title: Glucose tolerance and lipid-lipoprotein levels in middle-aged powerlifters.
abstract: The purpose of this study was to obtain information regarding the effects of a form of strength training (powerlifting) on certain coronary artery disease (CAD) risk factors in middle-aged men. The risk factors studied were the plasma lipid-lipoprotein profile, glucose tolerance and plasma insulin levels, all of which have been shown to be favourably influenced by endurance training in middle-aged and older men. Five elite powerlifters (52 +/- 9 years) were compared to distance runners and sedentary controls of similar age with whom they were matched in terms of body fatness as estimated from skin-fold thickness measurements. The powerlifters had a significantly (P less than 0.01) lower HDL cholesterol (HDL-C) level (34 +/- 4 mg/100 ml) than the sedentary controls (48 +/- 12 mg/100 ml) and runners (54 +/- 8 mg/100 ml). The total cholesterol to HDL-C ratio, a good indicator of CAD risk, was 41% higher in the powerlifters than in the controls, and 57% higher than in the runners (both P less than 0.01). The total area under the glucose tolerance curve during an oral glucose tolerance test (OGTT) for the powerlifters was 74% higher than for the sedentary controls (P less than 0.05) and 229% higher than for runners (P less than 0.01). Similarly, the total area under the OGTT insulin curve for the powerlifters was 68% higher than for sedentary controls and 332% higher than for the runners (P less than 0.001). These findings suggest that middle-aged powerlifters, in marked contrast to endurance athletes, have an increased risk of developing CAD.
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000209:etiology; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D010809:Physical Fitness; D012306:Risk; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D007328:Insulin; D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol