Selective action of mycobacillin on the cellular permeability of Aspergillus niger.
Cells of Aspergillus niger normally release not all but of some specific cell constituents viz., lysine, proline, ATP, Pi, Na+, K+ and Ca2+ in the absence of mycobacillin. Mycobacillin enhances the release of these materials without causing lysis. The time and concentration of mycobacillin for optimum release depends on the nature of the materials involved.
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D000255:Adenosine Triphosphate / Q000378:metabolism; D000935:Antifungal Agents / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects* / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004573:Electrolytes / Q000378:metabolism; D007700:Kinetics; D009158:Mycobacillin / Q000494:pharmacology*
D000935:Antifungal Agents; D004573:Electrolytes; D009158:Mycobacillin; D000255:Adenosine Triphosphate