title: The simultaneous presence of Langerhans' cell and interdigitating cell antigenic markers on inflammatory dendritic cells.
abstract: Immunohistological studies have been performed on tissues from various dermatological conditions using two monoclonal antibodies, RFD1 and NA1/34. These reagents were used to determine whether antigen expression restricted to interdigitating cells (RFD1+) and Langerhans' cells (NA1/34+) in normal tissues might occur together on dendritic cells involved in cutaneous inflammatory reactions. The results presented demonstrate that in psoriasis, allergic contact dermatitis and atopic dermatitis a proportion of the inflammatory dendritic cells express both antigens.
mesh_terms: D000954:Antigens, Surface / Q000032:analysis*; D002465:Cell Movement; D003876:Dermatitis, Atopic / Q000276:immunology*; D003877:Dermatitis, Contact / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007801:Langerhans Cells / Q000276:immunology*; D008221:Lymphoid Tissue / Q000166:cytology; D011565:Psoriasis / Q000276:immunology*; D012867:Skin / Q000276:immunology*
chemical_list: D000954:Antigens, Surface