N-mononitrosopiperazine in urine after occupational exposure to piperazine.
We have shown previously that intake of the drug piperazine can result in the endogenous formation of N-mononitrosopiperazine (NPZ; Bellander et al., 1985). The present investigation deals with the possibility of endogenous formation of NPZ due to occupational exposure to piperazine in a chemical plant.
Bellander
T
T
Department of Occupational Medicine, Lund University Hospital, Sweden.
Osterdahl
B G
BG
Hagmar
L
L
D002617:Chemical Industry; D004781:Environmental Exposure; D006801:Humans; D009566:Nitrates / Q000032:analysis; D009573:Nitrites / Q000032:analysis; D009602:Nitrosamines / Q000652:urine*; D000077489:Piperazine; D010879:Piperazines / Q000009:adverse effects*; D012463:Saliva / Q000032:analysis
D009566:Nitrates; D009573:Nitrites; D009602:Nitrosamines; D010879:Piperazines; D000077489:Piperazine; C014711:1-nitrosopiperazine