title: Poor age-corrected survival of chronic lymphocytic leukaemia patients with trisomy 12.
abstract: Analyses on the prognostic impact of cellular markers in chronic lymphocytic leukaemia is hampered by the strong influence of age on survival. We have therefore used a ratio between the observed survival (or observation time) and the expected survival of age- and sex-matched healthy Swedes to eliminate the age dependence. Log rank analysis of the observed/expected survival time ratio demonstrated that CLL-patients with trisomy 12 had a poorer age-corrected survival than other patients.
mesh_terms: D000367:Age Factors; D002881:Chromosomes, Human, Pair 12; D005260:Female; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics / Q000401:mortality*; D008297:Male; D011379:Prognosis; D014314:Trisomy