[Antioxidant capacity of the blood serum of schizophrenic patients in relation to brain tissue as an index of its neurotropic activity].
The authors have proposed a method of determining the neurotropic activity of the blood serum, which is based on the ability of cytotoxic anticerebral antibodies to intensify the processes of lipid peroxidation in the homogenate of the rat brain. Sera of the overwhelming majority of the 175 schizophrenics studied showed neurotropic activity. At the stage of exacerbation patients with different forms of schizophrenia showed identical neurotropic activity while at the stage of remission this activity was significantly different as compared with both the value characteristic of the exacerbation stage and the control one.
Vilkov
G A
GA
Siletskiĭ
O Ia
OIa
Stepanenko
E M
EM
D000818:Animals; D001790:Blood Physiological Phenomena; D001921:Brain / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D010084:Oxidation-Reduction; D051381:Rats; D012559:Schizophrenia / Q000097:blood*
Antiokislitel'naia sposobnost' syvorotki krovi bol'nykh shizofrenieĭ po otnosheniiu k tkani mozga kak pokazatel' ee neĭrotropnosti.