title: [Clinical feature of male non-gonorrhoea urethritis and minocycline treatment of Chlamydia or Ureaplasma-infected urethritis].
abstract: Thirty-nine male patients with urethritis were studied for gonorrhoea or non-gonorrhoea infections. Only 2 patients were infected with N. gonorrhoeae, the other 37 patients were non-gonorrhoea urethritis (NGU). In 9 of these patients, C. trachomatis was identified and in 6 patients, U. urealyticum was isolated. No chlamydial urethritis was combined with ureaplasma. There was no clinical difference between chlamydia and ureaplasma infection, such as serous urethral discharge or mild pyuria. Minocycline was given orally at the dose of 200 mg daily for 7 to 42 days to these patients. Seven of the 9 patients (78%) with C. trachomatis and 7 of the 6 patients (67%) with U. urealyticum infection showed improvement of subjective and objective symptoms after minocycline. In no case, was an adverse reaction noted. Minocycline was effective in the treatment of both C. trachomatis and U. urealyticum urethral infection.
authors.affiliation: Department of Urology, Kagawa Medical College.
authors.forename: A
authors.initials: A
authors.lastname: Yasukawa
authors.forename: S
authors.initials: S
authors.lastname: Takeda
authors.forename: Y
authors.initials: Y
authors.lastname: Takeda
authors.forename: A
authors.initials: A
authors.lastname: Yasumoto
authors.forename: N
authors.initials: N
authors.lastname: Matsuoka
authors.forename: K
authors.initials: K
authors.lastname: Negayama
mesh_terms: D000328:Adult; D002690:Chlamydia Infections / Q000188:drug therapy*; D002692:Chlamydia trachomatis; D004341:Drug Evaluation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000627:therapeutic use*; D009180:Mycoplasmatales Infections / Q000188:drug therapy*; D013754:Tetracyclines / Q000627:therapeutic use*; D014509:Ureaplasma; D014526:Urethritis / Q000188:drug therapy*
chemical_list: D013754:Tetracyclines; D008911:Minocycline