[Myasthenia induced by D-penicillamine. Apropos of 2 case reports].
Two cases of penicillamine-induced myasthenia gravis in rheumatoid polyarthritis are reported. A complete recovery was obtained in both cases. The authors discuss the clinical presentation and the pathogenetic mechanisms of that drug-induced myasthenia gravis. The presence in both cases of both the HLA antigens DR1 and BW35 is emphasized.
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D005260:Female; D006680:HLA Antigens; D015797:HLA-B35 Antigen; D006684:HLA-DR Antigens; D015798:HLA-DR1 Antigen; D006801:Humans; D009157:Myasthenia Gravis / Q000139:chemically induced* / Q000276:immunology; D010396:Penicillamine / Q000009:adverse effects* / Q000627:therapeutic use
D006680:HLA Antigens; D015797:HLA-B35 Antigen; D006684:HLA-DR Antigens; D015798:HLA-DR1 Antigen; D010396:Penicillamine
Myasthénie induite par la D-pénicillamine. A propos de deux observations.