Complications of venous reconstruction in human orthotopic liver transplantation.
In 313 consecutive recipients of 393 orthotopic liver grafts, there were 51 (16.3%) and nine (2.9%) patients who had pre-existing portal vein and inferior vena cava abnormalities, respectively. These abnormalities required adjustments in the transplant operation and were a source of morbidity and mortality. The incidence of thrombosis of the reconstructed portal vein was 1.8%. Only three (0.8%) vena caval thromboses were seen after 393 liver replacements. Venous stenoses or disruptions were rare. Six women with the Budd-Chiari syndrome had liver replacement. Although this disorder is a veno-occlusive disease, five of the recipients achieved prolonged survival, only one had recurrence of disease, and three are alive after 2-6 years.
D000293:Adolescent; D000328:Adult; D006502:Budd-Chiari Syndrome / Q000401:mortality / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000098:blood supply; D016031:Liver Transplantation; D008297:Male; D011169:Portal Vein / Q000002:abnormalities / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology* / Q000401:mortality / Q000601:surgery; D012086:Reoperation; D013536:Suture Techniques; D013927:Thrombosis / Q000453:epidemiology / Q000601:surgery; D014019:Tissue Donors; D014682:Vena Cava, Inferior / Q000002:abnormalities / Q000601:surgery