[Improvement of the solubility behavior of problem drugs. 9. In vitro absorption studies using melting solidification products of iomeglamic acid].
By means of the absorption apparatus according to Fürst and Neubert the solid dispersions of the iomeglamic acid were studied with regard to their in vitro absorption properties. All products showed better half lives of transport in relation to the pure compound. This was in correlation to the solubility parameters.
D000042:Absorption; D002626:Chemistry, Pharmaceutical; D005079:Excipients; D007462:Iodobenzenes / Q000032:analysis*; D010539:Permeability; D012995:Solubility
D005079:Excipients; D007462:Iodobenzenes; C002060:iomeglamic acid
Beiträge zur Verbesserung des Auflösungsverhaltens von Problemarzneistoffen. 9. Mitteilung: In-vitro-Resorptionsuntersuchungen mit lomeglamsäure-Schmelzerstarrungsprodukten.