Influence of hexachlorobenzene on thyroids of male hamsters.
The effect of hexachlorobenzene (HCB) on thyroid function in hamsters was explored and compared with that of 3-amino-1,2,4-triazole. Both chemicals caused thyroid enlargement but whereas 3-amino-1,2,4-triazole depressed serum thyroxine (T4) levels and elevated triiodothyronine (T3), HCB depressed T3 with little effect on T4.
D000818:Animals; D002722:Chlorobenzenes / Q000633:toxicity*; D006224:Cricetinae; D006581:Hexachlorobenzene / Q000633:toxicity*; D008297:Male; D008647:Mesocricetus; D013961:Thyroid Gland / Q000187:drug effects*; D013963:Thyroid Hormones / Q000097:blood
D002722:Chlorobenzenes; D013963:Thyroid Hormones; D006581:Hexachlorobenzene