title: Chronic eyelid closure and its effect upon the human cone and rod electroretinogram.
abstract: The human rod and cone systems have different spectral and adaptive sensitivities. Ganzfeld electroretinogram responses show that chronic eyelid closure, such as extensive symblepharon, can lead to dark-adaptation of the rods but simultaneously permit light-adaptation of the cones of the same eye. This effect is due to the red-filtering properties of the closed eyelid and the differential sensitivity of the two photoreceptor systems to the long wavelengths.
mesh_terms: D000368:Aged; D002908:Chronic Disease; D004596:Electroretinography; D005141:Eyelid Diseases / Q000503:physiopathology*; D005260:Female; D006801:Humans; D010786:Photoreceptor Cells / Q000503:physiopathology*; D000267:Tissue Adhesions / Q000503:physiopathology