title: Therapy of primary cutaneous melanoma.
abstract: The essential tenets of early recognition, biopsy, and appropriate surgical treatment of melanoma are reviewed. The controversies of elective regional lymph node dissection and isolated limb perfusion are discussed, as well as the newer modalities of immunotherapy.
mesh_terms: D001706:Biopsy; D010478:Chemotherapy, Cancer, Regional Perfusion; D006801:Humans; D007167:Immunotherapy; D008197:Lymph Node Excision; D008545:Melanoma / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*