[Thermochemotherapy of unresectable pancreatic carcinoma (hot water and intra-arterial chemotherapy using noradrenaline)].
A 86-year-old man with unresectable pancreatic carcinoma was treated with thermochemotherapy. In most of the body and tail affected by the tumor, which did not show any cytotoxic damage after intraarterial chemotherapy, an enhanced antitumor effect was achieved by hyperthermia, which heated the tumor using hot water in a balloon placed on the pancreas, and which was delivered through a vinyl tube leading out of the body for 40 minutes while administration of antitumor agents mixed with noradrenaline was simultaneously given into the celiac artery. In this case, we observed that using noradrenaline with contrast material injected into the celiac artery it was possible to delineate the tumor area by computed tomography of the pancreas.
Sato
T
T
Dept. of Surgery, Koriyama Natl. Hospital.
Sekine
S
S
Katsumi
S
S
Yokogi
K
K
Watanabe
S
S
Murai
T
T
Rikimaru
Y
Y
Kawaguchi
T
T
Abe
R
R
D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007261:Infusions, Intra-Arterial; D008297:Male; D009638:Norepinephrine / Q000008:administration & dosage*; D010190:Pancreatic Neoplasms / Q000628:therapy*
D005472:Fluorouracil; D009638:Norepinephrine