[Changes in the stromal elements of the sympathetic ganglia in chemical sympathectomy by guanethidine].
As demonstrates histofluorescent, light optic and electron microscopic investigation concerning changes in the connective tissue of the cranial cervical, cervico-thoracic, the 2d and 3d thoracic sympathetic ganglia in white rats under guanethidine effect, there is an outgrowth of the connective tissue stroma of the ganglia and its infiltration with lymphocytes, macrophages and other cells of the leucocytic line with formation of cavities in these zones. The facts described are considered as morphological demonstration of certain autoimmune reactions of the ganglionic stroma, developing in response to certain changes of the antigenic properties of the ganglionic tissue elements under guanethidine effect.
Sluka
B A
BA
Zhuk
O N
ON
D000818:Animals; D000831:Animals, Newborn; D003238:Connective Tissue / Q000187:drug effects / Q000648:ultrastructure; D005728:Ganglia, Sympathetic / Q000187:drug effects* / Q000648:ultrastructure; D006145:Guanethidine; D008854:Microscopy, Electron; D009474:Neurons / Q000187:drug effects / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D013563:Sympathectomy, Chemical
D006145:Guanethidine
Izmeneniia élementov stromy v simpaticheskikh gangliiakh pri khimicheskoĭ desimpatizatsii guanetidinom.