[Factors linked to the development of pleuro-pulmonary metastases in breast cancer. Preliminary study].
The risk of death after pleuro-pulmonary metastasis was studied on a sample of 55 patients treated for breast cancer between 1954 and 1978. The women treated by tamoxifen, aminoglutethimide, or radiotherapeutic castration, at the time of the appearance of their metastasis, had a significantly lower risk of death than the women treated by other methods, or who were left untreated. The characteristics of the initial tumor, the delay between the primary tumor and the metastasis, the rhythm of systematic chest X-rays, and the use of chemotherapy did not significantly decrease this risk. The management of controlled therapeutic trials is suggested to confirm these results.
D000616:Aminoglutethimide / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000473:pathology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary*; D010997:Pleural Neoplasms / Q000517:prevention & control / Q000556:secondary*; D011379:Prognosis; D012306:Risk; D013629:Tamoxifen / Q000627:therapeutic use
D013629:Tamoxifen; D000616:Aminoglutethimide
Facteurs liés à l'évolution des métastases pleuro-pulmonaires dans le cancer du sein. Etude préliminaire.