[Effect of the combined use of chemical radioprotectors and inhibitors of prostaglandin biosynthesis on the postradiation recovery of hemopoiesis in mice].
In experiments on mice it was shown that chemical radioprotective agents and inhibitors of prostaglandins, which were administered in a combination after irradiation to promote the haemopoiesis recovery, exerted a pronounced hemo-stimulating effect exceeding that produced by each of the agents applied separately and increasing the survival of mice.
D008735:5-Methoxytryptamine / Q000627:therapeutic use; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003037:Cobalt Radioisotopes; D003538:Cystamine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005720:Gamma Rays; D006410:Hematopoiesis / Q000187:drug effects*; D007213:Indomethacin / Q000627:therapeutic use; D008297:Male; D051379:Mice; D011453:Prostaglandins / Q000096:biosynthesis*; D011833:Radiation Injuries, Experimental / Q000188:drug therapy / Q000503:physiopathology*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D014916:Whole-Body Irradiation
D000893:Anti-Inflammatory Agents; D003037:Cobalt Radioisotopes; D011453:Prostaglandins; D011837:Radiation-Protective Agents; D008735:5-Methoxytryptamine; D003538:Cystamine; D007213:Indomethacin
Vliianie kombinirovannogo primeneniia khimicheskikh radioprotektorov s ingibitorami biosinteza prostaglandinov na postluchevoe vosstanovlenie gemopoéza u mysheĭ.