Long-standing pain relief of adiposis dolorosa (Dercum's disease) after intravenous infusion of lidocaine.
A 60-year-old woman with adiposis dolorosa for 20 years was treated with repeated intravenous infusions of lidocaine. Partial relief of pain in the legs was obtained after 1.3 gm. A dose of 5.2 gm lidocaine given for 4 days was needed for complete pain relief. The effect lasted for 3 weeks, and then the pain gradually returned. The patient has now been given two additional treatments with complete pain relief for 2 months. The mechanism of the effect remains unknown.
D000274:Adiposis Dolorosa / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008012:Lidocaine / Q000008:administration & dosage*; D008875:Middle Aged; D010148:Intractable Pain / Q000188:drug therapy*
D008012:Lidocaine