title: [Preparations of acetylsalicylic acid sustained-release tablets on hydrophilic matrix forms].
abstract: The aim of this study was to prepare a tablet with acetylsalicylic acid based on hydrophilic matrix form by means of polyvinyl alcohol. The liberation was carried out with the column dissolution-rate method. In contrast to other studies, the percentage of the cumulative liberation is decreased by increasing the drug concentration. Acetylsalicylic acid caused a decrease of the wetting and the rate of swelling.
authors: Pharmazeutisches Zentrum Oschatz, Klinikapotheke Hubertusburg, Wermsdorf.
authors: W
authors: W
authors: Süss
authors: K
authors: K
authors: Bruder
mesh_terms: D001241:Aspirin / Q000008:administration & dosage*; D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D005079:Excipients; D011142:Polyvinyl Alcohol
chemical_list: D003692:Delayed-Action Preparations; D005079:Excipients; D011142:Polyvinyl Alcohol; D001241:Aspirin
vernacular_title: Herstellung von Acetylsalicylsäuretabletten mit verzögerter Wirkstoffliberation auf der Basis hydrophiler Matrixformen.