Early treatment by plasmapheresis in a woman with multiple abortions and the rare blood group p.
Women with the rare blood group p are known to have an increased rate of abortions. The case of a 36-year-old woman is presented who had had 7 spontaneous abortions in the first trimester and no live child. When treated by plasma exchange begun early in pregnancy and continued until the 29th week, she delivered a normal child. Time to begin, amount and length of time necessary to continue plasma exchange in these patients are considered. In addition, the question of which fraction of the anti-PP1Pk could be responsible for abortion is discussed. To our knowledge, this is the first case of a woman of p phenotype with no live children but with multiple abortions treated by this method, which should be seriously considered in similar cases.
Shechter
Y
Y
Department of Hematology and Blood Bank, Rambam Medical Center, Haifa Israel.
Timor-Tritsch
I E
IE
Lewit
N
N
Sela
R
R
Levene
C
C
D000026:Abortion, Habitual / Q000628:therapy*; D000328:Adult; D001789:Blood Group Antigens; D004394:Dydrogesterone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010127:P Blood-Group System; D010956:Plasmapheresis; D011247:Pregnancy; D011248:Pregnancy Complications; D011261:Pregnancy Trimester, First; D013203:Staphylococcal Infections / Q000150:complications; D013997:Time Factors
D001789:Blood Group Antigens; D010127:P Blood-Group System; D004394:Dydrogesterone