[Ring chromosome 4 in twins].
A case of ring chromosome 4 in an eleven months old male child with severe mental retardation, microcephaly and craniofacial anomalies is described. The karyotype was: 46,XY, r(4) p16----q35). The patient shows only few elements of the Wolf syndrome, whose phenotype is observed in most of the other cases with analogue karyotype.
Giuffrè
L
L
Clinica Pediatrica B, Università di Palermo, Italia.
Cammarata
M
M
Corsello
G
G
Benigno
V
V
Graziano
L
L
Roccella
F
F
Balsamo
V
V
D000015:Abnormalities, Multiple / Q000235:genetics*; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002894:Chromosomes, Human, Pair 4; D004200:Diseases in Twins; D006801:Humans; D007223:Infant; D008297:Male; D012303:Ring Chromosomes
Cromosoma 4 ad anello in gemello.