Renal adenocarcinoma and end stage kidney disease.
The association of end stage kidney disease with cystic degeneration and renal adenocarcinoma was first recognized in 1977. Since then a number of reports have confirmed this relationship. Duration of dialysis has been the most strongly associated risk factor. We report 8 cases of end stage kidney disease and renal adenocarcinoma. Median duration of hemodialysis was approximately 1 year, and 3 patients never had hemodialysis. Factors other than duration of dialysis, such as toxic metabolites, toxins from dialysis tubing, polyamines or other carcinogens, may be as or more important.
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000150:complications*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D013997:Time Factors; D014057:Tomography, X-Ray Computed