Decreased urine production in the near-term fetal lamb after maternal ethanol infusion.
Intravenous infusion of 1 gm ethanol/kg maternal body weight over 1 hour to three conscious catheterized near-term pregnant ewes decreased fetal urine production for 3 hours (overall decrease of 54% from control). This effect in the near-term fetus is opposite to the ethanol-induced diuresis that occurs in adults.
D000818:Animals; D004231:Diuresis / Q000187:drug effects*; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005333:Fetus / Q000187:drug effects* / Q000502:physiology; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D012756:Sheep / Q000196:embryology*; D014556:Urine
D000431:Ethanol