title: Y-190, a DNA probe for the sensitive detection of Y-derived marker chromosomes and mosaicism.
abstract: A DNA probe (Y-190) is described that specifically hybridizes with repeated DNA sequences in the short arm of the human Y chromosome. The suitability of Y-190 to detect Y-derived DNA is shown in two patients with a 45,X/46,X+ marker karyotype and in a third patient previously described as having a 45,X karyotype.
authors.forename: U
authors.initials: U
authors.lastname: Müller
authors.forename: T A
authors.initials: TA
authors.lastname: Donlon
authors.forename: S M
authors.initials: SM
authors.lastname: Kunkel
authors.forename: M
authors.initials: M
authors.lastname: Lalande
authors.forename: S A
authors.initials: SA
authors.lastname: Latt
mesh_terms: D004247:DNA / Q000235:genetics; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008297:Male; D009030:Mosaicism; D009693:Nucleic Acid Hybridization; D012729:Sex Chromosome Aberrations / Q000175:diagnosis* / Q000235:genetics; D014960:X Chromosome; D014998:Y Chromosome
chemical_list: D005819:Genetic Markers; D004247:DNA