Bilateral Sertoli-Leydig cell tumor with heterologous elements: report of an unusual case and review of the literature.
A case of bilateral ovarian Sertoli-Leydig cell tumor with heterologous elements is reported in an 18-yr-old girl with marked virilization. Panhysterectomy was performed, yet the tumor recurred shortly after the intervention. The microscopic picture was one of intermediate to poor differentiation. Despite chemotherapy, the postoperative course was rapidly malignant, and the patient died 4 wk later.
D000038:Abscess / Q000209:etiology; D000293:Adolescent; D004312:Douglas' Pouch; D005260:Female; D006801:Humans; D007984:Leydig Cell Tumor / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology; D012707:Sertoli Cell Tumor / Q000473:pathology* / Q000601:surgery; D014770:Virilism / Q000209:etiology