Susceptibility of bite wound bacteria to seven oral antimicrobial agents, including RU-985, a new erythromycin: considerations in choosing empiric therapy.
The susceptibility of 93 aerobic and 59 anaerobic bacteria isolated from human and animal bite wounds was determined by agar dilution. No agent tested (penicillin, oxacillin, cephalexin, sulfamethoxazole-trimethoprim, minocycline, erythromycin, and RU-965) was consistently active against all isolates. A total of 21% of the Bacteroides species, all isolated from human bites, were resistant to penicillin; 14 and 18% of the Pasteurella multocida isolates were resistant to erythromycin and oxacillin, respectively.
E J
EJ
Goldstein
D M
DM
Citron
A E
AE
Vagvolgyi
S M
SM
Finegold
D000818:Animals; D000900:Anti-Bacterial Agents; D001733:Bites and Stings / Q000188:drug therapy / Q000382:microbiology*; D001734:Bites, Human / Q000188:drug therapy / Q000382:microbiology*; D002415:Cats / Q000382:microbiology*; D004285:Dogs / Q000382:microbiology*; D004917:Erythromycin / Q000031:analogs & derivatives / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology; D012589:Sciuridae / Q000382:microbiology
D000900:Anti-Bacterial Agents; D004917:Erythromycin