title: Effect of levodopa treatment on contrast sensitivity in Parkinson's disease.
abstract: We studied contrast sensitivity function in 10 parkinsonian patients before and after levodopa treatment. Pretreatment contrast sensitivity function was abnormal in 16 of the 20 eyes. After treatment, only high-frequency loss was observed in 6 eyes. All other types of deficit disappeared under treatment. These changes of contrast sensitivity function following treatment suggest that dopamine is a functional transmitter in the visual pathways.
authors: Department of Neurology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands.
authors: C
authors: C
authors: Bulens
authors: J D
authors: JD
authors: Meerwaldt
authors: G J
authors: GJ
authors: Van der Wildt
authors: J B
authors: JB
authors: Van Deursen
mesh_terms: D000368:Aged; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy* / Q000503:physiopathology; D014787:Vision Tests; D014785:Vision, Ocular / Q000187:drug effects*
chemical_list: D007980:Levodopa