Association between azathioprine therapy and lymphoma in rheumatoid disease.
Three out of 41 patients treated with azathioprine and low-dose corticosteroids from 1976 to 1983 developed non-Hodgkin's lymphoma. This strikingly high incidence of lymphoma may be a reflection of long-term use of azathioprine.
Pitt
P I
PI
Department of Rheumatology, King's College Hospital, London.
Sultan
A H
AH
Malone
M
M
Andrews
V
V
Hamilton
E B
EB
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D001379:Azathioprine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D001379:Azathioprine