[Remissions and acute toxicity during accelerated fractionated irradiation of non-small-cell bronchial carcinoma].
Accelerated fractionation (total dose 66 Gy, single dose 1.8 to 2 Gy, 1 to 2 fractions daily, total treatment period 4 to 5.5 weeks) brings about more than 40% of complete remissions and more than 90% of objective remissions (assessed by radiology) of non-small cell bronchogenic carcinomas. Tumor-induced symptoms are improved in more than 90%. A treatment period of less than four weeks causes considerable acute (and persistent) oesophageal reactions. In case of a treatment period of more than five weeks there is no substantial increase of toxicity.
D000230:Adenocarcinoma / Q000532:radiotherapy; D000368:Aged; D002277:Carcinoma / Q000532:radiotherapy; D002283:Carcinoma, Bronchogenic / Q000532:radiotherapy*; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D013997:Time Factors
Remissionen und akute Toxizität bei beschleunigt fraktionierter Bestrahlung nichtkleinzelliger Bronchialkarzinome.