title: Synthesis and properties of some derivatives of 2H-4,6-dimethylpyrido[3,2-d]isothiazolin-3-one-1,1-dioxide.
abstract: The synthesis of 2H-4,6-dimethylpyrido[3,2-d]isothiazolin-3-one-1,1-dioxide and its 2-N-substituted derivatives are described. Structures of the obtained compounds were determined on the basis of elemental analyses and spectral data I.R., N.M.R., MS. Preliminary information on the pharmacological properties of the obtained compounds also given.
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001794:Blood Pressure / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D007928:Lethal Dose 50; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D051381:Rats; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D011725:Pyridines; D013844:Thiazoles