[Sensitizing properties of soluble Haemophilus influenzae antigens].
The sensitizing properties of different doses of the antigenic preparation obtained from H. influenzae by ultrasonic treatment have been studied. Small doses of the antigen have been found to induce immunoallergic transformations of type IV in sensitized guinea pigs. A considerable increase in the sensitizing dose of the antigen has been found to lead to the appearance of allergic reactions of type I. The regularities of the development of allergy to H. influenzae are discussed.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000032:analysis; D000942:Antigens, Bacterial / Q000276:immunology*; D002464:Cell Migration Inhibition; D004306:Dose-Response Relationship, Immunologic; D006168:Guinea Pigs; D006193:Haemophilus influenzae / Q000276:immunology*; D006968:Hypersensitivity, Delayed / Q000276:immunology; D006969:Hypersensitivity, Immediate / Q000276:immunology; D007114:Immunization; D007962:Leukocytes / Q000276:immunology; D010323:Passive Cutaneous Anaphylaxis; D012882:Skin Tests; D012995:Solubility; D013997:Time Factors
D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial
Izuchenie sensibiliziruiushchikh svoĭstv rastvorimykh antigenov Haemophilus influenzae.