The isolation of influenza virus from chickens in Israel and studies on its antigenic relationships with other native isolates of the same antigenicity by means of monoclonal antibodies.
A hemagglutinating (HA) agent isolated from an outbreak of a respiratory disease in a kibbutz broiler farm was identified as influenza virus A/chicken/Degania, Israel/80(H7N2). Investigation using a panel of 5 monoclonal antibodies against H7 antigenic subtype has shown substantial difference of the isolate from the other H7-containing influenza viruses isolated in Israel. Antigenic relationships between the native H7-containing strains revealed by means of the monoclonal antibodies led to re-evaluation of the suggested views on local epizootiology and interspecies transfer of avian influenza.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis*; D002642:Chick Embryo; D002645:Chickens; D006385:Hemagglutination Inhibition Tests; D009980:Influenza A virus / Q000276:immunology* / Q000302:isolation & purification; D005585:Influenza in Birds / Q000382:microbiology*; D007557:Israel
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral