[A new experimental design for the in vitro evaluation of drug absorption in topical forms. 1. Design and model calculation].
An in-vitro model is presented which consists on several membrane Layers. The penetration of drugs from the ointment bases into these membrane Layers is observed. By combination of different membranes this system can be varied. In model calculations the resulting conditions are demonstrated.
Fürst
W
W
Martin-Luther-Universität, Halle-Wittenberg, Sektion Pharmazie.
Neubert
R
R
Wildner
R
R
Beyrich
G
G
Bendas
C
C
D000287:Administration, Topical; D008567:Membranes, Artificial; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000008:administration & dosage; D010599:Pharmacokinetics
D008567:Membranes, Artificial; D004364:Pharmaceutical Preparations
Eine neue Versuchsanordnung zur in-vitro-Beurteilung der Wirkstoffresorption aus topischen Arzneiformen. 1. Mitteilung: Versuchsanordnung und Modellrechnungen.