title: Preparation and maintenance of rats with chronic esophagostomy and gastric cannula.
abstract: We describe surgical and maintenance procedures for the "double-fistula" preparation in rat. Rats are prepared with esophageal fistulas, so that material swallowed escapes from an opening in the throat; and with gastric cannulas that permit both nutritional and hydrational maintenance, and the experimental intubation of fluids directly into the stomach.
mesh_terms: D000818:Animals; D002404:Catheterization; D005402:Fistula; D051381:Rats; D013270:Stomach / Q000601:surgery*; D013997:Time Factors