title: Clinical evaluation of the human basophil degranulation test in grass pollen allergic patients.
abstract: The reliability of the human basophil degranulation test (HBDT) is still in doubt. We took 20 orchard grass-sensitive patients and 20 non-sensitive subjects and compared the sensitivity of HBDT with skin test and RAST. Eighteen HBDTs were positive in skin test-positive patients. There was also a good correlation with the results of RAST.
mesh_terms: D001249:Asthma / Q000209:etiology / Q000276:immunology*; D001491:Basophils / Q000378:metabolism*; D003594:Cytoplasmic Granules / Q000378:metabolism; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007158:Immunologic Techniques; D006109:Poaceae; D011058:Pollen / Q000276:immunology*; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000209:etiology / Q000276:immunology*; D012882:Skin Tests
chemical_list: D007073:Immunoglobulin E