[The immunological role of carotenoids in the prevention of cancer].
Epidemiological studies have suggested that the intake of green-yellow vegetables decrease the risk of cancer. Vitamin A, which is abundantly present in green-yellow vegetables in the form of provitamin A, was demonstrated to inhibit chemical and viral-carcinogenesis in experimental animals. However, little is known about the mechanism of anti-carcinogenic effect of vitamin A. Our data seem to support a hypothesis that vitamin A may contribute to the prevention of cancer by augmenting an immunosurveillance system. We found that vitamin A and provitamin A, beta-carotene, enhanced tumor immunity using a syngeneic murine tumor system.
D000818:Animals; D002338:Carotenoids / Q000008:administration & dosage*; D002455:Cell Division; D004032:Diet; D008114:Liver Neoplasms, Experimental / Q000276:immunology / Q000517:prevention & control; D051379:Mice; D009374:Neoplasms, Experimental / Q000276:immunology / Q000473:pathology / Q000517:prevention & control*; D013601:T-Lymphocytes / Q000276:immunology; D014675:Vegetables
D002338:Carotenoids