Advances in noninvasive cardiovascular imaging: implications for the anesthesiologist.
We have presented a review of recent advances in medical imaging which are relevant to the practice of anesthesia and associated research. The appropriate interpretation and use of the information derived from these noninvasive technologies can prevent unnecessary morbidity and mortality. Echocardiography remains the most advanced tool for noninvasive cardiac imaging because of its applicability for most cardiac disorders and its exquisite spatial resolution. Two-dimensional systems produce real time, dynamic, qualitative assessments of cardiac chamber morphology, size, thickness, and performance. The development of transesophageal echocardiography has brought this imaging power into the operating room for use by anesthesiologists. Recently developed quantitative and color-coded Doppler techniques will reveal intracardiac flow patterns and their alterations by anesthetics and surgery. These advantages are partially offset by inherent difficulties in quantifying echocardiographic data, and the need for highly trained operators for image reproduction. Nuclear cardiology and echocardiology are highly complementary. The scintigraphic methods identify myocardium at risk for infarction, confirm infarction when present, and produce quantitative, highly reproducible estimates of ventricular filling and performance. Time required to obtain data can be very brief for first-pass techniques, and these data are ideally suited for computer processing. Equilibrium studies require a larger dose of radioactive material, but provide excellent assessment of segmental wall motion. Preoperative studies with dipyridamole and Tl can indicate the patients truly at high risk for perioperative myocardial infarction. Monitoring and intensive care efforts may be better allocated with this information. No new technology in the past decade has stirred as much interest among clinicians as magnetic resonance imaging. Like echocardiography, it uses no ionizing radiation and is entirely noninvasive. But, unlike other imaging techniques, it utilizes multiple tissue characteristics to provide quick, highly resolved, tomographic images. Since bone is invisible to the magnetic resonance scanner, tissues inside bony structures are often best revealed with MRI. Nonimaging studies, i.e., spectroscopic data not spatially encoded, may prove to be the most important research currently underway in this field. In vivo estimates of intracellular functions, enzyme kinetics, and drug kinetics and metabolism are already in progress. The effects of anesthetic in the central nervous system and other organs may be explored in ways previously not possible.(ABSTRACT TRUNCATED AT 400 WORDS)
D000776:Anesthesiology; D004452:Echocardiography; D006321:Heart / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D006334:Heart Function Tests; D006801:Humans; D007430:Intraoperative Care; D009682:Magnetic Resonance Spectroscopy; D011877:Radionuclide Imaging