Non-phosphorylated and phosphorylated neurofilaments in hypothyroid rat cerebellum.
Purkinje cell baskets in hypothyroid rat cerebellum were studied with antibodies reacting with phosphorylated or non-phosphorylated neurofilament epitopes. Compared to normal rats, Purkinje cell baskets were fewer in number and less developed in hypothyroid rat cerebellum. However, no differences were observed as to their immunoreactivity with monoclonal antibodies reacting with phosphorylated or non-phosphorylated neurofilament epitopes.
D000818:Animals; D005455:Fluorescent Antibody Technique; D007037:Hypothyroidism / Q000378:metabolism* / Q000473:pathology; D007381:Intermediate Filament Proteins / Q000378:metabolism*; D010766:Phosphorylation; D011689:Purkinje Cells / Q000378:metabolism* / Q000473:pathology; D051381:Rats
D007381:Intermediate Filament Proteins