title: [Determination of C-reactive protein in serum using a fluorescence polarization immunoassay--comparison with the method of kinetic nephelometry (KNM)].
abstract: The determination of CRP in serum was performed by the fluorescence polarization immunoassay (FPIA) and the kinetic nephelometry (KNM). Both methods showed a good precision and accuracy. The investigation was carried out in 190 sera with a CRP concentration up to 49 mg/dl. The comparison of the two methods in 100 sera with a CRP concentration between 0.6 and 5 mg/dl showed a good correlation (correlation coefficient r = 0.9753). Close correlation (correlation coefficient r = 0.9947) was also found in 90 sera with a CRP concentration between 5 and 49 mg/dl. Discussion of the FPIA and KNM methods.
mesh_terms: D002097:C-Reactive Protein / Q000378:metabolism*; D002648:Child; D005454:Fluorescence Polarization; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D009391:Nephelometry and Turbidimetry / Q000379:methods*
chemical_list: D002097:C-Reactive Protein
vernacular_title: Bestimmung des C-reaktiven Proteins (CRP) im Serum mit dem Fluoreszenz-Polarisations-Immunoassay (FPIA)--Vergleich mit der Methode der kinetischen Nephelometrie (KNM).