title: Liver function tests during treatment with desipramine in children and adolescents.
abstract: Results of liver function tests in 42 children and adolescents treated with desipramine for up to 24 months were unchanged. Although tricyclic-related hepatotoxicity cannot be ruled out with a small sample, it does not appear to be a dose- or time-related phenomenon in this age group.
mesh_terms: D000293:Adolescent; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003891:Desipramine / Q000009:adverse effects* / Q000097:blood; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000503:physiopathology; D008297:Male
chemical_list: D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase; D003891:Desipramine