title: [Effect of Neowetadina and Polyvaccinum on serum levels of immunoglobulins and total proteins in calves during the industrial fattening process].
abstract: The usefulness of nonspecific stimulating preparations-Neowetadina (Biowet) and Poliwakcyna (Polfa) for stimulation of the serum level of immunoglobulins of the classes IgG, IgA and IgM and total protein was determined in calves of the black and white breed at the age of 9-10 weeks (average body weight 75-80 kg) over 8 weeks from the onset of industrial fattening in technological groups. The stimulants were given in single intramuscular injections at the following doses: 0.08 and 0.4 ml of Neowetadina per 1 kg of body weight, 0.4 ml of Poliwakcyna forte per 1 kg of body weight. The level of the particular classes of immunoglobulins in the calf sera was determined by radial immunodiffusion according to Mancini et al., modified by Fahey and McKelvey, and that of total protein by the biuret method. The serum of the IgG class immunoglobulins increased statistically significantly (P less than or equal to 0.05), starting from the 4th week after the administration of the preparations and reached its maximal value in the 5th week. However, the serum level of IgA increased in the 8th week of observation. Poliwakcyna and Neowetadina effected only slightly the increase of the serum level of IgM immunoglobulins. The preparations also stimulated the increase of total protein level in the blood serum of the calves.
authors.affiliation: Instytut Chorób Zakaźnych i Inwazyjnych Akademii Rolniczej, Lublin.
authors.forename: J
authors.initials: J
authors.lastname: Rzedzicki
authors.forename: Z
authors.initials: Z
authors.lastname: Gliński
authors.forename: Z
authors.initials: Z
authors.lastname: Kaźmir
authors.forename: J
authors.initials: J
authors.lastname: Mikucki
mesh_terms: D000276:Adjuvants, Immunologic; D000822:Animal Husbandry; D000818:Animals; D001426:Bacterial Proteins / Q000494:pharmacology*; D001428:Bacterial Vaccines / Q000494:pharmacology*; D001798:Blood Proteins / Q000032:analysis*; D002417:Cattle / Q000276:immunology*; D007113:Immunity, Innate; D007136:Immunoglobulins / Q000032:analysis*
chemical_list: D000276:Adjuvants, Immunologic; D001426:Bacterial Proteins; D001428:Bacterial Vaccines; D001798:Blood Proteins; D007136:Immunoglobulins
vernacular_title: Wpływ Neowetadiny i Poliwakcyny na poziom immunoglobulin oraz białka całkowitego w surowicy krwi u cielat w tuczu przemysłowym.