Cyanosis of the hands following the use of alphaprodine in dental anaesthesia.
A case is presented of asymptomatic cyanosis of the hands, seen four hours after dental surgery under intravenous, local and inhalational anaesthesia. Alphaprodine hydrochloride, a synthetic opiate and one of the agents used, may produce dilatation of the venous bed with passive venous pooling. Such a mechanism is thought to have occurred in this case, manifesting as cyanosis. A weakly positive intradermal skin test to alphaprodine suggests immediate type hypersensitivity as a possible underlying cause.
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D000293:Adolescent; D000522:Alphaprodine / Q000009:adverse effects*; D000766:Anesthesia, Dental; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D000772:Anesthesia, Local; D003490:Cyanosis / Q000097:blood / Q000139:chemically induced*; D005260:Female; D006225:Hand; D006801:Humans; D007428:Intradermal Tests; D008012:Lidocaine; D008723:Methohexital
D000522:Alphaprodine; D008012:Lidocaine; D008723:Methohexital