Contact allergy to 4-isopropyl-dibenzoylmethane and 3-(4'-methylbenzylidene) camphor in the sunscreen Eusolex 8021.
10 cases of contact allergy from the sunscreen Eusolex 8021 are reported. 5 patients were sensitized to a lipstick, 4 to a sunscreen cream, and 1 reacted to several cosmetic creams. Of 9 patients tested with the 2 ingredients of Eusolex 8021, 5 proved to be allergic to both (chemically unrelated) constituents: 4-isopropyl-dibenzoylmethane and 3-(4'-methylbenzylidene) camphor; 4 were allergic to 4-isopropyl-dibenzoylmethane only. Contact allergy to this recently introduced broad spectrum sunscreen may not be rare. The relevant literature is reviewed.
D000328:Adult; D001565:Benzoates / Q000009:adverse effects*; D002164:Camphor / Q000009:adverse effects* / Q000031:analogs & derivatives*; D047188:Chalcones; D003429:Cross Reactions; D003877:Dermatitis, Contact / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012882:Skin Tests; D013473:Sunscreening Agents / Q000009:adverse effects*
D001565:Benzoates; D047188:Chalcones; D013473:Sunscreening Agents; C049936:4-isopropyldibenzoylmethane; D002164:Camphor; C038939:enzacamene