title: [Role of vitamins E and C in the development of the malignant process].
abstract: The data on the influence of antioxidant vitamins (E and C) on the growth of induced and transplantable tumours in animals and on the development of cancer process in man as well as on the course of chemo- and radiotherapy are analyzed; a degree of vitamin provision of the tumour-bearing organism is discussed. Special attention is paid to optimal doses of the above mentioned vitamins. The necessity of combined application of antioxidant vitamins in cancer therapy is established.
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001205:Ascorbic Acid / Q000502:physiology* / Q000627:therapeutic use; D001206:Ascorbic Acid Deficiency / Q000378:metabolism; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004357:Drug Synergism; D006801:Humans; D050356:Lipid Metabolism; D008054:Lipid Peroxides / Q000378:metabolism; D051379:Mice; D009369:Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D009602:Nitrosamines / Q000378:metabolism; D010084:Oxidation-Reduction; D010085:Oxidative Phosphorylation; D011817:Rabbits; D051381:Rats; D014018:Tissue Distribution; D014810:Vitamin E / Q000502:physiology* / Q000627:therapeutic use; D014811:Vitamin E Deficiency / Q000378:metabolism
chemical_list: D008054:Lipid Peroxides; D009602:Nitrosamines; D014810:Vitamin E; D001205:Ascorbic Acid
vernacular_title: Rol' vitaminov E i C v razvitii zlokachestvennogo protsessa.