Sample size and power for pair-matched case-control studies.
A new sample size formula is derived herein for matched-pair case-control studies. This result is based on an unconditional approach to the use of McNemar's statistic. We contrast this method for determining sample size and power with Schlesselman's conditional approach and compare the results numerically in a Monte Carlo study.
D001699:Biometry; D004812:Epidemiologic Methods; D006801:Humans; D009010:Monte Carlo Method