Modification of the T, K and NK cell population in experimental infection of mice with Aspergillus niger.
A study has been made of the cellular response by T, K and NK cells in mice experimentally infected with Aspergillus niger. The tests were made on mice treated with 5 X 10(5) conidia. The lymphocyte populations in the blood, spleen and pulmonary lymphnodes have studied to identify possible modifications in immune response in time. The results obtained show that in experimentally infected mice with respect to uninfected mice there is an increase in T-lymphocytes, particularly in the spleen, a percentage increase in EA-RFC cells in the blood, spleen and lymphnodes, a percentage increase in LGL cells, with a rise in associated NK activity, in the blood and spleen in the first days of infection, but a delayed increase in the lymphnodes.
D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D001228:Aspergillosis / Q000276:immunology*; D001234:Aspergillus niger; D007694:Killer Cells, Natural / Q000276:immunology*; D007958:Leukocyte Count; D008198:Lymph Nodes / Q000276:immunology; D051379:Mice; D012397:Rosette Formation; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*