title: Intrahepatic cholestasis of pregnancy with marked elevation of transaminases in a black American.
abstract: A case of intrahepatic cholestasis of pregnancy (ICP) in a black American is presented. This is the first case reported in a black. Marked elevation of transaminases with mild biochemical evidence of cholestasis was initially suggestive of viral hepatitis. A clinical course characterized by pruritus with minimal constitutional symptoms, rapid resolution of biochemical abnormalities after delivery, and negative hepatitis A and B serologies was consistent with the diagnosis of ICP. Review of the classic features of ICP with emphasis on some unusual aspects of the disorder is included.
mesh_terms: D000328:Adult; D044383:Black People; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis / Q000201:enzymology* / Q000235:genetics; D003937:Diagnosis, Differential; D005260:Female; D006505:Hepatitis / Q000175:diagnosis; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000201:enzymology* / Q000235:genetics; D000637:Transaminases / Q000097:blood*; D001741:Black or African American
chemical_list: D000637:Transaminases