Incontinentia pigmenti: pigmentary changes independent of incontinence.
Incontinentia pigmenti is characterized by swirled hyperpigmentation associated with incontinence of pigment. A different pattern may be seen on the legs with light-colored atrophic scarred areas admixed with patches of normal but darker skin. Histologic examination confirms that the darker skin is normal without incontinence of pigment, while the light-colored skin lacks melanocytes and appendages but has dermal fibrosis.
D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D007184:Incontinentia Pigmenti / Q000235:genetics* / Q000473:pathology; D007223:Infant; D008544:Melanocytes / Q000473:pathology; D010859:Pigmentation Disorders / Q000235:genetics*; D012880:Skin Pigmentation