[Anomalous sedimentation schlieren diagrams of the blood in patients with rheumatic diseases as an indicator of the presence of reversibly dissociating immune complexes].
Circulating immune complexes (CIC) are of considerable importance in the pathogenesis of rheumatoid diseases. The study of CIC has so far been restricted to their stable forms. This paper presents the data of ultracentrifugation showing that sera from rheumatoid patients often contain special population of reversibly dissociating CIC. It is noted that antibodies forming such kinds of CIC might either be present in significant excess, as compared to antigens, or possess low affinity.
D000936:Antigen-Antibody Complex / Q000032:analysis*; D006801:Humans; D008722:Methods; D012216:Rheumatic Diseases / Q000097:blood* / Q000276:immunology
D000936:Antigen-Antibody Complex
Anomal'nye sedimentatsionnye shliren-diagrammy syvorotki krovi bol'nykh revmaticheskimi bolezniami kak indikator prisutstviia obratimo dissotsiiruiushchikh immunnykh kompleksov.