title: Multiple squamous papillomas of the esophagus associated with Goltz syndrome.
abstract: A 30-yr-old white female with a history of focal dermal hypoplasia (Goltz syndrome), chronic gastroesophageal reflux, and dysphagia was found to have, by barium esophagram and esophagogastroduodenoscopy, multiple 2- to 3-mm papillary projections in the distal esophagus and an esophageal stricture. Biopsy of these lesions revealed squamous papillomas and a benign stricture. Although chronic irritation from gastroesophageal reflux has been suggested as a possible etiology of acquired esophageal papillomas, the previous association of congenital papillomas of the oral mucosa in Goltz syndrome suggests that the multiple papillomas in this patient are congenital in origin.
authors: Department of Medicine, Medical College of Georgia, Augusta.
authors: R R
authors: RR
authors: Brinson
authors: B M
authors: BM
authors: Schuman
authors: L R
authors: LR
authors: Mills
authors: S
authors: S
authors: Thigpen
authors: S
authors: S
authors: Freedman
mesh_terms: D000328:Adult; D004476:Ectodermal Dysplasia / Q000151:congenital*; D004938:Esophageal Neoplasms / Q000151:congenital* / Q000628:therapy; D004940:Esophageal Stenosis / Q000628:therapy; D005260:Female; D005489:Focal Dermal Hypoplasia / Q000151:congenital*; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000151:congenital*; D010212:Papilloma / Q000151:congenital* / Q000628:therapy