Synergism between a phosphodiesterase inhibitor and modulators of thromboxane formation on thrombin-induced sudden death in rabbits.
Smith
E F
EF
Research Department, Ciba-Geigy Corp., Summit, NJ.
Olson
R W
RW
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D019086:Bridged Bicyclo Compounds, Heterocyclic; D003645:Death, Sudden; D004357:Drug Synergism; D005231:Fatty Acids, Unsaturated; D006834:Hydrazines / Q000494:pharmacology*; D007093:Imidazoles / Q000494:pharmacology*; D007213:Indomethacin / Q000494:pharmacology*; D007546:Isoquinolines / Q000494:pharmacology*; D008297:Male; D011725:Pyridines / Q000494:pharmacology*; D011817:Rabbits; D044005:Tetrahydroisoquinolines; D013917:Thrombin / Q000633:toxicity*; D013927:Thrombosis / Q000503:physiopathology; D013928:Thromboxane A2 / Q000037:antagonists & inhibitors*; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors*
D019086:Bridged Bicyclo Compounds, Heterocyclic; D005231:Fatty Acids, Unsaturated; D006834:Hydrazines; D007093:Imidazoles; D007546:Isoquinolines; D011725:Pyridines; D044005:Tetrahydroisoquinolines; D013928:Thromboxane A2; C035964:trequinsin; C045749:SQ 29548; C037787:pirmagrel; D013917:Thrombin; D013930:Thromboxane-A Synthase; D007213:Indomethacin