title: [Carbon band implants in animal experiments. Light and transmission electron microscopy studies of biocompatibility].
abstract: Part of the patella ligament was resected in rabbits and replaced by carbon fibre implants. After 1, 2, 3, 6 weeks, 3 and 12 months carbon implants with surrounding tissues as well as iliac lymph nodes were removed and examined by light- and transmission electron microscopy. Of special interest were the questions whether the carbon fibre implant, will be removed by phagocytosis and substituted by a new ligament or a adequate repair tissue? Our light- and transmission electron microscopic studies give no indication of successful removal of carbon fibres by phagocytosis. The carbon fibre implant was surrounded by dense connective tissue like a scar. In deep layers of the carbon implant was no vital dense or regular connective tissue, even not after 3 and 12 months. There is no replacement of the carbon fibre implant by a new ligament or tendon but a persistent foreign body reaction. With regard to these results it is very doubtful if good late results with ligament and tendon replacement by carbon fibre implants can be expected in patients.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002244:Carbon; D000077482:Carbon Fiber; D002921:Cicatrix / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology; D005549:Foreign-Body Reaction / Q000473:pathology; D008023:Ligaments, Articular / Q000473:pathology / Q000601:surgery*; D008854:Microscopy, Electron; D010587:Phagocytosis; D019736:Prostheses and Implants; D011817:Rabbits; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D000077482:Carbon Fiber; D002244:Carbon
vernacular_title: Carbonband-Implantate im Tierexperiment. Licht- und transmissions-elektronenmikroskopische Untersuchungen zur Biokompatibilität.