Cutaneous microthrombi: a histologic clue to the diagnosis of hypereosinophilic syndrome.
Hypereosinophilic syndrome is a rare systemic disease that frequently has cutaneous lesions. Past reviews of the histopathology of the skin lesions have revealed a nonspecific dermal infiltrate with occasional eosinophils as a constant finding. A case of hypereosinophilic syndrome with cutaneous manifestations, in which the skin biopsy demonstrated multiple cutaneous microthrombi, is reported. The diagnostic and prognostic significance of this finding is discussed.
Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colorado 80045-6000.
J E
JE
Fitzpatrick
C
C
Johnson
P
P
Simon
J
J
Owenby
D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*; D013577:Syndrome; D013927:Thrombosis / Q000473:pathology*