Caffeine-induced cerebral blood flow changes in schizophrenia.
Cerebral blood flow (CBF) measurements and mental status examinations were performed before and 30 min after oral administration of 250 mg of caffeine or a placebo given under double-blind conditions, in two groups of patients with schizophrenia. Caffeine produced significant CBF reductions but no changes in the patient's clinical condition.
Mathew
R J
RJ
Wilson
W H
WH
Tant
S
S
D000328:Adult; D002110:Caffeine / Q000494:pharmacology*; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D012039:Regional Blood Flow / Q000187:drug effects; D012559:Schizophrenia / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D014661:Vasoconstriction / Q000187:drug effects
D002110:Caffeine