Efficacy and tolerance of fenticonazole versus miconazole cream.
On the basis of a randomized scheme, 40 patients affected by pityriasis versicolor, candidiasis or dermatophytosis were treated with fenticonazole 2% cream or with miconazole 2% cream. Clinical healing was obtained in 16 patients and there were four improvements in those treated with fenticonazole. In those treated with miconazole there were 14 clinically healed and five improvements. Only in two cases treated with miconazole and in one with fenticonazole, microscopic and cultural analysis had not become negative by the end of treatment. Both drugs were well tolerated. At the end of the study it was concluded that fenticonazole 2% cream is an effective antimycotic with an equal or even higher activity than miconazole.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy; D002648:Child; D003881:Dermatomycoses / Q000188:drug therapy*; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008825:Miconazole / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D009824:Ointments; D014010:Tinea Versicolor / Q000188:drug therapy
D000935:Antifungal Agents; D007093:Imidazoles; D009824:Ointments; D008825:Miconazole; C033486:fenticonazole