Assignment of the TCP1 locus to the long arm of human chromosome 6 by in situ hybridization.
TCP1, the human homolog of the Tcp-1 locus in the mouse, which is part of the murine t complex and codes for an abundant testicular germ-cell protein, has been mapped within the human genome by in situ hybridization. Using a cDNA probe for TCP1, pB1.4 hum, we assigned TCP1 to human chromosome region 6q23----qter, with the most likely localization being 6q25----q27.
D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002896:Chromosomes, Human, Pair 6; D004247:DNA / Q000235:genetics; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D007621:Karyotyping; D051379:Mice; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; D009693:Nucleic Acid Hybridization; D011506:Proteins / Q000235:genetics*; D013045:Species Specificity; D013735:Testicular Hormones / Q000235:genetics*; D044767:Ubiquitin-Protein Ligases; D056427:t-Complex Genome Region
D005819:Genetic Markers; D047908:Intracellular Signaling Peptides and Proteins; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; D011506:Proteins; D013735:Testicular Hormones; D004247:DNA; C116196:PPP1R11 protein, human; D044767:Ubiquitin-Protein Ligases