title: Malignant hyperpyrexia and isoflurane. A case report.
abstract: Malignant hyperpyrexia developed, and was successfully treated, in a 50-year old man undergoing pyelolithotomy. Early diagnosis with the assistance of end-tidal carbon dioxide monitoring facilitated prompt treatment with i.v. dantrolene. A positive muscle biopsy subsequently confirmed the diagnosis. The only likely triggering agent used was isoflurane.
authors: Department of Anaesthetics, Morriston Hospital, Cwmrhydyceirw, Swansea.
authors: D W
authors: DW
authors: Thomas
authors: V J
authors: VJ
authors: Dev
authors: M J
authors: MJ
authors: Whitehead
mesh_terms: D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D003620:Dantrolene / Q000627:therapeutic use; D006801:Humans; D007431:Intraoperative Complications / Q000209:etiology; D007530:Isoflurane / Q000009:adverse effects*; D008297:Male; D008305:Malignant Hyperthermia / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged
chemical_list: D007530:Isoflurane; D003620:Dantrolene