Urinary tract infections in pregnancy: Monuril single-dose treatment versus traditional therapy.
Today, it is widely accepted that a short-course or single-dose treatment with antimicrobial agents in pregnancy is the optimal therapy to minimize the risk of toxicity both for the mother and the fetus. A randomized trial comparing single-dose (3 g) treatment with fosfomycin trometamol (FT) versus pipemidic acid (200-gram doses b.i.d. for 7 days) in bacteriuric pregnant women is presented. The preliminary results show that single-dose FT has the same cure effect as conventional therapy with pipemidic acid.
D001437:Bacteriuria / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D005260:Female; D005578:Fosfomycin / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D009539:Nicotinic Acids / Q000627:therapeutic use*; D010876:Pipemidic Acid / Q000627:therapeutic use*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D011897:Random Allocation
D009539:Nicotinic Acids; D005578:Fosfomycin; D010876:Pipemidic Acid