[A technic for human basophil degranulation].
We had studied the human basophil degranulation test (HBDT) in 26 cases of allergic patients with drugs (penicillin, erythromycin, josamycin) one month after their anaphylactic reaction. This test was negative in 7 cases on 8 for penicillin, positive in 8 cases on 10 for erythromycin and in 6 cases on 8 for josamycin. The failure of this test with penicillin can be explained by a sensitization to a metabolic penicillin product or to the complex hapten-carrier.
Harrabi
S
S
Laboratoire de Biologie Médicale, Sens.
Loiseau
P
P
Dehenry
J
J
D001491:Basophils / Q000378:metabolism*; D003594:Cytoplasmic Granules / Q000378:metabolism*; D004342:Drug Hypersensitivity / Q000175:diagnosis; D006373:Helminthiasis / Q000175:diagnosis; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000175:diagnosis*; D007159:Immunologic Tests
Mise au point d'une technique de dégranulation des basophiles humains.