Combination of short- and long-term catheter thrombolysis for peripheral arterial occlusion.
To save time and expenses we developed a combined program of local short-term catheter thrombolysis (CTL) in the angiographic laboratory followed by a long-term CTL on the ward if necessary to achieve patency. Out of 66 patients with arterial occlusion in the femoro-popliteal region the occluded segment was re-opened by short-term CTL alone in 22 patients (36%), and in 24 out of the remaining 44 patients by long-term CTL, giving a total primary success rate of 71%. Angiographic analysis showed that primary clinical success depended on the patency of run-off vessels in the calf after CTL. Complications occurred in five patients, necessitating surgical revision in only one. Two years after intervention 64% of the primarily recanalized arteries were still patent as shown by non-invasive examination.
Dept of Medicine (Div. of Angiology), Inselspital, University of Berne.
Do-dai-Do
F
F
Mahler
J
J
Triller
B
B
Nachbur
D000368:Aged; D000369:Aged, 80 and over; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002406:Catheterization, Peripheral / Q000009:adverse effects / Q000379:methods; D002408:Catheters, Indwelling; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging; D005343:Fibrinolytic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000000981:diagnostic imaging; D011859:Radiography; D013997:Time Factors; D014654:Vascular Patency / Q000187:drug effects
D005343:Fibrinolytic Agents