Prevalence in human beings of antibodies to Chlamydia IOL-207, an atypical strain of chlamydia.
Samples of serum from 18353 persons from the U.K. and abroad, were tested for type-specific antibodies to Chlamydia spp. Antibodies to an atypical strain, Chlamydia IOL-207, were detected in each population tested. Overall, the prevalence of these antibodies (19.9%) was similar to that of antibodies to C. trachomatis (21.6%). In the U.K., antibodies to C. IOL-207 were rare in children under the age of 5 years but became more common with increasing age. In adults the prevalence of these antibodies increased annually between 1979 and 1984. Antibodies to C. IOL-207 were not associated with sexually transmitted disease and only rarely with ocular disease. Their association with a common complaint such as mild respiratory illness is postulated. The presence of these antibodies within a population may lead to the over-diagnosis of C. trachomatis infections or psittacosis if only genus-specific serological tests are used.
Forsey
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Darougar
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Treharne
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JD
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000907:Antibodies, Bacterial / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D002689:Chlamydia / Q000276:immunology*; D002690:Chlamydia Infections / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000276:immunology; D005128:Eye Diseases / Q000276:immunology / Q000382:microbiology; D005260:Female; D005831:Genital Diseases, Female / Q000382:microbiology; D005832:Genital Diseases, Male / Q000382:microbiology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M