Differentiation of F38 mycoplasmas causing contagious caprine pleuropneumonia with a growth-inhibiting monoclonal antibody.
Monoclonal antibody WM-25 inhibited the in vitro growth of 13 F38 isolates from goats with contagious caprine pleuropneumonia but not 7 heterologous mycoplasma isolates representing four different species. In contrast to results with polyclonal antisera, growth inhibition by monoclonal antibody WM-25 was specific for F38 mycoplasma isolates and constituted a reliable means of distinguishing F38 from other mycoplasmas.
Rurangirwa
F R
FR
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman 99164.
McGuire
T C
TC
Musoke
A J
AJ
Kibor
A
A
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D006041:Goats / Q000382:microbiology*; D009174:Mycoplasma / Q000254:growth & development / Q000276:immunology*; D011019:Pneumonia, Mycoplasma / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*
D000911:Antibodies, Monoclonal