Production of bacteriocin-like agents of Budvicia aquatica and "Pragia fontium".
In cultures of 9 budvicia aquatica and 5 "Pragia fontium" strains production of distinct bacteriocin-like agents was proved. It is suggested to call them aquaticins and fonticins. They display strain specific antibacterial activities towards both genera; however, they are not active towards Escherichia coli or Shigella sonnei indicators. Their inhibition zones are conspicuously narrow (turbid or clear). Their spontaneous production may be enhanced by UV-induction of producing bacteria. They are readily set free into the medium; no intracellular accumulation occurs. With only one exception, they are trypsin-resistant and remarkably heat-sensitive, being damaged at 45 degrees C to 55 degrees C. All these results suggest that aquaticins and fonticins are of corpuscular character. This assumption was proved true by electron microscopic observation of one of the fonticins: this resembles contracted tails of bacteriophage T4.
Smarda
J
J
Department of Biology, Medical Faculty, J.E. Purkynĕ University, Brno, Czechoslovakia.
D001430:Bacteriocins / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D003470:Culture Media; D004755:Enterobacteriaceae / Q000378:metabolism* / Q000528:radiation effects / Q000648:ultrastructure; D006358:Hot Temperature; D008854:Microscopy, Electron; D014357:Trypsin / Q000494:pharmacology; D014466:Ultraviolet Rays
D001430:Bacteriocins; D003470:Culture Media; D014357:Trypsin