Second primary carcinomas in patients with squamous cell carcinoma of the maxillary sinus.
Three hundred fifty-one patients with squamous cell carcinoma of the maxillary sinus received radiation therapy between 1953 and 1984. Nine subsequently developed cancers in other organs than the maxillary sinus, and five squamous cell carcinomas occurred in the second maxillary sinus. Analysis by the person-year approach suggested a remarkably increased risk of 67 times for second sinus cancer and no additional increased risk of cancers to other organs, such as the upper aerodigestive tract.
D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000532:radiotherapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D009378:Neoplasms, Multiple Primary; D010255:Paranasal Sinus Neoplasms / Q000473:pathology*; D012306:Risk; D013223:Statistics as Topic