Clinical results in the treatment of therapy-resistant calcium-stone formers with non-steroidal anti-inflammatory drugs.
Long-lasting success was obtained in the treatment of 8 therapy-resistant, frequently relapsing calcium-stone formers with non-steroidal anti-inflammatory drugs (NSAIDs). Over the period of treatment the rate of stone formation decreased markedly in these patients. Until now 3 test persons have exhibited only partial success with NSAID treatment. Diclofenac-Na as single-drug therapy or in combination with thiazide preparations or indomethacin is presented as a novel therapeutic possibility, the influence of NSAID on pathomechanism of calcium-stone formation is discussed.
D000328:Adult; D000368:Aged; D002129:Calcium Oxalate / Q000032:analysis; D004008:Diclofenac / Q000009:adverse effects / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014545:Urinary Calculi / Q000032:analysis / Q000188:drug therapy*
D004008:Diclofenac; D002129:Calcium Oxalate; D007213:Indomethacin