Postnatal development of vasopressin mRNA content in supraoptic and paraventricular nucleus of the Wistar rat.
Levels of mRNA coding the vasopressin precursor (VP mRNA) were determined in the supraoptic and paraventricular nucleus during the first month of postnatal development of the Wistar rat by solution hybridization assay and Northern blot analysis. The supraoptic and paraventricular nuclei showed a marked increase in VP mRNA to adult levels during that period. These results indicate an upregulation of vasopressin gene expression in supraoptic and paraventricular nuclei after birth, a period in which vasopressin starts to become involved in kidney function.
van Tol
H H
HH
Snijdewint
F G
FG
Boer
G J
GJ
Burbach
J P
JP
D000818:Animals; D001127:Arginine Vasopressin / Q000096:biosynthesis*; D005260:Female; D008297:Male; D009693:Nucleic Acid Hybridization; D010286:Paraventricular Hypothalamic Nucleus / Q000254:growth & development / Q000378:metabolism*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000032:analysis / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013495:Supraoptic Nucleus / Q000254:growth & development / Q000378:metabolism*
D012333:RNA, Messenger; D001127:Arginine Vasopressin