[Treatment of mastopathies with cyclic mastodynia. Clinical results and hormonal profiles].
The therapeutic effect of a long-term Gestagen therapy (lynestrenol) and a phytotherapy (Mastodynon) in comparison to a placebo group is reported in 160 cases of severe mastopathy with cyclic mastalgia. In 82.1 percent of the patients in the gestagen-group and in 74.5 percent of the patients in the Mastodynon-group a good relief of the premenstrual symptoms was achieved. In the placebo group only 36.8 percent of the patients reported a relief of symptoms. The difference is significant. The evaluation and analysis of serum HPRL and serum-progesterone showed a significant rise of the HPRL-level and a significant decrease of the progesterone-level. Because of this severe influence on the endocrine balance the recommendation for an alternative phytotherapy prior to a long term gestagen therapy is justified.
D001941:Breast Diseases / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008234:Lynestrenol / Q000627:therapeutic use*; D010146:Pain / Q000503:physiopathology*; D010507:Periodicity; D010936:Plant Extracts / Q000627:therapeutic use*; D011374:Progesterone / Q000097:blood*; D011388:Prolactin / Q000097:blood*; D011897:Random Allocation
D010936:Plant Extracts; D011374:Progesterone; C012413:mastodynon; D011388:Prolactin; D008234:Lynestrenol
Traitement de la mastopathie avec mastodynie cyclique. Résultats cliniques et profils hormonaux.