[Human leukemias studied with monoclonal antibodies to erythroid cells].
Activity of monoclonal antibodies HAE3 and HAE9 specific for human erythroid cells to different leukemic cells is described. These monoclonals do not react with nonerythroid leukemic cells. HAE3 and HAE9 reactivities are similar to those of polyclonal monospecific antibodies against an antigen of erythroblasts--a surface antigenic marker of nucleated red cells and reticulocytes. Monoclonal antibodies HAE3 and HAE9 are proposed to be used in diagnosis of leukemias.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis* / Q000302:isolation & purification; D000918:Antibody Specificity; D000954:Antigens, Surface / Q000276:immunology*; D004900:Erythroblasts / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D006825:Hybridomas / Q000276:immunology; D007114:Immunization; D007938:Leukemia / Q000175:diagnosis*; D051379:Mice; D008807:Mice, Inbred BALB C; D013997:Time Factors
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface
Izuchenie leĭkozov cheloveka s pomoshch'iu monoklonal'nykh antitel k éritroidnym kletkam.