Malaria transmitted to humans by mosquitoes infected from cultured Plasmodium falciparum.
Malaria was transmitted to six normal human volunteers by mosquitoes infected from cultured gametocytes of Plasmodium falciparum. This method, which offers advantages over other methods of infecting volunteers, will be useful for evaluating the efficacy of human malaria vaccines.
D000328:Adult; D000852:Anopheles / Q000469:parasitology; D002478:Cells, Cultured; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D008288:Malaria / Q000635:transmission*; D008297:Male; D010963:Plasmodium falciparum / Q000254:growth & development