5'-Hydroxyisoavrainvilleol, a new diphenylmethane derivative from the tropical green alga Avrainvillea nigricans.
A new brominated diphenylmethane, 5'-hydroxyisoavrainvilleol, was isolated from the tropical green macrophyte, Avrainvillea nigricans, using conventional chromatographic techniques. The structure is based on a combination of spectrochemical arguments, including a detailed analysis of the long range 1H-13C coupling constants. The natural product shows gram-positive antimicrobial activity.
Colon
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Department of Chemistry, University of Puerto Rico, Rio Piedras.
Guevara
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Gerwick
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Ballantine
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D000107:Acetylation; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects; D001559:Benzhydryl Compounds / Q000302:isolation & purification / Q000494:pharmacology / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D000460:Chlorophyta / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D001559:Benzhydryl Compounds; C053756:5-hydroxyisoavrainvilleol