Aluminum accumulation in children on chronic dialysis: predictive value of serum aluminum levels and desferrioxamine infusion test.
In 7 children on chronic dialysis the correlation between serum aluminum, aluminum after desferrioxamine (DFO) challenge and bone aluminum was studied. In children the DFO challenge test is not superior to the serum aluminum level for the estimation of aluminum body burden. A significant correlation between serum aluminum and bone aluminum content was found. In all children, except one, aluminum bone content was markedly elevated.
Roodhooft
A M
AM
Department of Pediatrics, University of Antwerp, Belgium.
van de Vyver
F L
FL
D'Haese
P C
PC
van Acker
K J
KJ
Visser
W J
WJ
de Broe
M E
ME
D000293:Adolescent; D000535:Aluminum / Q000097:blood*; D001842:Bone and Bones / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D003676:Deferoxamine; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008297:Male; D010530:Peritoneal Dialysis; D006435:Renal Dialysis
D000535:Aluminum; D003676:Deferoxamine