Retroequatorial red retinal lesions in sickle cell anemia.
We report 2 patients with sickle cell anemia who showed retroequatorial localized red retinal lesions. In 1 patient these lesions were associated with closure of the retinal precapillary arteriole and capillary bed. In both patients these lesions receded during the course of therapy with a selective arteriolar vasodilator, nifedipine. These observations are discussed in relation to the possible pathogenesis of the retinopathy seen in patients with sickle cell anemia.
Roy
M S
MS
National Eye Institute, Clinical Branch, Bethesda, Md.
Rodgers
G P
GP
Noguchi
C T
CT
Schechter
A N
AN
D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D009543:Nifedipine / Q000627:therapeutic use; D012164:Retinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*
D009543:Nifedipine