Synthesis of the trypsin fragment 10-25/75-88 of mouse nerve growth factor. II. The unsymmetrical double chain cystine peptide.
The synthesis of the unsymmetrical double chain cystine peptide corresponding to sequence 10-25/75-88 of mouse nerve growth factor is described. The synthetic product was inactive in all bioassays examined; consequently, this portion of the NGF molecule did not represent or contain a lower molecular weight form of the neurotrophic factor.
D000595:Amino Acid Sequence; D000818:Animals; D003553:Cystine; D007202:Indicators and Reagents; D051379:Mice; D020932:Nerve Growth Factor; D009414:Nerve Growth Factors / Q000138:chemical synthesis*; D009904:Optical Rotation; D010446:Peptide Fragments / Q000138:chemical synthesis*; D014357:Trypsin
D007202:Indicators and Reagents; D009414:Nerve Growth Factors; D010446:Peptide Fragments; D003553:Cystine; D020932:Nerve Growth Factor; C051998:nerve growth factor (10-25,75-88); D014357:Trypsin