The effect of heat-stable extract from bovine sublingual salivary glands on the carbohydrate metabolism of the rabbit.
This extract (SLF3) caused hyperglycaemia when injected intraperitoneally (i.p.) into rabbits (20 mg/kg body wt) which was maximal at 0.5 h and took 2 h to return to the initial value. SLF3 also produced a two-fold increase in corticosteroid levels compared to controls, so the increase in blood glucose was probably mediated by adrenal cortical hormone stimulation.
D015062:11-Hydroxycorticosteroids / Q000097:blood; D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D002417:Cattle; D008297:Male; D011817:Rabbits; D013361:Sublingual Gland / Q000378:metabolism*; D014020:Tissue Extracts / Q000494:pharmacology*
D015062:11-Hydroxycorticosteroids; D001786:Blood Glucose; D014020:Tissue Extracts