A possible split of antigen DQw1 identified by antiserum T3516.
One of the human class II antigens DQw1, which was officially recognized at the 9th International Histocompatibility Workshop in 1984, has a comparatively broad spectrum. One multiparous woman's serum was confirmed to have an antibody which shows a reaction pattern of short DQw1 or a split of DQw1. Our analysis was performed with a population study, two-dimensional gel electrophoresis and blocking experiment by monoclonal antibodies.
D000906:Antibodies / Q000032:analysis; D000911:Antibodies, Monoclonal; D000920:Antibody-Dependent Cell Cytotoxicity; D001402:B-Lymphocytes / Q000276:immunology; D001667:Binding, Competitive; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D005455:Fluorescent Antibody Technique; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis* / Q000145:classification / Q000276:immunology / Q000378:metabolism; D006801:Humans; D007106:Immune Sera; D007123:Immunoelectrophoresis, Two-Dimensional; D008285:Major Histocompatibility Complex; D009000:Monocytes / Q000276:immunology; D009500:Neutralization Tests; D011233:Precipitin Tests; D011247:Pregnancy
D000906:Antibodies; D000911:Antibodies, Monoclonal; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II; D007106:Immune Sera