The effect of posture on diffusion into lumbar intervertebral discs.
The diffusion of small solutes into the intervertebral discs of cadaveric lumbar motion segments was measured using a radioactive tracer technique. The motion segments were wedged and loaded to simulate erect posture and flexed sitting postures. The results show that erect posture favours diffusion into the anterior half of the disc compared to the posterior half. Flexed posture, by deforming the annulus fibrosus, reverses this imbalance.
Polytechnic of Central London.
M A
MA
Adams
W C
WC
Hutton
D000293:Adolescent; D000328:Adult; D002648:Child; D004058:Diffusion; D006801:Humans; D066298:In Vitro Techniques; D007403:Intervertebral Disc / Q000378:metabolism*; D007457:Iodine Radioisotopes / Q000378:metabolism; D008159:Lumbar Vertebrae; D008433:Mathematics; D008875:Middle Aged; D008954:Models, Biological; D011187:Posture; D012979:Sodium Radioisotopes / Q000378:metabolism
D007457:Iodine Radioisotopes; D012979:Sodium Radioisotopes