A single half-turnover of the glucose carrier of the human erythrocyte.
Single half-turnovers of the glucose carrier of the human erythrocyte have been measured by recruiting carriers to the outward-facing conformation by (a) pre-exposing cells to extracellular maltose, or (b) pre-warming cells to 38 degrees C, before addition of D-[14C]glucose at 0 degrees C. Based on these experiments estimates of the number of glucose carriers per red cell range from 124,000 to 190,000.
Lowe
A G
AG
Department of Biochemistry and Molecular Biology, Medical School, University of Manchester, U.K.
Walmsley
A R
AR
D001786:Blood Glucose / Q000378:metabolism; D004912:Erythrocytes / Q000032:analysis / Q000378:metabolism*; D006358:Hot Temperature; D006801:Humans; D007700:Kinetics; D008320:Maltose / Q000494:pharmacology; D009004:Monosaccharide Transport Proteins / Q000097:blood*; D011487:Protein Conformation / Q000187:drug effects
D001786:Blood Glucose; D009004:Monosaccharide Transport Proteins; D008320:Maltose