title: Calculation of glomerular filtration rate in infants and children. The use of one- and two-compartment models.
abstract: Radiopharmaceuticals such as chromium-51-ethylenediamine tetra-acetic acid and technetium-99m-diethylenetriamine penta-acetic acid are often used to measure glomerular filtration rate. Some assumptions are inherent in the method while others are made to simplify the procedure. The assumption of a one-compartment model falls into the latter group and is an important cause of misleading results.
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005919:Glomerular Filtration Rate; D006801:Humans; D007223:Infant; D007677:Kidney Function Tests / Q000379:methods*; D007678:Kidney Glomerulus / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging