[Effect of pancreatic DNAse on the nuclear DNA topology of Candida tropicalis yeasts].
It has been shown that pancreatic DNAase added to the nutritious medium caused the change in the nuclear DNA topology of asporogenic Candida tropicalis yeast. DNA conformative changes are due to the unwinding of supertwisted molecules as a result of single-strand ruptures formation which induce DNA synthesis acceleration, cell growth and division.
F G
FG
Kupriianova
M N
MN
Davydova
N N
NN
Kuznetsova
V G
VG
Vinter
D000818:Animals; D002175:Candida / Q000187:drug effects* / Q000378:metabolism; D002455:Cell Division / Q000187:drug effects; D002467:Cell Nucleus / Q000187:drug effects* / Q000378:metabolism; D002499:Centrifugation, Density Gradient; D004271:DNA, Fungal / Q000032:analysis / Q000378:metabolism*; D004277:DNA, Single-Stranded / Q000378:metabolism; D004278:DNA, Superhelical / Q000378:metabolism; D003851:Deoxyribonucleases / Q000494:pharmacology*; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D010179:Pancreas / Q000201:enzymology*; D013997:Time Factors; D014461:Ultracentrifugation
D004271:DNA, Fungal; D004277:DNA, Single-Stranded; D004278:DNA, Superhelical; D003851:Deoxyribonucleases
Vliianie pankreaticheskoĭ DNKazy na topologiiu iadernoĭ DNK drozhzheĭ Candida tropicalis.