title: [Eremomycin--a new antibiotic from the cyclic glycopeptide group].
abstract: Eremomycin, a novel antibiotic belonging to the group of cyclic glycopeptides is produced by an actinomycete designated INA-238. Biosynthesis, isolation, physico-chemical and biological properties of the antibiotic are described. Eremomycin is shown to be close to vancomycin. However, by its chromatographic and electrophoretic mobility, presence of chlorine in the antibiotic molecule and optic characteristics eremomycin differs from vancomycin. Eremomycin is less toxic than vancomycin whereas its chemotherapeutic activity in treatment of infections caused by gram-positive organisms is higher.
authors: G F
authors: GF
authors: Gauze
authors: M G
authors: MG
authors: Brazhnikova
authors: A V
authors: AV
authors: Laĭko
authors: M A
authors: MA
authors: Sveshnikova
authors: T P
authors: TP
authors: Preobrazhenskaia
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000494:pharmacology / Q000633:toxicity; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005285:Fermentation; D051379:Mice; D008826:Microbial Sensitivity Tests; D008970:Molecular Weight; D013329:Structure-Activity Relationship; D014640:Vancomycin / Q000032:analysis / Q000494:pharmacology / Q000633:toxicity
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin
vernacular_title: Eremomitsin--novyĭ antibiotik iz gruppy tsiklicheskikh glikopeptidov.