[Neurogenic cholinergic dilation observed in isolated vessels of the skeletal muscles of cats (the caudal femoral artery)].
Neuromediated behaviour of feline caudal femoral arteries was studied in vitro. Transmural stimulation of arteries, previously constricted by noradrenaline, caused an up to 58% relaxation of the induced tone. Atropine (10(-5) g/ml) blocked this response by 93%. The removal of endothelium did not affect the magnitude of the response. It is suggested that the caudal femoral artery is an example of a blood vessel which has muscarinic receptors located directly on its smooth muscles.
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002415:Cats; D004558:Electric Stimulation; D005263:Femoral Artery / Q000187:drug effects / Q000294:innervation / Q000502:physiology; D006145:Guanethidine / Q000494:pharmacology; D066298:In Vitro Techniques; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000294:innervation / Q000502:physiology*; D009638:Norepinephrine / Q000494:pharmacology; D010477:Perfusion / Q000379:methods; D011796:Quinacrine / Q000494:pharmacology; D011950:Receptors, Cholinergic / Q000187:drug effects / Q000502:physiology*; D014664:Vasodilation / Q000187:drug effects
D011950:Receptors, Cholinergic; D001285:Atropine; D011796:Quinacrine; D009638:Norepinephrine; D006145:Guanethidine
Neĭrogennoe rasshirenie kholinergicheskoĭ prirody, nabliudaemoe v izolirovannykh sosudakh skeletnykh myshts koshki (kaudal'naia bedrennaia arteriia).