title: Systemic efficacy of ivermectin against Dermanyssus gallinae (De Geer, 1778) in fowls.
abstract: The efficacy of ivermectin on females of a laboratory strain of Dermanyssus gallinae was tested. Ivermectin produced a noticeable systemic effect on the mites when inoculated intra-abdominally into infested chickens at rates greater than 0.6 mg kg-1. The concentrations efficacious against D. gallinae (1.8-5.4 mg kg-1) were unfavourably close to those causing toxicity in experimental birds (greater than or equal to 5.4 mg kg-1). Ivermectin administered at 5.4 mg kg-1 was active for 70 h post inoculation.
mesh_terms: D000818:Animals; D001835:Body Weight; D002645:Chickens; D005260:Female; D007559:Ivermectin / Q000627:therapeutic use* / Q000633:toxicity; D008924:Mite Infestations / Q000188:drug therapy / Q000662:veterinary*; D008925:Mites / Q000187:drug effects; D011201:Poultry Diseases / Q000188:drug therapy*
chemical_list: D007559:Ivermectin