title: A regression analysis program to fit nonseparable equations.
abstract: A program to perform a nonlinear best fit for separable and nonseparable equations is described. This software is written in Turbo-Pascal so that it can be run both on CP/M systems or PC-DOS systems; in the latter, graphics can be performed using the Turbo Graphix Toolbox. From initial estimates the regression coefficients as well as the statistics are calculated. Two examples are shown: one of a separable equation describing receptor binding; the second of a nonseparable equation, describing the displacement of labeled agonist by an inhibitor. The only difference in the fit between a separable and a nonseparable equation is that the latter requires iterations for an estimate of the dependent variable every time that new regression coefficients are calculated.
mesh_terms: D008838:Microcomputers; D011955:Receptors, Drug / Q000378:metabolism; D012044:Regression Analysis; D012984:Software
chemical_list: D011955:Receptors, Drug