[Clinico-morphologic analysis of human amyotrophic leukospongiosis reproduced in guinea pigs].
Fourteen guinea pigs were infected with brain suspension obtained from a patient who died from amyotrophic leukospongiosis. Eight animals (57.7%) developed the disease in 2-4 months (2 of 4 with intracerebral and 6 of 10 with intramuscular infection). Morphological CNS changes in the patient and the guinea pigs were very similar.
D000328:Adult; D000818:Animals; D002490:Central Nervous System / Q000473:pathology; D002493:Central Nervous System Diseases / Q000209:etiology* / Q000473:pathology; D004195:Disease Models, Animal; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D009046:Motor Neurons; D009468:Neuromuscular Diseases / Q000209:etiology* / Q000473:pathology; D012897:Slow Virus Diseases / Q000473:pathology / Q000635:transmission*
Kliniko-morfologicheskiĭ analiz amiotroficheskogo leĭkospongioza cheloveka, vosproizvedennogo na morskikh svinkakh.