Triazolam-induced brief episodes of secondary mania in a depressed patient.
Large doses of triazolam repeatedly induced brief episodes of mania in a depressed elderly woman. Features of organic mental disorder (delirium) were not present. Manic excitement was coincident with the duration of action of triazolam. The possible contribution of the triazolo group to changes in affective status is discussed.
Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston 02114.
J B
JB
Weilburg
G
G
Sachs
W E
WE
Falk
D000368:Aged; D001714:Bipolar Disorder / Q000139:chemically induced*; D003866:Depressive Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D014229:Triazolam / Q000009:adverse effects* / Q000627:therapeutic use
D014229:Triazolam