title: Phage-induced change of toxigenesis in Vibrio cholerae.
abstract: A temperate phage coding for constitutive hypertoxigenicity has been constructed in Vibrio cholerae strain 569B and used to lysogenise the low-toxin-producing strain MAK 757; 18% of lysogens showed 10-100-fold increase in toxin production. This property was also transmitted at low frequency to second generation lysogens. Thus temperate phage can increase toxin production in a low-toxin-producing strain.
mesh_terms: D001435:Bacteriophages / Q000502:physiology*; D002772:Cholera Toxin / Q000096:biosynthesis*; D008242:Lysogeny; D014734:Vibrio cholerae / Q000378:metabolism*
chemical_list: D002772:Cholera Toxin