Drug treatment of changes in platelet-vessel wall interactions in burned rats.
The interaction between blood platelets and the walls of blood vessels is changed after burn injury to rats and guinea-pigs. Treatment of burned experimental animals with heparin, nicotinic acid, thrental, phytin, glutamic acid and alpha-tocopherol inhibited the increase in platelet-vascular wall interaction, improved the microcirculation in mesenteric vessels and increased the endurance of the animals to physical stress.
Baluda
V P
VP
Lukhoyanova
T I
TI
Kozelskaya
L V
LV
Zyablitsky
V M
VM
Iashvili
B P
BP
Vakulenko
A D
AD
Staroselskaya
A N
AN
D000818:Animals; D001792:Blood Platelets / Q000503:physiopathology*; D001808:Blood Vessels / Q000473:pathology / Q000503:physiopathology*; D002056:Burns / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D008315:Malondialdehyde; D008642:Mesenteric Veins / Q000473:pathology; D010974:Platelet Aggregation; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D008315:Malondialdehyde