[The polymorphism of drugs in powders and tablets. 5. Preparation and characterization of polymorphic forms of tolbutamide].
The preparation of 4 modifications and 2 spray dried products of tolbutamid is described. The characterization is performed by thermoanalytical methods (thermomicroscopy, DSC). Scanning electron microscopy and investigations of solubility complete the results.
D007700:Kinetics; D008855:Microscopy, Electron, Scanning; D011208:Powders; D012995:Solubility; D013055:Spectrophotometry, Infrared; D013607:Tablets; D014044:Tolbutamide / Q000008:administration & dosage
D011208:Powders; D013607:Tablets; D014044:Tolbutamide
Untersuchungen zur Polymorphie von Arzneistoffen in Pulvern und Tabletten. 5. Mitteilung: Zur Herstellung und Charakterisierung polymorpher Formen des Tolbutamids.