title: Polymorphism of plasminogen in healthy individuals and patients with cerebral infarction.
abstract: Phenotyping of plasma plasminogen (PLG) was carried out by the method of agarose gel isoelectric focusing followed by immunofixation or immunoblotting. The allele frequencies calculated from healthy Japanese individuals (n = 795) were as follows: PLG*1 = 0.9440, PLG*2 = 0.0189, PLG*A = 0.0076, PLG*A2 = 0.0006, PLG*B = 0.0138, PLG*B2 = 0.0013, and PLG*C = 0.0138. The PLG phenotype distribution in a group of patients with cerebral infarction (n = 125) was also studied. The allele frequencies were PLG*1 = 0.960, PLG*2 = 0.016, PLG*A = 0.012, and PLG*B = 0.012. No statistically significant association was found between PLG types and cerebral infarction.
mesh_terms: D000483:Alleles; D002544:Cerebral Infarction / Q000097:blood* / Q000235:genetics; D005787:Gene Frequency; D006801:Humans; D010641:Phenotype; D010958:Plasminogen / Q000235:genetics*; D011110:Polymorphism, Genetic; D012016:Reference Values
chemical_list: D010958:Plasminogen