Motor cortical kindling in cats: a comparison of adult cats and kittens.
We compared the establishment of motor cortex kindling by daily electrical stimulation in adult cats and in 4-week-old kittens. All the adult cats and kittens examined reached a stable state of kindled seizures. There was no significant difference in afterdischarge (AD) thresholds, the course of clinical seizure development, or the number of stimuli required for the establishment of kindling between adult cats and kittens. During the development of the kindling stage, AD frequency increased in both adult cats and kittens, although AD duration did not show a clear change.
Department of Physiology, Hokkaido University School of Medicine, Japan.
J
J
Fukushima
S
S
Kohsaka
K
K
Fukushima
M
M
Kato
D000375:Aging / Q000502:physiology*; D000818:Animals; D002415:Cats; D004558:Electric Stimulation / Q000379:methods; D004567:Electrodes, Implanted; D004594:Electrophysiology; D007696:Kindling, Neurologic; D009044:Motor Cortex / Q000502:physiology*; D012640:Seizures / Q000209:etiology / Q000503:physiopathology