Mechanical characterisation of human postburn hypertrophic skin during pressure therapy.
Postburn hypertrophic scar commonly occurs among the Chinese resulting from serious burn injuries. A non-invasive method of preventing and controlling such scars is using pressure therapy. Its mechanical properties are used as a quantitative indicator for scar assessment and maturation. The non-linear properties of the skin tissue are characterised in this study by a modulus of elasticity and a percentage extension (strain) at load intensities of 20, 40 and 100 g. The latter is a measure of the scar extensibility while the former the scar stiffness. A correlation is obtained between the clinical scar grading and these mechanical properties. Altogether 300 individual measurements were made on fifteen Chinese patients of ages ranging from 18 to 44 with burn injuries of superficial to whole skin thickness burns which necessitated surgical graft procedures. This in vivo study of the mechanical properties of hypertrophic scar tissue lasted 2 yr.
D000293:Adolescent; D000328:Adult; D001458:Bandages / Q000009:adverse effects*; D001696:Biomechanical Phenomena; D002056:Burns / Q000150:complications* / Q000628:therapy; D002681:China; D002921:Cicatrix / Q000208:ethnology / Q000209:etiology* / Q000473:pathology; D004548:Elasticity; D006801:Humans; D006984:Hypertrophy; D011312:Pressure / Q000009:adverse effects*; D012867:Skin / Q000473:pathology*