[Tumors of the brain vascular plexuses caused by the avian myeloblastosis virus].
A series of experiments on the induction of tumours in the central nervous system with the help of avian myeloblastosis virus was carried out. 142 highly sensitive and inbred chickens, 1 or 2 days of age, were used. The intracerebral virus dose was 0.01-0.02 ml. The titer was 10(9)--10(12) PFU/ml. 25 tumours of choroid plexus were induced during the experiments, 3 tumours developed in the control after intravenous inoculation. Out of 33 chickens highly sensitive to AMV tumours of choroid plexus were found in 6 (15.1%), and out of 75 inbred chickens tumours were found in 16 (21.3%). Three main stages of experimental tumours development in the brain choroid plexus were identified and their pathomorphological description was given. A relatively big amount of choroid plexus tumours have developed upon the brain inoculation with avian myeloblastosis virus. This might be attributed to blastomogenic virus action.
D000818:Animals; D001353:Avian Leukosis / Q000150:complications* / Q000473:pathology; D009189:Avian Myeloblastosis Virus; D001921:Brain / Q000098:blood supply* / Q000473:pathology; D001932:Brain Neoplasms / Q000209:etiology* / Q000473:pathology; D002645:Chickens; D002831:Choroid Plexus
Opukholi sosudistykh spleteniĭ golovnogo mozga, vyzvannye virusom mieloblastoza ptits.