A mosaic-like distribution of dopamine receptors in rat neostriatum and its relationship to striosomes.
The distribution of dopamine receptors in rat neostriatum was determined by means of light microscopic autoradiography of in vivo labeled binding sites for [3H]N-n-propylnorapomorphine and compared with the distribution of acetylcholinesterase histochemical staining. The distribution of dopamine receptors was non-homogeneous and patches of low receptor density were in register with acetylcholinesterase-poor striosomes. This suggests that the distribution pattern of dopamine receptors is specifically related to various input systems.
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001058:Apomorphine / Q000031:analogs & derivatives / Q000378:metabolism; D001345:Autoradiography; D003342:Corpus Striatum / Q000201:enzymology / Q000378:metabolism*; D006651:Histocytochemistry; D051381:Rats; D011954:Receptors, Dopamine / Q000378:metabolism*
D011954:Receptors, Dopamine; C009074:N-n-propylnorapomorphine; D000110:Acetylcholinesterase; D001058:Apomorphine