title: The minimal requirement of circulation for survival of undelayed and delayed flaps in rats.
abstract: In an attempt to clarify the delay phenomenon, the regional blood flow was measured in 10 undelayed flaps and 65 delayed flaps in rats by the clearance method with the electrolytically generated hydrogen. The ultimate purpose of this study was to establish the minimal requirement of blood flow for flap survival. The dye distance and the survival length were also measured. Blood flow in the flap increased with the delay period. Elongation of the survival length and the dye distance corresponded well to the circulatory enhancement. The present findings support the theory that delay improves blood circulation. The distance from the base to the 0.04-ml flow point was found to be highly correlated with survival length in the delayed groups as well as in the undelayed group. Based on the results, the minimal requirement of circulation for flap survival was assumed to be approximately 0.04 ml/min per gram of tissue whether or not the flap was delayed.
mesh_terms: D000818:Animals; D062109:Dermatologic Surgical Procedures; D004572:Electrolysis; D019793:Fluorescein; D005452:Fluoresceins; D006859:Hydrogen / Q000378:metabolism; D008297:Male; D008722:Methods; D051381:Rats; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply*; D013524:Surgical Flaps; D013997:Time Factors
chemical_list: D005452:Fluoresceins; D006859:Hydrogen; D019793:Fluorescein