Urinary C-peptide excretion at onset of insulin dependent diabetes mellitus in children.
The 24-hour urinary excretion of C-peptide and the plasma C-peptide concentration were measured at the onset of insulin dependent diabetes mellitus (IDDM) in children. The excretion of C-peptide was twice as high as that found in normal control subjects, whereas the plasma C-peptide values were markedly lower, indicating increased urinary leakage of C-peptide in this phase of the disease. In the diabetic children under seven years of age the mean value of C-peptide excretion was clearly lower than in the older children.
D000293:Adolescent; D000367:Age Factors; D002096:C-Peptide / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D002940:Circadian Rhythm; D003922:Diabetes Mellitus, Type 1 / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male
D002096:C-Peptide