Effect of glutaurine on sleep-wakefulness cycle and aggressive behaviour in the cat.
The effects of glutaurine (gamma-L-glutamyl taurine, Litoralon, Chinoin, Budapest) on the aggressive behaviour and sleep-wakefulness cycle were studied in freely moving cats. Glutaurine, even in doses as low as 0.1 microgram/kg, was found significantly to shorten the latency of the rat-killing reaction elicited by hypothalamic stimulation. On the other hand, the same doses failed to modify the sleep-wakefulness cycle to any significant degree throughout the study period of 4 hours. On the grounds of these and previous data, the possible brain site of the glutaurine action is discussed.
Kukorelli
T
T
Feuer
L
L
Juhász
G
G
Détári
L
L
D000374:Aggression / Q000187:drug effects*; D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D005973:Glutamine / Q000031:analogs & derivatives* / Q000494:pharmacology; D007031:Hypothalamus / Q000502:physiology; D008297:Male; D011930:Reaction Time / Q000187:drug effects; D012894:Sleep Stages / Q000187:drug effects*; D013654:Taurine / Q000031:analogs & derivatives* / Q000494:pharmacology; D014851:Wakefulness / Q000187:drug effects*
D005973:Glutamine; D013654:Taurine; C020903:glutaurine