title: Laboratory transmission of lymphatic filariasis by vector mosquitoes.
abstract: Aedes togoi and Ae. aegypti were used to examine the transmission potential of Brugia pahangi to one of its natural hosts, the domestic cat. Although a larger proportion of microfilariae taken in by Ae. togoi developed into infective larvae, the total number of B. pahangi larvae recovered from a cat exposed to Ae. aegypti was larger than from a cat exposed to Ae. togoi. Factors influencing the transmission dynamics included: development of microfilariae to infective larvae; survival of mosquitoes; willingness to take repeated blood meals; and proportion of infective larvae that egress from mosquitoes during the feeding process. From 19 to 25% of infective larvae were transferred to a susceptible host. The feasibility of using a Brugia-cat model to do comparative vector efficiency studies was demonstrated.
authors: Department of Parasitology, National Yang-Ming Medical College, Taipei, Taiwan, R.O.C.
authors: A
authors: A
authors: Ewert
authors: C C
authors: CC
authors: Wu
authors: P C
authors: PC
authors: Fan
mesh_terms: D000330:Aedes / Q000469:parasitology*; D000818:Animals; D002009:Brugia / Q000472:pathogenicity*; D002415:Cats; D005368:Filariasis / Q000469:parasitology / Q000635:transmission*; D007303:Insect Vectors / Q000469:parasitology*