[Various characteristics of proteins from HeLa cella specifically binding to the human ALU sequence].
Two proteins with molecular weights of 40 and 80 kDa which are able to bind human Alu-repeat in a sequence-specific manner were found in HeLa nuclear extracts. The proteins were partially purified by column chromatography on DEAE-cellulose, phosphocellulose and FPLC MonoQ sorbent. One of the Alu-binding proteins (ABP2 with m. w. of 80 kDa) was found to bind the sequence within the Alu-repeat that has a homology with the T-antigen binding site of SV40, suggesting that ABP2 is the cellular analog of SV40 T-antigen.
Perelygina
L M
LM
Tomilin
N V
NV
Podgornaia
O I
OI
D002848:Chromatography, DEAE-Cellulose; D004268:DNA-Binding Proteins / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D006367:HeLa Cells; D006801:Humans; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
D004268:DNA-Binding Proteins
Nekotorye kharakteristiki belkov iz kletok HeLa, spetsificheski sviazyvaiushchikh ALU-posledovatel'nost' cheloveka.