title: Unit activity in the nucleus triangularis septi of the rat following blood pressure changes or vasoactive peptides, and electrically stimulated blood pressure decreases.
abstract: The nucleus Triangularis Septi (TS) of anesthetized rats was studied using iontophoretic application of various vasoactive peptides (vasopressin and angiotensin) to a small number of the cells in this nucleus and blood pressure recordings during electrical stimulation of the nucleus. In the iontophoretic study 83% of the cells investigated were found to be sensitive to iontophoretic application or intracerebroventricular infusion of angiotensin II and vasopressin and that 40% of these cells were sensitive to spontaneous or induced increases of blood pressure. Electrical stimulation of the nucleus produced a reliable and reproducible decrease in blood pressure without any change in heart rate. Therefore the possible role of the TS in blood pressure regulation is discussed.
mesh_terms: D000804:Angiotensin II / Q000494:pharmacology; D000818:Animals; D001794:Blood Pressure; D004558:Electric Stimulation; D004594:Electrophysiology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012686:Septal Nuclei / Q000187:drug effects / Q000502:physiology*; D013356:Subfornical Organ / Q000502:physiology; D014667:Vasopressins / Q000494:pharmacology; D014882:Water-Electrolyte Balance
chemical_list: D014667:Vasopressins; D000804:Angiotensin II