title: The ultrastructure of human gingival Langerhans cells in health and disease.
abstract: There was a statistically significant shift towards increased proportions of type I Langerhans cells (containing many Langerhans-cell granules) and reduced proportions of both type II Langerhans cells (containing few granules) and indeterminate cells in diseased oral epithelium when compared to healthy oral epithelium. Langerhans cells and indeterminate cells were also seen in the sulcular epithelium of healthy and diseased specimens but never in junctional or pocket-lining epithelium.
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004848:Epithelium / Q000648:ultrastructure; D005881:Gingiva / Q000648:ultrastructure*; D006801:Humans; D007801:Langerhans Cells / Q000648:ultrastructure*; D008854:Microscopy, Electron; D010518:Periodontitis / Q000473:pathology*