Persistent generalized lymphadenopathy in Northeastern Italy: increased frequency of HLA-DR 5.
We undertake a study of Italian intravenous drug abusers and male homosexuals with the prolonged generalized lymphadenopathy syndrome (PGL). 75% of the subjects had the HLA-DR 5 antigen (relative risk 3.25). Only one patient was DR 2 positive. 14/20 subjects had anti-HTLV III antibodies and immunological malities were a rather constant finding.
D000163:Acquired Immunodeficiency Syndrome / Q000209:etiology; D000293:Adolescent; D000328:Adult; D005260:Female; D015805:HLA-DR5 Antigen; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006716:Homosexuality; D006801:Humans; D007558:Italy; D008206:Lymphatic Diseases / Q000235:genetics / Q000276:immunology*; D008297:Male; D019966:Substance-Related Disorders
D015805:HLA-DR5 Antigen; D000949:Histocompatibility Antigens Class II