title: Human experimentation in perinatology.
abstract: Perinatal medicine is developing at an amazingly rapid pace. The brilliant record has been marred by recurrent tragedies following the general use of well-meaning, but poorly evaluated, therapeutic regimens for newborn infants and pregnant women. There is a clear and present need for increased public clamor demanding carefully designed, risk-limiting human experiments (randomized clinical trials) to provide interpretable evidence of benefit and risks of innovations before these are adopted as desirable medical and social policy.
mesh_terms: D035061:Control Groups; D004992:Ethics, Medical; D006805:Human Experimentation; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000628:therapy*; D018579:Patient Selection; D010500:Perinatology; D037841:Pregnant People; D035842:Research Subjects; D018570:Risk Assessment