Distribution, excretion and in-vivo metabolism of 14C-hexachlorobenzene and the influence of iron overload in C57BL/10 mice.
Iron overload did not greatly alter the distribution and total excretion of radioactivity from 14C-hexachlorobenzene (HCB) in male C57Bl/10 mice. An increase was observed in the urinary excretion of metabolites but its significance is unclear.
D000818:Animals; D002250:Carbon Radioisotopes; D002722:Chlorobenzenes / Q000378:metabolism*; D006581:Hexachlorobenzene / Q000378:metabolism*; D007501:Iron / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D014018:Tissue Distribution
D002250:Carbon Radioisotopes; D002722:Chlorobenzenes; D006581:Hexachlorobenzene; D007501:Iron