A new interstitial deletion of chromosome No. 4 del(4) (q22::q25).
A female child is described with multiple anomalies including epicanthus, frontal bossing, short sternum, polydactyly, cleft of the larynx, renal cysts, and unusual dermatoglyphics. She died aged 3 months and was found to have a unique de novo deletion of chromosome No. 4 (q22-q25). This case is compared with other long arm deletions of 4q and reference made to assignment of genetic markers to chromosome No. 4.
Butler
L J
LJ
Palmer
A V
AV
Spencer
T
T
Tabios-Broadway
R
R
Wall
W J
WJ
D000015:Abnormalities, Multiple / Q000235:genetics*; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002894:Chromosomes, Human, Pair 4; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007231:Infant, Newborn; D012886:Skull / Q000002:abnormalities; D013249:Sternum / Q000002:abnormalities
D005819:Genetic Markers