title: Approximate computation of probability functions for pedigree analysis.
abstract: Approximation by factorization of R functions is considered as a way of making the peeling method for calculation of probability functions more efficient and applicable to larger and more complex pedigrees. We show that, in some situations, the method is not approximate but a simplified way of calculating the true probability functions. The entropy function is used for a measure of the quality of factorization. The method is illustrated by an analysis of the origin of the B allele in the ABO blood type system on Tristan da Cunha.
authors.affiliation: Department of Statistics and Computational Mathematics, Brownlow Hill.
authors.forename: A
authors.initials: A
authors.lastname: Thomas
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics*; D000483:Alleles; D001266:Atlantic Islands; D001699:Biometry; D006801:Humans; D008957:Models, Genetic; D010375:Pedigree; D011336:Probability
chemical_list: D000017:ABO Blood-Group System