Ewing's sarcoma of the scapula with metastases to the lung and eye.
A small, round cell tumor of the left scapula was found in a 3-month-old female Caucasian child. The histology was consistent with Ewing's sarcoma. Subsequently, a solitary pulmonary metastasis was excised. Thirty-one months after diagnosis, the child presented with leukokoria and a solitary pleural metastasis. The histology of both was identical to that of the original scapular tumor. G-banded karyotypes of the pulmonary metastasis and the ocular tumor revealed the presence of a balanced translocation, 46,XX, t(11;22)(q24;q12), which supported the original diagnosis of Ewing's sarcoma.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D002871:Chromosome Banding; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005134:Eye Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008175:Lung Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D012512:Sarcoma, Ewing / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D012540:Scapula; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D003520:Cyclophosphamide