Scleroderma in childhood.
Scleroderma is a rare disease in children. Heterogeneous in its many forms, it ranges from circumscribed and self-limited pigmentary disorders to disabling and disfiguring involvement of an extremity. It also may include diffuse skin disease, multiple internal organ derangements, and a rapidly fatal outcome. Outcome varies widely and is related to the location and extent of cutaneous involvement, evaluation of disfigurement or impairment, and which treatment resources are available.
D002648:Child; D004802:Eosinophilia; D005208:Fasciitis; D006801:Humans; D011928:Raynaud Disease; D012594:Scleroderma, Localized / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D012595:Scleroderma, Systemic / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D013577:Syndrome