An intervention study using thiabendazole suspension against Strongyloides fuelleborni-like infections in Papua New Guinea.
In an isolated rural community in Papua New Guinea, 88 children were found to be infected with Strongyloides cf. fuelleborni; 50 of these also had hookworm infections. Their ages ranged from one to 124 months and all were treated with thiabendazole suspension, 25 mg/kg twice daily for 3 days. 2 patients with Strongyloides and 5 with hookworm were still passing ova 2 weeks after treatment although their egg counts were lower or the same as the pre-treatment counts. 26 children experienced some side effects from the drug, vomiting being the most common; in none did side effects prevent completion of therapy. No association between Strongyloides egg load and nutritional status, hepatosplenomegaly, respiratory ailments, oedema or serum albumin levels was found.
Barnish
G
G
Papua New Guinea Institute of Medical Research, Goroka.
Barker
J
J
D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000469:parasitology; D005260:Female; D006725:Hookworm Infections / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009752:Nutritional Status; D010219:Papua New Guinea; D010270:Parasite Egg Count; D013322:Strongyloidiasis / Q000150:complications / Q000188:drug therapy*; D013827:Thiabendazole / Q000627:therapeutic use*
D013827:Thiabendazole