Leakage from egg phosphatidylcholine vesicles induced by Ca2+ and alcohols.
The results shown in this paper indicate that the permeability properties of egg yolk phosphatidylcholine sonicated vesicles as detected by the leakage of carboxy fluorescein changes according to the Ca2+ content. Vesicles containing Ca2+ show a higher rate of leakage than those containing Na+ solutions in response to the increase of Ca2+ concentration in the outer solution. The results are interpreted in terms of the rigidity promoted by Ca2+ and are compared to those obtained with long and short chain alcohols.
Disalvo
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Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas, Facultad de Ciencias Exactas, UNLP, La Plata, Argentina.
D002118:Calcium / Q000494:pharmacology*; D004530:Egg Yolk; D005233:Fatty Alcohols / Q000494:pharmacology*; D005452:Fluoresceins; D008560:Membrane Fluidity; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; D012964:Sodium / Q000494:pharmacology; D013696:Temperature
D005233:Fatty Alcohols; D005452:Fluoresceins; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; C024098:6-carboxyfluorescein; C005031:cetyl alcohol; D012964:Sodium; D002118:Calcium