Insect antifeedant activity and hot taste for humans of selected natural and synthetic 1,4-dialdehydes.
The antifeedant activity towards larvae of Leptinotarsa decemlineata and Spodoptera littoralis and the hot taste for the human tongue have been determined for natural and synthetic 1,4-dialdehydes. Among the bicyclic dialdehydes the biological activity has been found to be dependent on the distance between the two aldehyde groups; tricyclic and pentacyclic dialdehydes are inactive in both tests. A short synthetic route to (-)- and (+)-polygodial is reported.
Caprioli
V
V
Istituto per la Chimica di Molecole di Interesse Biologico, CNR, Napoli, Italy.
Cimino
G
G
Colle
R
R
Gavagnin
M
M
Sodano
G
G
Spinella
A
A
D000447:Aldehydes / Q000138:chemical synthesis / Q000494:pharmacology*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005247:Feeding Behavior / Q000187:drug effects*; D006801:Humans; D007313:Insecta / Q000502:physiology*; D013329:Structure-Activity Relationship; D013649:Taste / Q000187:drug effects*
D000447:Aldehydes