title: [Comparison of the sensitivity of Rhodococcus rubropertinctus R, S and M variants to antibiotic action].
abstract: Comparison of sensitivity of 63 clones of R, S and M variants of Rhodococcus rubropertinctus 104 to 6 antibiotics showed that sensitivity of the variants was similar only to erythromycin. Their sensitivity to penicillin, streptomycin, chlortetracycline, rifampicin and actinomycin C was different. Still, they preserved similar regularity: M cells were the most sensitive and R cells were the most resistant. There was a 1.5-3 fold difference in sensitivity of R and M variants to the antibiotics. The number and rate of chlortetracycline absorption by R cells were lower than those of S and especially M cells which must condition their higher resistance to the antibiotic.
authors: E S
authors: ES
authors: Mil'ko
authors: N S
authors: NS
authors: Egorov
authors: E
authors: E
authors: Vuĭtsik
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D014644:Genetic Variation / Q000187:drug effects*; D006020:Glycopeptides / Q000032:analysis / Q000494:pharmacology / Q000633:toxicity; D008826:Microbial Sensitivity Tests; D012240:Rhodococcus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents; D006020:Glycopeptides; C053759:eremomycin
vernacular_title: Sravnenie chuvstvitel'nosti R-, S- i M-variantov Rhodococcus rubropertinctus k deĭstviiu antibiotikov.