[Asymptomatic hypokalemia and hypomagnesemia with renal cation loss (Gitelman syndrome)].
Hypokalemia with hyperkaliuresis was diagnosed in a 10 1/4-year-old boy, who presented with spontaneously disappearing abdominal pain. The diagnosis of Gitelman-Syndrome (asymptomatic chronic hypokalemia and -magnesemia) was established after detection of hypomagnesemia, renal magnesium losing but normal renin-angiotensin-aldosterone system and glomerular filtration rate. After oral supplementation of potassium hypokalemia persisted and hyperkaliuresis increased. The substitution was discontinued, the hyperkaliuresis diminished and the child remained asymptomatic during a 24 months follow-up. The substitution of potassium and magnesium can be avoided in children with Gitelman-Syndrome as long as they remain asymptomatic.
D002648:Child; D002908:Chronic Disease; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D007008:Hypokalemia / Q000652:urine*; D008274:Magnesium / Q000652:urine*; D008275:Magnesium Deficiency / Q000652:urine*; D008297:Male; D011188:Potassium / Q000652:urine*; D012084:Renin-Angiotensin System
D008274:Magnesium; D011188:Potassium
Asymptomatische Hypokaliämie und Hypomagnesiämie mit renalem Kationenverlust (Gitelman-Syndrom).