Failure of the prostaglandin F2 alpha analogue, cloprostenol, to induce functional luteolysis in the olive baboon (Papio cynocephalus anubis).
The prostaglandin F2 alpha analogue, cloprostenol, which is an effective luteolytic agent in the common marmoset, was administered intramuscularly to olive baboons to determine if it possessed luteolytic properties in this species. The results showed that functional luteolysis was not induced when cloprostenol was administered during the mid- to late luteal phase or during early pregnancy.
D000818:Animals; D003008:Cloprostenol / Q000008:administration & dosage / Q000494:pharmacology*; D004334:Drug Administration Schedule; D005260:Female; D007273:Injections, Intramuscular; D003341:Luteolysis / Q000187:drug effects*; D010215:Papio / Q000502:physiology*; D011276:Pregnanediol / Q000031:analogs & derivatives / Q000652:urine; D011374:Progesterone / Q000097:blood; D011461:Prostaglandins F, Synthetic / Q000494:pharmacology*
D011461:Prostaglandins F, Synthetic; C022270:pregnanediol-3 alpha-glucuronide; D003008:Cloprostenol; D011374:Progesterone; D011276:Pregnanediol