Nephrotoxic activity in rats fed diets containing DL-3-(N-phenylethylamino)-alanine.
Rats were fed DL-3-(N-phenylethalamino)-alanine which resulted in kidney lesions histologically identical with those produced by the structurally related compound lysinoalanine. Possible mechanisms for nephrotoxicity are discussed.
Jones
G P
GP
School of Sciences, Deakin University, Vic.
Hooper
P T
PT
Rivett
D E
DE
Tucker
D J
DJ
Lambert
G
G
Billett
A
A
D000284:Administration, Oral; D000818:Animals; D004032:Diet; D007274:Injections, Intraperitoneal; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D008297:Male; D010627:Phenethylamines / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains
D010627:Phenethylamines; C050457:3-((2-phenylethyl)amino)alanine