[Isolation and characteristics of an antibacterial substance produced by a strain of Streptococcus sp. Thom-1606. A study of the biological activity of the metabolic products of Streptococcus sp. Thom-1606].
The data on the biological properties of the culture fluid of Streptococcus strain sp. TOM-1606 are presented. The native preparation has been shown to possess the capacity for stimulating the rate of the clearance of the peritoneal cavity of mice from Staphylococcus aureus cells, strain MT-1, rif. r., found to be insensitive to the action of the above-mentioned preparation in vitro. The crude preparation produces a transitory bacteriostatic effect on the streptococcal and staphylococcal strains under study. The preparation produces a prolonged bacteriostatic effect only on Micrococcus luteus test strain. All these data suggest that the crude preparation contains at least two active principles.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001430:Bacteriocins; D051379:Mice; D008837:Micrococcus / Q000187:drug effects; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology; D010529:Peritoneal Cavity / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects; D013291:Streptococcus / Q000378:metabolism*; D013297:Streptococcus pyogenes / Q000187:drug effects; D013997:Time Factors
D000900:Anti-Bacterial Agents; D001430:Bacteriocins; D010406:Penicillins; C026129:tomicide
Vydelenie i kharakteristika antibakterial'noĭ substantsii, produtsiruemoĭ shtammom Streptococcus sp. TOM-1606. Izuchenie biologicheskoĭ aktivnosti produktov metabolizma Streptococcus sp. TOM-1066.