title: [Anesthesiological care of female patients with cerebrovascular aneurysms in pregnancy].
abstract: This is a report on a patient who suffered subarachnoid haemorrhage from an aneurysm of the a. cerebri media during the 28th week of pregnancy. The aneurysm was clipped under neuroleptanalgesia. Besides monitoring of heart rate, blood pressure and central venous pressure as well as the treatment parameters including end-expiratory CO2, the foetal heart rate was deduced by Doppler sonography. She was hyperventilated intraoperatively with a paCO2 of 3.8-4.1 kPa. During the actual aneurysm surgery, artificial hypotension by 20 mmHg to b.p. values around 100/160 mmHg was initiated by means of nitroglycerin. It is evident from the literature compiled on this occasion that it is mandatory to monitor foetal heart rate during controlled hypotension in pregnancy. Sodium nitroprusside should not be used to initiate artificial hypotension during pregnancy, since it may result in toxic cyanide levels in the foetus. As usual in neurosurgery, hyperventilation can be performed also during pregnancy, since placental blood flow decreases only if the CO2 concentration drops to a very low level.
mesh_terms: D000328:Adult; D000762:Anesthesia Recovery Period; D000773:Anesthesia, Obstetrical / Q000379:methods*; D005260:Female; D006801:Humans; D007023:Hypotension, Controlled / Q000379:methods; D002532:Intracranial Aneurysm / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D009458:Neuroleptanalgesia / Q000379:methods; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology / Q000601:surgery*; D011262:Pregnancy Trimester, Second; D013345:Subarachnoid Hemorrhage / Q000209:etiology / Q000503:physiopathology / Q000601:surgery
vernacular_title: Anästhesiologische Betreuung von Patientinnen mit Hirngefässaneurysmen in der Schwangerschaft.