[Effect of chronic stimulation of the emotionogenic zones of the hypothalamus on the status of carbohydrate metabolism in the rabbit].
In chronic experiments on rabbits receiving for 3 months low doses of cholesterol (60 mg per 1 kg of body weight daily), a repeated prolonged (2 h daily) intermittent stimulation of negative and positive emotive zones of the hypothalamus through implanted electrodes (eliciting avoidance and self-stimulation reactions correspondingly),--resulted in uniform disturbances of carbohydrate metabolism. There was a significant reduction of glucose tolerance in comparison with the control group of rabbits with implanted electrodes, as well as a gradual development of a slight, but stable neurogenic hyperglycemia. Simultaneously, in both experimental rabbits groups there were an equal increase of alimentary hypercholesterolemia and a development of persistent neurogenic arterial hypertension.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis*; D001794:Blood Pressure; D001931:Brain Mapping; D002682:Chinchilla; D002784:Cholesterol / Q000097:blood; D004036:Diet, Atherogenic; D004644:Emotions / Q000502:physiology*; D004924:Escape Reaction / Q000502:physiology; D007031:Hypothalamus / Q000502:physiology*; D012653:Self Stimulation / Q000502:physiology
D001786:Blood Glucose; D002784:Cholesterol
Vliianie khronicheskogo razdrazheniia émotsiogennykh zon gipotalamusa na sostoianie uglevodnogo obmena u krolikov.