Pneumococcal antigens in sputa: ELISA for the detection of pneumococcal C-polysaccharide in sputa from pneumonia patients.
An improved ELISA, the LKB UltroBact Pneumococcus Kit detecting pneumococcal C-polysaccharide, has been tested. Sputum samples from 72 patients with community acquired pneumonia were included in the study. The sensitivity obtained was 96.1% and the specificity 92.6%. This ELISA might offer a useful diagnostic method in major clinical microbiologic laboratories for demonstrating Streptococcus pneumonia in sputa from patients with pneumonia.
Department of Infectious Diseases, Roslagstulls Hospital, Karolinska Institute, Stockholm, Sweden.
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Krook
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Holmberg
D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis / Q000276:immunology*; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D013183:Sputum / Q000276:immunology*; D013296:Streptococcus pneumoniae / Q000276:immunology*
D011135:Polysaccharides, Bacterial