Effects of acid-base status and fluoride on the composition of the mineral in developing enamel and dentine in the dog.
Developing molar teeth of the dog were sectioned, embedded in copper containing polymethyl methacrylate, polished and their Ca/P and Ca/Na molar ratios investigated with the electron microprobe. The teeth were obtained at 30 days from 9 pups fed regimes of different acid-base status with or without fluoride supplementation from birth to sacrifice at 30 days. No clear trends in their Ca/P or Ca/Na ratios with variation in the diet were observed. However, evaluation of the Ca/P ratio of the enamel as a function of depth revealed that this ratio was 0.80 +/- 0.15 at the mineralization front. This suggests that in enamel brushite rather than octacalcium phosphate is the precursor phase of the mineral.
D000138:Acidosis / Q000378:metabolism*; D000471:Alkalosis / Q000378:metabolism*; D000818:Animals; D002118:Calcium / Q000032:analysis; D002130:Calcium Phosphates / Q000032:analysis; D003743:Dental Enamel / Q000032:analysis*; D003804:Dentin / Q000032:analysis*; D004285:Dogs; D005459:Fluorides / Q000008:administration & dosage / Q000494:pharmacology*; D008903:Minerals / Q000032:analysis*; D009805:Odontogenesis; D010758:Phosphorus / Q000032:analysis; D012964:Sodium / Q000032:analysis; D014074:Tooth Calcification
D002130:Calcium Phosphates; D008903:Minerals; D010758:Phosphorus; D012964:Sodium; C494366:calcium phosphate, dibasic, dihydrate; D005459:Fluorides; D002118:Calcium