Fatal warm antibody autoimmune hemolysis with marked erythrocyte autoagglutination and liver necrosis.
We have described a fatal case of autoimmune hemolysis associated with marked organ ischemia and lactic acidosis. Serologically the case was unusual because of the marked autoagglutination due to a warm antibody. Red cell agglutination at normal body temperature may have contributed to massive liver necrosis, lactic acidosis, and death.
Waterbury
L
L
Parnes
H
H
Katz
R S
RS
D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology*; D001831:Body Temperature; D004903:Erythrocyte Aggregation / Q000209:etiology* / Q000401:mortality; D006461:Hemolysis; D006801:Humans; D008107:Liver Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009336:Necrosis
D001323:Autoantibodies