[Multimethod for the determination of residues of chemotherapeutic drugs, antiparasitic agents and growth promotors in foodstuffs of animal origin. 1. General procedure and determination of sulfonamides].
Applying this Multi-Method, it is possible to isolate more than 60 chemotherapeutics, antiparasitics and growth promoters in one procedure from eggs, milk and meat. Residues are detected by different chromatographic systems (HPLC with UV-Detection, Capillary-GC with an ECD). Depending on substance and foodstuff, the following detection limits can be achieved: (Table: see text). The observance of the legal tolerance level of 0.001 mg/kg Chloramphenicol (valid only for milk and eggs in the Fed. Rep. Germany) can be supervised. Residues of most Sulfonamides can be determined to adequately, check the proposed tolerance level of 0.1 mg/kg. The first part presents the procedure (applicable for all substances) and contains the summary of the chromatographic parameters for the detection of all substances and the detailed parameters for Sulfonamides. The conformation of residues of Sulfonamides is discussed carefully.
D000818:Animals; D000890:Anti-Infective Agents / Q000032:analysis; D002498:Centrifugation; D002701:Chloramphenicol / Q000032:analysis; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D004356:Drug Storage; D005504:Food Analysis; D006133:Growth Substances / Q000032:analysis*; D007202:Indicators and Reagents; D004364:Pharmaceutical Preparations / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet; D013449:Sulfonamides / Q000032:analysis*
D000890:Anti-Infective Agents; D006133:Growth Substances; D007202:Indicators and Reagents; D004364:Pharmaceutical Preparations; D013449:Sulfonamides; D002701:Chloramphenicol
Multimethode zur Bestimmung der Rückstände von Chemotherapeutica, Antiparasitica und Wachstumsförderern in Lebensmitteln tierischer Herkunft. 1. Mitteilung: Allgemeine Arbeitsvorschrift und Bestimmung von Sulfonamiden.