title: [Monoblastic (M5a) form of relapse in acute myeloblastic (M2) leukemia with t(8;21)].
abstract: An exceptional case of acute myeloblastic leukemia (M2) with t(8;21) relapsed as an acute monoblastic leukemia (M5). At that time only a minority of metaphases exhibited a t(8;21) and/or abnormality of chromosome No 11 long arm whereas various other chromosomal changes were present. The existence of a relapse of M2 with t(8;21) as M5 is discussed in relation to the commitment of the cells which became leukemic, and to the possibility of a second leukemia.
authors.forename: M T
authors.initials: MT
authors.lastname: Daniel
authors.forename: A
authors.initials: A
authors.lastname: Bernheim
authors.forename: R
authors.initials: R
authors.lastname: Garand
authors.forename: B
authors.initials: B
authors.lastname: Bray
authors.forename: G
authors.initials: G
authors.lastname: Leverger
authors.forename: G
authors.initials: G
authors.lastname: Flandrin
authors.forename: R
authors.initials: R
authors.lastname: Berger
mesh_terms: D002648:Child; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000235:genetics / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000473:pathology*; D012008:Recurrence; D014178:Translocation, Genetic
vernacular_title: Rechute sous forme monoblastique (M5a) d'une leucémie aiguë myéloblastique (M2) avec t(8;21).