Allogeneic bone marrow transplantation for Philadelphia-chromosome positive acute lymphoblastic leukemia.
Allogeneic bone marrow transplantation (BMT) produced remission in three patients with Philadelphia-chromosome (Ph1)-positive acute lymphoblastic leukemia (ALL) in relapse. Two patients had remissions which lasted longer than two years. Since the prognosis of Ph1-positive ALL treated with conventional therapy is poor, BMT is indicated in first remission in this disease.
D000328:Adult; D016026:Bone Marrow Transplantation; D006086:Graft vs Host Disease / Q000209:etiology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000235:genetics / Q000628:therapy*; D008297:Male; D010677:Philadelphia Chromosome; D014184:Transplantation, Homologous