title: Induction of early seasonal sensitivity to melatonin in Suffolk-Cross ewes.
abstract: Anoestrous Suffolk-Cross ewes can be induced into early seasonal ovarian activity by administration of melatonin at the appropriate time of day or by melatonin implants. This treatment is successful if commenced in June, but not earlier in April or May and suggests that a critical period of long days may be necessary before artificial short-day melatonin profiles act as winter time-cues. We have investigated whether the lack of sensitivity to melatonin in April could be overcome in ewes in which breeding activity had been artificially moved forward the previous season. The results indicate that this was indeed the case and that the breeding season in untreated ewes which also previously experienced an early induced breeding season reverted to the normal timing for the Suffolk-Cross breed.
mesh_terms: D000818:Animals; D004343:Drug Implants; D004971:Estrus / Q000187:drug effects*; D005260:Female; D008550:Melatonin / Q000494:pharmacology*; D010053:Ovary / Q000187:drug effects / Q000502:physiology; D010507:Periodicity; D011374:Progesterone / Q000097:blood; D012016:Reference Values; D012621:Seasons; D012756:Sheep
chemical_list: D004343:Drug Implants; D011374:Progesterone; D008550:Melatonin