Inactivation and inhibition of African swine fever virus by monoolein, monolinolein, and gamma-linolenyl alcohol. Brief report.
Monoolein, monolinolein and (most strongly) gamma-linolenyl alcohol inactivate ASF virus and inhibit its replication in Vero cells at 25 micrograms/ml while at 10 micrograms/ml no inactivation occurs but inhibition of replication in tissue culture is observed. This suggests two possibly different action mechanisms.
Sola
A
A
Rodríguez
S
S
García Gancedo
A
A
Vilas
P
P
Gil-Fernández
C
C
D000818:Animals; D002460:Cell Line; D002522:Chlorocebus aethiops; D006692:Classical Swine Fever Virus / Q000187:drug effects*; D005233:Fatty Alcohols / Q000494:pharmacology*; D005989:Glycerides / Q000494:pharmacology*; D007700:Kinetics; D014779:Virus Replication / Q000187:drug effects
D005233:Fatty Alcohols; D005989:Glycerides; C005953:monoolein; C048627:monolinolein; C037936:linolenyl alcohol