title: [Septic endocarditis--a predictable or unpredictable disease? Clinico-immunologic aspects].
abstract: Based on an analysis of the clinical picture of 248 cases of septic endocarditis, disorders in the immunologic status (reduction in the E-RFC, EAC-RFC counts, absolute count of Ea-RFC, significant rise of immunoglobulins of all classes, hypocomplementemia in 37.5% of patients, increase in the titer of circulating immune complexes in 86% of patients) the authors discuss the causes (virulence of the causative agent, immunodeficiency) that favour the development of septic endocarditis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D004697:Endocarditis, Bacterial / Q000209:etiology*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007108:Immune Tolerance; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008231:Lymphopenia / Q000150:complications*; D008875:Middle Aged; D012397:Rosette Formation; D013203:Staphylococcal Infections / Q000209:etiology*; D013290:Streptococcal Infections / Q000209:etiology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Septicheskiĭ endokardit--predugotovannoe ili nepredskazuemoe zabolevanie? Kliniko-immunologicheskie aspekty.