The electroretinographic characteristics of congenital tritan defects.
Electroretinographic studies were performed in three congenital tritanopic subjects in a single pedigree. The b-waves were recorded in the presence of white and intense yellow adaptation in response to 16 monochromatic light stimuli. Compared with the response of normal subjects, a marked reduction or a lack of the blue cone responses was clearly shown in the spectral response patterns of tritanopes. Electroretinograms elicited by strong white stimulation or xenon flashes showed negative responses (a-waves larger than b-waves) with normal rod function in each tritanopic subject. This finding points to abnormalities of red cone and green cone function as well in tritanopes.
D003116:Color; D003117:Color Vision Defects / Q000151:congenital* / Q000235:genetics / Q000503:physiopathology; D004596:Electroretinography; D006801:Humans; D010375:Pedigree; D010775:Photic Stimulation / Q000379:methods