Pathology of renal secondary hyperparathyroidism in mice.
Typical renal secondary hyperparathyroidism was observed in 19 specific pathogen-free ICR mice. The renal lesions were severe amyloidosis and glomerulonephritis. The bone lesion, osteodystrophia fibrosa, consisted of both resorptive and reparative processes. The parathyroid glands were enlarged and there was hyperplasia of the chief cells.
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Yamasaki
D000686:Amyloidosis / Q000473:pathology; D000818:Animals; D001842:Bone and Bones / Q000473:pathology; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000473:pathology / Q000662:veterinary*; D005260:Female; D005921:Glomerulonephritis / Q000473:pathology; D007668:Kidney / Q000473:pathology; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D010280:Parathyroid Glands / Q000473:pathology; D012376:Rodent Diseases / Q000473:pathology*