[Changes in telogen rate, hair density, hair diameter and rate of growth in androgenetic alopecia of the male. Simultaneously a contribution to the significance of dysplastic hair].
In a pilot study, comparative measurements of frontal and occipital trichograms, hair density, hair diameter and hair growth rate were performed on 26 male volunteers (ages 20-33 years) with androgenetic alopecia between stages II and V (Norwood scale). In the frontal region, the proportion of telogen hair was, in general, pathologically higher and increased according to stage. The density of the frontal hair was significantly lower (166 +/- 28/cm2) compared with that of the occipital region (193 +/- 24/cm2) and decreased according to stage. The average hair diameter in the higher Norwood stages decreased similarly in both the frontal and occipital regions, as shown by the correspondence between the two measurement points (frontal, 0.068 +/- 0.011 mm; occipital, 0.069 +/- 0.010 mm). Anagen and dysplastic hair from both the frontal and occipital regions was significantly thicker than telogen hair (0.07 mm vs 0.05 mm). The frontal growth rate (0.355 +/- 0.024 mm/day) was significantly lower than that of the occipital region (0.389 +/- 0.021 mm/day). In addition, the frontal growth rate decreased according to stage. Dysplastic hair exhibited high growth rates and diameters similar to those of typical anagen hair. In our opinion, dysplastic hair is growing hair, the roots of which have been artificially modified by plucking. - These intra-individual comparisons of frontal and occipital regions showed a reduction in the anagen phase, density, diameter and growth rate of the endangered frontal hair. A reduction in the size and dividing activity of the matrix is indicated by our data. It seems that these regressive changes occur primarily without a prior indication of accelerated hair growth.
Runne
U
U
Martin
H
H
D000328:Adult; D000505:Alopecia / Q000175:diagnosis / Q000503:physiopathology*; D000728:Androgens / Q000502:physiology; D006197:Hair / Q000254:growth & development*; D006201:Hair Diseases / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008297:Male; D012535:Scalp / Q000503:physiopathology
D000728:Androgens
Veränderungen von Telogenrate, Haardichte, Haardurchmesser und Wachstumsgeschwindigkeit bei der androgenetischen Alopezie des Mannes. Zugleich ein Beitrag zur Bedeutung dysplastischer Haare.