A comparative study of pipemidic acid and nitrofurantoin in the treatment of uncomplicated urinary tract infections.
In an open uncontrolled trial 60 women with confirmed uncomplicated urinary tract infections were randomly allocated to receive either pipemidic acid (Septidron; Ethimed) or nitrofurantoin for 10 days. Urine cultures were done on day 1 and day 10. No statistical difference was found in the subjective and objective assessments of the response to the two medications and it is concluded that pipemidic acid is a satisfactory and effective alternative to nitrofurantoin in the treatment of uncomplicated urinary tract infections in women.
Department of Pharmacology, University of Pretoria.
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EC
Meyer
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Schoeman
D000328:Adult; D005260:Female; D006801:Humans; D009539:Nicotinic Acids / Q000627:therapeutic use*; D009582:Nitrofurantoin / Q000627:therapeutic use*; D010876:Pipemidic Acid / Q000627:therapeutic use*; D013997:Time Factors; D014552:Urinary Tract Infections / Q000188:drug therapy*
D009539:Nicotinic Acids; D009582:Nitrofurantoin; D010876:Pipemidic Acid