Antibiotic-associated interstitial nephritis and nephrotic syndrome.
The combination of interstitial nephritis and minimal-change nephrotic syndrome has been well described in adults receiving nonsteroidal anti-inflammatory agents. The association of interstitial nephritis and minimal-change nephrotic syndrome has recently been described in 1 adult patient receiving ampicillin and in 1 patient receiving rifampin. We describe an 8-month-old child who developed reversible interstitial nephritis and minimal-change nephrotic syndrome while taking antibiotics.
Baum
M
M
Piel
C F
CF
Goodman
J R
JR
D000658:Amoxicillin / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000009:adverse effects; D006801:Humans; D007223:Infant; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced*; D009404:Nephrotic Syndrome / Q000139:chemically induced*
D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000658:Amoxicillin