Co-solubility in binary phospholipid crystals.
Crystalline binary solid solutions of phosphatidylethanolamines are obtained when various fractions of compounds with different chain lengths are dissolved in chloroform and allowed to evaporate to dryness. Phase diagrams and electron diffraction measurements on chain mixtures with a difference of two or four methylene groups indicate that solubility is continuous, although non-ideal. Average molecular volume appears to increase according to Vegard's rule although deviations are noted. These deviations are similar to those observed for binary paraffin solids. Substitution of ether-links for ester-links in one component does not alter solubility behavior. In general the rules of solid solution formation appear to conform to those originally proposed by Kitaigorodskii [1961) Organic Chemical Crystallography, pp. 231-240, Consultants Bureau, New York).
D002152:Calorimetry, Differential Scanning; D055598:Chemical Phenomena; D002621:Chemistry; D003460:Crystallization; D008854:Microscopy, Electron; D010714:Phosphatidylethanolamines; D012995:Solubility
D010714:Phosphatidylethanolamines; C007510:1,2-dipalmitoyl-3-phosphatidylethanolamine; C007445:1,2-dilauroylphosphatidylethanolamine; C018525:1,2-dimyristoylphosphatidylethanolamine