Effect of environmental temperature changes on liver delta 6 and delta 5 fatty acid desaturases depressed by hyperglycidic diet on male rats.
Male rats maintained on a control diet at 24 C and shifted to 12 C for five days showed no modification in delta 6 or delta 5 desaturase activity. When delta 6 and delta 5 desaturase activities were diminished by a hyperglycidic diet, shifting to cold increased both enzymatic activities. In general, modifications observed in liver microsomal fatty acid composition are consistent with those associated with the enzymatic desaturation activity.
D000818:Animals; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D044943:Fatty Acid Desaturases / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013696:Temperature
D004040:Dietary Carbohydrates; D044943:Fatty Acid Desaturases; D005947:Glucose