[Effect of morphine and pentazocine on emotional-behavioral and hemodynamic nociceptive reactions].
Pentazocine (5-15 mg/kg) fails to change the period of latency in the rat tail-flick reaction at thermic stimulation but suppresses to the same extent as morphine (5 mg/kg) the emotional-pain response and enhances the reactions of arterial blood pressure during mechanical stimulation. Both prazosin and naloxone (1 mg/kg) abolished the activating effect of pentazocine on the arterial blood pressure changes produced by nociceptive stimulation.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001794:Blood Pressure / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004644:Emotions / Q000187:drug effects*; D009020:Morphine / Q000494:pharmacology*; D009270:Naloxone / Q000494:pharmacology; D009619:Nociceptors / Q000187:drug effects*; D010423:Pentazocine / Q000494:pharmacology*; D051381:Rats; D011930:Reaction Time / Q000187:drug effects; D014828:Vocalization, Animal / Q000187:drug effects
D009270:Naloxone; D009020:Morphine; D010423:Pentazocine
Vliianie morfina i pentazotsina na émotsional'no-povedencheskie i gemodinamicheskie notsitseptivnye reaktsii.