Neuropeptide Y and the innervation of the human eye.
Using the indirect immunohistochemical technique, neuropeptide Y as found in human ocular nerves. While limbal blood vessels were innervated and a few nerves were seen in the trabecular meshwork, the cornea proper contained no immunoreactive nerve fibers. Neuropeptide Y-like immunoreactive nerves supplied the iris dilator muscle and, to a lesser extent, the iris sphincter. Immunoreactive nerve fibers were present within the ciliary muscle and the ciliary processes. Neuropeptide Y-like immunoreactive choroidal nerve fibers were frequently associated with blood vessels. The apposition of immunoreactive nerve fibers and melanocytes occurred throughout the uvea. The distribution of neuropeptide Y-like immunoreactive nerves in the eye closely parallels the adrenergic innervation. Evidence linking neuropeptide Y to the ocular sympathetic innervation is discussed.
D000293:Adolescent; D000328:Adult; D002648:Child; D002829:Choroid / Q000294:innervation; D002924:Ciliary Body / Q000294:innervation; D003315:Cornea / Q000294:innervation; D005123:Eye / Q000032:analysis / Q000294:innervation*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007498:Iris / Q000294:innervation; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000032:analysis; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009478:Neuropeptide Y; D014129:Trabecular Meshwork / Q000294:innervation
D009419:Nerve Tissue Proteins; D009478:Neuropeptide Y