title: [Treatment of duodenal ulcer with the Bulgarian preparation gastralgin].
abstract: The effect of the new Bulgarian preparation gastralgin was studied in 20 patients with duodenal ulcer. The preparation was given three times daily in the course of 20 days--I bag, 1/2 to 1 hour before meals and in the evening before going to bed. Gastralgin contains in one bag--alginic acid 0.500, sodium alginate 0.500, aluminium hydroxide 0.200, magnesium hydroxide 0.100, calcium carbonate 0.500 and corrigent up to 7g. Favourable effect on the separate symptoms was attained in 50 to 80% after the treatment, epithelialization of the ulcer in 40% and reduction of its size in 25%. No change in gastric secretion was observed. Gastralgin, with its therapeutic effect, is equivalent to the preparations almagel and flatugel and their improved variants. The preparation is well tolerated and gives no adverse effects, hence it is recommended for the treatment of duodenal ulcer.
mesh_terms: D000328:Adult; D000863:Antacids / Q000627:therapeutic use*; D004341:Drug Evaluation; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008297:Male; D013997:Time Factors
chemical_list: D000863:Antacids
vernacular_title: Lechenie na duodenalnata iazva s bŭlgarskiia preparat gastralgin.