[Effect of B-activin on the rosette-forming capacity of mouse lymphocytes at the peak of a secondary immune response to ram erythrocytes].
The effect of B-activin secreted by bone-marrow cells in response to the expression of antigen-recognizing receptors at the peak of immune response to SRBC was studied. A negative correlation between the number of immune RFC and antibody-producing cells under the influence of B-activin was established. It was shown that the decrease in the number of immune RFC was the result of precommitted B-lymphocyte maturation into plasmatic cells.
D028341:Activins; D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology; D002478:Cells, Cultured; D004912:Erythrocytes / Q000276:immunology*; D007117:Immunization, Secondary; D008198:Lymph Nodes / Q000187:drug effects / Q000276:immunology; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009842:Oligopeptides; D010455:Peptides / Q000494:pharmacology*; D012397:Rosette Formation; D013154:Spleen / Q000187:drug effects / Q000276:immunology
D000276:Adjuvants, Immunologic; D009842:Oligopeptides; D010455:Peptides; C044147:activin B; D028341:Activins; C048617:myelopeptides
Vliianie B-aktivna na rozetkoobrazuiushchuiu sposobnost' limfotsitov mysheĭ na pike vtorichnogo immunnogo otveta na éritrotsity barana.