title: [Prevention and therapy of accidental radionuclide uptake].
abstract: After accidental incorporation of radionuclides in the organism uptake in the whole-body and in critical organs can be either reduced or blocked (prevention) by appropriate medication and behaviour. Effective half-lives after incorporation in critical organs can be shortened (therapy). For different fallout-radionuclides a variety of preparations exists for such purposes. For large-scale prevention only iodine administration seems appropriate to block the uptake of the generally occurring 131-I in the thyroid. Such an iodine prophylaxis, however, seems only necessary when drinking water concentrations exceed 5000 nCi/l. Excessive amounts of iodine can influence thyroid function significantly.
mesh_terms: D000059:Accidents; D000398:Air Pollution, Radioactive / Q000009:adverse effects; D002588:Cesium Radioisotopes / Q000009:adverse effects; D006207:Half-Life; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects; D011832:Radiation Injuries / Q000628:therapy*; D011879:Radiotherapy Dosage; D013326:Strontium Radioisotopes / Q000009:adverse effects; D013961:Thyroid Gland / Q000528:radiation effects
chemical_list: D002588:Cesium Radioisotopes; D007457:Iodine Radioisotopes; D013326:Strontium Radioisotopes
vernacular_title: Prävention und Therapie akzidenteller Inkorporation.