title: The joint effect of overweight and familial predisposing factors on the occurrence of hypertension in the industrial population. The Pavia study.
abstract: The main purpose of the study was to assess the effect of overweight and predisposing familial factors on the occurrence of hypertension in the industrial population. The data were based on large sample (1523 males and 438 females) of workers employed in the petrochemical industry. The results of the cross-sectional study show that the prevalence of hypertension and borderline hypertension was significantly related to age, obesity and cardiovascular familial history. The effect of obesity alone was slightly stronger than the impact of family history on the occurrence of hypertension among men, but inverse relationship has been found in women Relative excess risk due to interaction between obesity and heredity was 0.60 in males and 2.75 in females. Total proportion of hypertension cases attributable to overweight and heredity together or singly in men was 71.5% and in women 79.4%. That part of the disease attributable to interaction between both factors was 17.1% in men and 56.7% in women.
mesh_terms: D000328:Adult; D000367:Age Factors; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000209:etiology / Q000235:genetics; D007558:Italy; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D012044:Regression Analysis; D012307:Risk Factors; D012737:Sex Factors