title: Scalp neoplasm associated with cranium bifidum in a 24-week human fetus.
abstract: Prenatal ultrasonography at 24 weeks disclosed a fetus with a large mass protruding from the occiput. The mass was an invasive, undifferentiated mesenchymal neoplasm of the scalp associated with a defect in the occipital bone (cranium bifidum). The tumor may have derived from neural crest at the site of rhombencephalic closure. The tumor itself would seem to be a sporadic event, but the cranium bifidum may imply a recurrence risk of 2-3% for future pregnancies.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009436:Neural Tube Defects / Q000175:diagnosis / Q000378:metabolism; D009777:Occipital Bone / Q000002:abnormalities*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D009418:S100 Proteins / Q000378:metabolism; D012535:Scalp; D012878:Skin Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000378:metabolism; D014463:Ultrasonography
chemical_list: D009418:S100 Proteins