Streptococcal protein G: a sensitive tool for detection of antibodies to human immunodeficiency virus proteins in Western blot analysis.
Protein G is a cell wall protein of group C and G streptococci which binds human IgG antibodies of all four subclasses with high affinity. This property of the molecule was utilized to develop a sensitive Western blot assay to detect antibodies against HIV proteins in patient sera.
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D001426:Bacterial Proteins / Q000276:immunology*; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies; D006679:HIV Seropositivity / Q000175:diagnosis*; D006801:Humans; D007118:Immunoassay; D007074:Immunoglobulin G / Q000276:immunology*; D008297:Male; D014764:Viral Proteins / Q000276:immunology
D000914:Antibodies, Viral; D001426:Bacterial Proteins; D015483:HIV Antibodies; C034284:IgG Fc-binding protein, Streptococcus; D007074:Immunoglobulin G; D014764:Viral Proteins