Synchrony between cortical neurons in normal and epileptogenic cortex of monkey.
A series of experiments was carried out to test the hypothesis that epileptogenic cortex contains a higher degree of synchrony between neurons than does nonepileptogenic cortex. Four hundred pairs of neurons were recorded extracellularly from precentral cortex of four normal and four epileptic monkeys. For each 5 min of recording, a cross-correlation and coefficient of synchrony were calculated for each pair of neurons. Although there was some degree of synchrony between neurons, there was no apparent increase in synchronous firing within the epileptogenic focus.
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Wyler
D000818:Animals; D002540:Cerebral Cortex / Q000503:physiopathology*; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology*; D008253:Macaca mulatta; D008297:Male; D009474:Neurons