Alkaline phosphatase activity in peripheral nerves and endothelial cell cultures in leprosy.
Alkaline phosphatase activity in leprosy nerves was studied. The activity was mainly in blood vessels and was maximum in healthy nerves. Low levels were seen in crush injury. In leprosy lower levels were in BT than LL cases. Endothelial cells (in vitro) released alkpase when infected with live bacilli only. No response was observed with heat killed bacilli.
Mehta
L
L
Department of Anatomy, Grant Medical College, Bombay.
Dorvadi
M H
MH
Damavandi
N M
NM
D000293:Adolescent; D000328:Adult; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D002478:Cells, Cultured; D002648:Child; D004730:Endothelium, Vascular / Q000201:enzymology*; D006801:Humans; D007918:Leprosy / Q000201:enzymology*; D008297:Male; D051379:Mice; D008875:Middle Aged; D010525:Peripheral Nerves / Q000201:enzymology*; D011826:Radial Nerve / Q000201:enzymology; D012584:Sciatic Nerve / Q000201:enzymology; D014471:Umbilical Veins / Q000201:enzymology
D000469:Alkaline Phosphatase