Baboon (Papio ursinus) model to study deep vein thrombosis using 111-indium-labeled autologous platelets.
This study evaluates the chacma baboon as a model for investigations on deep vein thrombosis (DVT). There is a good correlation of the baboon and human thrombelastographic parameters (r-time, k-time, ma). Investigation on the diagnostic efficacy of 111 In-labeled platelets as an imaging agent for DVT cast considerable doubt on the procedure, owing to the age of the thrombus.
D000818:Animals; D001792:Blood Platelets; D004195:Disease Models, Animal; D005268:Femoral Vein / Q000000981:diagnostic imaging; D007204:Indium; D008297:Male; D010215:Papio; D011859:Radiography; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013927:Thrombosis / Q000000981:diagnostic imaging*; D013997:Time Factors
D011868:Radioisotopes; D007204:Indium