title: Effects of short- and long-term feeding of zinc oxide-supplemented diets on the mature, female domestic fowl with special reference to tissue mineral content.
abstract: 1. In Expt 1, the effects on laying hens of diets supplemented with zinc oxide providing up to 20 g added zinc/kg were compared. In Expt 2 the diets contained up to 6 g added Zn/kg. 2. In both experiments, food intake, body-weight, egg number, and liver, oviduct and ovary weights/kg body-weight were significantly reduced by added ZnO; gizzard weight/kg body-weight was significantly increased. In Expt 2, pancreas weight was significantly reduced by added ZnO. 3. Liver, kidney and pancreatic Zn and iron concentrations were significantly elevated in both experiments. 4. In both experiments, liver, kidneys and pancreatic copper concentrations gave quadratic responses to added ZnO.
authors: Agricultural and Food Chemistry Research Division, Department of Agriculture for Northern Ireland, Belfast.
authors: N
authors: N
authors: Jackson
authors: S W
authors: SW
authors: Gibson
authors: M H
authors: MH
authors: Stevenson
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D003300:Copper / Q000493:pharmacokinetics*; D004435:Eating / Q000187:drug effects; D004531:Eggs; D005260:Female; D005527:Food, Fortified; D007501:Iron / Q000493:pharmacokinetics*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D010179:Pancreas / Q000378:metabolism; D011200:Poultry / Q000378:metabolism*; D013997:Time Factors; D015032:Zinc / Q000493:pharmacokinetics* / Q000494:pharmacology*; D015034:Zinc Oxide / Q000494:pharmacology*
chemical_list: D003300:Copper; D007501:Iron; D015032:Zinc; D015034:Zinc Oxide