title: The management of aortoduodenal fistula by in situ replacement of the infected abdominal aortic graft.
abstract: Conventional surgical wisdom dictates the complete removal of infected abdominal aortic graft, oversewing of the aorta, and restoration of lower limb bloodflow by extra-anatomic bypass grafting. Dissatisfied with this approach because of the high incidence of local complications, mortality, and loss of limb, 20 patients with secondary aortoduodenal fistula had duodenal repair, excision of the old graft, and placement of a new graft in the same location. A similar technique was used in three patients with erosion of an aortic graft into the jejunum. Length of follow-up averaged 5.2 years, and was more than 1 year in each instance. Of the eighteen patients who survived the repair, three have had early recurrent rupture or false aneurysm of the proximal aortic anastomosis, with consequent death in two, but fifteen patients (83%) have had no further related problem. There was no loss of limb. Use of greater omentum as a protective barrier seemed helpful. Optimal antibiotic usage, and the idea that varying degrees of graft infection require different approaches, require further definition. In conclusion, in situ graft replacement is the correct operative strategy in this challenging group of patients.
mesh_terms: D001012:Aorta, Abdominal / Q000601:surgery*; D001018:Aortic Diseases / Q000209:etiology / Q000628:therapy*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D004378:Duodenal Diseases / Q000209:etiology / Q000628:therapy*; D005402:Fistula / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007239:Infections / Q000150:complications*; D007412:Intestinal Fistula / Q000209:etiology / Q000628:therapy*; D008722:Methods