title: An ancient developmental induction: heat-shock proteins induced in sporulation and oogenesis.
abstract: Every eukaryotic and prokaryotic organism tested to date synthesizes a small number of heat-shock proteins in response to heat and other forms of stress. A particular pattern of heat-shock gene expression was observed during ascospore development in Saccharomyces: heat-shock proteins hsp26 and hsp84 were strongly induced nor inducible by heat shock. Instead, two proteins related to hsp70 were induced. A strikingly similar pattern of expression occurs during oogenesis in Drosophila, suggesting that it may be one of the earliest developmental pathways to evolve in eukaryotic cells.
mesh_terms: D004330:Drosophila / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000096:biosynthesis*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D013172:Spores, Fungal
chemical_list: D006360:Heat-Shock Proteins; D012333:RNA, Messenger