title: Personality traits and platelet MAO activity in alcohol and drug abusing teenage boys.
abstract: The aim of this study has been to investigate whether teenage boys with mixed drug abuse differ from those with pure alcohol abuse as concerns personality traits and platelet monoamine oxidase activity. The series included 1129 consecutive 18-year-old males called to the Enlistment Center in the northern part of Sweden. A special inventory was constructed based on Zuckerman Sensation Seeking Scale (SSS), Eysenck's Personality Inventory (EPI), the Karolinska Scales of Personality (KSP) and questions about alcohol and drug consumption. The subjects with mixed drug abuse (n = 96) had high scores in the two subscales of SSS and KSP related to ability to stand boredom, high scores in both subscales of EPI and KSP related to impulsivity, high scores in Thrill and Adventure Seeking (TAS) and Experience Seeking (ES) of SSS as well as low platelet monoamine oxidase activity. The males with pure alcohol abuse (n = 33) also showed signs of monotony avoidance and impulsivity, but this type of abuse was not clearly related to low platelet monoamine oxidase activity and not to the aspects of curiosity included in the SSS such as TAS and ES. These findings are consistent with the picture earlier found as concerns "Type II" alcoholism which has an early onset, is genetically transmitted, is associated with mixed drug abuse and social complications.
mesh_terms: D000293:Adolescent; D000437:Alcoholism / Q000201:enzymology / Q000523:psychology*; D005106:Exploratory Behavior; D005120:Extraversion, Psychological; D006801:Humans; D007175:Impulsive Behavior / Q000523:psychology; D008297:Male; D008995:Monoamine Oxidase / Q000097:blood*; D010551:Personality; D010555:Personality Inventory; D019966:Substance-Related Disorders / Q000201:enzymology / Q000523:psychology*
chemical_list: D008995:Monoamine Oxidase