Effect of some vehicles used in intramammary mastitis preparations on inflammation indicators in milk.
The irritant effect of some vehicles used in intramammary mastitis preparations was assessed by indirect mastitis indicators in milk. Mineral oil, soybean oil, peanut oil, a combination of aluminium monostearate, stearic acid and mineral oil as well as isotonic saline were infused intracisternally in cows during mid-lactation. These vehicles induced a selective increase in the number of somatic cells without any notable effects on the permeability marker antitrypsin or the lysosomal enzyme N-acetyl-beta-D-glucosaminidase (NAGase).
Pyörälä
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Ambulatory Clinic, College of Veterinary Medicine, Hautjärvi, Finland.
D000118:Acetylglucosaminidase / Q000032:analysis*; D000818:Animals; D002417:Cattle; D005260:Female; D006596:Hexosaminidases / Q000032:analysis*; D007774:Lactation / Q000187:drug effects; D008321:Mammary Glands, Animal / Q000187:drug effects*; D008414:Mastitis, Bovine / Q000188:drug therapy* / Q000473:pathology; D008892:Milk / Q000166:cytology* / Q000187:drug effects / Q000201:enzymology; D014677:Pharmaceutical Vehicles / Q000494:pharmacology*; D011247:Pregnancy; D014361:Trypsin Inhibitors / Q000032:analysis*
D014677:Pharmaceutical Vehicles; D014361:Trypsin Inhibitors; D006596:Hexosaminidases; D000118:Acetylglucosaminidase