Will treatment with digoxin antibody benefit pregnant patients with toxemia and elevated digoxin like factor?
Some pregnant patients with toxemia, especially those with thrombocytopenia, liver or renal dysfunction have elevated serum DLF (digoxin like factor). Since antidigoxin serum reduces the hypertension of DOCA hypertensive rats, it is proposed that antidigoxin antibodies be tried in the treatment of these select patients with toxemia of pregnancy.
Goodlin
R C
RC
Univ. of Col. Health Sci. Ctr., Denver, CO 80262.
D000906:Antibodies / Q000008:administration & dosage*; D001798:Blood Proteins; D002298:Cardenolides; D004077:Digoxin / Q000037:antagonists & inhibitors* / Q000276:immunology; D005260:Female; D006801:Humans; D008954:Models, Biological; D011225:Pre-Eclampsia / Q000097:blood / Q000628:therapy*; D011247:Pregnancy; D012503:Saponins
D000906:Antibodies; D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D004077:Digoxin