Peptide nitrosation in dilute acid.
Rates and products are reported for the nitrosation of simple dipeptides (glycylglycine, its ethyl ester and N-acetylglycylglycine) in dilute acid at 37 degrees C. The results suggest that conversion to a diazo derivative (which rapidly decomposes) is the most likely outcome of the gastric nitrosation of small proteins and peptides.
Challis
B C
BC
Chemistry Department, Imperial College, London, UK.
Glover
B R
BR
Pollock
J R
JR
D004151:Dipeptides / Q000378:metabolism; D006033:Glycylglycine / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008433:Mathematics; D009603:Nitroso Compounds / Q000378:metabolism*; D010455:Peptides / Q000378:metabolism*
D004151:Dipeptides; D009603:Nitroso Compounds; D010455:Peptides; C037929:N-acetylglycylglycine; D006033:Glycylglycine