Sensitization to methylenedianiline and para-structures.
A toxic-allergic skin reaction of the face, neck and arms due to accidental contact with methylenedianiline (syn: 4-4'-diaminodiphenylmethane) is reported in a cleaner at a chemical plant. Patch tests revealed sensitization to chemicals of the para-group. Earlier exposure to it was unlikely. Previous sensitization to related chemicals and possible cross-sensitization was considered to be the primary cause of the allergy and the clinical manifestations.
D000328:Adult; D000814:Aniline Compounds / Q000009:adverse effects*; D003429:Cross Reactions; D003877:Dermatitis, Contact / Q000209:etiology*; D006801:Humans; D008297:Male; D012882:Skin Tests; D001559:Benzhydryl Compounds
D000814:Aniline Compounds; C009505:4,4'-diaminodiphenylmethane; D001559:Benzhydryl Compounds