title: [Synthesis and antimicrobial activity of 3-nitroisoxazole derivatives].
abstract: Some azomethine type compounds from 3-nitroisoxazole-5-carboxy-aldehyde were synthesized; among these the most active, oxime (III a), shows bacteriostatic activity in vitro against gram--comparable to that of nitrofurantoin.
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D055598:Chemical Phenomena; D002621:Chemistry; D007555:Isoxazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009574:Nitro Compounds / Q000138:chemical synthesis / Q000494:pharmacology; D010080:Oxazoles / Q000138:chemical synthesis*
chemical_list: D000900:Anti-Bacterial Agents; D007555:Isoxazoles; D009574:Nitro Compounds; D010080:Oxazoles
vernacular_title: Sintesi ed attività' antimicrobica in vitro di derivati 3-nitroisossazolici.