Marker ring chromosome--a new cytogenetic abnormality characterizing lipogenic tumors?
We have analyzed three intramuscular lipomas, two atypical and one with ordinary benign histology, as part of a systematic study of the karyotypic characteristics of mesenchymal tumors. A large ring chromosome of uncertain origin, but possibly representing a rearranged chromosome #3, was found in all three tumors. Previous reports on the chromosome banding pattern in lipogenic neoplasms are restricted to only three cases, all liposarcomas. In one of these, a well differentiated liposarcoma, a ring chromosome was described that was remarkably similar in morphology to the aberration reported here. We conclude that this ring chromosome may constitute a characteristic cytogenetic marker for lipogenic tumors.
Heim
S
S
Mandahl
N
N
Kristoffersson
U
U
Mitelman
F
F
Rööser
B
B
Rydholm
A
A
Willén
H
H
D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002893:Chromosomes, Human, Pair 3; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008067:Lipoma / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D012303:Ring Chromosomes; D013848:Thigh
D005819:Genetic Markers