Neurobiological findings in 20 relatively gifted children with Kanner-type autism or Asperger syndrome.
Seventeen children with classical Kanner autism and three children with Asperger syndrome, all of whom had Full-scale IQs above 65, were subjected to a neurobiological assessment, including CAT scan, auditory brainstem response, EEG, chromosomal cultures, cerebrospinal fluid, blood and urine examinations and a thorough physical examination. 15 of the 20 children had 'definite abnormalities' on at least one of these examinations. It is concluded that the number of cases of 'non-organic' autism, even among children with relatively higher intelligence, dwindles rapidly as our neurobiological assessment methods become increasingly sophisticated.
Gillberg
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C
Department of Child and Youth Psychiatry, University of Göteborg, Sweden.
Steffenburg
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Jakobsson
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G
D000293:Adolescent; D001321:Autistic Disorder / Q000503:physiopathology* / Q000523:psychology; D001921:Brain / Q000000981:diagnostic imaging; D002648:Child; D002652:Child Behavior; D002671:Child, Exceptional / Q000523:psychology*; D002675:Child, Preschool; D002875:Chromosomes / Q000032:analysis; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D010455:Peptides / Q000652:urine; D014057:Tomography, X-Ray Computed
D010455:Peptides