title: Autoradiographic demonstration of the distribution of vagal afferent nerve fibers in the epiglottis of the rabbit.
abstract: After injection of [3H]leucine into the nodose ganglion of a rabbit autoradiographic examination of the distribution of vagal afferent fibers in the epiglottal wall revealed many nerve bundles of labeled afferent fibers present in the submucosal plexus between the cartilage tissue and the mucosa. The labeled afferent fibers, most of which were myelinated (while a few were unmyelinated), descended towards the mucosa, and then appeared to demyelinate at the subepithelial layer of the mucosa. The labeled afferent fibers entered the mucosal epithelium, terminated as free endings in the intercellular space among the epithelial cells, and extended near the mucosal surface. Grains were also observed near the taste buds in the epithelium, which suggests that some vagal afferent fibers innervated the epiglottal taste buds.
mesh_terms: D000818:Animals; D001345:Autoradiography; D004825:Epiglottis / Q000294:innervation*; D007930:Leucine / Q000378:metabolism; D008854:Microscopy, Electron; D009475:Neurons, Afferent / Q000378:metabolism; D011817:Rabbits; D013650:Taste Buds; D014630:Vagus Nerve / Q000033:anatomy & histology* / Q000378:metabolism
chemical_list: D007930:Leucine