[Hypothalamic mechanisms regulating the activity of the respiratory neurons of the medulla oblongata in hypoxia].
Under normal conditions of atmosphere pressure the electrical stimulation of hypothalamus induced activating influence on the medullary respiratory and reticular neurons. At the initial stage of the hypoxia (the altitude 4500-5000 m), against the background of hypoxic activation of firing rate, facilitating influence of tetanic stimulation of hypothalamus was lesser though it prevailed over its inhibiting action. At the maximal altitude (8000-9000 m), against the background of hypoxic depression of unit activity, the stimulation of hypothalamus exerted mainly a stimulating effect. That response was particularly obvious in the neurons with low spontaneous activity.
Karapetian
M A
MA
Akopian
N S
NS
Baklavadzhian
O G
OG
D000208:Acute Disease; D000531:Altitude; D000818:Animals; D004558:Electric Stimulation; D005071:Evoked Potentials; D007031:Hypothalamus / Q000503:physiopathology*; D000860:Hypoxia / Q000503:physiopathology*; D008526:Medulla Oblongata / Q000503:physiopathology*; D008839:Microelectrodes; D009474:Neurons / Q000502:physiology*; D051381:Rats; D012119:Respiration; D012125:Respiratory Center / Q000503:physiopathology
Issledovanie gipotalamicheskikh mekhanizmov reguliatsii aktivnosti dykhatel'nykh neĭronov prodolgovatogo mozga v usloviiakh gipoksii.