title: A quantitative immunohistochemical study on the pituitary LH gonadotrophs in the female Afghan pika after copulation.
abstract: The female Afghan pika is known as a species of copulatory ovulators exhibiting persistent estrus unless copulatory stimuli are employed. The plasma LH concentration rose quickly after copulation, peaked at 6 h and descended thereafter until 12 h. Before copulation (estrus), immunoreactive LH-containing cells of the pituitary in this species were filled with numerous large electron dense secretory granules, but the Golgi apparatus and the granulated endoplasmic reticulum were not well developed. One hour later the stainability of the cells was faint, their secretory granules were malls in size and in number, and were of low electron density. These alterations were the most predominant at 12 h after copulation. No exocytotic extrusion of secretory granules was observed throughout the experiment.
mesh_terms: D000818:Animals; D003307:Copulation; D005260:Female; D007793:Lagomorpha; D007986:Luteinizing Hormone / Q000032:analysis* / Q000097:blood; D008854:Microscopy, Electron; D010052:Ovariectomy; D010060:Ovulation; D010902:Pituitary Gland / Q000032:analysis* / Q000166:cytology / Q000648:ultrastructure; D013997:Time Factors
chemical_list: D007986:Luteinizing Hormone