[Regional intra-arterial infusion in combination chemotherapy with IFN-beta, MMC and 5-FU (beta-MF chemotherapy) in liver tumors].
The effect of combination chemotherapy with Interferon-beta, Mitomycin C and 5-fluorouracil (beta-MF chemotherapy) on 7 hepatic tumors by intra-arterial administration was studied. Complete remission (CR) was observed in one patient and partial remission (PR) in two patients, the efficacy rate being 42.9%. The survival period was more than one year in 6 patients. Fever was observed in 6 cases, although it was slight in all cases and preventable by pre-treatment with antipyretics. The authors consider that beta-MF chemotherapy can be expected to be one form of treatment for nonresectable gastrointestinal carcinoma.
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007269:Injections, Intra-Arterial; D007370:Interferon Type I / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D008937:Mitomycins / Q000008:administration & dosage
D007370:Interferon Type I; D008937:Mitomycins; D005472:Fluorouracil