title: [Karyotype in fortuitous familial meningioma. Report of 2 cases].
abstract: The authors report a case of two sisters affected of intracranial meningioma, with no evidence of von Recklinghausen's disease. A study of the karyotype has been performed in the patients and in their family; in one sister we have found a pericentric inversion of one chromosome 9. The possible role of the chromosomal abnormality in the develop of familial meningioma is discussed.
authors.affiliation: Dipartimento di Scienze Neurologiche, Cattedra di Neurochirurgia II, Università La Sapienza, Roma.
authors.forename: M
authors.initials: M
authors.lastname: Acqui
authors.forename: L
authors.initials: L
authors.lastname: Mastronardi
authors.forename: L
authors.initials: L
authors.lastname: Ferrante
mesh_terms: D000328:Adult; D007446:Chromosome Inversion; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D007621:Karyotyping; D008577:Meningeal Neoplasms / Q000235:genetics*; D008579:Meningioma / Q000235:genetics*
vernacular_title: Il cariotipo nei meningiomi familiari "occasionali". Osservazione di due casi.