Anaphylaxis to intravenous furosemide.
A patient with long-standing hypertension developed urticaria, angioedema, and hypotension within 5 minutes after the intravenous administration of furosemide. Immediate hypersensitivity was documented by positive skin tests to furosemide as well as to related sulfonamide-based drugs. This is the first finding of an anaphylactic reaction to furosemide and underscores the need to consider such adverse reactions when patients who are sensitive to other sulfonamide-containing drugs are being treated.
Hansbrough
J R
JR
Howard Hughes Medical Institute Laboratories, Washington University School of Medicine, St. Louis, Mo 63110.
Wedner
H J
HJ
Chaplin
D D
DD
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D055598:Chemical Phenomena; D002621:Chemistry; D005665:Furosemide / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D012882:Skin Tests
D005665:Furosemide