Drug therapy of portal hypertension.
Portal hypertension is the result of increased flow and increased resistance in the portal system. Pharmacological therapy is aimed at altering these factors by the use of vasoconstrictors to reduce flow and vasodilators to decrease intrahepatic resistance. The current status of pharmacological agents to achieve these effects is reviewed.
D000818:Animals; D006801:Humans; D006975:Hypertension, Portal / Q000188:drug therapy*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents