IgE in postsecretory ameloblasts suggesting a hypersensitivity reaction at tooth eruption.
The clinical symptoms associated with the eruption of primary teeth resemble a mild hypersensitivity reaction. Light microscopic examination showed that IgE accumulated in postsecretory ameloblasts. The formation of IgE was elicited by enamel matrix proteins, which are chemotactic for mast cells.
D000565:Ameloblasts / Q000276:immunology*; D000818:Animals; D003743:Dental Enamel / Q000276:immunology; D003746:Dental Enamel Proteins / Q000276:immunology; D006651:Histocytochemistry; D006967:Hypersensitivity / Q000276:immunology*; D007124:Immunoenzyme Techniques; D007073:Immunoglobulin E / Q000032:analysis*; D007180:Incisor / Q000276:immunology; D051379:Mice; D008815:Mice, Inbred Strains; D008963:Molar / Q000276:immunology; D014078:Tooth Eruption
D003746:Dental Enamel Proteins; D007073:Immunoglobulin E