[Possible role of embryonic surface antigens in forming the autostimulus of tumor cell proliferation].
It is shown that DNA synthesis intesifies in a mixed culture of cells of the tumours of different histogenesis, induced by monkey adenovirus SA7(C8) and chemical carcinogens, with syngenic and allogenic cells of an early embryo. This intensification of the synthesis in tumour cells is due to the contact of surfaces participating in the cell response but not to the soluble factors because when the embryo cells are placed into the milliporous chamber, the described effect is inhibited.
V S
VS
Erkhov
A I
AI
Ageenko
D000818:Animals; D000954:Antigens, Surface / Q000276:immunology*; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000276:immunology* / Q000378:metabolism; D002478:Cells, Cultured; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004622:Embryo, Mammalian / Q000276:immunology*; D005260:Female; D005865:Gestational Age; D006706:Homeostasis; D051379:Mice; D008808:Mice, Inbred CBA; D011247:Pregnancy
D000954:Antigens, Surface; D004273:DNA, Neoplasm
Vozmozhnaia rol' émbrional'nykh poverkhnostnykh antigenov v formirovanii autostimula proliferatsii opukholevykh kletok.