[Action of apilak on the electrolyte and catecholamine content of the wall of arterial vessels at different levels of systemic arterial pressure].
In cats with elevated systemic arterial blood pressure apilac (1 mg/kg, a single dose or course administration) significantly decreased the arterial vessel wall contents of ions of Na+, Ca2+ and catecholamines the levels of which exceeded control values. Apilac administration to animals with normal systemic arterial blood pressure resulted in a decrease of Ca2+ ion content, an increase of Na+, K+ and Mg2+ ion concentrations in the vessel wall. The content of catecholamines remained in the range of control values.
D000818:Animals; D001158:Arteries / Q000032:analysis / Q000187:drug effects*; D001516:Bees; D001688:Biological Products / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D002395:Catecholamines / Q000032:analysis*; D002415:Cats; D004573:Electrolytes / Q000032:analysis*; D005260:Female; D008297:Male; D013997:Time Factors
D001688:Biological Products; D002395:Catecholamines; D004573:Electrolytes; C032051:apilacum
Deĭstvie apilaka na soderzhanie élektrolitov i katekholaminov v stenke sosudov arterial'nogo tipa pri razlichnykh urovniakh sistemnogo arterial'nogo davleniia.