title: Circadian profiles and circaseptan periodicity in the frequency of administration of analgetic drugs after oral surgery.
abstract: The frequencies of 5706 demands for analgetic drugs after dental operations have been recorded. The highest consumption of analgetics is observed around postoperative day 7. On days 2 and 3, the circadian course of the frequencies peaks in the early morning (around 06.00). On days 6 and 7 the frequencies of analgetic administrations increase during the evening (around 18.00-20.00). The circadian profiles of frequencies therefore exhibit a phase jump of about 180 degrees during the postoperative period, indicating a change of dominance from a more protopathic type of pain to an epicritic one.
authors: Institut für Arbeitsphysiologie und Rehabilitationsforschung Philipps-Universität Marburg, Federal Republic of Germany.
authors: L
authors: L
authors: Pöllmann
authors: G
authors: G
authors: Hildebrandt
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage*; D000328:Adult; D002940:Circadian Rhythm; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D010149:Postoperative Pain / Q000188:drug therapy*
chemical_list: D000082:Acetaminophen