Cerebrospinal fluid neuropeptide Y in depression and schizophrenia.
Neuropeptide Y (a recently discovered brain peptide that is colocalized with norepinephrine within some adrenergic central nervous system neurons) was measured in the cerebrospinal fluid (CSF) from patients with major affective disorder, chronic schizophrenia, and in normal volunteers. No differences between diagnostic groups were found, suggesting that if this neuropeptide is involved in the pathogenesis of these disorders, an abnormality is not detectable in the CSF.
D015415:Biomarkers / Q000134:cerebrospinal fluid*; D003866:Depressive Disorder / Q000134:cerebrospinal fluid*; D005260:Female; D005476:Fluphenazine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009478:Neuropeptide Y / Q000134:cerebrospinal fluid*; D012016:Reference Values; D012559:Schizophrenia / Q000134:cerebrospinal fluid* / Q000188:drug therapy
D015415:Biomarkers; D009478:Neuropeptide Y; D005476:Fluphenazine