Onc genes and signals of cell growth.
Proto-onc genes are cellular genes controlling growth and differentiation. Their products form regulatory networks and include growth factors, receptors, signal transducers, amplifiers and nuclear proteins. Proto-onc genes have the potential to induce and maintain the cancerous phenotype of the cell if they are altered in structure or expression through transduction by a retrovirus or through in situ mutations.
D000818:Animals; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D009374:Neoplasms, Experimental / Q000235:genetics; D009857:Oncogenes; D011519:Proto-Oncogenes; D012190:Retroviridae / Q000235:genetics