Muscle morphology with special reference to muscle strength in post-polio subjects.
The main histopathologic finding is large grouping of type I and type II fibers. Subjects with low muscle strength had a large number of type I fibers. Large fibers were found especially in men with low muscle strength. The oxidative enzymatic activity was reduced. The findings suggest a compensatory process, with an increased number of type I fibers in subjects, a large reduction in muscle strength, and also an increase in the fiber size. There is a sex difference in the fiber hypertrophy.
D000328:Adult; D001706:Biopsy; D002950:Citrate (si)-Synthase / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000201:enzymology / Q000473:pathology / Q000503:physiopathology*; D009135:Muscular Diseases / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D011051:Poliomyelitis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D012737:Sex Factors
D002950:Citrate (si)-Synthase