[Simple method of risk calculation in X-linked diseases].
The estimation of genetic risks in X-linked recessive disorders is a special case of Bayesian approach to probability calculation. Computing directly an estimation of the inverse of the risk is easier in this particular situation of only two mutually exclusive hypothesis: this function can be written in the form T = 1 + (To -1) X R, where R is a product of likehood ratios. The ratio of two probability density function represent a single factor, which is more manipulatable than the two components of the classical method.
D005260:Female; D005808:Genes, Recessive; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D009136:Muscular Dystrophies / Q000235:genetics*; D010375:Pedigree; D011336:Probability; D012306:Risk; D014960:X Chromosome
Une méthode simple de calcul du risque dans les maladies liées à l'X.