Localization of the oncogene c-erbA2 to human chromosome 3.
The human c-erbA1 gene has been previously mapped to chromosome 17. We have now mapped c-erbA2 to the short arm of chromosome 3, using a human genomic probe in Southern analysis of DNA from a panel of human/mouse somatic cell hybrids. In situ hybridization using the same probe on metaphase chromosomes has enabled fine chromosome mapping of c-erbA2 to the chromosome region 3p21-pter.
Rider
S H
SH
Imperial Cancer Research Fund, Lincoln's Inn Fields, London.
Gorman
P A
PA
Shipley
J M
JM
Moore
G
G
Vennstrom
B
B
Solomon
E
E
Sheer
D
D
D000818:Animals; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3 / Q000166:cytology; D004247:DNA; D006801:Humans; D006822:Hybrid Cells; D008677:Metaphase; D009693:Nucleic Acid Hybridization; D009857:Oncogenes
D004247:DNA