[Features of the distribution of HLA-antigens among patients with endogenous psychoses].
Distribution of HLA antigens of A and B loci was studied in 200 schizophrenics, 77 patients with manic-depressive psychosis of different forms, and in 350 healthy individuals. The findings included a significant elevation in the levels of the B7 antigen in both groups of patients, of antigen B12 in individuals with paroxysmal schizophrenia as well as a decrease in the concentrations of antigen B35 in recurrent schizophrenia. Patients with monopolar manic-depressive psychosis showed increased content of antigen B14 and decreased levels of antigen B5. The data obtained confirm heterogeneity of endogenic psychoses with regard to this sign.
D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000235:genetics* / Q000276:immunology; D003866:Depressive Disorder / Q000235:genetics* / Q000276:immunology; D005819:Genetic Markers; D005838:Genotype; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008875:Middle Aged; D010641:Phenotype; D012559:Schizophrenia / Q000235:genetics* / Q000276:immunology
D005819:Genetic Markers; D006680:HLA Antigens
Osobennosti raspredeleniia HLA-antigenov u bol'nykh éndogennymi psikhozami.