Guillain-Barré syndrome after vaccination with purified tetanus toxoid.
A 47-year-old patient had Guillain-Barré syndrome after the injection of pure tetanus toxoid. He demonstrated a hypersensitive lymphoblastic transformation to purified tetanus antigen, and typing for disease-associated antigens showed him to be homozygous for HLA-B8. This is the first reported case of nonrelapsing Guillain-Barré syndrome after tetanus toxoid vaccination.
D000062:Accidents, Occupational; D006259:Craniocerebral Trauma / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D011129:Polyradiculoneuropathy / Q000209:etiology*; D013745:Tetanus Toxoid / Q000009:adverse effects*; D014611:Vaccination / Q000009:adverse effects*
D013745:Tetanus Toxoid