Cerebrospinal fluid findings in healthy siblings of multiple sclerosis patients.
We studied six families in which two or more siblings were affected by MS. CSF analysis was available on 37 subjects: 9 with MS and 28 healthy siblings. Five of 28 healthy siblings (17.8%) had abnormal CSF immunoglobulins. These findings affect family studies of MS.
Duquette
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P
Charest
L
L
D000328:Adult; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid* / Q000235:genetics; D012709:Serum Albumin / Q000032:analysis
D007074:Immunoglobulin G; D012709:Serum Albumin