title: Phototoxicity from systemic agents.
abstract: Phototoxicity caused by systemic agents has been well described in the literature for only a handful of medications. Diagnosis rests initially upon the clinical recognition of a photodistributed eruption. Thereafter, histopathology and light testing with the patient on and off of the suspected medication should confirm the clinical suspicion. The creation of accurate and up-to-date tables of medications causing phototoxicity rests upon adequate documentation from the literature and thorough laboratory investigation of newly suspected agents.
authors.forename: A C
authors.initials: AC
authors.lastname: Toback
authors.forename: J E
authors.initials: JE
authors.lastname: Anders
mesh_terms: D000638:Amiodarone / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D002746:Chlorpromazine / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D011564:Furocoumarins / Q000009:adverse effects; D006415:Hematoporphyrins / Q000009:adverse effects; D006801:Humans; D015474:Isotretinoin; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D012867:Skin / Q000503:physiopathology; D000077145:Sulfanilamide; D013424:Sulfanilamides / Q000009:adverse effects; D014212:Tretinoin / Q000009:adverse effects
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D004232:Diuretics; D011564:Furocoumarins; D006415:Hematoporphyrins; D013424:Sulfanilamides; D000077145:Sulfanilamide; D014212:Tretinoin; D015474:Isotretinoin; D000638:Amiodarone; D002746:Chlorpromazine