title: High performance liquid chromatography assay for piroxicam in pharmaceutical products.
abstract: A high performance liquid chromatographic assay for piroxicam in pharmaceutical preparations is described. The method uses a reversed-phase C18 column with pH 3 aqueous buffer/methanol, 55:45, v/v mobile phase, and is selective for piroxicam in the presence of other "oxicams," synthetic precursors, by-products, degradation products, metabolites, and related compounds. Applications to capsules, tablets, ointments, suppositories, ophthalmic suspensions, and rodent feeds are cited.
mesh_terms: D000821:Animal Feed / Q000032:analysis; D002214:Capsules; D002851:Chromatography, High Pressure Liquid; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D009824:Ointments; D009883:Ophthalmic Solutions; D010894:Piroxicam / Q000008:administration & dosage / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet; D013488:Suppositories
chemical_list: D002214:Capsules; D009824:Ointments; D009883:Ophthalmic Solutions; D013488:Suppositories; D010894:Piroxicam