[Bepridil and torsades de pointes. Apropos of 11 cases].
The authors report 11 cases of spikes occurring under bepridil treatment. It concerns an elderly population, predominantly female, receiving most of the time 300 mg of bepridil. The frequency of associated hypokalemic or arrhythmic medications is emphasized. The comparison of these results to those from other series in the literature, enables to propose precautions for the use of this molecule.
D000368:Aged; D000369:Aged, 80 and over; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D015764:Bepridil; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011759:Pyrrolidines / Q000009:adverse effects*; D013610:Tachycardia / Q000139:chemically induced*
D000889:Anti-Arrhythmia Agents; D011759:Pyrrolidines; D015764:Bepridil
Bépridil et torsades de pointes. A propos de 11 observations.