title: Reducing the man-machine barrier: the Sequence Analysis Workbench.
abstract: The conventional software paradigm in which the machine acts as an unintelligent but patient servant often increases the perceived distance between scientist and data. Direct manipulation offers an alternative paradigm in which the scientist uses the computer as a scientific instrument for examining and modifying the data directly, rather than by issuing instructions to an agent. The Sequence Analysis Workbench provides several experimental tools for direct manipulation of sequence data; object-oriented programming makes it possible to construct sophisticated tools quickly, and facilitates critical examination and review of scientific software.
authors.affiliation: E.I. du Pont de Nemours & Co. Inc., Wilmington, DE 19898.
authors.forename: M
authors.initials: M
authors.lastname: Bernstein
mesh_terms: D001483:Base Sequence; D004247:DNA; D012984:Software; D014584:User-Computer Interface
chemical_list: D004247:DNA