Screening for osteomalacia in elderly patients with femoral neck fractures.
In this study 201 elderly patients with femoral neck fractures were compared with 30 osteomalacic patients with the same injury. Hypocalcaemia and a raised alkaline phosphatase level are common biochemical abnormalities in elderly patients with femoral neck fractures. In only a minority of patients, however, were they associated with histologically proven osteomalacia. By using the combination of hypocalcaemia and a raised alkaline phosphatase it is possible to identify a subgroup (approximately 10% of all admissions) in whom osteomalacia is relatively likely.
Wilton
T J
TJ
Department of Orthopaedic Surgery, University Hospital, Queen's Medical Centre, Nottingham, England.
Hosking
D J
DJ
Pawley
E
E
Stevens
A
A
Harvey
L
L
D000368:Aged; D000369:Aged, 80 and over; D000469:Alkaline Phosphatase / Q000097:blood; D002118:Calcium / Q000097:blood; D004796:Clinical Enzyme Tests; D003404:Creatinine / Q000097:blood; D004739:England; D005260:Female; D005265:Femoral Neck Fractures / Q000097:blood / Q000150:complications*; D006801:Humans; D006996:Hypocalcemia / Q000097:blood; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D010018:Osteomalacia / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*
D003404:Creatinine; D000469:Alkaline Phosphatase; D002118:Calcium