Spontaneous migration and chemotactic activity of neutrophil polymorphonuclear leukocytes in recurrent aphthous ulceration.
Chemotactic activity and spontaneous migration under agarose were assessed for peripheral blood neutrophil polymorphonuclear leukocytes from 22 patients with minor recurrent aphthous ulceration and 22 control subjects. The peptide N-formyl-L-methionyl-L-leucyl-L-phenylalanine was used as the standard chemotactic stimulus. Under the conditions of this study, no significant differences in either chemotaxis or spontaneous migration were evident between neutrophils from the patient and control groups.
D000328:Adult; D000368:Aged; D002465:Cell Movement; D002634:Chemotaxis, Leukocyte; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology / Q000502:physiology*; D012008:Recurrence; D013281:Stomatitis, Aphthous / Q000097:blood* / Q000276:immunology / Q000503:physiopathology