Effect of food on enoxacin absorption.
Fifteen subjects received a single 400-mg oral dose of enoxacin in the fasting state and after carbohydrate and high-fat meals. The carbohydrate meal delayed the time to peak enoxacin concentration in plasma by an average of 0.92 h. The extent of enoxacin absorption was not altered by food.
D000284:Administration, Oral; D004040:Dietary Carbohydrates / Q000494:pharmacology; D004041:Dietary Fats / Q000494:pharmacology; D015365:Enoxacin; D005502:Food; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects; D007700:Kinetics; D009287:Naphthyridines / Q000008:administration & dosage / Q000378:metabolism*
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D009287:Naphthyridines; D015365:Enoxacin