title: Heterogeneity of postnatal development of ACh levels in brain regions of the mouse.
abstract: Acetylcholine (ACh) was measured from birth to the 78th day in 11 mouse brain regions. Three patterns of development emerged: ACh increased rapidly, overshot and returned to the adult level in midbrain-medulla-pons and cerebellum, ACh increased linearly to adult level in neostriatum and olfactory bulb and ACh increased linearly to a plateau and then increased to the adult level in the remaining regions.
mesh_terms: D000109:Acetylcholine / Q000032:analysis*; D000110:Acetylcholinesterase / Q000032:analysis; D000375:Aging / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000254:growth & development; D001923:Brain Chemistry; D002795:Choline O-Acetyltransferase / Q000032:analysis; D051379:Mice; D008815:Mice, Inbred Strains; D009419:Nerve Tissue Proteins / Q000032:analysis
chemical_list: D009419:Nerve Tissue Proteins; D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase; D000109:Acetylcholine