SCC tumour marker and its relationship to clinical stage in squamous cervical cancer.
Serum from 103 patients with histologically proven squamous cell cervical carcinoma were analysed for the presence of tumour marker, SCC antigen. Although values ranged between 0.2-109.7 ng/ml the majority of cases (75%) fell below 7.9 ng/ml. There was no relationship between SCC antigen values and clinical stage. The high false negative rate (29%) of this marker in patients with proven disease would preclude its use as a diagnostic screen.
Henry
R J
RJ
Department of Obstetrics and Gynaecology, University of Sydney, Westmead Hospital, New South Wales.
Dodd
J K
JK
Tyler
J P
JP
Houghton
C R
CR
D000951:Antigens, Neoplasm / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D005260:Female; D006801:Humans; D011863:Radioimmunoassay; D015843:Serpins; D002583:Uterine Cervical Neoplasms / Q000276:immunology*
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D015843:Serpins; C051072:squamous cell carcinoma-related antigen; C036649:tumor antigen TA-4, human