title: [Virus-induced antigens in human tumors].
abstract: Solid-phase radioimmunoassay (SPRIA) was used for examinations of human malignant tumors for the presence of retrovirus D-induced antigen and of blood sera from cancer patients for the presence of antibody to this antigen. Various tumor specimens differently reacted to anti-HEp-2 serum, the background values of binding of this serum with normal tissues (liver, lung, spleen) and leukemic cells from leukemia patients being low. The majority of the sera from cancer patients were found to contain antibody to HEp-2 antigen. No correlation was established between high levels of the antigen in tumors and high antibody titres in the blood sera of the same patients.
mesh_terms: D000912:Antibodies, Neoplasm / Q000032:analysis; D000914:Antibodies, Viral / Q000032:analysis; D000957:Antigens, Viral, Tumor / Q000032:analysis*; D002478:Cells, Cultured; D003168:Complement Fixation Tests; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007938:Leukemia / Q000276:immunology; D009369:Neoplasms / Q000276:immunology*; D011863:Radioimmunoassay; D012190:Retroviridae / Q000276:immunology*
chemical_list: D000912:Antibodies, Neoplasm; D000914:Antibodies, Viral; D000957:Antigens, Viral, Tumor
vernacular_title: Virusindutsirovannye antigeny v opukholiakh cheloveka.