[Antiviral action of sodium selenite and its combination with remantadine].
The combined effect of sodium selenite and remantadine on influenza A virus reproduction in vitro and in vivo is described. The effect of sodium selenite on influenza virus transcriptase was studied. Inoculation of remantadine in combination with nontoxic concentrations of sodium selenite was found to be a promising combination for inhibition of experimental influenza infection.
Abdullaev
I I
II
Sycheva
I V
IV
Lazymova
Z A
ZA
Veselovskaia
T V
TV
Abdullaev
F I
FI
D000218:Adamantane / Q000031:analogs & derivatives*; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002642:Chick Embryo; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D009980:Influenza A virus / Q000187:drug effects / Q000502:physiology; D051379:Mice; D008826:Microbial Sensitivity Tests / Q000379:methods; D009976:Orthomyxoviridae Infections / Q000188:drug therapy; D012254:Ribavirin / Q000494:pharmacology / Q000627:therapeutic use; D012299:Rimantadine / Q000494:pharmacology* / Q000627:therapeutic use; D020887:Selenious Acid; D012643:Selenium / Q000494:pharmacology* / Q000627:therapeutic use; D014776:Virus Cultivation; D014779:Virus Replication / Q000187:drug effects
D000998:Antiviral Agents; D012299:Rimantadine; D012254:Ribavirin; D020887:Selenious Acid; D012643:Selenium; D000218:Adamantane
Izuchenie protivovirusnogo deĭstviia selenita natriia i ego kombinatsii s remantadinom.