title: [Immunoglobulin A and its significance for mucosa immunity--a contribution to the understanding of microbial interactions].
abstract: The secretory immunoglobulin A is still dominating with regard to knowledges and further investigations of the causes of mucosal immunity. Origin, formation, structure and mode of action of s-IgA are extensively explored. In the clinical range results of researches on symptoms and consequences of selective IgA deficiency are gaining importance, increasingly. Patients with IgA defect suffer up to 40 times more frequently from allergies and autoimmunopathies. In the induction of the immune response cellular components of mucosa immunity attaining the Lamina propria and the epithelium with the effector cells of Peyer's patches play a particular role.
authors: Zentralinstitut für Mikrobiologie und experimentelle Therapie, Akademie der Wissenschaften der DDR.
authors: A
authors: A
authors: Stelzner
authors: A
authors: A
authors: Groh
authors: K H
authors: KH
authors: Vogt
authors: M
authors: M
authors: Kittlick
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity; D007070:Immunoglobulin A / Q000276:immunology*; D007413:Intestinal Mucosa / Q000276:immunology*; D009092:Mucous Membrane / Q000276:immunology
chemical_list: D007070:Immunoglobulin A
vernacular_title: Immunglobulin A und seine Bedeutung für die Schleimhautimmunität--ein Beitrag zum Verständnis mikrobieller Interaktionen.