title: [Merkel cell carcinoma with metastasis to the bone marrow].
abstract: The information concerning the concept of Merkel cell-neuron as a mechanoreceptor is revised. We are presenting an autopsy case in which a Merkel cell carcinoma infiltrated bone marrow and provoked its hypoplasia. An analysis of the literature let us see that the behavior of this neoplasia can be quiescent, but also could be very aggressive, with development of distant metastasis to lymph node, skin, liver, brain, bone and lung. These tumors can give origin to a paraneoplasic syndrome.
mesh_terms: D000232:Adenofibroma / Q000473:pathology*; D001855:Bone Marrow Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D010051:Ovarian Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*
vernacular_title: Carcinoma de células de Merkel con metástasis a médula ósea.