VLDL cholesterol and VLDL apolipoprotein B. Preliminary cross-sectional data of the prospective epidemiological study of company employees in Westphalia.
VLDL cholesterol concentrations were determined in 1641 male and 608 female and VLDL apolipoprotein B concentrations in 505 male and 211 female company employees in Westphalia aged 17-70 years. VLDL cholesterol and VLDL apolipoprotein B values were found to be distributed with positive skew in both sexes but were higher in men than in women (median in men: VLDL cholesterol 0.30 mmol/l, VLDL apolipoprotein B 0.066 g/l, median in women: VLDL cholesterol 0.18 mmol/l, VLDL apolipoprotein B 0.047 g/l). In males VLDL cholesterol and VLDL apolipoprotein B were closely correlated to each other (r = 0.757) as well as to triacylglycerols (VLDL cholesterol: r = 0.673, VLDL apolipoprotein B: r = -0.419). In females these observed correlations were weaker. The VLDL cholesterol/VLDL apolipoprotein B ratio was also higher in men (median 4.28 mmol/g) than in women (median 3.15 mmol/g). The ratio correlated to triacylglycerols (men: r = 0.591, women: r = 0.321). The results suggest that the composition of VLDL may be related to triacylglycerols in serum.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001055:Apolipoproteins B / Q000097:blood*; D002784:Cholesterol / Q000097:blood*; D015243:Cholesterol, VLDL; D004812:Epidemiologic Methods; D005260:Female; D005860:Germany, West; D006801:Humans; D008079:Lipoproteins, VLDL / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood
D001055:Apolipoproteins B; D015243:Cholesterol, VLDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides; D002784:Cholesterol