A rapid chromatographic procedure for the determination of adriamycin, daunomycin and their 13-OH metabolites adriamycinol and daunomycinol.
A rapid chromatographic procedure for the quantitative determination of the anthracycline antibiotics adriamycin and daunorubicin and their chief metabolites adriamycinol and daunorubicinol in plasma and urine is described. The extraction is performed using SEP-PAK silica cartridges. After filtration the eluate is chromatographed on a reversed-phase column.
Erb
N
N
Erttmann
R
R
Landbeck
G
G
D000328:Adult; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D003630:Daunorubicin / Q000031:analogs & derivatives* / Q000032:analysis* / Q000097:blood / Q000652:urine; D004317:Doxorubicin / Q000031:analogs & derivatives* / Q000032:analysis* / Q000097:blood / Q000652:urine; D006801:Humans
D004317:Doxorubicin; C010013:adriamycinol; C000847:daunorubicinol; D003630:Daunorubicin