title: Clinical usefulness of the Vaughan Williams classification system.
abstract: The clinical usefulness of the Vaughan Williams classification scheme is limited by the complexity of the mechanisms of arrhythmia formation in man, which offer multiple potential sites for intervention. The properties of antiarrhythmic drugs may be considerably altered in abnormal myocardium. Despite these limitations, however, the classification provides a valuable conceptual framework for the understanding of the clinical electrophysiological properties of antiarrhythmic drugs and for their use.
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000145:classification* / Q000494:pharmacology / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D006801:Humans; D008954:Models, Biological
chemical_list: D000889:Anti-Arrhythmia Agents