[Multifactorial method for assessing the physical work capacity of mice].
Based on the swimming test according to Kiplinger, in experiments on (CBA X C57BL)F1 mice there were elaborated criteria for animal performance evaluation in the process of repeated swimming of a standard distance thus measuring power, volume of work and rate of the fatigue development in relative units. From the study of effects of sydnocarb, bemethyl and phenazepam on various parameters of physical performance of mice a conclusion was made that the proposed method provides a more informative evaluation of the pharmacological effect on physical performance of animals as compared to the methods based on the record of time of performing the load.
D000818:Animals; D014151:Anti-Anxiety Agents; D001562:Benzimidazoles / Q000494:pharmacology; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000494:pharmacology; D055592:Biophysical Phenomena; D001703:Biophysics; D008297:Male; D051379:Mice / Q000502:physiology*; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010807:Physical Endurance / Q000187:drug effects; D012107:Research Design; D013550:Swimming; D013558:Sydnones / Q000494:pharmacology
D014151:Anti-Anxiety Agents; D001562:Benzimidazoles; D001570:Benzodiazepinones; D013558:Sydnones; D001569:Benzodiazepines; C017928:phenazepam; C049825:bemethyl; C009257:sidnocarb
Mnogofaktornyĭ metod otsenki fizicheskoĭ rabotosposobnosti mysheĭ.