title: Bacteriostatic activity of bovine milk lactoferrin against mastitic bacteria.
abstract: The bacteriostatic activity of bovine lactoferrin (Lf) against mastitic bacteria was assessed with an in vitro microassay. The most susceptible species was Escherichia coli; all of the 35 isolates tested were susceptible to bacteriostasis by apo-Lf (0.1 mg ml-1), although a few strains showed a lower degree of inhibition. Heterogeneity among strains was more pronounced among 10 isolates of Staphylococcus aureus, four of which were apparently unaffected by apo-Lf (1 mg ml-1). Under the same conditions, Streptococcus agalactiae (six isolates) and Str. uberis (five isolates) resisted the bacteriostatic action of apo-Lf.
mesh_terms: D000818:Animals; D002417:Cattle; D004926:Escherichia coli / Q000254:growth & development; D007781:Lactoferrin / Q000502:physiology*; D007782:Lactoglobulins / Q000502:physiology*; D008413:Mastitis / Q000382:microbiology*; D008892:Milk / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000254:growth & development; D013291:Streptococcus / Q000254:growth & development; D013292:Streptococcus agalactiae / Q000254:growth & development
chemical_list: D007782:Lactoglobulins; D007781:Lactoferrin