[Effectiveness of a combined live mumps-measles vaccine].
The reactogenic and areactogenic properties of a live combined mumps-measles vaccine (MMV) prepared in primary cultures of Japanese quail embryo cells from attenuated strains of mumps (L-3) and measles (L-16) viruses were under study. The observations involved 648 infants varying in ages from 1 to 3 years, seronegative to measles and mumps viruses, without the history of the disease and vaccinations against these infections or contraindications to vaccinations. The infants were vaccinated with 5 batches of MMV with different portions of the mumps and measles components. The vaccinees and controls (placebo injections) were observed for 30 days postvaccination. The live MMV was shown to be a safe, well tolerated preparation with low reactogenicity and a high antigenic activity.
Unanov
S S
SS
Korzh
Iu N
IuN
Dorofeev
V M
VM
Iuminova
N V
NV
Myshliaeva
L A
LA
D000914:Antibodies, Viral / Q000032:analysis; D002675:Child, Preschool; D004306:Dose-Response Relationship, Immunologic; D004338:Drug Combinations; D004341:Drug Evaluation; D006801:Humans; D007223:Infant; D008458:Measles Vaccine / Q000009:adverse effects / Q000276:immunology*; D008459:Measles virus / Q000276:immunology; D009108:Mumps Vaccine / Q000009:adverse effects / Q000276:immunology*; D009109:Mumps virus / Q000276:immunology; D013997:Time Factors
D000914:Antibodies, Viral; D004338:Drug Combinations; D008458:Measles Vaccine; D009108:Mumps Vaccine
Issledovanie éffektivnosti zhivoĭ assotsiirovannoĭ parotitno-korevoĭ vaktsiny.