A carpipramine related fatality.
A fatality following ingestion of the tricyclic antidepressant carpipramine (Prazinil) and ethyl alcohol is described. Carpipramine was quantitated by high performance liquid chromatography. The concentration of carpipramine was 2.0 mg/L in blood and 0.44 mg/L in urine. Ethyl alcohol was measured by headspace gas chromatography and found to be 105 mg/dL in blood and 55 mg/dL in the urine. Quantitative analysis of stomach contents was positive for carpipramine by thin-layer chromatography. To our knowledge, this is the first reported fatality involving carpipramine.
D000428:Alcohol Drinking; D014151:Anti-Anxiety Agents; D000929:Antidepressive Agents, Tricyclic / Q000097:blood / Q000506:poisoning* / Q000652:urine; D001569:Benzodiazepines; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D003984:Dibenzazepines / Q000097:blood / Q000506:poisoning* / Q000652:urine; D006801:Humans; D008297:Male
D014151:Anti-Anxiety Agents; D000929:Antidepressive Agents, Tricyclic; D003984:Dibenzazepines; D001569:Benzodiazepines; C006922:carpipramine