[A new serologic reaction in patients with polymyalgia rheumatica and/or giant cell arteritis].
Fresh sera from patients with active polymyalgia rheumatica and/or giant cell arteritis are fixing the complement components C4 and C3 to structures of the medulla of rat kidney tissue as demonstrated by the indirect immunofluorescent technique. This PMR-associated reaction is also a useful tool in monitoring disease activity, as it becomes negative under effective treatment with steroids.
D000818:Animals; D001167:Arteritis / Q000276:immunology*; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D003168:Complement Fixation Tests; D005455:Fluorescent Antibody Technique; D006801:Humans; D007679:Kidney Medulla / Q000276:immunology; D011111:Polymyalgia Rheumatica / Q000276:immunology*; D051381:Rats; D012698:Serologic Tests
D003176:Complement C3; D003181:Complement C4
Eine neue serologische Reaktion bei Patienten mit Polymyalgia rheumatica und/oder Riesenzellarteriitis.