[Bone marrow autotransplantation as a factor modifying the process of hematopoietic tissue recovery in irradiated guinea pigs].
Guinea pigs were subjected to myeloexfusion 30-90 min before gamma-irradiation with a superlethal dose of 8 Gy. Immediately after irradiation, the bone marrow (4 X 10(7) cells) was autotransplanted. The automyelotransplantation provided a pronounced stimulation of haemopoiesis and substantially shortened the time of its regeneration. The myeloexfusion in some of the exposed control animals had a beneficial effect in their resistance and blood system recovery.
D000818:Animals; D016026:Bone Marrow Transplantation; D002452:Cell Count; D003114:Colony-Forming Units Assay; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006168:Guinea Pigs; D006412:Hematopoietic Stem Cells / Q000473:pathology / Q000528:radiation effects*; D008297:Male; D011833:Radiation Injuries, Experimental / Q000473:pathology / Q000628:therapy*; D013154:Spleen / Q000473:pathology / Q000528:radiation effects; D013997:Time Factors; D014182:Transplantation, Autologous
Autotransplantatsiia kostnogo mozga kak faktor, modifitsiruiushchiĭ protsessy vosstanovleniia krovetvornoĭ tkani u obluchennykh morskikh svinok.