title: An evaluation of the Coulter Counter Model T660.
abstract: An evaluation of a Coulter Counter Model T660 has been carried out. This instrument is a compact, fully automated, blood cell counter which measures WBC, RBC, Hb, haematocrit, MCV and platelet count on a 100 microliter sample of whole blood. The instrument was assessed during one month of regular use. One possible microbiological hazard was detected, which could be corrected by an instrument modification. No mechanical hazards were identified. The instrument as supplied produced some inaccurate WBCs; this malfunction appeared to be consequent on a design fault relating to the burn circuit of the white cell aperture and following instrument modification performance was considerably improved. Results produced were broadly comparable with those produced by a Coulter Counter Model S Plus IV. Precision was satisfactory. Deviations from linearity on dilution were not sufficient to be of practical importance. Carryover was satisfactorily low. Time-lapse of up to 48 h did not introduce inaccuracy of sufficient magnitude to be of practical importance. Throughout varied from 52 to 63 specimens/h. Following instrument modification the overall assessment was that the T660 was easy to operate, reliable, and clinically useful.
mesh_terms: D001772:Blood Cell Count / Q000191:economics / Q000295:instrumentation*; D004906:Erythrocyte Count; D005069:Evaluation Studies as Topic; D006400:Hematocrit; D006801:Humans; D007958:Leukocyte Count; D010976:Platelet Count; D013997:Time Factors