Somatomedin-C/insulin-like growth factor-I as a modulator of growth during childhood and adolescence.
Normal growth during childhood and adolescence is a complex process which requires the participation of a number of hormones and growth factors. Sm-C/IGF-I plays a central role in this process, with variations in both its serum concentration and the cellular responsiveness to it being important mechanisms regulating growth.
D000293:Adolescent; D002648:Child; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism / Q000494:pharmacology; D006128:Growth; D006130:Growth Disorders / Q000097:blood; D013006:Growth Hormone / Q000172:deficiency; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000097:blood*; D008297:Male; D013002:Somatomedins / Q000097:blood*; D013963:Thyroid Hormones / Q000172:deficiency
D012739:Gonadal Steroid Hormones; D013002:Somatomedins; D013963:Thyroid Hormones; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone