[Platelet glycoprotein complex IIb-IIIa: a polyvalent membrane receptor?].
A complex formed from two membrane glycoproteins, GP IIb-IIIa, is associated with several functional activities of the platelet membrane: as a binding site for various adhesive proteins involved in adhesion and aggregation of platelets; and as a putative receptor for the Fc portion of IgE. The possibility of multiple functional domains being present within this complex is considered.
D001792:Blood Platelets / Q000378:metabolism; D005340:Fibrinogen / Q000378:metabolism; D006023:Glycoproteins / Q000172:deficiency / Q000502:physiology*; D008562:Membrane Glycoproteins; D010974:Platelet Aggregation; D010980:Platelet Membrane Glycoproteins / Q000172:deficiency / Q000502:physiology*; D013915:Thrombasthenia / Q000503:physiopathology
D006023:Glycoproteins; D008562:Membrane Glycoproteins; D010980:Platelet Membrane Glycoproteins; C040580:glycoprotein GP III; D005340:Fibrinogen
Complexe glycoprotéique plaquettaire IIb-IIIa: un récepteur membranaire plurivalent?