title: Comparison of the prophylactic action of flupenthixol with placebo in lithium treated manic-depressive patients.
abstract: A double-blind cross-over trial of depot flupenthixol in recurrent manic depressive psychosis was carried out. All patients continued on lithium. Eleven patients completed the two-year trial. Flupenthixol appeared to have no prophylactic effect.
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy / Q000517:prevention & control*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D005475:Flupenthixol / Q000627:therapeutic use*; D006760:Hospitalization; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D013892:Thioxanthenes / Q000627:therapeutic use*
chemical_list: D013892:Thioxanthenes; D008094:Lithium; D005475:Flupenthixol