Nontraumatic subdural hematoma in a patient with osteogenesis imperfecta and renal failure.
Intracranial hematomas in patients with osteogenesis imperfecta rarely are reported despite an increased incidence of skull fractures. We present a case of a patient with osteogenesis imperfecta but without any history of trauma or chronic anticoagulation in whom a subdural hematoma occurred during hemodialysis. Despite operative intervention, the patient died. We could find no other cases in the medical literature of a patient with osteogenesis imperfecta who had an intracranial hematoma in the absence of a skull fracture. Patients with osteogenesis imperfecta may be at high risk for intracranial bleeding from coagulation abnormalities or otherwise trivial injuries.
D000328:Adult; D006408:Hematoma, Subdural / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications*; D006435:Renal Dialysis / Q000009:adverse effects