[Changes in brain energy metabolism in experimental cerebral hemorrhage].
Intracerebral hemorrhage impaired the functional activity of rat brain mitochondria. After experimental insult the rate of succinate and alpha-ketoglutarate oxidation was decreased at the states 3 and 4 in brain mitochondria as well as in presence of 2,4-dinitrophenol. The rate of phosphorylation was also decreased in oxidation of both NAD- and FAD-dependent substrates.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002543:Cerebral Hemorrhage / Q000378:metabolism*; D004734:Energy Metabolism; D008297:Male; D008928:Mitochondria / Q000378:metabolism; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D051381:Rats
Narushenie énergeticheskogo metabolizma mozga pri éksperimental'nom vnutrimozgovom krovoizliianii.