title: [Significance of laboratory diagnostic study parameters of the hepatobiliary system in the evaluation of cardiovascular diseases--results of cross sectional and longitudinal studies in patients with suspicious cardiovascular findings in an epidemiologic follow-up study].
abstract: With the help of an approx. 280 000 inhabitants check of x-ray-morphological suspects of a heart disease the laboratory parameters thymol turbidity test, zinc-sulphate turbidity test, total protein, serum protein electrophoresis and the enzymes "ASAT" and "ALAT" in longitudinal section and cross-section were examined in an intervention study during 5 years. All these parameters show standard values on the average, but compared to a healthy reference they showed significant differences, which relations to heart and vessel diseases could be deduced from. This referred especially to age-inverse behaviour of the transaminases only concerning male test persons. The examination of the longitudinal section confirmed exactly the results of the cross-section analysis. On the one hand it underlines the results got from the cross-section and in the second place it contributes to the efficient diagnostics by learning undone a repetition of these laboratory examinations during the period of 5 years with such a defined population. The relations of the particularities mentioned obviously refer to subclinical fields. Effects of therapy do not reflect in the laboratory findings.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism*; D003327:Coronary Disease / Q000175:diagnosis*; D003430:Cross-Sectional Studies; D005260:Female; D005859:Germany, East; D006801:Humans; D008111:Liver Function Tests; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D013431:Sulfates; D013943:Thymol; D015032:Zinc; D019287:Zinc Sulfate
chemical_list: D001798:Blood Proteins; D013431:Sulfates; D013943:Thymol; D019287:Zinc Sulfate; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D015032:Zinc
vernacular_title: Die Bedeutung labordiagnostischer Untersuchungsparameter des hepatobiliären Systems bei der Beurteilung von Herz-Kreislauf-Erkrankungen--Ergebnisse von Quer- und Längsschnitt-untersuchungen bei kardiovaskulär befundverdächtigen Probanden einer epidemiologischen Follow-up-Studie.