Vacuolar degeneration of the cochlea in young rats.
In the course of investigations of the post-natal development of the ear in Sprague-Dawley rats, a hitherto unrecorded degenerative process was seen in two animals (7-and-8-days old). The process was characterized by vacuolization of almost all the cellular elements of the cochlear tissues. The overall shape and size of the cochlear structures remained well preserved. The organ of Corti did not atrophy but its components were vacuolized, as well as the cells of other inner ear tissues, except for nuclei in the lower part of the modiolus.
D000375:Aging; D000818:Animals; D003051:Cochlea / Q000254:growth & development / Q000473:pathology*; D007759:Labyrinth Diseases / Q000473:pathology / Q000662:veterinary*; D051381:Rats; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000473:pathology*