title: Perforated peptic ulcer--a complication in acute salicylate intoxication.
abstract: A patient with perforated peptic ulcer following acute salicylate intoxication is presented. The patient had reversible renal failure requiring dialysis therapy, but no abdominal symptoms were noticed until six days after arrival. At this time haematemesis and melaena were observed. Symptoms and objective findings were vague, but further investigations revealed a perforated prepyloric ulcer, which was successfully treated with cimetidine, The delay from intoxication to symptoms has previously been described and might be due to the analgetic properties of salicylates.
authors: Department of Internal Medicine and Nephrology, Aalborg Hospital, Denmark.
authors: L A
authors: LA
authors: Christensen
authors: E B
authors: EB
authors: Schmidt
mesh_terms: D000208:Acute Disease; D058186:Acute Kidney Injury / Q000139:chemically induced / Q000628:therapy; D001241:Aspirin / Q000506:poisoning*; D002927:Cimetidine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000139:chemically induced* / Q000188:drug therapy; D006435:Renal Dialysis
chemical_list: D002927:Cimetidine; D001241:Aspirin