Premalignant lesions of the larynx: pathological prognostic factors.
Eighty-seven precancerous lesions of the larynx were studied; 46 showed keratosis, 31 slight dysplasias, five severe dysplasias, and five carcinomas in situ. The average follow-up was 3.8 years per patient, and malignant degeneration was observed in nine of them (10.3%). This arose on a pre-existing dysplasia in eight cases, and in the other on a hyperkeratosis. Dyskeratosis was observed in 12 cases, half of which degenerated, this being the group of worst prognosis.
Department of Pathology, Hospital N.S. de Covadonga, University of Oviedo, Spain.
J R
JR
Riera Velasco
C
C
Suárez Nieto
C
C
Pedrero de Bustos
C
C
Alvarez Marcos
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007642:Keratosis / Q000473:pathology; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology*; D011379:Prognosis; D012189:Retrospective Studies