Magnetic resonance imaging as a screening procedure for methotrexate induced liver damage.
Spin lattice relaxation time (TI) measured with a low field strength magnetic resonance imager in 51 patients with severe psoriasis did not correlate with the histological findings of liver biopsies taken during treatment with oral methotrexate. Liver TI measurement at low magnetic field is of no value as a screening procedure in monitoring methotrexate induced liver damage.
Rademaker
M
M
Department of Dermatology, St Bartholomew's Hospital, West Smithfield, London, U.K.
Webb
J A
JA
Lowe
D G
DG
Meyrick-Thomas
R H
RH
Kirby
J D
JD
Munro
D D
DD
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000139:chemically induced* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008727:Methotrexate / Q000009:adverse effects*; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy
D008727:Methotrexate