title: Histological changes in the vaginal connective tissue of patients with and without uterine prolapse.
abstract: The histological structure of the vaginal fascia was studied in two groups of patients: 10 consecutive women having a vaginal repair for uterine prolapse or descent and 10 consecutive women having an abdominal hysterectomy for fibroids. Abnormal histological changes were found in 7 out of 10 patients with uterine descent as compared to 2 out of 10 controls (P less than 0.05). This suggests a correlation between histological changes in vaginal connective tissue and pelvic laxity.
mesh_terms: D003094:Collagen; D005205:Fascia / Q000033:anatomy & histology* / Q000473:pathology; D005260:Female; D005347:Fibroblasts; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D014596:Uterine Prolapse / Q000473:pathology*; D014621:Vagina / Q000033:anatomy & histology* / Q000473:pathology
chemical_list: D003094:Collagen