A controlled clinical study on the efficacy of benzydamine in the topical treatment of non-specific cervicitis and vaginitis.
The authors report the results achieved in a controlled clinical study carried out for evaluating the efficacy of some topical preparations in the treatment of the so-called non-specific cervicovaginitis. The best results have been observed in 55 patients treated with a 0.1% benzydamine solution, whose efficacy was found to be significantly greater than that of povidone-iodine vaginal suppositories or a 0.2% aluminium acetate solution that were used in an additional 45 patients suffering from non-specific vulvovaginitis and exocervicitis, according to a fully randomized experimental study protocol. The results obtained in the non-selected population of the present study confirm the usefulness of benzydamine vaginal douches in the therapy of non-specific inflammations involving the lower female genital apparatus.
D000085:Acetates / Q000008:administration & dosage; D000282:Administration, Intravaginal; D000328:Adult; D001591:Benzydamine / Q000008:administration & dosage*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D010570:Pessaries; D011206:Povidone-Iodine / Q000008:administration & dosage; D011720:Pyrazoles / Q000008:administration & dosage*; D011897:Random Allocation; D007507:Therapeutic Irrigation; D002575:Uterine Cervicitis / Q000188:drug therapy*; D014627:Vaginitis / Q000188:drug therapy*
D000085:Acetates; D011720:Pyrazoles; D001591:Benzydamine; C013396:aluminum acetate; D011206:Povidone-Iodine