[Concentration of acid-soluble metabolites--middle molecules in the blood of bronchial asthma patients].
The level of the derivatives of protein and lipid metabolism increases in the blood of patients with bronchial asthma (BA) and chronic asthmatic bronchitis (CAB), in particular that of peroxide radicals, the products of lipid peroxidation (LPO), the fraction of acid soluble metabolites--average mass molecules (AMM). The blood acquires unusual toxicity. The content of AMM in the blood of BA and CAB patients shows correlation with LPO and is in direct relation to severity of clinical symptoms. The removal of toxic products from the body by hemosorption promotes clinical remission and a decrease in AMM and LPO levels.
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000097:blood* / Q000378:metabolism / Q000628:therapy; D001991:Bronchitis / Q000097:blood; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000097:blood; D008054:Lipid Peroxides / Q000096:biosynthesis; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D008970:Molecular Weight; D009842:Oligopeptides / Q000097:blood*; D012141:Respiratory Tract Infections / Q000097:blood
D008054:Lipid Peroxides; D009842:Oligopeptides; D008315:Malondialdehyde
Soderzhanie kislotorastvorimykh metabolitov--molekul sredneĭ massy v krovi bol'nykh bronkhial'noĭ astmoĭ.