title: Measurement in vitro of pulsatile arterial diameter using a helium-neon laser.
abstract: A noncontacting in vitro measurement of pulsatile arterial diameter using a scanning optical micrometer is described. The major component of this system is a He-Ne laser whose beam scans the pulsating artery to be measured. The laser micrometer was integrated into a pulsatile perfusion apparatus that imposed various hemodynamic conditions on excised canine vessels. The laser system reliably tracked the pulsating arterial diameter at a particular longitudinal site as well as at various increments in the presence of an experimentally created stenosis. The He-Ne laser measured the radial motion of canine arteries and various vascular substitutes anastomosed in an end-to-end fashion. From these novel measurements, calculations were made of arterial compliance and bending stress, two biomechanical parameters that are implicated as potential causes of anastomotic intimal hyperplasia and graft failure. Although this device is inherently limited to in vitro use, it is a potentially useful instrument for vascular physiology and biophysics.
mesh_terms: D000818:Animals; D001158:Arteries / Q000033:anatomy & histology*; D004285:Dogs; D006371:Helium; D006439:Hemodynamics; D007834:Lasers / Q000295:instrumentation; D008433:Mathematics; D009356:Neon; D011674:Pulse; D013314:Stress, Mechanical
chemical_list: D006371:Helium; D009356:Neon