Antagonism between selenium and humic acid.
In this work, two groups of experiments have been done by using mice and luminous bacteria. The results show that there exists an antagonism in toxicity between selenium and humic acid (HA) extracted from the drinking water in Kaschin Beck disease regions. In order to study the chemical mechanism of the antagonism, gel filtration and X-ray photoelectron spectroscopy techniques have been used to study the chemical bonding of the synthetic HA-Se in solution. The relationship between Se and HA in the cause of Kaschin Beck disease is discussed.
D000818:Animals; D001578:Benzopyrans / Q000037:antagonists & inhibitors*; D005260:Female; D051379:Mice; D010003:Osteoarthritis / Q000209:etiology; D010776:Photobacterium / Q000187:drug effects; D051381:Rats; D012643:Selenium / Q000494:pharmacology*; D018036:Selenium Compounds; D064588:Selenium Oxides; D014881:Water Supply / Q000032:analysis
D001578:Benzopyrans; D018036:Selenium Compounds; D064588:Selenium Oxides; D012643:Selenium; C005023:fulvic acid