title: [Evaluation of low-dose cobalt teletherapy in the treatment of oropharyngeal cancers of moderate extension].
abstract: Comparative efficacy of treatment with irradiation of 20 Gy, either conventionally fractionated (33 cases) or by semi-continuous low-dose irradiation (32 cases) was studied in 65 patients with oropharyngeal cancer with moderate extension (T2b and T3a). Survival rate was 44% in the low-dose group as against 24% in the conventionally treated group at 2-year follow up review. More particularly, however, there were 4 times fewer recurrences in the low-dose group (16% as against 61% in conventional group). This suggests the need for continuing study of the time factor in radiotherapy, although a few cases of necrosis (16%) were observed in the low-dose group.
mesh_terms: D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D006801:Humans; D009959:Oropharyngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D010610:Pharyngeal Neoplasms / Q000532:radiotherapy*; D011867:Radioisotope Teletherapy
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Bilan de la télécobalthérapie à faible débit dans le traitement des cancers oro-pharyngés moyennement étendus.