title: [Giant hamartomatous nevus of undescribed complexity (development of an infiltrating malignant melanoma)].
abstract: A case is reported of complex hamartoma with the aspect of a giant pigmented nevus, localized in one of the lower extremities. Histological examination revealed the involvement of different embryonal layers in order to give rise to dissimilar types of nevi: flat pigmented nevus, intradermal cellular nevus, epidermal verrucous nevus, Jadassohn's sebaceous nevus; Hoffman-Zurhelle's superficial lipomatous nevus, and fibrous hamartoma of the manifested at infancy. This malformation and more specifically the nevus cells constitute the subsequent transformation into an infiltrating malignant blastoma (malignant melanoma).
mesh_terms: D000368:Aged; D005260:Female; D006222:Hamartoma / Q000151:congenital / Q000473:pathology*; D006801:Humans; D007636:Keratoacanthoma / Q000473:pathology; D008067:Lipoma / Q000473:pathology*; D008545:Melanoma / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009508:Nevus, Pigmented / Q000151:congenital / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology; D012878:Skin Neoplasms / Q000151:congenital / Q000473:pathology*
vernacular_title: Nevo hamartomatoso gigante de complejidad no descrita (desarrollo de un melanoma maligno infiltrante).