Treatment of strongyloides stercoralis with albendazole. A cure rate of 86 per cent.
A clinical trial concerning the efficacy of albendazole has been performed in an area outside the endemic zone. Sixty-eight patients were treated with albendazole in doses varying from 4-30 mg/kg/day for 3-6 days. A high cure rate of 86 per cent was obtained with albendazole 16 mg/kg/day for three days and repeated once after a fortnight. The albendazole was well tolerated and no side effects were imputed to the treatment. Successful treatment was confirmed by seven negative, consecutive coprocultures. The follow up period ranged from 35 to 615 days.
D000293:Adolescent; D000328:Adult; D000368:Aged; D015766:Albendazole; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013322:Strongyloidiasis / Q000188:drug therapy*
D000871:Anthelmintics; D001562:Benzimidazoles; D015766:Albendazole