title: [Immunological effectiveness of a 2d revaccination against diphtheria performed at intervals extended up to 7-10 years].
abstract: The present article deals with the data on the duration of antidiphtheria immunity, induced by the primary cycle of immunization with adsorbed DPT vaccine, with the aim of considering the problems of optimizing the immunization schedule for children. The prolongation of the interval before the second booster immunization to 7-10 years produces no negative influence on the effectiveness of immunization. Besides, the study has shown that after the main complex of immunizations with adsorbed DPT vaccine protective immunity to diphtheria is retained in 90.3-96.8% of children covered by this study for 9-10 years. These data point to high immunological effectiveness of adsorbed DPT vaccine and to the possibility of prolonging the intervals between booster immunizations to 10 years, as well as decreasing the number of booster immunizations in the immunization schedule for children.
mesh_terms: D000293:Adolescent; D002648:Child; D004165:Diphtheria / Q000276:immunology / Q000517:prevention & control; D004166:Diphtheria Antitoxin / Q000032:analysis; D004168:Diphtheria Toxoid / Q000276:immunology*; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations / Q000276:immunology; D006801:Humans; D007109:Immunity; D007114:Immunization; D007117:Immunization, Secondary; D009031:Moscow; D010567:Pertussis Vaccine / Q000276:immunology*; D013745:Tetanus Toxoid / Q000276:immunology*; D013997:Time Factors
chemical_list: D004166:Diphtheria Antitoxin; D004168:Diphtheria Toxoid; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D004338:Drug Combinations; D010567:Pertussis Vaccine; D013745:Tetanus Toxoid
vernacular_title: Immunologicheskaia éffektivnost' vtoroĭ revaktsinatsii protiv difterii, provedennoĭ s intervalami, udlinennymi do 7--10 let.