Cytogenetic investigations in Hodgkin's disease: I. Involvement of specific chromosomes in marker formation.
Cytogenetic studies were performed in five Hodgkin-derived permanently growing cell lines, as well as in bone marrow cells from two Hodgkin patients, one of which suffering from acute myeloid leukemia after Hodgkin's disease. No consistent and common marker chromosome was found, but certain chromosome regions seemed to be nonrandomly involved in marker formation. These are chromosome bands 7q22, 7q32, 7q36, 2q33, 1p22, 11q21/23, 14q32, 15p12, and 21q21. The importance and significance of these chromosomal findings are discussed in reference to data from the literature.
Fonatsch
C
C
Diehl
V
V
Schaadt
M
M
Burrichter
H
H
Kirchner
H H
HH
D002869:Chromosome Aberrations; D002906:Chromosomes, Human, 6-12 and X; D005819:Genetic Markers; D006689:Hodgkin Disease / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D014178:Translocation, Genetic
D005819:Genetic Markers