title: [Effect of blastolysin on the ultrastructure and functional activity of mast cells and eosinophils].
abstract: Blastolysin is shown to cause degranulation of mast cells, resulting in a reduction of their histamine content and in their release of mediators that activate eosinophilic leukocytes (EL). These accelerate the deamination of the histamine released by mast cells to the extracellular medium. It is possible that blastolysin acts directly on EL granules which are largely responsible for histamine inactivation.
authors: V A
authors: VA
authors: Teleshev
authors: V G
authors: VG
authors: Zhukov
authors: I A
authors: IA
authors: Gukasian
authors: S M
authors: SM
authors: Spivak
authors: V I
authors: VI
authors: Ogarkov
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D004804:Eosinophils / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D006020:Glycopeptides / Q000494:pharmacology; D008297:Male; D008407:Mast Cells / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D008854:Microscopy, Electron; D051381:Rats
chemical_list: D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D006020:Glycopeptides; C025182:blastolysin
vernacular_title: Vozdeĭstvie blastolizina na ul'trastrukturu i funktsional'nuiu aktivnost' tuchnykh kletok i éozinofilov.