Constituents of Tritonia crocosmaeflora, I. Tricrozarin A, a novel antimicrobial naphthazarin derivative.
A novel naphthazarin derivative, tricrozarin A, has been isolated from the fresh bulbs of Tritonia crocosmaeflora and was characterized as 5,8-dihydroxy-2,3-dimethoxy-6,7-methylenedioxy-1,4-naphthoquinone (2,3-dimethoxy-6,7-methylenedioxynaphthazarin). Tricrozarin A exhibits antimicrobial activity against gram-positive bacteria, fungi, and yeast in vitro and is the first tetra-oxygenated naphthazarin derivative isolated from higher plants.
Masuda
K
K
Kitasato Institute, Tokyo, Japan.
Funayama
S
S
Komiyama
K
K
Umezawa
I
I
Ito
K
K
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D008826:Microbial Sensitivity Tests; D009285:Naphthoquinones / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000032:analysis*
D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; C053757:tricrozarin A