[Bone damage of mandibles after radiotherapy of carcinoma of the tongue].
At Osaka University Hospital, the 5-year survival rate for carcinoma of the tongue, treated by radiotherapy, is almost 60% and in early cases, around 80%. However, with this improvement in the survival rate, an increase in the incidence of various complications (xerostomia, soft tissue ulcer, bone damage, etc.) has been observed. Because of these circumstances, a radiographic analysis on the bone damage of the mandibles after radiotherapy was made. Only those patients whose progress had been followed for more than one year and whose disease was well controlled were selected for this study. Early radiographic signs of bone damages showed an enlargement of the periodontal space and a loss of lamina dura. From the results of the study it has been found that bone damage is less common in patients treated by interstitial radiotherapy alone. Bone damage seems to develop more frequently in patients who receive about 30 Gy by external radiotherapy, followed by more than 2,000 mgh. Ra. eq. of interstitial radiotherapy.
Nakamura
M
M
Dept. of Oral Radiology, Niigata Univ. School of Dent.
Kubo
K
K
Furukawa
S
S
Fuchihata
H
H
Shimizutani
K
K
Inoue
T
T
Nishiyama
K
K
Ikeda
H
H
Masaki
N
N
D000368:Aged; D001918:Brachytherapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000528:radiation effects*; D011832:Radiation Injuries / Q000209:etiology* / Q000473:pathology; D011879:Radiotherapy Dosage; D014062:Tongue Neoplasms / Q000473:pathology / Q000532:radiotherapy*