A review of study findings of the risks and benefits of oestrogen therapy in the female climacteric.
A literature review was conducted to assess the evidence regarding the risks and benefits of oestrogen therapy in climacteric women. Consideration was given to the route of administration, effects on lipid levels, the skin and urinary symptoms, endometrial cancer, mortality and replacement therapy. It was concluded from the data examined that properly administered oestrogen treatment does not increase the risk of endometrial cancer and that the relative risk of death in oestrogen users aged over 40 is markedly lower than than in non-users.
D000328:Adult; D000368:Aged; D002979:Climacteric / Q000502:physiology*; D004967:Estrogens / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009026:Mortality; D012306:Risk; D012867:Skin / Q000033:anatomy & histology; D014570:Urologic Diseases / Q000188:drug therapy / Q000209:etiology; D014594:Uterine Neoplasms / Q000139:chemically induced
D004967:Estrogens