title: Osteomyelitis and septic arthritis in premature infant.
abstract: A premature infant girl was born at 26 weeks' gestation by normal spontaneous vaginal delivery. After suffering from anemia, hyperbilirubinemia, and respiratory distress syndrome, she developed Pseudomonas aeruginosa sepsis of the right knee at the age of 68 days. She was treated with daily knee aspirations, antibiotic joint instillation, and intravenous antibiotics, based on culture and sensitivity reports. Although the patient did not respond to this treatment for two weeks, surgical incision and drainage with continued intravenous antibiotics finally resulted in a complete cure of the infection and restoration of full range of motion of the knee joint.
authors.affiliation: Department of Surgery, Methodist Hospital, Brooklyn, NY.
authors.forename: B
authors.initials: B
authors.lastname: Goldstein
authors.forename: P
authors.initials: P
authors.lastname: Manolas
authors.forename: J W
authors.initials: JW
authors.lastname: Silver
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000150:complications* / Q000188:drug therapy / Q000601:surgery; D004322:Drainage; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy / Q000601:surgery; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000382:microbiology*; D010019:Osteomyelitis / Q000150:complications* / Q000188:drug therapy; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000601:surgery; D011859:Radiography
chemical_list: D000900:Anti-Bacterial Agents