A novel method for measuring the erythrocyte deformability, under oscillatory shear stress.
A novel apparatus for detecting a subtle decrease in erythrocyte deformability was developed. The oscillatory shape change of erythrocytes was monitored under an oscillatory shear stress (modulating the oscillation frequency in the range of 9-90 dyn/cm2). The ellipsoidal deformation of intact erythrocytes perfectly followed the oscillatory force of up to about 2 Hz, but the diamide-treated cells showed a phase difference of the oscillatory deformation at 1.7 Hz.
D004907:Erythrocyte Deformability; D006403:Hematologic Tests / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D009991:Oscillometry