Temporary threshold shift induced by noise exposure and moderate salicylate intake.
Temporary threshold shift was examined in 10 voluntary subjects who were exposed on 5 occasions to noise only and on 5 additional occasions to noise after intake of 1 g acetylsalicylic acid (ASA). The results showed no evidence that moderate doses of ASA potentiate temporary threshold shift. Subjects tested before and 1 hour after intake of ASA showed hearing improvement after intake of ASA. This threshold shift was confirmed, by a control trial, to depend on a practice effect rather than on the ASA.
Lindgren
F
F
Axelsson
A
A
D000293:Adolescent; D000328:Adult; D001241:Aspirin / Q000494:pharmacology*; D001305:Auditory Fatigue / Q000187:drug effects*; D006801:Humans; D008297:Male; D009622:Noise / Q000009:adverse effects*
D001241:Aspirin