MPTP toxicity: clinical features.
MPTP causes acute irreversible Parkinsonism in man that mimics the idiopathic condition exactly. It is therefore a better model of the naturally occurring disease than previously described cases secondary to other chemicals or viruses.
D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; D001971:Bromocriptine / Q000627:therapeutic use; D002140:California; D002617:Chemical Industry; D004219:District of Columbia; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000188:drug therapy; D011725:Pyridines / Q000506:poisoning*
D011725:Pyridines; D001971:Bromocriptine; D007980:Levodopa; D015632:1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine