Is microscopic colitis due to bile-salt malabsorption?
The cause of the recently described syndrome of chronic watery diarrhea associated with microscopic colitis is unknown. A patient appearing to have this disorder is described here. A major pathophysiologic role for bile-salt malabsorption in her, and perhaps other such patients, was suggested by her clinicopathologic response to cholestyramine.
Rampton
D S
DS
Newham General Hospital, London, United Kingdom.
Baithun
S I
SI
D000328:Adult; D001647:Bile Acids and Salts / Q000378:metabolism*; D002792:Cholestyramine Resin / Q000627:therapeutic use; D002908:Chronic Disease; D003092:Colitis / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007408:Intestinal Absorption
D001647:Bile Acids and Salts; D002792:Cholestyramine Resin