title: Cerebral and brain stem changes after ECT revealed by nuclear magnetic resonance imaging.
abstract: Nuclear magnetic resonance images of the brain were obtained in fourteen patients with major depression during a course of ECT. The T1 relaxation time rose immediately after the fit, reaching a maximum 4-6 h later. The T1 values then returned to their original level; no long-term increase occurred over the course of treatment. These results are consistent with an extensive but temporary breakdown of the blood-brain barrier during ECT.
authors: Royal Edinburgh Hospital, Morningside.
authors: A J
authors: AJ
authors: Mander
authors: A
authors: A
authors: Whitfield
authors: D M
authors: DM
authors: Kean
authors: M A
authors: MA
authors: Smith
authors: R H
authors: RH
authors: Douglas
authors: R E
authors: RE
authors: Kendell
mesh_terms: D001921:Brain / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology; D003866:Depressive Disorder / Q000473:pathology / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D013997:Time Factors