Suramin increases the nonspecific antibacterial resistance through macrophage activation.
D000818:Animals; D001424:Bacterial Infections / Q000188:drug therapy / Q000276:immunology / Q000401:mortality; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D007113:Immunity, Innate / Q000187:drug effects*; D008262:Macrophage Activation / Q000187:drug effects*; D051379:Mice; D008813:Mice, Inbred ICR; D010587:Phagocytosis / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013498:Suramin / Q000494:pharmacology* / Q000627:therapeutic use
D013498:Suramin