[Primary lymphedema in the nephrotic syndrome: case report].
The aim of this case report is to discuss possible connections between the development of a hypoproteinaemic oedema due to the nephrotic syndrome and the occurrence of lymphoedema. Two patients (a three year-old girl and a seven year-old boy) developed lymphoedema of one leg one year after the onset of the nephrotic syndrome. The case of the six year-old girl is presented. Malignancy was excluded by clinical investigation. Direct lymphography failed to show any peripheral lymph-vessels; indirect lymphography (i.c. infusion of a newly-developed contrast medium) revealed hypoplasia of the peripheral lymph-collectors. The development of lymphoedema 12-18 months after the appearance of the nephrotic syndrome supports the hypothesis that the increase in extravascular fluid, which is caused by a reduced oncotic pressure in the plasma, may trigger off the development of lymphoedema if there is a primary defect of the lymphatic system.
Universitäts-Kinderklinik, Wien.
U
U
Wagner
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E
Balzar
A
A
Khoss
H
H
Partsch
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007019:Hypoproteinemia / Q000209:etiology; D008209:Lymphedema / Q000000981:diagnostic imaging / Q000209:etiology*; D008220:Lymphography; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications*; D012008:Recurrence
Primäres Lymphödem bei nephrotischem Syndrom: Fallbericht.