[Effect of alpha-tocopherol on the physicochemical properties of liver cell membranes in adrenalectomized rats].
The increased content of lipid peroxidation products in the liver and an associated increase in the microviscosity of lipid nuclear and microsomal liver cell membranes, as well as disturbed protein-lipid interaction in them have been determined 8 days after adrenalectomy. The addition of alpha-tocopherol into the diet (4 mg per day for 7 days after the operation) prevented the activation of lipid peroxidation and the disturbances of physico-chemical membrane properties and the decrease in the muscular working capacity in rats caused by adrenalectomy.
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D008054:Lipid Peroxides / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
D008054:Lipid Peroxides; D014810:Vitamin E; D024502:alpha-Tocopherol; D024505:Tocopherols
Vliianie al'fa-tokoferola na fiziko-khimicheskie svoĭstva membran kletok pecheni adrenaléktomirovannykh krys.