Adjunctive hysterectomy following radiation therapy for bulky carcinoma of the uterine cervix: prognostic implications of tumor persistence.
Twenty-five patients underwent adjunctive extrafascial hysterectomy 14-60 days following completion of external and intracavitary irradiation for bulky carcinoma of the uterine cervix. Review of the operative histopathology and correlation with subsequent patient outcomes suggests that morphologically persistent cancer is prognostically ominous and that cancer near the surgical margin is viable in the majority of instances.
Russell
A H
AH
Department of Radiation Oncology, University of Washington School of Medicine, Seattle 98195.
Burt
A R
AR
Ek
M
M
Russell
K J
KJ
Cain
J M
JM
Greer
B E
BE
Tamimi
H K
HK
Figge
D C
DC
D000230:Adenocarcinoma / Q000532:radiotherapy* / Q000601:surgery; D002277:Carcinoma / Q000532:radiotherapy* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local; D011300:Preoperative Care; D011379:Prognosis; D014594:Uterine Neoplasms / Q000532:radiotherapy* / Q000601:surgery