title: Stress proteins in the human endometrium and decidua.
abstract: Protein synthesis in response to heat shock was induced in the proliferative and secretory human endometrium as well as in human decidua during a 2-h incubation period at 41 degrees C. A major 70 K stress protein and two minor stress proteins of 88 and 94 K were detected after [35S]methionine incorporation followed by SDS polyacrylamide gel electrophoretic separation and autoradiography of dried gels. Two dimensional isoelectric focusing followed by fluorography showed the major 70 K stress protein to consist of at least six polypeptides of pH 4.6 to 5.5, the 88 K to consist of at least four polypeptides, of pH 5.5 to 6.0, and the 94 K to consist of at least three polypeptides of pH 4.6 to 5.2. Stress proteins in the human endometrium and decidua may prove to be of physiological significance in reproductive events.
mesh_terms: D003656:Decidua / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D004717:Endometrium / Q000032:analysis*; D005260:Female; D005470:Fluorometry; D006360:Heat-Shock Proteins / Q000032:analysis*; D006358:Hot Temperature; D006801:Humans; D008970:Molecular Weight
chemical_list: D006360:Heat-Shock Proteins