title: [Clinical evaluation of ofloxacin against complicated urinary tract infections].
abstract: Clinical efficacy of ofloxacin (OFLX) against complicated urinary tract infections was examined in 20 patients. OFLX was administrated orally at a dose of 200 mg, three times (daily 600 mg) for 14 to 102 days. The overall clinical efficacy was rated excellent in 8 cases (40%), moderate in 7 cases (35%) and poor in 5 cases (25%) with a total efficacy of 75%. Bacteriological efficacy, 17 out of 24 strains (70.8%) isolated were eradicated after OFLX administration. The strains that appeared after OFLX treatment were P. cepacia and Candida sp. No severe side effects were found in these patients.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin; D010078:Oxazines / Q000008:administration & dosage / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000892:Anti-Infective Agents, Urinary; D010078:Oxazines; D015242:Ofloxacin