Lymphocytic hypophysitis.
A patient with a chronic lymphocytic hypophysitis (LYHY) following an idiopathic lymphocytic meningitis is described. Computed tomography scan of the sella turcica suggested a pituitary adenoma with suprasellar extension, whereas hormonal investigations showed a functional lesion at the suprapituitary level. A transsphenoidal biopsy revealed diffuse lymphocytic infiltration of the adenohypophysis without characteristics of a sarcoid lesion. The possible relationship between idiopathic (viral?) lymphocytic meningitis and LYHY is discussed.
D001323:Autoantibodies / Q000032:analysis; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology; D008214:Lymphocytes / Q000473:pathology*; D008581:Meningitis / Q000150:complications*; D008875:Middle Aged; D010900:Pituitary Diseases / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D010903:Pituitary Gland, Anterior / Q000473:pathology
D001323:Autoantibodies