Bronze baby syndrome, biliary hypoplasia, incomplete Beckwith-Wiedemann syndrome and partial trisomy 11.
A premature infant with duplication of material from chromosome 11 and some features of the Beckwith-Wiedemann syndrome developed the bronze baby syndrome when exposed to phototherapy. He subsequently developed hepatocellular dysfunction and died aged 5 weeks. Post mortem examination revealed striking hypoplasia of intralobular bile ducts but little inflammatory change or necrosis in the liver.
D001506:Beckwith-Wiedemann Syndrome / Q000150:complications*; D001653:Bile Ducts, Intrahepatic / Q000002:abnormalities*; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases; D008297:Male; D010789:Phototherapy / Q000009:adverse effects*; D013577:Syndrome; D014314:Trisomy