Chronic Ureaplasma urealyticum amnionitis associated with abruptio placentae.
Ureaplasma urealyticum is a common inhabitant of the lower genital tract of women. It is unclear whether or not the microorganism plays a role in provoking spontaneous abortion. Reported is a U urealyticum infection of placenta and amniotic fluid in an immunologically competent host resulting in abruptio placentae and spontaneous abortion during the second trimester of pregnancy. U urealyticum was isolated from peripheral maternal blood twice. Immunologic alterations, namely a transiently reversed OKT4/OKT8 rate and a decrease in immunoglobulin G levels, were detected in the patient. U urealyticum must be considered as a pathogen able to interfere with normal fetal development.
D000022:Abortion, Spontaneous / Q000209:etiology; D000037:Abruptio Placentae / Q000209:etiology*; D000328:Adult; D001424:Bacterial Infections / Q000276:immunology / Q000382:microbiology*; D002821:Chorioamnionitis / Q000382:microbiology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D008423:Maternal Age; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D011262:Pregnancy Trimester, Second; D018566:Pregnancy, High-Risk; D013601:T-Lymphocytes / Q000145:classification; D014509:Ureaplasma / Q000276:immunology / Q000302:isolation & purification*
D007074:Immunoglobulin G