title: [Possible role of the thymus in the mechanism of the adjuvant effect of retinoic acid].
abstract: Administration of retinoic acid and of its esters into experimental animals stimulated proliferation of thymus lymphocytes, decreased the tetraploid lymphocytes and increased the amount of diploid cells. The thymus mass tended to decrease as a result of contraction in the area of the gland cortical layer. Alterations in blood, which occurred in presence of retinoic acid, may be responsible for the effect observed.
mesh_terms: D000276:Adjuvants, Immunologic; D000818:Animals; D004247:DNA / Q000032:analysis; D005260:Female; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000276:immunology*; D014212:Tretinoin / Q000031:analogs & derivatives / Q000276:immunology*
chemical_list: D000276:Adjuvants, Immunologic; C041556:methyl 7,8-dihydroretinoate; D014212:Tretinoin; D004247:DNA; C026296:methyl retinoate
vernacular_title: Vozmozhnaia rol' timusa v mekhanizme ad''iuvantnogo deĭstviia retinoevoĭ kisloty.