Granulocyte chemotaxis in acute human Plasmodium falciparum malaria.
The non-lymphoid elements of the peripheral leucocyte pool were examined in the present study to determine their response to chemotactic stimulation. Our results indicate that granulocytes are effectively mobilized during malaria infections and are not deactivated by complement-derived chemotactic factors. These findings provide further evidence for the restriction of immunosuppression to some specific T and B-cell related functions only.
D000208:Acute Disease; D000328:Adult; D002634:Chemotaxis, Leukocyte; D003167:Complement Activation / Q000187:drug effects; D004731:Endotoxins / Q000494:pharmacology; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D008288:Malaria / Q000276:immunology*; D008875:Middle Aged; D010963:Plasmodium falciparum
D004731:Endotoxins