A review of the use of primates in studying human schistosomiasis.
Rodents, useful models for studies of human schistosomiasis not ethically possible in man, are not satisfactory in every respect. Primates, in many ways better models than rodents, though too expensive for general use, remain invaluable for testing the relevance of rodent findings to man. Higher primates such as chimpanzees are ideal models but, as endangered species, should only be used for critical studies for which lower, nonhuman primates are unsuitable.
D000820:Animal Diseases / Q000276:immunology / Q000473:pathology; D000818:Animals; D004195:Disease Models, Animal; D007167:Immunotherapy; D011323:Primates / Q000276:immunology; D012552:Schistosomiasis / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D012556:Schistosomicides / Q000627:therapeutic use
D012556:Schistosomicides