Estimation of segregation and ascertainment probabilities by discarding the single probands.
The first portion of this communication reiterates the method of discarding single probands for studying the segregation ratio under incomplete ascertainment. The organization of the algebra leads to the second portion, in which the "self-contained" subsets are constructed with respect to both the segregation ratio and the ascertainment ratio. These subsets make a more detailed study of segregation and ascertainment possible.
D030342:Genetic Diseases, Inborn / Q000235:genetics; D005826:Genetics, Medical; D006801:Humans; D008957:Models, Genetic; D011336:Probability