Serum and urinary uric acid in primary hyperparathyroidism.
Serum and 24-h urinary uric acid were measured in 29 patients with primary hyperparathyroidism pre- and post-operatively. No significant difference was observed. A positive correlation was found between the ratios of urinary calcium/creatinine and urinary uric acid/creatinine pre-operatively but not after surgery. The serum uric acid level showed an increase from the first to the third day post-operatively and returned to normal within a week, but in patients undergoing other urological operations there was no post-operative increase. On a low calcium diet the level of serum uric acid was found to be increased. These findings suggest that primary hyperparathyroidism has some influence on uric acid metabolism.
D000328:Adult; D002118:Calcium / Q000097:blood / Q000652:urine; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011300:Preoperative Care; D014527:Uric Acid / Q000097:blood / Q000378:metabolism* / Q000652:urine
D014527:Uric Acid; D002118:Calcium