[Biosynthesis of chromatin proteins in the thymocytes of irradiated rats].
Biosynthesis of chromatin proteins in thymus cells of irradiated rats has been studied. During the period immediately preceding DNA degradation, new proteins, which are not found in the chromatin of the control cells, are synthesized in the exposed thymocytes and enter the chromatin. Besides, the rate of biosynthesis of a large number of other chromatin proteins decreases. The data obtained indicate that interphase death of lymphoid cells is an active, genetically programmed process.
D000818:Animals; D002843:Chromatin / Q000378:metabolism / Q000528:radiation effects*; D004247:DNA / Q000378:metabolism / Q000528:radiation effects; D004591:Electrophoresis, Polyacrylamide Gel; D005720:Gamma Rays; D008297:Male; D011089:Polydeoxyribonucleotides / Q000032:analysis / Q000528:radiation effects; D014176:Protein Biosynthesis; D011506:Proteins / Q000032:analysis / Q000528:radiation effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors
D002843:Chromatin; D011089:Polydeoxyribonucleotides; D011506:Proteins; D004247:DNA
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