title: [Volatile fractions of essential oil-based phytoncides as a component of therapeutic-rehabilitative complexes in chronic bronchitis].
abstract: Three samples of essential oil (EO) were studied. Experiments on the cultures of human fetal lung fibroblasts showed 2 samples of EO in concentrations of 0.25-2.5 micrograms/ml to considerably stimulate DNA synthesis. Spray administration of one of the samples to guinea-pigs in line with egg powder sensitization for two more days resulted in a complete discontinuation of the respiratory allergic reaction to inhalation of a resolving dose of the antigen 12 days after sensitization. The evaluation of 96 patients with chronic bronchitis (mainly obstructive) subjected to daily 40-minute stay in the atmosphere containing natural concentrations (about 0.1 mg/m3) of EO volatile fractions, showed a significant increase in the permeability of the respiratory tracts (Tiffeneau's index) and a decrease in IgE total serum level.
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D001991:Bronchitis / Q000628:therapy*; D002908:Chronic Disease; D004247:DNA / Q000096:biosynthesis; D006801:Humans; D006967:Hypersensitivity / Q000517:prevention & control; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008875:Middle Aged; D009822:Oils, Volatile / Q000494:pharmacology / Q000627:therapeutic use*; D010938:Plant Oils / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D009822:Oils, Volatile; D010938:Plant Oils; D004247:DNA
vernacular_title: Letuchie fraktsii fitontsidov na osnove éfirnykh masel v sostave lechebno-reabilitatsionnykh kompleksov pri khronicheskikh bronkhitakh.