[Study of complex lipids. Synthesis of diphosphatidylglycerol (cardiolipin) with unsaturated fatty acid residues].
Diphosphatidylglycerol (cardiolipin) with different fatty acid residues has been synthesised by condensation of 1,2-diacyl-sn-glycero-3-phosphoric acid (obtained, e.g., by the cabbage phospholipase D cleavage of 1,2-dioleyl-sn-glycero-3-phosphocholine or egg phosphatidylcholine) with 2-O-tert-butyldimethylsilylglycerol in the presence of 2,4,6-triisopropylbenzenesulphonylchloride. The synthetic cardiolipins as unsonicated aqueous calcium-free dispersions were shown, by means of 31P NMR spectroscopy, to form aggregates of the bilayer structure.
Mishina
I M
IM
Vasilenko
I A
IA
Stepanov
A E
AE
Shvets
V I
VI
D002308:Cardiolipins / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D002855:Chromatography, Thin Layer; D005231:Fatty Acids, Unsaturated; D009682:Magnetic Resonance Spectroscopy; D013010:Sonication; D013055:Spectrophotometry, Infrared
D002308:Cardiolipins; D005231:Fatty Acids, Unsaturated
Issledovaniia v oblasti slozhnykh lipidov. Sintez difosfatidilglitserina (kardiolipina) s nenasyshchennymi zhirnokislotnymi ostatkami.