Long-term ocular manifestations in nephropathic cystinosis.
Eight nephropathic-cystinotic patients having undergone renal transplantation seven to 14 years previously were studied. Serious ocular complications were noted in four of the eight cases not previously reported. These included posterior synechiae, deposition of crystals on the anterior lens surface, and decreased visual acuity accompanied by impaired visual function, as measured by psychophysical and electrodiagnostic tests when possible.
D000293:Adolescent; D000328:Adult; D002648:Child; D003315:Cornea / Q000473:pathology; D003543:Cysteamine / Q000627:therapeutic use; D003554:Cystinosis / Q000150:complications* / Q000235:genetics / Q000473:pathology / Q000503:physiopathology; D004596:Electroretinography; D005128:Eye Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007498:Iris / Q000473:pathology; D007674:Kidney Diseases / Q000209:etiology* / Q000235:genetics / Q000601:surgery; D016030:Kidney Transplantation; D007903:Lens Capsule, Crystalline / Q000473:pathology; D008297:Male; D012160:Retina / Q000473:pathology / Q000503:physiopathology; D014792:Visual Acuity
D003543:Cysteamine