title: Serum myoglobin in patients on intermittent and continuous ambulatory peritoneal dialysis.
abstract: Serum myoglobin levels were determined in patients maintained on chronic peritoneal dialysis. Eleven intermittent peritoneal dialysis patients had a mean serum myoglobin of 174 +/- 29 ng/ml. In 7 patients tested serially, there was no consistent change in serum myoglobin: the mean level was 154 +/- 36 ng/ml pre-dialysis and 170 +/- 20 ng/ml post-dialysis. Seventeen patients on continuous ambulatory peritoneal dialysis had a mean serum myoglobin of 215 +/- 18 ng/ml. Two patients given oral carnitine supplements had a substantial decrease in their serum myoglobin levels. Patients on peritoneal dialysis, like those on hemodialysis, tend to have elevated serum myoglobin levels, and neither form of dialysis affects serum myoglobin concentration. This hypermyoglobinemia may be due to metabolic changes in muscle.
authors: Department of Medicine, Harlem Hospital Center, Columbia University College of Physicians & Surgeons, New York, NY.
authors: D A
authors: DA
authors: Feinfeld
authors: C
authors: C
authors: Verger
authors: A M
authors: AM
authors: Briscoe
authors: J L
authors: JL
authors: Hotchkiss
authors: H M
authors: HM
authors: Nurse
authors: F
authors: F
authors: Merlin
authors: S
authors: S
authors: Nair
authors: P M
authors: PM
authors: Hart
mesh_terms: D000328:Adult; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D009211:Myoglobin / Q000378:metabolism*; D010530:Peritoneal Dialysis; D010531:Peritoneal Dialysis, Continuous Ambulatory
chemical_list: D009211:Myoglobin