[Comparative study of the lymphocyte surface receptors isolated from the blood and tissue of malignant tumors].
Comparative investigation of subpopulations and functional properties of lymphocytes isolated from the tumour tissue (TTL) as well as of lymphocytes of the peripheral blood (PBL) of 11 lung cancer patients and 18 breast cancer patients has shown that an increase in the quantity of theophylline-sensitive cells (suppressors and killers) is characteristic of TTL. After 20 hours of incubation of the mixture of the studied lymphocytes and sheep erythrocytes at 4 degrees C an increase in the number of E-RFC proved to be more intensive for TTL than for PBL. The result obtained may suggest the blocking of the superficial receptors of TTL to sheep erythrocytes.
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000276:immunology* / Q000532:radiotherapy; D006801:Humans; D008175:Lung Neoplasms / Q000276:immunology*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D008875:Middle Aged; D011971:Receptors, Immunologic / Q000187:drug effects / Q000276:immunology*; D012397:Rosette Formation; D013696:Temperature; D013806:Theophylline / Q000494:pharmacology; D013997:Time Factors
D011971:Receptors, Immunologic; D013806:Theophylline
Sravnitel'noe izuchenie poverkhnostnykh retseptorov limfotsitov, vydelennykh iz krovi i tkani zlokachestvennykh opukholeĭ.