title: Prevention of primary wound infection in neurosurgical patients: a 10-year study.
abstract: Two neurosurgeons in private practice at three community hospitals followed a regimen of antimicrobial prophylaxis for 10 years. No primary wound infection occurred in a series of 2000 consecutive major operations. The study gives rise to certain recommendations for the prevention of postoperative sepsis in neurosurgical patients.
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002557:Cerebrospinal Fluid Shunts / Q000009:adverse effects; D003399:Craniotomy / Q000009:adverse effects; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000188:drug therapy / Q000209:etiology; D007796:Laminectomy / Q000009:adverse effects; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D009493:Neurosurgery; D011322:Primary Prevention / Q000379:methods; D011512:Proteus Infections / Q000188:drug therapy / Q000209:etiology; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000209:etiology; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents