title: [Clinical experience with atracurium--a continuous infusion technic].
abstract: A continuous infusion technique for atracurium was investigated. It provided a stable neuromuscular block, with a mean infusion rate of 0.008 mg/kg/min after an initial bolus of 0.5 mg/kg. A wide individual response was found and an arbitrary infusion rate based on mass alone is therefore not possible. The above rate is thus a starting point and should be adjusted according to individual requirements, preferably by using a peripheral nerve stimulator. The technique obviates the need for repeated increments of atracurium during lengthy surgical procedures.
authors: Departement Anestesiologie, Universiteit van Pretoria.
authors: P J
authors: PJ
authors: Fourie
authors: M
authors: M
authors: Versace
authors: P A
authors: PA
authors: Lambert
authors: A J
authors: AJ
authors: Lessing
mesh_terms: D000328:Adult; D001279:Atracurium / Q000008:administration & dosage* / Q000494:pharmacology; D006801:Humans; D007262:Infusions, Intravenous; D009407:Nerve Block / Q000379:methods*; D013997:Time Factors
chemical_list: D001279:Atracurium
vernacular_title: Kliniese ondervinding met atrakurium--'n aanhoudende infusie-tegniek.