[Relation between the probability of development of altitude-decompression disorders and the duration of pre-exposure to a hypobaric atmosphere].
Healthy volunteers, aged 21-47 years, were kept in an altitude chamber. Before decompression to a residual pressure of 293.3 GPa the test subjects were consecutively exposed to 1120 GPa for 2 hrs and then to 733.3 GPa for 24, 18 or 12 hrs. At 293.3 GPa the test subjects performed a moderate workload for 6 hrs. It has been concluded that prior to the use of a space suit with the working pressure 0.3 kgf/cm2 (293.3 GPa) the time of exposure to a hypobaric normoxic (29-30% O2) atmosphere with the total barometric pressure 733.3 GPa should not be less than 18 hrs and it should preferably be 24 hrs. In this situation decompression safety of 6-hr extravehicular activity can be predicted with a high probability.
D000222:Adaptation, Physiological; D000328:Adult; D000532:Altitude Sickness / Q000517:prevention & control*; D001274:Atmospheric Pressure; D003665:Decompression Sickness / Q000517:prevention & control*; D005676:Gravity Suits; D006801:Humans; D000860:Hypoxia / Q000517:prevention & control*; D008875:Middle Aged; D010100:Oxygen / Q000502:physiology*; D012119:Respiration; D013026:Space Flight; D013997:Time Factors
D010100:Oxygen
Veroiatnost' razvitiia vysotno-dekompressionnnykh rasstroĭstv v zavisimosti ot prodolzhitel'nosti predvaritel'nogo prebyvaniia v gipobaricheskoĭ atmosfere.