title: Local muscle flaps in the treatment of chronic osteomyelitis--the introduction of new vasculature.
abstract: Four cases of chronic osteomyelitis successfully managed with local muscle flaps after sequestrectomy are reported. The success of this method in controlling chronic osteomyelitis lies in the introduction of a new vasculature, which provides nutrients, sufficient antibiotics, host defence system and osteoprogenitor cells to the post-sequestrectomy bed. The osteoprogenitor cells are responsible for the incorporation of residual avascular bone into the adjacent living bone by creeping substitution.
mesh_terms: D000328:Adult; D001842:Bone and Bones / Q000098:blood supply / Q000601:surgery*; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D009132:Muscles / Q000601:surgery; D010019:Osteomyelitis / Q000601:surgery*; D012039:Regional Blood Flow; D013524:Surgical Flaps