Female to male mortality ratios for alcohol-related disorders: possible indicator of susceptibility in different sexes.
We investigated the possibility that organs other than liver in women were more susceptible to alcohol than in men. Female:male cirrhosis mortality ratio in different countries was used as an index of female susceptibility to alcohol. The F:M cirrhosis ratio correlated significantly with F:M ratios for cerebrovascular disease and cancers of the esophagus, liver and lung. This preliminary evidence suggests that other organs and/or disease processes in women may be affected more by alcohol than in men.
Nanji
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Department of Pathology, University of Ottawa, Canada.
French
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SW
D000437:Alcoholism / Q000150:complications*; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000401:mortality; D004938:Esophageal Neoplasms / Q000209:etiology / Q000401:mortality; D005260:Female; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000401:mortality*; D008297:Male; D012744:Sex Ratio