Toxicological studies on (2"R)-4'-O-tetrahydropyranyladriamycin, a new antitumor antibiotic. Its subacute toxicity in male beagle dogs.
M
M
Kurebe
M
M
Yokota
H
H
Chesterman
J E
JE
Massey
C
C
Gopinath
R
R
Heywood
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000633:toxicity*; D001774:Blood Chemical Analysis; D001835:Body Weight / Q000187:drug effects; D001853:Bone Marrow / Q000473:pathology; D002802:Cholinesterases / Q000097:blood; D004285:Dogs; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000633:toxicity; D004326:Drinking / Q000187:drug effects; D004435:Eating / Q000187:drug effects; D004562:Electrocardiography; D006403:Hematologic Tests; D008297:Male; D009929:Organ Size / Q000187:drug effects; D013737:Testis / Q000473:pathology; D014556:Urine
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin; C027260:pirarubicin; D002802:Cholinesterases