Assignment of the gene for carboxypeptidase A to human chromosome 7q22----qter and to mouse chromosome 6.
A rat cDNA probe for preprocarboxypeptidase A was used to follow the segregation of the human gene for carboxypeptidase A (CPA) in 49 human X mouse somatic cell hybrids using Southern filter hybridization techniques. CPA was assigned to human chromosome 7q22----qter. Similarly, the probe was used to follow the segregation of the mouse gene for carboxypeptidase A (Cpa) in 19 mouse X Chinese hamster somatic cell hybrids. Cpa was assigned to mouse chromosome 6. The gene for carboxypeptidase A forms part of a syntenic group that is conserved in man and mouse.
Honey
N K
NK
Sakaguchi
A Y
AY
Lalley
P A
PA
Quinto
C
C
Rutter
W J
WJ
Naylor
S L
SL
D000818:Animals; D002268:Carboxypeptidases / Q000235:genetics*; D043422:Carboxypeptidases A; D002874:Chromosome Mapping; D002906:Chromosomes, Human, 6-12 and X; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000235:genetics; D004587:Electrophoresis, Agar Gel; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D051379:Mice
D005819:Genetic Markers; D004247:DNA; D002268:Carboxypeptidases; D043422:Carboxypeptidases A