The effect of twice daily nadolol on intraocular pressure.
The 12-hour control of intraocular pressure obtained with 10 and 20 mg of nadolol twice daily was studied in a placebo-controlled trial. In this ten-week study involving 17 patients a significant reduction in intraocular pressure was obtained with both doses. The effect of 20 mg of nadolol twice daily on intraocular pressure, resting pulse rate, and blood pressure was consistently slightly greater than 10 mg twice daily, but the difference was not significant.
Duff
G R
GR
Department of Ophthalmology, University Hospital of Wales, Cardiff, U.K.
D004311:Double-Blind Method; D004334:Drug Administration Schedule; D004417:Dyspnea / Q000139:chemically induced; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D009248:Nadolol / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D010349:Patient Compliance; D012894:Sleep Stages
D009248:Nadolol