Neuroendocrine carcinoma of the parotid gland: a report of two cases with ultrastructural and immunohistochemical studies.
Two cases of primary small cell carcinoma of the parotid gland are reported. This rare neoplasm usually presents as a painful or painless mass in the gland. The finding of neurosecretory granules by electron microscopic study, combined with strong immunoreactivity for neuron-specific enolase and chromogranin, confirms the true neuroendocrine origin of the carcinoma. This tumor appears to have a better prognosis than small cell carcinoma of the lung, which it resembles histologically.
Huntrakoon
M
M
Department of Pathology and Oncology, University of Kansas Medical Center, Kansas City.
D000368:Aged; D002277:Carcinoma / Q000276:immunology / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000276:immunology / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure