[Synthetic studies of polyene macrolide antibiotics. 1. Synthesis of C1-C6- and C7-C12 fragments of amphotericin B from carbohydrate precursors].
Strategy of synthesis of polyene macrolide antibiotic amphotericin B using carbohydrates as starting material is discussed. The C1-C6 and C7-C12 fragments of amphotericin B are synthesized.
Sviridov
A F
AF
Romanovich
A Iu
AIu
Chizhov
O S
OS
D000666:Amphotericin B / Q000138:chemical synthesis*; D002241:Carbohydrates; D055598:Chemical Phenomena; D002621:Chemistry; D008968:Molecular Conformation; D011090:Polyenes / Q000138:chemical synthesis
D002241:Carbohydrates; D011090:Polyenes; D000666:Amphotericin B
Sinteticheskie issledovaniia v riadu polienovykh makrolidnykh antibiotikov. 1. Sintez C1-C6- i C7-C12 fragmentov amfoteritsina B iz uglevodnykh predshestvennikov.