[Effect of corinfar on the dynamic function and various indices of glycolysis and glycogenolysis in the thrombocytes of patients with unstable stenocardia].
An increase in the aggregation properties of platelets accompanied by the activation of glycogenolysis and glycolysis was established in patients with unstable angina as compared to a control group of healthy persons. In most cases corinfar therapy resulted in a positive time course of the main platelet indices and a marked improvement of the patients' status. The correlation between the platelet aggregation index and phosphorylase A activity and their association with a course of disease indicated an opportunity of using these indices as accessory diagnostic criteria and control over therapeutic efficacy in unstable angina.
D000328:Adult; D000787:Angina Pectoris / Q000097:blood*; D000789:Angina, Unstable / Q000097:blood* / Q000188:drug therapy; D001792:Blood Platelets / Q000187:drug effects*; D005260:Female; D006003:Glycogen / Q000097:blood*; D006019:Glycolysis / Q000187:drug effects*; D006593:Hexokinase / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D010762:Phosphorylase a / Q000097:blood; D010973:Platelet Adhesiveness / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects
D006003:Glycogen; D010762:Phosphorylase a; D006593:Hexokinase; D009543:Nifedipine
Vliianie korinfara na dinamicheskie funktsii i nekotorye pokazateli glikoliza i glikogenoliza trombotsitov u bol'nykh nestabil'noĭ stenokardieĭ.