title: Endobronchial management of lung cancer.
abstract: Bronchoscopic phototherapy is available now for 2 distinct categories of tracheobronchial cancer: roentgenographically occult superficial squamous cell carcinoma and advanced malignancy causing significant airway obstruction. Laboratory and clinical experience show that the photodynamic effect of hematoporphyrin derivative phototherapy (HpD-PT) may be useful for treating superficial cancers that penetrate less than 5 mm into bronchial mucosa. The larger, obstructing cancers are better managed by high-power laser sources, such as the YAG laser, which are effective by hyperthermal photocoagulation, thermal necrosis, and tissue vaporization.
mesh_terms: D000402:Airway Obstruction / Q000209:etiology; D001984:Bronchial Neoplasms / Q000601:surgery / Q000628:therapy; D001999:Bronchoscopy; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D005336:Fiber Optic Technology; D006801:Humans; D053685:Laser Therapy; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D010789:Phototherapy / Q000379:methods; D014134:Tracheal Neoplasms / Q000628:therapy