Controlled trial of aspirin in cerebral ischemia: an addendum.
Patients (303) who had had carotid territory transient ischemic attacks were randomly assigned to aspirin or placebo treatments. Patients with amaurosis fugax responded as well to aspirin as those with hemisphere events. Patients with lesions of the appropriate carotid artery responded better to aspirin therapy than patients with no lesion or an occlusion. The aspirin effect was the same across all risk-factor groups. Smoking had no effect on clinical outcome.
D001241:Aspirin / Q000627:therapeutic use*; D001766:Blindness / Q000188:drug therapy; D002340:Carotid Artery Diseases / Q000188:drug therapy; D002561:Cerebrovascular Disorders / Q000188:drug therapy; D002986:Clinical Trials as Topic; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D002546:Ischemic Attack, Transient / Q000150:complications / Q000188:drug therapy*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications; D010919:Placebos; D011897:Random Allocation; D012306:Risk
D010919:Placebos; D001241:Aspirin