Maquiroside A, a new cytotoxic cardiac glycoside from Maquira calophylla.
Maquiroside A, a new cardiac glycoside, was isolated from the Peruvian plant Maquira calophylla. The structure was established using spectroscopic methods, and the aglycone was found to be cannogenol. The sugar portion was identified as D-cymarose. Maquiroside A demonstrated activity against the KB cell culture.
Rovinski
J M
JM
Department of Chemistry, Virginia Commonwealth University, Richmond 23284.
Tewalt
G L
GL
Sneden
A T
AT
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification*; D002301:Cardiac Glycosides / Q000302:isolation & purification* / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D008279:Magnetic Resonance Imaging; D010936:Plant Extracts / Q000032:analysis; D010946:Plants, Medicinal / Q000032:analysis*
D000972:Antineoplastic Agents, Phytogenic; D002301:Cardiac Glycosides; D010936:Plant Extracts; C053592:maquiroside A