Free fatty acids: a possible regulator of the available oestradiol fractions in plasma.
Consumption of dietary fats has been linked to the high incidence of breast cancer found in Western women. In vitro studies we have carried out show that unsaturated free fatty acids can increase the biologically available oestradiol fractions in plasma. It is possible therefore that the increased risk for breast cancer associated with a diet high in fats may be related to an elevation in the biologically available oestradiol fractions in plasma.
Reed
M J
MJ
Beranek
P A
PA
Cheng
R W
RW
James
V H
VH
D004041:Dietary Fats / Q000494:pharmacology; D004958:Estradiol / Q000097:blood*; D005230:Fatty Acids, Nonesterified / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008593:Menopause
D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D004958:Estradiol