[Interaction of alpha-tocopherol with free fatty acids. Spatial organization of the complex].
Stereoconfiguration of alpha-tocopherol-linoleic acid complex was studied using high resolution IH-NMR-spectroscopy. The addition of a fatty acid (linoleate) to alpha-tocopherol solution in CDCl3 resulted in the broadening of IH-NMR lines for OH- and phe-CH3-alpha-tocopherol groups. No changes in chemical shift values of IH-NMR lines for linoleic acid were observed after the addition of alpha-tocopherol to linoleic acid solution in CDCl3. It is concluded that in the complexes formed linoleic acid is located in the phenolic ring plane of alpha-tocopherol. The conclusion is supported by the data obtained on molecular models.
D005230:Fatty Acids, Nonesterified; D066298:In Vitro Techniques; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D014810:Vitamin E
D005230:Fatty Acids, Nonesterified; D046911:Macromolecular Substances; D014810:Vitamin E
Vzaimodeĭstvie alpha-tokoferola so svobodnymi zhirnymi kislotami. Prostranstvennaia organizatsiia kompleksa.