Tracing of afferent pathways from the femoral-saphenous vein to the dorsal root ganglia using transport of horseradish peroxidase.
The retrograde transport of horseradish peroxidase (HRP) was used to trace afferents from the femoral-saphenous vein to the dorsal root ganglia in the cat. Afferents arising along the entire length of the vein projected to very localized spinal levels; 63% of the labeled cells counted were located in the L6 dorsal root ganglion, 37% were located in the L5 ganglion and less than 1% were located at other levels. Most of the cell bodies labeled by the application of HRP to the femoral-saphenous vein were small in size (diameter less than 35 microns). However, some large cell bodies (diameter greater than 50 microns) were also noted. It was estimated that over two-thirds of the femoral-saphenous venous afferents were C fibers; at least 15% were estimated to be A fibers. The largest venous afferents were predicted to conduct action potentials at approximately 60 m/s.
Yates
B J
BJ
Department of Neuroscience, College of Veterinary Medicine, University of Florida, Gainesville 32610.
Mickle
J P
JP
Hedden
W J
WJ
Thompson
F J
FJ
D000344:Afferent Pathways / Q000033:anatomy & histology / Q000201:enzymology; D000818:Animals; D001693:Biological Transport, Active; D002415:Cats; D005268:Femoral Vein / Q000294:innervation*; D005727:Ganglia, Spinal / Q000033:anatomy & histology* / Q000201:enzymology; D006735:Horseradish Peroxidase / Q000493:pharmacokinetics; D012501:Saphenous Vein / Q000294:innervation*
D006735:Horseradish Peroxidase