[Comparative studies of the distribution of hepatitis B markers among blood donors and patients with post-transfusion hepatitis in the city of Sofia].
The incidence of HBsAg, anti-HBs, HBeAg and anti-HBe was studied in blood donor via various methods. HBsAg was established in 0.9 to 1.2% on the average among the blood donors paid; in 1.4 to 3.9% among the unpaid ones and 4.7 to 5.1% among the blood donors from organized population groups. Anti-HBs was established in 14.2%, HBeAg in 13.6% and anti-HBe in 38.2% from the HBsAg positive. With the comparative juxtaposition in the post-transfusion hepatitis (PTH) among the patients admitted to hospital for viral hepatitis a tendency was established to reduction from 0.9% for the period before the testing of the blood donors for HBsAg, 7.5% for the period tested by immunoelectrophoresis (IEP), and 4.5% for the period tested by reversal passive hemagglutination (RPHA). Patients HBsAg-positive were established by IEP in 39.2% on the average and by RPHA in 48.6%. A relative increase is reported of non-B PTH, non-A, non-B PTH in particular, with the introduction of more sensitive methods for investigations of blood donors for hepatitis B markers.
D001782:Blood Donors; D002031:Bulgaria; D004797:Enzyme-Linked Immunosorbent Assay; D006386:Hemagglutination Tests; D006509:Hepatitis B / Q000453:epidemiology*; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006513:Hepatitis B e Antigens / Q000032:analysis*; D006801:Humans; D007122:Immunoelectrophoresis; D065227:Transfusion Reaction
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens
Sravnitelni prouchvaniia vurkhu razprostranenieto na gepatitni B-markeri sred kruvodariteli i sred zaboleli ot posttransfuzionen khepatit v gr. Sofiia.