title: N-terminal sequence of human leukocyte glycoprotein Mo1: conservation across species and homology to platelet IIb/IIIa.
abstract: Mo1 and gp160-gp93 are two surface membrane glycoprotein heterodimers present on granulocytes and monocytes derived from humans and guinea pigs, respectively. We purified both antigens and found that their alpha subunits had identical N-termini which were significantly homologous to the alpha subunit of the human adhesion platelet glycoprotein IIb/IIIa.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001792:Blood Platelets / Q000032:analysis*; D001798:Blood Proteins / Q000235:genetics*; D006023:Glycoproteins / Q000235:genetics*; D006168:Guinea Pigs; D006801:Humans; D007962:Leukocytes / Q000032:analysis*; D046911:Macromolecular Substances; D016177:Macrophage-1 Antigen; D051379:Mice; D010980:Platelet Membrane Glycoproteins / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
chemical_list: D001798:Blood Proteins; D006023:Glycoproteins; D046911:Macromolecular Substances; D016177:Macrophage-1 Antigen; D010980:Platelet Membrane Glycoproteins