[Synthesis of lipids in the thymocytes of irradiated rats].
During the first two hours following whole-body gamma-irradiation of rats with a dose of 7.5 Gy, the content of free cholesterol, phosphatidylcholine and phosphatidylethanolamine in the thymus decreases. Incorporation of 2-14C-acetate into cholesterol and fatty acids of thymus phospholipids in vitro is inhibited. At a dose of 4 Gy, incorporation of 2-14C-acetate into cholesterol and total lipids of thymocytes is activated.
D000818:Animals; D002784:Cholesterol / Q000096:biosynthesis / Q000528:radiation effects; D002788:Cholesterol Esters / Q000096:biosynthesis / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D008055:Lipids / Q000096:biosynthesis* / Q000528:radiation effects; D008297:Male; D010743:Phospholipids / Q000096:biosynthesis / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains; D013601:T-Lymphocytes / Q000378:metabolism / Q000528:radiation effects*; D014916:Whole-Body Irradiation
D002788:Cholesterol Esters; D008055:Lipids; D010743:Phospholipids; D002784:Cholesterol
Sintez lipidov v timotsitakh obluchennykh krys.