Assessment of nasal airway patency: a comparison of four methods.
Two established methods (active posterior and passive anterior rhinomanometry) and 2 new methods (peak nasal inspiratory flow rate and apparent nasal volume) were used in 12 volunteers to assess the patency of the nasal airways under each of 4 conditions (baseline, post-exercise, nasal histamine and nasal cocaine). All methods showed the congestant effect of histamine but the peak nasal inspiratory flow and apparent nasal volume techniques were more sensitive to the 'decongesting' manoeuvres, (exercise and cocaine). Useful objective quantitative data on the patency of the nasal airways and its changes in response to stimuli can be obtained by simple, cheap and readily available techniques. Subjective sensation is a poor guide to the state of patency of the nasal airways.
Gleeson
M J
MJ
Youlten
L J
LJ
Shelton
D M
DM
Siodlak
M Z
MZ
Eiser
N M
NM
Wengraf
C L
CL
D000328:Adult; D000402:Airway Obstruction / Q000175:diagnosis*; D000403:Airway Resistance / Q000187:drug effects; D003042:Cocaine / Q000494:pharmacology; D006632:Histamine / Q000031:analogs & derivatives / Q000494:pharmacology; D006801:Humans; D008365:Manometry; D008875:Middle Aged; D005082:Physical Exertion; D012123:Pulmonary Ventilation / Q000187:drug effects
D006632:Histamine; D003042:Cocaine; C027556:histamine phosphate