The ultrastructure of normal fetal and neonatal pig testis germ cells and the influence of fetal decapitation on the germ cell development.
The development of germ cells in the male pig was investigated ultrastructurally in normal and decapitated fetuses. The age ranged respectively from 30 days p.c. till one month after birth and from 52 days p.c. until birth. The ultrastructural organization of the germ cells changes dramatically between 30 days p.c. and 52 days p.c. which coincides with the formation of 'true' sex cords. From 52 days p.c. onwards the morphology is rather stable: cells show a 'hydrated' appearance and typical cell bridges. There is no obvious difference in the ultrastructure of germ cells in decapitated animals, their normal littermates and control animals. Therefore germ cell development in the pig is likely to be insensitive to gonadotropins during the fetal period. The development of pig germ cells follows closely the pattern described for several species. Quantitatively there is an increase in the ratio of germ cell/Sertoli cell per cross sectional diameter in the decapitated animals.
van Vorstenbosch
C J
CJ
Department of Anatomy, School of Veterinary Medicine, Rijksuniversiteit Utrecht, The Netherlands.
Spek
E
E
Colenbrander
B
B
Wensing
C J
CJ
D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development*; D005854:Germ Cells / Q000648:ultrastructure*; D006062:Gonadotropins / Q000502:physiology*; D008297:Male; D008854:Microscopy, Electron; D012708:Sertoli Cells / Q000648:ultrastructure; D013552:Swine; D013737:Testis / Q000196:embryology / Q000254:growth & development* / Q000648:ultrastructure
D006062:Gonadotropins