A genetic study of Behçet's disease in Taiwan Chinese.
The frequency of HLA-A, B and C antigen in 53 patients and HLA-DR, DQ and Dn antigen in 31 patients of Behçet's disease was studied. All patients were Chinese, and diagnosis was made according to the Japanese Research Committee on Behçet's disease. A significantly increased incidence of HLA-B51 (P less than 0.001) and a significantly decreased incidence of HLA-B16 (P less than 0.01) was found. No significant difference was found in HLA-DR, DQ and DN antigens.
Chung
Y M
YM
Department of Ophthalmology, National Yang-Ming Medical College, Taipei, Taiwan, Republic of China.
Tsai
S T
ST
Liao
F
F
Liu
J H
JH
D001528:Behcet Syndrome / Q000235:genetics*; D004198:Disease Susceptibility; D005260:Female; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D006681:HLA-D Antigens / Q000235:genetics*; D006683:HLA-DQ Antigens / Q000235:genetics; D006684:HLA-DR Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D013624:Taiwan
D006680:HLA Antigens; D006681:HLA-D Antigens; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens