Gd(+)Cuiabá, a new rare glucose-6-phosphate dehydrogenase variant presenting normal activity.
A 33-year-old Brazilian male of Portuguese extraction was found to have a new glucose-6-phosphate dehydrogenase variant, herein named Gd(+)Cuiabá. The enzyme variant is characterized by normal activity, normal electrophoretic mobility, high Km for glucose-6-phosphate, high Ki for NADPH, decreased thermal stability, normal utilization of substrate analogues and normal pH curve.
D000328:Adult; D001938:Brazil; D005954:Glucosephosphate Dehydrogenase / Q000097:blood / Q000235:genetics*; D006801:Humans; D007527:Isoenzymes / Q000097:blood / Q000235:genetics*; D008297:Male; D009154:Mutation
D007527:Isoenzymes; D005954:Glucosephosphate Dehydrogenase