title: Effects of glucose transport on the incorporation of 32P-inorganic phosphate into phospholipids in Hymenolepis diminuta (Cestoda).
abstract: 1. The absorption of glucose and alpha-methyl-D-glucoside by Hymenolepis diminuta was concentration dependent. 2. alpha-Methyl-D-glucoside competitively inhibited glucose absorption and was not metabolised by the parasite. 3. alpha-Methyl-D-glucoside significantly lowered (P less than 0.05) the incorporation of 32Pi into all phospholipid classes. 4. Glucose inhibited (P less than 0.01) 32Pi incorporation into phosphatidylcholine only. 5. Phlorizin did not affect 32Pi labelling of phospholipids. 6. Serotonin and histamine stimulated (P less than 0.01) 32Pi labelling of all phospholipid classes. 7. Radioactivities in water soluble fractions were increased (P less than 0.01) in the presence of glucose, serotonin and histamine.
authors: Department of Zoology, National University of Singapore, Kent Ridge.
authors: M M
authors: MM
authors: Khan
authors: Y Y
authors: YY
authors: Chua
authors: Y K
authors: YK
authors: Ip
mesh_terms: D000818:Animals; D001693:Biological Transport, Active; D005947:Glucose / Q000378:metabolism*; D006926:Hymenolepis / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008757:Methylglucosides / Q000378:metabolism / Q000494:pharmacology; D010695:Phlorhizin / Q000494:pharmacology; D010710:Phosphates / Q000378:metabolism*; D010743:Phospholipids / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D008757:Methylglucosides; D010710:Phosphates; D010743:Phospholipids; C027020:methylglucoside; D010695:Phlorhizin; D005947:Glucose