Potential application of inhibin in male and female contraception.
After a review of investigations into the possible use of inhibin in the regulation of male and female fertility, briefly described and summarized in this article, the authors conclude that, at least in experimental animals, inhibin causes a significant reduction in testicular and epididymal spermatozoa in the male and luteal phase defect in the female. The precise mechanism by which inhibin brings about these effects is not known at present, and its elucidation will greatly help in the more effective use of inhibin.
D000818:Animals; D000906:Antibodies / Q000276:immunology; D003271:Contraceptive Agents, Female; D003272:Contraceptive Agents, Male; D010064:Embryo Implantation / Q000187:drug effects; D005260:Female; D006801:Humans; D007265:Inhibins / Q000276:immunology / Q000494:pharmacology / Q000652:urine; D008297:Male; D010060:Ovulation / Q000187:drug effects; D013091:Spermatogenesis / Q000187:drug effects; D013094:Spermatozoa / Q000276:immunology
D000906:Antibodies; D003271:Contraceptive Agents, Female; D003272:Contraceptive Agents, Male; D007265:Inhibins