Severe obstetric complications after aggressive treatment of Asherman syndrome.
Thirty-three cases of Asherman syndrome from Yale-New Haven Hospital are presented. Restoration of menses occurred in 91% of patients with pregnancy resulting in 79% of all treated patients. Spontaneous abortion occurred in only one patient (4%), whereas viable pregnancies resulted 96% of the time. Severe obstetric complications excluding premature labor occurred in three cases (12%) and included placenta increta, uterine sacculation, and a paper-thin uterine fundus (ie, uterine dehiscence). These cases are discussed to reinforce considering treated patients with Asherman syndrome to be a high-risk obstetric population, and to counsel and manage these patients accordingly.
Friedman
A
A
DeFazio
J
J
DeCherney
A
A
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008599:Menstruation Disturbances / Q000628:therapy*; D007752:Obstetric Labor, Premature / Q000209:etiology; D010921:Placenta Accreta / Q000209:etiology; D010922:Placenta Diseases / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology* / Q000628:therapy; D013577:Syndrome; D014591:Uterine Diseases / Q000209:etiology*