title: The stability of 99Tcm-DTPA in an aerosol delivery system.
abstract: 99Tcm-DTPA is now widely used in aerosol nebulizers for routine ventilation lung scanning. The stability of a commercially available DTPA kit has been measured when used in an aerosol delivery system and compared with the stability when stored in the parent vial according to the manufacturer's instructions. No significant breakdown was measured up to 8 h after reconstitution in the parent vial and up to 3 h when used as an aerosol. Values of the half time of clearance of DTPA aerosols in a group of 23 patients are compared with values given in the literature.
mesh_terms: D000293:Adolescent; D000328:Adult; D000336:Aerosols; D000368:Aged; D004355:Drug Stability; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D004369:Pentetic Acid; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013667:Technetium; D016284:Technetium Tc 99m Pentetate
chemical_list: D000336:Aerosols; D013667:Technetium; D004369:Pentetic Acid; D016284:Technetium Tc 99m Pentetate