Does the rat have an empty stomach after an overnight fast?
Variable amounts of food have been observed in the stomachs of male rats following an overnight fast. The effects of diet and diet type on the amount of residual food left in the stomach and on fat deposition and liver weight in the male rat were investigated. The implications of these results on metabolism and pharmacokinetic studies are discussed.
Department of Biopharmaceutical Sciences and Drug Metabolism, Upjohn Limited, Sussex, United Kingdom.
P
P
Jeffrey
M
M
Burrows
A
A
Bye
D000818:Animals; D005215:Fasting; D005766:Gastrointestinal Contents; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains / Q000502:physiology*; D013270:Stomach / Q000502:physiology*