[Action of cytoplasmic factors from the regenerating liver on cholesterol esterification in the blood serum of rats with tetrachloromethane liver damage].
The effect of proliferation stimulating factors (PSF) obtained from regenerating liver on the cholesterol esterification in blood serum under deep tetrachloromethane intoxication has been studied in experiments with white rats. Three phases in dynamics of cholesterol content in blood serum have been picked out after a single tetrachloromethane injection. The content of total cholesterol and cholesterol esters reduces during the first phase (24 h), during the second phase (3-7th day) it increases and during the third phase (15th day) these values become normal. PSF injection does not produce any influence on the nature of blood cholesterol under deep tetrachloromethane intoxication, but stimulates the processes of cholesterol ester formation in blood serum.
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D002788:Cholesterol Esters / Q000097:blood*; D003593:Cytoplasm / Q000502:physiology*; D004951:Esterification; D006498:Hepatectomy; D008075:Lipoproteins, HDL / Q000097:blood; D008099:Liver / Q000187:drug effects*; D008115:Liver Regeneration; D008297:Male; D008970:Molecular Weight; D011506:Proteins; D051381:Rats; D013997:Time Factors
D002788:Cholesterol Esters; D008075:Lipoproteins, HDL; D011506:Proteins; D002784:Cholesterol
Deĭstvie tsitoplazmaticheskikh faktorov iz regeneriruiushcheĭ pecheni na éterifikatsiiu kholesterina v syvorotke krovi krys pri povrezhdenii pecheni tetrakhlormetanom.