Prevention by hypothermic cap of antiblastic induced-alopecia.
Adriamycin, one of most effective antitumor drugs, is characterized by high toxicity. The adriamycin-induced alopecia is frequent (80-97% of patients) and rapidly shows itself (already after first treatment). Such toxic effect, so unpleasant particularly to female patients, was largely prevented in our experience (Gynecological Oncology Service) with the utilization of hypothermic caps. These caps, reducing the drug absorption above the scalp, allows limiting the hair loss. The result obtained (reduction of severe alopecia in 34% of patients) encourage the use of such a method to improve the life quality of patients.
C
C
Villani
P
P
Inghirami
D
D
Pietrangeli
S
S
Tomao
G
G
Pucci
D000505:Alopecia / Q000139:chemically induced / Q000517:prevention & control*; D017679:Cryotherapy; D004317:Doxorubicin / Q000009:adverse effects*; D005260:Female; D006801:Humans
D004317:Doxorubicin