Methylglyoxal bis(butylamidinohydrazone), a new inhibitor of polyamine biosynthesis that simultaneously inhibits ornithine decarboxylase, adenosylmethionine decarboxylase and spermidine synthase.
D012437:Adenosylmethionine Decarboxylase / Q000037:antagonists & inhibitors*; D000818:Animals; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors*; D007700:Kinetics; D008935:Mitoguazone / Q000031:analogs & derivatives* / Q000494:pharmacology; D065108:Ornithine Decarboxylase Inhibitors; D051381:Rats; D011436:Spermidine Synthase / Q000037:antagonists & inhibitors*; D014166:Transferases / Q000037:antagonists & inhibitors*
D065108:Ornithine Decarboxylase Inhibitors; C047167:methylglyoxal bis(butylamidinohydrazone); D014166:Transferases; D011436:Spermidine Synthase; D002262:Carboxy-Lyases; D012437:Adenosylmethionine Decarboxylase; D008935:Mitoguazone