The use of naproxen in controlling postoperative pain in podiatric surgery.
The study was conducted with 110 patients admitted to Sheridan Park Hospital to determine the efficacy of the nonsteroidal anti-inflammatory drug, naproxen, in relieving postoperative pain. Aspirin, as well as compounds classified as nonsteroidal, anti-inflammatory drugs (NSAID), such as naproxen, are known to inhibit synthesis of certain prostaglandins that are involved in the inflammation process. This is the cause of a significant percentage of postoperative pain.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005534:Foot Diseases / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009288:Naproxen / Q000008:administration & dosage / Q000627:therapeutic use*; D010149:Postoperative Pain / Q000188:drug therapy / Q000517:prevention & control*; D011292:Premedication; D011453:Prostaglandins / Q000502:physiology; D011897:Random Allocation
D011453:Prostaglandins; D009288:Naproxen