Supernumary marker chromosomes in a mentally retarded population identified as inv dup(15).
Bisattelited supernumary chromosomes, identified as inv dup(15)s, were detected at a prevalence of 8/1000 among institutionalized, mentally retarded (non-Down syndrome) males. This finding suggests that the inv dup(15) contributes significantly to the etiology of mental retardation among institutionalized individuals.
D002871:Chromosome Banding; D002884:Chromosomes, Human, Pair 15; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics* / Q000473:pathology; D007621:Karyotyping; D008297:Male; D009697:Nucleolus Organizer Region; D013737:Testis / Q000473:pathology