title: Renal biopsy in Saudi children with nephrotic syndrome not responsive to corticosteroid: a preliminary report.
abstract: Percutaneous renal biopsy was done in 25 Saudi children whose nephrotic syndrome did not respond to prednisolone. The histologic diagnosis was mesangial proliferative glomerulonephritis in 11 cases; an additional two biopsies had features of both mesangial proliferative glomerulonephritis and focal segmental glomerulosclerosis. Immunofluorescence was abnormal in 16 out of 21 patients, with IgM as the most frequently detected immunogen.
mesh_terms: D000293:Adolescent; D001485:Basement Membrane / Q000473:pathology; D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D005260:Female; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000473:pathology; D005923:Glomerulosclerosis, Focal Segmental / Q000473:pathology; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology*; D008297:Male; D009402:Nephrosis, Lipoid / Q000473:pathology; D009404:Nephrotic Syndrome / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use*; D012529:Saudi Arabia
chemical_list: D011239:Prednisolone