Evaluation of the anterograde amnesic effect of rectally administered diazepam in the sedated pedodontic patient.
Randomly, a dosage of 0.6 mg/kg of either diazepam in solution or sodium chloride was dispensed rectally to twelve preschool children. Before the local anesthetic injection, each child was shown a toy and, before dismissal, asked to identify the toy displayed earlier. Amnesia was observed in the majority of children during the diazepam treatment appointment.
Flaitz
C M
CM
Nowak
A J
AJ
Hicks
M J
MJ
D000647:Amnesia / Q000139:chemically induced; D000766:Anesthesia, Dental; D000772:Anesthesia, Local; D002648:Child; D002652:Child Behavior / Q000187:drug effects; D002675:Child, Preschool; D003299:Cooperative Behavior / Q000187:drug effects; D003975:Diazepam / Q000008:administration & dosage* / Q000494:pharmacology; D004311:Double-Blind Method; D006801:Humans; D008568:Memory / Q000187:drug effects*; D011939:Mental Recall / Q000187:drug effects*; D010919:Placebos; D011229:Preanesthetic Medication; D013488:Suppositories
D010919:Placebos; D013488:Suppositories; D003975:Diazepam