Unusual vascular malformation of the kidney in both twins of a monozygotic pair: short case report.
A case of double bilateral renal vessels in both twins of a MZ pair is reported for the first time. Even in non-twins, the anomalies reported so far involved the inferior polar arteries in agreement with the embryological development. The two male twins, examined at the age of 14 years, had simultaneously developed a marked hypertension at the age of 7 years. Zygosity was determined by blood group and HLA analysis and various clinical tests were carried out to diagnose the condition. It is suggested that the anomaly is the result of a genetically induced early block in embryonic development.
Mastroberardino
G
G
Fourth Chair of Clinical Medicine, School of Medicine, First University of Rome, Italy.
Sciarra
A
A
Gualtieri
R
R
Di Fusco
C
C
Grammatico
P
P
Del Porto
G
G
D000293:Adolescent; D004200:Diseases in Twins; D006801:Humans; D006973:Hypertension / Q000235:genetics; D008297:Male; D012077:Renal Artery / Q000002:abnormalities*; D014427:Twins; D014430:Twins, Monozygotic