title: [Whole-body hyperthermia and hyperglycemia in the combined treatment of rectal cancer].
abstract: The paper is concerned with the results of combined therapy of 210 rectal cancer patients (stage III1 using hyperthermia, hyperglycemia and monochemotherapy (5-FU), and 6 patients with metastatic liver cancer who received intraportal chemotherapy. A selective damaging effect of hyperglycemia on a tumor cell was revealed. The use of hyperglycemia-hyperthermia-chemotherapy in the preoperative period was substantiated, the 3-year survival of 69 patients who had received single sessions of hyperthermia-hyperglycemia-monochemotherapy, was 77%. Positive results of intraportal administration of 5-FU were noted in the patients with metastatic liver cancer.
mesh_terms: D003131:Combined Modality Therapy / Q000379:methods; D005472:Fluorouracil / Q000008:administration & dosage; D005500:Follow-Up Studies; D005947:Glucose / Q000008:administration & dosage*; D006801:Humans; D006943:Hyperglycemia; D006979:Hyperthermia, Induced / Q000379:methods; D011182:Postoperative Care; D011300:Preoperative Care; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D012007:Rectum / Q000601:surgery; D013997:Time Factors; D014916:Whole-Body Irradiation / Q000379:methods
chemical_list: D005947:Glucose; D005472:Fluorouracil
vernacular_title: Obshchaia gipertermiia i giperglikemiia pri kombinirovannom lechenii raka priamoĭ kishki.