[Cyclosporin A in the treatment of pemphigus foliaceus and pemphigus erythematosus].
We present the cases of two female patients with pemphigus foliaceus and pemphigus erythematosus, respectively, who did not respond to long-term azathioprine and prednisone treatment in high dosages. In both patients the skin condition improved nearly completely after therapy with cyclosporine A (3.5-6.5 mg/kg per day) in combination with prednisone (7.5-10 mg every 2 days). We did not observe any side-effects during 1 year of this therapy.
D003176:Complement C3 / Q000378:metabolism; D003524:Cyclosporins / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D008875:Middle Aged; D010392:Pemphigus / Q000188:drug therapy* / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D012867:Skin / Q000473:pathology
D003176:Complement C3; D003524:Cyclosporins; D007074:Immunoglobulin G; D011241:Prednisone
Cyclosporin A in der Behandlung von Pemphigus foliaceus und Pemphigus erythematosus.