[Value of mexiletine in the treatment of Thomsen-Becker myotonia].
The case of a 1 month-old boy with a severe form of Thomsen-Becker myotonia is reported. Resistance to regular antimyotonic treatment over a 3 month-period of time led to use mexiletine, an antiarrhythmic drug. This treatment was responsible for a dramatic clinical and electromyographic improvement. No adverse effect has been observed over a 16 month-period of continuous treatment.
B
B
Leheup
F
F
Himon
A
A
Morali
F
F
Brichet
M
M
Vidailhet
D004351:Drug Resistance; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008801:Mexiletine / Q000627:therapeutic use*; D009224:Myotonia Congenita / Q000188:drug therapy*; D011437:Propylamines / Q000627:therapeutic use*; D013997:Time Factors
D011437:Propylamines; D008801:Mexiletine
Intérêt de la mexilétine dans le traitement de la myotonie de Thomsen-Becker.