Azlocillin and the immune response in intensive care.
The authors have followed the course of the immunological cellular and humoral parameters in 12 patients in the Intensive Care Unit at the University Polyclinic of Messina having grave infections of the respiratory apparatus, for which an antibiotic therapy with azlocillin, semisynthetic penicillin was carried out; all this with the aim of pointing out any possible interferences with the already precarious immune system in such patients. The results obtained seem to exclude any immunodepressing activity by the molecule.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001390:Azlocillin / Q000494:pharmacology*; D001402:B-Lymphocytes / Q000187:drug effects; D003422:Critical Care; D003428:Cross Infection / Q000276:immunology; D005260:Female; D006801:Humans; D007109:Immunity / Q000187:drug effects*; D007136:Immunoglobulins / Q000378:metabolism; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects
D007136:Immunoglobulins; D001390:Azlocillin