Neutrophils with ring-shaped nuclei in chronic neutrophilic leukemia.
A significant incidence of neutrophils with ring-shaped nuclei was observed in all of four patients with chronic neutrophilic leukemia. The present data may give further support for the view that chronic neutrophilic leukemia is not a reactive disorder but a rare form of myeloproliferative disorder. It seems possible that this phenomenon can be used as a marker for abnormal granulopoiesis in human diseases.
Kanoh
T
T
Saigo
K
K
Yamagishi
M
M
D002467:Cell Nucleus / Q000648:ultrastructure*; D002908:Chronic Disease; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D009504:Neutrophils / Q000648:ultrastructure*