Effects of acetylpromazine on the hemodynamics of the equine metatarsal artery, as determined by two-dimensional real-time and pulsed Doppler ultrasonography.
Heart rate, blood velocity, volumetric blood flow, and arterial diameter for 10 horses given acetylpromazine were determined from measurements of the dorsal metatarsal artery 3 (the great metatarsal artery), using 2-dimensional real-time and gated pulsed Doppler ultrasonography. Acetylpromazine induced significant increases in arterial diameter (P less than 0.01) and volumetric flow rate (P less than 0.05)--all compatible with adrenergic blockade. There was a trend indicating that there was increased blood velocity. Heart rate was unchanged.
D000075:Acepromazine / Q000494:pharmacology*; D000818:Animals; D006439:Hemodynamics / Q000187:drug effects; D006614:Hindlimb / Q000098:blood supply*; D006736:Horses / Q000502:physiology*; D008684:Metatarsus / Q000098:blood supply*; D014463:Ultrasonography / Q000662:veterinary*
D000075:Acepromazine