A randomized control study of oxytocin augmentation of labour. 1. Obstetric outcome.
Sixty women who were progressing slowly in spontaneous labour were assigned at random to three management protocols. Group 1 were observed without the use of oxytocin for 8 h while groups 2 and 3 were managed with a low-dose and high-dose oxytocin protocol respectively. The caesarean section rates were not significantly different between the three groups: 45%, 35% and 26% respectively. Cervical dilatation rate increased significantly after oxytocin infusion in both treatment groups compared with controls. The 'delay-to-delivery' interval and second stage duration were significantly shorter in the high-dose group than in the control group. There were no measurable differences in the condition of the newborn infants between the three groups.
D002584:Cervix Uteri / Q000187:drug effects; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced; D007743:Labor, Obstetric / Q000502:physiology*; D010121:Oxytocin / Q000008:administration & dosage*; D010342:Patient Acceptance of Health Care; D010865:Pilot Projects; D011247:Pregnancy; D011379:Prognosis; D011897:Random Allocation
D010121:Oxytocin