title: [Dosimetric characteristics of internal irradiation with radioactive nuclides of iodine].
abstract: The paper is concerned with some data on mean absorbed dose values in the animals' organs, the time course of their formation and the character of microdistribution of an absorbed dose around thyroid follicles in internal irradiation of the rat body with 131I and 125I. A raised level of irradiation of the animals' pituitary body is noted. The authors provide dosimetric characteristics of irradiation of thyroid microstructures noting that 125I creates more inhomogeneous distribution of an absorbed dose around thyroid follicles compared to 131I, irradiating, to a greater extent, the follicular membrane and, to a lesser degree, the nuclei of surrounding cells whereas 131I provides homogeneous irradiation of thyroid cells. The authors give a comparative critical analysis of the quantitative and microdosimetric characteristics and literature data.
mesh_terms: D000042:Absorption; D000818:Animals; D001610:Beta Particles; D004583:Electrons; D007457:Iodine Radioisotopes / Q000378:metabolism*; D010902:Pituitary Gland / Q000378:metabolism; D011874:Radiometry; D051381:Rats; D013961:Thyroid Gland / Q000378:metabolism; D013997:Time Factors; D014018:Tissue Distribution
chemical_list: D007457:Iodine Radioisotopes
vernacular_title: Dozimetricheskie kharakteristiki vnutrennego oblucheniia radioaktivnymi nuklidami ĭoda.