title: Reversible capsulo-tegmental locked-in state as first manifestation of multiple sclerosis.
abstract: An 18-year-old girl developed a reversible locked-in state with bilateral ptosis and almost complete ophthalmoplegia. She later presented with a relapsing and remitting course suggestive of multiple sclerosis. Autopsy findings demonstrated bilateral capsular and tegmental demyelinating lesions. In addition to this unusual aetiology, this is the first report with pathological evidence of a locked-in syndrome due to lesions outside the ventral brainstem.
authors: Department of Neurology, Erasme University Hospital, Brussels, Belgium.
authors: P A
authors: PA
authors: Seeldrayers
authors: S
authors: S
authors: Borenstein
authors: J M
authors: JM
authors: Gerard
authors: J
authors: J
authors: Flament-Durand
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology; D009886:Ophthalmoplegia / Q000209:etiology* / Q000503:physiopathology; D011782:Quadriplegia / Q000209:etiology*