[Study of coagulum pyelolithotomy].
Coagulum pyelolithotomy was carried out on 20 patients from January, 1980 to April 1984. Nephrolithotomy was jointly carried out on 4 of them, but residual stones were observed in 4 cases (20%). No side effect such as hepatitis was observed in any cases. While inferring the cause of residue, experimental study was made on tension, coagulation time and mixing method in respect to coagulum formation. In the experiment on tension, no significant difference was observed when thrombin concentration was changed, but when calcium was added, tension increased 4 fold. As thrombin concentration rose, so shortened the coagulation time. It was inferred that a better coagulum is made available if fibrinogen and thrombin are mixed outside the kidney.
D000328:Adult; D000368:Aged; D005260:Female; D005340:Fibrinogen / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007669:Kidney Calculi / Q000601:surgery* / Q000628:therapy; D007682:Kidney Pelvis / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D013917:Thrombin / Q000008:administration & dosage / Q000627:therapeutic use*
D005340:Fibrinogen; D013917:Thrombin