title: Single dose of ornidazole in the treatment of bacterial vaginosis.
abstract: Bacterial vaginosis is the most common cause of excessive and foul smelling vaginal discharge. In the group of 24 women, the diagnosis was based on increased vaginal discharge, positive KOH-test, and detection of clue cells in the wet smear. In the microbiological isolation, Gardnerella vaginalis was also observed in 20 subjects and mixed anaerobic flora in all the 24 subjects. A single dose of 1.5 g of ornidazole was given. Posttreatment control was performed 7 to 28 days later. Gardnerella vaginalis was present in 2 (cure rate 90%) and anaerobes in 4 subjects (cure rate 83%). Subjective improvement occurred in 96% of patients. Side effects, the most common of them being dizziness, after ornidazole treatment were observed by 17 (71%) of subjects.
mesh_terms: D000328:Adult; D001421:Bacteria, Anaerobic / Q000302:isolation & purification; D001424:Bacterial Infections / Q000188:drug therapy*; D005260:Female; D006194:Gardnerella vaginalis / Q000302:isolation & purification; D006192:Haemophilus Infections / Q000188:drug therapy*; D006801:Humans; D009593:Nitroimidazoles / Q000627:therapeutic use*; D009950:Ornidazole / Q000009:adverse effects / Q000627:therapeutic use*; D014623:Vaginal Diseases / Q000188:drug therapy*
chemical_list: D009593:Nitroimidazoles; D009950:Ornidazole