Swalpamycin, a new macrolide antibiotic. I. Taxonomy of the producing organism, fermentation, isolation and biological activity.
A new macrolide antibiotic, swalpamycin, has been isolated from the culture broth of Streptomyces sp. Y-84,30967. Taxonomically the producing organism most closely resembles Streptomyces anandii and has therefore been named S. anandii subsp. swalpus. Swalpamycin is a neutral 16-membered macrolide active against Gram-positive bacteria including erythromycin-resistant strains.
Franco
C M
CM
Microbiology Department, Research Centre, Hoechst India Limited, Bombay.
Gandhi
J N
JN
Chatterjee
S
S
Ganguli
B N
BN
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005285:Fermentation; D013302:Streptomyces / Q000145:classification* / Q000166:cytology / Q000378:metabolism
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C054350:swalpamycin