title: [Analysis of specificity in the serodiagnosis of acquired immunodeficiency syndrome].
abstract: Analysis of serum samples for the presence of antibody to AIDS-inducing virus was carried out with the use of the Virognostika diagnosticum manufactured by Organon (the Netherlands). As a result, 6.1% of sera from patients with hematologic diseases, 5.7% of sera from oncologic patients, and 9.2% of sera from hepatitis B patients proved to be "positive" according to the criteria of the manufacturer. However the positively reacting sera could be neutralized by sorption on human red cells, groups AB and 0 and by treatment with the lysate of human lymphocyte culture, which was indicative of the fact that false positive reactions were probably due to the contamination of the antigenic preparation by components of the producer-cell membrane.
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis*; D000914:Antibodies, Viral / Q000032:analysis; D000936:Antigen-Antibody Complex / Q000032:analysis; D005069:Evaluation Studies as Topic; D005189:False Positive Reactions; D006678:HIV / Q000276:immunology; D006801:Humans; D011933:Reagent Kits, Diagnostic; D012306:Risk; D012698:Serologic Tests / Q000379:methods
chemical_list: D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex; D011933:Reagent Kits, Diagnostic
vernacular_title: Analiz spetsifichnosti serodiagnostiki sindroma priobretennogo immunnogo defitsita.