[Micronucleus test as a short-term assay for detecting the potential carcinogenicity of different groups of chemical compounds].
Certain theoretical aspects of the method, the normal level of micronuclei in polychromatic erythrocytes of bone marrow cells in different animals species, the data obtained for the different types of chemical compounds are analyzed as well as the possibility of obtaining false-negative and false-positive results. This method is found to be very promising and needs further development in the near future.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000648:ultrastructure; D002273:Carcinogens; D002467:Cell Nucleus / Q000187:drug effects* / Q000648:ultrastructure; D004353:Drug Evaluation, Preclinical; D006801:Humans; D009152:Mutagenicity Tests
D002273:Carcinogens
Mikroiadernyĭ test kak kratkosrochnyĭ metod vyiavleniia potentsial'noĭ onkogennosti razlichnykh grupp khimicheskikh veshchestv.