[Pulsed radiolysis of aqueous solutions of serum albumin containing naphthoquinones].
As was shown by the pulse radiolysis method the simultaneous presence of naphthoquinone and human serum albumin molecules in an aqueous solution leads to the adsorption of the former on the surface of the latter. It is suggested that in these conditions the protein tertiary structure changes. New conformation reduces the reactivity of albumin toward the hydrated electron.
D006801:Humans; D007700:Kinetics; D009285:Naphthoquinones / Q000494:pharmacology*; D011487:Protein Conformation; D011837:Radiation-Protective Agents; D012709:Serum Albumin / Q000528:radiation effects*; D012996:Solutions
D009285:Naphthoquinones; D011837:Radiation-Protective Agents; D012709:Serum Albumin; D012996:Solutions
Impul'snyĭ radioliz vodnykh rastvorov syvorotochnogo al'bumina, soderzhashchikh naftokhinony.