title: Tissue response to retrograde root fillings in the ferret canine: a comparison of a glass ionomer cement and gutta-percha with sealer.
abstract: Tissue healing was compared after apicectomy and filling of ferret lower canines with glass ionomer (Ketacfil) or gutta-percha/sealer (Tubliseal). Both materials provoked an inflammatory response after 7 days, but the response to glass ionomer was less severe. The response after 28 days was different. Mild inflammation related to the gutta-percha was still present, but no inflammation was found in relation to the glass ionomer. Bone infill was quite advanced in all specimens at 28 days but was more complete in the glass ionomer specimens, with intimate contact between the bone and cement.
mesh_terms: D000818:Animals; D003738:Dental Cements / Q000009:adverse effects*; D005289:Ferrets; D005899:Glass Ionomer Cements / Q000009:adverse effects*; D006171:Gutta-Percha / Q000009:adverse effects*; D010485:Periapical Periodontitis / Q000139:chemically induced / Q000473:pathology*; D010486:Periapical Tissue / Q000187:drug effects / Q000473:pathology*; D012184:Retrograde Obturation; D012387:Root Canal Filling Materials / Q000009:adverse effects; D015035:Zinc Oxide-Eugenol Cement
chemical_list: D003738:Dental Cements; D005899:Glass Ionomer Cements; D012387:Root Canal Filling Materials; D015035:Zinc Oxide-Eugenol Cement; C048769:tubliseal; D006171:Gutta-Percha