[Lymphocyte subpopulations in mesangial immunoglobulin A glomerulonephritis].
Lymphocyte subpopulations in peripheral blood were studied in 30 patients with IgA-glomerulonephritis and 24 healthy subjects via application of specific monoclonal antibodies. The following deviations were established: reduced number of OKT11 + cells (37.83 +/- 13.34, p less than 0.01): increased number of OKT8 + cells (25.89 +/- 6.70, p less than 0.01), no change in the number of OKM4 + cells, increased number of peripheral monocytes--OKM1 + cells (19.26 +/- 6.63, p less than 0.001). No significant correlations were established between the deviated parameters and arterial pressure, serum creatinine and serum IgA levels.
D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal; D005260:Female; D005920:Glomerular Mesangium / Q000276:immunology; D005922:Glomerulonephritis, IGA / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D000911:Antibodies, Monoclonal; D007070:Immunoglobulin A
Limfotsitni subpopulatsii pri mezangialen imunoglobulin-A-glomerulonefrit.