title: [Analysis of hypotheses and simulation of selection for a suppressor affecting the manifestations of the fused gene in mice].
abstract: The t12 haplotype decreases sharply manifestation of fused gene in mice. The selection for increasing the penetrance of fused gene was made in Fu/t12 stock. The different computer models of selection process were compared. The hypothesis giving the best coincidence with experimental data supposes the presence of a semidominant gene suppressing the effect of t12 on Fu gene in chromosome 8.
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics*; D008957:Models, Genetic; D012641:Selection, Genetic; D012984:Software; D013489:Suppression, Genetic
vernacular_title: Analiz gipotez i modelirovanie otbora po supressoru, vliiaiushchemu na proiavlenie gena fused u mysheĭ.