Paracetamol analysis: evaluation of a new kit for enzymatic assay.
Paracetamol in serum was assayed by a new enzymatic method, and the results compared with a high performance liquid chromatographic method. Results by the two procedures agreed well (t = 0.05). The correlation coefficient was 0.999, and the slope and intercept by Deming analysis were 0.975 and 0.003 mmol/l respectively. The enzymatic method represents a simple, accurate, precise and not too costly method with several advantages over many currently used techniques. It is eminently suitable for the smaller laboratory, and for use out of normal hours.
D000082:Acetaminophen / Q000097:blood* / Q000506:poisoning; D001774:Blood Chemical Analysis / Q000295:instrumentation / Q000379:methods*; D005069:Evaluation Studies as Topic; D006801:Humans; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D012459:Salicylates / Q000494:pharmacology; D020156:Salicylic Acid
D011933:Reagent Kits, Diagnostic; D012459:Salicylates; D000082:Acetaminophen; D020156:Salicylic Acid