Antigenic variation of Newcastle disease viruses isolated from wild ducks in Japan.
Nineteen strains of Newcastle disease virus (NDV) isolated from wild ducks in Japan were placed into 4 distinct antigenic groups on the basis of their reactivities to 8 monoclonal antibodies against the HN molecule of NDV in hemagglutination inhibition tests. The NDV strains of duck origin were antigenically distinct from NDV-B1 and NDV-Miyadera originated from chickens, and varied in their virulence to chicken embryos. No apparent correlation was found between the antigenicity of the HN molecule and virulence.
Kawamura
M
M
Department of Epizootiology, Faculty of Veterinary Medicine, Hokkaido University.
Nagata-Matsubara
K
K
Nerome
K
K
Yamane
N
N
Kida
H
H
Kodama
H
H
Izawa
H
H
Mikami
T
T
D000818:Animals; D000835:Animals, Wild; D000911:Antibodies, Monoclonal / Q000276:immunology; D000940:Antigenic Variation; D000956:Antigens, Viral / Q000276:immunology*; D004372:Ducks / Q000382:microbiology*; D006385:Hemagglutination Inhibition Tests; D007564:Japan; D009521:Newcastle Disease / Q000382:microbiology*; D009522:Newcastle disease virus / Q000145:classification / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral