title: Simultaneous patency of ductus arteriosus and surgical shunt in pulmonary atresia with intact ventricular septum. A cause of acute myocardial failure?
abstract: Twenty-seven patients with pulmonary atresia and intact interventricular septum were treated with prostaglandin E1 infusion, followed by standard or modified Blalock-Taussig shunt. Three infants died. In all three there was anatomic and functional patency of the ductus arteriosus and the surgical systemic-pulmonary shunt. The unusual clinical course in these cases suggests that in the clinical management of patients with pulmonary atresia and intact interventricular septum after a shunt operation, particular attention must be paid to the problems associated with persistent ductal patency.
mesh_terms: D004374:Ductus Arteriosus, Patent / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities*; D008297:Male; D011183:Postoperative Complications / Q000209:etiology; D011458:Prostaglandins E / Q000627:therapeutic use; D011651:Pulmonary Artery / Q000601:surgery*; D013348:Subclavian Artery / Q000601:surgery*
chemical_list: D011458:Prostaglandins E