Early treatment by plasmapheresis in a woman with multiple abortions and the rare blood group p.
Women with the rare blood group p are known to have an increased rate of abortions. The case of a 36-year-old woman is presented who had had 7 spontaneous abortions in the first trimester and no live child. When treated by plasma exchange begun early in pregnancy and continued until the 29th week, she delivered a normal child. Time to begin, amount and length of time necessary to continue plasma exchange in these patients are considered. In addition, the question of which fraction of the anti-PP1Pk could be responsible for abortion is discussed. To our knowledge, this is the first case of a woman of p phenotype with no live children but with multiple abortions treated by this method, which should be seriously considered in similar cases.
Department of Hematology and Blood Bank, Rambam Medical Center, Haifa Israel.
Y
Y
Shechter
I E
IE
Timor-Tritsch
N
N
Lewit
R
R
Sela
C
C
Levene
D000026:Abortion, Habitual / Q000628:therapy*; D000328:Adult; D001789:Blood Group Antigens; D004394:Dydrogesterone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010127:P Blood-Group System; D010956:Plasmapheresis; D011247:Pregnancy; D011248:Pregnancy Complications; D011261:Pregnancy Trimester, First; D013203:Staphylococcal Infections / Q000150:complications; D013997:Time Factors
D001789:Blood Group Antigens; D010127:P Blood-Group System; D004394:Dydrogesterone