title: Treatment of severe hypertension with peroral labetalol.
abstract: 22 patients with untreated, essential hypertension (diastolic blood-pressure greater than or equal to 140 mmHg) and in most cases also showing neurological symptoms were given a single oral dose of 400 mg labetalol. All patients displayed a gradual decrease of the blood-pressure down to a diastolic pressure about 110 mmHg with relief of the symptoms. There were no signs of neurological deficit due to the reduction of blood-pressure.
mesh_terms: D000284:Administration, Oral; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007741:Labetalol / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis
chemical_list: D007741:Labetalol