title: A case of first trimester chromosomal mosaicism confined to the cultivation of the gestational products.
abstract: The advantages of the emergence and development of chorionic villi sampling (CVS) for early prenatal diagnosis are evident, but there are a host of new diagnostic problems caused by the use of extraembryonic tissues. We report a case in which 45X/46XY mosaicism was diagnosed by cultivation of chorionic villi and fetal cells. Direct chromosomal preparations of chorionic villi failed to diagnose the abnormality.
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000166:cytology; D002478:Cells, Cultured; D002824:Chorionic Villi / Q000648:ultrastructure*; D002871:Chromosome Banding; D005260:Female; D005333:Fetus / Q000473:pathology; D006059:Gonadal Dysgenesis / Q000175:diagnosis*; D006801:Humans; D009030:Mosaicism; D011247:Pregnancy; D011296:Prenatal Diagnosis