The role of glucose in hemodialysis: the effects of glucose-free dialysate.
Glucose-free dialysate has been traditionally used in patients on chronic hemodialysis, reportedly without any side effects. Although hypoglycemia is not produced, several other metabolic changes must occur to maintain the euglycemic state. We studied ten patients on chronic hemodialysis using both a glucose-free bath and a glucose bath. Without glucose, a drop in osmolality of 20 mosm/kg H2O occurred, whereas a change of only 10 mosm/kg H2O was observed using a glucose bath. Abnormal EEG changes were observed after dialysis without glucose that were not present or were minimal with a glucose bath.
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001835:Body Weight; D002986:Clinical Trials as Topic; D004569:Electroencephalography; D004573:Electrolytes / Q000008:administration & dosage / Q000097:blood; D005947:Glucose / Q000494:pharmacology*; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D009997:Osmotic Pressure; D011897:Random Allocation; D006435:Renal Dialysis; D013997:Time Factors
D004573:Electrolytes; D013006:Growth Hormone; D005947:Glucose