title: [Immunological study of the T- and B-lymphocytes in normal cows and in chronic lympholeukemia].
abstract: T- and B-lymphocyte populations from lymphoid organs and tissue of normal cattle and cattle with chronic lymphocytic leukaemia (CLL) were studied. Comparative studies of surface properties, quantitative parameters and heterogeneity of main T- and B-cell populations were performed. It must be noted that proliferation of B-lymphocytes, bearing surface IgM in blood, lymph nodes and spleen is closely connected with the progression of leukaemic process. An increased number of B-lymphocytes (2-3 times) with the receptors for complement was found. The proportion of T mu and T gamma cell subsets in CLL cows is distorted. The T gamma cell subset in T-cell suspensions from blood and spleen in CLL cows prevails in comparison with that in controls. The number of T mu cells in blood and lymph nodes in CLL is decreased.
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D002417:Cattle / Q000276:immunology*; D002418:Cattle Diseases / Q000276:immunology*; D005260:Female; D007945:Leukemia, Lymphoid / Q000276:immunology / Q000662:veterinary*; D007958:Leukocyte Count / Q000662:veterinary; D008221:Lymphoid Tissue / Q000276:immunology; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D011947:Receptors, Antigen, B-Cell
vernacular_title: Immunologicheskoe izuchenie T- i B-limfotsitov u korov v norme i pri khronicheskom limfoleĭkoze.