Bone morphology in primary hyperparathyroidism--a qualitative and quantitative study of 391 cases.
The changes of trabecular bone in primary hyperparathyroidism were studied in 391 iliac crest bone biopsies. In 60 unselected cases a histomorphometric analysis was performed. The classical osteoitis fibrosa is very rare in our material (4%). Only 49% of the cases developed specific endosteal fibrosis, 46% had increased remodelling surfaces and in 1% it was not possible to detect any difference in comparison to age-related controls. For diagnostic purposes the investigation is not helpful in nearly 50%.
D001706:Biopsy; D001861:Bone Regeneration; D001862:Bone Resorption / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology*; D006801:Humans; D006961:Hyperparathyroidism / Q000473:pathology*; D010006:Osteoblasts / Q000473:pathology; D010010:Osteoclasts / Q000473:pathology