title: Role of arginine vasopressin in regulation of systemic arterial pressure.
abstract: Arginine vasopressin (AVP) not only influences renal water metabolism but also has profound cardiovascular effects. Physiologic levels of the hormone produce a pressor response in the basal state when vasoregulatory reflex mechanisms are interrupted. During hypovolemia, vasopressin affects systemic blood pressure independent of the renin-angiotensin system and efferent sympathetic pathways. Many studies implicate AVP in the pathogenesis of hypertension, but the actual mechanism and relative importance of vasopressin's role remain a matter of intense investigation.
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000097:blood / Q000494:pharmacology / Q000502:physiology*; D001794:Blood Pressure / Q000187:drug effects; D001810:Blood Volume; D004285:Dogs; D006439:Hemodynamics; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D006978:Hypertension, Renovascular / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D011311:Pressoreceptors / Q000502:physiology; D051381:Rats; D011910:Rats, Brattleboro; D011919:Rats, Inbred Strains; D012084:Renin-Angiotensin System
chemical_list: D001127:Arginine Vasopressin