[Possible correlations between the level of alcoholic motivation and the electrophysiological structure of sleep in the rat].
Using modified Porsolt's method, the electrophysiological sleep pattern was studied in normal conditions and after a single intraperitoneal ethanol injection to noninbred male albino rats divided into 2 groups ("high activity" and "low activity" rats). Voluntary alcohol intake in these rats was measured during free choice between 10% ethanol and water for 20 days. "Low activity" rats were characterized by a statistically significant 3.4-fold higher level of ethanol consumption and 2.7-fold longer REM-sleep stage, as compared to "high activity" animals. In "low activity" animals ethanol (1 g/k, 10% solution, i. p.) inhibits and in "high activity" rats it increases REM-sleep stage, thus removing differences in the sleep pattern in the two groups of rats. The data obtained suggest a possible role of REM-sleep in the development of alcohol motivation.
D000428:Alcohol Drinking / Q000502:physiology*; D000818:Animals; D004569:Electroencephalography; D008297:Male; D009042:Motivation / Q000502:physiology*; D051381:Rats; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology
Vozmozhnye korreliatsii mezhdu urovnem alkogol'noĭ motivatsii i élektrofiziologicheskoĭ strukturoĭ sna u krys.