title: Uveal melanoma necrosis after helium ion therapy.
abstract: A 71-year-old man underwent enucleation because of intractable pain ten months after receiving helium ion therapy for a uveal melanoma. There was no clinical or ultrasonographic evidence of tumor regression but histologically the tumor appeared almost entirely necrotic.
mesh_terms: D000368:Aged; D001766:Blindness / Q000209:etiology; D006371:Helium / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D009336:Necrosis / Q000150:complications / Q000601:surgery; D010146:Pain / Q000209:etiology; D011868:Radioisotopes / Q000627:therapeutic use*; D014604:Uveal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery
chemical_list: D011868:Radioisotopes; D006371:Helium