Auditory brain stem responses in schizophrenic patients.
Auditory brain stem responses (ABR) were recorded from 20 schizophrenic patients, of whom ten were medicated and ten were unmedicated. A matched control group consisted of ten normal subjects. A statistically significant difference in the latencies of N3 and N5 recordings was found among the three groups. The results suggest that unmedicated schizophrenics have a delayed latency for peaks N3 and N5, and that medication (with neuroleptic drugs) shortens these delayed latencies back to the normal range.
D000328:Adult; D001933:Brain Stem / Q000502:physiology*; D005072:Evoked Potentials, Auditory / Q000187:drug effects; D005260:Female; D006220:Haloperidol / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D012559:Schizophrenia / Q000188:drug therapy / Q000503:physiopathology*
D006220:Haloperidol