[Benign chronic bullous dermatosis in childhood with involvement of the mouth mucosa].
We report on a rare case of benign chronic bullous dermatosis of childhood (BCBDC) in a 5-year-old girl. In addition to the characteristic symptoms such as abrupt onset of the disease, tense blisters, predominant affection of the face, and later imitation of impetigo, we observed uncommonly extensive involvement of the oral mucosa. Whereas histopathology was not diagnostic, direct immunofluorescence could verify BCBDC as it showed linear deposits of IgA along the basement membrane zone. This case gives rise to the discussion of the clinical entity and nomenclature of BCBDC in relation to similar bullous diseases of childhood and adults.
D001485:Basement Membrane / Q000473:pathology; D002675:Child, Preschool; D002908:Chronic Disease; D003176:Complement C3 / Q000378:metabolism; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D009061:Mouth Mucosa / Q000473:pathology; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*; D013280:Stomatitis / Q000473:pathology*
D003176:Complement C3; D007070:Immunoglobulin A
Benigne chronisch bullöse Dermatose der Kindheit mit Mundschleimhaut-Beteiligung.