Determination of cocaine in human hair by gas chromatography/mass spectrometry.
A qualitative method for the determination of cocaine alone without its metabolites in human hair by gas chromatography/mass spectrometry (GC/MS) was developed. The assay used helium as carrier gas, a 30-m bonded phase fused silica OV-1 capillary column, and solid injection at 290 degrees C evaporator temperature. The cocaine concentrations in hair were determined also by radioimmunoassay (RIA). The values obtained are the sum of cocaine and its metabolites. Both GC/MS and RIA meet the requirements for the determination of drug abuse by two different methods in forensic science.
Balabanova
S
S
Department of Forensic Medicine, University of Ulm, Federal Republic of Germany.
Homoki
J
J
D000818:Animals; D003042:Cocaine / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006197:Hair / Q000032:analysis*; D006801:Humans; D011863:Radioimmunoassay; D012756:Sheep; D019966:Substance-Related Disorders / Q000175:diagnosis*
D003042:Cocaine