title: An overview of serological tests currently available for laboratory diagnosis of parasitic infections.
abstract: Current methods and commercial test systems for the diagnosis of parasitic infections in both animals and humans are reviewed. Lists of test kits and their manufacturers are provided along with ordering information: the only commercially available test kits are for the diagnosis of toxoplasmosis in humans or animals and dirofilariasis (heartworm) in dogs. A partial list of diagnostic laboratories and the parasite tests they perform is also provided. Complete lists of diagnostic tests that could be obtained in the private sector are not available but would be useful. Two microfluorometric solid-phase assay systems are reviewed, and adaptations to custom assays for several kinds of parasites are briefly described. User problems in performing tests and interpreting results are stressed with emphasis placed on diagnosis of dirofilariasis in dogs. False-positive serology in dogs without heartworms and negative antibody responses in micro-filariae-positive animals are discussed with respect to proper interpretation of results.
mesh_terms: D000712:Anaplasmosis / Q000175:diagnosis; D000818:Animals; D000947:Antigens, Helminth / Q000276:immunology*; D000953:Antigens, Protozoan / Q000276:immunology*; D002415:Cats; D002417:Cattle; D003168:Complement Fixation Tests; D003592:Cytophotometry; D004184:Dirofilariasis / Q000175:diagnosis; D004285:Dogs; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D006041:Goats; D006736:Horses; D006801:Humans; D010272:Parasitic Diseases / Q000175:diagnosis* / Q000276:immunology; D010273:Parasitic Diseases, Animal; D011863:Radioimmunoassay; D011933:Reagent Kits, Diagnostic / Q000592:standards / Q000662:veterinary; D012698:Serologic Tests; D012756:Sheep; D014123:Toxoplasmosis / Q000175:diagnosis; D014124:Toxoplasmosis, Animal / Q000175:diagnosis
chemical_list: D000947:Antigens, Helminth; D000953:Antigens, Protozoan; D011933:Reagent Kits, Diagnostic