title: Synthesis of alpha-thiophenylglycine peptides. Novel peptide substrates useful in the study of microbial peptide transport.
abstract: The synthesis of peptides useful for the investigation of microbial peptide transport is reported. These peptides, L-alanyl-L-2-thiophenylglycine (Ala-alpha-TPG), L-alanyl-L-2-thiophenylglycyl-L-alanine (Ala-alpha-TPG-Ala) and L-alanyl-L-alanyl-L-2-thiophenylglycine (Ala-Ala-alpha-TPG), contain a phenylthio group attached to the alpha carbon of glycine.
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001692:Biological Transport; D002176:Candida albicans / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004151:Dipeptides / Q000138:chemical synthesis* / Q000494:pharmacology; D004926:Escherichia coli / Q000378:metabolism; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D009842:Oligopeptides / Q000138:chemical synthesis*; D009904:Optical Rotation; D010455:Peptides / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D004151:Dipeptides; D007202:Indicators and Reagents; D009842:Oligopeptides; D010455:Peptides