Localization of MIC5 to the region between HPRT and G6PD on the human X chromosome.
The X-linked gene, MIC5, encodes a human cell-surface antigen, R1. We have assigned MIC5 to the region between HPRT and G6PD on the long arm of the X chromosome. Regional localization was based on the pattern of reactivity of the R1 monoclonal antibody with human-rodent somatic cell hybrids which contained different fragments of the human X chromosome.
Hope
R
R
Department of Genetics, University of Adelaide, South Australia.
Goss
S
S
Solomon
E
E
Ropers
H H
HH
Banting
G
G
Goodfellow
P N
PN
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000032:analysis / Q000235:genetics*; D002460:Cell Line; D002874:Chromosome Mapping; D002999:Clone Cells; D008040:Genetic Linkage; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics; D006801:Humans; D006822:Hybrid Cells; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics; D011863:Radioimmunoassay; D014960:X Chromosome
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface; D005954:Glucosephosphate Dehydrogenase; D007041:Hypoxanthine Phosphoribosyltransferase