Giant cell myocarditis associated with lymphoma: an immunocytochemical study.
A case of giant cell myocarditis in a patient with non-Hodgkin's lymphoma is reported. To our knowledge, this is a previously unrecorded association and supports the hypothesis that the aetiology of giant cell myocarditis is related to a changed immune state. Immunohistochemical investigation of this case with a panel of monoclonal antibodies against a range of leucocyte and muscle antigens supports the view that the giant cells have a histiocytic rather than a myogenic origin.
Nuffield Department of Pathology, University of Oxford, John Radcliffe Hospital.
S A
SA
Hales
J M
JM
Theaker
K C
KC
Gatter
D006801:Humans; D008198:Lymph Nodes / Q000276:immunology / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D009206:Myocardium / Q000473:pathology