Carcinogenicity testing of atrazine: preliminary report on a 13-month study on male Swiss albino mice treated by intraperitoneal administration.
A statistically significant increase (p less than 0.001) of lymphomas (4 of plasmacell type and two of histiocytic type) was found in a group of 30 Swiss albino mice which were given intraperitoneally 0.25 cc of a 2 ppm solution of atrazine for 13 times every third day to total administration of 0.26 mg of Atrazine/kg of body weight. Lymphomas arising in two groups of 50 controls was 0 and 1 respectively.
Donna
A
A
Department of Pathology, City Hospital, U.S.S.L., Alessandria, Italy.
Betta
P G
PG
Robutti
F
F
Bellingeri
D
D
D000818:Animals; D001280:Atrazine / Q000008:administration & dosage / Q000633:toxicity*; D007274:Injections, Intraperitoneal; D008223:Lymphoma / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests
D001280:Atrazine