Arugomycin, a new anthracycline antibiotic. II. Structural elucidation.
The structure of arugomycin was determined by chemical degradation, and NMR and mass spectral analyses to be a new anthracycline antibiotic with arugorol (4'-epi-nogalarol) as the chromophore and two sugar chains comprising diginosyl-decilonitrosyl-2-deoxyfucose, and (4-O-fumaryl-diginosyl)-diginosyl-2-deoxyfucosyl -diginose.
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009279:Naphthacenes; D013055:Spectrophotometry, Infrared; D013329:Structure-Activity Relationship
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes; C040037:arugomycin