Pregnancy among patients with systemic lupus erythematosus receiving immunosuppressive therapy.
We evaluated retrospectively the effect of superimposed pregnancy upon the course of systemic lupus erythematosus (SLE) in patients receiving glucocorticoids or azathioprine at conception. About equal numbers of flares (10 vs 12) occurred among 22 pregnant patients with lupus and 22 nonpregnant control patients with lupus matched by disease duration and prior organ system involvement. Pregnancy per se did not appear to accelerate SLE in patients receiving immunosuppressive therapy.
D001379:Azathioprine / Q000627:therapeutic use; D003401:Creatine / Q000097:blood; D005260:Female; D005306:Fertilization; D006801:Humans; D007165:Immunosuppression Therapy; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors
D001379:Azathioprine; D003401:Creatine; D011241:Prednisone