Metabolism of 3-nitrophenol by the frog Rana temporaria.
Frogs injected with 3-nitrophenol excreted 85-93% of the administered dose within 17 h; 70-90% dose was metabolized. Metabolites identified comprise 3-nitrophenyl glucuronide (57% dose), 3-nitrophenyl sulphate (24% dose), and 3-acetamidophenyl sulphate (2% dose). Traces of the following metabolites were found: 3-acetamidophenyl glucuronide, 3-acetamidophenol, 4-nitrocatechol, nitroquinol, 4-nitrocatechol sulphate and nitroquinol sulphate.
D000818:Animals; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D006868:Hydrolysis; D009596:Nitrophenols / Q000378:metabolism*; D011896:Rana temporaria
D009596:Nitrophenols; C049017:3-nitrophenol