Radical isotope surgery: an enrichment for the surgical therapy of gynecological malignancies.
Intraoperative lymphscintigraphy during radical isotope surgery was performed in 242 patients suffering from cervical cancer and 170 patients with breast carcinoma. The results show a decreased rate of recurrence mortality in cervical cancer stage I and a decreased rate of recurrencies and metastases in breast carcinoma. In ovarian cancer patients radiommunoscintigraphy was introduced in the diagnostic procedure and is now performed intraoperatively. The results show a high positive prediction value of 93%. In 5 out of 28 patients radioimmunoscintigraphy identified tumor regrowth while all other methods failed.
D000911:Antibodies, Monoclonal; D000965:Antimony; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D007457:Iodine Radioisotopes; D008197:Lymph Node Excision / Q000379:methods*; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging* / Q000601:surgery; D008722:Methods; D009364:Neoplasm Recurrence, Local; D011877:Radionuclide Imaging; D013667:Technetium; D017556:Technetium Compounds; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*
D000911:Antibodies, Monoclonal; D007457:Iodine Radioisotopes; D017556:Technetium Compounds; C019096:technetium Tc 99m antimony sulfide; D013667:Technetium; D000965:Antimony