title: Accuracy and precision of breath alcohol measurements for subjects in the absorptive state.
abstract: Published data are analyzed in order to estimate the accuracy of breath-alcohol measurements for subjects during absorption of orally ingested ethanol. Simultaneous measurements of breath alcohol concentration (BrAC) and venous blood alcohol concentration (VBAC) show that actual VBAC can be overestimated by more than 100% for a significant amount of time after drinking stops. The maximum error found for four individual subjects is +230%, +190%, +60%, and +30%. The magnitude of these errors indicates that results from quantitative evidential breath alcohol analyzers are far less accurate for the absorptive state than they are during the postabsorptive state, but the specifications for accuracy and precision given by manufacturers of these instruments do not reflect this. The results also indicate that there is a significant likelihood that subjects will be in the absorptive state when tested under field conditions. I conclude that estimates of BAC based on BrAC measurements are not reliable in the absorptive state and that the uncertainty associated with such estimates should be accounted for, particularly when the results are used in connection with law enforcement.
mesh_terms: D000042:Absorption; D001944:Breath Tests / Q000592:standards*; D003951:Diagnostic Errors; D000431:Ethanol / Q000032:analysis* / Q000097:blood; D005554:Forensic Medicine; D006801:Humans; D013997:Time Factors
chemical_list: D000431:Ethanol