title: [Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure].
abstract: Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure. An equally marked additional lowering of pressure was achieved when patients who had been given guanethidine/dipivefrin over an extended period of time were additionally treated with one dose of pilocarpine 2%. The reduction in intraocular pressure was much more pronounced in patients who had been treated with pilocarpine 2% alone over an extended period of time, followed by a single dose of guanethidine/dipivefrin, than in those who had been treated first with guanethidine/dipivefrin and subsequently with pilocarpine.
mesh_terms: D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006145:Guanethidine / Q000627:therapeutic use*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D009798:Ocular Hypertension / Q000188:drug therapy*; D010862:Pilocarpine / Q000627:therapeutic use*
chemical_list: D010862:Pilocarpine; C015173:dipivefrin; D004837:Epinephrine; D006145:Guanethidine
vernacular_title: Guanethidin/Dipivefrin und Pilokarpin bei der Behandlung des erhöhten intraokularen Drucks.