title: Gastrin in pituitary tumours.
abstract: Twelve of 87 pituitary adenomas from patients with acromegaly, Cushing's syndrome. Nelson's syndrome, hyperprolactinaemia and without symptoms of hormone hypersecretion contained gastrin in concentrations from 0.5 to 166 pmol/g. Only ACTH-producing tumours contained gastrin, which occurred in forms smaller than those present in the normal adenohypophysis. The results indicate that corticotropic tumours may synthesize gastrin in moderate amounts.
mesh_terms: D000236:Adenoma / Q000032:analysis*; D002850:Chromatography, Gel; D005755:Gastrins / Q000032:analysis*; D006801:Humans; D008968:Molecular Conformation; D010903:Pituitary Gland, Anterior / Q000032:analysis; D010911:Pituitary Neoplasms / Q000032:analysis*; D011863:Radioimmunoassay
chemical_list: D005755:Gastrins