title: Nephrogenic adenoma associated with intravesical bacillus Calmette-Guerin treatment: a report of 2 cases.
abstract: Nephrogenic adenoma, a rare metaplastic change of urothelium, was observed in 2 patients after intravesical bacillus Calmette-Guerin instillation. The lesion has not been reported previously in relation to bacillus Calmette-Guerin immunotherapy. We discuss the pathogenesis of nephrogenic adenoma and suggest that the marked prolonged cystitis induced by bacillus Calmette-Guerin has an etiological role.
mesh_terms: D000236:Adenoma / Q000209:etiology* / Q000473:pathology; D000368:Aged; D001688:Biological Products / Q000008:administration & dosage / Q000009:adverse effects*; D002278:Carcinoma in Situ / Q000150:complications / Q000473:pathology / Q000628:therapy; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000473:pathology / Q000628:therapy; D006801:Humans; D007167:Immunotherapy / Q000009:adverse effects; D007668:Kidney / Q000473:pathology; D008297:Male; D008679:Metaplasia / Q000473:pathology; D009163:Mycobacterium bovis; D013997:Time Factors; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000209:etiology* / Q000473:pathology / Q000628:therapy
chemical_list: D001688:Biological Products