Influence of phalloidin on ATP hydrolysis during actin polymerization.
The influence of phalloidin on the ATP hydrolysis associated with actin polymerization was investigated. Whereas in the absence of phalloidin actin-bound ATP was totally hydrolyzed during polymerization, ATP hydrolysis was not complete after actin polymerization in the presence of phalloidin: 5-10% of ATP remained unhydrolyzed and disappeared only after 2 days.
D000199:Actins / Q000378:metabolism*; D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D006868:Hydrolysis; D007700:Kinetics; D009842:Oligopeptides / Q000494:pharmacology*; D010590:Phalloidine / Q000494:pharmacology*; D011108:Polymers; D011817:Rabbits
D000199:Actins; D009842:Oligopeptides; D011108:Polymers; D010590:Phalloidine; D000255:Adenosine Triphosphate