title: [Multicentric reticulohistiocytosis. A case with unusual clinical, radiologic and ultrastructural aspects].
abstract: We are reporting a case of multicentric reticulo-histiocytosis which is exceptional because of its gravity and the diversity of the clinical lesions: huge subcutaneous nodules, bone destruction in the spine responsible for spondylolisthesis, pulmonary fibrosis, acute pericarditis, laryngeal compression requiring a permanent tracheostomy. From ultrastructural observations, various hypotheses to explain the intra-macrophagic accumulation of membrane granules and lipids are discussed.
mesh_terms: D001168:Arthritis / Q000209:etiology; D001859:Bone Neoplasms / Q000175:diagnosis*; D006801:Humans; D008055:Lipids / Q000032:analysis; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008206:Lymphatic Diseases / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D011658:Pulmonary Fibrosis / Q000209:etiology; D011859:Radiography; D012867:Skin / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000175:diagnosis*; D013125:Spinal Neoplasms / Q000175:diagnosis; D013168:Spondylolisthesis / Q000209:etiology; D013583:Synovial Membrane / Q000648:ultrastructure
chemical_list: D008055:Lipids
vernacular_title: Réticulo-histiocytose multicentrique. Un cas avec aspects cliniques, radiologiques et ultrastructuraux inhabituels.