[Early changes in the lymphocyte surface membrane of rats after whole-body irradiation with neutrons and gamma rays].
Biochemical changes in lymphocyte plasma membranes were studied 3 and 18 h after whole-body exposure of rats to neutrons and gamma-rays at doses from 2 to 6 Gy. It was shown that fast neutrons, with an average energy of 1.5-2.0 MeV, increased the rate of lipid peroxidation more markedly than gamma-rays did. In addition, there was an increase in the number of free aminogroups on the thymocyte surface. Dose- and time-dependent parameters of changes in the aminogroup content on the cellular surface were quantitatively different after the effect of radiation with different LET.
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism / Q000528:radiation effects; D005720:Gamma Rays; D008054:Lipid Peroxides / Q000378:metabolism / Q000528:radiation effects; D008214:Lymphocytes / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism / Q000528:radiation effects; D009502:Neutrons; D017830:Octoxynol; D011092:Polyethylene Glycols / Q000494:pharmacology; D011732:Pyridoxal Phosphate / Q000378:metabolism; D051381:Rats; D012062:Relative Biological Effectiveness; D014916:Whole-Body Irradiation
D008054:Lipid Peroxides; D008563:Membrane Lipids; D011092:Polyethylene Glycols; D011732:Pyridoxal Phosphate; D017830:Octoxynol
Rannie izmeneniia membran kletochnoĭ poverkhnosti limfotsitov u krys posle obshchego vozdeĭstviia neĭtronov i gamma-izlucheniia.