Thin-layer chromatographic analysis of phenolic age resisters in elastomers in contact with the body, drugs and foods.
Phenolic antioxidants were identified by thin-layer chromatography in 102 samples of medical and pharmaceutical rubber articles. Acetone extracts of rubber were spotted on silica gel plates with a concentrating zone. Benzene, benzene-hexane (75:25) and benzene-ethyl acetate-acetone (100:5:1) were used as developing solvents and N-chloro-2,6-dichloro-p-benzoquinone monoimine as spray reagent. Only 8 sterically hindered phenols among the 57 previously listed were found in current use. Reasons for choosing these compounds and the experimental conditions are discussed.
D000975:Antioxidants / Q000032:analysis* / Q000097:blood; D002855:Chromatography, Thin Layer; D005504:Food Analysis; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis; D010636:Phenols / Q000032:analysis* / Q000097:blood; D012408:Rubber / Q000032:analysis*
D000975:Antioxidants; D004364:Pharmaceutical Preparations; D010636:Phenols; D012408:Rubber