Increased renal threshold of bicarbonate due to carbon dioxide retention associated with proximal renal tubular acidosis.
We report a neonate who manifested type II (proximal) renal tubular acidosis (RTA). Hypoventilation secondary to hypothalamic dysfunction led to carbon dioxide retention. The consequent changes in acid base regulation are detailed and discussed.
D000042:Absorption; D000136:Acid-Base Equilibrium; D000141:Acidosis, Renal Tubular / Q000378:metabolism*; D001639:Bicarbonates / Q000378:metabolism*; D006801:Humans; D006935:Hypercapnia / Q000378:metabolism*; D007231:Infant, Newborn; D007687:Kidney Tubules, Proximal / Q000378:metabolism*
D001639:Bicarbonates