Three-dimensional structure of interleukin-2.
Interleukin-2 is an effector protein that participates in modulating the immune response; it has become a focal point for the study of lymphokine structure and function. The three-dimensional structure of the interleukin molecule has been solved to 3.0 angstrom resolution. Interleukin-2 has a novel alpha-helical tertiary structure that suggests one portion of the molecule forms a structural scaffold, which underlies the receptor binding facets of the molecule.
D000818:Animals; D007376:Interleukin-2 / Q000302:isolation & purification; D051379:Mice; D008958:Models, Molecular; D011487:Protein Conformation; D012997:Solvents; D014961:X-Ray Diffraction
D007376:Interleukin-2; D012997:Solvents