Acanthamoeba keratitis.
A 41-year-old woman underwent a corneal transplant in her right eye because of a nonhealing ulcer. The graft failed within weeks of surgery and was eventually removed. Both the primary host cornea and the failed graft contained numerous Acanthamoeba cysts and trophozoites. Awareness of the causes of infectious keratitis should increase the likelihood of establishing the correct diagnosis.
D000328:Adult; D000562:Amebiasis / Q000473:pathology*; D000656:Amoeba / Q000302:isolation & purification; D003315:Cornea / Q000469:parasitology; D003320:Corneal Ulcer / Q000469:parasitology; D005260:Female; D006801:Humans; D007634:Keratitis / Q000469:parasitology*