Antifungal activity of ajoene derived from garlic.
The antifungal activity of six fractions derived from garlic was investigated in an in vitro system. Ajoene had the strongest activity in these fractions. The growth of both Aspergillus niger and Candida albicans was inhibited by ajoene at less than 20 micrograms/ml.
D000935:Antifungal Agents / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects* / Q000254:growth & development / Q000648:ultrastructure; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development / Q000648:ultrastructure; D004220:Disulfides / Q000494:pharmacology*; D005737:Garlic; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D013441:Sulfinic Acids / Q000494:pharmacology; D013454:Sulfoxides
D000935:Antifungal Agents; D004220:Disulfides; D010936:Plant Extracts; D013441:Sulfinic Acids; D013454:Sulfoxides; C006452:allicin; C048980:ajoene