Tenoxicam in soft-tissue rheumatism.
A randomized double-blind trial with tenoxicam 10 mg/d and 20 mg/d and placebo was carried out for 2 weeks in 90 patients suffering from various extra-articular inflammatory conditions. Statistical analysis revealed significant differences in favour of tenoxicam as regards improvement of all parameters with an intensity which was moderate or severe at baseline, e.g. tenderness, mobility pain, functional limitation. The efficacy of tenoxicam at both dosages was similar (no statistically significant difference). Tenoxicam was well tolerated but some mild adverse reactions were observed in all three treatment groups.
D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005356:Fibromyalgia / Q000188:drug therapy; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009068:Movement; D010146:Pain; D010489:Periarthritis / Q000188:drug therapy; D010894:Piroxicam / Q000031:analogs & derivatives*; D011897:Random Allocation; D012216:Rheumatic Diseases / Q000188:drug therapy*; D052256:Tendinopathy / Q000188:drug therapy; D013716:Tennis Elbow / Q000188:drug therapy; D013843:Thiazines / Q000008:administration & dosage / Q000627:therapeutic use*
D000893:Anti-Inflammatory Agents; D013843:Thiazines; D010894:Piroxicam; C032801:tenoxicam