title: [Preventive use of antibiotics in kidney transplantation].
abstract: Antibiotic prophylaxis in kidney transplantation is controversial. In a prospective controlled study, 34 cadaveric kidney transplant recipients were investigated. Antibiotic prophylaxis was given in a random order to 16 patients whereas 18 without prophylaxis served as controlls. In 4 of 20 investigated clinical parameters statistically significant differences were found between both groups: the controlls happened to have better initial conditions; perioperative and postoperative better initial conditions; perioperative and postoperative infections were less frequent in the prophylaxis group and more antibiotics postoperatively were needed in the controlls. These findings indicate that antibiotic prophylaxis has a beneficial effect in kidney transplantation.
mesh_terms: D001431:Bacteriological Techniques; D002408:Catheters, Indwelling; D002435:Cefamandole / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D016030:Kidney Transplantation; D011292:Premedication; D011897:Random Allocation; D018805:Sepsis / Q000517:prevention & control; D013530:Surgical Wound Infection / Q000382:microbiology / Q000517:prevention & control*; D014552:Urinary Tract Infections / Q000517:prevention & control
chemical_list: D002435:Cefamandole
vernacular_title: Antibiotikaprophylaxe bei Nierentransplantation.