title: Cloning and expression of human apolipoprotein D cDNA.
abstract: The amino acid sequence of human apolipoprotein D, a component of high density lipoprotein, has been obtained from the cloned cDNA sequence. The 169-amino acid protein has no marked similarity to other apolipoprotein sequences, but has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2u-globulin protein superfamily. Apolipoprotein D mRNA has been detected in human liver, intestine, pancreas, kidney, placenta, adrenal, spleen, and fetal brain tissue. Tissue culture cells transfected with the cloned cDNA secrete material that reacts with anti-apoD antibodies.
authors.forename: D
authors.initials: D
authors.lastname: Drayna
authors.forename: C
authors.initials: C
authors.lastname: Fielding
authors.forename: J
authors.initials: J
authors.lastname: McLean
authors.forename: B
authors.initials: B
authors.lastname: Baer
authors.forename: G
authors.initials: G
authors.lastname: Castro
authors.forename: E
authors.initials: E
authors.lastname: Chen
authors.forename: L
authors.initials: L
authors.lastname: Comstock
authors.forename: W
authors.initials: W
authors.lastname: Henzel
authors.forename: W
authors.initials: W
authors.lastname: Kohr
authors.forename: L
authors.initials: L
authors.lastname: Rhee
mesh_terms: D000595:Amino Acid Sequence; D001053:Apolipoproteins / Q000097:blood / Q000235:genetics*; D053399:Apolipoproteins D; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000378:metabolism*; D006801:Humans; D008970:Molecular Weight; D014158:Transcription, Genetic
chemical_list: D001053:Apolipoproteins; D053399:Apolipoproteins D; D004247:DNA