Development of a method to monitor low molecular mass hydrocarbons in exhaled breath of man: preliminary evaluation of its interest for detecting a lipoperoxidation process in vivo.
Low molecular mass hydrocarbons, particularly ethane and pentane, have been measured in expired air of man. The air is collected into 5-10 l polyamide bags. After removal of water vapour and CO2, the hydrocarbons are concentrated on a silicagel column kept at 0 degree C. The column desorption is carried out at 290 degrees C, and the gases are analysed by gas chromatography. A slight but statistically significant increased pentane production was detected in cirrhotic patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001944:Breath Tests / Q000379:methods*; D002849:Chromatography, Gas / Q000379:methods; D004980:Ethane / Q000032:analysis; D005260:Female; D006801:Humans; D006838:Hydrocarbons / Q000032:analysis*; D008054:Lipid Peroxides / Q000378:metabolism*; D008107:Liver Diseases / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D010420:Pentanes / Q000032:analysis
D006838:Hydrocarbons; D008054:Lipid Peroxides; D010420:Pentanes; C033353:pentane; D004980:Ethane