title: [Evaluation of the effect of ovariectomy in patients with stage III breast cancer].
abstract: The efficiency of prophylactic ovariectomy and hormone treatment with corticosteroids in patients with primary III degree breast carcinoma was studied. The indices of actuarial survival in the group of patients subjected to ovariectomy (n-115) during the follow-up period from 4 to 15 years proved to be reliably higher (p less than 0.05) as compared with controls (n-145). In determining the upper age limit of the susceptibility to ovariectomy it is expedient to take into consideration the menstrual status: in women it should be performed in premenopause or in the menopause not longer than 5 years.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008593:Menopause; D008875:Middle Aged; D009367:Neoplasm Staging; D010052:Ovariectomy; D011182:Postoperative Care; D012189:Retrospective Studies
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Otsenka éffekta ovariéktomii u bol'nykh rakom molochnoĭ zhelezy III stadii.