Effect of animal and vegetable fats and proteins on distribution of cholesterol in plasma and organs of young growing pigs.
Young, growing pigs were fed for 8 wk diets containing either soy protein isolate or ground beef as the main protein source and soybean oil or beef tallow as the main fat source to examine effects of types of dietary protein and fat on cholesterol distribution between blood plasma, plasma lipoproteins and body organs. Type of dietary protein did not influence concentrations of a) cholesterol in plasma, b) low-density-lipoprotein (LDL) cholesterol, c) high-density-lipoprotein (HDL) cholesterol or d) cholesterol in several organs of pigs. Pigs fed tallow had greater concentrations of plasma cholesterol and LDL and HDL cholesterol than did pigs fed soybean oil. Ratios of HDL to LDL were not altered by dietary fat. Cholesterol concentrations were greater in heart, skeletal muscle and viscera of pigs fed soybean oil than in those fed tallow. Plasma cholesterol varied reciprocally with cholesterol in several tissues. Thus, dietary beef and soy protein isolate had similar effects on cholesterol concentrations in plasma, LDL, HDL and organs, whether pigs consumed soybean oil or beef tallow as a major fat source. Soybean oil, however, exerted a hypocholesterolemic effect, irrespective of major source of dietary protein.
Baldner-Shank
G L
GL
Department of Animal Science, Iowa State University, Ames 50011.
Richard
M J
MJ
Beitz
D C
DC
Jacobson
N L
NL
D000818:Animals; D002417:Cattle; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000378:metabolism*; D004041:Dietary Fats / Q000494:pharmacology*; D004044:Dietary Proteins / Q000494:pharmacology*; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008460:Meat; D014674:Plant Proteins, Dietary / Q000494:pharmacology; D011897:Random Allocation; D013024:Soybean Oil / Q000494:pharmacology; D030262:Soybean Proteins; D013552:Swine / Q000254:growth & development / Q000378:metabolism*; D014018:Tissue Distribution
D002791:Cholesterol, Dietary; D004041:Dietary Fats; D004044:Dietary Proteins; D008074:Lipoproteins; D014674:Plant Proteins, Dietary; D030262:Soybean Proteins; D013024:Soybean Oil; D002784:Cholesterol