Nocardial endocarditis of an aortic valve prosthesis.
The organism responsible for endocarditis of a prosthetic aortic valve was identified as Nocardia asteroides. The patient was treated with intravenous amikacin (250 mg four times a day) and intravenous imipenem (1.5 g four times a day). The valve was replaced under this new antibiotic regimen. This is the first report of survival after prosthetic valve nocardiosis.
D000583:Amikacin / Q000627:therapeutic use; D001021:Aortic Valve / Q000601:surgery; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology*; D006350:Heart Valve Prosthesis; D006801:Humans; D015378:Imipenem; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000188:drug therapy / Q000209:etiology*; D009616:Nocardia asteroides; D011183:Postoperative Complications / Q000188:drug therapy*; D013845:Thienamycins / Q000627:therapeutic use
D013845:Thienamycins; D015378:Imipenem; D000583:Amikacin