title: Gm 3;5,13,14 and stated-admixture: independent estimates of admixture in American Indians.
abstract: Bernstein's formula for the estimation of the amount of admixture (m) in a hybrid population has been used frequently since its publication in 1931. While mathematically correct, it has not been shown to be correct in practice, because an independent estimate from a large sample has not been available. We have compared the estimate of m for Caucasian admixture derived by using Bernstein's formula with that estimated from stated-admixture (Sa) within a sample of 5,759 Native Americans. There was a linear relationship between the two variables (m = -.000275 + .714Sa; r = .976 for the grouped data, P = .0001).
authors.forename: R C
authors.initials: RC
authors.lastname: Williams
authors.forename: A G
authors.initials: AG
authors.lastname: Steinberg
authors.forename: W C
authors.initials: WC
authors.lastname: Knowler
authors.forename: D J
authors.initials: DJ
authors.lastname: Pettitt
mesh_terms: D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D007129:Immunoglobulin Gm Allotypes / Q000235:genetics*; D007198:Indians, North American; D014481:United States
chemical_list: D005819:Genetic Markers; D007129:Immunoglobulin Gm Allotypes