title: [Effect of rat liver gangliosides on the interaction of liposomes with rat hepatocytes in vitro].
abstract: The influence of rat liver GM1, GM2, GD1 and GT1 gangliosides on the interaction of liposomes with rat hepatocytes was investigated. It was shown that liposomes coated with GM1 and GT1 are effectively bound and captured by hepatocytes. Preincubation of hepatocytes with N-acetylglucosamine and D-galactose reduced the binding of GM1- and GT1-liposomes by those cells. The data obtained suggest that there are binding sites for some gangliosides on the surface of rat hepatocytes.
authors: S A
authors: SA
authors: Burkhanov
authors: V A
authors: VA
authors: Kosykh
authors: V S
authors: VS
authors: Repin
authors: V P
authors: VP
authors: Torchilin
mesh_terms: D000818:Animals; D001665:Binding Sites; D005732:Gangliosides / Q000378:metabolism*; D066298:In Vitro Techniques; D008081:Liposomes / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats
chemical_list: D005732:Gangliosides; D008081:Liposomes
vernacular_title: Vliianie gangliozidov pecheni krys na vzaimodeĭstvie liposom s gepatotsitami krys in vitro.