title: [Value of the basophil degranulation test (BDT) in the follow-up of immunotherapy with hymenoptera venoms].
abstract: The basophil degranulation test (BDT) with the plasma of 24 patients undergoing venom immunotherapy was usually negative after only 6 months of treatment. Cellular sensitivity, however, could still be proved by BDT on purified cells, i.e. after removal of the plasma which contained blocking IgG antibodies. In 30% of the cases, we found primary desensitization of the basophils, which means that the IgG antibodies did not have any influence on the test results.
mesh_terms: D001491:Basophils / Q000276:immunology*; D001514:Bee Venoms / Q000276:immunology*; D003594:Cytoplasmic Granules / Q000276:immunology; D003888:Desensitization, Immunologic; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007299:Insect Bites and Stings / Q000276:immunology*
chemical_list: D001514:Bee Venoms; D007074:Immunoglobulin G; D007073:Immunoglobulin E
vernacular_title: Stellenwert des Basophilen-Degranulationstestes (BDT) als Verlaufskontrolle einer Immuntherapie mit Hymenopterengiften.