[Aggregation of fibrinogen molecules in a solution].
Fibrinogen is found to be able to produce highly molecular aggregates in solution. Its maximal quantity aggregates at the temperature of 4 degrees C. The pH dependence of fibrinogen aggregates production is shown. Highly molecular aggregates of fibrinogen are found to be produced mainly due to hydrogen bonds. Electron-microphotography of aggregated fibrinogen is presented. Complementary molecular loci responsible for the formation of ordered aggregates are discussed from the standpoint of their significance in the fibrin polymerization.
D000818:Animals; D002417:Cattle; D002850:Chromatography, Gel; D005338:Fibrin Fibrinogen Degradation Products; D005340:Fibrinogen; D046911:Macromolecular Substances; D008854:Microscopy, Electron; D008970:Molecular Weight; D012996:Solutions; D013917:Thrombin
D005338:Fibrin Fibrinogen Degradation Products; D046911:Macromolecular Substances; D012996:Solutions; C011468:fibrinmonomer; D005340:Fibrinogen; D013917:Thrombin
Agregatsiia molekul fibrinogena v rastvore.