[A myasthenic episode following intake of large amounts of a beta blocker].
A transient myasthenic syndrome confirmed by EMG after taking large doses of beta blocking agent is reported. Data on similar complications have not been found in the literature. Theories trying to explain the myasthenic, myopathic effect of the beta-blocking agents are reviewed. In the opinion of the authors the quinidine-like membrane stabilising effect played a role in their case, although the possibility of the direct effect of the drug on the neurotransmitters cannot be excluded either.
D000328:Adult; D004576:Electromyography; D005260:Female; D006801:Humans; D009132:Muscles / Q000187:drug effects; D009157:Myasthenia Gravis / Q000139:chemically induced*; D011433:Propranolol / Q000506:poisoning*; D013406:Suicide, Attempted
D011433:Propranolol
Myasthenische Episode nach Einnahme grosser Mengen Betablocker.