Small bowel obstruction from an antacid bezoar: a ranitidine-antacid interaction?
A 63-year-old man had an acute small bowel obstruction while being treated with ranitidine and self-prescribed antacid. On exploration, a firm mass, chemically similar to the ingested antacid, was found impacted in the terminal ileum. We believe the effect of ranitidine on gastric secretory volume was the cause of the antacid concretion.
D000536:Aluminum Hydroxide / Q000009:adverse effects*; D001630:Bezoars / Q000150:complications*; D004338:Drug Combinations / Q000009:adverse effects; D004347:Drug Interactions; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D007421:Intestine, Small; D008274:Magnesium / Q000009:adverse effects*; D008276:Magnesium Hydroxide / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011899:Ranitidine / Q000009:adverse effects*
D004338:Drug Combinations; C013591:aluminum hydroxide, magnesium hydroxide, drug combination; D000536:Aluminum Hydroxide; D011899:Ranitidine; D008274:Magnesium; D008276:Magnesium Hydroxide