title: Differences in the hydrophobic properties of discrete alpha-helical domains of rat and human apolipoprotein A-IV.
abstract: The primary structure of human apolipoprotein A-IV has been analyzed to identify amphipathic alpha-helical regions and compare their hydrophobic properties with analogous segments of rat apolipoprotein A-IV. Significant differences were found in the mean hydrophobicity and/or mean helical hydrophobic moment of several discrete alpha-helical domains of rat and human apolipoprotein A-IV, which may determine the differences in their biophysical and biological behavior.
mesh_terms: D000818:Animals; D001054:Apolipoproteins A; D001665:Binding Sites; D006801:Humans; D008055:Lipids; D011487:Protein Conformation; D051381:Rats; D013045:Species Specificity
chemical_list: D001054:Apolipoproteins A; D008055:Lipids; C022205:apolipoprotein A-IV