The serum apo B and apo E in rats following cholesterol diet and thymus treatment.
The serum levels of apo B and apo E in rats fed on a diet rich in cholesterol before and after thymus treatment were determined by the authors. The diet enriched with cholesterol increases the serum levels of apo E and of the large and small species of apo B. After treatment the large apo B and the small one strongly decrease, while apo E increases further. These data support the hypothesis that the dropping of total cholesterol, after thymus treatment, cannot be ascribed to apo E decrease but possibly to B-apoproteins.
Mondola
P
P
Institute of Human Physiology, II. Faculty of Medicine, University of Naples, Italy.
Santangelo
F
F
Falconi
C
C
Belfiore
A
A
D000818:Animals; D001055:Apolipoproteins B / Q000097:blood*; D001057:Apolipoproteins E / Q000097:blood*; D002784:Cholesterol / Q000097:blood; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D008076:Cholesterol, HDL / Q000097:blood; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013949:Thymus Extracts / Q000494:pharmacology*; D014280:Triglycerides / Q000097:blood
D001055:Apolipoproteins B; D001057:Apolipoproteins E; D002791:Cholesterol, Dietary; D008076:Cholesterol, HDL; D013949:Thymus Extracts; D014280:Triglycerides; D002784:Cholesterol