[Comparison of ampicillin, chloramphenicol and trimethoprim-sulfamethoxazole (TMP-SMZ) for the treatment of Salmonella typhi infections in clinical practice].
Ninety-four patients with Salmonella typhi infection hospitalized and treatment. Widal test results, blood cultures, stool cultures and physical examination findings were admitted infection criteria. Ampicillin used 100 mg/kg/day four divided dose in 52 patients, chloramphenicol used 2g/day four divided dose in 28 patients and TMP-SMZ 160-800 mg used bid in 14 patients. All of the treatments applied for 2 weeks. Ampicillin 92.30%, chloramphenicol 82.15% and TMP-SMZ 85.71% were found success. Fever dropped in normal degrees 3.43 +/- 1.71 days in ampicillin group, 3.47 +/- 1.13 days in chloramphenicol group and 3 +/- 1.41 days in TMP-SMZ group.
D000293:Adolescent; D000328:Adult; D000667:Ampicillin / Q000008:administration & dosage / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002701:Chloramphenicol / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004338:Drug Combinations / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013420:Sulfamethoxazole / Q000008:administration & dosage / Q000627:therapeutic use*; D014295:Trimethoprim / Q000008:administration & dosage / Q000627:therapeutic use*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014435:Typhoid Fever / Q000188:drug therapy*
D000890:Anti-Infective Agents; D004338:Drug Combinations; D002701:Chloramphenicol; D000667:Ampicillin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole
Salmonella typhi infeksiyonlarinin tedavisinde ampicillin, chloramphenicole ve trimethoprim-sulfamethoxazole (TMP-SMZ)'ün klinik uygulamada karşilaştirilmasi.