title: Deep venous thrombophlebitis: detection with 4-hour versus 24-hour platelet scintigraphy.
abstract: Thirty-one nonheparinized patients with suspected deep venous thrombophlebitis (DVT) underwent contrast venography and indium-111 platelet scintigraphy (In-111 PS). Venography permitted identification of acute DVT in 12 of 31 cases (39%). One additional patient was considered to have acute DVT despite nonconclusive venography results. In-111 PS results were positive at 4 hours in nine of 13 cases (69%) and at 24 hours in 12 of 13 cases (92%). Two of four patients with false-negative 4-hour In-111 PS studies had received warfarin. Thus, the sensitivity of 4-hour In-111 PS in patients not receiving anticoagulants was 82%. Venography results were negative for acute DVT in 18 cases, and 4-hour In-111 PS studies were negative or equivocal in each. In-111 PS is an alternative to contrast venography for detecting acute DVT. If 4-hour In-111 PS results are positive, anticoagulation can be initiated. Delayed images are necessary if the 4-hour images are negative or equivocal.
authors: Department of Radiology, University of Iowa Hospitals, Iowa City 52242.
authors: J E
authors: JE
authors: Seabold
authors: G R
authors: GR
authors: Conrad
authors: J A
authors: JA
authors: Ponto
authors: D A
authors: DA
authors: Kimball
authors: E E
authors: EE
authors: Frey
authors: F
authors: F
authors: Ahmed
authors: J D
authors: JD
authors: Coughlan
authors: K C
authors: KC
authors: Jensen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001132:Arm; D001792:Blood Platelets; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D011877:Radionuclide Imaging; D013924:Thrombophlebitis / Q000000981:diagnostic imaging*; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D007205:Indium Radioisotopes; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; C027278:urovision