Compound-action potentials of myelinated fibers in the saphenous nerve of the dog: in situ electrophysiologic and behavioral studies.
Compound-action potentials (CAP) were recorded directly from the surface of fascicles of the distal portion of the saphenous nerve (SN) of dogs in situ. Potentials were evoked through needle electrodes and were recorded through bipolar stainless steel electrodes. Stimuli of 10-microseconds duration and of 0.4 +/- 0.15-mA amplitude evoked a monophasic CAP. Sensory conduction velocities of afferent fibers, the action potentials of which contributed to this evoked compound potential, ranged from 62.4 +/- 2.8 m/s for the most rapidly conducting fibers to 30.5 +/- 2.4 m/s for the least rapidly conducting fibers. Stimuli of 25-microseconds duration and of 2.2 +/- 0.8-mA amplitude evoked a second, longer latency CAP in addition to the first CAP. Sensory conduction velocities of afferent fibers, the action potentials of which contributed to this evoked compound potential, ranged from 20.4 +/- 2.9 m/s for the most rapidly conducting fibers to 13.7 +/- 1.0 m/s for the least rapidly conducting fibers. Low-amplitude, negative peaks were recorded between the first and second major potentials elicited by the longer duration stimuli. Stimuli of still longer duration and higher currents induced contractions of the caudal part of the sartorius muscle by current spread in 9 of 12 dogs. In 3 dogs, a third monophasic CAP was evoked, having a maximal conduction velocity of 1.7 +/- 0.2 m/s. After section of the distal portion of the SN on one side in each of 2 dogs, an absence of signs of sensory deficit was found on clinical neurologic examination. The area of cutaneous innervation of the cranial branch of the distal portion of the SN was determined electrophysiologically.
D000200:Action Potentials; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D004285:Dogs / Q000502:physiology*; D004594:Electrophysiology; D005260:Female; D006614:Hindlimb / Q000294:innervation*; D008297:Male; D009413:Nerve Fibers, Myelinated / Q000502:physiology*