Genetic suppression of a temperature-sensitive groES mutation by an altered subunit of RNA polymerase of Escherichia coli K-12.
Temperature-resistant suppressor mutants were isolated from Escherichia coli mutant strain groES131(Ts). Phage P1-mediated transduction and a two-dimensional gel electrophoretic analysis of cellular proteins indicated that these suppressor mutants carry an additional mutation in either the groEL gene or the rpoA gene.
D012321:DNA-Directed RNA Polymerases / Q000235:genetics* / Q000302:isolation & purification; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics* / Q000254:growth & development; D005796:Genes; D005798:Genes, Bacterial; D005838:Genotype; D046911:Macromolecular Substances; D009154:Mutation; D013489:Suppression, Genetic; D013696:Temperature
D046911:Macromolecular Substances; D012321:DNA-Directed RNA Polymerases