title: Comparison of 2 g single dose of metronidazole, nimorazole and tinidazole in the treatment of vaginitis associated with Gardnerella vaginalis.
abstract: Vaginitis associated with the presence of Gardnerella vaginalis (confirmed by culture) was treated either with metronidazole or with one of the two nitroimidazole derivatives; nimorazole or tinidazole, as a single oral 2 g dose. Eighty-two patients were treated with metronidazole, 100 with nimorazole and 98 with tinidazole. The cure rates were 79%, 88% and 92% with metronidazole, nimorazole and tinidazole respectively. Therefore we recommend a single dose of 2 g of any of these three drugs in the treatment of such infection.
mesh_terms: D005260:Female; D006194:Gardnerella vaginalis / Q000187:drug effects; D006192:Haemophilus Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D009554:Nimorazole / Q000627:therapeutic use*; D009593:Nitroimidazoles / Q000627:therapeutic use*; D012008:Recurrence; D014011:Tinidazole / Q000627:therapeutic use*; D014627:Vaginitis / Q000188:drug therapy*
chemical_list: D009593:Nitroimidazoles; D014011:Tinidazole; D008795:Metronidazole; D009554:Nimorazole