title: History of exercise-induced asthma.
abstract: Strenuous exercise prolonged for several minutes can cause airway obstruction in asthmatic subjects. Initial obstruction becomes most extreme 5-10 min after the completion of exercise and usually remits within a few minutes but may recur 3-6 h later. The response to exercise depends upon the type of exercise. Swimming is less likely to cause exercise-induced asthma than running. Recent exercise or pretreatment with a bronchodilator or cromolyn can inhibit exercise-induced asthma. Nasal breathing or inhalation of warm, fully humidified air during exercise can minimize exercise-induced asthma. Local changes in osmolarity or cooling of mast cells probably causes release of mediators that cause airway obstruction.
mesh_terms: D001249:Asthma / Q000209:etiology*; D001250:Asthma, Exercise-Induced / Q000188:drug therapy / Q000209:etiology* / Q000266:history / Q000503:physiopathology; D001634:Bibliographies as Topic; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002648:Child; D049670:History, 17th Century; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049690:History, Ancient; D006801:Humans; D012123:Pulmonary Ventilation; D013997:Time Factors
chemical_list: D001993:Bronchodilator Agents