Effect of decontamination procedures on recovery of Nocardia spp.
Exposure to 0.5% N-acetyl-L-cysteine (NAC), 2% NaOH-NAC, or benzalkonium chloride in trisodium phosphate (Zephiran-TSP) was toxic for Nocardia isolates. The number of viable Nocardia cells in a standardized suspension was reduced by 10(2) to 10(6) after a 30-min exposure to 2% NaOH-NAC and by 10(4) or more after a 30-min treatment with Zephiran-TSP.
Murray
P R
PR
Clinical Microbiology Laboratory, Barnes Hospital, Saint Louis, Missouri 63110.
Heeren
R L
RL
Niles
A C
AC
D000111:Acetylcysteine / Q000494:pharmacology*; D001548:Benzalkonium Compounds / Q000494:pharmacology*; D006801:Humans; D009615:Nocardia / Q000187:drug effects* / Q000254:growth & development; D012972:Sodium Hydroxide / Q000494:pharmacology*
D001548:Benzalkonium Compounds; D012972:Sodium Hydroxide; D000111:Acetylcysteine