title: Coagulation of aneurysms by direct percutaneous thrombin injection.
abstract: We describe a new technique for clotting aneurysms by direct injection of diluted thrombin through a fine needle or cannula. The four patients treated had pseudoaneurysms of the iliac, femoral, and peroneal arteries, and a true aneurysm of an accessory hepatic artery. Five hundred to one thousand (500-1000) units of thrombin were injected into the aneurysmal sac only when there was blood stasis, either de novo or induced by occlusion of the feeding vessel. No significant complications ensued.
mesh_terms: D000293:Adolescent; D000368:Aged; D000783:Aneurysm / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005263:Femoral Artery; D006499:Hepatic Artery; D006801:Humans; D007083:Iliac Artery; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D013917:Thrombin / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D013917:Thrombin