Effects of lowered pH of the extracellular solution on non-transsynaptic component of evoked potentials in the rat's in vitro cerebral cortical slices.
The effects of lowered extracellular pH on non-transsynaptic component of field potentials evoked by electric stimulation of the white matter which were recorded in layer IV of the occipital cerebral cortex were studied with the rat's in vitro brain slices. At a range of pH between 6.2 and 7.2, the amplitude of the non-transsynaptic potentials was decreased with a complete recovery to the initial normal level when the pH was restored to 7.4. With a decrease in amplitude, the latency of evoked potentials was also delayed a little in the acidic media.
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology*; D004558:Electric Stimulation; D005071:Evoked Potentials; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D051381:Rats; D013569:Synapses / Q000502:physiology