Amiodarone pulmonary toxicity presenting as bilateral exudative pleural effusions.
Therapy with the antiarrhythmic drug amiodarone has been associated with drug-related side effects. In addition to pulmonary fibrosing alveolitis, anecdotal reports have alluded to incidental pleural involvement associated with amiodarone. We describe an unusual manifestation of amiodarone-induced pulmonary toxicity in a patient with bilateral exudative pleural effusions and toxic involvement of other organs. We review amiodarone-associated pleural reactions reported in the literature.
D000638:Amiodarone / Q000633:toxicity*; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010994:Pleura / Q000187:drug effects / Q000473:pathology; D010996:Pleural Effusion / Q000139:chemically induced*; D010998:Pleurisy / Q000139:chemically induced*
D000638:Amiodarone