title: [Analysis of the pharmacokinetics of ethanol injected intraperitoneally and intravenously in rats with different levels of initial alcohol motivation].
abstract: Ethanol pharmacokinetics was studied after its intraperitoneal and intravenous administration in rats with different initial level of alcohol motivation using gas chromatography. It was shown that in general pharmacokinetic pattern studied upon both intraperitoneal and intravenous ethanol administration (with respect to resorption and/or distribution), the rate of ethanol elimination including a number of processes leading to a decreased drug content may be an important criterion for the selection of animals with distinct initial levels of alcohol motivation.
mesh_terms: D000428:Alcohol Drinking / Q000502:physiology*; D000818:Animals; D004198:Disease Susceptibility; D000431:Ethanol / Q000008:administration & dosage / Q000097:blood*; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D007700:Kinetics; D008297:Male; D009042:Motivation / Q000502:physiology*; D051381:Rats; D013997:Time Factors
chemical_list: D000431:Ethanol
vernacular_title: Analiz farmakokinetiki étanola pri ego vnutribriushinnom i vnutrivennom vvedenii v krovi krys s razlichnym urovnem iznachal'noĭ alkogol'noĭ tivatsii.