Microarterial sutureless sleeve anastomosis using a polymeric adhesive: an experimental study.
A new technique for microarterial sutureless anastomosis that involves telescoping one vessel into the other and placing a microdrop of a polymeric adhesive (iso-propyl-cyanoacrylate) is described. Sixty-six anastomoses were performed in rat femoral arteries with a patency rate of 95 percent. Light and electron microscopic studies were conducted at regular intervals, starting immediately to 90 days postoperative. From this experimental study, it appears that the described method of anastomosis is faster and easier to perform and at least as reliable as the conventional end-to-end suture anastomosis. In addition, it was observed that tissue reaction to the glue remained primarily adventitial and did not disturb vessel patency.
D000818:Animals; D003487:Cyanoacrylates / Q000627:therapeutic use*; D005263:Femoral Artery / Q000601:surgery / Q000648:ultrastructure; D006083:Graft Occlusion, Vascular / Q000209:etiology; D008866:Microsurgery / Q000379:methods*; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains; D013518:Surgery, Plastic / Q000379:methods*; D014014:Tissue Adhesives / Q000627:therapeutic use*
D003487:Cyanoacrylates; D014014:Tissue Adhesives; C052923:isopropyl cyanoacrylate