Neoplastic angioendotheliosis.
Neoplastic angioendotheliosis is a rare disease in which malignant cells are found within numerous blood vessels throughout the body in the absence of any detectable extravascular primary malignancy. The disorder has a propensity for clinical neurological involvement despite pathological evidence of systemic spread. To date 23 patients with neurological involvement have been described. This report adds a further 3 cases. There was no definite evidence to support the theory that the malignancy arises in endothelial cells; no primary extravascular tumour was found. At present a definite conclusion about the cause of the disease cannot be made.
Brew
B J
BJ
Department of Neurology, St Vincent's Hospital, Sydney, New South Wales.
O'Sullivan
D J
DJ
Darveniza
P
P
Selby
G
G
Fryer
J
J
Evans
W
W
D000368:Aged; D001158:Arteries / Q000473:pathology; D001921:Brain / Q000098:blood supply / Q000473:pathology; D002544:Cerebral Infarction / Q000473:pathology; D004730:Endothelium, Vascular / Q000473:pathology; D006390:Hemangioendothelioma / Q000473:pathology*; D006801:Humans; D007238:Infarction / Q000473:pathology; D008297:Male; D009360:Neoplastic Cells, Circulating; D013116:Spinal Cord / Q000098:blood supply / Q000473:pathology; D014680:Veins / Q000473:pathology