title: Origin of high-grade superficial bladder cancer.
abstract: The study of 12 patients with superficial G3 bladder carcinoma shows a high incidence of carcinoma in situ in the flat mucosa (66.6%, p less than 0.001), with a polypoid growth pattern (58.3%) and an evolution similar to isolated carcinoma in situ of the bladder. These data support the hypothesis that this variant of tumor is the expression of a vesical carcinoma in situ diagnosed at the time of intraluminal growth and therefore with its own capacity to become an infiltrative carcinoma.
mesh_terms: D000328:Adult; D000368:Aged; D002278:Carcinoma in Situ / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000473:pathology*