[Dose-response curves for the action of 6 MeV mean-energy neutrons on a human lymphocyte culture at different stages of the mitotic cycle].
A linear component was predominant in the dose-response curve characterizing the radiosensitivity of human lymphocyte chromosomes after exposure to fast neutrons (E = 6 MeV) at different mitotic cycle stages. This was indicative of a single-hit mechanism of the formation of chromosome aberrations after the effect of 6 MeV neutrons. It is suggested that the plateau of the dose-response curve at the S-stage may be considered as an indication of repair of damages induced by neutrons at this stage.
D002478:Cells, Cultured; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D005214:Fast Neutrons; D006801:Humans; D008214:Lymphocytes / Q000166:cytology / Q000528:radiation effects*; D008938:Mitosis / Q000528:radiation effects*; D009502:Neutrons; D012044:Regression Analysis
Krivye doza--éffekt pri deĭstvii neĭtronov so sredneĭ énergieĭ 6 MéV na kul'turu limfotsitov cheloveka v razlichnykh stadiiakh mitoticheskogo tsikla.