Role of intestinal flora in metabolism of agrochemicals conjugated with glutathione.
Intestinal processes which mediate the metabolic fate of glutathione conjugates of xenobiotics are reviewed. The role of the intestinal microflora in the metabolism of premercapturic acid pathway metabolites is discussed. The possible significance of mercapturic acid pathway metabolite catabolism in the bioaccumulation of methylthio-containing residues in the environment is presented.
D000821:Animal Feed / Q000032:analysis; D000818:Animals; D001711:Biotransformation; D005503:Food Additives / Q000378:metabolism*; D005978:Glutathione / Q000378:metabolism*; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism*; D007422:Intestines / Q000382:microbiology; D010575:Pesticides / Q000378:metabolism*
D005503:Food Additives; D010575:Pesticides; D005978:Glutathione