[Treatment of severe uveitis with cyclosporin A].
The results of a treatment with ciclosporin A in 4 patients with severe uveitis (2 cases with Behçet's disease, 2 cases Vogt-Koyanagi-Harada disease) are presented. Ciclosporin A produced a rapid regression of exudates in the ocular fundus and of the inflammatory signs at the anterior segment in the 4 cases. However, at the same time, side effects including the deterioration of the hepatorenal function developed. Interruption of the treatment with ciclosporin A led to the development of inflammation at the anterior and posterior segments in cases 2 and 4.
Harada
T
T
Clinique ophtalmologique universitaire, Nagoya, Japan.
Sugita
K
K
Saito
A
A
Awaya
S
S
D000328:Adult; D001528:Behcet Syndrome / Q000150:complications; D003524:Cyclosporins / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014605:Uveitis / Q000188:drug therapy* / Q000209:etiology; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications
D003524:Cyclosporins
Traitement des uvéites sévères par la ciclosporine A.