Human placental and intestinal alkaline phosphatase genes map to 2q34-q37.
The alkaline phosphatases comprise a multigene enzyme family that hydolyze phosphate esters and are widely distributed in nature. Three main classes have been isolated from humans, the placental, intestinal, and liver/bone/kidney forms. We have mapped the placental and intestinal alkaline phosphatase genes to 2q34-q37 by using chromosomal in situ hybridization and a somatic-cell hybrid panel.
Griffin
C A
CA
Department of Pediatrics, Children's Hospital of Philadelphia, PA 19104.
Smith
M
M
Henthorn
P S
PS
Harris
H
H
Weiss
M J
MJ
Raducha
M
M
Emanuel
B S
BS
D000469:Alkaline Phosphatase / Q000235:genetics*; D000818:Animals; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D004247:DNA / Q000235:genetics; D005260:Female; D006801:Humans; D006822:Hybrid Cells; D007422:Intestines / Q000201:enzymology*; D005810:Multigene Family; D009693:Nucleic Acid Hybridization; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D051381:Rats
D004247:DNA; D000469:Alkaline Phosphatase