Assessment of the systemic distribution and toxicity of formaldehyde following pulpotomy treatment: Part two.
The active constituents of formocresol, formaldehyde and cresol, are known toxic agents. The authors administered increments of formaldehyde until systemic morbidity was demonstrated so that tissue damage could be equated with the number of concurrent pulpotomies required to achieve a toxic body load.
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D000469:Alkaline Phosphatase / Q000652:urine; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001806:Blood Urea Nitrogen; D005557:Formaldehyde / Q000097:blood / Q000378:metabolism / Q000633:toxicity*; D007770:L-Lactate Dehydrogenase / Q000652:urine; D008099:Liver / Q000378:metabolism; D008297:Male; D011507:Proteinuria / Q000652:urine; D011672:Pulpotomy; D051381:Rats; D014018:Tissue Distribution
D005557:Formaldehyde; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase