title: [Specific chromosomal changes (aberrations)--supplementary marker of malignant degeneration in oncomorphologic studies].
abstract: The paper deals with some methods studying chromosome set in tumour cells. The latest data on tumour chromosome aberrations are reported. The latter are subdivided by the authors into non-specific and specific, characteristic only of certain variants of tumour differentiation, and are of diagnostic significance. The authors put forward further tasks of combined oncomorphologic and cytogenetic studies of specific chromosome aberrations as a valuable marker for the diagnosis of malignancy.
mesh_terms: D001402:B-Lymphocytes; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002872:Chromosome Deletion; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics; D007951:Leukemia, Myeloid / Q000235:genetics; D015470:Leukemia, Myeloid, Acute / Q000235:genetics; D008215:Lymphocytes, Null; D008223:Lymphoma / Q000235:genetics; D009369:Neoplasms / Q000235:genetics* / Q000473:pathology; D013601:T-Lymphocytes; D014178:Translocation, Genetic
chemical_list: D005819:Genetic Markers
vernacular_title: Spetsificheskie khromosomnye izmeneniia (aberratsii)--dopolnitel'nyi marker malignizatsii pri onkomorfologicheskikh issledovaniiakh.