Regression of valvular aortic stenosis due to homozygous familial hypercholesterolemia following plasmapheresis.
A 39-year-old male with homozygous familial hypercholesterolemia confirmed by tissue culture suffered from mild aortic insufficiency and valvular stenosis with a gradient of 20 mm Hg across the aortic valve. Plasmapheresis carried out every 2 weeks for 4 years resulted in a marked reduction in the serum cholesterol level and in a regression of the valvular stenosis, as shown by echocardiography and by left heart catheter.
Keller
C
C
Schmitz
H
H
Theisen
K
K
Zöllner
N
N
D000328:Adult; D001022:Aortic Valve Insufficiency / Q000628:therapy; D001024:Aortic Valve Stenosis / Q000628:therapy*; D002784:Cholesterol / Q000097:blood; D003326:Coronary Circulation; D004452:Echocardiography; D006439:Hemodynamics; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000628:therapy*; D008297:Male; D010956:Plasmapheresis
D002784:Cholesterol