Comparison of mammary adipose fatty acid composition in Japanese and American breast cancer patients.
In a comparative study of the fatty acid composition of pre- and postmenopausal Japanese and Caucasian breast cancer patients, a higher concentration of linoleic acid, the obligate precursor of arachidonic acid and its metabolites including prostaglandins, was significantly higher in postmenopausal Caucasian vs. Japanese patients. Comparable levels of linoleic acid occurred in premenopausal patients. Results indicate that a difference in linoleic acid metabolism occurs in postmenopausal Caucasian but not Japanese patients and suggest dietary modification could be beneficial in this high risk group.
D000273:Adipose Tissue / Q000032:analysis*; D001940:Breast / Q000032:analysis*; D001943:Breast Neoplasms / Q000032:analysis*; D005227:Fatty Acids / Q000032:analysis*; D005260:Female; D006801:Humans; D007564:Japan; D008593:Menopause; D014481:United States
D005227:Fatty Acids