title: Roles of the Pribnow box in positive regulation of the ompC and ompF genes in Escherichia coli.
abstract: The roles of the first base of the Pribnow box in positive regulation of the ompC and ompF genes were studied. G- and A-to-T substitutions of the first base of the ompC and ompF Pribnow boxes, respectively, resulted in a high-level functioning of the promoters in the ompR background. The level was further enhanced significantly in the ompR+ background. The effects of other substitutions were also studied. Based on these observations, the roles of the Pribnow box in the positive regulation are discussed.
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001483:Base Sequence; D004926:Escherichia coli / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D005809:Genes, Regulator; D010957:Plasmids; D011401:Promoter Regions, Genetic; D013045:Species Specificity
chemical_list: D001425:Bacterial Outer Membrane Proteins