The relationship between descending serotonin projections and ascending projections in the nucleus raphe magnus: a double labeling study.
The nucleus raphe magnus and rostral parts of the nucleus raphe obscurus were found to have extensive efferent projections: a major ascending non-serotonergic (5-HT) projection through the median forebrain bundle, and a descending system consisting of both 5-HT and non-5-HT neurons. Differences in the localizations of their cells of origin suggest that they form two distinct efferent systems from the caudal medullary raphe nuclei.
D000818:Animals; D008474:Medial Forebrain Bundle / Q000033:anatomy & histology; D009434:Neural Pathways / Q000033:anatomy & histology; D011903:Raphe Nuclei / Q000033:anatomy & histology*; D051381:Rats; D011919:Rats, Inbred Strains; D012154:Reticular Formation / Q000033:anatomy & histology; D012701:Serotonin / Q000378:metabolism*; D013116:Spinal Cord / Q000033:anatomy & histology
D012701:Serotonin