title: Bile acids in serum, ultrafiltrate of serum and saliva from patients with cholestatic jaundice.
abstract: Individual bile acid conjugates in serum, the ultrafiltrate of serum and in saliva from patients with cholestatic jaundice were determined by gas-liquid chromatography. The bile acid concentration in the ultrafiltrate was 4-20% of that in serum and had also a different composition, with higher ratio of cholic to chenodeoxycholic acid. In saliva, the bile acid concentration was 1-8% of that in serum and the composition was different due to a higher proportion of unconjugated cholic acid. The results indicate that neither the bile acid concentration in the ultrafiltrate, nor that in saliva corresponds to the non-protein-bound bile acids in serum.
mesh_terms: D000328:Adult; D000368:Aged; D001647:Bile Acids and Salts / Q000032:analysis*; D001769:Blood; D002635:Chenodeoxycholic Acid / Q000032:analysis; D001651:Cholestasis, Extrahepatic / Q000378:metabolism*; D002780:Cholestasis, Intrahepatic / Q000378:metabolism*; D002793:Cholic Acids / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D012463:Saliva / Q000032:analysis*; D014462:Ultrafiltration
chemical_list: D001647:Bile Acids and Salts; D002793:Cholic Acids; D002635:Chenodeoxycholic Acid