title: Expression of the c-myb proto-oncogene during cellular proliferation.
abstract: In several cell types, messenger RNA levels of the nuclear proto-oncogene c-myb vary as a function of cellular proliferation; a transient increase in c-myb steady-state mRNA, mediated by post-transcriptional mechanisms, occurs during cell-cycle progression. In contrast, both quiescent and proliferating immature thymocytes contain exceptionally high levels of c-myb mRNA as a consequence of increased c-myb transcription.
mesh_terms: D000818:Animals; D002060:Bursa of Fabricius / Q000166:cytology; D002453:Cell Cycle; D002478:Cells, Cultured; D002645:Chickens; D005786:Gene Expression Regulation; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D011519:Proto-Oncogenes; D012333:RNA, Messenger / Q000235:genetics; D013950:Thymus Gland / Q000166:cytology; D014158:Transcription, Genetic
chemical_list: D011518:Proto-Oncogene Proteins; D012333:RNA, Messenger