Phylogenetic studies on lymphokines. Fish lymphocytes respond to human IL-1 and epithelial cells produce an IL-1 like factor.
The results obtained indicate, that catfish peripheral blood lymphocytes recognize and respond to human IL-1. The second part of this report is dealing with a substance produced by carp epidermal cells with functional similarities to mammalian IL-1.
D000818:Animals; D002347:Carps / Q000097:blood / Q000378:metabolism; D002460:Cell Line; D002645:Chickens; D004847:Epithelial Cells; D005399:Fishes / Q000097:blood*; D006801:Humans; D007375:Interleukin-1 / Q000096:biosynthesis / Q000494:pharmacology*; D008214:Lymphocytes / Q000187:drug effects*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010802:Phylogeny; D011863:Radioimmunoassay; D013601:T-Lymphocytes / Q000187:drug effects; D013929:Thromboxane B2 / Q000032:analysis
D007375:Interleukin-1; D013929:Thromboxane B2