Immunological findings during treatment of multiple keratoacanthoma with etretinate.
Treatment with etretinate in a patient with multiple keratoacanthoma is described. Clinical improvement correlated with normalization of IL-2-production and mitogen induced lymphocyte proliferation. A causal relationship between reduced IL-2-production and eruption of keratoacanthoma is suggested.
D000368:Aged; D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis; D007636:Keratoacanthoma / Q000188:drug therapy / Q000276:immunology*; D008213:Lymphocyte Activation; D008934:Mitogens / Q000494:pharmacology; D013601:T-Lymphocytes / Q000145:classification
D007376:Interleukin-2; D008934:Mitogens; D005050:Etretinate