title: [Bacteriological study of acute otitis media in children. Therapeutic consequences].
abstract: One hundred children presenting with acute otitis media underwent a bacteriological study of otitis exudate over a 18 month period. The bacteria found were as follows: Streptococcus pneumoniae (24), Haemophilus influenzae (19), Staphylococcus aureus (12), Streptococcus pyogenes (7), Branhamella catarrhalis (3), and 18 Gram negative bacilli (including 7 Pseudomonas aeruginosa and 11 enterobacteriaceae). One pathogenic bacterium was isolated in 56 cases, 2 or more in 12 cases and none in 32 cases. In the age categories 0-1 year (47 cases) and 1-3 years (31 cases), S. pneumoniae and H. influenzae were the main organisms found, followed by S. pyogenes in children older than 3 years (22 cases). With respect to the antibiotics used for treating otitis, 5/22 S. pneumoniae and 4/17 H. influenzae were erythromycin resistant (9/17 had an intermediate susceptibility) and 7/19 H. influenzae and 1/17 S. pneumoniae were cotrimoxazole resistant. None of the S. pneumoniae and 2/19 H. influenzae were ampicillin resistant. These 2 H. influenzae and 2/3 B. catarrhalis were beta-lactamase producers. They were sensitive to the combination of amoxicillin with clavulanic acid.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000367:Age Factors; D000658:Amoxicillin / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002969:Clavulanic Acids / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010033:Otitis Media / Q000188:drug therapy / Q000382:microbiology*; D010403:Penicillin Resistance
chemical_list: D002969:Clavulanic Acids; D000658:Amoxicillin
vernacular_title: Etude bactériologique des otites moyennes aiguës de l'enfant. Conséquences thérapeutiques.