Effect of UV-irradiation, spleen cells and MLN cells on protective immunity against Angiostrongylus cantonensis infection in mice.
The UV-irradiated larvae of Angiostrongylus cantonensis were used for inducing immunity in mice. A single oral dose of 100 infective UV-irradiated larvae exposed for 5 min or 15 min induced 91% and 97% protection against subsequent infection. Adoptive protection against A. cantonensis could also be transferred by spleen and mesenteric lymph node cells obtained from vaccinated mice.
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VR
Kamath
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S
Menon
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DM
Renapurkar
D000801:Angiostrongylus / Q000276:immunology* / Q000528:radiation effects; D000818:Animals; D007110:Immunity, Active; D007114:Immunization; D007116:Immunization, Passive; D007814:Larva; D008198:Lymph Nodes / Q000276:immunology; D008297:Male; D008681:Metastrongyloidea / Q000276:immunology*; D051379:Mice; D009349:Nematode Infections / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D014466:Ultraviolet Rays