Dominant disorders with multiple organ involvement.
Diagnosis of the preceding disorders may be difficult because of their wide range of clinical expression. The genetic patterns of incontinentia pigmenti, incontinentia pigmenti achromians, and focal dermal hypoplasia are still unclear, and literature regarding this subject may be confusing. Therefore, it is necessary to observe strict clinical criteria for diagnosis of these syndromes, and genetic counseling of affected individuals and families should be undertaken with care.
D003937:Diagnosis, Differential; D004476:Ectodermal Dysplasia / Q000235:genetics*; D005489:Focal Dermal Hypoplasia / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007184:Incontinentia Pigmenti / Q000175:diagnosis / Q000235:genetics*; D010859:Pigmentation Disorders / Q000175:diagnosis / Q000235:genetics*; D014402:Tuberous Sclerosis / Q000175:diagnosis / Q000235:genetics*