title: Three cases of translocation (8;16)(p11;p13) observed in acute myelomonocytic leukemia: a new specific subgroup?
abstract: In three cases of acute nonlymphocytic leukemia we observed a translocation (8;16)(p11;p13); in one case it was the sole karyotypic change and in the other two cases it was associated with other structural anomalies. All three cases were nonhyperleukocytic myelomonocytic leukemias with erythrophagocytosis by some blast cells and cytochemistry results consistent with leukemic proliferation of a common monocytic-granulocytic precursor. The importance of this translocation is discussed, and the implication of band 16p13 in myelomonocytic leukemia is stressed.
authors.forename: J L
authors.initials: JL
authors.lastname: Laï
authors.forename: M
authors.initials: M
authors.lastname: Zandecki
authors.forename: J P
authors.initials: JP
authors.lastname: Jouet
authors.forename: J B
authors.initials: JB
authors.lastname: Savary
authors.forename: A
authors.initials: A
authors.lastname: Lambiliotte
authors.forename: F
authors.initials: F
authors.lastname: Bauters
authors.forename: A
authors.initials: A
authors.lastname: Cosson
authors.forename: M
authors.initials: M
authors.lastname: Deminatti
mesh_terms: D000293:Adolescent; D000328:Adult; D001853:Bone Marrow / Q000648:ultrastructure; D002871:Chromosome Banding; D002885:Chromosomes, Human, Pair 16; D002898:Chromosomes, Human, Pair 8; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000145:classification / Q000235:genetics*; D008875:Middle Aged; D014178:Translocation, Genetic
chemical_list: D005819:Genetic Markers