[Peripheral neuropathy in severe mixed cryoglobulinemia syndrome].
A syndrome of polyneuropathy and cryoglobinemia is reported in a 76-year-old woman. Nerve biopsy showed severe demyelination and vascular involvement was demonstrated in a muscle biopsy. Peripheral neuropathy is discussed in the context of the Gougerot-Sjögren syndrome, associated with cryoglobins in the blood. Prompt treatment of this disease should be initiated and consists mainly of plasmapheresis.
Thenint
J P
JP
Service de neurologie, VASTEL, Centre hospitalier regional et universitaire de Caen, France.
Penniello
M J
MJ
Chapon
F
F
Viader
F
F
Beaudoin
A
A
Morin
P
P
D000368:Aged; D001369:Axons / Q000648:ultrastructure; D003449:Cryoglobulinemia / Q000473:pathology*; D003711:Demyelinating Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009138:Musculocutaneous Nerve / Q000473:pathology; D009186:Myelin Sheath / Q000648:ultrastructure; D009410:Nerve Degeneration; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D011115:Polyneuropathies / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000473:pathology*
Neuropathie Périphérique Cryoglobulinémie Mixte Syndrome Sec.