Unusual features of the Guillain-Barré syndrome after rabies vaccine prepared in suckling mouse brain.
Five patients with acute polyneuritis following treatment with rabies vaccine prepared in suckling mouse brains are reported. These patients had severe and protracted disease. The extensive cranial nerve involvement, high mortality rate, and disabling longterm sequelae were in contrast to cases of the Guillain-Barré syndrome not associated with the vaccine.
Department of Neurology, Universidad Peruana Cayetano Heredia, Lima.
J
J
Cabrera
D E
DE
Griffin
R T
RT
Johnson
D000328:Adult; D000818:Animals; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D051379:Mice; D008875:Middle Aged; D010568:Peru; D011129:Polyradiculoneuropathy / Q000276:immunology* / Q000401:mortality / Q000503:physiopathology; D011819:Rabies Vaccines / Q000009:adverse effects*; D014613:Vaccines, Attenuated / Q000276:immunology
D011819:Rabies Vaccines; D014613:Vaccines, Attenuated