Prostaglandin E2 vaginal suppository for induction of labour: an efficient, safe and popular method.
Two different methods for induction of labour were randomly used in 100 women with a favourable cervix. The patients were treated with either prostaglandin vaginal suppositories containing 2.5 mg PGE2 in a base of Witepsol S55 (Dynamit Nobel) or intravenous infusion of oxytocin. The PGE2 vaginal suppository was significantly more efficient than the intravenous infusion of oxytocin in relation to the time interval from the start of induction of labour to delivery. Also the percentage of women who delivered within 48 hours (success rate) was higher in the suppository group. Significantly more women in the suppository group found this induction method recommendable.
D015232:Dinoprostone; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007751:Labor, Induced / Q000379:methods*; D010120:Oxytocics; D010121:Oxytocin / Q000008:administration & dosage; D010570:Pessaries; D011247:Pregnancy; D011458:Prostaglandins E / Q000008:administration & dosage*
D010120:Oxytocics; D011458:Prostaglandins E; D010121:Oxytocin; D015232:Dinoprostone