[Lipid metabolism in rat tissues after irradiation at doses causing interphase cell death].
Irradiation of animals with doses eliciting interphase death of 50-80% of cells activates lipogenesis and decreases the cholesterol content of cells. Cholesterol synthesis is activated after irradiation with doses causing death of 50% of cells: a further increase in radiation dose decreases the cholesterol synthesis. It is assumed that as membranes are destructed by radiation the adaptive lipogenesis activated to restore them.
D000818:Animals; D002470:Cell Survival / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D007399:Interphase / Q000528:radiation effects; D050356:Lipid Metabolism; D008055:Lipids / Q000528:radiation effects; D008099:Liver / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects*; D008214:Lymphocytes / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects*; D008297:Male; D011833:Radiation Injuries, Experimental / Q000378:metabolism* / Q000473:pathology; D011836:Radiation Tolerance; D051381:Rats; D011919:Rats, Inbred Strains
D008055:Lipids
Lipidnyĭ obmen v tkaniakh krys pri dozakh oblucheniia, vyzyvaiushchikh interfaznuiu gibel' kletok.