Intraneural lipoma of the sciatic nerve.
A large, well-encapsulated intraneural lipoma occurred within the sciatic nerve of a 34-year-old woman. In a review of the literature, significant differences were noted between the well-encapsulated and the diffusely infiltrative lipofibromatous hamartoma types of intraneural lipomas. The average age at the time of appearance of the well-encapsulated type is 45 years, with female predominance, while the infiltrative type arises in a younger age group (average age, eight years) with no sexual predominance. To avoid a recurrence, total excision is recommended in cases of the well-encapsulated type. Attempts to excise the diffusely infiltrative type are likely to fail.
D000328:Adult; D005260:Female; D006801:Humans; D008067:Lipoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D010524:Peripheral Nervous System Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D012584:Sciatic Nerve; D014057:Tomography, X-Ray Computed