[Effect of intracoronary thrombolytic therapy on the development of the complications of myocardial infarction].
The incidence of myocardial infarction complications, detectable clinically or echocardiographically, was evaluated in 2 groups of patients: 62 patients treated with selective intracoronary thrombolysis (SIT) and 40 conventionally treated controls (C). Local femoral arterial lesions or hemorrhages developed in 16% of SIT patients, while intracardiac thrombosis was more frequent in the controls (35% versus 6% in the former; p less than 0.001). Left ventricular dyskinesias and heart failure were apparently less common in the SIT patients, however the differences were not significant. The comparison between patients with successful and stable recanalization and the controls showed significant differences, however; the incidence of left ventricular dyskinesias was 9% and 38% (p less than 0.005), respectively, the incidence of heart failure was 0% and 30% (p less than 0.001), and the incidence of intracardiac thrombosis was 3% and 35% (p less than 0.001). Differences in mortality rates were not significant between the two groups (0% for SIT versus 10% for controls).
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000517:prevention & control; D003331:Coronary Vessels; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006333:Heart Failure / Q000517:prevention & control; D006341:Heart Rupture / Q000517:prevention & control; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D011379:Prognosis; D012770:Shock, Cardiogenic / Q000517:prevention & control; D013923:Thromboembolism / Q000517:prevention & control
D005343:Fibrinolytic Agents
Vliianie vnutrikoronarnogo tromboliticheskogo lecheniia na poiavlenie oslozhneniĭ infarkta miokarda.