title: [Oxyurid infestation of small laboratory animals and its control with ivermectin].
abstract: Investigations on parasitic infestations in laboratory animal stocks under different keeping conditions were carried out by fecal sample examination. Only barrier-kept mice and rats proved to be free of infections. Under semi-open or conventionally keeping conditions mice were infected with Aspiculuris tetraptera and Syphacia obvelata (max. 94.7 + 69.7%), rats with A. tetraptera and S. muris (48.6 + 94.9%), and hamsters and mongolian jirds with S. obvelata (26.6 and 16%, respectively). Ivermectin, added to the drinking water for the elimination of murine oxyurids, over a 24-hour period, in a dosage of 1.0 (males) and 1.6 mg/kg body weight (females), proved to be highly effective against A. tetraptera; the treatment of S. obvelata-infections requires a dosage correction.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000830:Animals, Laboratory; D006224:Cricetinae; D005243:Feces / Q000469:parasitology; D005260:Female; D005849:Gerbillinae; D007559:Ivermectin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D051379:Mice; D010123:Oxyuriasis / Q000188:drug therapy / Q000662:veterinary*; D010124:Oxyuroidea / Q000187:drug effects / Q000302:isolation & purification; D051381:Rats; D012376:Rodent Diseases / Q000188:drug therapy*
chemical_list: D007559:Ivermectin
vernacular_title: Zum Oxyurenbefall kleiner Labortiere und seiner Bekämpfung mit Ivermectin.