title: Molecular genetics of Red biosynthesis in Streptomyces.
abstract: We have studied the molecular biology of undecylprodigiosin (Red) biosynthesis by Streptomyces coelicolor as a model system for understanding the genetic regulation of antibiotic biosynthesis. A collection of new red mutants was obtained using a directed screen. Regions of DNA involved in the transcriptional regulation of red gene expression were also isolated.
mesh_terms: D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics*; D009154:Mutation; D010957:Plasmids; D011353:Prodigiosin / Q000031:analogs & derivatives* / Q000096:biosynthesis; D013302:Streptomyces / Q000235:genetics / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; C047347:undecylprodigiosin; D011353:Prodigiosin