Subcutaneous heparin and postoperative wound hematomas. A prospective, double-blind, randomized study.
A prospective, double-blind, controlled study was conducted to assess the incidence of postoperative wound hematomas associated with low-dose subcutaneous heparin therapy among patients undergoing surgery for a single inguinal hernia. The groups were well matched. The results indicate that low-dose heparin therapy is associated with more wound hematomas. Complications of low-dose heparin therapy and new ways to avoid these complications are discussed. The indications for the prophylactic administration of low-dose heparin therapy need careful assessment.
D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006406:Hematoma / Q000139:chemically induced*; D006454:Hemoglobins / Q000378:metabolism; D006493:Heparin / Q000008:administration & dosage / Q000009:adverse effects*; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000139:chemically induced*; D011446:Prospective Studies; D011897:Random Allocation; D013924:Thrombophlebitis / Q000517:prevention & control
D006454:Hemoglobins; D006493:Heparin