[Age-related characteristics of the effect of adrenomimetics and adrenoblockaders on the calcium and magnesium content of the rat myocardium].
The effects of noradrenaline (0.025 mg/kg), izadrin (0.1 mg/kg), adrenaline (0.025 mg/kg), ephedrine (5 mg/kg) phentolamine (5 mg/kg), dibenamine (5 mg/kg), anaprilin (1 mg/kg), alpheprol (1 mg/kg) on calcium and magnesium contents in the myocardium of growing rats (7 and 30 days, 3-5 months) were studied. During the animal development and growth the effects of adrenomimetics on calcium and magnesium metabolism decrease to a lesser degree than those of adrenoblockers. The data obtained indicate the enhancement of the regulatory factors and attenuation of the metabolic factors of the mechanism of adrenergic agents' action in the process of the postnatal development.
D000375:Aging / Q000187:drug effects* / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D005260:Female; D006128:Growth / Q000187:drug effects; D006321:Heart / Q000187:drug effects*; D008274:Magnesium / Q000378:metabolism*; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D013565:Sympatholytics / Q000494:pharmacology*; D013566:Sympathomimetics / Q000494:pharmacology*
D013565:Sympatholytics; D013566:Sympathomimetics; D008274:Magnesium; D002118:Calcium
Vozrastnye osobennosti vliianiia adrenomimetikov i adrenoblokatorov na soderzhanie kal'tsiia i magniia v miokarde krys.