title: [Various characteristics of proteins from HeLa cella specifically binding to the human ALU sequence].
abstract: Two proteins with molecular weights of 40 and 80 kDa which are able to bind human Alu-repeat in a sequence-specific manner were found in HeLa nuclear extracts. The proteins were partially purified by column chromatography on DEAE-cellulose, phosphocellulose and FPLC MonoQ sorbent. One of the Alu-binding proteins (ABP2 with m. w. of 80 kDa) was found to bind the sequence within the Alu-repeat that has a homology with the T-antigen binding site of SV40, suggesting that ABP2 is the cellular analog of SV40 T-antigen.
authors.forename: L M
authors.initials: LM
authors.lastname: Perelygina
authors.forename: N V
authors.initials: NV
authors.lastname: Tomilin
authors.forename: O I
authors.initials: OI
authors.lastname: Podgornaia
mesh_terms: D002848:Chromatography, DEAE-Cellulose; D004268:DNA-Binding Proteins / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D006367:HeLa Cells; D006801:Humans; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004268:DNA-Binding Proteins
vernacular_title: Nekotorye kharakteristiki belkov iz kletok HeLa, spetsificheski sviazyvaiushchikh ALU-posledovatel'nost' cheloveka.