Plasma exchange treatment in autoimmune hemolytic anemia of the warm antibody type with renal failure.
A patient with autoimmune hemolytic anemia of the warm antibody type developed a hyperacute hemolytic crisis with acute renal failure under conventional treatment with corticosteroids. Because of the life-threatening situation it was decided to start a combined treatment with immunosuppression and plasmapheresis. Already after the first plasma exchange the direct antiglobulin test became weakly positive, the hemoglobin level rose from 4.1 to 8.1 g/dl, and the hemolytic crisis subsided. Four more exchanges were performed; thereafter, the patient's clinical condition and laboratory data stabilized.
D058186:Acute Kidney Injury / Q000150:complications / Q000628:therapy; D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D003298:Coombs Test; D006801:Humans; D008297:Male; D010951:Plasma Exchange; D006435:Renal Dialysis; D012805:Sickle Cell Trait / Q000150:complications / Q000188:drug therapy
D000305:Adrenal Cortex Hormones