title: Magnetic resonance imaging (MRI), cranial computerized tomography (CCT), evoked potentials and cerebrospinal fluid (CSF) analysis in five patients with funicular myelosis.
abstract: Five Patients with vitamin B12 deficiency were examined by means of MRI, CCT, VEP, BAEP, EEG, and CSF. In 3 patients medianus-SEP and EMG/ENG were recorded as well. Partly, findings of MRI, CCT, VEP, BAEP, SEP, and CSF were similar to those in multiple sclerosis. This is not very surprising considering that the central nervous system lesions in vitamin B12 deficiency consist of disseminated demyelination. Because of this all these investigative techniques must be considered non-specific. Appraisal of findings is only possible in connection with the case history, clinical findings, and supplementary diagnostic measurements.
mesh_terms: D000888:Antibodies, Anti-Idiotypic / Q000032:analysis; D001812:Blood-Brain Barrier; D001855:Bone Marrow Diseases / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001921:Brain / Q000000981:diagnostic imaging*; D004576:Electromyography; D005071:Evoked Potentials; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D008279:Magnetic Resonance Imaging; D009186:Myelin Sheath / Q000648:ultrastructure; D009422:Nervous System Diseases / Q000150:complications / Q000175:diagnosis; D043025:Oligoclonal Bands; D009900:Optic Nerve / Q000473:pathology; D013118:Spinal Cord Diseases / Q000134:cerebrospinal fluid / Q000000981:diagnostic imaging* / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
chemical_list: D000888:Antibodies, Anti-Idiotypic; D007136:Immunoglobulins; D043025:Oligoclonal Bands