title: Acute cholangitis in Singapore.
abstract: 115 cases of acute calculous cholangitis were analysed for their presentations, treatment and complications. There were slightly more Chinese males than females (1.4:1) and the mean age was 62 years old. Though pain was the commonest symptom (95.7%), only 35.7% of patients had complete Charcot's triad. 21.7% presented in septicaemic shock. E. Coli and Klebsiella were the commonest organisms isolated. All patients had cholecystectomy and exploration of common bile ducts. Twenty patients had additional choledochontrostomy performed. 50.4% of patients developed complications and the overall mortality was 16.5%. Patients over 60 presented in shock carried a significantly higher mortality (40%).
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002761:Cholangitis / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology / Q000601:surgery; D002769:Cholelithiasis / Q000150:complications; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007709:Klebsiella / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012769:Shock / Q000150:complications; D012846:Singapore