title: Volume correction factor in time dose relationships in brachytherapy.
abstract: Paterson's clinical data about the maximum tolerance doses for various volumes of interstitial implants with Ra-226 delivered in seven days was made use of in deriving volume correction factors phi v and phi'v for TDF and CRE concepts respectively for brachytherapy. The derived volume correction factors phi v for TDF and phi'v for CRE differ from the from the one assumed for CRE by Kirk et al. and implied for TDF by Goitein. A normalising volume of 70 cc has been suggested for both CRE and TDF concepts for brachytherapy. A table showing TDFv, the volume corrected TDF, is presented for various volumes and dose rates for continuous irradiation. The use of this table is illustrated with examples.
mesh_terms: D001918:Brachytherapy / Q000379:methods*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy*; D011874:Radiometry / Q000379:methods*; D011879:Radiotherapy Dosage; D011883:Radium / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D011883:Radium