[Correlations between the pharmacokinetic indices of the tranquilizer fenazepam in single and long-term administration to patients].
A high degree of correlation between experimentally established and theoretically calculated constant concentrations of phenazepam was revealed in blood plasma of patients. Due to experimental findings the employment of a single-dose drug administration with regard to previously stated effective-dose interval during dosage build-up made possible estimating the maximum allowable individual dosage which should yield a good therapeutic result without side effects.
D000284:Administration, Oral; D000328:Adult; D014151:Anti-Anxiety Agents; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000008:administration & dosage / Q000097:blood*; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D008875:Middle Aged; D013997:Time Factors
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D001569:Benzodiazepines; C017928:phenazepam
Korreliatsii mezhdu farmakokineticheskimi pokazateliami trankvilizatora fenazepama u bol'nykh pri ego odnokratnom i dlitel'nom prieme.