Hypersensitivity reaction following chloramphenicol administration in a patient with typhoid fever.
Hypersensitivity reactions due to chloramphenicol are rarely reported in the literature. We present a case report of a patient with typhoid fever who experienced a hypersensitivity reaction subsequent to the infusion of chloramphenicol sodium succinate. The patient had previously reacted similarly to ampicillin infusion. A brief review of reported cases of chloramphenicol hypersensitivity in the English-language literature, as well as possible alternative explanations in this case, are provided.
D000328:Adult; D000667:Ampicillin / Q000009:adverse effects; D002701:Chloramphenicol / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004417:Dyspnea / Q000139:chemically induced; D006801:Humans; D008297:Male; D014435:Typhoid Fever / Q000188:drug therapy*; D014581:Urticaria / Q000139:chemically induced
D002701:Chloramphenicol; D000667:Ampicillin