title: [Structure of poly(dA).poly(dT) from data of x-ray diffraction, energy calculations and nuclear magnetic resonance].
abstract: The results of X-ray diffraction studies of poly(dA).poly(dT) have been compared with the results of energy optimization and with the NMR data in solution. Slight refinement of the X-ray and energetically optimal models leads to a very good quantitative agreement with the NMR data, that suggests similarity of the poly(dA).poly(dT) structure in a condensed state and in solution. One of the features distinguishing these models from the classic B form is a narrowed minor groove of the double helix. The anomalous properties of DNA with this sequence can be related specific organization of the water molecules near the polynucleotide.
authors.forename: A A
authors.initials: AA
authors.lastname: Lipanov
authors.forename: I Ia
authors.initials: IIa
authors.lastname: Skuratovskiĭ
authors.forename: V I
authors.initials: VI
authors.lastname: Poltev
authors.forename: A G
authors.initials: AG
authors.lastname: Golovinskaia
authors.forename: V P
authors.initials: VP
authors.lastname: Chuprina
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011067:Poly dA-dT / Q000032:analysis*; D011089:Polydeoxyribonucleotides / Q000032:analysis*; D014961:X-Ray Diffraction
chemical_list: D011089:Polydeoxyribonucleotides; D011067:Poly dA-dT
vernacular_title: Struktura poli(dA).poli(dT) po dannym rentgenovskoĭ difraktsii, énergeticheskikh rashetov i iadernogo magnitnogo rezonansa.