Adverse reactions to the intravesical administration of doxorubicin hydrochloride: report of 6 cases.
We report 6 cases of adverse systemic reactions to the intravesical instillation of doxorubicin hydrochloride for the treatment of recurrent superficial transitional cell carcinoma of the bladder. Although local reactions to this drug are common they rarely are life-threatening. Significant systemic toxicity has not been reported.
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy*; D004317:Doxorubicin / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D007507:Therapeutic Irrigation / Q000379:methods; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
D004317:Doxorubicin