title: [Genetic analysis of mitochondrial rho-mutability in Saccharomyces. IV. Relation between spontaneous rho-mutability and mitotic stability in disomic Saccharomyces cerevisiae].
abstract: In the yeast Saccharomyces cerevisiae the disomy for chromosome XIV resembles the previously described disomy for chromosome IV in that it leads to a significant decrease in spontaneous rho- mutability. The nuclear srm1 mutation, reducing spontaneous rho- mutability, diminishes significantly the mitotic disome stability. So, the mechanisms of spontaneous rho- mutagenesis and mitotic disome stability seem to compete for the function affected by the srm1 mutation.
mesh_terms: D004271:DNA, Fungal / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D005800:Genes, Fungal; D008938:Mitosis; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D004272:DNA, Mitochondrial
vernacular_title: Geneticheskiĭ analiz mitokhondrial'noĭ rho-mutabil'nosti u drozhzheĭ sakharomitsetov. Soobshchenie IV. O sviazi mezhdu spontannoĭ rho-mutabil'nost'iu i mitoticheskoĭ stabil'nost'iu disomikov u drozhzheĭ Saccharomyces cerevisiae.