Electrophysiological study of synaptic connections between a transplanted lateral geniculate nucleus and the visual cortex of the host rat.
The lateral geniculate nucleus (LGN) of a fetal rat was transplanted to the visual cortex (VC) of a neonatal rat. A current source-density analysis of field potentials and an intracellular study of neuronal responses were conducted in slice preparations by electrical stimulation of transplanted LGN and host VC. The results indicated that synaptic connections were established reciprocally between the transplanted LGN and the host VC.
Hamasaki
T
T
Department of Neurosurgery, Kyoto Prefectural University of Medicine, Japan.
Komatsu
Y
Y
Yamamoto
N
N
Nakajima
S
S
Hirakawa
K
K
Toyama
K
K
D000200:Action Potentials; D000818:Animals; D004558:Electric Stimulation; D005829:Geniculate Bodies / Q000502:physiology / Q000637:transplantation* / Q000648:ultrastructure; D066298:In Vitro Techniques; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000502:physiology* / Q000648:ultrastructure; D014793:Visual Cortex / Q000502:physiology*