title: [Epidemiology of infection by LAV/HTLV-III virus in hemophiliacs multitransfused in France. Results of a survey conducted by 28 hemophilia centers].
abstract: In order to determine the contamination level of French hemophiliacs with the retrovirus LAV/HTLVIII, a national investigation of 1,670 hemophiliacs was performed. Results demonstrated that 49% were seropositive for LAV/HTLVIII antibodies. Of these 12.4% had clinical and/or biological symptoms of immunodeficiency. Regional differences with regard to the origin of blood used for plasma fractionation clearly appeared.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D000914:Antibodies, Viral / Q000032:analysis; D005602:France; D006678:HIV / Q000276:immunology; D006467:Hemophilia A / Q000150:complications* / Q000276:immunology / Q000628:therapy; D006801:Humans; D065227:Transfusion Reaction
chemical_list: D000914:Antibodies, Viral
vernacular_title: Epidémiologie de l'infection par le virus LAV/HTLVIII chez les hémophiles polytransfusés en France. Résultats d'une enquête menée par 28 centres d'hémophiles.