Evaluation of lannate 20, a carbamate pesticide in the germ cells of male mice.
Lannate 20, a carbamate pesticide, was evaluated for its effects on the germ cells of Swiss albino male mice, by the sperm morphology assay and meiotic chromosome preparations. The three sublethal concentrations of 20, 40, and 60 mg/kg body wt administered by the oral intubation method produced significant results (P less than 0.01) with both the above protocols in the said test system under study, thus indicating that lannate 20 is mutagenic in mice.
D000818:Animals; D002869:Chromosome Aberrations; D004305:Dose-Response Relationship, Drug; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D008724:Methomyl / Q000633:toxicity*; D051379:Mice; D013094:Spermatozoa / Q000187:drug effects*
D007306:Insecticides; D008724:Methomyl