Physostigmine improves ECT-induced memory disturbances.
Electroconvulsive therapy (ECT) induces transient confusion and amnesia. Using a double-blind crossover method we studied the influence of physostigmine on ECT-induced memory disturbances. We found that physostigmine reverse the impairment of verbal and visual short- and long-term memory after ECT. Immediate recall was neither impaired by ECT nor improved by physostigmine.
D000293:Adolescent; D000328:Adult; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000139:chemically induced / Q000188:drug therapy*; D008875:Middle Aged; D010830:Physostigmine / Q000627:therapeutic use*
D010830:Physostigmine