title: [Aminoglutethimide in the treatment of metastasizing breast carcinoma in old age].
abstract: After first analyzing the basic pathophysiological aspects and the mechanism of action of aminoglutethimide, the authors report on their experience with the use of this steroid biosynthesis inhibitor in a group of geriatric patients with advanced cancer of the breast. After illustrating the results of their study, the authors conclude by stressing that the use of this drug appears to improve the quality of life of the patients with a significant increase in rates of complete or partial remission of the neoplastic disease.
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000616:Aminoglutethimide / Q000009:adverse effects / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy
chemical_list: D000616:Aminoglutethimide
vernacular_title: L'aminoglutetimide nel trattamento del carcinoma mammario metastatizzante in età geriatrica.