Critique of the extracranial-intracranial bypass study.
The potential benefit of extracranial-intracranial anastomosis was evaluated by a multicenter international cooperative study headed by the group in London, Ontario, Canada. The final conclusion of the study was that the extracranial-intracranial anastomosis did not provide any benefit over the treatment with aspirin. Several objections and shortcomings have been identified in this study. In our evaluation it cannot be concluded that EC-IC bypass surgery is not effective in reducing stroke in all patient populations.
D002548:Cerebral Revascularization; D002561:Cerebrovascular Disorders / Q000601:surgery; D002986:Clinical Trials as Topic; D006801:Humans