Hemodynamic effects of experimental testicular torsion.
Experimental testicular torsion must be used for certain studies of clinical relevance, but most experimental models either do not provide hemodynamic alteration comparable to the clinical situation or cannot guarantee reproducibility. Using a rat model arterial perfusion and hemorrhagic infarction were correlated to the degree of both intra- and extravaginal testicular torsion. Arterial inflow was measured sequentially with radiolabelled microspheres, hemorrhagic infarction was judged by the increase of testicular weight. Maximal hemorrhagic infarction and reproducible values were found when the spermatic cord was twisted together with the tunica vaginalis for 360 degrees-540 degrees.
Department of Urology, University of Mainz, Medical School, Federal Republic of Germany.
G
G
Janetschek
F
F
Schreckenberg
W
W
Grimm
M
M
Marberger
D000818:Animals; D001158:Arteries / Q000503:physiopathology; D004195:Disease Models, Animal; D006439:Hemodynamics; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007238:Infarction / Q000209:etiology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013086:Spermatic Cord Torsion / Q000150:complications / Q000503:physiopathology*; D013737:Testis / Q000098:blood supply