Cytogenetics of Abelson virus-induced malignant lymphoma cell lines in the mouse.
Cytogenetic studies were performed on 11 established murine thymoma or peripheral lymphoma cell lines induced by a thymotropic Abelson virus. In eight cell lines a trisomy 5 was present, whereas, two cell lines had a normal karyotype like fresh tumor cells. In the last cell line a trisomy 11 resulting from a t(5;11) was observed. The origin of this nonrandom chromosome abnormality is briefly discussed.
D000011:Abelson murine leukemia virus; D000818:Animals; D001402:B-Lymphocytes; D002460:Cell Line; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D007621:Karyotyping; D007942:Leukemia, Experimental / Q000235:genetics*; D051379:Mice; D008815:Mice, Inbred Strains