Effect of pancuronium and pethidine on heart rate and blood pressure in ventilated infants.
To investigate cardiovascular effects in 32 ventilated neonates, given either pancuronium or pethidine, computer based data were analysed for five minutes preceding and for 20 minutes after administration of the drugs. Heart rate and direct mean arterial pressure remained unchanged but arterial pressure variability decreased with each drug.
Department of Paediatrics and Neonatal Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London.
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Miall-Allen
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Whitelaw
D001794:Blood Pressure / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D008614:Meperidine / Q000494:pharmacology*; D010197:Pancuronium / Q000494:pharmacology*; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000503:physiopathology / Q000628:therapy
D008614:Meperidine; D010197:Pancuronium