[Pharmacokinetic characteristics of ethacizine in patients with disorders of heart rhythm].
Significant differences in values of the volume of ethacizine distribution and clearance at oral administration in patients with myocardial infarction from those in patients with other pathology were established. A considerable decrease of ethacizine bioavailability in myocardial infarction patients was shown.
Gneushev
E T
ET
Kurapov
A P
AP
Beliakova
G A
GA
Zagrebin
S V
SV
Starodubtsev
A K
AK
D000284:Administration, Oral; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000378:metabolism*; D001682:Biological Availability; D006801:Humans; D007275:Injections, Intravenous; D008433:Mathematics; D009203:Myocardial Infarction / Q000188:drug therapy / Q000378:metabolism; D010640:Phenothiazines / Q000008:administration & dosage / Q000493:pharmacokinetics*; D013997:Time Factors
D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines; C046818:ethacizine
Osobennosti farmakokinetiki étatsizina u bol'nykh s narusheniiami ritma serdechnoĭ deiatel'nosti.