title: Metallothionein.
abstract: Early research on metallothionein centered on aspects related to a detoxification role. As our understanding of the complex endocrine control that regulates metallothionein gene expression increases, a wider appreciation of a functional role(s) is emerging. Medical implications of control of metallothionein turnover include diagnosis of specific diseases and regulation of its expression as a host defense component.
mesh_terms: D001665:Binding Sites; D001692:Biological Transport; D002352:Carrier Proteins / Q000378:metabolism; D005609:Free Radicals; D005786:Gene Expression Regulation / Q000187:drug effects; D006728:Hormones / Q000494:pharmacology; D006801:Humans; D008658:Inactivation, Metabolic; D007408:Intestinal Absorption; D008247:Lysosomes / Q000502:physiology; D007706:Menkes Kinky Hair Syndrome / Q000378:metabolism; D008668:Metallothionein / Q000378:metabolism / Q000502:physiology; D008670:Metals / Q000378:metabolism / Q000506:poisoning; D011487:Protein Conformation
chemical_list: D002352:Carrier Proteins; D005609:Free Radicals; D006728:Hormones; D008670:Metals; D008668:Metallothionein