The clearance of uranium after deposition of the nitrate and bicarbonate in different regions of the rat lung.
This study investigated the tissue distribution and excretion of uranium after its deposition as either the nitrate or bicarbonate in the three regions of the respiratory system of the rat. Results confirm the recommendations of ICRP that uranyl nitrate and bicarbonate should be treated as class D compounds; but imply that some of the parameters used in the ICRP lung model are not applicable to soluble uranium compounds.
National Radiological Protection Board, Chilton, Didcot, Oxon, UK.
M
M
Ellender
D000818:Animals; D001639:Bicarbonates / Q000493:pharmacokinetics*; D005260:Female; D008168:Lung / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution; D014501:Uranium / Q000493:pharmacokinetics*; D017974:Uranium Compounds; D014502:Uranyl Nitrate / Q000493:pharmacokinetics
D001639:Bicarbonates; D017974:Uranium Compounds; D014502:Uranyl Nitrate; C045395:uranium bicarbonate; D014501:Uranium