title: Accuracy and reproducibility of the assessment of the global ejection fraction using 195mAu and a single-crystal digital gamma camera: influence of collimator design.
abstract: A sequence of RAO first-pass studies (first with 99mTc and then twice with 195mAu) was performed in 18 normal volunteers and in 12 CAD patients using two different types of collimator for medium energy: a standard collimator (MEMS) and a special high-sensitivity collimator (MEHS). The following data were compared: the peak count rate, the net LV end-diastolic counts and the LVEF. Using MEMS the end-diastolic counts acquired were so low (12% of 99mTc average value) that EF standard deviation had a mean value of 0.061 (range 0.045-0.081). With MEHS the following results were obtained: 1. the peak count rate and LV net end-diastolic counts with 195mAu were 55% and 50% respectively, of 99mTc values; 2. a good correlation was shown between LVEF values either with 99mTc and 195mAu (r = .97), or with 195mAu sequential studies (r = .98).
authors: Nuclear Medicine Department, Istituto di Scienze Mediche Bassini, Italy.
authors: G
authors: G
authors: Zatta
authors: G L
authors: GL
authors: Tarolo
authors: M
authors: M
authors: Gallazzi
authors: A
authors: A
authors: De Agostini
authors: A
authors: A
authors: Albertini
authors: M
authors: M
authors: Radice
authors: D
authors: D
authors: Alberti
mesh_terms: D000328:Adult; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology; D004867:Equipment Design; D005260:Female; D006050:Gold Radioisotopes; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging / Q000295:instrumentation*; D013318:Stroke Volume
chemical_list: D006050:Gold Radioisotopes