Homologous regions within M protein genes in group A streptococci of different serotypes.
DNA hybridization with probes from the structural gene for the M6 protein shows that the carboxy-terminal region (proximal to the cell surface) is conserved among strains of different M serotypes. The amino-terminal region, which is more available to immunological surveillance, exhibits greater variation.
D000942:Antigens, Bacterial / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics; D005796:Genes; D005798:Genes, Bacterial; D013297:Streptococcus pyogenes / Q000235:genetics*
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D004269:DNA, Bacterial