[Comparison of the effect of serotonin administered into the dorsal hippocampus on conditioned passive and active avoidance in rats].
It has been established that intrahippocampal bilateral injection of 5-HT in a dose of 2 micrograms prolonged the time of passive avoidance reflex retention, inhibiting the retrieval of active avoidance reflex and facilitating its extinction. The data obtained show the dependence of 5-HT effect on reinforcing and triggering properties of spatial-environmental and phasic conditioned stimuli. It is suggested that intrahippocampal 5-HT administration was responsible for the retrieval of traces of conditioned reinforced stimuli.
G G
GG
Gasanov
E M
EM
Melikov
G D
GD
Movsumov
D000818:Animals; D001362:Avoidance Learning; D003214:Conditioning, Classical; D006624:Hippocampus / Q000502:physiology*; D008297:Male; D008845:Microinjections; D051381:Rats; D011930:Reaction Time; D012701:Serotonin / Q000008:administration & dosage / Q000502:physiology*
D012701:Serotonin
Sravnenie deĭstviia serotonina, mikroapplitsirovannogo v dorsal'nyĭ gippokamp, na protsessy uslovnoreflektornoĭ pamiati passivnogo i aktivnogo izbeganiia u krys.