title: DNA sequence of the coding region of the HLA-B44 gene.
abstract: An HLA-B44 cDNA clone was identified in a cDNA library constructed from an HLA-B44 homozygous cell line. The DNA sequence was determined and was found to contain the complete coding sequence but for (probably) the three N-terminal codons. Comparisons of the derived amino acid sequence with other HLA-A and -B locus amino acid sequences revealed four HLA-B44-specific substitutions including a new polymorphic site. Regions of strong sequence conservation for HLA-B-locus products were found at the nucleotide and amino acid levels.
authors.forename: A H
authors.initials: AH
authors.lastname: Kottmann
authors.forename: G H
authors.initials: GH
authors.lastname: Seemann
authors.forename: H D
authors.initials: HD
authors.lastname: Guessow
authors.forename: M H
authors.initials: MH
authors.lastname: Roos
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D004247:DNA / Q000032:analysis; D005796:Genes; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D059948:HLA-B44 Antigen; D006801:Humans; D011110:Polymorphism, Genetic
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D059948:HLA-B44 Antigen; D004247:DNA