title: Peripheral blood and bone marrow abnormalities in the acquired immunodeficiency syndrome.
abstract: In reviewing the peripheral hematologic manifestations, bone marrow changes and clinical course in 41 consecutive patients with acquired immunodeficiency syndrome (AIDS), frequent findings included anemia (95%), leukopenia (76%), bone marrow hypercellularity (73%) and pancytopenia (41%). These hematologic abnormalities were not clearly associated with specific clinical manifestations of AIDS, but support the conclusion that the hematopoietic system is a target organ in AIDS. The mechanisms of these abnormalities still need to be evaluated. Clinicians should be aware of these commonly encountered changes.
authors: M
authors: M
authors: Frontiera
authors: A M
authors: AM
authors: Myers
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001855:Bone Marrow Diseases / Q000209:etiology*; D006402:Hematologic Diseases / Q000209:etiology*; D006801:Humans; D007970:Leukopenia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010198:Pancytopenia / Q000209:etiology; D013921:Thrombocytopenia / Q000209:etiology