Dapsone syndrome--a case report.
A 31-year-old male patient with lepromatous leprosy developed fever, malaise, nausea, anorexia, lymphadenopathy, hepatitis, exfoliative dermatitis and ainhum like lesions while on multidrug therapy comprised of dapsone, clofazimine and rifampicin. The provocation tests confirmed the dapsone to be cause of this event.
D000328:Adult; D002991:Clofazimine / Q000627:therapeutic use; D003622:Dapsone / Q000009:adverse effects* / Q000627:therapeutic use; D003872:Dermatitis / Q000139:chemically induced*; D004359:Drug Therapy, Combination; D006801:Humans; D007918:Leprosy / Q000188:drug therapy*; D008297:Male; D012293:Rifampin / Q000627:therapeutic use
D003622:Dapsone; D002991:Clofazimine; D012293:Rifampin