Human leucocyte antigen and coronary artery spasm.
To elucidate possible genetic links in the pathogenesis of coronary artery spasm, we investigated the frequencies of human leucocyte antigen in 37 patients with variant angina and 236 unrelated healthy controls. We found no significant differences in human leucocyte antigen frequencies between the patients and the controls. These results may suggest that genetic factors in linkage disequilibrium with human leucocyte antigen may not be involved in the pathogenesis of coronary artery spasm.
Shimokawa
H
H
Toyoda
K
K
Matsumoto
T
T
Sato
H
H
Kikuchi
Y
Y
Nakamura
M
M
D000788:Angina Pectoris, Variant / Q000235:genetics*; D044466:Asian People; D003329:Coronary Vasospasm / Q000235:genetics; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D006684:HLA-DR Antigens / Q000235:genetics; D006801:Humans; D007564:Japan; D008297:Male
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D006684:HLA-DR Antigens