Pathophysiology of haemorrhagic shock.
Following massive blood loss a number of compensatory mechanisms are activated which are remarkably successful for a limited period. Ultimately the functions of many organs are affected, leading to a vicious circle of impaired cardiac performance and oxygen delivery. The only therapeutic manoeuvre of proven benefit in man is early restoration of circulating volume.
D000818:Animals; D001794:Blood Pressure; D001810:Blood Volume; D006706:Homeostasis; D006801:Humans; D008833:Microcirculation / Q000503:physiopathology; D012771:Shock, Hemorrhagic / Q000503:physiopathology* / Q000628:therapy; D013152:Splanchnic Circulation