title: Genodermatoses with malignant potential.
abstract: Cowden's disease, which is characterized by multiple facial papules, gingival papillomas, acral papules, and other hamartomatous lesions, represents a genodermatosis with a high incidence of breast and thyroid carcinoma.
mesh_terms: D000328:Adult; D003111:Colonic Polyps / Q000235:genetics; D005260:Female; D005736:Gardner Syndrome / Q000235:genetics; D006223:Hamartoma Syndrome, Multiple / Q000235:genetics; D006801:Humans; D007223:Infant; D007417:Intestinal Polyps / Q000235:genetics; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000235:genetics; D011230:Precancerous Conditions / Q000235:genetics*; D012871:Skin Diseases / Q000235:genetics*; D012878:Skin Neoplasms / Q000235:genetics