[Conjugates of amino acids with glucosamine isolated from the plasma of rats with Guerin carcinoma].
The conjugate of amino acids and glucosamine (glycamine) was purified to homogeneity from blood plasma of rats with Guerin carcinoma. The NH2-groups of amino acids in the glycamine are free. Amino acids are linked to glucosamine via carboxyl groups. 8 amino acids residues were identified in the glycamine molecule (Glu-2, Ser-2, Gly-3, Lys-1). Spatial atomic-molecular model of the glycamine molecule was developed. Two glucosamine molecules are linked to diaminosaccharide via (1-4)-bond, 8 amino acid molecules are linked to diaminosaccharide via 6 ester and 2 pseudopeptide bonds.
G V
GV
Glinskiĭ
V B
VB
Vinnitskiĭ
D000596:Amino Acids / Q000097:blood*; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005260:Female; D005944:Glucosamine / Q000097:blood*; D006001:Glycoconjugates / Q000097:blood; D008297:Male; D008958:Models, Molecular; D008970:Molecular Weight; D009374:Neoplasms, Experimental / Q000097:blood*; D051381:Rats
D000596:Amino Acids; D006001:Glycoconjugates; D005944:Glucosamine
Issledovanie kon''iugata aminokislot s gliukozaminom, vydelennogo iz plazmy krovi krys s kartsinomoĭ Gerena.