Obesity and hypertension.
Most hypertensive subjects are overweight, and as a consequence have an increased prevalence of hypercholesterolaemia, impaired glucose tolerance, and left ventricular hypertrophy. Reduction of the blood pressure by antihypertensive drugs without control of the obesity leaves these additional risk factors for cardiovascular disease uncorrected. Weight reduction has a substantial and sustained antihypertensive effect, removes or reduces the need for drug treatment, corrects the associated risk factors, and is clearly the more rational approach to management.
Ramsay
L E
LE
University Department of Therapeutics, Royal Hallamshire Hospital, Sheffield, UK.
D001835:Body Weight; D004038:Diet, Reducing; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D009765:Obesity / Q000628:therapy*; D010349:Patient Compliance; D011379:Prognosis; D012307:Risk Factors