title: A case of association between type I hyperlipoproteinemia and systemic lupus erythematosus (SLE). Effects of steroid treatment.
abstract: The case of a girl aged 19 yr with hypertriglyceridemia and systemic lupus erythematosus (SLE) is described. The girl had been admitted to a Lipid Outpatient Clinic in 1981 and diagnosed as having a Type I hyperlipidemia pattern. In November 1984 the patient acutely developed a SLE syndrome. Steroid treatment led to a dramatic fall of serum triglycerides from a starting value of 2100 mg/dl to 95 mg/dl. The role of steroids in completely correcting genetically deficient Lipoprotein Lipase Activity (LLA) is discussed.
mesh_terms: D000328:Adult; D001053:Apolipoproteins / Q000097:blood; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D008072:Hyperlipoproteinemia Type I / Q000150:complications* / Q000235:genetics; D006951:Hyperlipoproteinemias / Q000150:complications*; D008071:Lipoprotein Lipase / Q000378:metabolism; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D013256:Steroids / Q000627:therapeutic use*
chemical_list: D001053:Apolipoproteins; D013256:Steroids; D002784:Cholesterol; D008071:Lipoprotein Lipase