title: Angioneurotic edema, agranulocytosis, and fatal septicemia following captopril therapy.
abstract: Captopril, an angiotensin converting enzyme inhibitor used in the treatment of hypertension, has been associated with hematologic as well as dermatologic side effects. Two patients with captopril-induced angioneurotic edema, one of whom had fatal granulocytopenia and overwhelming polymicrobial sepsis, are presented.
mesh_terms: D000380:Agranulocytosis / Q000139:chemically induced* / Q000150:complications; D000799:Angioedema / Q000139:chemically induced* / Q000150:complications; D002216:Captopril / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018805:Sepsis / Q000150:complications*
chemical_list: D002216:Captopril