Changes of dipole moments in the series of Boc-(ProLeuGly)n-OBzl oligopeptides and their possible explanation. A preliminary survey.
It was found that the dipole moments in the series of Boc-(ProLeuGly)n-OBzl oligopeptides (n = 1-5) measured in dioxane solution demonstrate a distinct concentration dependence beginning from dodecapeptide. This effect may be connected with the appearance of aggregated (triple-helical?) structure in conformation equilibrium. The tendency to minimize the dipole moment of the system may be of some importance in the creation of supercoiled structures of polypeptides.
Siemion
I Z
IZ
Institute of Chemistry, Wroclaw University, Poland.
Pedyczak
A
A
Rospenk
M
M
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002942:Circular Dichroism; D009842:Oligopeptides; D011487:Protein Conformation
D009842:Oligopeptides