title: Magnetic resonance imaging in temporal lobe epilepsy: pathological correlations.
abstract: A retrospective single-blind study assessing the value of magnetic resonance imaging (MRI) in 48 patients treated surgically for temporal lobe epilepsy was carried out. The imaging findings were correlated with the surgical findings in all cases. Abnormal MRI signals were detected in 34 of 48 (71%) epileptic patients and in 3 of 48 (6.2%) normal or disease control subjects. Twelve patients had structural foreign-tissue lesions, all detected by MRI. Of 14 patients with severe gliosis of the neocortex and/or mesial temporal structures, 11 had abnormal MRI scans. In patients with mild or moderate gliosis of mesial temporal structures, 6 of 12 had abnormal MRI scans. These results indicate that MRI is a sensitive technique for localizing foreign-tissue lesions, mesial temporal sclerosis, and gliosis in patients with intractable temporal lobe seizures.
authors: Department of Neurology and Neurosurgery, McGill University, Montreal Neurological Hospital and Institute, Quebec, Canada.
authors: R
authors: R
authors: Kuzniecky
authors: V
authors: V
authors: de la Sayette
authors: R
authors: R
authors: Ethier
authors: D
authors: D
authors: Melanson
authors: F
authors: F
authors: Andermann
authors: S
authors: S
authors: Berkovic
authors: Y
authors: Y
authors: Robitaille
authors: A
authors: A
authors: Olivier
authors: T
authors: T
authors: Peters
authors: W
authors: W
authors: Feindel
mesh_terms: D000293:Adolescent; D000328:Adult; D001927:Brain Diseases / Q000473:pathology; D002648:Child; D004833:Epilepsy, Temporal Lobe / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D005911:Gliosis / Q000209:etiology / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009474:Neurons / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery