Serum protein polymorphisms in a Liberian population.
Serum protein variations were studied in a Liberian population living in Buchanan town. Of the alpha 1-antitrypsin genes only M1 and M3 were polymorphic. The frequencies of the haptoglobin and Gc genes were in accordance with earlier known estimates in African populations. There was, however, a relatively low frequency of Hp 0 which may be related to the low malarial parasite prevalence in this group. The transferrin C2 gene was found in a significantly lower frequency among Liberians compared to European and Asiatic populations. A new transferrin variant was observed by isoelectric focusing. This variant could not be identified with conventional starch or polyacrylamide electrophoresis.
D001798:Blood Proteins / Q000235:genetics*; D005787:Gene Frequency; D006242:Haptoglobins / Q000235:genetics; D006801:Humans; D007988:Liberia; D011110:Polymorphism, Genetic; D014168:Transferrin / Q000235:genetics; D014809:Vitamin D-Binding Protein / Q000235:genetics; D000515:alpha 1-Antitrypsin / Q000235:genetics
D001798:Blood Proteins; D006242:Haptoglobins; D014168:Transferrin; D014809:Vitamin D-Binding Protein; D000515:alpha 1-Antitrypsin