The significance of female sex steroids on the vascular permeability of the traumatised uterine serosa of rats.
Using experiments with conjugated hormones, and their influence on vascular permeability assessed by the colloidal carbon technique, we have investigated the effect of female sex steroids on the microcirculation of the uterine horn of virgin rats. We found that oestrogen inhibited vascular permeability in inflammatory conditions. Progesterone increased vascular permeability.
Laboratory of Experimental Pathology, University of São Paulo, Brazil.
M A
MA
Gouveia
H W
HW
Halbe
N
N
Schutze Filho
D000818:Animals; D002199:Capillary Permeability; D004716:Endometritis / Q000503:physiopathology*; D004967:Estrogens / Q000502:physiology*; D005260:Female; D008866:Microsurgery; D011183:Postoperative Complications / Q000503:physiopathology; D011374:Progesterone / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D000267:Tissue Adhesions; D014599:Uterus / Q000098:blood supply* / Q000601:surgery; D014945:Wound Healing
D004967:Estrogens; D011374:Progesterone