Altered immune reactivity of mice born from mothers treated with ampicillin during gestation.
The cellular and humoral immune responses of 30-day-old mice born from mothers treated with ampicillin during pregnancy were studied. A lowering of cellular immunity, accompanied by a decrease in T lymphocyte percentage in lymph nodes, and an increase of humoral immune response were observed.
D000667:Ampicillin / Q000633:toxicity*; D000818:Animals; D005260:Female; D006386:Hemagglutination Tests; D007109:Immunity / Q000187:drug effects*; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology; D051379:Mice; D008809:Mice, Inbred C3H; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D013601:T-Lymphocytes / Q000276:immunology; D013997:Time Factors
D000667:Ampicillin