[Long-term hypertransaminasemia disclosing a muscular disease].
Prolonged increase in serum transaminase activity is usually seen in chronic liver disease. Evaluation in one patient with such a prolonged increase having no evidence of liver disease including histological examination, revealed a limb girdle muscular dystrophy. This case suggests that a muscular disease should be suspected in all children with persistent increase in serum transaminase activity when the liver is apparently normal.
D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood; D004576:Electromyography; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D009136:Muscular Dystrophies / Q000097:blood / Q000201:enzymology*; D000637:Transaminases / Q000097:blood*
D007770:L-Lactate Dehydrogenase; D000637:Transaminases; D003402:Creatine Kinase; D005634:Fructose-Bisphosphate Aldolase
Hypertransaminasémie prolongée révélatrice d'une myopathie.