title: Human sleep and circadian rhythms: a simple model based on two coupled oscillators.
abstract: We propose a model of the human circadian system. The sleep-wake and body temperature rhythms are assumed to be driven by a pair of coupled nonlinear oscillators described by phase variables alone. The novel aspect of the model is that its equations may be solved analytically. Computer simulations are used to test the model against sleep-wake data pooled from 15 studies of subjects living for weeks in unscheduled, time-free environments. On these tests the model performs about as well as the existing models, although its mathematical structure is far simpler.
mesh_terms: D001831:Body Temperature; D002940:Circadian Rhythm; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D009991:Oscillometry; D012890:Sleep / Q000502:physiology*