Resistant hypertension associated with a renin-producing ovarian Sertoli cell tumor.
A 17-year-old girl with refractory, but nonmalignant, hypertension and hypokalemia is presented. A state of primary hyperreninism and secondary hyperaldosteronism was found to exist, together with a renin-producing Sertoli cell ovarian tumor. Upon removal of the tumor, this patient attained both a normotensive and a normokalemic state. A brief review is given of renal and nonrenal renin-producing tumors.
D000293:Adolescent; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D010051:Ovarian Neoplasms / Q000150:complications* / Q000378:metabolism; D012083:Renin / Q000378:metabolism*; D012707:Sertoli Cell Tumor / Q000150:complications* / Q000378:metabolism
D012083:Renin