title: Neonatal pharyngoesophageal perforation mimicking esophageal atresia: clues to diagnosis.
abstract: Perforation of the newborn child's esophagus or pharynx can mimic esophageal atresia clinically. Fourteen cases of newborn hypopharyngeal or esophageal perforation are presented. In nine cases, esophageal atresia was the initial diagnosis entertained; seven of these on the first day of life. In four others, the diagnosis of a perforated pharynx or esophagus was evident on plain x-ray. Six patients had esophagograms. Two newborns underwent thoracotomies for repair of their initially diagnosed esophageal atresia. Subsequently, esophageal perforation was diagnosed intraoperatively on each and suture repair was undertaken. The 12 remaining neonates were treated nonoperatively. There were four deaths, all in the nonoperative group and three weighing less than 1,000 g. None of the deaths were directly attributable to the perforations. In retrospect, each child presented with one or more early clues to the diagnosis of pharyngoesophageal perforation, which included a history of difficult tracheal or nasogastric intubation, blood in the nasogastric tube, length and course of nasogastric tube inserted, and subtle chest x-ray changes. In these cases, nonoperative treatment is usually successful.
authors: Hospital for Sick Children, Toronto, Ontario, Canada.
authors: G K
authors: GK
authors: Blair
authors: R M
authors: RM
authors: Filler
authors: D
authors: D
authors: Theodorescu
mesh_terms: D003937:Diagnosis, Differential; D004933:Esophageal Atresia / Q000175:diagnosis*; D004939:Esophageal Perforation / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D010614:Pharynx / Q000000981:diagnostic imaging / Q000293:injuries*; D011859:Radiography