[Effect of anticonvulsants on the psychotropic activity of tranquilizers in their joint use in an experiment].
Effects of anticonvulsants (phenobarbital, hexamidine, benzonal, difenin, chloracon, trimetin, carbamazepine) on the psychotropic activity of tranquillizers (diazepam, chlordiazepoxide, meprotan, trioxazine, mebicar) were studied in experiments on mice and rats. Thirteen combinations were studied by using corazol test, "open field" and elementary-defensive conditioned response technique. According to all three tests the psychotropic activity was enhanced to the greatest degree by administration of hexamidine in combination with chlordiazepoxide.
Zalesov
V S
VS
Kolla
V E
VE
Khvolis
E A
EA
D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects; D004347:Drug Interactions; D004924:Escape Reaction / Q000187:drug effects; D005260:Female; D008297:Male; D008606:Mental Processes / Q000187:drug effects*; D051379:Mice; D009949:Orientation / Q000187:drug effects; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D051381:Rats; D014149:Tranquilizing Agents / Q000494:pharmacology*
D000927:Anticonvulsants; D014149:Tranquilizing Agents; D010433:Pentylenetetrazole
Vliianie antikonvul'santov na psikhotropnuiu aktivnost' trankvilizatorov pri ikh sovmestnom primenenii v éksperimente.