Quantitative measurements of retinal edema by specific gravity determinations.
We have quantified retinal edema in rat by specific gravity measurements in vitro. Specific gravity corresponds to tissue water content, which is increased in retinal edema. The gravimetric analysis of retinal edema corresponds well with light and transmission electron microscopy and radiolabelled albumen studies. Specific gravity measurements are the standard method to measure brain edema and are also applicable to the measurement of retinal edema.
D000818:Animals; D005260:Female; D006861:Hydrogen Peroxide; D007511:Ischemia / Q000473:pathology; D010211:Papilledema / Q000209:etiology / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000098:blood supply; D012161:Retinal Artery; D013046:Specific Gravity
D006861:Hydrogen Peroxide