Acquired coagulation inhibitor in association with Rocky Mountain spotted fever. With a review of other acquired coagulation inhibitors.
An acutely ill 4-year-old girl with Rocky Mountain spotted fever (RMSF) was found to have a coagulation inhibitor. This child had no serious bleeding manifestations and minimal hemorrhagic skin manifestations despite severe RMSF, concurrent thrombocytopenia, as well as the coagulation inhibitor. Hemostatic abnormalities that occur with RMSF as well as other infectious illnesses associated with coagulation inhibitors are reviewed.
D001323:Autoantibodies / Q000032:analysis; D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000209:etiology*; D001779:Blood Coagulation Factors / Q000037:antagonists & inhibitors*; D001780:Blood Coagulation Tests; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000276:immunology; D010314:Partial Thromboplastin Time; D012373:Rocky Mountain Spotted Fever / Q000097:blood* / Q000150:complications; D013925:Thromboplastin / Q000037:antagonists & inhibitors
D001323:Autoantibodies; D001779:Blood Coagulation Factors; D013925:Thromboplastin