Immunocytochemical localization of aspartate aminotransferase and glutaminase immunoreactivities in the cerebellum.
The distributions of glutaminase and aspartate aminotransferase were studied immunocytochemically in the cerebellum of the guinea pig and the rat. In the granule cell layer, both antibodies gave a similar staining pattern. Granule cell bodies were labeled, but staining was also found to lie outside the cell body, associated with what appear to be synaptic processes. In the molecular and Purkinje cell layers, aspartate aminotransferase was concentrated in stellate and basket cell bodies and in terminal baskets beneath Purkinje cells. Glutaminase, however, was not concentrated in these structures.
D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D002531:Cerebellum / Q000201:enzymology*; D005260:Female; D005972:Glutaminase / Q000378:metabolism*; D006168:Guinea Pigs; D007124:Immunoenzyme Techniques; D008297:Male; D051381:Rats
D001219:Aspartate Aminotransferases; D005972:Glutaminase