title: Multiple forms of aryl acylamidase in regional tissues of developing rat brain.
abstract: The specific activities of two forms of aryl acylamidase (AAA) were examined in 7 regions of the developing rat brain, plus the remainder of the brain and the whole brain. AAA-1 activity peaked at 15 days old in all brain regions studied except the whole brain where it peaked at 22 days of age. AAA-2 activity peaked between 15 and 29 days old in most brain regions studied except corpus striatum and hippocampus where the AAA-2 activity peaked before 15 days old. In all areas and at all time periods, with the exception of CS after 15 days of age, AAA-2 activity was much higher than that of AAA-1. The developmental pattern of AAA-1 is generally the same in the different brain regions while that of AAA-2 shows more regional specificity. These results indicate that neither AAA-1 nor AAA-2 may be associated with amine N-acetyltransferase in the brain which has an entirely different developmental pattern.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston 77550.
authors.forename: L L
authors.initials: LL
authors.lastname: Hsu
mesh_terms: D000375:Aging / Q000378:metabolism*; D000581:Amidohydrolases / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology* / Q000254:growth & development; D007527:Isoenzymes / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D007527:Isoenzymes; D000581:Amidohydrolases; C019732:aryl acylamidase