Mechanism of urinary kallikrein excretion and its action on water excretion.
In male Wistar rats urinary kallikrein excretion was positively correlated with urinary flow and glomerular filtration rate and negatively with urinary osmolality and with TcH2O. The mechanism of urinary kallikrein excretion is interpreted as a wash-out effect of renal kallikrein. The renal kallikrein regulates the water excretion decreasing the reabsorption of water in the distal nephron.
D000818:Animals; D001834:Body Water / Q000502:physiology; D005919:Glomerular Filtration Rate; D007610:Kallikreins / Q000652:urine*; D007668:Kidney / Q000502:physiology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D007610:Kallikreins