A stochastic process approach to the development of atheroma.
This study aims at formulating a dynamic model of particle sedimentation as applied to lipoprotein deposition during atheroma progression. The basic assumption is that all particles are identical and that the number of sedimented particles is relatively great. It is hypothised that sedimentation of a given particle is random; according to the theory of stochastic processes, the probability of a certain number of particles to sediment or deposit changes with time. The stochastic approach may explain some aspects of atherosclerosis development, i.e. its progression or regression.
D000818:Animals; D001158:Arteries / Q000473:pathology / Q000502:physiology; D001161:Arteriosclerosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism*; D008954:Models, Biological; D011336:Probability; D013269:Stochastic Processes
D008074:Lipoproteins