Plasma histamine levels in normal and atopic children.
Plasma histamine was measured in 258 children by using a sensitive high performance liquid chromatographic method. A normal level of histamine, which was high at a lower age and low at a higher age, was determined. Atopic children had higher levels than normal children. The extent of atopic disease had a relationship with higher levels. The correlations between plasma histamine and basophil count and between plasma histamine and IgE were significant in atopic children but not in normal children.
Fujisawa
T
T
Department of Pediatrics, Mie National Hospital, Mie Prefecture, Japan.
Komada
M
M
Iguchi
K
K
Uchida
Y
Y
D000293:Adolescent; D000328:Adult; D001491:Basophils; D002648:Child; D004804:Eosinophils; D005260:Female; D006632:Histamine / Q000097:blood*; D006801:Humans; D006967:Hypersensitivity / Q000097:blood* / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis; D007958:Leukocyte Count; D008297:Male
D007073:Immunoglobulin E; D006632:Histamine