B-Z DNA conformational transition in 1:1 electrolytes: dependence upon counterion size.
We have studied the B-Z transition of poly[d(G-C)] in the presence of alkali metal, tetramethylammonium and tetraethylammonium chlorides at room temperature. The measured critical salt concentrations increase in the order Na, K, Rb, TMA, Cs and are in good agreement with the theoretical values predicted from a statistical-mechanical treatment of the transition.
D002586:Cesium / Q000494:pharmacology; D002712:Chlorides / Q000494:pharmacology; D004247:DNA; D004573:Electrolytes / Q000494:pharmacology*; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D011089:Polydeoxyribonucleotides; D011189:Potassium Chloride / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D012413:Rubidium / Q000494:pharmacology; D012965:Sodium Chloride / Q000494:pharmacology; D019789:Tetraethylammonium; D013757:Tetraethylammonium Compounds / Q000494:pharmacology
D002712:Chlorides; D004573:Electrolytes; D011089:Polydeoxyribonucleotides; D000644:Quaternary Ammonium Compounds; D013757:Tetraethylammonium Compounds; D002586:Cesium; C019530:poly(dC-dG); D012965:Sodium Chloride; D019789:Tetraethylammonium; D011189:Potassium Chloride; D004247:DNA; C028019:cesium chloride; C027917:tetramethylammonium; D012413:Rubidium; C032710:rubidium chloride