Comparison of monoclonal antisera with conventional antisera for Lewis blood group antigen determination.
Monoclonal blood grouping sera provide a means of overcoming difficulties inherent in the use of conventional polyclonal reagents. Two murine monoclonal anti-Lewis reagents were tested and found to be comparable to conventional reagents for use in red cell phenotyping. These reagents may detect Le(a) antigen on Le(a-b+) red cells with greater sensitivity than previously available polyclonal anti-Lewis reagents.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D001788:Blood Grouping and Crossmatching; D006801:Humans; D007518:Isoantibodies / Q000276:immunology*; D007983:Lewis Blood Group Antigens / Q000235:genetics / Q000276:immunology*; D010641:Phenotype
D000911:Antibodies, Monoclonal; D007518:Isoantibodies; D007983:Lewis Blood Group Antigens