Synthesis and antibacterial activity of C-3' isothiazolyl and related cephalosporins.
The synthesis of C-3' isothiazolyl and related cephalosporins is presented. The compounds exhibit activity against a variety of Gram-positive and Gram-negative organisms.
Skotnicki
J S
JS
Strike
D P
DP
D002511:Cephalosporins / Q000138:chemical synthesis* / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D002511:Cephalosporins; D013844:Thiazoles