Serum aldolase isoenzymes in benign and malignant liver disease.
Using a radio-immunoassay, aldolase A and B isoenzyme concentrations have been measured in the sera of patients in order to assess their specificity and sensitivity in a variety of hepatic disorders. Serum aldolase A has been confirmed to be elevated in some patients with malignant infiltration of the liver, but its sensitivity is not sufficient to be of clinical value. Aldolase B is a sensitive marker of liver cell damage which correlates closely with conventional biochemical markers of inflammation. It appears to distinguish successfully between hepatic and cardiac damage.
D005634:Fructose-Bisphosphate Aldolase / Q000097:blood*; D006801:Humans; D008099:Liver / Q000201:enzymology; D008107:Liver Diseases / Q000175:diagnosis / Q000201:enzymology*; D009132:Muscles / Q000201:enzymology; D009203:Myocardial Infarction / Q000175:diagnosis / Q000201:enzymology
D005634:Fructose-Bisphosphate Aldolase