title: Heat shock protein induction and induced thermal tolerance are independent in adult salamanders.
abstract: Ectothermic vertebrates become thermally tolerant (heat hardened) after exposure to heat shock. Eukaryotic cells show a similar response. Cellular thermal tolerance is correlated with the induction of heat shock proteins (hsps). We have investigated the relationship between heat hardening in salamanders and the induction of hsps in the tissues of these organisms. Although the synthesis of hsps can be induced in these animals by sublethal heat shocks, conditions required for hsp induction and heat hardening often do not coincide. We conclude that induced thermal tolerance in adult salamanders is independent of hsp induction in their tissues.
mesh_terms: D000064:Acclimatization; D000818:Animals; D001921:Brain / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000096:biosynthesis* / Q000302:isolation & purification; D006358:Hot Temperature; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008970:Molecular Weight; D013045:Species Specificity; D014562:Caudata / Q000502:physiology*
chemical_list: D006360:Heat-Shock Proteins