What's new in cellular cation exchange and humoral factors in primary hypertension?
In essential hypertension abnormalities of cellular Na+ and Ca++ handling have been described. The latter disturbance probably offers an explanation for the increased vasoconstriction in essential hypertension. The etiology of those disturbances in cellular Na+ and Ca++ metabolism may be related to genetic disturbances of membrane transport, or to a humoral factor influencing cellular cation metabolism.
D002118:Calcium / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000378:metabolism*; D045283:Natriuretic Agents / Q000097:blood; D012964:Sodium / Q000378:metabolism*
D045283:Natriuretic Agents; D012964:Sodium; D002118:Calcium