title: Carcinoma of the nasal vestibule treated with radiation therapy.
abstract: Twenty-two patients with squamous carcinoma of the nasal vestibule were treated at the University of Florida Division of Radiation Therapy with curative intent. Fifteen lesions were de novo and seven recurrent after surgery. By AJCC classification, 7 lesions were Tx or T1, 2 were T2, 2 were T3, and 11 were T4. Management of the primary tumor and regional lymphatic drainage was highly individualized. Local control was achieved in 19 out of 22 lesions. The ultimate regional lymph node control rate was 22 out of 22, although two patients required radical neck dissection after development of lymph node disease in untreated regional lymphatics. Two patients have died of cancer and three of intercurrent disease. Cosmetic results are generally excellent but may be compromised by previous surgery in recurrent lesions or tumor destruction of normal tissues in advanced lesions. Complications of treatment are minimal.
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D006801:Humans; D037981:Neck Dissection; D009364:Neoplasm Recurrence, Local; D009669:Nose Neoplasms / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology; D012878:Skin Neoplasms / Q000532:radiotherapy*