title: Diagnosis and management of fetal facial clefts.
abstract: Fetal facial clefts were identified sonographically in 12 cases, 10 (83%) of which had other structural anomalies. When a facial cleft is diagnosed prenatally a careful search of the fetus for associated anomalies is indicated. With the finding of an autosomal trisomy in four of the 10 cases (40%) with associated anomalies, cytogenetic amniocentesis is desirable to aid in diagnosis and subsequent obstetric management of these patients.
mesh_terms: D000328:Adult; D000649:Amniocentesis; D002971:Cleft Lip / Q000175:diagnosis*; D002972:Cleft Palate / Q000175:diagnosis*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014314:Trisomy; D014463:Ultrasonography