A novel glycosphingolipid that may participate in embryo inversion in Volvox carteri.
Mouse monoclonal antibody 4-I-244 detects a developmentally regulated antigen in embryos of Volvox carteri and inhibits specifically the morphogenetic process of inversion (the process by which the embryo turns inside out). Antigen 4-I-244 was chemically characterized as a complex phytosphingolipid containing the neutral sugars xylose, galactose, and glucose as well as inositol and phosphate.
D000911:Antibodies, Monoclonal; D002462:Cell Membrane / Q000276:immunology / Q000502:physiology; D000460:Chlorophyta / Q000276:immunology / Q000502:physiology* / Q000648:ultrastructure; D005455:Fluorescent Antibody Technique; D006028:Glycosphingolipids / Q000032:analysis / Q000276:immunology / Q000502:physiology*; D009024:Morphogenesis
D000911:Antibodies, Monoclonal; D006028:Glycosphingolipids