A comparative study of different beta-whitlockite ceramics in rabbit cortical bone with regard to their biodegradation behaviour.
Different beta-whitlockite ceramic cylinders of standard size were implanted in the tibiae of rabbits to study the influence of micropores and chemistry on the biodegradation rate. The materials were evaluated by radiography and light microscopy. Surface chemistry was varied by the addition of impurities, while different applied pressures before sintering and different sintering temperatures gave rise to different micropores. Both factors influenced the biodegradation rate.
Klein
C P
CP
de Groot
K
K
Driessen
A A
AA
van der Lubbe
H B
HB
D000818:Animals; D001672:Biocompatible Materials / Q000378:metabolism*; D001673:Biodegradation, Environmental; D001842:Bone and Bones / Q000601:surgery*; D002130:Calcium Phosphates / Q000378:metabolism*; D002516:Ceramics / Q000378:metabolism*; D019736:Prostheses and Implants; D011817:Rabbits; D013499:Surface Properties
D001672:Biocompatible Materials; D002130:Calcium Phosphates; C021767:whitlockite