Diminution of postprandial release of pancreatic polypeptide in myotonic dystrophy.
The meal-stimulated release of pancreatic polypeptide (PP), gastrin, somatostatin and glucagon was studied in nine patients with myotonic dystrophy (MD) and in 11 healthy controls. PP-release was significantly reduced in MD compared to controls. This reduction may be related to the abnormal gut motility demonstrated in MD. The release of gastrin, somatostatin and glucagon was not significantly different in the two groups.
D000293:Adolescent; D000328:Adult; D005260:Female; D005502:Food; D006801:Humans; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000503:physiopathology*; D010191:Pancreatic Polypeptide / Q000378:metabolism*
D010191:Pancreatic Polypeptide