Aged erythrocytes exhibit decreased anion exchange.
The rate of transport of [32P] phosphate into human and bovine erythrocytes and of a spin-label analogue of phosphate (Tempo-phosphate) into human erythrocytes was found to decrease with increasing erythrocyte age by 15-20% when comparing 20% most dense cells with 20% of lightest cells. The activation energy of Tempo-phosphate transport did not show significant changes upon erythrocyte aging.
D000818:Animals; D001693:Biological Transport, Active; D002417:Cattle; D003497:Cyclic N-Oxides; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007474:Ion Exchange; D007700:Kinetics; D010710:Phosphates / Q000097:blood*; D013113:Spin Labels
D003497:Cyclic N-Oxides; D010710:Phosphates; D013113:Spin Labels; C003959:TEMPO