Brainstem discharge sites: therapeutic targets for chronic pain.
Optimum mesothalamic targets for therapeutic electrode implants are characterized by (1) spontaneously occurring focal discharges, (2) attenuation of the discharges by electrical stimulation, and (3) stimulation-induced pain relief.
D001933:Brain Stem / Q000503:physiopathology*; D002908:Chronic Disease; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D004569:Electroencephalography; D006801:Humans; D010146:Pain / Q000503:physiopathology; D059408:Pain Management