title: Wilson's disease, a reversible dementia: case report.
abstract: A case of advanced Wilson's disease with clear dementing features is presented. Neuropsychological evaluation before treatment revealed intellectual deterioration particularly in memory and performance tasks. The patient was treated with Penicillamine, a copper-chelating agent, for 7 months, with notable improvement in her dementia and in her motor signs. A second battery of neuropsychological tests demonstrated the improvement in the mental aspects. These findings support the concept of Wilson's disease being a reversible dementia.
mesh_terms: D000328:Adult; D003704:Dementia / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D005260:Female; D006527:Hepatolenticular Degeneration / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D009483:Neuropsychological Tests; D010396:Penicillamine / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D010396:Penicillamine