title: The effect of chemotherapy on osteosarcoma of the extremities as apparent from conventional roentgenograms.
abstract: The introduction of chemotherapy has greatly changed the treatment of osteosarcoma. During the preoperative phase the tumor response to chemotherapy can be assessed in various ways. This paper discusses the clinical, histological and radiological response to preoperative chemotherapy in three patients. Changes in conventional roentgenograms following chemotherapy can reflect the effect of chemotherapy on the primary tumor. This can be important in planning further chemotherapy or surgery.
authors.forename: G J
authors.initials: GJ
authors.lastname: den Heeten
authors.forename: C J
authors.initials: CJ
authors.lastname: Thijn
authors.forename: W A
authors.initials: WA
authors.lastname: Kamps
authors.forename: H
authors.initials: H
authors.lastname: Schraffordt Koops
authors.forename: J W
authors.initials: JW
authors.lastname: Oosterhuis
authors.forename: J
authors.initials: J
authors.lastname: Oldhoff
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011300:Preoperative Care; D011859:Radiography