title: Hemorrhagic complications of piperacillin therapy.
abstract: Clinically significant hemorrhage associated with extended spectrum anti-Pseudomonas penicillins is uncommon. We describe 2 patients with bleeding complications owing to piperacillin. In addition, we review the incidence and mechanism of this adverse reaction, and make suggestions for the management of these patients.
mesh_terms: D001780:Blood Coagulation Tests; D001791:Blood Platelet Disorders / Q000139:chemically induced*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010878:Piperacillin / Q000009:adverse effects* / Q000627:therapeutic use; D011292:Premedication
chemical_list: D010878:Piperacillin