title: Diversity of some gene frequencies in European and Asian populations. III. Spatial correlogram analysis.
abstract: The gene frequencies at eight loci in some European and Asian human populations have been subjected to spatial autocorrelation analysis, using Geary's c coefficient. Contrary to what is expected for markers affected only by gene flow and genetic drift, the spatial correlograms show distinct modes of gene frequency variation: there are significant clinal patterns (at the GLO and ESD loci), significant non-clinal patterns (AK, ADA, 6-PGD and GPT) and marginally significant patterns (PGP and SOD). Any hypothesis on the evolution of these polymorphisms should account for the observed heterogeneity of their geographical distributions.
mesh_terms: D001208:Asia; D005060:Europe; D005787:Gene Frequency; D005819:Genetic Markers; D014644:Genetic Variation; D005828:Genetics, Population; D006867:Hydrolases / Q000235:genetics; D008190:Lyases / Q000235:genetics; D010088:Oxidoreductases / Q000235:genetics; D014166:Transferases / Q000235:genetics
chemical_list: D005819:Genetic Markers; D010088:Oxidoreductases; D014166:Transferases; D006867:Hydrolases; D008190:Lyases