title: Detraining of exercise-trained rats: effects on energetic efficiency and brown adipose tissue thermogenesis.
abstract: Complete energy balance measurements were made in exercise-trained (treadmill running) rats subjected to 27 d of exercise detraining. The 20% difference in body-weight that existed at the end of the training period between sedentary and trained rats was negated by detraining. Detrained rats had twice the body-weight gain of their untrained controls. An elevation (12%) in metabolizable energy (ME) intake (relative to body-weight) was observed in detrained rats while their gross energetic efficiency was augmented by 60%. Energy expenditure, excluding the estimated costs of fat and protein storage, was similar for detrained and untrained rats. Complementing the latter was the finding that thermogenesis in brown adipose tissue, a known energy buffering process, was also similar. Elevated ME intake (relative to body-weight) largely contributed to the increased energetic efficiency of detrained rats.
mesh_terms: D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D001833:Body Temperature Regulation; D001835:Body Weight; D004435:Eating; D004734:Energy Metabolism; D006153:Guanosine Diphosphate / Q000378:metabolism; D050356:Lipid Metabolism; D008297:Male; D005082:Physical Exertion; D011506:Proteins / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D011506:Proteins; D006153:Guanosine Diphosphate