title: Benzydamine, an unique model of anti-inflammatory activity.
abstract: Benzydamine is an anti-inflammatory drug with unique medical uses, namely the topical treatment of oro-pharyngeal and gynaecological conditions. This paper illustrates the rationale for the medical use of benzydamine. Its differences from aspirin-like drugs are pointed out, and evidence is presented that benzydamine does not primarily affect the PGs system, but rather reduces the cell response to injury.
mesh_terms: D000779:Anesthetics, Local; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin / Q000494:pharmacology / Q000633:toxicity; D001591:Benzydamine / Q000494:pharmacology* / Q000633:toxicity; D007249:Inflammation / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects; D011720:Pyrazoles / Q000494:pharmacology*
chemical_list: D000779:Anesthetics, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011720:Pyrazoles; D001591:Benzydamine; D001241:Aspirin