[Effect of methyluracil on lipid peroxidation in the plasma and tissue homogenates from ulcer lesions of the gastric wall in rats].
Dynamics of experimental acetate gastric ulcer healing and lipid peroxidation were studied in rat blood and gastric tissues after treatment with methyluracil. The drug was shown to stimulate reparation and to inhibit lipid peroxidation. The antiulcerogenous effects of methyluracil appear to involve the antioxidative mechanisms.
D000818:Animals; D005753:Gastric Mucosa / Q000378:metabolism*; D008054:Lipid Peroxides / Q000097:blood / Q000378:metabolism*; D008163:Luminescent Measurements; D051381:Rats; D013276:Stomach Ulcer / Q000097:blood / Q000188:drug therapy / Q000378:metabolism*; D014498:Uracil / Q000031:analogs & derivatives* / Q000627:therapeutic use
D008054:Lipid Peroxides; D014498:Uracil; C008378:6-methyluracil
Vliianie metiluratsila na perekisnoe okislenie lipidov v plazme krovi i gomogenatakh tkaneĭ iazvennogo defekta stenki zheludka krys.