title: Increase in life expectancy for mice fed diethylhydroxylamine (DEHA).
abstract: ICR Swiss strain mice were fed diethylhydroxylamine (DEHA) for life starting at 44 days of age at 10, 30, 100, and 300 mg/kg-day. The 10 and 30 mg/kg-day males and the 10 mg/kg-day females showed an increase in mean age of death of 76 (12.7%), 45 (7.5%), and 51 (7.4%) days, respectively, compared to controls. The respective confidence levels are 99.2, 90.0, and 92.9% that these results are significant by Student's t test.
authors: Department of Chemistry, Pennsylvania State University.
authors: J
authors: J
authors: Heicklen
authors: E
authors: E
authors: Brown
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004326:Drinking / Q000187:drug effects; D005260:Female; D006898:Hydroxylamines / Q000494:pharmacology*; D008017:Life Expectancy; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009026:Mortality; D011897:Random Allocation; D013268:Stimulation, Chemical; D013934:Thymectomy
chemical_list: D006898:Hydroxylamines; C033314:N,N-diethylhydroxylamine