Class I major histocompatibility complex antigens and C4 concentrations in sheep plasma.
Data are presented demonstrating that high concentrations of complement protein C4 in sheep plasma are associated with a particular class I OLA specificity. By way of contrast, a similar association could not be demonstrated between C3 plasma concentrations and OLA specificities. These data support the hypothesis that gene(s) determining C4 plasma concentrations are linked to the ovine MHC.
Groth
D M
DM
School of Medical Technology, Western Australia Institute of Technology.
Wetherall
J D
JD
Outerridge
P
P
Stear
M J
MJ
D000818:Animals; D003176:Complement C3 / Q000032:analysis / Q000235:genetics; D003181:Complement C4 / Q000032:analysis / Q000235:genetics*; D006649:Histocompatibility Antigens / Q000032:analysis*; D008285:Major Histocompatibility Complex; D010641:Phenotype; D012756:Sheep
D003176:Complement C3; D003181:Complement C4; D006649:Histocompatibility Antigens