title: [Characteristics of the morphofunctional status of the tissue in the rat cerebral cortex in experimental renal arterial hypertension].
abstract: Activity of some enzymes in the cerebral cortex of rats with experimentally induced renal arterial hypertension (AH) was studied histochemically. Histologic data provide the evidence for the disturbances in water-salt metabolism in AH. Morphometric study revealed an increase in the specific volume of smaller microvessels and moderate decrease in the specific volume of bigger microvessels. Vascular markers show different time course of activity changes in AH: the activity of alkaline phosphatase increases, while that of alpha-glycerophosphate dehydrogenase remains unchanged. The development of AH is accompanied by the increase in succinic dehydrogenase activity and the decrease in the activity of lactate dehydrogenase in neurons. The changes in the neuron-capillary relationship arising in AH can be one of the possible pathogenetic factors in the pathologic process progression.
authors: E R
authors: ER
authors: Barantsevich
authors: V V
authors: VV
authors: Tomson
authors: V A
authors: VA
authors: Sorokoumov
authors: A A
authors: AA
authors: Skoromets
authors: R I
authors: RI
authors: Valeev
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002540:Cerebral Cortex / Q000201:enzymology / Q000473:pathology*; D005993:Glycerolphosphate Dehydrogenase / Q000378:metabolism; D006978:Hypertension, Renovascular / Q000201:enzymology / Q000473:pathology*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D005993:Glycerolphosphate Dehydrogenase; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D000469:Alkaline Phosphatase
vernacular_title: Osobennosti morfofunktsional'nogo sostoianiia tkani kory golovnogo mozga krys pri éksperimental'noĭ pochechnoĭ arterial'noĭ gipertenzii.