title: Anterior segment autonomic dysfunction in ocular hypertension.
abstract: Autonomic nerve function in the anterior segment of the eye was assessed by measurement of the pupil cycle time in 189 patients with ocular hypertension and 70 age- and sex-matched control subjects. Parasympathetic dysfunction was significantly present in ocular hypertensive patients with narrow irido-corneal angles, though not in wide-angle subjects. The results are discussed, with particular reference to the accumulating evidence implicating autonomic dysfunction as a significant factor in the pathogenesis of the primary glaucomas.
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000294:innervation*; D001342:Autonomic Nervous System Diseases / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D008962:Models, Theoretical; D009798:Ocular Hypertension / Q000150:complications* / Q000503:physiopathology; D011680:Pupil; D013997:Time Factors