Use of interactive computer technology in open clinical trials. Study with trazodone in depressed patients.
This study reports the efficacy and safety of trazodone as an antidepressant drug in a national telematic multicenter outpatient open clinical trial. In less than 3 months, 1,700 patients completed a 1-month treatment and among them, 65% were considered as responders. The side effect profile of the drug included sedation, gastrointestinal discomfort and moderate hypotension. One case of trazodone-induced priapism is presented and briefly discussed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic / Q000379:methods*; D003201:Computers; D003866:Depressive Disorder / Q000188:drug therapy*; D004244:Dizziness / Q000139:chemically induced; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced; D011317:Priapism / Q000139:chemically induced; D012893:Sleep Wake Disorders / Q000139:chemically induced; D014196:Trazodone / Q000009:adverse effects / Q000627:therapeutic use*
D014196:Trazodone