A glycoprotein rapidly labelled with [14C]glucose present in a murine melanoma cell line.
If a murine melanoma cell line PG19 is metabolically labelled with [14C]glucose for a short time, one particular membrane component incorporates more radioactivity than the rest. This is a glycoprotein of about Mr 100,000, which is not preferentially labelled in non-malignant variants of the melanoma or in suppressed hybrid cells formed between PG19 and mouse fibroblasts.
Bramwell
M E
ME
Sir William Dunn School of Pathology, Oxford, England.
D015502:Absorptiometry, Photon; D000818:Animals; D002460:Cell Line; D004591:Electrophoresis, Polyacrylamide Gel; D005947:Glucose / Q000378:metabolism; D006023:Glycoproteins / Q000032:analysis*; D008545:Melanoma / Q000032:analysis* / Q000378:metabolism; D051379:Mice; D009363:Neoplasm Proteins / Q000032:analysis*; D014407:Tumor Cells, Cultured
D006023:Glycoproteins; D009363:Neoplasm Proteins; D005947:Glucose