title: Pulmonary epithelial permeability: vascular background effects on whole lung and regional half-time values.
abstract: Pulmonary epithelial permeability was first measured by Jones et al. We have adapted their technique for use with a gamma camera. Both regional half-time values and background correction factors vary from apex to base in the lung. Examination of two methods of background correction show: that inter-segmental half-time comparison is possible without applying individual correction factors to regions. the use of a region of interest with similar vascular supply to that of the lung eliminates the need for a background correction technique that relies upon an intravenous injection of radioisotope. The inter-renal area provides such a vascular area.
mesh_terms: D000328:Adult; D002199:Capillary Permeability; D005260:Female; D006207:Half-Life; D006801:Humans; D008168:Lung / Q000098:blood supply / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D004369:Pentetic Acid; D011652:Pulmonary Circulation; D011877:Radionuclide Imaging; D012907:Smoking; D013667:Technetium; D016284:Technetium Tc 99m Pentetate
chemical_list: D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate