title: Hyperprolactinemia, intrasellar pituitary tissue pressure, and the pituitary stalk compression syndrome.
abstract: The intrasellar pressure has been studied in a consecutive series of 24 patients undergoing transsphenoidal surgery for pituitary adenoma. The mean intrasellar pressure for the group was 23 +/- 2.5 mm Hg (+/- standard error of the mean), with a mean pulse pressure of 3.5 +/- 1 mm Hg. The waveform partly resembled the arterial configuration. The results are correlated with the radiological and endocrinological features of the tumors. A hypothesis is proposed to explain the mechanism of hyperprolactinemia associated with the pituitary stalk compression syndrome.
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000097:blood / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010900:Pituitary Diseases / Q000150:complications* / Q000503:physiopathology; D010911:Pituitary Neoplasms / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D011312:Pressure; D011388:Prolactin / Q000097:blood; D012658:Sella Turcica / Q000503:physiopathology*; D013577:Syndrome; D014636:Valsalva Maneuver
chemical_list: D011388:Prolactin