Coexistence of immunoreactivity for melanin-concentrating hormone and alpha-melanocyte-stimulating hormone in the hypothalamus of the rat.
Coexistence of immunoreactivity for melanin-concentrating hormone (MCH) and alpha-melanocyte-stimulating hormone (alpha-MSH) within rat hypothalamic neurons has been examined by the unlabeled antibody enzyme method. Neurons exhibiting both MCH- and alpha-MSH-like immunoreactivities were found in the dorsolateral hypothalamus, whereas no MCH-like immunoreactive perikarya were seen in the arcuate nucleus, where some neurons were stained with alpha-MSH antiserum. There seem to be two distinct alpha-MSH-like immunoreactive neurons in the rat hypothalamus, one exhibiting coexistence with MCH-like immunoreactivity and the other not showing any cross-reaction with MCH antiserum.
D000818:Animals; D007028:Hypothalamic Hormones; D007031:Hypothalamus / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D008297:Male; D008543:Melanins / Q000378:metabolism*; D009074:Melanocyte-Stimulating Hormones / Q000378:metabolism*; D010907:Pituitary Hormones / Q000378:metabolism*; D011333:Pro-Opiomelanocortin / Q000378:metabolism; D051381:Rats
D007028:Hypothalamic Hormones; D008543:Melanins; D010907:Pituitary Hormones; D011333:Pro-Opiomelanocortin; C019463:melanin-concentrating hormone; D009074:Melanocyte-Stimulating Hormones