Ultrasonic study of in vivo kinetic characteristics of human tissues.
A method is described for quantifying tissue movement in vivo from the computation of correlation coefficient between pairs of A-scans with appropriate time separation. The method yields quantifiable and repeatable secondary patterns of soft tissue movement in response to primary cardiac movement in a given subject, shows consistently different results as between normal livers and a variety of abdominal tumours, and is sensitive to either progress or therapeutically-induced regression of malignant disease. While the results reported here have been obtained using somewhat simple and crude equipment, the method is well suited to implementation on a commercial real-time scanner.
D000008:Abdominal Neoplasms / Q000503:physiopathology*; D006801:Humans; D007700:Kinetics; D008099:Liver / Q000033:anatomy & histology / Q000502:physiology* / Q000503:physiopathology; D008113:Liver Neoplasms / Q000473:pathology / Q000503:physiopathology; D008207:Lymphatic Metastasis / Q000503:physiopathology; D008223:Lymphoma / Q000473:pathology / Q000503:physiopathology; D009068:Movement; D014463:Ultrasonography / Q000379:methods