An evaluation of the acidified glycerol lysis test.
The acidified glycerol lysis test (AGLT), as a screening procedure for spherocytosis, has been assessed for sensitivity and specificity. AGLT identified 24 of 26 subjects with hereditary spherocytosis and produced 19 abnormal AGLTs out of a total of 52 normal blood donors. The claims for the test as being both 100% sensitive and specific could not be confirmed.
Rutherford
C J
CJ
Postlewaight
B F
BF
Hallowes
M
M
D005069:Evaluation Studies as Topic; D005990:Glycerol; D006403:Hematologic Tests; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D013103:Spherocytosis, Hereditary / Q000175:diagnosis*
D005990:Glycerol