title: Effects of exogenous iron on Escherichia coli septicemia of turkeys.
abstract: The effect of inoculation with Escherichia coli on serum iron concentrations of turkeys and the effect of exogenous iron, as ferric ammonium citrate, on E coli septicemia in turkeys were determined. Inoculation of air sacs with E coli produced hypoferremia in 18-day-old turkeys. Administration of iron with E coli significantly (P less than 0.01) increased mortality, frequency and degree of bacteremia, and severity of lesions in inoculated turkeys, compared with those in turkeys given E coli but not given iron. Similar results were seen whether iron was inoculated at the same location as E coli or at a different location.
mesh_terms: D000818:Animals; D004927:Escherichia coli Infections / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D005290:Ferric Compounds / Q000494:pharmacology*; D007501:Iron / Q000097:blood / Q000494:pharmacology*; D011201:Poultry Diseases / Q000503:physiopathology*; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D012016:Reference Values; D018805:Sepsis / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D013997:Time Factors; D014422:Turkeys
chemical_list: D005290:Ferric Compounds; D000644:Quaternary Ammonium Compounds; D007501:Iron; C013531:ferric ammonium citrate