Serum C-reactive protein concentrations in patients with pulmonary sarcoidosis.
In a prospective study serum C-reactive protein concentrations were measured in nine patients with "active" pulmonary sarcoidosis (as assessed by bronchoalveolar lavage lymphocyte counts, gallium-67 lung scanning, and serial pulmonary function testing), and in five patients with "inactive" disease. Active pulmonary sarcoidosis was associated either with no rise or with only a modest rise in serum C-reactive protein concentrations. In contrast, serum C-reactive protein concentrations in 12 patients with sputum positive pulmonary tuberculosis were considerably raised. Serum C-reactive protein may thus provide a valuable test in the differentiation of sarcoidosis from conditions which it may mimic and which are known to induce an acute phase response.
Hind
C R
CR
Department of Medicine, Middlesex Hospital, London.
Flint
K C
KC
Hudspith
B N
BN
Felmingham
D
D
Brostoff
J
J
Johnson
N M
NM
D000328:Adult; D002097:C-Reactive Protein / Q000032:analysis*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012507:Sarcoidosis / Q000097:blood*
D002097:C-Reactive Protein