[Changes in the proliferative activity of cells from lymphoid organs of tumor-bearing mice after immunization with antitumoral vaccines].
The level of proliferative activity is studied in the cells of thymus, spleen and lymphoid nodes of mice with transplanted OH-2 tumour once- or thrice-immunized with vaccines from syngeneic tumour cells. Single immunization is shown to induce the short-term modulation of the proliferative processes in lymphoid organs and to increase somewhat the level of antitumour resistance of vaccinized mice. The triple-inoculation of vaccines evokes a more pronounced rise in the level of the proliferative activity in cells of lymphoid organs.
D000818:Animals; D002455:Cell Division; D008221:Lymphoid Tissue / Q000473:pathology*; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000276:immunology / Q000473:pathology* / Q000628:therapy; D014611:Vaccination; D014612:Vaccines / Q000008:administration & dosage*
D014612:Vaccines
Izmeneniia proliferativnoĭ aktivnosti kletok limfoidnykh organov mysheĭ s opukhol'iu pri immunizatsii protivoopukholevymi vaktsinami.