Sensitization to chloramphenicol; a persistent problem.
A surprisingly high incidence of chloramphenicol sensitization is reported in 8 patients with periocular or periauricular dermatitis. In 6 of them, relevance was established to the use of topical chloramphenicol. Concurrent sensitization to polymyxin B sulphate was found in 2. The findings stress the fact that chloramphenicol allergy remains a persistent problem.
van Joost
T
T
Dikland
W
W
Stolz
E
E
Prens
E
E
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000617:Aminoglycosides / Q000008:administration & dosage / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects; D002701:Chloramphenicol / Q000008:administration & dosage / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005148:Facial Dermatoses / Q000139:chemically induced; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002701:Chloramphenicol