Polytetrafluoroethylene microprosthesis in the arterial system of the rat.
The experimental behavior of a 1-mm internal diameter (i.d.) polytetrafluoroethylene (PTFE) microprosthesis, as a substitute for an abdominal aortic segment in the rat, was reviewed. Fifty Wistar rats were divided into four groups: Group I--12 rats with autotransplant of an abdominal aortic segment (AAS); Group II--12 rats with allotransplant of an AAS obtained from Long-Evans rats; Group III--12 rats with xenotransplant of an AAS taken from rabbit femoral arteries; and Group IV--14 rats with substitution of an AAS by a 1-mm i.d. PTFE microprosthesis. The rats were sacrificed at different time intervals ranging from five to 360 days, with previous aortography. In Group I, there was a 100 percent patency at a mean of 152.41 days; in Group II, a 91.6 percent patency at a mean of 100.08 days; in Group III, an 83.3 percent patency with a 75 percent aneurysmal dilation at a mean of 107.58 days; in Group IV, a 71.42 percent patency with two anastomotic aneurysms at a mean of 105 days (P less than 0.05, chi square) between Groups I and IV, autotransplant vs. PTFE). The 1-mm PTFE microprosthesis placed in the arterial system of the rat proved to be a reliable alternative for microvascular substitution.
Padilla
L
L
Experimental Surgery Service, Universidad Nacional Autónoma de México, Caoyoacán.
Valle
A
A
Carrillo
H
H
Di Silvio
M
M
Contreras
M
M
Viniegra
F
F
Sanchez
R
R
Fajer
J
J
D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery / Q000637:transplantation; D001014:Aortic Aneurysm / Q000473:pathology; D001158:Arteries / Q000473:pathology / Q000601:surgery*; D001705:Bioprosthesis; D001807:Blood Vessel Prosthesis; D008866:Microsurgery / Q000295:instrumentation*; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D014182:Transplantation, Autologous
D011138:Polytetrafluoroethylene