title: Interleukins.
abstract: Interleukins are polypeptides that act on leukocytes and other tissue targets. Interleukin-1, produced by macrophages and other cells, activates lymphocytes and also induces several components of the host's acute-phase response to infection and injury. Interleukin-2, produced by T lymphocytes, is a growth factor for helper, suppressor, and cytotoxic T lymphocytes. By several criteria, interleukins can be considered the hormones that regulate immune and inflammatory responses.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000628:therapy; D000818:Animals; D001424:Bacterial Infections / Q000276:immunology / Q000503:physiopathology; D002478:Cells, Cultured; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000628:therapy; D007167:Immunotherapy; D007249:Inflammation / Q000276:immunology / Q000503:physiopathology; D007375:Interleukin-1 / Q000032:analysis / Q000096:biosynthesis / Q000276:immunology / Q000502:physiology*; D007376:Interleukin-2 / Q000008:administration & dosage / Q000096:biosynthesis / Q000276:immunology / Q000502:physiology*; D051379:Mice; D009374:Neoplasms, Experimental / Q000628:therapy; D013601:T-Lymphocytes / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology
chemical_list: D007375:Interleukin-1; D007376:Interleukin-2