Ocular involvement in congenital leukemia.
Congenital leukemia, a rare disease with distinct features, was diagnosed in a 5-week-old girl. The infant was tachypneic and tachycardic, with intercostal retractions, distended abdomen, and multiple hematomas. Despite aggressive treatment, the child died. Histologic examination of tissue obtained at autopsy disclosed leukemic infiltrates in the ocular muscles, conjunctiva, uveal tract, and optic nerve.
D000869:Anterior Eye Segment / Q000473:pathology; D002830:Choroid Neoplasms / Q000473:pathology; D003230:Conjunctival Neoplasms / Q000473:pathology; D003390:Cranial Nerve Neoplasms / Q000473:pathology; D005134:Eye Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000151:congenital* / Q000473:pathology; D009801:Oculomotor Muscles / Q000473:pathology; D009901:Optic Nerve Diseases / Q000473:pathology