Thrombin and trypsin activate phospholipase C in human platelets via a proteolytic-mediated pathway.
D001792:Blood Platelets / Q000187:drug effects* / Q000201:enzymology; D004789:Enzyme Activation / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D010447:Peptide Hydrolases / Q000494:pharmacology; D013917:Thrombin / Q000494:pharmacology*; D014357:Trypsin / Q000494:pharmacology*; D010738:Type C Phospholipases / Q000097:blood*
D010738:Type C Phospholipases; D010447:Peptide Hydrolases; D014357:Trypsin; D013917:Thrombin