[Effects of a single intra-articular injection of antibiotics on cartilage structure in rabbits].
Nebacetin, chloramphenicol, penicillin, and isotonic sodium chloride solution were injected once into 80 knee- and elbow-joints of rabbits. The histologic investigation of the hyaline cartilage after 2 respectively 5 months did not show any kind of lesions. The results of other authors in similar investigations and the indication for intra-articular application of antibiotics are discussed.
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D001414:Bacitracin / Q000494:pharmacology; D002358:Cartilage, Articular / Q000166:cytology* / Q000187:drug effects; D002701:Chloramphenicol / Q000008:administration & dosage / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D009355:Neomycin / Q000494:pharmacology; D010406:Penicillins / Q000008:administration & dosage / Q000494:pharmacology*; D011817:Rabbits
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004338:Drug Combinations; D010406:Penicillins; D001414:Bacitracin; D002701:Chloramphenicol; C003903:Nebacetin; D009355:Neomycin
Auswirkungen einmaliger intraartikulärer Antibiotikagaben auf die Knorpelstruktur beim Kaninchen.