Massive propranolol overdose poorly responsive to pharmacologic therapy: use of the intra-aortic balloon pump.
Reported is the case of a 17-year-old woman who experienced full cardiac arrest less than one hour after ingesting 8 g of propranolol. More than two hours of CPR were required because she did not respond to glucagon or high doses of beta and alpha agonists. An intra-aortic balloon pump was used for hemodynamic support of drug-induced cardiogenic shock when pulses returned. She experienced complete recovery without sequelae.
Lane
A S
AS
Department of Internal Medicine, Newton-Wellesley Hospital, Newton Lower Falls, Massachusetts 02162.
Woodward
A C
AC
Goldman
M R
MR
D000293:Adolescent; D004554:Electric Countershock; D005260:Female; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D011433:Propranolol / Q000506:poisoning*; D012151:Resuscitation; D012640:Seizures / Q000139:chemically induced / Q000188:drug therapy; D012770:Shock, Cardiogenic / Q000139:chemically induced / Q000628:therapy; D013610:Tachycardia / Q000139:chemically induced / Q000188:drug therapy
D011433:Propranolol