title: A genetic sexing strain of Anopheles quadrimaculatus, species A.
abstract: A genetic sexing strain of a mosquito, Anopheles quadrimaculatus, Species A, was synthesized for the preferential elimination of females during the egg stage. Malathion susceptibility was used as a conditional lethal, and the dominant malathion-resistance allele was linked to the Y chromosome via a radiation-induced reciprocal translocation involving the terminal end of the right arm of chromosome 3 and the Y chromosome. Examination of mitotic chromosomes and salivary polytene chromosomes revealed the precise nature of the translocation. Genetic leakage, through recombination, in the strain was very low (0.02%).
mesh_terms: D000818:Animals; D000852:Anopheles / Q000235:genetics*; D005260:Female; D007305:Insecticide Resistance / Q000235:genetics; D007621:Karyotyping / Q000662:veterinary; D008294:Malathion; D008297:Male; D010572:Pest Control, Biological / Q000379:methods*; D011995:Recombination, Genetic; D014178:Translocation, Genetic
chemical_list: D008294:Malathion