Hypothermia enhances acetylcholine-induced contraction of isolated rat ileum.
The amplitude of acetylcholine (ACh)-induced contraction of isolated rat ileum was enhanced at medium temperatures lower than normal body temperature. Maximum enhancement was achieved between 30 and 25 degrees C. Changes in medium pH and activities of the enteric nervous system due to temperature changes were not essential for this enhancement.
Nagai
M
M
Department of Physiology, Medical University of Yamanashi, Japan.
Toda
H
H
Iriki
M
M
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D003080:Cold Temperature; D007082:Ileum / Q000187:drug effects*; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D051381:Rats
D000109:Acetylcholine