[Induction of the monooxygenase system and the transport of xenobiotics in the kidney].
Phenobarbital (50 mg/kg) and benzonal (35 mg/kg) orally for 4 days and 3-methylcholanthrene (20 mg/kg) subcutaneously increased the excretion and tubular maximal transport of cardiotrast (diodrast) in rats. The inductors of the monooxigenase system seem to stimulate the renal transport of xenobiotics.
D000818:Animals; D001463:Barbiturates / Q000494:pharmacology*; D004790:Enzyme Induction; D007684:Kidney Tubules / Q000187:drug effects* / Q000378:metabolism; D008748:Methylcholanthrene / Q000494:pharmacology*; D010105:Oxygenases / Q000096:biosynthesis*; D010634:Phenobarbital / Q000494:pharmacology*; D051381:Rats
D001463:Barbiturates; D008748:Methylcholanthrene; D010105:Oxygenases; C002915:benzobarbital; D010634:Phenobarbital
Induktsiia monooksigenaznoĭ sistemy i transport ksenobiotikov v pochke.