title: [Genetic analysis of mitochondrial rho-mutability in Saccharomyces. I. Polygenic determination of spontaneous rho-mutability: gene-modifiers and srm mutation].
abstract: The phenotypic trait "starry colony" in Saccharomyces is associated with a high spontaneous rho- petite mutability. Genetic analysis of this trait has shown the high rho- mutability to be caused by several modifying genes present together in the cell genome. Every single modifying gene only produces a relatively small enhancement in the rho- mutability. Mutations in four nuclear srm (spontaneous rho- mutability) loci were isolated after mutagenic treatment of highly rho- mutable haploid cells. In contrast to the modifying genes, each of these mutations has a pronounced effect on the spontaneous rho- mutability, causing significant decrease in it.
mesh_terms: D004271:DNA, Fungal / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D005800:Genes, Fungal; D005809:Genes, Regulator; D008040:Genetic Linkage; D005819:Genetic Markers; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D004272:DNA, Mitochondrial; D005819:Genetic Markers
vernacular_title: Geneticheskiĭ analiz mitokhondrial'noĭ rho-mutabil'nosti u drozhzheĭ sakharomitsetov. Soobshchenie I. Poligennaia determinatsiia spontannoĭ rho-mutabil'nosti: geny-modifikatory i mutatsii srm.