CSF-adrenaline--low in "somatizing depression".
Cerebrospinal fluid (CSF) adrenaline and noradrenaline were measured in 14 depressed patients and in seven controls. CSF-adrenaline, but not noradrenaline, was significantly reduced in the depressed patients. Moreover, a significantly negative correlation between "anxiety, somatic", "hypochondriasis", evaluated as single items on the Hamilton Depression Scale, and CSF-adrenaline concentrations, was found.
D000328:Adult; D000368:Aged; D001007:Anxiety / Q000134:cerebrospinal fluid; D003866:Depressive Disorder / Q000134:cerebrospinal fluid* / Q000150:complications; D004837:Epinephrine / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D006998:Hypochondriasis / Q000134:cerebrospinal fluid; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000134:cerebrospinal fluid*; D013001:Somatoform Disorders / Q000134:cerebrospinal fluid* / Q000150:complications
D009638:Norepinephrine; D004837:Epinephrine