title: [Imipenem/cilastatin sodium in the treatment of obstetric and gynecologic infections].
abstract: Imipenem/cilastatin sodium (MK-0787/MK-0791), a carbapenem antibiotic and a dehydropeptidase-I inhibitor, was administered at a dose of 500 mg/500 mg twice a day for 5 days for the treatment of obstetric and gynecologic infections. A total of 10 patients was evaluated, and the clinical results were rated as excellent in 1, good in 7 and poor in 2 patients. As a side effect, rash was observed in 1 patient but it disappeared by the third day after the treatment was discontinued. No abnormal laboratory findings were observed in our study.
authors.forename: F
authors.initials: F
authors.lastname: Doko
mesh_terms: D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy*; D015377:Cilastatin; D003521:Cyclopropanes / Q000008:administration & dosage*; D004338:Drug Combinations; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D006801:Humans; D015378:Imipenem; D008875:Middle Aged; D013845:Thienamycins / Q000008:administration & dosage*
chemical_list: D003521:Cyclopropanes; D004338:Drug Combinations; D013845:Thienamycins; D015377:Cilastatin; D015378:Imipenem