Comparative trial of cefuroxime axetil in recurrent urinary tract infections illustrating importance of 6-week follow-up.
Women with recurrent urinary tract infections treated with cefuroxime axetil (500 or 250 mg twice daily) for 7 days had a higher relapse rate when tested 6 weeks after the start of treatment than those given amoxycillin (250 mg three times daily). The poor performance of cefuroxime axetil is explained by variable bioavailability.
Brumfitt
W
W
Department of Medical Microbiology, Royal Free Hospital, School of Medicine, Hampstead, London, England.
Hamilton-Miller
J M
JM
Smith
G W
GW
D000658:Amoxicillin / Q000627:therapeutic use; D001682:Biological Availability; D002444:Cefuroxime / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002511:Cephalosporins; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D014552:Urinary Tract Infections / Q000188:drug therapy*
D002511:Cephalosporins; D000658:Amoxicillin; D002444:Cefuroxime; C040738:cefuroxime axetil