[Changes in the microcirculatory bed of the uterus and its regional lymph nodes during pregnancy].
In pregnant Wistar rats an essential rearrangement of the uterine blood-lymph circulatory bed has been revealed. It is possible that at the beginning of pregnancy it occurs for the change of the histiotrophic nutrition of the embryo into the hemotrophic one under effect of the trophoblast. Later on, when hemochorial relations between the mother and the fetus have been established, the continuous growth of the volumetric density and diameter of the vessels of the uterine microcirculatory bed can be connected with the intensive growth of the fetus and the extension of the yolk and allantois circulation reservoir. During these periods of pregnancy the mass of the placental labyrinth is doubled and vascularization of the extraembryonic organs increases. The circulatory changes occurring in the uterine placental zone get their reflection in the uterine regional lymph nodes. The investigation of the ultrastructural organization of endotheliocytes in the blood capillaries of the rat iliac lymph nodes during pregnancy reveals a complex of adaptive-structural rearrangements in them, first of all enlargement of the lumen in the arterial and venous parts of the capillaries, increasing fenestration of the arterial and venous parts of the capillaries, enhancing formation of micropinocytic vesicles and transendothelial canals. Thus, the complex of adaptive-compensatory rearrangements and interconnected, integrated reaction of the uterine microcirculatory bed with the analogous system of its regional iliac lymph nodes is revealed.
Borodin
Iu I
IuI
Ustiugov
E D
ED
Sklianova
N A
NA
Sklianov
Iu I
IuI
D000222:Adaptation, Physiological; D000818:Animals; D005260:Female; D008198:Lymph Nodes / Q000098:blood supply*; D008208:Lymphatic System / Q000648:ultrastructure; D008833:Microcirculation / Q000648:ultrastructure; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D051381:Rats; D013997:Time Factors; D014599:Uterus / Q000098:blood supply*
Izmeneniia mikrotsirkuliatornogo rusla matki i ee regionarnykh limfaticheskikh uzlov vo vremia beremennosti.