[Effect of vasoactive substances on the microhemodynamics and filtration-absorption function of the lungs].
Influence of noradrenaline and serotonin induced a drop in postcapillary resistance, capillary hydrostatic pressure and the capillary filtration coefficient whereas precapillary regional vascular resistance and the pre- to postcapillary resistance ratio increased. Histamine increased integral, postcapillary resistance and capillary hydrostatic pressure. Acetylcholine decreased pre and postcapillary resistance as well as the integral vascular one, the capillary filtration coefficient increasing, at that. Possible mechanisms of the effects of the drugs under study are discussed.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001679:Biogenic Amines / Q000494:pharmacology*; D002199:Capillary Permeability / Q000187:drug effects; D002415:Cats; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006632:Histamine / Q000494:pharmacology; D006874:Hydrostatic Pressure; D008168:Lung / Q000098:blood supply*; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology; D014655:Vascular Resistance / Q000187:drug effects
D001679:Biogenic Amines; D012701:Serotonin; D006632:Histamine; D000109:Acetylcholine; D009638:Norepinephrine
Vliianie vazoaktivnykh veshchestv na mikrogemodinamiku i fil'tratsionno-absorbtsionnuiu funktsiiu legkikh.