title: [Laboratory and therapeutic control of oral anticoagulant treatment].
abstract: In our hospital, 199 patients following oral anticoagulant therapy were studied and controlled. They were divided into two groups according to the follow-up period. The first group was treated for 24-40 weeks. The second group was treated for 6-24 weeks. In the first group, 169 (98.3%) of the 172 patients studied maintained therapeutic range INR (2.1-4.8) for a period of 70%-100% of the total observation time, whereas 3 patients (1.7%) did not have a valid therapeutic response. The percentage of subjects within therapeutic range in the second group of 27 patients was decidedly inferior. Five of these patients were not able to achieve the desired results, probably because of a too brief period and undertreatment.
mesh_terms: D015110:4-Hydroxycoumarins / Q000008:administration & dosage / Q000627:therapeutic use*; D000074:Acenocoumarol / Q000008:administration & dosage / Q000627:therapeutic use; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013923:Thromboembolism / Q000517:prevention & control; D014859:Warfarin / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D015110:4-Hydroxycoumarins; D014859:Warfarin; D000074:Acenocoumarol
vernacular_title: Controllo laboratoristico e terapeutico nel trattamento anticoagulante orale.