title: The distal splenorenal shunt: an update on experience of 106 cases.
abstract: This paper analyzes experience with 106 patients treated primarily with DSRS during a ten year period. Operative mortality was 5% of cases. Shunt patency was evaluated by postoperative angiography in 70 patients. A shunt thrombosis and a recanalization of the splenic vein were noted in a patient who had a Britton's operation resulting in a side-to-side shunt. In the other 31 cases, shunt patency was indirectly confirmed by the absence of varices at postoperative or long-term endoscopic examination. At postoperative check, esophageal varices had disappeared in only 19% of patients. However, this rose to 60% at long-term check-up. Ten patients bled from varices in the postoperative period (9%). During the follow-up period, no patient bled from varices, while five patients bled from gastroduodenal lesions (5%). During the postoperative period, 52% of cases had ascites. In the long-term, ascites developed in only 15% of cases and was well controlled by standard medical treatment. Analysis of the actuarial curve showed a 5-year survival rate of 63%. During the follow-up period, 17% of patients experienced at least one episode of acute encephalopathy. Chronic encephalopathy appeared in 14% of cases: ten patients suffered a mild form (10%) and four (4%) a moderate form. No patient had severe chronic encephalopathy. DSRS is effective as treatment of portal hypertension with a low long-term morbidity despite a more troublesome early postoperative period.
authors: Institute of 1st Surgical Clinic, University of Milan, Italy.
authors: G
authors: G
authors: Pezzuoli
authors: G
authors: G
authors: Spina
authors: R
authors: R
authors: Santambrogio
authors: F
authors: F
authors: Galeotti
authors: E
authors: E
authors: Opocher
authors: G
authors: G
authors: Cucchiaro
authors: C
authors: C
authors: Lopez
authors: M
authors: M
authors: Strinna
mesh_terms: D000206:Actuarial Analysis; D004932:Esophageal and Gastric Varices / Q000453:epidemiology; D005069:Evaluation Studies as Topic; D005260:Female; D006501:Hepatic Encephalopathy / Q000453:epidemiology; D006801:Humans; D006975:Hypertension, Portal / Q000601:surgery*; D008103:Liver Cirrhosis / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D013164:Splenorenal Shunt, Surgical / Q000009:adverse effects / Q000401:mortality; D014654:Vascular Patency