title: Dental findings in osteogenesis imperfecta: II. Dysplastic and other developmental defects.
abstract: Orthopantomograms of 49 patients with osteogenesis imperfecta (OI) classified according to Sillence were examined for dysplastic dentin defects and other developmental abnormalities of the teeth. Thistle-tube-shaped pulps in the permanent teeth were observed in five patients. Four of them had pulp stones in several teeth. Apically extended pulp chambers were present in 3/49 patients, and the structure of the mandible was cystic in 1/49. These defects occurred in patients with type I or unclassifiable OI and were mainly not associated with type I dentinogenesis imperfecta (DI). The prevalence rates of invaginations (10.2%) and hypodontia of permanent teeth (18.4%) exceeded those in the normal population. The frequent developmental disturbances of the teeth in OI may be secondary to the connective tissue defect. The relation of the dysplastic defects other than type I DI to OI remains to be clarified.
mesh_terms: D003238:Connective Tissue / Q000473:pathology; D003782:Dental Pulp / Q000473:pathology; D003811:Dentinogenesis Imperfecta / Q000235:genetics / Q000473:pathology; D006801:Humans; D007570:Jaw Cysts / Q000235:genetics / Q000473:pathology; D008336:Mandibular Diseases / Q000235:genetics / Q000473:pathology; D010013:Osteogenesis Imperfecta / Q000235:genetics / Q000473:pathology*; D014071:Tooth Abnormalities / Q000235:genetics / Q000473:pathology