Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation.
A new model for evaluating nonsteroidal anti-inflammatory drugs (NSAIDs) is described. In this model of postoperative inflammation, the anti-inflammatory activity of curcumin (diferuloyl methane) was investigated in comparison with phenylbutazone and placebo. Phenylbutazone and curcumin produced a better anti-inflammatory response than placebo.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D002396:Catechols / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003474:Curcumin / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010653:Phenylbutazone / Q000627:therapeutic use; D011183:Postoperative Complications / Q000188:drug therapy*; D011897:Random Allocation
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002396:Catechols; D010653:Phenylbutazone; D003474:Curcumin