[Pharmacokinetics of 99m Tc-technephyte in radionuclide studies of the liver and spleen].
The authors present the results of an experimental study of pharmacokinetics of a new Soviet drug 99 mTc-technephyte for scintigraphy of the liver and spleen. The results of biological distribution of the agent in rat, scintigrams of the liver and spleen in rabbits and dogs have shown a high accumulation of 99 mTc-technephyte in the liver (up to 90%). The agent is prepared within one stage from a kit of reagents and 99m-sodium pertechnetate obtained using a generator.
D000818:Animals; D004285:Dogs; D007700:Kinetics; D008099:Liver / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds / Q000378:metabolism; D015609:Organotechnetium Compounds; D010833:Phytic Acid / Q000378:metabolism; D011817:Rabbits; D011877:Radionuclide Imaging; D051381:Rats; D013154:Spleen / Q000000981:diagnostic imaging*; D013667:Technetium / Q000378:metabolism; D014018:Tissue Distribution
D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; C053377:technetium Tc 99m technephyte; D013667:Technetium; D010833:Phytic Acid
Farmakokinetika 99mTc-tekhnefita pri radionuklidnykh issledovaniiakh pecheni i selezenki.