On the nature of the active component of haematoporphyrin derivative--Part 2.
It has been suggested recently that neither an ester nor an ether linkage was present in the tumour-localising component of Photofrin II (PFII) (a commercial preparation of DHE). We now report that our chemical and spectroscopic studies, establish the presence of an ester linkage with the possibility that an ether linkage may also be involved.
Department of Chemistry, Paisley College of Technology, Renfrewshire, Scotland, U.K.
R W
RW
Boyle
W F
WF
Keir
A H
AH
MacLennan
G
G
Maguire
T G
TG
Truscott
D002851:Chromatography, High Pressure Liquid; D006415:Hematoporphyrins / Q000032:analysis*; D006868:Hydrolysis; D013055:Spectrophotometry, Infrared
D006415:Hematoporphyrins