Increased CSF amino acids and ventricular enlargement in schizophrenia: a preliminary study.
We found significantly higher levels of cerebrospinal fluid alanine, glycine, leucine, and phenylalanine in schizophrenic patients compared to healthy controls. Ventricular enlargement was present in 4 of 11 schizophrenics, and elevated CSF alanine was highly correlated with ventricular enlargement. The implications of these findings are discussed.
D000328:Adult; D000596:Amino Acids / Q000134:cerebrospinal fluid*; D002552:Cerebral Ventricles / Q000473:pathology*; D003702:Delusions / Q000473:pathology; D005260:Female; D006212:Hallucinations / Q000473:pathology; D006801:Humans; D006984:Hypertrophy; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000134:cerebrospinal fluid / Q000473:pathology*; D012565:Schizophrenic Psychology; D014057:Tomography, X-Ray Computed
D000596:Amino Acids