CHARGE association in neonates presenting with choanal atresia.
Ten infants presented with choanal atresia. Four showed 4 or more components of CHARGE association, 3 of whom died before the age of 2 months while infants with choanal atresia but not having other features of CHARGE association survived. The combination of choanal atresia and heart disease carries a very high risk.
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D002754:Choanal Atresia / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D013577:Syndrome