Upper gastrointestinal endoscopy in normal asymptomatic volunteers.
In a prospective study, 355 healthy, asymptomatic, male volunteers, 18 to 45 years of age, were screened by esophagogastroduodenoscopy before admission to clinical trials. One hundred thirty-four volunteers (38%) showed abnormal endoscopic findings. Some volunteers had more than one site of involvement or more than one grade of lesion in each anatomic location. In 49 (14%) of these subjects the esophagus was a site of involvement, while in 86 (24%) the stomach was involved, and in 71 (20%) the duodenum was involved. The point prevalences in these asymptomatic subjects were 8.5% for erosive esophagitis, 12% for erosive gastritis, 10% for erosive duodenitis, 2% for gastric ulcer, and 2% for duodenal ulcer.
Akdamar
K
K
Ertan
A
A
Agrawal
N M
NM
McMahon
F G
FG
Ryan
J
J
D000293:Adolescent; D000328:Adult; D004381:Duodenal Ulcer / Q000175:diagnosis; D004382:Duodenitis / Q000175:diagnosis; D004384:Duodenoscopy; D004724:Endoscopy; D004941:Esophagitis / Q000175:diagnosis; D004945:Esophagoscopy; D005756:Gastritis / Q000175:diagnosis; D005767:Gastrointestinal Diseases / Q000175:diagnosis*; D005773:Gastroscopy; D006801:Humans; D008875:Middle Aged; D013276:Stomach Ulcer / Q000175:diagnosis