Low dose urography with a low osmolar contrast medium.
In a double blind study of 100 consecutive patients routinely referred for urography, a conventional contrast medium (Isopaque cerebral) was compared at a dose of 180 mg I/kg body weight with a low osmolar contrast medium (Hexabrix 160) at a dose of 90 mg I/kg body weight. In spite of 50 per cent dose reduction, equally good diagnostic effect was achieved with Hexabrix as with the conventional contrast medium.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007463:Iodobenzoates; D007485:Ioxaglic Acid; D008297:Male; D008794:Metrizoic Acid / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D008875:Middle Aged; D009994:Osmolar Concentration; D011897:Random Allocation; D014283:Triiodobenzoic Acids / Q000008:administration & dosage / Q000009:adverse effects; D014567:Urography
D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D008794:Metrizoic Acid; C021342:methylglucamine metrizoate; D007485:Ioxaglic Acid