title: Novel reactions of 5-bromouracil derivatives with active methylene compounds.
abstract: 5-Bromouracil derivatives (1) reacted with carbanions at room temperature to give 6-substituted uracils (6), 2,4-diazabicyclo[4,1,0] heptanes (8) and 2,4-diazabicyclo[4,3,0]nonane derivative (9), which depend largely upon the structure of the active methylene compounds employed for the generation of carbanions.
mesh_terms: D000473:Alkanes; D001976:Bromouracil / Q000031:analogs & derivatives*; D055598:Chemical Phenomena; D002621:Chemistry; D007202:Indicators and Reagents; D013329:Structure-Activity Relationship
chemical_list: D000473:Alkanes; D007202:Indicators and Reagents; D001976:Bromouracil