[Occurrence of antibodies against influenza viruses in the female genital tract of mice following oral immunization].
Antibodies of IgA-class against influenza viruses were detected by an enzyme immunoassay (ELISA) in uterus homogenates and uterus lavage fluids of NMRI-mice following immunization. Immunization was performed twice by the oral route within 14 days using a live influenza vaccine (A/PR/8/34, H1N1). Specific antibodies were estimated in homogenates as well as in lavage fluids. The results support the concept of a common immune mucosal system with local antibody secretion after remote-site stimulation in the intestinal tract.
V
V
Briese
K C
KC
Bergmann
W D
WD
Pohl
K
K
Noack
H
H
Tischner
W
W
Straube
D000284:Administration, Oral; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D005260:Female; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D009980:Influenza A virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D051379:Mice; D014599:Uterus / Q000276:immunology*
D000914:Antibodies, Viral; D007071:Immunoglobulin A, Secretory; D007252:Influenza Vaccines
Auftreten von Antikörpern gegen Influenzaviren im weiblichen Genitaltrakt von Mäusen nach oraler Immunisierung.