Quantitative confirmation of dimetridazole and ipronidazole in swine feed by capillary gas chromatography/mass spectrometry with multiple ion detection.
Extracts from 4 types of swine feed containing 0.11 ppm each of dimetridazole (DMZ) and ipronidazole (IPR) were analyzed by capillary gas chromatography/mass spectrometry (GC/MS) using multiple ion detection (MID) techniques. We demonstrate in this paper that the quantitative results obtained by capillary GC/MS with MID are comparable for both compounds to results obtained by liquid chromatography and have a lower coefficient of variation for DMZ. Moreover, consistency in the ion ratios (5 ions in DMZ and 6 ions in IPR) permits identification of these compounds by electron ionization MS.
D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D004131:Dimetridazole / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D007491:Ipronidazole / Q000032:analysis*; D009593:Nitroimidazoles / Q000032:analysis*; D013552:Swine
D009593:Nitroimidazoles; D007491:Ipronidazole; D004131:Dimetridazole