Intravenous immunoglobulin in immune neutropenia.
Three patients with immune neutropenia successfully treated with high dose intravenous IgG (IV IgG) are described. In the first case, the neutropenia had not responded to standard steroid therapy; in the second case, very high doses of steroids were required in order to obtain and maintain remission. In the last case, the steroids were contraindicated because of an underlying immunologic disorder. We suggest that these 3 forms of immune neutropenia might be a good indication for IV IgG treatment.
D000293:Adolescent; D000380:Agranulocytosis / Q000628:therapy*; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000276:immunology / Q000628:therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007223:Infant; D008297:Male; D009503:Neutropenia / Q000276:immunology / Q000628:therapy*; D009504:Neutrophils / Q000276:immunology
D001323:Autoantibodies; D007074:Immunoglobulin G