title: Rapid determination of five coagulation parameters in one sample with a centrifugal analyzer.
abstract: Spectrophotometric clotting assays using chromogenic substrates were adapted for use in a routine laboratory batch analyzer. Contrary to another described method the same plasma dilution can be used for each of the different coagulation parameters. Optimal assay conditions were determined. The within- and between-assay variation, the intraindividual variation during 1 day and from month-to-month were determined; the chromogenic assay was compared to a clotting assay. No significant difference (p less than 0.01) between manual and automated methods was found.
mesh_terms: D000990:Antithrombin III / Q000032:analysis*; D001780:Blood Coagulation Tests / Q000295:instrumentation / Q000379:methods; D005170:Factor X / Q000032:analysis*; D015951:Factor Xa; D006801:Humans; D010958:Plasminogen / Q000032:analysis*; D012697:Serine Endopeptidases / Q000032:analysis*; D000979:alpha-2-Antiplasmin / Q000032:analysis*
chemical_list: D000979:alpha-2-Antiplasmin; D000990:Antithrombin III; D005170:Factor X; D010958:Plasminogen; D012697:Serine Endopeptidases; D015951:Factor Xa