[Effect of luliberin on the secretion of luteinizing hormone as a function of the phase of menstrual cycle in intact and castrated female Papio hamadryas].
A comparative study of the LH time course in response to the administration of a standard dose of LH/RF was conducted in intact and castrated female papio hamadryas to find out the relationship between hypophyseal sensitivity to LH/RF action and the level of sex steroid hormones in the peripheral blood. A bioradioimmunoassay adapted for the monkey plasma was employed to measure the level of biologically active LH in the peripheral blood plasma. A stimulating effect of LH/RF on the hypophyseal LH secretion both in intact animals in different phases of the menstrual cycle and in gonadectomized females was established. The relationship between the nature of the LH time course and the level of sex steroid hormones in the peripheral blood plasma was shown; a prolonged high level of LH reciprocal secretion into the follicular phase occurred against a background of a high and constant estradiol/progesterone ratio, and LH one-type impulse release into the luteal phase and in castrated females occurred against a background of a low value of the ratio of these hormones.
D000818:Animals; D002369:Castration; D005260:Female; D005498:Follicular Phase; D007987:Gonadotropin-Releasing Hormone / Q000502:physiology*; D008183:Luteal Phase; D007986:Luteinizing Hormone / Q000378:metabolism*; D008597:Menstrual Cycle; D010215:Papio
D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone
Vliianie liuliberina na sekretsiiu liuteiniziruiushchego gormona v zavisimosti ot fazy menstrual'nogo tsikla u intaktnykh i kastrirovannykh samok pavianov gamadrilov.