[Antigenicity of the auricular cartilage and its modification by vital preservation. 1. Xenogeneic transplantation of human auricular concha cartilage to the rabbit].
By means of xenotransplantation of human auricular cartilage to rabbits tests were carried out to see, if antigenicity is reduced through storing elastic cartilage either in a nutrient solution (Ham F 12) at 4 degrees C above zero or in a tissue culture (Ham F 12 + 10% serum of a calf-foetus) at 37 degrees C above zero, and if vital preservation prevents degeneration- and resorption processes of cartilage. The results were compared to transplants of fresh, not treated cartilages, and those preserved with cialit and merthiolate. It turned out that these vital preservation methods seem to cause an extensive loss of the cartilages characteristic qualities and that they keep degeneration- and resorption processes at a minimal level. Big differences between storage in nutrient solution and tissue culture could not be observed.
D000818:Animals; D000941:Antigens / Q000276:immunology*; D004425:Ear Cartilage / Q000276:immunology* / Q000637:transplantation / Q000648:ultrastructure; D004431:Ear, External / Q000276:immunology*; D005260:Female; D006085:Graft Survival; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D011817:Rabbits; D013696:Temperature; D014021:Tissue Preservation / Q000379:methods*; D014181:Transplantation Immunology; D014183:Transplantation, Heterologous
D000941:Antigens
Die Antigenität des Ohrknorpels und ihre Beeinflussung durch vitale Konservierung. Teil 1: Xenotransplantation humanen Ohrmuschelknorpels an Kaninchen.