Regeneration of an enchondroma defect under the influence of an implant of human bone morphogenetic protein.
A 29-year-old woman with an enchondroma that was expanding and eroding the palmar cortex of the middle phalanx was successfully treated by curettage and implantation of bone morphogenetic protein. The metaphysis and cortex were repaired by lamellar bone within 2 months. The medulla was completely filled with trabecular bone by 9 months. The full range of motion and normal functions of finger and hand joints were restored, and there was no recurrence or abnormalities at follow-up visits 2 1/2 years after the operation.
Urist
M R
MR
Kovacs
S
S
Yates
K A
KA
D000328:Adult; D019485:Bone Morphogenetic Proteins; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D001861:Bone Regeneration; D002812:Chondroma / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005385:Fingers / Q000000981:diagnostic imaging; D006801:Humans; D011506:Proteins / Q000627:therapeutic use*; D011859:Radiography
D019485:Bone Morphogenetic Proteins; D011506:Proteins