Hepatic epithelioid hemangioendothelioma in a young female.
Epithelioid hemangioendothelioma in a young female is reported. Her symptoms were right upper quadrant pain and low-grade fever. Laboratory examinations showed an increased number of white blood cells and an elevated erythrocyte sedimentation rate. Plasma factor VIII:C was increased. The hepatic lesions were demonstrated as low-density areas by CT scan, and multiple nodules with central depression on the surface of the liver were identified by peritoneoscopy. The biopsy specimens showed spindle-shaped tumor cells set in the fibrous and myxohyalinous tissue. The tumor cells were positive for factor VIII-related antigen and Weibel-Palade bodies. The patient received transcatheter arterial embolization therapy using Gelfoam and mitomycin C following which the plasma level of factor VIII was normalized and regression of the tumors was observed.
Division of Gastroenterology, Mitsui Memorial Hospital, Tokyo, Japan.
T
T
Kawabe
K
K
Tagawa
T
T
Unuma
R
R
Takanashi
T
T
Oka
D000293:Adolescent; D005260:Female; D006390:Hemangioendothelioma / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology*; D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D014057:Tomography, X-Ray Computed
D009942:Organometallic Compounds; D015609:Organotechnetium Compounds; C026177:technetium phytate; D010833:Phytic Acid