Major locus for red hair color linked to MNS blood groups on chromosome 4.
Red hair color (RHC) was studied in a Danish material of normal families that was tested earlier for 65 marker systems. We found 4.85% of the parents to be red-haired or to have been so early in life. Scoring RHC for linkage as an autosomal dominant against blond and as hypostatic to dark hair gave a lod score of z = 5.50 at theta = 0.05 in males and theta = 0.24 in females for the MNS blood group system; this assigns a major locus for red hair to chromosome 4.
D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4; D005260:Female; D005799:Genes, Dominant; D008040:Genetic Linkage; D005819:Genetic Markers; D006200:Hair Color / Q000235:genetics*; D006801:Humans; D008951:MNSs Blood-Group System / Q000235:genetics*; D008297:Male
D005819:Genetic Markers; D008951:MNSs Blood-Group System