[Comparative study of the effect of L-lysine-L-oxidase from Trichoderma harzianum Rifai and Trichoderma viride on nucleic acid synthesis in human tumor cells in vitro].
L-lysine-alpha-oxidase, a new fungal enzyme catalyzing oxidative deamination of L-lysine, exerts an inhibitory effect on DNA, RNA and protein synthesis in human cells of carcinoma ovarius (CaOv) in vitro.
Khaduev
S Kh
SKh
Zhukova
O S
OS
Dobrynin
Ia V
IaV
Soda
K
K
Berezov
T T
TT
D000594:Amino Acid Oxidoreductases / Q000494:pharmacology*; D002478:Cells, Cultured; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D003864:Depression, Chemical; D005260:Female; D006801:Humans; D003904:Mitosporic Fungi / Q000201:enzymology*; D009363:Neoplasm Proteins / Q000096:biosynthesis; D010051:Ovarian Neoplasms / Q000378:metabolism; D012334:RNA, Neoplasm / Q000096:biosynthesis*; D014242:Trichoderma / Q000201:enzymology*
D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D000594:Amino Acid Oxidoreductases; C041123:L-lysine oxidase
Sravnitel'noe izuchenie vliianiia L-lizin-L-oksidazy iz Trichoderma harzianum Rifai i Trichoderma viride na sintez nukleinovykh kislot v opukholevykh kletkakh cheloveka in vitro.