title: Transfer of resistance to syphilitic infection from maternal to newborn guinea pigs.
abstract: Partial protection against cutaneous syphilis and dissemination of treponemes to the regional lymph nodes was achievable in Treponema pallidum-infected neonatal strain 2 guinea pigs having syphilis-immune mothers. This evidence for enhanced resistance was associated with the natural transfer of antitreponemal, maternally derived immunoglobulins before parturition.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000276:immunology*; D000907:Antibodies, Bacterial / Q000032:analysis; D005260:Female; D006168:Guinea Pigs; D007116:Immunization, Passive; D008431:Maternal-Fetal Exchange; D008892:Milk / Q000276:immunology; D011247:Pregnancy; D013587:Syphilis / Q000276:immunology*; D014210:Treponema pallidum / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial