Synthesis and antibacterial activity of novel aminothiazolyl beta-lactam derivatives.
The synthesis and in vitro antibacterial profile of a series of (Z)-(2-amino-4-thiazolyl)-[(2,3-dialkoxypropoxy)imino]acetyl derivatives of 7-aminocephalosporanic acid and 3-aminomonobactamic acid are reported.
Skotnicki
J S
JS
Steinbaugh
B A
BA
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002511:Cephalosporins / Q000138:chemical synthesis; D013329:Structure-Activity Relationship; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D047090:beta-Lactams / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D013844:Thiazoles; D047090:beta-Lactams