title: Unusual vascular malformation of the kidney in both twins of a monozygotic pair: short case report.
abstract: A case of double bilateral renal vessels in both twins of a MZ pair is reported for the first time. Even in non-twins, the anomalies reported so far involved the inferior polar arteries in agreement with the embryological development. The two male twins, examined at the age of 14 years, had simultaneously developed a marked hypertension at the age of 7 years. Zygosity was determined by blood group and HLA analysis and various clinical tests were carried out to diagnose the condition. It is suggested that the anomaly is the result of a genetically induced early block in embryonic development.
authors.affiliation: Fourth Chair of Clinical Medicine, School of Medicine, First University of Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Mastroberardino
authors.forename: A
authors.initials: A
authors.lastname: Sciarra
authors.forename: R
authors.initials: R
authors.lastname: Gualtieri
authors.forename: C
authors.initials: C
authors.lastname: Di Fusco
authors.forename: P
authors.initials: P
authors.lastname: Grammatico
authors.forename: G
authors.initials: G
authors.lastname: Del Porto
mesh_terms: D000293:Adolescent; D004200:Diseases in Twins; D006801:Humans; D006973:Hypertension / Q000235:genetics; D008297:Male; D012077:Renal Artery / Q000002:abnormalities*; D014427:Twins; D014430:Twins, Monozygotic