[Intracytoplasmic desmosome in squamous cancer cells of the lung in man].
Ultrastructure of intracytoplasmic (cytoplasmic) desmosomes in the squamous cancer cells of the human lung was studied by electron microscopy. In 17 cases of non-keratosic squamous cell carcinoma of the lung, intracytoplasmic (cytoplasmic) desmosomes were found in 4. In contrast to what previous investigators had proposed that the intracytoplasmic desmosomes are formed by cell fusion with the membrane being deep in the cell and cell digestion under the diffusion of hydrolytic enzymes, our result indicates that the intracytoplasmic desmosomes might be a structure formed by cell intima system itself during cell division. The structure suggests that the desmosomes originate from the cell intima system.
D002294:Carcinoma, Squamous Cell / Q000648:ultrastructure*; D003593:Cytoplasm / Q000648:ultrastructure*; D003896:Desmosomes / Q000648:ultrastructure*; D006801:Humans; D008175:Lung Neoplasms / Q000648:ultrastructure*