Dose relationships in patients with early chloroquine retinopathy.
Thirty-five patients with bilateral irreversible chloroquine retinopathy have been identified prospectively since 1980. The dose relationships of chloroquine were examined specifically in these patients with particular reference to daily and total dose of chloroquine. Thirty of the 35 patients received 250 mg of chloroquine/day or less.
D002738:Chloroquine / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D012164:Retinal Diseases / Q000139:chemically induced*
D006886:Hydroxychloroquine; D002738:Chloroquine