The significance of the fibrin/fibrinogen degradation product in serum of carcinoma patients with hematogenous metastasis.
Fibrin/fibrinogen degradation product (FDP) was measured in 270 cases with various carcinomas. An elevation of FDP (5 micrograms/ml or more) was observed in 68 cases (25%). Of the 68 elevated FDP cases, 5 (82%) were inoperable or received nonradical resection. Forty of those 56 cases (71%) showed hematogenous metastasis. FDP in those cases which showed hematogenous metastasis was found to be due to fibrinolysis accompanied by consumption coagulopathy.
D001777:Blood Coagulation; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D009362:Neoplasm Metastasis / Q000503:physiopathology*; D009369:Neoplasms / Q000097:blood* / Q000150:complications / Q000473:pathology
D005338:Fibrin Fibrinogen Degradation Products