[A case of adult Still's disease with cardial symptoms of remittent high fever and arthralgia for more than six months].
A 46-year-old woman was admitted to our hospital because of fever of unknown origin. Her fever continued with a daily rise to around 38 degrees C to 40 degrees C for more than six months, occasionally accompanied by polyarthralgia, erythematous rash and cervical lymphadenopathy. The erythrocyte sedimentation rate was 75 mm per hour and CRP was over 6+. The white-cell count was 15,100 with 21 percent band forms and the alpha 2-globulin was 18.8 percent of total protein. The tests for autoantibodies were negative. Clinical course and laboratory findings in this case were most compatible with adult Still's disease. A radionucleotide bone scan with 99mTc showed a greatly increased uptake of the radionucleotide at the large joints of the whole body, and a gallium scan also revealed accumulation of the radionucleotide at the bone marrow of the sternum. These findings were recognized during high fever and disappeared when the body temperature returned to normal. These examinations might be useful for investigating the active site of inflammation and for studying the pathogenesis of adult Still's disease.
Okazaki
M
M
Tabaru
A
A
Yagita
M
M
Morita
Y
Y
Taoka
Y
Y
D001171:Arthritis, Juvenile / Q000150:complications / Q000175:diagnosis*; D001842:Bone and Bones / Q000000981:diagnostic imaging; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology*; D005710:Gallium Radioisotopes; D006801:Humans; D007596:Joints; D008875:Middle Aged; D010146:Pain / Q000209:etiology*; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate
D005710:Gallium Radioisotopes; D013669:Technetium Tc 99m Medronate