Clonal chromosome aberrations in a case of cutaneous T-cell lymphoma.
Cytogenetic analysis was performed on peripheral blood and on a skin infiltration from a patient with cutaneous T-cell lymphoma. The blood cells revealed no chromosome abnormalities; whereas, besides normal cells, the skin lesion yielded on aberrant clone with the following abnormalities: trisomies 8 and 17, a deletion of the short arm of chromosome 11, and formation of one marker chromosome with possible involvement of chromosome #14.
D000368:Aged; D002869:Chromosome Aberrations; D002901:Chromosomes, Human, 13-15; D002906:Chromosomes, Human, 6-12 and X; D002999:Clone Cells; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008223:Lymphoma / Q000235:genetics*; D008297:Male; D009857:Oncogenes; D012878:Skin Neoplasms / Q000235:genetics*; D013601:T-Lymphocytes
D005819:Genetic Markers