Disseminated superficial actinic porokeratosis. Coexistence with other porokeratotic variants.
The coexistence of disseminated superficial actinic porokeratosis (DSAP) with other variants of porokeratosis is rare. We report three such cases: DSAP with porokeratosis of Mibelli; DSAP with linear porokeratosis; and DSAP occurring in the mother of a girl with linear porokeratosis. Although different areas of skin and different family members usually express the same morphological variant, we suggest that the simultaneous expression of two closely linked gene loci could explain the coexistence of different porokeratotic variants.
D000293:Adolescent; D005260:Female; D006801:Humans; D007642:Keratosis / Q000150:complications* / Q000235:genetics / Q000473:pathology; D008875:Middle Aged