The importance of NPSH on the radiosensitizing effect of oxygen in Chinese hamster V-79 cells.
The radiosensitivity of Chinese hamster V-79-171B fibroblasts increased more rapidly with increasing partial pressure of oxygen when the cell cultures had low endogenous levels of non-protein sulphydryl (NPSH), about 5 mumol per cell compared with about 15 mumol per cell. There was a good correlation between initial NPSH content and sensitization by oxygen concentrations between 0.06 and 0.7 per cent.
D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects*; D006224:Cricetinae; D066298:In Vitro Techniques; D010100:Oxygen / Q000502:physiology*; D011836:Radiation Tolerance; D013438:Sulfhydryl Compounds / Q000502:physiology*
D013438:Sulfhydryl Compounds; D010100:Oxygen