title: Inherent fragility of zona pellucida in certain patients included in an in-vitro fertilization programme.
abstract: OOcytes with a fractured zona pellucida were previously reported to occur with a 16% frequency when follicle puncture was carried out using a 20-ml syringe. This paper demonstrates a high rate of recurrence of fractured zonae in certain patients included in an in-vitro fertilization programme. We hypothesize an inherent zona fragility affecting these patients.
mesh_terms: D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D010063:Ovum / Q000502:physiology*; D015044:Zona Pellucida / Q000502:physiology*