Trabecular (Merkel cell) carcinoma arising in the wall of an epidermal cyst.
A trabecular (Merkel cell) carcinoma arising in the wall of an epidermal cyst in a 58-year-old white male metastasized, 17 months after local excision, to an inguinal lymph node. Ultrastructural studies showed polygonal tumor cells with typical dense-core granules. Although squamous-cell carcinoma and other malignant neoplasms have been reported rarely to have arisen in epidermal cysts, a literature search failed to find a precedent for the present case.
Department of Pathology, Georgetown University School of Medicine, Washington, DC 20007.
R M
RM
Perse
R S
RS
Klappenbach
B D
BD
Ragsdale
D000230:Adenocarcinoma / Q000601:surgery / Q000648:ultrastructure*; D004814:Epidermal Cyst / Q000601:surgery / Q000648:ultrastructure*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000601:surgery / Q000648:ultrastructure*