Prolactin binding protein in human milk.
Milk samples at day 16 of lactation were from six mothers delivering infants at 28-30 weeks of gestation and six mothers delivering normal full term infants. These early morning samples were used in a prolactin binding assay to determine whether 125I-labelled human prolactin was selectively bound to a soluble protein fraction. After Sephadex G-100 column chromatography, 7 samples contained a protein fraction which bound human prolactin. Binding was not apparent in the remaining 5 samples. Prior binding of maternal prolactin, total binding capacity and differing free prolactin levels may be significant factors responsible for these observations.
D002352:Carrier Proteins / Q000378:metabolism*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007774:Lactation; D008895:Milk, Human / Q000378:metabolism*; D011247:Pregnancy; D011388:Prolactin / Q000378:metabolism*
D002352:Carrier Proteins; C029702:prolactin-binding protein; D011388:Prolactin