[Clinical experience with atracurium--a continuous infusion technic].
A continuous infusion technique for atracurium was investigated. It provided a stable neuromuscular block, with a mean infusion rate of 0.008 mg/kg/min after an initial bolus of 0.5 mg/kg. A wide individual response was found and an arbitrary infusion rate based on mass alone is therefore not possible. The above rate is thus a starting point and should be adjusted according to individual requirements, preferably by using a peripheral nerve stimulator. The technique obviates the need for repeated increments of atracurium during lengthy surgical procedures.
Fourie
P J
PJ
Departement Anestesiologie, Universiteit van Pretoria.
Versace
M
M
Lambert
P A
PA
Lessing
A J
AJ
D000328:Adult; D001279:Atracurium / Q000008:administration & dosage* / Q000494:pharmacology; D006801:Humans; D007262:Infusions, Intravenous; D009407:Nerve Block / Q000379:methods*; D013997:Time Factors
D001279:Atracurium
Kliniese ondervinding met atrakurium--'n aanhoudende infusie-tegniek.