title: [Clinical study of HCFU and radiation therapy in head and neck cancer].
abstract: We have investigated the usefulness of combination therapy of HCFU with radiation by means of a multicenter trial from 1981 to 1984. One hundred fifty-three cases were registered and 120 of them were evaluable. The overall response rate was 72.5% with 55 complete responses and 32 partial responses. Adverse effects were found in 34.8% of patients. This combination therapy of HCFU with radiation was therefore concluded to be useful for multidisciplinary treatment of head and neck cancer.
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D006801:Humans; D008297:Male; D011879:Radiotherapy Dosage
chemical_list: D000970:Antineoplastic Agents; C017367:carmofur; D005472:Fluorouracil