[Effect of the C1q complement subcomponent on blood coagulability and fibrinolysis].
The in vitro experiments on human plasma have shown that C1q addition in a concentration of 120 micrograms/ml led to a substantial shortening of coagulation time of test-plasma, as well as kaolin- and cephalin time. The effect is preserved in plasma deficient in factors V, X and VII. It is assumed that C1q has properties similar to those of thromboplastin.
D001777:Blood Coagulation / Q000187:drug effects*; D003166:Complement Activating Enzymes / Q000494:pharmacology*; D015922:Complement C1q; D004305:Dose-Response Relationship, Drug; D005166:Factor V Deficiency / Q000097:blood; D005168:Factor VII Deficiency / Q000097:blood; D005171:Factor X Deficiency / Q000097:blood; D005342:Fibrinolysis / Q000187:drug effects*; D006801:Humans
D015922:Complement C1q; D003166:Complement Activating Enzymes
Vliianie C1q subkomponenta komplementa na sverytaenost' krovi i fibrinoliz.