Increase of paradoxical sleep (PS) by intraperitoneal injection of brain extract from PS-deprived rats.
Intraperitoneal injection of a brain extract obtained from paradoxical sleep-(PS) deprived donor rats resulted in a small but significant increase of PS in normal recipient rats. Brain extract of non-deprived control rats was without effect. The results provide further evidence for the existence of a PS-inducing factor accumulating in the brain during PS deprivation.
Wetzel
W
W
Institute of Pharmacology and Toxicology, Medical Academy, GDR, Magdeburg.
Stark
H
H
Matthies
H
H
D000818:Animals; D001921:Brain / Q000378:metabolism / Q000502:physiology*; D007274:Injections, Intraperitoneal; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012892:Sleep Deprivation / Q000502:physiology*; D012895:Sleep, REM / Q000187:drug effects / Q000502:physiology*; D013997:Time Factors; D014020:Tissue Extracts / Q000008:administration & dosage / Q000494:pharmacology*
D014020:Tissue Extracts