title: [Cytogenetic effect of 238Pu alpha radiation on the germ cells of male mice].
abstract: A study was made of the yield of reciprocal translocations in stem spermatogonia of mice exposed to alpha-radiation (238Pu) and whole-body acute and chronic gamma-radiation within a wide range of doses and dose-rates. The frequency of reciprocal translocations induced by a single intraperitoneal administration of plutonium nitrate was relatively low and independent of the dose 1.5-18 months after the effect. The yield of the reciprocal translocations induced by chronic effect of gamma-radiation was appreciably lower than that observed after acute irradiation with the same dose and grew linearly with dose. The RBE of alpha-radiation was 10-20 with respect to chronic effect of gamma-radiation.
mesh_terms: D000512:Alpha Particles; D000818:Animals; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011005:Plutonium / Q000494:pharmacology*; D013094:Spermatozoa / Q000528:radiation effects*; D013997:Time Factors; D014178:Translocation, Genetic / Q000528:radiation effects
chemical_list: D011005:Plutonium
vernacular_title: Tsitogeneticheskiĭ éffekt al'fa-izlucheniia 238Pu v polovykh kletkakh samtsov myshi.