title: Current results of esophageal cancer surgery. Time trends in operative mortality and long term survival.
abstract: This paper represents a historical analysis of the results achieved by esophageal cancer surgery over the last three decades, as they appear in the literature of the years 1954-1985, and in our own experience between 1965 and 1985, with the aim of assessing the evolution of operative mortality and long-term survival. In a review of 4930 resections reported in western literature, mean values of perioperative mortality went down from 30% to 9%, while the five-year survival increased from 8% to 19%. Similar changes were evident in Japanese and Chinese literature where the survival rose from 9% to 23% in unscreened populations and up to 90% in early cancers. In our experience, dividing the series in two decades (1965-74 and 1975-85), the overall perioperative mortality changed from 28% to 13%. The actuarial survival for the two periods was 8% vs 18% at 5 years, with a median survival of 9 and 18 months. A greater difference was evident for N0 patients where the survival rose from 15% to 35% at 5 years, with a median survival of 15 vs 38 months.
mesh_terms: D002681:China; D004938:Esophageal Neoplasms / Q000401:mortality* / Q000601:surgery; D004944:Esophagoplasty / Q000379:methods / Q000401:mortality*; D005060:Europe; D006801:Humans; D007558:Italy; D007564:Japan; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D013270:Stomach / Q000601:surgery; D013997:Time Factors