title: Novel chromones from Spathelia sorbifolia.
abstract: Three new chromones, namely 10-(2',3'-dihydroxy-3'-methylbutanyl)-spatheliachromen, 10-(1',2',3'-trihydroxy-3'-methylbutanyl)spatheliachromen, and 6-(3'-hydroxy-3'-methyl-trans-but-1'-enyl)-O-methylisospatheliachrome n were isolated from the 10% aqueous MeOH extract of the twigs and leaves of Spathelia sorbifolia, together with five known chromones. Compound 2, the known spatheliabischromen, and 5-O-methylsorbifolin showed cytotoxicity against 9PS cells in culture.
mesh_terms: D000107:Acetylation; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D002867:Chromones / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000032:analysis*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D002867:Chromones