[Fibronectin concentrations in the plasma of newborn infants and their mothers and various plasma preparations].
The article describes a method for the quantification of plasma fibronectin (FN) by means of electroimmunodiffusion after Laurell. By this means the fibronectin concentrations of healthy, mature newborns as well as of their mothers were determined. The average FN-level of the newborns lies at 33% related to the value for adults and at 48%, respectively, related to the maternal FN-content. There is no difference between male and female newborns. The FN-concentrations of the adults stated by us with 330 and 314 mg/l, respectively, for males and females correspond to the data in literature. Furthermore, the FN-content in plasma preparations was determined, with an average value of 2,356 mg/l this was highest in the factor-VIII-concentrate. The expediency and the prerequisites for a possible fibronectin substitution are discussed.
Klinik für Innere Medizin Theodor Brugsch, Bereiches Medizin (Charité), Humboldt-Universität zu Berlin.
M
M
Backhaus
F
F
Mielke
E
E
Windt
E L
EL
Grauel
A
A
Lukowsky
K
K
Tausendfreund
D001803:Blood Transfusion; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D012016:Reference Values
D005353:Fibronectins
Fibronektinkonzentrationen im Plasma von Neugeborenen und deren Müttern sowie verschiedenen Plasmaprärationen.