The effect of nifedipine on cystoscopy-induced autonomic hyperreflexia in patients with high spinal cord injuries.
We evaluated the ability of the calcium channel blocker nifedipine to control autonomic hyperreflexia during cystoscopy in 7 patients with cervical spinal cord injuries. Nifedipine (10 mg.) alleviated autonomic hyperreflexia when given sublingually during cystoscopy and prevented autonomic hyperreflexia when given orally 30 minutes before cystoscopy. No adverse drug effects were observed.
Dykstra
D D
DD
Department of Physical Medicine, University of Minnesota Health Sciences Center, Minneapolis.
Sidi
A A
AA
Anderson
L C
LC
D000284:Administration, Oral; D000286:Administration, Sublingual; D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000209:etiology / Q000517:prevention & control*; D003558:Cystoscopy / Q000009:adverse effects* / Q000379:methods; D004341:Drug Evaluation; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage*; D012021:Reflex, Abnormal / Q000209:etiology / Q000517:prevention & control*; D013119:Spinal Cord Injuries / Q000150:complications* / Q000503:physiopathology
D009543:Nifedipine