title: Antibody to collagen type I in periodontal disease.
abstract: Serum antibody levels to human collagen Type I were measured in 97 patients with periodontal disease (Russell Periodontal Index 1.0-7.0) and 57 control subjects (Periodontal Index less than 1.0) using an enzyme-linked immunosorbent assay, which had been standardized with antisera prepared against human collagen Type I in rabbits. Absorption studies were used to confirm the specificity of antibodies to human Type I collagen. Levels of antibody to Type I collagen detected in patients were higher (P less than 0.001) than in the control subjects.
authors.forename: A
authors.initials: A
authors.lastname: Ftis
authors.forename: G
authors.initials: G
authors.lastname: Singh
authors.forename: A E
authors.initials: AE
authors.lastname: Dolby
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D003094:Collagen / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000276:immunology*; D010512:Periodontal Index
chemical_list: D001323:Autoantibodies; D003094:Collagen