Non-associative learning in the mouse. Effect of morphine and naloxone.
The study evaluates the effect of morphine and naloxone on the process of non-associative learning in the mouse. Exploratory behavior was measured in thirty-six male albino mice (Suisse) placed on a Boissier and Simon hole-board, the procedure being repeated 24 h later after administration of naloxone and/or morphine, or bidistilled water i.p. The results show that the inhibitory effect naloxone has on the recollection process of the mnemonic traces appears to be masked by morphine.
D000818:Animals; D005106:Exploratory Behavior; D007266:Inhibition, Psychological / Q000187:drug effects; D007858:Learning / Q000187:drug effects*; D008297:Male; D008568:Memory / Q000187:drug effects; D051379:Mice; D008815:Mice, Inbred Strains; D009020:Morphine / Q000494:pharmacology*; D009270:Naloxone / Q000494:pharmacology*
D009270:Naloxone; D009020:Morphine