Campomelic syndrome: concepts of the bowing and shortening in the lower limbs.
A comprehensive study (bone roentgenography, arteriography, gross dissection, microscopy of the long bones, and biochemical study of proteoglycan-aggregates in the hyaline cartilage) of the lower limbs in a full-term stillborn with the campomelic syndrome was performed. Hyaline cartilage immaturity of the long bones, dysplasia of growth plates, focal shaft dysplasia, and a defective length of the posterior femur and crus muscles were revealed. The genesis of the bowing and shortening of the long bones in the lower limbs is discussed.
D000015:Abnormalities, Multiple / Q000473:pathology; D000792:Angiography; D005260:Female; D005269:Femur / Q000002:abnormalities; D005360:Fibula / Q000002:abnormalities; D006132:Growth Plate / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007866:Leg / Q000002:abnormalities* / Q000098:blood supply / Q000000981:diagnostic imaging; D009132:Muscles / Q000002:abnormalities; D013577:Syndrome; D013977:Tibia / Q000002:abnormalities