Biopsy of the scalene fat pad in carcinoma of the cervix uteri metastatic to the periaortic lymph nodes.
Fifty-five patients with squamous cell carcinoma of the cervix uteri metastatic to high common iliac or periaortic lymph nodes underwent biopsy of the left scalene fat pad as part of a prospective clinical trial. Patients without metastasis to the scalene nodes were subsequently treated with extended field radiation therapy and were then eligible for a randomized trial of systemic chemotherapy. Only four patients were found to have micrometastases to the scalene fossa. This figure is appreciably lower than that reported in previous literature. While geographic failure continues to be a problem for this group of patients, routine use of left scalene fat pad biopsy before treatment is not recommended.
Section of Gynecologic Oncology, Indiana University Medical Center, Indianapolis.
F B
FB
Stehman
B N
BN
Bundy
P
P
Hanjani
W C
WC
Fowler
G
G
Abdulhay
C W
CW
Whitney
D000273:Adipose Tissue / Q000473:pathology*; D000328:Adult; D000368:Aged; D001012:Aorta, Abdominal; D001707:Biopsy, Needle; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D002945:Cisplatin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009132:Muscles / Q000473:pathology*; D009334:Neck Muscles / Q000473:pathology*; D009367:Neoplasm Staging; D011446:Prospective Studies; D012307:Risk Factors; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy
D002945:Cisplatin; D006918:Hydroxyurea