Airway hyperreactivity and menstrual cycle in asthmatic patients.
Healthy women and infertile asthmatic patients do not show any change in IgE, circulating eosinophils, sensitivity to metacholine, lung volumes. Allergic asthmatic patients tested in periods without allergen load and drug intake showed contrasting cycle related changes in aspecific hyperreactivity. Such changes are not directly related to hormonal levels. Circulating mediators are likely to explain observed pathways.
Valerio
G
G
Divisione di Fisiopatologia Respiratoria, Policlinico di Bari, Italy.
Lella
A
A
Fanizza
G
G
Barbanente
P
P
Attimonelli
R
R
Carnimeo
N
N
D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D001985:Bronchial Provocation Tests; D005260:Female; D012739:Gonadal Steroid Hormones / Q000502:physiology; D006801:Humans; D008597:Menstrual Cycle; D012137:Respiratory System / Q000503:physiopathology*
D012739:Gonadal Steroid Hormones