title: Esterase-25 (Es-25): identification and characterization of a new kidney arylesterase of the house mouse, genetically linked to Ly-18 on chromosome 12.
abstract: Genetic variation of a codominantly inherited kidney esterase, designated ES-25, has been discovered in the house mouse using disc electrophoresis. The ES-25A phenotype was found in A strains, AKR, and BALB/c. ES-25B was found in C57BL strains and several other laboratory strains. The enzyme was shown to be controlled by a presumed structural locus, Es-25. The high concordance in 48 RI strains of Es-25 with Ly-18 indicated the location of Es-25 on chromosome 12. The gene order Es-25-Ly-18-D12Nyul-Pre-1 was proposed.
mesh_terms: D000818:Animals; D002265:Carboxylic Ester Hydrolases / Q000032:analysis* / Q000235:genetics; D002874:Chromosome Mapping; D004591:Electrophoresis, Polyacrylamide Gel; D008040:Genetic Linkage; D005819:Genetic Markers; D007668:Kidney / Q000201:enzymology*; D051379:Mice; D008815:Mice, Inbred Strains; D010641:Phenotype
chemical_list: D005819:Genetic Markers; D002265:Carboxylic Ester Hydrolases; C019734:arylesterase