The effects of tick-borne fever on some functions of polymorphonuclear cells of sheep.
Peripheral leucocytes obtained from sheep experimentally infected with tick-borne fever had a significantly reduced capacity to phagocytose and kill Staphylococcus aureus in vitro. Infected neutrophils were also less able to attach to glass surfaces than normal neutrophils. The period of reduced phagocytic activity coincided with the period of parasitaemia and severe neutropenia.
Woldehiwet
Z
Z
University of Liverpool, Department of Veterinary Pathology, Neston, Wirral, U.K.
D000818:Animals; D002448:Cell Adhesion; D005260:Female; D005898:Glass; D008297:Male; D009504:Neutrophils / Q000276:immunology / Q000473:pathology / Q000502:physiology*; D010587:Phagocytosis; D012288:Rickettsiaceae Infections / Q000097:blood / Q000276:immunology / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood* / Q000276:immunology; D013211:Staphylococcus aureus