Metronidazole uptake in the cholesteatomatous membrane in chronic otitis media.
Previous investigations have demonstrated a good uptake of metronidazole in the middle ear mucosa. We have now presented a trial study in which there was also a significant uptake of metronidazole in the cholesteatomatous membranes of patients with chronic otitis media.
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S
Kristensen
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A
Juul
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A
Rosetzsky
D000328:Adult; D000368:Aged; D002781:Cholesteatoma / Q000150:complications / Q000188:drug therapy*; D002851:Chromatography, High Pressure Liquid; D004427:Ear Diseases / Q000150:complications / Q000188:drug therapy*; D004432:Ear, Middle / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000378:metabolism* / Q000627:therapeutic use; D008875:Middle Aged; D010033:Otitis Media / Q000188:drug therapy* / Q000209:etiology
D008795:Metronidazole