Effect of lipid-free milk on prostaglandin synthesis and lipid esterification in the young rabbit aorta.
The effect of lipid-free human milk on prostaglandin synthesis and lipid esterification by [14C]-arachidonic acid was examined in one week-old rabbit aortas, in vitro. In the presence of albumin, lipid-free milk increased arachidonic acid incorporation into aortic phospholipids, cholesterol esters and triglycerides but not into mono- and diglycerides. Lipid-free milk also increased the conversion of arachidonic acid into aortic 6-keto-PGF1 alpha, but not into PGF2 alpha or PGE2.
Bydlowski
S P
SP
Departamento de Ciências Fistológicas, Faculdade de Ciências Médicas da Santa Casa de São Paulo, Brasil.
D000818:Animals; D001011:Aorta / Q000378:metabolism*; D001095:Arachidonic Acids / Q000378:metabolism*; D004951:Esterification; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D050356:Lipid Metabolism; D008297:Male; D008895:Milk, Human; D011453:Prostaglandins / Q000096:biosynthesis*; D011817:Rabbits
D001095:Arachidonic Acids; D011453:Prostaglandins