[Effect of thymectomy on the endocrine function of the adrenal cortex and testes in rats].
The paper is concerned with a study of endocrine function of the adrenal cortex and testes of rats after thymectomy using a radioimmunoassay. Postnatal thymectomy resulted after 3 months in a decrease in the level of corticosterone in the blood, the level of testosterone did not change as compared to that in animals after false operation. Thymectomized rats were characterized by a stronger sensitivity of the adrenals and gonads to physical exercise of moderate intensity which was expressed in a more significant elevation of the corticosterone level in the blood and a decrease in the testosterone level. A decrease in the Na+ concentration and an increase in the K+ content in erythrocytes and blood plasma were revealed in the thymectomized rats 3 and 6 mos after operation. A deficit of the thymus hormone influenced endocrine function of the adrenals and testes.
D000302:Adrenal Cortex / Q000378:metabolism*; D000818:Animals; D003345:Corticosterone / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D008297:Male; D011188:Potassium / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains; D012964:Sodium / Q000097:blood; D013737:Testis / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism; D013934:Thymectomy; D013951:Thymus Hormones / Q000172:deficiency / Q000502:physiology
D013951:Thymus Hormones; D013739:Testosterone; D012964:Sodium; D011188:Potassium; D003345:Corticosterone
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