ATP stimulates binding of retinol-cellular retinol binding protein complex to DNA-cellulose.
In calf uterus cytosol a cellular retinol-binding protein (cRBP) was detected which was found to bind to DNA-cellulose. The binding to DNA-cellulose could be enhanced by ATP in a dose-dependent manner. ATP treatment did not change the physico-chemical properties of the retinol-cRBP complex. Our findings suggest a role for ATP in the binding of retinol-cRBP complex to DNA.
Gmeiner
B
B
Institute of Tumorbiology, University of Vienna, Austria.
Zerlauth
G
G
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000378:metabolism; D002482:Cellulose / Q000031:analogs & derivatives* / Q000378:metabolism; D002499:Centrifugation, Density Gradient; D003600:Cytosol / Q000378:metabolism; D004247:DNA / Q000031:analogs & derivatives* / Q000378:metabolism; D005260:Female; D066298:In Vitro Techniques; D012177:Retinol-Binding Proteins / Q000378:metabolism*; D054840:Retinol-Binding Proteins, Cellular; D014801:Vitamin A / Q000378:metabolism*
C033190:DNA-cellulose; D012177:Retinol-Binding Proteins; D054840:Retinol-Binding Proteins, Cellular; D014801:Vitamin A; D000255:Adenosine Triphosphate; D002482:Cellulose; D004247:DNA