[Contact dermatitis caused by Septopal].
A man affected of a femur osteomyelitis was treated with Septopal (Merck) and presented an allergic contact dermatitis on the left thigh, thorax, abdomen with bilateral oedema of eyelids and generalized pruritus. The cause was a co-polymer of methyl-methacrylate-methacrylate of the material of the small balls of Septopal, which liberates gentamycin contained inside through little pores.
D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D005593:Fracture Fixation, Internal / Q000009:adverse effects; D005839:Gentamicins / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008768:Methylmethacrylates / Q000009:adverse effects*; D010019:Osteomyelitis / Q000150:complications / Q000188:drug therapy; D011183:Postoperative Complications / Q000139:chemically induced*; D012882:Skin Tests; D013530:Surgical Wound Infection / Q000188:drug therapy
D005839:Gentamicins; D008768:Methylmethacrylates; C030159:gentamicin-polymethylmethacrylate bead
Dermatitis de contacto por Septopal.