Synthesis of neuropeptide Y.
Neuropeptide Y (NPY), a hexatriacontapeptide amide, was synthesized on benzhydrylamine resin. The peptide product obtained by HF treatment contained 63% of the target peptide, NPY. A comparison of the chemical, immunochemical and biological properties of the synthetic peptide with natural NPY indicated that they were identical.
D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D007202:Indicators and Reagents; D009478:Neuropeptide Y / Q000138:chemical synthesis*; D010446:Peptide Fragments / Q000032:analysis; D014357:Trypsin
D007202:Indicators and Reagents; D009478:Neuropeptide Y; D010446:Peptide Fragments; D014357:Trypsin