In vitro cytostatic activity of chromatographic fractions of extracts from some species of compositae.
Three species of the family of Compositae were extracted, partitioned and fractioned on silica gel column. The chromatographic fractions were investigated for cytostatic activity in vitro against human KB (human carcinoma of nasopharynx) cell line. The most interesting results were obtained with the first eight fractions of Senecio inaequidens DC, chloroformic extract, which showed marked cytostatic activity and appeared worthy of further investigations.
P
P
Barbetti
G
G
Fardella
I
I
Chiappini
A
A
Menghini
A
A
Furlani Candiani
V
V
Scarcia
D000970:Antineoplastic Agents / Q000302:isolation & purification*; D002277:Carcinoma / Q000188:drug therapy*; D002460:Cell Line; D002478:Cells, Cultured; D002850:Chromatography, Gel / Q000379:methods; D006801:Humans; D007558:Italy; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy*; D010936:Plant Extracts / Q000032:analysis* / Q000502:physiology
D000970:Antineoplastic Agents; D010936:Plant Extracts