Conventional reanastomosis versus laser welding of rat uterine horns.
In this study we compared conventional surgical techniques with those of low-power CO2 lasers (output 140 mW; spot size 0.4 mm) used to weld transected rat uterine horns. On one side a microanastomosis was made by standard surgical technique of 8-0 nylon; the other side was "welded" either after doing the anastomosis with 8-0 sutures or without any anastomotic sutures. Histologic sections obtained from rats' uteri treated with conventional and laser surgery showed that on the laser-treated sutured side there was less necrosis and inflammatory and giant cells. The animals that underwent laser welding without suturing had no necrosis, suppuration, or granulation; giant cells were not present. We conclude that in the tissue from the laser-treated animals, when compared with conventional and laser-with-suture surgery, histologic features indicate healing process by primary intention via an aseptic noninflammatory reaction.
D000818:Animals; D005069:Evaluation Studies as Topic; D005260:Female; D053685:Laser Therapy / Q000379:methods*; D008866:Microsurgery / Q000379:methods*; D051381:Rats; D013536:Suture Techniques; D013997:Time Factors; D014599:Uterus / Q000473:pathology / Q000601:surgery*