[Chromosomal changes in patients with acute dysentery and their relation to immunologic shifts].
The correlation between the dynamics of the occurrence of the class of lymphocytes without chromosomal associations and with two associating acrocentric chromosomes (CL0 + 2) and the course of the disease, as well as the development of immunity in patients with acute dysentery, has been detected. The positive correlation between the occurrence of CL0 + 2 and cell-mediated immunity reactions presupposes the possibility of using this cytogenetic characteristic for evaluating the cell-mediated immunoreactivity of lymphocytes. No essential changes in the frequency of chromosomal aberrations in lymphocytes have been found to occur at all periods of observation.
D000208:Acute Disease; D000328:Adult; D000917:Antibody Formation; D002455:Cell Division; D002503:Centromere / Q000648:ultrastructure; D002869:Chromosome Aberrations; D004405:Dysentery, Bacillary / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D008875:Middle Aged; D012763:Shigella flexneri; D012764:Shigella sonnei; D013601:T-Lymphocytes / Q000276:immunology / Q000648:ultrastructure
Izmeneniia khromosom u bol'nykh ostroĭ dizenterieĭ i ikh sviaz' s immunologicheskimi sdvigami.