Ionostatic control of food intake in the domestic fowl.
It has been suggested that there is ionostatic control of food intake in which calcium, acting in the hypothalamus, alters food intake. This study was conducted to determine the effects of intracerebroventricular (ICV) injections of calcium on food and water intake in both broiler and Leghorn cockerels. The ICV injection of 50, 100, or 150 mM CaCl2 had no significant affect on food or water intake in Leghorn cockerels. In broilers, the ICV injection of 50 mM CaCl2 significantly increased food intake. This effect appeared to be due to Ca++ as equivalent amounts of Cl- given as NaCl had no effect on food intake nor did isosmotic solutions of NaCl. The effect of Ca++ on water intake in broilers is equivocal as it increased water intake in one experiment while decreasing it in another. Whereas these results support the hypothesis of a role for calcium in food intake regulation in broilers, they do not support the existence of a specific ionostatic control mechanism.
Denbow
D M
DM
Department of Poultry Science, Virginia Polytechnic Institute and State University, Blacksburg 24061.
Van Krey
H P
HP
D000818:Animals; D002122:Calcium Chloride / Q000008:administration & dosage / Q000494:pharmacology*; D002645:Chickens / Q000502:physiology*; D004326:Drinking / Q000187:drug effects*; D004435:Eating / Q000187:drug effects*; D007031:Hypothalamus / Q000187:drug effects*; D007276:Injections, Intraventricular; D008297:Male
D002122:Calcium Chloride