[Torre-Muir syndrome. Sebaceous gland tumors indicate colon carcinoma and other internal malignant tumors].
The Torre-Muir syndrome belongs to a group of hereditory cancers and expresses itself in the occurrence of cutaneous gland tumors and (often multiple) carcinoma of the colon. The syndrome is probably a phenotypical manifestation of the "cancer family" syndrome, in which familial carcinoma of the colon also occurs. A case of Torre-Muir syndrome in a 43-year-old man is described. Because of the dermatological features, the colon carcinoma was diagnosed in time. Family investigations revealed another case of complete Torre-Muir syndrome, as well as a remarkable frequency of colon carcinoma in one family branch. Inheritance is autosomal dominant. The characteristic morphological features of the sebaceous gland neoplasias makes an early, often life-saving, diagnosis possible.
D000328:Adult; D003110:Colonic Neoplasms / Q000235:genetics* / Q000473:pathology; D005153:Facial Neoplasms / Q000473:pathology / Q000556:secondary; D006801:Humans; D007636:Keratoacanthoma / Q000209:etiology / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D012004:Rectal Neoplasms / Q000235:genetics* / Q000473:pathology; D012626:Sebaceous Gland Neoplasms / Q000235:genetics / Q000473:pathology / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary*; D013577:Syndrome
Das Torre-Muir-Syndrom. Talgdrüsentumoren signalisieren Kolonkarzinome und andere interne Malignome.