[Activation of the blood kallikrein-kinin system as a cause of hemodynamic disorders during traumatic surgery of the liver and bile ducts].
Experimental and clinical studies have shown that surgical procedures on the liver and biliary tracts particularly accompanied by compression of the hepatoduodenal ligament in order to perform temporal hemostasis are followed by activation of kinin-formation. In most traumatic operations it exceeds the limits of regulatory mechanisms and is a cause of hemodynamic disturbances. Protease inhibitors are recommended to prevent such complications.
D000818:Animals; D001652:Bile Ducts / Q000601:surgery*; D004285:Dogs; D006439:Hemodynamics; D006801:Humans; D007610:Kallikreins / Q000097:blood*; D007705:Kinins / Q000097:blood*; D008099:Liver / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control; D011480:Protease Inhibitors / Q000627:therapeutic use
D007705:Kinins; D011480:Protease Inhibitors; D007610:Kallikreins
Aktivatsiia kallikrein-kininovoĭ sistemy krovi kak prichina vozniknoveniia narusheniĭ gemodinamiki pri travmatichnykh operatsiiakh na pecheni i zhelchnykh putiakh.