Pemphigus.
Pemphigus is an autoimmune blistering disorder. Paradoxically intact blisters are rarely seen as the superficial blister is so fragile. The disease is frequently fatal if untreated. Pemphigus is an ideal model for autoimmunity as the antigen has been characterized and the antibody demonstrated to be pathogenic.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001323:Autoantibodies / Q000276:immunology; D001324:Autoantigens / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D003165:Complement System Proteins; D006801:Humans; D010392:Pemphigus / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D013280:Stomatitis / Q000473:pathology
D000305:Adrenal Cortex Hormones; D001323:Autoantibodies; D001324:Autoantigens; D003165:Complement System Proteins