Isochromosome 11q in a case of Ewing's sarcoma.
A low passage Ewing's sarcoma cell line established from a metastatic lesion was cytogenetically analyzed. The modal karyotype was 44,X, -8,i(11q), -15, +12. Other cells had random chromosome aneuploidy superimposed on this karyotype. No cell had a structural rearrangement involving 11q24 or 22q12 as described in other patients with Ewing's sarcoma, but all cells had an isochromosome 11q.
Bennett
D D
DD
Garvin
A J
AJ
Killough
B W
BW
Stanley
W S
WS
D002648:Child; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002880:Chromosomes, Human, Pair 11; D005266:Femoral Neoplasms / Q000235:genetics* / Q000473:pathology; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008297:Male; D012512:Sarcoma, Ewing / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic
D005819:Genetic Markers