Uptake of thyroid hormones (L-T3 and L-T4) by isolated rat adipocytes.
3,5,3'-triiodo-L-thyronine is taken up by isolated rat adipocytes under physiological conditions by a saturable sigmoidal process, while L-thyroxine uptake follows Michaelian kinetics. Comparative studies performed with intact adipocytes and derived liposomes suggest that thyroid hormones are taken up into cells via carrier-mediated transport.
D000273:Adipose Tissue / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport; D066298:In Vitro Techniques; D007700:Kinetics; D008081:Liposomes; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013974:Thyroxine / Q000378:metabolism*; D014284:Triiodothyronine / Q000378:metabolism*
D008081:Liposomes; D014284:Triiodothyronine; D013974:Thyroxine