title: Production of monodispersed capsules.
abstract: A new prehardening process has been demonstrated by passing falling drops through a fine mist of hardening solution, in which drops were generated as monodispersed and concentric two-phase particles. A mixture of vegetable oil and vitamin E has been encapsulated using calcium alginate for rapid hardening and hydroxy propyl methyl cellulose acetate succinate for slow hardening. Both hardening agents produced satisfactory stable encapsulation.
mesh_terms: D000464:Alginates; D002214:Capsules; D004339:Drug Compounding / Q000295:instrumentation / Q000379:methods*; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D008747:Methylcellulose / Q000031:analogs & derivatives*
chemical_list: D000464:Alginates; D002214:Capsules; D006603:Hexuronic Acids; C048331:hydroxypropylmethylcellulose acetate succinate; D020723:Glucuronic Acid; D008747:Methylcellulose