title: The triose model: glyceraldehyde as a source of energy and monomers for prebiotic condensation reactions.
abstract: Glyceraldehyde acts as a source of energy and monomers in a new model of the origin of life. The simplest form of the model functions by converting formaldehyde from the environment into glyceraldehyde which spontaneously forms hemiacetal adducts that are oxidized to polyglyceric acid. Polyglyceric acid, in turn, acts as an autocatalyst with a rudimentary replicating ability. A unique property of the model is its ability to unite the origin of metabolism and the origin of polymer synthesis into a single process. Furthermore, the chemical resemblance of the model to glycolysis gives it the potential to develop a biological metabolism in a straightforward manner.
mesh_terms: D002151:Calorimetry; D002384:Catalysis; D004735:Energy Transfer; D005557:Formaldehyde; D005985:Glyceraldehyde; D005988:Glyceric Acids; D008954:Models, Biological; D000069497:Origin of Life
chemical_list: D005988:Glyceric Acids; C053491:polyglyceric acid; D005557:Formaldehyde; D005985:Glyceraldehyde