Chromosomal assignment of the gene encoding the human tissue inhibitor of metalloproteinases to Xp11.1-p11.4.
The tissue inhibitor of metalloproteinases (TIMP) is thought to play a regulatory role in connective tissues by forming inactive complexes with those metalloproteinases that are normally responsible for connective tissue turnover. The human gene encoding TIMP has been mapped to the X chromosome in the region Xp11.1-p11.4.
Human Genetic Resources Laboratory, Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, Herts.
N K
NK
Spurr
P N
PN
Goodfellow
A J
AJ
Docherty
D000933:Antifibrinolytic Agents; D002874:Chromosome Mapping; D004247:DNA; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors*; D009693:Nucleic Acid Hybridization; D014178:Translocation, Genetic; D014960:X Chromosome
D000933:Antifibrinolytic Agents; D004247:DNA; D008666:Metalloendopeptidases