title: [Whole blood viscosity in patients with acral arterial occlusive diseases and their modification by rheologically active drugs].
abstract: Measurements of the whole-blood viscosity in patients with organic and functional disturbances of the acral blood supply were performed. In comparison with the whole-blood viscosity in normal persons patients with acral occlusive diseases showed a significantly increased viscosity. On the other hand, in patients with functional disturbances of the acral blood supply no differences could be established. In a therapy study the good efficacy of rheologically effective medicaments could be demonstrated particularly as combination therapy of pentoxifylline, acetylsalicylic acid and tolazoline in patients with acral occlusive diseases. These medicaments should by all means be used together with the basic therapy. In functional disturbances of the blood supply should predominantly be maintained physiotherapeutic methods of treatment.
mesh_terms: D000328:Adult; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D001241:Aspirin / Q000627:therapeutic use*; D001809:Blood Viscosity / Q000187:drug effects*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010431:Pentoxifylline / Q000627:therapeutic use*; D011928:Raynaud Disease / Q000188:drug therapy*; D012212:Rheology; D013805:Theobromine / Q000031:analogs & derivatives*; D014043:Tolazoline / Q000627:therapeutic use*
chemical_list: D014043:Tolazoline; D013805:Theobromine; D001241:Aspirin; D010431:Pentoxifylline
vernacular_title: Die Vollblutviskosität bei Patienten mit akralen arteriellen Durchblutungsstörungen und ihre Beeinflussung durch rheologisch wirksame Medikamente.