Transforming growth factors and histopathologic interpretation.
Transforming growth factors, a group of small proteins that, under proper circumstances, induce the reversible morphologic transformation of mature cells, are produced by tumor cells and by stimulated differentiated cells. The pseudomalignant conditions that we recognize histologically may, in many instances, be explained by the action of these molecules.
D002454:Cell Differentiation / Q000187:drug effects*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D006801:Humans; D006965:Hyperplasia / Q000209:etiology / Q000473:pathology; D009363:Neoplasm Proteins / Q000494:pharmacology; D009369:Neoplasms / Q000209:etiology / Q000473:pathology*; D010455:Peptides / Q000494:pharmacology*; D015291:Transforming Growth Factors
D009363:Neoplasm Proteins; D010455:Peptides; D015291:Transforming Growth Factors