title: Immunological disorders of human pregnancy.
abstract: Three types of disorders of human pregnancy with a possible immune etiology have been discussed. Pre-eclampsia and recurrent abortion may result from a failure of a maternal immunoregulatory response to trophoblast but the evidence is incomplete and circumstantial. There are several fetal problems which may arise because of transfer of maternal allo-, iso-, or autoantibodies to the fetus. Third, maternal graft-versus-fetal-host disease occurs rarely and may present in a delayed and incomplete way as severe combined immunodeficiency.
mesh_terms: D000026:Abortion, Habitual / Q000276:immunology; D005260:Female; D006086:Graft vs Host Disease / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007154:Immune System Diseases / Q000150:complications* / Q000276:immunology; D008431:Maternal-Fetal Exchange; D011225:Pre-Eclampsia / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D014327:Trophoblasts / Q000276:immunology
chemical_list: D006680:HLA Antigens