[Evaluation of the radioprotective action of mexamine based on the cellularity index of the rat thymus].
Tie administration of mexamine leads to emigration of thymus cells levelling the radioprotective effect of the compound as determined by total cellularity of the organ. Processes of thymus cell depletion were additive after the effect of mexamine and ionizing radiation. It was found possible to estimate the radioprotective efficiency of mexamine with regard to thymus tissue cellularity diminution after the administration of the preparation.
Kormer
Z S
ZS
Rozhdestvenskiĭ
L M
LM
D008735:5-Methoxytryptamine / Q000627:therapeutic use*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D008297:Male; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D051381:Rats; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects* / Q000528:radiation effects; D013997:Time Factors; D014363:Tryptamines / Q000627:therapeutic use*
D011837:Radiation-Protective Agents; D014363:Tryptamines; D008735:5-Methoxytryptamine
Otsenka radiozashchitnogo deĭstviia meksamina po pokazateliu kletochnosti timusa krys.