Epidermal growth factor causes hypocalcemia in sheep.
During iv infusions of epidermal growth factor into sheep, serum calcium concentrations fell, whereas serum magnesium and serum immunoreactive PTH levels increased. Urinary calcium and magnesium decreased significantly. The role of epidermal growth factor in calcium homeostasis is discussed.
D000818:Animals; D002118:Calcium / Q000652:urine; D004815:Epidermal Growth Factor; D006996:Hypocalcemia / Q000139:chemically induced*; D008274:Magnesium / Q000652:urine; D008297:Male; D009919:Orchiectomy; D010281:Parathyroid Hormone / Q000097:blood; D012756:Sheep; D013997:Time Factors
D010281:Parathyroid Hormone; D004815:Epidermal Growth Factor; D008274:Magnesium; D002118:Calcium