Effects of cytochrome b5 on aniline hydroxylation catalyzed by a reconstituted system containing acetone or 2,2'-bipyridine.
Cytochrome b5 did not exert any effect on NADPH-dependent aniline hydroxylation in the absence of acetone or 2,2'-bipyridine, whereas cytochrome b5 exhibited a stimulatory effect on the reaction in the presence of acetone or 2,2'-bipyridine. In addition, cytochrome b5 did not have any significant effect on the cumene hydroperoxide-dependent reaction in the presence of acetone or 2,2'-bipyridine.
M
M
Kitada
N
N
Yamaguchi
T
T
Rikihisa
Y
Y
Kanakubo
H
H
Kitagawa
D015082:2,2'-Dipyridyl / Q000494:pharmacology*; D000096:Acetone / Q000494:pharmacology*; D000814:Aniline Compounds / Q000378:metabolism*; D000818:Animals; D003573:Cytochrome b Group / Q000494:pharmacology*; D015786:Cytochromes b5; D006900:Hydroxylation; D009249:NADP / Q000378:metabolism; D010084:Oxidation-Reduction; D011725:Pyridines / Q000494:pharmacology*; D051381:Rats
D000814:Aniline Compounds; D003573:Cytochrome b Group; D011725:Pyridines; D000096:Acetone; D009249:NADP; D015082:2,2'-Dipyridyl; D015786:Cytochromes b5; C023650:aniline