[Predicting the effectiveness of nitrosorbide with regard to increasing tolerance to physical loads].
A study of the indices of spiroergometry, tetrapolar rheography, echocardiography at rest and during bicycle ergometry in 50 patients after myocardial infarction prior to and after the use of nitrosorbide showed that the use of this drug to raise exercise tolerance was recommended to patients after myocardial infarction with a considerable enlargement of the left ventricle. The invariability of heart rate after taking the drug at rest served as a prognostic criterion for the use of nitrosorbide to raise exercise tolerance. Increased cardiac rhythm at rest by 11% and upwards after the use of the drug was a sign of its inefficacy for the above purpose.
D000328:Adult; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000188:drug therapy*; D005080:Exercise Test; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D011379:Prognosis; D014665:Vasodilator Agents / Q000627:therapeutic use*
D014665:Vasodilator Agents; D007548:Isosorbide Dinitrate
K prognozirovaniiu effektivnosti deĭstviia nitrosorbida v otnoshenii povysheniia perenosimosti fizicheskikh nagruzok.