title: Nocturnal sleep in infants with congenital cerebral malformation.
abstract: Sleep EEG patterns in 17 infants with cerebral malformations (4 months to 4 years of age) were studied throughout nocturnal sleep and the following results were obtained. Seven cases evidenced normal sleep/wakefulness EEG patterns that could be classified into 6 stages. Ten cases showed abnormal sleep EEG patterns as follows: absence of sleep spindles (n = 7) which included cases of absence of EEG patterns characteristic of wakefulness, NREM sleep and REM sleep (n = 5), no characteristic EEG patterns of stages 1-4 (n = 1) and stages W, 1, 2 and REM (n = 1) and the remaining cases with absence of spindles (n = 1), and spindles with an extremely low incidence (n = 2). Short sleep and long awaking times, and no delta rhythmicity during the night, were noted in 5 out of 17 subjects. A significant decrease of DQ was found in subjects with indistinguishable stages including stages W, 1, 2 and REM, as compared with those patients whose stages were all distinguishable.
mesh_terms: D061085:Agenesis of Corpus Callosum; D001139:Arnold-Chiari Malformation / Q000503:physiopathology; D001921:Brain / Q000002:abnormalities*; D002540:Cerebral Cortex / Q000002:abnormalities; D002675:Child, Preschool; D004569:Electroencephalography; D005260:Female; D006801:Humans; D006832:Hydranencephaly / Q000503:physiopathology; D007223:Infant; D008297:Male; D008831:Microcephaly / Q000503:physiopathology; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology