[New experimental findings on immunity and autoimmunity in old age].
The peripheral blood lymphocytes of subjects of old age can be characterized as follows: deteriorated immunoglobulin synthesis under PWM stimulation, improved immunoglobulin synthesis under autoantigen (DNA) addition, increase in the anti-DNA auto-antibody synthesis, 4. higher sensitivity of the PHA-induced lymphocyte proliferation to prednisolone. The in-vitro methods have a model character for further investigations on the regulation of the immunological system and its possible therapeutical influencing.
D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D006801:Humans; D007109:Immunity; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000276:immunology*; D011239:Prednisolone / Q000494:pharmacology
D001323:Autoantibodies; D011239:Prednisolone
Neue experimentelle Erkenntnisse zu Immunität und Autoimmunität im Alter.