A new promising treatment in systemic sclerosis: 5-fluorouracil.
Twelve patients with systemic sclerosis according to American Rheumatism Association criteria were treated with intravenous 5-fluorouracil. Significant subjective and objective improvement occurred initially in the skin and subsequently in the involved viscera and vasculature. These preliminary results suggest that 5-fluorouracil may be an effective treatment for systemic sclerosis.
Casas
J A
JA
Department of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
Subauste
C P
CP
Alarcón
G S
GS
D000328:Adult; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000188:drug therapy*
D005472:Fluorouracil