The interaction of nicotinic receptor antagonists at muscarinic receptors.
1. The interaction of some neuromuscular blocking drugs such as gallamine, pancuronium and stercuronium with muscarinic receptors has several features which distinguish these compounds from competitive antagonists in functional and binding studies. 2. They also differentiate between muscarinic receptors and may produce effects on ion channels.
Mitchelson
F J
FJ
School of Pharmacology, Victorian College of Pharmacy, Melbourne, Australia.
D000470:Alkaloids / Q000494:pharmacology; D000818:Animals; D005703:Gallamine Triethiodide / Q000494:pharmacology; D005731:Ganglionic Stimulants / Q000494:pharmacology; D006168:Guinea Pigs; D006325:Heart Atria / Q000187:drug effects; D066298:In Vitro Techniques; D009467:Neuromuscular Depolarizing Agents / Q000494:pharmacology*; D010197:Pancuronium / Q000494:pharmacology; D011976:Receptors, Muscarinic / Q000187:drug effects / Q000502:physiology
D000470:Alkaloids; D005731:Ganglionic Stimulants; D009467:Neuromuscular Depolarizing Agents; D011976:Receptors, Muscarinic; D010197:Pancuronium; D005703:Gallamine Triethiodide; C003344:stercuronium