Cholecystectomy with highly selective vagotomy--the effect on bile reflux. An experimental study.
An experimental study investigated the effect of highly selective vagotomy (HSV) alone and HSV combined with cholecystectomy on bile reflux into the stomach. The amount of reflux was estimated by measuring the concentration of bile phospholipids in the stomach. Neither HSV alone nor HSV combined with cholecystectomy was associated with increased reflux. In fact HSV seems to prevent reflux and inhibit the production of lysolecithin, which is injurious to the gastric mucosa.
Demetriades
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Department of Surgery, University of the Witwatersrand, Johannesburg.
Beale
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D000818:Animals; D001655:Bile Reflux / Q000601:surgery*; D001660:Biliary Tract Diseases / Q000601:surgery*; D002763:Cholecystectomy; D004285:Dogs; D005766:Gastrointestinal Contents / Q000032:analysis; D008244:Lysophosphatidylcholines / Q000032:analysis; D010713:Phosphatidylcholines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis; D014629:Vagotomy, Proximal Gastric
D008244:Lysophosphatidylcholines; D010713:Phosphatidylcholines; D010743:Phospholipids