[Senile amyloidosis of the heart].
A morphologic study of 376 hearts from individuals who died between 75 and 98 years of age demonstrated senile amyloidosis of the heart in 307 (82%) of the cases, using the Congo red stains for polarized light studies and the thiosine red for luminescent microscopy. The frequency of cardiac amyloidosis detection increased with age, and reached 100% in those above 90. Clinico-anatomical correlations showed repolarization changes to be the most common findings (80%), followed by arrhythmia (over 50%), conductivity disorders and reduced voltage of electrocardiographic waves. Chronic heart failure was less common (about 10%). In most cases, moderately marked coronary atherosclerosis was also found at autopsy. Amyloidosis was thought to be making a more significant contribution towards myocardial lesions, as compared to atherosclerosis, in elderly people above 85 years of age.
Kukushkin
V N
VN
Moiseev
V S
VS
Polotskaia
E L
EL
Tertychnaia
G F
GF
D000367:Age Factors; D000368:Aged; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D001145:Arrhythmias, Cardiac / Q000150:complications; D009202:Cardiomyopathies / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D003327:Coronary Disease / Q000150:complications; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D009206:Myocardium / Q000473:pathology*
Senil'nyĭ amiloidoz serdtsa.