Deep venous thrombophlebitis: detection with 4-hour versus 24-hour platelet scintigraphy.
Thirty-one nonheparinized patients with suspected deep venous thrombophlebitis (DVT) underwent contrast venography and indium-111 platelet scintigraphy (In-111 PS). Venography permitted identification of acute DVT in 12 of 31 cases (39%). One additional patient was considered to have acute DVT despite nonconclusive venography results. In-111 PS results were positive at 4 hours in nine of 13 cases (69%) and at 24 hours in 12 of 13 cases (92%). Two of four patients with false-negative 4-hour In-111 PS studies had received warfarin. Thus, the sensitivity of 4-hour In-111 PS in patients not receiving anticoagulants was 82%. Venography results were negative for acute DVT in 18 cases, and 4-hour In-111 PS studies were negative or equivocal in each. In-111 PS is an alternative to contrast venography for detecting acute DVT. If 4-hour In-111 PS results are positive, anticoagulation can be initiated. Delayed images are necessary if the 4-hour images are negative or equivocal.
Seabold
J E
JE
Department of Radiology, University of Iowa Hospitals, Iowa City 52242.
Conrad
G R
GR
Ponto
J A
JA
Kimball
D A
DA
Frey
E E
EE
Ahmed
F
F
Coughlan
J D
JD
Jensen
K C
KC
D000368:Aged; D000369:Aged, 80 and over; D001132:Arm; D001792:Blood Platelets; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D011877:Radionuclide Imaging; D013924:Thrombophlebitis / Q000000981:diagnostic imaging*; D013997:Time Factors
D004338:Drug Combinations; D007205:Indium Radioisotopes; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; C027278:urovision