[Peripheral neuropathy in severe mixed cryoglobulinemia syndrome].
A syndrome of polyneuropathy and cryoglobinemia is reported in a 76-year-old woman. Nerve biopsy showed severe demyelination and vascular involvement was demonstrated in a muscle biopsy. Peripheral neuropathy is discussed in the context of the Gougerot-Sjögren syndrome, associated with cryoglobins in the blood. Prompt treatment of this disease should be initiated and consists mainly of plasmapheresis.
Service de neurologie, VASTEL, Centre hospitalier regional et universitaire de Caen, France.
J P
JP
Thenint
M J
MJ
Penniello
F
F
Chapon
F
F
Viader
A
A
Beaudoin
P
P
Morin
D000368:Aged; D001369:Axons / Q000648:ultrastructure; D003449:Cryoglobulinemia / Q000473:pathology*; D003711:Demyelinating Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009138:Musculocutaneous Nerve / Q000473:pathology; D009186:Myelin Sheath / Q000648:ultrastructure; D009410:Nerve Degeneration; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D011115:Polyneuropathies / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000473:pathology*
Neuropathie Périphérique Cryoglobulinémie Mixte Syndrome Sec.