Denervated splenopancreatic flap for chronic pancreatitis.
Various surgical procedures have addressed the disabling pain of chronic pancreatitis. Pain control must be weighed against the surgical morbidity and metabolic consequences of operation. Although ductal drainage works well for patients with dilated ducts, a new procedure was devised to avoid the diabetic morbidity of near-total pancreatectomy or pancreaticoduodenectomy in patients with small duct pancreatitis. Five patients have undergone the splenopancreatic flap procedure. The head of the pancreas is resected in a manner similar to near-total pancreatectomy, while the body and tail are denervated by dissection from their bed, with retrograde perfusion from the splenic hilus. All patients are alive a mean of 9 months after operation, and none is diabetic. Only one patient requires narcotic analgesics. Although none is asymptomatic, all have shown significant weight gain, and four of five are vocationally rehabilitated. Flap viability and the absence of transgastric varices have been documented by angiography and CT scanning. Although the durability of pain relief and islet cell function is unknown, these results suggest that this procedure may offer an alternative to major resection in chronic pancreatitis.
G T
GT
Shires
W D
WD
Warren
W J
WJ
Millikan
J M
JM
Henderson
T
T
Hersh
D000328:Adult; D000437:Alcoholism / Q000150:complications; D002908:Chronic Disease; D003714:Denervation; D003922:Diabetes Mellitus, Type 1 / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D009294:Narcotics / Q000627:therapeutic use; D010148:Intractable Pain / Q000628:therapy; D010179:Pancreas / Q000294:innervation*; D010180:Pancreatectomy / Q000379:methods; D010195:Pancreatitis / Q000209:etiology / Q000601:surgery*; D012086:Reoperation; D013154:Spleen / Q000294:innervation*
D009294:Narcotics