t(Y;18) in acute myeloblastic leukemia FAB type M2.
Changes affecting the Y chromosome in neoplasia have been documented. However, this usually occurs as a loss of the Y chromosome in the affected cells accompanied by or preceding other karyotypic changes. Involvement of the Y chromosome in a translocation is extremely rare, there being only 14 cases reported in the literature. Presented here is a case of t(Y;18) in acute myeloblastic leukemia type M2 (FAB).
Jani Sait
S N
SN
Dal Cin
P
P
Sandberg
A A
AA
D000328:Adult; D002871:Chromosome Banding; D002902:Chromosomes, Human, 16-18; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic; D014998:Y Chromosome