Effect of allopurinol on the first-pass metabolism of 6-mercaptopurine in the rat.
Faculty of Pharmaceutical Sciences, Nagasaki University, Japan.
H
H
Sasaki
K
K
Tsuru
J
J
Nakamura
R
R
Konishi
J
J
Shibasaki
D000284:Administration, Oral; D000493:Allopurinol / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D007275:Injections, Intravenous; D008099:Liver / Q000201:enzymology; D008297:Male; D015122:Mercaptopurine / Q000097:blood / Q000493:pharmacokinetics*; D051381:Rats; D011919:Rats, Inbred Strains; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors
D000493:Allopurinol; D015122:Mercaptopurine; D014969:Xanthine Oxidase