title: [Hearing loss, a complication of antibiotic therapy in severely burned patients].
abstract: Two severely burned patients became virtually deaf during the course of treatment. The systemic and local applications of aminoglycosides and the high dosage of furosemide were the probable ototoxic agents. Renal insufficiency and persistent shock were enhancing agents. None of these factors were felt to be the individual cause of the complication, but in combination were felt to cause the deafness.
mesh_terms: D000328:Adult; D000617:Aminoglycosides / Q000009:adverse effects* / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002056:Burns / Q000188:drug therapy*; D003404:Creatinine / Q000097:blood; D005260:Female; D005665:Furosemide / Q000009:adverse effects; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced*; D006801:Humans; D008297:Male
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D005665:Furosemide; D003404:Creatinine
vernacular_title: Schwerhörigkeit, eine Komplikation der Antibiotikatherapie bei Schwerverbrannten.