Augmentin (amoxycillin-clavulanic acid) compared with amoxycillin alone in the treatment of urinary tract infections in the elderly.
Sixty-seven patients (mean age 82 years) with urinary tract infection were treated with either Augmentin or amoxycillin in a double-blind randomised trial. Of the 52 patients who completed 5 days treatment, 21/24 (87.5%) responded to Augmentin but only 12/28 (43%) responded to amoxycillin. Five of eight patients who had failed to respond to amoxycillin responded to Augmentin.
D000368:Aged; D000658:Amoxicillin / Q000008:administration & dosage / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D011897:Random Allocation; D014552:Urinary Tract Infections / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D004338:Drug Combinations; D019818:Clavulanic Acid; D000658:Amoxicillin