Genetic variants of complement component 3 (C3) in DR4 positive and DR4 negative rheumatoid arthritis.
C3 allotypes were defined in 86 Caucasoid patients with rheumatoid arthritis living in the north west of England and in 80 local, healthy controls. C3 allotype and phenotype frequencies were similar in RA (whether DR4 positive or negative) and control groups.
D001172:Arthritis, Rheumatoid / Q000235:genetics* / Q000276:immunology; D003176:Complement C3 / Q000235:genetics*; D015804:HLA-DR4 Antigen; D000949:Histocompatibility Antigens Class II / Q000032:analysis*; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000235:genetics; D010641:Phenotype; D011110:Polymorphism, Genetic
D003176:Complement C3; D015804:HLA-DR4 Antigen; D000949:Histocompatibility Antigens Class II; D007126:Immunoglobulin Allotypes