title: Pharmacologic considerations in drug therapy in foals.
abstract: Rational drug therapy in the foal requires a sound knowledge of the pharmacodynamics and pharmacokinetics of various drugs as well as a thorough understanding of the physiologic differences that exist between the neonate and the adult and that may serve to alter drug disposition and, therefore, drug response. A summary of these physiologic factors with emphasis on the foal is presented and is followed by recommendations regarding the applied therapeutics of various antimicrobial agents.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000662:veterinary*; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses / Q000378:metabolism*; D007700:Kinetics; D014018:Tissue Distribution
chemical_list: D000900:Anti-Bacterial Agents