Neuropathology of Seckel syndrome in fetal stage with evidence of intrauterine developmental retardation.
Marked intrauterine developmental retardation in a fetal case of Seckel syndrome was morphologically defined in the 29th week of gestation by comparing with a large number of length-matched and age-matched controls. Telencephalic micrencephaly with reduced neuroblast production, retarded functional differentiation of the pituitary gland, and generalized hypotrophy with craniofacial stigmata were observed.
Department of Neuropathology, Universität Göttingen, Federal Republic of Germany.
A
A
Hori
K
K
Tamagawa
S W
SW
Eber
M
M
Westmeier
I
I
Hansmann
D000015:Abnormalities, Multiple / Q000473:pathology*; D001921:Brain / Q000002:abnormalities / Q000254:growth & development* / Q000473:pathology; D005260:Female; D005317:Fetal Growth Retardation / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008831:Microcephaly / Q000473:pathology*; D011247:Pregnancy; D013577:Syndrome