Genetic risk and recombination fraction--an example of non-monotonic dependency.
The carrier risk for a monogenic disease is not generally monotonously dependent on the recombination fraction between the disease locus and a single marker locus.
Krawczak
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D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008957:Models, Genetic; D009136:Muscular Dystrophies / Q000235:genetics; D010375:Pedigree; D011995:Recombination, Genetic; D012306:Risk; D014960:X Chromosome
D005819:Genetic Markers