title: Classification of rheumatoid arthritis: the importance of including data from the siblings.
abstract: A discriminant analysis has been applied to physical and laboratory data on a series of 37 patients with rheumatoid arthritis (RA). Good discrimination was found between RA when it was associated with organ-specific autoimmune phenomena and when it was not. When data from other members of the families was included there was consistently better discrimination than when using data from the patients alone. The results suggest that future studies of classification of variable diseases should include study of relatives.
authors: Department of Rheumatology, University of Newcastle-upon-Tyne, England.
authors: D J
authors: DJ
authors: Walker
authors: A M
authors: AM
authors: Stephenson
authors: I D
authors: ID
authors: Griffiths
authors: D F
authors: DF
authors: Roberts
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000145:classification* / Q000235:genetics / Q000276:immunology; D001323:Autoantibodies / Q000302:isolation & purification; D001327:Autoimmune Diseases / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009928:Organ Specificity; D013959:Thyroid Diseases / Q000145:classification / Q000235:genetics / Q000276:immunology
chemical_list: D001323:Autoantibodies