title: [Effect of the high molecular weight fraction of non-collagenous bone tissue protein on osteogenesis and hematopoiesis in experimental elongation of an extremity].
abstract: High molecular fraction of HCl-extract from mature homologous bone was parenterally administered, during the predistraction period, into 16 rabbits, crus of which was elongated by Ilizarov procedure. The treatment affected positively the adaptation process, hemopoiesis and the ossification of distraction regenerate. Administration of the high molecular protein fraction into mice with depressed hemopoiesis demonstrated that physiological effect of the fraction consisted in stimulating effect on proliferation of both bone tissue and red blood cells.
mesh_terms: D000818:Animals; D001772:Blood Cell Count; D001852:Bone Lengthening / Q000379:methods*; D001857:Bone Matrix / Q000032:analysis / Q000502:physiology*; D006410:Hematopoiesis; D051379:Mice; D008970:Molecular Weight; D010012:Osteogenesis; D011506:Proteins / Q000032:analysis / Q000502:physiology*; D011817:Rabbits; D014020:Tissue Extracts / Q000494:pharmacology
chemical_list: D011506:Proteins; D014020:Tissue Extracts
vernacular_title: Vliianie vysokomolekuliarnoĭ fraktsii nekollagenovogo belka kostnoĭ tkani na osteogenez i krovetvorenie pri udlinenii konechnosti v éksperimente.