Monitoring the progression of renal failure in a horse with polycystic kidney disease: use of the reciprocal of serum creatinine concentration and sodium sulfanilate clearance half-time.
Sequential reciprocals of serum creatinine concentration and sodium sulfanilate clearance half-times were used to monitor a horse with chronic renal failure. The horse was diagnosed as having polycystic kidney disease; at least one cyst was of distal tubular origin. Using the plots of the sequential data, a reasonably accurate prediction was made for complete renal decompensation to develop.
Bertone
J J
JJ
Department of Clinical Sciences, College of Veterinary Medicine, Colorado State University, Fort Collins 80523.
Traub-Dargatz
J L
JL
Fettman
M J
MJ
Wilke
L
L
Wrigley
R H
RH
Jaenke
R
R
Paulsen
M E
ME
D000818:Animals; D001557:Benzenesulfonates; D003404:Creatinine / Q000097:blood*; D005919:Glomerular Filtration Rate; D006207:Half-Life; D006734:Horse Diseases / Q000175:diagnosis* / Q000209:etiology; D006736:Horses; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D008297:Male; D007690:Polycystic Kidney Diseases / Q000150:complications / Q000662:veterinary*; D013425:Sulfanilic Acids / Q000493:pharmacokinetics
D001557:Benzenesulfonates; D013425:Sulfanilic Acids; D003404:Creatinine