title: No additive effect of tranexamic acid and naproxen on corneal deswelling. A study on oedema after uncomplicated intracapsular cataract extraction with anterior chamber lens implantation.
abstract: The influence of systemic antifibrinolytic and antiprostaglandin medication on post-operative central corneal thickness was studied. Thirty patients underwent uncomplicated intracapsular cataract extraction with implantation of anterior chamber lens. The patients received either tranexamic acid, naproxen or both. The post-operative oedema did not differ significantly between the three groups studied. Models for studying changes in central corneal thickness are discussed. A review of the influence of drugs on corneal thickness is presented.
mesh_terms: D000368:Aged; D002387:Cataract Extraction; D002986:Clinical Trials as Topic; D003315:Cornea / Q000187:drug effects*; D003316:Corneal Diseases / Q000517:prevention & control*; D003509:Cyclohexanecarboxylic Acids / Q000627:therapeutic use*; D004487:Edema / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007910:Lenses, Intraocular; D008297:Male; D009288:Naproxen / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000517:prevention & control; D014148:Tranexamic Acid / Q000627:therapeutic use*
chemical_list: D003509:Cyclohexanecarboxylic Acids; D009288:Naproxen; D014148:Tranexamic Acid