Freeze-etching study of synaptosomes from rat cerebral cortex.
Synaptosomes from rat cerebral cortex were studied using the freeze-etching technique. The intra-membranous structure of the pre- and postsynaptic membranes was examined. Particles with an electron-dense spot on their apex are reported from all fracture faces. Most probably these are related to transmembrane channels whose significance in the synaptic transmission is discussed.
D000818:Animals; D002540:Cerebral Cortex / Q000648:ultrastructure*; D005260:Female; D005613:Freeze Etching; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains; D013570:Synaptic Membranes / Q000648:ultrastructure; D013574:Synaptosomes / Q000648:ultrastructure*