title: Suppurative splenitis and peritonitis in a horse after gastric ulceration caused by larvae of Gasterophilus intestinalis.
abstract: A 12-year-old Thoroughbred mare, with a history of anorexia, dramatic weight loss, fluctuating pyrexia and intermittent diarrhoea after an episode of colic, was presented for examination with depression, emaciation and ataxia. Thoracic and abdominal paracenteses yielded copious quantities of inflammatory exudate. Palpation per rectum revealed an enlarged spleen. The primary alterations in haematology included a severe leucocytosis with a left shift, and a hyperproteinaemia characterised by hypoalbuminaemia and hypergammaglobulinaemia. Post-mortem examination revealed a low grade pleurisy and peritonitis with fluid accumulation in both cavities. A suppurative gastritis with full thickness perforations of the stomach wall associated with Gasterophilus intestinalis larvae had extended to the juxtaposed organ initiating an extensive suppurative splenitis. Streptococcus zooepidemicus was cultured.
mesh_terms: D000818:Animals; D004175:Diptera; D005260:Female; D006734:Horse Diseases / Q000209:etiology* / Q000473:pathology; D006736:Horses; D007814:Larva; D009198:Myiasis / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D010439:Peptic Ulcer Perforation / Q000209:etiology / Q000662:veterinary; D010538:Peritonitis / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000209:etiology / Q000473:pathology / Q000662:veterinary; D013158:Splenic Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D013276:Stomach Ulcer / Q000209:etiology / Q000473:pathology / Q000662:veterinary*