title: Clinical experience with ofloxacin (DL 8280) in the therapy of various infections: preliminary report.
abstract: Thirteen hospitalized patients with various infections, five with typhoid fever, two with gastroenteritis, four with respiratory tract infection and two with biliary tract infection, were treated with ofloxacin at a daily dosage ranging between 600 and 900 mg orally. 12 patients completely recovered from the infection, and the pathogens were eradicated. Treatment failed in one patient suffering from respiratory tract infection. No side effects were recorded. In these cases ofloxacin can be considered as a safe and effective antimicrobial agent.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D002761:Cholangitis / Q000188:drug therapy; D002986:Clinical Trials as Topic; D005260:Female; D005759:Gastroenteritis / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin; D010078:Oxazines / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000188:drug therapy; D014435:Typhoid Fever / Q000188:drug therapy
chemical_list: D000890:Anti-Infective Agents; D010078:Oxazines; D015242:Ofloxacin