[Diagnosis and therapy of Churg-Strauss allergic granulomatosis].
Three cases of allergic granulomatosis (Churg-Strauss syndrome) are reported. The patients all presented 2-10 years after the onset of pulmonary symptoms with a mononeuritis multiplex, accompanied by sharp pain in the extremities involved. In one patient, the neurological findings improved under treatment with corticoids and cyclophosphamide; the other two patients responded to treatment with thioguanine and cytarabine. In the first patient, the diagnosis was confirmed by a biopsy specimen of the sural nerve.
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Berlit
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Storch
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Schmitt
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D001369:Axons / Q000648:ultrastructure; D003520:Cyclophosphamide / Q000627:therapeutic use; D003561:Cytarabine / Q000627:therapeutic use; D003711:Demyelinating Diseases / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009468:Neuromuscular Diseases / Q000188:drug therapy / Q000473:pathology*; D013497:Sural Nerve / Q000473:pathology; D013577:Syndrome; D013866:Thioguanine / Q000627:therapeutic use; D014657:Vasculitis / Q000473:pathology
D000305:Adrenal Cortex Hormones; D000936:Antigen-Antibody Complex; D003561:Cytarabine; D003520:Cyclophosphamide; D013866:Thioguanine
Diagnose und Therapie der allergischen Granulomatose Churg-Strauss.