Tumour initiating activity of mancozeb--a carbamate fungicide in mouse skin.
Mancozeb is a protectant fungicide and is a polymeric complex of ethylene bis(dithiocarbamate)manganese (i.e. Maneb) with zinc salt. In this study, the tumour initiating ability of mancozeb has been observed by a 2-stage initiation-promotion protocol in mouse skin.
D000818:Animals; D002273:Carcinogens; D005260:Female; D008344:Maneb / Q000633:toxicity*; D051379:Mice; D010212:Papilloma / Q000139:chemically induced*; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D012878:Skin Neoplasms / Q000139:chemically induced*; D013755:Tetradecanoylphorbol Acetate / Q000633:toxicity; D013859:Thiocarbamates / Q000633:toxicity*; D015038:Zineb / Q000633:toxicity*
D002273:Carcinogens; D013859:Thiocarbamates; D008344:Maneb; D013755:Tetradecanoylphorbol Acetate; C013099:mancozeb; D015038:Zineb