title: Progression of a benign epithelial ampullary tumor to adenocarcinoma.
abstract: Benign tumors of the extrahepatic biliary ducts are rare. The high recurrence rate following local resection of these benign tumors is well known, but the development of one into a malignant tumor has received little attention. The recurrence 4 years after local excision of a benign periampullary tumor that developed into a well-differentiated papillar adenocarcinoma is described in this case report. Radical resection was performed by means of a pancreatoduodenectomy. The literature concerning the progression of benign extrahepatic tumors to adenocarcinomas is reviewed.
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000473:pathology*; D014670:Ampulla of Vater / Q000473:pathology*; D001706:Biopsy; D003138:Common Bile Duct Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000473:pathology*