title: Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast.
abstract: The two strands of the DNA molecule are complementary but not identical. Hence, upon semiconservative replication, different parental DNA strands are segregated to daughter cells. A molecular analysis suggests that the process of fission yeast mating-type interconversion uses asymmetry of the DNA strands to generate a regular lineage of cellular differentiation.
mesh_terms: D002453:Cell Cycle; D004261:DNA Replication; D004271:DNA, Fungal / Q000235:genetics*; D004718:Saccharomycetales / Q000235:genetics*; D012568:Schizosaccharomyces / Q000166:cytology / Q000235:genetics* / Q000254:growth & development
chemical_list: D004271:DNA, Fungal