[The immunomodulator thymalin in the experimental chemotherapy of tumors].
Experiments on inbred and noninbred mice showed thymalin to potentiate the therapeutic effect of cytostatic drugs. Thymalin treatment was followed by inhibition of tumor growth and dissemination, increase in the animal's life span and amelioration of antitumor drug-induced immunodepression.
Amosova
E N
EN
Iaremenko
K V
KV
Cherdyntseva
N V
NV
Nikolin
V P
VP
Ogreba
V I
VI
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D051379:Mice; D008815:Mice, Inbred Strains; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000276:immunology / Q000628:therapy*; D009504:Neutrophils / Q000276:immunology; D013951:Thymus Hormones / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents; D013951:Thymus Hormones; C032805:thymalin; D003520:Cyclophosphamide
Immunomoduliator timalin v éksperimental'noĭ khimioterapii opukholeĭ.