title: Central and peripheral involvement in hemodialysed subjects: neurophysiological and nephrological relationships.
abstract: Nerve conduction velocity and visual evoked potential studies were conducted in 31 patients with chronic renal failure undergoing periodic hemodialysis. The results indicate damage to the central nervous system, such as delayed P100 wave, even in the absence of clinical signs, and to the peripheral nervous system, such as distal sensorimotor neuropathy. The degree of peripheral involvement correlates with the duration of dialysis and with some blood chemistry values but not with the evoked potential parameters. There is no correlation between central and peripheral nervous damage, which presumably points to a difference in pathogenesis.
mesh_terms: D000328:Adult; D000368:Aged; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D004576:Electromyography; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology*; D009431:Neural Conduction; D010281:Parathyroid Hormone / Q000097:blood; D011930:Reaction Time; D006435:Renal Dialysis
chemical_list: D010281:Parathyroid Hormone; D003404:Creatinine