[Effect of ethmozin and Ritmilen on microcirculatory hemostasis in patients with heart rhythm disorders].
Effects of ethmozine and ritmilen were studied in 75 patients with different disorders of cardiac rhythm predominantly proceeding in the form of extrasystole arrhythmia. The drugs were found to exert a distinct antiaggregant action on platelets and erythrocytes which was particularly pronounced at intravenous administration and transiently increased the number of leukocytes and their aggregation. A decrease of platelet aggregation was accompanied by an increase of their number and rejuvenascence of thrombocytogram. A marked antiarrhythmic effect was seen in 66% of patients, in the remaining patients cardiac extracontractions became more rare.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000404:Ajmaline / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000097:blood / Q000188:drug therapy*; D002449:Cell Aggregation / Q000187:drug effects; D004341:Drug Evaluation; D004903:Erythrocyte Aggregation / Q000187:drug effects; D005260:Female; D006487:Hemostasis / Q000187:drug effects*; D006801:Humans; D007962:Leukocytes / Q000187:drug effects; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D016293:Moricizine; D010640:Phenothiazines / Q000627:therapeutic use*; D010974:Platelet Aggregation / Q000187:drug effects
D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines; D000404:Ajmaline; D016293:Moricizine
Vliianie étmozina i ritmilena na mikrotsirkuliatornyĭ gemostaz u bol'nykh s narusheniiami ritma serdtsa.