[Mechano-chemical properties of actomyosin-ADP complexes in rabbit psoas muscle fibers].
The relaxing effect of vanadate on active contractile system is found to be completely absent from rigor skinned fibres with ADP even on their stretching up to the forces comparable with the active ones, though vanadate is likely to bind not very firmly with crossbridges not containing inorganic phosphate. Probable reasons of such distinction are considered. The complex actomyosin-ADP in the rigor fibres is supposed to have significantly lower free energy independently of its deformation than the one of the same composition in the active ones. Possible role of different actomyosin-ADP states in the mechanochemical cycle of crossbridge is discussed.
D000205:Actomyosin / Q000378:metabolism*; D000244:Adenosine Diphosphate / Q000378:metabolism*; D000818:Animals; D001696:Biomechanical Phenomena; D004734:Energy Metabolism; D066298:In Vitro Techniques; D007537:Isometric Contraction / Q000187:drug effects; D009126:Muscle Relaxation / Q000187:drug effects; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*; D011817:Rabbits; D014638:Vanadates; D014639:Vanadium / Q000494:pharmacology
D014639:Vanadium; D014638:Vanadates; D000244:Adenosine Diphosphate; D000205:Actomyosin
Mekhanokhimicheskie svoĭstva kompleksov aktomiozin-ADF v voloknakh m. psoas krolika.