title: [HIV seropositivity and pregnancy. Apropos of 48 cases (how should they be managed at the present time?)].
abstract: We describe the gynaecological and obstetrical management of 48 HIV seropositive, pregnant women and review the literature. We did not find that pregnancy aggravated the development of the condition from the asymptomatic anti-HIV related complex (ARC) and AIDS. It seemed that fetal malformations, especially of the face, occurred most frequently in babies born to HIV seropositive mothers. Materno-fetal transmission of HIV was found in the uterus in 50% of our cases. In conclusion, we recommend safe contraception to prevent pregnancies in anti HIV seropositive women. If that fails, induced first trimester abortion is medically indicated and should be carried out if possible, as should strict medical control post-partum of both mother and child if the pregnancy is carried to term.
mesh_terms: D000386:AIDS-Related Complex / Q000628:therapy; D000032:Abortion, Therapeutic; D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control / Q000628:therapy* / Q000635:transmission; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D003267:Contraception; D005260:Female; D006678:HIV / Q000276:immunology*; D006801:Humans; D007232:Infant, Newborn, Diseases / Q000517:prevention & control; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000628:therapy*; D011446:Prospective Studies; D012189:Retrospective Studies
chemical_list: D000914:Antibodies, Viral
vernacular_title: Séropositivité HIV et grossesse. A propos de 48 observations (quelle conduite à tenir pratique adopter aujourd'hui?)