title: [Proteolysis in the cells of malignant human and animal tumors].
abstract: The data concerning proteolytic enzymes in human and animal malignant tumours are reviewed. The activity of these proteinases, its changes in the course of the disease, intracellular localization and secretion into the extracellular space and blood are discussed. The role of proteolytic enzymes including the role of plasminogen activator in tumour progress and during the metastasis development is considered.
mesh_terms: D000818:Animals; D002417:Cattle; D002462:Cell Membrane / Q000201:enzymology; D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D004789:Enzyme Activation; D006801:Humans; D051379:Mice; D009362:Neoplasm Metastasis; D009363:Neoplasm Proteins / Q000378:metabolism; D009369:Neoplasms / Q000201:enzymology* / Q000276:immunology; D009374:Neoplasms, Experimental / Q000201:enzymology* / Q000276:immunology; D010447:Peptide Hydrolases / Q000276:immunology / Q000378:metabolism*; D010960:Plasminogen Activators / Q000502:physiology; D051381:Rats
chemical_list: D009363:Neoplasm Proteins; D010447:Peptide Hydrolases; D010960:Plasminogen Activators
vernacular_title: Proteoliz v kletkakh zlokachestvennykh opukholeĭ cheloveka i zhivotnykh.