Inhibition of protein synthesis by an extract of the venom sac of the oriental hornet (Vespa orientalis).
Venom from young and adult hornets inhibit protein synthesis in human lymphocytes and platelets, but does not affect the synthesis of DNA and RNA. The venom activity is decreased by dialysis, and diminished more by boiling.
D000818:Animals; D001514:Bee Venoms / Q000633:toxicity*; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D004247:DNA / Q000096:biosynthesis; D005088:Exocrine Glands / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism; D009000:Monocytes / Q000378:metabolism; D014176:Protein Biosynthesis; D014862:Wasp Venoms / Q000633:toxicity*
D001514:Bee Venoms; D014862:Wasp Venoms; D004247:DNA