Successful pregnancy after pharmacologic suppression of a circulating anticoagulant in a woman with previous pregnancy losses and pulmonary emboli. A case report.
A woman had two second-trimester fetal deaths two weeks after genetic amniocenteses, and her puerperal courses were also complicated by pulmonary emboli. During her next pregnancy a circulating anticoagulant was demonstrated that had been absent between her pregnancies. It was suppressed with aspirin and prednisone. Amniocentesis was uneventful. Despite the development of steroid-induced diabetes, the pregnancy outcome was successful, with no postpartum complications.
D000328:Adult; D001241:Aspirin / Q000627:therapeutic use*; D001777:Blood Coagulation; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D007231:Infant, Newborn; D010314:Partial Thromboplastin Time; D011241:Prednisone / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000150:complications*
D007136:Immunoglobulins; C019158:circulating anticoagulants; D001241:Aspirin; D011241:Prednisone