Histocompatibility antigens (HLA-A, B) and ulcerative colitis in a Greek population.
Histocompatibility antigens (HLA-A, B) have been studied in 70 patients with ulcerative colitis of Greek origin. An increased frequency of HLA-A11, B7 and B13 (RR 2.1, 2.0 and 4.5, respectively) and a decreased frequency of HLA-B14 (RR 0.2) were found. Severe course of the disease was associated mainly with HLA-B13 (RR 5.5) whereas extensive spread of the colitis was associated with HLA-A11 and B7 (RR 2.6 and 3.2). Late onset of the disease (greater than 30 years) was characterized by increased frequency of HLA-A11, B7 and B13.
Papasteriades
C
C
Spiliadis
C
C
Emmanouilidis
A
A
Papadimitriou
C
C
Economidou
J
J
Manousos
O
O
D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000235:genetics*; D004198:Disease Susceptibility; D005260:Female; D006115:Greece; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006801:Humans; D008297:Male; D008875:Middle Aged
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens