Ferromagnetic particles as contrast agents for magnetic resonance imaging of liver and spleen.
Particles of magnetite, Fe3O4, accumulate preferentially in the liver and spleen after intravenous injection. Their magnetic fields drastically decrease echo intensities in spin-echo proton magnetic resonance imaging sequences, as demonstrated by experiments on dogs injected with 10 mg/kg of 0.05-micron particles.
M H
MH
Mendonca Dias
P C
PC
Lauterbur
D000818:Animals; D003287:Contrast Media; D004285:Dogs; D052203:Ferrosoferric Oxide; D007501:Iron; D008099:Liver / Q000033:anatomy & histology*; D009682:Magnetic Resonance Spectroscopy; D010087:Oxides; D013154:Spleen / Q000033:anatomy & histology*
D003287:Contrast Media; D010087:Oxides; D007501:Iron; D052203:Ferrosoferric Oxide