title: [Tissue and blood ferritins and isoferritins].
abstract: Ferritins which can store excess iron are localised principally in tissue. Ferritins have on apoprotein shell which is composed of 24 sub-units, from 2 types of sub-units: "H" (molecular weight about 21 000) and "L" (molecular weight about 19 000) that assemble in different proportions and give multiple forms. Protein pattern depends on tissue nature. Since 1972, radio-immunology assays have shown very low serum ferritin levels. There is a good correlation between these levels and the amount of storage iron in the body. However it was demonstrated that elevation of serum ferritin could also occur without iron metabolism trouble by various mechanisms.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D005293:Ferritins / Q000097:blood / Q000378:metabolism* / Q000502:physiology; D006486:Hemosiderosis / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D007501:Iron / Q000378:metabolism; D009369:Neoplasms / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D005293:Ferritins; D007501:Iron
vernacular_title: Ferritines et isoferritines tissulaires et circulantes.