title: [Isolation of Tyr- mutants of facultative methylotrophic Pseudomonas sp. M].
abstract: A method for isolation of Tyr- mutants of facultative methylotrophic bacteria Pseudomonas sp. M which possess two tyrosine synthesis pathways is presented. The method is based on the two-step blocking of the tyrosine synthesis: the first step of the supplementary pathway of synthesis from phenylalanine, the second being the main pathway from 4-hydroxyphenylpyruvate.
mesh_terms: D001431:Bacteriological Techniques; D009154:Mutation; D010641:Phenotype; D011549:Pseudomonas / Q000235:genetics* / Q000378:metabolism; D014443:Tyrosine / Q000096:biosynthesis*
chemical_list: D014443:Tyrosine
vernacular_title: Poluchenie Tyr- mutantov fakul'tativnykh metiltrofnykh bakteriĭ Pseudomonas sp. M.