Neuropathology of Seckel syndrome in fetal stage with evidence of intrauterine developmental retardation.
Marked intrauterine developmental retardation in a fetal case of Seckel syndrome was morphologically defined in the 29th week of gestation by comparing with a large number of length-matched and age-matched controls. Telencephalic micrencephaly with reduced neuroblast production, retarded functional differentiation of the pituitary gland, and generalized hypotrophy with craniofacial stigmata were observed.
Hori
A
A
Department of Neuropathology, Universität Göttingen, Federal Republic of Germany.
Tamagawa
K
K
Eber
S W
SW
Westmeier
M
M
Hansmann
I
I
D000015:Abnormalities, Multiple / Q000473:pathology*; D001921:Brain / Q000002:abnormalities / Q000254:growth & development* / Q000473:pathology; D005260:Female; D005317:Fetal Growth Retardation / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008831:Microcephaly / Q000473:pathology*; D011247:Pregnancy; D013577:Syndrome