[Synthesis of 1-(1-alkenyl)-2-acetyl-sn-glycero-3-phosphocholines, the aldehyded analogs of platelet activating factor].
1-(1-Hexadecenyl)- and 1-(1-octadecenyl)-2-acetyl-sn-glycero-3-phosphocholines were synthesized. To this goal, synthetically prepared racemic phosphatidal-cholines were hydrolyzed with phospholipase A2, and lysophosphatidal-cholines obtained were acetylated with acetic anhydride.
D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D066298:In Vitro Techniques; D010972:Platelet Activating Factor / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D010974:Platelet Aggregation / Q000187:drug effects
D010972:Platelet Activating Factor; C037145:1-hexadecyl-2-acetyl-glycero-3-phosphocholine; C026613:1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine
Sintez 1-(1-alkenil)-2-atsetil-sn-glitsero-3-fosfokholinov, al'degirovannykh analogov faktora aktivatsii trombotsitov.