title: Effects of CuCl2 on the dimer-tetramer equilibrium of concanavalin A.
abstract: Tetrameric concanavalin A at neutral pH dissociated into the dimer when CuCl2 was added in a concentration range comparable to protomer concentration. This effect of CuCl2 was largely suppressed when NaCl concentration was increased. Neither the conformation of the protein nor its binding activity to 4-methylumbelliferyl alpha-D-mannopyranoside was affected on addition of CuCl2.
authors: Department of Chemistry, Faculty of Science, Nagoya University, Japan.
authors: H
authors: H
authors: Kanoh
authors: H
authors: H
authors: Maeda
mesh_terms: D003208:Concanavalin A / Q000378:metabolism*; D003300:Copper / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D046911:Macromolecular Substances
chemical_list: D046911:Macromolecular Substances; D003208:Concanavalin A; D003300:Copper; C029892:cupric chloride