title: Management of prolonged pregnancy: induction of labor versus antepartum fetal testing.
abstract: Three hundred two low-risk obstetric patients with an unfavorable cervical examination and well-established gestational age of at least 287 days were randomly selected for management by either antepartum fetal testing or prostaglandin gel cervical ripening followed by aggressive induction of labor and delivery. The patients managed by induction of labor had a lower incidence of meconium-stained amniotic fluid, meconium aspiration, low Apgar scores, postmaturity syndrome, fetal distress, and cesarean delivery than did patients managed with antepartum fetal testing. Our data suggest that prostaglandin gel cervical ripening and induction of labor and delivery by 42 weeks' gestation may be the most appropriate management for patients with well-established gestational age and an unfavorable cervical examination.
authors.forename: D C
authors.initials: DC
authors.lastname: Dyson
authors.forename: P D
authors.initials: PD
authors.lastname: Miller
authors.forename: M A
authors.initials: MA
authors.lastname: Armstrong
mesh_terms: D015232:Dinoprostone; D005260:Female; D005313:Fetal Death / Q000517:prevention & control; D005323:Fetal Monitoring / Q000379:methods*; D005782:Gels; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced / Q000379:methods*; D007744:Obstetric Labor Complications / Q000517:prevention & control; D011247:Pregnancy; D011273:Pregnancy, Prolonged / Q000187:drug effects; D011458:Prostaglandins E / Q000627:therapeutic use; D011897:Random Allocation; D012306:Risk
chemical_list: D005782:Gels; D011458:Prostaglandins E; D015232:Dinoprostone