Lipid regulation: a clinician's view of patient management.
Practicing physicians now have the capability as well as the responsibility to treat hyperlipidemia. Recent conclusive trials have demonstrated the link between lipid elevations and coronary heart disease, as well as the likelihood of reducing coronary heart disease risk by lowering blood lipids via diet and/or drug intervention. Screening criteria for hyperlipidemia in normal patients and in special patient subgroups are described, and recommendations for treatment are proposed. The diet recommended by the American Heart Association--which limits fat intake to 25% to 30% of all calories in a 1:1:1 ratio of saturated, monounsaturated and polyunsaturated fats, and limits cholesterol to less than 300 mg/day--is discussed. Guidelines are suggested for drug therapy with lipid-lowering agents to reduce abnormal lipid levels when diet alone proves insufficient after 2- to 3-month trial.
D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000517:prevention & control*; D003956:Dialysis; D004041:Dietary Fats / Q000008:administration & dosage*; D006801:Humans; D006949:Hyperlipidemias / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control*; D008403:Mass Screening; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D012306:Risk; D014280:Triglycerides / Q000097:blood
D002791:Cholesterol, Dietary; D004041:Dietary Fats; D014280:Triglycerides; D002784:Cholesterol