title: Radionuclide transit in patients with colon interposition.
abstract: To assess radionuclide transit in interposed segments of the colon, we examined 25 patients with colon interposition for benign esophageal disease. No such assessment has been reported previously. The most common indications for operation were esophageal strictures that developed after lye ingestion and reflux strictures not responding to other treatment. The operations were performed without thoracotomy by blunt esophageal dissection in 80% of the patients. There were 18 antiperistaltic and seven isoperistaltic colon grafts. A large-field gamma camera and computer system were used. Data were collected at time intervals of 0.5 second during the first 30 seconds and at intervals of 30 seconds up to 20 minutes. The 5% and 90% stomach filling times, times to 50% and 25% activity levels, and residual activity levels as a percentage of the maxima were calculated in the upper, middle, and lower thirds of the colon grafts and of the normal esophagus of 10 healthy control subjects. The examinations were performed with the subject in a sitting position. All parameters showed that emptying of the colon graft was markedly slower than that of the normal esophagus. The intra-abdominal third of the graft had a residual activity of 50.5% +/- 15.7% after 20 minutes' observation. No differences between antiperistaltic and isoperistaltic grafts were observed. Reconstruction with proximal cologastric anastomosis and a short intra-abdominal colon graft segments is suggested.
authors: Department of Surgery, Tampere University Central Hospital, Finland.
authors: J
authors: J
authors: Isolauri
authors: M O
authors: MO
authors: Koskinen
authors: H
authors: H
authors: Markkula
mesh_terms: D000328:Adult; D000368:Aged; D003106:Colon / Q000601:surgery*; D004935:Esophageal Diseases / Q000601:surgery; D004944:Esophagoplasty; D005069:Evaluation Studies as Topic; D005260:Female; D005764:Gastroesophageal Reflux / Q000000981:diagnostic imaging / Q000209:etiology; D005772:Gastrointestinal Transit; D006801:Humans; D008297:Male; D008875:Middle Aged; D010528:Peristalsis; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011187:Posture; D011877:Radionuclide Imaging; D013667:Technetium; D017556:Technetium Compounds; D013997:Time Factors; D014001:Tin; D017971:Tin Compounds
chemical_list: D017556:Technetium Compounds; D017971:Tin Compounds; C033493:technetium Tc 99m tin colloid; D013667:Technetium; D014001:Tin