Ultrastructural localization of enkephalin immunoreactivity in the substantia nigra of the monkey.
Localization of enkephalin-like immunoreactivity in the substantia nigra of the Japanese red-faced monkey was investigated by light and electron microscopy using the peroxidase-anti-peroxidase method. Immunoreactive precipitates were predominantly distributed in the nerve fibers of the substantia nigra pars reticulata but not in the perikarya, and a low density of immunoreactive enkephalin was found in the pars compacta of this nucleus. Electron microscopic observations showed that enkephalin-immunoreactive precipitates were located in axon terminals containing numerous small clear vesicles either with or without labeled large granular vesicles and formed predominantly axo-dendritic synapses.
D000818:Animals; D001369:Axons / Q000276:immunology; D004744:Enkephalin, Methionine / Q000276:immunology*; D005260:Female; D006651:Histocytochemistry; D007120:Immunochemistry; D007124:Immunoenzyme Techniques; D008251:Macaca; D008854:Microscopy, Electron; D013378:Substantia Nigra / Q000276:immunology* / Q000648:ultrastructure; D013569:Synapses / Q000276:immunology
D004744:Enkephalin, Methionine