title: Reversed septal motion in right ventricular volume overload: false negative sign in the presence of increased septal thickness.
abstract: Paradoxical septal motion of the interventricular septum and right ventricular enlargement constitute diagnostic features of right ventricular volume overload. A diastolic septal displacement toward the left ventricle and its systolic normalization explain this phenomenon. A thick septum would, theoretically, impede such movement. One patient with a cardiac allograft and gross tricuspid regurgitation is described who, in the context of a rejection episode and in a very short interval, showed two septal motion patterns related to two different septal thicknesses. It is concluded that in a patient with large right ventricular dimension and increased septal thickness, lack of paradoxical septal motion does not rule out severe right ventricular volume overload.
mesh_terms: D000328:Adult; D004452:Echocardiography; D005188:False Negative Reactions; D006084:Graft Rejection / Q000187:drug effects; D006346:Heart Septum / Q000473:pathology / Q000503:physiopathology*; D016027:Heart Transplantation; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000209:etiology; D006352:Heart Ventricles / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009200:Myocardial Contraction; D011183:Postoperative Complications; D014261:Tricuspid Valve
chemical_list: D008775:Methylprednisolone