Classification of the stages of proliferative vitreoretinopathy in a refined experimental model in the rabbit eye.
Eighty-four rabbit eyes injected intravitreously with tissue-cultured fibroblasts following gas compression of the vitreous were examined clinically over a period of 1 month. Detailed clinical descriptions of the extent of retinal changes were recorded. Clinical landmarks were determined and arranged into a new classification of this model of proliferative vitreoretinopathy (PVR). The proposed classification will allow easier communication between research groups using this model to study the treatment and prevention of PVR.
D000818:Animals; D004195:Disease Models, Animal; D005128:Eye Diseases / Q000145:classification / Q000209:etiology / Q000473:pathology; D011817:Rabbits; D012164:Retinal Diseases / Q000145:classification* / Q000209:etiology / Q000473:pathology; D014822:Vitreous Body / Q000473:pathology