Cold sensitivity after replantation in relation to arterial circulation and vasoregulation.
Cold intolerance is a common problem after injuries to the hand. To elucidate the mechanism of this cold sensitivity, eight patients with successful replantations of amputations of the thumb or index finger were studied one and half years later. In six patients the Doppler signal from the anastomosed arteries was normal and in two patients signs of mild stenosis were found. All patients had normal or slightly reduced basal finger systolic pressure in the replanted finger. Six had signs of marked vasospasm. Alpha-receptor blockade had no effect on the cold-induced decrease in finger systolic pressure in the replanted finger. It is concluded that cold intolerance after hand injuries results from a defect in vasoregulation and is not caused by organic insufficiency of the circulation.
D000328:Adult; D000673:Amputation, Traumatic / Q000601:surgery*; D003080:Cold Temperature; D005260:Female; D005383:Finger Injuries / Q000601:surgery*; D005385:Fingers / Q000098:blood supply / Q000601:surgery; D006801:Humans; D008297:Male; D012092:Replantation; D013933:Thumb / Q000098:blood supply / Q000601:surgery*