Giant cell fibroblastoma: an immunohistochemical study.
Giant cell fibroblastoma is a rare, benign soft tissue tumor occurring in childhood. A 34-year-old woman presented with a giant cell fibroblastoma involving the chest wall. Histologic features include an infiltrating spindle-cell tumor involving the dermis and subcutaneous fat containing characteristic sinusoidal spaces rimmed by spindle cells and multinucleate giant cells. Immunohistochemical studies support a fibrohistiocytic differentiation.
D000328:Adult; D005260:Female; D005350:Fibroma / Q000032:analysis* / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D012983:Soft Tissue Neoplasms / Q000032:analysis* / Q000473:pathology