title: Acute chondrolysis complicating Legg-Calvé-Perthes disease.
abstract: Of 270 children with Legg-Calvé-Perthes (LCP) disease, roentgenographic evidence of chondrolysis was noted in 12 (4.5%) within one year after diagnosis and appropriate management. Only in six hips of these 12 patients did the retrospective clinical, histological, and orthopedic findings fulfill the diagnostic requirements for chondrolysis. Sequential roentgenographic findings included initial periarticular osteoporosis and subchondral cortical irregularities, subsequent narrowing of the joint space, premature fusion of the growth plate, and eventual development of degenerative arthritis. The early roentgenographic recognition of chondrolysis is emphasized because it has an untoward effect on the prognosis of LCP and should therefore prompt a different orthopedic approach.
mesh_terms: D000208:Acute Disease; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging*; D006801:Humans; D007873:Legg-Calve-Perthes Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D011859:Radiography