MR imaging in a case of Hallervorden-Spatz disease.
Magnetic resonance using a 0.5 T system and a T2-weighted spin-echo pulse sequence revealed symmetric areas of marked hypointensity of the globi pallidi in a case with a family history of and presenting with clinical features consistent with Hallervorden-Spatz disease. No such findings were seen in any of 16 normal volunteers of similar age. Magnetic resonance may be useful for diagnosing Hallervorden-Spatz disease.
Tanfani
G
G
Department of Neurology, University of Florence, Italy.
Mascalchi
M
M
Dal Pozzo
G C
GC
Taverni
N
N
Saia
A
A
Trevisan
C
C
D000328:Adult; D001480:Basal Ganglia Diseases / Q000175:diagnosis*; D005917:Globus Pallidus / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000175:diagnosis* / Q000235:genetics