Binding of n-mers to one-dimensional lattices with longer than close-contact interactions.
A general formalism is derived for the evaluation of binding isotherms of n-mers (ligands) to one-dimensional polymers in the presence of ligand-ligand interactions which extend over several binding sites with distance-dependent interaction energies (multi-parameter model). This is an extension of the usual n-mer binding theory developed by several investigators in which ligand-ligand interaction occurs only when two ligands are in close contact (one-parameter model). The difference in binding isotherms between a one-parameter model and a multi-parameter model is studied numerically using the present formalism.
D001704:Biopolymers; D007700:Kinetics; D008024:Ligands; D046911:Macromolecular Substances; D008433:Mathematics; D008962:Models, Theoretical
D001704:Biopolymers; D008024:Ligands; D046911:Macromolecular Substances