Circadian profiles and circaseptan periodicity in the frequency of administration of analgetic drugs after oral surgery.
The frequencies of 5706 demands for analgetic drugs after dental operations have been recorded. The highest consumption of analgetics is observed around postoperative day 7. On days 2 and 3, the circadian course of the frequencies peaks in the early morning (around 06.00). On days 6 and 7 the frequencies of analgetic administrations increase during the evening (around 18.00-20.00). The circadian profiles of frequencies therefore exhibit a phase jump of about 180 degrees during the postoperative period, indicating a change of dominance from a more protopathic type of pain to an epicritic one.
Pöllmann
L
L
Institut für Arbeitsphysiologie und Rehabilitationsforschung Philipps-Universität Marburg, Federal Republic of Germany.
Hildebrandt
G
G
D000082:Acetaminophen / Q000008:administration & dosage*; D000328:Adult; D002940:Circadian Rhythm; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D010149:Postoperative Pain / Q000188:drug therapy*
D000082:Acetaminophen