On stages of postdenervational disturbances in functioning of the human salivary parotid gland (a concise report).
The author presents an original classification of the muscarinic cholinoreceptor subpopulations in the human salivary parotid gland in normal condition or following parasympathetic denervation. The criteria characterizing each stage of the postdenervational syndrome and the general scheme of their occurrence and restoration both reflect the stages of evolutionary transformations in cholinergic receptors. Assessment of salivation rate and volume, observed as the effect of vegetotropic agents, and of electrolyte contents in saliva provide the above scheme of 3 stages of the postdenervational syndrome.
D001285:Atropine / Q000502:physiology; D004351:Drug Resistance; D006801:Humans; D010277:Parasympathomimetics / Q000494:pharmacology; D010305:Parotid Diseases / Q000378:metabolism / Q000503:physiopathology*; D010306:Parotid Gland / Q000378:metabolism / Q000503:physiopathology*; D011976:Receptors, Muscarinic / Q000145:classification / Q000502:physiology; D014947:Wounds and Injuries / Q000150:complications*
D010277:Parasympathomimetics; D011976:Receptors, Muscarinic; D001285:Atropine