Confirmation of a prognostic index in primary breast cancer.
A prognostic index, previously derived in a group of 387 patients with primary breast cancer, has been recalculated for the same patients with over 5 years further follow-up and shown to be unchanged. The prognostic index has also been applied prospectively to a further group of 320 patients and shown to be similarly effective in identifying patients with either a very good or a very poor prognosis. It has been verified that the index applies to patients with primary breast cancer. Patients have now been divided into 5 prognostic groups, predicting 11% of patients with an almost normal survival and a further 10% with a very poor prognosis. The index is used to stratify patients to study the effects of treatment regimes within groups of similar patients.
City Hospital, Nottingham, UK.
J H
JH
Todd
C
C
Dowle
M R
MR
Williams
C W
CW
Elston
I O
IO
Ellis
C P
CP
Hinton
R W
RW
Blamey
J L
JL
Haybittle
D001943:Breast Neoplasms / Q000032:analysis / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008593:Menopause; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis; D013997:Time Factors
D011960:Receptors, Estrogen