Acetylation and hydroxylation of sulphatroxazole in the snail Cepaea hortensis and the slug Arion rufus.
The snail Cepaea hortensis can acetylate and hydroxylate sulphatroxazole via a pathway similar to that in man. The principal metabolic pathways, in order of decreasing rate, are hydroxylation, glucuronidation and acetylation. The slug Arion rufus also can acetylate and hydroxylate sulphatroxazole, although, in contrast to the snail, is rate of acetylation is higher than that of hydroxylation.
D000107:Acetylation; D000818:Animals; D006900:Hydroxylation; D007700:Kinetics; D008974:Mollusca / Q000378:metabolism*; D012908:Snails / Q000378:metabolism*; D013420:Sulfamethoxazole / Q000031:analogs & derivatives* / Q000378:metabolism
D013420:Sulfamethoxazole; C048358:sulfatroxazole