title: Therapeutic response interactions between timolol maleate and dipivefrin hydrochloride.
abstract: Twenty-one patients on long-term treatment with topical timolol maleate and dipivefrin hydrochloride were studied to assess the effect of each agent when used in combined therapy. The two agents are partially additive in most patients, but the relative contribution of each agent varies widely in individual patients and in separate diagnostic categories.
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D004837:Epinephrine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005901:Glaucoma / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D013999:Timolol / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D009883:Ophthalmic Solutions; D013999:Timolol; C015173:dipivefrin; D004837:Epinephrine