DNA and cell cycle analysis of retinoblastoma.
We retrospectively analyzed archival retinoblastomas from 44 eyes. The percentage of cycling cells were increased in younger patients, those with advanced disease, and cases with poor prognosis. These data suggest that all cell cycle studies may yield important insights in retinoblastoma.
Char
D H
DH
Department of Ophthalmology, University of California, San Francisco 94143.
Huhta
K
K
Meecham
W J
WJ
D000375:Aging / Q000502:physiology; D000782:Aneuploidy; D002453:Cell Cycle; D004247:DNA / Q000378:metabolism*; D005134:Eye Neoplasms / Q000235:genetics* / Q000473:pathology; D006801:Humans; D012175:Retinoblastoma / Q000235:genetics* / Q000473:pathology; D012189:Retrospective Studies
D004247:DNA