[Comparative analysis of the cell composition of the infiltrate in malignant lymphoma of the skin].
Electron microscopy was used to investigate skin biopsy specimens in 20 patients with different clinicomorphological types of T-cell skin lymphomas (TCSL) over time. At early stages prognosis was based on the level of macrophage and fibroblast differentiation in the infiltrate: the more mature nonlymphoid elements were, the graver was a course of disease. Therefore patch and papulous variants of primary cutaneous reticulosis (atrophic parapsoriasis and mycosis fungoides with follicular mucinosis) were classified as TCSL of a low and medium degree of malignancy. The classical and beheaded forms of mycosis fungoides were attributed to a medium and high degree of malignancy.
D001706:Biopsy; D005347:Fibroblasts / Q000648:ultrastructure; D006801:Humans; D008223:Lymphoma / Q000473:pathology* / Q000648:ultrastructure; D008264:Macrophages / Q000648:ultrastructure; D009182:Mycosis Fungoides / Q000473:pathology / Q000648:ultrastructure; D009367:Neoplasm Staging; D010267:Parapsoriasis / Q000473:pathology; D011379:Prognosis; D012867:Skin / Q000473:pathology / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D013601:T-Lymphocytes
Sravnitel'nyĭ analiz kletochnogo sostava infiltrata zlokachestvennykh limfom kozhi.