title: Gastrointestinal haemorrhage in burn patients.
abstract: Gastrointestinal haemorrhage after burn injury remains a potentially lethal problem. A retrospective review of 3852 burn patients over 15 years revealed an incidence of gastrointestinal haemorrhage of 2.2 per cent and a mortality of 0.16 per cent. This low incidence of haemorrhage and mortality can be directly related to an aggressive prophylactic treatment with antacid and titration of the gastric pH to 5.5 or above. With this aggressive management programme, few operative procedures were required. A review of autopsy data showed that the site of haemorrhage was distributed throughout the gastrointestinal tract with the predominant site being the stomach.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002056:Burns / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D004381:Duodenal Ulcer / Q000209:etiology; D005260:Female; D005745:Gastric Acidity Determination; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000209:etiology; D011379:Prognosis; D013276:Stomach Ulcer / Q000209:etiology