title: Influence of naloxone on relief of acute oro-facial pain by transcutaneous electrical nerve stimulation (TENS) or vibration.
abstract: Twenty-eight patients suffering acute pain following operative removal of impacted third molars took part in the present study. In 20 patients who reported pain reduction exceeding 25% of the initial pain intensity during vibratory stimulation (100 Hz) or TENS (2 or 100 Hz), only 1 patient (given 2 Hz TENS) reported pain increase after injection of 0.8 mg naloxone (i.v.). In 8 patients, not treated with afferent stimulation, 2 experienced increase in pain intensity after naloxone injection. The results show that pain relief using TENS or vibration is not influenced by naloxone.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D004599:Electric Stimulation Therapy; D005157:Facial Pain / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000209:etiology; D009270:Naloxone / Q000008:administration & dosage*; D010149:Postoperative Pain / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D014095:Tooth, Impacted / Q000601:surgery; D004561:Transcutaneous Electric Nerve Stimulation; D014732:Vibration / Q000627:therapeutic use*
chemical_list: D009270:Naloxone