Sperm chymotrypsin-like enzymes of different inhibitor-susceptibility as lysins in ascidians.
Inhibitory effects of three peptidyl phenylalaninals on fertilization and on chymotrypsin-like enzyme activity of sperm in three species of ascidians were examined. The results suggest that a sperm chymotrypsin-like enzyme is indispensable for the fertilization in each of the ascidians, and that these enzymes have different susceptibilities to inhibitors.
D000818:Animals; D000900:Anti-Bacterial Agents; D002918:Chymotrypsin / Q000037:antagonists & inhibitors / Q000502:physiology*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005306:Fertilization / Q000187:drug effects; D007976:Leupeptins / Q000494:pharmacology; D008297:Male; D009842:Oligopeptides / Q000494:pharmacology; D010455:Peptides; D013094:Spermatozoa / Q000201:enzymology*; D014561:Urochordata / Q000502:physiology*
D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D007976:Leupeptins; D009842:Oligopeptides; D010455:Peptides; C038356:microbial alkaline proteinase inhibitor; C002101:chymostatin; D002918:Chymotrypsin; C032854:leupeptin