title: Systemic necrotizing vasculitis in sickle cell disease.
abstract: A patient with sickle cell disease and systemic necrotizing vasculitis is reported. Although there are a number of immune defects in patients with sickle cell disorders, this association has not been previously reported. We suspect that immunologic disorders frequently are unrecognized in these patients because the symptoms are attributed to complications of sickle cell disease.
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D001327:Autoimmune Diseases / Q000150:complications; D005260:Female; D006801:Humans; D009336:Necrosis; D014657:Vasculitis / Q000150:complications* / Q000473:pathology