title: [Reactive perforating collagenosis. Apropos of a case and review of the literature].
abstract: We present the case of a patient with the clinical and histopathological diagnosis of Reactive Perforating Collagenosis, the first case described in the Venezuelan Dermatological literature. The most frequent histopathological and differential clinical diagnoses are reviewed with regard to Kyrle's disease, Elastosis Perforans Serpiginosa and Perforating Folliculitis. Clinically our patient presented with a papular eruption over an erythematous base on the right forearm and the dorsum of the right hand. On the lower third on its ventral aspect these papules adopted a linear distribution suggesting an isomorphic reaction. Histopathologically, the phenomena of transepithelial elimination was observed. Finally we reviewed the multiple treatment modalities described in the literature for this disease. We treated our patient with topical retinoic acid at a 0.05% concentration nightly for seven nights with excellent results. At the present time she is free of cutaneous lesions.
mesh_terms: D003094:Collagen / Q000378:metabolism; D003095:Collagen Diseases / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D005542:Forearm; D006225:Hand; D006801:Humans; D008875:Middle Aged; D012871:Skin Diseases / Q000175:diagnosis
chemical_list: D003094:Collagen
vernacular_title: Colagenosis perforante reactiva. A propósito de un caso y revisión de la literatura.