Metabolism of 2-(2-thienyl)allylamine hydrochloride in the rat: identification of a novel metabolite.
A novel metabolite, 2-(2-thienyl)propionic acid, is formed in vivo from 2-(2-thienyl)allylamine hydrochloride. Mass spectral analysis suggested 2-(2-thienyl)propionic acid formation involves loss of the amine moiety followed by reduction of the olefinic group.
D000818:Animals; D002250:Carbon Radioisotopes; D002851:Chromatography, High Pressure Liquid; D008297:Male; D013058:Mass Spectrometry / Q000379:methods; D051381:Rats; D011919:Rats, Inbred Strains; D013876:Thiophenes / Q000302:isolation & purification* / Q000378:metabolism*
D002250:Carbon Radioisotopes; D013876:Thiophenes; C052698:2-(2-thienyl)propionic acid; C052697:2-(2-thienyl)allylamine