Age-dependent resistance to the toxic effects of paraquat in relation to superoxide dismutase activity in rat lung.
Young rats are much more resistant to the toxic effects of orally-administered paraquat than are older rats. The possible relation of this phenomenon to the activity of superoxide dismutase in lung is discussed.
D000375:Aging; D000818:Animals; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology*; D010269:Paraquat / Q000633:toxicity*; D051381:Rats; D013482:Superoxide Dismutase / Q000378:metabolism*
D013482:Superoxide Dismutase; D010269:Paraquat