Total serum IgE and specific IgE antibodies in children with bronchial asthma.
Correlation between total serum IgE levels and RAST scores in a total of 342 asthmatic children were evaluated. The median and range of serum IgE were 1,050 IU/mL and 20 to 10,000 IU/mL respectively. Positive rates of RAST were highest for mites and house dust (87% to 91%) and lowest for milk, dogs, buckwheat, and eggs (2% to 8%). In general, patients with higher RAST scores had higher serum IgE (P less than .05, Mann-Whitney test). In individual cases, however, serum IgE levels did not significantly correlate with RAST scores and RAST was mandatory to estimate the levels of specific IgE antibodies.
D000293:Adolescent; D000485:Allergens / Q000276:immunology; D000918:Antibody Specificity; D001249:Asthma / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004391:Dust; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis* / Q000276:immunology; D008297:Male; D014197:Trees / Q000276:immunology
D000485:Allergens; D004391:Dust; D007073:Immunoglobulin E