Effect of chronic ethanol treatment on peroxisomal acyl-CoA oxidase activity and lipid peroxidation in rat liver and heart.
Chronic ethanol administration was shown to increase catalase and acyl-CoA oxidase activities in rat myocardium but did not alter the activity of liver peroxisomal enzymes. As a result of alcohol consumption a 2-3-fold increase in the level of lipid peroxidation was observed in the heart tissue while in the liver the induction was much less pronounced.
D000437:Alcoholism / Q000378:metabolism*; D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D044943:Fatty Acid Desaturases / Q000378:metabolism*; D006321:Heart / Q000187:drug effects; D007700:Kinetics; D008054:Lipid Peroxides / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008830:Microbodies / Q000187:drug effects / Q000201:enzymology*; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D008054:Lipid Peroxides; D000431:Ethanol; D044943:Fatty Acid Desaturases