Plasma fibronectin levels during daily plasmapheresis.
Plasma fibronectin concentrations were studied in 10 patients with multiple myeloma. After plasma exchange for 3 d (2.5-3 l plasma daily) the plasma fibronectin decreased to about 50% of the initial level. Resynthesis of fibronectin seemed to increase during 3 d of plasmapheresis, and was sufficient to normalize plasma fibronectin concentration. The plasma fibronectin concentration reached the initial level within 2 d after interrupting plasmapheresis in spite of concurrent cytotoxic treatment. The patients studied showed no signs of infection.
D005353:Fibronectins / Q000097:blood*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D009101:Multiple Myeloma / Q000097:blood / Q000628:therapy; D010956:Plasmapheresis; D013997:Time Factors
D005353:Fibronectins; D007074:Immunoglobulin G