In vitro conversion of pyrazinamide into 5-hydroxypyrazinamide and that of pyrazinoic acid into 5-hydroxypyrazinoic acid by xanthine oxidase from human liver.
Yamamoto
T
T
Third Department of Internal Medicine, Hyogo College of Medicine, Japan.
Moriwaki
Y
Y
Takahashi
S
S
Hada
T
T
Higashino
K
K
D006801:Humans; D008099:Liver / Q000201:enzymology*; D009243:NAD / Q000494:pharmacology; D011718:Pyrazinamide / Q000031:analogs & derivatives* / Q000378:metabolism*; D014969:Xanthine Oxidase / Q000494:pharmacology*
D009243:NAD; C032191:5-hydroxypyrazinamide; D011718:Pyrazinamide; C005296:pyrazinoic acid; D014969:Xanthine Oxidase