title: [Controlled study of the analgesic effect and tolerability of buprenorphine in cancer patients].
abstract: The analgesic efficacy and tolerability of a morphine agonist-antagonist buprenorphine are evaluated. The drug is compared to pentazocin. For this purpose, the drugs were randomly administered to 42 patients suffering from pain caused by advanced cancer. Buprenorphine demonstrated a significantly higher analgesic effect than pentazocin and was better tolerated.
mesh_terms: D002047:Buprenorphine / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D009019:Morphinans / Q000627:therapeutic use*; D009369:Neoplasms / Q000188:drug therapy*; D010148:Intractable Pain / Q000188:drug therapy*; D010423:Pentazocine / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D009019:Morphinans; D002047:Buprenorphine; D010423:Pentazocine
vernacular_title: Studio controllato sull'effetto analgesico e sulla tollerabilità della buprenorfina, in pazienti affetti da neoplasia.