title: Radiophosphate visualization of the foreign body reaction to wear debris from total knee prosthesis.
abstract: Three patients with total knee arthroplasties, in which the tibial and patellar articulating surfaces consisted of a polyethylene-carbon fiber composite, demonstrated technetium-99m methylene diphosphonate (MDP) deposition in the intraarticular space, whereas, the gallium-67 citrate images were normal. This was shown to be due to a synovial giant cell foreign body reaction to particulate carbon fiber debris in one patient who required surgical revision of the prosthesis.
mesh_terms: D000328:Adult; D000368:Aged; D002244:Carbon; D000077482:Carbon Fiber; D005260:Female; D005549:Foreign-Body Reaction / Q000000981:diagnostic imaging*; D005710:Gallium Radioisotopes; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010969:Plastics; D011095:Polyethylenes; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate
chemical_list: D000077482:Carbon Fiber; D005710:Gallium Radioisotopes; D010969:Plastics; D011095:Polyethylenes; C037808:plastic, carbon fiber reinforced; D002244:Carbon; D013669:Technetium Tc 99m Medronate