Kinetics of cytotoxic T lymphocytes in stage IV-S neuroblastoma.
The kinetics of cytotoxic T lymphocytes (CTL) in a patient with stage IV-S neuroblastoma were examined for 2 months. CTL were detectable during the preoperative and postoperative periods in this stage IV-S neuroblastoma patient, in spite of the tumor-bearing condition. Furthermore, the patient's mother showed the same level of CTL. This experiment suggests that patients with stage IV-S neuroblastoma have a constantly high level of CTL, and that this immunologic response is predominantly hereditary.
D000310:Adrenal Gland Neoplasms / Q000276:immunology*; D002478:Cells, Cultured; D003429:Cross Reactions; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007376:Interleukin-2 / Q000096:biosynthesis; D008113:Liver Neoplasms / Q000556:secondary; D009447:Neuroblastoma / Q000276:immunology* / Q000556:secondary; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
D007376:Interleukin-2