Softisan--a new vehicle for patch testing.
Petrolatum is a good vehicle for many patch test allergens, because it is stable, unreactive, and allergy to it is rare. Some difficulties exist, however, when water-soluble allergens are tested, because emulsifiers are often needed; these can change the properties of both the test material and the vehicle itself. In the present study, we compared petrolatum with a new lanolin substitute based on vegetable fatty acids as a patch test vehicle for nickel sulphate.
D000293:Adolescent; D000328:Adult; D000368:Aged; D003877:Dermatitis, Contact / Q000175:diagnosis*; D005260:Female; D005989:Glycerides; D006801:Humans; D007809:Lanolin; D008297:Male; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D010328:Patch Tests / Q000379:methods*; D010577:Petrolatum; D014677:Pharmaceutical Vehicles; D012882:Skin Tests / Q000379:methods*
D005989:Glycerides; D014677:Pharmaceutical Vehicles; C029938:nickel sulfate; D009532:Nickel; D007809:Lanolin; D010577:Petrolatum; C049519:softisan 649