[Isolation of Ureaplasma urealyticum from patients with chronic prostatitis].
Ureaplasma urealyticum has been considered to be a pathogen of nongonococcal urethritis. To elucidate the pathogenicity of this microorganism in chronic prostatitis, U. urealyticum was isolated from patients with chronic prostatitis and prostatodynia. Using the Taylor-Robinson's method, U. urealyticum was detected in expressed prostatic secretion (EPS) or urine voided after prostatic massage (VB3) in 40 (41.2%) out of 97 patients with chronic prostatitis and 6 (20.0%) out of 30 patients with prostatodynia. Seventeen patients with U. urealyticum-positive chronic prostatitis, 13 of whom had failed to respond to the treatment by other antimicrobial agents, were treated with minocycline. In 16 (94.1%) of the 17 patients, U. urealyticum was eradicated and in 14 patients (82.4%), the elevated white blood cell count was markedly lowered in EPS or VB3. U. urealyticum may prove to be an etiological microorganism of chronic prostatitis.
Department of Urology, School of Medicine, Kanazawa University.
T
T
Sugata
M
M
Ohkawa
T
T
Nakashima
S
S
Tokunaga
A
A
Ikeda
S
S
Kawaguchi
H
H
Hisazumi
S
S
Fujita
D002908:Chronic Disease; D006801:Humans; D008297:Male; D008911:Minocycline / Q000627:therapeutic use; D010146:Pain / Q000382:microbiology; D011469:Prostatic Diseases / Q000382:microbiology; D011472:Prostatitis / Q000382:microbiology*; D014509:Ureaplasma / Q000187:drug effects / Q000302:isolation & purification*
D008911:Minocycline