title: Interval estimation of the median lethal dose.
abstract: Assuming a logistic dose-response curve, one can construct a confidence interval for the LD50 from the asymptotic likelihood ratio test. Reasons are given for preferring this likelihood ratio interval to the established interval calculated by applying Fieller's theorem to the maximum likelihood estimates.
mesh_terms: D000818:Animals; D001699:Biometry; D004305:Dose-Response Relationship, Drug; D007928:Lethal Dose 50