title: Measurement of pleural pressure at low and high frequencies in normal rabbits.
abstract: In eight tracheotomized adult rabbits placed in the supine position, we employed a catheter-tip piezoresistive pressure transducer to measure esophageal pressure (Pes) and assessed the validity of taking the changes in Pes to be the changes in pleural pressure (Ppl). We applied an occlusion test in which the tracheal cannula was occluded during either spontaneous inspiratory efforts or body surface oscillations ranging from 3 to 50 Hz. The relationship between Pes and airway opening pressure (Pao) was recorded. In all instances, the changes in Pes and Pao were virtually identical in both amplitude and phase. We conclude that, as evaluated by the occlusion test, a catheter-tip pressure transducer placed in the esophagus of rabbits can give adequate estimation of local pleural changes up to at least 50 Hz.
authors: Department of Biomedical Engineering, University of Southern California, Los Angeles 90089.
authors: D A
authors: DA
authors: Chartrand
authors: T H
authors: TH
authors: Ye
authors: J M
authors: JM
authors: Maarek
authors: H K
authors: HK
authors: Chang
mesh_terms: D000818:Animals; D002404:Catheterization; D004947:Esophagus / Q000502:physiology*; D008168:Lung / Q000502:physiology*; D009991:Oscillometry; D010994:Pleura / Q000502:physiology*; D011312:Pressure; D011817:Rabbits