In vitro and in vivo activities of ofloxacin against Mycobacterium leprae infection induced in mice.
Ofloxacin, a new quinolone, exhibits bactericidal activity against Mycobacterium leprae in mice, both in vivo and in vitro.
D000818:Animals; D005260:Female; D007917:Leprostatic Agents; D007918:Leprosy / Q000188:drug therapy*; D051379:Mice; D009166:Mycobacterium leprae / Q000187:drug effects*; D015242:Ofloxacin; D010078:Oxazines / Q000627:therapeutic use*
D007917:Leprostatic Agents; D010078:Oxazines; D015242:Ofloxacin