The occurrence of HLA-DR2 in clinically established narcolepsy.
Of 25 patients with a longstanding diagnosis of narcolepsy 23 were HLA-DR2 positive. The 2 DR2 negative patients were misdiagnosed when retrospectively interviewed. HLA-DR2 determination is a valuable tool for ascertaining the narcolepsy diagnosis in uncertain cases.
D000328:Adult; D000368:Aged; D006681:HLA-D Antigens / Q000032:analysis*; D006684:HLA-DR Antigens / Q000032:analysis*; D015802:HLA-DR2 Antigen; D006801:Humans; D008875:Middle Aged; D009290:Narcolepsy / Q000276:immunology*
D006681:HLA-D Antigens; D006684:HLA-DR Antigens; D015802:HLA-DR2 Antigen