[Ultrastructure of immunocytes in the lymph of the thoracic duct during rejection of the allogenically transplanted heart in the dog].
Substructural changes in the immunocytes of thoracic duct lymphatic fluid were studied in allogeneous heart transplant experiments on 47 dogs in an effort to identify factors associated with or inductive of the process of rejection. The initial changes could be shown to be related to the inevitable trauma associated with the transplant procedure. At the same time evidence of increased physiologic activity of the cells begins to appear and lymphoplasmocytes begin to enter the process along with the onset of antibody production. Immediately before rejection occurs, the number of lymphoplasmocytes increases which however often show degenerative changes on ultrastructural examination.
D000818:Animals; D000917:Antibody Formation; D002467:Cell Nucleus / Q000648:ultrastructure; D004285:Dogs; D006084:Graft Rejection; D016027:Heart Transplantation; D007958:Leukocyte Count; D008196:Lymph / Q000166:cytology*; D008854:Microscopy, Electron; D010950:Plasma Cells / Q000276:immunology / Q000648:ultrastructure*
Die Ultrastruktur von Immunozyten aus der Lymphe des Ductus thoracicus im Prozess der Rejektion von allogen transplantierten Herzen bei Hunden.