[Significance of the oral NBT-PABA test for the diagnosis of chronic pancreatitis].
The documentation of exocrine pancreatic insufficiency is important for the clinical diagnosis of chronic pancreatitis. The NBT-PABA test (Bentiromide test) depends on the cleavage peptide NBT-PABA by chymotrypsin and the quantitation of released PABA in serum or urine. The sensitivity of the oral NBT-PABA test is nearly as high as that of the much more demanding secretin-CCK test and the specificity is excellent as well. The NBT-PABA test is a simple and valuable aid for the clinical diagnosis and follow-up of patients with chronic pancreatitis.
D010129:4-Aminobenzoic Acid; D000284:Administration, Oral; D062365:Aminobenzoates; D002908:Chronic Disease; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis; D006801:Humans; D010186:Pancreatic Function Tests; D010195:Pancreatitis / Q000175:diagnosis*; D062366:para-Aminobenzoates
D062365:Aminobenzoates; D062366:para-Aminobenzoates; C006717:bentiromide; D010129:4-Aminobenzoic Acid
Die Bedeutung des oralen NBT-PABA-Tests für die Diagnose der chronischen Pankreatitis.