Search for teratogenic risks with the aid of malformation registries.
A summary is given of experiences in the use of the Swedish registries of birth defects for causal epidemiological studies. Case-control studies and cohort studies are described and exemplified. The application of case-control techniques to cohorts of women selected for probable or possible exposure is also described. The importance of using large-scale registry studies in the search for common but low-risk teratogens is stressed.
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology; D002971:Cleft Lip / Q000209:etiology; D002972:Cleft Palate / Q000209:etiology; D003199:Computer Systems; D000013:Congenital Abnormalities / Q000453:epidemiology* / Q000209:etiology; D004065:Digestive System Abnormalities; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000009:adverse effects; D005260:Female; D006801:Humans; D008872:Microwaves / Q000009:adverse effects; D009436:Neural Tube Defects / Q000139:chemically induced; D010969:Plastics / Q000009:adverse effects; D011247:Pregnancy; D011846:Radio Waves / Q000009:adverse effects; D012042:Registries; D012306:Risk; D012907:Smoking; D013548:Sweden
D004785:Environmental Pollutants; D010969:Plastics