title: [Basic characteristics of the process of Candida adhesion to human epitheliocytes].
abstract: The adhesion of fungi belonging to the genus Candida to the epithelial cells of the mouth cavity reached its maximum at pH 6.2-7.0. The process of adhesion had similar dynamics at temperatures of 37 degrees, 28 degrees and 25 degrees C, but the adhesive activity decreased 2 times when temperature dropped from 37 degrees to 25 degrees and 4 times when temperature dropped to 4 degrees C. The introduction of the ions Ca2+ (1 and 10 mM) and Mg2+ (10 mM) led to the increase of adhesion by 80, 100 and 24% respectively. The heating of the fungal cells at 100 degrees C (for 1 hour) and at 63 degrees C (for 2 hours) decreased adhesion to 8 and 24% respectively, and treatment with formaldehyde (for 24 hours) decreased adhesion to 70% of that observed in experiments with live Candida cells.
mesh_terms: D000268:Adhesiveness; D000328:Adult; D002176:Candida albicans / Q000187:drug effects / Q000472:pathogenicity*; D004847:Epithelial Cells; D004848:Epithelium / Q000382:microbiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D009061:Mouth Mucosa / Q000166:cytology / Q000382:microbiology*; D013696:Temperature; D013997:Time Factors
vernacular_title: Osnovnye kharakteristiki protsessa adgezii gribov Candida k épiteliotsitam cheloveka.