title: [The immune system of the lungs in healthy subjects and in chronic nonspecific diseases].
abstract: Resistance of lung to the action of damaging factors is determined by the mechanisms of non-specific defence and immunologic responseveness that is expressed by systemic and local immune reactions. Local immune response in bronchi is brought about by a lymphoid tissue associated with bronchi. Alveolar macrophages carry out a main protective function in the respiratory parts. Participation of an immune system in the pathogenesis of chronic non-specific diseases is expressed by a lymphoid tissue hyperplasia, increased synthesis of immunoglobulins, increased number of macrophages and neutrophils. The role of an immunocomplex mechanism and cell hypersensitivity factors in the focus of damage remains unclear. A promising hypothesis in the study of immunopathology of chronic non-specific lung diseases is that of the role of an immune imbalance is their etiology and pathogenesis.
mesh_terms: D001980:Bronchi / Q000276:immunology; D001987:Bronchiectasis / Q000276:immunology; D001991:Bronchitis / Q000276:immunology; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000276:immunology; D007136:Immunoglobulins / Q000032:analysis; D008168:Lung / Q000276:immunology*; D008173:Lung Diseases, Obstructive / Q000276:immunology*; D008198:Lymph Nodes / Q000276:immunology; D008221:Lymphoid Tissue / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D010587:Phagocytosis; D011650:Pulmonary Alveoli / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D007071:Immunoglobulin A, Secretory; D007136:Immunoglobulins
vernacular_title: Immunnaia sistema legkikh v norme i pri khronicheskikh nespetsificheskikh zabolevaniiakh.