Impoverished rearing conditions increase stress-induced irritability in mice.
Irritability was tested in mice reared in four environmental conditions: impoverished (IC), impoverished + overstimulated (ICS), enriched (EC), and enriched + overstimulated (ECS) conditions. The test used was a modified "bottle brush" test. Both overstimulations and individual housing increased irritability interacting positively with each other. Individual housing but not overstimulation decreased avoidance behavior in the mice.
Riittinen
M L
ML
Lindroos
F
F
Kimanen
A
A
Pieninkeroinen
E
E
Pieninkeroinen
I
I
Sippola
J
J
Veilahti
J
J
Bergström
M
M
Johansson
G
G
D000818:Animals; D004644:Emotions; D004777:Environment; D007508:Irritable Mood; D008297:Male; D051379:Mice; D013315:Stress, Psychological / Q000209:etiology*