[Therapeutic efficacy of pantothenic acid preparations in ischemic heart disease patients].
The therapeutic effectiveness of the pantothenic acid drugs: calciipantothenas and pantethine, was studied in 182 patients with coronary heart disease and stable angina of effort. It is shown that both the drugs produce favourable effects on certain parameters of hemodynamics, on the metabolism of lipids, riboflavin and ascorbic acid. It is recommended that the administration of calciipantothenas in a dose of 300 mg/day, during 3 weeks, be included into the combined treatment of coronary patients with no manifest disorders of lipid metabolism. Patients with manifest hyperlipidemia should be administered pantethine in a dose of 500 mg/day.
D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010204:Pantetheine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use*; D010205:Pantothenic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D013438:Sulfhydryl Compounds / Q000627:therapeutic use*
D008055:Lipids; D013438:Sulfhydryl Compounds; D010205:Pantothenic Acid; D010204:Pantetheine; C005425:pantethine
Terapevticheskaia éffektivnost' preparatov pantotenovoĭ kisloty u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.