title: A product of the C4B locus lacking hemolytic activity.
abstract: An unusual C4B allotype, C4B 4I, was identified in a study of C4 polymorphism in Japanese. This variant was defined as C4B using a murine monoclonal antibody specific for the C4d region of C4B. Hemolytic assay, however, revealed that the C4 variant, C4 BI was hemolytically inactive in contrast to other well-defined C4B locus products.
mesh_terms: D000483:Alleles; D000911:Antibodies, Monoclonal; D002874:Chromosome Mapping; D003181:Complement C4 / Q000032:analysis / Q000235:genetics*; D006461:Hemolysis; D006462:Hemolytic Plaque Technique; D006801:Humans; D007122:Immunoelectrophoresis
chemical_list: D000911:Antibodies, Monoclonal; D003181:Complement C4