title: [Human T lymphocyte clones: a new approach for studying relations between the major histocompatibility complex and pathology].
abstract: Human T cell clones specific of, or restricted by, HLA molecules allow the definition of HLA molecule polymorphism. The advantages of this technical approach are: the definition of a functional polymorphism on the one hand, and the monospecificity of this definition of the other hand. Therefore human T cell clones are unique tools for defining functional epitopes borne by HLA molecules and playing a role in disease associated with HLA.
mesh_terms: D002999:Clone Cells; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008285:Major Histocompatibility Complex; D011110:Polymorphism, Genetic; D013601:T-Lymphocytes / Q000166:cytology*
chemical_list: D006680:HLA Antigens
vernacular_title: Les clones lymphocytaires T humains: une approche nouvelle de l'étude des relations du complexe majeur d'histocompatibilité avec la pathologie.