[Effect of the radioprotector adeturon on radiation injury in mice with Lewis carcinoma of the lung].
A study was made of the radioprotective effect of Adeturon, a protective agent obtained in Bulgaria, on mice with Luis lung tumors exposed to fractionated radiation. The effect of the radioprotector on a radiation-induced injury to normal tissue was estimated by the number of leucocytes in the peripheral blood and its count, cellularity of bone marrow and spleen and the mass of the latter, and by the number of exogenous and endogenous CFUs. A pronounced radioprotective effect of Adeturon was implemented through maintaining or normalizing the indices under study impaired by tumor inoculation or irradiation.
Pantev
T P
TP
Mircheva
I I
II
D000255:Adenosine Triphosphate / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000818:Animals; D003114:Colony-Forming Units Assay; D005260:Female; D006412:Hematopoietic Stem Cells / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects; D007958:Leukocyte Count / Q000187:drug effects / Q000528:radiation effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000532:radiotherapy*; D011833:Radiation Injuries, Experimental / Q000209:etiology / Q000401:mortality / Q000473:pathology / Q000517:prevention & control*; D011836:Radiation Tolerance; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D000338:beta-Aminoethyl Isothiourea / Q000031:analogs & derivatives* / Q000627:therapeutic use
D011837:Radiation-Protective Agents; D000338:beta-Aminoethyl Isothiourea; C012704:Adeturon; D000255:Adenosine Triphosphate
Vliianie radioprotektora adeturona na radiatsionnoe porazhenie mysheĭ s kartsinomoĭ legkikh L'iuisa.