title: [PMN elastase determination in tear fluid in corneal ulcer].
abstract: The PMN-Elastase concentration in tear fluid was determined in 87 persons without eye disease and compared with the PMN-elastase values of 28 patients with ulcus corneae. A significant increase in the PMN-elastase concentration was found in patients with ulcus corneae (means = 1196 micrograms/l) in comparison with the control group (means = 73 micrograms/l). The lapse control shows that the PMN-elastase values in the tear fluid of patients with ulcus corneae are elevated for a number of weeks, even though there are clinical signs of healing of the ulcer. The determination of PMN-elastase in tear fluid represents a new parameter indicating the real end of the inflammatory processes in the eye.
mesh_terms: D003320:Corneal Ulcer / Q000201:enzymology*; D006801:Humans; D009504:Neutrophils / Q000201:enzymology*; D010196:Pancreatic Elastase / Q000378:metabolism*; D013666:Tears / Q000201:enzymology*
chemical_list: D010196:Pancreatic Elastase
vernacular_title: PMN-Elastase-Bestimmung in der Tränenflüssigkeit bei Ulcus corneae.