Inflammatory reaction as an occlusive mechanism in aortocoronary bypass grafts?
Morphological changes in aortocoronary vein grafts are described in two cases; one dying 5 hours post operatively and the other reoperated 8 months after aortocoronary bypass surgery for graft occlusion. Occlusive thrombi and fibrin deposition on the intimal surface and a focal inflammatory process in the wall of the vein grafts were found in the former. Thrombotic encrustation and organization similar to the manifestations of the thrombogenic theory of atherosclerosis were demonstrated in the latter.
D000328:Adult; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D006083:Graft Occlusion, Vascular / Q000209:etiology*; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D008297:Male