Anti-Bacteroides fragilis substance from rhubarb.
Extracts of 178 Chinese herbs were screened for their antibacterial activity against Bacteroides fragilis a major anaerobic microorganism in the intestinal flora of humans. Only rhubarb root (Rheum officinale) was found to have significant activity and the purified active substance was identified as rhein.
Cyong
J
J
Oriental Medicine Research Center, Kitasato Institute, Tokyo, Japan.
Matsumoto
T
T
Arakawa
K
K
Kiyohara
H
H
Yamada
H
H
Otsuka
Y
Y
D000880:Anthraquinones / Q000032:analysis / Q000494:pharmacology; D001441:Bacteroides fragilis / Q000187:drug effects*; D008518:Medicine, East Asian Traditional; D008826:Microbial Sensitivity Tests; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000032:analysis*; D012250:Rheum / Q000032:analysis*
D000880:Anthraquinones; D010936:Plant Extracts; C020491:rhein