[Relations between lipid metabolism and changes in the vessel wall].
Hyperlipoproteinaemias and dyslipoproteinaemias, respectively, lead to an increased lipid infiltration of the vascular wall. Increased lipid transport takes place vesicularly, by adsorptive endocytosis, contraction of the endothelium and dilation of interendothelial grooves. The increasedly taken lipids are bound to glycosaminoglycanes or elastin. The decomposition of the lipoproteins taken in the vascular wall is decreased. The lipid accumulation stimulates the glycosaminoglycane, elastin and collagen synthesis of the vascular wall.
G
G
Müller
D001161:Arteriosclerosis / Q000473:pathology*; D002114:Calcinosis / Q000473:pathology; D002784:Cholesterol / Q000097:blood; D004727:Endothelium / Q000473:pathology; D006801:Humans; D006951:Hyperlipoproteinemias / Q000473:pathology*; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D009131:Muscle, Smooth, Vascular / Q000473:pathology
D008055:Lipids; D008074:Lipoproteins; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D002784:Cholesterol
Zusammenhänge zwischen Lipidstoffwechsel und Gefässwandveränderungen.