Experimental studies on peripheral nerve repair following early or delayed suture.
Early suture of the sciatic nerve in rats was compared with delayed suture performed after 2 weeks. The distal tract of the nerve was studied morphologically using semifine sections and computerised measurements of the number and diameters of regenerated fibres, and electrophysiologically by the measurement of nerve velocity conduction. The morphological examination did not reveal any substantial difference, while the velocity conduction tests showed better reinnervation following early suture.
D000818:Animals; D004594:Electrophysiology; D005071:Evoked Potentials; D009416:Nerve Regeneration; D009431:Neural Conduction; D051381:Rats; D012584:Sciatic Nerve / Q000293:injuries / Q000502:physiology / Q000601:surgery*; D013536:Suture Techniques; D013997:Time Factors