Effect of serotonin on T lymphocyte proliferation in vitro in healthy individuals.
The direct effect of different concentrations of serotonin on T lymphocyte proliferation in vitro was seen in 20 normal individuals. It has been observed that the neurotransmitter had a suppressive effect on mitogen-induced lymphocyte proliferation. This study shows that the effect of serotonin on the immune system is direct.
D002478:Cells, Cultured; D006801:Humans; D007165:Immunosuppression Therapy; D008213:Lymphocyte Activation / Q000187:drug effects*; D010835:Phytohemagglutinins / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000276:immunology*
D010835:Phytohemagglutinins; D012701:Serotonin