title: HLA antigens in Sicilian patients affected by chronic myelogenous leukaemia.
abstract: HLA antigens were investigated in Sicilian patients with chronic myelogenous leukaemia (CML) and in Sicilian healthy controls. The frequency of the HLA-DRw6 antigen was significantly decreased in the group of patients. These results suggest that DRw6 may be a marker for decreased susceptibility to the etiological or pathogenic mechanism(s) which produce CMLs.
mesh_terms: D005787:Gene Frequency; D008040:Genetic Linkage; D005819:Genetic Markers; D006680:HLA Antigens / Q000235:genetics*; D006684:HLA-DR Antigens / Q000235:genetics; D015808:HLA-DR6 Antigen; D006239:Haplotypes; D006801:Humans; D007558:Italy; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics / Q000276:immunology*
chemical_list: D005819:Genetic Markers; D006680:HLA Antigens; D006684:HLA-DR Antigens; D015808:HLA-DR6 Antigen