The evaluation of postoperative irradiation in patients with early-stage ovarian cancer.
This is a retrospective study of 127 patients with ovarian carcinoma stage I, II, and III with no or minimal residual disease postoperatively. Patients were treated with radiotherapy by the moving strip technique from 1970 through 1984. The 5-year actuarial survival rate was 73%. Analysis was made on subgroups such as a complete versus incomplete staging procedure, stage, histopathology, grade, and amount of residual tumor. In this study, grade is a significant prognostic indicator (survival in grade 1 versus grade 2 and 3 tumors was statistically different (P less than 0.005). Stage 1 and 2 patients do better than stage 3 patients. Residual tumor does not influence survival rate. The disease-free survival of patients with serous cystadenocarcinoma is better than that of patients with mucinous cystadenocarcinoma (P less than 0.004). The incidence of severe complications was 4%.
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D003536:Cystadenocarcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D010052:Ovariectomy; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D012189:Retrospective Studies