title: Anatomic and anesthetic considerations in experimental cardiopulmonary surgery in swine.
abstract: We have used immature commercial swine (13-25 kg) successfully in a variety of experimental cardiopulmonary surgical procedures in our laboratories since 1981. Multiple drug anesthetic protocols using barbiturates, narcotics, paralytic and antiarrhythmic agents have been employed in over 400 procedures per year. Complications, including fatal cardiac arrhythmias, have been greatly reduced by anesthetic protocols and surgical procedures developed through experience.
mesh_terms: D000075:Acepromazine; D000758:Anesthesia / Q000662:veterinary*; D000818:Animals; D001145:Arrhythmias, Cardiac; D001919:Bradycardia; D002315:Cardiopulmonary Bypass; D013504:Cardiovascular Surgical Procedures; D005260:Female; D005283:Fentanyl; D006221:Halothane; D016027:Heart Transplantation; D008297:Male; D010197:Pancuronium; D010424:Pentobarbital; D011013:Pneumonectomy; D013390:Succinylcholine; D013552:Swine / Q000601:surgery*; D013840:Thiamylal; D013874:Thiopental; D014693:Ventricular Fibrillation
chemical_list: D013840:Thiamylal; D000075:Acepromazine; D010424:Pentobarbital; D013390:Succinylcholine; D010197:Pancuronium; D013874:Thiopental; D005283:Fentanyl; D006221:Halothane