Specificity of pulmonary vascular lesions in primary pulmonary hypertension. A reappraisal.
The type and distribution of pulmonary vascular lesions in 23 cases of primary pulmonary hypertension were reviewed. 15 cases were classified as plexogenic arteriopathy. The remaining cases displayed thromboembolic lesions. All cases showed a predominance of eccentric intimal lesions. In the plexogenic group, mixed concentric and eccentric intimal fibrosis coexisted. Therefore, in the present study, we propose an objective descriptive approach to the diagnosis of hypertensive pulmonary vascular disease, to correlate morphology and function.
Pietra
G G
GG
Department of Pathology, University of Pennsylvania Medical School, Philadelphia.
Rüttner
J R
JR
D000328:Adult; D000368:Aged; D000635:Aminorex / Q000009:adverse effects; D001067:Appetite Depressants / Q000009:adverse effects; D005260:Female; D005352:Fibromuscular Dysplasia / Q000473:pathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000139:chemically induced / Q000473:pathology*; D008875:Middle Aged; D011651:Pulmonary Artery / Q000473:pathology*; D011655:Pulmonary Embolism / Q000473:pathology*; D011668:Pulmonary Veno-Occlusive Disease / Q000473:pathology
D001067:Appetite Depressants; D000635:Aminorex