title: CSF evaluation in neurologic disease.
abstract: Contraindications to performing a lumbar puncture include local infection, intracranial hypertension and complete spinal block. Routine parameters include pressure, appearance, glucose, protein and cytology. Specific studies such as antigen-antibody tests may identify infectious agents. The color of the CSF may indicate infection, previous hemorrhage or, rarely, metastatic melanoma. The IgG-albumin index is useful when there is inflammation, as in multiple sclerosis.
mesh_terms: D002493:Central Nervous System Diseases / Q000134:cerebrospinal fluid*; D002555:Cerebrospinal Fluid / Q000166:cytology; D002556:Cerebrospinal Fluid Proteins; D003378:Counterimmunoelectrophoresis; D003453:Cryptococcosis / Q000134:cerebrospinal fluid; D004731:Endotoxins / Q000134:cerebrospinal fluid; D005947:Glucose / Q000134:cerebrospinal fluid; D006801:Humans; D007136:Immunoglobulins / Q000134:cerebrospinal fluid; D007427:Intracranial Pressure; D008033:Limulus Test; D008581:Meningitis / Q000134:cerebrospinal fluid; D009494:Neurosyphilis / Q000134:cerebrospinal fluid; D013129:Spinal Puncture / Q000009:adverse effects
chemical_list: D002556:Cerebrospinal Fluid Proteins; D004731:Endotoxins; D007136:Immunoglobulins; D005947:Glucose