A comparison of some gradient-encoded volume-selection techniques for in vivo NMR spectroscopy.
Four of the techniques proposed for in vivo volume-selected NMR spectroscopy have been compared using a simple phantom with a large background water signal which was outside the region of interest. The methods VSE, SPACE, SPARS, and DIGGER all use pulsed field gradients for spatial encoding and were tested with a symmetric and an asymmetric phantom. SPACE was used to obtain volume-selected 1H NMR spectra of a human leg, demonstrating excellent discrimination between bone marrow and muscle.
D006801:Humans; D007866:Leg / Q000033:anatomy & histology; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008961:Models, Structural