Ischaemic colitis in a patient treated with glypressin for bleeding oesophageal varices.
This paper reports a case of ischaemic colitis observed in a male patient with acute oesophageal variceal bleeding treated with Glypressin (triglycyl lysine vasopressin). The therapeutic effect of this substance depends on the lowering of the portal vein pressure brought about by a vasoconstriction of the vessels of the splanchnic region. The undesired complication of ischaemic colitis occurred as a result of a reduction in blood flow to the colonic mucosa.
D000328:Adult; D003092:Colitis / Q000139:chemically induced*; D003106:Colon / Q000098:blood supply*; D004932:Esophageal and Gastric Varices / Q000188:drug therapy*; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy*; D006801:Humans; D007511:Ischemia / Q000139:chemically induced*; D008236:Lypressin / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D012039:Regional Blood Flow / Q000187:drug effects; D000077585:Terlipressin
D008236:Lypressin; D000077585:Terlipressin