[Primary structure and species specificity of immunopoietins].
A model involving quasicyclization of protein molecules following the stepwise reactions of limited proteolysis was developed. On the basis of the model new active sites were detected in immunoglobulins of various species as well as chemical synthesis of the sites was carried out. The new group of the substances was designated as immunopoietins. The primary structure of various species immunoglobulins was analyzed and evolutional stability of the immunopoietin structure was shown.
G I
GI
Chipens
P P
PP
Zarin'sh
L P
LP
Osis
Iu E
IuE
Antsans
D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D007128:Immunoglobulin Fragments / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D013045:Species Specificity; D013946:Thymopoietins / Q000032:analysis
D007128:Immunoglobulin Fragments; D007074:Immunoglobulin G; D013946:Thymopoietins
Pervichnaia struktura i vidovaia spetsifichnost' immunopoétinov.