Hydroxypropyl-beta-cyclodextrin derivatives: influence of average degree of substitution on complexing ability and surface activity.
The average degree of substitution of mixtures of hydroxypropyl-beta-cyclodextrin derivatives has a large influence on the complexing abilities and physiochemical properties of the derivatives. A low degree of substitution is preferable, since these derivatives show the best complexing properties and, at the same time, low surface activities.
D002626:Chemistry, Pharmaceutical; D002851:Chromatography, High Pressure Liquid; D003505:Cyclodextrins / Q000032:analysis*; D003912:Dextrins / Q000032:analysis*; D013213:Starch / Q000032:analysis*; D013499:Surface Properties
D003505:Cyclodextrins; D003912:Dextrins; D013213:Starch