title: Presence of viral and inframicrobial germs detected by immunofluorescence reaction in 0-5-year-old children with acute respiratory infections.
abstract: The presence of viral and/or inframicrobial antigens was investigated by the immunofluorescence (IF) technique in exfoliated pharyngeal cells collected from 85 children aged 0-5 years, with acute infections of the upper or lower respiratory tract. Positive IF reactions were recorded in 83% of the children with bronchopneumonia, 81.8% of those with acute pharyngitis, 77.7% of those with acute upper respiratory tract infections and 66.6% of those with acute bronchitis. In 68.75% of the IF-positive cases 2-5 different antigens were simultaneously visualized. Herpes and parainfluenza virus antigens appeared to be predominant. The proportion of positive IF reactions was much lower (20%) in a control group of 20 apparently healthy children, where a single viral antigen (parainfluenza 1) was detected.
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis*; D002675:Child, Preschool; D002690:Chlamydia Infections / Q000382:microbiology; D005455:Fluorescent Antibody Technique; D006801:Humans; D007106:Immune Sera; D007223:Infant; D009175:Mycoplasma Infections / Q000382:microbiology; D012016:Reference Values; D012141:Respiratory Tract Infections / Q000382:microbiology*; D012282:Rickettsia Infections / Q000382:microbiology; D014777:Virus Diseases / Q000382:microbiology
chemical_list: D000942:Antigens, Bacterial; D000956:Antigens, Viral; D007106:Immune Sera