title: [Efficacy of experimental active specific immunotherapy and immunoprevention of malignant gliomas of the brain].
abstract: The authors conducted experiments to study the efficacy of active specific immunotherapy and immunoprophylaxis with tumor cell lysate obtained by means of metabolites of Bac. mesentericus AB-56 in inoculated malignant glioma of the brain. Active immunotherapy was found to produce the best effect in the early latent period of tumor growth. It was less effective when tumor cells were inoculated in large doses and when the treatment was applied late. The investigated method of tumor cell inactivation was not used previously in neuro-oncology.
mesh_terms: D000818:Animals; D000912:Antibodies, Neoplasm / Q000096:biosynthesis; D001932:Brain Neoplasms / Q000276:immunology / Q000517:prevention & control / Q000628:therapy*; D005260:Female; D005910:Glioma / Q000276:immunology / Q000517:prevention & control / Q000628:therapy*; D007114:Immunization; D008297:Male; D009368:Neoplasm Transplantation; D051381:Rats
chemical_list: D000912:Antibodies, Neoplasm
vernacular_title: Izuchenie éffektivnosti aktivnoĭ spetsificheskoĭ immunoterapii i immunoprofilaktiki zlokachestvennykh gliom golovnogo mozga v éksperimente.