Binding of (125I) triiodothyronine to human peripheral leukocytes and its internalization.
Ultrastructural autoradiography showed high specific binding of (125I) triiodothyronine, as confirmed by a competition test, to plasma membranes, nuclei and mitochondria of human peripheral leukocytes. A high level of binding was also noted on the granulocytes' granules, especially in eosinophils.
Kostrouch
Z
Z
1st Department of Pathology, Charles University, Prague, Czechoslovakia.
Felt
V
V
Raska
I
I
Nedvídková
J
J
Holecková
E
E
D001667:Binding, Competitive; D002462:Cell Membrane / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D003594:Cytoplasmic Granules / Q000378:metabolism; D006098:Granulocytes / Q000378:metabolism; D006801:Humans; D007457:Iodine Radioisotopes; D007962:Leukocytes / Q000378:metabolism*; D008214:Lymphocytes / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D014284:Triiodothyronine / Q000097:blood*
D007457:Iodine Radioisotopes; D014284:Triiodothyronine