[Clinical and experimental studies on the FHR sinusoidal pattern].
Fetal heart rate records of 22 patients were analysed with a computerized digitizer. A sinusoidal pattern (SP), selected by using Maeda's tentative criteria, was observed in 8 patients, and a wavy pattern (WP) in 14 patients. There were no significant differences between SP and WP cases in the mean amplitudes and frequencies, but in SP cases both coefficients of variation of amplitude and frequency were respectively smaller than those in WP. The sinusoidal pattern index (SPI) was over 22 in SP and below 21 in WP. Therefore, the SPI was a useful parameter in the detection of SP. SP cases showed such poor prognosis as intrauterine fetal death, neonatal death, and fetal distress in labor. Most cases of SP and WP observed in the antepartum period showed abnormal courses in labor, but all cases observed during labor were normal. The heart rate patterns of adult rabbits were investigated in an experimentally induced hypoxic state in 3 cases, acute anemic state in 7 cases, and hypoxia combined with anemic state in 7 cases. SP was observed in 5 cases in the third group, and the blood pressure was about 20 mmHg during SP without synchronous change. It was suggested that a combination of anemic and hypoxic states was closely related to the sinusoidal heart rate pattern, and that it was induced by the dysfunction of the central nervous system in a hypotensive condition.
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Hidaka
D000740:Anemia / Q000175:diagnosis; D000818:Animals; D005260:Female; D005313:Fetal Death / Q000175:diagnosis; D005315:Fetal Diseases / Q000175:diagnosis*; D005316:Fetal Distress / Q000175:diagnosis; D005318:Fetal Heart / Q000502:physiology*; D005311:Fetal Hypoxia / Q000175:diagnosis; D005323:Fetal Monitoring; D006339:Heart Rate; D006801:Humans; D007743:Labor, Obstetric; D008838:Microcomputers; D011247:Pregnancy; D011817:Rabbits