[Changes in efferent activity in the renal nerve and autonomic responses to GABA injections into structures of the ventrolateral surface of the medulla oblongata of the cat].
Acute experiments in cats revealed GABA-sensitive neurons in the chemosensitive area of the bulbar ventrolateral surface. Microinjections of GABA (1 X 10(-5)-5 X 10(-4) mol/l) into these bulbar structures produced consistent inhibition of efferent activity in renal nerves involved in maintenance of the arterial pressure level, heart rate and vascular tonus due to GABA interaction with bicuculline-sensitive GABA receptors of the neurons in this area.
D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects*; D001794:Blood Pressure; D001931:Brain Mapping; D002319:Cardiovascular System / Q000293:injuries*; D002415:Cats; D006339:Heart Rate; D007668:Kidney / Q000294:innervation*; D008526:Medulla Oblongata / Q000187:drug effects*; D008845:Microinjections; D012018:Reflex / Q000187:drug effects; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D005680:gamma-Aminobutyric Acid
Izmeneniia éfferentnoĭ aktivnosti v pochechnom nerve i vegetativnye reaktsii na vvedenie GAMK v struktury ventrolateral'noĭ poverkhnosti prodolgovatogo mozga koshki.