title: Near-haploidy in a case of plasmocytoma.
abstract: Chromosome studies of a solitary plasmocytoma in the femoral bone revealed a near-haploid chromosome number of 31-32 with a loss of one homolog of each chromosome pair except #1, #7, #9, #15, #19-21, and the sex chromosomes (XY). The cytogenetic findings have been compared with 16 cases of near-haploid neoplasms from the literature studied using banding techniques. A common feature present in 13 of the 16 cases reported was found to be disomy 21; the only chromosomes consistently present in one copy in all neoplasms were #2, #3, #4, and #5.
authors.forename: U
authors.initials: U
authors.lastname: Kristoffersson
authors.forename: H
authors.initials: H
authors.lastname: Olsson
authors.forename: D
authors.initials: D
authors.lastname: Kelly
authors.forename: M
authors.initials: M
authors.lastname: Akerman
authors.forename: F
authors.initials: F
authors.lastname: Mitelman
mesh_terms: D002869:Chromosome Aberrations; D006238:Haploidy; D006801:Humans; D007945:Leukemia, Lymphoid / Q000235:genetics; D007951:Leukemia, Myeloid / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010954:Plasmacytoma / Q000235:genetics*