title: [Evaluation of the effects of citicoline in chronic cerebrovascular diseases].
abstract: A double-blind random block trial was carried out on 58 patients suffering from chronic cerebrovascular diseases as defined by the "Ad Hoc Committee, Paris 1980". The trial was carried out to assess the effects of citicoline on chronic cerebrovascular disease. Particular attention was paid to the selection of the assessment tools (neuropsychological and psychological tests). Citicoline treatment brought about an improvement in awareness and perceptive-motor faculties. This effect can be attributed to an overall drug action on neural energy metabolism.
mesh_terms: D000368:Aged; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D002794:Choline / Q000031:analogs & derivatives*; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D003566:Cytidine Diphosphate Choline / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011581:Psychological Tests; D011897:Random Allocation
chemical_list: D003566:Cytidine Diphosphate Choline; D002794:Choline
vernacular_title: Valutazione degli effetti della citicolina nella malattia cerebro-vascolare cronica.