Mycobacterium marinum infections of the hand.
Fifteen patients had culture proven Mycobacterium marinum infections of the hand; 11 had injured their hands while fishing in water around Long Island. No patient had type I lesions (verrucal), six patients had type II lesions (subcutaneous granulomas), and nine patients had type III lesions (deep). Histologic examination showed noncaseating granulomas in all cases. A specific defect in the patients' lymphocytes ability to respond to M. marinum antigens was identified. A combination of surgery and tetracycline provided effective treatment. Follow-up averaged 2 1/2 years.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006225:Hand / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009164:Mycobacterium Infections / Q000628:therapy*; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000276:immunology / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D011446:Prospective Studies; D012189:Retrospective Studies; D012882:Skin Tests
D000900:Anti-Bacterial Agents