Lipofuscinosis of the human uterus.
A case of uterine lipofuscinosis in a patient with Friedreich's ataxia is described. Ultrastructural investigation confirmed the mitochondrial origin of the lipofuscin. Clinically, the patient suffered from brown bowel syndrome. Both the brown bowel syndrome and the uterine lipofuscinosis in the present case may be related to Friedreich's ataxia.
D000328:Adult; D005260:Female; D005621:Friedreich Ataxia / Q000473:pathology*; D006801:Humans; D008062:Lipofuscin / Q000032:analysis*; D008286:Malabsorption Syndromes / Q000473:pathology; D008854:Microscopy, Electron; D009215:Myometrium / Q000473:pathology; D010860:Pigments, Biological / Q000032:analysis*; D013577:Syndrome; D014591:Uterine Diseases / Q000378:metabolism / Q000473:pathology*; D014599:Uterus / Q000473:pathology*
D008062:Lipofuscin; D010860:Pigments, Biological