The rate of biliary cholesterol secretion in high- and low-responding rhesus monkeys.
The rates of secretion of cholesterol in bile measured by an isotope ratio method were found similar in cholesterol-fed high- and low-responding rhesus monkeys. The results indicate that the failure on the part of the high-responders to increase proportionately the fecal excretion of neutral steroids to compensate for the higher absorption of cholesterol than the low-responders, as suggested earlier, is not due to a difference in the rate of biliary cholesterol secretion but must lie in some other aspect of cholesterol metabolism.
D000818:Animals; D001646:Bile / Q000378:metabolism*; D001835:Body Weight; D002250:Carbon Radioisotopes; D002784:Cholesterol / Q000378:metabolism*; D004032:Diet; D005243:Feces / Q000032:analysis; D008251:Macaca / Q000502:physiology*; D008253:Macaca mulatta / Q000502:physiology*; D008297:Male; D011865:Radioisotope Dilution Technique; D014316:Tritium
D002250:Carbon Radioisotopes; D014316:Tritium; D002784:Cholesterol