title: [Comparative coagulation studies in induced therapeutic abortions with prostaglandin].
abstract: Therapeutic abortion in the first trimester of pregnancy have been done in ten primigravidae using PGF2 alpha, 15-methyl-PGF2 alpha, or Sulprostone. Bleeding and recalcification time, platelet count, fibrin, platelet adhesiveness, partial thromboplastin time and thromboplastin time were examined before, during and after treatment. We found a decrease of platelet count and a prolongation of bleeding and recalcification time. There was no intensive-influence on coagulation system by the prostaglandin used. Therefore prostaglandins may be used for therapeutic abortion.
mesh_terms: D000019:Abortifacient Agents / Q000009:adverse effects; D000020:Abortifacient Agents, Nonsteroidal / Q000009:adverse effects; D000028:Abortion, Induced; D000293:Adolescent; D000328:Adult; D001779:Blood Coagulation Factors / Q000378:metabolism; D001780:Blood Coagulation Tests; D002260:Carboprost / Q000009:adverse effects; D015237:Dinoprost; D015232:Dinoprostone / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D010976:Platelet Count / Q000187:drug effects; D011247:Pregnancy; D011459:Prostaglandins E, Synthetic / Q000009:adverse effects; D011460:Prostaglandins F / Q000009:adverse effects; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects
chemical_list: D000019:Abortifacient Agents; D000020:Abortifacient Agents, Nonsteroidal; D001779:Blood Coagulation Factors; D011459:Prostaglandins E, Synthetic; D011460:Prostaglandins F; D011461:Prostaglandins F, Synthetic; C016767:sulprostone; D002260:Carboprost; D015237:Dinoprost; D015232:Dinoprostone
vernacular_title: Vergleichende Gerinnungsuntersuchungen bei induzierten therapeutischen Aborten mittels Prostaglandin.