title: Appearance and development of neuron-specific enolase immunoreactivity in organotypic cultures of mouse embryo otocysts.
abstract: The appearance of neuron-specific enolase (NSE) immunoreactivity was studied in sensory and vestibular ganglion cells during the development of mouse embryo otocysts grown in vitro from the 13th gestation day. NSE appeared sequentially in the ganglion and sensory cell populations of the inner ear with a pattern that paralleled their successive maturation. Comparison with NSE immunoreactivity profile during in vivo development shows that NSE appears earlier during organotypic in vitro maturation.
mesh_terms: D000818:Animals; D001306:Auditory Pathways / Q000196:embryology* / Q000276:immunology; D002470:Cell Survival; D007758:Ear, Inner / Q000166:cytology / Q000196:embryology; D004622:Embryo, Mammalian / Q000276:immunology; D006651:Histocytochemistry; D007120:Immunochemistry; D051379:Mice; D009924:Organ Culture Techniques; D010751:Phosphopyruvate Hydratase / Q000276:immunology*; D014722:Vestibule, Labyrinth / Q000196:embryology / Q000276:immunology
chemical_list: D010751:Phosphopyruvate Hydratase