title: A simplified thin-layer chromatography system for the detection of commonly abused basic drugs.
abstract: A simple method for the detection of drugs of abuse and their metabolites in urine is described. By extraction of urine (20 mL) with a buffered ToxElut solid phase column all the commonly abused opioid drugs can be detected on a single thin-layer chromatography plate. Location of the spots is achieved by spraying the plate with iodoplatinate following acidification with dilute sulphuric acid. Sensitivity of the order of 1 mg/L is attained for most drugs.
authors: Department of Analytical Pharmacology, Ealing Hospital, Southall, Middlesex, UK.
authors: J
authors: J
authors: Blakesley
authors: D
authors: D
authors: Wood
authors: C
authors: C
authors: Howse
authors: J
authors: J
authors: Spencer-Peet
mesh_terms: D002855:Chromatography, Thin Layer / Q000379:methods; D006801:Humans; D013287:Illicit Drugs / Q000652:urine*; D009294:Narcotics / Q000652:urine*
chemical_list: D013287:Illicit Drugs; D009294:Narcotics