title: Effect of intravitreal silicone oil on intraocular pressure.
abstract: We analyzed data obtained prospectively on 48 consecutive patients treated with intravitreal silicone oil. Forty percent were diabetic. Follow-up ranged from three to eight months. An increase in intraocular pressure (IOP) (defined as a rise 10 mmHg above the preoperative level) developed in 56% of the eyes in the postoperative period (range, 10 to 53.4 mmHg; mean rise, 21.63 mmHg). There was no significant difference in mean pressure rise between diabetic and non-diabetic eyes. The increase in IOP was transient in 78% of the patients. In 70% the IOP rose to a level greater than 22 mmHg. All of these patients required medical treatment, and some silicone oil was removed in six. Only 22% of those requiring treatment still received medication at follow-up. No patient in this series had uncontrolled IOP.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012827:Silicone Oils / Q000009:adverse effects*; D014821:Vitrectomy; D014822:Vitreous Body / Q000187:drug effects*
chemical_list: D012827:Silicone Oils