title: Resting energy expenditure of host and tumor is similar in rats with methylcholanthrene-induced sarcoma.
abstract: In the present study we assessed the resting energy expenditure of 30 free-feeding control and methylcholanthrene-induced sarcoma-bearing rats prior to and following surgical removal of the tumor. Tumor-bearing rats demonstrated carcass wasting and massive tumor growth. The resting energy expenditure data in our model suggest that neither the presence and growth of a tumor nor its removal significantly change resting energy expenditure beyond the normal range for non-tumor-bearing rats. We suggest that in the partition of energy costs between host and tumor, both carry a similar input, proportional to their relative weight, into the total combined resting energy expenditure of host and tumor.
authors: Department of Surgery, University of Cincinnati Medical Center, OH 45267.
authors: H R
authors: HR
authors: Freund
authors: M W
authors: MW
authors: Kim
authors: M
authors: M
authors: Muggia-Sullam
authors: W T
authors: WT
authors: Chance
authors: J E
authors: JE
authors: Fischer
mesh_terms: D000818:Animals; D004734:Energy Metabolism; D008748:Methylcholanthrene; D009929:Organ Size; D051381:Rats; D011916:Rats, Inbred F344; D012513:Sarcoma, Experimental / Q000139:chemically induced / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D013997:Time Factors
chemical_list: D008748:Methylcholanthrene