title: Complications following laryngectomy.
abstract: The complications following 100 consecutive laryngectomies performed at our hospital during a recent 18-month period are reviewed. The complication rates for total laryngectomy (63 patients) and extended laryngectomy (37 patients) were 19% and 49%, respectively, while the fistula rates were 8% and 27%, respectively. These rates were influenced primarily by the extent of surgery and the type of reconstruction, which during this interval included primary closure, pectoralis major myocutaneous flap, or gastric transposition. In comparison to our previous study, when the deltopectoral flap was used for patching the pharynx, the fistula rate for extended laryngectomy has decreased as a result of our use of myocutaneous flaps and greater experience with gastric transposition. Currently, we use the pectoralis major myocutaneous flap for pharyngeal repair if the mucosa would otherwise be closed under tension. All circumferential defects are repaired with a gastric transposition.
mesh_terms: D000328:Adult; D000368:Aged; D002437:Cefazolin / Q000627:therapeutic use; D005260:Female; D005402:Fistula / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007818:Laryngeal Diseases / Q000453:epidemiology / Q000209:etiology; D007822:Laryngeal Neoplasms / Q000150:complications / Q000601:surgery; D007825:Laryngectomy / Q000009:adverse effects* / Q000379:methods; D008297:Male; D008875:Middle Aged; D010611:Pharyngectomy; D011182:Postoperative Care; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D011292:Premedication; D013536:Suture Techniques
chemical_list: D002437:Cefazolin