An unusual presentation of non-Hodgkin's lymphoma (NHL) in a child.
A rare case of a primary early T-cell non-Hodgkin's lymphoma (NHL) in the bronchus of a 10 year old boy is presented. Although histological examination of the biopsied material was compatible with the diagnosis of NHL or carcinoma, the use of monoclonal antibodies showed it to be an early T-cell NHL and not carcinoma. Accordingly the child was treated using a chemotherapy protocol of the UKCCG for NHL. The patient responded so well to his treatment regime that within 2 weeks of the initiation of chemotherapy there was re-expansion of the collapsed lobe. Six weeks later bronchoscopy was entirely normal with no evidence of residual tumour and now 15 months after the time of diagnosis he remains very well with normal chest X-ray.
T
T
Carr
R F
RF
Stevens
H B
HB
Marsden
P
P
Morris-Jones
S
S
Kumar
D000911:Antibodies, Monoclonal; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D001999:Bronchoscopy; D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D008297:Male
D000911:Antibodies, Monoclonal