Gastrin/CCK-like immunoreactivity in the corpus cardiacum-corpus allatum complex of the cockroach Leucophaea maderae.
By use of immunocytochemistry, a gastrin/CCK-like material has been demonstrated in the corpus cardiacum-corpus allatum complex of the cockroach Leucophaea maderae. Reactivity toward gastrin and CCK with region-specific antisera suggests that the gastrin/CCK-like peptide of this insect contains the COOH-terminal tetrapeptide sequence which is common to gastrin and CCK, and that the material is more gastrin-like than CCK-like. The results indicate that, like other neuropeptides, the gastrin/CCK peptide family appeared early in evolution within neuronal elements, and that the COOH-terminal region of gastrin has been conserved during phylogeny.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000032:analysis; D002766:Cholecystokinin / Q000032:analysis*; D003058:Cockroaches / Q000166:cytology*; D005755:Gastrins / Q000032:analysis*; D007106:Immune Sera; D014018:Tissue Distribution
D000936:Antigen-Antibody Complex; D005755:Gastrins; D007106:Immune Sera; D002766:Cholecystokinin