Method for the introduction of the reactive functional groups via cytidine residues and/or 3'-terminal of the nucleic acids.
A number of polyfunctional O-substituted hydroxylamines H2NO-R-X (X = SH; -NH2; -P(O) (OH)2; -COOH; etc.) were constructed and synthesized as a mean for the administration of the reactive functions through cytidines or into 3 -oxidised terminal of nucleic acids.
Institute of Molecular Biology, USSR Academy of Sciences, Moscow.
A M
AM
Kritsky
A R
AR
Khomutov
Yakovlev DYu
A G
AG
Gabibov
A G
AG
Rabinkov
R M
RM
Khomutov
D055598:Chemical Phenomena; D002621:Chemistry; D003562:Cytidine / Q000031:analogs & derivatives*; D006898:Hydroxylamines; D010084:Oxidation-Reduction; D012343:RNA, Transfer; D013329:Structure-Activity Relationship
D006898:Hydroxylamines; D003562:Cytidine; D012343:RNA, Transfer