title: Clinical, genetic and cytogenetic studies in couples attending an infertility clinic.
abstract: The present study was carried out in order to assess the genetic component in a group of sterile or infertile couples from a latin american population. During a six-year-period, 258 patients were investigated. Sixty two per cent of the cases were studied for sterility and 38% for infertility. It was found that 34% had genetic pathology. In infertile couples the frequency of chromosome abnormalities was 2.8%; when sterility was also considered this frequency was 11.6%. Chromosome variants were found in 11.4% of the sterile patients and in 8.8% of the infertile cases.
mesh_terms: D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D003582:Cytogenetics; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000235:genetics*; D007248:Infertility, Male / Q000209:etiology / Q000235:genetics*; D008297:Male