Posttraumatic occurrence of infantile digital fibromatosis. A histologic and electron microscopic study.
We encountered a patient with infantile digital fibromatosis. The representative lesion was a firm, indurated nodule, which developed in the scar of a previous injury on the skin of the left thigh of an 11-year-old girl. Electron microscopy revealed tumor cells that were strongly reminiscent of myofibroblasts. Histopathologically, the cytoplasmic inclusion bodies in the tumor cells stained positively or negatively with hematoxylin-eosin. Electron microscopically, they were either well-defined dense bodies that often showed a doughnutlike appearance or ill-demarcated dense bodies. Spotty calcified foci were seen in the central area of the tumor mass.
D002648:Child; D002921:Cicatrix / Q000150:complications; D005260:Female; D005350:Fibroma / Q000209:etiology* / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D007869:Leg Injuries / Q000150:complications*; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology / Q000648:ultrastructure; D013848:Thigh