ECT in primary and secondary depression.
The response of depressive symptoms to ECT was studied in 58 subjects who met DSM-III criteria for major depression. For data analysis, the sample was divided by diagnosis into categories of primary unipolar depression, bipolar depression, and secondary depression. Only 56% of the secondary depression group had a partial or complete remission of depressive symptoms, but 91% of the primary unipolar group and 100% of the primary bipolar group improved. Subdividing the secondary depression group by primary diagnosis revealed a differential response, with alcoholism and schizophrenia having the most favorable outcomes.
Zorumski
C F
CF
Rutherford
J L
JL
Burke
W J
WJ
Reich
T
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications / Q000523:psychology; D001714:Bipolar Disorder / Q000523:psychology / Q000628:therapy; D003866:Depressive Disorder / Q000209:etiology / Q000523:psychology / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications / Q000523:psychology; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications; D012565:Schizophrenic Psychology