title: Ultrastructural identification and localization of climbing fiber terminals in the fastigial nucleus of the cat.
abstract: Following injections of 3H-leucine and 35S-methionine in the caudal half of the medial accessory olive, labeled climbing fibers were found contralateral to the injection site in the sagittal A-zone of the cerebellar vermis and in the fastigial nucleus. Labeling in the fastigial nucleus was analyzed with ultrastructural autoradiography. Labeled boutons of climbing fibers were found in the neuropil but never on somata. They contain spherical vesicles and occasionally some dense core vesicles in an electron-lucent matrix. The terminals of climbing fiber collaterals in the fastigial nucleus resemble climbing fiber terminals in the molecular layer with respect to their internal ultrastructural characteristics.
mesh_terms: D000344:Afferent Pathways / Q000648:ultrastructure; D000818:Animals; D001345:Autoradiography; D002415:Cats; D002529:Cerebellar Nuclei / Q000648:ultrastructure*; D009847:Olivary Nucleus / Q000648:ultrastructure*; D013569:Synapses / Q000648:ultrastructure