A sensitive method to monitor trace quantities of benzanthrone in workers of dyestuff industries.
Dyestuff workers coming in contact with benzanthrone (an intermediate used for the synthesis of a variety of dyes) develop skin lesions, gastritis, liver malfunctions, and sexual disturbances. A highly sensitive fluorometric method to monitor trace quantities of benzanthrone in urine, serum, and biological tissues for experimental studies, has been developed. Coupled with simple extraction and resolution, optimum fluorescence is obtained in an equal mixture of chloroform:methanol, detecting as low as 2 ng benzanthrone. This method is approximately 250 times more sensitive than currently available colorimetric assay.
Joshi
A
A
Khanna
S K
SK
Singh
G B
GB
D001551:Benz(a)Anthracenes / Q000032:analysis* / Q000097:blood / Q000652:urine; D004396:Coloring Agents; D006801:Humans; D007221:Industry; D009784:Occupational Diseases / Q000097:blood / Q000378:metabolism* / Q000652:urine; D012997:Solvents; D013050:Spectrometry, Fluorescence
D001551:Benz(a)Anthracenes; D004396:Coloring Agents; D012997:Solvents; C012768:benzanthrone