title: Immunocytochemical localization of protein kinase C in resting and activated human neutrophils.
abstract: An immunocytochemical method was used to determine possible changes in the subcellular distribution of protein kinase C (PKC) in human neutrophils in response to opsonized latex beads and zymosan. While in resting cells most of the PKC immunoreactivity was localized in the cytoplasm, a redistribution of PKC to the plasma and phagosomal membranes was observed in cells treated with latex beads or zymosan for 5-20 min, suggesting a participation of PKC in endocytosis.
mesh_terms: D000328:Adult; D002462:Cell Membrane / Q000201:enzymology; D003593:Cytoplasm / Q000201:enzymology; D006651:Histocytochemistry; D006801:Humans; D009504:Neutrophils / Q000201:enzymology*; D010587:Phagocytosis; D011493:Protein Kinase C / Q000097:blood* / Q000276:immunology; D015054:Zymosan / Q000494:pharmacology
chemical_list: D015054:Zymosan; D011493:Protein Kinase C