[Aggravating action of oxygen in light injury to the retina in the white rat].
Rhodopsin concentration and "a"-wave ERG decrease, depending on illumination in the range of 360-380 nm have been investigated in albino rats. The dose of 1.8 J/cm2 proved sufficient for a decrease of "a"-wave ERG by 70% and for the reduction in rhodopsin concentration by 80%. The substitution of the air for O2 (1 or 2.5 ata) resulted in a considerable increase of photodamage of the retina.
D000399:Air Pressure; D000818:Animals; D004596:Electroretinography; D008027:Light / Q000009:adverse effects*; D010100:Oxygen / Q000633:toxicity*; D010775:Photic Stimulation; D051381:Rats; D012160:Retina / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D012243:Rhodopsin / Q000378:metabolism / Q000528:radiation effects
D012243:Rhodopsin; D010100:Oxygen
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