Aromatization of 19-norandrogens by equine testicular microsomes.
In the stallion testis, aromatase activity was localized in the microsomal fraction. Androgen aromatization occurred through the loss of 1 beta,2 beta hydrogen atoms and appeared to involve free sulfhydryl groups. A single enzyme system seemed to aromatize androgen and norandrogen at the same rate while having a much lower affinity for norandrogens.
D000375:Aging; D000728:Androgens; D000818:Animals; D001141:Aromatase / Q000302:isolation & purification / Q000378:metabolism*; D006736:Horses; D008297:Male; D008861:Microsomes / Q000201:enzymology*; D008928:Mitochondria / Q000201:enzymology; D013347:Subcellular Fractions / Q000201:enzymology; D013379:Substrate Specificity; D013737:Testis / Q000201:enzymology* / Q000254:growth & development; D014316:Tritium
D000728:Androgens; D014316:Tritium; D001141:Aromatase