A new antitumor antibiotic, FR-900482. I. Taxonomic studies on the producing strain: a new species of the genus Streptomyces.
A new species in the genus Streptomyces, for which the name Streptomyces sandaensis sp. nov. is proposed, is described. Soil isolate strain No. 6897 (FERM-P 7654), produces a new antitumor substance FR-900482. The strain has a gray to red spore mass color, Rectus Flexibilis to Retinaculum-Apertum spore chain morphology, smooth spores, and is nonchromogenic. Strain No. 6897 is closely related to Streptomyces aburaviensis and Streptomyces nitrosporeus. But, there are many differences in cultural characteristics and in the utilization of carbohydrates.
D000903:Antibiotics, Antineoplastic / Q000032:analysis*; D001643:Bridged Bicyclo Compounds / Q000032:analysis; D002244:Carbon / Q000378:metabolism; D002473:Cell Wall / Q000032:analysis; D003470:Culture Media; D010078:Oxazines; D012988:Soil Microbiology; D013171:Spores, Bacterial / Q000032:analysis; D013302:Streptomyces / Q000032:analysis* / Q000145:classification / Q000502:physiology
D000903:Antibiotics, Antineoplastic; D001643:Bridged Bicyclo Compounds; D003470:Culture Media; D010078:Oxazines; C053335:FR 900482; D002244:Carbon