[Prognostic significance of biochemical and sonographic findings in hemorrhage in early pregnancy].
In order to classify events of bleeding in early pregnancy (7th-16th week of pregnancy), an ultrasonic examination was carried out on 72 pregnant women, as well as tests establishing the HCG-secretion in the early morning urine and the progesterone level in the serum before commencing hormone therapy. The collected medical evidence was compared with standard curves. In order to test its prognostic validity, it was related to the termination of the pregnancy. In cases of miscarriage, the placenta was examined histologically and the progesterone level decrease registered over 48 hours. In 34 women, the pregnancy ended with a birth; in 26 (76.5%) of these cases the progesterone values were with the normal area. The HCG-secretion was normal in 25 (74.3%) patients. The sonographic classification indicated an intact pregnancy in every case. In 38 cases the pregnancy was disturbed. In this group of patients, the progesterone level in 36 cases (94.8%) and the HCG values in 27 patients (71.1%) were below the normal. Signs of life were absent in 37 pregnancies (97.4%) in the ultrasonic examination. By virtue of the statistical evaluation of this data, a high reliability can be attributed to the sonographic evidence with regard to the correct prognosis for bleeding in early pregnancy.
D000293:Adolescent; D000328:Adult; D006063:Chorionic Gonadotropin / Q000652:urine*; D005260:Female; D005313:Fetal Death / Q000175:diagnosis; D005328:Fetal Viability; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis* / Q000378:metabolism; D011374:Progesterone / Q000097:blood*; D011863:Radioimmunoassay; D014463:Ultrasonography; D014592:Uterine Hemorrhage / Q000175:diagnosis* / Q000378:metabolism
D006063:Chorionic Gonadotropin; D011374:Progesterone
Prognostische Bedeutung der biochemischen und sonographischen Befunde bei Blutungen in der Frühgravidität.