Superior sulcus lung tumors. Results of combined treatment (irradiation and radical resection).
Twenty-one patients underwent combined therapy (irradiation and radical resection) for a Pancoast tumor at the Massachusetts General Hospital between 1976 and 1985. All patients underwent en bloc removal of the apical chest wall and underlying lung. In addition four patients required subclavian artery resection, and in five patients a portion of the vertebral body was resected. There were three operative deaths. Median survival was 24 months and actuarial survival rate was 55% at 3 years and 27% at 5 years. Long-term palliation of pain was achieved in 72% of the patients. Involvement of the subclavian artery, vertebral body, or rib did not preclude long-term survival. Computed tomographic scanning in these patients is often indeterminate regarding invasion of chest wall structures but is more helpful than plain films alone. When compared to recent series in which irradiation alone was used, the combined approach appears to produce better results.
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010178:Pancoast Syndrome / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D011013:Pneumonectomy; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D012272:Ribs / Q000601:surgery; D013997:Time Factors