title: Correlation of double-contrast high-density barium enema, colonoscopy, and histology in children with special attention to disparities.
abstract: Colonoscopic and double-contrast high-density barium enema (DCBE) findings were correlated in 68 patients (39 boys and 29 girls) aged 6 months to 18 years (mean 11.6 years) evaluated over a 24-month period. There was excellent correlation in 53 patients (78.0%) and good correlation in another 3 (4.4%) who had identical diagnoses and only slightly differing extent of disease reported. In 2 of these, DCBE showed more extensive disease, confirmed histologically in 1. Distal colitis seen on colonoscopy as reddening and neovascularity was missed on DCBE in 6 patients. Colonoscopy and DCBE failed to show a polyp in 1 patient each. One patient who had a normal DCBE and colonoscopy demonstrated a histological abnormality, and 1 patient with an abnormality on histology and DCBE was normal on colonoscopy. A disparity resulted from the time between procedures in 1 patient and observer error in another. This high correlation is far better than any previously reported in children, supporting the use of high-density barium sulfate and double-contrast barium enemas in pediatric patients.
mesh_terms: D000293:Adolescent; D001466:Barium Sulfate; D002648:Child; D002675:Child, Preschool; D003092:Colitis / Q000175:diagnosis / Q000000981:diagnostic imaging; D003106:Colon / Q000473:pathology*; D003108:Colonic Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging; D003113:Colonoscopy; D004733:Enema; D004802:Eosinophilia / Q000175:diagnosis / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007223:Infant; D007417:Intestinal Polyps / Q000175:diagnosis / Q000000981:diagnostic imaging; D008297:Male; D011859:Radiography
chemical_list: D001466:Barium Sulfate