Segregation analysis of brown oculocutaneous albinism.
The segregation of brown (type IV) oculocutaneous albinism was analyzed in 18 Nigerian families. Analysis using the POINTER program showed that this type of oculocutaneous albinism was inherited in an autosomal recessive pattern, with an estimated gene frequency of 0.025 +/- 0.007 in this population. The enzyme defect responsible for brown oculocutaneous albinism is unknown.
D000417:Albinism / Q000235:genetics*; D044383:Black People; D005123:Eye / Q000503:physiopathology; D005808:Genes, Recessive; D006801:Humans; D009549:Nigeria; D010375:Pedigree; D012867:Skin / Q000503:physiopathology