[Hemodynamic findings using high-frequency jet ventilation in major surgery].
13 patients with normal lung function undergoing isolated hyperthermic cytostatic perfusion were submitted to high-frequency jet ventilation (HFJV; f = 150/min, inspiratory time 30%, FIO2 0.4) and conventional ventilation (CV; f = 12/min, PEEP + 4 cm H2O) respectively. Normoventilation required a minute ventilation of 6.4 +/- 1.1 l/min (paCO2 35.4 +/- 3.3 mmHg) with CV and 15.9 +/- 2.2 1/min (paCO2 39.0 +/- 4.3 mmHg) with HFJV. Mean airway pressure was significantly lower with HFJV (4.8 +/- 1.1 cm H2O) compared to CV (7.5 +/- 1.5 cm H2O). Arterial oxygenation, heart rate, pressures and resistances of systemic and pulmonary circulation, cardiac work and stroke indices, intrapulmonary shunting, and oxygen consumption showed equal values with both modes of ventilation. HFJV does not have any striking advantage over CV and therefore cannot be recommended for routine anaesthesia in abdominal surgery.
D000005:Abdomen / Q000601:surgery*; D010478:Chemotherapy, Cancer, Regional Perfusion; D003131:Combined Modality Therapy; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006979:Hyperthermia, Induced; D007866:Leg / Q000601:surgery; D008113:Liver Neoplasms / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000601:surgery; D011175:Positive-Pressure Respiration
Hämodynamische Befunde unter High Frequency Jet Ventilation bei grossen allgemeinchirurgischen Eingriffen.