title: Aneuploidy in Bowen's disease.
abstract: Distinct aneuploid clones of keratinocytes were detected in six cases of cutaneous Bowen's disease. As Bowen's disease is an accepted precursor of malignancy, aneuploidy may prove to be a useful indicator of the risk of invasive change in dermatoses questionably pre-malignant.
mesh_terms: D000782:Aneuploidy; D001913:Bowen's Disease / Q000032:analysis / Q000235:genetics* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000235:genetics*; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D011379:Prognosis; D012878:Skin Neoplasms / Q000032:analysis / Q000235:genetics* / Q000473:pathology
chemical_list: D004273:DNA, Neoplasm