Familial occurrence of typhoid acute glomerulonephritis.
Three cases of typhoid nephritis occurring in a single family are reported. A clinical similarity to poststreptococcal nephritis was noted, although no hypocomplementemia was observed. The same phage type occurred in other patients who did not exhibit nephritis. The possibility of a host factor was therefore considered to be involved, although no HLA haploid-type link was found in the patients. These cases illustrate that in certain geographical areas the possibility of typhoid fever should be considered in patients with nephritis and concomitant fever.
D000208:Acute Disease; D000293:Adolescent; D002648:Child; D005260:Female; D005921:Glomerulonephritis / Q000235:genetics*; D006801:Humans; D008297:Male; D014435:Typhoid Fever / Q000235:genetics*