[Cellular immunity factors of tick-borne typhus patients in northern Asia].
In patients with North Asian tick-borne typhus fever the deficiency of the T-system of immunity, most pronounced in the acute period of the disease, is observed, which is manifested by low values of lymphocyte blast-transformation and rosette-formation. A decrease in the number of active E-rosette-forming cells depends on the severity of the disease. The shifts in the T-system of immunity, appearing in patients with North Asian tick-borne typhus fever, are compensated for comparatively quickly, the normalization of the functional activity of T-lymphocytes occurring sooner than the restoration of their number. The specific dynamics of the characteristics of cell-mediated immunity in patients with North Asian tick-borne typhus fever is accompanied by a comparatively mild course of the disease and its favorable outcome.
D000328:Adult; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D012282:Rickettsia Infections / Q000276:immunology*; D012397:Rosette Formation; D012800:Siberia; D013601:T-Lymphocytes / Q000276:immunology*; D013997:Time Factors
Kletochnye faktory immuniteta u bol'nykh kleshchevym sypnym tifom Severnoĭ Azii.