title: [A controlled double-blind trial of the possibilities of using nalbuphine in anesthesia in major surgical interventions on the upper abdomen].
abstract: A controlled, double-blind assessment of nalbuphine 0.3 mg kg-1 as an analgesic component of anaesthesia was made in 40 patients undergoing major upper abdominal surgery. The unpremedicated patients received thiopentone, alcuronium, nitrous oxide and oxygen, and either nalbuphine or saline. Enflurane was used to suppress autonomic nervous responses to surgery. Nalbuphine 0.3 mg kg-1 failed to influence the course of anaesthesia or the onset of post-operative pain, and produced no side-effects.
mesh_terms: D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D002763:Cholecystectomy; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004386:Duodenum / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009019:Morphinans; D009266:Nalbuphine; D013270:Stomach / Q000601:surgery*
chemical_list: D009019:Morphinans; D009266:Nalbuphine
vernacular_title: Ein kontrollierter Doppelblindversuch über die Einsatzmöglichkeiten von Nalbuphin in der Anaesthesie bei grösseren operativen Eingriffen im oberen Abdomen.