Demonstrated paternity in spite of severe idiopathic oligospermia.
In this study we report on a successful pregnancy in the spouse of a man who, on repeated occasions, spaced over 3 years, presented with a mean sperm concentration of less than 200,000 sperm/ml. Serum was drawn from the father, mother, and daughter for polymorphic gene marker analysis. The calculation of relative probability of paternity with the use of gene frequencies for whites gave a figure of 99.9% that our patient is the father of the child.
Sokol
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Sparkes
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D000328:Adult; D002908:Chronic Disease; D002996:Clomiphene / Q000627:therapeutic use; D005819:Genetic Markers; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D010334:Paternity; D011110:Polymorphism, Genetic; D011336:Probability; D013076:Sperm Count / Q000187:drug effects
D005819:Genetic Markers; D002996:Clomiphene