Hemoglobin La Desirade alpha A2 beta 2 129 (H7) Ala----Val: a new unstable hemoglobin.
Hemoglobin La Desirade is a new unstable hemoglobin variant arising from the substitution of beta 129 (H7) Ala for Val. Hb La Desirade exhibits a low oxygen affinity and normal heme-heme interaction. The variant was found in two unrelated black families in association with Hb S, Hb C or beta o thalassemia.
D000409:Alanine / Q000502:physiology; D000595:Amino Acid Sequence; D044383:Black People; D002851:Chromatography, High Pressure Liquid; D006453:Hemoglobinopathies / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000032:analysis* / Q000502:physiology; D006801:Humans; D007525:Isoelectric Focusing; D010100:Oxygen / Q000378:metabolism; D010375:Pedigree; D014633:Valine / Q000502:physiology
D006455:Hemoglobins, Abnormal; C052162:hemoglobin La Desirade; D014633:Valine; D000409:Alanine; D010100:Oxygen