The possible role of glucose-6-phosphate dehydrogenase in the detoxification of methyl parathion.
The levels of proteins, glucose and glucose-6-phosphate dehydrogenase activity were studied in muscle, gill and liver tissues of the fish Tilapia mossambica under sublethal methyl parathion toxicity. Tissue glucose levels decreased with increased soluble protein content and the activity levels of glucose-6-phosphate dehydrogenase were elevated considerably. These results are discussed in relation to the involvement of glucose-6-phosphate dehydrogenase in both synthetic and detoxification processes as an adaptive response against methyl parathion toxicity.
Zoology Department, S.V. University P.G. Center, Kavali, India.
K S
KS
Rao
K V
KV
Rao
D000818:Animals; D005399:Fishes; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis / Q000502:physiology*; D008658:Inactivation, Metabolic; D008743:Methyl Parathion / Q000378:metabolism* / Q000633:toxicity; D010278:Parathion / Q000031:analogs & derivatives*
D008743:Methyl Parathion; D010278:Parathion; D005954:Glucosephosphate Dehydrogenase