Rheographic indications for reduced cerebral vasoconstriction after oral magnesium medication in tetanic patients, a double-blind, placebo-controlled trial.
Volume and tonus oscillations of cerebral blood vessels are measurable with rheoencephalography. A lowered amplitude under resting conditions and an increased reactivity after hyperventilation (with pronounced and prolonged vasoconstriction) was found in tetanic patients, 360 mg Mg/day (as magnesium citrate tablets) was administered in 17 tetanic patients (A) and a placebo in 18 patients (B) in a double-blind, placebo-controlled trial. After 4 weeks the hyperventilation-induced vasoconstriction was reduced significantly within group A compared to group B.
Fehlinger
R
R
Mielke
U
U
Fauk
D
D
Seidel
K
K
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000098:blood supply*; D004311:Double-Blind Method; D004341:Drug Evaluation; D004573:Electrolytes / Q000097:blood; D005260:Female; D006801:Humans; D008274:Magnesium / Q000097:blood / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010992:Plethysmography, Impedance; D013746:Tetany / Q000097:blood / Q000188:drug therapy*; D014661:Vasoconstriction / Q000187:drug effects*
D004573:Electrolytes; D008274:Magnesium