Effect of combinations of antioxidants on oxygen radical-induced sister chromatid exchanges.
Oxygen radical scavengers significantly reduced the number of sister chromatid exchanges in Chinese hamster ovary cells exposed to an oxygen radical-generating enzyme system. When vitamin E was combined with these antioxidants, no genetic toxicity was observed.
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002374:Catalase / Q000494:pharmacology; D002460:Cell Line; D006224:Cricetinae; D005609:Free Radicals; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D013482:Superoxide Dismutase / Q000494:pharmacology; D014810:Vitamin E / Q000494:pharmacology
D000975:Antioxidants; D005609:Free Radicals; D014810:Vitamin E; D002374:Catalase; D013482:Superoxide Dismutase