Sister chromatid exchange in immature haemopoietic cells, T- and B-lymphocytes.
T-lymphocytes, B-lymphocytes, and cells derived from human haemopoietic progenitor cells were analysed for their sister chromatid exchange (SCE) rate. T- and B-lymphocytes were separated and stimulated with phytohaemagglutinin (PHA) and Epstein Barr (EB) virus respectively, while the progenitor cells were cultured in the mixed colony assay. B-lymphocytes had a significantly lower SCE rate than either the T-lymphocytes or cells derived from progenitor cells.
D001402:B-Lymphocytes / Q000648:ultrastructure*; D005312:Fetal Blood; D006412:Hematopoietic Stem Cells / Q000648:ultrastructure*; D006801:Humans; D007231:Infant, Newborn; D012854:Sister Chromatid Exchange; D013601:T-Lymphocytes / Q000648:ultrastructure*