[Effectiveness of various programs of immunocorrective therapy in chronic infectious-inflammatory diseases].
An immunological study of patients with chronic pneumonia, osteomyelitis, pyoderma and candidosis showed various changes in cellular immunity values within each nosological group of examined patients. The efficacy of levamisole therapy was higher in the group of patients where an increase in the number of E-rosette forming cells and NBT-test values by more than 10% was noted in vitro in the presence of 10 micrograms/ml of levamisole as opposed to patients with a less increase in these values or their decrease. Nonspecific immunotherapy (levamisole, prodigiosan) following specific immunotherapy (staphylococcal anatoxins and antiphagin or autovaccines) proved to be more effective in the treatment of patients with chronic infectious inflammatory diseases than the reverse sequence of immunotherapy courses.
D000276:Adjuvants, Immunologic; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002177:Candidiasis / Q000276:immunology / Q000628:therapy*; D002908:Chronic Disease; D005500:Follow-Up Studies; D006801:Humans; D007108:Immune Tolerance; D007153:Immunologic Deficiency Syndromes / Q000628:therapy*; D007167:Immunotherapy / Q000379:methods*; D066298:In Vitro Techniques; D007978:Levamisole / Q000008:administration & dosage; D010019:Osteomyelitis / Q000276:immunology / Q000628:therapy*; D011014:Pneumonia / Q000276:immunology / Q000628:therapy*; D011354:Prodigiozan / Q000008:administration & dosage; D011711:Pyoderma / Q000276:immunology / Q000628:therapy*; D013203:Staphylococcal Infections / Q000276:immunology / Q000628:therapy*; D013208:Staphylococcal Toxoid / Q000008:administration & dosage; D013209:Staphylococcal Vaccines / Q000008:administration & dosage
D000276:Adjuvants, Immunologic; D000900:Anti-Bacterial Agents; D013208:Staphylococcal Toxoid; D013209:Staphylococcal Vaccines; D007978:Levamisole; D011354:Prodigiozan
Effektivnost' razlichnykh skhem immunokorrigiruiushchei terapii khronicheskikh infektsionno-vospalitel'nykh zabolevaniĭ.