title: Bovine haemoglobin beta A Zebu, beta A43(CD3)Ser----Thr: an intermediate globin type between the beta A and beta D Zambia is present in Indian zebu cattle.
abstract: Two bovine haemoglobin beta chains, electrophoretically identical with the beta A chain of Herefords, were obtained from Ongole and Banteng, Bos javanicus, cattle. The amino acid residue differences of the two beta chains were compared by electrophoresis, cation-exchange and reverse-phase chromatography, amino acid analyses, and Edman degradation in comparison with beta A chain. The results showed that two beta chains differed from the beta A chain of the Hereford breed by the substitution of serine with threonine at the beta 43 position. No other difference was found between the two chains and beta A. This new beta chain type was termed beta A Zebu, which forms a possible evolutionarily transitional type between the beta A and the rare variant beta D Zambia found previously in African zebu cattle. The beta A Zebu differentiates from the previous beta B by at least four amino acid substitutions involving five codon-base changes.
authors: Laboratory of Animal Genetics, Faculty of Agriculture, Nagoya University, Japan.
authors: T
authors: T
authors: Namikawa
authors: A
authors: A
authors: Nagai
authors: O
authors: O
authors: Takenaka
authors: A
authors: A
authors: Takenaka
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D005075:Biological Evolution; D002417:Cattle / Q000235:genetics*; D006454:Hemoglobins / Q000235:genetics; D007194:India; D010641:Phenotype; D015024:Zambia
chemical_list: D000596:Amino Acids; D006454:Hemoglobins