Release kinetics of potassium aspartate in polyvinyl chloride matrix formulation.
The authors prepared potassium aspartate matrix tablets in combination with polyvinyl chloride. The physical parameters were measured and the dissolution rates were determined. During the in vitro release rate experiments, it was determined that the dissolution kinetics obey both zero order and Higuchi diffusion model order kinetics.
Gaizer
S N
SN
Department of Pharmaceutical Technology, Szeged, University of Medical Sciences, Hungary.
Pintye-Hódi
K
K
Selmeczi
B
B
D001224:Aspartic Acid / Q000008:administration & dosage / Q000032:analysis*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004058:Diffusion; D010316:Particle Size; D011143:Polyvinyl Chloride; D012995:Solubility; D013608:Tablets, Enteric-Coated
D013608:Tablets, Enteric-Coated; D001224:Aspartic Acid; D011143:Polyvinyl Chloride