Clinical efficacy, safety and tolerability of intramuscular imipenem/cilastatin in the treatment of mild to moderate infections.
Intramuscular imipenem/cilastatin gave satisfactory results in 20 episodes of infection, which included 16 UTIs (five with bacteraemia). The preparation was well tolerated locally and systemically.
Garau
J
J
Casagrán
A
A
Sánchez
C
C
Matas
E
E
D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D015377:Cilastatin; D003521:Cyclopropanes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004150:Dipeptidases / Q000037:antagonists & inhibitors*; D005260:Female; D006801:Humans; D015378:Imipenem; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D013845:Thienamycins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D003521:Cyclopropanes; D013845:Thienamycins; D015377:Cilastatin; D015378:Imipenem; D004150:Dipeptidases