title: [Effect of nutrition on lysosomal function during physical loading].
abstract: Changes of cardiac, sceletal and hepatic lysosomes effected by three different variants of balanced isocaloric diets: 1--basic, 2--protein-lipid and 3--carbohydrate, with ratios of proteins, lipids and carbohydrates in mass 1.0:0.35:2.6; 1.0:0.48:0.67; and 1.0:1.3:10.9, respectively, were studied. Activities of enzymes participating in degradation of carbohydrates (beta-glucosidase, beta-N-acetyl-glucosaminidase) were more increased in the animals fed with the carbohydrate diet. Activation of proteolytic enzymes (cathepsin D) was observed in tissues of rats taking the protein-lipid food. As a rule physical exercise exerts lysosomal enzymes activation and their membrane labilization in rats maintained on the basic diet. Reversial reactions of lysosomes to physical exercise is observed in animals receiving the carbohydrate diet for along time that is expressed in increasing the total activity of lysosomal hydrolases and stabilizing the lysosomal membranes. On the contrary, maintaining the animals on the protein-lipid diet is followed by a more pronounced activation of the lysosomal apparatus of tissues as compared to the basic diet.
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D004032:Diet; D008099:Liver / Q000201:enzymology; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D009132:Muscles / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D012146:Rest
vernacular_title: Vliianie pitaniia na sostoianie lizosom pri fizicheskoĭ nagruzke.