title: Retrograde air embolization in coronary operations.
abstract: Observations during coronary operations are presented that prove that if the ascending aorta is cross-clamped and suction applied to the left side of the heart or to the aortic root for venting purposes, the pressure rapidly drops in the coronary arterial system and a situation is created in which air may enter through the coronary arteriotomy and pass into the aortic root and the left ventricle. Another mechanism to explain the occurrence of some cases of "iatrogenic" air embolism has also been presented: introduction of air into the ascending aorta while cardioplegic solution is being injected through peripherally attached bypass grafts. Air trapped in these grafts or in the coronary artery itself may propagate proximally as well as distally in the coronary arteries and may reach the aortic root even if the left side of the heart is left unvented. These mechanisms may be responsible for heretofore unexplained cases of "iatrogenic" air embolization. We recommend careful purging of air, which may be present, from the left ventricle and aortic root every time before the aortic cross-clamp is removed during coronary operations.
mesh_terms: D001011:Aorta / Q000601:surgery; D003250:Constriction; D001026:Coronary Artery Bypass; D003331:Coronary Vessels / Q000502:physiology / Q000601:surgery; D004618:Embolism, Air / Q000209:etiology*; D006324:Heart Arrest, Induced; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology*; D011312:Pressure