title: Comparison of specificity of human and horse leucocyte proteinases with synthetic peptide substrates.
abstract: Highly purified horse leucocyte proteinases 1, 2A and 2B hydrolyze synthetic substrates which are decomposed also by human leucocyte elastase but they are unable to hydrolyze typical substrates of cathepsin G. Thus in distinction to other mammalian species horse leucocytes are devoid of cathepsin G and contain only elastases.
mesh_terms: D000818:Animals; D056649:Cathepsin G; D002403:Cathepsins / Q000097:blood; D006736:Horses / Q000097:blood*; D006801:Humans; D006868:Hydrolysis; D007700:Kinetics; D007962:Leukocytes / Q000201:enzymology*; D009842:Oligopeptides / Q000378:metabolism*; D010196:Pancreatic Elastase / Q000097:blood*; D012697:Serine Endopeptidases; D013379:Substrate Specificity
chemical_list: D009842:Oligopeptides; D002403:Cathepsins; D012697:Serine Endopeptidases; C534094:CTSG protein, human; D056649:Cathepsin G; D010196:Pancreatic Elastase