title: Childhood problem behavior and neuropsychological functioning in persons at risk for alcoholism.
abstract: The relationship of childhood hyperkinetic and minimal brain dysfunction (Hk-MBD) to neuropsychological functioning was examined in three groups of young adults. Nonalcoholic offspring of an alcoholic parent (N = 21) and of nonalcoholic parents (N = 21) were examined. A comparison group of similar age alcoholic patients (N = 21) was also studied. Each subject completed a battery of neuropsychological test measures and was administered a checklist on the presence of Hk-MBD symptoms in childhood. Offspring of an alcoholic parent and offspring of nonalcoholic parents could not be distinguished on the basis of their cognitive abilities or their frequency of reported Hk-MBD symptoms in childhood. Alcoholic subjects performed more poorly on measures of verbal and performance intelligence and reported a higher frequency of childhood Hk-MBD symptoms. Further, it was found that the frequency of childhood Hk-MBD symptoms was related to poor performance on certain types of cognitive tasks, regardless of group membership. These findings do not support the suggestion that certain cognitive deficits distinguish persons with a family history for alcoholism. However, poor neuropsychological performance in adulthood, at least on certain types of tasks, appears to be associated with the presence of childhood Hk-MBD.
authors: Department of Psychiatry, University of Connecticut Health Center, Farmington 06032.
authors: K L
authors: KL
authors: Workman-Daniels
authors: V M
authors: VM
authors: Hesselbrock
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications / Q000235:genetics* / Q000523:psychology; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000523:psychology*; D003071:Cognition; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D009483:Neuropsychological Tests; D012307:Risk Factors