title: Drug reactions: allergy and near-allergy.
abstract: In this review, allergic drug reactions are discussed in terms of their immunologic mechanisms, with an emphasis given to new information that has appeared recently in the medical literature. Because of their recent emergence as important categories to recognize and manage appropriately, the pseudoallergic reactions next receive special attention. The last section on management covers diagnostic and preventive strategies, and concludes with a discussion of desensitization.
mesh_terms: D003888:Desensitization, Immunologic; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000145:classification / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D007158:Immunologic Techniques; D013601:T-Lymphocytes / Q000276:immunology