[Genetic and molecular characteristics of the conjugative R-plasmids of S. typhimurium].
The molecular genetic properties of R plasmids from 8 strains of S. typhimurium isolated in hospitals of the Far East of the USSR were studied. It was shown that conjugative R plasmids of S. typhimurium were characterized by belonging to the Inc F1 group, rigorous control of replication, the fi+ type and the transfer frequency of 10(-3) to 10(-4) per a donor cell. The plasmid profile of the S. typhimurium strains was represented by 2 plasmids: conjugative with a molecular weight of about 64 MD and nonconjugative with a molecular weight of 2 MD. The conjugative R plasmids of the hospital strain VG 103 of S. typhimurium were characterized by molecular genetic identity. They were derivatives of the pVG 103 plasmid.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003227:Conjugation, Genetic; D003428:Cross Infection / Q000382:microbiology; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D008826:Microbial Sensitivity Tests; D008970:Molecular Weight; D010641:Phenotype; D011815:R Factors; D012480:Salmonella Infections / Q000382:microbiology; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification
D000900:Anti-Bacterial Agents
Geneticheskie i molekuliarnaia kharakteristika kon'iugativnykh R-plazmid S. typhimurium.