title: Specific immunotherapy in hay fever.
abstract: The observation included 120 patients suffering from hay fever (HF) in age 18-58. In 77 of them specific immunotherapy (SI) with pollen vaccine was applicated through 3 consecutive years, while 43 patients remained without this form of therapy, as a control group. SI was efficient in 47% of treated patients, and in these cases IgE value came back to normal value, the IgG level increased and suppression of skin test to pollen allergens was observed. In 17% of treated patients side effects appeared during SI and together with exacerbation of HF, an increase of skin reaction to pollen allergens was noted.
authors.forename: K
authors.initials: K
authors.lastname: Obtulowicz
authors.forename: E
authors.initials: E
authors.lastname: Sanokowska
authors.forename: J
authors.initials: J
authors.lastname: Radwan
mesh_terms: D000293:Adolescent; D000328:Adult; D003176:Complement C3 / Q000032:analysis; D015932:Complement C3c; D003181:Complement C4 / Q000032:analysis; D003888:Desensitization, Immunologic; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D008875:Middle Aged; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D012397:Rosette Formation; D012882:Skin Tests
chemical_list: D003176:Complement C3; D003181:Complement C4; D007070:Immunoglobulin A; D007073:Immunoglobulin E; D015932:Complement C3c