In vitro susceptibility of 96 Capnocytophaga strains, including a beta-lactamase producer, to new beta-lactam antibiotics and six quinolones.
The in vitro activities of new beta-lactam antibiotics and new quinolones were studied against 96 Capnocytophaga strains, including a beta-lactamase-producing strain which was resistant to ampicillin, amoxicillin, carbenicillin, cephalothin, and cefamandole. All strains were susceptible to the combination of amoxicillin and clavulanic acid, ureidopenicillins, cefoxitin, broad-spectrum cephalosporins, and imipenem. Cephalothin and cefamandole did not show good activity against most strains. All Capnocytophaga spp. were uniformly susceptible to the five new quinolones tested.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002206:Capnocytophaga / Q000187:drug effects* / Q000201:enzymology; D041964:Cytophagaceae / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D011804:Quinolines / Q000494:pharmacology*; D001618:beta-Lactamases / Q000096:biosynthesis*; D047090:beta-Lactams
D000900:Anti-Bacterial Agents; D011804:Quinolines; D047090:beta-Lactams; D001618:beta-Lactamases