[Combined pizotiphen and cinnarizine treatment in urticaria factitia].
30 patients suffering from urticaria factitia were treated with pizotiphen and cinnarizin for 6 weeks. In 13 patients, the effect of treatment was controlled by means of the dermographism test. Placebo administration failed to affect the subjective and objective symptoms. During treatment with pizotiphen and cinnarizin, the flare significantly decreased within the first week and finally did not differ from that observed in healthy persons after 6 weeks of therapy. 19 out of 30 patients were totally free of symptoms. In 11 cases, treatment resulted in significant reduction of the urticaria, but only 7 patients still complained of itching. After repetition of the therapy, 5 patients were free of symptoms; 2 patients still reported on slight itching one year after treatment.
D000328:Adult; D002936:Cinnarizine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D010918:Pizotyline / Q000627:therapeutic use*; D013876:Thiophenes / Q000627:therapeutic use*; D014581:Urticaria / Q000188:drug therapy*
D013876:Thiophenes; D010918:Pizotyline; D002936:Cinnarizine
Kombinierte Pizotiphen- und Cinnarizinbehandlung (PCB) bei der Urticaria factitia.