[Experience in analyzing the functional structure of thermogenesis based on pharmacologic testing].
In white rats both adapted and unadapted to cold and in lemmings the total heat production and skeletal muscles contractile activity under noradrenaline and propranolol were estimated at different ambient temperatures. In rats, the regulatory and adaptive changes of heat production occur due to a significant extension of adrenergically modulated part of contractile thermal effect in muscles, as well as to increased nonshivering thermogenesis. In lemmings, the adaptability to cold is maintained chiefly by nonshivering thermogenesis and leads to no alterations in muscle energetics.
D000064:Acclimatization / Q000187:drug effects*; D000818:Animals; D003411:Arvicolinae / Q000502:physiology*; D001833:Body Temperature Regulation / Q000187:drug effects*; D003080:Cold Temperature; D004576:Electromyography; D009119:Muscle Contraction / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology*; D010101:Oxygen Consumption / Q000187:drug effects; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D013045:Species Specificity
D011433:Propranolol; D009638:Norepinephrine
Opyt analiza funktsional'noĭ struktury termogeneza na osnove farmakologichskogo testirovaniia.