Colony-stimulating factor-1 induces thromboplastin activity in murine macrophages and human monocytes.
Highly purified colony-stimulating factor-1 induced thromboplastin activity in murine macrophages and human monocytes in vitro. The activity increase was inhibited by cycloheximide and prevented by antibodies to CSF-1.
D000818:Animals; D003115:Colony-Stimulating Factors / Q000276:immunology / Q000494:pharmacology*; D003513:Cycloheximide / Q000494:pharmacology; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology; D007700:Kinetics; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism*; D051379:Mice; D008809:Mice, Inbred C3H; D009000:Monocytes / Q000187:drug effects / Q000378:metabolism*; D010529:Peritoneal Cavity / Q000166:cytology; D011112:Polymyxin B / Q000494:pharmacology; D013925:Thromboplastin / Q000096:biosynthesis*
D003115:Colony-Stimulating Factors; D007106:Immune Sera; D013925:Thromboplastin; D003513:Cycloheximide; D011112:Polymyxin B