Olfactory neuroblastoma metastatic to the eye.
A case of olfactory neuroblastoma metastatic to the choroid is reported and described. Histologically, the tumor consisted of islands of small round cells, many of them surrounding blood vessels in a 'pseudorosette' pattern. Numerous mitotic figures were present. Transmission electron microscopy reveals neuritic processes containing neurosecretory granules and microtubules, features characteristic of olfactory neuroblastoma. This is the first published case of an olfactory neuroblastoma demonstrating intraocular metastasis.
D002830:Choroid Neoplasms / Q000556:secondary* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008875:Middle Aged; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000556:secondary* / Q000648:ultrastructure; D009669:Nose Neoplasms; D009831:Olfactory Mucosa