title: The effect of lumbar puncture procedure on blood glucose level and leukocyte count in infants.
abstract: Blood glucose level, urea concentration, and total white blood cell count were determined both before and 10-15 minutes after lumbar puncture (LP) procedure in 26 infants suspected of having meningitis. There was a significant (p less than 0.001) increase in the peripheral white blood cell (WBC) count (mean +/- standard deviation) from 10,960 +/- 3,500 cells/microliter before to 13,300 +/- 3,970 cells/microliter following the LP procedure, due to relative rise in the neutrophils and lymphocytes. Blood glucose levels did not change significantly following this procedure (85.3 +/- 13.4 mg/dl and 84.1 +/- 12.6 mg/dl respectively). An LP procedure does not impair correct cerebrospinal fluid glucose/blood glucose determination but may cause elevation of peripheral WBC count.
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D005947:Glucose / Q000134:cerebrospinal fluid; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007958:Leukocyte Count; D008581:Meningitis / Q000175:diagnosis; D010976:Platelet Count; D011446:Prospective Studies; D013129:Spinal Puncture; D014508:Urea / Q000097:blood
chemical_list: D001786:Blood Glucose; D014508:Urea; D005947:Glucose