title: [Diagnosis of the recurrence of epithelial ovarian cancer with the tumor marker CA 125].
abstract: Aim of this study was to evaluate the significance of serum CA 125 levels in our ovarian cancer follow-up programme for earlier detection of recurrent or progressive disease. 43 out of 133 patients developed tumour progression, whereby 42 (97.7%) showed positive serum CA 125 levels and in 25 patients (58.2%) the increase in tumour marker preceded the first clinical signs by 4 to 36 weeks. The mean lead time was 14.2 weeks. Hence, determination of serum CA 125 should be mandatory in the follow-up investigation of women with epithelial ovarian carcinomas.
mesh_terms: D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000628:therapy; D010053:Ovary / Q000473:pathology
chemical_list: D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate
vernacular_title: Rezidivdiagnostik beim epithelialen Ovarialkarzinom mit dem Tumormarker CA 125.