Clear cell chondrosarcoma. A report of two cases and review of literature.
Two cases of clear cell chondrosarcoma located in the distal femur and proximal humerus are reported. Both patients were men aged 35 and 51 years. Their initial symptom was a pathologic fracture. Roentgenographically, one patient showed a purely lytic lesion and another lytic with centrally radiodensity. Microscopic examination revealed that the tumor cells have a centrally placed vesicular nucleus surrounded by a clear cytoplasm, with distinct boundaries. Their cytoplasm stained with S-100 protein by the peroxidase-antiperoxidase method. We found 36 reported cases (including the two reported here), and delineated the clinico-pathologic characteristics of the disease.
D000328:Adult; D001859:Bone Neoplasms / Q000032:analysis* / Q000000981:diagnostic imaging / Q000473:pathology; D002813:Chondrosarcoma / Q000032:analysis* / Q000000981:diagnostic imaging / Q000473:pathology; D005266:Femoral Neoplasms / Q000032:analysis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D006811:Humerus; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D011859:Radiography; D009418:S100 Proteins / Q000032:analysis*
D009418:S100 Proteins