Complex translocation t(8;12;14) in a cell line derived from a child with nonendemic Burkitt-type acute lymphoblastic leukemia.
A cell line is described with a typical Burkitt lymphoma (BL) marker 14q+ due to the classical reciprocal translocation between chromosome #8 and #14 with breakpoints at 8q24.1 and 14q32.3. In addition, an interstitial piece from the long arm of 12(q24.1-q24.3) is inserted at the site of the exchange on chromosome #8, proximal to 14q32.3.
D001402:B-Lymphocytes; D002051:Burkitt Lymphoma / Q000235:genetics*; D002460:Cell Line; D002648:Child; D002871:Chromosome Banding; D002881:Chromosomes, Human, Pair 12; D002883:Chromosomes, Human, Pair 14; D002898:Chromosomes, Human, Pair 8; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic
D005819:Genetic Markers