title: Histological classification of spermatic cord cysts in relation to their histogenesis.
abstract: Light microscopy study of spermatic cord cysts in 26 men revealed three different histological patterns. First, cysts of probable mesothelial origin (14 cases) with an unilocular aspect: their epithelial cells showed poor cohesion and often appeared sloughed; subepithelial hyalinization or fibrin deposits were frequent. Second, cysts of probable embryonal (mesonephric) origin (8 cases): they were usually multilocular cysts and their epithelial cells showed great cohesion: zones of ciliated columnar epithelium associated with embryonal remnants displaying a similar epithelium were often found; the embryonal remnants and the cyst lumen contained spermatozoa in 2 cases. Third, cysts of doubtful origin (4 cases) showing abundant inflammatory infiltrates, which had destroyed the epithelium; the unilocular pattern observed in 3 cases suggests a mesothelial origin for these cysts, while the multilocular pattern and presence of embryonal remnants in the other case suggest an embryonal origin.
authors: Department of Morphology, School of Medicine, Autonomous University of Madrid, Spain.
authors: M
authors: M
authors: Nistal
authors: L
authors: L
authors: Iniguez
authors: R
authors: R
authors: Paniagua
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003560:Cysts / Q000145:classification / Q000196:embryology / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D005832:Genital Diseases, Male / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D013085:Spermatic Cord / Q000196:embryology / Q000473:pathology*