title: Threonyl-tRNA synthetase gene maps close to leucyl-tRNA synthetase gene on human chromosome 5.
abstract: The structural gene for threonyl-tRNA synthetase was mapped to human chromosome 5 by an analysis of the isoelectric focusing patterns of this enzyme from human X Chinese hamster interspecific somatic cell hybrids. The threonyl-tRNA synthetase gene is the fourth of seven aminoacyl-tRNA synthetase genes mapped in humans to be assigned to this chromosome. Regional mapping studies showed that the threonyl-tRNA synthetase gene is on the short arm of chromosome 5, p13-cen, and is close to, but separable from, the gene for leucyl-tRNA synthetase which maps to 5cen-5q11.
authors.forename: S C
authors.initials: SC
authors.lastname: Gerken
authors.forename: J J
authors.initials: JJ
authors.lastname: Wasmuth
authors.forename: S M
authors.initials: SM
authors.lastname: Arfin
mesh_terms: D000604:Amino Acyl-tRNA Synthetases / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D006224:Cricetinae; D005796:Genes; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D007935:Leucine-tRNA Ligase / Q000235:genetics*; D013914:Threonine-tRNA Ligase / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D000604:Amino Acyl-tRNA Synthetases; D013914:Threonine-tRNA Ligase; D007935:Leucine-tRNA Ligase