The biological properties of reduced nitroheterocyclics and possible underlying biochemical mechanisms.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D005609:Free Radicals; D005978:Glutathione / Q000378:metabolism; D006801:Humans; D006898:Hydroxylamines / Q000378:metabolism; D000860:Hypoxia; D009581:Nitrofurans / Q000378:metabolism / Q000494:pharmacology*; D009593:Nitroimidazoles / Q000378:metabolism / Q000494:pharmacology*; D009696:Nucleic Acids / Q000378:metabolism; D010084:Oxidation-Reduction; D011506:Proteins / Q000378:metabolism; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology*; D013438:Sulfhydryl Compounds / Q000378:metabolism
D005609:Free Radicals; D006898:Hydroxylamines; D009581:Nitrofurans; D009593:Nitroimidazoles; D009696:Nucleic Acids; D011506:Proteins; D011838:Radiation-Sensitizing Agents; D013438:Sulfhydryl Compounds; D005978:Glutathione