title: [Hand-Schüller-Christian syndrome arising in the mandible. A case report].
abstract: The history of Letterer-Siwe, Hand-Schüller-Christian disease, and eosinophilic granuloma of the bone, and the evolution of the concept of grouping them together under the common term of histiocytosis X are presented. The characteristics of the disease, with particular emphasis on oral manifestations, are reviewed. The therapy for the disease is briefly outlined. One case of Hand-Schüller-Christian syndrome is presented. The discussion is focused on the problem of chemotherapy in disseminated forms.
mesh_terms: D000328:Adult; D001623:Betamethasone / Q000031:analogs & derivatives / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008727:Methotrexate / Q000627:therapeutic use; D011859:Radiography; D013997:Time Factors; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D014747:Vinblastine; C028994:betamethasone sodium phosphate; D001623:Betamethasone; D008727:Methotrexate
vernacular_title: Sindrome di Hand-Schüller-Christian a insorgenza mandibolare. Presentazione di un caso.