[Facilitation of memory trace retrieval by the action of amfonelic acid].
Amfonelic acid exerting the central dopaminergic effect was studied on mice by the passive avoidance conditioned response method under amnesia induced by leaving the animals in a dark chamber following electrocutaneous stimulation and different terms of natural forgetting. Amfonelic acid was shown to prevent the amnesic effect, to improve retrieval of the conditioned response decreased as a result of amnesia or prolonged forgetting.
Il'iuchenok
R Iu
RIu
Dubrovina
N I
NI
Vinnitskiĭ
I M
IM
D000647:Amnesia / Q000209:etiology / Q000503:physiopathology; D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects; D004924:Escape Reaction / Q000187:drug effects; D008297:Male; D008568:Memory / Q000187:drug effects*; D008570:Memory, Short-Term / Q000187:drug effects; D011939:Mental Recall / Q000187:drug effects*; D051379:Mice; D008807:Mice, Inbred BALB C; D009268:Nalidixic Acid / Q000031:analogs & derivatives; D009287:Naphthyridines / Q000494:pharmacology*; D013997:Time Factors
D009287:Naphthyridines; D009268:Nalidixic Acid; C006486:amfonelic acid
Oblegchenie vosproizvedeniia sleda pamiati pri deĭstvii amfonelevoĭ kisloty.