Transplacental hemorrhage associated with placental neoplasms.
We report a case of choriocarcinoma in situ arising from a term placenta in an otherwise normal pregnancy that resulted in fetal hydrops and intrauterine fetal death from chronic fetal-maternal hemorrhage (FMH). The clinical and pathologic features are described and compared with the few similar cases reported and with an additional placental choriocarcinoma found in our files. We also describe the clinical and pathologic observations of two chorangiomas that caused massive FMH and led to fetal death.
Santamaria
M
M
Department of Pathology, University of California, San Diego Medical Center 92103.
Benirschke
K
K
Carpenter
P M
PM
Baldwin
V J
VJ
Pritchard
J A
JA
D000328:Adult; D002822:Choriocarcinoma / Q000150:complications / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005331:Fetomaternal Transfusion / Q000209:etiology*; D006391:Hemangioma / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D009336:Necrosis; D010920:Placenta / Q000473:pathology; D010922:Placenta Diseases / Q000150:complications / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*