title: [Computer programs for the analysis of nucleotide sequences (MALK)].
abstract: A system for the computer analysis of nucleic acid and protein sequences ("Helix") is described. Format of the DNA sequences is EMBL--compatible and may be easily commented with the help of convenient menus. "Helix" has also following possibilities: an effective alignment of gele reading data and formation of the final sequence; simple making of recombined molecules "in calcular"; calculations of nucleotide and dinucleotide distribution along the sequence; looking for coding frames; calculations percentage of codons and amino acids in coding frames; searching for direct and inverted repeats; sequences alignment; protein secondary structure prediction; restriction mapping; DNA--protein translation. "Helix" also contain programs for RNA-structure prediction, looking for homologies throughover the EMAL bank, choosing optimal sequence for probes and searching promoters. All the programs are written at FORTRAN-77 and automatically translated into FORTRAN-4. "Helix" require only 64 kbite.
authors: A A
authors: AA
authors: Mironov
authors: N N
authors: NN
authors: Aleksandrov
authors: L V
authors: LV
authors: Liunovskaia-Gurova
authors: A E
authors: AE
authors: Kister
mesh_terms: D001483:Base Sequence; D003201:Computers; D008838:Microcomputers; D012984:Software
vernacular_title: Paket prikladnykh programm dlia analiza nukleotidnykh posledovatel'nosteĭ (MALK).