title: [Treatment of acute arterial embolism of the kidney].
abstract: The possible ways of treating renal artery embolisms are reviewed with an examination of their advantages and defects. Surgical treatment has a fairly high mortality rate but quickly cures any type of vascular occlusion and will cure any concomitant problems such as arterial stenosis. Medical treatment with anticoagulant or thrombolytic drugs offers a lower short term mortality rate and is effective even on narrow blood vessels but the response varies according to the type of thromboembolic damage and the way the drugs are administered. Recently developed forms of radiological treatment are also examined. A personal technique successfully applied to an embolism in a patient with only one functioning kidney is described. It consists of a two-step mechanical and pharmacological attack. First the occluded artery was opened by means of a balloon catheter that was pushed beyond the embolism and withdrawn into the aorta after inflation of the balloon. Thrombolytic drugs (Urokinase) were then infused through the catheter into the bed of the renal artery in order to cure the secondary thrombosis found, as is generally the case, downstream of the embolism. The technique appears ideal for the treatment of patients with embolisms and total involvement of the renal parenchyma, especially when their general condition makes surgery inadvisable.
mesh_terms: D002404:Catheterization / Q000295:instrumentation; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011859:Radiography; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000628:therapy*; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000628:therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Sul trattamento dell'embolia arteriosa acuta del rene.