Spontaneous premature chromosome condensation in metastatic variants of the B16 murine melanoma and human astrocytomas in culture.
Spontaneous premature chromosome condensation (PCC) occurs in B16 murine melanoma variants and two human astrocytoma cell lines in the absence of physical fusion of interphase and mitotic cells. There was no apparent relationship between PCC incidence and metastatic ability.
D000818:Animals; D001254:Astrocytoma / Q000235:genetics*; D002459:Cell Fusion; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D006801:Humans; D007399:Interphase; D008546:Melanoma, Experimental / Q000235:genetics*; D051379:Mice; D009362:Neoplasm Metastasis