Pulmonary hypertension complicating portal hypertension. A case report with suggestions for a different therapeutic approach.
The pulmonary hypertension of a patient with portal vein thrombosis was not responsive to various vasodilator drugs. The high cardiac output permitted the use of atenolol. The pulmonary artery pressure (PAP) was lowered from 105/50 to 87/31 mmHg. The effect was sustained after 6 months of treatment: PAP 68/32 mmHg.
D000328:Adult; D001262:Atenolol / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications*; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D008297:Male
D001262:Atenolol