Infantile fibrosarcoma of femur.
We describe the clinical presentation and pathological features of an infantile fibrosarcoma of the femur that occurred in a 3 1/2-month-old male infant. The tumor grew rapidly, reaching large size within a few months, finally requiring amputation. The tumor was poorly circumscribed, infiltrating the adjacent soft tissue extensively. Microscopically, it was a highly cellular tumor composed of immature-appearing spindle-shaped cells. Ultrastructural study revealed mesenchymal cells with fibroblastic and histiocytic differentiation.
Bernadó
L
L
Department of Pathology, Hospital Infantil Vall d'Hebrón, Barcelona, Spain.
Admella
C
C
Lucaya
J
J
Sanchez de Toledo
J
J
Bosch
J
J
D001859:Bone Neoplasms / Q000473:pathology*; D005269:Femur / Q000473:pathology*; D005354:Fibrosarcoma / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D006651:Histocytochemistry; D006801:Humans; D007223:Infant; D008297:Male; D008854:Microscopy, Electron