Killing of Friend erythroleukaemia cells by cytochalasin B is cell cycle specific.
Exposure to 2.0 micrograms/ml cytochalasin B causes loss of viability in Friend erythroleukaemia cells. This effect is only observed however in cells undergoing mitosis.
D000818:Animals; D002453:Cell Cycle; D002460:Cell Line; D002467:Cell Nucleus / Q000187:drug effects; D003571:Cytochalasin B / Q000494:pharmacology*; D005622:Friend murine leukemia virus; D006118:Griseofulvin / Q000494:pharmacology; D004915:Leukemia, Erythroblastic, Acute / Q000473:pathology*; D051379:Mice; D011123:Polyploidy; D014407:Tumor Cells, Cultured / Q000187:drug effects* / Q000648:ultrastructure; D014410:Tumor Stem Cell Assay
D006118:Griseofulvin; D003571:Cytochalasin B