Synthesis and chromatographic properties of S-(1-carboxyethyl)-L-cysteine and S-(1-carboxypropyl)-L-cysteine.
Details are reported for the synthesis of S-(1-carboxyethyl)-L-cysteine (1-CEC) and S-(1-carboxypropyl)-L-cysteine (1-CPC) from cysteine and 2-bromopropionic acid or 2-bromobutyric acid, respectively. Some analytical data and the behaviour of these two compounds on paper and ion-exchange chromatography are also reported, which allow their identification.
D000594:Amino Acid Oxidoreductases / Q000378:metabolism; D002233:Carbocysteine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D003545:Cysteine / Q000031:analogs & derivatives*; D050830:L-Amino Acid Oxidase; D009682:Magnetic Resonance Spectroscopy; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
C052226:S-(1-carboxyethyl)cysteine; C052225:S-(1-carboxypropyl)cysteine; D002233:Carbocysteine; D000594:Amino Acid Oxidoreductases; D050830:L-Amino Acid Oxidase; D003545:Cysteine