Cap Z(36/32) is a contaminant and the major inhibitor of actin network formation in conventional actin preparations.
Previous studies have demonstrated that conventional actin preparations contain a potent factor which reduces the low shear viscosity of actin filaments. In this paper we demonstrate that Cap Z(36/32), a recently described protein from skeletal muscle that caps the barbed end of actin filaments and localizes to the Z-line of skeletal muscle, is the major factor affecting the low shear viscosity of actin prepared from muscle as described by Spudich and Watt.
D000199:Actins / Q000037:antagonists & inhibitors* / Q000302:isolation & purification; D000818:Animals; D002645:Chickens; D046911:Macromolecular Substances; D009124:Muscle Proteins / Q000302:isolation & purification* / Q000502:physiology; D009132:Muscles / Q000378:metabolism; D014783:Viscosity
D000199:Actins; C052696:Cap Z(36-32) muscle protein; D046911:Macromolecular Substances; D009124:Muscle Proteins