title: Discriminative conditioning-related slow potential and single-unit responses in the frontal cortex of urethane-anesthetized rats.
abstract: A model is described for obtaining long-term and stable discriminative conditioning-related slow-potential and single-unit responses from the frontal cortex of urethane-anesthetized rats. Responses were recorded and analyzed to reinforced (rewarding medial forebrain bundle stimulation) and non-reinforced tone cues. In the present study, cortical event-related slow potentials provided an adequate index of the level of discriminative conditioning. Single-unit response patterns are described for 57 neurons which demonstrated a discriminative response to either the reinforced or non-reinforced tone cue.
mesh_terms: D000768:Anesthesia, General; D000818:Animals; D003214:Conditioning, Classical / Q000502:physiology*; D004193:Discrimination Learning / Q000502:physiology*; D004558:Electric Stimulation; D005625:Frontal Lobe / Q000502:physiology*; D008297:Male; D008474:Medial Forebrain Bundle / Q000502:physiology; D010897:Pitch Discrimination / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013016:Sound; D014520:Urethane
chemical_list: D014520:Urethane