title: A field evaluation of Nobi-Vac atrophic rhinitis vaccine.
abstract: A field trial was carried out with Nobi-Vac AR vaccine in 11 swine breeding herds. One herd suffered from severe B. bronchiseptica (BB+) rhinitis in piglets, while no clinical Atrophic Rhinitis (AR) was observed. Ten herds were described as AR problem herds, because clinical AR was observed for at least 1 year in spite of the fact that medication of sows and piglets was carried out and adequate housing and management systems were available in most herds. BB+ was isolated in 9 of these 10 farms and the AR pathogenic P. multocida (PM+) in all these farms. The trial started when piglets were born of sows which had been vaccinated 3 times. All piglets between 7 and 10 weeks old were examined clinically for AR. Nasal swabs from 20 pigs on each farm were screened bacteriologically for BB+ and PM+ every other month. A severe reoccurrence of AR was found in 2 of the 10 AR problem farms. In these 2 herds the 'all in-all out' system was not applied in farrowing and weaning houses. In the 8 other AR problem herds the percentage of pigs with AR decreased significantly below the average level of 1% per year. The percentage of pigs infected with BB+ and PM+ also decreased significantly. PM+ was significantly related to the percentage of clinical AR piglets. Seasonal effects contributed to a minor extent to the percentage of AR piglets. After 2.5 years of this trial PM+ could not be isolated during the last 12 months in six of the remaining AR problems herds. The conclusion is that Nobi-Vac AR vaccination of the sow gave protection against clinical AR in piglets on those farms (80%) which provided adequate housing and management systems.
mesh_terms: D000818:Animals; D001428:Bacterial Vaccines; D001884:Bordetella / Q000276:immunology*; D001885:Bordetella Infections / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary; D010325:Pasteurella / Q000276:immunology*; D010326:Pasteurella Infections / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary; D012008:Recurrence; D012222:Rhinitis, Atrophic / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D012621:Seasons; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary
chemical_list: D001428:Bacterial Vaccines