Acute neurological toxicity of intrathecal cytosine arabinoside. A case report.
A patient developed severe neurological toxicity, with peripheral and cerebral components and hyponatraemia following one intrathecal injection of 80 mg cytosine arabinoside. The severity of his symptoms may reflect heavy prior neurotoxic chemotherapy.
Crawford
S M
SM
Rustin
G J
GJ
Bagshawe
K D
KD
D000208:Acute Disease; D000328:Adult; D001932:Brain Neoplasms / Q000188:drug therapy; D003561:Cytarabine / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000139:chemically induced*
D003561:Cytarabine