[The role of immune factors in the coronary, chrono- and inotropic effects of adrenomimetics].
The experiments on dogs under chloralose and urethan anesthesia have shown that intracoronary injection of anticardiac immune serum caused inversion of coronary vascular reaction to adrenaline and isoprenaline and elimination of cardiogenic depressor hemodynamic reflex, without decreasing adrenomimetic inotropic effect. The administration of immune complexes (horse serum antigens--specific rabbit antibodies) produced biphasic coronary vascular reaction to adrenaline and decreased by half reflex hypotension, without changing chrono- and inotropic adrenaline effects.
S G
SG
Kaz'min
A A
AA
Moĭbenko
V F
VF
Sagach
O V
OV
Shablovskaia
D000818:Animals; D000936:Antigen-Antibody Complex / Q000276:immunology*; D003326:Coronary Circulation / Q000187:drug effects*; D004285:Dogs; D006339:Heart Rate / Q000187:drug effects*; D007106:Immune Sera / Q000276:immunology*; D009200:Myocardial Contraction / Q000187:drug effects*; D009206:Myocardium / Q000276:immunology; D013268:Stimulation, Chemical; D013566:Sympathomimetics / Q000494:pharmacology*
D000936:Antigen-Antibody Complex; D007106:Immune Sera; D013566:Sympathomimetics
Vliianie immunnykh vozdeĭstviĭ na koronarnye, khrono- i inotropnye éffekty adrenomimetikov.