title: Evaluation of blood pressure control after bilateral glomectomy: effects of propranolol treatment.
abstract: The effects of bilateral glomectomy on arterial blood pressure and heart rate and the response to the pressor tests were studied in a women of 37. Arterial pressure and ECG were recorded by the continuous unrestricted Oxford method. Hypotension, increased blood pressure variability and tachycardia rapidly developed 2 days after surgery, indicating sympathetic hyperactivity and/or deactivation of vagal tone. Wide blood pressure fluctuations were present on standing and abnormal blood pressure responses to head up tilting and to the Valsalva maneuver were observed reflecting a less prompt and precise control of blood pressure. Treatment with propranolol reduced tachycardia and blood pressure variability. After 5 and 17 months of this therapy propranolol was withheld for 36 h. Tachycardia was still present and blood pressure fluctuations were recorded on assuming the upright posture. However, the heart rate and pressure response to the Valsalva maneuver were normal after 17 months, indicating an improvement of the reflex control of blood pressure.
authors.affiliation: Institute of Clinical Medicine, University of Padua, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Palatini
authors.forename: A C
authors.initials: AC
authors.lastname: Pessina
authors.forename: E
authors.initials: E
authors.lastname: Casiglia
authors.forename: G
authors.initials: G
authors.lastname: Sperti
authors.forename: P
authors.initials: P
authors.lastname: Mormino
authors.forename: A
authors.initials: A
authors.lastname: Di Marco
authors.forename: E
authors.initials: E
authors.lastname: Ventura
authors.forename: R
authors.initials: R
authors.lastname: Gava
authors.forename: C
authors.initials: C
authors.lastname: Dal Palù
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002344:Carotid Body / Q000502:physiology / Q000601:surgery*; D002345:Carotid Body Tumor / Q000601:surgery; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D011183:Postoperative Complications / Q000188:drug therapy; D011433:Propranolol / Q000627:therapeutic use*; D012021:Reflex, Abnormal / Q000503:physiopathology; D013610:Tachycardia / Q000209:etiology; D014630:Vagus Nerve / Q000503:physiopathology; D014636:Valsalva Maneuver
chemical_list: D011433:Propranolol