Carcinoembryonic antigen (CEA) and two crossreacting antigens of 165 kD and 105 kD isolated from meconium exhibit identical amino terminal sequences.
Two antigens of 165 kD and 105 kD crossreacting with the carcinoembryonic antigen (CEA) were isolated from human meconium by perchloric acid extraction, differential immunoaffinity chromatography, and size exclusion HPLC. The sequences of the 30 amino terminal amino acids of both antigens are identical with the corresponding sequence of CEA.
D000595:Amino Acid Sequence; D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen / Q000276:immunology / Q000302:isolation & purification; D015815:Cell Adhesion Molecules; D003429:Cross Reactions; D006023:Glycoproteins / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D008470:Meconium / Q000276:immunology*; D008970:Molecular Weight
D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen; D015815:Cell Adhesion Molecules; D006023:Glycoproteins