[Is it necessary to discontinue captopril before heart surgery?].
Interaction between kininase II and anaesthesia is not well described. Twenty two patients treated by kininase II for congestive heart failure are studied during anaesthesia for cardiovascular surgery. A first group of seventeen homogeneous hemodynamic data are reported. High cardiac index contrasts with severe clinical cardiac failure. A second group of inhomogeneous patients are separately described. Vasoconstrictor can be codified in the situation of low systemic resistance with high cardiac index. Preoperative treatment can be continued, under requirement of hemodynamic monitoring.
D000768:Anesthesia, General; D002216:Captopril / Q000008:administration & dosage*; D006348:Cardiac Surgical Procedures; D004329:Droperidol / Q000008:administration & dosage; D004347:Drug Interactions; D005283:Fentanyl / Q000008:administration & dosage; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D008991:Monitoring, Physiologic; D009609:Nitrous Oxide / Q000008:administration & dosage; D010197:Pancuronium / Q000008:administration & dosage; D011229:Preanesthetic Medication
D002216:Captopril; D010197:Pancuronium; D009609:Nitrous Oxide; D004329:Droperidol; D005283:Fentanyl
Faut-il arrêter le captopril avant l'opération en chirurgie cardiaque?