title: Diclofenac sodium in the treatment of primary nocturnal enuresis: double-blind crossover study.
abstract: The prostaglandin synthesis inhibitor diclofenac sodium has been compared with a placebo in the treatment of primary nocturnal enuresis in a double-blind crossover trial. Twenty patients were entered: 14 female, six male; age range 6-17 years. The results showed that diclofenac sodium was significantly more effective than placebo in the treatment of nocturnal enuresis.
mesh_terms: D000293:Adolescent; D002648:Child; D002986:Clinical Trials as Topic; D004008:Diclofenac / Q000627:therapeutic use*; D004311:Double-Blind Method; D004775:Enuresis / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D011312:Pressure; D011453:Prostaglandins / Q000502:physiology; D014521:Urethra / Q000503:physiopathology; D001743:Urinary Bladder / Q000503:physiopathology
chemical_list: D011453:Prostaglandins; D004008:Diclofenac