title: Degradation of polypropylene in the human eye: a SEM-study.
abstract: A polypropylene surgical suture, which had served as fixation suture for an IOL for a period of 6.5 years, was removed from the eye of a Dutch patient because it had broken at one end and thus formed a potential risk for a corneal touch syndrome. After careful rinsing in 50% ethanol, to remove adhering debris, it was prepared for SEM. A virgin piece of polypropylene material from a surgical package underwent the same preparative procedure. The fixation suture showed cracks perpendicular to the longitudinal axis of the suture; part of the surface layer was nearly detached or completely missing; while the diameter of the suture was decreased towards both ends by over 50% in comparison with the original diameter. The exposed subsurface layer showed a fibrillar structure. The degradation phenomena are considered to be caused by the enzymatic action of tissue-fluids. Virgin material did not show any of the phenomena observed on the fixation suture under consideration.
mesh_terms: D005123:Eye / Q000378:metabolism* / Q000648:ultrastructure; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010969:Plastics / Q000378:metabolism*; D011126:Polypropylenes / Q000378:metabolism*; D013537:Sutures; D013997:Time Factors
chemical_list: D010969:Plastics; D011126:Polypropylenes