[The REM syndrome--alternative therapeutic possibilities].
Chloroquine and chloroquine derivatives have proved successful in the therapy of REM syndrome (REMS). Alternative treatment schedules have not been described so far. In a female Patient, chloroquine therapy had to be discontinued because of ophthalmologic contraindication. PUVA therapy induced complete remission, whereas dapsone alone only led to incomplete improvement. Additional UV radiation--mainly UV-A--had a positive effect. Chloroquine contraindication justifies the use of these alternative therapeutic approaches to REMS.
Klinik für Hautkrankheiten, Medizinischen Akademie Carl Gustav Carus Dresden.
G
G
Wozel
J
J
Barth
D000328:Adult; D002738:Chloroquine / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D004890:Erythema / Q000188:drug therapy*; D005260:Female; D006801:Humans; D009077:Mucins / Q000378:metabolism*; D011701:PUVA Therapy
D009077:Mucins; D002738:Chloroquine; D003622:Dapsone
REM-Syndrom (REMS)--Alternative Therapiemöglichkeiten.