Agglutination and mating activity of the MF alpha 2-encoded alpha-factor analog in Saccharomyces cerevisiae.
The MF alpha 2-encoded Asn-5,Arg-7 alpha-factor-like peptide has been shown shown to have similar activity to Gln-5,Lys-7 alpha-factor in morphogenesis and growth arrest studies (S. Raths, P. Shenbagamurthi, F. Naider, and J. M. Becker, J. Bacteriol. 168:1468-1471, 1986). We tested the Asn-5,Arg-7 peptide in agglutination and mating assays and found that its activity was similar to or slightly less than that of the Gln-5,Lys-7 alpha-factor. The Asn-5,Arg-7 alpha-factor-like peptide is thus the most active analog of the Gln-5,Lys-7 alpha-factor known.
D002448:Cell Adhesion; D002453:Cell Cycle; D005796:Genes; D005800:Genes, Fungal; D000072235:Mating Factor; D010455:Peptides / Q000235:genetics / Q000502:physiology*; D012098:Reproduction; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000502:physiology*
D010455:Peptides; D000072235:Mating Factor