title: Binding of normal human mononuclear cells to blood vessels in rheumatoid arthritis synovial membrane.
abstract: We examined the binding of mononuclear cells to blood vessels in the rheumatoid arthritis synovial membrane. Two of 4 synovia that had lymphocyte-rich areas contained blood vessels adhesive for mononuclear cells. These reactive vessels showed striking similarities to high endothelial venules of the paracortical region of lymph node, where normal lymphocyte-endothelial cell adhesion and lymphocyte emigration into tissue occurs.
mesh_terms: D000818:Animals; D001172:Arthritis, Rheumatoid / Q000473:pathology*; D002448:Cell Adhesion; D004727:Endothelium / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D008198:Lymph Nodes / Q000473:pathology; D008214:Lymphocytes / Q000502:physiology*; D051381:Rats; D013154:Spleen / Q000166:cytology; D013583:Synovial Membrane / Q000098:blood supply*; D014699:Venules / Q000473:pathology