title: Pretibial epidermolysis bullosa. Successful therapy with a skin graft.
abstract: A patient with pretibial epidermolysis bullosa was successfully treated with a skin graft. Ultrastructural examination revealed a decreased number of and rudimentary anchoring fibrils (AFs) in the pretibial area in contrast to normal AFs in the grafted skin obtained from a nonpredilection site. Our results indicate the importance of AFs in the pathogenesis of pretibial epidermolysis bullosa.
mesh_terms: D000293:Adolescent; D001485:Basement Membrane / Q000276:immunology; D002648:Child; D004820:Epidermolysis Bullosa / Q000145:classification / Q000276:immunology / Q000473:pathology / Q000601:surgery*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007866:Leg / Q000473:pathology; D012867:Skin / Q000648:ultrastructure; D016038:Skin Transplantation