title: Corticosteroid therapy in adolescent patients.
abstract: Since their introduction in the 1950s, corticosteroids have become an important adjunct in the therapy for a wide variety of diseases. Improved guidelines for clinical applications and for reduction in undesirable effects have been achieved through a better understanding of corticosteroid mechanisms of action and pharmacokinetic properties. This discussion will review the indications and adverse effects associated with corticosteroid therapy. Emphasis will be placed on the important aspects of corticosteroid therapy in adolescent patients including recent advances essential to the development of guidelines for dosing and therapeutic monitoring.
mesh_terms: D000042:Absorption; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D011247:Pregnancy / Q000187:drug effects; D011485:Protein Binding; D013375:Substance Withdrawal Syndrome / Q000209:etiology
chemical_list: D000305:Adrenal Cortex Hormones