title: Evaluation of a program to overcome vitamin A and iron deficiencies in areas of poverty in Minas Gerais, Brazil.
abstract: Randon samples of children from both sexes from Belo Horizonte, the capital City, and from Turmalina, Jequitinhonha Valley, Minas Gerais, Brazil, were submitted to nutritional evaluation before and after the intervention "Program to Overcome Vitamin A and Iron Deficiencies in Areas of Poverty in Minas Gerais, Brazil". After the first examination, all the children received, with an interval of 180 days, a single oral dose of vitamin A, oral iron sulfate during 50 days, and 200 mg of Mebendazol/day for three days. Thirty days after ending administration of the third dose of medicine, the children were subjected to a new evaluation. In Belo Horizonte, the first evaluation revealed a high prevalence of deficient and low values of vitamin A in preschool children (21.5%) and school children (21.7%). A small prevalence of low hematocrit values was also observed in both groups. Deficient and low values of hemoglobin were found as well in 21.5% of preschool children and in 17.5% of school children. The second evaluation, practiced 30 days after the third dose of medicine, showed a small incidence of low vitamin A values (4.3% in preschool children and 2.9% in school children) and low hemoglobin values (6.5% in preschool children and 2.9% in school children). No deficient values of hemoglobin and vitamin A were observed. Concerning the hematocrit value, only one school child presented a low value at the second evaluation. On the other hand, in Jequitinhonha Valley, five cases of Bitot spot with conjunctival xerosis, two cases of corneal xerosis, and one case of keratomalacia were detected at the first examination. Thirty days after ending the third dose of medicine, only one corneal scar was observed. Only a small number of children with deficient and low levels of vitamin A and hemoglobin was found in the final evaluation (less than 8%), while this number was high at the first evaluation (above 38 and 12%, respectively). These results show the efficiency of the intervention Program in relation to hypovitaminosis A and iron anemia prevention. The Program is now being implemented by the Brazilian Ministry of Health.
authors.affiliation: Faculdade de Ciencias Médicas de Minas Gerais, FELUMA, Belo Horizonte, Brazil.
authors.forename: R L
authors.initials: RL
authors.lastname: Araujo
authors.forename: M B
authors.initials: MB
authors.lastname: Araujo
authors.forename: R D
authors.initials: RD
authors.lastname: Machado
authors.forename: A A
authors.initials: AA
authors.lastname: Braga
authors.forename: B V
authors.initials: BV
authors.lastname: Leite
authors.forename: J R
authors.initials: JR
authors.lastname: Oliveira
mesh_terms: D000293:Adolescent; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D005260:Female; D005296:Ferrous Compounds / Q000008:administration & dosage*; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D000090463:Iron Deficiencies; D008297:Male; D008463:Mebendazole / Q000008:administration & dosage*; D011247:Pregnancy; D011897:Random Allocation; D012041:Regional Medical Programs; D014801:Vitamin A / Q000008:administration & dosage* / Q000097:blood; D014802:Vitamin A Deficiency / Q000517:prevention & control*
chemical_list: D005296:Ferrous Compounds; D006454:Hemoglobins; D014801:Vitamin A; C020748:ferrous sulfate; D008463:Mebendazole