Experience of a Canadian multi-organ transplant service.
Organ transplantation has become the treatment of choice for selected patients with end-stage failure of the heart, liver or kidneys. The expanding role for organ transplantation, however, has led to a corresponding increase in the complexity of patient management. In response to these changes, University Hospital, London, Ont., has established an interdisciplinary multi-organ transplant service (MOTS). MOTS coordinates donor organ procurement and patient management. Donor organs have been retrieved from as far south as Dalton, Georgia, as far west as Calgary and as far east as Halifax. As of Dec. 31, 1985, 485 transplants had been performed, including 387 kidney transplants, 51 heart transplants, 3 heart/lung transplants, 43 liver transplants (in adults and children) and 1 pancreas transplant. With current immunosuppressive protocols MOTS projects 1-year patient survival rates of 95% after kidney transplantation, 88% after heart transplantation and 81% after liver transplantation. Patient rehabilitation has been excellent.
D000328:Adult; D002648:Child; D003365:Costs and Cost Analysis; D003524:Cyclosporins / Q000627:therapeutic use; D006084:Graft Rejection / Q000187:drug effects; D006680:HLA Antigens; D016027:Heart Transplantation; D006784:Hospitals, Teaching / Q000458:organization & administration*; D006785:Hospitals, University / Q000458:organization & administration*; D006801:Humans; D016030:Kidney Transplantation; D016031:Liver Transplantation; D008875:Middle Aged; D009864:Ontario; D016035:Pancreas Transplantation; D014019:Tissue Donors; D014184:Transplantation, Homologous / Q000191:economics / Q000379:methods
D003524:Cyclosporins; D006680:HLA Antigens