title: The effects of intraoperative blood salvage and induced hypotension on transfusion requirements during spinal surgical procedures.
abstract: Spinal surgical procedures, such as placement of Harrington rods for correction of scoliosis, are associated with considerable perioperative blood loss and, hence, with the risks associated with homologous blood transfusions. To test the hypothesis that intraoperative autologous blood transfusions could decrease the amount of homologous blood needed in such operations, we conducted a two-part study: (1) a retrospective review of 142 patients in whom blood salvage was not used and (2) a prospective review of 28 patients who received autologous transfusions. Intraoperative autologous transfusion reduced the amount of homologous blood required by more than 50% (5.1 versus 2.0 units; P less than 0.001). The total amount of homologous blood required during the hospital stay was also significantly reduced by intraoperative autologous transfusion (6.0 versus 3.4 units; P less than 0.001). Induced hypotension in 81 of the 142 patients who did not receive autologous transfusions did not decrease the homologous blood transfusion requirements from those needed by the normotensive patients. We conclude that intraoperative autologous transfusion significantly reduces the need for homologous blood products in patients who undergo spinal surgical procedures. Induced hypotension, which did not affect transfusion requirements in our study, should be further evaluated in a blinded, prospective study.
authors: Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905.
authors: R L
authors: RL
authors: Lennon
authors: M P
authors: MP
authors: Hosking
authors: J R
authors: JR
authors: Gray
authors: R A
authors: RA
authors: Klassen
authors: M A
authors: MA
authors: Popovsky
authors: M A
authors: MA
authors: Warner
mesh_terms: D000328:Adult; D001803:Blood Transfusion; D001804:Blood Transfusion, Autologous; D006801:Humans; D007023:Hypotension, Controlled; D007432:Intraoperative Period; D011446:Prospective Studies; D012189:Retrospective Studies; D012600:Scoliosis / Q000601:surgery; D013131:Spine / Q000601:surgery*