title: Challenge tests and specific IgE in hay fever sufferers.
abstract: The relationship between challenge tests, specific IgE and seasonal effects in hay fever sufferers was studied. There were significant relationships between nasal challenge, conjunctival challenge and skin-prick test threshold doses, although the skin and conjunctiva tended to be less sensitive than the nose. A seasonal effect was apparent on nasal challenge, but not conjunctival challenge or skin-prick testing, with lower threshold doses recorded after the pollen season than in midwinter. There was a significant relationship between specific IgE and nasal challenge, but not conjunctival or skin-prick test threshold doses.
mesh_terms: D000293:Adolescent; D000328:Adult; D000918:Antibody Specificity; D003228:Conjunctiva / Q000276:immunology; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D007159:Immunologic Tests; D008297:Male; D009299:Nasal Provocation Tests; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*; D012621:Seasons; D012882:Skin Tests
chemical_list: D007073:Immunoglobulin E