Steroid-induced regression of primary malignant lymphoma of the brain.
A case of primary malignant lymphoma involving the splenium of the corpus callosum is reported in a 54-year-old woman presenting with symptoms of increased intracranial pressure. In view of the prominent cerebral edema associated with the intracranial lymphoma, dexamethasone was initiated at a daily dosage of 8 mg by intravenous administration. Computed tomography scans obtained 10 days after admission revealed dramatic regression of the lesion which corresponded with clinical remission. Steroid-induced regression of primary malignant lymphoma of the brain as evidenced by computed tomography is reviewed in the literature, and the role of corticosteroids is discussed.
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D003907:Dexamethasone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D011859:Radiography
D003907:Dexamethasone; D011239:Prednisolone