title: Effects of cigarette smoking on the location, healing and recurrence of gastric ulcers.
abstract: The effects of cigarette smoking on the location, healing and recurrence of gastric ulcers were investigated by endoscopy. The endoscopic Congo red test developed in this clinic revealed a close relationship between the location of gastric ulcers and the extent of the acid-secreting area, and the smoking index. In general, in patients with a high smoking index, gastric ulcers were located proximally and the acid-secreting area was small. These findings indicate that smoking is associated with the development of fundal gastritis and also with the development of high-lying ulcers. Healing of gastric ulcers was significantly faster, and their recurrence was significantly less frequent in patients who stopped smoking or reduced smoking by a half or more after treatment, than in those who did not.
authors: Department of Gastrointestinal Oncology, Center for Adult Diseases, Osaka.
authors: M
authors: M
authors: Tatsuta
authors: H
authors: H
authors: Iishi
authors: S
authors: S
authors: Okuda
mesh_terms: D005260:Female; D005744:Gastric Acid / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism / Q000473:pathology; D005773:Gastroscopy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012907:Smoking / Q000009:adverse effects*; D013270:Stomach / Q000473:pathology*; D013276:Stomach Ulcer / Q000209:etiology / Q000473:pathology*