[Structure of poly(dA).poly(dT) from data of x-ray diffraction, energy calculations and nuclear magnetic resonance].
The results of X-ray diffraction studies of poly(dA).poly(dT) have been compared with the results of energy optimization and with the NMR data in solution. Slight refinement of the X-ray and energetically optimal models leads to a very good quantitative agreement with the NMR data, that suggests similarity of the poly(dA).poly(dT) structure in a condensed state and in solution. One of the features distinguishing these models from the classic B form is a narrowed minor groove of the double helix. The anomalous properties of DNA with this sequence can be related specific organization of the water molecules near the polynucleotide.
Lipanov
A A
AA
Skuratovskiĭ
I Ia
IIa
Poltev
V I
VI
Golovinskaia
A G
AG
Chuprina
V P
VP
D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011067:Poly dA-dT / Q000032:analysis*; D011089:Polydeoxyribonucleotides / Q000032:analysis*; D014961:X-Ray Diffraction
D011089:Polydeoxyribonucleotides; D011067:Poly dA-dT
Struktura poli(dA).poli(dT) po dannym rentgenovskoĭ difraktsii, énergeticheskikh rashetov i iadernogo magnitnogo rezonansa.