[Features of the extracellular matrix of fibroadenomas and leaf-shaped tumors of the human breast (immunomorphologic study)].
Fibronectin and collagen I, III, IV, V distribution in preexisting and newly formed connective tissue of fibroadenomas and leaf-like human breast tumour was studied by the immunofluorescent method. Extracellular matrix of a newly formed connective tissue was characterized by the predominance of collagen type III, the presence of collagen type IV, a high content of fibronectin in a leaf-like tumour. Such characteristics of the extracellular matrix structure in benign tumours are interpreted as a manifestation of desmoplasia.
D000232:Adenofibroma / Q000378:metabolism*; D001943:Breast Neoplasms / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D005260:Female; D005353:Fibronectins / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D006801:Humans
D005353:Fibronectins; D003094:Collagen
Osobennosti ékstratselliuliarnogo matriksa fibroadenom i listovidnoĭ opukholi molochnykh zhelez cheloveka (immunomorfologicheskoe issledovanie).