[A study of Chlamydia trachomatis infection in gynecological outpatients--direct specimen test and chlamydial IgG antibodies].
Among 226 outpatients, 30(13.3%) harboured Chlamydia trachomatis in the cervix. C. trachomatis was found in 15.1% of the patients with lower genital tract infection, 8.0% of pregnant women, 0.0% of sterile women, 14.3% of patients with pelvic inflammation and 88.9% of sexual partners respectively. The frequency of C.trachomatis infection in those 50 years old or more was 0.0%. One hundred and sixty-six women were also found to have titers of serum antibody to C.trachomatis. Serum IgG antibodies were found in 64 of 166(38.6%). Serum IgG antibodies were positive in 66.7% of the Chlamydia-positive women (20/30 subjects), whereas the positive rate was 31.0% in the Chlamydia-negative women (39/126 cases). In 40.0% of chlamydia positive patients, there was seen a significant rise in the number of paired sera. For C. trachomatis infection treatment with minocycline 100mg p.o. twice a day was effective (100%).
D002690:Chlamydia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000276:immunology* / Q000302:isolation & purification; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D008911:Minocycline / Q000627:therapeutic use; D011247:Pregnancy
D007074:Immunoglobulin G; D008911:Minocycline