Effect of sodium citrate on the blood disappearance of 67Ga.
The effect of sodium citrate on the blood disappearance of 67Ga was examined in rats. The half life value of the alpha phase and the initial AUC value (0-60 min) were dose-dependently decreased by sodium citrate. The binding of 67Ga to serum proteins was also dose-dependently inhibited by sodium citrate.
D000818:Animals; D001798:Blood Proteins / Q000378:metabolism; D002951:Citrates / Q000008:administration & dosage / Q000494:pharmacology*; D019343:Citric Acid; D005710:Gallium Radioisotopes / Q000097:blood* / Q000493:pharmacokinetics; D011485:Protein Binding / Q000187:drug effects; D051381:Rats
D001798:Blood Proteins; D002951:Citrates; D005710:Gallium Radioisotopes; D019343:Citric Acid