The use of PhEA 34c in trabeculectomy.
PhEA 34c, a 1.9% solution of sodium hyaluronate (Healon = 1.0%) was injected intracamerally and between the scleral and conjunctival flaps after trabeculectomy in 15 eyes, while randomized controls received balanced salt solution (BSS). Anterior chamber depths in both groups in the early postoperative period were significantly different from baseline measurements, but were not different between the two groups at any interval. PhEA 34c did not prevent postoperative flat or shallow anterior chambers. There was no significant difference in the rate of success between the two groups for the duration of the study, but five patients in the PhEA 34c group developed loculated blebs.
D000867:Anterior Chamber / Q000473:pathology; D002986:Clinical Trials as Topic; D005260:Female; D005901:Glaucoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D011183:Postoperative Complications; D011184:Postoperative Period; D011897:Random Allocation; D014129:Trabecular Meshwork / Q000601:surgery*
D006820:Hyaluronic Acid