Biomonitoring of industrial dusts on animals. II. Bioindication on alveolar macrophages.
Rats and rabbits were exposed through the respiratory system to industrial dusts (magnesite emissions, solid wastes from nickel refinery dump, cement emissions) at biomonitory stations or in experimental chamber. Following exposure the animals were killed, the alveolar macrophages isolated and acid phosphatase and beta-glucuronidase estimated in the isolated cells. The activity of both enzymes was enhanced in the exposed animals in all cases. The enhancement was dependent on the length of exposure and amount of inhaled particles.
D000135:Acid Phosphatase / Q000378:metabolism; D000393:Air Pollutants; D000818:Animals; D002126:Calcium Hydroxide; D004784:Environmental Monitoring / Q000379:methods*; D005260:Female; D005966:Glucuronidase / Q000378:metabolism; D007220:Industrial Waste; D008247:Lysosomes / Q000201:enzymology; D008264:Macrophages / Q000201:enzymology*; D009532:Nickel; D011247:Pregnancy; D011650:Pulmonary Alveoli / Q000201:enzymology; D011817:Rabbits; D051381:Rats
D000393:Air Pollutants; D007220:Industrial Waste; D009532:Nickel; D000135:Acid Phosphatase; D005966:Glucuronidase; D002126:Calcium Hydroxide