Single-dose trimethoprim-sulfamethoxazole prophylaxis for cesarean section.
Single-dose trimethoprim-sulfamethoxazole prophylaxis after clamping of the umbilical cord decreased the rate of endomyometritis in high-risk patients by 50% when compared with placebo. This drug combination may affect the normal flora of the cervix the least so that superinfections should be rare.
D000293:Adolescent; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002585:Cesarean Section; D004338:Drug Combinations / Q000008:administration & dosage / Q000627:therapeutic use; D004716:Endometritis / Q000517:prevention & control*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011292:Premedication; D011897:Random Allocation; D012306:Risk; D013420:Sulfamethoxazole / Q000008:administration & dosage / Q000627:therapeutic use*; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014295:Trimethoprim / Q000008:administration & dosage / Q000627:therapeutic use*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D000890:Anti-Infective Agents; D004338:Drug Combinations; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013420:Sulfamethoxazole