title: Autoradiographic study of cell proliferation in acanthotic buccal epithelium of zinc-deficient rabbits.
abstract: A zinc-deficient diet for 3 weeks led to acanthotic, hyperparakeratotic buccal epithelium in which the labelling and mitotic indices were increased. The total cell-cycle time was greatly reduced due to reduction in the transit time of the GI phase and, to a lesser extent, of the S and G2 phases. The results cannot be explained by decreased activity of DNA synthesis. They may be due to loss of growth inhibition in oral epithelium.
authors.forename: S Y
authors.initials: SY
authors.lastname: Chen
mesh_terms: D000818:Animals; D001345:Autoradiography; D001835:Body Weight; D002453:Cell Cycle; D002455:Cell Division; D002610:Cheek; D008297:Male; D008940:Mitotic Index; D009061:Mouth Mucosa / Q000166:cytology*; D011817:Rabbits; D015032:Zinc / Q000172:deficiency*
chemical_list: D015032:Zinc