title: Imipenem-cilastatin: the first thienamycin antibiotic.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D015377:Cilastatin; D000077728:Cilastatin, Imipenem Drug Combination; D003521:Cyclopropanes / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use; D004338:Drug Combinations / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use; D006801:Humans; D015378:Imipenem; D007223:Infant; D007231:Infant, Newborn; D007700:Kinetics; D008826:Microbial Sensitivity Tests; D013845:Thienamycins / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D003521:Cyclopropanes; D004338:Drug Combinations; D013845:Thienamycins; D015377:Cilastatin; D015378:Imipenem; D000077728:Cilastatin, Imipenem Drug Combination