[Effect of gangliosides on the resistance of mice to the rabies virus].
The survival of animals has been studied after their infection with a mixture of rabies virus and gangliosides isolated from various organs. It has been found that virus incubation with a summarized fraction of cerebral gangliosides increased considerably the survival of animals. At the same time it was shown that gangliosides from cattle spleen and red blood cells taken in the same proportions as cerebral gangliosides, do not have any protective effect. The in vivo study of the antiviral ganglioside activity has been performed.
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D000818:Animals; D001923:Brain Chemistry; D004912:Erythrocytes / Q000032:analysis; D005260:Female; D005732:Gangliosides / Q000276:immunology* / Q000302:isolation & purification; D008297:Male; D051379:Mice; D011818:Rabies / Q000276:immunology*; D013154:Spleen / Q000032:analysis
D005732:Gangliosides
Issledovanie deĭstviia nekotorykh gangliozidov na rezistentnost' organizma mysheĭ k virusu beshenstva.