title: Oral administration of ascorbic acid to horses.
abstract: The effects of oral administration of high doses of ascorbic acid on plasma concentrations were investigated in both experimental Thoroughbred horses and those within racing stables. A single oral dose (20 g) did not result in any increase in plasma concentrations. However, daily administration of either 4.5 g or 20 g doses resulted in significant increases in plasma concentrations. Monthly variations in plasma ascorbate concentrations were found in both supplemented (20 g daily) and unsupplemented stables. It is concluded that oral supplementation with ascorbic acid is a satisfactory route to increase plasma and tissue concentrations.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics; D006736:Horses / Q000097:blood*; D007275:Injections, Intravenous; D008297:Male
chemical_list: D001205:Ascorbic Acid