[Delayed-type hypersensitivity reaction induced in mice by the administration of an inactivated influenza vaccine].
The conditions of delayed-type hypersensitivity induction following immunization with an inactivated influenza vaccine in BALB/c and CBA/H mice treated with cyclophosphane were studied. The results showed that the delayed-type hypersensitivity reaction had no type specificity when revealing preparation injected to immunized mice is a vaccine prepared with chorioallantoic fluid, but it is specific when a tissue vaccine is used. The use of inactivated influenza viruses cultivated on different cell-types for sensitization and revelation of the hypersensitivity state allowed to evaluate the level of the delayed-type hypersensitivity induced by untreated virus.
D000818:Animals; D006968:Hypersensitivity, Delayed / Q000209:etiology* / Q000276:immunology; D007252:Influenza Vaccines / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D014613:Vaccines, Attenuated / Q000276:immunology
D007252:Influenza Vaccines; D014613:Vaccines, Attenuated
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