Hyperkeratosis lenticularis perstans (Flegel's disease). A light and electron microscopic study of involved and uninvolved epidermis.
Lesional as well as uninvolved skin were studied by light and electron microscopy in 1 case of hyperkeratosis lenticularis perstans (Flegel's disease). The main ultrastructural finding was a morphological alteration of lamellar (Odland) bodies. A review of the literature on the ultrastructure of Flegel's disease is made, and the significance of the ultrastructural findings is briefly discussed.
D004817:Epidermis / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007642:Keratosis / Q000473:pathology*; D008854:Microscopy, Electron; D008875:Middle Aged