[Hematopoietic effectiveness of prostaglandin synthesis inhibitors during fractionated irradiation].
In experiments on mice, a pronounced haemostimulating effect of prostaglandin biosynthesis inhibitors was registered in conditions of fractionated irradiation. The use of the preparations like these may be promising in solving the problem of protection of the haemopoietic tissue exposed during the radiotherapy course.
D000818:Animals; D004008:Diclofenac / Q000494:pharmacology; D004307:Dose-Response Relationship, Radiation; D006410:Hematopoiesis / Q000187:drug effects / Q000528:radiation effects*; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D051379:Mice; D011448:Prostaglandin Antagonists / Q000494:pharmacology*; D011833:Radiation Injuries, Experimental / Q000097:blood* / Q000517:prevention & control; D011879:Radiotherapy Dosage; D013997:Time Factors; D014916:Whole-Body Irradiation
D011448:Prostaglandin Antagonists; D004008:Diclofenac; D007213:Indomethacin
Gemostimuliruiushchaia éffektivnost' ingibitorov biosinteza prostaglandinov v usloviiakh fraktsionirovannogo oblucheniia.