Mapping thyrotropin beta subunit gene in man and mouse.
Thyrotropin (TSH) is composed of two subunits: alpha and beta. Previously, we have mapped the TSH alpha gene to human chromosome 6 and mouse chromosome 4. In this study we have located the human TSH beta gene on chromosome 1 and the mouse TSH beta gene to chromosome 3. These data suggest that the TSH beta gene lies in a conserved linkage group with the genes for amylase 1 and 2, nerve growth factor, and the protooncogene Nras.
Naylor
S L
SL
Sakaguchi
A Y
AY
McDonald
L
L
Todd
S
S
Lalley
P A
PA
Shows
T B
TB
Chin
W W
WW
D000818:Animals; D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D008040:Genetic Linkage; D006801:Humans; D006822:Hybrid Cells; D051379:Mice / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D013972:Thyrotropin / Q000235:genetics*
D013972:Thyrotropin; D004247:DNA