title: [Analysis of multiple primary malignant tumors including lung cancer].
abstract: In our hospital, from 1984 to 1986, we have performed autopsies on 50 lung cancer cases. Ten (20%) cases were found to have multiple primary malignant tumors, ie. one quadruple, 2 triple, 7 double malignant tumors, and almost all cases with multiple primary malignancies were males more than 70 years old. A histological examination showed that seven of these had tumors of the squamous cell type. In six cases, lung cancer was the primary disease and in 5 cases both malignancies existed simultaneously. When we lysed 5 g of autopsied lung, we were able to detect more than 100 asbestos bodies in 9 cases out of ten. Further, we noticed that triple or quadruple cases showed more asbestos bodies. Thus, we suspect that nearly all cases had been affected by exposure to asbestos.
mesh_terms: D000368:Aged; D001195:Asbestosis / Q000150:complications; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000453:epidemiology; D007564:Japan; D008175:Lung Neoplasms / Q000453:epidemiology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology*; D011471:Prostatic Neoplasms / Q000453:epidemiology; D013274:Stomach Neoplasms / Q000453:epidemiology