Rhabdomyolysis following violent behavior and coma.
An individual suspected of being under the influence of phencyclidine (PCP) exhibited acute psychotic and violent behavior which was followed by cardiac arrest, coma, and renal failure. Sections of the damaged muscle showed rhabdomyolysis, and sections of the kidneys showed myoglonin casts positive for immunoperoxidase stain. Extensive toxicology studies for narcotics, PCP, and cocaine were negative. Therefore, a correlation between PCP and rhabdomyolysis associated with acute psychotic and violent behavior could not be made with certainty. The etiology and pathogenesis of rhabdomyolysis are discussed in depth.
D000328:Adult; D003128:Coma / Q000150:complications*; D003617:Dangerous Behavior; D006801:Humans; D008297:Male; D012206:Rhabdomyolysis / Q000209:etiology* / Q000473:pathology; D014754:Violence