Ouabain and the membrane transport of amino acids and amines.
Evidence is discussed that ouabain has a direct inhibiting effect on the sodium-dependent uptake of amino acids and amines from the extracellular space of the mammalian central nervous system rather than the inhibition being a consequence of raised intracellular sodium levels.
D000588:Amines / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002490:Central Nervous System / Q000378:metabolism*; D010042:Ouabain / Q000494:pharmacology*; D012964:Sodium / Q000494:pharmacology; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D000588:Amines; D000596:Amino Acids; D005680:gamma-Aminobutyric Acid; D010042:Ouabain; D012964:Sodium