title: [Clinico-pathogenetic variants of protracted forms of acute myocardial infarct].
abstract: Methods of clinico-instrumental investigation and biochemical monitoring (CPK and its membranous fraction) were employed for examination of 432 patients with acute myocardial infarction (AMI). Among them there were patients with an uncomplicated course of disease (19.4%), recurrences (13.7%) and AMI spreading (9%). Lung edema, a cardiogenic shock, ventricular fibrillation and complicated cardiac rhythm disorders were not detected on the 1st day of disease. Clinico-anamnestic data provided no opportunity for defining factors promoting AMI recurrences whereas AMI spreading frequently developed in patients with repeated AMI, suffering from essential hypertension, obesity and heart failure. Higher diastolic pressure in the pulmonary artery, an increase in the cardiac volume, a decrease in the ejection fraction and left ventricular stroke work--changes which were most pronounced in AMI spreading, were noted in patients with AMI lingering forms. Signs of disseminated intravascular blood coagulation were noted in the venous and arterial blood of patients with lingering AMI forms. A high blood enzyme level was shown to be accompanied by a low level of antibodies to LDH and CPK.
mesh_terms: D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis; D001780:Blood Coagulation Tests; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood / Q000276:immunology; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood / Q000276:immunology; D008875:Middle Aged; D009203:Myocardial Infarction / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D012008:Recurrence; D013997:Time Factors
chemical_list: D000906:Antibodies; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase
vernacular_title: Kliniko-patogeneticheskie varianty zatiazhnykh form ostrogo infarkta miokarda.