Effective propagation of various type D retroviruses in human lymphoblastoid Raji cells.
Type D retroviruses belong to viruses which often have a low titer in virus-reproducing cell-systems. In search of better conditions for virus propagation, Raji cells (an EBV-genome carrying human B-cell line) were infected with different isolates of type D retroviruses. as demonstrated by electron microscopy all of the viruses showed a very good and stable virus production during long term cultivation on Raji cells.
D001402:B-Lymphocytes / Q000382:microbiology*; D002460:Cell Line; D002472:Cell Transformation, Viral; D006801:Humans; D008854:Microscopy, Electron; D012190:Retroviridae / Q000254:growth & development* / Q000302:isolation & purification / Q000648:ultrastructure; D014779:Virus Replication