Renal function following surgical correction of vesico-ureteric reflux in childhood.
To assess the effectiveness of the surgical correction of vesico-ureteric reflux, current renal function was determined in 56 children with scarred kidneys who had undergone ureteric reimplantation between 1978 and 1983. The children were aged between 2 and 15 years, had no coexisting urological disease and a glomerular filtration rate (GFR) of less than 90 ml/min/1.73 m2. In the 32 patients who had bilateral reimplantation of ureters draining bilaterally scarred kidneys the improvement in GFR following surgery was highly significant (P less than 0.001), with improvement occurring in 75%. The greatest improvement was in patients where the GFR was less than 50 ml/min/1.73 m2 (29%). Individual kidney GFR was estimated in 42 kidneys and 81% improved after surgery. This improvement was highly significant (P less than 0.001).
D J
DJ
Scott
H N
HN
Blackford
M R
MR
Joyce
A R
AR
Mundy
C H
CH
Kinder
G B
GB
Haycock
C
C
Chantler
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000503:physiopathology* / Q000601:surgery; D011184:Postoperative Period; D012189:Retrospective Studies; D014513:Ureter / Q000601:surgery; D014718:Vesico-Ureteral Reflux / Q000503:physiopathology / Q000601:surgery*