title: Cerebral spinal fluid recovery of lidocaine and bupivacaine following respiratory arrest subsequent to retrobulbar block.
abstract: A 75-year-old man experienced a self-limited respiratory arrest following a retrobulbar injection. The injection was a mixture of bupivacaine and lidocaine. Forty-five minutes after the injection, quantities of both drugs were recovered from the patient's cerebral spinal fluid (CSF) obtained via a lumbar puncture. Theoretical evidence is presented to show that the drug levels obtained resulted from a direct intrathecal injection.
mesh_terms: D000368:Aged; D000772:Anesthesia, Local; D002045:Bupivacaine / Q000008:administration & dosage / Q000009:adverse effects* / Q000134:cerebrospinal fluid* / Q000378:metabolism; D005123:Eye; D006801:Humans; D007267:Injections; D007700:Kinetics; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects / Q000134:cerebrospinal fluid*; D008297:Male; D012131:Respiratory Insufficiency / Q000139:chemically induced*
chemical_list: D008012:Lidocaine; D002045:Bupivacaine