title: The effect of forced running on heat production in brown adipose tissue in rats.
abstract: The effect of running on heat production in brown adipose tissue (BAT) was compared between trained and untrained rats. Rats were forced to run a treadmill while temperatures of colon (T col) and interscapular BAT (T bat) were measured. The daily running for 5 weeks neither changed the size of interscapular BAT nor the norepinephrine-induced thermogenesis (8 micrograms/kg X min). During running, both T bat and T col increased. In rats trained for 2 weeks, the increases in T bat were similar to those in T col. In untrained rats, however, the increases in T bat were larger than those in T col. It is suggested that exercise increases heat production in BAT in untrained rats, but such heat production in BAT is abolished by daily exercise. Exercise suppresses cold-induced heat production in BAT of trained rats.
mesh_terms: D002001:Adipose Tissue, Brown / Q000033:anatomy & histology / Q000502:physiology*; D000818:Animals; D001833:Body Temperature Regulation; D001835:Body Weight; D006321:Heart / Q000033:anatomy & histology; D008297:Male; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D012420:Running; D014836:Volition