title: Suitability of urethane anesthesia for physiopharmacological investigations. Part 3: Other systems and conclusions.
abstract: The suitability of urethane anesthesia for physiopharmacological experiments in various systems is briefly reviewed. Urethane anesthesia appears to be suitable for various types of studies on respiratory function and on reflex activation of motility of the urinary bladder and some sections of the intestinal tract. However, urethane produces a variety of potentially disturbing side-effects at endocrine and renal level.
mesh_terms: D000311:Adrenal Glands / Q000187:drug effects / Q000502:physiology; D000403:Airway Resistance / Q000187:drug effects; D000758:Anesthesia; D000818:Animals; D001646:Bile / Q000378:metabolism; D004064:Digestive System / Q000187:drug effects; D004068:Digestive System Physiological Phenomena; D004702:Endocrine Glands / Q000187:drug effects / Q000502:physiology; D005260:Female; D005744:Gastric Acid / Q000378:metabolism; D005769:Gastrointestinal Motility / Q000187:drug effects; D013006:Growth Hormone / Q000378:metabolism; D007668:Kidney / Q000187:drug effects / Q000502:physiology; D007700:Kinetics; D007986:Luteinizing Hormone / Q000378:metabolism; D009119:Muscle Contraction / Q000187:drug effects; D010060:Ovulation / Q000187:drug effects; D010121:Oxytocin / Q000378:metabolism; D010600:Pharmacology; D010902:Pituitary Gland / Q000187:drug effects / Q000502:physiology; D011388:Prolactin / Q000378:metabolism; D012083:Renin / Q000378:metabolism; D012119:Respiration / Q000187:drug effects; D012143:Respiratory Physiological Phenomena; D014520:Urethane / Q000008:administration & dosage / Q000494:pharmacology*; D014554:Urination / Q000187:drug effects; D014667:Vasopressins / Q000378:metabolism
chemical_list: D014667:Vasopressins; D014520:Urethane; D010121:Oxytocin; D011388:Prolactin; D007986:Luteinizing Hormone; D013006:Growth Hormone; D012083:Renin