[Ceftriaxone in the therapy of infections of the lower respiratory tract: comparison with cefotaxime].
20 patients suffering from severe lower respiratory tract infections were included in the study. 10 patients were given ceftriaxone (1-2 g/day) and the other 10 cefotaxime (2-4 g/day) for a week. The results of microbiological findings and both local and systemic tolerance were found to be similar for both drugs. This indicates that 7-14 g of ceftriaxone and 14-28 g of cefotaxime are equivalent quantities in the treatment of severe respiratory tract infections.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000188:drug therapy; D002439:Cefotaxime / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D004361:Drug Tolerance; D006193:Haemophilus influenzae / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D008875:Middle Aged; D011014:Pneumonia / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification; D013296:Streptococcus pneumoniae / Q000187:drug effects / Q000302:isolation & purification
D002443:Ceftriaxone; D002439:Cefotaxime
Il ceftriaxone nella terapia di infezioni delle basse vie respiratorie: confronto con cefotaxime.