Management of urgent hypertension: a comparison of oral treatment regimens in the emergency department.
Urgent hypertension is defined by severe elevations of blood pressure without associated end-organ damage. The use of parenteral agents for this entity entails intensive monitoring and the potential for significant hemodynamic complications. Therefore, various oral regimens have been studied. Herein described are mechanisms of action, pharmacokinetics, clinical efficacy, and side effects of oral agents used in the treatment of urgent hypertension.
D000284:Administration, Oral; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002216:Captopril / Q000009:adverse effects / Q000627:therapeutic use; D003000:Clonidine / Q000009:adverse effects / Q000627:therapeutic use; D004334:Drug Administration Schedule; D004636:Emergency Service, Hospital; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007741:Labetalol / Q000009:adverse effects / Q000627:therapeutic use; D008914:Minoxidil / Q000008:administration & dosage / Q000627:therapeutic use; D009543:Nifedipine / Q000009:adverse effects / Q000627:therapeutic use; D011224:Prazosin / Q000008:administration & dosage / Q000627:therapeutic use
D000959:Antihypertensive Agents; D008914:Minoxidil; D002216:Captopril; D009543:Nifedipine; D003000:Clonidine; D007741:Labetalol; D011224:Prazosin