title: Trial of nifedipine for prevention of oesophageal spasm.
abstract: We have used a placebo controlled trial to investigate the effect of long-term administration of nifedipine in the prevention of symptomatic episodes of oesophageal spasm. Diary card scoring was used to assess symptoms in 8 patients with oesophageal spasm who were each given nifedipine and placebo for at least 6 weeks. No significant differences in symptoms between the nifedipine and placebo treatment periods were seen.
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D004341:Drug Evaluation; D004935:Esophageal Diseases / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D013035:Spasm / Q000517:prevention & control
chemical_list: D009543:Nifedipine