title: Studies of poly(ether)urethane pacemaker lead insulation oxidation.
abstract: Published reports suggest that silver ions may catalyze the oxidation of poly(ether)urethane soft-segments resulting in the failure of urethane insulations of specific models of pacemaker leads. Attempted oxidation of soft-segment models, poly(tetra-methylene ether)glycols, by silver nitrate has shown that metal-ion catalyzed oxidative-reduction (MICOR) does not adequately explain observed failures unless antioxidants are removed in process. Such cracking can, however, be explained in terms of a metal ion enhanced environmental stress cracking.
mesh_terms: D001672:Biocompatible Materials; D004868:Equipment Failure; D006861:Hydrogen Peroxide; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D010138:Pacemaker, Artificial; D011140:Polyurethanes; D012835:Silver Nitrate; D013055:Spectrophotometry, Infrared
chemical_list: D001672:Biocompatible Materials; D011140:Polyurethanes; C115016:polyetherurethane; D012835:Silver Nitrate; D006861:Hydrogen Peroxide