Neurocysticercosis: surgical and medical management with praziquantel.
Eight cases of neurocysticercosis were encountered at the two major neurological centers affiliated with McGill University in Montreal in 4 years. All patients were immigrants who had been in Canada for a period of 1 to 18 years and came from South America (three cases), Haiti (three cases), and Greece (two cases). Five patients had parenchymal cysts and presented with epilepsy; three had the racemose form and presented with hydrocephalus. Four patients with parenchymal cysts were treated by removal of the cysticercus and did well. One patient with numerous cysts was treated with praziquantel with good clinical and radiological results. Two patients with the racemose form were treated by cyst aspiration, cerebrospinal fluid (CSF) diversion, and praziquantel and did well. Another patient with the racemose form, seen before the advent of praziquantel, died of cysticercosis infection. Neurocysticercosis is not uncommon in the immigrant population of large North American cities. Single symptomatic cysts can be evacuated surgically with good results; multiple parenchymatous cysts can be treated with praziquantel. Patients with the racemose form who are treated with CSF diversion and praziquantel do well, although those who are only treated surgically die of their disease.
Leblanc
R
R
Knowles
K F
KF
Melanson
D
D
MacLean
J D
JD
Rouleau
G
G
Farmer
J P
JP
D000328:Adult; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D002557:Cerebrospinal Fluid Shunts; D003399:Craniotomy; D003551:Cysticercosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
D011223:Praziquantel