[Comparative effectiveness of levamisole and vaccine in the complex treatment of patients with brucellosis].
The clinical efficacy of levamisole was compared to that of vaccine in a controlled trial of a combined treatment performed in 311 patients with acute and subacute brucellosis. As compared with vaccine, levamisole appeared effective in the treatment of active forms of brucellosis both during the control of the active process and later in convalescence. The use of levamisole permitted reducing the percentage of the chronic forms of the disease. When administered for active forms of brucellosis vaccine did not turn superior to levamisole.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002004:Brucella Vaccine / Q000627:therapeutic use*; D002006:Brucellosis / Q000628:therapy*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
D002004:Brucella Vaccine; D007978:Levamisole
Sravnitel'naia éffektivnost' levamizola i vaktsiny v kompleksnom lechenii bol'nykh brutsellezom.