Preformulation salt selection. Physical property comparisons of the tris(hydroxymethyl)aminomethane (THAM) salts of four analgesic/antiinflammatory agents with the sodium salts and the free acids.
D000700:Analgesics / Q000032:analysis*; D000893:Anti-Inflammatory Agents / Q000032:analysis*; D001682:Biological Availability; D055598:Chemical Phenomena; D002621:Chemistry; D006863:Hydrogen-Ion Concentration; D012492:Salts / Q000032:analysis; D012964:Sodium / Q000032:analysis; D012995:Solubility; D012996:Solutions; D014325:Tromethamine / Q000032:analysis*
D000700:Analgesics; D000893:Anti-Inflammatory Agents; D012492:Salts; D012996:Solutions; D014325:Tromethamine; D012964:Sodium