[Evaluation of the antimicrobial action of substances for the setting of hygienic standards].
The notion of antimicrobial effect threshold as an index of hygienic importance for toxicological estimation of chemotherapeutic agents is grounded by the generally accepted conception of thresholds of substances harmful effect. The methodical means used in determining the antimicrobial effect threshold including the recommended set of the measurable indices of intestinal microflora are discussed.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects*; D002432:Cecum / Q000382:microbiology; D004305:Dose-Response Relationship, Drug; D005243:Feces / Q000382:microbiology; D008452:Maximum Allowable Concentration; D008826:Microbial Sensitivity Tests; D051381:Rats; D013997:Time Factors
D000900:Anti-Bacterial Agents
Otsenka antimikrobnogo deĭstviia veshchestv s tsel'iu gigienicheskogo normirovaniia.