[Relation between the dynamics of early ultrastructural changes in the cerebral cortex of the rat and radiation dose].
The electron microscopic investigation of the sensomotor zone in the cerebral cortex of mature male rats after total neutron and gamma radiation of high doses has demonstrated, that during first three hours after the influence the dynamics of ultrastructural changes in neurons, glial elements and microcirculatory bed depends on the radiation dose. After gamma radiation of 150 Gy, destructive changes in neurons, increased permiability of blood capillaries and development of perivascular edema are noted at earlier time than after radiation dose of 10 Gy. When the greater dose of radiation is used, also earlier reaction of the barrier structures in the brain is observed.
D000818:Animals; D002540:Cerebral Cortex / Q000528:radiation effects*; D002560:Cerebrovascular Circulation / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D008297:Male; D008833:Microcirculation / Q000528:radiation effects; D008854:Microscopy, Electron; D009457:Neuroglia / Q000528:radiation effects; D009474:Neurons / Q000528:radiation effects; D009940:Organoids / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
Zavisimost' dinamiki rannikh ul'trastrukturnykh izmeneniĭ kory bol'shogo mozga krysy ot dozy radiatsionnogo vozdeĭstviia.