Ankyloblepharon associated with systemic 5-fluorouracil treatment.
A 59-year-old man undergoing systemic 5-fluorouracil treatment for metastatic adenocarcinoma of the stomach developed ocular lesions consisting of bilateral conjunctival ulcers and ulcerative blepharitis leading to ankyloblepharon. Ophthalmologists should be cognizant of potential ocular side effects of chemotherapy, in order to institute appropriate changes in treatment.
Insler
M S
MS
LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans 70112.
Helm
C J
CJ
D000230:Adenocarcinoma / Q000188:drug therapy; D001762:Blepharitis / Q000139:chemically induced / Q000150:complications; D005141:Eyelid Diseases / Q000139:chemically induced*; D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012883:Skin Ulcer / Q000139:chemically induced / Q000150:complications; D013274:Stomach Neoplasms / Q000188:drug therapy
D005472:Fluorouracil