[Evaluation of the status of peripheral nerves in patients on long-term treatment with anticonvulsants based on a study of H-reflex and F wave].
In 30 patients with chronic epilepsy treated mainly with diphenyl hydantoin the routine examination of motor conduction velocity and the H reflex and F wave were used for assessment of the state of the ulnar-median peroneal and tibial nerves. Slight abnormalities were found in the orthodromic motor impulse conduction and much greater and more frequent abnormalities in the conduction of late responses. These results confirm the opinions of a part of the authors on a neurotoxic effect on the peripheral nerves of long-term treatment with anticonvulsants.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use*; D001917:Brachial Plexus / Q000187:drug effects / Q000503:physiopathology; D002648:Child; D002908:Chronic Disease; D004827:Epilepsy / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction / Q000187:drug effects*; D010525:Peripheral Nerves / Q000187:drug effects / Q000503:physiopathology*; D010543:Peroneal Nerve / Q000187:drug effects / Q000503:physiopathology; D012023:Reflex, Monosynaptic / Q000187:drug effects*
D000927:Anticonvulsants
Ocena nerwów obwodowych u pacjentów przewlekle leczonych środkami przeciwpadaczkowymi przy pomocy odruchu H i fali F.