[Plasma enzymes inactivating alkaloids].
It was shown that rat blood plasma contains two enzymes that inactivate alkaloids by transforming them into N-oxides. Both enzymes are hemoproteins: one of them consists of three different polypeptides with Mr of 63, 35 and 12 kD, while the other one is a single polypeptide with Mr of 73 kD. Both enzymes exhibit cooperative properties.
N R
NR
Elaev
L D
LD
Evdokimov
A V
AV
Ryzhakov
D000470:Alkaloids / Q000037:antagonists & inhibitors* / Q000097:blood / Q000378:metabolism; D000818:Animals; D001115:Arecoline / Q000037:antagonists & inhibitors; D001285:Atropine / Q000037:antagonists & inhibitors; D001798:Blood Proteins / Q000302:isolation & purification; D002848:Chromatography, DEAE-Cellulose; D003497:Cyclic N-Oxides / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D004798:Enzymes / Q000097:blood*; D066298:In Vitro Techniques; D008970:Molecular Weight; D051381:Rats
D000470:Alkaloids; D001798:Blood Proteins; D003497:Cyclic N-Oxides; D004798:Enzymes; D001115:Arecoline; D001285:Atropine
Fermenty plazmy krovi, inaktiviruiushchie alkaloidy.