title: Experimentally induced myopia does not affect post-hatching development of the chick lens.
abstract: Myopia, as characterized by a large refractive error (e.g. -10.7 +/- 0.4 D), was induced in post-hatch chicks by a 14 day application of a goggle that was designed to blur the retinal image. In comparison to untreated eyes, the treated eye showed significant changes in wet eye weight and both axial and equatorial lengths. However, the lenses of myopic and non-myopic eyes were not significantly different in focal characteristics, light transmittance or total soluble protein content. Thus the lens neither contributes to, nor compensates for the large refractive error observed in experimentally induced myopia.
authors.affiliation: School of Optometry, University of Waterloo, Ontario, Canada.
authors.forename: R L
authors.initials: RL
authors.lastname: Pickett-Seltner
authors.forename: J
authors.initials: J
authors.lastname: Weerheim
authors.forename: J G
authors.initials: JG
authors.lastname: Sivak
authors.forename: J
authors.initials: J
authors.lastname: Pasternak
mesh_terms: D000818:Animals; D002645:Chickens; D003459:Crystallins / Q000032:analysis; D007908:Lens, Crystalline / Q000254:growth & development* / Q000503:physiopathology; D008027:Light; D009216:Myopia / Q000503:physiopathology*; D055095:Optics and Photonics; D009929:Organ Size; D012029:Refraction, Ocular; D012542:Scattering, Radiation
chemical_list: D003459:Crystallins