Antimutagenicity of extracts from crude drugs in Chinese medicines.
The antimutagenicity of extracts from crude drugs was studied by the Ames bioassay system. The crude drugs chosen were medical plants used very frequently as Chinese medicines. Each crude drug was extracted with hot water similar to the method of Chinese medical treatment. Antimutagenicity of the extract was found with 4 kinds of crude drugs, Paeoniae radix, Bupleuri radix, Hoelen and Glycyrrhizae radix. Each extract of the crude drug showed a different type of antimutagenic action from the others.
D006801:Humans; D008516:Medicine, Chinese Traditional; D008518:Medicine, East Asian Traditional; D009152:Mutagenicity Tests; D009153:Mutagens / Q000037:antagonists & inhibitors*; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D012486:Salmonella typhimurium / Q000187:drug effects
D009153:Mutagens; D010936:Plant Extracts