Extramedullary haemopoiesis in the small bowel.
A patient with myelofibrosis developed repeated gastrointestinal haemorrhage from the small intestine, which was found to be infiltrated with extramedullary haemopoiesis. Nineteen months later he presented with subacute intestinal obstruction; radiology and laparotomy documented progressive infiltration of the small bowel. Histological examination of the resected terminal ileum showed patchy mucosal ulceration, with underlying submucosal and serosal extramedullary haemopoiesis.
D006471:Gastrointestinal Hemorrhage / Q000150:complications* / Q000503:physiopathology; D006410:Hematopoiesis; D006801:Humans; D007077:Ileal Diseases / Q000150:complications; D007415:Intestinal Obstruction / Q000209:etiology; D007421:Intestine, Small / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000150:complications* / Q000503:physiopathology; D014456:Ulcer / Q000150:complications