Fatty acid pattern of red blood cell membranes and risk of ischemic brain infarction: a case-control study.
The fatty acid composition of red blood cell membranes (which reflects dietary fat intake) was studied in 28 male patients with recent (less than 3 days) ischemic stroke and 56 matched controls. Fifteen fatty acids were measured by means of chromatographic analysis. Percentages of linoleic, 22:5, and 22:6 acids were significantly lower in red blood cell membranes of stroke patients than in those of matched controls. The results suggest that a low unsaturated fatty acid diet could be an independent risk factor for ischemic brain infarction.
D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000097:blood*; D002544:Cerebral Infarction / Q000097:blood*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005227:Fatty Acids / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000097:blood; D012306:Risk
D005227:Fatty Acids; D008055:Lipids; D010713:Phosphatidylcholines