Assessment of potential acute health effects in agricultural workers exposed during the application of chlordimeform.
Agricultural workers exposed to chlordimeform (Cdf) used as a pesticide on cotton in Imperial County, California, were monitored during the 1982 application season. Cdf metabolites were found in the urine of 132 workers and were positively correlated with the length of exposure and nature of job activity. Persons mixing and loading and engaged in miscellaneous tasks such as cleaning and maintenance of equipment had the greatest exposure. There was no evidence of urinary tract irritation by microscopic analysis of the urine, nor were significant differences found between preseason and postseason serum chemistry results. Despite the use of protective clothing and closed system transfer devices, Cdf was absorbed by workers as evidenced by urinary metabolite excretion.
D000382:Agricultural Workers' Diseases / Q000139:chemically induced*; D000578:Amidines / Q000009:adverse effects*; D002742:Chlorphenamidine / Q000009:adverse effects* / Q000652:urine; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008658:Inactivation, Metabolic; D008297:Male; D012306:Risk
D000578:Amidines; D002742:Chlorphenamidine