[Prognostic value of the level of steroid hormone receptors in cancer of the large intestine].
Clinical course of 77 surgical cases of cancer of the large bowel was evaluated versus levels of estrogen, androgen, progesterone and glucocorticoid hormone receptors. Within the follow-up period (range 6-41 months), 7 (9%) patients died of tumor progression, 16 (21%) developed recurrence or metastases, while the rest 54 (70%) cases continued in remission. Patients with steroid hormone receptor-positive tumors revealed more favorable clinical course as well as longer disease-free and overall survival than cases of receptor-negative cancer. Estrogen receptor status was found to be of the highest prognostic value in terms of clinical course and survival, as compared to all other hormone receptors studied.
Bassalyk
L S
LS
Korotkova
T V
TV
Prorokov
V V
VV
Murav'eva
N I
NI
Smirnova
K D
KD
D000230:Adenocarcinoma / Q000032:analysis* / Q000401:mortality / Q000473:pathology; D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000032:analysis* / Q000401:mortality / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011379:Prognosis; D011944:Receptors, Androgen / Q000032:analysis; D011960:Receptors, Estrogen / Q000032:analysis; D011965:Receptors, Glucocorticoid / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D011987:Receptors, Steroid / Q000032:analysis*; D013997:Time Factors
D011944:Receptors, Androgen; D011960:Receptors, Estrogen; D011965:Receptors, Glucocorticoid; D011980:Receptors, Progesterone; D011987:Receptors, Steroid
Prognosticheskoe znachenie urovnia retseptorov steroidnykh gormonov pri rake tolstoĭ kishki.