Metabolic and hormonal status of crewmembers in short-term spaceflights.
In order to clarify biochemical adaptation of the human body to short-term microgravity, metabolic and hormonal parameters were investigated in 20 cosmonauts who performed orbital flights of 4 to 14 d in duration. The specific feature of adaptation to this exposure is the transition to a new level of hormonal regulation with a significant increase of the content (production) of glucocorticoids, catecholamines, components of the renin-angiotensin-aldosterone system, which determines a modified activity of tissue hormones, and fluid-electrolyte homeostasis, as well as simultaneous increase of insulin secretion that diminishes the metabolic effects of glucocorticoids and catecholamines.
Grigoriev
A I
AI
Institute of Biomedical Problems, Moscow, U.S.S.R.
Popova
I A
IA
Ushakov
A S
AS
D000222:Adaptation, Physiological; D002395:Catecholamines / Q000378:metabolism; D005938:Glucocorticoids / Q000378:metabolism; D006706:Homeostasis; D006728:Hormones / Q000378:metabolism; D006801:Humans; D012084:Renin-Angiotensin System; D013026:Space Flight; D014882:Water-Electrolyte Balance; D014893:Weightlessness
D002395:Catecholamines; D005938:Glucocorticoids; D006728:Hormones