title: [Prostaglandins and the immunological indices of patients with chronic heart failure].
abstract: Some indices of T and B cellular immunity and content of PgE2 and PgF2 alpha in the peripheral blood plasma were studied in 70 patients with coronary heart disease and in 22 patients with rheumatic disease complicated by chronic cardiac failure. It was revealed that increase in PgE2 and PgF2 alpha levels was accompanied by changes in T cells subpopulations. It is suggested that Pg-s can mediate changes of immunoregulatory lymphocyte functions in chronic cardiac insufficiency.
mesh_terms: D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D002908:Chronic Disease; D003324:Coronary Artery Disease / Q000097:blood / Q000276:immunology; D015237:Dinoprost; D015232:Dinoprostone; D005260:Female; D006333:Heart Failure / Q000097:blood* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D011458:Prostaglandins E / Q000097:blood*; D011460:Prostaglandins F / Q000097:blood*; D012214:Rheumatic Heart Disease / Q000097:blood / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D011458:Prostaglandins E; D011460:Prostaglandins F; D015237:Dinoprost; D015232:Dinoprostone
vernacular_title: Prostaglandiny i nekotorye immunologicheskie pokazateli u bol'nykh s khronicheskoĭ serdechnoĭ nedostatochnost'iu.