[Value of determination of myoglobin concentration in blood in the diagnosis and prognosis of patients with acute myocardial infarction].
Seventy-seven patients with large-focal myocardial infarction (MI), admitted to the intensive-care ward within 5 hours after the attack, were studied. Their serum myoglobin (MG) levels and MB CPK activity were monitored through 3 or 4 days of the disease. All MI patients showed a considerable rise in their serum MG within the first hours of infarction. In addition to its high diagnostic value, the measurement of serum MG can be helpful in assessing the severity and prognosis of the disease. The obtained evidence of a high linear dependence between cumulative MB CPK activity and the area under the MG curve, as well as a high correlation coefficient between the areas under serum MG and MB CPK curves, point in favor of using MG levels as a measure of the extent of the necrotic focus.
Tashmatova
A Iu
AIu
Staroverov
I I
II
Titov
V N
VN
Saprykin
D B
DB
Makarovskiĭ
V V
VV
D000208:Acute Disease; D000368:Aged; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000150:complications / Q000401:mortality; D009211:Myoglobin / Q000097:blood*; D011379:Prognosis; D013997:Time Factors
D007527:Isoenzymes; D009211:Myoglobin; D003402:Creatine Kinase
Znachenie opredeleniia soderzhaniia mioglobina v krovi dlia diagnostiki i prognoza u bol'nykh ostrym infarktom miokarda.