[Complex-formation of heparin with the plasma diabetogenic factor].
Development of complexes between diabetogenic factor and heparin was shown to be responsible for effective neutralization of the factor activity. The complexes of heparin and the diabetogenic factor were obtained when various rations of the reagents were used; properties of the complexes were studied. The complexes produced, in the ratios of heparin/diabetogenic factor 1:1, 1:3, 1:6, 1:12, did not exhibit the nonenzymatic fibrinolytic activity.
B A
BA
Kudriashov
L A
LA
Liapina
D000818:Animals; D001777:Blood Coagulation; D003920:Diabetes Mellitus / Q000097:blood*; D003921:Diabetes Mellitus, Experimental / Q000097:blood; D006493:Heparin / Q000097:blood* / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D010907:Pituitary Hormones / Q000097:blood* / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D013918:Thrombin Time
C488867:DGF protein, rat; D010907:Pituitary Hormones; C010912:diabetogenic factor, human; D006493:Heparin
Kompleksobrazovanie geparina s diabetogennym faktorom plazmy krovi.