An international study on the serological differential diagnosis of human cystic and alveolar echinococcosis.
An enzyme-linked immunosorbent assay (ELISA) for the serological differentiation of cystic (Echinococcus granulosus) and alveolar (E. multilocularis) echinococcosis in man has been evaluated. A discrimination rate of 95.1% was found for 82 sera from patients of geographically disparate endemic areas. This rate was essentially the same as that found for 57 Swiss patients, indicating that inter- and intraspecific strain differences do not influence the test results. The assay method is suitable for immunodiagnostic purposes as well as for seroepidemiological studies.
D000293:Adolescent; D000328:Adult; D003937:Diagnosis, Differential; D004443:Echinococcosis / Q000175:diagnosis* / Q000469:parasitology; D004444:Echinococcosis, Hepatic / Q000175:diagnosis / Q000469:parasitology; D004445:Echinococcosis, Pulmonary / Q000175:diagnosis / Q000469:parasitology; D004446:Echinococcus / Q000145:classification; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008875:Middle Aged