title: [Value of karyotype in vascular acrosyndromes].
abstract: The evolution of Raynaud's phenomenon may, when clinical manifestations and capillaroscopy evoke the diagnosis of systemic disease, cause to consider performing a karyotype. In these cases, abnormalities are frequent, and 10% of these abnormalities must cause to suspect a collagen disease. The presence of the breaking factor is not the only etiology of these frequent abnormalities and a very thorough investigation must be made in order to rule out an extrinsic or idiopathic cause. Difficult to perform, it requires a highly specialized laboratory and demonstrates all its advantages in the etiological diagnosis of Raynaud's phenomenon.
mesh_terms: D002196:Capillaries / Q000473:pathology; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure*; D011928:Raynaud Disease / Q000175:diagnosis / Q000235:genetics*
vernacular_title: Intérêt du caryotype au cours des acrosyndromes vasculaires.