In vitro inhibition of Trichomonas vaginalis growth by some ortho-phenacyloxy-benzyl alcohols and their derivatives.
Some phenacyl ethers of different ortho-hydroxy-benzyl alcohols and analogues have been synthesized and tested for the in vitro activity towards Trichomonas vaginalis. The most active compounds had a minimum inhibitory concentration of 6.25 micrograms/ml and appeared to be of a certain interest as representative of a new type of anti-Trichomonas substances not containing a nitro group.
D000098:Acetophenones / Q000494:pharmacology*; D000818:Animals; D001592:Benzyl Alcohols / Q000494:pharmacology*; D001593:Benzyl Compounds / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D006131:Growth Inhibitors / Q000494:pharmacology*; D014246:Trichomonas vaginalis / Q000187:drug effects*
D000098:Acetophenones; D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D006131:Growth Inhibitors