Experimental hypervitaminosis A in the rat. IX. Morphometric study of newborn young heart, whose mothers were treated with excess vitamin A.
Hypervitaminosis A induces the following changes in young ventricles of vitamin A treated mothers: ventriculum muscle fibers disorganized with minor diameter and lower nuclear volume, focal loss of transversal strias, relatively fewer mitotic figures, and interstitial fibrosis. These data were confirmed with morphometric techniques.
Department of Morphology, School of Pharmacy and Dentistry of Alfenas, Minas Gerais State, Brazil.
A M
AM
Costa
J R
JR
da Costa
R A
RA
Lopes
D000818:Animals; D000831:Animals, Newborn; D002467:Cell Nucleus / Q000648:ultrastructure; D005260:Female; D006352:Heart Ventricles / Q000473:pathology; D006986:Hypervitaminosis A / Q000473:pathology*; D008431:Maternal-Fetal Exchange; D009206:Myocardium / Q000473:pathology*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains