Treatment of mental disorders in pregnancy. A review of psychotropic drug risks and benefits.
Pregnancy can be complicated by affective or psychotic illnesses severe enough to threaten the health and life of both mother and fetus. In many cases, nonbiological interventions like psychotherapy or hospitalization in a supportive milieu will be insufficient, and use of a psychotropic drug will be indicated. This paper outlines the characteristics of maternal and fetal physiology that influence drug risks and then reviews the specific risks and benefits associated with antipsychotics, antidepressants, and lithium.
D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008094:Lithium / Q000009:adverse effects / Q000627:therapeutic use; D001523:Mental Disorders / Q000188:drug therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*; D012306:Risk
D000928:Antidepressive Agents; D011619:Psychotropic Drugs; D008094:Lithium