A comparison of the incidence of peptic ulceration for fenbufen, indomethacin and aspirin treated patients compared with the general population.
Survival analysis techniques were used to compare the long-term incidence of peptic ulceration occurring in fenbufen, indomethacin and aspirin treated patients with a "background" incidence for the whole population. The results of this analysis indicate that the incidence of peptic ulceration occurring in patients receiving long-term therapy with fenbufen is comparable to the background incidence for the whole population.
D000206:Actuarial Analysis; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects*; D002986:Clinical Trials as Topic; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects*; D007256:Information Systems; D010437:Peptic Ulcer / Q000139:chemically induced* / Q000453:epidemiology; D010654:Phenylbutyrates; D011422:Propionates / Q000009:adverse effects*; D012306:Risk; D013997:Time Factors; D014481:United States
D000893:Anti-Inflammatory Agents; D010654:Phenylbutyrates; D011422:Propionates; C010725:fenbufen; D001241:Aspirin; D007213:Indomethacin