Inference for an age-dependent, multitype branching-process model of mast cells.
We consider an age-dependent, multitype model for the growth of mast cells in culture. After a colony of cells is established by an initiator type, the two possible types of cells are resting and proliferative. Using novel inferential procedures, we estimate the generation-time distribution and the offspring distribution of proliferative cells, and the waiting-time distribution of resting cells.
D000818:Animals; D002455:Cell Division; D002470:Cell Survival; D002478:Cells, Cultured; D007700:Kinetics; D008407:Mast Cells / Q000166:cytology*; D008433:Mathematics; D051379:Mice; D008954:Models, Biological