[Amine oxidase activity and blood serotonin levels in cancer of the gastro-intestinal tract and lung].
Activity of amine oxidase less than using serotonin as a substrate greater than and content of serotonin were studied in blood of healthy persons and in patients with carcinoma of stomach, intestine and lung at the III-IV steps of the disease. In the patients with carcinoma of gastrointestinal tract the amine oxidase activity was decreased 2-fold and in the patients with carcinoma of lung it was decreased 4-fold as compared with controls. At the same time, content of serotonin was increased both in blood plasma and in blood platelets of the patients. The increase in content of serotonin depends on localization of the tumors.
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Filatova
D006631:Amine Oxidase (Copper-Containing); D005770:Gastrointestinal Neoplasms / Q000097:blood* / Q000201:enzymology; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood* / Q000201:enzymology; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000097:blood*; D012701:Serotonin / Q000097:blood*
D012701:Serotonin; D006631:Amine Oxidase (Copper-Containing); D000587:Oxidoreductases Acting on CH-NH Group Donors
Aktivnost' aminoksidazy i soderzhanie serotonina v krovi pri rake zheludochno-kishechnogo trakta i legkikh.