Hemolytic uremic-like syndrome in two horses.
A syndrome characterized clinically by oliguria, progressive severe azotemia, and edema of the abdomen and groin was seen in 2 horses. Treatment with fluids, diuretics, and corticosteroids administered intravenously was ineffective, and the horses were euthanatized. Microscopically, there was severe necrotizing angiopathy with profuse fibrin deposition in renal glomeruli and sinusoids of peripheral lymph nodes. The signs observed in the horses resembled hemolytic-uremic syndrome in human beings.
Laboratory of Large Animal Pathology, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.
C F
CF
Morris
J L
JL
Robertson
P C
PC
Mann
S
S
Clark
T J
TJ
Divers
D000818:Animals; D006463:Hemolytic-Uremic Syndrome / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D007668:Kidney / Q000473:pathology; D008297:Male