Vitamin A promotes DNA synthesis and mitosis in blastemas of Triturus alpestris.
Vitamin A palmitate orally administered to young, post-metamorphic Triturus alpestris (Amphibia-Urodela), for 4 and 7 days after bilateral forelimb amputation at the middle of the zeugopodium, enhanced the mean DNA content of the blastema cells. Moreover, the number of cells in mitosis was nearly twice as high in vitamin A treated animals than in control ones.
University of Athens, Zoological Laboratory, Greece.
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Koussoulakos
H J
HJ
Anton
D000818:Animals; D004247:DNA / Q000096:biosynthesis*; D004224:Diterpenes; D008938:Mitosis / Q000187:drug effects*; D012038:Regeneration / Q000187:drug effects; D000084562:Retinyl Esters; D014319:Triturus / Q000033:anatomy & histology / Q000502:physiology*; D014801:Vitamin A / Q000031:analogs & derivatives* / Q000494:pharmacology
D004224:Diterpenes; D000084562:Retinyl Esters; D014801:Vitamin A; C014794:retinol palmitate; D004247:DNA