title: [Transmission of amber mutants of bacteriophage T4. IV. The frequency of the phenomenon of temperature sensitivity of replication in non-permissive cells of amber mutants for the head genes].
abstract: Dependence of multiplication of 42 single and double amber mutants in 16 phage head genes on the incubation temperature was studied in the cells of non-permissive host. For amber mutants in 6 head genes the birst size decreases by several orders, with the increase of the incubation temperature. Among amber mutants of the above mentioned genes, mutants in genes 4 and 65 can be distinguished as those with considerably large burst size at low temperature. Phage head genes form the groups, according to temperature sensitivity of multiplication of amber mutants. These groups, together with corresponding groups of phage tail genes, constitute common temperature-sensitive and non-sensitive gene groups on the phage genomic map.
mesh_terms: D005814:Genes, Viral; D009154:Mutation; D013604:T-Phages / Q000235:genetics* / Q000502:physiology; D013696:Temperature; D014779:Virus Replication
vernacular_title: Izuchenie transmissii amber-mutantov bakteriofaga T4. Soobshchenie IV. Rasprostranennost' iavleniia termochuvstvitel'nosti razmnozheniia v nepermissivnykh kletkakh amber-mutantov po genam golovki.