Neurofibrillary tangles from Alzheimer's disease brain purified using a cell sorter.
We have used a monoclonal antibody to label and purify neurofibrillary tangles using a cell sorter. The method should prove invaluable in future analyses of the biochemical makeup of neurofibrillary tangles, which in turn will greatly assist our comprehension of tangle pathology.
D000544:Alzheimer Disease / Q000473:pathology*; D000911:Antibodies, Monoclonal; D002469:Cell Separation / Q000295:instrumentation / Q000379:methods*; D005455:Fluorescent Antibody Technique; D006801:Humans; D009454:Neurofibrils / Q000473:pathology*
D000911:Antibodies, Monoclonal