Inflammatory bowel disease and X chromosome abnormalities. A case report.
An abnormal sex chromosome constitution (45,X/46,XX) was observed in a woman with Crohn's disease and multiple spontaneous abortions. Immunologic disorders, inflammatory bowel disease and X chromosome abnormalities appear to be positively associated. Awareness of this association may result in detection of an otherwise unsuspected sex chromosome abnormality.
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D006801:Humans; D011247:Pregnancy; D012729:Sex Chromosome Aberrations / Q000150:complications*; D014960:X Chromosome