title: Choanal atresia and associated anomalies.
abstract: The authors have studied 130 cases of choanal malformation. They found 53 bilateral atresias, 51 unilateral atresias and 26 cases of choanal stenosis. Fifty-seven of these cases were associated with other anomalies and 38 had at least two features of the CHARGE association (C, colobomas; H, heart defects; A, atresia choanae; R, retarded growth; G, genito-urinary defects; E, ear defects). The pathogenesis of choanal atresia in regard to the abnormal migration of neuroectodermal cells is discussed.
authors: Department of Otolaryngology, Centre Hospitalier de l'Université Laval, Quebec City, Canada.
authors: J E
authors: JE
authors: Leclerc
authors: B
authors: B
authors: Fearon
mesh_terms: D000015:Abnormalities, Multiple / Q000150:complications*; D002648:Child; D002754:Choanal Atresia / Q000150:complications* / Q000453:epidemiology; D003103:Coloboma / Q000150:complications; D004423:Ear / Q000002:abnormalities; D005260:Female; D005317:Fetal Growth Retardation / Q000150:complications; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D008297:Male; D011247:Pregnancy; D014564:Urogenital Abnormalities