Dietary calcium intake and bone loss from the spine in healthy postmenopausal women.
Controversy exists over the relationship between calcium intake and axial bone loss. We measured bone density of the spine (L2-4) by dual photon absorptiometry (DPA) two times, 7 mo apart, in 76 healthy postmenopausal women aged 40-70 y. Ca intake was assessed by food-frequency questionnaire. Women with a Ca intake less than 405 mg/d lost spine density at a rate that was significantly greater than that of women with an intake greater than 777 mg/d, p = 0.026. There appears to be a threshold of Ca intake below which increased Ca in the diet is likely to be beneficial in reducing spine mineral loss.
Dawson-Hughes
B
B
USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111.
Jacques
P
P
Shipp
C
C
D000368:Aged; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000494:pharmacology*; D004032:Diet; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D008903:Minerals / Q000378:metabolism; D009751:Nutritional Requirements; D013131:Spine / Q000378:metabolism*
D008903:Minerals; D002118:Calcium