Mucin-producing adenoma of the thyroid gland.
The authors studied a case of mucin-producing adenoma of the thyroid gland. The tumor consisted almost entirely of signet-ring cells containing mucin, which was strongly positive with PAS, with and without diastase pre-treatment, and Alcian blue stain at pH 2.5. Immunoperoxidase staining for thyreoglobulin was clearly positive within the cytoplasm of signet-ring cells and also in the follicle material, which indicates that the tumor derived from follicular epithelium.
Brisigotti
M
M
Lorenzini
P
P
Alessi
A
A
Fabbretti
G
G
Baldoni
C
C
D000236:Adenoma / Q000378:metabolism* / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D009077:Mucins / Q000096:biosynthesis*; D010503:Periodic Acid-Schiff Reaction; D013964:Thyroid Neoplasms / Q000378:metabolism* / Q000473:pathology
D009077:Mucins