[Serum ferritin levels in patients with hemolymphopathies and solid neoplasms in an advanced phase: a comparison with healthy subjects and liver cirrhosis patients].
The immunoenzyme method was used to measure serum ferritin levels in 55 patients with haemolymphopathies and advanced solid tumours. Patients were divided into five groups according to tumour type. 50 healthy subjects and 12 patients with cirrhosis of the liver were also studied. In 76% of the cancer patients ferritin levels were significantly higher than in the control group of healthy subjects (p less than 0.01). Only 8 of the patients studied had primary or secondary liver tumours. None of the cancer patients showed clinical or blood chemical signs of current acute or chronic liver disease. Furthermore 13 of the cancer patients had severe anaemia and were given multiple transfusions during hospitalisation. All the groups studied showed a significant (p less than 0.01) increase in mean ferritinaemia levels compared to the healthy control groups. There was also a significant difference between the mean value encountered in the liver cancer and cirrhosis groups. Both groups also showed significantly higher levels than the control group. In contrast no significant differences were noted between the mean values encountered in the individual cancer groups by means of variance analysis.
D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D007124:Immunoenzyme Techniques; D007938:Leukemia / Q000097:blood* / Q000175:diagnosis; D008103:Liver Cirrhosis / Q000097:blood* / Q000175:diagnosis; D008223:Lymphoma / Q000097:blood* / Q000175:diagnosis; D008297:Male; D009369:Neoplasms / Q000097:blood* / Q000175:diagnosis
D005293:Ferritins
Livelli serici di ferritina in pazienti affetti da emolinfopatie e neoplasie solide in fase avanzata: confronto con soggetti sani e pazienti affetti da cirrosi epatica.