title: Acute lymphoblastic leukemia in a child with constitutional ring chromosome 21.
abstract: This report describes a case of acute lymphoblastic leukemia with non-B, non-T, common acute lymphocytic leukemia antigen-positive blasts in a 13-year-old child with constitutional ring chromosome #21. Because ring chromosome #21 is a rare chromosomal disorder, it is likely that the leukemia transformation is related to the chromosomal anomaly.
authors.forename: A M
authors.initials: AM
authors.lastname: Falchi
authors.forename: M G
authors.initials: MG
authors.lastname: Orofino
authors.forename: A L
authors.initials: AL
authors.lastname: Nucaro
authors.forename: S
authors.initials: S
authors.lastname: De Virgiliis
authors.forename: A
authors.initials: A
authors.lastname: Cao
mesh_terms: D000293:Adolescent; D002869:Chromosome Aberrations; D002891:Chromosomes, Human, Pair 21; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics*; D008297:Male; D010375:Pedigree; D012303:Ring Chromosomes
chemical_list: D005819:Genetic Markers