Human renin: a new class of inhibitors.
A new class of human renin inhibitor is described, containing a novel analogue of the peptide bond. High inhibitory potency was observed for octapeptide-length substrate analogues but inhibition progressively weakened as the molecule was shortened from the amino terminal end.
D000595:Amino Acid Sequence; D000808:Angiotensinogen / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D008433:Mathematics; D009842:Oligopeptides / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D000092502:Renin Inhibitors
D000808:Angiotensinogen; D009842:Oligopeptides; D000092502:Renin Inhibitors; C047174:BW 633C