Plasma fibronectin in hemoblastosis.
Fibronectin (FN) is a glycoprotein whose plasma concentrations are reduced in many pathological conditions. In patients with hemoblastosis plasma FN was correlated with some clinical and biological parameters (stage of the disease, hepatosplenomegaly, infections and DIC), in order to assess its value as a tumor marker. The results suggest a poor relationship between FN levels and the course of the disease. However, the behaviour of the protein in relation with treatment was dynamic.
Curci
G
G
Cattedra di Terapia Medica Sistematica, University of Modena, Italy.
Frassoldati
A
A
Zioni
F
F
Zaniol
P
P
Piccinini
L
L
D014408:Biomarkers, Tumor / Q000032:analysis*; D005353:Fibronectins / Q000032:analysis*; D006529:Hepatomegaly / Q000150:complications; D006801:Humans; D007160:Immunoproliferative Disorders / Q000097:blood* / Q000150:complications; D007239:Infections / Q000150:complications; D007938:Leukemia / Q000097:blood* / Q000150:complications; D009196:Myeloproliferative Disorders / Q000097:blood* / Q000150:complications; D011379:Prognosis; D013163:Splenomegaly / Q000150:complications
D014408:Biomarkers, Tumor; D005353:Fibronectins