Enkephalinergic-cholinergic interaction in the rat globus pallidus: a pre-embedding double-labeling immunocytochemistry study.
The synaptic relationships between leucine-enkephalin containing axon terminals and cholinergic neurons in the rat globus pallidus were studied at both light and electron microscopic levels using a high resolution pre-embedding double-labeling immunocytochemical method. Results indicated that leucine-enkephalin terminals very rarely form monosynaptic connections with cholinergic neurons in the rat globus pallidus, suggesting that enkephalinergic neostriatal efferents probably have little monosynaptic influences on the activities of pallidal cholinergic neurons.
Chang
H T
HT
Department of Anatomy and Neurobiology, University of Tennessee, Memphis, College of Medicine 38163.
Penny
G R
GR
Kitai
S T
ST
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D001560:Benzidines; D002799:Cholinergic Fibers / Q000166:cytology*; D004743:Enkephalin, Leucine / Q000032:analysis*; D005917:Globus Pallidus / Q000032:analysis / Q000166:cytology*; D006046:Gold; D006735:Horseradish Peroxidase; D007150:Immunohistochemistry; D051381:Rats; D012834:Silver; D013569:Synapses / Q000648:ultrastructure*
D001560:Benzidines; D012834:Silver; D004743:Enkephalin, Leucine; D006046:Gold; D006735:Horseradish Peroxidase