Optimization of a membrane oxygenation system for cell culture in stirred tank reactors.
Bubble free aeration of animal cell cultures in conventional stirred tank reactors is performed with a silicone tubing oxygenation system. This system is characterized for the laboratory fermenter BIOSTAT M with 1.5 l working volume in respect to oxygen transfer and mixing performance.
D000818:Animals; D001709:Biotechnology / Q000295:instrumentation*; D002478:Cells, Cultured / Q000502:physiology*; D005285:Fermentation; D006825:Hybridomas / Q000502:physiology; D008567:Membranes, Artificial; D051379:Mice; D010100:Oxygen
D008567:Membranes, Artificial; D010100:Oxygen