[Antibodies reacting with the antigens of the human immunodeficiency virus in systemic lupus erythematosus].
A study was made of the level of anti-HTLV-111 using an enzyme immunoassay (Emzygnost-anti-HTLV-111) in 75 donors and 143 patients with various diseases including SLE (57), rheumatoid arthritis (9), Sjögren's disease (3), Bekhterev's disease (2), polymyositis (2), dilatation cardiomyopathy (30), and acute lymphocytic leukemia (40). Anti-HTLV-111 were detected in 26 SLE patients and in one patient with polymyositis. A study of positive sera using immunoblotting showed no interaction with virus antigens. A conclusion was made that the detection of anti-HTLV-111 in systemic rheumatoid diseases was a false-positive result.
D000914:Antibodies, Viral / Q000032:analysis* / Q000276:immunology; D000937:Antigen-Antibody Reactions; D000956:Antigens, Viral / Q000276:immunology*; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D006678:HIV / Q000276:immunology*; D006801:Humans; D007118:Immunoassay; D007945:Leukemia, Lymphoid / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D012216:Rheumatic Diseases / Q000276:immunology
D000914:Antibodies, Viral; D000956:Antigens, Viral
Antitela, reagiruiushchie s antigenami virusa immunodefitsita cheloveka pri sistemnoĭ krasnoĭ volchanke.