[Structural characteristics of a population of antigenic variants of the influenza A(H3N2) virus].
The data have been obtained indicating that clone distribution by the antigen avidity in the population of influenza A (H3N2) virus corresponds to normal distribution. The degree of avidity of individual strains is determined by the predominant content of clones with high or low avidity. Virus purification by ultracentrifugation in sucrose density gradient results in increasing the avidity of the preparation as compared with the original allantoic cultures. Defective virions may differ in avidity from intact viral particles of the same strain and in this way affect the "total" avidity of a virus preparation.
S V
SV
Kolotvinov
I P
IP
Manova
S S
SS
Galitarov
V P
VP
Sukhinin
D000915:Antibody Affinity; D000940:Antigenic Variation; D000956:Antigens, Viral / Q000032:analysis*; D003001:Cloning, Molecular / Q000379:methods; D003673:Defective Viruses / Q000276:immunology / Q000648:ultrastructure; D006385:Hemagglutination Inhibition Tests / Q000379:methods; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus / Q000276:immunology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D014771:Virion / Q000276:immunology / Q000648:ultrastructure
D000956:Antigens, Viral
Osobennosti struktury populiatsii antigennykh variantov virusa grippa A(H3N2).