Further studies on the standardization of neonatal bilirubin.
Certain problems in the standardization of direct-reading instruments (bilirubinometers) were investigated. It was shown that the combination of wavelength setting and choice of pH is very important with respect to the standard to be used. It is emphasized that in fact there is no synthetic bilirubin standard which can be used as primary standard. Reasons are given why the only pragmentic solution proved to be a pool of neonatal serum.
Blijenberg
B G
BG
Department of Clinical Chemistry, Academic Hospital Rotterdam-Dijkzigt, The Netherlands.
Roetering
H A
HA
de Vos
A
A
Leijnse
B
B
D000328:Adult; D000818:Animals; D001663:Bilirubin / Q000032:analysis*; D002417:Cattle; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D012015:Reference Standards; D013053:Spectrophotometry
D001663:Bilirubin