Relationship between chamber mechanical properties and mean pressure-mean flow diagram of the left ventricle.
We undertook a theoretical analysis of the source resistance of the left ventricle represented in a mean pressure-mean flow (P-Q) diagram, using the chamber properties established in terms of the pressure-volume relationship. This analysis showed that P-Q pairs of points should lie above the linear function proposed by Elzinga and Westerhof. A third-order polynomial function would theoretically explain better than a linear relation or a parabolic fit the curved shape of experimentally obtained P-Q relationships. The analysis resolves the discrepancy between Elzinga and Westerhof's theoretical concept of linear source resistance and the actual nonlinear P-Q relationship.
D000818:Animals; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D001794:Blood Pressure; D003326:Coronary Circulation; D006321:Heart / Q000502:physiology*; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D009200:Myocardial Contraction; D016276:Ventricular Function