[Metabolism of sex hormones and adipose tissue].
Adipose tissue is a catchment area for storing, converting and releasing the sex hormones. The role of adipose tissue in the general metabolism of endogenous and exogenous steroids deserves to be considered seeing how big the volume of fat is in the human body. The fatty pool of sex steroids seems to be greater than the plasma pool. Hormones which have been stored can be released by adipocytes into the general circulation even if they have been converted while in the adipocytes. Similarly, androgens are changed by adipose tissue into oestrogens by aromatisation and are liberated. This extraglandular production of oestrogens can have clinical and pathological consequences.
D000273:Adipose Tissue / Q000032:analysis / Q000378:metabolism*; D000293:Adolescent; D000328:Adult; D000728:Androgens / Q000378:metabolism; D000735:Androstenedione / Q000378:metabolism; D001141:Aromatase / Q000378:metabolism; D002648:Child; D005260:Female; D012739:Gonadal Steroid Hormones / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D008297:Male; D008593:Menopause; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism; D010053:Ovary / Q000378:metabolism; D011627:Puberty; D011944:Receptors, Androgen / Q000032:analysis; D011959:Receptors, Estradiol / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis
D000728:Androgens; D012739:Gonadal Steroid Hormones; D011944:Receptors, Androgen; D011959:Receptors, Estradiol; D011980:Receptors, Progesterone; D000735:Androstenedione; D001141:Aromatase
Métabolisme des hormones sexuelles et tissu adipeux.