Preproenkephalin mRNA in T-cells, macrophages, and mast cells.
The presence of preproenkephalin mRNA in tumor cell lines derived from myeloid and mast cells was analyzed by RNA dot blot hybridization. A B-cell lymphoma was negative for preproenkephalin mRNA, but several T-cell lymphomas were positive. A mastocytoma and two macrophage cell lines were found to have high levels of preproenkephalin mRNA. Purified natural macrophages and mast cells also possessed easily detectable levels of this mRNA.
D000818:Animals; D002460:Cell Line; D004745:Enkephalins / Q000032:analysis* / Q000235:genetics; D008264:Macrophages / Q000032:analysis*; D008407:Mast Cells / Q000032:analysis*; D051379:Mice; D009693:Nucleic Acid Hybridization; D011498:Protein Precursors / Q000032:analysis* / Q000235:genetics; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D013601:T-Lymphocytes / Q000032:analysis*
D004745:Enkephalins; D011498:Protein Precursors; D012333:RNA, Messenger; C033660:preproenkephalin