Thiamine deficiency encephalopathy with concurrent myocardial degeneration and polyradiculoneuropathy in a cat.
Hyaline degeneration, myofiber fragmentation, and mineralization were present in the left ventricle of an aged, female Siamese cat with both clinical and histopathological evidence suggestive of a thiamine deficiency encephalopathy. Both a thiamine related biochemical lesion and neurogenic myocardial degeneration ("Brain-Heart" Syndrome) may have contributed to the development of the heart lesions. A concurrent lumbar polyradiculoneuropathy, characterized by ballooning myelin sheaths with axonal degeneration, was considered an incidental, age-related finding.
Anderson
W I
WI
Department of Veterinary Pathology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
Morrow
L A
LA
D000818:Animals; D001927:Brain Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D009202:Cardiomyopathies / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D005260:Female; D011129:Polyradiculoneuropathy / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D013832:Thiamine Deficiency / Q000150:complications / Q000473:pathology / Q000662:veterinary*