Reactions to Quaternium 15, Bronopol and Germall 115 in a standard series.
The incidence of positive patch test reactions to Quaternium 15 has increased by a factor of 3 within a relatively stable population over 2 years, while the incidence of reactions to Bronopol and Germall 115 has remained static. The problem of interpreting an apparent positive reaction to a formaldehyde-releasing preservative in a formaldehyde-sensitive patient is discussed.
D003358:Cosmetics; D005260:Female; D005557:Formaldehyde / Q000009:adverse effects; D006801:Humans; D008297:Male; D008709:Methenamine / Q000009:adverse effects / Q000031:analogs & derivatives*; D010328:Patch Tests; D010592:Pharmaceutic Aids / Q000009:adverse effects*; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D011409:Propylene Glycols / Q000009:adverse effects*; D012882:Skin Tests; D014508:Urea / Q000009:adverse effects / Q000031:analogs & derivatives*
D003358:Cosmetics; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D011409:Propylene Glycols; D005557:Formaldehyde; C006827:bronopol; D014508:Urea; C018375:quaternium-15; D008709:Methenamine; C006048:imidazolidinyl urea