Influence of a growing ascitic tumor in mice on the distribution of injected 65Zn: role of the quantity of zinc administered.
65-Zinc distribution was studied in different organs of either healthy mice or mice bearing an ascitic tumor. This study clearly showed that zinc distribution differs between healthy and tumoral mice. Moreover, zinc distribution in the different organs of the mice is modified by the quantity administered.
Joseph
A
A
Institut Curie, Section de Physique et Chimie, Paris, France.
Apelgot
S
S
Guille
E
E
D000818:Animals; D001201:Ascites / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D051379:Mice; D009374:Neoplasms, Experimental / Q000378:metabolism*; D014018:Tissue Distribution; D015032:Zinc / Q000008:administration & dosage / Q000493:pharmacokinetics*; D015037:Zinc Radioisotopes
D015037:Zinc Radioisotopes; D015032:Zinc