[Diabetic microangiopathy and oxygen transport disorder (a review of the literature and the authors' own data)].
Proceeding from biochemical and instrumental investigations on a vast material (560 patients with various forms of diabetes mellitus) and literature data the authors propose a new concept of occurrence and progression of diabetic microangiopathies. Importance is attached to tissue hypoxia related to an entire complex of hormonal-metabolic changes resulting in a disturbed supply of oxygen to the tissues.
D001692:Biological Transport; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism; D003925:Diabetic Angiopathies / Q000209:etiology / Q000378:metabolism*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D006943:Hyperglycemia / Q000378:metabolism; D000860:Hypoxia / Q000378:metabolism; D050356:Lipid Metabolism; D008297:Male; D008833:Microcirculation / Q000378:metabolism; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption; D010313:Partial Pressure
D006442:Glycated Hemoglobin; D010100:Oxygen
Diabeticheskaia mikroangiopatiia i narushenie transporta kisloroda (obzor literatury i sobstvennye dannye).