Congenital adrenal hyperplasia: long-term results following vaginal reconstruction.
Forty-two women with virilizing congenital adrenal hyperplasia who had attempted coitus were studied retrospectively a mean of 23.6 years after vaginal repair. Satisfactory intercourse, as defined by the patient, was observed in 62% of the subjects. The functional success rate was higher if repeat operations were performed after the age of 16 years (61% versus 12%, P less than 0.05) or if the patient suffered from the non-salt-losing variety of the disorder (87% versus 46%, P less than 0.05). The outcome of the initial attempt to exteriorize the vagina did not differ significantly by age at surgery. In cases of moderate virilization, vaginal repair may be delayed until the patient's menarche, maturity, and desires for sexual activity are well established. Clitoroplasty should be performed as soon as possible.
D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000209:etiology / Q000628:therapy*; D000367:Age Factors; D002675:Child, Preschool; D003075:Coitus; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D012086:Reoperation; D012189:Retrospective Studies; D013518:Surgery, Plastic; D013997:Time Factors; D014621:Vagina / Q000601:surgery*