title: [Morphofunctional characteristics of the thyroid gland in intact and partially sympathectomized rats of different age groups].
abstract: The morphological and functional age-dependent changes have been studied in the thyroid gland of infantile (1-month-old), immature (2- and 3-month-old) and sexually mature (6-month-old) male rats. The decrease in thyroid functional activity with ageing was proved. Chemical sympathectomy (guanethidine at a dose of 15 mg/kg intramuscularly for 14 days after birth) was accompanied not only by morphological reconstruction of the thyroid tissue, but also (especially in 1-month-old rats) by a delay in transport-organic phase of iodine metabolism and a decline in thyroid hormone serum level. Later on, the compensatory hormonogenesis reinforcement occurs as a result of partial adrenergic innervation recovery.
authors: S N
authors: SN
authors: Riashchikov
authors: V A
authors: VA
authors: Glumova
authors: V N
authors: VN
authors: Markov
authors: A A
authors: AA
authors: Zelenin
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D008297:Male; D051381:Rats; D013563:Sympathectomy, Chemical; D013564:Sympathetic Nervous System / Q000502:physiology*; D013961:Thyroid Gland / Q000166:cytology / Q000502:physiology*; D013963:Thyroid Hormones / Q000097:blood
chemical_list: D013963:Thyroid Hormones
vernacular_title: Morfofunktsional'naia kharakteristika shchitovidnoĭ zhelezy intaktnykh i chastichno desimpatizirovannykh krys raznykh vozrastnykh grupp.