title: The primary structure of the hemoglobin of spectacled bear (Tremarctos ornatus, Carnivora).
abstract: The complete primary structure of the alpha- and beta-chains of the hemoglobin of Spectacled Bear (Tremarctos ornatus) is presented. Following cleavage of the heme-protein link and chain separation by RP-HPLC, their amino-acid sequences were determined by Edman degradation in liquid- and gas-phase sequenators. The hemoglobin of Spectacled Bear displays only five amino-acid exchanges to that of Polar Bear (Ursus maritimus, Ursinae) and Asiatic Black Bear (Ursus tibetanus, Ursinae) whereas 8 and 12 replacements, respectively, to Giant Panda (Ailuropoda melanoleuca) and Lesser Panda (Ailurus fulgens) can be found. This clearly demonstrates that the Spectacled Bear, the most aberrant bear of the Ursidae, is somewhat intermediate between Pandas and Ursinae.
authors: Max-Planck-Institut für Biochemie, Abt. Proteinchemie, Martinsried bei München.
authors: O
authors: O
authors: Hofmann
authors: G
authors: G
authors: Braunitzer
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D005075:Biological Evolution; D002335:Carnivora / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D006454:Hemoglobins / Q000032:analysis*; D008969:Molecular Sequence Data; D013045:Species Specificity; D001503:Ursidae / Q000097:blood*
chemical_list: D000596:Amino Acids; D006454:Hemoglobins