Cardiac lipase: effect of ethanol and stress.
The effect of ethanol (0, 0.5, 3.0 g/kg) and restraint stress on cardiac neutral (NL) and lipoprotein (LPL) lipase was studied. Although ethanol (3.0 g/kg) or stress decreased NL and increased LPL, ethanol pretreatment significantly attenuated stress induced changes in both enzymes. These results support previous research on the protective effects of ethanol and may be one mechanism through which ethanol may alter susceptibility to certain forms of heart disease.
D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D006331:Heart Diseases / Q000209:etiology; D008049:Lipase / Q000378:metabolism*; D008071:Lipoprotein Lipase / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000201:enzymology
D000431:Ethanol; D008049:Lipase; D008071:Lipoprotein Lipase