Applications of multiple quantum coherence to MR imaging.
Another fundamental type of nuclear spin magnetization, multiple quantum coherence, is shown to provide a further means of differentiating materials detected in the magnetic resonance (MR) experiment. A sequence using pulsed magnetic field gradients and radiofrequency pulses is demonstrated to selectively image only lactic acid in a phantom consisting of bottles of water, concentrated lactic acid, and corn oil. In particular, since water dominates the signal in the body, the double quantum experiment also serves as a strong natural suppression technique. These types of experiments are predicted to be useful both in MR spectroscopy and imaging when the more dilute metabolites in tissue are to be examined.
Szeverenyi
N M
NM
Haacke
E M
EM
D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation; D008961:Models, Structural