title: Failure of Onchocerca gutturosa to develop in Simulium soubrense and Simulium yahense from Liberia.
abstract: Laboratory reared female S. soubrense and S. yahense from Liberia were intrathoracically inoculated with bovine skin dwelling microfilariae of Onchocerca gutturosa. Of a total of 174 flies, each injected with 50 fresh microfilariae, the maximum development was to late first-stage larvae. One S. soubrense also contained two second-stage larvae and a maldeveloped third-stage larvae. No development to normal third-stage larvae was observed in any fly despite maintenance at 28 degrees C for up to 10 days following infection. This contrasts with complete development of O. volvulus in both blackfly species under similar conditions.
mesh_terms: D000818:Animals; D005260:Female; D006790:Host-Parasite Interactions; D007303:Insect Vectors / Q000469:parasitology*; D007988:Liberia; D008842:Microfilariae / Q000254:growth & development; D009854:Onchocerca / Q000254:growth & development*; D012843:Simuliidae / Q000469:parasitology*