title: [Brain neurite-stimulating protein].
abstract: A protein possessing the neurite-stimulating activity in organotypic cultures of chicken embryo spinal ganglia was isolated and purified from bovine brain tissue. The isolation and purification procedures included acid extraction, ultrafiltration, preparative polyacrylamide gel electrophoresis and chromatography on heparin-Sepharose. The molecular weight of the protein is about 15000 Da. The neurite-stimulating activity of the purified protein manifests itself at a protein concentration of about 10(-9) M.
mesh_terms: D000818:Animals; D001369:Axons / Q000166:cytology*; D001923:Brain Chemistry; D002417:Cattle; D002642:Chick Embryo; D009414:Nerve Growth Factors; D009924:Organ Culture Techniques; D010455:Peptides / Q000302:isolation & purification* / Q000502:physiology
chemical_list: D009414:Nerve Growth Factors; D010455:Peptides; C047805:neurite-inducing factor
vernacular_title: Mozgovoĭ neĭritstimuliruiushchiĭ belok.