Effects of calcium and magnesium ions on the toxicity of cadmium to the egg of the teleost, Oryzias latipes.
The effects of calcium and magnesium ions on the toxicity of cadmium to the eggs of the freshwater teleost, Oryzias latipes, were determined. Blastulae were immersed in free medium (Ca- and Mg-free), low-Ca medium (0.25 mM Ca), high-Ca medium (1.0 mM Ca), low-Mg medium (0.25 mM Mg), and high-Mg medium (1.0 mM Mg) with cadmium chloride at 10.0 mg/liter in each solution. Almost all eggs died within 24 hr in either free medium or low-Mg medium but high-Ca medium decreased mortality remarkably: 79.9% of the eggs survived. On the other hand, there was no statistically significant difference between the cadmium content of the eggs kept in Ca-containing media and those in Mg-containing media at the corresponding molar concentrations. The present results revealed that of the two hardness constituents, calcium ions contributed to the suppression of the cadmium toxicity while magnesium ions did not.
Michibata
H
H
Sahara
S
S
Kojima
M K
MK
D000818:Animals; D002104:Cadmium / Q000032:analysis; D002105:Cadmium Poisoning / Q000378:metabolism / Q000401:mortality / Q000517:prevention & control*; D002118:Calcium / Q000494:pharmacology*; D005399:Fishes; D008274:Magnesium / Q000494:pharmacology*; D010063:Ovum / Q000032:analysis / Q000187:drug effects*
D002104:Cadmium; D008274:Magnesium; D002118:Calcium