Use of an ellipsoid artificial heart.
Experiments with the Poisk model of an ellipsoid artificial heart are reported. With a modified model of the diaphragm type made from polyurethane, calves survived for a mean of 55 days, with a maximum survival of 3 months. With adequate anticoagulation therapy, no thrombogenesis was observed in the blood chamber (except for the inlet valves); a low level of plasma hemolysis was observed postoperatively. Good correlation was demonstrated between the stroke volume and left and right atrial pressures. Changes in the blood coagulation indices are reported. Implantation of a clinical variant of this prosthesis into human cadavers demonstrated no difficulties in placing the heart in the pericardial cavity. Developmental efforts are continuing.
D000818:Animals; D001777:Blood Coagulation; D002417:Cattle; D005069:Evaluation Studies as Topic; D006354:Heart, Artificial; D006439:Hemodynamics; D011474:Prosthesis Design