title: [Complete neurological recovery after major neonatal acidosis].
abstract: After a severe fetal asphyxia, an hypotrophic (PN: 2,500 g) full-term newborn had a very poor Apgar score (1 after 1 min) and intensive resuscitation was necessary. The first arterial blood gas analysis at 1 h of life showed a profound metabolic acidosis (pH: 6.7; base defect: -30) and refractory hypoxemia (PaO2: 11 mmHg; FiO2 = 1). In a first time, the outcome was favourable after the correction of acidosis and treatment with tolazoline of a persistent fetal circulation. The depressed cerebral function symptoms disappeared within a few days; a grade I subependymal haemorrhage disappeared also rapidly. At 22 months of age, the infant had no significant developmental abnormality.
authors.affiliation: Service de réanimation et de maladies infectieuses, CHRU, Caen, France.
authors.forename: C
authors.initials: C
authors.lastname: Perrin
mesh_terms: D000138:Acidosis / Q000151:congenital* / Q000209:etiology / Q000628:therapy; D001238:Asphyxia Neonatorum / Q000150:complications; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D007231:Infant, Newborn; D011379:Prognosis; D012151:Resuscitation
vernacular_title: Récupération neurologique complète après une acidose néo-natale majeure.