Roles of the Pribnow box in positive regulation of the ompC and ompF genes in Escherichia coli.
The roles of the first base of the Pribnow box in positive regulation of the ompC and ompF genes were studied. G- and A-to-T substitutions of the first base of the ompC and ompF Pribnow boxes, respectively, resulted in a high-level functioning of the promoters in the ompR background. The level was further enhanced significantly in the ompR+ background. The effects of other substitutions were also studied. Based on these observations, the roles of the Pribnow box in the positive regulation are discussed.
D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001483:Base Sequence; D004926:Escherichia coli / Q000235:genetics*; D005796:Genes; D005798:Genes, Bacterial; D005809:Genes, Regulator; D010957:Plasmids; D011401:Promoter Regions, Genetic; D013045:Species Specificity
D001425:Bacterial Outer Membrane Proteins