[Changes in the phospholipid composition of liver mitochondrial membranes in rats treated with ethanol].
Phospholipid composition was studied in liver mitochondrial membranes of rats consuming ethanol for a long time. A new phospholipid phosphatidyl ethanol was found in the membranes, which appears to be formed due to the action of endogenous phospholipase D. The phospholipase D activity was measured in mitochondria using direct evaluation. Administration of ethanol led to alteration in the ratio of mitochondrial phospholipids.
D000818:Animals; D000431:Ethanol / Q000633:toxicity*; D007425:Intracellular Membranes / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats
D008563:Membrane Lipids; D010743:Phospholipids; D000431:Ethanol
Izmenenie fosfolipidnogo sostava membran mitokhondriĭ pecheni krys pri vvedenii im étanola.