title: Extended wear of contact lenses can compromise corneal epithelial adhesion.
abstract: The wound healing response of the cat corneal epithelium was examined to provide information on the effect of extended wear contact lenses on epithelial integrity. During the wounding procedure, a loss of epithelial adhesion in the lens wearing eye relative to the control eye was noted. This indicates a loss of epithelium-to-basement membrane adhesion which may be a result of contact-lens induced hypoxia.
mesh_terms: D000818:Animals; D002415:Cats; D003262:Contact Lenses, Extended-Wear / Q000009:adverse effects*; D003263:Contact Lenses, Hydrophilic / Q000009:adverse effects*; D003315:Cornea / Q000502:physiology*; D004848:Epithelium / Q000502:physiology; D014945:Wound Healing