title: Portable thermogram technique for topically applied benzydamine cream in acute soft-tissue injuries.
abstract: A double-blind, parallel trial was undertaken with 3% benzydamine cream compared with a matching placebo, on patients suffering acute soft-tissue injuries. 21 patients received active material and 22 received placebo material. Patients applied the cream lightly 6 times a day for 6 days. Assessments were made (by the same physician) on days 0, 2, 4 and 6, and signs and symptoms were graded as "absent", "slight", "moderate" or "severe". Thermograms were taken on day 0 and day 6. The results showed significant relief of spontaneous pain, significant reduction in tenderness on pressure and in swelling on days 2, 4 and 6 of the trial, and a significant reduction in functional impairment on days 4 and 6, in the patients who had received the 3% benzydamine cream.
mesh_terms: D000287:Administration, Topical; D001591:Benzydamine / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D011720:Pyrazoles / Q000627:therapeutic use*; D013817:Thermography / Q000379:methods*; D014947:Wounds and Injuries / Q000188:drug therapy*
chemical_list: D011720:Pyrazoles; D001591:Benzydamine