Immunoglobulins, complement components and lymphocyte subpopulations in Bell's palsy.
A significant decrease in the mean percentage of active and total T lymphocytes was found in 20 patients with Bell's palsy during the 1st week of the disease. In 8 patients the mean percentage of T helper cells was normal, whereas the mean percentage of T suppressor cells was significantly reduced. In 4 patients a normalization of the percentage of T lymphocytes and T suppressor cells was found 3 months after disease onset. The mean percentages of cells with membrane-bound immunoglobulins, EA- and EAC-rosetting cells and phagocytes were normal. Antibodies to peripheral nerve tissue were detected in low titers in 2 out of 20 sera. In the 20 patients the mean serum concentrations of IgG, IgA, IgM, IgE, C3 and C4 were normal.
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis; D000911:Antibodies, Monoclonal; D003165:Complement System Proteins / Q000378:metabolism*; D005158:Facial Paralysis / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000145:classification* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010525:Peripheral Nerves / Q000276:immunology; D013601:T-Lymphocytes / Q000473:pathology
D000906:Antibodies; D000911:Antibodies, Monoclonal; D007136:Immunoglobulins; D003165:Complement System Proteins