Synthesis and separation of diastereoisomers of 5'-O-(4,4'-dimethoxytrimethylphenyl)dithymidyl-(3,5')-4,4' -dimethoxytriphenylmethanephosphonate.
"In solution" synthesis and separation of diastereoisomers of 5'-O-(4,4'-dimethoxytriphenylmethyl)dithymidyl (3',5') 4,4'-dimethoxytriphenylmethanephosphonate (DMTTDMTT) is described. One of diastereoisomers was successfully crystallized and characterized by means of HPLC.
Department of Bio-organic Chemistry, Polish Academy of Sciences, Lodz.
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Wilk
W J
WJ
Stec
D002851:Chromatography, High Pressure Liquid; D007202:Indicators and Reagents; D013237:Stereoisomerism; D013942:Thymine Nucleotides / Q000138:chemical synthesis* / Q000302:isolation & purification
D007202:Indicators and Reagents; D013942:Thymine Nucleotides; C054405:5'-O-(4,4'-dimethoxytriphenylmethyl)dithymidyl (3',5')-4,4'-dimethoxytriphenylmethanephosphonate