title: [Microangiopathic hemolytic anemia, erythrophagocytosis and consumption coagulopathy in vinyl chloride-induced hemangiosarcoma of the spleen and liver].
abstract: A case of angiosarcoma of the liver and the spleen following vinyl chloride exposure is described. The main symptoms in clinical diagnosis were microangiopathic hemolysis, disseminated intravascular coagulation, hepatosplenomegaly and exposure to vinyl chloride thirty years ago. It is the first case in which liver and spleen are involved in angiosarcoma due to vinyl chloride exposure. The tumor cells showed angioformative and solid histiocytoid growth with erythrophagocytosis.
mesh_terms: D000368:Aged; D000743:Anemia, Hemolytic / Q000139:chemically induced*; D004211:Disseminated Intravascular Coagulation / Q000139:chemically induced*; D004781:Environmental Exposure; D004912:Erythrocytes; D005260:Female; D006394:Hemangiosarcoma / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D010587:Phagocytosis; D014752:Vinyl Chloride / Q000009:adverse effects*; D014753:Vinyl Compounds / Q000009:adverse effects*
chemical_list: D014753:Vinyl Compounds; D014752:Vinyl Chloride
vernacular_title: Mikroangiopathische hämolytische Anämie, Erythrophagozytose und Verbrauchskoagulopathie bei vinylchloridinduziertem Hämangiosarkom von Milz und Leber.