[Therapy of pemphigus and pemphigoid].
Severe cases of pemphigus vulgaris should be treated with prednisone in high dosage (180-360 mg daily). In milder cases, we prefer the combined therapy with prednisone 40 mg every other day and an immunosuppressive drug, i.e. azathioprin, cyclophosphamide, or methotrexate. For treatment of bullous pemphigoid, the combined therapy is usually sufficient.
D001379:Azathioprine / Q000009:adverse effects / Q000627:therapeutic use; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use; D010391:Pemphigoid, Bullous / Q000188:drug therapy*; D010392:Pemphigus / Q000188:drug therapy*; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy*
D003520:Cyclophosphamide; D001379:Azathioprine; D011241:Prednisone; D008727:Methotrexate
Die Therapie des Pemphigus und Pemphigoid.