[Persistent acantholytic dermatosis with increased light sensitivity].
We report on a 72-year-old man suffering from transient acantholytic dermatosis (TAD). The histologic pattern resembled that of Darier's disease. The disorder first set on after an episode of intensive exposure to sunlight and persisted for 6 years. The only drug the patient took during this period was the prophylactic antimaterial preparation, Fansidar. His sensitivity to UVB radiation was markedly increased. After Fansidar was replaced by Resochin, the skin cleared up. After one year the sensitivity to UVB had normalized.
D000368:Aged; D001706:Biopsy; D004820:Epidermolysis Bullosa / Q000473:pathology*; D006801:Humans; D008297:Male; D010787:Photosensitivity Disorders / Q000473:pathology*; D012867:Skin / Q000473:pathology; D013472:Sunlight / Q000009:adverse effects*
Persistierende akantholytische Dermatose bei erhöhter Lichtempfindlichkeit.