Is arterial blood pressure a powerful factor in sodium excretion?
The control of sodium balance is very complex. Many different factors act together in the regulation of renal sodium excretion. Some investigators suggest that arterial blood pressure has a direct effect on urinary excretion of sodium and water. They report that whenever arterial pressure increases, urinary excretion of sodium and water also increases. This phenomenon is called pressure diuresis and natriuresis. It has been stated that an increase in arterial pressure of about 30% can increase urinary output as much as three-fold or more. Many studies, especially in the isolated, perfused kidney, support this idea. However, it is not clear how important this mechanism is under physiological conditions.
Palm
U
U
Arbeitsgruppe Experimentelle Anästhesie, Klinikum Charlottenburg, Freie Universität Berlin.
Reinhardt
H W
HW
Hey
A
A
Mohnhaupt
R
R
D000818:Animals; D001794:Blood Pressure; D004231:Diuresis; D004285:Dogs; D005260:Female; D009318:Natriuresis; D012982:Sodium, Dietary / Q000008:administration & dosage
D012982:Sodium, Dietary