A trimeric esterase in the common shrew.
A variable kidney esterase found in the common shrew has a trimeric structure as indicated by the phenotypes of heterozygotes. From substrate specificity and tissue distribution this enzyme appears to be homologous with esterase-6 of the mouse, also a trimeric enzyme. It is suggested that a trimeric esterase may have been a feature of early eutherian mammals.
Searle
J B
JB
D000818:Animals; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000235:genetics; D004950:Esterases / Q000235:genetics* / Q000378:metabolism; D006579:Heterozygote; D007668:Kidney / Q000201:enzymology; D051379:Mice / Q000235:genetics; D010641:Phenotype; D012689:Sequence Homology, Nucleic Acid; D012788:Shrews / Q000235:genetics* / Q000378:metabolism; D013045:Species Specificity; D013379:Substrate Specificity
D004950:Esterases; D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase