Electron microscopic observations on dystrophic neurites in hamster brains infected with the 263K strain of scrapie.
Increased numbers of dystrophic neurites filled with inclusions were found in the brains of Syrian hamsters inoculated with scrapie but not in control animals. These neurites were seen as single entities or as clusters of up to three. The possibility that these structures are the beginning of the formation of plaques is discussed.
D000818:Animals; D001369:Axons / Q000648:ultrastructure*; D001921:Brain / Q000648:ultrastructure*; D001927:Brain Diseases / Q000473:pathology*; D006224:Cricetinae; D008854:Microscopy, Electron; D009410:Nerve Degeneration; D012608:Scrapie / Q000473:pathology*