title: Cannulation of the portal vein for cytotoxic liver perfusion in colorectal carcinomas: an alternative approach.
abstract: Cytotoxic liver perfusion via the portal vein has been used with some success as an adjuvant to surgery for colorectal carcinoma. We have used an alternative method of cannulating the portal vein at the time of operation and support the use of this method as well as the use of short-term 5FU infusion via the portal vein as being safe and of low systemic toxicity.
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002404:Catheterization / Q000379:methods*; D003110:Colonic Neoplasms / Q000601:surgery; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D011169:Portal Vein; D011741:Pyrimidine Nucleosides / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents; D011741:Pyrimidine Nucleosides; C027266:5-fluorouracil glucuronide; D005472:Fluorouracil