The relative biological effectiveness of 100 kV X-rays determined by the V-79 cell colony assay.
The relative biological effectiveness (RBE) of 100 kV X-rays compared with cobalt-60-gamma-irradiation was determined using a cell colony assay based on the survival of Chinese hamster V-79 lung fibroblasts. The 37% dose (Do) was found to range from 1.12 to 1.47 and from 1.33 to 1.63 Gy for X-rays and 60Co-gamma-irradiation respectively. The mean RBE value calculated from the Do values was found to be 1.13 +/- 0.04. This figure compares favourably with RBE values calculated from Do values using other endpoints.
D000818:Animals; D002478:Cells, Cultured / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D003114:Colony-Forming Units Assay; D006224:Cricetinae; D005347:Fibroblasts / Q000528:radiation effects; D011879:Radiotherapy Dosage; D014965:X-Rays
D003037:Cobalt Radioisotopes