title: Increased aqueous lactic dehydrogenase in Coat's disease.
abstract: A case of early childhood Coats's disease in a ten-month-old boy is presented. The lactic dehydrogenase aqueous:serum ratio was very high (6:1). A ratio higher than 3:1 in Coats's disease or in any other eye infection has never been reported except in cases of retinoblastoma. Since retinoblastoma does not always show calcification in x-rays, it may be concluded that in certain cases it would be impossible to discriminate between Coats's disease and retinoblastoma (except in pathologic analysis) with any available diagnostic tools.
mesh_terms: D001082:Aqueous Humor / Q000201:enzymology*; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008297:Male; D011859:Radiography; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000000981:diagnostic imaging / Q000473:pathology; D012164:Retinal Diseases / Q000000981:diagnostic imaging / Q000201:enzymology* / Q000473:pathology
chemical_list: D007770:L-Lactate Dehydrogenase