title: [Quantitative characteristics of radiation injury of the spermatogenic epithelium and the rate of its recovery after exposure to fast neutrons and gamma-radiation].
abstract: The paper submits the results of studies on the kinetics of spermatogenous epithelium cell number after exposure to fast neutrons (60-300 cGy) and gamma-radiation (200-600 cGy). It was shown that a relative decrease in the quantity of spermatocytes is determined by an exponential dose-response curve with D0 of 35 and 120 cGy for neutrons and gamma-radiation respectively. For spermatides and spermatozoa a single D0 value of 20 and 55 cGy was obtained for neutrons and gamma-radiation respectively. As the radiation dose increases the recovery process in the epithelium is substantially decelerated. The equation T1/2 = T1/2(0)e0.0009D well describes the dependence of the half-recovery period T1/2 upon the equivalent dose.
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005214:Fast Neutrons; D005720:Gamma Rays; D008297:Male; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D011836:Radiation Tolerance; D012062:Relative Biological Effectiveness; D012670:Seminiferous Epithelium / Q000528:radiation effects*; D013079:Sperm Maturation / Q000528:radiation effects; D013737:Testis / Q000528:radiation effects*
vernacular_title: Kolichestvennaia kharakteristika radiatsionnogo porazheniia v spermatogennom épitelii i skorosti ego vosstanovleniia pri vozdeĭstvii bystrykh neĭtronov i gamma-izlucheniia.