[Effect of naphthoquinones and tocopherols on the level of integral proteins in mitochondrial membranes and DNA levels in rat and rabbit tissue].
Naphthoquinones and tocopherols are studied for their effect on the state of integral proteins of the mitochondrial liver and myocardium membranes in the experiments on the male rats and rabbits. It is established that deficiency of vitamins K and E in the organism (naphthoquinones and tocopherols) is followed by a decrease in the content of integral proteins and by disturbances in correlation of their fractions. These changes in K, E-avitaminosis are accompanied by a decrease of the DNA content in the tissues. Realization of K and E vitamins on the level of structural biomembrane organization is supposed to be possible.
D000818:Animals; D004247:DNA / Q000032:analysis*; D008297:Male; D008565:Membrane Proteins / Q000032:analysis*; D008928:Mitochondria / Q000032:analysis*; D009285:Naphthoquinones / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D014018:Tissue Distribution; D014810:Vitamin E / Q000494:pharmacology*; D014811:Vitamin E Deficiency / Q000378:metabolism; D014813:Vitamin K Deficiency / Q000378:metabolism
D008565:Membrane Proteins; D009285:Naphthoquinones; D014810:Vitamin E; D004247:DNA
Vliianie naftokhinonov i tokoferolov na soderzhanie integral'nykh belkov v membranakh mitokhondriĭ i DNK v tkaniakh krys i krolikov.