Urinary pathogenicity of Proteus mirabilis strains isolated from faeces or urine.
Urinary and faecal isolates of Proteus mirabilis were studied with respect to a number of bacterial properties as possible virulence factors in the pathogenesis of urinary tract infections: experimental virulence in a mouse model, haemolysin production, haemagglutinating properties, hydrophobicity of the bacterial surface, sensitivity to the bactericidal effect of human serum, serotype and cell invasiveness. Urinary isolates were slightly more virulent than faecal isolates in the mouse model. No other significant differences were found between both groups. So urinary strains seem to be selected from the faecal reservoir mainly on the basis of their prevalence in the faeces and not on the basis of the possession of particular virulence factors.
D000818:Animals; D001437:Bacteriuria / Q000382:microbiology*; D001770:Blood Bactericidal Activity; D005243:Feces / Q000382:microbiology*; D006384:Hemagglutination; D006461:Hemolysis; D006801:Humans; D008297:Male; D051379:Mice; D011512:Proteus Infections / Q000382:microbiology*; D011513:Proteus mirabilis / Q000145:classification / Q000302:isolation & purification / Q000472:pathogenicity*; D012703:Serotyping; D014774:Virulence