title: Incidence and mechanism of neutropenia and thrombocytopenia in patients with human immunodeficiency virus infection.
abstract: The incidence of lymphopenia, thrombocytopenia and neutropenia was studied in 105 homosexual men with HIV infection. Lymphopenia was common in patients with AIDS (75%), but its incidence in PGL (24%) was not significantly different from that in asymptomatic anti-HIV positive (15%) homosexual men. Neutropenia and thrombocytopenia were found in patients with AIDS or PGL, but not in asymptomatic anti-HIV positive homosexuals. The study suggests that the neutropenia and thrombocytopenia in these patients were due to autoimmune destruction of neutrophils and platelets.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000380:Agranulocytosis / Q000209:etiology*; D006716:Homosexuality; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications; D008231:Lymphopenia / Q000209:etiology; D008297:Male; D009503:Neutropenia / Q000209:etiology*; D013921:Thrombocytopenia / Q000209:etiology*