Multicentric early adenocarcinoma involving stomach and duodenum.
Six separate foci of superficial adenocarcinoma were seen in the first part of the duodenum of a 53-year-old man with a multicentric superficial adenocarcinoma of the stomach. To our knowledge, duodenal involvement in such a tumor has not been reported before. The duodenal foci were partly covered by gastric-type surface epithelium, suggesting that they might have arisen in areas of gastric metaplasia or heterotopia.
D000230:Adenocarcinoma / Q000473:pathology*; D000428:Alcohol Drinking; D004379:Duodenal Neoplasms / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D012907:Smoking; D013274:Stomach Neoplasms / Q000473:pathology*