Radionuclides in lung diagnostics: a new approach. Summary of the first results.
With a 99mTc-labelled aerosol an inhalation (ventilation) image of the lungs was obtained. A lung perfusion image was obtained with 99mTc-labelled macro-aggregates. The data from the gamma camera were stored in a computer and the inhalation-perfusion (I/P) ratio was calculated for the total lung as well as for one half, another selected region, and a local (pixel) area. In the anaesthetised dog in sternal recumbency, the I/P ratio decreased from the cranial to the caudal lung regions. Hence in the dog gravity is not the only determinant of the I/P ratio distribution, as it is assumed to be in man. Position and anaesthesia appeared to influence the distribution of I/P ratios within the lung.
D000818:Animals; D004285:Dogs / Q000502:physiology*; D005260:Female; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D011659:Pulmonary Gas Exchange; D011877:Radionuclide Imaging; D014692:Ventilation-Perfusion Ratio