title: Clinical manifestations of secondary syphilis.
abstract: The results of a prospective study, aimed at having a fresh look at the clinical features of secondary syphilis in 89 patients, are presented. Eighty-one (91.0%) had syphilides, and of these, 24 (29.6%) had atypical morphology. Two or more groups of lymph nodes were enlarged in 60, and hepatosplenomegaly was seen in 20 (22.5%) patients. Condylomata data in atypical sites occurred in six patients. A total of 10 patients had alopecia on the scalp, and anterior uveitis was seen in 7 (7.9%). The clear CSF showed minimal elevation of lymphocytes in one of the 21 patients on whom lumbar puncture was performed and may, therefore, be considered unnecessary as a routine procedure. An awareness of the varied clinical presentations would assist in early diagnosis of the disease and help reduce its complications.
mesh_terms: D000328:Adult; D000505:Alopecia / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D011446:Prospective Studies; D012867:Skin / Q000473:pathology; D013587:Syphilis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D013591:Syphilis, Cutaneous / Q000175:diagnosis* / Q000473:pathology; D014606:Uveitis, Anterior / Q000209:etiology
chemical_list: D010401:Penicillin G Benzathine