Retrovirus-like particles in embryonic kidney tissue of the platyfish, Xiphophorus maculatus.
Ultrastructural studies were performed on embryos of an inbred strain (163A) of the platyfish Xiphophorus maculatus, and a pooled stock of the Rio Sarabia strain of the swordtail, X. helleri. Viral-like particles were found in the kidney tissue of platyfish embryos. Exposure of pregnant platyfish to 5-bromodeoxyuridine during the time of differentiation of embryonic melanocytes enhanced the production of viral-like particles in platyfish embryos. Viral-like particles were not found in untreated or drug-treated swordtail embryos. The morphology of these particles corresponds to type C retroviruses.
D000818:Animals; D001973:Bromodeoxyuridine / Q000494:pharmacology; D003532:Cyprinodontiformes / Q000382:microbiology*; D004625:Embryo, Nonmammalian / Q000382:microbiology; D007668:Kidney / Q000196:embryology / Q000382:microbiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008928:Mitochondria / Q000187:drug effects / Q000648:ultrastructure; D012190:Retroviridae / Q000302:isolation & purification / Q000648:ultrastructure*
D001973:Bromodeoxyuridine