title: Potential antitumor agents. I. Synthesis of pyrroloindazole derivatives related to the pyrroloindole moieties of the antitumor antibiotic CC-1065.
abstract: The synthesis of some derivatives of the unknown 1(2),8-dihydropyrrolo[3,2-g]indazole is reported starting from 7-oxo-4,5,6,7-tetrahydroindole. The new pyrroloindazole derivatives resemble the B and C subunit structure of the antitumor antibiotic CC-1065.
authors: Istituto di Chimica Farmaceutica e Tossicologica, Facoltà di Farmacia, Università Degli Studi di Roma, la sapienza, Italy.
authors: S
authors: S
authors: Massa
authors: G
authors: G
authors: Stefancich
authors: M
authors: M
authors: Artico
authors: F
authors: F
authors: Corelli
authors: R
authors: R
authors: Silvestri
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D000080890:Duocarmycins; D007191:Indazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D007211:Indoles; D007933:Leucomycins / Q000138:chemical synthesis* / Q000494:pharmacology; D011720:Pyrazoles / Q000138:chemical synthesis*; D011758:Pyrroles / Q000138:chemical synthesis / Q000494:pharmacology
chemical_list: D000903:Antibiotics, Antineoplastic; D000080890:Duocarmycins; D007191:Indazoles; D007211:Indoles; D007933:Leucomycins; D011720:Pyrazoles; D011758:Pyrroles; C018782:CC 1065