title: The effect of oral contraceptives on the apparent vitamin B6 status in some Sudanese women.
abstract: 1. In vitro activation of erythrocyte aspartate aminotransferase (EC 2.6.1.1) activity by pyridoxal phosphate was used to assess vitamin B6 nutritional status in forty Sudanese women taking combined, low-dose oral contraceptives (oestrogen-progestogen; OC) and in thirty healthy, non-pregnant women not taking OC. 2. Fourteen (35%) out of forty OC users showed apparent vitamin B6 deficiency. 3. Side-effects associated with OC were more common among the apparently vitamin-B6-deficient OC users than among OC users and non-OC users not deficient in vitamin B6.
authors: Faculty of Medicine, University of Khartoum, Sudan.
authors: E Y
authors: EY
authors: Salih
authors: A A
authors: AA
authors: Zein
authors: R A
authors: RA
authors: Bayoumi
mesh_terms: D000293:Adolescent; D000328:Adult; D001219:Aspartate Aminotransferases / Q000378:metabolism; D003276:Contraceptives, Oral / Q000009:adverse effects*; D004789:Enzyme Activation; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009752:Nutritional Status / Q000187:drug effects*; D011732:Pyridoxal Phosphate; D011736:Pyridoxine / Q000378:metabolism*; D012016:Reference Values; D013397:Sudan
chemical_list: D003276:Contraceptives, Oral; D011732:Pyridoxal Phosphate; D001219:Aspartate Aminotransferases; D011736:Pyridoxine