Passive protection of NMRI mice with commercial, intravenously applicable human immunoglobulin IgG preparations against Serratia marcescens.
Three commercial, intravenously applicable human immunoglobulin IgG preparations (Gamma-Venin, Polyglobin, and Sandoglobulin) revealed low-titered O-agglutinins against the majority of 22 O-antigen reference strains of Serratia marcescens The three IgG preparations passively protected NMRI mice against intraperitoneal challenge with 8 of 19 selected, serologically defined O-antigen reference strains and clinical, nosocomially significant isolates of S. marcescens.
D000373:Agglutinins / Q000032:analysis; D000818:Animals; D004756:Enterobacteriaceae Infections / Q000517:prevention & control*; D005260:Female; D007116:Immunization, Passive / Q000379:methods*; D007074:Immunoglobulin G / Q000008:administration & dosage*; D008297:Male; D051379:Mice; D012706:Serratia marcescens / Q000276:immunology
D000373:Agglutinins; D007074:Immunoglobulin G