title: [DNA repair in mammalian nerve cells. I. DNA synthesis in the neocortex of rats induced by gamma irradiation].
abstract: A study was made of the DNA synthesis in cerebral cortex of rats, aged 14 and 60 days, after gamma-irradiation in vivo in a dose of 7 Gy, the 3H-thymidine incorporation into DNA being determined.137 Cs-radiation induces additional DNA synthesis in the neocortex tissue and in neurons. In the cortex of 14 day-old rats, the induced DNA synthesis stops 2 hours after irradiation, whereas in the cortex of 60 day-old rats and in neurons of rats of both the age groups DNA synthesis is proceeding for 3-3.5 hours. Specificity of DNA reparation processes in non-dividing cells is discussed.
mesh_terms: D000375:Aging / Q000378:metabolism / Q000528:radiation effects; D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism / Q000528:radiation effects*; D004247:DNA / Q000096:biosynthesis / Q000528:radiation effects*; D004260:DNA Repair / Q000528:radiation effects*; D005720:Gamma Rays; D007700:Kinetics; D008297:Male; D009474:Neurons / Q000378:metabolism / Q000528:radiation effects*; D051381:Rats
chemical_list: D004247:DNA
vernacular_title: Reparatsiia DNK v nervnykh kletkakh mlekopitaiushchikh. I. Sintez DNK v neokortekse, indutsirovannyĭ gamma-oblucheniem krys.