[Monotherapy of epileptic children with monitoring of the serum levels of anticonvulsive drugs].
In 46 children with partial and primarily generalized seizures monotherapy was started with amizepine, luminal, mysodin or phenytoin. The treatment was monitored determining serum concentrations of the drugs. Monotherapy was effective in 74% of cases. In 89% of them the duration of treatment was one year, at least. In some children the values of amizepine, luminal and mysodin concentrations below the therapeutic level were effective. The evolution of electroencephalographic changes failed to correspond strictly to the clinical results of the treatment.
Kaciński
M
M
Z II Kliniki Chorób Dzieci Instytutu Pediatrii AM w Krakowie.
Hyla
B
B
Nowak
J
J
Szafran
Z
Z
Garapich
M
M
Jaśkiewicz
T
T
D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage* / Q000097:blood; D002648:Child; D002675:Child, Preschool; D004351:Drug Resistance; D004827:Epilepsy / Q000188:drug therapy*; D006801:Humans; D008991:Monitoring, Physiologic
D000927:Anticonvulsants
Monoterapia u dzieci chorych na padaczke z wykorzystaniem monitorowania stezeń leków przeciwpadaczkowych w surowicy krwi.