title: [Characteristics of the mechanisms of the immune response in typhoid fever and the bacterial carrier state].
abstract: During the acute period of typhoid fever, as well as in the early and, partially, late convalescence periods, a considerable increase in the level of T-lymphocytes and their helper activity and, in some cases, in the number of B- and D-cells and the populations of neutrophils with receptors for C3 and Fc IgG was observed. In chronic carriers immune shifts of a different character have been recorded: an increase in suppressor activity and a decrease in the number of the above-mentioned neutrophils. These data prompt the use of immunological criteria for the prediction of chronic carrier state in typhoid fever.
mesh_terms: D000328:Adult; D000937:Antigen-Antibody Reactions; D001402:B-Lymphocytes / Q000276:immunology; D002353:Carrier State / Q000276:immunology*; D003289:Convalescence; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D009504:Neutrophils / Q000276:immunology; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology; D014435:Typhoid Fever / Q000276:immunology*
chemical_list: D007136:Immunoglobulins
vernacular_title: Osobennosti mekhanizmov immunnogo otveta pri briushnom tife i bakterionositel'stve.