title: [New method of treating Itsenko-Cushing disease by transvenous destruction of the adrenals].
abstract: A new method was developed for therapy of Icenko-Cushing's disease using transcatheter transvenous destruction of the adrenals (TTDA) to replace commonly used adrenalectomy. TTDA was performed by means of venous extravasation of a radiopaque agent (76% verografin solution) and its deposition in the organ parenchyma. TTDA was performed in 57 patients with Icenko-Cushing's disease using 3 tactical approaches including roentgenovascular intervention: bilateral TTDA, unilateral TTDA combined with unilateral adrenalectomy and unilateral TTDA combined with chloditan. TTDA is an effective method of invasive suppression of function of the cortex of the endocrine glands. TTDA superiority over surgical methods of therapy Icenko-Cushing's disease is that an effect of adrenalectomy is achieved without a risk of surgical intervention and narcosis.
mesh_terms: D015065:17-Hydroxycorticosteroids / Q000652:urine; D000315:Adrenalectomy; D000328:Adult; D002404:Catheterization; D003131:Combined Modality Therapy; D003480:Cushing Syndrome / Q000628:therapy*; D003973:Diatrizoate / Q000031:analogs & derivatives*; D003974:Diatrizoate Meglumine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008939:Mitotane / Q000627:therapeutic use
chemical_list: D015065:17-Hydroxycorticosteroids; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D008939:Mitotane
vernacular_title: Novyĭ metod lecheniia bolezni Itsenko-Kushinga chrezvenoznoĭ destruktsieĭ nadpochechnikov.