Monoamine oxidase inhibitory and anticonvulsant properties of some newer indolylimidazolones.
Newly synthesized indolylimidazolones were tested for their in vitro monoamine oxidase (MAO) inhibitory activity. These compounds were found to possess analgesic activity and anticonvulsant activity against maximal electroshock-induced convulsions in mice. The low toxicity of these compounds was reflected by their high approximate LD50 values.
D000700:Analgesics; D000818:Animals; D000927:Anticonvulsants; D007093:Imidazoles / Q000494:pharmacology*; D066298:In Vitro Techniques; D007928:Lethal Dose 50; D051379:Mice; D008996:Monoamine Oxidase Inhibitors; D051381:Rats
D000700:Analgesics; D000927:Anticonvulsants; D007093:Imidazoles; D008996:Monoamine Oxidase Inhibitors