Immunological studies of uveitis. 2. Immune complex containing retinal S antigen in patient with chronic intractable uveitis.
A case of chronic uveitis resistant to steroid treatment was reported where plasma exchange therapy, in contrast, had a remarkable effect on reducing the cystoid macular edema and retinal phlebitis. The removed plasma showed an elevated level of immune complex, and Western blotting demonstrated that this immune complex in the plasma contained retinal S antigen.
D000328:Adult; D000936:Antigen-Antibody Complex / Q000276:immunology*; D000941:Antigens / Q000032:analysis*; D019393:Arrestin; D002908:Chronic Disease; D003078:Colchicine / Q000627:therapeutic use; D004351:Drug Resistance; D005136:Eye Proteins / Q000032:analysis*; D005451:Fluorescein Angiography; D006801:Humans; D008269:Macular Edema / Q000188:drug therapy / Q000473:pathology; D008297:Male; D010689:Phlebitis / Q000188:drug therapy / Q000473:pathology; D012171:Retinal Vessels; D014605:Uveitis / Q000276:immunology*
D000936:Antigen-Antibody Complex; D000941:Antigens; D019393:Arrestin; D005136:Eye Proteins; D003078:Colchicine