Retinal vasculitis in Crohn's disease.
Although systemic vasculitis is a prominent part of the extraintestinal complications of Crohn's disease, the association of a retinal vasculitis with this chronic granulomatous disease of the gastrointestinal system is rare. We examined a 26-year-old woman with biopsy-proven Crohn's disease who developed a severe bilateral, obliterative retinal arteritis and phlebitis, leading to a marked loss of vision. Treatment with systemic corticosteroids and cyclophosphamide succeeded in halting progression of the disease.
D000328:Adult; D003092:Colitis / Q000150:complications; D003424:Crohn Disease / Q000150:complications*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D009887:Ophthalmoscopy; D011241:Prednisone / Q000627:therapeutic use; D012171:Retinal Vessels; D014463:Ultrasonography; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
D003520:Cyclophosphamide; D011241:Prednisone