[The adhesive capacity of representative intestinal microflora in the continuous and split oral administration of cephalexin and erythromycin].
When cephalexin and erythromycin were administered intragastrically with intervals, adhesion of facultative pathogenic bacteria such as Klebsiella, Staphylococcus and E. coli to enterocytes of the small intestine in vitro was more pronounced than with their continuous administration with drinking water. The adhesive capacity of the staphylococcal strains resistant to the antibiotics was higher than that of the sensitive ones.
D000284:Administration, Oral; D000818:Animals; D001419:Bacteria / Q000187:drug effects*; D001422:Bacterial Adhesion / Q000187:drug effects*; D002506:Cephalexin / Q000008:administration & dosage*; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000008:administration & dosage*; D004926:Escherichia coli / Q000187:drug effects; D007422:Intestines / Q000382:microbiology*; D007709:Klebsiella / Q000187:drug effects; D008722:Methods; D051381:Rats; D013211:Staphylococcus aureus / Q000187:drug effects; D013997:Time Factors
D004917:Erythromycin; D002506:Cephalexin
Adgezivnaia sposobnost' predstaviteleĭ kishechnoĭ mikroflory pri nepreryvnom i drobnom oral'nom vvedenii tsefaleksina i éritromitsina.