Interpretation of genotoxicity data in assessing the risks of genetic diseases.
Two aspects of genetic risk assessment have been discussed briefly. Some new results concerning the logical development of mutagenic screening programs have been reviewed. In addition, a brief introduction to quantitative risk estimation has been given.
D000014:Abnormalities, Drug-Induced; D004353:Drug Evaluation, Preclinical; D030342:Genetic Diseases, Inborn / Q000453:epidemiology*; D006801:Humans; D009153:Mutagens; D012306:Risk; D013723:Teratogens / Q000633:toxicity*
D009153:Mutagens; D013723:Teratogens