Sciatic nerve in experimental leprosy.
Swiss albino mice were inoculated with Mycobacterium leprae obtained from untreated lepromatous patients. Histopathological study of sciatic nerves showed no abnormality. However a few free acid fast bacilli (AFB) were detected in the sciatic nerves taken from the inoculated limbs during the early stages of infection, suggesting the nerve-fibre route of travel as seen in humans in experimental leprosy, too.
D000818:Animals; D006801:Humans; D007918:Leprosy / Q000473:pathology*; D051379:Mice; D008815:Mice, Inbred Strains; D009166:Mycobacterium leprae / Q000302:isolation & purification; D012584:Sciatic Nerve / Q000382:microbiology / Q000473:pathology*