[Ultrastructure of subendocardial Purkinje cells and left-ventricular pseudotendons in sudden coronary death].
Ultrastructure of subendocardial Purkinje cells and left ventricular false tendons was studied in 13 cases of sudden coronary death (SCD). In some observations different degrees of the conducting bundle cells atrophy up to their complete disappearance were found in the false tendons while in death of craniocerebral injury (control) partial atrophy of Purkinje cells was a rare finding. Evaluation of changes in the conducting cell ultrastructure in SCD has shown the presence of sarcoplasmic reticulum vacuolization, divergence of membranes in intercalated disks, myofibrillar overcontraction. All these changes observed both in false tendons and in the subendocardium were always present in various combinations in all 13 cases of SCD and may contribute to the onset of cardiac arrhythmias, lethal outcome.
D000328:Adult; D000368:Aged; D001284:Atrophy; D003327:Coronary Disease / Q000473:pathology*; D003645:Death, Sudden / Q000473:pathology*; D006329:Heart Conduction System / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D009940:Organoids / Q000648:ultrastructure; D011690:Purkinje Fibers / Q000648:ultrastructure*
Ul'trastruktura kletok Purkin'e subéndokarda i lozhnykh sukhozhiliĭ levogo zheludochka serdtsa pri vnezapnoĭ koronarnoĭ smerti.