Linkage analysis between maturity-onset type diabetes in young people (MODY) and HLA.
Linkage analysis between HLA-A, B, C, D-antigens and maturity-onset diabetes of young people (MODY) was performed in a large kindred including 16 affected members. Close linkage could be excluded. The highest z-value was 0.279 for a recombination fraction of theta = 0.05.
D000328:Adult; D000367:Age Factors; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D006680:HLA Antigens / Q000235:genetics*; D006684:HLA-DR Antigens / Q000235:genetics; D015803:HLA-DR3 Antigen; D015804:HLA-DR4 Antigen; D006801:Humans; D010375:Pedigree
D006680:HLA Antigens; D006684:HLA-DR Antigens; D015803:HLA-DR3 Antigen; D015804:HLA-DR4 Antigen