title: [Efficacy of various methods of therapy of chronic brucellosis].
abstract: A study was made of the comparative efficacy of levamisole (a controlled method) and vaccinotherapy in combined treatment of 97 patients with chronic brucellosis. The advantage of levamisole curative effect in the period of exacerbation and in a follow-up period was obvious. No advantage of vaccinotherapy in chronic brucellosis was noted. An immunomodulating effect of levamisole was manifested in an increase in the amount of circulating lymphocyte subpopulations. No similar changes of immunological indices in vaccinotherapy were noted.
mesh_terms: D000293:Adolescent; D000328:Adult; D002004:Brucella Vaccine / Q000627:therapeutic use*; D002006:Brucellosis / Q000276:immunology / Q000628:therapy*; D002908:Chronic Disease; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D002004:Brucella Vaccine; D007978:Levamisole
vernacular_title: Effektivnost' razlichnykh metodov lecheniia khronicheskogo brustelleza.