In vitro investigations with selective adsorbents for IgE and IgM.
In vitro studies were carried out with IM-T. This adsorbent consists of polyvinyl alcohol joined with tryptophan side chains and was delivered by ASAHI Medical Co., Ltd., Tokyo/Japan. It was found that IM-T binds immunoglobulins G and M and also immune complexes only moderately but IgE was adsorbed in remarkable amounts. A clear dose-dependent was adsorbed in remarkable amounts. A clear dose-dependent manner of the IgE adsorption could be stated. Kinetic studies revealed that the binding was only slow and gradual.
Behm
E
E
Department of Internal Medicine, Wilhelm-Pieck-University, Rostock, GDR.
Kuroda
T
T
Yamawaki
N
N
Tsuda
N
N
Loth
F
F
Schwachula
G
G
Sabrowski
E
E
Falkenhagen
D
D
Klinkmann
H
H
D000818:Animals; D000936:Antigen-Antibody Complex; D006801:Humans; D007073:Immunoglobulin E / Q000302:isolation & purification*; D007075:Immunoglobulin M / Q000302:isolation & purification*; D007164:Immunosorbents; D066298:In Vitro Techniques
D000936:Antigen-Antibody Complex; D007075:Immunoglobulin M; D007164:Immunosorbents; D007073:Immunoglobulin E