[Vaccination against hepatitis B on the Ivory Coast: study of the anti-HBs response in healthy adult subjects carrying only anti-HBc antibodies before vaccination].
A total of 103 volunteers, from 18 to 55 years of age, have received the hevac B Pasteur 5 micrograms vaccine subcutane on sly; one injection a month during three months and one booster injection after one year. The study of the anti-HBs reaction of the subjects, with regard to the serological status to the hepatite B virus before inoculation, has shown that only 78.8% of the subjects, who are only positive towards the anti-HBc antibody, will develop an anti-HBs response of primary type with a relatively low value. In contrast, all anti-HBc and/or anti-HBs subjects, who are positive before inoculation, react with relatively high anti-HBs values right after the first injection, of the seronegative subjects before inoculation. 93.3% will develop an anti-HBs seroconversion after the complete inoculation procedure.
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D000328:Adult; D006509:Hepatitis B / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000032:analysis* / Q000096:biosynthesis; D006512:Hepatitis B Core Antigens / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D008875:Middle Aged; D014761:Viral Hepatitis Vaccines / Q000276:immunology*
D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D014761:Viral Hepatitis Vaccines
Vaccination contre l'hépatite B en Côte-d'Ivoire: étude de la réponse anti-HBs chez des sujets adultes sains porteurs uniquement de l'anticorps anti-HBc avant la vaccination.