Early diagnosis of acute postoperative renal transplant rejection by indium-111-labeled platelet scintigraphy.
A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001792:Blood Platelets; D005260:Female; D006084:Graft Rejection; D006801:Humans; D007204:Indium; D007668:Kidney / Q000000981:diagnostic imaging; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D011868:Radioisotopes; D011877:Radionuclide Imaging
D011868:Radioisotopes; D007204:Indium