Endolymphatic stromal myosis of the uterus with metastasis to ovary and recurrence in vagina.
A 24-year-old woman underwent a supracervical hysterectomy with findings of an endolymphatic stromal myosis (ESM) with vascular invasion as a submucosal tumor of the uterine fundus. Four years later, metastasis of ESM in the right ovary was found after salpingo-oophoréctomy. Parametrial masses and a tumor infiltrated cervical stump revealed the same structure of ESM after operation. Though subtotal excision of the pelvic and vaginal recurrences nine years after the first operation for ESM and in spite of oral administration of danazol and duphaston (hydrogesterone), a recurrent vaginal tumor developed after the fourth operation and local application of chemotherapy with 5-fluorouracil was given. At present, the patient's condition is stable without distant metastasis.
T J
TJ
Yu
I
I
Iwasaki
H
H
Horie
J
J
Tamaru
A
A
Takahashi
D000328:Adult; D002584:Cervix Uteri / Q000473:pathology; D004717:Endometrium / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D010051:Ovarian Neoplasms / Q000556:secondary*; D010053:Ovary / Q000473:pathology; D012509:Sarcoma / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology*; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000556:secondary