An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen.
Thymocytes of CD4-,CD8+,OX-44- phenotype have been shown to be an intermediate of thymopoiesis that give rise to cells of CD4+, CD8+, OX-44- normal cortical thymocyte phenotype both in vitro and in vivo during thymic regeneration.
D000818:Animals; D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte / Q000031:analogs & derivatives / Q000235:genetics*; D002454:Cell Differentiation; D002455:Cell Division; D005786:Gene Expression Regulation; D006410:Hematopoiesis; D006649:Histocompatibility Antigens / Q000235:genetics; D010641:Phenotype; D051381:Rats; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*; D060265:Tetraspanin 25
D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D006649:Histocompatibility Antigens; D060265:Tetraspanin 25