Relationship of plasma level of vitamin C to mortality from ischemic heart disease.
The present epidemiological data support and extend previous evidence in men and animals. Thus, a poor plasma status of vitamin C (less than 23 microM = 0.4 mg/dl) and/or of cholesterol-standardized vitamin E (less than 20-21.5 microM = 9 mg/l) occurs in westernized countries with an increased risk of IHD. A poor status in the major essential antioxidants may be a hitherto underrated, at least permissive, risk factor of IHD that could, at least in some European countries, substantially complement the previously established risk factors such as hypercholesterolemia.
D000328:Adult; D001205:Ascorbic Acid / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000453:epidemiology / Q000401:mortality*; D003430:Cross-Sectional Studies; D005387:Finland; D006801:Humans; D007494:Ireland; D007558:Italy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012306:Risk; D012606:Scotland; D013557:Switzerland; D014810:Vitamin E / Q000097:blood
D014810:Vitamin E; D002784:Cholesterol; D001205:Ascorbic Acid