Tissue response of several polymeric materials implanted in the rat middle ear.
Implantation of three different polymeric composite materials in the rat middle ear showed that the nylon prosthesis was encapsulated more rapidly than the two poly(methyl methacrylate) based implants. Several PMMA based implants were only partially covered at the 6 mnth stage by a tenuous capsule made up of collagen and a mixed inflammatory cell infiltrate. The nylon material was covered at the 3 mnth stage with a thin capsule and healthy fibroblasts.
Williams
K R
KR
Department of Restorative Dentistry, Dental School, University of Wales College of Medicine, Heath Park, Cardiff, UK.
Blayney
A W
AW
D000180:Acrylic Resins / Q000009:adverse effects; D000818:Animals; D001672:Biocompatible Materials; D004432:Ear, Middle / Q000473:pathology / Q000601:surgery*; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D009757:Nylons / Q000009:adverse effects; D011108:Polymers / Q000009:adverse effects; D019736:Prostheses and Implants / Q000009:adverse effects*; D051381:Rats
D000180:Acrylic Resins; D001672:Biocompatible Materials; C039578:Kevlar Aramid fibers; D009757:Nylons; D011108:Polymers; C036222:nylon 12; C040291:Lucitone