[Long-term treatment and clinical evaluation of enoxacin in complicated urinary tract infections].
Enoxacin (ENX) was used in the treatment of 16 patients with complicated urinary tract infections. ENX was orally administered 600 mg three times a day for 14--32 days. Clinical results evaluated according to the criteria of UTI committee were excellent in 6 cases, moderate in 3 cases and poor in 6 cases. The overall efficacy rate was 60.0%. Two moderate cases at 5 days showed excellent results at 14 days. Twelve out of 18 bacteriological strains were eradicated, with the elimination rate of 66.7%. As side effects, slight constipation occurred in one patient, and he was treated with purgatives. Photoallergic eruptions occurred in one of the 16 patients. He was treated with an antihistaminic agent and soon recovered.
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000892:Anti-Infective Agents, Urinary / Q000008:administration & dosage / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D004341:Drug Evaluation; D015365:Enoxacin; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009287:Naphthyridines / Q000008:administration & dosage / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D000892:Anti-Infective Agents, Urinary; D009287:Naphthyridines; D015365:Enoxacin