Treatment of pregnant insulin-dependent diabetic women.
The treatment of 620 insulin-dependent diabetic pregnant women is reported. The goal of treatment was to achieve a normal blood glucose concentration as soon as possibly during early, or even before pregnancy. When intensified conventional insulin therapy was started before conception, about 88% of the patients achieved normal blood glucose levels during the first weeks of pregnancy. In only about 20% of the pregnant diabetics without intensified preconceptional treatment a normal blood glucose level was obtained during their first hospitalization in pregnancy. The rate of congenital malformations was 1.1% in the former and 7.1% in the latter group.
D001786:Blood Glucose / Q000032:analysis; D000013:Congenital Abnormalities / Q000209:etiology; D003922:Diabetes Mellitus, Type 1 / Q000628:therapy*; D004038:Diet, Reducing; D002149:Energy Intake; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011254:Pregnancy in Diabetics / Q000150:complications / Q000628:therapy*
D001786:Blood Glucose; D007328:Insulin