[Clinical studies on cefuzonam in the field of obstetrics and gynecology].
Cefuzonam (CZON, L-105), a cephem type antibiotic, was clinically studied in the field of obstetrics and gynecology. The results are summarized as follows: CZON 1-2 g was administered by injection twice daily to 11 cases of infections (4 of endometritis, 2 of pyometra, 3 of adnexitis and peritonitis, 1 of abdominal abscess, and 1 of puerperal fever). Clinical efficacy was excellent in 2 cases and good in 9 cases, with a very high overall efficacy rate of 100%. Slight elevations of GOT and GPT in 1 case were noted in clinical laboratory tests. No side effects attributable to the drug were noted. CZON is considered to be a useful drug for obstetric and gynecological infections.
Department of Obstetrics and Gynecology, Asahikawa Medical College.
A
A
Souma
K
K
Yamashita
M
M
Ishikawa
Y
Y
Yorozu
T
T
Asakawa
T
T
Shimizu
H
H
Haga
S
S
Saitoh
T
T
Saitoh
T
T
Hasegawa
D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy*; D015296:Ceftizoxime / Q000031:analogs & derivatives*; D002511:Cephalosporins / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D006801:Humans
D002511:Cephalosporins; C049934:cefuzonam; D015296:Ceftizoxime