Cell-cycle-regulated translation of histone mRNA in Physarum plasmodia.
In Physarum polycephalum, histone mRNA begins to accumulate 3 h before the S phase. We show that histone synthesis was limited to the S phase and that the mRNA that accumulated in the G2-phase cytoplasm could be translated in vitro. Thus, recruitment of stored mature histone mRNA did not occur until the S phase began.
D002453:Cell Cycle; D003593:Cytoplasm / Q000502:physiology; D005786:Gene Expression Regulation; D006657:Histones / Q000235:genetics*; D010804:Physarum / Q000166:cytology / Q000235:genetics*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics
D006657:Histones; D012333:RNA, Messenger