A histologic evaluation of the effects of skin refrigerants in an animal model.
The effects of a number of commonly used skin refrigerants were studied in controlled freezing experiments on guinea pig skin. Frigiderm and Fluro Ethyl produced very little effect on the skin compared to colder preparations such as Cryosthesia -30 degrees C and Cryosthesia -60 degrees C.
D000818:Animals; D001706:Biopsy; D005617:Chlorofluorocarbons, Methane / Q000009:adverse effects*; D003869:Dermabrasion; D004353:Drug Evaluation, Preclinical; D005615:Freezing; D006168:Guinea Pigs; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D013997:Time Factors
D005617:Chlorofluorocarbons, Methane