The use of psychophysical, structural, and electrodiagnostic parameters to identify glaucomatous damage.
Fifty-one patients with early glaucoma and 29 patients without the disease had their contrast sensitivity, colour vision, differential light threshold, neuroretinal rim area, retinal nerve fibre layer, pattern-reversal electrogram and visually evoked potential examined. A stepwise discriminant analysis found that the combination of the vertical cup disc ratio, the diffuse nerve fibre layer score and the localized nerve fibre layer score correctly identified 98% of the normals and 84% of the glaucoma patients. Single parameters and various combinations of parameters were also examined for their ability to discriminate between the two groups. Fifty-two glaucoma suspects were similarly examined and were classified into those whose discriminant functions were normal or abnormal.
Drance
S M
SM
Department of Ophthalmology, University of British Columbia, Vancouver, Canada.
Airaksinen
P J
PJ
Price
M
M
Schulzer
M
M
Douglas
G R
GR
Tansley
B
B
D004568:Electrodiagnosis; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005901:Glaucoma / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D009412:Nerve Fibers / Q000473:pathology; D011601:Psychophysics / Q000379:methods*; D011930:Reaction Time; D012016:Reference Values; D012160:Retina / Q000473:pathology; D013223:Statistics as Topic