Arterial blood flow in deep venous thrombosis of the lower limbs.
Calf blood flow was measured in 19 patients with deep venous thrombosis (DVT) of the lower limb using a mercury strain gauge. The affected limb had a significantly (P less than 0.05) higher blood flow (2.9 +/- 1.4 ml/min. 100 g of tissue) then the contralateral limb (2.3 +/- 1.2 ml/min. 100 g). Blood flow velocity in the common femoral artery measured with a pulsed Doppler ultrasound flowmeter in 13 patients was also significantly (P less than 0.05) higher in the limb with DVT (6.6 +/- 2.8 cm/s) compared to the contralateral limb (5.3 +/- 3.0 cm/s). Interstitial fluid hydrostatic pressure (Pif) was measured by the "wick-in-needle" technique in the deep posterior compartment of the leg. There was a significant (P less than 0.001) increase in the limb with DVT (6.3 +/- 5.5 mmHg) compared to the contralateral limb (1.2 +/- 3.4 mmHg).
D000368:Aged; D000369:Aged, 80 and over; D001783:Blood Flow Velocity; D004487:Edema / Q000503:physiopathology; D005260:Female; D005263:Femoral Artery / Q000503:physiopathology; D006801:Humans; D006874:Hydrostatic Pressure; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D013924:Thrombophlebitis / Q000503:physiopathology*