title: Tissue penetration and metabolism of ciprofloxacin.
abstract: The tissue penetration of ciprofloxacin was studied by two methods. Penetration into inflammatory fluid following oral administration (500 mg) was 117 percent; following intravenous administration (100 mg), penetration was 121 percent. The penetration of ciprofloxacin into uninflamed peritoneum following intravenous administration (100 mg) was 95 percent.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D001682:Biological Availability; D001768:Blister / Q000378:metabolism; D001826:Body Fluids / Q000378:metabolism; D002939:Ciprofloxacin / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D007275:Injections, Intravenous; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010529:Peritoneal Cavity / Q000378:metabolism
chemical_list: D002939:Ciprofloxacin