title: Gastrointestinal side effects with erythromycin preparations.
abstract: This study was designed to determine the incidence and severity of gastrointestinal (GI) side effects in patients taking erythromycin. More patients complained of GI side effects with the enteric-coated tablet (70.8 percent) than with the stearate (51.4 percent) or the ethylsuccinate (48.9 percent) salts. The enteric-coated tablet was associated with a higher incidence of individual adverse reactions; more patients discontinued it because of adverse GI effects. These data demonstrate a high incidence of GI side effects to erythromycin. Additionally, GI side-effect incidence appears to be higher with the enteric-coated tablet.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004917:Erythromycin / Q000008:administration & dosage / Q000009:adverse effects* / Q000031:analogs & derivatives; D015643:Erythromycin Ethylsuccinate; D005767:Gastrointestinal Diseases / Q000139:chemically induced*; D006801:Humans; D008875:Middle Aged; D013608:Tablets, Enteric-Coated
chemical_list: D013608:Tablets, Enteric-Coated; D015643:Erythromycin Ethylsuccinate; D004917:Erythromycin; C011462:erythromycin stearate