[Distribution of lymphocytes according to the cell cycle phases in T, B, D and O populations in human blood and the immune system organs of animals vaccinated against cholera].
The work presents the results of the study (carried out by the method of continuous flow cytofluorometry) of changes in the distribution of lymphocytes and their populations (obtained by means of distributing cell electrophoresis) according to the phases of the cell cycle (G0 + G1; S; G2 + M) in the blood and spleen of guinea pigs, as well as in the blood of humans, before and after immunization with cholera vaccine. The results of the determination of DNA-synthesizing lymphocytes in the blood of immunized humans and animals have been shown to serve as an objective characteristic for the complex evaluation of the biological activity of cholera vaccines.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology / Q000276:immunology; D002453:Cell Cycle; D022121:Cholera Vaccines / Q000276:immunology*; D004247:DNA / Q000096:biosynthesis; D005470:Fluorometry; D006168:Guinea Pigs; D006801:Humans; D007107:Immune System / Q000166:cytology* / Q000276:immunology; D007114:Immunization; D008214:Lymphocytes / Q000166:cytology* / Q000276:immunology; D008215:Lymphocytes, Null / Q000166:cytology / Q000276:immunology; D008875:Middle Aged; D013154:Spleen / Q000166:cytology / Q000276:immunology; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology
D022121:Cholera Vaccines; D004247:DNA
Raspredelenie limfotsitov po fazam kletochnogo tsikla v populiatsiiakh T, B, D, O v krovi liudeĭ i organakh immunoĭ sistemy zhivotnykh, vaktsinirovannykh protiv kholery.