The effect of pure LICAM(C) on the retention of plutonium-238 in mice and rats.
Studies with pure LICAM(C) and with its methyl esters showed that all the substances caused increased renal retention of plutonium-238 in the kidneys of mice and rats but were equally effective in reducing plutonium retention in bone and liver.
D000818:Animals; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism; D002614:Chelating Agents / Q000302:isolation & purification / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D005260:Female; D007668:Kidney / Q000187:drug effects / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D011005:Plutonium / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013095:Spermidine / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D014018:Tissue Distribution
D002614:Chelating Agents; D011005:Plutonium; C034834:LICAM-C; D013095:Spermidine