The neutralization of hydroxyl radical by silibin, sorbinil and bendazac.
The compounds silibin, sorbinil and bendazac act as hydroxyl radical scavengers, when the hydroxyl radical is generated by the Fenton reaction. Hydroxyl was detected by the degradation of deoxyribose. The Authors discuss the possibility that the scavenger activities of those compounds may explain, at least in part, their therapeutic activity.
D000975:Antioxidants; D003855:Deoxyribose; D005609:Free Radicals; D006878:Hydroxides; D007093:Imidazoles; D048289:Imidazolidines; D066298:In Vitro Techniques; D007191:Indazoles; D012838:Silymarin
D000975:Antioxidants; D005609:Free Radicals; D006878:Hydroxides; D007093:Imidazoles; D048289:Imidazolidines; D007191:Indazoles; D012838:Silymarin; D003855:Deoxyribose; C026411:sorbinil; C000123:bendazac