Lack of immunoglobulin A1 protease production by Branhamella catarrhalis.
Clinical isolates of Branhamella catarrhalis from the sputum of 20 patients with acute bronchopulmonary infection were examined for synthesis of immunoglobulin A1 protease by immunoelectrophoresis. Ten strains produced beta-lactamase, and 10 were beta-lactamase negative. None of the strains demonstrated immunoglobulin A1 protease activity despite the fact that three different culture media were used.
D006801:Humans; D009346:Neisseriaceae / Q000201:enzymology* / Q000276:immunology; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D012141:Respiratory Tract Infections / Q000382:microbiology; D012697:Serine Endopeptidases
D010447:Peptide Hydrolases; D012697:Serine Endopeptidases; C021433:IgA-specific serine endopeptidase