title: Assessment of the systemic distribution and toxicity of formaldehyde following pulpotomy treatment: Part two.
abstract: The active constituents of formocresol, formaldehyde and cresol, are known toxic agents. The authors administered increments of formaldehyde until systemic morbidity was demonstrated so that tissue damage could be equated with the number of concurrent pulpotomies required to achieve a toxic body load.
authors.forename: D M
authors.initials: DM
authors.lastname: Ranly
authors.forename: D
authors.initials: D
authors.lastname: Horn
mesh_terms: D000469:Alkaline Phosphatase / Q000652:urine; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001806:Blood Urea Nitrogen; D005557:Formaldehyde / Q000097:blood / Q000378:metabolism / Q000633:toxicity*; D007770:L-Lactate Dehydrogenase / Q000652:urine; D008099:Liver / Q000378:metabolism; D008297:Male; D011507:Proteinuria / Q000652:urine; D011672:Pulpotomy; D051381:Rats; D014018:Tissue Distribution
chemical_list: D005557:Formaldehyde; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase