Further investigation of the effect of chronic ethanol on the electric membrane properties of adult DRG neurons in cell culture.
Neural cell cultures were used to investigate the effects of acute and chronic ethanol exposure on electric membrane properties (EMP) of adult mouse dorsal root ganglion (DRG) neurons. These results in combination with results from additional experiments involving chronic exposure to hyposomotic medium provided further support for the hypothesis that the abnormal EMP caused by chronic ethanol exposure involved neuronal membrane adaptation to an ethanol-induced membrane expansion.
Scott
B
B
Lew
J
J
D000222:Adaptation, Physiological; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects; D002478:Cells, Cultured; D004553:Electric Conductivity; D000431:Ethanol / Q000494:pharmacology*; D005727:Ganglia, Spinal; D008564:Membrane Potentials / Q000187:drug effects; D051379:Mice; D009474:Neurons / Q000187:drug effects*; D009997:Osmotic Pressure
D000431:Ethanol