title: Effect of imidazoquinazolinones on tumor cells in the circulation.
abstract: Of several imidazoquinazolinones, Anagrelide was found to be the most effective compound to inhibit platelet aggregation and to increase circulation time of intravenously injected tumor cells resulting in metastasis formation.
authors.forename: J L
authors.initials: JL
authors.lastname: Ambrus
authors.forename: C M
authors.initials: CM
authors.lastname: Ambrus
authors.forename: H
authors.initials: H
authors.lastname: Gastpar
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D005343:Fibrinolytic Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009360:Neoplastic Cells, Circulating; D010974:Platelet Aggregation / Q000187:drug effects; D011799:Quinazolines / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D005343:Fibrinolytic Agents; D011799:Quinazolines; C021139:anagrelide