Rapid disappearance from the intestinal tract of bacteria resistant to rifaximin.
The appearance in the faeces of resistant bacteria after oral treatment with Rifaximin, a new, non-absorbable rifamycin derivative, was investigated. To evaluate the degree of colonization of the intestinal tract by the Rifaximin-resistant strains, long-term bacteriological monitoring of the faeces of drug-treated volunteers was carried out. The data obtained showed that after suspension of treatment the resistant bacteria disappeared rapidly.
D001419:Bacteria / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D012294:Rifamycins / Q000494:pharmacology*; D000078262:Rifaximin
D012294:Rifamycins; D000078262:Rifaximin