[Changes in urinary serotonin in subjects treated with calcitonin].
In a first stage, the authors have evaluated the relationship between plasma calcitonin and urinary serotonin in patients presenting a chronic pathology, mostly of respiratory nature. The results have demonstrated that plasma calcitonin and urinary elimination of serotonin were increased (p less than 0.05) in patients presenting a chronic pathology, compared to 16 healthy patients of the same age and sex. In a second stage, the authors have evaluated the variations of urinary serotonin 24 hours after injection of 100 U MRC of calcitonin from salmon, in the same patients. The results showed (p less than 0.001) an increase of urinary serotonin at 24 hours. This increase is not observed after injection of eel or human calcitonin. The effect of the various calcitonin on serotonin metabolism is discussed.
D000368:Aged; D002116:Calcitonin / Q000009:adverse effects* / Q000097:blood; D002908:Chronic Disease; D005260:Female; D005483:Flushing / Q000209:etiology; D006801:Humans; D008171:Lung Diseases / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012701:Serotonin / Q000378:metabolism / Q000652:urine*
D012701:Serotonin; D002116:Calcitonin
Variation de la sérotonine urinaire chez des sujets traités par la calcitonine.