title: [Pyoderma gangrenosum and hemopathies. Apropos of 2 cases].
abstract: Pyoderma gangrenosum (PG) is an uncommon ulcerative disease of the skin. The cause is unknown but the condition is often associated with other diseases such as rheumatoid arthritis, ulcerative colitis, Crohn's disease or monoclonal gammopathy. The association between PG and haematological malignancies (acute leukaemia, Myeloproliferative disorders) is infrequent. Two cases of PG associated with haemopathy are described; one had primary thrombocythaemia and the other, acute myeloblastic leukaemia following for myeloma. The significance of this association is discussed in the light of other observations previously reported in the literature.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D011711:Pyoderma / Q000150:complications* / Q000188:drug therapy; D013792:Thalidomide / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000150:complications*
chemical_list: D000305:Adrenal Cortex Hormones; D013792:Thalidomide
vernacular_title: Pyoderma gangrenosum et hémopathies. A propos de 2 observations.