Short-term feeding-related changes in mediodorsal hypothalamic catecholamine release.
Release of noradrenaline (NA), adrenaline (A) and dopamine (DA) was measured in vivo per minute before and after food presentation in satiated rats that had a cannula in the mediodorsal hypothalamic area (MDH). Release of NA was significantly increased above baseline during a period of a few minutes in which feeding took place. In the period following feeding there were peaks in the release of both NA and A. In DA release no changes were observed. Since a statistical correlation between release of NA or A and locomotor activity was not found, it is suggested that the increased release of NA and A is specifically related to food-motivated behavior.
N
N
Kruissink
J
J
Van der Gugten
J L
JL
Slangen
D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D004435:Eating; D004837:Epinephrine / Q000378:metabolism; D007033:Hypothalamus, Middle / Q000378:metabolism / Q000502:physiology*; D008297:Male; D009043:Motor Activity; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D002395:Catecholamines; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine