Minimal-change nephrotic syndrome in adults treated with alternate-day steroids.
Fifty-eight previously untreated adults with minimal-change nephrotic syndrome (MCNS), who had a mean follow-up period of 35.8 months, were studied with regard to their response to alternate-day steroid therapy. The nephrotic syndrome in 54 patients (93%) remitted by 12 weeks and patients continued to be in remission at 16 weeks. Of the 54 patients, 8 (14.8%) had frequent relapses and 9 (16.6%) had infrequent relapses. No serious complications as a result of steroid therapy were encountered.
Nair
R B
RB
Department of Nephrology, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
Date
A
A
Kirubakaran
M G
MG
Shastry
J C
JC
D000293:Adolescent; D000328:Adult; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009402:Nephrosis, Lipoid / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage*; D012189:Retrospective Studies
D011239:Prednisolone