Antibody response after a two-year intradermal booster of rabies human diploid cell vaccine.
A study was undertaken to evaluate the effectiveness of a low dose of rabies human diploid cell vaccine administered intradermally for preexposure booster inoculation. Seventy-six volunteers received a 0.1-ml dose of rabies human diploid cell vaccine intradermally, approximately 2 years after their primary series. Though only 25 (32.9%) had a titer less than 0.5 IU/ml before the booster, all had a postbooster titer of greater than or equal to 4.0 IU/ml 3 weeks later. Five of 73 (6.8%) reported an allergic reaction after the booster.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D002648:Child; D005260:Female; D006801:Humans; D007117:Immunization, Secondary; D008297:Male; D008875:Middle Aged; D011818:Rabies / Q000517:prevention & control*; D011819:Rabies Vaccines / Q000627:therapeutic use*; D011820:Rabies virus / Q000276:immunology*
D000914:Antibodies, Viral; D011819:Rabies Vaccines