HLA antigen CW3 combined with unexplained high transcortin levels is found in patients with acute lymphoblastic leukemia but not in their parents, sibs and offspring.
ALL patients with an unexplained high transcortin level (greater than or equal to 3 SD above the normal mean) have a higher incidence of HLA antigen Cw3 than patients with a lower transcortin level. Although both factors are inheritable, their combination occurs only rarely in the family members of these patients.
de Moor
P
P
Louwagie
A
A
D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015236:HLA-C Antigens; D006801:Humans; D007945:Leukemia, Lymphoid / Q000097:blood / Q000235:genetics / Q000276:immunology*; D008297:Male; D014156:Transcortin / Q000378:metabolism*
D006680:HLA Antigens; D015236:HLA-C Antigens; C038653:HLA-C*03 antigen; D014156:Transcortin