Disseminated meningeal tumor in a dog.
A 6-year-old Golden Retriever was referred for evaluation of hind limb paresis and generalized weakness. Neurologic examination revealed multifocal cervical and lumbosacral spinal disease. Radiography and myelography failed to identify a lesion. Cerebrospinal fluid was markedly cellular and had a high protein concentration, consistent with myelitis or a neoplastic process. The dog did not improve with medical management. Gross and histologic examination of the brain and spinal cord revealed a thick meningeal surface characterized by polymorphic histiocytic-like cells to multinucleate giant cells. The neoplastic process was considered to be a disseminated meningeal polymorphic cell sarcoma.
Hay
W H
WH
Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61801.
Ogilvie
G K
GK
Parker
A J
AJ
Daniel
G B
GB
Dorner
J L
JL
Simon
J
J
D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000662:veterinary*; D012509:Sarcoma / Q000473:pathology / Q000662:veterinary*