title: Second malignancies in patients surviving osteosarcoma.
abstract: Sixty-nine patients were identified who had survived for at least 10 years after therapy for ordinary-type intramedullary osteosarcoma and for whom adequate follow-up data were available to determine whether second malignancies had developed. Eight patients (11.6%) had developed second malignant tumors, 5 of whom had died of their second malignancies. Although these figures are higher than those expected for cancer incidence and death rates, the differences are not statistically significant.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000401:mortality / Q000473:pathology*