[Basal cell nevus syndrome. Apropos of 2 new cases].
Two cases affected by the nevoid basal cell carcinoma syndrome are reported herein with multiple basal cell carcinomas on exposed areas, with the previous appearance of pigmented macules on which a morphological transformation was shown with the presence of erythematous papules and plaques in a ring-like, formation made up of epitheliomatous pearls, giving the appearance of lesional polymorphism. The clinical pathological diagnosis of epithelioma basocellular is confirmed. In both patients, numerous pits on the hands and feet are shown without noticeable subjective symptoms; one of the biopsies reveals a carcinoma of basal cells in the epidermis underlying the pit. A detailed study is carried out on both families with the existence of different osseous anomalies, without finding cutaneous stigmas. The treatments carried out are checked bringing in our experience with the locally applied 5-FU. It is clearly obvious that UV light is a key factor in these two cases.
D000328:Adult; D001478:Basal Cell Nevus Syndrome / Q000473:pathology*; D001706:Biopsy; D002280:Basal Cell Carcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D007568:Jaw / Q000000981:diagnostic imaging; D008297:Male; D011859:Radiography
Síndrome del nevus basocelular. A propósito de dos nuevos casos.