The induction of tolerance by cyclosporine-G in experimental autoimmune uveitis in the Lewis rat.
Cyclosporine-G inhibits retinal S-antigen-induced experimental autoimmune uveitis in a manner similar to Cyclosporine-A (CsA). In sufficiently high doses it induces a state of tolerance in the animal which persists after cessation of therapy.
D000818:Animals; D000941:Antigens / Q000276:immunology; D019393:Arrestin; D001327:Autoimmune Diseases / Q000276:immunology* / Q000473:pathology; D002455:Cell Division; D016572:Cyclosporine; D003524:Cyclosporins / Q000494:pharmacology*; D005136:Eye Proteins / Q000276:immunology; D005260:Female; D007107:Immune System / Q000187:drug effects*; D007108:Immune Tolerance; D008198:Lymph Nodes / Q000473:pathology; D051381:Rats; D011917:Rats, Inbred Lew; D014605:Uveitis / Q000276:immunology* / Q000473:pathology
D000941:Antigens; D019393:Arrestin; D003524:Cyclosporins; D005136:Eye Proteins; C045571:cyclosporin G; D016572:Cyclosporine