Evaluation of an improved fiberoptics luminescence skin monitor with background correction.
In this work, an improved version of a fiberoptics luminescence monitor, the prototype luminoscope II, is evaluated for in situ quantitative measurements. The instrument was developed to detect traces of luminescing organic contaminants on skin. An electronic background-nulling system was designed and incorporated into the instrument to compensate for various skin background emissions. A dose-response curve for a coal liquid spotted on mouse skin was established. The results illustrated the usefulness of the instrument for in vivo detection of organic materials on laboratory mouse skin.
D000818:Animals; D003031:Coal / Q000032:analysis; D005069:Evaluation Studies as Topic; D005336:Fiber Optic Technology; D008163:Luminescent Measurements; D051379:Mice; D008819:Mice, Nude; D008991:Monitoring, Physiologic / Q000295:instrumentation; D012867:Skin / Q000187:drug effects*
D003031:Coal