title: Degradation kinetics of imipenem in normal saline and in human serum.
abstract: The stability of imipenem in 0.9% sodium chloride and in human serum was measured at controlled temperatures over time. The degradation was characterized by a first-order process and was consistent with an apparent hydrolysis reaction.
authors.forename: D J
authors.initials: DJ
authors.lastname: Swanson
authors.forename: C
authors.initials: C
authors.lastname: DeAngelis
authors.forename: I L
authors.initials: IL
authors.lastname: Smith
authors.forename: J J
authors.initials: JJ
authors.lastname: Schentag
mesh_terms: D004355:Drug Stability; D006207:Half-Life; D006801:Humans; D015378:Imipenem; D007700:Kinetics; D012965:Sodium Chloride; D013696:Temperature; D013845:Thienamycins / Q000032:analysis / Q000097:blood*
chemical_list: D013845:Thienamycins; D012965:Sodium Chloride; D015378:Imipenem