title: Emotional eccrine sweating. A heritable disorder.
abstract: A family with hereditary emotional hyperhidrosis is described. The inheritance pattern is autosomal dominant. A simple quantitative palmar sweat test was used to objectively confirm historical data. Of two family members tested, both had a marked decrease in palmar sweat secretion during administration of diltiazem, a calcium-channel blocker. Additional studies in a large group of patients are needed to extend this observation.
mesh_terms: D000293:Adolescent; D000328:Adult; D004110:Diltiazem / Q000494:pharmacology / Q000627:therapeutic use; D004439:Eccrine Glands / Q000187:drug effects; D005260:Female; D006801:Humans; D006945:Hyperhidrosis / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D013315:Stress, Psychological; D013542:Sweat / Q000032:analysis
chemical_list: D004110:Diltiazem