The regulation of the biologically available fractions of oestradiol and testosterone in plasma.
The albumin bound fractions of oestradiol and testosterone have been measured in samples of plasma obtained over a 24 h period from women with breast cancer or polycystic ovarian disease and from pre- and postmenopausal control subjects and related to plasma levels of free fatty acids. For most subjects changes in the fraction of oestradiol bound to albumin were related to changes in plasma levels of free fatty acids. A significant decrease in the albumin bound testosterone fraction during the night was associated with increased plasma levels of cortisol.
M J
MJ
Reed
R W
RW
Cheng
P A
PA
Beranek
J D
JD
Few
S
S
Franks
M W
MW
Ghilchik
V H
VH
James
D001682:Biological Availability; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D011085:Polycystic Ovary Syndrome / Q000097:blood; D011485:Protein Binding; D013739:Testosterone / Q000097:blood*
D013739:Testosterone; D004958:Estradiol