title: Photoperiodic modulation of cephalic melatonin in planarians.
abstract: Endogenous melatonin was detected by high-performance liquid chromatography (HPLC) with electrochemical detection (EC) in the head of the planarian Dugesia dorotocephala. The identity of this elution peak was further confirmed by radioimmunoassay. In groups of planarians adapted to either normal or reversed photoperiods, the melatonin levels were always higher in those heads collected in the dark period than in those collected in the light period. This indicates that primitive animals such as planarians have already evolved a melatonin-metabolizing system that is photically driven in a manner suggestive of the way melatonin synthesis is influenced by light and dark cycles in vertebrates.
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D008027:Light; D008550:Melatonin / Q000032:analysis / Q000378:metabolism*; D010507:Periodicity; D010932:Planarians / Q000032:analysis / Q000378:metabolism*; D014419:Turbellaria / Q000378:metabolism*
chemical_list: D008550:Melatonin