Treatment of nonspecific diarrhea with metronidazole in rhesus macaques.
Nonspecific diarrhea was successfully treated with metronidazole in 76% (13/17) of cases in adult rhesus macaques (Macaca mulatta). Effective treatment was achieved by oral administration of metronidazole daily at a low dose of 250 mg for at least eight days or at high daily doses of 500-1,500 mg for one to four days. Minimal effective total dose was 1500 mg. Apart from occasional vomiting, no side effects were observed.
Wisconsin Regional Primate Research Center, Madison.
V
V
Reinhardt
W D
WD
Houser
D A
DA
Sadoff
J
J
Scheffler
S G
SG
Eisele
M J
MJ
Hempel
D000818:Animals; D003967:Diarrhea / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D008253:Macaca mulatta; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D008992:Monkey Diseases / Q000188:drug therapy*
D008795:Metronidazole