title: X-ray diffraction study of cholesterol-phosphatidylserine mixtures.
abstract: Phosphatidylserine-cholesterol mixtures at a molar ratio of 2:1 were investigated by X-ray diffraction. Phase separation of cholesterol independent of temperature was detected, indicating limited solubility of cholesterol in phosphatidylserine bilayers. The second phase present, the mixed phospholipid-cholesterol phase, continued to undergo melting as determined by changes with temperature in both the small angle scattering profile and in the acyl chain packing.
authors: Department of Polymer Research, Weizmann Institute of Science, Rehovot, Israel.
authors: E J
authors: EJ
authors: Wachtel
authors: D
authors: D
authors: Bach
mesh_terms: D002784:Cholesterol; D008968:Molecular Conformation; D010718:Phosphatidylserines; D013816:Thermodynamics; D014961:X-Ray Diffraction
chemical_list: D010718:Phosphatidylserines; D002784:Cholesterol