title: Histocompatibility antigens (HLA-A, B) and ulcerative colitis in a Greek population.
abstract: Histocompatibility antigens (HLA-A, B) have been studied in 70 patients with ulcerative colitis of Greek origin. An increased frequency of HLA-A11, B7 and B13 (RR 2.1, 2.0 and 4.5, respectively) and a decreased frequency of HLA-B14 (RR 0.2) were found. Severe course of the disease was associated mainly with HLA-B13 (RR 5.5) whereas extensive spread of the colitis was associated with HLA-A11 and B7 (RR 2.6 and 3.2). Late onset of the disease (greater than 30 years) was characterized by increased frequency of HLA-A11, B7 and B13.
authors.forename: C
authors.initials: C
authors.lastname: Papasteriades
authors.forename: C
authors.initials: C
authors.lastname: Spiliadis
authors.forename: A
authors.initials: A
authors.lastname: Emmanouilidis
authors.forename: C
authors.initials: C
authors.lastname: Papadimitriou
authors.forename: J
authors.initials: J
authors.lastname: Economidou
authors.forename: O
authors.initials: O
authors.lastname: Manousos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000235:genetics*; D004198:Disease Susceptibility; D005260:Female; D006115:Greece; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens