Competition between adsorbed fibrinogen and high-molecular-weight kininogen on solid surfaces incubated in human plasma (the Vroman effect): influence of solid surface wettability.
The influence of the surface energy on the competition between fibrinogen and high-molecular-weight kininogen has been studied with the use of a recently described wettability gradient method. One finding is that the decrease in the antifibrinogen binding on plasma incubated gradient surfaces was not associated with an increase in anti-HMWK binding at all parts of the gradient surfaces.
Elwing
H
H
Department of Physics and Measurement Technology, Linköping Institute of Technology, Sweden.
Askendal
A
A
Lundström
I
I
D000327:Adsorption; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D007704:Kininogens / Q000378:metabolism*; D008970:Molecular Weight; D010949:Plasma; D012825:Silicon; D013499:Surface Properties; D014867:Water
D007704:Kininogens; D014867:Water; D005340:Fibrinogen; D012825:Silicon