title: [Effects of treatment with Macronil on the viral population of the pharynx in 0- to 5-year-old children with acute respiratory infections].
abstract: Macronil (a concentrated proteic extract from mackerel) associated to usual therapeutics (antibiotics, antipyretics, vitamins) in children aged 0-5 years, with acute respiratory infections led to a reduction of the viral pharyngeal population as detected by immunofluorescence (IF) technics. The IF positivity rate in children receiving Macronil was half as high as in controls receiving only the usual therapeutics. At the same time, the number of virus species detected in the pharynx of Macronil treated children was lower than in controls in which the viral pharyngeal population was not influenced in any way by the administered therapeutics without Macronil.
mesh_terms: D000208:Acute Disease; D000998:Antiviral Agents; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005455:Fluorescent Antibody Technique; D006801:Humans; D007223:Infant; D010614:Pharynx / Q000382:microbiology*; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D014020:Tissue Extracts / Q000627:therapeutic use*; D014777:Virus Diseases / Q000188:drug therapy*
chemical_list: D000998:Antiviral Agents; D014020:Tissue Extracts; C052285:macronil
vernacular_title: Etude des effets du traitement au Macronil sur la population virale pharyngienne chez des enfants âgés de 0 à 5 ans, souffrant d'infections respiratoires aiguës.