Perinatal management and outcome of fetal ventriculomegaly.
In 20 consecutive cases of fetal ventriculomegaly, diagnosed by antenatal ultrasound examination, hydrocephalus was isolated in six patients (30%) and was associated with other anomalies in 14 (70%). There were no false positive diagnoses of fetal ventriculomegaly in this series. Fetal structural and/or chromosome abnormalities were diagnosed antenatally in 11 of the 14 patients (78.5%) with postnatally documented anomalies. In ten patients (50%), isolated fetal ventriculomegaly or ventriculomegaly associated with spina bifida was diagnosed antenatally, and the perinatal management consisted of frequent ultrasound examinations, weekly fetal biophysical profiles, and delivery by cesarean section after documenting fetal lung maturity. Ventriculo-amniotic shunt placement was not part of the management. The outcomes were induced abortion, four patients (20%); intrapartum death, two patients (10%); postnatal death, five patients (25%); and currently alive, nine patients (45%).
D000015:Abnormalities, Multiple / Q000175:diagnosis; D002552:Cerebral Ventricles / Q000473:pathology*; D002869:Chromosome Aberrations / Q000175:diagnosis; D025063:Chromosome Disorders; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D006849:Hydrocephalus / Q000175:diagnosis; D006984:Hypertrophy / Q000175:diagnosis; D011247:Pregnancy; D011296:Prenatal Diagnosis; D016136:Spina Bifida Occulta / Q000175:diagnosis; D014463:Ultrasonography