title: Atypical progressive stroke syndrome associated with oral contraceptives and cigarette use.
abstract: We report a case of progressive multifocal intracranial distal arterial branch occlusive disease in a young adult who smoked heavily and used oral contraceptives. The distribution of the angiographic lesions and the associated telangiectasias and rete mirabile resemble Moya-Moya disease except for clearly absent proximal carotid arterial disease. This type of distal multifocal cerebral arterial occlusive pattern appears to be a very rare manifestation of cigarette and oral contraceptive use. The patient has remained without symptoms for greater than 3 years off oral contraceptives and cigarettes and on antiplatelet agents.
mesh_terms: D000328:Adult; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D012907:Smoking; D013577:Syndrome
chemical_list: D003276:Contraceptives, Oral