title: [Basophilic line of the articular cartilage in normal and various pathological states].
abstract: Epiphyses of long tubular bones in the man and animals of various age, as well as experimental material of the adjuvant arthritis, with special reference to the basal part of the articular cartilage have been studied by means of histological, histochemical and histometrical methods. The structural-chemical organization of the basophilic line (tidemark) of the articular cartilage ensures its barrier role and participation in regulating selective permeability. Reconstruction of the tidemark in the process of physiological ageing and in cases of the articular pathology is aimed to preserve its integrity and in this way a complete differentiation of the noncalcified and calcified structures is secured. Disturbance of the basophilic line results in changes of the articular selective permeability, in invasion of vessels and structural elements of the bone marrow, and in development of profound distrophic and destructive changes of the cartilage--in deforming artrosis. Deflations in the structural-chemical organization of the tidemark indicate certain disturbances in the state of the system articular cartilage--subchondral bone. These data can be of prognostic importance.
mesh_terms: D000818:Animals; D001169:Arthritis, Experimental / Q000473:pathology; D001172:Arthritis, Rheumatoid / Q000473:pathology; D002113:Calcification, Physiologic; D002358:Cartilage, Articular / Q000033:anatomy & histology* / Q000378:metabolism / Q000473:pathology; D006025:Glycosaminoglycans / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D011817:Rabbits; D051381:Rats
chemical_list: D006025:Glycosaminoglycans
vernacular_title: Bazofil'naia liniia sustavnogo khriashcha v norme i pri nekotorykh patologicheskikh sostoianiiakh.