title: The effect of a single large dose of amoxycillin on oral streptococci.
abstract: Salivary samples were examined for a period three weeks before, and three weeks after the administration of 3 g of amoxycillin in ten volunteers. There was a marked drop in the concentration of streptococci in all subjects in the first 4 h but most had substantially recovered within 48 h. All had recovered at seven days. No strains were resistant to 1 mg/l amoxycillin in the pre-treatment control series, and no resistant streptococci emerged.
mesh_terms: D000658:Amoxicillin / Q000494:pharmacology*; D006801:Humans; D010403:Penicillin Resistance; D012463:Saliva / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000658:Amoxicillin