The psychomotor development of full term infants whose mothers were treated with glucocorticosteroids during pregnancy.
The Development Quotient (D.Q.) was tested in 48 full term infants at the ages of 12-24 months who had been treated antenatally with Betamethasone to hasten pulmonary maturity. The results were compared with a control group of 100 normal full term infants of the same age. Although the two groups differed with respect to gestational age, there were no differences in birth weight, Apgar score and method of delivery between them. The results of the D.Q. evaluation showed no significant difference between the two groups. The assumption is made, therefore, that antenatal treatment with Glucocorticosteroids in the second and third trimester does not adversely affect the infant's psychological and motor development.
D001623:Betamethasone / Q000009:adverse effects* / Q000627:therapeutic use; D002657:Child Development / Q000187:drug effects; D005260:Female; D005325:Fetal Organ Maturity / Q000187:drug effects*; D006801:Humans; D006819:Hyaline Membrane Disease / Q000517:prevention & control*; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000196:embryology*; D009048:Motor Skills / Q000187:drug effects; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011597:Psychomotor Performance / Q000187:drug effects*
D001623:Betamethasone