Conformation of colicin A: apparent difference between cytoplasmic and extracellular polypeptide chain.
Cytoplasmic colicin A has the ability to bind to membranes and to form stable dimers. This form remains stable even in the presence of 1% SDS at 25 degrees C. Both of these properties were not observed for extracellular colicin A suggesting a possible difference in the conformation between cytoplasmic and extracellular colicin A.
D002462:Cell Membrane / Q000378:metabolism; D003087:Colicins / Q000378:metabolism; D003593:Cytoplasm; D005110:Extracellular Space; D046911:Macromolecular Substances; D008970:Molecular Weight; D011485:Protein Binding; D011487:Protein Conformation; D011499:Protein Processing, Post-Translational; D013329:Structure-Activity Relationship
D003087:Colicins; D046911:Macromolecular Substances