Migraine.
Classic migraine appears to be due to a primary focal change in cerebral neuronal metabolism associated with a spreading reduction in cerebral blood flow. Abnormalities of platelets and certain vasoactive amines have been found but we are still a long way from understanding the pathogenesis of migraine.
D000588:Amines / Q000378:metabolism; D001792:Blood Platelets / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D002560:Cerebrovascular Circulation; D006801:Humans; D008881:Migraine Disorders / Q000209:etiology* / Q000503:physiopathology; D014666:Vasomotor System / Q000503:physiopathology
D000588:Amines