Prophylactic effect of a Beta vulgaris extract on experimental influenza infection in mice.
An aqueous Beta vulgaris extract was repeatedly administered to mice by intranasal (i.n.) instillation, prior to i.n. inoculation of influenza virus A/PR/8/34 (H1N1). The extract conferred a partial protection against the experimental influenza infection: there was a significant decrease in the hemagglutination titers recorded in mouse lung homogenates, a decrease in mortality rate and an increase in the mean survival time as compared with the untreated, virus-inoculated controls.
D000818:Animals; D004353:Drug Evaluation, Preclinical; D006389:Hemagglutinins, Viral / Q000032:analysis; D009980:Influenza A virus / Q000276:immunology; D008168:Lung / Q000276:immunology; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000276:immunology / Q000401:mortality / Q000517:prevention & control*; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D013997:Time Factors
D006389:Hemagglutinins, Viral; D010936:Plant Extracts