[Metabolism of extracellular adenine nucleotides and adenosine uptake by rat thymocytes; the effect of concanavalin A].
Thymocytes under cultivation conditions are established to catabolyze rapidly extracellular ATP and AMP which do not penetrate through the plasma membrane. Thymocytes uptake adenosine produced from adenosine nucleotides. Concanavalin A inhibits the extracellular hydrolysis of AMP and adenosine uptake by thymocytes.
D000227:Adenine Nucleotides / Q000378:metabolism*; D000241:Adenosine / Q000378:metabolism*; D000249:Adenosine Monophosphate / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology*; D003864:Depression, Chemical; D006868:Hydrolysis; D007700:Kinetics; D008213:Lymphocyte Activation; D051381:Rats; D011919:Rats, Inbred Strains; D013601:T-Lymphocytes / Q000378:metabolism*
D000227:Adenine Nucleotides; D003208:Concanavalin A; D000249:Adenosine Monophosphate; D000255:Adenosine Triphosphate; D000241:Adenosine
Metabolizm vnekletochnykh adeninnukleotidov i pogloshchenie adenozina timotsitami krysy; vliianie konkanavalina A.