[Modifying effect of IgE hyperproduction on the proliferative response of lymphocytes from intact mice and mice with transplanted tumors].
It is shown that under conditions of IgE-induced reaction the tumour growth is altered, which may be explained by different degree of expression of functional activities of immunocompetent cells in mice with transplanted tumours and marked immediate-type reaction. Changes in the immunological state manifest in stimulation of the proliferative response primarily to B-cell mitogens under conditions of increased synthesis of IgE, which permits suggesting that under these conditions B-cells play an important role in antitumour immunity.
D000818:Animals; D005260:Female; D006942:Hypergammaglobulinemia / Q000276:immunology*; D007073:Immunoglobulin E / Q000276:immunology*; D008213:Lymphocyte Activation; D051379:Mice; D008807:Mice, Inbred BALB C; D008934:Mitogens; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology*
D008934:Mitogens; D007073:Immunoglobulin E
Modifitsiruiushchee vliianie giperproduktsii IgE na proliferativnyĭ otvet limfotsitov intaktnykh mysheĭ i mysheĭ s perevivnymi opukholiami.