Definition of mean residence times in pharmacokinetics.
A new definition of the mean residence time is proposed which includes the commonly used definition as a special case. The advantage of the new definition is that it applies for both linear and non-linear systems. Some practical advantages which follow from the new definition are discussed. Procedures for using urinary excretion data in mean residence time estimation are discussed.
D006801:Humans; D007408:Intestinal Absorption; D007700:Kinetics; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000378:metabolism* / Q000652:urine
D004364:Pharmaceutical Preparations