Diagnostic assessment of diabetic microangiopathy by tcPO2 stimulation tests.
Transcutaneous PO2 measurements at 37 degrees C can recognize and quantify diabetic microangiopathy if suitable stimulation tests are used. The following parameters are of practical importance: resting PO2, postocclusive PO2, rubefacient-induced PO2 and 45 degrees C heating PO2. Patients with diabetic microangiopathy show diminished PO2 values in rubefacient-induced PO2 and 45 degrees C heating PO2. The former ist probably related to endothelial-cell function disturbances and the letter to organic vessel wall changes. Thus, a quantitative and differentiated picture of microangiopathy can be obtained in each individual patient.
Weindorf
N
N
Department of Dermatology, St. Josef-Hospital, Ruhr-University Bochum.
Schultz-Ehrenburg
U
U
Altmeyer
P
P
D000328:Adult; D000368:Aged; D001785:Blood Gas Monitoring, Transcutaneous; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis; D003925:Diabetic Angiopathies / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D012881:Skin Temperature