Genetic markers in patients with intracranial aneurysms.
HLA antigens, blood group systems (ABO, Rh, MNSs, P, Kell, Lewis and Duffy) and serum group systems (Hp, Tf, Gc, Pi, Bf, C3 and C4) were studied in a series of patients with intracranial aneurysms. A significantly increased frequency of HLA antigen A28, a significantly decreased frequency of HLA antigen B40, and a significantly decreased frequency of complement factor C4 B2 was found among the patients when compared with controls from the same geographic area.
D003181:Complement C4 / Q000235:genetics; D015935:Complement C4b; D005819:Genetic Markers; D006680:HLA Antigens / Q000235:genetics; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D059947:HLA-B40 Antigen; D006801:Humans; D002532:Intracranial Aneurysm / Q000235:genetics* / Q000276:immunology
D003181:Complement C4; D005819:Genetic Markers; D006680:HLA Antigens; D015234:HLA-A Antigens; C037164:HLA-A28 antigen; D015235:HLA-B Antigens; D059947:HLA-B40 Antigen; D015935:Complement C4b