A simple method for determination of the factor VII-phospholipid complex using Normotest.
We report here a highly significant positive correlation observed when the factor VII-phospholipid complex (the phospholipase-C sensitive component of factor VII) in plasma was tested in a specific factor VII system and in Normotest (p less than 0.0001). The Normotest system, which is sensitive to variations in coagulation activity within the normal range, was not influenced by phospholipase C when the enzyme was added immediately before the start of the coagulation assay. Normotest is well suited for determination of the factor VII-phospholipid complex in plasma.
D000818:Animals; D001780:Blood Coagulation Tests / Q000379:methods*; D002417:Cattle; D005167:Factor VII / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D010743:Phospholipids / Q000097:blood*; D011247:Pregnancy; D011817:Rabbits; D013925:Thromboplastin / Q000378:metabolism; D010738:Type C Phospholipases / Q000494:pharmacology
D010743:Phospholipids; D005167:Factor VII; D013925:Thromboplastin; D010738:Type C Phospholipases