[Several homeostatic renal functions in hypertensive and nephrotic syndromes of chronic functionally compensated glomerulonephritis].
Homeostatic renal functions in nephrotic syndrome (NS) and arterial hypertension were studied the data on 240 patients with functionally compensated chronic glomerulonephritis (CGN). Benign arterial hypertension did not make a considerable effect on renal functions. In NS there was a selective decrease in the functions, particularly affected in the tubulointerstitial component (TIC) of CGN (concentration and ammonium secretory functions). These functions were affected to the maximum in proteinuria over 9.0 g/day. The NS adverse effect on renal transport processes was not dependent on the TIC presence. In CGN accompanied by moderate proteinuria, even a moderate decrease in renal concentration function or a considerable decrease in ammonium secretory function suggested the TIC presence. Against a background of the NS the presence of CGN TIC could be supposed only in the detection of maximum urine osmolarity not exceeding 600 mmol/l.
Brodskiĭ
M A
MA
Ratner
M Ia
MIa
D000293:Adolescent; D000328:Adult; D000641:Ammonia / Q000652:urine; D005260:Female; D005921:Glomerulonephritis / Q000503:physiopathology*; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D007668:Kidney / Q000503:physiopathology*; D007671:Kidney Concentrating Ability; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000503:physiopathology*; D011507:Proteinuria / Q000175:diagnosis / Q000209:etiology
D000641:Ammonia
Nekotorye gomeostaticheskie pochechnye funktsii pri gipertonicheskom i nefroticheskom sindromakh khronicheskogo funktsional'no kompensirovannogo glomerulonefrita.