title: Production of immunoglobulin M (IgM) autoantibodies to IgG in rabbits inoculated with Mycoplasma salivarium cells grown in medium supplemented with rabbit serum.
abstract: Mycoplasma salivarium cells propagated in PPLO broth (Difco Laboratories, Detroit, Mich.) supplemented with rabbit serum (10% [vol/vol]) and harvested by centrifugation were shown to contain rabbit immunoglobulin G (IgG) (approximately 4 to 10% of total cell proteins) and to produce IgM autoantibodies to IgG when inoculated into rabbits.
mesh_terms: D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000096:biosynthesis*; D001323:Autoantibodies / Q000096:biosynthesis*; D007074:Immunoglobulin G / Q000276:immunology*; D007075:Immunoglobulin M / Q000096:biosynthesis*; D009174:Mycoplasma / Q000276:immunology*; D010510:Periodontal Diseases / Q000276:immunology* / Q000382:microbiology; D011817:Rabbits
chemical_list: D000888:Antibodies, Anti-Idiotypic; D001323:Autoantibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M