Hb J-Antakya or alpha 2 beta (2)65(E9)Lys----Met in a Turkish family and Hb complutense or alpha 2 beta (2)127(H5)Gln----Glu in a Spanish family; correction of a previously published identification.
Almost 10 years ago we reported in this journal the characterization of Hb Hacettepe or alpha 2 beta (2)127(H5)Gln----Glu. Unfortunately, we have to conclude that the original characterization of this Turkish variant was in error. The corrected data are presented in this short communication. The variant (alpha 2 beta (2)65(E9)Lys----Met) was (re)named Hb J-Antakya, after the city where the family resides. An abnormal Hb, observed in a Spanish family and named Hb Complutense, had the beta 127 Gln----Glu substitution, erroneously assigned to the Turkish variant.
Huisman
T H
TH
Wilson
J B
JB
Kutlar
A
A
Yang
K G
KG
Chen
S S
SS
Webber
B B
BB
Altay
C
C
Martinez
A V
AV
D000595:Amino Acid Sequence; D002845:Chromatography; D002851:Chromatography, High Pressure Liquid; D006448:Hemoglobin J / Q000032:analysis; D006455:Hemoglobins, Abnormal / Q000032:analysis; D006801:Humans; D010446:Peptide Fragments / Q000302:isolation & purification; D013030:Spain; D014357:Trypsin; D014421:Turkey
D006455:Hemoglobins, Abnormal; D010446:Peptide Fragments; C048991:hemoglobin Complutense; D006448:Hemoglobin J; C048990:hemoglobin J Antakya; D014357:Trypsin