[Carcinogenesis-modifying properties of aniline, carbon tetrachloride, benzene and ethanol].
Aniline and ethanol properties modifying carcinogenesis were revealed in chronic 12-month experiment with 500 females of hybrid CBAXC57Bl/6 mice. The drugs were administered with water in combination with nitrosodiethylamine. The absence of a modifying effect in groups with carbon tetrachloride and benzene is attributed to the fact that concentrations of these chemicals used in the experiment were similar to those in the environment.
N N
NN
Litvinov
V M
VM
Voronin
V I
VI
Kazachkov
D000814:Aniline Compounds / Q000633:toxicity*; D000818:Animals; D001554:Benzene / Q000633:toxicity*; D002251:Carbon Tetrachloride / Q000633:toxicity*; D004128:Dimethylnitrosamine; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000453:epidemiology; D013997:Time Factors
D000814:Aniline Compounds; D000431:Ethanol; D002251:Carbon Tetrachloride; D001554:Benzene; D004128:Dimethylnitrosamine; C023650:aniline
Izuchenie modifitsiruiuschikh kantserogenez svoĭstv anilina, chetyrekhkhloristogo ugleroda, benzola i étanola.