title: In vitro autoradiography of [3H]acetylcholine binding in rat hind limb muscles.
abstract: The morphological distribution of acetylcholine receptors in normal and denervated rat tibialis anterior and soleus muscles was studied by in vitro quantitative autoradiography with [3H]acetylcholine (ACh). In normal muscles [3H]ACh binding was restricted to the neuromuscular junction, while denervated muscles showed binding also in extrajunctional areas. After denervation there was also an increase in the junctional binding.
authors: Department of Neurology, Uppsala University, Sweden.
authors: H
authors: H
authors: Askmark
authors: P G
authors: PG
authors: Gillberg
mesh_terms: D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D001345:Autoradiography; D006614:Hindlimb; D008297:Male; D009121:Muscle Denervation; D009132:Muscles / Q000294:innervation / Q000378:metabolism*; D009469:Neuromuscular Junction / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011950:Receptors, Cholinergic / Q000378:metabolism*
chemical_list: D011950:Receptors, Cholinergic; D000109:Acetylcholine