[Oxygen requirements of the arterial and venous walls after cholesterol administration to animals].
An experimental study in rabbits examined the intensity of oxygen consumption by strips of thoracic and abdominal aortas, pulmonary and common carotid arteries, posterior caval and portal veins after 5, 15, 30, 60 and 120 days of cholesterol feeding. A biphasic pattern of changes was demonstrated in oxygen consumption by the vascular wall under experimental atherosclerosis. An increase in Qo2 was followed by a decrease of the intensity of oxygen consumption. The duration and magnitude of each phase was dependent on baseline oxygen consumption by the vascular wall, on total duration of cholesterol feeding and the doses administered.
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D000818:Animals; D001808:Blood Vessels / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000008:administration & dosage / Q000378:metabolism*; D005260:Female; D008297:Male; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D011817:Rabbits
D002791:Cholesterol, Dietary
Potreblenie kisloroda arterial'noĭ i venoznoĭ stenkoĭ v usloviiakh vvedeniia zhivotnym kholesterina.