title: Effect of pH, concentration, and treatment time of aluminum solutions on acid dissolution of enamel.
abstract: Dissolution tests were conducted with human enamel following treatment with aqueous aluminum (Al) solutions under conditions of varying pH, concentration, and treatment time. Al reduced enamel dissolution in a pH 4 acetate buffer most effectively when used in the pH range of 3 to 4, at concentrations above 0.005 mol/L, and for treatment times of more than four minutes. However, significant activity was observed with concentrations as low as 0.0005 mol/L Al and treatment times as short as 15 seconds. The effects of Al solution pH and concentration on enamel dissolution were related to the hydrolysis of Al above pH 4 and to the accelerated dissolution of apatite below pH 3.
mesh_terms: D000143:Acids; D000535:Aluminum / Q000008:administration & dosage / Q000494:pharmacology*; D003743:Dental Enamel / Q000187:drug effects; D003747:Dental Enamel Solubility / Q000187:drug effects*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D012995:Solubility; D013997:Time Factors
chemical_list: D000143:Acids; D000535:Aluminum