The relationship between the acetylator and the sparteine hydroxylation polymorphisms.
Thirty-eight healthy white British Caucasian subjects were hydroxylator phenotyped with sparteine and acetylator phenotyped with sulphadimidine. The results showed that there was no significant difference in the mean sparteine metabolic ratio between eight rapid acetylator extensive hydroxylators and 27 slow acetylator extensive hydroxylators.
Harmer
D
D
Evans
D A
DA
Eze
L C
LC
Jolly
M
M
Whibley
E J
EJ
D000107:Acetylation; D001711:Biotransformation; D006801:Humans; D006900:Hydroxylation; D010641:Phenotype; D011110:Polymorphism, Genetic; D013034:Sparteine / Q000378:metabolism*; D013418:Sulfamethazine / Q000378:metabolism*
D013034:Sparteine; D013418:Sulfamethazine