Measurement of the fetal urine production rate using real-time ultrasound in fetuses with bilateral hydronephrosis.
The fetal urine production rate (FUPR) in 147 normal fetuses after 27 weeks of gestation and 5 with bilateral hydronephrosis was measured using real-time ultrasound. Later, the correlation between FUPR and renal function was evaluated postnatally. In the normal fetuses, FUPR (mean +/- 2 SD) increased gradually from 1.9 +/- 1.6 at 27-28 weeks of gestation to 7.5 +/- 4.5 ml/10 min at 37-38 weeks of gestation. In the 5 cases with bilateral hydronephrosis, FUPR was within normal ranges and increased with advances in gestation. Intrauterine intervention was not performed in any of the cases, and, at present, renal insufficiency is nil.
D005260:Female; D005315:Fetal Diseases / Q000503:physiopathology / Q000652:urine*; D005333:Fetus / Q000502:physiology*; D005865:Gestational Age; D006801:Humans; D006869:Hydronephrosis / Q000151:congenital / Q000503:physiopathology / Q000652:urine*; D007231:Infant, Newborn; D011247:Pregnancy; D014465:Ultrasonics