Immunocytochemical localization of estrogen-binding neurons in the songbird brain.
This study used monoclonal antibodies against estrogen receptor for the identification and localization of estrogen-binding cells in the avian brain. The distribution of estrogen-binding neurons in the songbird brain conformed to the general vertebrate pattern with highest labelling in hypothalamus and preoptic area. For the first time, estrogen-binding neurons were found in the song control system: these neurons might provide a substrate for the direct action of estrogen on the song system.
D000818:Animals; D000911:Antibodies, Monoclonal; D001717:Birds / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D002171:Canaries / Q000378:metabolism; D012739:Gonadal Steroid Hormones / Q000494:pharmacology; D007031:Hypothalamus / Q000378:metabolism; D007124:Immunoenzyme Techniques; D008297:Male; D011960:Receptors, Estrogen / Q000378:metabolism*; D013687:Telencephalon / Q000378:metabolism; D014828:Vocalization, Animal
D000911:Antibodies, Monoclonal; D012739:Gonadal Steroid Hormones; D011960:Receptors, Estrogen