Treatment of hairy cell leukaemia with recombinant alpha-interferon.
Of 10 patients with hairy cell leukaemia treated with 3 mU recombinant alpha-interferon daily, 9 showed clinical haematological response--including 2 patients who achieved complete remission. Unmaintained responses have continued for as long as 18+ months after completion of therapy. There was no significant toxicity associated with this treatment schedule.
Bezwoda
W R
WR
Department of Medicine, University of the Witwatersrand, Johannesburg.
Hesdorffer
C S
CS
Dansey
R D
RD
Lewis
D
D
D000328:Adult; D001772:Blood Cell Count; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D007943:Leukemia, Hairy Cell / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins / Q000627:therapeutic use; D013156:Splenectomy; D013997:Time Factors
D007370:Interferon Type I; D011994:Recombinant Proteins