Isolation of riboflavin carrier proteins from pregnant human and umbilical cord serum: similarities with chicken egg riboflavin carrier protein.
A riboflavin carrier protein has been purified from human pregnancy and umbilical cord sera by affinity chromatography and fast protein liquid chromatography. This protein has a similar molecular weight to the chicken egg riboflavin carrier protein and shares other physicochemical properties, such as pI and riboflavin binding characteristics, with the avian counterpart. A high degree of immunological cross-reactivity is observed between the human and avian riboflavin binding proteins indicating the extensive conservation of this protein throughout evolution.
Visweswariah
S S
SS
Department of Biochemistry, Indian Institute of Science, Bangalore.
Adiga
P R
PR
D000818:Animals; D002352:Carrier Proteins / Q000097:blood* / Q000302:isolation & purification / Q000378:metabolism; D002645:Chickens; D004527:Egg Proteins / Q000378:metabolism*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D026901:Membrane Transport Proteins; D008970:Molecular Weight; D011247:Pregnancy / Q000097:blood*; D012256:Riboflavin / Q000378:metabolism*; D013045:Species Specificity
D002352:Carrier Proteins; D004527:Egg Proteins; D026901:Membrane Transport Proteins; C019079:riboflavin-binding protein; D012256:Riboflavin