Influence of thiamin supplements on furazolidone-induced cardiomyopathy in turkey poults.
Furazolidone (700 ppm) was fed to turkey poults from 2 to 5 weeks of age. The drug produced a cardiomyopathy and reduced the feed intake and growth of the birds. Thiamin was concurrently injected into the furazolidone-fed poults to determine whether the vitamin would prevent or reduce the severity of the cardiotoxic effect of the drug. Supplemental injections of thiamin had no significant effect on feed consumption or growth of the birds nor did they protect the heart against the cardiotoxicity. The conclusion is that furazolidone-induced cardiomyopathy is not caused by a thiamin deficiency.
Czarnecki
C M
CM
Department of Veterinary Biology, College of Veterinary Medicine, University of Minnesota, St. Paul 55108.
Ali
B H
BH
D000818:Animals; D001835:Body Weight; D009202:Cardiomyopathies / Q000139:chemically induced / Q000188:drug therapy / Q000662:veterinary*; D004435:Eating; D004562:Electrocardiography / Q000662:veterinary; D005664:Furazolidone / Q000009:adverse effects*; D011201:Poultry Diseases / Q000139:chemically induced / Q000188:drug therapy*; D013831:Thiamine / Q000627:therapeutic use*; D013832:Thiamine Deficiency / Q000139:chemically induced / Q000662:veterinary; D014422:Turkeys
D005664:Furazolidone; D013831:Thiamine