Mechanism of known environmental teratogens: drugs and chemicals.
Basic principles of teratology and mechanisms of teratogenesis applicable to human exposures to environmental drugs and chemicals are discussed. The available clinical and experimental animal literature on environmental agents alleged or known to cause human malformations is critically reviewed and summarized.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000016:Abnormalities, Radiation-Induced / Q000209:etiology; D000970:Antineoplastic Agents / Q000009:adverse effects; D000013:Congenital Abnormalities / Q000209:etiology; D000431:Ethanol / Q000009:adverse effects; D005260:Female; D006728:Hormones / Q000009:adverse effects; D006801:Humans; D007231:Infant, Newborn; D007239:Infections / Q000150:complications; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013723:Teratogens
D000970:Antineoplastic Agents; D006728:Hormones; D013723:Teratogens; D000431:Ethanol