Lipid peroxidation in hypertrophic rat kidney.
During compensatory growth of kidney, microsomal lipid peroxidation is unchanged in the hypertrophy phase and is doubled in a period of hyperplasia. The maximum lipid peroxidation is preceded by a 2-fold increase in the content of cytochrome P-450. Both in microsomes and cytosol, intense peroxidation of lipids is accompanied by a decrease in glutathione content.
Department of Biochemistry, Medical School, Warsaw, Poland.
T
T
Laskowska-Klita
M
M
Szumiło
D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D006984:Hypertrophy / Q000378:metabolism; D007668:Kidney / Q000378:metabolism* / Q000473:pathology; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008297:Male; D008861:Microsomes / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D008054:Lipid Peroxides; D003577:Cytochrome P-450 Enzyme System; D005978:Glutathione; D001205:Ascorbic Acid