[Pilot clinical study on the use of a new nonsteroid anti-inflammatory drug (flunoxaprofen) in arthrosis pathology].
Twenty-five patients (10 males and 15 females, mean age 56.5 years) suffering from osteoarthritis were admitted to a clinical trial in order to evaluate the efficacy and long-term tolerability of Flunoxaprofen, a new non-steroidal anti-inflammatory compound. Flunoxaprofen 100 mg was given orally twice a day to the patients for a 60 days period. The variables involving the clinical effectiveness of Flunoxaprofen, especially pain and joint motion range, assessed every two weeks showed a considerable and progressive improvement of the symptoms all along the period of treatment. Blood chemistry, hematology and urinalysis, performed routinely on every patient concurrently with their pre-treatment and subsequent clinical assessments, showed the remarkable tolerability of the drug.
Trombaccia
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Divisione di Ortopedia e Traumatologia, Nuova I.T.O.R., Roma U.S.L. 5.
Papalia
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Di Castro
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A
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001583:Benzoxazoles / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D010865:Pilot Projects
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001583:Benzoxazoles; C045356:flunoxaprofen
Studio clinico pilota sull'uso di un nuovo farmaco antiinfiammatorio non steroideo (flunoxaprofene) nella patologia artrosica.