Liver and muscle proteolytic activity in male growing rats fed a field bean (Vicia faba L.) diet.
Total liver cathepsin A and D and gastrocnemius acid proteolytic activities have been evaluated in male growing rats fed ad libitum over periods of 15 and 30 days on 20%-protein diets containing either casein or raw field bean (Vicia faba L.) as protein sources. It has been found that, compared to the control casein-fed rats, those fed the legume diet exhibited a marked reduction (p less than 0.05) in the rate of growth and protein efficiency rate; liver proteolytic activity increased with ageing in the two dietary treatments and was found to be significantly higher (p less than 0.05) in the legume-fed rats. However, muscle proteolytic activity decreased with ageing and proved significantly increased (p less than 0.05) in the legume-fed rats.
D000818:Animals; D002268:Carboxypeptidases / Q000378:metabolism; D043402:Cathepsin A; D002402:Cathepsin D / Q000378:metabolism; D002403:Cathepsins / Q000378:metabolism; D004044:Dietary Proteins / Q000633:toxicity*; D007887:Fabaceae / Q000633:toxicity*; D006128:Growth; D008099:Liver / Q000201:enzymology; D008297:Male; D009132:Muscles / Q000201:enzymology; D010447:Peptide Hydrolases / Q000378:metabolism*; D014674:Plant Proteins, Dietary / Q000633:toxicity*; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains
D004044:Dietary Proteins; D014674:Plant Proteins, Dietary; D002268:Carboxypeptidases; D002403:Cathepsins; D010447:Peptide Hydrolases; D043402:Cathepsin A; D002402:Cathepsin D