title: [Lectin receptors in transitional cell tumors of the bladder].
abstract: Binding sites for lectins of peanuts, soya-beans and concanavalin A were identified in the tissues of normal human urinary bladder and its transitional cell tumors (31 patients) using the lectin-peroxidase technique. No binding sites for any of the lectins were found in normal urothelium. Receptors for peanut and soya-bean lectins were observed on the plasma membranes of 20% of tumor cells in transitional cell papillomas. A diffuse distribution of those lectins in tumor cell cytoplasm was interpreted as a tendency to malignant transformation of tumor. There were no concanavalin A receptors in tumor cells.
mesh_terms: D000116:Acetylgalactosamine / Q000032:analysis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000032:analysis* / Q000473:pathology; D003208:Concanavalin A / Q000032:analysis; D005690:Galactose / Q000032:analysis; D006651:Histocytochemistry; D006801:Humans; D037102:Lectins / Q000032:analysis; D008297:Male; D008358:Mannose / Q000032:analysis; D008875:Middle Aged; D010212:Papilloma / Q000032:analysis* / Q000473:pathology; D019887:Peanut Agglutinin; D037121:Plant Lectins; D011975:Receptors, Mitogen / Q000032:analysis*; D030262:Soybean Proteins; D001743:Urinary Bladder / Q000032:analysis / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000032:analysis* / Q000473:pathology; D010835:Phytohemagglutinins
chemical_list: D000116:Acetylgalactosamine; D003208:Concanavalin A; D005690:Galactose; D037102:Lectins; D008358:Mannose; D019887:Peanut Agglutinin; D037121:Plant Lectins; D011975:Receptors, Mitogen; D030262:Soybean Proteins; C028824:soybean lectin; D010835:Phytohemagglutinins
vernacular_title: Retseptory nekotorykh lektinov v perekhodno-kletochnykh opukholiakh mochevogo puzyria.