[Effect of thiamine and its derivatives on acetylcholinesterase activity of the blood and brain of albino mice].
Thiamine, thiaminepyrophosphate and 4-methyl-5-beta-oxyethylthiazole are studied for their effect on the acetylcholinesterase activity in the brain, blood plasma and cells. The activity of acetylcholinesterase in blood cells is shown to be inhibited most of all by thiamine and thiazole. Acetylcholinesterase of the brain has been efficiently inhibited only by thiamine pyrophosphate.
D000110:Acetylcholinesterase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000201:enzymology*; D002800:Cholinesterase Inhibitors; D004912:Erythrocytes / Q000201:enzymology; D051379:Mice; D013831:Thiamine / Q000494:pharmacology*; D013835:Thiamine Pyrophosphate / Q000494:pharmacology; D013844:Thiazoles / Q000494:pharmacology
D002800:Cholinesterase Inhibitors; D013844:Thiazoles; C012572:2-(4-methyl-1,3-thiazol-5-yl)ethanol; D000110:Acetylcholinesterase; D013835:Thiamine Pyrophosphate; D013831:Thiamine
Vliianie tiamina i ego proizvodnykh na aktivnost' atsetilkholinésterazy mozga i krovi belykh mysheĭ.