The localization of a Mason-Pfizer monkey virus-related antigen in jaagsiekte tumour tissue and cell lines.
Mason-Pfizer monkey virus-related antigen was detected in 3 out of 5 jaagsiekte lungs examined using a direct immunoperoxidase staining technique with anti-MPMV p27 serum. Most of the antigen was localized in the alveolar lumina of the lesions. The reaction was further characterised on immune blots and found to involve a protein with a molecular mass of 29 000 daltons (JSRV p29). JSRV p29 antigen was also detected in 2 jaagsiekte cell lines.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D002460:Cell Line; D006651:Histocytochemistry; D007118:Immunoassay; D007124:Immunoenzyme Techniques; D008168:Lung / Q000276:immunology / Q000382:microbiology; D011648:Pulmonary Adenomatosis, Ovine / Q000276:immunology / Q000382:microbiology*; D012190:Retroviridae / Q000276:immunology*; D012756:Sheep
D000956:Antigens, Viral