Identification of factor XI deficiency in Holstein-Friesian cattle in Britain.
Blood coagulation tests were performed on dairy cattle in a herd with haemorrhagic problems on a farm in Gloucestershire. The characteristic pattern of prolonged partial thromboplastin time with normal prothrombin time and thrombin time was shown to be associated with a partial factor XI deficiency, a congenital defect previously identified in cattle in North America.
D000818:Animals; D001777:Blood Coagulation; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood*; D005173:Factor XI Deficiency / Q000097:blood / Q000662:veterinary*; D005260:Female; D010314:Partial Thromboplastin Time / Q000662:veterinary; D011517:Prothrombin Time / Q000662:veterinary; D013577:Syndrome / Q000662:veterinary; D013918:Thrombin Time / Q000662:veterinary; D006113:United Kingdom