Phenylephrine-induced reversible cataract in the mouse.
Topical 10% phenylephrine will produce lens opacities in several strains of mouse. These lens opacities resolve spontaneously within 24 hours, leaving an apparently normal eye. Phenylephrine-induced lens opacification in the mouse can be prevented by covering the eye with ointment, suggesting that the underlying mechanism is transcorneal dehydration.
Claoué
C M
CM
University of Bristol Department of Ophthalmology, Bristol Eye Hospital.
D000818:Animals; D002386:Cataract / Q000139:chemically induced*; D004195:Disease Models, Animal; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D010656:Phenylephrine
D010656:Phenylephrine