[Assessment of the immune status of chronic bronchitis patients in the remission phase during prophylactic treatment with levamisole and staphylococcal vaccine].
The work presents the results of the study of the immune status in 18 patients with chronic bronchitis at the stage of remission, subjected to prolonged prophylactic treatment with the inhalations of levamisole solution, and in 16 patients receiving the inhalations of staphylococcal vaccine. These results indicate that the inhalations of levamisole have proved to be more effective than the inhalations of staphylococcal vaccine. In patients treated with levamisole an essential decrease in the ratio of theophylline-resistant to theophylline-sensitive E-rosette-forming lymphocytes has been noted. The determination of the sensitivity of lymphocytes and neutrophils to incubation with levamisole by means of the rosette-formation test makes it possible to prognosticate, taking into account the initial level of spontaneous E-rosette formation of these cells, the effectiveness of the prophylactic treatment of patients with chronic bronchitis. The determination of the sensitivity of the cells to incubation with staphylococcal toxoid is ineffective for the prognostication of the result of the treatment of such patients with staphylococcal vaccine.
D000336:Aerosols; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D001991:Bronchitis / Q000276:immunology* / Q000517:prevention & control; D002908:Chronic Disease; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology; D011379:Prognosis; D013209:Staphylococcal Vaccines / Q000627:therapeutic use*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013997:Time Factors
D000336:Aerosols; D013209:Staphylococcal Vaccines; D007978:Levamisole
Otsenka immunnogo statusa u bol'nykh khronicheskim bronkhitom v faze remissii v protsesse profilakticheskogo lecheniia levamizolom i stafilokokkovoĭ vaktsinoĭ.