The influence of topical anaesthetic agent at bronchoalveolar lavage upon cellular yield and identification and upon macrophage function.
The influence of cocaine and lignocaine as local anaesthetic agent upon the results obtained at bronchoalveolar lavage was investigated. No differences were found. A functional activity of macrophages was assessed when the cells were stored in lavage fluid. A time-dependent decrease occurred which was related to lack of nutrients rather than the anaesthetic concentration.
D001980:Bronchi / Q000473:pathology*; D001984:Bronchial Neoplasms / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002452:Cell Count / Q000187:drug effects; D003042:Cocaine / Q000494:pharmacology*; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology*; D008264:Macrophages / Q000187:drug effects* / Q000502:physiology; D011650:Pulmonary Alveoli / Q000473:pathology*; D012507:Sarcoidosis / Q000473:pathology; D007507:Therapeutic Irrigation
D008012:Lidocaine; D003042:Cocaine