title: [Mid-systolic ejection murmur with thrill caused by right ventricular outflow tract obstruction secondary to septal aneurysm following myocardial infarction: a case report].
abstract: A 71-year-old woman with a history of previous myocardial infarction was transferred to our hospital for evaluation of chest pain and ventricular tachycardia. On admission, a loud mid-systolic ejection murmur accompanied by a thrill was found at the left sternal border in the third intercostal space, and it was significantly accentuated in the post-extrasystolic beat. Abnormal Q waves and ST elevations were noted in leads I, aVL and V5,6 on electrocardiograms. Echocardiograms, confirmed a septal-to-apical aneurysm, and a thin interventricular septum (IVS) with paradoxical motion. Right ventricular (RV) catheterization showed a pressure gradient of 21 mmHg between the outflow tract (RVOT) and the apex, and a mid-systolic ejection murmur was recorded in the RVOT on an intracardiac phonocardiogram. Coronary arteriograms revealed total occlusion of the left anterior descending artery in its proximal portion, and a 90% stenosis of the circumflex artery. A left ventriculogram demonstrated a septal-to-apical aneurysm with a markedly reduced ejection fraction of 0.16. A right ventriculogram showed obstruction to RVOT caused by systolic ballooning of the IVS. In this patient, the mid-systolic ejection murmur was probably caused by the obstruction of the outflow tract secondary to septal aneurysm following old myocardial infarction.
authors: Department of Medicine, Kawasaki Medical School, Okayama.
authors: K
authors: K
authors: Hasegawa
authors: S
authors: S
authors: Kakumae
authors: T
authors: T
authors: Sawayama
authors: S
authors: S
authors: Nezuo
authors: Y
authors: Y
authors: Harada
authors: M
authors: M
authors: Samukawa
authors: T
authors: T
authors: Fujiwara
authors: M
authors: M
authors: Yoneda
authors: M
authors: M
authors: Nakao
mesh_terms: D000368:Aged; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006322:Heart Aneurysm / Q000150:complications*; D006326:Heart Auscultation; D006331:Heart Diseases / Q000209:etiology* / Q000503:physiopathology; D006337:Heart Murmurs; D006346:Heart Septum; D006352:Heart Ventricles; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications*; D010701:Phonocardiography