Iron status in Ecuadorian pregnant women living at 2,800 m altitude: relationship with infant iron status.
An evaluation of iron status was performed in 84 pregnant women at delivery (and in cord blood from their newborn) and in a control group of 32 menstruating women living in Quito (2800 m altitude). Anemia as defined according to the WHO references adjusted to altitude was observed in 46% of pregnant women. Iron deficiency was defined as the combination of a low serum ferritin level (12 micrograms/l or less) and a low transferrin saturation percentage (less than 16%). A moderate elevation in the serum ferritin concentration (between 13 and 50 micrograms/l) associated with low transferrin saturation indicated iron deficiency in an inflammatory context. Iron deficiency was present in 46% of pregnant women. Anemia was associated with iron deficiency in 59% of cases. A correlation between maternal and cord blood hemoglobin was found and some iron parameters in cord blood were related to maternal iron status, and especially to maternal iron stores assessed by serum ferritin concentration.
Yepez
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Laboratorio de Investigaciones de Bioquimica, Facultad de Ciencias Medicas de Quito (Ecuador), Paris, France.
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Galan
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Estevez
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Davila
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Estrella
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Masse-Raimbault
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Hercberg
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D000531:Altitude; D000747:Anemia, Hypochromic / Q000453:epidemiology; D004484:Ecuador; D005260:Female; D005312:Fetal Blood / Q000032:analysis; D006801:Humans; D007231:Infant, Newborn; D007249:Inflammation / Q000453:epidemiology; D000090463:Iron Deficiencies; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011250:Pregnancy Complications, Hematologic / Q000453:epidemiology