title: Clonidine. An effective anti-manic agent?
abstract: Three patients suffering from bipolar affective disorder, manic phase, and who were resistant to conservative treatment were successfully treated with clonidine. This would support the nor-adrenergic hyperactivity theory of mania. The rapidity of action of clonidine and its lack of relatively serious side-effects renders it a potential alternative to conventional anti-manic agents.
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy*; D003000:Clonidine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D003000:Clonidine