The progression of personality changes in senile dementia of the Alzheimer's type.
Passive, agitated, and self-centered behavioral changes were noted on initial evaluation in two-thirds, one-third, and one-third, respectively, of subjects with mild senile dementia of the Alzheimer's type (SDAT). Over a 50-month follow-up period, the percentage of patients who exhibited agitated and self-centered behaviors doubled. The percentage of subjects who demonstrated all three behavioral changes increased from 11% at entry to the study (mild SDAT) to over 50% when the dementia had reached a severe stage. The presence of personality changes at a mild stage of dementia did not predispose subjects to more rapid progression to a more advanced stage of illness.
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000523:psychology*; D001519:Behavior / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010551:Personality; D010552:Personality Assessment; D013997:Time Factors