title: [Planned multidisciplinary approach in the treatment of advanced carcinoma of the tongue].
abstract: 16 patients with advanced lingual carcinoma treated by planned multidisciplinary treatment and postoperative reconstruction in our hospital from 1970 to 1984 are reported. The treatment included: preoperative chemotherapy of high dose MTX; extensive resection of the tongue with radical neck dissection and postoperative radiation. The immediate reconstruction was performed by using pedicled major pectoralis myocutaneous flap in 12 patients and free tensor fascia lata myocutaneous flap in 4. The 5 and 3 year survival rates of stage IV lesions were 50% and 100%. The advantages of the planned multidisciplinary treatment of advanced lingual cancer are discussed.
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage*; D008875:Middle Aged; D037981:Neck Dissection; D011182:Postoperative Care; D011292:Premedication; D013524:Surgical Flaps; D014062:Tongue Neoplasms / Q000532:radiotherapy / Q000628:therapy*
chemical_list: D008727:Methotrexate