Calcium and calcitonin responses to calcium infusion in type I diabetes mellitus.
We studied calcium and calcium and calcitonin responses to intravenous calcium infusion (3 mg of elemental calcium/kg of body weight in 10 minutes) in 21 type I diabetic males and 17 age-matched normal males. Baseline total calcium, parathyroid hormone and calcitonin levels were normal in the diabetic group, but ionized calcium was lowered. Cortical bone status and osteocalcin levels were normal, suggesting a normal osteoblastic function. Total calcium and ionized calcium responses to calcium infusion were lowered in the diabetic group. Despite these lowered calcaemic responses, calcitonin secretion was normal.
Department of Internal Medicine, Valdecilla Hospital School of Medicine, Santander, Spain.
J A
JA
Amado
C
C
Gomez
S
S
Obaya
M
M
Otero
J
J
Gonzalez-Macias
D000328:Adult; D002116:Calcitonin / Q000378:metabolism*; D002118:Calcium / Q000008:administration & dosage / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000378:metabolism*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male
D002116:Calcitonin; D002118:Calcium