[Substrate specificity of monoamine oxidase from the brain and liver of the human fetus during antenatal ontogenesis].
Dynamics of changes in the monoaminooxidase activity with respect to different substrates is characterized by a number of peculiarities and varies essentially in the process of ripening of the organs. Both in the brain and in the liver tyramine (a substrate of enzymes of types A and B), serotonin and norepinephrine (substrates of type A) and benzyl amine (substrate of type B) are subjected to oxidative deamination: tyramine--most intensely, serotonin and norepinephrine--less intensely and benzyl amine--least intensely.
T G
TG
Skorobogataia
D001679:Biogenic Amines / Q000378:metabolism; D001921:Brain / Q000196:embryology / Q000201:enzymology*; D005260:Female; D005333:Fetus / Q000201:enzymology*; D006801:Humans; D008099:Liver / Q000196:embryology / Q000201:enzymology*; D008928:Mitochondria / Q000201:enzymology*; D008930:Mitochondria, Liver / Q000201:enzymology; D008995:Monoamine Oxidase / Q000378:metabolism*; D011247:Pregnancy; D013379:Substrate Specificity
D001679:Biogenic Amines; D008995:Monoamine Oxidase
Substratnaia spetsifichnost' monoaminoksidazy mozga i pecheni plodov cheloveka v period antenatal'nogo ontogeneza.