[The function of enzymes for the antioxidative protection of the bone marrow cells in rats during irradiation, bone fracture and combined radiation injury].
The activity of superoxide dismutase, glutathione peroxidase, glutathione reductase and glutathione: dehydroascorbate oxidoreductase is lower in the bone marrow than in the liver. The changes in the cellular antioxidative enzymatic system during leg bones fracture and X-ray irradiation are more pronounced in the rat bone marrow, as compared to the liver. The data obtained are in keeping with selective bone-marrow radiosensitivity and with the effect of exogenous superoxide dismutase and glutathione as radioprotectors.
D000208:Acute Disease; D000818:Animals; D001853:Bone Marrow / Q000201:enzymology* / Q000528:radiation effects; D004798:Enzymes / Q000528:radiation effects*; D050723:Fractures, Bone / Q000201:enzymology*; D005979:Glutathione Peroxidase / Q000528:radiation effects; D005980:Glutathione Reductase / Q000528:radiation effects; D008099:Liver / Q000201:enzymology / Q000528:radiation effects; D008297:Male; D010084:Oxidation-Reduction / Q000528:radiation effects; D010088:Oxidoreductases / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D013482:Superoxide Dismutase / Q000528:radiation effects; D013997:Time Factors
D004798:Enzymes; D010088:Oxidoreductases; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase; C020666:glutathione dehydrogenase (ascorbate)
Sostoianie fermentov antiokislitel'noĭ zashchity kletok kostnogo mozga krys pri obluchenii, perelome kosti i kombinirovannoĭ radiatsionnoĭ travme.