[Comparative evaluation of bovine serum albumin and ovalbumin proteolysis in the small intestine of rat pups on artificial feeding].
Relationship between the type of protein digestion in gastrointestinal tract and coefficient of protein efficiency (CPE) was studied after artificial feeding of 15-21 days-old rats using milk substitutes. Distinctly low level of CPE was observed after rapid transfer of blood serum albumin (BSA) along the gastrointestinal tract accompanied by the protein intensive proteolysis. On the other hand, a considerable retardation of ovalbumin in intestine and the low rate of its proteolysis resulted in high efficiency of the protein consumption. Thus, a long-term transfer of protein in gastrointestinal tract is of paramount importance for its effective consumption at the early neonatal period. Therefore ovalbumin may be a better component in the protein complex of the milk substitutes as compared with BSA. Caseins, which are coagulated in stomach simultaneously with formation of peptides, affecting actively the functions of gastrointestinal tract, appear to maintain the most suitable for neonates rate of digestion and absorption of proteins, responsible for highly effective consumption of a protein mixture including casein. The most intensive digestion and absorption of the milk protein substitutes occurred in the middle and distal sections of small intestine. Cavital digestion of proteins was shown to be incomplete in spite of its relatively high efficiency.
D000818:Animals; D000833:Animals, Suckling; D002850:Chromatography, Gel; D005526:Food, Formulated / Q000032:analysis*; D006868:Hydrolysis; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism*; D008892:Milk / Q000378:metabolism*; D008894:Milk Proteins / Q000378:metabolism; D010047:Ovalbumin / Q000032:analysis*; D010447:Peptide Hydrolases / Q000378:metabolism; D051381:Rats; D012710:Serum Albumin, Bovine / Q000032:analysis*
D008894:Milk Proteins; D012710:Serum Albumin, Bovine; D010047:Ovalbumin; D010447:Peptide Hydrolases
Sravnitel'naia otsenka proteoliza bych'ego syvorotochnogo al'bumina i oval'bumina v tonkom kishechnike krysiat pri iskusstvennom vskarmlivanii.