title: Current perspectives on septic shock.
abstract: Although septic shock may be initiated by invading microbes, it is the metabolic and immunologic host responses that determine the true pathophysiology of this common critical care illness. Currently, septic shock therapeutics emphasize empiric and symptomatic treatment. Biochemical elucidation of the septic process will ultimately result in specific interventions for this ominous intensive care syndrome.
mesh_terms: D002199:Capillary Permeability; D002648:Child; D003422:Critical Care; D004731:Endotoxins / Q000378:metabolism; D006801:Humans; D012128:Respiratory Distress Syndrome / Q000209:etiology; D012151:Resuscitation; D012772:Shock, Septic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
chemical_list: D004731:Endotoxins