Contact allergy to hydrocortisone and thixocortol pivalate: problems in the detection of corticosteroid sensitivity.
Several of the difficulties involved in the detection of corticosteroid allergy are illustrated by the problems encountered in a patient sensitive to a preparation containing hydrocortisone and miconazole nitrate. The importance of appropriate concentrations and vehicles for patch testing, the possible rôle of impurities, and cross-sensitivity of corticosteroid molecules are discussed.
A
A
Dooms-Goossens
H
H
Verschaeve
H
H
Degreef
J
J
van Berendoncks
D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D003877:Dermatitis, Contact / Q000209:etiology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects* / Q000031:analogs & derivatives*; D008825:Miconazole / Q000009:adverse effects; D010328:Patch Tests
D000893:Anti-Inflammatory Agents; C019112:tixocortol pivalate; D008825:Miconazole; D006854:Hydrocortisone