Disseminated rhinosporidiosis.
This paper reports a case of rhinosporidiosis which presented with widespread subcutaneous nodular lesions which failed to respond to surgical excision or to intravenous amphotericin B. Lesions in sites away from the nasal cavities are usually believed to be brought about by direct infection or by fingerborne autoinoculation. In this case, haematogenous dissemination was shown by the presence of sporangia within the lumen of a blood vessel. Systemic rhinosporidiosis is an extremely rare condition.
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D001808:Blood Vessels / Q000382:microbiology / Q000473:pathology; D003881:Dermatomycoses / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000382:microbiology / Q000473:pathology; D012227:Rhinosporidiosis / Q000382:microbiology / Q000473:pathology*; D012846:Singapore; D013172:Spores, Fungal / Q000648:ultrastructure