title: Experimental popliteal vein thrombosis.
abstract: A device for experimental popliteal vein 'thrombosis' was developed and tested on a group of eight normal volunteers. Scintigraphy of the vessels and plethysmographic venous emptying recordings were performed as test procedures. The experimental set-up consisted of a syringe piston connected to a manometer and pump. A graded pressure was exerted on the dorsal aspect of the vein visualized with gamma-camera after in vitro labelling of the autologous red blood cells with 99Tcm. The position of the piston was controlled with a cobalt marker. The device proved successful and may be used when evaluating noninvasive diagnostic methods for detecting deep vein thrombosis and studying the haemodynamic consequences of acute venous thrombosis.
mesh_terms: D000328:Adult; D004912:Erythrocytes; D006801:Humans; D008875:Middle Aged; D011152:Popliteal Vein; D011312:Pressure; D011877:Radionuclide Imaging; D013667:Technetium; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D013667:Technetium