Constrictive pericarditis following coronary bypass reoperation. Fibrotic pericardium and a foreign body reaction.
A 65-year-old male patient underwent two bypass operations because of coronary artery disease. After the second operation he developed congestive heart failure with breathlessness, ankle swelling, hepatomegaly and poor exercise tolerance. Echocardiographic and haemodynamic findings were characteristic of constrictive pericarditis. Pericardiectomy was performed three months after the second operation. The retrosternal space was replaced with fibrotic, patchy hyalinic tissue, and the pericardium was thick and rigid. Histologically, the thickened pericardium showed dense fibrosis and foreign-body granulomas with large multinuclear giant cells and irregular crystals. This report indicates that foreign body reaction following coronary artery bypass operation may result in constrictive pericarditis with severe heart failure.
D000368:Aged; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D005355:Fibrosis; D005549:Foreign-Body Reaction / Q000209:etiology* / Q000473:pathology; D006099:Granuloma / Q000209:etiology; D006801:Humans; D008297:Male; D010494:Pericarditis, Constrictive / Q000209:etiology*; D010496:Pericardium / Q000473:pathology*; D011183:Postoperative Complications; D012086:Reoperation; D012501:Saphenous Vein / Q000637:transplantation