Immature cerebellar astrocytoma in an infant.
A case of immature cerebellar astrocytoma in a 1 year and 4 months-old girl was described. The tumor consisted mainly of closely packed relatively uniform round cells with prominent intervening capillaries. Although tumor cells showed negative GFA (glial fibrillary acidic protein) immunoreactivity, demonstration of occasional bundles of 10 nm intermediate filaments (glial filaments) in cytoplasm on electron microscopy confirmed the diagnosis of astrocytoma. Differential diagnosis to hemangioblastoma, astroblastoma, and primitive neuroectodermal tumor was discussed.
Department of Laboratory Medicine, Akita University, School of Medicine, Japan.
M
M
Sageshima
H
H
Masuda
K
K
Kawamura
T
T
Shozawa
D001254:Astrocytoma / Q000473:pathology* / Q000648:ultrastructure; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008854:Microscopy, Electron