title: Estimation of genetical parameters for a quantitative trait subject to major gene influences.
abstract: Both regression and correlation estimates of genetical variance and heritability for a quantitative trait influenced by a major gene can be obtained from the error variance-covariance matrix of MANOVA using relative-relative phenotype pairs as factors. The method is illustrated with parent-offspring data on red cell acid phosphatase phenotypes and serum acid phosphatase activity.
mesh_terms: D000135:Acid Phosphatase / Q000097:blood / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005786:Gene Expression Regulation; D006801:Humans; D010641:Phenotype; D013223:Statistics as Topic / Q000379:methods
chemical_list: D000135:Acid Phosphatase