Comparative effect of certain organophosphorus compounds and other chemicals on whole blood, plasma and tissue cholinesterase activity in goats.
Cholinesterase (ChE) activity was measured in whole blood, plasma and certain tissues of goats experimentally poisoned with certain organophosphates, organochlorines, heavy metals and anthelmintic drugs. The enzyme activity was only inhibited by the organophosphorus compounds and not by any of the other substances used. The greatest inhibition occurred in the brain, although the blood ChE activity was concurrently inhibited in a similar degree.
D000818:Animals; D000871:Anthelmintics / Q000506:poisoning; D001921:Brain / Q000201:enzymology; D002800:Cholinesterase Inhibitors; D006041:Goats / Q000097:blood / Q000378:metabolism*; D007306:Insecticides / Q000506:poisoning; D008297:Male; D008670:Metals / Q000506:poisoning; D062025:Organophosphate Poisoning
D000871:Anthelmintics; D002800:Cholinesterase Inhibitors; D007306:Insecticides; D008670:Metals