title: Hippocampal lesions and trace conditioning in the rabbit.
abstract: Trace conditioning of the nictitating membrane response (NMR) was examined in rabbits with lesions of the dorsal hippocampus and fimbria-fornix. Using a white noise conditional stimulus and an electrical shock unconditional stimulus, the number and amplitude of conditional responses (CRs) was similar in hippocampus-lesioned and control subjects. At some stages of conditioning, the latencies of CRs from hippocampus-lesioned subjects were slightly shorter than those of the controls. We suggest that the hippocampus is not essential for trace conditioning but may exert a modulatory influence on the timing of the CR.
mesh_terms: D000818:Animals; D001931:Brain Mapping; D003215:Conditioning, Eyelid / Q000502:physiology*; D003463:Cues; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D011817:Rabbits; D011930:Reaction Time / Q000502:physiology