title: Surgical options in the management of large omphaloceles.
abstract: Forty-six neonates with omphaloceles seen at the Children's Hospital and Medical Center in Seattle from 1975 to 1985 were reviewed. There was an 87 percent survival rate in those surgically managed. The 23 neonates who underwent primary closure all survived. The 13 neonates with giant omphaloceles with the liver in the defect who received silon chimneys had a 46 percent mortality rate and a high complication rate, with prolonged hospitalization. Two neonates with giant omphaloceles were managed by leaving the sac intact, and silver sulfadiazine cream was used as an escharotic agent. We believe it is a safer alternative than the silon chimney in neonates whose defects cannot be closed primarily.
mesh_terms: D001684:Biological Dressings; D000013:Congenital Abnormalities / Q000150:complications; D006554:Hernia, Umbilical / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D009824:Ointments; D012837:Silver Sulfadiazine / Q000627:therapeutic use; D013529:Surgical Wound Dehiscence / Q000453:epidemiology; D013530:Surgical Wound Infection / Q000453:epidemiology
chemical_list: D009824:Ointments; D012837:Silver Sulfadiazine