Desmosine and isodesmosine as cross-links in the hinge-ligament protein of bivalves. 3,3'-Methylenebistyrosine as an artefact.
Desmosine and isodesmosine were detected in an invertebrate molluscan species, i.e. in an insoluble protein in the hinge ligament of a bivalve species, Sakhalin surf clam (Pseudocardium sachalinensis, in family Mactridae). The protein is rich in glycine and methionine S-oxide but devoid of hydroxyproline and hydroxylysine. 3,3'-Methylenebistyrosine was also detected in the HCl hydrolysate of the hinge-ligament protein, but it was found to be an artefact produced from tyrosine and formaldehyde derived from methionine S-oxide during the HCl hydrolysis of the protein.
D000596:Amino Acids / Q000302:isolation & purification*; D000818:Animals; D049872:Bivalvia / Q000032:analysis*; D003432:Cross-Linking Reagents; D003895:Desmosine / Q000302:isolation & purification*; D007524:Isodesmosine / Q000302:isolation & purification*; D008022:Ligaments / Q000032:analysis*; D011487:Protein Conformation; D011506:Proteins / Q000032:analysis; D014443:Tyrosine / Q000031:analogs & derivatives / Q000302:isolation & purification
D000596:Amino Acids; D003432:Cross-Linking Reagents; D011506:Proteins; D003895:Desmosine; C052274:3,3'-methylenebis(tyrosine); D014443:Tyrosine; D007524:Isodesmosine