Gnotobiological research of the host-microflora interaction.
The last two decades indicate that one of the main features of modern gnotobiology are comparative experiments on germfree and conventional counterparts to study the significance of normal (or dysbiotic) microflora (or individual species) in various physiological and pathological processes of the host organism. There are some immunological consequences of absence of normal microflora. Interactions between some indigenous and pathogenic bacteria in the intestine of gnotobiotic and conventional rats are discussed.
Chakhava
O V
OV
Laboratory of Gnotobiology, N. F. Gamaleya Institute for Epidemiology and Microbiology, USSR Academy of Medical Sciences, Moscow.
Gorskaya
E M
EM
D000818:Animals; D005856:Germ-Free Life; D007422:Intestines / Q000382:microbiology* / Q000502:physiology; D012107:Research Design