Adenocarcinoma of the upper esophagus arising in ectopic gastric mucosa. Two case reports and review of the literature.
Although ectopic gastric mucosa is often mentioned as a source of upper esophageal adenocarcinoma, few such cases have actually been documented. We report two cases and offer a review of the literature. Ectopic gastric mucosa in the upper esophagus is a relatively common congenital condition, but the risk of malignant transformation is extremely low. Ectopic gastric mucosa should be distinguished from Barrett's esophagus, an acquired condition with a well-documented predilection for developing adenocarcinoma.
D000230:Adenocarcinoma / Q000601:surgery / Q000648:ultrastructure*; D002828:Choristoma / Q000648:ultrastructure*; D004938:Esophageal Neoplasms / Q000601:surgery / Q000648:ultrastructure*; D005753:Gastric Mucosa / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008875:Middle Aged