Preoperative cervical dilatation for first trimester induced abortion: comparison of two prostaglandin analogues.
The present study compares two methods of local application of prostaglandins prior to surgical abortion in the first trimester. Fifty patients were treated with a vaginal tablet of Gemeprost (E1 analogue); 50 others by the intra-cervical application of PGF2 alpha gel. Gemeprost was found to be superior to the PGF2 alpha gel. Several hypotheses are formulated to explain this observation. The side effects of the two methods are compared and discussed.
Mao
W T
WT
Huber
M
M
Bader
M
M
Krauer
F
F
D000028:Abortion, Induced / Q000379:methods*; D000287:Administration, Topical; D000328:Adult; D000527:Alprostadil / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D002584:Cervix Uteri / Q000187:drug effects*; D004106:Dilatation / Q000379:methods; D015237:Dinoprost; D005260:Female; D005782:Gels; D006801:Humans; D010146:Pain / Q000503:physiopathology; D010298:Parity; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011446:Prospective Studies; D011460:Prostaglandins F / Q000008:administration & dosage* / Q000009:adverse effects; D013607:Tablets
D005782:Gels; D011460:Prostaglandins F; D013607:Tablets; C021182:gemeprost; D015237:Dinoprost; D000527:Alprostadil