title: Subpopulations of circulating lymphocytes in adults with coeliac disease.
abstract: Circulating lymphocytes were enumerated in 25 patients with coeliac disease and in 24 healthy donors by immunofluorescent staining using monoclonal antibodies for T cell surface phenotypic markers T11 (mature), T4 (helper) and T8 (suppressor) or polyvalent antisera for surface immunoglobulins (B cells). Proportions of peripheral T and B cells and percentages and ratio of T cell subsets in coeliac disease were not significantly different from those in controls. Individual ratios of helper to suppressor T cells did not correlate with disease activity or with keeping the diet.
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D001402:B-Lymphocytes / Q000145:classification* / Q000276:immunology; D002446:Celiac Disease / Q000097:blood*; D005260:Female; D005455:Fluorescent Antibody Technique; D005983:Glutens / Q000276:immunology / Q000378:metabolism; D006801:Humans; D008297:Male; D013601:T-Lymphocytes / Q000145:classification* / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D005983:Glutens