[Hemosiderin findings in the liver, spleen and lung in newborn infants and infants].
The content and distribution of hemosiderin in the liver, spleen and lungs of stillborn children, newborns and infants were determined histologically by Perl's method (Prussian blue reaction). We describe a study of 59 deaths up to the age of 2 years. The hemosiderin content depends on age and decreases with increasing age. No relevant differences were found in cases of sudden infant death syndrome (SIDS). In the liver hemosiderin is localized preponderantly in the periphery of the lobules. The spleen shows a diffuse siderosis of the red pulp. Minimal intrapleural, septal and perivasal depositions of hemosiderin can be found in the lung tissue. The significance of these findings is discussed.
D005260:Female; D005313:Fetal Death / Q000473:pathology*; D006485:Hemosiderin / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008099:Liver / Q000473:pathology*; D008168:Lung / Q000473:pathology*; D011247:Pregnancy; D013154:Spleen / Q000473:pathology*; D013398:Sudden Infant Death / Q000473:pathology*
D006485:Hemosiderin
Hämosiderinbefunde in Leber, Milz und Lunge bei Neugeborenen und Säuglingen.