Bladder cancer detection and surveillance: carcinoembryonic antigen as a monitor of neoplastic transformation.
Routine cytopathology of exfoliated urothelial cells will identify only 70% of patients with transitional cell carcinoma (TCC) because most well-differentiated bladder tumors are not detected. Carcinoembryonic antigen (CEA) was identified on urothelial cancer cells from 66% of patients with grade I TCC, 65% with grade II TCC, 65% with grade III TCC, and 80% of patients with CIS. Immunoperoxidase labelling of CEA can enhance the sensitivity of exfoliative cytology.
D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis*; D003581:Cytodiagnosis; D006801:Humans; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*
D002272:Carcinoembryonic Antigen