[Use of transesophageal electrostimulation of the heart for evaluating the effectiveness of anti-anginal therapy].
Investigation and treatment of 32 patients with stable angina and 17 patients with acute myocardial infarction are reported. The efficiency of antianginal treatment was assessed on the basis of clinical data as well as the results of repeated functional tests (esophageal electrostimulation of the heart) and central hemodynamic changes. It is demonstrated that the esophageal electrostimulation test can be used to assess the efficiency of antianginal medication on the basis of anginal threshold increment. A new long-acting nitrate, Isomak R (forte), has been shown to be an effective antianginal drug; it increases physical stress tolerance, prevents attacks of angina of effort or angina at rest, significantly decreases pulmonary arterial occlusion pressure, peripheral arterial pressure and total peripheral resistance. No important side effects have been recorded.
D000368:Aged; D000787:Angina Pectoris / Q000175:diagnosis / Q000188:drug therapy*; D002214:Capsules; D006328:Cardiac Catheterization; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D003692:Delayed-Action Preparations / Q000627:therapeutic use; D004341:Drug Evaluation / Q000379:methods; D004562:Electrocardiography / Q000379:methods; D004947:Esophagus; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy
D002214:Capsules; D003692:Delayed-Action Preparations; D007548:Isosorbide Dinitrate
Primenenie chrespishchevodnoĭ élektrostimuliatsii serdtsa dlia otsenki éffektivnosti antianginal'noĭ terapii.