[Effect of autologous marrow transplantation on bone marrow recovery following large-field fractionated irradiation of dogs].
After large-field fractionated irradiation of dogs at a cumulative dose of 54 Gy, a stable bone marrow depletion occurs persisting for a year following irradiation. The automyelotransplantation after the end of the exposure elicits a transient recovery of the exposed bone marrow, 1.5-2 months after the beginning of irradiation, followed by a secondary depletion of the exposed haemopoietic sites. The control and the automyelotransplanted animals exhibited bone marrow recovery one year and six months after irradiation, respectively, the cellularity being maintained at a high level for 3 years of observation.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology / Q000528:radiation effects; D016026:Bone Marrow Transplantation; D002452:Cell Count / Q000528:radiation effects; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006410:Hematopoiesis / Q000528:radiation effects; D008297:Male; D013997:Time Factors; D014182:Transplantation, Autologous
Vliianie automielotransplantatsii na vostanovlenie kostnogo mozga posle krupnopol'nogo fraktsionirovannogo oblucheniia sobak.