[Determination of estradiol receptors in the endometrium--a contribution to the diagnosis of functional sterility].
In 86 cases of female infertility an endometrial biopsy was performed. The received tissues were examined by histological methods and the binding of estradiol on the specific cytoplasmic receptor was studied. Serum levels of estradiol and progesterone were estimated at the same day.--The estradiol receptor levels from ovulatory cycles are directly dependent on the histological dated phase of the menstrual cycle. The level was highest in late proliferative phase and declines during the secretory phase.--Luteal phase deficiency and other luteal phase defects are connected with a decrease of estrogen receptor concentrations in secretory endometrium.
D000328:Adult; D001706:Biopsy; D004717:Endometrium / Q000473:pathology*; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000175:diagnosis* / Q000473:pathology; D008597:Menstrual Cycle; D011374:Progesterone / Q000097:blood; D011959:Receptors, Estradiol / Q000378:metabolism*; D011960:Receptors, Estrogen / Q000378:metabolism*
D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D011374:Progesterone; D004958:Estradiol
Die Bestimmung der Estradiolrezeptoren im Endometrium--ein Beitrag zur Diagnostik der funktionellen Sterilität.