A common progenitor for neurons and glia persists in rat retina late in development.
Retrovirus-mediated gene transfer was used to mark cell lineages in vivo in the postnatal rat retina. Labelled clones contained up to three different cell types: three types of neurons or two types of neurons and a Müller glial cell. This indicates that a single retinal progenitor can generate remarkably diverse cell types near the end of development.
D000375:Aging; D000818:Animals; D002472:Cell Transformation, Viral; D005814:Genes, Viral; D009457:Neuroglia / Q000166:cytology / Q000502:physiology*; D051381:Rats; D012160:Retina / Q000166:cytology / Q000254:growth & development* / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000166:cytology / Q000502:physiology*; D012190:Retroviridae / Q000235:genetics