Episodic secretion of met-enkephalin immunoreactive material in human plasma and CSF.
Plasma and CSF met-enkephalin immunoreactive material (ME-IR) concentrations were measured in 5 subjects at different hours of the day. Within the 24 hrs CSF ME-IR concentrations ranged in the same patient from 20 to 5000 pg/ml. Plasma ME-IR concentrations presented a circadian rhythm with lower values between 4:00 and 8:00 p.m.
Govoni
S
S
Salar
G
G
Colombo
F
F
Pasinetti
G
G
Trabucchi
M
M
Mingrino
S
S
D000328:Adult; D000368:Aged; D004744:Enkephalin, Methionine / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D013997:Time Factors
D004744:Enkephalin, Methionine