title: Advanced instrumentation and strategies for metabolic profiling.
abstract: This review summarizes the instrumental techniques applicable for metabolic profiling analysis. Since its origin with the work of Roger Williams, use has been made of planar chromatography, column liquid chromatography, electrophoresis, gas-liquid chromatography, and mass spectrometry to obtain analyte patterns. Strategies for the analysis of various metabolites including organic acids, steroids, drugs, bile acids, carbohydrates, and proteins are discussed.
mesh_terms: D000818:Animals; D002845:Chromatography / Q000295:instrumentation*; D002851:Chromatography, High Pressure Liquid; D002852:Chromatography, Ion Exchange; D002854:Chromatography, Paper; D002855:Chromatography, Thin Layer; D004586:Electrophoresis; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D013058:Mass Spectrometry; D008660:Metabolism; D004364:Pharmaceutical Preparations / Q000032:analysis*; D013054:Spectrophotometry, Atomic
chemical_list: D004364:Pharmaceutical Preparations