Antimicrobial effects of niridazole on Gardnerella vaginalis.
Niridazole, a nitrothiazole derivative, demonstrated powerful antimicrobial activity against 510 clinical isolates of Gardnerella vaginalis tested. MIC's ranged from 0.002 to 1.0 mg/l with MIC50 and MIC90 values of 0.02 and 0.067 mg/l respectively.
D004305:Dose-Response Relationship, Drug; D005260:Female; D006194:Gardnerella vaginalis / Q000187:drug effects*; D006190:Haemophilus / Q000187:drug effects*; D006192:Haemophilus Infections / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009560:Niridazole / Q000494:pharmacology*; D014627:Vaginitis / Q000382:microbiology*
D009560:Niridazole