[Sex hormone receptors in the hypothalamus and their role in the sexual differentiation of the brain of male rats].
The content of receptors to estradiol and testosterone was determined in cytoplasmic and nuclear fractions of hypothalamus and brain cortex of male rats in the early postnatal period. Receptors to both estradiol and testosterone were revealed in cytosol and nuclear fractions, with the decrease in their concentration observed from days 1 to 5. The data obtained demonstrate that receptors to sexual hormones take part in the brain differentiation and regulation of hypophysis gonadotropic function by male or female type.
Shishkina
I V
IV
Babichev
V N
VN
Ozol'
L Iu
LIu
D000818:Animals; D000831:Animals, Newborn; D002467:Cell Nucleus / Q000032:analysis; D002540:Cerebral Cortex / Q000254:growth & development; D003600:Cytosol / Q000032:analysis; D004958:Estradiol / Q000502:physiology*; D007031:Hypothalamus / Q000254:growth & development*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D051381:Rats; D011944:Receptors, Androgen; D011959:Receptors, Estradiol / Q000032:analysis* / Q000502:physiology; D011960:Receptors, Estrogen / Q000032:analysis*; D011987:Receptors, Steroid / Q000032:analysis* / Q000502:physiology; D012741:Sexual Maturation; D013739:Testosterone / Q000502:physiology*
D011944:Receptors, Androgen; D011959:Receptors, Estradiol; D011960:Receptors, Estrogen; D011987:Receptors, Steroid; D013739:Testosterone; D004958:Estradiol; D007986:Luteinizing Hormone
Retseptory k polovym gormonam v gipotalamuse i ikh rol' v polovoĭ differentsirovke mozga u krys-samtsov.