Long term management of hemorrhagic esophagitis with cimetidine and omeprazole.
We report a patient whose severe recurrent anemia was due to overt and occult hemorrhage from peptic esophagitis. Cimetidine treatment was successful for seven years but dose reduction was followed by intractable hemorrhage which did not respond to H2-receptor antagonists. Omeprazole therapy produced dramatic remission of symptoms and anemia.
D000740:Anemia / Q000209:etiology; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D002927:Cimetidine / Q000627:therapeutic use*; D004941:Esophagitis / Q000150:complications / Q000188:drug therapy*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole
D000897:Anti-Ulcer Agents; D001562:Benzimidazoles; D002927:Cimetidine; D009853:Omeprazole