title: Pharmacopsychological effects of flunarizine in geriatric patients with light brainorganic psychosyndrome. Preliminary communication.
abstract: The effects of the cerebral calcium antagonist flunarizine in 50 geriatric patients with light brainorganic psychosyndrome were determined in the course of a 12 weeks' placebo-controlled pharmacopsychological double-blind study. Factor analysis on the basis of 19 individual psychological tests served as multivariate evaluation model. Advantages of flunarizine became evident in factors 1 (contentedness), 3 (alertness) and 4 (good memory/sound sleep). The increased performance (factor 2) in both groups may well be due to a training effect and would, therefore, be artificial.
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005163:Factor Analysis, Statistical; D005260:Female; D005444:Flunarizine / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy*
chemical_list: D005444:Flunarizine