title: [Clinical aspects and therapy of sudden deafness. Data of a patient sample of the ear, nose, throat clinic of the Wiesbaden City Clinic 1974-1982].
abstract: 1974 to 1982 202 hospitalized patients, aged 17 to 87 years, suffering from a sudden hearing loss at first were treated between 3 and 26 days (average period 13 days) with 400 mg naftidrofuryl in low molecular weight dextrans, physiologic saline solution, glucose or leavulose solutions daily. After leaving hospital the patients received 2 dragees at 100 mg naftidrofuryl thrice a day. Provided that treatment starts within four days after the occurrence the average hearing loss measured by pure-tone audiometry was 49.2 dB before and 28.9 dB after treatment. After later beginning of therapy the values amounted to 50.8 and 35.5 dB respectively. 19 patients showed a complete remission and 77% of the patients an average hearing improvement of at least 10 dB over the measured frequencies.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold / Q000187:drug effects; D003131:Combined Modality Therapy; D005260:Female; D005663:Furans / Q000627:therapeutic use*; D003639:Hearing Loss, Sudden / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009257:Nafronyl / Q000627:therapeutic use*
chemical_list: D005663:Furans; D009257:Nafronyl
vernacular_title: Klinik und Therapie des Hörsturzes. Nach dem Patientengut der Hals-, Nasen-, Ohrenklinik der Städtischen Kliniken Wiesbaden aus den Jahren 1974 bis 1982.