Flow characteristics of red cell containing fluids through pores. The effect of filter plugging, a mathematical model.
A mathematical model was developed that describes the effects of filter plugging on flow through 3 micron pore polycarbonate filters as a function of time, pressure, and cell concentration, both under stirring and nonstirring conditions. The mathematical constants for the model were derived from experimental data generated with a filtration apparatus, and were tested by using various concentrations of cells that are able to plug filter pores. A computer simulation program was written to test the model over a wide range of nonfilterable cell concentrations.
D001783:Blood Flow Velocity; D003198:Computer Simulation; D004907:Erythrocyte Deformability; D004912:Erythrocytes / Q000502:physiology*; D008433:Mathematics; D008954:Models, Biological; D012212:Rheology; D014462:Ultrafiltration