Cerebrospinal fluid findings in neurological manifestations of Lyme disease.
The cerebrospinal fluid (CSF) findings in 21 patients with different manifestations of Lyme disease are presented. 15 patients exhibited CSF changes including a lymphoplasmocytic pleocytosis and a CSF protein profile indicating a barrier leakage combined with an intrathecal immunoglobulin synthesis. Six patients-mainly suffering from cranial neuritis-had a normal CSF.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D002097:C-Reactive Protein / Q000032:analysis; D002555:Cerebrospinal Fluid / Q000166:cytology; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D002648:Child; D005260:Female; D005947:Glucose / Q000134:cerebrospinal fluid; D006801:Humans; D007136:Immunoglobulins / Q000134:cerebrospinal fluid; D008193:Lyme Disease / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid*
D001786:Blood Glucose; D002556:Cerebrospinal Fluid Proteins; D007136:Immunoglobulins; D002097:C-Reactive Protein; D005947:Glucose