title: Cyanoacrylate-fixed silicone sleds in the orbit. An animal model.
abstract: Subperiosteal wedge-shaped sleds of various materials have been used in treating the enophthalmic anophthalmic socket and in correcting the enophthalmic seeing eye. Posterior fixation of the sled may be difficult, as the sled tends to migrate anteriorly. Tissue adhesives were studied as a fixation method for silicone sleds in rabbit orbits. Gross examination revealed that the sleds were secured in position until well encapsulated. Butyl 2-cyanoacrylate (Histoacryl Blue) induced minimal inflammation, while ethyl cyanoacrylate (Crazy Glue) caused a giant-cell response.
mesh_terms: D000818:Animals; D003487:Cyanoacrylates / Q000009:adverse effects / Q000627:therapeutic use*; D007249:Inflammation / Q000209:etiology / Q000473:pathology; D009915:Orbit / Q000601:surgery*; D009916:Orbital Diseases / Q000209:etiology / Q000473:pathology; D019736:Prostheses and Implants; D011817:Rabbits; D012826:Silicone Elastomers / Q000627:therapeutic use*
chemical_list: D003487:Cyanoacrylates; D012826:Silicone Elastomers