Polymicrobial early postpartum endometritis with facultative and anaerobic bacteria, genital mycoplasmas, and Chlamydia trachomatis: treatment with piperacillin or cefoxitin.
A protected, triple-lumen transcervical culture method was used to recover organisms from the endometrium. At least one facultative or one anaerobic species of bacteria was recovered from 82% of the patients, and genital mycoplasmas were recovered from 76% of the women with endometritis. Bacteria together with genital mycoplasmas were present in 61% of the women, bacteria alone were present in 20%, genital mycoplasmas alone were present in 16%, and Chlamydia trachomatis was isolated from 2% of the patients. The most common organisms included Gardnerella vaginalis, Peptococcus spp., Bacteroides spp., Staphylococcus epidermidis, group B Streptococcus, and Ureaplasma urealyticum. A randomized, double-blind regimen of either piperacillin or cefoxitin was equally successful in treating the postpartum endometritis.
Rosene
K
K
Eschenbach
D A
DA
Tompkins
L S
LS
Kenny
G E
GE
Watkins
H
H
D001437:Bacteriuria / Q000382:microbiology; D002440:Cefoxitin / Q000627:therapeutic use; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D004716:Endometritis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006801:Humans; D009174:Mycoplasma / Q000302:isolation & purification; D010878:Piperacillin / Q000627:therapeutic use; D011247:Pregnancy; D011645:Puerperal Infection / Q000188:drug therapy / Q000382:microbiology*
D002440:Cefoxitin; D010878:Piperacillin