Growth cones in developing cultured cortical neurons.
Large numbers of growth cones were present in 6-day-old primary cultures of cerebral hemispheres from fetal rats. The average size of the growth cones was 24 by 28 microns. Many of these growth cones had both veil-like lamellipodia and filopodia. A few cones remained in 21-day-old cultures. These also had lamellipodia and filopodia. Ganglioside GM1 was present in both 6-day-old and 21-day-old cultured growth cones.
D000818:Animals; D002462:Cell Membrane / Q000502:physiology; D002478:Cells, Cultured; D002540:Cerebral Cortex / Q000166:cytology* / Q000502:physiology; D005455:Fluorescent Antibody Technique; D005677:G(M1) Ganglioside / Q000502:physiology*; D007124:Immunoenzyme Techniques; D007382:Intermediate Filaments / Q000502:physiology; D008563:Membrane Lipids / Q000502:physiology; D008855:Microscopy, Electron, Scanning; D009474:Neurons / Q000166:cytology / Q000502:physiology; D051381:Rats
D008563:Membrane Lipids; D005677:G(M1) Ganglioside