Mandibular-morphogenesis gene linked to the H-2 complex in mice.
The shapes of mandibles from mice of a group of H-2 congenic strains are compared to that of their C57BL/6By background strain. One congenic strain carries a passenger gene that evokes an elongation of the dorsal reach of the condylar process as does an H-2 recombinant congenic strain derived from it. Two other independently derived H-2 congenic strains do not carry such a gene. This indicates that the effective gene resides outside of and on the centromeric side of the H-2 complex on chromosome 17. Reiterated tests demonstrate the reproducibility of this type of genetic analysis.
D000818:Animals; D003433:Crosses, Genetic; D005796:Genes; D008040:Genetic Linkage; D006183:H-2 Antigens / Q000235:genetics; D008285:Major Histocompatibility Complex; D008334:Mandible / Q000033:anatomy & histology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D009024:Morphogenesis; D013045:Species Specificity
D006183:H-2 Antigens