title: [Ofloxacin versus pipemidic acid and co-trimoxazole].
abstract: In a study comprising 116 patients at a hospital for general care, ofloxacin was tested in various doses and at various time intervals against pipemidic acid (for infections of the lower urinary tract) and co-trimoxazole forte (for infections of the upper urinary tract). Ofloxacin proved superior to the other drugs both clinically and, particularly, bacteriologically. Of 77 patients treated with ofloxacin, only one complained of diarrhoea as a side-effect of the drug.
mesh_terms: D000328:Adult; D000892:Anti-Infective Agents, Urinary / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004338:Drug Combinations / Q000627:therapeutic use; D006801:Humans; D009539:Nicotinic Acids / Q000627:therapeutic use*; D015242:Ofloxacin; D010078:Oxazines / Q000627:therapeutic use*; D010876:Pipemidic Acid / Q000627:therapeutic use*; D011897:Random Allocation; D013420:Sulfamethoxazole / Q000627:therapeutic use*; D014295:Trimethoprim / Q000627:therapeutic use*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D000892:Anti-Infective Agents, Urinary; D004338:Drug Combinations; D009539:Nicotinic Acids; D010078:Oxazines; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D015242:Ofloxacin; D014295:Trimethoprim; D013420:Sulfamethoxazole; D010876:Pipemidic Acid
vernacular_title: Ofloxacin versus Pipemidsäure und Co-trimoxazol.