title: Projection neurons of basolateral amygdaloid nuclei develop meganeurites in juvenile and adult human neuronal ceroid lipofuscinosis.
abstract: In human neuronal ceroid lipofuscinosis (NCL) meganeurite formation is seen in specific portions of the basolateral amygdaloid complex. Proceeding from the lateral nucleus via the basal nuclei to the accessory basal nucleus, pathological changes, from severe to mild, are found. The parvocellular granular nucleus and the intercalated cell masses remain unchanged. Only the projection cells of the lateral, basal, and accessory basal nucleus develop lipopigment filled meganeurites.
mesh_terms: D000328:Adult; D000679:Amygdala / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D009472:Neuronal Ceroid-Lipofuscinoses / Q000473:pathology*; D009474:Neurons / Q000473:pathology*