Chronic atrophic rhinitis with fetor (ozena): a histopathologic tretise.
Biopsy material from 50 patients with a known clinical diagnosis of ozena was examined histopathologically. Certain features were invariably seen, including mucosal atrophy, squamous metaplasia, and chronic inflammatory cell infiltrate which suggests a humoral mediated immune process. Histopathologic features allow ozena to be distinguished from chronic non-specific hypertrophic rhinitis, which may have a cell-mediated immune basis underlying its pathogenesis.
D000293:Adolescent; D000328:Adult; D001485:Basement Membrane / Q000473:pathology; D001706:Biopsy; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008679:Metaplasia; D009297:Nasal Mucosa / Q000473:pathology; D012222:Rhinitis, Atrophic / Q000473:pathology*