U.v. wavelength dependence for the induction of ornithine decarboxylase activity in hairless mouse epidermis.
Induction of mouse epidermal ornithine decarboxylase activity by u.v. radiation has been studied with a monochromator. Dose-response studies were carried out with 10 nm increments between 260 and 320 nm. Time-course studies were carried out at 280, 290 and 300 nm. Ornithine decarboxylase activity, assessed at 24 h post-irradiation, was induced in a dose-dependent fashion between 260 and 310 nm with peak activity at 280-290 nm. These data suggest that the chromophore is a protein.
A R
AR
Young
M J
MJ
Connor
N J
NJ
Lowe
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004790:Enzyme Induction / Q000528:radiation effects; D004817:Epidermis / Q000201:enzymology / Q000528:radiation effects; D005260:Female; D051379:Mice; D008812:Mice, Hairless; D009955:Ornithine Decarboxylase / Q000096:biosynthesis* / Q000528:radiation effects; D012867:Skin / Q000201:enzymology* / Q000528:radiation effects; D013997:Time Factors; D014466:Ultraviolet Rays
D009955:Ornithine Decarboxylase