Lymphocytopenia in high cancer risk population: evidence in automobile pattern makers.
A total of 1454 automobile pattern makers were studied to determine the degree of lymphocyte reduction. These occupational workers have been known to be at high risk for colorectal cancer. As a group, pattern makers had significantly lower lymphocyte counts than the comparison group. The proportion of lymphocytopenia (less than 1500/mm3) in pattern makers was 26.2% as compared with 5.6% in the comparison group. Continuous monitoring of lymphocyte reduction in pattern makers may be worthwhile to evaluate whether these workers face a high risk for deficiency in lymphocytes in association with their risk for high rates of colorectal cancer.
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D001336:Automobiles; D006801:Humans; D008231:Lymphopenia / Q000453:epidemiology*; D009784:Occupational Diseases / Q000453:epidemiology*; D012306:Risk