Radiation therapy as adjuvant treatment after radical prostatectomy: patient tolerance and preliminary results.
For the last 7 years we administered therapeutic doses of radiation therapy as adjuvant treatment after radical prostatectomy in 45 patients at high risk for recurrence, that is patients with pathological stage C (seminal vesicle invasion) or stage D1a (microscopic involvement of the resected pelvic lymph nodes) disease. All of the patients have been followed for at least 2 years. Short-term and long-term complications were minimal; only 2 patients had significant sequelae that were managed satisfactorily. There has been no local recurrence after mean followups of 62 and 48 months for patients with stages C and D1a disease, respectively. The actuarial 5-year survival rate free of disease was 79 per cent for patients with stage C and 72 per cent with stage D1a cancer.
Lange
P H
PH
Moon
T D
TD
Narayan
P
P
Medini
E
E
D002277:Carcinoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery