[Carrier-bound measurement of serum theophylline levels in children].
Long time treatment of asthma in children with theophylline requires therapeutic drug monitoring by determination of serum concentrations. Beside established assays a carrier-bound reagent test has recently been developed, which has been demonstrated to be accurate, precise and cheaper than other assays. It has the advantage to give rapid results within minutes, which makes it suitable for intensive care units as well as for outpatient care.
D000293:Adolescent; D000911:Antibodies, Monoclonal; D001249:Asthma / Q000097:blood* / Q000188:drug therapy; D001666:Binding Sites, Antibody; D002648:Child; D002675:Child, Preschool; D005454:Fluorescence Polarization; D006801:Humans; D011934:Reagent Strips; D011983:Receptors, Purinergic / Q000378:metabolism*; D013806:Theophylline / Q000097:blood* / Q000627:therapeutic use
D000911:Antibodies, Monoclonal; D011934:Reagent Strips; D011983:Receptors, Purinergic; D013806:Theophylline
Untersuchungen zur Träger-gebundenen Messung von Serum-Theophyllin-Spiegeln bei Kindern.