Inhibitory activity of sphingomyelin on hemolytic activity of coelomic fluid of Holothuria polii (Echinodermata).
The hemolytic activity of coelomic fluid from Holothuria polii is specifically inhibited by sphingomyelin. This phospholipid is the constituent of the membrane which probably interacts with the hemolysin thereby leading to the lysis.
D000818:Animals; D001419:Bacteria / Q000276:immunology; D001826:Body Fluids / Q000276:immunology; D002784:Cholesterol; D003169:Complement Inactivator Proteins / Q000494:pharmacology; D004447:Echinodermata / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology; D006461:Hemolysis / Q000187:drug effects*; D010743:Phospholipids / Q000494:pharmacology; D012616:Sea Cucumbers / Q000276:immunology*; D013108:Sphingomyelin Phosphodiesterase / Q000378:metabolism; D013109:Sphingomyelins / Q000494:pharmacology
D003169:Complement Inactivator Proteins; D010743:Phospholipids; D013109:Sphingomyelins; D002784:Cholesterol; D013108:Sphingomyelin Phosphodiesterase