title: Discoloration of hydrogel contact lenses under standard care regimens.
abstract: Four types of hydrogel contact lenses (N = 164) were subjected to in vivo and in vitro standard care regimens for a period of six months. Lens care variables included: heat disinfection in Bausch and Lomb Sensitive Eyes saline solution; heat disinfection in Cooper Unisol 4 sterile, nonpreserved saline solution; American Optical/Reichert Lensept disinfection and storage in Sensitive Eyes saline; and Lensept disinfection and storage in Unisol 4 saline. The study was conducted to determine the conditions under which lens discoloration occurs. The 45% Bufilcon A (55% water) lens showed significant discoloration in vivo with both heat and Lensept disinfection when rinsed and soaked in sorbate-preserved saline, and in vitro when heat disinfected in sorbate-preserved saline.
mesh_terms: D003116:Color; D003258:Consumer Behavior; D003263:Contact Lenses, Hydrophilic; D004203:Disinfection / Q000379:methods*; D004868:Equipment Failure; D006358:Hot Temperature / Q000009:adverse effects; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects; D012965:Sodium Chloride; D013011:Sorbic Acid / Q000009:adverse effects; D013242:Sterilization / Q000379:methods*; D014785:Vision, Ocular
chemical_list: D011310:Preservatives, Pharmaceutical; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols; D012965:Sodium Chloride; D013011:Sorbic Acid