A statistical test for synergism of two cell growth inhibitors.
Interaction of 2 inhibitors of cell growth can be detected by measuring the inhibiting effect of the 2 drugs separately and in combination. A control group is used as the basis for each comparison. We discuss a method for the statistical analysis of such measurements, when the basic observation is the number of cells harvested from a treated culture.
Bloomfield
P
P
Department of Statistics, North Carolina State University, Raleigh 27695-8203.
Eastwood
B
B
D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004357:Drug Synergism; D009025:Morpholines / Q000494:pharmacology; D013223:Statistics as Topic; D013806:Theophylline / Q000494:pharmacology
D009025:Morpholines; C037574:morpholine; D013806:Theophylline