title: Scleromyxedema and inflammatory myopathy: a clinicopathologic study of three patients.
abstract: Scleromyxedema (lichen myxedematosus) is a rare cutaneous manifestation in patients with idiopathic inflammatory myopathy. The clinical and histological findings in three patients with this association are presented. Two patients had a severe inflammatory polymyopathy which responded incompletely to corticosteroid therapy, while in the third, who developed esophageal carcinoma, the myopathy was relatively mild and the skin changes were the dominant feature. The occurrence of scleromyxedema in patients with inflammatory myopathy appears to carry a poor prognosis.
authors.forename: J M
authors.initials: JM
authors.lastname: Harvey
authors.forename: P J
authors.initials: PJ
authors.lastname: Zilko
authors.forename: P S
authors.initials: PS
authors.lastname: Cheah
authors.forename: F L
authors.initials: FL
authors.lastname: Mastaglia
authors.forename: V J
authors.initials: VJ
authors.lastname: Ojeda
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D009220:Myositis / Q000150:complications* / Q000473:pathology; D011379:Prognosis; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology