Trichodermodysplasia with dental alterations: an apparently new genetic ectodermal dysplasia of the tricho-odonto-onychial subgroup.
A mother and two children with trichodysplasia, hypodontia, onychodysplasia (not present in the mother), mild skin alterations, bilateral inward deflection of the 4th toes, and other findings are described. This is an ectodermal dysplasia of the tricho-odonto-onychial subgroup probably due to an autosomal dominant gene.
D000328:Adult; D000848:Anodontia / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D003878:Dermatoglyphics; D004476:Ectodermal Dysplasia / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D006197:Hair / Q000002:abnormalities*; D006801:Humans; D008297:Male; D009264:Nails, Malformed / Q000235:genetics; D010375:Pedigree