[Role of insulin in the regulation of the tubular reabsorption of glucose in the kidneys].
Glucose tubular transport in the kidneys in changes of insulin concentration in the blood was studied in acute and chronic experiments on dogs. Maximum glucose reabsorption in the kidneys was shown to remain unchanged in the stimulation of insulin secretion or depletion of insular function (alloxan diabetes). Neither did the administration of insulin into the renal artery at doses of 0.02-0.04 U/min for 30 min. influence glucose reabsorption which rose during hormone infusion at doses of 0.4-0.5 U/min only.
D000042:Absorption; D000818:Animals; D001692:Biological Transport; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005919:Glomerular Filtration Rate; D005947:Glucose / Q000008:administration & dosage / Q000378:metabolism*; D007261:Infusions, Intra-Arterial; D007328:Insulin / Q000008:administration & dosage / Q000502:physiology*; D007684:Kidney Tubules / Q000378:metabolism*; D012077:Renal Artery
D007328:Insulin; D005947:Glucose
Znachenie insulina v reguliatsii kanal'tsevoĭ reabsorbtsii gliukozy v pochkakh.