Radiation therapy alone in the treatment of carcinoma of the uterine cervix: review of experience at Tokyo Women's Medical College (1969-1983).
Three hundred thirteen patients presented with squamous cell carcinoma of the uterine cervix at Tokyo Women's Medical College from 1969 to 1983. The results are presented here. All of the patients were treated by radiotherapy with curative intent with a combination of intracavitary cesium by low-dose rate, using T.A.O. afterloading applicators, which was made of flexible tubes to adapt to the physique of Japanese women by Tazaki, E., Arai, T. and Oryu, S. and external irradiation. One hundred and sixty patients (51.1%) presented with FIGO Stage III disease, 23 patients (7.3%) presented with Stage I disease, and 75 (24.0%) with Stage II. The 5-year cumulative survival rate was 81.7% for Stage I, 76.8% for Stage II, 53.3% for Stage III, 29.2% for Stage IVa, and 10.5% for Stage IVb, respectively. The overall 5-year survival rate was 55.8%. The local regional recurrence rate according to stage was 13.6% in Stage I, 22.4% in Stage II, 41.3% in Stage IIII, and 46.7% in Stage IVa. The incidence of locoregional recurrence rate was 35.6% and distant metastasis 37.8%. The incidence of complications involving bleeding and pain which required hospitalization, was 12.2% in all patients. Only four required surgery to manage serious complications.
Okawa
T
T
Dept. of Radiology, Tokyo Women's Medical College, Japan.
Kita
M
M
Goto
M
M
Tazaki
E
E
D001918:Brachytherapy; D002277:Carcinoma / Q000532:radiotherapy*; D005260:Female; D009364:Neoplasm Recurrence, Local; D011878:Radiotherapy / Q000009:adverse effects; D012002:Rectal Diseases / Q000209:etiology; D013997:Time Factors; D001745:Urinary Bladder Diseases / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*