Stimulus control of anticipatory nausea in cancer chemotherapy.
A single subject ABA design was used to evaluate the effect of a stimulus manipulation on anticipatory nausea. A lemon solution was orally administered to a 61-year-old female oncology patient in order to mask taste sensations thought to function as a conditioned stimulus eliciting anticipatory symptoms during chemotherapy. A decrease in anticipatory symptoms was observed with the introduction of the taste masking agent and was maintained following withdrawal of the agent.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy; D002746:Chlorpromazine / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003214:Conditioning, Classical; D003520:Cyclophosphamide / Q000009:adverse effects; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects; D008875:Middle Aged; D009325:Nausea / Q000209:etiology / Q000628:therapy*; D010470:Perceptual Masking; D013649:Taste
D003520:Cyclophosphamide; D005472:Fluorouracil; D002746:Chlorpromazine; D008727:Methotrexate