title: [Should the injured spleen be preserved?].
abstract: Splenectomy is primarily followed by reduced defence against infection due to encapsulated bacteria, such as pneumococci. Organ preservation, therefore, has been emphasised in the treatment of traumatic rupture of the spleen, especially when it comes to patients in childhood. There are several practicable approaches to orthotopic preservation of the spleen, including conservative treatment of patients for smallest ruptures under stringent clinical control and, even more, fibrin sealing. Growth in accurate knowledge of the segmental structure of the spleen have enabled partial removal of the organ along the poorly vascularised intersegmental regions. Autologous transplantation of splenic pulp into the major omentum should be considered an alternative to splenectomy alone in strictly selected cases of massive splenic rupture.
mesh_terms: D000917:Antibody Formation; D001772:Blood Cell Count; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use; D006801:Humans; D007111:Immunity, Cellular; D011379:Prognosis; D013154:Spleen / Q000637:transplantation; D013156:Splenectomy; D013161:Splenic Rupture / Q000601:surgery*; D013530:Surgical Wound Infection / Q000276:immunology / Q000517:prevention & control; D013536:Suture Techniques; D013917:Thrombin / Q000627:therapeutic use; D014014:Tissue Adhesives / Q000627:therapeutic use
chemical_list: D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin
vernacular_title: Soll die verletzte Milz erhalten werden?