Thymostimulin prophylaxis of postoperative infections in anergic patients.
The rate of postoperative infections is significantly increased in anergic patients. The authors evaluated prospectively, in a controlled, randomized and stratified study, the efficiency of thymostimulin in reducing postoperative infections in 42 such patients. Excluded were those who were malnourished in whom preoperative alimentation corrected the anergy. The incidence of infections was significantly (p less than 0.05) reduced in thymostimulin-treated patients (4.8% versus 28.6%).
D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000276:immunology* / Q000517:prevention & control; D002986:Clinical Trials as Topic; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects*; D007273:Injections, Intramuscular; D011183:Postoperative Complications / Q000276:immunology* / Q000517:prevention & control; D011446:Prospective Studies; D011897:Random Allocation; D013949:Thymus Extracts / Q000008:administration & dosage / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D013949:Thymus Extracts; C031407:thymostimulin