[Circadian rhythm of uric acid levels of the serum in gout].
Uric acid concentration in the serum was investigated 3 times a day using the uricase method in 15 gout inpatients on a hypopurine diet with age- and sex-adjusted caloric content. The highest uric acid concentration was noted at 7 a. m., the lowest concentration value at 11 p. m. The highest renal clearance values were noted from 7 a. m. till 3 p. m., the lowest ones from 11 p. m. till 7 a. m. Similar regularities were noted in 15 rheumatoid arthritic patients, however uric acid concentration in the serum was lower and its renal excretion was 1.7 times more effective.
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000097:blood; D002940:Circadian Rhythm; D006073:Gout / Q000097:blood*; D006801:Humans; D007668:Kidney / Q000378:metabolism; D008657:Metabolic Clearance Rate; D014527:Uric Acid / Q000097:blood* / Q000378:metabolism
D014527:Uric Acid
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