title: Antigenic properties of fresh and lyophylised human dura mater.
abstract: The action of human fresh and lyophylised human dura mater on rat, rabbit and human serum complement has been analyzed with the aim of confirming and comparing the species-specific antigenicity of both substances. The results demonstrate that both fresh and lyophylised human dura mater induce a complement consumption on rat and rabbit serum. The phenomenon is related to the species-specific antigenic activity of the tissue, and it is only partially decreased by the lyophylisation procedure. The residual antigenic activity, however, doesn't limit the use of this material as a graft for dural defects repairs in humans.
authors.affiliation: Chair of Neurosurgery of the University, Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Occhiogrosso
authors.forename: A
authors.initials: A
authors.lastname: De Tommasi
authors.forename: G
authors.initials: G
authors.lastname: Vailati
mesh_terms: D000818:Animals; D003165:Complement System Proteins / Q000276:immunology*; D004388:Dura Mater / Q000276:immunology*; D005612:Freeze Drying; D006801:Humans; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
chemical_list: D003165:Complement System Proteins