The effect of oxalic acid on the aggregability of human platelet rich plasma.
Human platelet aggregation induced by ADP was studied after incubation with urea, methylguanidine, creatinine and oxalic acid. Oxalic acid significantly (p less than 0.05) inhibits human thrombocyte aggregation. Physiopathological implications are discussed.
Camici
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Evangelisti
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Raspolli-Galletti
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D000244:Adenosine Diphosphate / Q000494:pharmacology; D000293:Adolescent; D003404:Creatinine / Q000494:pharmacology; D006801:Humans; D008760:Methylguanidine / Q000494:pharmacology; D010070:Oxalates / Q000494:pharmacology*; D019815:Oxalic Acid; D010974:Platelet Aggregation / Q000187:drug effects*; D014508:Urea / Q000494:pharmacology; D014511:Uremia / Q000097:blood
D010070:Oxalates; D008760:Methylguanidine; D000244:Adenosine Diphosphate; D014508:Urea; D019815:Oxalic Acid; D003404:Creatinine