[Post-transfusion thrombopenia treated with gammaglobulins].
Thrombopenia and a haemorrhagic syndrome occurring on the eighth postoperative day were probably related to a post-transfusion purpura, confirmed by the discovery of antiplatelet antibodies not belonging to the PLA1 antigen system. The stabilization of this haemorrhage and a full recovery were obtained by giving high doses of intravenous human gammaglobulins. Blood replacement only rarely induces postoperative immuno-allergologic thrombopenia; heparin is the best known causative agent. It is concluded that platelets should never be given so long as the responsible agent is not formally identified.
J
J
Barre
M
M
Vinsonneau
C
C
Lelarge
J
J
Rendoing
J C
JC
Adjizian
G
G
Potron
D003937:Diagnosis, Differential; D005260:Female; D006493:Heparin / Q000494:pharmacology; D006622:Hip Prosthesis; D006801:Humans; D007116:Immunization, Passive; D008875:Middle Aged; D010974:Platelet Aggregation; D011183:Postoperative Complications; D013921:Thrombocytopenia / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D065227:Transfusion Reaction
D006493:Heparin
Thrombopénie post-transfusionnelle traitée par les gammaglobulines.