title: Treatment of pseudopregnancy with bromocriptin, an ergot alkaloid.
abstract: One hundred and forty-two dogs with single or multiple pseudopregnancies were treated with bromocriptin at three different dose rates and once in combination with mobilerone. The treatments that scored best were 30 micrograms/kg bromocriptin for 16 days and 10 micrograms/kg bromocriptin for 10 days. Vomiting was a frequent side effect (about 20 per cent of cases) and was treated successfully with metoclopramide at a dosage of 0.5 mg/kg. Metoclopramide had no effect on the effectiveness of the bromocriptin.
mesh_terms: D000818:Animals; D001971:Bromocriptine / Q000009:adverse effects / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004359:Drug Therapy, Combination; D005260:Female; D007774:Lactation / Q000187:drug effects; D008787:Metoclopramide / Q000627:therapeutic use; D009277:Nandrolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D011247:Pregnancy; D011555:Pseudopregnancy / Q000188:drug therapy / Q000523:psychology / Q000662:veterinary*; D014839:Vomiting / Q000139:chemically induced
chemical_list: D001971:Bromocriptine; D009277:Nandrolone; C100075:mibolerone; D008787:Metoclopramide