title: Consequence of excess iodine supply in a Thoroughbred stud in southern Brazil.
abstract: Excessive iodine supply of at least 700 mg inorganic iodine in foals and of more than 350 mg iodine in pregnant and lactating mares cause a high incidence of goitres in the newborn and disorders in the long leg bones of foals. Elevated phosphorus and alkaline phosphatase content in the blood may indicate a severe disturbance in the bone metabolism. Of 39 pregnant mares 17 aborted and some of the mares also showed goitres. After withdrawal of the iodine supply normalization took place. Foals born more than 6 weeks later showed normal conditions. The goitres in the mares and the high blood levels of iodine decreased.
mesh_terms: D000818:Animals; D004032:Diet / Q000009:adverse effects; D005260:Female; D006042:Goiter / Q000139:chemically induced / Q000662:veterinary; D006734:Horse Diseases / Q000139:chemically induced*; D006736:Horses; D007455:Iodine / Q000009:adverse effects* / Q000032:analysis; D008892:Milk / Q000032:analysis; D010022:Osteopetrosis / Q000139:chemically induced / Q000662:veterinary; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced / Q000662:veterinary*
chemical_list: D007455:Iodine