[Expression of blood group antigens in 30 patients with transitional-cell carcinomas of the bladder].
From the follow up of 30 patients whose bladder tumours were repeatedly resected over a period ranging from several months to 18 years, we carried out a study of AGS Antigen expression using an A B O histokit. We were able to establish that this histokit is reliable and very easy to use. We also observed in the urothelial tumours a modification in AGS expression tending towards frequent loss. The AGS staining coincides with the grade of the tumour. Tumours totally stained are always of low grade. However, in this short group of patients, we were unable to draw any interesting correlation between the immunological profile and the clinical course of the transitional bladder carcinomas. In the case of patients with superficial tumours whose histological aspect and clinical course are comparable, the immunological aspect differs. It must be emphasised that in subsequent studies necessary to establish the prognosis of bladder tumours the A B O histokit is easy to use in conjunction with the histological study.
D000017:ABO Blood-Group System / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology*; D002295:Carcinoma, Transitional Cell / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis; D011933:Reagent Kits, Diagnostic; D001749:Urinary Bladder Neoplasms / Q000276:immunology* / Q000473:pathology
D000017:ABO Blood-Group System; D000951:Antigens, Neoplasm; D011933:Reagent Kits, Diagnostic
Etude de l'expression des antigènes de groupe sanguin chez 30 malades porteurs de carcinomes transitionnels de vessie.