Some factors influencing the survival of patients with less advanced stages of differentiated thyroid cancer.
Two groups of patients with less advanced stages of differentiated thyroid cancer were followed from 2 to more than 25 years: 1. 326 patients with preventive thyroid ablation (PTA) in cases of a tumor without lymphatic and remote metastases; 2. 471 patients with lymph node syndrome. It was found that the survival of patients with lymph node syndrome was less including the group below 40 years of age. Within the first group (with PTA) the survival was less in cases with the invasion of tumor through the thyroid capsula (stage T3 according to WHO classification). In both groups neither any significant effect of sex nor histological characteristics of the tumor (i.e. papillary v.s. follicular) was found. However, the effect of age was found to be remarkable in both groups, the prognosis being worse in patients after 40 years of age. Finally, the prognosis of less advanced stages of differentiated cancer was much better than than in patients with remote metastases.
D000230:Adenocarcinoma / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D000328:Adult; D002291:Carcinoma, Papillary / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009362:Neoplasm Metastasis; D013964:Thyroid Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D013997:Time Factors