Effect of fatty acids on aflatoxin production by Aspergillus parasiticus.
The effect of saturated and unsaturated fatty acids on aflatoxin production was studied in a synthetic medium. The aflatoxin production decreased (10-75%) in the presence of lauric acid and palmitic acid but the addition of behenic and sebacic acid stimulated aflatoxin production by 125-541%. Linolenic and linoleic acids effected aflatoxin production and mycelium growth. An 34-fold increase in aflatoxin production was observed with 50 mM linoleic acid. An inverse relationship was observed between aflatoxin production and mycelium mass, irrespective of the nature of the fatty acid.
R P
RP
Tiwari
V
V
Mittal
G
G
Singh
T C
TC
Bhalla
S S
SS
Saini
D V
DV
Vadehra
D000348:Aflatoxins / Q000096:biosynthesis*; D001230:Aspergillus / Q000254:growth & development / Q000378:metabolism*; D003470:Culture Media; D003652:Decanoic Acids / Q000494:pharmacology; D003998:Dicarboxylic Acids; D005227:Fatty Acids / Q000494:pharmacology*; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D007850:Lauric Acids / Q000494:pharmacology; D008041:Linoleic Acids / Q000494:pharmacology; D008042:Linolenic Acids / Q000494:pharmacology; D009227:Myristic Acids / Q000494:pharmacology; D009829:Oleic Acids / Q000494:pharmacology; D010169:Palmitic Acids / Q000494:pharmacology
D000348:Aflatoxins; D003470:Culture Media; D003652:Decanoic Acids; D003998:Dicarboxylic Acids; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D007850:Lauric Acids; D008041:Linoleic Acids; D008042:Linolenic Acids; D009227:Myristic Acids; D009829:Oleic Acids; D010169:Palmitic Acids; C011107:sebacic acid; C007547:behenic acid