title: A microcomputer-based distributed data management system for a large cooperative study of transfusion associated acquired immunodeficiency syndrome.
abstract: This paper describes the details of a microcomputer-based, distributed data management system in the acquisition of data collected in a large multicentered cooperative investigation of transfusion-transmitted acquired immunodeficiency syndrome (AIDS). Clinical, virological, and immunological data are obtained from six clinical centers and six central laboratories using a variety of hardware components and software packages. Data are merged and processed on a mainframe computer at the Biostatistics Office at the University of Southern California. The advantages and disadvantages of this system are discussed relative to the dynamics of the study, the magnitude and nature of the database, and the organization of the distributed centers involved.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000209:etiology*; D003195:Computer Communication Networks; D003199:Computer Systems; D003201:Computers; D003628:Database Management Systems; D006801:Humans; D007121:Immunocompetence; D007256:Information Systems / Q000458:organization & administration*; D008838:Microcomputers; D012984:Software; D065227:Transfusion Reaction; D014481:United States