Predominance of capsular polysaccharide type 5 among oxacillin-resistant Staphylococcus aureus.
The relationship between capsular polysaccharide types 5 and 8 and resistance of Staphylococcus aureus to oxacillin was studied with a collection of 406 clinical isolates from six French hospitals. Of 175 type 5 isolates, 84 (48%) were resistant to oxacillin. In contrast, only 8 of 160 type 8 isolates (5%) and 5 of 71 nontypeable isolates (7%) were resistant to oxacillin. Therefore, capsular typing of clinical isolates of S. aureus may facilitate the choice of first-line antibiotic therapy.
Fournier
J M
JM
Institut Pasteur, Paris, France.
Bouvet
A
A
Boutonnier
A
A
Audurier
A
A
Goldstein
F
F
Pierre
J
J
Bure
A
A
Lebrun
L
L
Hochkeppel
H K
HK
D016667:Bacterial Capsules; D006801:Humans; D010068:Oxacillin / Q000494:pharmacology*; D010403:Penicillin Resistance; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D013211:Staphylococcus aureus / Q000032:analysis / Q000187:drug effects*
D011135:Polysaccharides, Bacterial; C054106:capsular polysaccharide, type 5, Staphylococcus aureus; D010068:Oxacillin