[Immunogenetic studies in patients with IgM rheumatoid factor negative erosive chronic polyarthritis (c.p.)].
40 patients with erosive rheumatoid arthritis (RA), 20 of whom were IgM-negative and 20 IgM-positive, were studied prospectively with regard to their association with HLA-B-CREGs (B5-, B8-, B12-, B16-, B27-CREG). We found a highly significant association of IgM-negative RA patients and B5-CREG-antigens (Chi2 = 28.6; p less than 0.001).
Bröll
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H
Haberhauer
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D000483:Alleles; D001172:Arthritis, Rheumatoid / Q000235:genetics / Q000276:immunology*; D002874:Chromosome Mapping; D005260:Female; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D015235:HLA-B Antigens; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000378:metabolism*
D006680:HLA Antigens; D015235:HLA-B Antigens; D007075:Immunoglobulin M; D012217:Rheumatoid Factor
Immungenetische Untersuchungen bei Patienten mit IgM-Rheumafaktor-negativer erosiver chronischer Polyarthritis (c.P.).