Computed tomography and angiography in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes); report of 3 cases.
Among mitochondrial encephalomyopathies, MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes, Pavlakis et al. 1983) is recognized as a distinct syndrome characterized by generalized convulsions and recurrent stroke-like episodes. The neuroradiological findings of three patients with MELAS are reported here. Retrospective review shows that MELAS should be included in the differential diagnosis of infarct-like lesions of the cerebrum.
D000140:Acidosis, Lactic / Q000150:complications / Q000000981:diagnostic imaging*; D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000150:complications / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008931:Mitochondria, Muscle / Q000473:pathology*; D009135:Muscular Diseases / Q000150:complications / Q000000981:diagnostic imaging*; D013577:Syndrome; D014057:Tomography, X-Ray Computed