title: Trisomy 4: an entity within acute nonlymphocytic leukemia.
abstract: Trisomy 4 is a newly recognized primary chromosome change in leukemia. Five cases of acute nonlymphocytic leukemia (ANLL) are described from the United States and France. As in cases from Belgium, the only chromosome abnormality detected in the leukemic cells was trisomy 4. This was associated preferentially with ANLL of the M4 type (by FAB classification): acute myelomonocytic leukemia.
authors.forename: A A
authors.initials: AA
authors.lastname: Sandberg
authors.forename: R
authors.initials: R
authors.lastname: Morgan
authors.forename: S N
authors.initials: SN
authors.lastname: Sait
authors.forename: R
authors.initials: R
authors.lastname: Berger
authors.forename: G
authors.initials: G
authors.lastname: Flandrin
authors.forename: S
authors.initials: S
authors.lastname: Schrier
authors.forename: F
authors.initials: F
authors.lastname: Hecht
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002894:Chromosomes, Human, Pair 4; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007938:Leukemia / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics; D008297:Male; D008875:Middle Aged; D014314:Trisomy
chemical_list: D005819:Genetic Markers