title: A polymorphic variant of the lactate dehydrogenase B subunit in the rat.
abstract: A new electrophoretic variant of the lactate dehydrogenase B subunit was found in the erythrocytes of the COP strain of the rat. The location of the band after the electrophoresis suggested a product of the structural gene for the B subunit. Two alleles that regulated the high amount (Ldh-2a) or the low amount (Ldh-2b) of the B subunit were found and segregated in Mendelian fashion. The activity was regulated by the closely linked (less than 1 cM) regulatory gene Ldr-1.
mesh_terms: D000483:Alleles; D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D005796:Genes; D005809:Genes, Regulator; D008040:Genetic Linkage; D014644:Genetic Variation; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000235:genetics* / Q000302:isolation & purification; D011110:Polymorphism, Genetic; D011487:Protein Conformation; D051381:Rats
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase