The value of case reports in human teratology.
Birth defects caused by human teratogens are an important and potentially preventable cause of perinatal morbidity and mortality. Case reports provide an initial suggestion that a specific agent may be a human teratogen and provide the basis for further study. This review discusses the importance of case reports in human teratology and provides guidance in evaluating new case reports.
Goldberg
J D
JD
Golbus
M S
MS
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology / Q000209:etiology; D000818:Animals; D000932:Antiemetics / Q000009:adverse effects; D004025:Dicyclomine; D004319:Doxylamine / Q000009:adverse effects; D004338:Drug Combinations / Q000009:adverse effects; D004917:Erythromycin / Q000009:adverse effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015474:Isotretinoin; D008499:Medical Records; D011247:Pregnancy; D011643:Publishing; D011736:Pyridoxine / Q000009:adverse effects; D013723:Teratogens; D013792:Thalidomide / Q000009:adverse effects; D014212:Tretinoin / Q000009:adverse effects; D014859:Warfarin / Q000009:adverse effects
D000932:Antiemetics; D004338:Drug Combinations; D013723:Teratogens; C004454:dicyclomine, doxylamine, pyridoxine drug combination; D004025:Dicyclomine; D013792:Thalidomide; D014212:Tretinoin; D014859:Warfarin; D004917:Erythromycin; D004319:Doxylamine; D015474:Isotretinoin; D011736:Pyridoxine