Motor behaviour and visual discrimination after neonatal and adult hemidecortication in the rabbit.
In 5 groups of rabbits (0-1, 2-3, 4-5, 6-7 and 12-13 weeks old) the left frontal, parieto-temporal and occipital cortex were removed. Beginning two weeks after the operations the hopping reaction was tested during 15 weeks. It was found in the groups operated 0-1, 2-3 and 4-5 weeks after birth, that the hopping reaction developed normally. This was not the case in the animals operated 6-7 and 12-13 weeks after birth. Brightness discrimination with the left and right eye was tested in the same animals, beginning 12 weeks after the operation. Contrary to the motor system, no age-dependent recovery was found in the visual system. In all age groups, brightness discrimination with the eye contralateral to the lesion was impaired.
van Hof
M W
MW
Department of Physiology I, Erasmus Universiteit Rotterdam, The Netherlands.
Hobbelen
J F
JF
De Vos-Korthals
W H
WH
D000375:Aging / Q000502:physiology*; D000818:Animals; D002541:Cerebral Decortication; D004193:Discrimination Learning / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology; D009043:Motor Activity / Q000502:physiology*; D009778:Occipital Lobe / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology; D010775:Photic Stimulation; D011817:Rabbits; D014795:Visual Pathways / Q000254:growth & development / Q000502:physiology*