title: [Pedunculated polypoid gangliocytic paraganglioma of the afferent jejunal loop of a Billroth II stomach].
abstract: A mobile pedunculated polypoid tumor was endoscopically removed from the afferent jejunal loop after gastrojejunostomy of a 54-year-old patient with anamnestic evidence of intestinal bleeding. Histologically epithelial carcinoid-like as well as mesenchymal paraganglioma- and ganglioneuroma-like patterns are mixed in varying portions, characteristic for gangliocytic paraganglioma. Immunohistochemically, serotonin, neuron-specific enolase, cytokeratin, vimentin S-100 protein and neurofilament were demonstrable. Gangliocytic paragangliomas are almost exclusively observed in the second portion of the duodenum, especially around the papilla Vateri and only two have previously been reported in the jejunum. The histogenesis of the tumors is unclear, but they may probably be either hamartomas, hyperplastic or neoplastic proliferations of so called endodermal-neuroectodermal complexes. Although gangliocytic paragangliomas contain a carcinoid-like component, they behave in a benign fashion, and metastases or recidives have not been noticed. Tumors with a pedicle may be endoscopically removed without complications.
authors: Institut für Pathologie Mönchengladbach, Freien Universität Berlin.
authors: V
authors: V
authors: Grouls
authors: H
authors: H
authors: Pickartz
authors: H E
authors: HE
authors: Reis
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005743:Gastrectomy; D006801:Humans; D007417:Intestinal Polyps / Q000473:pathology* / Q000601:surgery; D007580:Jejunal Neoplasms / Q000473:pathology* / Q000601:surgery; D007583:Jejunum / Q000473:pathology; D008875:Middle Aged; D010235:Paraganglioma / Q000473:pathology* / Q000601:surgery; D010437:Peptic Ulcer / Q000601:surgery*; D011183:Postoperative Complications / Q000473:pathology*
vernacular_title: Gestieltes polypöses gangliozytisches Paragangliom der zuführenden Jejunumschlinge eines Billroth-II-Magens.