Diuretic effect of metoprolol.
Metoprolol caused a significant (P less than 0.001) increase in urine output in rabbits. There was no change in serum sodium concentration but serum potassium levels increased significantly. The most probable mechanism of action was increase in renal blood flow and glomerular filtration rate.
D000818:Animals; D004231:Diuresis / Q000187:drug effects*; D006801:Humans; D008790:Metoprolol / Q000494:pharmacology*; D011817:Rabbits
D008790:Metoprolol