title: [Skeletal and velar myoclonus with vision disorders. Efficacy of carbamazepine].
abstract: The authors report the case of a 71 year-old woman presenting right velopharyngo-laryngeal and skeletal rhythmic myoclonus, associated with visual and phasic disorders. They appeared four months after an infarct in the region of the left posterior cerebral artery. The ischemia was of temporo-occipital location, very probably extending to the region of the left red nucleus, thereby interrupting the dento-olivary pathway. Several drugs which are usually active in the treatment of myoclonus proved ineffective. But carbamazepine at a dose of 600 mg per day was effective from the third day and remained so after seven months. It would seem to act by inhibiting the occurrence of paroxystic discharges of an epileptic type in the olivary body disinhibited by the underlying lesion.
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology; D002220:Carbamazepine / Q000627:therapeutic use*; D002544:Cerebral Infarction / Q000150:complications; D005260:Female; D006801:Humans; D009207:Myoclonus / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D010160:Palate, Soft; D014786:Vision Disorders / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology
chemical_list: D002220:Carbamazepine
vernacular_title: Myoclonies squelettiques et du voile avec troubles visuels. Efficacité de la carbamazépine.