title: Hyperfrequency of pulmonary cancer in a population of 415 patients treated for laryngeal cancer.
abstract: Four hundred fifteen patients with laryngeal cancer were treated mainly by primary irradiation from 1965 to 1983, at the Radium Centre of Odense. By December 31, 1983, a total of 32 patients had developed pulmonary cancer. The Danish Cancer Registry calculated the expected number of pulmonary cancer in a population of the same composition from the same period of time and the same geographical locale. A statistically significant hyperfrequency of pulmonary cancer among males was found, most pronounced among supraglottic cases: 6.73. Furthermore, a cumulative estimation of the risk of developing pulmonary cancer as a function of follow-up revealed a risk of 26% during the first 14 years of follow-up. The only effective way to solve the problem is to stop smoking.
mesh_terms: D003718:Denmark; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000628:therapy*; D008175:Lung Neoplasms / Q000453:epidemiology*; D009378:Neoplasms, Multiple Primary; D012306:Risk; D012737:Sex Factors; D013997:Time Factors