Trabecular bone density and menstrual function in women runners.
Osteoporosis results in decreased bone mineral mass and reduced trabecular bone density. Although its etiology remains unknown, studies have revealed differential changes in the bone mineral densities of postmenopausal women, anorexic women, and amenorrheic female athletes. Correlations have also been made between estrogen deficiency and osteoporosis in both premenopausal and postmenopausal women. In order to examine the possibility of osteopenia, a group of 36 female runners between the ages of 15 and 44 years were evaluated for bone mineral density, menstrual function, and dietary habits. Serum calcium, phosphorus, and parathyroid hormone (PTH) levels were also determined for each participant, as were complete blood counts. Using dual photon absorptiometry, all participants underwent a 20 minute scan of the lumbar spine with specificity to the L1-14 vertebrae. The 36 subjects included 19 oligomenorrheic and 17 eumenorrheic women. Results of bone density analyses revealed that the oligomenorrheic runners had significantly lower calibrated bone mineral density (CBMD) than their eumenorrheic counterparts (P less than or equal to 0.01). Likewise, the PTH levels of the oligomenorrheic runners were also significantly lower (P less than or equal to 0.01). Analysis of dietary logs revealed no significant differences between the dietary habits, the calcium intake, or the caloric intake of the two groups. The data from this study indicate that there is a relationship between reduced serum PTH levels and the oligomenorrheic state. The loss of the protective effect of estrogen in the oligomenorrheic runners possibly contributed to their reduced bone mineral densities and could be a contributing factor in osteopenia.
Cook
S D
SD
Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, LA 70112.
Harding
A F
AF
Thomas
K A
KA
Morgan
E L
EL
Schnurpfeil
K M
KM
Haddad
R J
RJ
D000293:Adolescent; D000328:Adult; D001842:Bone and Bones / Q000032:analysis; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000378:metabolism*; D008903:Minerals / Q000032:analysis; D009839:Oligomenorrhea / Q000097:blood / Q000209:etiology / Q000378:metabolism*; D010024:Osteoporosis / Q000097:blood / Q000209:etiology / Q000378:metabolism*; D010758:Phosphorus / Q000097:blood; D012420:Running
D008903:Minerals; D010758:Phosphorus; D002118:Calcium