title: [Biochemical complications of experimental vesico-sigmoidostomy].
abstract: Three experimental models of vesico-sigmoidostomy are studied (model-1, end to side V-S plus urethral ligation, model-2, end to end V-S, in "Y of Rous" plus urethral ligation and model-3, vesico-sigmoidoplasty), with aim of reproducing chemical imbalance observed in human subjects with ureterosigmoidostomy. Authors have evaluated clinical biochemical (serum acido-base balance, Cl, Na+, K+, BUN, creatinine, ammonia and albumin), and histologic variables in the first, third and fifth month after operation in 225 rats. Animal of model-1 presented more frequently than model-2 and model-3, alterations (hyperchloraemic acidosis, uraemia, hyperammonemia and hypoalbumin) as well as affectation of upper urinary system for acute or chronic pyelonephritis.
mesh_terms: D000818:Animals; D001835:Body Weight; D012809:Colon, Sigmoid / Q000601:surgery; D005260:Female; D007674:Kidney Diseases / Q000378:metabolism; D008660:Metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014547:Urinary Diversion / Q000009:adverse effects*
vernacular_title: Complicaciones bioquímicas de la vesicosigmoidostomía experimental.