Increased activation of antigen-primed or memory B cells by bacterial lipopolysaccharide.
Treatment with bacterial lipopolysaccharide elicits the appearance of greater numbers of background antigen-specific plaque-forming cells (PFC) in the spleens of mice previously exposed or primed to subimmunogenic amounts of various non-cross-reacting antigens so as to generate detectable immunological memory. These findings suggest that treatment with lipopolysaccharide results in the activation of increased numbers of antigen-primed or memory B cells in mice previously exposed to antigen.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D003429:Cross Reactions; D007156:Immunologic Memory; D008070:Lipopolysaccharides / Q000276:immunology*; D008213:Lymphocyte Activation; D051379:Mice; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D013997:Time Factors
D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial