title: [Simultaneous registration of pancreatic secretion profiles in endoscopic secretion sampling in patients with and without pancreatic diseases].
abstract: A method for the continuous detection of secretory profiles of human pure pancreatic juice is described. After retrograde cannulation of the D. pancreaticus the exocrine pancreas was stimulated by an intravenous infusion of secretin and a bolus injection of pancreozymin additionally. The absorbance of pancreatic juice at 280 nm was measured continuously using an Uvicord-UV-Photometer which was connected directly with a Teflon catheter localised in the main pancreatic duct. The secretory profiles obtained from patients without pancreatic diseases (n = 12) indicated a first maximum of absorbance after secretin infusion and a second one in response to pancreozymin bolus injection. Alterations of secretory profiles in patients with chronic pancreatitis (n = 10) were evident after pancreozymin administration principally.
authors.affiliation: Forschungsabteilung Gastroenterologie des Medizinisch-Poliklinischen Institutes, Karl-Marx-Universität Leipzig.
authors.forename: R
authors.initials: R
authors.lastname: Rogos
authors.forename: G
authors.initials: G
authors.lastname: Appelt
authors.forename: B
authors.initials: B
authors.lastname: Schulze
mesh_terms: D000328:Adult; D000368:Aged; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002766:Cholecystokinin; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology; D010186:Pancreatic Function Tests; D010189:Pancreatic Juice / Q000378:metabolism*; D010195:Pancreatitis / Q000473:pathology*; D012633:Secretin; D012636:Secretory Rate
chemical_list: D012633:Secretin; D002766:Cholecystokinin
vernacular_title: Simultane Registrierung von Pankreassekretionsprofilen während der endoskopischen Sekretentnahme bei Patienten mit und ohne Pankreaserkrankungen.