Pipemidic acid, a new treatment for recurrent urinary tract infection in small animals.
A new chemotherapeutic agent, pipemidic acid, was used to treat 14 dogs and 2 cats with recurrent urinary tract infection caused by multiresistent strains of Escherichia coli and Proteus spp. Bacterial culture of the urine after treatment revealed disappearance of the microorganisms in all patients. It is concluded that pipemidic acid is a promising chemotherapeutic agent for urinary tract infections caused by multiresistant E. coli and Proteus spp., with the condition that bacterial culture during the course of treatment is obligatory.
D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000662:veterinary*; D009539:Nicotinic Acids / Q000627:therapeutic use*; D010876:Pipemidic Acid / Q000627:therapeutic use*; D011512:Proteus Infections / Q000188:drug therapy / Q000662:veterinary*; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000662:veterinary*
D009539:Nicotinic Acids; D010876:Pipemidic Acid