[Detection of circulating immune complexes in the serum of pregnant patients in normal pregnancy and in pregnancy-induced hypertension using precipitation by polyethylene glycol].
30 non-pregnant women, 250 women with normal pregnancy and 130 women with pregnancy induced hypertension (PIH) have been examined to show the presence of circulating immune complexes in serum. The immune complex concentration in normal pregnancy shows a rapid decrease from 6th up to 12th gestational week, then a plateau near to 35th week and further a slight increase. Decrease and increase can be described only with hypothesis. The immune complex concentration in 1st and 3rd trimenon of normal pregnancy was significantly different to non-pregnant women. As like as the group of normal pregnancies the women with PIH showed an increase of immune complex concentration on a higher level, but the differences between both groups were not significant.
I
I
Reincke
W
W
Straube
V
V
Briese
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis*; D011232:Chemical Precipitation; D005260:Female; D005865:Gestational Age; D006801:Humans; D006973:Hypertension / Q000276:immunology*; D011092:Polyethylene Glycols; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000276:immunology*
D000936:Antigen-Antibody Complex; D011092:Polyethylene Glycols
Untersuchungen zum Nachweis zirkulierender Immunkomplexe im Serum Gravider während der ungestörten Schwangerschaft und bei schwangerschaftsinduzierter Hypertonie (SIH) mittels der Präzipitation durch Polyethylenglykol.