Late thrombolysis with intracoronary streptokinase after myocardial infarction.
This patient had a myocardial infarction 4 years after coronary bypass grafting. Catheterization 1 month later revealed occlusion of the graft to the posterior descending by what appeared to be a clot. On each of 3 successive days, infusion of streptokinase accomplished recanalization of the graft. After the third treatment, he showed marked symptomatic improvement. Recanalization may be successful as late as 1 month after occlusion and repeated infusions of streptokinase over a period of days can be carried out safely and without loss of effectiveness.
D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000188:drug therapy*; D003331:Coronary Vessels; D006083:Graft Occlusion, Vascular / Q000188:drug therapy*; D006801:Humans; D007263:Infusions, Parenteral; D007267:Injections; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications*; D012501:Saphenous Vein / Q000637:transplantation*; D013300:Streptokinase / Q000008:administration & dosage / Q000627:therapeutic use*
D013300:Streptokinase