Hypercholinesterasaemia and suxamethonium resistance.
A case is reported of resistance to the muscle relaxing action of suxamethonium due to the rare inherited condition of hypercholinesterasaemia. Family studies suggest dominant inheritance. It is suggested the condition should be considered whenever there is unexpected resistance to the muscle relaxing action of suxamethonium.
Warran
P
P
King Khalid Hospital, Jeddah.
Theeman
M
M
Bold
A M
AM
Jones
S
S
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002802:Cholinesterases / Q000097:blood* / Q000235:genetics; D004351:Drug Resistance / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013390:Succinylcholine / Q000494:pharmacology*
D002802:Cholinesterases; D013390:Succinylcholine