[Effectiveness of a fast neutron beam to induce DNA damage in Ehrlich ascites carcinoma cells irradiated in a aqueous phantom].
The study of damages to DNA molecules of Ehrlich ascites tumor cells exposed in water phantom to fast neutron beam (mean energy of 6 MeV) showed that changes in the extent of DNA injury did not correlate with the absorbed dose distribution at the phantom depth of 8-12 cm, and also that the dose-response function in the phantom was different from that obtained upon irradiation of cells in the air.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000532:radiotherapy*; D004249:DNA Damage; D004273:DNA, Neoplasm / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005214:Fast Neutrons / Q000627:therapeutic use*; D051379:Mice; D008961:Models, Structural; D009502:Neutrons / Q000627:therapeutic use*; D012062:Relative Biological Effectiveness
D004273:DNA, Neoplasm
Izuchenie éffektivnosti puchka bystrykh neĭtronov po povrezhdaemosti DNK kletok astsitnoĭ kartsinomy Erlikha, obluchennykh v vodnom fantome.