Craniopharyngioma in Finland. A study of 123 cases.
We report on 123 patients with craniopharyngioma diagnosed in Finland from 1951 to 1982. 45 patients were under 16 years of age at the time of diagnosis and 78 over 16 years. The age-distribution had peaks at 11-20 years and at 41-50 years. 115 patients were operated on; operation was radical in 67 cases (58%). Surgical mortality was 13%. The number of radical operations increased and surgical mortality decreased after 1970. Recurrence developed in 26 patients (21%), 11 after a radical and 15 after a non-radical operation. Recurrence-free survival, 10-year survival and life expectancy were best after radical operation. We consider that radical operation is the best treatment. For patients with a non-radical operation or with recurrence modern radiotherapy gives long-lasting relief.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003397:Craniopharyngioma / Q000401:mortality / Q000601:surgery*; D003430:Cross-Sectional Studies; D005260:Female; D005387:Finland; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010910:Pituitary Irradiation; D010911:Pituitary Neoplasms / Q000401:mortality / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis