title: Effect of application of polyvinilidine plates on the dorsal spinous processes of dogs.
abstract: Anecdotal comments in the literature suggest that spinous fracture many weeks after application of polyvinilidine plates to the dorsal spinous processes of dogs may be due to associated adverse vascular changes. This study was undertaken to evaluate that hypothesis. Large size Lubra plates were cut to the appropriate length and applied to the dorsal spines of vertebrae L3 and L4. Vertebrae L2 and L5 served as operated controls. Vertebrae L1 and L6 served as unoperated normals. Two dogs were euthanized 1 week postoperatively, and three dogs each at 4, 8, and 12 weeks. The effect of the plate on the dorsal spinous processes was evaluated using microangiography and correlated histology. There was no apparent change in vascular architecture associated with plate application, nor with surgery alone, at any time interval. There did appear to be a time dependent loss of bone associated with plate application, indicating a change in the relative balance of osteoblastic and osteoclastic activity, and altered bone turnover.
mesh_terms: D000792:Angiography / Q000662:veterinary; D000818:Animals; D001860:Bone Plates / Q000009:adverse effects / Q000662:veterinary*; D004285:Dogs / Q000601:surgery*; D011145:Polyvinyls; D013131:Spine / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery*
chemical_list: D011145:Polyvinyls