title: A rapid and simplified extraction of haloperidol from plasma or serum with bond elut C18 cartridge for analysis by high performance liquid chromatography.
abstract: This method for the determination of haloperidol (HAL) in plasma is based on high-performance liquid chromatography (HPLC) with a reversed-phase column, ODS-C18. HAL is rapidly extracted from human plasma by using Bond Elut C18 cartridge and its recovery is over 90%. The mobile phase is a mixture of 1% acetate/acetonitrile/tetrahydrofuran/triethylamine (69.5: 28.2:1.9:0.4, by vol.). The method is rapid, simple and free from intereferences and gives good precision.
authors: Department of Legal Medicine, School of Medicine, Hirosaki University, Japan.
authors: M
authors: M
authors: Hayakari
authors: Y
authors: Y
authors: Hashimoto
authors: T
authors: T
authors: Kita
authors: S
authors: S
authors: Murakami
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004305:Dose-Response Relationship, Drug; D006220:Haloperidol / Q000097:blood*; D006801:Humans; D014229:Triazolam / Q000097:blood
chemical_list: D014229:Triazolam; D006220:Haloperidol