Determination of 2,3-dibromopropanol in air.
One of the starting materials for the preparation of TRIS-BP (tris-2,3-dibromopropanol phosphate), which is used in the treatment of fabrics and various materials to make them nonflammable, is 2,3-dibromopropanol. Because of the reported toxic nature of its parent phosphate compound, 2,3-dibromopropanol recently has been used by itself as a fire retardant. The manufacture and use of 2,3-dibromopropanol as a fire retardant, however, have been a matter of great concern in the workplace because of its mutagenic, carcinogenic and nephrotoxic nature. A sensitive air sampling and analytical method has been developed as part of a complete field survey protocol. This paper describes the development of an air sampling and gas-liquid chromatographic analysis procedure for 2,3-dibromopropanol. The detection limit for the method is 5 microg per sample and the relative standard deviation for the method is 5%.
U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Cincinnati, OH 45226.
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Choudhary
D000433:1-Propanol / Q000032:analysis; D000327:Adsorption; D000395:Air Pollutants, Occupational / Q000032:analysis*; D002849:Chromatography, Gas; D005069:Evaluation Studies as Topic; D005411:Flame Retardants / Q000032:analysis*; D020005:Propanols; D011786:Quality Control
D000395:Air Pollutants, Occupational; D005411:Flame Retardants; D020005:Propanols; D000433:1-Propanol; C016369:2,3-dibromopropanol