Pre-infusion heart rates and laboratory-induced panic anxiety.
Resting and pre-infusion heart rates recorded in 66 panic disorder patients revealed no significant differences between panickers and nonpanickers. There was also no significant difference in pre-fusion heart rates between either lactate or isoproterenol panickers and placebo nonpanickers. There was neither a sensitizing nor a desensitizing effect of laboratory-induced panic attacks on subsequent pre-infusion heart rates.
D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000187:drug effects*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005239:Fear / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007262:Infusions, Intravenous; D007545:Isoproterenol / Q000494:pharmacology*; D007773:Lactates / Q000494:pharmacology*; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D010200:Panic / Q000187:drug effects*
D007773:Lactates; D019344:Lactic Acid; D007545:Isoproterenol