Escherichia coli adherence to human transitional cell tumors: a simple research model of bacterial attachment to the lower urinary tract.
A simple model for assaying bacterial adherence to the urinary tract is presented. Cell suspensions of freshly excised transitional cell tumors were used as substrata for attachment of 3H-adenine-labeled Escherichia coli urine isolates. Quantitative radioactive counts were confirmed by microscopic observations in replicate assays of each condition tested. This model provided for species and organ specificity in studies of the bacterial adherence role in urinary tract infections.
D001422:Bacterial Adhesion; D002295:Carcinoma, Transitional Cell / Q000382:microbiology* / Q000503:physiopathology; D004926:Escherichia coli / Q000502:physiology*; D006384:Hemagglutination; D006801:Humans; D008954:Models, Biological; D001743:Urinary Bladder / Q000382:microbiology / Q000503:physiopathology; D001749:Urinary Bladder Neoplasms / Q000382:microbiology* / Q000503:physiopathology