title: Extraskeletal myxoid chondrosarcoma: a histochemical and immunohistochemical study.
abstract: In reviewing a large series of soft tissue sarcomas, nine cases of extraskeletal myxoid chondrosarcoma have been retrieved. These tumours, which principally presented in middle-aged adults, have been examined histochemically to determine the heteroglycan content of their myxoid matrix and immunohistochemically for the presence of S-100 protein. The principal mucopolysaccharides identified were chondroitin-4 and 6-sulphate and keratan sulphate; each of the tumours was S-100 positive. The relevance of these findings to the histogenesis and differential diagnosis of these uncommon neoplasms is discussed.
mesh_terms: D000328:Adult; D010131:Aminosalicylic Acid; D002813:Chondrosarcoma / Q000032:analysis* / Q000401:mortality / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D009418:S100 Proteins / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000032:analysis* / Q000401:mortality
chemical_list: D009418:S100 Proteins; D010131:Aminosalicylic Acid