Biological activity of lipopolysaccharides from oral Selenomonas.
Lipopolysaccharides (LPSs) were extracted by phenol-water from three oral strains of Selenomonas. The preparations were tested for the ability to induce a blastogenic response in cultures of spleen cells from normal and nude BALB/c mice, to activate guinea pig complement and the clotting enzyme system of Limulus polyphemus amoebocytes, and to kill Actinomycin-D treated mice. The capacity of the three LPSs was comparable to that of enterobacterial LPS.
Hofstad
T
T
Naess
V
V
Skaug
N
N
D000818:Animals; D003167:Complement Activation / Q000187:drug effects; D006168:Guinea Pigs; D008033:Limulus Test; D008070:Lipopolysaccharides / Q000276:immunology* / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D008934:Mitogens; D011548:Pseudomonadaceae / Q000276:immunology*; D013154:Spleen / Q000166:cytology
D008070:Lipopolysaccharides; D008934:Mitogens