title: [Malignant xanthogranuloma of the cervicofacial region. Optical and ultrastructural morphology. Apropos of 4 cases].
abstract: The 4 cases of malignant xanthogranuloma reported here are peculiar because of their unusual localization in the cervico-facial area and of their good outcome (3 patients are alive without recurrence more than 6 years after chemotherapy and radiotherapy). Besides the histological study, the 4 cases were examined by immunohistochemical methods : vimentin was positive in 20 to 40% of cells and lysozyme in 5 to 15% of cells. In addition, one case was studied by electron microscope which showed the polymorphism of tumoral cells.
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005153:Facial Neoplasms / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure; D005260:Female; D006099:Granuloma / Q000473:pathology* / Q000628:therapy; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D011379:Prognosis; D014973:Xanthomatosis / Q000473:pathology* / Q000628:therapy
vernacular_title: Xanthogranulome malin de la région cervico-faciale. Morphologie optique et ultrastructurale. A propos de 4 observations.