[Comparative evaluation of the results of the bicycle ergometry test in patients with stress stenocardia after treatment with propranolol and nifedipine].
The results of bicycle ergometry (BE) following administration of placebo, 80 mg propranolol (anaprilin), 30 mg nifedipine (corinfar) and a combination of 60 mg propranolol and 20 mg nifedipine were reviewed in coronary patients with angina pectoris of functional classes (FC) II-IV. Patients with FC-II angina showed the greatest increment in stress tolerance after nifedipine administration, and patients with FC-IV angina, after propranolol, apparently due to a predominance of the functional (coronaro-spastic) pathogenetic factor in the FC-II angina, and the organic factor, in angina of more severe functional classes. In patients belonging to FC-III, the two drugs had similar antianginal efficiency. Stress tolerance increased considerably after simultaneous administration of both drugs in all patients with angina of effort, irrespective of functional class.
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D001794:Blood Pressure; D004359:Drug Therapy, Combination; D005080:Exercise Test; D005500:Follow-Up Studies; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage / Q000627:therapeutic use*; D011433:Propranolol / Q000008:administration & dosage / Q000627:therapeutic use*
D011433:Propranolol; D009543:Nifedipine
Sravnitel'naia otsenka rezul'tatov veloérgometricheskoĭ proby u bol'nykh so stenokardieĭ napriazheniia posle priema propranolola i nifedipina.