Positive minor cross-reaction due to red blood cell T-activation in a neonate with perforated colon.
We report the case of a prematurely born, 39-day-old male infant with a history of mechanical ileus and perforated colon in which blood grouping showed group 0 Rh (D)-positive without particularities. Minor tests, however, were distinctly positive in 4 units of blood, whereas all major tests were negative. There is strong evidence that the positive minor cross-reaction was caused by in vivo RBC T-activation with subsequent donor serum anti-T agglutination.
D015295:Antigens, Tumor-Associated, Carbohydrate; D001787:Blood Group Incompatibility / Q000097:blood*; D001788:Blood Grouping and Crossmatching; D003108:Colonic Diseases / Q000097:blood* / Q000601:surgery; D003429:Cross Reactions; D004187:Disaccharides / Q000032:analysis*; D004910:Erythrocyte Membrane / Q000378:metabolism; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood*; D007415:Intestinal Obstruction / Q000097:blood* / Q000601:surgery; D007416:Intestinal Perforation / Q000097:blood* / Q000601:surgery; D008297:Male
D015295:Antigens, Tumor-Associated, Carbohydrate; D004187:Disaccharides; C016467:Thomsen-Friedenreich antigen