Ciliary beat frequency and mucociliary clearance. What is the relationship?
Ciliary beat frequency (CBF), measured in vitro, and tracheal mean clearance rate (TMCR), measured in vivo, were studied in 20 nonatopic nonsmokers. CBF, measured by direct examination of nasal cells obtained by a fiberbronchoscopic brush, was 12.1 +/- 1.7 Hz (mean +/- SD). TMCR, assayed by a radioisotope technique, revealed values of 4.3 +/- 1.1 mm/min (mean +/- SD). Both of these values agree with results published by other workers. We attempted to correlate intersubject variation in TMCR with variation in CBF but found no direct relationship, findings similar to those reported in studies done on frog palate epithelium.
D000328:Adult; D001692:Biological Transport; D001999:Bronchoscopy; D002923:Cilia / Q000502:physiology; D005260:Female; D005336:Fiber Optic Technology / Q000295:instrumentation; D006801:Humans; D008297:Male; D009093:Mucus / Q000502:physiology*; D009297:Nasal Mucosa / Q000502:physiology*; D013668:Technetium Tc 99m Aggregated Albumin; D014132:Trachea / Q000502:physiology*
D013668:Technetium Tc 99m Aggregated Albumin