Modelling binary data from a three-period cross-over trial.
A new method of analysing binary data from a three-treatment, three-period cross-over trial is described. This method is based on a log-linear model and mirrors the analysis of continuous data. It is an extension of the method we introduced recently for the analysis of binary data from a two-treatment, two-period cross-over trial. We illustrate our method using data from a trial which compared two analgesics and a placebo for the relief of primary dysmenorrhea.
Jones
B
B
Mathematical Institute, The University, Canterbury, Kent, U.K.
Kenward
M G
MG
D000700:Analgesics / Q000627:therapeutic use; D002986:Clinical Trials as Topic / Q000379:methods*; D003627:Data Interpretation, Statistical; D004412:Dysmenorrhea / Q000188:drug therapy; D005260:Female; D006801:Humans; D008954:Models, Biological; D011336:Probability
D000700:Analgesics