title: In vitro investigations with selective adsorbents for IgE and IgM.
abstract: In vitro studies were carried out with IM-T. This adsorbent consists of polyvinyl alcohol joined with tryptophan side chains and was delivered by ASAHI Medical Co., Ltd., Tokyo/Japan. It was found that IM-T binds immunoglobulins G and M and also immune complexes only moderately but IgE was adsorbed in remarkable amounts. A clear dose-dependent was adsorbed in remarkable amounts. A clear dose-dependent manner of the IgE adsorption could be stated. Kinetic studies revealed that the binding was only slow and gradual.
authors.affiliation: Department of Internal Medicine, Wilhelm-Pieck-University, Rostock, GDR.
authors.forename: E
authors.initials: E
authors.lastname: Behm
authors.forename: T
authors.initials: T
authors.lastname: Kuroda
authors.forename: N
authors.initials: N
authors.lastname: Yamawaki
authors.forename: N
authors.initials: N
authors.lastname: Tsuda
authors.forename: F
authors.initials: F
authors.lastname: Loth
authors.forename: G
authors.initials: G
authors.lastname: Schwachula
authors.forename: E
authors.initials: E
authors.lastname: Sabrowski
authors.forename: D
authors.initials: D
authors.lastname: Falkenhagen
authors.forename: H
authors.initials: H
authors.lastname: Klinkmann
mesh_terms: D000818:Animals; D000936:Antigen-Antibody Complex; D006801:Humans; D007073:Immunoglobulin E / Q000302:isolation & purification*; D007075:Immunoglobulin M / Q000302:isolation & purification*; D007164:Immunosorbents; D066298:In Vitro Techniques
chemical_list: D000936:Antigen-Antibody Complex; D007075:Immunoglobulin M; D007164:Immunosorbents; D007073:Immunoglobulin E