title: Systemic lupus erythematosus.
abstract: Systemic lupus erythematosus is a multisystem inflammatory disease characterized by autoantibody production. Recent investigations are providing insights into the immunoregulatory disturbances underlying this disease, and are clarifying the approach to diagnosis and treatment.
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex / Q000032:analysis; D000962:Antimalarials / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D002493:Central Nervous System Diseases / Q000276:immunology; D004195:Disease Models, Animal; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007136:Immunoglobulins / Q000096:biosynthesis; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007668:Kidney / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications; D012699:Serology
chemical_list: D000893:Anti-Inflammatory Agents; D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D000962:Antimalarials; D000970:Antineoplastic Agents; D005938:Glucocorticoids; D007136:Immunoglobulins; D007166:Immunosuppressive Agents