title: [Effect of interferon type I on the in vivo persistence of Salmonella typhimurium].
abstract: The influence of type I interferon on the persistence of S. typhimurium in the body of mice has been studied. The injection of the preparation of interferon has been shown to be conductive to the survival of the animals and to reduce the time of Salmonella persistence in the body. The injection of interferon enhances the phagocytic activity of macrophages in the peritoneal exudate of mice.
mesh_terms: D000818:Animals; D004353:Drug Evaluation, Preclinical; D007370:Interferon Type I / Q000627:therapeutic use*; D008264:Macrophages / Q000187:drug effects / Q000276:immunology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010587:Phagocytosis / Q000187:drug effects; D012481:Salmonella Infections, Animal / Q000276:immunology / Q000382:microbiology / Q000628:therapy*; D012486:Salmonella typhimurium / Q000302:isolation & purification; D013997:Time Factors
chemical_list: D007370:Interferon Type I
vernacular_title: Vliianie interferona tipa I na persistentsiiu Salmonella typhimurium in vivo.