[Modifying effect of nutrition on the mutagenic activity of phosphorus and fluorine compounds].
The test animals were fed with low-grade food during 2-5 months under conditions of acute and chronic action of hydrogen phosphide and hydrogen fluoride induced by inhalation, that resulted in the pronounced impairment of the chromosomal apparatus of the bone marrow cells in the rats. A principal possibility has been established of modification of the hydrogen phosphide and hydrogen fluoride cytogenetic effect by the alimentary action. In particular, it has been found that the effect is significantly higher when the rats are fed with a low-grade ration than under conditions of balanced nutrition.
Tazhibaev
Sh S
ShS
Kozhakhmetova
E B
EB
Aldabergenova
K U
KU
Mamyrbaev
A A
AA
D000818:Animals; D001853:Bone Marrow / Q000648:ultrastructure; D002869:Chromosome Aberrations / Q000187:drug effects; D004032:Diet; D005461:Fluorine / Q000633:toxicity*; D009152:Mutagenicity Tests; D009153:Mutagens; D010758:Phosphorus / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains
D009153:Mutagens; D010758:Phosphorus; D005461:Fluorine
Modifitsiruiushchee vliianie pitaniia na mutagennyĭ éffekt soedineniĭ fosfora i ftora.