Prevalence of Rett syndrome in Switzerland.
In an extensive survey, 35 cases of Rett syndrome born in Switzerland were found. Only 5 probands were older than 20 years; the oldest subject was 37. The prevalence for 1967-1982 was 0.41/10,000 (= 1:24,600) girls. This is considered a minimum prevalence since complete ascertainment was not possible by this investigation. Prevalence figures from southern Sweden and west of Scotland are higher (approximately 1:15,000). Rett syndrome is apparently responsible for a considerable proportion of girls with neurodegenerative disorders.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000453:epidemiology*; D009468:Neuromuscular Diseases / Q000453:epidemiology*; D013239:Stereotyped Behavior; D013557:Switzerland; D013577:Syndrome