Inhibitory synaptic input to edge cells during fictive locomotion.
Edge cells are stretch receptors with receptive fields in the lateral margin of the lamprey spinal cord. Their activity may entrain the spinal central pattern generator (CPG). We have recorded intracellularly from edge cells during short episodes of fictive locomotion. Every cell tested exhibited numerous chloride-sensitive IPSPs. We have therefore provided evidence that edge cell sensitivity is modulated by the activity of the spinal CPG.
D000818:Animals; D005246:Feedback; D005399:Fishes / Q000502:physiology*; D007798:Lampreys / Q000502:physiology*; D008124:Locomotion; D008465:Mechanoreceptors / Q000502:physiology*; D009433:Neural Inhibition; D013116:Spinal Cord / Q000502:physiology*; D013569:Synapses / Q000502:physiology