title: [Diagnostic procedure in suspected Sjögren syndrome].
abstract: Basing on anamnestic and clinical findings in Sjögren's syndrome, methods of examination of the salivary glands are outlined. The flow rate and composition of the saliva, especially sodium and IgM contents, are important points of diagnosis. Serological methods are described, such as examination of antibodies to nuclear antigens and their subunits SS-A and SS-B. Labial salivary gland biopsy rounds off the diagnostic procedure. Patients with Sjögren's syndrome must be controlled regularly because of the above-average risk of developing non-Hodgkin lymphoma.
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000378:metabolism; D012470:Salivary Glands, Minor / Q000473:pathology; D012796:Sialography; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000473:pathology; D013666:Tears / Q000378:metabolism
chemical_list: D000974:Antibodies, Antinuclear
vernacular_title: Diagnostisches Vorgehen bei Verdacht auf Sjögren-Syndrom.