Abnormal prolactin response to haloperidol challenge in men with schizophrenia.
Fourteen drug-free male patients with schizophrenia had a smaller and slower prolactin response to 0.5 mg of intravenous haloperidol than 14 normal age- and sex-matched control subjects. This finding supports the presence of dopaminergic dysfunction in schizophrenia.
Keks
N A
NA
Mental Health Research Institute of Victoria, Parkville, Australia.
Copolov
D L
DL
Singh
B S
BS
D000328:Adult; D004298:Dopamine / Q000502:physiology; D006220:Haloperidol / Q000494:pharmacology*; D006801:Humans; D008297:Male; D011388:Prolactin / Q000097:blood*; D012559:Schizophrenia / Q000097:blood* / Q000175:diagnosis / Q000503:physiopathology
D011388:Prolactin; D006220:Haloperidol; D004298:Dopamine