title: Three day oral course of Augmentin to treat chancroid.
abstract: Amoxycillin and clavulanic acid (Augmentin; Beecham Research Laboratories) was used to treat patients with bacteriologically proved chancroid in three different dose regimens. A single dose of Augmentin (amoxycillin 3 g, clavulanic acid 350 mg) was found to be ineffective. A similar dose repeated after 24 hours was equally ineffective, but a dose (amoxycillin 500 mg, clavulanic acid 250 mg) given every 8 hours for three days was found to be effective. The drug was well tolerated and no side effects were noted in any of the patients treated.
mesh_terms: D000284:Administration, Oral; D000658:Amoxicillin / Q000008:administration & dosage* / Q000627:therapeutic use; D019980:Amoxicillin-Potassium Clavulanate Combination; D002602:Chancroid / Q000188:drug therapy*; D002969:Clavulanic Acids / Q000008:administration & dosage* / Q000627:therapeutic use; D004334:Drug Administration Schedule; D004338:Drug Combinations / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male
chemical_list: D002969:Clavulanic Acids; D004338:Drug Combinations; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin