The usefulness of the high voltage electron microscope in biomedical ultrastructure analysis.
We now have the tools to quantitate and correctly interpret the size, shape, and distribution of organelles in cells. It appears likely that the results will require some changes in some basic assumptions of ultrastructural cytology. This should also result in some new biochemical hypotheses about control of cell metabolism.
D002477:Cells / Q000648:ultrastructure; D006652:Histological Techniques; D008854:Microscopy, Electron / Q000592:standards*; D012106:Research; D013223:Statistics as Topic