title: Semen characteristics in furazolidone-treated goats.
abstract: Furazolidone was given to male Nubian goats for 5 days at a therapeutic dose of 10 mg/kg or at a dose of 40 mg/kg, and the effect on semen morphology and biochemistry was studied. At the lower dose, furazolidone significantly reduced seminal ejaculate volume, the number of motile spermatozoa per ejaculate and the number of live spermatozoa per ejaculate, while secondary abnormalities increased. At a dose of 40 mg/kg, the same effects were produced and there were significant reductions in wave motion, percentage of motile spermatozoa and percentage of live spermatozoa. Fructose concentration was significantly reduced with both the doses, while citric acid was not affected by either one. Alkaline phosphatase activity was lower with 10 mg/kg of furazolidone and increased when the larger dose was administered.
mesh_terms: D000818:Animals; D005664:Furazolidone / Q000494:pharmacology*; D006041:Goats / Q000502:physiology*; D008297:Male; D012661:Semen / Q000032:analysis / Q000187:drug effects*; D013094:Spermatozoa / Q000187:drug effects*
chemical_list: D005664:Furazolidone