The relationship between blood thiamine levels and dietary thiamine content in diabetic outpatients and healthy subjects.
Forty-six diabetic outpatients consumed (1,533 +/- 308 kcal (mean +/- SD) per day, 205 +/- 42 g of carbohydrates, 73 +/- 18 g of protein, 49 +/- 18 g of fat, and 0.05 +/- 0.34 mg of thiamine. No significant correlation was found in 46 diabetic between blood thiamine level and the intake of dietary energy, carbohydrate or thiamine. In 13 healthy subjects given prepared diets, a significant correlation was found between blood thiamine level and dietary thiamine content, thiamine content per 1,000 kcal, and 24-h urinary thiamine amount divided by urinary creatinine. When 9 healthy subjects (6 males, 3 females) consumed 1,600 kcal with 0.6 mg of thiamine for two days, their blood thiamine level was 47 +/- 29.1 ng/ml before and 29.7 +/- 7.1 ng/ml after eating the diet, showing low blood thiamine levels due to the low content of dietary thiamine. When 5 or 6 healthy female subjects consumed 1,400 kcal with 1.6 mg of thiamine or 2,000 kcal with 1.9 mg of thiamine for two days, their blood thiamine level was 45.3 +/- 4.8 ng/ml or 57.7 +/- 8.4 ng/ml before and 51.5 +/- 11.7 ng/ml or 56.4 +/- 11.7 ng/ml after eating the diets, respectively. In both diabetic outpatients and healthy subjects, a significant positive correlation was found between blood thiamine levels and dietary thiamine concentrations per 1,000 kcal, and a significant positive correlation was also found between erythrocyte transketolase activity and dietary thiamine content.(ABSTRACT TRUNCATED AT 250 WORDS)
Saito
N
N
Department of Geriatrics, Kochi Medical University, Japan.
Kimura
M
M
Kuchiba
A
A
Itokawa
Y
Y
D000328:Adult; D003920:Diabetes Mellitus / Q000097:blood*; D004032:Diet; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D002149:Energy Intake; D005260:Female; D005511:Food Handling; D006801:Humans; D008297:Male; D008875:Middle Aged; D013831:Thiamine / Q000097:blood*
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D013831:Thiamine