Grade and histochemical R-1881 binding in prostatic cancer.
Comparison of the grades classified by Gleason with R-1881 binding which was attributable to total androphilic proteins in tissues was performed in 42 untreated and 13 relapsed prostatic cancers. Increasing malignancy correlated with loss of staining on R-1881 binding when examined both in primary pattern and in individual tumor cell clusters. In relapsed cancer, however, there was no R-1881 binding irrespective of any grades.
D004963:Estrenes / Q000378:metabolism*; D006801:Humans; D008297:Male; D015741:Metribolone; D011471:Prostatic Neoplasms / Q000145:classification / Q000378:metabolism* / Q000473:pathology; D045165:Testosterone Congeners / Q000378:metabolism*
D004963:Estrenes; D045165:Testosterone Congeners; D015741:Metribolone