[Characteristics of coronary vasodilation reserve in partial restriction and subsequent recovery of the coronary blood flow].
The studies were performed on anesthetized dogs using the model of partial controlled blood flow restriction in the left circumflex coronary artery with intact thorax. 70% of blood flow restriction were compensated by coronary vasodilation reserve, evaluated in hyperemia reaction. No rapid reperfusion hyperemia reaction was observed in reperfusion period, while moderate reduction in heart contractility was maintained. Alterations in coronary vessel reactivity could have a certain depressing effect on reperfusion hyperemia reaction. The observed changes were reversible, as coronary vessels retained their dilatation ability in response to an additional ischemic stimulus.
Orlova
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D000818:Animals; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology*; D004285:Dogs; D006940:Hyperemia / Q000503:physiopathology*; D009200:Myocardial Contraction; D010477:Perfusion; D013997:Time Factors; D014664:Vasodilation
Kharakteristika koronarnogo rasshiritel'nogo rezerva pri chastichnom ogranichenii i posleduiushchem vosstanovlenii koronarnogo krovotoka.