title: Degradations of 4-cholesten-3-one and 1,4-androstadiene-3,17-dione by cholesterol-degrading bacteria.
abstract: Degradations of 4-cholesten-3-one and 1,4-androstadiene-3,17-dione, which are intermediates of microbial conversion of cholesterol, by cholesterol-degrading bacteria (12 strains of the genus Rhodococcus isolated from food of animal origin and 12 culture collection strains) were examined. All strains had the ability to degrade 4-cholesten-3-one without necessarily being able to degrade cholesterol. On the other hand, the bacteria were divided into three groups with little or no (0-10%), intermediate (10-70%) and high (70-100%) degradation abilities for 1,4-androstadiene-3,17-dione.
mesh_terms: D000730:Androstadienes / Q000378:metabolism*; D002782:Cholestenes / Q000378:metabolism*; D002783:Cholestenones / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism; D003352:Corynebacterium / Q000378:metabolism*; D009615:Nocardia / Q000378:metabolism*; D012240:Rhodococcus / Q000378:metabolism*
chemical_list: D000730:Androstadienes; D002782:Cholestenes; D002783:Cholestenones; C006573:1,4-androstadiene-3,17-dione; C000475:cholest-4-en-3-one; D002784:Cholesterol