title: [Lipoprotein lipase activity in the tissues of roosters fed hyperlipemic diet with or without L-ascorbic acid in 2 phases of the circadian rhythm].
abstract: The activity of lipoproteide lipase in tissues of sexually immature cocks fed hiperlipaemic diet (cholesterol + animal fat) and an identical diet with the addition of 1-ascorbic acid was determined in two phases of a day rhythm. After 21 days of the experiment it was found statistically significant increase the activity of the examined enzyme in the group of animals fed cholesterol and animal fat an average by 37.8% in lungs, 76.7% in fatty tissue and by 19.0% in kidneys in comparison to controls (a standard diet). In group of cocked fed hiperlipaemic diet with 1-ascorbic acid the activity of lipoproteide lipase was also higher in comparison to controls, but it was lower than in cocks deprived of this compound by 14.7% in lungs, 41.4% in fatty tissue and by 7.9% in kidneys. These differences were statistically significant. Statistically significant appeared also to be the increased activity of this enzyme in groups sacrified at 4 am in comparison to those sacrified at 4 pm an average by 65.8% in controls, by 64.4% in group fed hiperlipaemic diet and by 69.9% in group fed diet with 1-ascorbic acid. In fatty tissue these values were higher by 53.9%, 177.5% and 138.9% and in kidneys by 50.7%, 22.8% and 40.4% respectively. It was also found significant increase of the activity of this enzyme in fatty tissue in the two experimental groups in comparison to controls by 114.4% and 71.9%, respectively. The observed changes may be explained acc. to the rules of a general adaptative syndrome of Seyle or as adaptative mechanisms acting on molecular level.
mesh_terms: D000273:Adipose Tissue / Q000201:enzymology; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage*; D002645:Chickens / Q000378:metabolism*; D004041:Dietary Fats / Q000008:administration & dosage*; D004789:Enzyme Activation; D008071:Lipoprotein Lipase / Q000378:metabolism*; D008297:Male
chemical_list: D004041:Dietary Fats; D008071:Lipoprotein Lipase; D001205:Ascorbic Acid
vernacular_title: Aktywność lipazy lipoproteidowej w tkankach kogutów zywionych dieta hiperlipemizujaca bez i z dodatkiem kwasu l-askorbowego w dwu fazach rytmu dobowego.