New 23-valent pneumococcal vaccine in relation to pneumococcal serotypes in systemic and non-systemic disease.
The serotype distribution of 3631 strains of Streptococcus pneumoniae, isolated from various specimens obtained from patients was determined by coagglutination and included serotyping within a total of 13 serogroups. The results of serotyping of isolates from Scotland demonstrated that the new 23-valent pneumococcal vaccine includes serotypes which accounted for 91% strains associated with systemic disease and 79% strains isolated from other anatomical sites. Altogether, 114 strains (3.1%) were not typable because they did not possess a type-specific capsule; these were commonly isolated from eyes (12%).
D001428:Bacterial Vaccines / Q000276:immunology*; D006801:Humans; D011008:Pneumococcal Infections / Q000382:microbiology*; D022242:Pneumococcal Vaccines; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D012606:Scotland; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000276:immunology* / Q000302:isolation & purification
D001428:Bacterial Vaccines; D022242:Pneumococcal Vaccines; D011135:Polysaccharides, Bacterial