[Diagnostic value of radionuclide visualization of the reticuloendothelial system of macrophages in multiple sclerosis].
Scintigraphic examination of the liver, spleen, bone marrow and retroperitoneal lymph nodes with the help of colloidal radiopharmaceutical 113mIn was conducted in 55 patients with multiple sclerosis (MS) and in 13 patients with other diseases of the nervous system. The authors ascertained dysfunction of cells of the mononuclear phagocytic system (MPS) in the MS patients. Clinical manifestations of the disease were found to correlate with the findings of radionuclide imaging of the parenchymatous organs and lymph nodes. A conclusion was drawn about the total disruption of the functional activity of MPS cells in MS and the inevitable involvement of the liver in the pathogenesis of the disease.
A P
AP
El'chaninov
A V
AV
Artiushkin
A A
AA
Skoromets
D000293:Adolescent; D000328:Adult; D001853:Bone Marrow / Q000000981:diagnostic imaging; D006801:Humans; D007204:Indium; D007728:Kupffer Cells; D008099:Liver / Q000000981:diagnostic imaging; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008264:Macrophages; D008875:Middle Aged; D012157:Mononuclear Phagocyte System / Q000000981:diagnostic imaging*; D009103:Multiple Sclerosis / Q000000981:diagnostic imaging*; D011868:Radioisotopes; D011877:Radionuclide Imaging; D013154:Spleen / Q000000981:diagnostic imaging
D011868:Radioisotopes; D007204:Indium
Diagnosticheskoe znachenie radionuklidnoĭ vizualizatsii retikuloéndotelial'noĭ sistemy makrofagov u bol'nykh rasseiannym sklerozom.