Regional localization of a human cytochrome P-450 (CYP1) to chromosome 19q13.1-13.3.
A phenobarbitone inducible cytochrome P-450 gene family (CYP1) has recently been localized to chromosome 19q13.1-qter. We have used a human liver cDNA probe in in situ hybridization experiments to metaphase chromosomes from two balanced translocation carriers, 46,XX,t(11;19) (q13;q13.1) and 46,XX,t(7;19) (q31.3;q13.3) to obtain a more precise localization. The results suggest a regional assignment for CYP1 to chromosome 19q13.1-13.3.
D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D005819:Genetic Markers; D006801:Humans; D009693:Nucleic Acid Hybridization
D005819:Genetic Markers; D003577:Cytochrome P-450 Enzyme System