Cytogenetic study of a cell line of human penile cancer.
A cell line of penile cancer from a 60-year-old Ugandan black patient has been studied by the authors. Transmission and scanning electron microscopy showed a large number of blebs and microvilli at cell surface; desmosomes were evident at TEM. Cytogenetic investigation (R-, C-, Nor-banding) showed the frequent presence of some markers: del(1p),del(1q),iso(3q),der(4),del(8p),11q+, t rob(13;14), 14p+, t rob(21;21). The epidemiology, geographical distribution, and aetiological role of human papilloma virus type 16 and herpes simplex type 2 are discussed.
D002294:Carcinoma, Squamous Cell / Q000235:genetics* / Q000473:pathology / Q000648:ultrastructure; D002460:Cell Line; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000235:genetics* / Q000473:pathology / Q000648:ultrastructure
D005819:Genetic Markers