Mechanical bowel preparation for colonic resection and anastomosis.
In a series of 72 consecutive elective and emergency colectomies with primary anastomosis, all pre- and perioperative mechanical preparation of the bowel was omitted and the patient covered only by a single peroperative intravenous dose of cefuroxime and metronidazole. No anastomotic dehiscence was clinically apparent and wound infection was noted in only 8.3 per cent of patients.
D000328:Adult; D000368:Aged; D002444:Cefuroxime / Q000008:administration & dosage; D003082:Colectomy / Q000009:adverse effects / Q000379:methods; D003106:Colon / Q000601:surgery*; D003108:Colonic Diseases / Q000601:surgery; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage; D008875:Middle Aged; D011300:Preoperative Care; D012007:Rectum / Q000601:surgery*; D013530:Surgical Wound Infection / Q000209:etiology / Q000517:prevention & control
D008795:Metronidazole; D002444:Cefuroxime