Effect of glucose and other hexoses on efferent discharges of brown adipose tissue nerves.
The activity of sympathetic nerves innervating interscapular brown adipose tissue of the rat was recorded. Intravenous administrations of glucose (100-300 mg/kg) enhanced the nerve activity. However, mannose, fructose, or galactose (300 mg/kg) showed no effect, suggesting the response is related to diet-induced thermogenesis in the brown adipose tissue.
D002001:Adipose Tissue, Brown / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001833:Body Temperature Regulation; D004032:Diet; D004305:Dose-Response Relationship, Drug; D004525:Efferent Pathways / Q000187:drug effects / Q000502:physiology; D004594:Electrophysiology; D005947:Glucose / Q000494:pharmacology*; D006601:Hexoses / Q000494:pharmacology*; D008297:Male; D051381:Rats; D013564:Sympathetic Nervous System / Q000187:drug effects* / Q000502:physiology
D001786:Blood Glucose; D006601:Hexoses; D005947:Glucose