title: Scanning electron microscopy of the wall of the ovine cervix uteri in relation to tensile strength at parturition.
abstract: There was a progressive loosening of the collagenous fibre bundles in the stroma of the ovine cervix during spontaneous parturition. The change from an organ with predominantly thick collagen fibre bundles to one with a loose network of collagen fibrils was associated in time with a threefold increase in softness as measured by the Stretch modulus. Infusion of oestradiol 17 beta (E2 beta) for 18 hours elicited similar changes in the structure and mechanical properties of the cervix. Infusion of sodium meclofenamate for 18 hours significantly (P less than 0.005) reduced the effect of E2 beta administered simultaneously.
mesh_terms: D000818:Animals; D002584:Cervix Uteri / Q000502:physiology / Q000648:ultrastructure*; D005260:Female; D007743:Labor, Obstetric / Q000502:physiology*; D008855:Microscopy, Electron, Scanning; D011247:Pregnancy; D012756:Sheep / Q000033:anatomy & histology*; D013718:Tensile Strength