Effects of denervation on cell-to-cell communication between acinar cells of rat submandibular salivary gland.
Communication measured by electrical cell coupling and dye transfer decreased transiently 1 day after parasympathectomy and then recovered 2 days later. Parasympathectomy decreased communication again 2 weeks later, coinciding with a decrease in the wet weight of the gland, but sympathectomy did not affect it. Thus parasympathetic nerve activity may be required for the regulation and maintenance of cell-to-cell communication in the rat submandibular gland.
D000818:Animals; D002450:Cell Communication; D003714:Denervation; D008297:Male; D010275:Parasympathetic Nervous System / Q000502:physiology / Q000601:surgery; D051381:Rats; D011919:Rats, Inbred Strains; D013363:Submandibular Gland / Q000166:cytology* / Q000294:innervation / Q000502:physiology; D013562:Sympathectomy