Substance P-like immunoreactivity in the retina and optic lobe of the squid.
The distribution of substance P-like immunoreactivity within the squid retina and brain was studied by immunofluorescence. Positive immunoreactivity was observed as a single layer of fibres in the retina. The retina was devoid of tyrosine-hydroxylase, serotonin, gamma-aminobutyric acid, cholecystokinin, neuropeptide Y, somatostatin, enkephalin and vasoactive intestinal peptide immunoreactivities. Substance P immunoreactivity was particularly abundant in the optic lobe. The optic lobe had a distinct layer of substance P fibres near the periphery. Immunoreactive cell bodies, fibres and varicosities were additionally present in various areas of the optic lobe. Substance P immunoreactivity in the other ganglia of the brain was restricted to a few scattered fibres.
D000818:Animals; D049832:Decapodiformes / Q000378:metabolism*; D005123:Eye / Q000378:metabolism*; D005455:Fluorescent Antibody Technique; D005724:Ganglia / Q000378:metabolism*; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides / Q000378:metabolism*; D012160:Retina / Q000378:metabolism; D014795:Visual Pathways / Q000378:metabolism
D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; C016116:substance P-like peptides