title: [131I-accumulating pulmonary and bone metastases of differentiated thyroid cancer with low serum thyroglobulin levels--an exception in tumor follow-up?].
abstract: In the follow-up of differentiated thyroid carcinoma it is discussed whether the tumor-marker thyroglobulin can replace the 131I scan, especially when the thyroglobulin serum level is normal. A positive 131I scan of metastases in the follow-up of patients with differentiated thyroid carcinoma combined with a low serum thyroglobulin level is extremely rare. The literature shows a frequency of about 4%. Recently we found 3 cases with a positive 131I scan demonstrating pulmonary and bone metastases whereas the serum thyroglobulin level was low.
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000556:secondary*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes; D008175:Lung Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013954:Thyroglobulin / Q000097:blood*; D013964:Thyroid Neoplasms / Q000097:blood / Q000000981:diagnostic imaging*
chemical_list: D007457:Iodine Radioisotopes; D013954:Thyroglobulin
vernacular_title: 131J-speichernde pulmonale und ossäre Metastasen differenzierter Schilddrüsen-karzinome bei niedrigem Serum-Thyreoglobulinspiegel--Ausnahme in der Tumornachsorge?