title: Serum alcohol levels, toxicology screens, and use of the breath alcohol analyzer.
abstract: The emergency physician sees a large number of patients with problems related to the ingestion of alcohol, drugs, and toxins, and must be prepared to deal with them in an efficient and cost-effective manner. This article discusses a rationale for ordering serum alcohol levels and toxicology screens, as well as use of the breath alcohol analyzer. A serum alcohol level should be reserved for patients in whom the alcohol level is necessary to confirm a diagnosis or to guide treatment. An alcohol level is indicated when alcohol use is combined with a significant alteration in mental status, multiple drug overdose, head injury, coma, major trauma, seizures, or psychosis. The breath alcohol analyzer is useful when rapid determination of alcohol levels is desired, particularly with coma or coexisting head trauma. A low or negative level in this case rapidly alerts the physician to the presence of another condition that may require additional testing. Toxicology screening should be performed when suspected drug or toxin ingestion is combined with coma, convulsions, head injury with altered mental status, unstable vital signs, alterations in acid-base or electrolyte status, or psychosis. The screen also may be used to determine the need for a specific antidote or means of increasing excretion of a toxin, or to determine the presence of a drug that should be quantified to guide management. Open communication with the laboratory and the use of rapid screening tests markedly increase the benefit of toxicology screening.
mesh_terms: D000042:Absorption; D000435:Alcoholic Intoxication / Q000097:blood; D001944:Breath Tests; D003128:Coma / Q000097:blood; D006259:Craniocerebral Trauma / Q000097:blood; D004630:Emergencies; D000431:Ethanol / Q000032:analysis / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques; D007700:Kinetics
chemical_list: D000431:Ethanol