title: Progress-curve analysis in enzyme kinetics. Numerical solution of integrated rate equations.
abstract: Progress curves of enzyme-catalysed reactions are described by equations of a type that precludes direct calculation of the extent of reaction at any time. Previously, such equations have been solved by the Newton-Raphson method, but this procedure may fail when based upon the usual formulae. An alternative formulation is proposed that is both quicker and more robust.
mesh_terms: D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D008722:Methods; D008956:Models, Chemical
chemical_list: D004798:Enzymes