title: [Carcinogenic activity of some Soviet drug preparations].
abstract: After the long-term administration of doxilane-diolane, cresacin, antioxidant S-1 and fluorine varnish to mongrel albino rats and mice no difference in the level of spontaneous tumours both in the control and experimental groups of animals was observed. It is concluded that these drugs possess no carcinogenic activity.
mesh_terms: D000085:Acetates / Q000633:toxicity; D000818:Animals; D000975:Antioxidants / Q000633:toxicity; D002273:Carcinogens / Q000633:toxicity*; D002327:Cariostatic Agents / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations / Q000633:toxicity; D004983:Ethanolamines / Q000633:toxicity; D005260:Female; D005460:Fluorides, Topical / Q000633:toxicity; D008297:Male; D051379:Mice; D009374:Neoplasms, Experimental / Q000139:chemically induced*; D051381:Rats; D012821:Silanes / Q000633:toxicity; D013876:Thiophenes / Q000633:toxicity
chemical_list: D000085:Acetates; D000975:Antioxidants; D002273:Carcinogens; D002327:Cariostatic Agents; D004338:Drug Combinations; D004983:Ethanolamines; D005460:Fluorides, Topical; D012821:Silanes; D013876:Thiophenes; C041003:dimethyl-di-(N-phenylaminophenoxy)silane; C049483:3,4-dihydroxysulfolane; C047413:crezacin; C040655:ftorlak
vernacular_title: Izuchenie kantserogennoĭ aktivnosti u nekotorykh otechestvennykh lekarstvennykh preparatov.