Use of tartaric acid resistance of beta-glucuronidase for the characterization of cancer cells in pleural effusions.
Tartaric acid was shown to have an inhibiting effect on beta-glucuronidase staining in mesothelial cells and macrophages but not in malignant cells in pleural effusions. Staining for beta-glucuronidase with tartaric acid inhibition is thus suggested for the differentiation of cancer cells from mesothelial cells and macrophages in effusions.
Apibal
S
S
Department of Pathology, Ramathibodi Hospital, Bangkok, Thailand.
Sestapruks
P
P
Bunyaratvej
A
A
Srivannaboon
S
S
Charoenpan
P
P
D001943:Breast Neoplasms / Q000201:enzymology / Q000473:pathology; D002277:Carcinoma / Q000201:enzymology / Q000473:pathology*; D005966:Glucuronidase / Q000037:antagonists & inhibitors*; D006801:Humans; D008175:Lung Neoplasms / Q000201:enzymology / Q000473:pathology*; D008264:Macrophages / Q000201:enzymology; D010996:Pleural Effusion / Q000201:enzymology* / Q000473:pathology; D013644:Tartrates / Q000494:pharmacology*
D013644:Tartrates; D005966:Glucuronidase; C029768:tartaric acid