Non-Hodgkin's lymphoma, HTLV-III/LAV, and HTLV-III/LAV antibody in the wife of a man with transfusion-acquired AIDS.
Non-Hodgkin's lymphoma of the small intestine developed in a 66-year-old woman who was the wife of a man with transfusion-related acquired immune deficiency syndrome (AIDS). Antibody to the human T lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) was present in her serum, and the virus was isolated from her peripheral lymphocytes. The possibility that the non-Hodgkin's lymphoma in this patient was a manifestation of HTLV-III/LAV infection is discussed. This is believed to be the first reported case of lymphoma occurring in a patient with documented HTLV-III/LAV infection outside the male homosexual risk group.
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000150:complications*; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis*; D005260:Female; D006678:HIV / Q000276:immunology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000097:blood / Q000209:etiology*; D008297:Male
D000914:Antibodies, Viral