title: [Microbiological research on the secretion of the normal parotid glands and in acute and chronic non-mumps parotitis in children].
abstract: The qualitative and quantitative compositions of the microbial flora of the parotid gland were investigated in 42 children with nonepidemic parotiditis. The pathogenic properties of the microbial flora were the most pronounced in acute purulent and purulent necrotic parotiditis as compared to those in aggravation and remission of chronic parotiditis. In children with acute or chronic recurring parotiditis during its aggravation there was observed a significant increase in the number of the coccal organisms in the mixture of saliva and secretion of the parotid gland. Direct relationship between the aggravation activity and the number of the microbes was noted which testified to lowering of the protective functions of the oral cavity tissues. With an account of the presence of microorganisms in the clinically intact salivary glands it was concluded that the microbial factor was secondary in etiology of parotiditis. Quantitative estimation of bacteria in the mixture of saliva and parotid gland secretion is important for antibacterial therapy of the disease which is advisable when 1 ml of secretion of the affected glands contains 10(5) microorganisms. Their antibiotic sensitivity tests are obligatory.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008826:Microbial Sensitivity Tests; D010306:Parotid Gland / Q000378:metabolism / Q000382:microbiology*; D010309:Parotitis / Q000209:etiology / Q000382:microbiology*; D013210:Staphylococcus / Q000187:drug effects / Q000302:isolation & purification; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Mikrobiologicheskie issledovaniia sekreta okoloushnykh sliunnykh zhelez v norme, pri ostrom i khronicheskom neépidemicheskom parotite u deteĭ.