title: [Diagnostic significance of the determination of IgE in food allergy].
abstract: The total level of IgE was determined in 84 patients with food allergy and in 19 healthy individuals. The level of IgE was significantly elevated in food allergy reflecting a degree of body sensitization. The absence of complete correlation between the clinical signs of disease and the blood level of IgE could depend upon the involvement of IgG-mediated allergic reactions in the pathogenesis of disease. Specific antibodies to ovalbumin of the IgG class were detected in 18 of 25 patients. Certain correlation between a therapeutic clinical effect and the time course of the serum level of IgE was observed.
authors.forename: A M
authors.initials: AM
authors.lastname: Nogaller
authors.forename: A S
authors.initials: AS
authors.lastname: Luniakov
authors.forename: L I
authors.initials: LI
authors.lastname: Gridneva
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D011852:Radioallergosorbent Test
chemical_list: D007073:Immunoglobulin E
vernacular_title: Diagnosticheskoe znachenie opredeleniia immunoglobulina E pri pishchevoĭ allergii.