[The use of levamisole (decaris) in patients with inoperable lung cancer].
Immunologic vigor and the efficacy of combined treatment (short- and long-term courses of levamisole + chemoradiotherapy) were assessed in 195 cases of inoperable epidermoid cancer of the lung. In some cases, lymphocyte response to levamisole in vitro incubation was studied in a reaction of spontaneous rosette formation with ovine erythrocytes prior to therapy. Shorter courses of levamisole used in combination with chemoradiotherapy were followed, on the average, by a 4 months longer survival. The results obtained make the case for studying lymphocyte response to levamisole in vitro in a reaction of spontaneous rosette formation as a criterion for its administration for lung cancer treatment.
D003131:Combined Modality Therapy; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000401:mortality / Q000532:radiotherapy; D012397:Rosette Formation; D012882:Skin Tests; D013601:T-Lymphocytes / Q000276:immunology
D007978:Levamisole
Ispol'zovanie levamizola (dekarisa) u neoperabel'nykh bol'nykh rakom legkogo.