[Successful pregnancy after kidney transplantation and cyclosporin A].
A 21-year-old patient is described who, with a kidney transplant and immunosuppressive treatment with Cyclosporin A, successfully concluded pregnancy. Effective immunosuppression is especially important during pregnancy with its increased risk of transplant rejection. Aside from conventional substances such as azathioprine and steroids, Cyclosporin A (Sandimmun) seems to be the most effective substance available in transplantation medicine today. There is, however, still insufficient knowledge of the effects of Cyclosporin A during pregnancy, so that an endangered pregnancy must be expected during this type of therapy. Because of persistent premature labor in spite of tocolytic treatment, a cesarean section was performed in the 36th week of pregnancy after establishing pulmonary maturity. A review of the literature points out the presently known problems connected with Cyclosporin A intake during pregnancy.
D000328:Adult; D003524:Cyclosporins / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D016030:Kidney Transplantation; D007752:Obstetric Labor, Premature / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D012306:Risk
D003524:Cyclosporins
Erfolgreiche Schwangerschaft bei Nierentransplantation und Cyclosporin A.