Malnutrition and the respiratory muscles.
Malnutrition reduces respiratory muscle mass and contractile force through atrophy of Type II fibers and impaired energy metabolism. Nutritional repletion restores respiratory muscle function, but may add to ventilatory work. Nutritional repletion also enhances weaning from mechanical ventilation.
D000818:Animals; D001835:Body Weight; D006224:Cricetinae; D003964:Diaphragm / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology; D008297:Male; D051379:Mice; D009132:Muscles / Q000503:physiopathology*; D009135:Muscular Diseases / Q000503:physiopathology; D009748:Nutrition Disorders / Q000503:physiopathology*; D009929:Organ Size; D051381:Rats; D013217:Starvation / Q000503:physiopathology