A new variant for whole pancreas grafting.
A new variant for whole pancreas grafting is described in which a segment of the duodenum and the spleen is included in the graft. The graft is placed extraperitoneally as in kidney transplantation. The exocrine drainage is with side-to-side anastomosis between duodenum and bladder. The spleen is irradiated to prevent the occurrence of GVHD, as is reported in splenic transplantation.
D000328:Adult; D000961:Antilymphocyte Serum; D003922:Diabetes Mellitus, Type 1 / Q000628:therapy*; D003928:Diabetic Nephropathies / Q000628:therapy; D004386:Duodenum / Q000637:transplantation*; D005260:Female; D005951:Glucose Tolerance Test; D006084:Graft Rejection; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D016035:Pancreas Transplantation; D013154:Spleen / Q000528:radiation effects / Q000637:transplantation*; D013601:T-Lymphocytes / Q000276:immunology
D000961:Antilymphocyte Serum