title: Circulating gastrointestinal hormones in patients with flatulent dyspepsia, with and without gallbladder disease.
abstract: Fasting and post-prandial circulating levels of insulin, gastrin, gastric inhibitory polypeptide, pancreatic polypeptide and neurotensin were measured in patients with flatulent dyspepsia, with and without gallbladder disease and post-cholecystectomy. Levels were also measured in non-dyspeptic patients with gallbladder disease and normal controls. There were no consistent significant differences from controls for fasting and post-prandial responses in patients with a history of dyspepsia or those who experienced dyspepsia at the time of the test. In patients with gallbladder disease, with and without dyspepsia, there was a reduced neurotensin response compared to normal controls. It is concluded that circulating levels of these hormones are not related to symptoms of flatulent dyspepsia.
mesh_terms: D004415:Dyspepsia / Q000097:blood* / Q000150:complications / Q000209:etiology; D005260:Female; D005414:Flatulence / Q000097:blood* / Q000150:complications / Q000209:etiology; D005705:Gallbladder Diseases / Q000097:blood* / Q000150:complications; D005749:Gastric Inhibitory Polypeptide / Q000097:blood; D005755:Gastrins / Q000097:blood; D005768:Gastrointestinal Hormones / Q000097:blood*; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D009496:Neurotensin / Q000097:blood; D010191:Pancreatic Polypeptide / Q000097:blood
chemical_list: D005755:Gastrins; D005768:Gastrointestinal Hormones; D007328:Insulin; D009496:Neurotensin; D005749:Gastric Inhibitory Polypeptide; D010191:Pancreatic Polypeptide