title: Distribution of PNMT-immunoreactive neurons in the cat medulla oblongata.
abstract: The distribution and morphology of presumptive adrenaline neurons in the cat medulla oblongata were studied in conjunction with the indirect immunoperoxidase technique utilizing antibody raised against bovine adrenal phenylethanolamine-N-methyltransferase (PNMT), an enzyme which converts noradrenaline to adrenaline. Small PNMT-immunoreactive (IR) perikarya are located in the dorsomedial part of the medulla (C2 group) extending from P17 to P12, and larger ones in the ventrolateral part (C1 group) from P11 to P9 of the caudorostral extent. In the rostral medulla (P11-10), larger cells extended more dorsally in the lateral tegmental field, where only a few catecholamine cells are localized. No midline PNMT-IR cells were identified corresponding to C3 cell group in the rat. Distinct longitudinal PNMT-IR axon bundles can be traced through the dorsal part of the lateral tegmental field. Comments are made on the relative localizations of the PNMT-IR and DBH-IR cells, as well as on species differences in comparison with the results reported in the rat.
mesh_terms: D000311:Adrenal Glands / Q000201:enzymology; D000818:Animals; D002415:Cats; D002417:Cattle; D005260:Female; D007124:Immunoenzyme Techniques; D008297:Male; D008526:Medulla Oblongata / Q000033:anatomy & histology / Q000166:cytology / Q000201:enzymology*; D009474:Neurons / Q000166:cytology / Q000201:enzymology*; D010625:Phenylethanolamine N-Methyltransferase / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: D010625:Phenylethanolamine N-Methyltransferase