Allo-anti-Chido in a Ch-positive patient.
Allo-anti-Chido (Ch) was detected in a patient whose red cells typed as Ch+. The C4 allotype of the patient was A4,B2 which associates strongly with the Ch phenotype Ch:1,-2,3,4,-5,6. Anti-Ch2 + Ch5 were the Ch specificities identified. Absence of only Ch2 and Ch5 determinants on the C4B protein allowed this unique immune response to blood transfusion.
D000368:Aged; D001789:Blood Group Antigens / Q000235:genetics / Q000276:immunology*; D003181:Complement C4 / Q000235:genetics / Q000276:immunology; D005260:Female; D006239:Haplotypes; D006801:Humans; D007518:Isoantibodies / Q000276:immunology*; D008297:Male; D010375:Pedigree; D010641:Phenotype
D001789:Blood Group Antigens; D003181:Complement C4; D007518:Isoantibodies