[The course of renal function in vesicorenal reflux. Study using I-123 Hippuran].
Fifty-two patients with vesicoureteral reflux (age: 6.4 +/- 6.2 years) were examined by IVP, voiding cystouretrography and 123 I-Hippuran studies. 17 patients were not operated; 26 had an antireflux, 9 an urethral surgery. The follow-up was 2 years for 39 of these patients, with at least one evaluation per year. The observations were: Unoperated patients were younger, had a lower radiological grade of reflux and renal functional impairment was less frequent. Functional impairment was initially equally distributed in unilateral (53%) and bilateral (54%) reflux. Radiological grade of reflux had an unsatisfactory predictive value for functional renal status. Functional renal status at 2 years was unchanged in 82% of patients. Improvement was observed in 8%, deterioration in 10%. These results were not influenced by the choice of treatment. However, reflux persistence was more frequently observed in the un-operated group (50% versus 5%). Renal transit times of 123 I-Hippuran did not correlate with the functional status or the radiological grade of reflux.
Simon
J
J
Service d'Urologie, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Belgique.
Schoutens
A
A
Thirion
M
M
Schulman
C
C
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007465:Iodohippuric Acid; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D014718:Vesico-Ureteral Reflux / Q000188:drug therapy / Q000503:physiopathology* / Q000601:surgery
D007465:Iodohippuric Acid
Evolution de la fonction rénale en présence de reflux vésico-rénal. Etude par l'123 I-Hippuran.