Primary hyperparathyroidism in dogs: 21 cases (1976-1986).
Case records from 21 dogs with hypercalcemia and hyperparathyroidism were evaluated. The dogs were greater than or equal to 7 years old, and 6 were Keeshonds. The most common clinical signs were polydipsia/polyuria, listlessness, and muscle weakness. The serum calcium concentrations were 12.1 to 19.6 mg/dl. Serum phosphorus concentrations were low in 5 dogs, within the reference range in 13 dogs, and high in 3 dogs that also had high concentrations of BUN. Twenty dogs had a parathyroid adenoma, and 1 had a parathyroid carcinoma. Nineteen dogs had their parathyroid tumor surgically removed. Within 5 days of tumor removal, 11 of the 19 dogs became hypocalcemic and the remaining 8, normocalcemic. Nine of the 11 hypocalcemic dogs developed clinical signs. Iatrogenic hypercalcemia was induced in 7 of 16 dogs treated orally with calcium carbonate plus vitamin D. Only 1 of 19 dogs that had their parathyroid tumor excised died in hypocalcemic tetany. Two additional dogs died within 2 weeks of surgery, one because of pancreatitis, the other due to renal failure. Eight dogs died 9 to 37 months after surgery of unrelated problems. Eight dogs were alive for at least 7 to 28 months after surgery.
Berger
B
B
Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616.
Feldman
E C
EC
D000236:Adenoma / Q000662:veterinary; D000818:Animals; D001806:Blood Urea Nitrogen / Q000662:veterinary; D002118:Calcium / Q000097:blood / Q000627:therapeutic use; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D005260:Female; D006934:Hypercalcemia / Q000662:veterinary; D006961:Hyperparathyroidism / Q000662:veterinary*; D006996:Hypocalcemia / Q000662:veterinary; D008297:Male; D010280:Parathyroid Glands / Q000601:surgery; D010282:Parathyroid Neoplasms / Q000662:veterinary; D010758:Phosphorus / Q000097:blood; D012189:Retrospective Studies; D014807:Vitamin D / Q000627:therapeutic use
D014807:Vitamin D; D010758:Phosphorus; D002118:Calcium