Haemocompatibility of segmented polyurethanes investigated in vivo.
Samples of segmented polyurethanes differing in composition and in surface morphology were introduced into the left ventricles of hearts of goats for 72 h. After removal of the samples, their surface and the surface of the heart endothelium were evaluated visually with respect to the formation of thrombi. Differences in the interaction of the individual polyurethanes with blood were examined by XPS photoelectron spectroscopy, SEM, and by infrared (i.r.) reflexion spectroscopy. The results suggest ways for improving the haemocompatibility of the surfaces of polyurethanes used as parts of the total artificial heart.
Fiala
V
V
KUNZ-Research Center, Faculty of Medicine, J.E. Purkynĕ University, Brno, Czechoslovakia.
Sotolová
O
O
Trbusek
V
V
Vrbová
M
M
Vasků
A
A
Urbánek
P
P
Vasků
J
J
Lukás
J
J
Houska
M
M
Tyrácková
V
V
D000818:Animals; D001672:Biocompatible Materials; D001769:Blood; D006041:Goats; D006354:Heart, Artificial; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D011140:Polyurethanes; D013499:Surface Properties
D001672:Biocompatible Materials; D011140:Polyurethanes