Absorption of cholesterol and beta-sitosterol from cigarette smoke in Macaca mulatta.
When smoke from single cigarettes containing [4-14C]cholesterol or beta-[4-14C]sitosterol was delivered to the lungs of Rhesus macaques, plasma contained radiolabeled sterols up to 50 days later. Since cholesterol, as well as plant sterols (campesterol, stigmasterol and beta-sitosterol), are normally present in cigarette smoke, our observations suggest that protracted absorption of sterols occurs after cigarette smoking.
Malinow
M R
MR
McLaughlin
P
P
Aigner-Held
R
R
Upson
B
B
Isabelle
L M
LM
Connor
W E
WE
Lin
D
D
D000818:Animals; D002250:Carbon Radioisotopes; D002784:Cholesterol / Q000378:metabolism*; D005260:Female; D007408:Intestinal Absorption; D008168:Lung / Q000378:metabolism; D008253:Macaca mulatta; D010947:Plants, Toxic; D012855:Sitosterols / Q000378:metabolism*; D012906:Smoke / Q000032:analysis*; D014026:Nicotiana / Q000032:analysis*
D002250:Carbon Radioisotopes; D012855:Sitosterols; D012906:Smoke; C025473:gamma-sitosterol; D002784:Cholesterol