[Cytostatic effect of L-lysine-alpha-oxidase from Trichoderma harzianum Rifai and Trichoderma viride].
L-lysine-alpha-oxidase, a new fungal enzyme catalyzing oxidative L-lysine deamination, was shown to have an inhibitory effect on the in vitro synthesis of DNA, RNA and proteins in human carcinoma ovarian (CaOv) cells.
D000594:Amino Acid Oxidoreductases / Q000494:pharmacology*; D000970:Antineoplastic Agents; D002460:Cell Line; D004273:DNA, Neoplasm / Q000096:biosynthesis / Q000187:drug effects; D003864:Depression, Chemical; D006801:Humans; D003904:Mitosporic Fungi / Q000201:enzymology*; D009363:Neoplasm Proteins / Q000096:biosynthesis; D009369:Neoplasms / Q000378:metabolism*; D012334:RNA, Neoplasm / Q000096:biosynthesis / Q000187:drug effects; D014242:Trichoderma / Q000201:enzymology*
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D000594:Amino Acid Oxidoreductases; C041123:L-lysine oxidase
Tsitostaticheskiĭ éffekt L-lizin-alpha-oksidazy iz Trichoderma harzianum Rifai i Trichoderma viride.