title: Primary lesions of bone in the 1st decade of life: retrospective survey of biopsy results.
abstract: Primary bone tumors in early childhood are uncommon, and the incidence of malignancy in the 1st decade of life has not been evaluated adequately in the literature. For this reason, we conducted a retrospective review of 268 biopsies of the bone in 249 patients who were less than 10 years of age. Benign tumors were found much more frequently than malignant lesions. Osteochondroma and histiocytosis X were the most common lesions. The incidence of several benign lesions in our series was deceptively low, as many lesions showed typical radiographic findings, precluding the need for biopsy or excision. Of 41 primary malignant bone tumors, Ewing sarcoma was slightly more common than osteosarcoma. The rib was the most frequent site of the former; the distal femur, of the latter.
mesh_terms: D001845:Bone Cysts / Q000000981:diagnostic imaging / Q000473:pathology; D001847:Bone Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002804:Chondroblastoma / Q000000981:diagnostic imaging / Q000473:pathology; D002812:Chondroma / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005354:Fibrosarcoma / Q000000981:diagnostic imaging / Q000473:pathology; D005357:Fibrous Dysplasia of Bone / Q000000981:diagnostic imaging / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000000981:diagnostic imaging / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D010017:Osteoma, Osteoid / Q000000981:diagnostic imaging / Q000473:pathology; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D012512:Sarcoma, Ewing / Q000000981:diagnostic imaging / Q000473:pathology