Heterogeneity of postnatal development of ACh levels in brain regions of the mouse.
Acetylcholine (ACh) was measured from birth to the 78th day in 11 mouse brain regions. Three patterns of development emerged: ACh increased rapidly, overshot and returned to the adult level in midbrain-medulla-pons and cerebellum, ACh increased linearly to adult level in neostriatum and olfactory bulb and ACh increased linearly to a plateau and then increased to the adult level in the remaining regions.
D000109:Acetylcholine / Q000032:analysis*; D000110:Acetylcholinesterase / Q000032:analysis; D000375:Aging / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000254:growth & development; D001923:Brain Chemistry; D002795:Choline O-Acetyltransferase / Q000032:analysis; D051379:Mice; D008815:Mice, Inbred Strains; D009419:Nerve Tissue Proteins / Q000032:analysis
D009419:Nerve Tissue Proteins; D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase; D000109:Acetylcholine