Tobacco intolerance in multiple system atrophy.
In a patient with multiple system atrophy, the ataxia was temporarily exacerbated by cigarette smoking. The phenomenon is attributed to a direct effect of nicotine on the central nervous system, rather than being secondary to autonomic changes. Its prevalence and specificity are currently unknown.
Johnsen
J A
JA
Miller
V T
VT
D001342:Autonomic Nervous System Diseases / Q000150:complications*; D002524:Cerebellar Ataxia / Q000209:etiology; D002531:Cerebellum / Q000187:drug effects; D004401:Dysarthria / Q000209:etiology; D005684:Gait; D006801:Humans; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000009:adverse effects / Q000494:pharmacology; D012791:Shy-Drager Syndrome / Q000150:complications*; D012907:Smoking
D009538:Nicotine