title: Intralesional methylprednisolone for Langerhans' cell histiocytosis of the orbit and cranium.
abstract: A 27-month-old girl had a rapidly expanding orbital frontal bone mass due to Langerhans' cell histiocytosis. The CT of the orbit showed a lateral orbital mass containing an irregular density that extended into the intracranial cavity through a lytic lesion of the bone. This is the first report of the use in the orbit of an intralesional steroid injection. Five months later the lesion had not recurred. This treatment spared the patient radiation therapy or a craniotomy with curettage.
authors: Department of Ophthalmology, University of Minnesota Hospital, Minneapolis 55455.
authors: J D
authors: JD
authors: Wirtschafter
authors: M
authors: M
authors: Nesbit
authors: P
authors: P
authors: Anderson
authors: K
authors: K
authors: McClain
mesh_terms: D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy; D002675:Child, Preschool; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007267:Injections; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D009916:Orbital Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011859:Radiography; D012886:Skull
chemical_list: D008775:Methylprednisolone