Alpha- and gamma tocopherol concentrations in human serum.
Vitamin E (alpha- and gamma-tocopherol) and total lipid concentrations were determined in the serum of 451 healthy human male and female subjects ranging in age from 19 to 70 years. Mean serum alpha-tocopherol concentration (microgram/ml) was 8.82 +/- 2.84 (SD) and gamma-tocopherol concentration was 1.35 +/- 0.70. The concentration of alpha-tocopherol increased significantly with age, as well as with total lipid; gamma-tocopherol concentration remained unchanged with age. The data also indicated that subjects with higher serum alpha-tocopherol had lower gamma-tocopherol levels and vice versa for subjects with higher gamma levels. A close interrelationship and competition appeared to exist between these two vitamers.
W A
WA
Behrens
R
R
Madère
D000328:Adult; D000368:Aged; D000375:Aging; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D014810:Vitamin E / Q000097:blood*
D008055:Lipids; D014810:Vitamin E