title: Ecdysteroids in vitro promote differentiation in the accessory glands of male mealworm beetles.
abstract: Physiological peak doses of 20-hydroxyecdysone were added to organ cultures of young pupal accessory glands of male Tenebrio molitor. During subsequent culture in vitro or in vivo, the glands accumulated adult-specific antigens. Control organ cultures showed no such antigen accumulation. In this system, ecdysteroid controls not only cell cycles but also differentiation.
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D046508:Culture Techniques; D004441:Ecdysterone / Q000494:pharmacology*; D008297:Male; D011679:Pupa / Q000033:anatomy & histology / Q000254:growth & development; D013712:Tenebrio / Q000033:anatomy & histology* / Q000187:drug effects / Q000254:growth & development
chemical_list: D004441:Ecdysterone