title: Lack of beneficial effect of intensive topical steroids and beta irradiation of eyes undergoing repeat trabeculectomy.
abstract: Sixteen eyes (14 patients) that had previous failed trabeculectomy underwent a further trabeculectomy. In the postoperative period they were treated with intensive topical steroids (hourly) for several months. At the end of one year the overall results of surgery were not improved using this regime when compared with a previously reported series of similar patients who were treated with less steroid. It appeared that the addition of more intensive topical steroid usage was no more successful than steroids given in a four-time-a-day program. Additionally, some eyes were treated with beta irradiation, which did not appear to influence the results. Eyes that had a limbus-based conjunctival flap at reoperation had a more favorable outcome than those having fornix-based flaps.
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D001610:Beta Particles; D003131:Combined Modality Therapy; D003228:Conjunctiva / Q000601:surgery; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D012086:Reoperation; D014129:Trabecular Meshwork / Q000601:surgery*
chemical_list: D011239:Prednisolone