Quantification of vaginal Candida albicans infections in rodents.
Estradiol-treated mice and estradiol-treated ovariectomized rats support vaginal infections with Candida albicans for several months; low-grade uterine infections occur in around half the animals. A comparison has been made and the relative advantages discussed of quantifying these infections by sampling with a wire loop and plating on BiGGY agar, sampling by vaginal washing, or removal and homogenization of the vagina followed by dilution and plate counting.
D000818:Animals; D002176:Candida albicans / Q000254:growth & development*; D002181:Candidiasis, Vulvovaginal / Q000382:microbiology*; D002584:Cervix Uteri / Q000382:microbiology; D005260:Female; D051379:Mice; D051381:Rats; D014599:Uterus / Q000382:microbiology; D014621:Vagina / Q000382:microbiology