PET before and after surgery for tumor-induced parkinsonism.
We studied a patient with left frontal meningioma and right-sided parkinsonism that resolved completely after operation. PET scans were performed before and after operation to measure regional cerebral blood flow, oxygen extraction ratio, oxygen utilization, and blood volume. A specific pattern of severe functional changes returned to normal postoperatively. The data suggest increased local tissue pressure due to edema, causing a functional disorder in the left basal ganglia that gave rise to reversible contralateral parkinsonism.
D001810:Blood Volume; D002560:Cerebrovascular Circulation; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D008579:Meningioma / Q000000981:diagnostic imaging* / Q000601:surgery; D008875:Middle Aged; D010101:Oxygen Consumption; D010300:Parkinson Disease / Q000000981:diagnostic imaging* / Q000601:surgery; D011184:Postoperative Period; D014055:Tomography, Emission-Computed