Hypertension induced by methyl mercury in rats.
Rats were treated with an acute dose of methylmercury chloride (5 mg/kg body wt/day) or with a chronical dose (0.5 mg/kg body wt/day). Measurements of systolic blood pressure by the tail-cuff method revealed that a long-lasting increase in SBP occurs in the chronically treated rats.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006973:Hypertension / Q000139:chemically induced*; D008297:Male; D008767:Methylmercury Compounds / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains
D008767:Methylmercury Compounds