[The effect of a different protein supply with regard to quality and quantity on growth and serum growth hormone in weaned rats].
A two-factorially experiment was done over a period of 42 days using 32 male, weaned Sprague-Dawley rats in order to study the effect of insufficient protein supplementation, with regard to quantity and quality (13% protein in comparison to 18%, and an essential amino acid index of 64 in comparison to 92%, resp.), on weight development and serum growth hormone concentration. Qualitative protein deficiency had a greater adverse effect on weight development and feed utilization than did quantitative protein deficiency. Both test factors combined brought about the lowest body weight and poorest feed utilization. A lowered hematocrit value occurred only after quantitative protein deficiency. The serum urea concentration was elevated after protein deficiency due to poor quality protein; the serum protein concentration tended toward reduction in both the case of qualitative as well as in the case of qualitative-quantitative protein deficiency. After providing the animals poor quality protein, growth hormone levels in serum were reduced, whereas the concurrence of both factors of protein deficiency caused the growth hormone concentration in serum to rise to a value 4.2-fold of the control value.
Institut für Ernährungsphysiologie, Techn. Univ. München, Freising-Weihenstephan.
R
R
Jacob-Hammermann
M
M
Kirchgessner
H P
HP
Roth
D000821:Animal Feed; D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D001835:Body Weight; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D013006:Growth Hormone / Q000097:blood*; D006400:Hematocrit / Q000662:veterinary; D008297:Male; D011488:Protein Deficiency / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D051381:Rats; D011919:Rats, Inbred Strains; D014508:Urea / Q000097:blood
D001798:Blood Proteins; D004044:Dietary Proteins; D014508:Urea; D013006:Growth Hormone
Zum Einfluss einer hinsichtlich Qualität und Quantität unterschiedlichen Proteinversorgung auf Wachstum und Wachstumshormon im Serum entwöhnter Ratten.