Vocal cord paralysis in postpoliomyelitis syndrome.
Postpoliomyelitis syndrome is characterized by new neuromuscular symptoms, including weakness, developing years after recovery from acute polio. Bilateral vocal cord paralysis is presented as a new manifestation of this syndrome. Other clinical features of post-poliomyelitis syndrome in this report are discussed. The etiology of this syndrome is unknown, though attrition or immune-mediated destruction of collateral muscular innervation appears likely. The pathologic findings include scattered individual muscle fiber atrophy as well as evidence of chronic denervation and reinnervation. This form of motor deterioration is not life-threatening, but potentially may cause increasing disability in a large number of polio survivors. Proper supportive care of facial, laryngeal, and pharyngeal weakness is crucial in the management of these patients.
D001706:Biopsy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009132:Muscles / Q000294:innervation / Q000473:pathology; D009133:Muscular Atrophy / Q000473:pathology; D011051:Poliomyelitis / Q000150:complications* / Q000473:pathology; D013577:Syndrome; D013997:Time Factors; D014826:Vocal Cord Paralysis / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology