Clomipramine, tryptophan and lithium in combination for resistant endogenous depression: seven case studies.
Seven patients suffering from severe endogenous depression who had proven resistant to lengthy trials of treatment with tricyclic and other antidepressants are described. Their successful treatment with a combination of clomipramine, L-tryptophan and lithium is discussed in the context of other strategies for the treatment of resistant depression.
Hale
A S
AS
Brook General Hospital, London.
Procter
A W
AW
Bridges
P K
PK
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D002908:Chronic Disease; D002997:Clomipramine / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D014364:Tryptophan / Q000627:therapeutic use*
D000929:Antidepressive Agents, Tricyclic; D014364:Tryptophan; D008094:Lithium; D002997:Clomipramine