Long-term survival in patients with Ewing's sarcoma relapsing after completing therapy.
While the proportion of patients with Ewing's sarcoma attaining and maintaining long-term remission has markedly improved, a proportion of patients suffer relapse of the tumor. In our experience relapses may occur late in the course of the disease, approximately 20% of those at risk beyond 5 years having recurrence of tumor. Review of our data indicates that for patients relapsing after therapy has been discontinued, the probability of attaining second remission is high (0.84) and that a significant proportion of these patients attaining second complete remission will survive their disease (0.60).
Hayes
F A
FA
Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, TN 38101.
Thompson
E I
EI
Kumar
M
M
Hustu
H O
HO
D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D011379:Prognosis; D012074:Remission Induction; D012512:Sarcoma, Ewing / Q000473:pathology / Q000628:therapy*