Amoxapine-induced cognitive impairment in two patients.
Two patients are described in whom subtle cognitive impairments are associated with therapeutic doses of amoxapine. The implications of this observation for the management of depression, particularly in patients with coexisting dementing illnesses, are discussed.
D000368:Aged; D000369:Aged, 80 and over; D000657:Amoxapine / Q000009:adverse effects* / Q000627:therapeutic use; D003072:Cognition Disorders / Q000139:chemically induced*; D003704:Dementia / Q000150:complications; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy*; D003989:Dibenzoxazepines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male
D003989:Dibenzoxazepines; D000657:Amoxapine