Melnick-Needles syndrome in males.
Melnick-Needles syndrome is an X-linked dominant trait, lethal in males. There are three well-documented lethal examples of the disorder in the offspring of affected females and three examples in males born to normal parents who represent new mutations.
D002675:Child, Preschool; D005145:Face / Q000002:abnormalities; D005799:Genes, Dominant; D005804:Genes, Lethal; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D010009:Osteochondrodysplasias / Q000000981:diagnostic imaging / Q000235:genetics*; D011859:Radiography; D014960:X Chromosome