Spectral resolution in clinical magnetic resonance spectroscopy.
We observe linewidths of 0.1-0.4 ppm in 31P spectra of human muscle, liver, and brain. T2 measurements of muscle phosphocreatine, together with previous brain studies, indicate that further improvements in linewidth to 0.02-0.05 ppm might often be achieved, but in some lesions magnetic susceptibility variations may limit spectral resolution.
Cox
I J
IJ
NMR Unit, Hammersmith Hospital, London, England.
Bryant
D J
DJ
Ross
B D
BD
Young
I R
IR
Gadian
D G
DG
Bydder
G M
GM
Williams
S R
SR
Busza
A L
AL
Bates
T E
TE
D001921:Brain / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D009132:Muscles / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism*
D010725:Phosphocreatine