title: [School screening of hemoglobinopathies in the Marseilles area. An analytic study of 35,289 tests].
abstract: A systematic screening for thalassemias and hemoglobinopathies was performed in 35,289 children with a double test associating blood cell counts and hemoglobin electrophoresis. Four hundred thirty-seven (1.23%) hemoglobin abnormalities were found, consisting of 274 cases with thalassemia (0.77%) and 159 hemoglobinopathies (0.45%) among which there were 80 cases with sickle-cell trait (0.22%), 30 with hemoglobin C (Hb C) (0.08%), 19 with Hb D (0.05%), 12 with HbJ (0.03%), 12 with Hb E (0.03%). There was an obvious ethnic influence as, among 17,180 autochtonal French children, only 15 abnormalities were found (0.08%) while 392 were found in 16,850 non autochtonal children (2.32%) and 30 in 1,259 French children from Corsica (2.38%). The highest incidence was found in Italians (173 of 6,455-2.68%) and Maugrabins (105 of 3,014-3.48%).
mesh_terms: D000293:Adolescent; D005006:Ethnicity; D005260:Female; D005602:France; D006453:Hemoglobinopathies / Q000453:epidemiology*; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D012572:School Health Services; D014171:Transients and Migrants
chemical_list: D006454:Hemoglobins
vernacular_title: Dépistage scolaire des hémoglobinoses dans la région marseillaise. Etude analytique de 35,289 examens.