title: Qualitative and quantitative changes of acid and alkaline phosphatases in the testis and epididymis of mice in relation to single high dose of alpha-chlorohydrin.
abstract: The present study is designed to know whether the enzymes related to permeability and general metabolism of the cells of testis and epididymis are affected by alpha-chlorohydrin. For this purpose two enzymes, viz., acid and alkaline phosphatases are studied thoroughly by qualitative and quantitative parameters during single high dose (90 mg/kg body weight) treatment after 24 and 48 hours of drug administration. Along with this, the changes in the behaviour of the animals and histological structure of testis and epididymis of mice are also recorded.
mesh_terms: D000135:Acid Phosphatase / Q000032:analysis*; D000469:Alkaline Phosphatase / Q000032:analysis*; D000818:Animals; D002728:Chlorohydrins / Q000494:pharmacology*; D004822:Epididymis / Q000033:anatomy & histology / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D051379:Mice; D012726:Sexual Behavior, Animal / Q000187:drug effects; D013737:Testis / Q000033:anatomy & histology / Q000187:drug effects / Q000201:enzymology*; D013997:Time Factors; D000517:alpha-Chlorohydrin / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D002728:Chlorohydrins; D000517:alpha-Chlorohydrin; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase