Comparative genetic mapping of cellular rel sequences in man, mouse, and the domestic cat.
We used in situ hybridization techniques to assign the human c-rel locus to the centromere-proximal portion of the short arm of chromosome 2 (2cent-2p13). We also determined the chromosomal location of c-rel sequences in the domestic cat and the laboratory mouse by using a human c-rel fragment to screen panels of rodent X cat and hamster X mouse somatic cell hybrid DNAs. The c-rel locus apparently maintains similar syntenic relationships with other known genetic markers in the human and cat, but displays different linkage relationships in the mouse.
D000818:Animals; D002415:Cats; D002874:Chromosome Mapping; D008040:Genetic Linkage; D006801:Humans; D051379:Mice; D009693:Nucleic Acid Hybridization; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D011519:Proto-Oncogenes
D011518:Proto-Oncogene Proteins