title: Electrophysiological and histological study of synaptic connections between lateral geniculate transplant and host visual cortex.
abstract: The lateral geniculate nucleus (LGN) of fetal Wistar rats was transplanted to the visual cortex (VC) of 33 neonatal Wistar rats. Histological examination showed transplanted cells in all the host brains. Intensively labeled cells were demonstrated in the transplant by labeling with true blue. Electrophysiological studies with brain slice preparations demonstrated that the transplanted LGN sent axons and made excitatory monosynaptic connections mainly in layer IV of the VC area 17. Corticogeniculate projections were also demonstrated in the transplanted LGN.
authors.affiliation: Department of Neurosurgery, Kyoto Prefectural University of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hamasaki
authors.forename: K
authors.initials: K
authors.lastname: Hirakawa
authors.forename: K
authors.initials: K
authors.lastname: Toyama
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D004594:Electrophysiology; D005333:Fetus; D005829:Geniculate Bodies / Q000033:anatomy & histology / Q000637:transplantation*; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000502:physiology; D014793:Visual Cortex / Q000033:anatomy & histology / Q000502:physiology*