Vinpocetine effects on cognitive impairments produced by flunitrazepam.
The effects of pre-treatment with vinpocetine 40 mg, on flunitrazepam-induced impairment of memory, were studied in 8 normal volunteers. Tests of Critical Flicker Fusion Threshold, a Sternberg Memory Scanning Task, along with subjective ratings of drug action were used. Drug effects were found to be modest. Treatment with vinpocetine was associated with improvements in short-term memory processes.
Bhatti
J Z
JZ
Human Psychopharmacology Research Unit, University of Leeds, U.K.
Hindmarch
I
I
D000328:Adult; D005260:Female; D005425:Flicker Fusion / Q000187:drug effects; D005445:Flunitrazepam / Q000494:pharmacology; D006801:Humans; D008568:Memory / Q000187:drug effects; D008569:Memory Disorders / Q000139:chemically induced / Q000517:prevention & control*; D012890:Sleep / Q000187:drug effects; D014748:Vinca Alkaloids / Q000494:pharmacology / Q000627:therapeutic use*
D014748:Vinca Alkaloids; C013983:vinpocetine; D005445:Flunitrazepam