title: Scleromyxedema with corneal deposits.
abstract: Scleromyxedema (Arndt-Gottron syndrome) is a rare cutaneous disease in which hyaluronic acid is deposited in the dermis. The authors describe a patient with scleromyxedema and corneal deposits. A corneal biopsy demonstrated hyaluronic acid deposition in the corneal stroma and amyloid P component in Bowman's membrane. This is the first report of scleromyxedema involving the cornea. It is also the first report of amyloid P component deposition in the cornea occurring independent of corneal amyloid deposits.
authors: Department of Medicine, Cook County Hospital, Chicago, IL 60612.
authors: H M
authors: HM
authors: Goldin
authors: A J
authors: AJ
authors: Axelrod
authors: D M
authors: DM
authors: Bronson
authors: E
authors: E
authors: Torczynski
authors: C M
authors: CM
authors: Arroyave
authors: S
authors: S
authors: Barsky
mesh_terms: D000328:Adult; D001706:Biopsy; D003315:Cornea / Q000473:pathology; D003318:Corneal Opacity / Q000473:pathology*; D003319:Corneal Stroma / Q000473:pathology; D006801:Humans; D006820:Hyaluronic Acid / Q000378:metabolism; D008297:Male; D009230:Myxedema / Q000473:pathology*; D000683:Serum Amyloid P-Component / Q000378:metabolism; D012867:Skin / Q000473:pathology
chemical_list: D000683:Serum Amyloid P-Component; D006820:Hyaluronic Acid