Overlap myasthenic syndrome: combined myasthenia gravis and Eaton-Lambert syndrome.
A patient with a known history of pernicious anemia had the combined features of autoimmune myasthenia gravis (MG) and the Eaton-Lambert syndrome (ELS). Initially, this patient had all the features typical of MG, and after thymectomy developed all the typical features of ELS. In view of the coexistence of two autoimmune neuromuscular transmission disorders in one patient, we termed this disorder "overlap myasthenic syndrome."
D000200:Action Potentials; D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D004576:Electromyography; D005260:Female; D006801:Humans; D009132:Muscles / Q000473:pathology / Q000503:physiopathology; D009157:Myasthenia Gravis / Q000150:complications* / Q000503:physiopathology; D009431:Neural Conduction; D009468:Neuromuscular Diseases / Q000150:complications* / Q000503:physiopathology; D011950:Receptors, Cholinergic / Q000032:analysis
D001323:Autoantibodies; D011950:Receptors, Cholinergic