Corticotropin-releasing factor mRNA is expressed in the inferior olives of rodents and primates.
Immunohistochemical studies have suggested that corticotropin-releasing factor (CRF) was a transmitter of the olivocerebellar projection. We used in situ hybridization histochemistry with a 35S-labeled oligodeoxyribonucleotide probe for CRF mRNA to show that inferior olivary neurons of rats, baboons, and humans synthesize CRF.
D000328:Adult; D000368:Aged; D000818:Animals; D001345:Autoradiography; D002531:Cerebellum / Q000032:analysis; D003346:Corticotropin-Releasing Hormone / Q000032:analysis / Q000235:genetics*; D006651:Histocytochemistry; D006801:Humans; D007158:Immunologic Techniques; D008297:Male; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D009847:Olivary Nucleus / Q000032:analysis*; D010215:Papio; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D012333:RNA, Messenger; D003346:Corticotropin-Releasing Hormone