title: Effects of sugar and aspartame on aggression and activity in children.
abstract: Habitual sugar consumption and behavior following challenge by sugar and aspartame were studied in 30 preschool boys. The 18 subjects whose parents considered them sugar reactive had more disruptive behavior problems at baseline than the other 12 subjects. Habitual sugar consumption correlated only with duration of aggression against property in alleged responders. Double-blind crossover challenges with aspartame, saccharin, sucrose, and glucose produced no significant effect on aggression or observers' ratings of behavior. Lower actometer counts followed the trials of aspartame, but the difference was not apparent to observers. It is unlikely that sugar and aspartame are clinically significant causes of disruptive behavior.
authors: Child Psychiatry Branch, NIMH, Bethesda, MD 20892.
authors: M J
authors: MJ
authors: Kruesi
authors: J L
authors: JL
authors: Rapoport
authors: E M
authors: EM
authors: Cummings
authors: C J
authors: CJ
authors: Berg
authors: D R
authors: DR
authors: Ismond
authors: M
authors: M
authors: Flament
authors: M
authors: M
authors: Yarrow
authors: C
authors: C
authors: Zahn-Waxler
mesh_terms: D000374:Aggression / Q000187:drug effects*; D001218:Aspartame / Q000009:adverse effects / Q000494:pharmacology*; D002652:Child Behavior / Q000187:drug effects*; D002653:Child Behavior Disorders / Q000139:chemically induced*; D002675:Child, Preschool; D004040:Dietary Carbohydrates / Q000009:adverse effects / Q000494:pharmacology*; D004151:Dipeptides / Q000494:pharmacology*; D005947:Glucose / Q000009:adverse effects / Q000494:pharmacology; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D012439:Saccharin / Q000009:adverse effects / Q000494:pharmacology; D013395:Sucrose / Q000009:adverse effects / Q000494:pharmacology
chemical_list: D004040:Dietary Carbohydrates; D004151:Dipeptides; D013395:Sucrose; D012439:Saccharin; D005947:Glucose; D001218:Aspartame