A confidence interval for mutant frequency in assays using microtiter wells.
Previous attempts to derive a confidence interval for the estimated mutant fraction in assays using microtiter wells have not considered the variance introduced by the early growth and dilution steps. We derive a confidence interval that includes these sources of variability.
Javitz
H S
HS
SRI International, Menlo Park, California 94025.
D000704:Analysis of Variance; D006801:Humans; D008214:Lymphocytes / Q000166:cytology; D009154:Mutation; D013223:Statistics as Topic