Comparison of the hardness change and mineral loss in enamel by dimethyl ammonium fluoride (alpha C12 DMEAHF) or NaF treatment under intra oral cariogenicity test conditions.
Changes in hardness as well as in Ca and P were determined in enamel slabs after treatment with 3% sucrose together with NaF or alpha C12 DMEAHF (both containing 0.006% F-) under Intra Oral Cariogenicity Test conditions. NaF treatment resulted in a hypermineralization of the surface of the enamel lesion suggesting formation of CaF2. Treatment with ammonium fluoride along with the same low F- concentration inhibits the caries process completely and seems to be a very promising anticaries agent.
Wöltgens
J H
JH
Van Croonenburg
E J
EJ
de Blieck-Hogervorst
J M
JM
D064751:Ammonium Compounds; D000818:Animals; D002128:Calcium Metabolism Disorders / Q000175:diagnosis*; D002327:Cariostatic Agents / Q000494:pharmacology; D002417:Cattle; D003649:Decalcification, Pathologic / Q000175:diagnosis*; D003733:Dental Caries Susceptibility; D003743:Dental Enamel / Q000187:drug effects* / Q000378:metabolism; D005459:Fluorides / Q000494:pharmacology*; D006244:Hardness; D006801:Humans; D000644:Quaternary Ammonium Compounds; D012969:Sodium Fluoride / Q000494:pharmacology*
D064751:Ammonium Compounds; D002327:Cariostatic Agents; D000644:Quaternary Ammonium Compounds; C024822:ammonium fluoride; D012969:Sodium Fluoride; D005459:Fluorides