Physical partitioning as the major source of metoprolol uptake by hepatic microsomes.
Department of Biochemistry, University of Queensland, St. Lucia, Australia.
M A
MA
Bogeyevitch
E M
EM
Gillam
P E
PE
Reilly
D J
DJ
Winzor
D000818:Animals; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002927:Cimetidine / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism; D008790:Metoprolol / Q000493:pharmacokinetics*; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D051381:Rats
D002927:Cimetidine; D003577:Cytochrome P-450 Enzyme System; D008790:Metoprolol