title: Total body fluid volume determination based on urea kinetics in hemofiltration as an index of basal body weight in uremic patients.
abstract: Assuming that urea is distributed uniformly within the total body water, urea-space or total body fluid volume was determined in six uremic patients based on urea kinetics in hemofiltration. The total body fluid volume before hemofiltration was 36.0 +/- 3.6 L (61.8 +/- 2.6% BW) and after hemofiltration 32.5 +/- 3.4 L (59.3 +/- 2.8% BW), suggesting that the total body fluid volume was nearly normalized by hemofiltration. It is concluded that urea-space, easily measurable based on urea kinetics during hemofiltration, is useful in evaluating the fluid balance in patients undergoing artificial kidney therapy.
mesh_terms: D001769:Blood; D001834:Body Water / Q000032:analysis*; D001835:Body Weight; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D014462:Ultrafiltration; D014508:Urea / Q000378:metabolism*; D014511:Uremia / Q000628:therapy*
chemical_list: D014508:Urea