2'-OH-protection by the p-nitrophenylethylsulfonyl group in oligocytidylate synthesis.
A new approach to oligoribonucleotide synthesis has been developed by use of the p-nitrophenylethylsulfonyl group as a new versatile sugar protecting group. The synthesis of 3'-5'- and 2'-5'-cydidylyl-cytidine is performed in high yield.
Fakultät für Chemie, Universität Konstanz, FRG.
M
M
Pfister
W
W
Pfleiderer
D003562:Cytidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D003568:Cytidine Monophosphate / Q000031:analogs & derivatives / Q000138:chemical synthesis*; D003597:Cytosine Nucleotides / Q000138:chemical synthesis*; D015226:Dinucleoside Phosphates; D007202:Indicators and Reagents; D009578:Nitrobenzenes; D009843:Oligoribonucleotides; D013450:Sulfones
D003597:Cytosine Nucleotides; D015226:Dinucleoside Phosphates; D007202:Indicators and Reagents; D009578:Nitrobenzenes; D009843:Oligoribonucleotides; D013450:Sulfones; C015101:cytidylyl-(3'-5')-cytidine; D003562:Cytidine; D003568:Cytidine Monophosphate