Ultrastructural changes in mollicutes induced by the peptide antibiotic herbicolin A.
Electron microscopy of negatively stained mycoplasma, ureaplasma, and acholeplasma cells showed ultrastructural changes after 10 min of treatment of the organisms with the peptide antibiotic herbicolin A in concentrations ranging from 10 micrograms/ml for Mycoplasma capricolum to 600 micrograms/ml for Ureaplasma urealyticum. The morphological changes were shown to be reversible at low concentrations of the antibiotic but irreversible at high concentrations.
D000127:Acholeplasma / Q000187:drug effects* / Q000648:ultrastructure; D000128:Acholeplasma laidlawii / Q000187:drug effects / Q000648:ultrastructure; D008854:Microscopy, Electron; D009174:Mycoplasma / Q000187:drug effects* / Q000648:ultrastructure; D009842:Oligopeptides; D010455:Peptides / Q000494:pharmacology; D014509:Ureaplasma / Q000187:drug effects* / Q000648:ultrastructure
D009842:Oligopeptides; D010455:Peptides; C027099:herbicolin A