title: Morphometric study of cartilage dynamics in the chick embryo tibia. II. Dexamethasone-treated embryos.
abstract: The cartilage dynamics in the tibia of dexamethasone-treated chick embryos has been studied by means of morphometric methods. Treated embryos showed a delay in the longitudinal growth of the tibia, as well as in the growth of all structures enclosed by the perichondrium-periosteum. The cartilage formation rate remained nearly unchanged (above 1 mm3/day) from Day 12 to Day 14, whereas the cartilage resorption rate was zero up to Day 13, and showed a non-significant increase from Day 13 onwards. This might be related to the scarcity of resorptive cells found in the cartilage-marrow interface. By Day 14 a certain recovery of the growth rhythm was observed. These results indicate that the greatest effect of dexamethasone occurs at the level of cartilage resorption.
authors.affiliation: Department of Anatomy, School of Medicine, University of Córdoba, Spain.
authors.forename: F B
authors.initials: FB
authors.lastname: Ranz
authors.forename: J
authors.initials: J
authors.lastname: Aceitero
authors.forename: F
authors.initials: F
authors.lastname: Gaytan
mesh_terms: D000818:Animals; D001699:Biometry; D002356:Cartilage / Q000196:embryology*; D002642:Chick Embryo; D003907:Dexamethasone / Q000494:pharmacology*; D006132:Growth Plate / Q000187:drug effects / Q000196:embryology; D013977:Tibia / Q000196:embryology
chemical_list: D003907:Dexamethasone