title: The role of essential fatty acids in alcohol dependence and tissue damage.
abstract: Evidence for the role of essential fatty acids in alcohol dependence is reviewed. If alcohol-induced tissue damage is associated with impaired fatty acid and phospholipid metabolism, supplements of essential fatty acids might be beneficial in the treatment of alcoholics. The evidence for this effect is examined.
mesh_terms: D000328:Adult; D000367:Age Factors; D000437:Alcoholism / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D001921:Brain / Q000378:metabolism / Q000503:physiopathology*; D002986:Clinical Trials as Topic; D003071:Cognition; D003975:Diazepam / Q000627:therapeutic use; D004311:Double-Blind Method; D004910:Erythrocyte Membrane / Q000378:metabolism; D000431:Ethanol / Q000009:adverse effects*; D005228:Fatty Acids, Essential / Q000378:metabolism / Q000627:therapeutic use*; D005231:Fatty Acids, Unsaturated / Q000627:therapeutic use*; D006801:Humans; D008041:Linoleic Acids; D008104:Liver Cirrhosis, Alcoholic / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D031665:Oenothera biennis; D010743:Phospholipids / Q000097:blood / Q000378:metabolism; D010938:Plant Oils; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D017965:gamma-Linolenic Acid
chemical_list: D005228:Fatty Acids, Essential; D005231:Fatty Acids, Unsaturated; D008041:Linoleic Acids; D010743:Phospholipids; D010938:Plant Oils; D000431:Ethanol; C028498:evening primrose oil; D017965:gamma-Linolenic Acid; D003975:Diazepam