Ultraviolet light absorption in intraocular lenses.
Implantation of ultraviolet (UV) light-absorbing intraocular lenses and the manufacturers developing these lenses has significantly increased over the past few years. In this paper, the need for filtration of UV light by intraocular lens implants is briefly examined and various new product development aspects of a UV-absorbing IOL are discussed. Two general approaches, additive and chemical bonding, to incorporating a UV-absorbing chromophore into polymethylmethacrylate lens material are described. Different UV-absorbing compounds that are being used in implants and the mechanism by which they absorb light and its dissipation is discussed. The extent of preclinical testing required to establish the biocompatibility, stability, and overall safety of new materials is summarized. Finally, a relative comparison of the extent of UV absorption by various commercially available UV intraocular lenses is presented.
Lindstrom
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RL
Doddi
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D005374:Filtration; D006801:Humans; D007910:Lenses, Intraocular; D008269:Macular Edema / Q000517:prevention & control; D010777:Photochemistry; D011474:Prosthesis Design; D014466:Ultraviolet Rays / Q000009:adverse effects