Neuropsychological effects of antihypertensive drugs.
Antihypertensive medications are all associated with adverse reactions, and the elderly patient may be particularly sensitive. In a large longitudinal follow up study in an aged population, beta-blockers were shown to have caused no greater impairment of cognitive function or mood when compared to a control population. alpha-Methyldopa did interfere with some measures of neuropsychological functioning.
Wurzelmann
J
J
Department of Medicine, Columbia Presbyterian Medical Center, New York, New York.
Frishman
W H
WH
Aronson
M
M
Masur
D
D
Ooi
W L
WL
D000339:Affect / Q000187:drug effects; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003072:Cognition Disorders / Q000139:chemically induced; D003863:Depression / Q000139:chemically induced; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000523:psychology; D008297:Male; D008750:Methyldopa / Q000009:adverse effects / Q000627:therapeutic use; D009483:Neuropsychological Tests; D011433:Propranolol / Q000009:adverse effects / Q000627:therapeutic use
D000959:Antihypertensive Agents; D008750:Methyldopa; D011433:Propranolol