Small effect on plasma selenium level by occupational lead exposure.
Selenium level in plasma (P-Se) was slightly, but statistically significantly (2p = 0.02) lower in 25 lead-exposed secondary smelter workers (P-Se 1.09 +/- 0.02 mumol l-1, mean +/- SEM; blood lead level, B-Pb, 1.9 +/- 0.1 mumol l-1) than in 25 matched controls (P-Se 1.16 +/- 0.03 mumol l-1; B-Pb 0.2 +/- 0.01 mumol l-1). Further, there was a significant negative (2p = 0.02) correlation (r = -0.33) between B-Pb and P-Se. The data indicate a minor interaction, in humans, between occupational lead exposure and selenium status.
Department of Occupational Medicine, University Hospital, Lund, Sweden.
A
A
Gustafson
A
A
Schütz
P
P
Andersson
S
S
Skerfving
D000328:Adult; D004347:Drug Interactions; D004781:Environmental Exposure; D006801:Humans; D007854:Lead / Q000097:blood* / Q000493:pharmacokinetics; D008111:Liver Function Tests; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D009790:Occupations; D012643:Selenium / Q000097:blood* / Q000493:pharmacokinetics
D007854:Lead; D012643:Selenium