[Chronopharmacological characteristics of the action of dehydrocholic acid on bile formation].
Peculiarities of the liver response to dehydrocholic acid, conditioned by the time of its administration during the day and by the seasons of the year were revealed in experiments on random bred mature white rats. The dependence of this reaction on the time factor was manifested in all the main indicators of cholopoiesis--in the rate of bile secretion, synthesis and secretion of bile acids and bilirubin, cholesterol excretion.
Skakun
N P
NP
Davydovich
O V
OV
D000818:Animals; D001646:Bile / Q000032:analysis / Q000187:drug effects* / Q000378:metabolism; D001647:Bile Acids and Salts / Q000032:analysis; D001663:Bilirubin / Q000032:analysis; D002784:Cholesterol / Q000032:analysis; D002940:Circadian Rhythm / Q000187:drug effects; D003685:Dehydrocholic Acid / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D051381:Rats; D012621:Seasons; D013997:Time Factors
D001647:Bile Acids and Salts; D002784:Cholesterol; D003685:Dehydrocholic Acid; D001663:Bilirubin
Khronofarmakologicheskie osobennosti deĭstviia degidrokholevoĭ kisloty na zhelcheobrazovanie.