Recognition of polymorphic monocyte antigens.
Sera from multiparous women and renal transplant recipients were screened for the presence of anti-monocyte antibodies. Reactions caused by anti-HLA antibodies were excluded by using panel cells that were HLA-compatible with the antibody producers. Six sera with monocyte-specific antibodies were identified, and at least two monocyte-specific (probably allelic) antigens could be recognized. The perspective of the clinical significance of typing for monocyte-specific antigens is discussed.
D000936:Antigen-Antibody Complex; D001402:B-Lymphocytes / Q000276:immunology; D005260:Female; D008040:Genetic Linkage; D006680:HLA Antigens / Q000032:analysis / Q000235:genetics*; D006801:Humans; D016030:Kidney Transplantation; D009000:Monocytes / Q000276:immunology*; D011110:Polymorphism, Genetic; D011247:Pregnancy; D013601:T-Lymphocytes / Q000276:immunology; D013696:Temperature
D000936:Antigen-Antibody Complex; D006680:HLA Antigens