title: Experimentally induced lactic acidosis in the goat.
abstract: Lactic acidosis was produced experimentally twice in each of 4 adult, female goats, by giving sucrose orally at the rate of 18 g/kg bodyweight. Changes in pH, osmolality, lactic acid concentration, and other constituents in ruminal fluid, plasma and blood were monitored over a period of 48 h. Also changes in urinary pH and sediment were examined. To ameliorate the metabolic disturbance, calcium hydroxide and bicarbonate treatment was employed after the 24 h samples had been collected and their acid-base status determined. A feature of the disturbance in the goats was that a metabolic alkalosis preceded the onset of lactic acidosis.
authors.affiliation: Department of Veterinary Medicine, University of Queensland, St Lucia.
authors.forename: G R
authors.initials: GR
authors.lastname: Cao
authors.forename: P B
authors.initials: PB
authors.lastname: English
authors.forename: L J
authors.initials: LJ
authors.lastname: Filippich
authors.forename: S
authors.initials: S
authors.lastname: Inglis
mesh_terms: D000140:Acidosis, Lactic / Q000097:blood / Q000378:metabolism / Q000652:urine / Q000662:veterinary*; D000818:Animals; D005260:Female; D006041:Goats / Q000378:metabolism*; D012417:Rumen / Q000378:metabolism