Urinary excretion of cocaine and benzoylecgonine following oral ingestion in a single subject.
A 25 mg oral dose of cocaine HCl given to a single volunteer resulted in a peak urinary cocaine concentration of 269 ng/mL at 1 h, and a peak benzoylecgonine concentration of 7,940 ng/mL at 12 h. Urine benzoylecgonine concentrations remained in excess of 300 ng/mL for 48 h. We conclude that small, oral doses of cocaine, potentially undetectable to the user, may cause positive urine test results for at least 48 h using routine detection methods.
D000284:Administration, Oral; D000328:Adult; D003042:Cocaine / Q000031:analogs & derivatives* / Q000652:urine*; D006801:Humans; D008297:Male
C005618:benzoylecgonine; D003042:Cocaine