Transient vasopressin-resistant diabetes insipidus of pregnancy.
A case of transient vasopressin-resistant diabetes insipidus is reported, which developed during the seventh month of pregnancy and remitted postpartum. The patient was resistant to large doses of deamino-D-arginine vasopressin as well as to aqueous pitressin. She was treated with hydrochlorothiazide. Evidence that prostaglandins may play a role in this syndrome is discussed.
D000328:Adult; D003894:Deamino Arginine Vasopressin / Q000627:therapeutic use*; D003919:Diabetes Insipidus / Q000188:drug therapy / Q000209:etiology*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use*; D009994:Osmolar Concentration; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D013997:Time Factors; D014667:Vasopressins / Q000627:therapeutic use*
D006852:Hydrochlorothiazide; D014667:Vasopressins; D003894:Deamino Arginine Vasopressin