A novel acyl-CoA-binding protein from bovine liver. Effect on fatty acid synthesis.
Bovine liver was shown to contain a hitherto undescribed medium-chain acyl-CoA-binding protein. The protein co-purifies with fatty-acid-binding proteins, but was, unlike these proteins, unable to bind fatty acids. The protein induced synthesis of medium-chain acyl-CoA esters on incubation with goat mammary-gland fatty acid synthetase. The possible function of the protein is discussed.
D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism* / Q000494:pharmacology; D002417:Cattle; D002850:Chromatography, Gel; D004591:Electrophoresis, Polyacrylamide Gel; D064429:Fatty Acid Synthases / Q000378:metabolism; D050556:Fatty Acid-Binding Proteins; D005227:Fatty Acids / Q000096:biosynthesis*; D005260:Female; D006041:Goats; D007525:Isoelectric Focusing; D007774:Lactation / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D008321:Mammary Glands, Animal / Q000187:drug effects / Q000201:enzymology; D009363:Neoplasm Proteins; D011247:Pregnancy
D002352:Carrier Proteins; D050556:Fatty Acid-Binding Proteins; D005227:Fatty Acids; D009363:Neoplasm Proteins; D064429:Fatty Acid Synthases