title: Comparison of flupirtine and indomethacin on frusemide-induced diuresis.
abstract: A single oral dose of flupirtine maleate, a novel analgesic agent, did not antagonize significantly the diuretic action of frusemide when compared with indomethacin and placebo in normal human volunteers.
authors.affiliation: Department of Clinical Pharmacology, St Bartholomew's Hospital, London, UK.
authors.forename: A
authors.initials: A
authors.lastname: Johnston
authors.forename: S J
authors.initials: SJ
authors.lastname: Warrington
authors.forename: P
authors.initials: P
authors.lastname: Turner
authors.forename: H
authors.initials: H
authors.lastname: Riethmuller-Winzen
mesh_terms: D000328:Adult; D000631:Aminopyridines / Q000494:pharmacology*; D000700:Analgesics / Q000494:pharmacology*; D004231:Diuresis / Q000187:drug effects*; D004311:Double-Blind Method; D005260:Female; D005665:Furosemide / Q000037:antagonists & inhibitors*; D006801:Humans; D007213:Indomethacin / Q000494:pharmacology*; D008297:Male; D011897:Random Allocation
chemical_list: D000631:Aminopyridines; D000700:Analgesics; D005665:Furosemide; C034161:flupirtine; D007213:Indomethacin