[Combination of heart myxoma with primary nodular adrenal cortex dysplasia. Case report of a further kinship of this rare familial syndrome].
Another case of the rare syndrome of combined papillary cardiac myxoma and primary adrenocortical nodular dysplasia is reported. The lesions were discovered incidentally at autopsy in a 64-year-old woman who had died of cerebrovascular stroke. Further investigation of the family by echocardiography revealed a small left atrial tumor in the 33-year-old son of the patient. Pathological examination after surgical resection of the tumor confirmed the diagnosis of atrial myxoma. The patient also exhibited cutaneous nodules with histologic features of myxofibroma. Some morphological aspects of this peculiar familial syndrome are discussed, with special emphasis on the finding of follicular tumors of the thyroid possibly associated with this syndrome.
D000230:Adenocarcinoma / Q000473:pathology; D000236:Adenoma / Q000473:pathology; D000302:Adrenal Cortex / Q000473:pathology; D000303:Adrenal Cortex Diseases / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology; D005260:Female; D006338:Heart Neoplasms / Q000235:genetics / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009232:Myxoma / Q000235:genetics / Q000473:pathology*; D013577:Syndrome; D013964:Thyroid Neoplasms / Q000473:pathology
Kombination von Herzmyxom mit primärer nodulärer Dysplasie der Nebennierenrinde.Beobachtung einer weiteren Sippe dieses eigenartigen familiären Syndroms.