Percutaneous organophosphate poisoning.
After cutaneous application of the organophosphate insecticide Diazinon for pubic lice, our patient had symptoms of cholinergic excess, lost consciousness, and had a seizure. Because of the high index of clinical suspicion for potentially lethal organophosphate poisoning, the patient received empiric therapy with pralidoxime and atropine and completely recovered.
D001285:Atropine / Q000627:therapeutic use; D003128:Coma / Q000139:chemically induced*; D003976:Diazinon / Q000008:administration & dosage / Q000506:poisoning*; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D010373:Lice Infestations / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011220:Pralidoxime Compounds / Q000627:therapeutic use; D012640:Seizures / Q000139:chemically induced*; D012651:Self Medication; D012869:Skin Absorption
D007306:Insecticides; D011220:Pralidoxime Compounds; D001285:Atropine; C028797:pralidoxime; D003976:Diazinon