[Biosynthesis of immunoglobin G in a cell-free system].
Optimal conditions are selected to study biosynthesis of proteins by the microsomal cell-free system. It is established that incorporation of the radioactive precursor into anew synthesized proteins by microsomes decreases in a series: the liver, spleen, lymph nodes, bone marrow. It is shown that under malignant growth considerably higher amount of protein with the antigenic properties of immunoglobulin C is synthesized in the spleen of leukemic rats than in other organs of control leukemic animals.
Korotkoruchko
V P
VP
Polishchuk
A S
AS
D000818:Animals; D002474:Cell-Free System; D007074:Immunoglobulin G / Q000096:biosynthesis*; D007942:Leukemia, Experimental / Q000276:immunology / Q000378:metabolism; D008297:Male; D008861:Microsomes / Q000276:immunology / Q000378:metabolism*; D009928:Organ Specificity; D051381:Rats; D011919:Rats, Inbred Strains
D007074:Immunoglobulin G
Issledovanie biosinteza immunoglobulina G v beskletochnoĭ sisteme.