Estimation of inbreeding parameters in stratified populations.
A clarification is given of the differences in approaches to the estimation of F-statistics of Nei & Chesser [Ann. Hum. Genet. (1983) 47, 253-259] and Cockerham [Genetics (1973) 74, 679-700]. The principal difference is that Nei & Chesser define quantities with respect to fixed extant populations, while Cockerham allows for evolutionary variation between populations. Weighted and unweighted analyses are compared, and a numerical example given.
Cockerham
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CC
Department of Statistics, North Carolina State University, Raleigh 27695-8203.
Weir
B S
BS
D000483:Alleles; D000704:Analysis of Variance; D003241:Consanguinity; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D013223:Statistics as Topic