title: [Criteria of the evaluation of the cause-effect relationship of toxic substances in the industrial environment].
abstract: The author at first analyses the concepts of exposure, biological monitoring and dose. Therefore, he takes into consideration the varieties of the occupational hazard underlining the more and more prominent role of the different co-factors causing occupational diseases. Then he examines the judgement of the legal criteria in theme of occupational diseases, coming to the conclusion that, for the diagnosis of chronic intoxications, it is difficult to recognise cause-effect relationship in industrial toxicology due to: poor knowledge of toxic action mechanism, incomplete information on metabolic-dysfunctions and last, the frequent interference of non occupational factors which are not always easy to identify.
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects* / Q000032:analysis; D004305:Dose-Response Relationship, Drug; D004784:Environmental Monitoring; D006801:Humans; D009784:Occupational Diseases / Q000139:chemically induced* / Q000517:prevention & control; D012307:Risk Factors
chemical_list: D000395:Air Pollutants, Occupational
vernacular_title: Criteri di valutazione del rapporto causa--effetto di tossici in ambiente industriale.