[Value of complamin and seduxen in the correction of hemodynamic disorders of epileptic children and adolescents].
Children and adolescents with an unfavourable course of epilepsy received a multiple modality treatment including complamin (xantinolnicotinate). Thirty of the 36 patients showed positive response which was twice as much as in patients receiving only anticonvulsive drugs. The study of the cerebral hemodynamics with the help of regional cerebral blood flow determination by means of intravenous administration of 133Xe and REG showed a tendency to normalization of the vascular supply to the brain. In 66 of the 87 epileptic patients studied the employment of diazepam improved the microcirculation of the cerebral tissue and the venous outflow from the cranial cavity which allows the recommendation of diazepam as a vasoactive agent.
D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000098:blood supply; D002561:Cerebrovascular Disorders / Q000188:drug therapy* / Q000503:physiopathology; D002648:Child; D003975:Diazepam / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004827:Epilepsy / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D010992:Plethysmography, Impedance; D012039:Regional Blood Flow; D013806:Theophylline / Q000031:analogs & derivatives*; D014971:Xanthinol Niacinate / Q000627:therapeutic use*; D014980:Xenon Radioisotopes
D000927:Anticonvulsants; D014980:Xenon Radioisotopes; D014971:Xanthinol Niacinate; D013806:Theophylline; D003975:Diazepam
Znachenie komplamina i seduksena v korrektsii gemodinamicheskikh narusheniĭ u deteĭ i podrsotkov, bol'nykh épilepsieĭ.