The causes of tissue damage in toxoplasmic retinochoroiditis.
The pathogenetic mechanisms of tissue damage in toxoplasmic retinochoroiditis are complex and incompletely understood. They include invasion and parasitisation of retinal tissues by the Toxoplasma parasite and localised tissue damage by a complex associated immune response. Clinical and experimental studies which shed light upon our understanding of the disease process are reviewed and discussed with regard to current policies in treatment.
D000818:Animals; D002825:Chorioretinitis / Q000276:immunology / Q000469:parasitology* / Q000473:pathology; D006790:Host-Parasite Interactions; D006801:Humans; D051379:Mice; D012160:Retina / Q000469:parasitology / Q000473:pathology; D014122:Toxoplasma; D014126:Toxoplasmosis, Ocular / Q000276:immunology / Q000469:parasitology* / Q000473:pathology