Diurnal variation in the excretion of 6 beta-hydroxycortisol and estriol at 32 weeks gestation.
We have previously shown a marked diurnal variation in the excretion of cortisol and 6 beta-hydroxycortisol at 36-38 weeks pregnancy with no variation in estrogen excretion. Since others have shown a reciprocal relationship between plasma levels of estriol and cortisol at 30-35 weeks of pregnancy, we decided to determine whether a similar relationship was present in urinary concentrations of cortisol, 6 beta-hydroxycortisol and estriol at this gestational age. A significant variation in excretion of both cortisol and 6 beta-hydroxycortisol was found. The variation in urinary levels of estriol was less than that of the corticosteroids but followed the same pattern.
D002940:Circadian Rhythm; D004964:Estriol / Q000652:urine*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000031:analogs & derivatives* / Q000652:urine; D011247:Pregnancy / Q000652:urine*; D011263:Pregnancy Trimester, Third
C001380:6 beta-hydroxycortisol; D004964:Estriol; D006854:Hydrocortisone