Adoptive transfer of allergic encephalomyelitis by inoculation of cells into lymph nodes.
Experimental allergic encephalomyelitis can be transferred passively by lymph node cells from actively immunized donor rats to immunologically naive syngeneic recipients. In the present work, passive transfer was accomplished by direct inoculation of donor cells into the recipient's lymph node, and this route was more effective than the conventional intravenous or intraperitoneal routes.
D000818:Animals; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology*; D007116:Immunization, Passive / Q000379:methods*; D007267:Injections; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D008198:Lymph Nodes / Q000166:cytology* / Q000276:immunology; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D014001:Tin / Q000494:pharmacology; D014765:Viral Vaccines / Q000008:administration & dosage
D014765:Viral Vaccines; D014001:Tin