Primary chronic abortion, preeclampsia, idiopathic intrauterine growth retardation, hydatidiform mole, and choriocarcinoma: a unifying concept.
Different degrees of maternal hyporesponse, as far as blocking activity is concerned, are proposed for primary chronic abortion, preeclampsia, and idiopathic intrauterine growth retardation. On the other hand, a maternal hyperresponse to fetal antigens with a higher production of blocking antibodies may be related to an unusual proliferation of the trophoblast in cases of hydatidiform mole and choriocarcinoma.
C A
CA
Labarrere
O H
OH
Althabe
D000026:Abortion, Habitual / Q000276:immunology*; D000906:Antibodies / Q000276:immunology; D000941:Antigens / Q000276:immunology; D002822:Choriocarcinoma / Q000276:immunology*; D005260:Female; D005317:Fetal Growth Retardation / Q000276:immunology*; D005333:Fetus / Q000276:immunology; D006801:Humans; D006828:Hydatidiform Mole / Q000276:immunology*; D008431:Maternal-Fetal Exchange; D008954:Models, Biological; D011225:Pre-Eclampsia / Q000276:immunology*; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000276:immunology*
D000906:Antibodies; D000941:Antigens