title: Adjuvant radiation therapy in patients upstaged to stage C or D1 disease after radical prostatectomy.
abstract: We administered adjuvant radiation therapy to 56 selected patients with carcinoma of the prostate whose disease was upstaged to stage C or D1 after radical prostatectomy and pelvic lymphadenectomy. The complications associated with radiation therapy were minimal. The local recurrence rate was 2% after mean follow-ups of 67 and 53 months for patients with stage C and D1 disease, respectively. The actuarial 5-year survival rate free of disease was 76% for patients with stage C and 72% with stage D1 a cancer. Further exploration of the role of adjuvant radiation therapy in the treatment of patients with pathological stage C or D1 a disease is warranted.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary; D003131:Combined Modality Therapy; D006801:Humans; D008137:Longitudinal Studies; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery