Foveal and non-foveal measures of short wavelength sensitive pathways in glaucoma and ocular hypertension.
Blue-sensitive cone thresholds (the ability to detect blue test lights presented on a bright yellow background) were measured to examine foveal and central vision field sensitivity in groups of 33 glaucoma, 31 ocular hypertension (OHT) and 24 age matched normal subjects. Results showed these thresholds were substantially reduced (in all areas tested) for the glaucoma group (approximately 0.8 log units) and less reduced for the OHT group (approximately 0.2 log units), when compared to the normal group threshold. Measures of red-sensitive and green-sensitive cone thresholds showed no difference for all three groups. Furthermore, 16% of the OHT group showed visual field abnormalities for the blue-sensitive cone threshold measure. We conclude that efforts to detect early function loss in glaucoma and OHT could be improved using these measures in clinical practice.
Heron
G
G
Department of Ophthalmic Optics, Glasgow College of Technology, U.K.
Adams
A J
AJ
Husted
R
R
D003118:Color Perception / Q000502:physiology*; D005584:Fovea Centralis / Q000503:physiopathology; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D009798:Ocular Hypertension / Q000503:physiopathology*; D012684:Sensory Thresholds / Q000502:physiology; D013053:Spectrophotometry; D014794:Visual Fields