title: Influence of Anisotes trisulcus and Crepis rueppellii extracts on sites of bile formation in the rat.
abstract: Anisotes trisulcus and Crepis rueppellii, two medicinal plants from Yemen, have been investigated for their hepatobiliary properties. A study of their choleretic effect and of sites of bile formation was carried out in the rat, by evaluation of bile flow, bile acids output and 14C-erythritol clearance. The data suggest that both extracts of these plants induce hypercholeresis, but Anisotes would stimulate the bile acid-dependent fraction and Crepis the bile acid-independent fraction.
mesh_terms: D000818:Animals; D001646:Bile / Q000187:drug effects* / Q000378:metabolism; D001647:Bile Acids and Salts / Q000096:biosynthesis; D004896:Erythritol / Q000378:metabolism; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001647:Bile Acids and Salts; D010936:Plant Extracts; D004896:Erythritol