[Isolation and properties of the Ca2+, phospholipid-dependent protein kinase from the substantia grisea of the rat brain in the early stage of exposure to ionizing radiation].
Ca2+, phospholipid-dependent proteinkinase was isolated from intact and exposed (1 h following whole body X-irradiation with a dose of 0.21 C/kg) gray substance of rat brain, and the dependence of this enzyme on pH and temperature, and substrate specificity were studied. Changes were shown to occur in some Ca2+, phospholipid-dependent proteinkinase properties under the effect of X-radiation while the substrate specificity remained unchanged.
D000818:Animals; D001921:Brain / Q000201:enzymology / Q000528:radiation effects*; D005260:Female; D006863:Hydrogen-Ion Concentration; D008297:Male; D010766:Phosphorylation; D011493:Protein Kinase C / Q000302:isolation & purification / Q000378:metabolism / Q000528:radiation effects*; D051381:Rats; D013379:Substrate Specificity / Q000528:radiation effects; D013696:Temperature; D014916:Whole-Body Irradiation
D011493:Protein Kinase C
Vydelenie i nekotorye svoĭstva Ca2+, fosfolipid-zavisimoĭ proteinkinazy serogo veshchestva golovnogo mozga krys na rannem étape vozdeĭstviia ioniziruiushcheĭ radiatsieĭ.