title: Effects of acid-base status and fluoride on the composition of the mineral in developing enamel and dentine in the dog.
abstract: Developing molar teeth of the dog were sectioned, embedded in copper containing polymethyl methacrylate, polished and their Ca/P and Ca/Na molar ratios investigated with the electron microprobe. The teeth were obtained at 30 days from 9 pups fed regimes of different acid-base status with or without fluoride supplementation from birth to sacrifice at 30 days. No clear trends in their Ca/P or Ca/Na ratios with variation in the diet were observed. However, evaluation of the Ca/P ratio of the enamel as a function of depth revealed that this ratio was 0.80 +/- 0.15 at the mineralization front. This suggests that in enamel brushite rather than octacalcium phosphate is the precursor phase of the mineral.
mesh_terms: D000138:Acidosis / Q000378:metabolism*; D000471:Alkalosis / Q000378:metabolism*; D000818:Animals; D002118:Calcium / Q000032:analysis; D002130:Calcium Phosphates / Q000032:analysis; D003743:Dental Enamel / Q000032:analysis*; D003804:Dentin / Q000032:analysis*; D004285:Dogs; D005459:Fluorides / Q000008:administration & dosage / Q000494:pharmacology*; D008903:Minerals / Q000032:analysis*; D009805:Odontogenesis; D010758:Phosphorus / Q000032:analysis; D012964:Sodium / Q000032:analysis; D014074:Tooth Calcification
chemical_list: D002130:Calcium Phosphates; D008903:Minerals; D010758:Phosphorus; D012964:Sodium; C494366:calcium phosphate, dibasic, dihydrate; D005459:Fluorides; D002118:Calcium