title: Sister chromatid exchanges in lymphocytes of early cases of nasopharyngeal carcinoma and in 100 healthy subjects.
abstract: Sister chromatid exchange rate was studied in 12 early diagnosed cases of nasopharyngeal carcinoma and in their paired controls. Exchange frequencies were also analyzed in 100 healthy subjects distributed in four regions of Hunan Province and correlated to nationality, age and sex. The incidence of sister chromatid exchange was significantly higher in the cancer patients than in the normal controls. No correlation was found between the frequency of sister chromatid exchange and region, nationality, age or sex.
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000235:genetics*; D002681:China; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000453:epidemiology / Q000235:genetics*; D012854:Sister Chromatid Exchange