Linkage of Pep-2 and Apk on mouse chromosome 10.
An ethylnitrosourea (ENU)-induced electrophoretic variant of mouse PEP-2, a tripeptidase, has been used to determine the location of the structural gene on chromosome 10. Gene order and recombination frequencies were estimated as Apk-21.8 +/- 3.9%-Pep-2-3.7 +/- 2.1%-Sl. Methods for rapid determination of Apk and Pep-2 alleles by cellulose acetate electrophoresis and a valuable linkage testing stock carrying the unique Apkm and Pep-2b alleles are described.
D000135:Acid Phosphatase / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D005038:Ethylnitrosourea; D005260:Female; D008040:Genetic Linkage; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009154:Mutation; D010447:Peptide Hydrolases / Q000235:genetics*
D000135:Acid Phosphatase; D010447:Peptide Hydrolases; D005038:Ethylnitrosourea