Intraocular involvement of T and B cell lymphomas.
Six elderly patients with ocular involvement by Non-Hodgkin's lymphoma are reviewed. The characteristic clinical features were a history of fluctuating vision, findings of decreased colour vision, constricted visual fields, vitreous cells and subretinal infiltrates. Fluorescein angiography revealed pigment epithelial abnormalities and attenuated retinal vessels. Non-invasive investigations produced a definite diagnosis in two patients and a presumptive diagnosis in a further three. The ocular involvement was confirmed by vitreous cytology in only one patient: vitreous biopsies in three other patients yielded chronic inflammatory cells and no evidence of lymphoma. The condition responded poorly to steroids but well to radiotherapy.
D000368:Aged; D000369:Aged, 80 and over; D001402:B-Lymphocytes; D003117:Color Vision Defects / Q000209:etiology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology; D013601:T-Lymphocytes; D014786:Vision Disorders / Q000209:etiology*; D014792:Visual Acuity; D014794:Visual Fields