A profile of plasma branched chain amino acids in a totally pancreatectomized patient: effects of glucagon replacement under a steady feeding state.
Physiological amounts of glucagon replacement brought about the reduction of plasma branched chain amino acid levels as well as glucogenic amino acid levels in a totally pancreatectomized patient who was under a steady feeding state, i.e., constant administration of an elemental diet combined with continuous subcutaneous insulin infusion. This finding suggests that glucagon may play a physiological role not only on glucogenic amino acids but also branched chain amino acids in plasma in feeding state.
D000597:Amino Acids, Branched-Chain / Q000097:blood*; D001786:Blood Glucose / Q000378:metabolism; D005934:Glucagon / Q000097:blood / Q000627:therapeutic use*; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy / Q000009:adverse effects*
D000597:Amino Acids, Branched-Chain; D001786:Blood Glucose; D005934:Glucagon