Surface modification of soft contact lenses: silanization, wettability and lysozyme adsorption studies.
The surface reactions of poly(2-hydroxyethylmethacrylate) (PHEMA) and the copolymer poly(HEMA-methacrylic acid) (PHEMA/MAA) with methyltrimethoxysilane, ethyltrimethoxysilane and phenyltrimethoxysilane have been characterized by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. A model compound, hydroxyethyl isobutyrate was synthesized and subsequently reacted with phenyltrimethoxysilane. Its FTIR spectrum was compared with the ATR-FTIR spectra mentioned above. Protein adsorption experiments showed that silanized PHEMA/MAA soft contact lenses adsorbed less lysozyme than the untreated lenses.
D000327:Adsorption; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003263:Contact Lenses, Hydrophilic; D008689:Methacrylates; D009113:Muramidase / Q000032:analysis*; D011102:Polyhydroxyethyl Methacrylate; D012965:Sodium Chloride; D013499:Surface Properties
D008689:Methacrylates; D011102:Polyhydroxyethyl Methacrylate; D012965:Sodium Chloride; C005044:hydroxyethyl methacrylate; D009113:Muramidase