title: A remarkable response of chronic severe obsessive-compulsive neurosis to phenelzine.
abstract: The author describes a 22-year-old male who suffered from chronic severe Obsessive-Compulsive Neurosis (OCN) complicated by frequent depressive episodes. Administering the monoamine oxidase inhibitor phenelzine in high dosage led to complete alleviation of his depression in 10 weeks, and 3 weeks afterwards the OCN was markedly improved. The illness relapsed shortly after discontinuance of the drug.
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000523:psychology; D010624:Phenelzine / Q000627:therapeutic use*
chemical_list: D010624:Phenelzine