[Production of interleukin-2 by peripheral blood lymphocytes from patients with soft tissue sarcomas].
Interleukin-2 (IL-2) production of phytohemagglutinin-stimulated peripheral blood lymphocytes (PBL) was studied in 9 healthy subjects and 19 patients with soft tissue sarcomas. Mean IL-2 production by PBL in 19 patients was significantly diminished as compared with the control. Surgery leads to an increase of IL-2 production, however, the levels observed in the control do not restore completely.
D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism*; D012509:Sarcoma / Q000097:blood*; D012983:Soft Tissue Neoplasms / Q000097:blood*
D007376:Interleukin-2
Produktsiia interleĭkina-2 limfotsitami perifericheskoĭ krovi bol'nykh sarkomami miagkikh tkaneĭ.