title: Plasmid-to-chromosome gene transfer in Haemophilus influenza during growth.
abstract: A low level of recombination between homologous regions of plasmids and the host chromosome occurred during cell growth. The plasmids contained antibiotic resistance markers on the homologous regions which were only expressed when they were integrated into the chromosome. Such recombination took place in Rec+ rec-2 mutants but not in rec-1 mutants.
mesh_terms: D002701:Chloramphenicol / Q000494:pharmacology; D002876:Chromosomes, Bacterial; D004352:Drug Resistance, Microbial; D005798:Genes, Bacterial; D006193:Haemophilus influenzae / Q000187:drug effects / Q000235:genetics* / Q000254:growth & development; D009154:Mutation; D009675:Novobiocin / Q000494:pharmacology; D010957:Plasmids; D011995:Recombination, Genetic
chemical_list: D009675:Novobiocin; D002701:Chloramphenicol