Corticosteroid receptor in type II pneumocytes of the rat.
Glucocorticoid receptor in rat type II pneumocytes has been characterized. The Scatchard plot analysis of 3H-dexamethasone binding to type II cells showed a single class of binding sites. The apparent Kd of 3H-dexamethasone binding by a whole cell assay was 9.1 nM and the maximal binding capacity was 78.0 f mol/10(6) cells (0.31 pmol/mg cytosol protein).
D000818:Animals; D003907:Dexamethasone / Q000378:metabolism; D007700:Kinetics; D008168:Lung / Q000166:cytology*; D008858:Microscopy, Phase-Contrast; D051381:Rats; D011965:Receptors, Glucocorticoid / Q000032:analysis*
D011965:Receptors, Glucocorticoid; D003907:Dexamethasone