[Quantitative characteristics of changes in the cellular composition and vascularization of aseptic wounds in rat skin, healing without treatment and during stimulation of repair processes by exogenous collagen].
The changes in cellular composition and vascularization of aseptic wounds on the rat skin were assessed quantitatively using the ocular net without treatment and during stimulation of repair processes by exogenous collagen. An intensive increase in the number of macrophages, endotheliocytes and fibroblasts was observed in wounds without treatment by the fifth day, with maximum vascularization of the granulation tissue occurring by the seventh day. During stimulation of repair processes by collagen the macrophage reaction, proliferation of endotheliocytes and fibroblasts and vascularization of wounds were activated earlier, while the stereotype relationships of the cellular components remained unchanged. The intercellular relationships of the wound healing process are discussed.
Berchenko
G N
GN
Berchenko
V V
VV
D000818:Animals; D001207:Asepsis; D003094:Collagen / Q000627:therapeutic use*; D006097:Granulation Tissue / Q000098:blood supply*; D008297:Male; D051381:Rats; D014945:Wound Healing / Q000187:drug effects*; D014947:Wounds and Injuries / Q000473:pathology* / Q000503:physiopathology
D003094:Collagen
Kolichestvennaia kharakteristika izmeneniia kletochnogo sostava i vaskuliarizatsii asepticheskikh ran kozhi krys, zazhivaiushchikh bez lecheniia i pri stimuliatsii reparativnykh protsessov éksogennym kollagenom.