title: [Determination of fosfomycin in biological fluids by gas chromatography].
abstract: A method in gas chromatography is proposed to determine fosfomycin in biological and bacterial or cellular culture medium. This technique is carried out on capillary column OV 17-01 after "Flash Methylation" with a thermionic detector. The detection limit is about 1 microgram per millilitre of serum for a trial assay of 100 microliters. His characteristics have been furthered. The treatment by antibiotics generally associated with fosfomycin don't cause any chromatographic interference for plasmatic assays.
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D003470:Culture Media / Q000032:analysis*; D005578:Fosfomycin / Q000032:analysis* / Q000097:blood; D006801:Humans
chemical_list: D003470:Culture Media; D005578:Fosfomycin
vernacular_title: Détermination de la fosfomycine dans les milieux biologiques par chromatographie en phase gazeuse.