title: [Comparison of 12-month treatment with porcine and human insulin (semisynthetic and biosynthetic)].
abstract: In recent years two forms of human insulin--semisynthetic and biosynthetic--have been perfected and several experiments have been conducted to assess their effective therapeutic advantages. The present study compares the activity of porcine and human insulin. On the basis of the parameters considered--fasting and post-prandial glycaemia, body weight, glycosilated Hb--it is concluded that are no substantial therapeutic advantages in either porcine or human insulin. For this reason the latter should be reserved for special cases like initial juvenile etc., but offers no advantage in patients already responding adequately to the old insulin preparations.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000008:administration & dosage* / Q000096:biosynthesis / Q000138:chemical synthesis; D008297:Male; D008875:Middle Aged; D013552:Swine; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin
vernacular_title: Confronto a 12 mesi di trattamento tra insulina porcina ed insulina umana (semisintetica e biosintetica).