Localization of AT-rich sequences at the nuclear matrix.
After culture with 3H-thymidine murine erythroleukemia cells with more sites of DNA attached to the nuclear matrix have more labeled thymidine in their matrix-bound DNA than in their total DNA than do cells with fewer attachment sites. This indicates that the average attachment site sequence is enriched in A + T base pairs.
D000818:Animals; D001483:Base Sequence; D002467:Cell Nucleus / Q000378:metabolism*; D004261:DNA Replication; D004915:Leukemia, Erythroblastic, Acute / Q000378:metabolism*; D051379:Mice; D011865:Radioisotope Dilution Technique; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D014316:Tritium; D013936:Thymidine