[Pharmacokinetics of ethonium administered perorally].
In experiments on rats it was shown that ethonium pharmacokinetics at intragastric administration may be described within the framework of the two-compartment model with absorption. After administration ethonium cannot be directly absorbed although its absorption proceeds rapidly. The distribution between the central and peripheral compartments is slowed as well as the process of elimination from the blood flow.
D000042:Absorption; D000284:Administration, Oral; D000818:Animals; D000890:Anti-Infective Agents / Q000378:metabolism*; D001682:Biological Availability; D007700:Kinetics; D008297:Male; D008433:Mathematics; D000644:Quaternary Ammonium Compounds / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D000890:Anti-Infective Agents; D000644:Quaternary Ammonium Compounds; C004921:Ethonium
Farmakokinetika étoniia pri peroral'nom vvedenii.