title: The relative potencies of thiopentone and propofol.
abstract: The relative potencies of the intravenous anaesthetics propofol and thiopentone have been investigated by finding the dose necessary to produce unconsciousness in approximately 30%, 50% and 80% of patients. The estimated potency of propofol to thiopentone was 1:1.604 as obtained by the probit method of analysis which estimates the logarithm of the relative potency.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation / Q000379:methods; D006801:Humans; D008875:Middle Aged; D010636:Phenols / Q000008:administration & dosage; D015742:Propofol; D013223:Statistics as Topic; D013874:Thiopental / Q000008:administration & dosage
chemical_list: D010636:Phenols; D013874:Thiopental; D015742:Propofol