title: [Study of the phytoiatric antifungal activity of derivatives of 2- and 4-aminophenylthioacetonitrile and ethyl 4-aminophenylthioacetate].
abstract: Some N-acyl and N-carbamoyl-derivatives of 2-, of 4-amino-phenylthioacetonitrile and of ethyl 4-aminophenylthioacetate, and also some N-thiocarbamoylderivatives of the latter were prepared in order to test their antimycotic activity against representative plant parasites. The substances, (I-XXVI), mostly unknown, were subjected to in vitro and in vivo tests (in preventive phase). Some of the compounds studied, especially the 2-aminophenylthioacetonitrilic derivatives, showed in the in vivo tests interesting activity and good specificy against P. viticola.
authors.affiliation: Dipartimento di Chimica Farmaceutica, Università degli Studi di Pavia.
authors.forename: M L
authors.initials: ML
authors.lastname: Carmellino
authors.forename: G
authors.initials: G
authors.lastname: Massolini
mesh_terms: D000085:Acetates / Q000138:chemical synthesis* / Q000494:pharmacology; D000097:Acetonitriles / Q000138:chemical synthesis* / Q000494:pharmacology; D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D005658:Fungi / Q000187:drug effects; D008826:Microbial Sensitivity Tests
chemical_list: D000085:Acetates; D000097:Acetonitriles; D000814:Aniline Compounds; D000935:Antifungal Agents
vernacular_title: Studio dell'attivita' antifungina fitoiatrica di derivati del 2- e del 4-aminofeniltioacetonitrile e del 4-aminofeniltioacetato d'etile.