[Non-immunologic hydrops fetalis (NIHF)--case report of double partial trisomy 15q and 17q resulting from familial translocation 15/17 and cytogenetic findings in 50 cases with hydrops fetalis].
We report the first case of non-immune hydrops fetalis (NIHF) with trisomy 15q11/17q22.5 resulting from a familial translocation 15/17. Furthermore the cytogenetic findings of 50 cases with hydrops fetalis are presented. Of the 30 cytogenetic analyzable cases 7 showed chromosomal abnormalities (4x45,X; 2x47,XY,+21; 1x47,XY,+13). In every case of NIHF a chromosomal analysis should be performed if possible from different tissues.
Schmid
G
G
Universitäts-Kinderklinik Bonn.
Haverkamp
F
F
Rechmann
J
J
Schwanitz
G
G
Zerres
K
K
Hansmann
M
M
Kowalewski
S
S
D002884:Chromosomes, Human, Pair 15; D002886:Chromosomes, Human, Pair 17; D004487:Edema / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000235:genetics*; D007621:Karyotyping; D008297:Male; D010375:Pedigree; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014178:Translocation, Genetic; D014314:Trisomy
Nicht-immunologischer Hydrops fetalis (NIHF)--Falldarstellung einer doppelten partiellen Trisomie 15q und 17q infolge einer familiären Translokation 15/17 und zytogenetische Befunde bei 50 Fällen mit Hydrops fetalis.