title: Patterns and correlates of genetic variation in South Amerindians.
abstract: Gene frequency data from six polymorphic blood group systems in 70 South American Indian populations are used to derive synthetic gene frequency maps that document the geographical pattern of genetic variation. Additional analyses are directed toward the elucidation of mechanisms that give rise to or maintain the observed distributions. Variables of local ecology do not appear to explain gene frequency distributions in South America. Instead, local isolation and the action of stochastic forces appears to be the most parsimonious explanation of the observed geographical patterns. This is distinctly different from the geographical patterns of genetic variation seen in other continents.
mesh_terms: D000483:Alleles; D001789:Blood Group Antigens / Q000235:genetics; D002980:Climate; D004812:Epidemiologic Methods; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D007199:Indians, South American; D007256:Information Systems; D013020:South America
chemical_list: D001789:Blood Group Antigens