[Peri-implant enzyme activities and mineralization in bone tissue after implantation of bioactive vitroceramics--a method for biomaterial testing of hard-tissue substitutes. 1. Establishment and representation of the method].
A method for testing the bioactivity of hard tissue implants is described by analysis of the periimplantary enzyme activities of the alkaline and the acid phosphatase in the femur of rats. Bioactive materials cause an increase of the activity of the alkaline phosphatase in the periimplantal bone tissue. An increase of the activity of the acid phosphatase is a measure for the biodepressive effect of the implant material.
D000135:Acid Phosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration; D001842:Bone and Bones / Q000201:enzymology*; D002516:Ceramics; D005269:Femur; D066298:In Vitro Techniques; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D001672:Biocompatible Materials; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase
Untersuchungen periimplantärer Enzymaktivitäten und der periimplantären Mineralisation im Knochengewebe nach Implantation bioktiver vitrokeramischer Materialien--Eine Methode der Biomaterialprüfung für den Hartgewebeersatz. Teil 1: Begründung und Darlegung der Methodik.