Cutaneous microthrombi: a histologic clue to the diagnosis of hypereosinophilic syndrome.
Hypereosinophilic syndrome is a rare systemic disease that frequently has cutaneous lesions. Past reviews of the histopathology of the skin lesions have revealed a nonspecific dermal infiltrate with occasional eosinophils as a constant finding. A case of hypereosinophilic syndrome with cutaneous manifestations, in which the skin biopsy demonstrated multiple cutaneous microthrombi, is reported. The diagnostic and prognostic significance of this finding is discussed.
Fitzpatrick
J E
JE
Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colorado 80045-6000.
Johnson
C
C
Simon
P
P
Owenby
J
J
D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*; D013577:Syndrome; D013927:Thrombosis / Q000473:pathology*