Monosomy 21, partial duplication of chromosome 11, and structural abnormality of chromosome 1q21 in a case of lymphoma developing in a transplant recipient: characteristic abnormalities of secondary lymphoma?
Cytogenetic analysis by QFQ-banding of direct preparation of a testicular mass from a patient with secondary lymphoma revealed a modal chromosome number of 45,XY, including structural and numerical anomalies. The most consistent anomalies were the monosomy 21, duplication of the long arm of #11, and structural anomaly associated with chromosome #1 in band q21.
D000328:Adult; D016026:Bone Marrow Transplantation; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002880:Chromosomes, Human, Pair 11; D002891:Chromosomes, Human, Pair 21; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000473:pathology / Q000628:therapy*; D008223:Lymphoma / Q000235:genetics* / Q000473:pathology; D008297:Male; D009006:Monosomy; D005810:Multigene Family; D009378:Neoplasms, Multiple Primary / Q000235:genetics / Q000473:pathology