Histologic changes in the dog acetabulum following total hip replacement with current cementing techniques.
Histologic changes in the acetabuli of adult dogs were studied following total hip replacement with current cementing techniques. Active bone remodeling was evident throughout the acetabulum by 2 weeks after operation and continued throughout the 6 months of the study, leading to considerable hypertrophy of the trabecular bone of the acetabulum. By 6 months after operation, a thick (average, 0.4 mm), fibrous membrane had formed at the bone-cement interface in 83 of 84 sections examined. Direct apposition of bone to cement was seen only within the 2-mm fixation holes. Formation of a fibrous membrane appears to be intrinsic to the cementing of the acetabular component, perhaps because geometry of the acetabulum precludes effective pressurization of the cement.
D000077:Acetabulum / Q000473:pathology*; D000818:Animals; D001843:Bone Cements / Q000008:administration & dosage*; D004285:Dogs; D006622:Hip Prosthesis; D011474:Prosthesis Design; D011475:Prosthesis Failure; D014945:Wound Healing / Q000187:drug effects
D001843:Bone Cements