title: Malignant leiomyomatosis peritonealis disseminata.
abstract: The first known case of malignant change occurring in leiomyomatosis peritonealis disseminata is reported. Six months after leiomyomatosis peritonealis disseminata was found at cesarean section, the patient experienced rapid growth of the pelvic tumor and diffuse bony metastases. The most cellular areas of the pelvic lesions and the bony metastases were very similar histologically. No other primary site was identified. Despite combination chemotherapy and hormonal manipulations, the patient experienced a rapidly declining course and died within two years.
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D005270:Femur Head / Q000473:pathology; D006801:Humans; D007889:Leiomyoma / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D009852:Omentum / Q000473:pathology; D014594:Uterine Neoplasms / Q000473:pathology* / Q000628:therapy; D014599:Uterus / Q000473:pathology*