title: Parity as a factor in incontinence in multiple sclerosis.
abstract: Twelve consecutively selected patients with multiple sclerosis and incontinence had electrophysiologic studies performed of the pudendal and perineal innervations of the anal and urinary sphincter. Single-fiber electromyogram density measurements were obtained in the external anal sphincter. Fecal incontinence was found to be unexpectedly frequent. The results suggest that incontinence in patients with multiple sclerosis is often due to the interaction of several factors, including central lesions, lesions of the conus medullaris and, also, coincidental pelvic nerve lesions associated with childbirth. Thus, incontinence is especially a problem in women with this disease.
mesh_terms: D000200:Action Potentials; D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000503:physiopathology; D004576:Electromyography; D005242:Fecal Incontinence / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009103:Multiple Sclerosis / Q000150:complications / Q000503:physiopathology*; D009132:Muscles / Q000503:physiopathology; D010298:Parity; D010388:Pelvis / Q000294:innervation; D010525:Peripheral Nerves / Q000503:physiopathology; D011930:Reaction Time; D014549:Urinary Incontinence / Q000209:etiology / Q000503:physiopathology*