Evaluation of three formulations of fenbendazole (10% suspension, 0.5% pellets, and 20% premix) against nematode infections in cattle.
Anthelmintic efficacies of 3 formulations of fenbendazole were evaluated in cattle naturally parasitized with nematodes: a 10% oral suspension, 0.5% pellets as a top dressing on feed, and a 20% premix. All formulations of fenbendazole were greater than 99% effective in removing adults of Haemonchus contortus, Ostertagia spp, Cooperia spp, and Oesophagostomum radiatum. Fenbendazole was greater than 96% effective in removing adults of Strongyloides papillosus and greater than 85% effective in the removal of Trichuris sp. Fenbendazole was greater than 96% effective against immature nematodes, which were thought to be primarily Cooperia spp. Adverse reactions were not observed in calves treated with the 3 formulations of fenbendazole.
D000818:Animals; D001562:Benzimidazoles / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004304:Dosage Forms; D005260:Female; D005273:Fenbendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009348:Nematoda / Q000302:isolation & purification; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*
D001562:Benzimidazoles; D004304:Dosage Forms; D005273:Fenbendazole