Endogenous sex hormones, prolactin, and mammographic features of breast tissue in premenopausal women.
The relationship between levels of certain endogenous hormones and the mammographic features of breast tissue was evaluated in 110 premenopausal women who were referred to hospital-based radiology units for a routine xeromammogram. This analysis was based on specimens collected during the luteal phase of the menstrual cycle. Plasma 17 beta-estradiol, progesterone, and prolactin were measured, as well as urine estrone, estradiol, estriol, and pregnanediol. The main xeromammographic features of the breast assessed were Wolfe's parenchymal pattern and the percentages of the breast showing nodular densities and homogeneous density. In these data, endogenous hormones were not strongly associated with mammographic features of breast tissue. However, women with the N1 and P1 parenchymal patterns had somewhat higher levels of estrogens and prolactin and somewhat lower levels of progesterone than women with the P2 and DY patterns.
Meyer
F
F
Brisson
J
J
Morrison
A S
AS
Brown
J B
JB
D000328:Adult; D001943:Breast Neoplasms / Q000032:analysis* / Q000000981:diagnostic imaging; D005260:Female; D012739:Gonadal Steroid Hormones / Q000032:analysis*; D006801:Humans; D008327:Mammography; D008593:Menopause; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*
D012739:Gonadal Steroid Hormones; D011388:Prolactin