High-frequency ultrasound measurement of patch test reactions.
53 patients who produced 34 positive patch test reactions (+/- 15, +10, ++4, +++5) had their reactions read by a high-frequency pulsed ultrasonic (A-scan) dermal depth detector with a resolution of 0.05 mm. The positive reactions were compared with both random and regional controls. The machine could not differentiate between + or +/- reactions from the control readings. However, for 75% of ++ cases and 80% of +++ cases, a significant change was confirmed by the detector. It is concluded that the high-frequency ultrasound method is of little use in confirming or quantifying of positive patch test results.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003877:Dermatitis, Contact / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D012867:Skin / Q000473:pathology; D012882:Skin Tests; D014463:Ultrasonography