title: Dynamics of equi-factor antibodies in sera of foals kept on farms with differing histories of Rhodococcus equi pneumonia.
abstract: The occurrence of equi-factor antibodies in sera of mares and their foals was studied on two horse breeding farms, one of which (Farm A) had a positive and the other (farm B) a negative history of R. equi infection of foals. The equi-factor neutralization (EFN) and the reverse Elek-Ouchterlony (REO) precipitation were used as assays. On Farm A, 25 mares positive in both tests (EFN+ REO+) and 25 mares negative in both tests (EFN- REO-) was chosen. On Farm B, a group of 25 EFN- REO+ mares and a group of 25 EFN- REO- mares were studied. The first serum samplings in mares were 1 week ante partum and the subsequent samplings in both mares and foals were in the first week after birth and at the end of every month of the foals' age up to 6 months, with further samplings at 8 and 12 months. A higher number of seropositive foals was found on Farm A, but the difference between Farms A and B was not significant. The smallest number, with the lowest titres, was among the foals of EFN- REO+ dams. The number of foals positive in the REO test was higher than in the EFN test. The onset of EFN positivity was found in foals on both farms in the first month of their age, always culminating in the third and fourth months in titres varying between 1:64 and 1:2048, after which time it fell until it disappeared altogether or reached values of 1:4. The results showed the widespread nature of subclinical infection with R. equi on horse farms.(ABSTRACT TRUNCATED AT 250 WORDS)
authors: School of Veterinary Medicine, Brno, Czechoslovakia.
authors: B
authors: B
authors: Skalka
mesh_terms: D000193:Actinomycetales Infections / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D000907:Antibodies, Bacterial / Q000032:analysis*; D005260:Female; D006734:Horse Diseases / Q000276:immunology / Q000382:microbiology*; D006736:Horses / Q000276:immunology*; D009500:Neutralization Tests; D011014:Pneumonia / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D049590:Postpartum Period / Q000276:immunology; D011247:Pregnancy; D012240:Rhodococcus / Q000276:immunology*
chemical_list: D000907:Antibodies, Bacterial