[Polyploidization of rat hepatocytes induced by x-ray radiation at different periods of the cell cycle].
As determined by the yield of polyploid hepatocytes after X-irradiation of rats with a dose of 6 Gy the S-stage of the cell cycle was most radiosensitive; as to the yield of cells with chromosome aberrations the middle of the G1-stage was the most radiosensitive period of the cell cycle. The differences in the radiosensitivity of the cell cycle stages indicated that although primary lesions were similar molecular mechanisms leading to tre final effect were essentially different.
D000818:Animals; D002453:Cell Cycle / Q000528:radiation effects; D002869:Chromosome Aberrations; D004247:DNA / Q000528:radiation effects; D008099:Liver / Q000166:cytology / Q000528:radiation effects*; D008297:Male; D011123:Polyploidy; D011836:Radiation Tolerance; D051381:Rats; D013997:Time Factors
D004247:DNA
Poliploidizatsiia gepatotsitov krys, indutsirovannaia rentgenovskim izlucheniem v razlichnykh periodakh kletochnogo tsikla.