Prolonged expiratory apnoea (cyanotic 'breath-holding') in association with a medullary tumour.
From the age of four months to his sudden, unexpected death at 2 years 11 months, a child had severe cyanotic episodes attributed to cyanotic 'breath-holding' (prolonged expiratory apnoea). At postmortem he was found to have a previously undiagnosed gangliocytoma of the medulla, which had invaded the floor of the fourth ventricle and variably affected the 7th to 12th cranial-nerve nuclei.
Southall
D P
DP
Department of Paediatrics, Brompton Hospital, London.
Lewis
G M
GM
Buchanan
R
R
Weller
R O
RO
D001049:Apnea / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology*; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D002675:Child, Preschool; D005729:Ganglioneuroma / Q000473:pathology*; D006801:Humans; D008297:Male; D008526:Medulla Oblongata / Q000473:pathology*; D009361:Neoplasm Invasiveness