Reciprocal translocations and full trisomy (trisomy 18 and trisomy 21) in the offspring.
In this report, we present examples of trisomy 18 and trisomy 21, both resulting from maternal reciprocal translocations: 46, XX, t(5;18) (q21;q11) and 46, XX, t(5;21) (p11.2;p11), respectively.
D000015:Abnormalities, Multiple / Q000196:embryology / Q000235:genetics; D002887:Chromosomes, Human, Pair 18; D002891:Chromosomes, Human, Pair 21; D005260:Female; D006801:Humans; D011247:Pregnancy; D014178:Translocation, Genetic; D014314:Trisomy