Swalpamycin, a new macrolide antibiotic. II. Structure elucidation.
A new antibiotic swalpamycin (1) has been isolated from the culture broth of Streptomyces sp. Y-84,30967. The antibiotic has the molecular formula of C37H56O14 and belongs to the class of 16-membered neutral macrolide antibiotics. Its structure has been elucidated by an analysis of its spectral properties. It contains a novel aglycone herein called swalpanolide.
Chatterjee
S
S
Research Centre, Hoechst India Limited, Bombay.
Reddy
G C
GC
Franco
C M
CM
Rupp
R H
RH
Ganguli
B N
BN
Fehlhaber
H W
HW
Kogler
H
H
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D055598:Chemical Phenomena; D002621:Chemistry; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; C054350:swalpamycin