[Effect of ephedrine on the blood supply and oxygen regimen of the brain during motion sickness].
In chronic experiments on conscious rabbits it was found by the method of hydrogen clearance and polarography that intravenous injections of ephedrine hydrochloride (1 and 5 mg/kg) attenuate cerebral vessels reactions in vestibular disorders caused by sickness, reduce or prevent an increase of the blood flow in the brain as a whole or in individual cortical structures, exert no significant effect on oxygen tension in the brain.
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004809:Ephedrine / Q000627:therapeutic use*; D009041:Motion Sickness / Q000188:drug therapy* / Q000503:physiopathology; D010101:Oxygen Consumption / Q000187:drug effects*; D010313:Partial Pressure; D011817:Rabbits; D013997:Time Factors
D004809:Ephedrine
Vliianie éfedrina na krovosnabzhenie i kislorodnyĭ rezhim golovnogo mozga pri ukachivanii.