title: Prediction of fracture healing in the tibia by quantitative radionuclide imaging.
abstract: The uptake of 99mTc-MDP was studied in 73 patients after a tibial fracture. The image obtained five minutes after injection during a period between one and four weeks after fracture was found to be related to the incidence of non-union after six months. A ratio of 1.3 between the uptake at the fracture site and at normal bone adjacent to it predicted non-union in an individual patient with a sensitivity of about 70% and a specificity of 90%.
mesh_terms: D000293:Adolescent; D000328:Adult; D005599:Fractures, Ununited / Q000000981:diagnostic imaging; D006801:Humans; D008875:Middle Aged; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate; D013978:Tibial Fractures / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013997:Time Factors; D014945:Wound Healing
chemical_list: D013669:Technetium Tc 99m Medronate