title: [Teratologic studies on a low-molecular polyvinylpyrrolidone-iodine complex in rabbits].
abstract: In investigations on rabbits a low-molecular polyvinylpyrrolidone-iodine complex was tested upon its facultative teratological effects after intramuscular application. The dams showed a dose dependent loss of weight increase. The average embryo- and placenta weights of test animals were lower than those of the control animals. Some malformations in kidneys were realised, but they did not show any relation to dosage. Concerning the applied doses no teratological effect was observed.
mesh_terms: D000818:Animals; D004622:Embryo, Mammalian / Q000187:drug effects; D005260:Female; D009929:Organ Size / Q000187:drug effects; D010920:Placenta / Q000187:drug effects; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000633:toxicity*; D011247:Pregnancy; D011817:Rabbits; D013723:Teratogens
chemical_list: D013723:Teratogens; D011206:Povidone-Iodine; D011205:Povidone
vernacular_title: Teratologische Untersuchungen eines niedermolekularen Polyvinylpyrrolidon-Jod-Komplexes an Kaninchen.