Solitary labial papular acantholytic dyskeratoma in an immunocompromised host.
A 42-year-old white man presented with a solitary labial papule 4 years after cardiopulmonary transplantation. Pathological examination of the excised papule revealed a tumor with prominent acantholytic dyskeratosis. Risk factors for skin tumors in this patient included habitual tobacco chewing, chronic unprotected solar exposure, and an immunosuppressive regimen comprising prednisone and cyclosporin-A. This is the first report of an acantholytic dyskeratoma in association with these predisposing conditions.
D000051:Acantholysis / Q000209:etiology / Q000473:pathology*; D000328:Adult; D004817:Epidermis / Q000473:pathology*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008048:Lip Neoplasms / Q000209:etiology / Q000473:pathology*; D008297:Male; D010947:Plants, Toxic; D012871:Skin Diseases / Q000473:pathology*; D013472:Sunlight / Q000009:adverse effects; D014030:Tobacco, Smokeless