title: Serum cholesterol and cancer--a retrospective case-control study.
abstract: The time relationship between low serum cholesterol and the subsequent development of malignant neoplasms was examined in a case-control study of 100 cases of cancer death and 393 controls. The serum cholesterol levels were followed by repeated blood analysis over a 16-year period. An association between low serum cholesterol and cancer death was found particularly for malignant neoplasms of the large intestine and rectum. This relationship diminished 7-16 years prior to death suggesting that the low serum cholesterol levels were an effect of the cancer in an early stage and not vice versa.
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood / Q000401:mortality; D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood* / Q000401:mortality; D012189:Retrospective Studies; D012306:Risk; D013548:Sweden; D013997:Time Factors; D014505:Urban Population
chemical_list: D002784:Cholesterol