[Lipid peroxidation and free Fe2+ during ischemia and reoxygenation of the liver].
Ischemia and reoxygenation were experimentally induced in thin liver sections. It has been shown that free iron decompartmentalization takes place 30 min after the induction of ischemia, with no lipid peroxidation activation observed. In reoxygenation, activation of lipid peroxidation and decrease in free iron concentration take place in the liver cells. It is suggested that free iron accumulation in the tissues during ischemia causes lipid peroxidation activation during reoxygenation.
D000818:Animals; D066298:In Vitro Techniques; D007501:Iron / Q000378:metabolism*; D007511:Ischemia / Q000378:metabolism*; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008099:Liver / Q000098:blood supply* / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism*; D051381:Rats
D008054:Lipid Peroxides; D007501:Iron; D010100:Oxygen
Perekisnoe okislenie lipidov i svobodnoe Fe2+ pri ishemii i reoksigenatsii pecheni.