[Effect of sidnocarb on learning and memory].
It has been established that in well-trained rats sydnocarb (mesocarb) does not exert a considerable effect on the generation of conditioned reflex of passive avoidance (CRPA). On the contrary, in poorly-trained animals sydnocarb significantly improves CRPA indexes at all three stages of its generation. Sydnocarb proved most effective, when injected before training (on day I). The absence of sydnocarb-induced pain threshold decrease in response to electrical pain stimulation suggests a direct drug effect on memory processes.
Ganiev
M M
MM
Kharlamov
A N
AN
Raevskiĭ
K S
KS
Guseĭnov
D Ia
DIa
D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects; D004924:Escape Reaction / Q000187:drug effects; D007858:Learning / Q000187:drug effects*; D008297:Male; D008568:Memory / Q000187:drug effects*; D010069:Oxadiazoles / Q000494:pharmacology*; D010146:Pain / Q000503:physiopathology; D011619:Psychotropic Drugs / Q000494:pharmacology*; D051381:Rats; D012054:Reinforcement, Psychology; D012684:Sensory Thresholds / Q000187:drug effects; D013558:Sydnones / Q000494:pharmacology*
D010069:Oxadiazoles; D011619:Psychotropic Drugs; D013558:Sydnones; C009257:sidnocarb
Vliianie sidnokarba na obuchenie i pamiat'.