Muscle relaxants in multiple sclerosis.
Spasticity is an important cause of physical impediment in multiple sclerosis. Only drug therapy offers useful (but not universal) relief. Dantrolene sodium and/or baclofen are the drugs of choice, being both effective and clinically suitable in over half of cases when carefully titrated and monitored.
Basmajian
J V
JV
Department of Medicine, McMaster University and Rehabilitation Centre, Hamilton, Ontario, Canada.
D001418:Baclofen / Q000627:therapeutic use*; D003620:Dantrolene / Q000627:therapeutic use*; D006801:Humans; D009103:Multiple Sclerosis / Q000150:complications*; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology
D003620:Dantrolene; D001418:Baclofen