[Stimulation of egg development in female nematodes by beta-diethylaminoisobutyronitrile].
The biological activity of a new organic compound beta-diethylaminoisobuthironitrile was determined. A new phenomenon for nematodes of open-type larval development (Strongyloid) was found. Alive females of nematodes belonging to the genera Trichostrongylus, Ostertagia, Bunostomum and Haemonchus were treated with 5 volumes-% mixture of the compound with water. The development of eggs of these nematodes in the mother body and output of larvae in female were observed. The larvae lead an active mode of life, feed and are capable of developing. Optimal exposure of females in solution is 4 hours for Haemonchus and Trichostrongylus, 2 hours for Bunostomum, and 3 hours for Ostertagia. Stimulation of egg development in nematodes of semiclose and semi-open types was not observed.
Sadykhov
I A
IA
Akhmedov
R M
RM
Khanbekova
E M
EM
D000818:Animals; D005260:Female; D007422:Intestines / Q000469:parasitology; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D009348:Nematoda / Q000187:drug effects* / Q000254:growth & development; D009570:Nitriles / Q000494:pharmacology*; D010063:Ovum / Q000187:drug effects* / Q000254:growth & development; D012756:Sheep / Q000469:parasitology; D013268:Stimulation, Chemical
D009570:Nitriles; C048548:beta-(diethylamino)isobutyronitrile
Stimulirovanie razvitiia iaits vnutri samok nematod deĭstviem beta-diétilaminoizobutironitrila.