Anticonvulsant drugs, growth, and development.
Height and stage of puberty of 67 children with epilepsy were measured before beginning treatment with anticonvulsant drugs and annually to a maximum five years' treatment. Blood concentrations of the drugs used (phenytoin, sodium valproate, carbamazepine, ethosuximide, and phenobarbitone) were monitored throughout. No significant deviation in growth patterns was detected.
D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D001827:Body Height / Q000187:drug effects*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012741:Sexual Maturation / Q000187:drug effects*
D000927:Anticonvulsants