title: Haptoglobin patterns in essential hypertension and associated conditions--increased risk for Hp 2-2.
abstract: Blood samples from 257 hypertensive patients and 180 normotensive controls were analysed for their association with haptoglobin levels and phenotypes. Compared to controls, patients with Hp 2-2 phenotype showed a significantly increased risk for essential hypertension (p less than 0.001) and hypertension associated with ischaemic heart disease (p less than 0.05). There was a significant decrease in the mean levels of serum haptoglobins in hypertension as compared to controls, suggesting the possibility for intravascular haemolysis due to vascular damage leading to further complications.
authors: Department of Genetics, Osmania University, Hyderabad, India.
authors: P
authors: P
authors: Surya Prabha
authors: T
authors: T
authors: Padma
authors: M
authors: M
authors: Ramaswamy
mesh_terms: D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood; D006242:Haptoglobins / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000097:blood*; D009203:Myocardial Infarction / Q000097:blood / Q000150:complications; D010641:Phenotype; D012306:Risk
chemical_list: D006242:Haptoglobins