title: Terbutaline treatment inhibits the hCG-induced increase in venular permeability in the rat testis.
abstract: Treatment with hCG results in an increase in venular permeability in the rat testis. This change in vascular permeability can be detected by the carbon-labelling technique, by measurement of the volume of interstitial fluid and by quantification of the leucocyte migration into the interstitial space. Carbon-labelling, interstitial fluid volume and leucocyte migration were all reduced in rats treated with hCG+ terbutaline compared to the values in animals given hCG only. However, terbutaline treatment did not influence the hCG-induced increase in testosterone secretion. These observations suggest that the hCG-induced increase in vascular permeability in the testis can be reduced by a beta-adrenergic agonist.
authors: Department of Anatomy and Pathology, University of Umeå, Sweden.
authors: A
authors: A
authors: Bergh
authors: J E
authors: JE
authors: Damber
mesh_terms: D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects*; D002244:Carbon; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D005110:Extracellular Space / Q000187:drug effects; D007962:Leukocytes / Q000166:cytology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013726:Terbutaline / Q000494:pharmacology*; D013737:Testis / Q000098:blood supply* / Q000166:cytology / Q000187:drug effects; D013739:Testosterone / Q000378:metabolism; D014699:Venules / Q000187:drug effects
chemical_list: D006063:Chorionic Gonadotropin; D013739:Testosterone; D002244:Carbon; D013726:Terbutaline