title: [Reproduction and differentiation of cells in the tissues of growing rat teeth in response to parathyroid hormone and hydrocortisone].
abstract: Influence of parathyroid hormone (PTH) and hydrocortisone (HC) on growth and development of teeth during prefunctional period has been studied, employing radioactive tracers. Biosynthetic and reproductive activity of cells is estimated in the molar and incisor tissues. It has been established that PTH accelerates the process of local resorption of the bone along the alveolar crest, but does not influence upon the teeth growth, functional and reproductive activity of the pulp cells. HC inhibits protein and glycoprotein synthesis, decreases amount of proliferating cells, accelerates their differentiation and, thus, delays formation of the root and tooth growth.
mesh_terms: D000565:Ameloblasts / Q000187:drug effects; D000818:Animals; D001862:Bone Resorption / Q000187:drug effects; D002454:Cell Differentiation; D006854:Hydrocortisone / Q000494:pharmacology*; D008938:Mitosis / Q000187:drug effects; D009804:Odontoblasts / Q000187:drug effects; D009805:Odontogenesis / Q000187:drug effects*; D010281:Parathyroid Hormone / Q000494:pharmacology*; D014176:Protein Biosynthesis; D051381:Rats; D011919:Rats, Inbred Strains; D014078:Tooth Eruption / Q000187:drug effects
chemical_list: D010281:Parathyroid Hormone; D006854:Hydrocortisone
vernacular_title: Reproduktsiia i differentsirovka kletok v tkaniakh rastushchikh zubov krysy pri deĭstvii paratireoidnogo gormona i gidrokortizona.