Cross reactivity of anti-epithelial membrane antigen monoclonal for reactive and neoplastic glial cells.
An anti-epithelial membrane antigen monoclonal (Clone E29) was used as part of a panel of antisera in the investigation of primary CNS and metastatic tumours. In contrast to others, definite and often strongly positive cross-reactivity has been demonstrated on glial cells. The material consisted of fourteen astrocytomas, two ependymomas, six cerebral metastases and two cases of gliosis.
D000911:Antibodies, Monoclonal; D000941:Antigens / Q000032:analysis*; D001254:Astrocytoma / Q000032:analysis; D001932:Brain Neoplasms / Q000032:analysis*; D002277:Carcinoma / Q000032:analysis; D003429:Cross Reactions; D004806:Ependymoma / Q000032:analysis; D005911:Gliosis / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D008565:Membrane Proteins / Q000032:analysis*; D018396:Mucin-1; D009457:Neuroglia / Q000032:analysis
D000911:Antibodies, Monoclonal; D000941:Antigens; D008565:Membrane Proteins; D018396:Mucin-1