[EEG analysis of the effect of stimulation of GABAergic structures of the caudate nucleus on the development of the effect of haloperidol].
Functional significance of GABA-structures of the caudate nucleus was studied by EEG analysis of the influence of stimulation of these structures on the development of the effect of systemic introduction of the blockader of dopaminergic receptors haloperidol. Microinjections of GABA to the caudate nucleus prevented the suppressing action of haloperidol on food-procuring cats behaviour and led to restoration of the EEG-reaction to conditioned sound stimuli. A conclusion is made about an important role of GABA-ergic structures in the mechanisms of dopaminergic control of the inhibitory function of the caudate nucleus.
D000818:Animals; D001931:Brain Mapping; D002415:Cats; D002421:Caudate Nucleus / Q000187:drug effects* / Q000502:physiology; D002799:Cholinergic Fibers / Q000502:physiology; D004298:Dopamine / Q000502:physiology; D004569:Electroencephalography; D005247:Feeding Behavior / Q000187:drug effects* / Q000502:physiology; D006220:Haloperidol / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
D005680:gamma-Aminobutyric Acid; D006220:Haloperidol; D004298:Dopamine
EEG-analiz vliianiia stimuliatsii GAMKergicheskikh struktur khvostatogo iadra na razvitie éffekta galoperidola.