Species variations amongst proteinases in liver lysosomes.
Cathepsin B, H, L and D activities in liver lysosomes were compared between species. Although cathepsin B and D were detected in bovine, pig, chicken and rat liver, striking species differences were evident for cathepsin H and L. Cathepsin L activity was particularly high in chicken lysosomal extracts, but could not be detected in bovine and pig extracts. Whereas there was no significant cathepsin H activity in bovine extracts, rat liver lysosomal extracts contained large amounts of cathepsin H activity.
D000818:Animals; D002403:Cathepsins / Q000032:analysis*; D002417:Cattle / Q000378:metabolism; D002645:Chickens / Q000378:metabolism; D005260:Female; D008099:Liver / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology*; D051381:Rats / Q000378:metabolism; D013045:Species Specificity; D013552:Swine / Q000378:metabolism
D002403:Cathepsins