Trans-regulatory functions in the Abdominal-B gene of the bithorax complex.
We have investigated the functional organization of the Abdominal-B gene in the bithorax complex using the expression of the Ultrabithorax gene as an assay for Abdominal-B trans-regulatory functions. Using Polycomb mutants to relax the normal spatial control of Ultrabithorax expression, we have examined the effects of Abdominal-B mutations on the expression of Ultrabithorax protein products in parasegment 14. The results support the hypothesis that the Abdominal-B gene contains two trans-regulatory functions: the m element active in parasegments 10-13 and the r element acting exclusively in parasegment 14.
Casanova
J
J
Centro de Biologia Molecular CSIC-UAM, Facultad de Ciencias, Universidad Autonoma de Madrid, Spain.
White
R A
RA
D000818:Animals; D004330:Drosophila / Q000235:genetics; D005786:Gene Expression Regulation; D005796:Genes; D007150:Immunohistochemistry; D009154:Mutation; D013909:Thorax / Q000196:embryology*