The distribution of mercury in various tissues of guinea-pigs after application of dental amalgam fillings (a pilot study).
Mercury accumulation in brain, kidney, liver and heart following insertion of amalgam in the teeth of guinea-pigs has been studied. During the accelerated wear of the amalgam in these gnawing animals, a significant mercury accumulation in the above tissues was demonstrated. Finely diffused and abraded amalgam must not be ignored as a source of absorbable mercury.
Fredin
B
B
Department of Physiological Chemistry IV, University of Lund, Sweden.
D000818:Animals; D001923:Brain Chemistry; D003723:Dental Amalgam / Q000493:pharmacokinetics*; D003793:Dental Restoration, Permanent; D006168:Guinea Pigs; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008628:Mercury / Q000032:analysis*; D009206:Myocardium / Q000032:analysis; D010865:Pilot Projects; D014018:Tissue Distribution
D003723:Dental Amalgam; D008628:Mercury