Herpes zoster ophthalmicus.
The incidence and severity of herpes zoster ophthalmicus have increased because of the growing number of immunocompromised patients. Uveitis and keratitis are the most common inflammatory complications. Corneal exposure from scarring and contraction of the upper lid may require reconstructive plastic surgery. Preliminary studies of oral acyclovir, specifically targeted at preventing ocular complications, are encouraging.
D000212:Acyclovir / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003236:Conjunctivitis, Viral / Q000209:etiology; D005141:Eyelid Diseases / Q000209:etiology; D005260:Female; D006563:Herpes Zoster Ophthalmicus / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D007108:Immune Tolerance; D007634:Keratitis / Q000209:etiology; D008297:Male; D009916:Orbital Diseases / Q000209:etiology; D012164:Retinal Diseases / Q000209:etiology; D014481:United States; D014606:Uveitis, Anterior / Q000209:etiology
D000998:Antiviral Agents; D000212:Acyclovir