Sperm factors related to failure of human in-vitro fertilization.
Two groups of men were retrospectively selected according to their observed success in in-vitro fertilization. Seminal and post-migration sperm samples from a low fertilization rate group (less than or equal to 33% cleaved embryos) have been compared to results obtained from a high fertilization rate group (greater than or equal to 66%). It was found that a low mean value of the amplitude of lateral sperm head displacement and an increased percentage of abnormal acrosomes were related to in-vitro fertilization failure. None of the individual sperm factors studied was found to determine in-vitro fertilization success with certainty; only when they were considered in combination was it possible to predict the likelihood of successful in-vitro fertilization of human oocytes.
C
C
Jeulin
D
D
Feneux
C
C
Serres
P
P
Jouannet
F
F
Guillet-Rosso
J
J
Belaisch-Allart
R
R
Frydman
J
J
Testart
D000177:Acrosome / Q000648:ultrastructure; D000328:Adult; D005298:Fertility; D005307:Fertilization in Vitro; D006801:Humans; D008297:Male; D012661:Semen / Q000502:physiology; D013081:Sperm Motility; D013083:Sperm Transport; D013094:Spermatozoa / Q000166:cytology / Q000502:physiology*