Epidemic Reiter's syndrome following an outbreak of shigellosis.
We prospectively studied the occurrence of Reiter's syndrome (RS) or reactive arthritis (ReA) in 205 of 349 cruise-ship passengers who attended a buffet ashore and developed Shigella flexneri 2a enteritis. Five passengers probably had RS/ReA and 16 were possible or doubtful cases of RS/ReA. HLA-B27 was identified in 4 of 5 probable RS cases, but was not present in any of the 16 possible or doubtful cases nor in any of 20 passengers (controls) without any symptoms of RS/ReA. There was no statistically significant difference in the frequency of B7-Creg antigens in persons with possible or doubtful RS/ReA (9/16) compared to controls (8/20).
D000328:Adult; D000368:Aged; D016918:Arthritis, Reactive / Q000453:epidemiology* / Q000209:etiology; D004196:Disease Outbreaks / Q000453:epidemiology*; D004293:Dominican Republic; D004405:Dysentery, Bacillary / Q000150:complications / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000091402:Prohibitins; D011446:Prospective Studies; D012763:Shigella flexneri; D014481:United States