Hereditary angioedema and aortitis.
A 28-year-old male with hereditary angioedema died of an extensive stroke. Autopsy revealed cicatricial aortitis with narrowing of the coronary ostia, myocardial infarctions, and a left ventricular mural thrombus. There was neither acute inflammation of the aorta nor systemic vasculitis. A possible association of the aortitis with the hereditary angioedema is discussed.
Hoffmann
U
U
Innere Medizin, Universität Heidelberg, Klinikum Mannheim.
Buss
J
J
Voigtlaender
V
V
Berlit
P
P
Bernbeck
U
U
Heene
D
D
D000328:Adult; D000799:Angioedema / Q000235:genetics* / Q000473:pathology; D001011:Aorta / Q000473:pathology; D001025:Aortitis / Q000235:genetics* / Q000473:pathology; D002536:Cerebral Arteries / Q000473:pathology; D002544:Cerebral Infarction / Q000235:genetics / Q000473:pathology; D003174:Complement C1 Inactivator Proteins / Q000172:deficiency; D006801:Humans; D008297:Male; D010375:Pedigree
D003174:Complement C1 Inactivator Proteins