Host serum protein levels in cysts of human hydatidosis.
8 proteins (albumin, IgG, IgM, IgA, C3c, C4, orosomucoid and alpha 1 antitrypsin) were determined by laser immunonephelometry in hydatid cyst fluid from cysts and sera from 16 patients. The cystic level of albumin was 34.5 +/- SD 59.1 micrograms/ml (range 3.6-85); of IgG 12.9 +/- 18.7 micrograms/ml (1.9-75); of IgM 10.5 +/- 10.4 micrograms/ml (3-37); and of IgA 7.2 +/- 3.5 micrograms/ml (4-19.7). The 4 other proteins represented a smaller fraction: C3c, 0.9 +/- 0.6 micrograms/ml (0.5-2.5); C4, 1.3 +/- 0.9 micrograms/ml (0.5-3.5); orosomucoid, 2.8 +/- 2.3 micrograms/ml (1.4-9.2); and alpha 1-antitrypsin, 5 +/- 4.5 micrograms/ml (2-19). These 8 host proteins constituted 24.6 +/- 24.5% (2.4-76) of the total hydatid cyst fluid proteins (343.7 +/- 172.1 micrograms/ml, range 180-900). The albumin/IgG ration of 3 +/- 2.8 (0.4-10.8) in hydatid cyst fluid was more variable than that in sera, 2 +/- 0.5 (1.2-2.7).
D001798:Blood Proteins / Q000378:metabolism*; D003176:Complement C3 / Q000378:metabolism; D015932:Complement C3c; D003181:Complement C4 / Q000378:metabolism; D004443:Echinococcosis / Q000097:blood*; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007074:Immunoglobulin G / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D009961:Orosomucoid / Q000378:metabolism; D012709:Serum Albumin / Q000378:metabolism; D000515:alpha 1-Antitrypsin / Q000378:metabolism
D001798:Blood Proteins; D003176:Complement C3; D003181:Complement C4; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D009961:Orosomucoid; D012709:Serum Albumin; D000515:alpha 1-Antitrypsin; D015932:Complement C3c