[Effect of vitamin E and thymalin on the development of experimental allergic encephalomyelitis].
It has been established in the experiments on rats resistant to encephalomyelitis that vitamin E deficiency promoted and thymaline administration prevented the onset of the disease. The experiments on guinea-pigs sensitive to encephalomyelitis have shown that the combined administration of alpha-tocopherol and thymaline prevented the development of the disease. The results obtained make it possible to suggest that the resistance to encephalomyelitis depends on the level of membrane antioxidant defense and the condition of T-cell immunity.
Vilkov
G A
GA
Stepanenko
E M
EM
Kryzhanovskiĭ
G N
GN
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology / Q000517:prevention & control*; D006168:Guinea Pigs; D008297:Male; D051381:Rats; D013951:Thymus Hormones / Q000627:therapeutic use*; D014810:Vitamin E / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D013951:Thymus Hormones; D014810:Vitamin E; C032805:thymalin
Vliianie vitamina E i timalina na razvitie éksperimental'nogo allergicheskogo éntsefalomielita.