title: [Development of methods for research on the clinical pharmacology of drugs used in cardiovascular diseases].
abstract: Repeated pharmacodynamic studies of more than 30 drugs with hypotensive, antianginal and antiarrhythmic effects were performed in over 1,200 patients suffering from cardiovascular diseases, predominantly ischemic heart disease and hypertensive disease. The result of the work was optimization of the drug dosage regimen during course treatment; real diagnostic possibilities of functional research methods were revealed.
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D002317:Cardiovascular Agents / Q000494:pharmacology*; D002986:Clinical Trials as Topic / Q000379:methods; D003327:Coronary Disease / Q000188:drug therapy; D006334:Heart Function Tests / Q000379:methods; D006801:Humans; D006973:Hypertension / Q000188:drug therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D002317:Cardiovascular Agents
vernacular_title: Razrabotka metodov issledovaniia klinicheskoĭ farmakologii lekarstvennykh sredstv, primeniaemykh pri serdechno-sosudistykh zabolevaniiakh.