title: [Effect of cholesterol on the level of ascorbic acid in the plasma and tissues of rabbits].
abstract: Studies were carried out on 10 rabbits divided into two groups. Group I was fed on a physiological diet, group II was given additionally 200 mg of cholesterol daily. After 2 weeks the rabbits were decapitated and, having prepared the tissues according to Zannoni, the level of vitamin C was determined in the plasma, liver and intestinal wall by the method of Roe-Kuenther. It was shown that the diet rich in cholesterol caused a decrease in the level of vitamin C in the organism. The level of ascorbic acid decreased by 57% in the liver and plasms, by 52% in the wall of the caecum, whereas by 30% in the wall of the jejunum. A high level of cholesterol in the organism seems to increase its demand for vitamin C.
authors.affiliation: Instytut Nauk Fizjologicznych AR w Lublinie.
authors.forename: B
authors.initials: B
authors.lastname: Nagórna-Stasiak
authors.forename: M
authors.initials: M
authors.lastname: Wawrzeńska
authors.forename: R
authors.initials: R
authors.lastname: Kopeć
authors.forename: W
authors.initials: W
authors.lastname: Lietz
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000097:blood / Q000378:metabolism*; D001206:Ascorbic Acid Deficiency / Q000209:etiology*; D002432:Cecum / Q000378:metabolism; D002791:Cholesterol, Dietary / Q000009:adverse effects*; D007583:Jejunum / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D011817:Rabbits
chemical_list: D002791:Cholesterol, Dietary; D001205:Ascorbic Acid
vernacular_title: Wpływ cholesterolu na poziom kwasu askorbowego w osoczu i tkankach królików.