Tactile-visual acquisition and reversal learning deficits in rats with prefrontal cortical lesions.
Rats with prefrontal cortex (PFC) lesions or sham operations were tested for acquisition and reversal learning with tactile-visual stimuli. PFC rats performed extremely poorly during acquisition and also differed from control rats in reversal learning. Both higher-order processing and subtle motoric dysfunctions may have combined to account for the marked effects of these cortex lesions.
D000818:Animals; D004193:Discrimination Learning / Q000502:physiology; D005625:Frontal Lobe / Q000502:physiology*; D008297:Male; D051381:Rats; D012193:Reversal Learning / Q000502:physiology*; D014110:Touch / Q000502:physiology; D014796:Visual Perception / Q000502:physiology