Double IgA bands in serum from a patient with lymphoplasmacytoid leukemia with hairy-cell morphology.
We present a case of plasmacytoid lymphocytic leukemia with hairy-cell-like cytoplasmic projections and separate monomeric and polymeric IgA(lambda) serum bands confirmed by immunofixation. After a prolonged initial good response to chemotherapy, the patient had recurrent disease with increased plasmacytoid blastic feature and died. The relationship of this case to B-cell proliferative disorders is discussed.
Loo
S Y
SY
Department of Pathology, Kaiser Foundation Hospital, Honolulu, HI 96819.
Bhagavan
N V
NV
Scottolini
A G
AG
D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D007943:Leukemia, Hairy Cell / Q000276:immunology* / Q000473:pathology; D007945:Leukemia, Lymphoid / Q000276:immunology* / Q000473:pathology; D007952:Leukemia, Plasma Cell / Q000276:immunology* / Q000473:pathology; D008297:Male; D008875:Middle Aged
D007070:Immunoglobulin A