title: Superior sagittal sinus thrombosis: assessment with Tc-99m labeled red blood cells.
abstract: The diagnostic value of scintigraphy with technetium-99m labeled red blood cells (Tc-RBC) was assessed in 19 patients with clinical suggestion of superior sagittal sinus thrombosis (SSST). Comparison of Tc-RBC static images with dynamic flow studies in the brain showed a sensitivity of 100%, specificity of 86%, and accuracy of 94% for static studies and values of 87%, 20%, and 61%, respectively, for the flow studies. Tc-RBC scintigraphy enables direct visualization of the integrity of the superior sagittal sinus, whereas CT scanning shows various but nonspecific changes in the brain associated with SSST. Single-photon emission CT study using Tc-RBC, performed in six patients, appears to have potential in the diagnosis of SSST, allowing separation of vascular structures that are superimposed on the superior sagittal sinus in planar scintigraphy study.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001930:Brain Injuries / Q000150:complications; D001932:Brain Neoplasms / Q000150:complications; D002648:Child; D003951:Diagnostic Errors; D004912:Erythrocytes; D005260:Female; D006801:Humans; D007938:Leukemia / Q000150:complications; D008297:Male; D008579:Meningioma / Q000150:complications; D008875:Middle Aged; D012851:Sinus Thrombosis, Intracranial / Q000000981:diagnostic imaging* / Q000209:etiology; D013667:Technetium; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
chemical_list: D013667:Technetium