Evaluation of non-specific bronchial hyperreactivity in different respiratory diseases.
Bronchial hyperreactivity (BHR) has been observed in respiratory disorders other than asthma but asthmatics usually show BHR to differing degrees. The presence and degree of BHR in asthma was evaluated and compared with that in other respiratory disorders. High BHR was observed in asthma (84%, with no difference between atopics and non-atopics), recurrent or persistent cough (36%), laryngeal spasm (50%), Kartagener's syndrome (66%) and cystic fibrosis. BHR was low in patients with allergic rhinitis but no asthma and was absent in patients with unexplained dyspnoea (100%) and in healthy controls (91%).
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000150:complications; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000503:physiopathology; D005541:Forced Expiratory Volume; D006801:Humans; D007619:Kartagener Syndrome / Q000503:physiopathology; D016210:Methacholine Chloride; D008688:Methacholine Compounds; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D012130:Respiratory Hypersensitivity / Q000150:complications*; D012140:Respiratory Tract Diseases / Q000150:complications*
D008688:Methacholine Compounds; D016210:Methacholine Chloride