From benign fasciculations and cramps to motor neuron disease.
Fasciculations and cramps may occur in motor neuron disease or as part of a more benign syndrome. A man with apparently benign fasciculations and cramps for 4 years developed progressive muscle weakness and wasting. Such a previously undocumented evolution of benign fasciculations and cramps to motor neuron disease may further implicate anterior horn cell dysfunction in the pathogenesis of muscle fasciculation-cramp syndromes.
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WS
Fleet
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Watson
D001284:Atrophy; D003714:Denervation; D004576:Electromyography; D005207:Fasciculation / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009120:Muscle Cramp / Q000150:complications*; D009132:Muscles / Q000473:pathology; D009422:Nervous System Diseases / Q000150:complications* / Q000209:etiology; D009468:Neuromuscular Diseases / Q000150:complications* / Q000473:pathology