A comparison of intravenous hydrocortisone, methylprednisolone, and dexamethasone in acute bronchial asthma.
The short-term airway response of 14 subjects with severe asthma to equivalent low doses of intravenous hydrocortisone, methylprednisolone, and dexamethasone was examined. Overall the subjects improved without any significant differences between the three groups in subject age, baseline percent predicted FEV1, or percent predicted FEV1 at 3, 6, 9, 24, 48, and 72 hours (P greater than .05).
Sue
M A
MA
Kwong
F K
FK
Klaustermeyer
W B
WB
D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D003907:Dexamethasone / Q000008:administration & dosage* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005541:Forced Expiratory Volume; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage* / Q000627:therapeutic use; D007275:Injections, Intravenous; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D011897:Random Allocation
D003907:Dexamethasone; D006854:Hydrocortisone; D008775:Methylprednisolone