title: Effect of vegetarian diet on serum 1,25-dihydroxyvitamin D concentrations during lactation.
abstract: The effect of maternal diet on serum 1,25-dihydroxyvitamin D has not been determined in human lactation. Serum 1,25-dihydroxyvitamin D, other calcitropic hormones, osteocalcin, and minerals were examined in lactating and nonlactating women consuming a vegetarian or nonvegetarian diet. The vegetarian diet was a macrobiotic diet consisting primarily of whole cereal grains and vegetables; dairy products, eggs, and meats were generally avoided. We tested the thesis that the effect of lactation on serum 1,25-dihydroxyvitamin D is more pronounced in women on vegetarian diets than in those on nonvegetarian diets. Serum 1,25-dihydroxyvitamin D concentrations were significantly higher in lactating women compared with nonlactating women and in vegetarian compared with nonvegetarian women. Among vegetarian women, mean serum 1,25-dihydroxyvitamin D concentrations were 37% higher in the lactating group. For all subjects, serum parathyroid hormone was elevated during lactation compared with nonlactation. Thus, a vegetarian diet appears to be associated with increased serum 1,25-dihydroxyvitamin D during lactation.
mesh_terms: D000328:Adult; D002117:Calcitriol / Q000097:blood*; D002135:Calcium-Binding Proteins / Q000097:blood; D004032:Diet; D014676:Diet, Vegetarian; D005260:Female; D006801:Humans; D007774:Lactation; D008903:Minerals / Q000097:blood; D015675:Osteocalcin; D010281:Parathyroid Hormone / Q000097:blood; D011247:Pregnancy
chemical_list: D002135:Calcium-Binding Proteins; D008903:Minerals; D010281:Parathyroid Hormone; D015675:Osteocalcin; D002117:Calcitriol