatives.
Hepatic lesions due to toxic pyrazolone actions are very rare. Relevant observations and reports are reviewed and compared with liver injury caused by other analgesics.
Altmann
H W
HW
D000983:Antipyrine / Q000031:analogs & derivatives / Q000633:toxicity*; D056486:Chemical and Drug Induced Liver Injury; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced / Q000473:pathology; D005234:Fatty Liver / Q000139:chemically induced / Q000473:pathology; D006099:Granuloma / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology; D009336:Necrosis; D010653:Phenylbutazone / Q000633:toxicity
D010653:Phenylbutazone; D000983:Antipyrine