Neutropenia in cats with the Chediak-Higashi syndrome.
Thirteen cats with Chediak-Higashi syndrome and 22 control cats from the same colony, were evaluated for neutropenia. The absolute neutrophil counts of the Chediak-Higashi syndrome cats were significantly less (P less than 0.05) than those of the control cats. It is concluded that Chediak-Higashi syndrome cats, like Chediak-Higashi syndrome humans, have a neutropenia associated with the other manifestations of the syndrome. Lysozyme activity which was undetectable in the serum of both Chediak-Higashi syndrome and control cats was not of use for determining if the neutropenia was the result of neutrophil destruction.
D000380:Agranulocytosis / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000097:blood*; D002415:Cats; D002609:Chediak-Higashi Syndrome / Q000097:blood / Q000662:veterinary*; D005260:Female; D008297:Male; D009503:Neutropenia / Q000662:veterinary*