Hyaluronic acid in rabbit pericardial fluid and its production by pericardium.
High-Mr (greater than 2 X 10(6)) hyaluronic acid (about 82 micrograms/ml) was found for the first time in rabbit pericardial fluid. Biosynthetic experiments with minced pericardium from rabbit showed that the high-Mr hyaluronic acid in the pericardial fluid was actively synthesized by the pericardium from [3H]glucosamine.
D000818:Animals; D001826:Body Fluids / Q000032:analysis; D002850:Chromatography, Gel; D005944:Glucosamine / Q000378:metabolism; D006025:Glycosaminoglycans / Q000032:analysis; D006820:Hyaluronic Acid / Q000032:analysis* / Q000096:biosynthesis; D010496:Pericardium / Q000032:analysis* / Q000378:metabolism; D011817:Rabbits; D014316:Tritium
D006025:Glycosaminoglycans; D014316:Tritium; D006820:Hyaluronic Acid; D005944:Glucosamine