title: The cephalosporin antibiotics in pediatric therapy.
abstract: The cephalosporins have been available for clinical use for nearly 20 years and a large number is presently marketed, including drugs with a wide range of different pharmacokinetic and microbiologic properties. While some of these agents have certain specific uses in which they excel, the cephalosporins have not replaced older antibiotics but do provide the physician with a broader range of choices for the treatment of many infections, allowing greater individualization of therapy.
mesh_terms: D000284:Administration, Oral; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D002435:Cefamandole / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002437:Cefazolin / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002441:Cefsulodin / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002505:Cephacetrile / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002506:Cephalexin / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002509:Cephaloridine / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002511:Cephalosporins / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002512:Cephalothin / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002513:Cephamycins / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002515:Cephradine / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007273:Injections, Intramuscular
chemical_list: D002511:Cephalosporins; D002513:Cephamycins; D002435:Cefamandole; D002515:Cephradine; D002505:Cephacetrile; D002437:Cefazolin; D002509:Cephaloridine; D002506:Cephalexin; D002441:Cefsulodin; D002512:Cephalothin