[Experimental arterial microsutures. Evaluation of the risks of thrombosis using technetium 99-labeled heparin].
Following demonstration of a method of assay of circulation heparin by measurement of radioactivity after labelling with 99 m technetium, the technique was used to study effects of arterial microsuture on metabolism of heparin injected postoperatively. Results of a study involving rat aorta showed that local binding was maximum during the first half-hour and that abnormal consumption of heparin continued during the 6 hours following operation. These finding suggest that a risk of thrombosis probably persists throughout this postoperative period.
D000818:Animals; D001158:Arteries / Q000601:surgery*; D006493:Heparin / Q000378:metabolism*; D007700:Kinetics; D008866:Microsurgery; D011183:Postoperative Complications / Q000209:etiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012306:Risk; D013536:Suture Techniques; D013667:Technetium; D013927:Thrombosis / Q000097:blood / Q000209:etiology*
D013667:Technetium; D006493:Heparin
Microsutures artérielles expérimentales. Evaluation des risques de thrombose par l'héparine marquée au technétium 99.