Long-term effect of repeated short oxygen exposition on blood pressure development and erythrocyte sodium content in SHR and WKY.
Repeated short oxygen exposition (60 min weekly, beginning at the 1st week of age up to the 18th week of age) induced in male spontaneously hypertensive rats (SHR) a diminished blood pressure rise. Oxygen exposed SHR had also lower heart rates than SHR without oxygen exposition. No significant differences were found in both these parameters in normotensive rats (WKY). Furthermore oxygen exposition decreased the erythrocyte sodium content of SHR.
D000375:Aging / Q000097:blood; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D004912:Erythrocytes / Q000032:analysis* / Q000187:drug effects; D006339:Heart Rate; D008297:Male; D010100:Oxygen / Q000494:pharmacology*; D011188:Potassium / Q000097:blood; D051381:Rats; D011918:Rats, Inbred SHR / Q000097:blood* / Q000145:classification; D011919:Rats, Inbred Strains / Q000097:blood*; D012964:Sodium / Q000097:blood*; D013045:Species Specificity
D012964:Sodium; D011188:Potassium; D010100:Oxygen