Fatality resulting from metoprolol overdose.
A death due to an intentional overdose of metoprolol is described. The drug was quantified by gas chromatography, and identification was confirmed by gas chromatography/mass spectrometry. Metoprolol concentrations in blood, bile, urine, and vitreous humor were 19.8 mg/L, 83.1 mg/L, 1.6 mg/L, and 15.1 mg/L, respectively. A blood ethanol concentration of 0.25 g/100 mL was the only other significant toxicologic finding.
Rohrig
T P
TP
Kansas Bureau of Investigation, Toxicology Laboratory, Topeka 66612.
Rundle
D A
DA
Leifer
W N
WN
D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*; D008875:Middle Aged; D013405:Suicide
D008790:Metoprolol