title: Testicular swelling associated with desipramine.
abstract: Two cases of testicular swelling associated with desipramine therapy are described. In one case, the swelling resolved with discontinuation of desipramine; in the other, the swelling subsided despite continuation and an increase in dose. These cases may represent a local variant of angioneurotic edema; however, further study is required to determine the exact etiologic mechanism.
mesh_terms: D000328:Adult; D000799:Angioedema / Q000139:chemically induced; D003866:Depressive Disorder / Q000188:drug therapy; D003891:Desipramine / Q000009:adverse effects*; D004487:Edema / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013733:Testicular Diseases / Q000139:chemically induced*
chemical_list: D003891:Desipramine