title: Giant cell arteritis in two brothers.
abstract: Giant cell arteritis developed in 2 brothers nearly simultaneously. They were positive for HLA-DR4 tissue antigen which has been associated with this disease. Both genetic and environmental factors may be important in the development of giant cell arteritis.
mesh_terms: D000368:Aged; D013700:Giant Cell Arteritis / Q000235:genetics* / Q000276:immunology; D006680:HLA Antigens / Q000145:classification; D015804:HLA-DR4 Antigen; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D006801:Humans; D008297:Male; D011111:Polymyalgia Rheumatica / Q000235:genetics / Q000276:immunology
chemical_list: D006680:HLA Antigens; D015804:HLA-DR4 Antigen; D000949:Histocompatibility Antigens Class II