title: Trisomy 9 in hematologic disorders: possible association with primary thrombocytosis.
abstract: Ten patients with a hematologic disorder and a clone of cells with trisomy 9 in the bone marrow were studied in order to investigate the clinical significance of this chromosome anomaly. In five of the patients, trisomy 9 was the only anomaly; in four, there was also trisomy 8; and in one, a Y chromosome was also lacking. Four patients had a myelodysplastic syndrome, and six had a myeloproliferative disorder. Interestingly, four patients had primary thrombocytosis.
authors.forename: D
authors.initials: D
authors.lastname: Cournoyer
authors.forename: P
authors.initials: P
authors.lastname: Noël
authors.forename: M A
authors.initials: MA
authors.lastname: Schmidt
authors.forename: G W
authors.initials: GW
authors.lastname: Dewald
mesh_terms: D000328:Adult; D000368:Aged; D002871:Chromosome Banding; D002899:Chromosomes, Human, Pair 9; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D009196:Myeloproliferative Disorders / Q000235:genetics*; D013922:Thrombocytosis / Q000235:genetics*; D014314:Trisomy
chemical_list: D005819:Genetic Markers