[Should antihypertensive pharmacotherapy have occupational limitations?].
Neurophysiologic effects of a course of treatment with reserpin (0.5-0.75 mg/day), dopegyt (750-1500 mg/day), clophelin (0.3-0.6 mg/day), anaprilin (80-160 mg/day), hydrochlorothiazide (25-100 mg/day) were examined in 294 patients with first- and second-stage essential hypertension (EH), using the correction test and the numbers-finding test, determination of the highest data processing rate by the Diagnoz-2 device, and the time of response to sound and light stimulation under monotonous conditions. There were no significant differences in test results between EH patients treated with the above-mentioned drugs and the placebo-treated ones. Neither single doses, nor courses taken in hospital (1 to 3 weeks) or outpatient clinic (6 to 36 months) produced any regular suppressive effect on the neurophysiologic status of EH patients.
Merzon
A K
AK
Logoveeva
T N
TN
Finchenko
V F
VF
D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003864:Depression, Chemical; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D011597:Psychomotor Performance / Q000187:drug effects*; D014938:Work Capacity Evaluation
D000959:Antihypertensive Agents
Nuzhdaetsia antigipertenzivnaia farmakoterapiia v professional'nykh ogranicheniiakh?