Vascular responsiveness of isolated and perfused simian metacarpal veins to several vasoconstrictor substances.
Using the cannula inserting method, vascular responses to 7 vasoconstrictor substances were investigated on isolated, perfused simian metacarpal veins. The vein was markedly constricted by an intraluminal administration of norepinephrine, phenylephrine and 5-hydroxytryptamine with a maximal increase in perfusion pressure of over 100 mmHg. Clonidine and xylazine induced only a slight vasoconstriction, but tyramine produced no significant constriction. A large dose of KCl induced a strong vasoconstriction. In this study, it was demonstrated that the simian metacarpal vein has a specific characteristic of vascular reactivity.
Ito
T
T
Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.
Chiba
S
S
D000818:Animals; D005260:Female; D006225:Hand / Q000098:blood supply; D066298:In Vitro Techniques; D008251:Macaca; D008297:Male; D012867:Skin / Q000098:blood supply*; D014662:Vasoconstrictor Agents / Q000494:pharmacology*; D014680:Veins / Q000187:drug effects
D014662:Vasoconstrictor Agents