[The potential antineoplastic acting constituents of Physalis alkekengi L. var franchetii Mast].
In a continuing search for potent antineoplastic compounds in indigenous plants, a water extract of Physalis alkekengi L. var. franchetii Mast. fruits was shown to have reproducible antineoplastic activity against Ehrlich ascites carcinoma in mice. Systematic fractionation of the extract led to the isolation of citric acid as the major active principle.
D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy; D002852:Chromatography, Ion Exchange; D002951:Citrates / Q000032:analysis; D019343:Citric Acid; D005260:Female; D008297:Male; D051379:Mice; D008811:Mice, Inbred DBA
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D002951:Citrates; D019343:Citric Acid
Untersuchungen über potentiell antineoplastisch wirksame Inhaltsstoffe von Physalis alkekengi L. var. franchetii Mast.