Cholinergic projections in the telencephalo-habenulo-interpeduncular system of the goldfish.
Experiments were performed in order to see whether acetylcholine is a neurotransmitter in the telencephalo-habenulo-interpeduncular system of the goldfish. After telencephalic ablation choline acetyltransferase decreased by 53% in the habenular nuclei but was unchanged in the interpeduncular nucleus. After combined telencephalic and habenular lesions, the enzyme level dropped by 95% in the interpeduncular nucleus. These results suggest the existence of a telencephalo-habenular and a habenulo-interpeduncular cholinergic projection in the goldfish, as previously demonstrated in mammals. Acetylcholinesterase histochemistry additionally demonstrates some similarities between the habenulae and the interpeduncular nucleus in the goldfish and in mammals.
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D002799:Cholinergic Fibers / Q000033:anatomy & histology* / Q000201:enzymology; D003530:Cyprinidae / Q000033:anatomy & histology*; D004027:Diencephalon / Q000033:anatomy & histology* / Q000201:enzymology; D006054:Goldfish / Q000033:anatomy & histology* / Q000378:metabolism; D006651:Histocytochemistry; D008854:Microscopy, Electron; D009434:Neural Pathways / Q000033:anatomy & histology; D013681:Tegmentum Mesencephali / Q000033:anatomy & histology* / Q000201:enzymology; D013687:Telencephalon / Q000033:anatomy & histology / Q000502:physiology
D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase