Nodular fibrous proliferation (fibrous pseudotumour) of the tunica vaginalis testis. A light, electron microscopic and immunocytochemical study of a case and review of the literature.
A case of nodular fibrous proliferation of the tunica vaginalis testis occurring in a 25-year-old male is described. Electron microscopy and immunocytochemical analysis confirm a fibroblastic origin. The histogenesis of the lesion is considered in the light of the findings and a review of the literature. It is concluded that the lesions known variously as 'fibrous pseudotumour' and 'reactive periorchitis' represent a fibroblastic overgrowth of the genito-urinary tract in response to trauma or infection. Nodular or diffuse fibrous proliferation of the testicular tunica vaginalis is suggested as a unifying terminology for this group of lesions.
D000328:Adult; D000951:Antigens, Neoplasm / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D013736:Testicular Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D013737:Testis / Q000473:pathology* / Q000648:ultrastructure
D000951:Antigens, Neoplasm