Flavonoids protect against T-2 mycotoxins both in vitro and in vivo.
Quercetin was able to reduce the cytotoxic effect of T-2 mycotoxin on cultured murine thymocytes. When given to mice immediately before challenge with T-2 mycotoxins, quercetin significantly reduced mortality.
D000818:Animals; D002170:Canada; D002478:Cells, Cultured; D003601:Cytotoxicity Tests, Immunologic; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000494:pharmacology*; D051379:Mice; D009183:Mycotoxins / Q000037:antagonists & inhibitors* / Q000633:toxicity; D011794:Quercetin / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000187:drug effects
D005419:Flavonoids; D009183:Mycotoxins; D011794:Quercetin