title: Effect of Eimeria acervulina infection on chick (Gallus domesticus) high density lipoprotein composition.
abstract: 1. Plasma high density lipoprotein (HDL), the principal carotenoid carrier in broiler chicks, was analyzed at zero time and 3, 5 and 7 days after inoculation of chicks with the intestinal coccidial parasite, Eimeria acervulina. 2. Infection caused significant decreases in total HDL mass from 3 through 7 post-inoculation (PI), and decreases in relative percents of protein and carotenoids, and relative increases in phospholipid and cholesterol esters by 7 days PI. 3. Carotenoid content correlated best with protein content (principally apolipoprotein A-I) throughout the experiment. 4. Findings emphasize the importance of the small intestinal mucosa as a source of plasma HDL in the broiler chick, and suggest that apolipoprotein A-I is the binding site for HDL carotenoids.
mesh_terms: D000818:Animals; D002338:Carotenoids / Q000097:blood; D002645:Chickens / Q000469:parasitology*; D002850:Chromatography, Gel; D003048:Coccidiosis / Q000097:blood / Q000662:veterinary*; D004591:Electrophoresis, Polyacrylamide Gel; D008075:Lipoproteins, HDL / Q000097:blood*; D011201:Poultry Diseases / Q000097:blood*
chemical_list: D008075:Lipoproteins, HDL; D002338:Carotenoids