Effects of NaF and SnF2 on growth, acid and glucan production of several oral streptococci.
The effects of low concentrations of these fluorides on Streptococcus sobrinus, Streptococcus mutans, Streptococcus salivarius, Streptococcus mitior and Streptococcus sanguis were investigated. Without fluoride, mutans streptococci (Strep. mutans and Strep. sobrinus) produced more acid than the other strains; both fluorides reduced acid production in all strains. NaF had little effect on growth; SnF2 decreased growth in all strains, most evidently in the Strep. mutans. In all growth conditions, Strep. sobrinus produced the most alkali-soluble glucan. Both fluorides enhanced alkali-soluble glucan production in mutans streptococci while only SnF2 enhanced this in the other streptococci.
D004269:DNA, Bacterial / Q000187:drug effects; D005459:Fluorides / Q000494:pharmacology*; D005936:Glucans / Q000378:metabolism; D006801:Humans; D012969:Sodium Fluoride / Q000494:pharmacology*; D013291:Streptococcus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D013295:Streptococcus mutans / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D014002:Tin Fluorides / Q000494:pharmacology*
D004269:DNA, Bacterial; D005936:Glucans; D014002:Tin Fluorides; D012969:Sodium Fluoride; D005459:Fluorides