title: [Effect of unithiol and acetylcysteine on lipid peroxidation and the erythrocyte antioxidant system in sensitized guinea pigs].
abstract: The effect of unithiol and acetylcysteine on lipid peroxidation, thioldisulfide equilibrium, glucose-6-phosphate dehydrogenase, glutathione reductase and lactate dehydrogenase activity and on erythrocyte resistance was studied in guinea-pigs during sensitization with C. maltosa. Sensibilized animals receiving thiol antioxidants showed partial restoration of normal biochemical levels.
mesh_terms: D000111:Acetylcysteine / Q000494:pharmacology*; D000818:Animals; D002175:Candida / Q000276:immunology; D004112:Dimercaprol / Q000031:analogs & derivatives*; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D005260:Female; D006168:Guinea Pigs; D007114:Immunization; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D010084:Oxidation-Reduction / Q000187:drug effects; D013997:Time Factors; D014494:Unithiol / Q000494:pharmacology*
chemical_list: D008054:Lipid Peroxides; D004112:Dimercaprol; D014494:Unithiol; D000111:Acetylcysteine
vernacular_title: Izuchenie vliianiia unithiola i atsetiltsisteina na perekisnoe okislenie lipidov i antioksidantnuiu sistemu éritrotsitov morskikh svinok pri sensibilizatsii.