Cerebral toxoplasmosis after renal transplantation. Case report.
A 19-year-old immunosuppressed male patient, after renal transplantation, developed at the 10th postoperative day (p.d.) fever, anemia hepatosplenomegaly and plaquetopenia; this condition deteriorated progressively and was complicated by drowsiness and generalized convulsions which persisted until the death at the 29th p.d. Autopsy revealed acute encephalitis characterized by multiple disseminated small lesions in the brain, containing cysts and trophozoites of Toxoplasma gondii. The diagnosis was not done during life, as occurred with most of previously reported cases, a fact that points to the necessity of preventive controlling measures of these patients before the institution of immunosuppressive measures.
D000208:Acute Disease; D000328:Adult; D004660:Encephalitis / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation; D008297:Male; D014122:Toxoplasma; D014123:Toxoplasmosis / Q000175:diagnosis / Q000209:etiology*