[Effect of hyperbaric oxygenation on free-radical processes and gastric acid production in patients with duodenal ulcer].
Ascorbate- and NADPH-dependent free radical oxidation, the state of the antioxidant system, hydrogen iron secretion rate (HISR) and acid production kinetic function (AFKF) were investigated in 38 patients with duodenal ulcer to study the effect of hyperbaric oxygenation on free radical processes and gastric acid production. Assessment of the results of the study indicated the activation of NADPH-dependent free radical lipid oxidation, HISR acceleration and AFKF enhancement during hyperbaric oxygenation in the treatment of duodenal ulcer which required adjuvant corrective therapy.
D000328:Adult; D000863:Antacids / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004381:Duodenal Ulcer / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005609:Free Radicals; D005744:Gastric Acid / Q000378:metabolism*; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000009:adverse effects*; D008054:Lipid Peroxides / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D008297:Male; D008875:Middle Aged
D000863:Antacids; D000975:Antioxidants; D005609:Free Radicals; D008054:Lipid Peroxides
Vliianie giperbaricheskoĭ oksigenatsii na svobodno-radikal'nye protsessy i zheludochnoe kislotoobrazovanie u bol'nykh iazvennoĭ bolezn'iu dvenadtsatiperstnoĭ kishki.