title: Cardiopulmonary complications after major surgery: a role for epidural analgesia?
abstract: Improvement in postoperative pulmonary mechanics with epidural analgesia has been described. Data on the hemodynamic effects of this technique are absent from the surgical literature. To provide such data we have evaluated two groups of patients undergoing aortic reconstruction: group I (n = 25), general anesthesia and group II (n = 6), general anesthesia with adjunctive epidural analgesia. The groups were comparable preoperatively as judged by the incidence of cardiac history, preoperative ejection fraction, and measured hemodynamic parameters. Postoperatively there were no significant differences in the pressure-related parameters; however, rate-related factors including heart rate and double product were significantly decreased in group II with no reduction in cardiac index. Postoperative increases in total body oxygen consumption were also markedly attenuated by epidural analgesia. Epidural analgesia reduces the hemodynamic demands on the heart after major surgery and is a useful adjunct, especially in patients with coronary artery disease.
authors: Department of Surgery, Veterans Administration Medical Center, Detroit, Mich.
authors: L N
authors: LN
authors: Diebel
authors: M P
authors: MP
authors: Lange
authors: F
authors: F
authors: Schneider
authors: K
authors: K
authors: Mason
authors: R F
authors: RF
authors: Wilson
authors: L
authors: L
authors: Jacobs
authors: M S
authors: MS
authors: Dahn
mesh_terms: D000368:Aged; D000767:Anesthesia, Epidural; D000768:Anesthesia, General / Q000009:adverse effects; D001012:Aorta, Abdominal / Q000601:surgery; D001014:Aortic Aneurysm / Q000601:surgery; D001018:Aortic Diseases / Q000601:surgery*; D001157:Arterial Occlusive Diseases / Q000601:surgery; D001794:Blood Pressure; D002302:Cardiac Output; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D011669:Pulmonary Wedge Pressure; D013318:Stroke Volume