title: Intralaryngeal barriers to the spread of cancer.
abstract: Serial section studies were made of 412 surgical specimens removed by partial or total laryngectomy for laryngeal cancer. All sections were stained with hematoxylin and eosin. Selected sections were also stained for elastic tissue. Patterns of growth and spread of cancer within the larynx were found to be influenced by fibro-elastic ligaments and membranes which confined the tumor to anatomic compartments, and which provide margins of safety when performing partial laryngectomy.
mesh_terms: D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000503:physiopathology; D007830:Larynx / Q000033:anatomy & histology* / Q000503:physiopathology