Cell-extracellular matrix interactions in morphogenesis: an in vitro approach.
We briefly review evidence from in vitro models that supports a role for the extracellular matrix in two essential steps of organogenesis: the establishment of appropriate three-dimensional cell-to-cell relationships, and the determination of a correct cell polarity.
D000818:Animals; D002196:Capillaries / Q000166:cytology; D002478:Cells, Cultured; D003094:Collagen / Q000502:physiology; D005109:Extracellular Matrix / Q000502:physiology*; D007515:Islets of Langerhans / Q000166:cytology; D007668:Kidney / Q000166:cytology; D008954:Models, Biological; D009024:Morphogenesis; D010447:Peptide Hydrolases / Q000502:physiology; D010703:Phorbol Esters / Q000494:pharmacology
D010703:Phorbol Esters; D003094:Collagen; D010447:Peptide Hydrolases