title: [Genetics of the immune response of Karakul sheep immunized with E. coli and Salmonella vaccines. An analysis of the intensity of the immune response in 2d-generation and reverse-cross hybrids].
abstract: For the genetic analysis of the character of inheriting the immune response and the study of the possibility of immunoselection in astrakhan sheep, the test crossing of the previously selected and raised animals in different genetic combinations has been made. Regularities in inheriting the intensity of immune response in hybrids F2 and BC1 of astrakhan sheep, highly responsive to E. coli and Salmonella vaccines, confirm the dominant character of the capacity for intensive immune response. The second-generation hybrids obtained by the crossing of the animals, either highly responsive or weakly responsive to E. coli or Salmonella vaccine, show a high degree of concordance in their capacity for response to this antigen. This confirms the possibility for the immunoselection of sheep by their capacity for response to a given vaccine.
mesh_terms: D000818:Animals; D000937:Antigen-Antibody Reactions; D001428:Bacterial Vaccines / Q000276:immunology*; D003433:Crosses, Genetic; D004926:Escherichia coli / Q000276:immunology*; D007114:Immunization / Q000379:methods / Q000662:veterinary*; D010641:Phenotype; D012475:Salmonella / Q000276:immunology*; D012641:Selection, Genetic; D012756:Sheep / Q000235:genetics / Q000276:immunology*; D013997:Time Factors
chemical_list: D001428:Bacterial Vaccines
vernacular_title: Genetika immunnogo otveta karakul'skikh ovets pri immunizatsii koli-bakterioznoĭ i sal'monelleznoĭ vaktsinami. Analiz sily immunnogo otveta u gibridov vtorogo pokoleniia i obratnogo skreshchivaniia.