[Spontaneous corneal rupture after strontium irradiation of a conjunctival squamous cell carcinoma].
A 87-year-old female patient with a squamous cell carcinoma of the conjunctiva was treated with local strontium-90 irradiation (with a so-called 'Dermaplatte'). In spite of a relatively low dosage, radiotherapy was followed by a corneal ulcer with consecutive rupture of the cornea. The cause of this unexpected perforation was, besides the effect of low-dose irradiation, probably a metabolic disorder of the cornea and a disturbance of the tear film due to the carcinoma which had spread on Bowman's layer of the cornea in an exophytic manner and was accompanied by a dense lymphocytic infiltration. An exenteration was performed and, at the last examination (1 year later), no local recurrence could be detected.
Philipp
W
W
Universitäts-Klinik für Augenheilkunde, Innsbruck.
Daxecker
F
F
Langmayr
J
J
Göttinger
W
W
D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D003230:Conjunctival Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D003315:Cornea / Q000473:pathology; D003320:Corneal Ulcer / Q000209:etiology*; D005260:Female; D006801:Humans; D012422:Rupture, Spontaneous; D013326:Strontium Radioisotopes / Q000009:adverse effects*
D013326:Strontium Radioisotopes
Spontane Hornhautruptur nach Strontiumbestrahlung eines Plattenepithelkarzinoms der Konjunktiva.