title: The renal lesions of tuberous sclerosis.
abstract: Renal involvement in the tuberous sclerosis complex includes angiomyolipomas, cysts, and carcinomas. Angiomyolipomas, despite a sometimes frightening histopathologic appearance, are benign. Cystic disease, apparently resulting from tubular epithelial hyperplasia, causes hypertension and renal insufficiency, progressing to end-stage renal disease. The same epithelial hyperplasia predisposes to renal carcinoma.
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006391:Hemangioma / Q000150:complications / Q000473:pathology; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000150:complications / Q000473:pathology*; D007680:Kidney Neoplasms / Q000209:etiology / Q000473:pathology*; D008067:Lipoma / Q000150:complications / Q000473:pathology; D008297:Male; D014402:Tuberous Sclerosis / Q000150:complications*