Early identification of renal problems in patients receiving chronic lithium treatment.
Serum beta 2-microglobulin and creatinine values were compared with creatinine clearance in 20 lithium-treated patients. beta 2-microglobulin, but not creatinine, correlated significantly with creatinine clearance, indicating that beta 2-microglobulin is a more sensitive test than serum creatinine for monitoring glomerular filtration rate in chronic lithium therapy.
D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood* / Q000378:metabolism; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced* / Q000175:diagnosis; D008094:Lithium / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D001613:beta 2-Microglobulin / Q000097:blood*
D001613:beta 2-Microglobulin; D008094:Lithium; D003404:Creatinine