title: Thermosensitivity of dorsal raphe neurons in vitro.
abstract: Thermosensitivity of raphe neurons was studied in tissue slices of rat brainstems (400-500 micron). Measurement of activity of single cells in the dorsal raphe region of the slices revealed that the majority of neurons (89%) were sensitive to changes in temperature. Over the range 34 to 42 degrees C, 3 classes of thermosensitive cells were found: warm (61%), cold (15%) and biphasic type cells (13%). Many dorsal raphe neurons may be intrinsically temperature sensitive and may serve as extrahypothalamic thermodetector components in the integrative process of central thermoregulation.
mesh_terms: D000818:Animals; D001833:Body Temperature Regulation; D001931:Brain Mapping; D003080:Cold Temperature; D005071:Evoked Potentials; D006358:Hot Temperature; D007031:Hypothalamus / Q000502:physiology; D011903:Raphe Nuclei / Q000502:physiology*; D051381:Rats; D013823:Thermoreceptors / Q000502:physiology*