Antibiotic serum activities against bacterial isolations from cases of bovine pneumonic pasteurellosis in feedlot calves.
The serum bactericidal activity test was carried out in two groups of 7 calves each suspected to be suffering from pneumonic pasteurellosis. The diagnosis was based on clinical signs, endoscopic examination and bacteriological investigations. The first group of seven calves received oxytetracycline at a dosage rate of 10 mg kg-1 once a day. A second similar group received penicillin at 30,000 IU kg-1 once a day. Results showed that the correlation between antibiograms, serum bactericidal activity and clinical response may be good for oxytetracyclines and poor for penicillin. The serum bactericidal activity test may be a good method to establish effective dosages for certain antibiotics in the treatment of pneumonic pasteurellosis.
Van Amstel
S R
SR
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Republic of South Africa.
Witcomb
M A
MA
Fabian
B
B
Vervoort
P
P
D000818:Animals; D002415:Cats; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D010118:Oxytetracycline / Q000008:administration & dosage* / Q000097:blood; D010325:Pasteurella / Q000187:drug effects*; D010326:Pasteurella Infections / Q000188:drug therapy / Q000662:veterinary*; D010406:Penicillins / Q000008:administration & dosage* / Q000097:blood; D011014:Pneumonia / Q000188:drug therapy / Q000662:veterinary*
D010406:Penicillins; D010118:Oxytetracycline