[Effect of the C35 analog of dolichol on the electrical properties of planar black bilayers].
The effect of C35-dolichol on black planar bilayers from mixture of azolectin and cholesterol has been studied. C35-dolichol in concentration of about 10(-6) g/ml has been found to raise the bilayer conductivity, inducing current jumps with unclearly expressed conductivity level of 0.4-0.5 nSm. According to the data of the first and third harmonic during the several minutes after C35-dolichol addition along one side of the bilayer the capacity of the membranes and transversal module Young increase. It is supposed that dolichols induce the nonbilayer structure in membranes that is the basis for their transfer of oligosaccharides blocks across the membranes of Golgi apparatus.
Korolev
N P
NP
Gus'kova
R A
RA
Mil'gram
V D
VD
Fedorov
G E
GE
Osipov
V I
VI
D004224:Diterpenes / Q000494:pharmacology*; D004286:Dolichols / Q000031:analogs & derivatives / Q000494:pharmacology*; D004553:Electric Conductivity; D008051:Lipid Bilayers; D010539:Permeability
D004224:Diterpenes; D004286:Dolichols; D008051:Lipid Bilayers
Vliianie C35-analoga dolikhola na élektricheskie svoĭstva ploskikh chernykh sloev.