Molecular aspects of allergic contact dermatitis to plants. Recent progress in phytodermatochemistry.
A classification of plants based on the chemical structures of their skin sensitizers is presented. A whole range of chemical structures of contact sensitizers exists in plants containing sesquiterpene lactones (Compositae, Frullania, Lauraceae etc.), tulipalin (Tulipa, Alstroemeria etc.), quinones (Primula and tropical woods), long chain phenols (Anacardiaceae, Ginkgoaceae) and miscellaneous structures such as aldehydes, ketones, terpene hydrocarbons etc. Knowledge of allergens in various plants allows prediction of cross-reactivity.
D000485:Allergens / Q000032:analysis; D003876:Dermatitis, Atopic / Q000209:etiology; D003877:Dermatitis, Contact / Q000209:etiology*; D006801:Humans; D007783:Lactones / Q000032:analysis; D010939:Plant Poisoning / Q000209:etiology*; D010947:Plants, Toxic / Q000032:analysis; D011809:Quinones / Q000032:analysis; D012717:Sesquiterpenes / Q000032:analysis; D013329:Structure-Activity Relationship
D000485:Allergens; D007783:Lactones; D011809:Quinones; D012717:Sesquiterpenes