title: [Total femur replacement in osteogenic sarcoma of the femur].
abstract: A 14-year-old girl was admitted with a diagnosis of osteogenic sarcoma of the distal femur. Pre-operative chemotherapy was effective, and sclerosis of the lesion made clear the presence of a proximal femoral and pulmonary metastasis. Total femur and knee joint replacement with titanium alloy was made after a total resection of the femur. Her post-operative clinical course was excellent without local recurrence. Now, 14 months after the operation, she can walk without crutches. We wish to emphasize that the presence of a pulmonary metastasis is not absolutely a contraindication as long as the tumor appears surgically resectable and responsive to per-operative chemotherapy.
mesh_terms: D000293:Adolescent; D001672:Biocompatible Materials; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005269:Femur / Q000601:surgery*; D006801:Humans; D007720:Knee Prosthesis; D012516:Osteosarcoma / Q000188:drug therapy / Q000601:surgery*; D019736:Prostheses and Implants
chemical_list: D001672:Biocompatible Materials