[Immunoallergic tubulo-interstitial nephritis following ingestion of carbamazepine].
One month after taking carbamazepine for pain relief, a 13 year-old child with Friedrich's ataxia presented with an allergic rash and digestive and cardiac symptoms. Two weeks later, non-oliguric renal failure suggestive of interstitial nephritis was present. Acute renal failure resolved with pulse methyl prednisolone injections relayed with prednisone orally, for 2 months. Allergic manifestations with carbamazepine should lead to immediate withdrawal of treatment.
D000293:Adolescent; D002220:Carbamazepine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D009207:Myoclonus / Q000188:drug therapy; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use
D002220:Carbamazepine; D011239:Prednisolone; D008775:Methylprednisolone
Néphrite tubulo-interstitielle immuno-allergique secondaire à la prise de carbamazépine.