Spherocytosis associated with anaplasmosis in two cows.
Spherocytes were detected on blood smears of 2 Angus cows. The RBC from both cows had increased fragility in hypotonic saline solution, supporting the presence of spherocytes. Other laboratory tests revealed a macrocytic, regenerative anemia with anisocytosis, polychromasia, basophilic stippling, Howell-Jolly bodies, nucleated RBC, and Anaplasma marginale organisms. A complement-fixation test was positive for anaplasmosis in cow 1 and a direct Coombs' test was positive for immunoglobulin G in both cows.
Swenson
C
C
Jacobs
R
R
D000712:Anaplasmosis / Q000175:diagnosis / Q000662:veterinary*; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000662:veterinary*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis*; D003298:Coombs Test; D004913:Erythrocytes, Abnormal; D005260:Female; D013102:Spherocytes