title: Thyroid carcinoma.
abstract: The issue of appropriate management for thyroid neoplasms remains unsettled. Confusion concerning histology and classification, controversy as to appropriate therapy, the relative indolence of most differentiated thyroid tumors, and various levels of surgical skill have contributed to the prejudice of various approaches to the management of such neoplasms. It appears unlikely that the controversy will be resolved in the immediate future. If total thyroidectomy can be performed by a skilled surgeon with minimal complications, this approach seems theoretically justifiable for the management of most differentiated tumors, facilitating follow-up postoperatively. Conclusive evidence for improved survival with this rationale is insufficient.
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery; D000328:Adult; D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D002291:Carcinoma, Papillary / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013954:Thyroglobulin / Q000097:blood; D013963:Thyroid Hormones / Q000627:therapeutic use; D013964:Thyroid Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D013965:Thyroidectomy; D013972:Thyrotropin / Q000037:antagonists & inhibitors
chemical_list: D007457:Iodine Radioisotopes; D013963:Thyroid Hormones; D013972:Thyrotropin; D013954:Thyroglobulin