Correlation of hexokinase content and basal energy metabolism in discrete regions of rat brain.
Brain hexokinase (ATP:D-hexose 6-phosphotransferase, EC 2.7.1.1) levels in seven regions of rat brain were estimated by photometric measurement of immunofluorescence in cryostat-cut sections. When compared with basal rates of glucose metabolism in these regions, estimated by the 6-[14C]glucose method, a significant correlation was observed. Thus, hexokinase content reflects metabolic energy demands.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D004734:Energy Metabolism; D005455:Fluorescent Antibody Technique; D005947:Glucose / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism*; D006651:Histocytochemistry; D007700:Kinetics; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D006593:Hexokinase; D005947:Glucose