title: [Possibilities for use of monoclonal antibodies in gynecology and obstetrics].
abstract: It is demonstrated the theory of hybridoma technology and the production of monoclonal antibodies. Hybridomas can be obtained by fusion of spleen cells from Balb/c mice immunized with certain antigens and of myeloma cells, which produced monoclonal antibodies after cloning, culturing and recloning. The attraction of monoclonal antibodies is against polyclonal antibodies that all antibodies from one cell clon are equal with regard to primary structure, specificity and affinity to certain antigen. The application of monoclonal antibodies leads to an improvement of immunologic diagnostical methods. Special proceedings may expected in the fields of immunology of tumors, research of infertility and immunology of fetomaternal relationship.
mesh_terms: D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D003271:Contraceptive Agents, Female; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis*; D005833:Genital Neoplasms, Female / Q000175:diagnosis; D006801:Humans; D006825:Hybridomas; D007124:Immunoenzyme Techniques; D007247:Infertility, Female / Q000175:diagnosis; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis*; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D011259:Pregnancy Tests, Immunologic
chemical_list: D000911:Antibodies, Monoclonal; D003271:Contraceptive Agents, Female
vernacular_title: Anwendungsmöglichkeiten monoklonaler Antikörper in Gynäkologie und Geburtshilfe.