The human alpha 2(IV) collagen gene, COL4A2, is syntenic with the alpha 1(IV) gene, COL4A1, on chromosome 13.
We have previously assigned the gene for the alpha 1 chain of type IV collagen to chromosome 13. In this report we show that the gene coding for the second chain of this heterotrimer is on the same chromosome. This is the first example of the genes for both chains of one collagen molecule being syntenic.
Solomon
E
E
Imperial Cancer Research Fund, Lincoln's Inn Fields, London.
Hall
V
V
Kurkinen
M
M
D000818:Animals; D002882:Chromosomes, Human, Pair 13; D003094:Collagen / Q000235:genetics*; D004247:DNA; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D009693:Nucleic Acid Hybridization
D003094:Collagen; D004247:DNA