Effect of milk protein and fat intake on blood pressure and the incidence of cerebrovascular diseases in stroke-prone spontaneously hypertensive rats (SHRSP).
The intake of two milk protein-rich diets containing casein and whey protein attenuated the development of severe hypertension in stroke-prone spontaneously hypertensive rats (SHRSP), and extended their life span in comparison with SHRSP on a regular stock diet. Milk fat-rich diet intake reduced the incidence of cerebrovascular disease in SHRSP without a significant fall in blood pressure. These results suggest that certain milk components have a preventive effect on hypertension and cerebrovascular disease in SHRSP.
D000818:Animals; D002364:Caseins / Q000008:administration & dosage; D002561:Cerebrovascular Disorders / Q000517:prevention & control*; D004041:Dietary Fats / Q000008:administration & dosage / Q000494:pharmacology*; D004044:Dietary Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D006973:Hypertension / Q000517:prevention & control*; D007785:Lactose / Q000008:administration & dosage; D008894:Milk Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011918:Rats, Inbred SHR; D011922:Rats, Mutant Strains
D002364:Caseins; D004041:Dietary Fats; D004044:Dietary Proteins; D008894:Milk Proteins; D007785:Lactose