Improved grading of bone tumors with the monoclonal antibody Ki-67.
A total of 60 bone tumors and tumor-like lesions presenting various grades of malignancy were investigated immunohistologically with the monoclonal antibody Ki-67 directed against a cell proliferation-associated nuclear antigen. The results obtained agree well with those of flow cytometric and autoradiographic studies on similar tumor entities. The monoclonal antibody Ki-67 was found to be a handy and reliable tool for improved grading of bone tumors.
D000911:Antibodies, Monoclonal; D001859:Bone Neoplasms / Q000473:pathology*; D001842:Bone and Bones / Q000473:pathology; D002455:Cell Division; D006801:Humans; D007124:Immunoenzyme Techniques; D009367:Neoplasm Staging
D000911:Antibodies, Monoclonal