title: Biologic principles of bone induction.
abstract: This article provides a concise review of bone induction. Bone induction by demineralized bone matrix is a multistep cascade. The purification and elucidation of the chemistry of osteogens will improve bone grafting methods.
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001857:Bone Matrix / Q000502:physiology* / Q000637:transplantation; D002118:Calcium / Q000378:metabolism; D002454:Cell Differentiation; D002633:Chemotaxis; D019791:Guanidine; D006146:Guanidines / Q000494:pharmacology; D006801:Humans; D008938:Mitosis; D017830:Octoxynol; D009955:Ornithine Decarboxylase / Q000378:metabolism; D010012:Osteogenesis; D011092:Polyethylene Glycols / Q000494:pharmacology; D013045:Species Specificity
chemical_list: D006146:Guanidines; D011092:Polyethylene Glycols; D017830:Octoxynol; D000469:Alkaline Phosphatase; D009955:Ornithine Decarboxylase; D019791:Guanidine; D002118:Calcium