Kininase I activity in human fluids and tissues of the urogenital tract.
Kininase I (EC 3.4.17.3) activity has been determined in human fluids and tissues of the urogenital tract. Benzoyl-glycyl-L-arginine and benzoyl-glycyl-L-lysine were used as substrates. The cleaved benzoyl-glycine was measured by means of high performance liquid chromatography. Results obtained showed a high enzymatic activity for kidney cortex. Normal prostate, benign prostatic hyperplasia and prostatic adenocarcinoma showed similar enzymic values. The activity of kininase I was higher in normal serum than in the tissues studied.
D002268:Carboxypeptidases / Q000378:metabolism*; D006801:Humans; D007668:Kidney / Q000201:enzymology; D001121:Lysine Carboxypeptidase / Q000378:metabolism*; D008297:Male; D011467:Prostate / Q000201:enzymology; D012661:Semen / Q000201:enzymology; D013737:Testis / Q000201:enzymology; D001743:Urinary Bladder / Q000201:enzymology; D014566:Urogenital System / Q000201:enzymology*
D002268:Carboxypeptidases; D001121:Lysine Carboxypeptidase