title: [Obesity and hypersomnia].
abstract: Seventy one patients with hypersomniac paroxysms--Pickwickian and Kleine-Levin syndromes, were studied, the incidence of combination of hypersomnia and obesity--followed up. They are supposed to have common pathogenetic mechanisms, giving weight to lesions of hypothalamo-reticulo-limbic structures in viral infections, craniocerebral traumas, intoxications and tumours. The pathological processes advanced in the reticulo-hypothalamo-hypophyseal region lead to hormonal regulatory disorders and disturbances in adaptation and compensatory mechanisms of metabolism, of lipid metabolism including, of sleep and vigilance. A schematic central explanation of the inter-relations of obesity and hypersomnias is presented.
mesh_terms: D000328:Adult; D006970:Disorders of Excessive Somnolence / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D006963:Hyperphagia / Q000175:diagnosis / Q000209:etiology; D008297:Male; D009290:Narcolepsy / Q000175:diagnosis / Q000209:etiology; D009765:Obesity / Q000150:complications*; D010845:Obesity Hypoventilation Syndrome / Q000175:diagnosis / Q000209:etiology; D012893:Sleep Wake Disorders / Q000209:etiology*; D013577:Syndrome
vernacular_title: Zatlŭstiavane i khipersomnii.