[Dynamics of morpho-functional changes in gastrin-producing cells of the stomach after electric stimulation of the vagus nerve].
In 25 white rats, direct stimulation of the vagus nerve increased the average diameter of secretory granules and decreased their number and volume, thus reflecting the release of gastrin during first 5 min after the stimulation. Subsequent increase in volume of nucleus, nucleolus, endoplasmatic reticulum, mitochondria and Golgi complex suggest rapid activation of hormone synthesis in G cells under vagostimulation. The data obtained allow to revise the existing concepts of gastrin release from cells and of ultrastructural criteria of this process.
S G
SG
Khomeriki
I A
IA
Morozov
D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004558:Electric Stimulation; D005753:Gastric Mucosa / Q000166:cytology / Q000378:metabolism* / Q000648:ultrastructure; D005755:Gastrins / Q000378:metabolism*; D008297:Male; D009940:Organoids / Q000648:ultrastructure; D051381:Rats; D014630:Vagus Nerve / Q000502:physiology*
D005755:Gastrins
Dinamika morfo-funktsional'nykh izmeneniĭ v gastrinprodutiruiushchikh kletkakh zheludka posle élektricheskoĭ stimuliatsii bluzhdaiushchego nerva.