Involvement of coagulase-negative staphylococci in toxic shock syndrome.
Coagulase-negative staphylococci that produce toxic shock syndrome toxin 1 (TSST-1) or a staphylococcal enterotoxin or both were isolated from various sources. Coagulase-negative strains that produce TSST-1 alone or with enterotoxin A were the only staphylococci isolated from seven patients with toxic shock syndrome. Two other toxic shock syndrome patients had coagulase-positive staphylococci also, but only the coagulase-negative strains produced TSST-1. Coagulase-positive and coagulase-negative strains that produced TSST-1 were isolated from two other toxic shock syndrome patients. In addition, coagulase-negative staphylococci that produced toxins were isolated from patients with other staphylococcal infections and from food implicated in a case of food poisoning.
B A
BA
Crass
M S
MS
Bergdoll
D001427:Bacterial Toxins; D003030:Coagulase / Q000378:metabolism; D004768:Enterotoxins / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D012772:Shock, Septic / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology*; D013210:Staphylococcus / Q000201:enzymology / Q000302:isolation & purification* / Q000378:metabolism; D013212:Staphylococcus epidermidis / Q000302:isolation & purification / Q000378:metabolism; D018089:Superantigens; D013630:Tampons, Surgical
D001427:Bacterial Toxins; D003030:Coagulase; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; C026066:enterotoxin A, Staphylococcal