[Mechanism of the antibacterial action of monocarboxycellulose and other ion-exchange derivatives of cellulose].
The mechanism of the antibacterial effect of monocarboxyl cellulose (MCC) and other ion exchange derivatives of cellulose was studied. It was shown that MCC, cellulose phosphate and aminocellulose had a pronounced antibacterial effect due to the presence of the ionogenic group H+ or OH- in the initial drugs. A certain role in this process was played by sorption. The level of the antibacterial activity of MCC depended on the number of the carboxylic groups. MCC is promising as a dressing material.
D001458:Bandages; D002482:Cellulose / Q000031:analogs & derivatives* / Q000494:pharmacology; D002483:Cellulose, Oxidized / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D007475:Ion Exchange Resins / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship
D002483:Cellulose, Oxidized; D007475:Ion Exchange Resins; D002482:Cellulose; C008881:phosphocellulose; C585137:6-carboxycellulose
Mekhanizm antibakterial'nogo deĭstviia monokarboksitselliulozy i drugikh ionoobmennykh proizvodnykh tselliulozy.