title: Time-resolved X-ray diffraction studies of the B in equilibrium D structural transition in the DNA double helix.
abstract: Because of the relation between topology and function, there has been much interest in the structural transitions of the various conformations of DNA polymers. The x-ray fiber diffraction analysis system at the Daresbury Synchrotron Radiation Source was used to study the reversible transition between the B and D forms of the synthetic DNA poly[d(A-T)].poly[d(A-T)]. The gradual progression of conformations between these two forms indicates that the DNA double helix does not undergo a change of handedness during this transition.
mesh_terms: D004247:DNA; D009690:Nucleic Acid Conformation; D011067:Poly dA-dT; D014961:X-Ray Diffraction
chemical_list: D011067:Poly dA-dT; D004247:DNA