Presence of macrophages at the bone-cement interface of stable hip arthroplasty components.
The bone cement interface of four clinically stable hip-joint prosthetic components was examined histologically for the presence of macrophages using routine staining and a histochemical technique for acid phosphatase. Macrophages were found in the absence of wear debris in all four cases. Because these cells are capable of bone resorption, their presence at a well-fixed interface must give cause for concern.
Levack
B
B
Department of Orthopedics, London Hospital, Whitechapel, U.K.
Revell
P A
PA
Freeman
M A
MA
D000135:Acid Phosphatase / Q000032:analysis; D000368:Aged; D001843:Bone Cements; D001842:Bone and Bones / Q000166:cytology* / Q000201:enzymology; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D007150:Immunohistochemistry; D008264:Macrophages / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure
D001843:Bone Cements; D000135:Acid Phosphatase