The gerbil: a unique model for research on aging.
The Mongolian gerbil (Meriones unguicultatus) is suggested as a model for aging research because of its unique physiological attributes, ease of handling, and because of data previously collected. Factors that demonstrate the gerbils' suitability in fulfulling practical and scientific considerations important in determining a model for aging research are listed. Additionally, several unique physiological attributes of gerbils are described. Based on these attributes and on review of research in gerbils, it is suggested that gerbils can serve as animal models for behavioral and biological processes, and for normative and pathological aspects for aging.
D000302:Adrenal Cortex / Q000502:physiology; D000375:Aging; D000378:Agonistic Behavior; D000818:Animals; D001143:Arousal; D001288:Attention; D001833:Body Temperature Regulation; D001921:Brain / Q000502:physiology; D002561:Cerebrovascular Disorders; D002628:Chemoreceptor Cells / Q000502:physiology; D004195:Disease Models, Animal; D004298:Dopamine / Q000502:physiology; D004327:Drinking Behavior; D004777:Environment; D005247:Feeding Behavior / Q000502:physiology; D005260:Female; D005849:Gerbillinae / Q000502:physiology*; D006309:Hearing / Q000502:physiology; D007668:Kidney / Q000502:physiology; D007858:Learning; D008136:Longevity; D008297:Male; D008954:Models, Biological; D008960:Models, Psychological; D009374:Neoplasms, Experimental; D009747:Nutritional Physiological Phenomena; D014882:Water-Electrolyte Balance
D004298:Dopamine