Severe hypertension, propranolol, and acute pulmonary edema.
We describe an elderly patient with multiple risk factors for congestive heart failure (CHF) who developed severe hypertension. Treatment with 20 mg hydralazine and 0.2 mg propranolol intravenously resulted in acute pulmonary edema. We conclude that beta-blocking agents may precipitate acute heart failure in patients with compensated CHF.
D000368:Aged; D000369:Aged, 80 and over; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000150:complications; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D011433:Propranolol / Q000009:adverse effects* / Q000627:therapeutic use; D011654:Pulmonary Edema / Q000139:chemically induced*; D012306:Risk
D006830:Hydralazine; D011433:Propranolol