title: Nicotine fading, behavioral contracting, and extended treatment: effects on smoking cessation.
abstract: Twenty-eight subjects were randomly allocated to either a nicotine fading or a maintenance condition. The maintenance condition utilized behavioral contracting and extended treatment in addition to the nicotine fading to improve treatment outcome and avoid relapse. The maintenance condition achieved superior outcome on smoking measures at post-treatment and follow-up periods for self-reported smoking levels. Carbon monoxide levels were significantly lower for the maintenance condition at post-treatment, three month and six month follow-up. Saliva thiocyanate levels were significantly lower for the maintenance condition at the three month follow-up. Changes in health functioning indicated significantly lower diastolic and systolic blood pressure at six month follow-up for the maintenance condition. Additional research on nicotine regulation during nicotine fading and thiocyanate levels during experimental smoking would be useful. The use of behavioral contracting to enhance maintenance without therapeutic support warrants further research as well.
mesh_terms: D001521:Behavior Therapy / Q000379:methods*; D001794:Blood Pressure; D002248:Carbon Monoxide / Q000032:analysis; D005500:Follow-Up Studies; D006801:Humans; D009538:Nicotine / Q000008:administration & dosage*; D012463:Saliva / Q000032:analysis; D013861:Thiocyanates / Q000032:analysis; D014029:Tobacco Use Disorder / Q000628:therapy*
chemical_list: D013861:Thiocyanates; D009538:Nicotine; D002248:Carbon Monoxide; C031760:thiocyanate