title: [Therapy of the anticholinergic syndrome in poisonings].
abstract: Underlying literature and taking into consideration own experiences in the anticholinergic syndrome the following view is taken: Physostigmine salicylate is the remedy of choice for the treatment of the anticholinergic syndrome and altogether causes only slight side effects. While for differential-diagnostic reasons the application is recommended under hospital conditions, the pre-hospital application is to be estimated as problematical. The improvement of the clinical symptoms under the influence of physostigmine salicylate must not lead to the neglect of the control of the patient. A differentiated use of physostigmine salicylate is necessary, and it cannot be regarded as "universal antidote" in intoxications caused by central-nervous effective substances.
mesh_terms: D000293:Adolescent; D002799:Cholinergic Fibers / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D009567:Nitrazepam / Q000506:poisoning; D010640:Phenothiazines / Q000506:poisoning; D010830:Physostigmine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011041:Poisoning / Q000188:drug therapy*; D013577:Syndrome
chemical_list: D010640:Phenothiazines; C026718:physostigmine salicylate; D009567:Nitrazepam; D010830:Physostigmine; C031637:phenothiazine
vernacular_title: Die Therapie des anticholinergen Syndroms bei Intoxikationen.