Effects of stellate ganglionectomy on the cat cardiovascular function.
The effects of stellate ganglionectomy on cardiovascular function were assessed in pentobarbital-anesthetized cats. A right stellectomy produced much more profound bradycardiac effects than a left stellectomy. This finding demonstrated that the stellate ganglion exerted a lateralized influence on heart beat in the cat. The cardiovascular response of intact cats to phase 4 (overshoot) of the Valsalva-like maneuver (VM) was reflex bradycardia. In response to VM, however, reflex bradycardia was completely abolished by a right or bilateral stellectomy, or by pretreatment with propranolol, but not by a left stellectomy alone or with phentolamine. The data indicated that the right stellate ganglion in cats makes a major contribution to cardiovascular control, especially over reflex bradycardia mechanisms.
Chuang
K S
KS
Department of Surgery, National Defense Medical Center, Taipei, Taiwan, Republic of China.
Shih
C J
CJ
Liu
J C
JC
Wang
S D
SD
Lin
M T
MT
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D001919:Bradycardia / Q000209:etiology; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000503:physiopathology; D002415:Cats; D003971:Diastole; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D008297:Male; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D012018:Reflex; D013233:Stellate Ganglion / Q000502:physiology*; D013599:Systole
D011433:Propranolol; D010646:Phentolamine