Local muscle flaps in the treatment of chronic osteomyelitis--the introduction of new vasculature.
Four cases of chronic osteomyelitis successfully managed with local muscle flaps after sequestrectomy are reported. The success of this method in controlling chronic osteomyelitis lies in the introduction of a new vasculature, which provides nutrients, sufficient antibiotics, host defence system and osteoprogenitor cells to the post-sequestrectomy bed. The osteoprogenitor cells are responsible for the incorporation of residual avascular bone into the adjacent living bone by creeping substitution.
D000328:Adult; D001842:Bone and Bones / Q000098:blood supply / Q000601:surgery*; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D009132:Muscles / Q000601:surgery; D010019:Osteomyelitis / Q000601:surgery*; D012039:Regional Blood Flow; D013524:Surgical Flaps