Polygraphic monitoring in prevention of ischaemic brain damage during surgery and intensive care.
The investigations described show: Firstly, the EEG concomitants of cerebral ischaemia are quantitatively related to the extent of subsequent infarction. Secondly, their time sequence can be characterised by relatively simple measures such as continuous display of amplitude variability (including clear indication of even very brief periods of electrocerebral silence) of the EEG filtered to emphasize the alpha and beta frequency bands. Addition of information about frequency distribution helps differentiate between effects of ischaemia and of anaesthesia. Thirdly, there is considerable potential value in the routine clinical use of such techniques to prevent ischaemic brain damage. The arguments for routine clinical monitoring are based on the cited correlative studies between EEG and clinical or neuropathological outcome and on follow-up studies as to the effect of intervention based on neurophysiological warning signs on clinical outcome (e.g., Kriticou and Branthwaite 1977).
D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D002545:Brain Ischemia / Q000517:prevention & control*; D003128:Coma / Q000503:physiopathology; D003422:Critical Care / Q000379:methods*; D004569:Electroencephalography; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D008991:Monitoring, Physiologic