[Locus ceruleus: the regulation of hemato-encephalic barrier function normally and under emotional stress].
To study the role of locus ceruleus in maintaining the blood-brain barrier function in conditions of emotional stress, the blood-brain barrier permeability was estimated after locus ceruleus damaging with DSP4 (N-2-chloroethyl-N-ethyl-2-bromobenzylamine). The importance of locus ceruleus for the integrity of blood-brain barrier functions in control animals and especially in rats exposed to emotional stress was revealed. The data obtained prove the homeostatic role of locus ceruleus, which is the most prominent in conditions of emotional stress.
Belova
T I
TI
Petrova
N V
NV
Jonsson
G
G
D000818:Animals; D001596:Benzylamines / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D001812:Blood-Brain Barrier / Q000187:drug effects; D008125:Locus Coeruleus / Q000187:drug effects / Q000502:physiology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000503:physiopathology*; D013997:Time Factors
D001596:Benzylamines; C012102:DSP 4
Locus ceruleus: reguliatsiia funkstii gematoéntsefalicheskogo bar'erav norme i v usloviiakh émotsional'nogo stressa.