[15N-tracer kinetic studies on the utilization of urea in protein metabolism of infants].
The virtual importance of the urea circuit is not clear. After a 3 to 21 day application of 100 mg [15N]-urea/l in 15 infants a [15N]-excess value of 0.06 in serum protein could be proven. Taking as a basis a protein content of 11.4% of the body mass and a regular distribution of the [15N] within the body one can calculate a retention of the urea nitrogen in the protein pool of 40.4% of the intake. Taking in account an amount of 11.4% urea nitrogen from the total nitrogen in mother's milk then the amount of urea nitrogen from the net protein accumulation comes to 6.5 (3.1-11.8)%.
Heine
W
W
Kinderklinik Wilhelm-Pieck-Universität Rostock, DDR.
Stolpe
H J
HJ
Tiess
M
M
Wutzke
W
W
D001798:Blood Proteins / Q000378:metabolism; D004044:Dietary Proteins / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D007553:Isotope Labeling / Q000379:methods; D008895:Milk, Human; D009587:Nitrogen Isotopes; D014508:Urea / Q000378:metabolism*
D001798:Blood Proteins; D004044:Dietary Proteins; D009587:Nitrogen Isotopes; D014508:Urea
15N-tracerkinetische Studien zur Utilisation des Harnstoffs im Eiweissstoffwechsel des Säuglings.