title: [Biochemical mechanisms of the effect of low molecular weight organochlorine aliphatic compounds on humans and animals (review)].
abstract: Data on the effects of 1,1,1-trichlorethane and tetrachlorethylene on human and animal organisms are reviewed. These compounds are used in industry and in homeservice. The review deals with some aspects of the action of these organic solvents at the subcellular level.
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D000818:Animals; D001944:Breath Tests; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism / Q000494:pharmacology / Q000506:poisoning*; D008297:Male; D008452:Maximum Allowable Concentration; D009153:Mutagens; D009784:Occupational Diseases / Q000139:chemically induced; D010101:Oxygen Consumption / Q000187:drug effects; D012125:Respiratory Center / Q000187:drug effects; D012997:Solvents; D013329:Structure-Activity Relationship; D014240:Trichloroethanes / Q000378:metabolism / Q000494:pharmacology / Q000506:poisoning; D014241:Trichloroethylene / Q000378:metabolism / Q000494:pharmacology / Q000506:poisoning
chemical_list: D006843:Hydrocarbons, Chlorinated; D009153:Mutagens; D012997:Solvents; D014240:Trichloroethanes; D014241:Trichloroethylene
vernacular_title: Biokhimicheskie mekhanizmy deĭstviia nizkomolekuliarnykh khlororganicheskikh alifaticheskikh soedineniĭ na organizm cheloveka i zhivotnykh (obzor).