[Development of radiation injuries and recovery processes in the hematopoietic tissue of mice after repeated exposure to fast neutrons and gamma-irradiation].
A study was made of the number of CFUs and karyocytes in thigh bone and the concentration of functional cells in the peripheral blood of mice subjected to fast neutron- and gamma-irradiation four times at a 60-day interval (210 cGy per fraction). The regenerating potential decreased and the half-recovery time T1/2 increased in the haemopoietic tissue as the number of fractions and total absorbed dose increased. The dependence of T1/2 on the equivalent radiation dose was as follows: T1/2 = T1/2(0)e0.0009D.
D000818:Animals; D003114:Colony-Forming Units Assay; D004307:Dose-Response Relationship, Radiation; D005214:Fast Neutrons; D005720:Gamma Rays; D006412:Hematopoietic Stem Cells / Q000473:pathology / Q000528:radiation effects*; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D011836:Radiation Tolerance
Nekotorye zakonomernosti formirovaniia radiatsionnogo porazheniia i razvitiia vosstanovitel'nykh protsessov v krovetvornoĭ tkani mysheĭ posle povtornykh vozdeĭstviĭ bystrykh neĭtronov i gamma-izlucheniia.