Serum activity of C1 inactivator in Duchenne-type progressive muscular dystrophy.
We previously found that the level of the immunoreactive activity of C1 inactivator in the plasma Duchenne-type patients with progressive muscular dystrophy was lower than that in normal boys. Therefore, we investigated the level of the C1 inactivator inhibiting activity against C1 esterase in the serum from PMD patients. The mean level of anti-esterase activity of C1 inactivator against C1 esterase in the serum from PMD was 50% lower than that of the control group (P less than 0.05).
D000293:Adolescent; D000328:Adult; D002648:Child; D003166:Complement Activating Enzymes / Q000378:metabolism*; D003174:Complement C1 Inactivator Proteins / Q000032:analysis*; D003173:Complement C1s / Q000378:metabolism*; D006801:Humans; D008297:Male; D009136:Muscular Dystrophies / Q000097:blood* / Q000201:enzymology; D012016:Reference Values
D003174:Complement C1 Inactivator Proteins; D003166:Complement Activating Enzymes; D003173:Complement C1s