Antiprotozoal activity of diospyrin towards Leishmania donovani promastigotes in vitro.
Diospyrin, a bis-naphthoquinone derivative, isolated from a plant, known for its antitumour properties against Ehrlich ascites carcinoma in Swiss A mice, exhibits antiprotozoal activity towards L. donovani promastigotes in culture.
Hazra
B
B
Department of Pharmacy, Jadavpur University, Calcutta, India.
Saha
A K
AK
Ray
R
R
Roy
D K
DK
Sur
P
P
Banerjee
A
A
D000818:Animals; D004305:Dose-Response Relationship, Drug; D007893:Leishmania donovani / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D009285:Naphthoquinones / Q000494:pharmacology*; D010101:Oxygen Consumption; D013997:Time Factors
D009285:Naphthoquinones; C043546:diospyrin