Phenylephrine-induced reversible cataract in the mouse.
Topical 10% phenylephrine will produce lens opacities in several strains of mouse. These lens opacities resolve spontaneously within 24 hours, leaving an apparently normal eye. Phenylephrine-induced lens opacification in the mouse can be prevented by covering the eye with ointment, suggesting that the underlying mechanism is transcorneal dehydration.
University of Bristol Department of Ophthalmology, Bristol Eye Hospital.
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Claoué
D000818:Animals; D002386:Cataract / Q000139:chemically induced*; D004195:Disease Models, Animal; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008815:Mice, Inbred Strains; D010656:Phenylephrine
D010656:Phenylephrine