Detergent induced lysis of erythrocytes in kwashiorkor.
The effect of the non-ionic detergent Nonidet P40 on lysis of erythrocytes in children suffering from kwashiorkor was studied. The concentration of the detergent causing 50% haemolysis was significantly reduced in these patients. Detergent haemolysis was more sensitive than osmotic fragility (which was reduced). The abnormality was only slight in marasmic children.
Rao
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A
Department of Chemical Pathology, A.B.U. Hospital, Zaria, Nigeria.
Onuora
C U
CU
Cherian
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A
D000740:Anemia / Q000097:blood; D002648:Child; D003902:Detergents / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D007038:Hypotonic Solutions; D007732:Kwashiorkor / Q000097:blood* / Q000175:diagnosis; D017830:Octoxynol; D011092:Polyethylene Glycols / Q000494:pharmacology; D013501:Surface-Active Agents / Q000494:pharmacology*
D003902:Detergents; D007038:Hypotonic Solutions; D013501:Surface-Active Agents; D011092:Polyethylene Glycols; D017830:Octoxynol; C010615:Nonidet P-40