A new method for granulocyte labeling with technetium-99m: preliminary results in abscess detection.
A new method for 99mTc-labeling of granulocytes for clinical routine use has been developed. The labeling is simple to perform by means of a kit of radiopharmaceutical quality, utilizing dihydroxy-benzoic acid. Pretinning techniques are avoided. The technique has been applied clinically in 15 patients with indications of intra-abdominal abscess. In six patients, [99mTc]granulocyte scintigraphy at 3 hr and/or 24 hr after i.v. administration, correctly depicted the abscess, as verified by subsequent surgery. In the remaining patients, who were negative at surgery or recovered without operation, all scans were negative.
E
E
Sundrehagen
A M
AM
Bengtsson
P O
PO
Bremer
H
H
Jacobsson
S
S
von Krusenstierna
S A
SA
Larsson
P O
PO
Schnell
T
T
Svenberg
P S
PS
Appelgren
D000005:Abdomen; D000038:Abscess / Q000000981:diagnostic imaging*; D001998:Bronchopulmonary Sequestration; D006098:Granulocytes; D006801:Humans; D062385:Hydroxybenzoates; D007553:Isotope Labeling; D011877:Radionuclide Imaging; D013667:Technetium
D062385:Hydroxybenzoates; D013667:Technetium