Elevated cerebrospinal fluid vasopressin in motor neuron disease.
CSF vasopressin levels were significantly elevated in eight patients with motor neuron disease (2.5 +/- 0.4 pmol/l) compared with controls (0.7 +/- 0.1 pmol/l). CSF oxytocin and plasma vasopressin concentrations were similar in the two groups. This finding may be a primary part of the disease process or an epiphenomenon related to increased autonomic and descending pathway activity secondary to abnormal function and/or loss of anterior horn cells.
D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009468:Neuromuscular Diseases / Q000097:blood / Q000134:cerebrospinal fluid*; D010121:Oxytocin / Q000097:blood / Q000134:cerebrospinal fluid; D014667:Vasopressins / Q000097:blood / Q000134:cerebrospinal fluid*
D014667:Vasopressins; D010121:Oxytocin