Influence of ethanol on glutathione level in the blood, liver and kidneys of Rana temporaria L. in the annual cycle.
The effects of single doses (3 g/kg and 9 g/kg) of 35% ethanol, on the glutathione (GSH) contents of the blood, liver and kidneys of Rana temporaria L. were studied in the annual cycle. It was found that the single doses of ethanol generally caused a significant increase of GSH in the blood and liver of males and females of Rana temporaria L. in each period of the annual cycle as compared with the control values. In time, it was found that the same doses of ethanol caused a significant decrease in the GSH content of the kidneys of the male and female Rana temporaria L. during their active land life and a strong increase of this tripeptide during hibernation.
D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005978:Glutathione / Q000097:blood / Q000378:metabolism*; D006605:Hibernation; D007668:Kidney / Q000032:analysis*; D008099:Liver / Q000032:analysis*; D008297:Male; D011896:Rana temporaria; D012737:Sex Factors
D000431:Ethanol; D005978:Glutathione