[Carcinogenesis-modifying properties of aniline, carbon tetrachloride, benzene and ethanol].
Aniline and ethanol properties modifying carcinogenesis were revealed in chronic 12-month experiment with 500 females of hybrid CBAXC57Bl/6 mice. The drugs were administered with water in combination with nitrosodiethylamine. The absence of a modifying effect in groups with carbon tetrachloride and benzene is attributed to the fact that concentrations of these chemicals used in the experiment were similar to those in the environment.
Litvinov
N N
NN
Voronin
V M
VM
Kazachkov
V I
VI
D000814:Aniline Compounds / Q000633:toxicity*; D000818:Animals; D001554:Benzene / Q000633:toxicity*; D002251:Carbon Tetrachloride / Q000633:toxicity*; D004128:Dimethylnitrosamine; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000453:epidemiology; D013997:Time Factors
D000814:Aniline Compounds; D000431:Ethanol; D002251:Carbon Tetrachloride; D001554:Benzene; D004128:Dimethylnitrosamine; C023650:aniline
Izuchenie modifitsiruiuschikh kantserogenez svoĭstv anilina, chetyrekhkhloristogo ugleroda, benzola i étanola.