[Dependence of the migration activity of blood granulocytes from healthy donors and from bronchial asthma patients on the presence of cellular mediators].
The migration activity of granulocytes in human blood has been shown to depend both on the locomotor properties of these cells and on the presence of cell mediators secreted by blood mononuclears and by granulocytes themselves. Granulocytes in the blood of patients with the atopic form of bronchial asthma differ from granulocytes in healthy donors by sharply decreased spontaneous migration activity. Granulocytes and mononuclears in the blood of patients with the atopic form of bronchial asthma differ from the corresponding cells of donor blood in the activity of cell mediators secreted by them and influencing the migration of granulocytes in the donors.
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Totolian
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Freĭdlin
D001249:Asthma / Q000276:immunology*; D002465:Cell Movement; D002478:Cells, Cultured; D006098:Granulocytes / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007958:Leukocyte Count; D009000:Monocytes / Q000276:immunology; D013997:Time Factors
Zavisimost' migratsionnoĭ aktivnosti granulotsitov krovi zdorovykh donorov i bol'nykh bronkhial'noĭ astmoĭ ot prisutstvii kletochnykh mediatorov.