Genetically determined resistance to 3-methylcholanthrene-induced lymphoma is expressed at the level of bone marrow-derived cells.
Reciprocal bone marrow transfers were performed between mouse strains sensitive or resistant to 3-methylcholanthrene-induced thymic lymphoma. Sensitivity and resistance are properties inherent in bone marrow, and cannot be altered by maturation of marrow in an environment of the opposite phenotype.
D000818:Animals; D001854:Bone Marrow Cells; D002678:Chimera; D004351:Drug Resistance; D008223:Lymphoma / Q000139:chemically induced / Q000235:genetics*; D008748:Methylcholanthrene; D051379:Mice; D008815:Mice, Inbred Strains; D010641:Phenotype
D008748:Methylcholanthrene