Purine salvage as metabolite and energy saving mechanism in Camelus dromedarius: the recovery of guanine.
The preservation of purine ring as purine bases appears to be a common feature of camel liver. Hepatic guanine appears to be actively converted into GMP in the camel rather than further degraded. The limiting step of guanine degradation appears to be the lack of hepatic guanase activity. Higher purine bases over uric acid ratios were found in camel urine with respect to those of zebu.
D000818:Animals; D002162:Camelus / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D004734:Energy Metabolism; D006147:Guanine / Q000378:metabolism*; D006148:Guanine Deaminase / Q000378:metabolism; D019271:Hypoxanthine; D007042:Hypoxanthines / Q000097:blood / Q000378:metabolism / Q000652:urine; D008099:Liver / Q000201:enzymology*; D011687:Purines / Q000378:metabolism*; D014969:Xanthine Oxidase / Q000378:metabolism
D007042:Hypoxanthines; D011687:Purines; D019271:Hypoxanthine; D006147:Guanine; D014969:Xanthine Oxidase; D006148:Guanine Deaminase; C030985:purine