Antigenic probes locate the myosin subfragment 1 interaction site on the N-terminal part of actin.
The interaction of two different anti-actin antibody populations with the myosin subfragment 1-F-actin rigor complex has been studied. In contrast with the 1-7 sequence, the 18-28 sequence appears to be strongly implicated in the contact area of the myosin head on the actin polypeptide chain.
D000199:Actins / Q000378:metabolism*; D000595:Amino Acid Sequence; D000818:Animals; D000937:Antigen-Antibody Reactions; D001665:Binding Sites; D007120:Immunochemistry; D015879:Myosin Subfragments; D009218:Myosins / Q000276:immunology / Q000378:metabolism*; D010446:Peptide Fragments / Q000276:immunology / Q000378:metabolism*; D011817:Rabbits
D000199:Actins; D015879:Myosin Subfragments; D010446:Peptide Fragments; D009218:Myosins