Chronic neutrophilic leukemia: description of a new case with karyotypic abnormalities.
A further case of chronic neutrophilic leukemia (CNL) is reported. On karyotype analysis of the bone marrow aspirate, all of the examined cells showed trisomy of chromosome 9 and partial deletion of the long arms of chromosome 20. This anomaly has never before been reported in CNL, and it could be directly associated to the disease.
Di Donato
C
C
Croci
G
G
Lazzari
S
S
Scarduelli
L
L
Vignoli
R
R
Buia
M
M
Tramaloni
C
C
Maccari
S
S
Plancher
A C
AC
D000368:Aged; D001853:Bone Marrow / Q000648:ultrastructure; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D002903:Chromosomes, Human, 19-20; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000235:genetics* / Q000473:pathology; D008297:Male; D009504:Neutrophils; D014314:Trisomy