Vasculitis in acute streptococcal glomerulonephritis.
Four children are described with a severe acute streptococcal glomerulonephritis. Olyguria, long term renal failure, arterial hypertension, nephrotic syndrome, unconsciousness, marked anemia, abdominal pain and gastrointestinal bleeding were the most prominent findings. The renal biopsy revealed a diffuse endocapillary glomerulonephritis with crescents and vasculitis. One patient had demonstrated multiorgan vasculitis. The patients were managed by conventional methods, three of them received anticoagulants of whom, two association of prednisolone-cyclophosphamide. All recovered.
D058186:Acute Kidney Injury / Q000209:etiology; D000925:Anticoagulants / Q000627:therapeutic use; D001167:Arteritis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000150:complications* / Q000188:drug therapy
D000925:Anticoagulants; D003520:Cyclophosphamide; D011239:Prednisolone