title: Prepartum supplementation of selenium and vitamin E to dairy cows: assessment of selenium status and reproductive performance.
abstract: Incidence of retained placenta in dairy cows was evaluated in 627 parturitions. The herd was divided prepartum into three groups: 1) control, no treatment (n = 217 cows); 2) cows injected intramuscularly (n = 190) 21 to 10 d prior parturition with 45 mg Se and 2040 IU of vitamin E; and 3) cows intraruminally administered (n = 220) with two 30-g pellets containing 10% elemental selenium 2 mo prior to expected calving. Incidence of retained placenta (22.1%) was not reduced by Se in combination with vitamin E injection or intraruminal Se pellet nor were other measures of reproduction improved for cows fed a prepartum diet adequate in Se. At parturition the blood plasma Se concentrations were higher in treated postpartum with Se than in untreated cows. No difference in blood plasma Se was observed at parturition between cows with or without placenta retention. Cows dosed intraruminally with Se had a significant increase in milk Se, but this was too small to be a danger to human health. The present results on placenta retention suggest that this disorder is not a Se responsive disease in the dairy cow.
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D005260:Female; D008892:Milk / Q000032:analysis; D010922:Placenta Diseases / Q000517:prevention & control / Q000662:veterinary*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D012643:Selenium / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D014810:Vitamin E / Q000494:pharmacology*
chemical_list: D014810:Vitamin E; D012643:Selenium