Verapamil and breast-feeding.
Concentrations of verapamil and norverapamil were measured in the plasma and breast milk of a woman receiving 120 mg verapamil three times daily. Whilst the concentrations of verapamil in breast milk averaged about 64% of those in maternal plasma no drug could be detected in the plasma of the infant. It is concluded that maternal therapy with verapamil does not pose a hazard to the suckling infant.
M R
MR
Miller
R
R
Withers
R
R
Bhamra
D W
DW
Holt
D000328:Adult; D001942:Breast Feeding; D004077:Digoxin / Q000097:blood / Q000378:metabolism; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000378:metabolism*; D014700:Verapamil / Q000009:adverse effects / Q000031:analogs & derivatives / Q000097:blood / Q000378:metabolism*
D004077:Digoxin; C016904:norverapamil; D014700:Verapamil