Recommended precautions when using low-osmolality or nonionic contrast agents with vasodilators.
Low-osmolality contrast agents were tested for potential chemical incompatibility with vasodilators commonly used in angiography. A mixture of Hexabrix and papaverine produced a white crystalline precipitate. Hexabrix and tolazoline exhibited transient immiscibility. Injection of a flush solution between vasodilator and contrast agent is recommended as a precaution.
D000792:Angiography / Q000379:methods*; D011232:Chemical Precipitation; D003287:Contrast Media / Q000008:administration & dosage* / Q000009:adverse effects; D004347:Drug Interactions; D006801:Humans; D066298:In Vitro Techniques; D009994:Osmolar Concentration; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000009:adverse effects
D003287:Contrast Media; D014665:Vasodilator Agents