Decreased ketonaemia in the monosodium glutamate-induced obese rats.
Plasma concentrations of total ketone bodies, acetoacetate (AcAc) and 3-hydroxybutyrate (3-OHBA) in monosodium glutamate (MSG)-induced obese rats were measured. MSG-treated rats showed higher Lee's indices, shorter naso-anal and tail length, and a more marked intraperitoneal fat deposition than control rats. Plasma concentrations of glucose, free fatty acid, triglyceride and phospholipids were significantly increased in the MSG-treated rats as compared to the control rats (24 weeks-old). Plasma levels of total ketone bodies, AcAc and 3-OHBA were all decreased in the MSG-treated rats as compared to control rats. The ratio, 3-OHBA/AcAc in the MSG-treated rats were not different from those in the control rats.
T
T
Nakai
T
T
Tamai
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H
Takai
S
S
Hayashi
R
R
Fujiwara
S
S
Miyabo
D020155:3-Hydroxybutyric Acid; D000090:Acetoacetates / Q000097:blood; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D005971:Glutamates; D006885:Hydroxybutyrates / Q000097:blood; D007657:Ketone Bodies / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood* / Q000139:chemically induced; D010743:Phospholipids / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains; D012970:Sodium Glutamate; D014280:Triglycerides / Q000097:blood
D000090:Acetoacetates; D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D005971:Glutamates; D006885:Hydroxybutyrates; D007657:Ketone Bodies; D010743:Phospholipids; D014280:Triglycerides; C016635:acetoacetic acid; D002784:Cholesterol; D020155:3-Hydroxybutyric Acid; D012970:Sodium Glutamate