Pulmonary lymphoma or pseudolymphoma: a diagnostic dilemma.
The clinical significance of pulmonary pseudolymphoma remains unresolved. We report a case which highlights the lymphoma versus pseudolymphoma dilemma. An elderly lady followed up for more than ten years with a slowly enlarging right lung mass had on biopsy, lymphoid hyperplasia consistent with a lymphoma or pseudolymphoma. Laboratory investigations revealed hyperglobulinemia due to a biclonal gammopathy with elevated serum immunoglobulin M and G fractions. Monoclonal production of immunoglobulin is today considered more indicative of a neoplasia than a hyperplasia.
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D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000276:immunology; D008223:Lymphoma / Q000175:diagnosis* / Q000276:immunology; D008875:Middle Aged; D013997:Time Factors
D007074:Immunoglobulin G; D007075:Immunoglobulin M