Cardiovascular and biochemical assessment in migraine patients submitted to tilt test.
Ten migraine patients underwent a tilt test both during migraine attack and headache-free interval, and the following parameters were assessed: plasma levels of norepinephrine (NE), and serum dopamine beta hydroxylase (D beta H), systolic and diastolic blood pressure and heart rate (SBP, DBP, HR). SBP during the tilt test showed a fall greater than 30 mmHg in 2 cases in the headache-free interval and in 4 cases during migraine attack. In migraine patients in headache-free interval, tilt test increased NE and D beta H as it did in the control group, while in migraine attack tilt test increased NE and D beta H less than in the control group. This impairment of the sympathetic nervous system during the migraine attack is discussed.
D000328:Adult; D001794:Blood Pressure; D004299:Dopamine beta-Hydroxylase / Q000097:blood*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology*; D009638:Norepinephrine / Q000097:blood*; D011187:Posture; D013564:Sympathetic Nervous System / Q000503:physiopathology*
D004299:Dopamine beta-Hydroxylase; D009638:Norepinephrine