title: [Thrombocyte functions in malignant blood diseases].
abstract: Platelet aggregation with various inductors and platelet secretion were studied in chronic lymphoid leukemia, myeloma, chronic myeloid leukemia and acute leukemia. It was established that disturbed aggregation with adrenaline and disturbed secretion are found more often in these malignant blood diseases. An interesting fact is that there is no correlation between the disturbed platelet functions in vitro and the clinical manifestations of disturbed hemostasis (hemorrhages or thrombosis).
mesh_terms: D000208:Acute Disease; D000244:Adenosine Diphosphate / Q000494:pharmacology; D001792:Blood Platelets / Q000502:physiology*; D004837:Epinephrine / Q000494:pharmacology; D006487:Hemostasis; D006801:Humans; D007938:Leukemia / Q000097:blood*; D007945:Leukemia, Lymphoid / Q000097:blood; D007951:Leukemia, Myeloid / Q000097:blood; D009101:Multiple Myeloma / Q000097:blood; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count
chemical_list: D000244:Adenosine Diphosphate; D004837:Epinephrine
vernacular_title: Prouchvane na trombotsitnite funktsii pri niakoi zlokachestveni krŭvni zaboliavaniia.