A radioprotector: cysteamine, inhibits oxygen transport in lipidic membranes.
Spin labeling techniques make possible the observation of oxygen diffusion or concentrations in phospholipid membranes. In such a system, cysteamine, depending upon the molecular cysteamine/DPPC ratio and the pH conditions, inhibits oxygen transport, and this result provides an original explanation for cellular hypoxia after cysteamine administration.
D001692:Biological Transport; D003543:Cysteamine / Q000494:pharmacology*; D008567:Membranes, Artificial; D010100:Oxygen / Q000493:pharmacokinetics*; D010743:Phospholipids; D011837:Radiation-Protective Agents / Q000494:pharmacology*
D008567:Membranes, Artificial; D010743:Phospholipids; D011837:Radiation-Protective Agents; D003543:Cysteamine; D010100:Oxygen