Control of Shigella flexneri in Celebes black macaques (Macaca nigra).
Stool specimens collected systematically from a group of Celebes black macaques (Macaca nigra) with a high incidence of diarrhea were examined microbiologically. Numerous isolates of Shigella flexneri, Campylobacter jejuni and pathogenic Escherichia coli were recovered. Previous parasitology reports had revealed that the majority of the animals had Balantidium coli. Subsequently, the group was treated with trimethoprim-sulfamethoxazole, erythromycin and tetracycline. After treatment, Shigella flexneri was not detected in the stool of any animal for 1 year, and the clinical condition of the group was improved. Reduced recovery rates were obtained with other enteric pathogens.
D000818:Animals; D004338:Drug Combinations / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004405:Dysentery, Bacillary / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D004917:Erythromycin / Q000627:therapeutic use; D008251:Macaca / Q000382:microbiology*; D008992:Monkey Diseases / Q000188:drug therapy* / Q000382:microbiology; D012763:Shigella flexneri / Q000302:isolation & purification; D013420:Sulfamethoxazole / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use; D014295:Trimethoprim / Q000627:therapeutic use; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D004338:Drug Combinations; D004917:Erythromycin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D013752:Tetracycline; D013420:Sulfamethoxazole