Dissemination of the tetM tetracycline resistance determinant to Ureaplasma urealyticum.
Ureaplasma urealyticum is an organism considered susceptible to tetracycline. Ten tetracycline-resistant (Tcr) clinical isolates and Tcr serotype 9 were examined. All contained DNA sequences homologous to the streptococcal determinant tetM. They differed from each other on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Southern blots, and immunoblots and appeared to represent different strains.
D004269:DNA, Bacterial / Q000032:analysis; D004352:Drug Resistance, Microbial; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007163:Immunosorbent Techniques; D009693:Nucleic Acid Hybridization; D011815:R Factors; D012689:Sequence Homology, Nucleic Acid; D013292:Streptococcus agalactiae / Q000187:drug effects / Q000235:genetics; D013752:Tetracycline / Q000494:pharmacology*; D014509:Ureaplasma / Q000187:drug effects / Q000235:genetics*
D004269:DNA, Bacterial; D013752:Tetracycline