title: Outcome of treatment in 35 cases of guttural pouch mycosis.
abstract: This paper describes the outcome of treatment of 30 cases of guttural pouch mycosis by ligation of the internal carotid artery on the cardiac side of the lesion and lavage of the affected pouch with natamycin. Twenty-three horses recovered fully following this treatment while laryngeal hemiplegia persisted in one case and slight dysphagia caused by pharyngeal hemiplegia in another. The remaining five horses died or were destroyed. Five horses with guttural pouch mycosis, which had shown no epistaxis but had pharyngeal hemiplegia, were treated by topical natamycin alone. Only two of these survived, of which one remained slightly dysphagic. Ligation of the internal carotid artery of the cardiac side of the lesion is an effective means of reducing the chance of fatal epistaxis in cases of guttural pouch mycosis. Some cases of pharyngeal hemiplegia can make a complete recovery although it may take 12 to 18 months.
mesh_terms: D000287:Administration, Topical; D000818:Animals; D002343:Carotid Artery, Internal / Q000601:surgery*; D005064:Eustachian Tube; D005260:Female; D006734:Horse Diseases / Q000601:surgery / Q000628:therapy*; D006736:Horses; D008026:Ligation / Q000662:veterinary; D008297:Male; D009181:Mycoses / Q000601:surgery / Q000628:therapy / Q000662:veterinary*; D010866:Natamycin / Q000008:administration & dosage / Q000627:therapeutic use; D010038:Otorhinolaryngologic Diseases / Q000601:surgery / Q000628:therapy / Q000662:veterinary*
chemical_list: D010866:Natamycin