Glutathione-mediated activation of anticancer platinum(IV) complexes.
Eastman
A
A
Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha 68105.
D000818:Animals; D002945:Cisplatin / Q000378:metabolism / Q000494:pharmacology; D004247:DNA / Q000378:metabolism*; D004351:Drug Resistance; D005978:Glutathione / Q000494:pharmacology*; D007939:Leukemia L1210; D051379:Mice; D009944:Organoplatinum Compounds / Q000378:metabolism* / Q000494:pharmacology; D010084:Oxidation-Reduction; D014407:Tumor Cells, Cultured
D009944:Organoplatinum Compounds; C024236:1,2-diaminocyclohexyl platinum sulfate; D004247:DNA; D005978:Glutathione; D002945:Cisplatin; C049777:ormaplatin