[Local recurrence of mediastinal non-Hodgkin lymphomas in childhood].
Local relapses in mediastinal non-Hodgkin's lymphomas in childhood are rare. Of the 15 children treated in our hospital during the last 11 years, 2 had early local or pleural relapses. At presentation both had extensive pleural effusions, and after completion of induction therapy still some fluid in the pleural space was present. A local irradiation was not performed initially. Be review of the literature for risks and benefit of local irradiation in mediastinal non-Hodgkin's lymphoma, local irradiation in children receiving aggressive chemotherapy should only be considered in few patients; preferentially in those, with incomplete disappearance of the mediastinal tumor or, as we may conclude from our patients, incomplete disappearance of pleural effusion.
D000293:Adolescent; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D010997:Pleural Neoplasms / Q000175:diagnosis; D012306:Risk; D014057:Tomography, X-Ray Computed
Lokale Rezidive bei mediastinalen Non-Hodgkin-Lymphomen im Kindesalter.