T-cell origin of Lennert's lymphoma.
The arrangement of the T-cell receptor and immunoglobulin genes has been analysed in five cases of Lennert's lymphoma. All cases showed rearrangement of the gene coding for the beta chain of the T-cell receptor and a germline configuration of the immunoglobulin genes. This provides strong evidence that Lennert's lymphoma is a T-cell lymphoma.
D000911:Antibodies, Monoclonal; D005838:Genotype; D006801:Humans; D007136:Immunoglobulins / Q000235:genetics; D008223:Lymphoma / Q000235:genetics* / Q000276:immunology; D011948:Receptors, Antigen, T-Cell / Q000235:genetics; D013601:T-Lymphocytes / Q000276:immunology*
D000911:Antibodies, Monoclonal; D007136:Immunoglobulins; D011948:Receptors, Antigen, T-Cell