title: Bleeding duodenal ulcer--treatment strategy. A follow-up study.
abstract: In a follow-up study of 40 patients operated on for a bleeding vessel in a duodenal ulcer by means of ligation, pyloroplasty and vagotomy, we found that 9 patients (23%) suffered from recurrent bleeding, with a fatal outcome in 7 cases (78%). We conclude therefore that this method is unsuccessful, and if haemostasis is not achieved by endoscopic electrocoagulation operative resection is suggested. Where resection indicates too high a risk to the patient, we suggest that the operative procedure is reduced to ligation of the bleeding vessel combined with a medical vagotomy in the form of an H2-receptor antagonist.
authors.affiliation: Department of Surgery, Sundby Hospital, Copenhagen, Denmark.
authors.forename: H J
authors.initials: HJ
authors.lastname: Gyrtrup
authors.forename: T
authors.initials: T
authors.lastname: Orsnaes
authors.forename: J O
authors.initials: JO
authors.lastname: Søndergaard
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004381:Duodenal Ulcer / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology; D012008:Recurrence; D012086:Reoperation