Improvement of subcutaneous nutritional blood flow in the forefoot by hydroxyethylrutosides in patients with arterial insufficiency: case studies.
Four patients with bilateral arterial insufficiency were treated with i.v. hydroxyethylrutoside for three days (1.5 grs twice a day). All patients experienced relief of symptoms. By continuous registration of subcutaneous nutritional blood flow in the forefoot (by 133Xenon clearance technique) a significant increase in nutritional blood flow of 33% on the average during the second and third hour after medication could be demonstrated. The drug seems to be of use in treating subacute occlusions and thrombosis of arteries in the lower extremity.
R
R
Jelnes
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O
Gaardsting
A
A
Holm
D000368:Aged; D001161:Arteriosclerosis / Q000188:drug therapy / Q000503:physiopathology*; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D005528:Foot / Q000098:blood supply*; D006801:Humans; D006896:Hydroxyethylrutoside / Q000627:therapeutic use*; D007383:Intermittent Claudication / Q000188:drug therapy / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow / Q000187:drug effects; D012431:Rutin / Q000031:analogs & derivatives*; D012867:Skin / Q000098:blood supply; D013997:Time Factors
D006896:Hydroxyethylrutoside; D012431:Rutin