A myelodysplastic syndrome with eosinophilia associated with a break in the short arm of chromosome 16.
A case is reported of a young man with cardiomyopathy and myelodysplasia with bone marrow and peripheral blood eosinophilia. Cytogenetic investigation revealed a (5;16) (q33;p13) translocation. This is the first report of myelodysplasia with eosinophilia associated with a break in 16p13 alone, with no abnormality of 16q22.
Ross
F M
FM
MRC Clinical and Population Cytogenetics Unit, Western General Hospital, Edinburgh.
Hamilton
M
M
Cook
M K
MK
Irving
J B
JB
D000328:Adult; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002885:Chromosomes, Human, Pair 16; D004802:Eosinophilia / Q000150:complications* / Q000235:genetics; D006331:Heart Diseases / Q000209:etiology; D006801:Humans; D007621:Karyotyping; D008297:Male; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000235:genetics