Systemic lupus erythematosus with nephritis in children. A report of 6 cases.
Six children with systemic lupus erythematosus treated over the last 10 years are described. There are 3 boys and 3 girls and their ages at presentation ranged from 9.25 to 15 years; follow-up ranges from 11 months to 12 years. The modalities of treatment, methods of follow-up, and regular assessment of lupus activity are discussed with a brief review of the relevant literature. One patient has progressed to end-stage renal failure and is awaiting renal transplantation. Of the others, 2 have mild renal impairment and 3 have normal renal function. We believe that an aggressive therapeutic approach with meticulous follow-up can improve the outlook in children with this condition.
Ransome
O J
OJ
Thomson
P D
PD
D000293:Adolescent; D002648:Child; D005260:Female; D005921:Glomerulonephritis / Q000150:complications*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy*; D008297:Male; D009393:Nephritis / Q000150:complications*