title: Fungal infections of the CNS.
abstract: Most CNS fungal infections can be divided into those that occur in normal hosts and those that occur in the immunosuppressed host. Cryptococcal infection, however, is common in both groups. The usual clinical presentation of a CNS fungal infection is chronic headache and mental status change. The CSF shows a lymphocytic meningitis with low sugar and high protein. Amphotericin B remains the drug of choice for most CNS fungal infections.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000935:Antifungal Agents / Q000627:therapeutic use; D001759:Blastomycosis / Q000150:complications / Q000175:diagnosis; D002493:Central Nervous System Diseases / Q000150:complications / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D002555:Cerebrospinal Fluid / Q000032:analysis / Q000166:cytology; D003047:Coccidioidomycosis / Q000150:complications / Q000175:diagnosis; D003453:Cryptococcosis / Q000150:complications / Q000382:microbiology; D048909:Diabetes Complications; D006660:Histoplasmosis / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007108:Immune Tolerance; D009091:Mucormycosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000635:transmission; D008271:Mycetoma / Q000150:complications; D009181:Mycoses / Q000150:complications / Q000382:microbiology* / Q000473:pathology / Q000628:therapy
chemical_list: D000935:Antifungal Agents