Rapid response of transient acantholytic dermatosis to selenium sulfide treatment for pityriasis versicolor.
The observation of a 51-year-old male patient with transient acantholytic dermatosis (TAD) is briefly reported. The discrete eruption, composed of erythematous escoriated papules and papulovesicles, moderately itching, was located on the back and chest, more permanent during the summer season. The biopsy revealed suprabasal acantholysis and Darier-like elements. Lesions of pityriasis versicolor, confirmed by microscopic examination and fluorescence in Wood's light, were intermingled with TAD in the same patient. A topical treatment with selenium sulfide brought TAD lesions to the disappearance in 1 week. Comments are made in relation with the possibility of Malassezia furfur to induce acantholytic phenomena.
D000051:Acantholysis / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012643:Selenium / Q000627:therapeutic use*; D018036:Selenium Compounds; D012871:Skin Diseases / Q000188:drug therapy*; D014010:Tinea Versicolor / Q000150:complications / Q000188:drug therapy*
D018036:Selenium Compounds; D012643:Selenium; C025698:selenium disulfide