title: [Sinus histiocytosis with extensive adenopathy in a Mali child].
abstract: Destombes, Rosai and Dorfman's sinus histiocytosis (HS) is a rare disease. Many cases have been reported in Africans, particularly in children. Case reported here is the second malian clinical report. Its particularities are difficulties for the histological diagnosis with confusion with Hodgkin's disease, a temporary decrease of adenopathies after vincristine therapy, an eosinophilic infiltrate of lymph nodes and a long evolution during at least 4 years. The pathological physiology of HS remains uncertain. The benign natural course of the disease does not justify employment of chemotherapy.
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D008302:Mali; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine
vernacular_title: Histiocytose sinusale avec adénopathies massives chez un enfant malien.