Levobunolol compared with timolol for the control of elevated intraocular pressure.
Two concentrations of levobunolol (0.5% and 1%) and one concentration of timolol (0.5%) were evaluated for the control of elevated intraocular pressure (IOP) in a double-masked, randomized study. Fifty-one patients received one of the three study treatments in both eyes bid for one year. Both drugs were equally effective in reducing IOP: The overall reduction in mean IOP was slightly more than 9 mm Hg in all three treatment groups. Levobunolol was as safe and effective as timolol for the long-term control of elevated IOP.
D002986:Clinical Trials as Topic; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D002040:Levobunolol / Q000627:therapeutic use*; D009798:Ocular Hypertension / Q000188:drug therapy; D013999:Timolol / Q000627:therapeutic use*
D013999:Timolol; D002040:Levobunolol