[Morphofunctional characteristics of the thyroid gland in intact and partially sympathectomized rats of different age groups].
The morphological and functional age-dependent changes have been studied in the thyroid gland of infantile (1-month-old), immature (2- and 3-month-old) and sexually mature (6-month-old) male rats. The decrease in thyroid functional activity with ageing was proved. Chemical sympathectomy (guanethidine at a dose of 15 mg/kg intramuscularly for 14 days after birth) was accompanied not only by morphological reconstruction of the thyroid tissue, but also (especially in 1-month-old rats) by a delay in transport-organic phase of iodine metabolism and a decline in thyroid hormone serum level. Later on, the compensatory hormonogenesis reinforcement occurs as a result of partial adrenergic innervation recovery.
Riashchikov
S N
SN
Glumova
V A
VA
Markov
V N
VN
Zelenin
A A
AA
D000375:Aging / Q000502:physiology*; D000818:Animals; D008297:Male; D051381:Rats; D013563:Sympathectomy, Chemical; D013564:Sympathetic Nervous System / Q000502:physiology*; D013961:Thyroid Gland / Q000166:cytology / Q000502:physiology*; D013963:Thyroid Hormones / Q000097:blood
D013963:Thyroid Hormones
Morfofunktsional'naia kharakteristika shchitovidnoĭ zhelezy intaktnykh i chastichno desimpatizirovannykh krys raznykh vozrastnykh grupp.