Pharmacopsychological effects of flunarizine in geriatric patients with light brainorganic psychosyndrome. Preliminary communication.
The effects of the cerebral calcium antagonist flunarizine in 50 geriatric patients with light brainorganic psychosyndrome were determined in the course of a 12 weeks' placebo-controlled pharmacopsychological double-blind study. Factor analysis on the basis of 19 individual psychological tests served as multivariate evaluation model. Advantages of flunarizine became evident in factors 1 (contentedness), 3 (alertness) and 4 (good memory/sound sleep). The increased performance (factor 2) in both groups may well be due to a training effect and would, therefore, be artificial.
D000368:Aged; D000369:Aged, 80 and over; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005163:Factor Analysis, Statistical; D005260:Female; D005444:Flunarizine / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy*
D005444:Flunarizine