Hodgkin's disease presenting with superficial lymph nodes and tumors of the scalp.
Invasion of the skin by malignant cells in Hodgkin's disease is a rare occurrence and less common than skin involvement in non-Hodgkin's lymphoma. We describe a 36-year-old man with Hodgkin's disease who presented with superficial lymph nodes and tumors on the scalp as initial clinical findings. Biopsy of a tumor of the scalp showed a diffuse dermal infiltrate composed of polynuclear neutrophils and eosinophils, large lymphocytes, and Sternberg-Reed cells. Ultrastructural examination of the skin biopsy specimens demonstrated the characteristic morphology of the Sternberg-Reed cells.
Torne
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Umbert
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D000328:Adult; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D012535:Scalp / Q000473:pathology* / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000648:ultrastructure