Risk of malignant lymphoma in Swedish pesticide appliers.
The risk of Hodgkin's disease (HD) and non-Hodgkin lymphoma (NHL) was studied in a cohort of 20,245 Swedish pesticide appliers, who had the licence issued between 1965 and 1976. In this cohort 72% were estimated to have been exposed to phenoxy acid herbicides. The cohort was followed-up in the Swedish Cancer Register from date of licence until Dec. 31, 1982 or until death if prior to that date. The mean follow-up time was 12.2 years. A total of 11 cases with HD and 21 cases with NHL were observed compared to 9.1 and 20.8 expected. The relative risks and the 95% confidence intervals were for HD 1.20 (0.60-2.16) and for NHL 1.01 (0.63-1.54). The relative risk rose, but not to statistical significance however, with increased time since licence for both diagnoses.
Department of Cancer Epidemiology, Karolinska Hospital and Institute, Stockholm, Sweden.
K
K
Wiklund
J
J
Dich
L E
LE
Holm
D000382:Agricultural Workers' Diseases / Q000139:chemically induced*; D005260:Female; D006540:Herbicides / Q000009:adverse effects*; D006689:Hodgkin Disease / Q000139:chemically induced*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000139:chemically induced*; D008297:Male; D011481:Protective Clothing; D012307:Risk Factors; D013548:Sweden
D006540:Herbicides