[Change in the functional indices of animals during prolonged inhalation of acetic acid].
Laboratory animals inhaled acetic acid vapors at a concentration of 86 to 27 mg/m3 for 3 to 35 days. It was found that the dose 36 mg/m3 inhaled for as long as 22 days constituted the minimal acting dose. The most sensitive parameters to be used in detecting the toxic effect of acetic acid were: treadmill run duration, open field activity, and ethylene, acetaldehyde and acetone concentrations in the exhaled air.
Savina
V P
VP
Anisimov
B V
BV
D000079:Acetaldehyde / Q000032:analysis; D000085:Acetates / Q000008:administration & dosage / Q000633:toxicity*; D019342:Acetic Acid; D000096:Acetone / Q000032:analysis; D000280:Administration, Inhalation; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D005030:Ethylenes / Q000032:analysis; D008297:Male; D051379:Mice; D051381:Rats; D012119:Respiration; D013997:Time Factors
D000085:Acetates; D005030:Ethylenes; D000096:Acetone; C036216:ethylene; D000079:Acetaldehyde; D019342:Acetic Acid
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