A rat spermatocyte surface protein is involved in adhesion of pachytene spermatocytes to Sertoli cells in vitro.
Immunochemical approaches were used in trying to identify rat spermatocyte molecules involved in the adhesion to Sertoli cells in coculture. The results show that a surface protein of 80,000 apparent molecular weight strongly inhibits spermatocyte adhesion, suggesting it to be the germ cell surface component involved in the recognition of Sertoli cells.
D000818:Animals; D000954:Antigens, Surface; D002448:Cell Adhesion; D002450:Cell Communication; D066298:In Vitro Techniques; D008297:Male; D008565:Membrane Proteins / Q000276:immunology / Q000502:physiology*; D008970:Molecular Weight; D051381:Rats; D012708:Sertoli Cells / Q000166:cytology / Q000276:immunology / Q000502:physiology*; D013090:Spermatocytes / Q000166:cytology / Q000276:immunology / Q000502:physiology*
D000954:Antigens, Surface; D008565:Membrane Proteins