title: Antimicrobial therapy of Broviac catheter infections in pediatric hematology oncology patients.
abstract: Long-term therapy of pediatric oncology patients has been facilitated by permanent indwelling venous catheters. Over a 3-year period, 54 Broviac catheters were placed in 43 oncology patients and two hemophiliacs. There were 20 episodes of sepsis in 14 patients and the most common bacteria were S epidermidis (4), S aureus (4), and K pneumoniae (3). Catheter exit site infections occurred ten times in six patients; S aureus eight of ten. Antibiotic therapy without catheter removal was successful in 18 of 20 children with catheter sepsis and 8 of 10 patients with exit site infections. These data strongly suggest that although catheter-related infections are common, removal of Broviac catheters is not required for successful treatment of the infection.
authors: Walter Reed Army Medical Center, Washington, DC.
authors: T A
authors: TA
authors: Olson
authors: G W
authors: GW
authors: Fischer
authors: M C
authors: MC
authors: Lupo
authors: V F
authors: VF
authors: Garcia
authors: D A
authors: DA
authors: Maybee
authors: J
authors: J
authors: Keiser
authors: K R
authors: KR
authors: Hartman
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006402:Hematologic Diseases / Q000628:therapy*; D006801:Humans; D007223:Infant; D007239:Infections / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D009369:Neoplasms / Q000628:therapy*; D011446:Prospective Studies
chemical_list: D000900:Anti-Bacterial Agents