Schumanniofoside, the antisnake venom principle from the stem bark of Schumanniophyton magnificum Harms.
The methanol extract of the stem bark of Schumanniophyton magnificum and schumanniofoside, a chromone alkaloidal glycoside isolated from it, reduced the lethal effect of black cobra (Naja melanoleuca) venom in mice. This effect is greatest when the venom is mixed and incubated with the extract or schumanniofoside. It is thought that the mode of action is by oxidative inactivation of the venom.
D000818:Animals; D000997:Antivenins / Q000008:administration & dosage / Q000494:pharmacology*; D004546:Elapid Venoms / Q000037:antagonists & inhibitors*; D005260:Female; D006027:Glycosides / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology
D000997:Antivenins; D004546:Elapid Venoms; D006027:Glycosides; D010936:Plant Extracts; C051768:schumanniofoside