Low LH receptor content in corpora lutea in luteinized unruptured follicle (LUF) syndrome.
Concentrations of LH receptors in ovarian corpora lutea were measured in four women with ultrasonically monitored cycles, [in which luteinized unruptured follicles (LUF) were observed] and in one woman with an LUF observed during laparotomy. LH receptor concentrations were also measured in four control patients with proven fertility. The LH receptor concentrations in cases of LUF syndrome were on average 60% lower (P less than 0.01) than in the control patients. These results suggest that in LUF patients there is a disorder in the mechanism of LH action in the developing follicles.
Koskimies
A I
AI
Department Obstetrics and Gynaecology, Helsinki University Central Hospital, Finland.
Liukkonen
S
S
Tenhunen
A
A
Huhtaniemi
I
I
D000328:Adult; D006063:Chorionic Gonadotropin / Q000378:metabolism; D003338:Corpus Luteum / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000378:metabolism*; D008875:Middle Aged; D006080:Ovarian Follicle / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism; D011974:Receptors, LH / Q000378:metabolism*; D013577:Syndrome
D006063:Chorionic Gonadotropin; D011974:Receptors, LH; D011374:Progesterone; D004958:Estradiol