title: Incidental finding of double minutes (DM), single minutes (SM), homogenously staining regions (HSR), premature chromosome condensation (PCC), and premature centromere division (PCD)?
abstract: The incidental finding of DM's, minutes, HSR's, PCC, and PCD in two completely unrelated cases--one is a prenatal diagnosis in a twin pregnancy complicated by hydramnios and feto-fetal exsanguination, the other is an adult Klinefelter patient--raises the question whether such findings are coincidental or whether there is a common denominator in such cases. Possible relationships between these phenomena and the observed cases are discussed.
mesh_terms: D000328:Adult; D002478:Cells, Cultured; D002503:Centromere / Q000648:ultrastructure*; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002875:Chromosomes / Q000648:ultrastructure*; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000235:genetics*; D008214:Lymphocytes / Q000166:cytology; D008297:Male; D008875:Middle Aged; D008938:Mitosis; D011247:Pregnancy; D014427:Twins; D014429:Twins, Dizygotic