title: Plasma sex steroid binding in Chiroptera.
abstract: Plasma steroid binding was examined in samples obtained from seven species of bats representing four different families. A specific sex steroid-binding protein (SBP) was identified by steady-state polyacrylamide gel electrophoresis in representatives of two families, the phyllostomids and the vespertilionids. In these species, as in primates, SBP not only exhibited high affinity for the androgens testosterone and dihydrotestosterone (DHT), but also for estradiol. A specific SBP was not identified in the tropical American vampire bat or in the two species of pteropodids examined. In all species examined, except for the vampire bat, a specific corticosteroid-binding globulin (CBG) was also identified. In addition to binding glucocorticoids, CBG in these species appeared to bind androgens as well.
mesh_terms: D000818:Animals; D002685:Chiroptera / Q000097:blood*; D013196:Dihydrotestosterone / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D008297:Male; D011247:Pregnancy; D011485:Protein Binding; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism*; D013045:Species Specificity; D014156:Transcortin / Q000378:metabolism
chemical_list: D012738:Sex Hormone-Binding Globulin; D013196:Dihydrotestosterone; D004958:Estradiol; D014156:Transcortin