title: [Secondary hyperparathyroidism in patients on long-term hemodialysis].
abstract: Evidence of secondary hyperparathyroidism was evaluated in 233 autopsied patients with uremia (of whom 115 patients had been treated with long-term haemodialysis). Morphology of parathyroid glands correlates with serum level of immunoreactive parathormone. Extraskeletal soft tissue calcification was observed in three different forms: 1st calcifying arteriopathy, 2nd paraarticular soft-tissue calcification and 3rd classic metastatic calcification. Hypocalcemia may lead to any of these 3 forms of tissue calcification and only local factors play a decisive role in determining which type actually occurs. Arteriopathy and paraarticular calcification of soft tissues belong to calciphylaxis and different challenger factors are presumed.
mesh_terms: D000311:Adrenal Glands / Q000473:pathology; D002114:Calcinosis / Q000209:etiology / Q000473:pathology; D002118:Calcium / Q000097:blood; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood; D006435:Renal Dialysis / Q000009:adverse effects*; D013997:Time Factors; D014511:Uremia / Q000473:pathology
chemical_list: D010281:Parathyroid Hormone; D010710:Phosphates; D002118:Calcium
vernacular_title: Sekundärer Hyperparathyreoidismus bei langfristig hämodialysierten Patienten.