title: Cytologic diagnosis of orbital and periorbital palpable tumors using fine-needle sampling without aspiration.
abstract: Sixty-two cases of orbital and periorbital palpable neoplasms were analyzed cytologically. The material was obtained by our technique of simply introducing a fine injection needle in the tumor mass without aspiration. Fifty-six of these tumors had a subsequent histologic diagnosis by surgical procedure or biopsy. Forty-nine of the 56 cytologic diagnoses (87%) were concordant with the histologic findings with regard to malignancy and its variety. In three other cases the diagnosis of malignancy was only achieved by surgical procedure or biopsy (5%). In two cases, there were false-malignant results (4%), one corresponding to a meningioma and the other related to a reactive lymphoid hyperplasia. There was one false-benign (2%) result in a case of non-Hodgkin's lymphoma. In one patient, the cytologic material was insufficient for diagnosis (2%). In six other cases, the initial cytologic examination was ultimately confirmed either by biochemical studies or by biopsies of nodal metastases. No orbital hemorrhage was observed after fine-needle sampling. This outpatient technique is highly accurate and permits diagnosis in a few minutes.
mesh_terms: D001707:Biopsy, Needle / Q000379:methods; D003937:Diagnosis, Differential; D005134:Eye Neoplasms / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000473:pathology*