title: Exercise-induced pulmonary haemorrhage in the horse: results of a detailed clinical, post mortem and imaging study. II. Gross lung pathology.
abstract: Gross post mortem examinations were performed on the lungs of 26 Thoroughbred horses of known exercise-induced pulmonary haemorrhage (EIPH) status. The most consistent finding was a variable degree of bilaterally symmetrical, dark discolouration of the dorsocaudal regions of the caudal lung lobes. In more severely affected lungs, the stained areas extended cranially along the dorsal surfaces of the lungs, and in some cases affected approximately one third of the lung surface. Discoloured areas of lung were denser than normal, collapsed less readily, often contained trapped air and were slow to inflate. The subpleural bronchial arteries were more prominent in the discoloured regions. Pleural adhesions were noted in two horses but were not related to the discoloured lung regions. It was concluded that the discoloured lesions have a complex pathogenesis and were related directly to previous bouts of EIPH. Associated with them were signs indicating probable partial small airway obstruction, decreased tissue compliance and direct involvement of the bronchial arterial circulation.
authors: Department of Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616.
authors: M W
authors: MW
authors: O'Callaghan
authors: J R
authors: JR
authors: Pascoe
authors: W S
authors: WS
authors: Tyler
authors: D K
authors: DK
authors: Mason
mesh_terms: D000818:Animals; D006470:Hemorrhage / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D008168:Lung / Q000473:pathology*; D008171:Lung Diseases / Q000473:pathology / Q000662:veterinary*; D008297:Male; D005082:Physical Exertion