Stereological studies of mitochondria during the implantation of mouse blastocytes.
The following stereological parameters of mitochondria were compared in trophoblast of 5 and 6 day blastocysts: volume density of inner membrane (Vim), outer membrane (Vom), matrix (Vmat), outer compartment (Voc), surface density of outer membrane (Som) and inner membrane (Sim). They were the basis to calculate the partition coefficient of matrix (Emm) and the partition coefficient of outer compartment (Eocm). On 6 day after fertilization we found statistically significant volume increase of Vim, Voc, Sim, Som, Eocm and volume decrease of Vom, Vmat and Emm. Mitochondria visual evaluation and stereological analysis made for both groups allow to classify them to metabolic transitional state.
D000818:Animals; D001755:Blastocyst / Q000648:ultrastructure*; D010064:Embryo Implantation / Q000187:drug effects; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D051379:Mice; D008807:Mice, Inbred BALB C; D008928:Mitochondria / Q000648:ultrastructure; D011247:Pregnancy; D013997:Time Factors; D014327:Trophoblasts / Q000648:ultrastructure
D004958:Estradiol