[Parasympathetic regulation of cardiac rhythm in delta sleep-inducing peptide deficiency].
The effect of delta-sleep peptide (DSP) deficiency on the parasympathetic regulation of the heart rate was studied on 35 rabbits. It was established that the injection of an-serum (titer-1:2000-1:3000) leads to the attenuation of parasympathetic influences: heart rate increase in freely behaving animals and a decrease in negative chronotropic effect with direct vagus irritation. Antiserum, like DSP, administration causes practically no damage of the myocardial ultrastructure.
D000818:Animals; D003701:Delta Sleep-Inducing Peptide / Q000172:deficiency* / Q000276:immunology; D004558:Electric Stimulation; D006339:Heart Rate / Q000187:drug effects; D007106:Immune Sera / Q000494:pharmacology; D007114:Immunization; D009206:Myocardium / Q000648:ultrastructure; D010275:Parasympathetic Nervous System / Q000187:drug effects / Q000502:physiology*; D011817:Rabbits; D014630:Vagus Nerve / Q000502:physiology
D007106:Immune Sera; D003701:Delta Sleep-Inducing Peptide
Parasimpaticheskaia reguliatsiia serdechnogo ritma v usloviiakh defitsita peptida del'ta-sna v organizme.