[Hybridomas synthesizing monoclonal antibodies to Bordetella pertussis toxins].
Hybridomas synthetizing monoclonal antibodies (McAb) to B. pertussis toxin (BPT) and endotoxin, or lipopolysaccharide (LPS), were obtained. The specificity of McAb to BPT was confirmed in the leukocytosis-stimulating factor neutralization test. Two hybridomas synthetized McAb, seemingly active against the common determinant of BPT and LPS. The McAb of one hybridoma reacted with the crude extract of BPT.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification; D000918:Antibody Specificity; D000942:Antigens, Bacterial / Q000276:immunology; D006825:Hybridomas / Q000276:immunology*; D007114:Immunization; D007158:Immunologic Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D037342:Pertussis Toxin; D010566:Virulence Factors, Bordetella / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D010566:Virulence Factors, Bordetella; D037342:Pertussis Toxin
Gibridomy, sinteziruiuschchie monoklonal'nye antitela k nekotorym toksinam Bordetella pertussis.