title: Effect of fluoride containing dentifrice, mouthrinsing, and varnish on approximal dental caries in a 3-year clinical trial.
abstract: The purpose of this study was to evaluate the separate effect of fluoride dentifrice, fluoride mouthrinsing and fluoride varnish on approximal dental caries. All 252 13-14-yr-old children at an elementary school were selected at random and divided among four groups for a 3-yr longitudinal study. Group 1 received a fluoride dentifrice for home care and a fluoride mouthrinse once a week. Group 2 received a fluoride dentifrice for home care and a placebo mouthrinse once a week. Group 3 received a fluoride dentifrice for home care and a fluoride varnish once every 3 months. Group 4 received a placebo dentifrice for home care and a fluoride rinse once a week. Fluoride rinsing did not give any additional effect compared with placebo-rinsing when a fluoride dentifrice was used for home care. Fluoride varnish gave a significant caries reduction compared with fluoride rinsing.
mesh_terms: D000293:Adolescent; D003731:Dental Caries / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005459:Fluorides / Q000008:administration & dosage*; D005460:Fluorides, Topical / Q000008:administration & dosage*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009067:Mouthwashes / Q000627:therapeutic use*; D010919:Placebos; D011897:Random Allocation; D013548:Sweden
chemical_list: D003802:Dentifrices; D005460:Fluorides, Topical; D009067:Mouthwashes; D010919:Placebos; D005459:Fluorides