title: Dapsone as initial treatment in superficial pemphigus. Report of nine cases.
abstract: Nine cases of superficial pemphigus that were treated by dapsone as the initial mode of therapy are reported. Five patients, all having low or negative serum anti-intercellular cement substance antibody titers, responded dramatically, while the other four patients, showing high titers of anti-intercellular cement substance antibodies, did not respond to this treatment. Complications of therapy were observed in three cases.
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001323:Autoantibodies / Q000032:analysis; D003520:Cyclophosphamide / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use*; D004351:Drug Resistance; D005110:Extracellular Space / Q000276:immunology; D006801:Humans; D008875:Middle Aged; D010392:Pemphigus / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D001323:Autoantibodies; D003520:Cyclophosphamide; D003622:Dapsone; D011239:Prednisolone