Congenital malformations and twinning in a breeding colony of Old World monkeys.
Clinical and necropsy records of malformations in Old World monkeys were compiled. The numbers of malformations and birth incidence rate for each species were: Rhesus macaque (Macaca mulatta) 3 (1.02%); Cynomolgus macaque (Macaca fascicularis) 11 (1.62%); Stumptail macaque (Macaca arctoides) 3 (1.55%); African green monkey (Cercopithecus aethiops) 4 (1.5%). There was one pair of rhesus twins (twinning rate: 0.34%). Cardiovascular and central nervous system lesions accounted for 55% of all malformations. Only two of the malformations were in inbred infants. Nine of twenty-one colony-born malformed infants lived 24 hours or more.
Jerome
C P
CP
Department of Comparative Medicine, Bowman Gray School of Medicine, Winston-Salem, NC 27103.
D000818:Animals; D002520:Cercopithecidae; D000013:Congenital Abnormalities / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D005260:Female; D005298:Fertility; D008251:Macaca; D008297:Male; D008992:Monkey Diseases / Q000151:congenital* / Q000235:genetics / Q000473:pathology