An unusual case of central nervous system vasculitis.
A patient with CNS vasculitis limited to small vessels is described. Initial spinal cord involvement with paraparesis was followed by multifocal cerebral and cerebellar involvement, depicted by magnetic resonance imaging (MRI). She also had recurrent cerebral bleeding. A diagnosis of vasculitis was made by cerebral biopsy. Immunosuppressive therapy resulted in clinical improvement and resolution of the MRI abnormalities.
D001706:Biopsy; D001921:Brain / Q000098:blood supply / Q000473:pathology*; D002490:Central Nervous System / Q000098:blood supply / Q000473:pathology*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D014657:Vasculitis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D003520:Cyclophosphamide; D011241:Prednisone