[Dependence of the intensity of the immune response on the characteristics of the formation of a Salmonella typhi antigen depot on erythrocytes].
Experiments on inbred mice, opposite in the capacity of their erythrocytes for the sorption of S. typhi antigens, have revealed that the intensity of immune response to the antigens depends on the functional potency of immunocompetent cells and the conditions of their priming. The optimal manifestations of the conditions for lymphocyte priming depends on the character of the antigen fixation by erythrocytes and antigen supply from the depot into the blood stream.
D000327:Adsorption; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000937:Antigen-Antibody Reactions; D000942:Antigens, Bacterial / Q000276:immunology*; D004306:Dose-Response Relationship, Immunologic; D004912:Erythrocytes / Q000276:immunology*; D007114:Immunization; D008213:Lymphocyte Activation; D051379:Mice; D008815:Mice, Inbred Strains; D012485:Salmonella typhi / Q000276:immunology*; D013997:Time Factors
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Zavisimost' vysoty immunnogo otveta ot osobennosteĭ formirovanniia depo antigenov Salmonella typhi na éritrotsitakh.