Arterial healing in rabbits following carbon dioxide laser endarterectomy.
CO2 laser open endarterectomy of small atherosclerotic vessels appears feasible. Under the conditions described, the endarterectomized arterial wall is not smooth but the thrombogenicity of the laser-treated surface is low, and the endothelial healing rapid. These advantages are to be weighed against the consequence of thermal injury, in particular, the late development of aneurysms. Before human clinical trials are made, further experimental studies are required to determine the best type of laser and optimal wave length to limit thermal injury.
D000818:Animals; D001012:Aorta, Abdominal / Q000503:physiopathology / Q000601:surgery / Q000648:ultrastructure; D001161:Arteriosclerosis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D004691:Endarterectomy / Q000379:methods*; D004730:Endothelium, Vascular / Q000503:physiopathology / Q000601:surgery / Q000648:ultrastructure; D053685:Laser Therapy / Q000009:adverse effects; D011817:Rabbits; D014945:Wound Healing