Response to bronchodilators assessed by lung mechanics.
Abnormalities of compliance and functional residual capacity were shown in eight young children aged 2-8 years with asthma during an acute attack. In a randomised, placebo controlled study treatment with bronchodilator (salbutamol) was associated with a significant improvement in compliance and lessening of hyperinflation as shown by a reduction in functional residual capacity.
D000208:Acute Disease; D000420:Albuterol / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D005260:Female; D005652:Functional Residual Capacity; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008170:Lung Compliance / Q000187:drug effects; D008297:Male; D011897:Random Allocation
D000420:Albuterol