Tumor genesis syndrome. Hypophosphatemia accompanying Burkitt's lymphoma cell leukemia.
A case of Burkitt's lymphoma cell leukemia with recurrent hypophosphatemia that coincided with tumor growth, and hyperphosphatemia during tumor lysis is presented. Redistribution of body phosphorus with increased uptake by the rapidly replicating tumor cells is suggested. Tumor genesis syndrome seems to us to be a proper term to include metabolic abnormalities that result directly from tumor growth.
D000328:Adult; D002051:Burkitt Lymphoma / Q000097:blood* / Q000150:complications / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D006128:Growth; D006801:Humans; D007668:Kidney / Q000502:physiology; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007938:Leukemia / Q000150:complications / Q000473:pathology; D008297:Male; D009369:Neoplasms / Q000209:etiology / Q000503:physiopathology*; D010710:Phosphates / Q000097:blood* / Q000378:metabolism / Q000652:urine
D010710:Phosphates; D007770:L-Lactate Dehydrogenase