Photochemotherapy of animal tumors with the photosensitizer methylene blue using a krypton laser.
The cytotoxic effect of the photosensitizer Methylene Blue activated with long wavelength laser radiation has been investigated using mice with solid Ehrlich carcinomas. A krypton laser was used as a light source emitting laser radiation at 647 nm and 676 nm. The red spectral range is important for photochemotherapy because it is easily transmitted through tissue. A significant tumor reduction, including complete tumor destruction, has been achieved.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000628:therapy*; D007726:Krypton; D053685:Laser Therapy; D008751:Methylene Blue / Q000627:therapeutic use*; D051379:Mice; D010789:Phototherapy
D007726:Krypton; D008751:Methylene Blue