Evidence for the presence of volume-sensitive KCl transport in 'young' human red cells.
'Young' human red cells are shown to possess a specific K+ pathway which is dependent on Cl- and sensitive to cell volume. This system was latent in 'mature' cells but was revealed by high hydrostatic pressure. This suggests the pathway is functionally active in 'young' cells but becomes masked with cell maturation.
D001692:Biological Transport; D002712:Chlorides / Q000494:pharmacology; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000166:cytology* / Q000378:metabolism; D006801:Humans; D006874:Hydrostatic Pressure; D007700:Kinetics; D011188:Potassium / Q000097:blood; D011189:Potassium Chloride / Q000097:blood*; D012156:Reticulocytes / Q000378:metabolism
D002712:Chlorides; D011189:Potassium Chloride; D011188:Potassium