title: [Isolation and characteristics of Saccharomyces cerevisiae strains with increased sensitivity to detergents].
abstract: The yeast mutants possessing enhanced sensitivity to detergents were obtained after treatment with ethyl methanesulfonate. The whole set of mutants may be divided into three groups, according to sensitivity to: cetylthreemethylammonium chloride detergents and dyes of the ethidium bromide type, detergents, dyes and antibiotics (gramycidin C and actinomycin D). The genetic analysis performed indicated that more than one gene are responsible for sensitivity. On the basis of the test for allelism mutants were distributed into three groups. It was shown that ethidium bromide is far more potent inducer of cytoplasmic petites in detergent-sensitive than in wild-type strains.
mesh_terms: D003902:Detergents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005800:Genes, Fungal; D005819:Genetic Markers; D009154:Mutation; D010641:Phenotype; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics*; D013501:Surface-Active Agents / Q000494:pharmacology*
chemical_list: D003902:Detergents; D005819:Genetic Markers; D013501:Surface-Active Agents
vernacular_title: Poluchenie i kharakteristika shtammov drozhzheĭ Saccharomyces cerevisiae s povyshennoĭ chuvstvitel'nost'iu k detergentam.