title: Behavioral recovery induced by applied electric fields after spinal cord hemisection in guinea pig.
abstract: Applied electric fields were used to promote axonal regeneration in spinal cords of adult guinea pigs. A propriospinal intersegmental reflex (the cutaneous trunci muscle reflex) was used to test lateral tract function after hemisection of the thoracic spinal cord. An electrical field (200 microvolts per millimeter, cathode rostral) applied across the lesion led to functional recovery of the cutaneous trunci muscle reflex in 25 percent of experimental animals, whereas the functional deficit remained in control animals, which were implanted with inactive stimulators.
authors: Center for Paralysis Research, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
authors: R B
authors: RB
authors: Borgens
authors: A R
authors: AR
authors: Blight
authors: M E
authors: ME
authors: McGinnis
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology; D004558:Electric Stimulation; D004560:Electricity; D006168:Guinea Pigs; D009119:Muscle Contraction; D009132:Muscles / Q000294:innervation; D009416:Nerve Regeneration; D010812:Physical Stimulation; D012018:Reflex / Q000502:physiology*; D012867:Skin / Q000294:innervation; D013116:Spinal Cord / Q000502:physiology*