title: Pubertal development in girls. Variability and interrelationships.
abstract: Concerns about somatic disturbances of pubertal development are most frequently due to the large variability in normal growth and development patterns which occur during this age period. This article provides data on the normal variation of the following aspects of pubertal development: secondary sex characteristics, height growth, and menstrual cycles. In addition, clinically relevant interrelationships between the appearance of pubertal signs, height growth and bone age are discussed. The data presented are based on the First Zurich Longitudinal Study.
authors.affiliation: Universitäts-Kinderspital Zürich, Switzerland.
authors.forename: R H
authors.initials: RH
authors.lastname: Largo
authors.forename: A
authors.initials: A
authors.lastname: Prader
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001827:Body Height; D001846:Bone Development; D002648:Child; D005260:Female; D006128:Growth; D006801:Humans; D008137:Longitudinal Studies; D008597:Menstrual Cycle; D011627:Puberty / Q000502:physiology*; D012016:Reference Values; D012494:Sampling Studies; D012727:Sex Characteristics; D013557:Switzerland