Prevention of neuroma formation by Neodym Yag laser--experimental observations.
The influence of Laser radiation on neuroma formation was investigated in rat sciatic nerves. Peripheral nerve trunks were divided by focused Neodym Yag Laser and compared with those transected by microscissors. The nerves were re-exposed at different time intervals up to 240 days after initial operation. True neuroma formation could not be observed after laser transection. Sharp division resulted in widespread amputation neuromas consisting of regenerating axons and connective tissue. Neodym Yag laser radiation by its scattering effect may cause deep coagulation necrosis and thrombosis of vasa nervorum thus sealing the dome of the divided nerve trunk. The formation of amputation neuromas may be suppressed by laser application.
König
H J
HJ
Westfälische Wilhelms-Universität Münster, Federal Republic of Germany.
Themann
H
H
Hiller
U
U
Gullotta
F
F
D000672:Amputation Stumps; D000818:Animals; D003714:Denervation; D053685:Laser Therapy; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009463:Neuroma / Q000517:prevention & control*; D051381:Rats; D012584:Sciatic Nerve / Q000648:ultrastructure