[Severe ocular toxicity of desferrioxamine in the hemodialyzed patient].
Severe and persistent visual loss with retinitis pigmentosa occurred in a hemodialyzed patient, treated with desferrioxamine (DFO) for aluminium intoxication, with a total DFO dose of 18 g given over 9 weeks. Cases reported since 1983 are reviewed, and hypothesis and risk factors for DFO toxicity are discussed. Caution should be exercised in using DFO in hemodialyzed patients.
D000368:Aged; D000535:Aluminum / Q000506:poisoning; D003676:Deferoxamine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D006435:Renal Dialysis / Q000009:adverse effects; D012174:Retinitis Pigmentosa / Q000139:chemically induced*; D014786:Vision Disorders / Q000139:chemically induced*
D000535:Aluminum; D003676:Deferoxamine
Toxicité oculaire sévère de la desferrioxamine chez l'hémodialysé.