[Antibody-dependent cytotoxicity of lymphocytes in acute myeloblastic leukemia and chronic myelocytic leukemia].
Antibody-dependent cytotoxicity (ADC) of peripheral blood blast cells in vitro was studied in 16 patients with acute myeloid leukemia (AML), 6 patients with acute monoblastic leukemia (AMonL), and 13 patients with acute myelomonoblastic leukemia (AMmL). It was found that monoblasts have a higher degree of ADC activities with respect to target cells than myeloblasts. Functional differences between monoblasts and myeloblasts may be used as criteria for differential diagnosis of acute leukemia variants.
Tishchenko
L M
LM
Guseva
S A
SA
D000328:Adult; D000920:Antibody-Dependent Cell Cytotoxicity; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000276:immunology*; D015470:Leukemia, Myeloid, Acute / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged
Antitelozavisimaia tsitotoksichnost' limfotsitov pri ostrom mieloblastnom leĭkoze i khronicheskom mieloleĭkoze.