Ectrodactyly in sisters and half sisters.
An extended family is described in which four sisters and half sisters presented with ectrodactyly. Two of the sisters had associated agenesis of the tibiae. The paper describes the malformations and discusses the management and possible genetic inheritance involved. An autosomal recessive gene seems likely to be the mode of inheritance.
D000015:Abnormalities, Multiple / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D005260:Female; D005808:Genes, Recessive; D006228:Hand Deformities, Congenital; D006801:Humans; D007223:Infant; D007866:Leg / Q000002:abnormalities*; D010375:Pedigree