[Autoantibodies in vitiligo. Clinical significance].
The occurrence of circulating autoantibodies was determined by indirect immunofluorescence in patients with vitiligo. In addition we determined the existence of anti-melanocytic antibodies by an immunofluorescence complement fixation technique, immunoglobulins in achromic and perilesional skin, complement (C3 and C4) and immunoglobulins in serum by immunoelectrophoresis. The results only indicate that a significant occurrence of circulating autoantibodies exists, especially antithyroid autoantibodies, which, moreover, are related to the vitiligos which affect important areas of the cutaneous surface (generalized vitiligo).
D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000276:immunology* / Q000473:pathology; D003165:Complement System Proteins / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006801:Humans; D008544:Melanocytes / Q000276:immunology; D012867:Skin / Q000032:analysis; D013961:Thyroid Gland / Q000276:immunology; D014820:Vitiligo / Q000276:immunology* / Q000473:pathology
D001323:Autoantibodies; D003165:Complement System Proteins
Autoanticuerpos en vitíligo. Significado clínico.