Pyrazolones and analgesic asthma syndrome.
Many peripherally acting analgesic and anti-inflammatory drugs, including pyrazolone derivatives, can precipitate idiosyncratic hypersensitivity reactions in intrinsic asthmatics. This contribution focuses on the symptomatology, diagnosis, and therapy ('desensitization') in childhood and adult analgesic asthma syndrome.
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects; D001249:Asthma / Q000139:chemically induced*; D002648:Child; D004177:Dipyrone / Q000009:adverse effects; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D011720:Pyrazoles / Q000009:adverse effects*; D047069:Pyrazolones; D013577:Syndrome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011720:Pyrazoles; D047069:Pyrazolones; D007073:Immunoglobulin E; C038362:pyrazolone; D004177:Dipyrone; D001241:Aspirin