title: [Criteria for adequate plasma substitution in intensive plasmapheresis].
abstract: The authors analyzed 2 plasmosubstituting solutions of entirely different quantitative composition used during intensive plasmapheresis (47 procedures in 24 patients). Indices of central hemodynamics and blood oxygen-transport function served as criteria of the adequacy of plasmosubstitution. Plasmosubstitution in the volume of 110-130% to the volume of plasma exfusion was shown to preserve a stable volume of the circulating blood. Plasmosubstituting solutions should be composed of not less that 70% of protein and colloidal agents. Their lesser content (not more than 40%) revealed the development of noticeable disorder of blood oxygen-transportation function and decompensation of the blood circulation. In adequate plasmosubstitution change of the eukinetic type of blood circulation by the hyperkinetic one is a compensatory reaction of blood circulation.
mesh_terms: D000328:Adult; D000077324:Crystalloid Solutions; D006801:Humans; D011695:IgA Vasculitis / Q000628:therapy; D007552:Isotonic Solutions; D008875:Middle Aged; D009101:Multiple Myeloma / Q000628:therapy; D009103:Multiple Sclerosis / Q000628:therapy; D010952:Plasma Substitutes; D010956:Plasmapheresis / Q000379:methods*
chemical_list: D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D010952:Plasma Substitutes
vernacular_title: Kriterii adekvatnogo plazmozameshcheniia pri intensivnom plazmafereze.