title: The effect of corneal contact lenses on the oxygen tension in the anterior chamber of the rabbit eye.
abstract: The oxygen tension in the aqueous humor in the anterior chamber of rabbit eyes was measured continuously with a polarographic electrode. The normal oxygen tension in the anterior chamber was 23 +/- 2 mm Hg (mean +/- SD, n = 4). A contact lens was then placed on the cornea for at least 10 min and the drop in oxygen tension recorded. A hard polymethylmethacrylate lens reduced the oxygen tension by 16 +/- 4 mm Hg, and a larger hydroxyethylmethacrylate soft lens (Soflens) decreased oxygen tension by 17 +/- 4 mm Hg (mean +/- SD, n = 4). Comparable statistically significant decreases were seen with the Permalens, Polycon II, and Silcon lenses. Only the elastofilcon A lens (Silsoft) did not decrease the oxygen tension in the anterior chamber significantly.
mesh_terms: D000818:Animals; D000867:Anterior Chamber / Q000502:physiology*; D001082:Aqueous Humor / Q000502:physiology; D003261:Contact Lenses / Q000009:adverse effects; D005128:Eye Diseases / Q000209:etiology; D005260:Female; D008297:Male; D010100:Oxygen / Q000502:physiology*; D010313:Partial Pressure; D011817:Rabbits
chemical_list: D010100:Oxygen