Haemodynamic changes during silent myocardial ischaemia.
The haemodynamic significance of asymptomatic ST segment depression has been assessed in patients with coronary artery disease by direct measurement of left ventricular end-diastolic pressure (LVEDP) or pulmonary artery end-diastolic pressure (PADP). Both techniques have demonstrated a rise in pressure during such episodes of ST segment depression recorded in the Coronary Care Unit, cardiac catheter and exercise laboratories or during ambulant activity. Thus silent or asymptomatic ST segment depression is associated with similar haemodynamic changes to that seen during angina pectoris and has considerable therapeutic implications.
Levy
R D
RD
St Bartholomew's Hospital, London.
Fox
K M
KM
D000787:Angina Pectoris / Q000503:physiopathology*; D000789:Angina, Unstable / Q000503:physiopathology*; D003327:Coronary Disease / Q000503:physiopathology*; D004562:Electrocardiography; D005080:Exercise Test; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D009200:Myocardial Contraction; D011669:Pulmonary Wedge Pressure