Studies on the evaluation of preservative efficacy--II. The determination of antimicrobial characteristics of benzylalcohol.
A successful kinetic approach to the screening of preservation efficacy of benzylalcohol--a neutral-type preservative--is described. The D-value, activation energy (Ea), temperature coefficient (Q10) and concentration exponent (n) were used as parameters in determining the influence of different factors on the efficacy of benzylalcohol. Factors, such as the pH of the solution, temperature and concentration of the preservative were investigated. The study was carried out using five micro-organisms: Aspergillus niger, Candida albicans, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus.
D001419:Bacteria / Q000187:drug effects*; D019905:Benzyl Alcohol; D001592:Benzyl Alcohols / Q000494:pharmacology*; D001593:Benzyl Compounds / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D003470:Culture Media; D004352:Drug Resistance, Microbial; D005069:Evaluation Studies as Topic; D006863:Hydrogen-Ion Concentration; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D013696:Temperature
D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D003470:Culture Media; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D019905:Benzyl Alcohol