title: [Ofloxacin in the conservative therapy of acute and chronic otitis media--a preliminary clinical report of experiences].
abstract: After ascertaining the bacterial spectrum in 105 patients with Otitis media acutissima, Otitis media chronica mesotympanalis and Otitis media chronica epitympanalis, the efficacy of oral therapy with ofloxacin in five patients from each of these groups was assessed. The results are comparable with those following conventional local and intravenous antibiotic therapy. On the basis of these preliminary results, ofloxacin can be considered as a highly efficient oral substance which is effective against Staphylococcus aureus and Pseudomonas aeruginosa, two important pathogens in inflammatory ear infections.
authors.forename: T
authors.initials: T
authors.lastname: Lenarz
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy*; D002908:Chronic Disease; D006801:Humans; D015242:Ofloxacin; D010033:Otitis Media / Q000188:drug therapy*; D010034:Otitis Media with Effusion / Q000188:drug therapy; D010078:Oxazines / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D010078:Oxazines; D015242:Ofloxacin
vernacular_title: Ofloxacin in der konservativen Therapie der akuten und chronischen Otitis media--Ein vorläufiger klinischer Erfahrungsbericht.