Cytogenetic investigation in 300 couples with recurrent fetal wastage.
A series of 300 couples with reproductive failure, i.e. 100 couples with a history of 2-4 spontaneous abortions (lot 1) and 200 couples with abortions and one or several dead plurimalformed children (lot 2) were cytogenetically investigated. The incidence of major chromosomal aberrations was 7% (lot 1) and 5.5% (lot 2) and minor aberrations 13% (lot 1) and 5% (lot 2). The mean percentage of chromosmal aberrations in the 300 couples was 6.03%, a figure which is close to the one reported in the literature of the recent years, i.e.6.1%.
Ioan
D
D
C. I. Parhon, Institute of Endocrinology, Bucharest, Romania.
Dumitriu
L
L
Muşeţeanu
P
P
Ioaniţiu
D
D
Pop
T
T
Maximilian
C
C
D000026:Abortion, Habitual / Q000235:genetics*; D002869:Chromosome Aberrations; D005260:Female; D005313:Fetal Death / Q000235:genetics*; D006801:Humans; D008297:Male; D011247:Pregnancy