Unusual chromosome 7 aberrations in a case of eosinophilic myeloproliferative syndrome.
A patient with myeloproliferative syndrome with marked eosinophilia was found to have unusual karyotypic abnormalities, including monosomy for the short arm and part of the long arm of chromosome #7 in cultured bone marrow cells. These abnormalities have never been reported previously. The role of chromosome #7 deletions in the genesis of leukemic disorders is discussed.
D002872:Chromosome Deletion; D002897:Chromosomes, Human, Pair 7; D004802:Eosinophilia / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009006:Monosomy; D009196:Myeloproliferative Disorders / Q000235:genetics*