Sex hormone binding globulin in clinical perspective.
The plasma steroid-binding proteins play a fundamental role in the modification and delivery of the steroid "signal" to its target tissue. While their precise function requires further evaluation, the measurement of these proteins, particularly of SHBG, provides clinically useful information. This article reviews the current theories of sex steroid transport and uptake, and documents the changes in SHBG status relevant to health, disease and drug therapy.
Bond
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A
Department of Gynaecology, University of Liverpool.
Davis
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C
D004700:Endocrine System Diseases / Q000378:metabolism; D005260:Female; D005831:Genital Diseases, Female / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D012738:Sex Hormone-Binding Globulin / Q000493:pharmacokinetics* / Q000502:physiology
D012738:Sex Hormone-Binding Globulin; D006854:Hydrocortisone