title: [Studies on the interrelation of fetal heart rate change, placental findings and fetal outcome].
abstract: The relation between antepartum fetal heart rate (FHR) non stress test (NST), maternal serum estriol, intrapartum FHR change, birth weight, placental findings and Apgar score were studied in 168 normal gestations and 36 high-risk pregnancies including 25 EPH-gestosis cases. The frequency of placental infarcts was higher in severe gestosis than in other high-risk pregnancies and normal gestation. Abnormal NST was more frequent in high-risk pregnancy than normal. Light for date (LFD) infants were more numerous in high-risk pregnancy than normal, and also frequent in the cases of placental infarcts. Particularly in high-risk pregnancy patients with abnormal NST and placental infarcts, 3 out of 5 showed LFD infants. Intrapartum fetal distress was more common in the cases of abnormal NST than normal. The five minute Apgar score was lower in the patients with abnormal NST and in the cases of placental infarcts than normal. The placental infarct ratio was higher in high-risk pregnancies with abnormal NST than normal. The maternal serum estriol level was not changed in cases of high-risk pregnancy, abnormal NST or placental infarcts when compared to normal gestation. The cases of succeeding fetal death, however, showed a low serum estriol level. In conclusion, antepartum abnormal NST suggests severe placental dysfunction caused by its infarcts and the prognosis is poor in patients with high-risk pregnancies, particularly EPH-gestosis. Coping with abnormal antepartum NST is regarded as important in fetal management.
mesh_terms: D001034:Apgar Score; D001724:Birth Weight; D004964:Estriol / Q000097:blood; D005260:Female; D005313:Fetal Death / Q000097:blood; D005315:Fetal Diseases / Q000503:physiopathology*; D006340:Heart Rate, Fetal; D006801:Humans; D007231:Infant, Newborn; D007238:Infarction / Q000503:physiopathology*; D009929:Organ Size; D010920:Placenta / Q000033:anatomy & histology / Q000098:blood supply*; D011225:Pre-Eclampsia / Q000503:physiopathology; D011247:Pregnancy; D011379:Prognosis
chemical_list: D004964:Estriol