A genetic association between microcephaly and lymphedema.
We discuss a family in which microcephaly and lymphedema are co-segregating as an apparently autosomal or X-linked dominant trait. A review of each malformation is presented with reference to the known genetic patterns of each. This combination of microcephaly and lymphedema may be a unique syndrome, previously undescribed because of subtleties of expression in affected individuals.
Crowe
C A
CA
Dickerman
L H
LH
D005534:Foot Diseases / Q000151:congenital / Q000235:genetics; D005799:Genes, Dominant; D006801:Humans; D007231:Infant, Newborn; D008209:Lymphedema / Q000151:congenital / Q000235:genetics*; D008297:Male; D008831:Microcephaly / Q000235:genetics*; D010375:Pedigree