title: Role of antibiotic prophylaxis in surgery for nonperforated appendicitis.
abstract: This report examines the efficacy of preoperative antibiotics in cases of nonperforated appendicitis. The charts of 61 patients who had an operative and pathologic diagnosis of acute nonperforated appendicitis were reviewed. Thirty-one patients received preoperative cephalosporins, and in one patient (3.2%) a subsequent wound infection developed. Of 30 patients who did not receive preoperative antibiotics, four (13.2%) patients developed septic complications. The difference in postoperative septic complications between these groups is not statistically significant (P = .3310). Preoperative prophylaxis with cephalosporins in cases of nonperforated appendicitis is not indicated.
authors: Department of Surgery, UMDNJ-New Jersey Medical School, Newark.
authors: R J
authors: RJ
authors: Coleman
authors: J M
authors: JM
authors: Blackwood
authors: K G
authors: KG
authors: Swan
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001064:Appendicitis / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents