Induction of 2',5'oligo (A) synthetase in animals bearing Ehrlich ascites tumor cells.
The activity of 2',5'oligo(A) synthetase in experimental mice inoculated with poly(I) poly(C) is higher in the animals with transplantable tumors (Ehrlich Ascites Tumor cells) compared to animals without the tumor. The higher enzymatic activity is detected in tissue homogenates from liver and spleen, as well as in homogenates from the Ascites cells.
D015088:2',5'-Oligoadenylate Synthetase / Q000096:biosynthesis*; D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology*; D004790:Enzyme Induction; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D051379:Mice; D008805:Mice, Inbred A; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D011070:Poly I-C / Q000494:pharmacology*; D013154:Spleen / Q000201:enzymology
D015088:2',5'-Oligoadenylate Synthetase; D011070:Poly I-C