title: [Correction of a glottis gap by injection of collagen. Apropos of 25 cases].
abstract: Results of treatment of patulous glottis by injection of collagen are discussed. The technique used differs little from that in which Teflon is employed, the difference being that the collagen paste is injected into Reinke's space. The quantity deposited varies between 1 and 1.5 cm3. Twenty-five patients had been treated in this way by April 1986, the longest follow up being for 19 months (mean: 9.5 months). The compound presents remarkable tolerance and no complication has been noted up to the present. Results were at least equal to those obtained using Teflon. Vocal quality was evaluated, apart from by vocal recordings, by analysis of vocal spectrum and objective measurements such as phonatory quotient and output. Results appear to be stable and although some reduction in quantity injected was noted most of the collagen becomes living tissue by colonization with host tissue. Availability of new generations of collagen such as that crosslinked at 35 mg/ml will probably resolve definitely the problem of persistence of results.
mesh_terms: D000328:Adult; D000368:Aged; D003094:Collagen / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D005931:Glottis / Q000473:pathology*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014826:Vocal Cord Paralysis / Q000628:therapy*
chemical_list: D003094:Collagen
vernacular_title: La correction de la béance glottique par injection de collagène. A propos de 25 cas.