title: [Genetic and ecological study of aboriginal populations of northeastern Siberia. II. Polymorphic blood systems, immunoglobulin allotypes and other genetic markers in asian eskimos. Genetic structure of Bering sea eskimos].
abstract: Blood groups, immunoglobulin allotypes, serum proteins and red cell enzymes were tested in four populations of Asiatic Eskimos. 12 of 16 gene loci studied were found to be polymorphic. Analysis of covariance and variance matrices for gene frequencies of 8 Bering Sea populations revealed major aspects of regional genetic structure. Regression of average heterozygosity on genetic distance from centroid permitted us to interpret it in the light of counterbalancing action of systematic and non-systematic pressure. Analysis of R matrix containing gene frequencies for both Eskimo and Chukchi populations revealed two different clusters - more heterogeneous Eskimo cluster and less heterogeneous Chukchi cluster. Good fit was observed between regional genetic structure, history and geography.
authors.forename: R I
authors.initials: RI
authors.lastname: Sukernik
authors.forename: V P
authors.initials: VP
authors.lastname: Vibe
authors.forename: T M
authors.initials: TM
authors.lastname: Karafet
authors.forename: L P
authors.initials: LP
authors.lastname: Osipova
authors.forename: O L
authors.initials: OL
authors.lastname: Posukh
mesh_terms: D001789:Blood Group Antigens / Q000235:genetics*; D001798:Blood Proteins / Q000235:genetics*; D004463:Ecology; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000235:genetics*; D004930:Inuit; D011110:Polymorphism, Genetic; D012800:Siberia
chemical_list: D001789:Blood Group Antigens; D001798:Blood Proteins; D005819:Genetic Markers; D007126:Immunoglobulin Allotypes
vernacular_title: Geneticheskoe i ékologicheskoe izuchenie korennykh zhiteleĭ severo-vostoka Sibiri. Soobshchenie II. Polimorfnye sistemy krovi, allotipy immunoglobulinov i drugie geneticheskie markery u aziatskikh éskimosov. Geneticheskaia struktura éskimosov Beringova moria.