title: Isolation and characterization of novel glycolipids with blood group A-related structures: galactosyl-A and sialosylgalactosyl-A.
abstract: Two glycosphingolipids with the following novel structures have been isolated from human blood cells and characterized by NMR, direct probe mass spectrometry, fast atom bombardment-mass spectrometry, and methylation analysis: (Formula: see text). Both structure i and structure ii are characterized by substitution of beta-galactosyl or sialosyl-beta-galactosyl residue at the terminal alpha-GalNAc residue of blood group A determinant and are therefore specific products associated with the blood group A phenotype.
authors: Department of Pathobiology, University of Washington, Seattle 98119.
authors: H
authors: H
authors: Clausen
authors: S B
authors: SB
authors: Levery
authors: E D
authors: ED
authors: Nudelman
authors: M
authors: M
authors: Stroud
authors: M E
authors: ME
authors: Salyan
authors: S
authors: S
authors: Hakomori
mesh_terms: D000017:ABO Blood-Group System; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D006017:Glycolipids / Q000097:blood* / Q000302:isolation & purification; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008745:Methylation; D008969:Molecular Sequence Data
chemical_list: D000017:ABO Blood-Group System; D006017:Glycolipids