Nasal allergy and nasal polyp with special reference to the mucosal IgE antibodies.
Immunologic conditions were studied in 8 patients with nasal allergies and nasal polyps and in 20 patients with nasal polyps. The present study showed the following: Nasal polyp mucosa contains a low level of mucosal IgE antibodies; nasal polyp mucosa is devoid of or deficient in the capacity of producing IgE antibodies; the presence of mucosal IgE antibodies in nasal polyp mucosa does not always imply the clinical manifestation of nasal allergies, and the antigen and antibody interaction does not always result in nasal symptoms.
D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D008407:Mast Cells / Q000648:ultrastructure; D008854:Microscopy, Electron; D009297:Nasal Mucosa / Q000276:immunology* / Q000473:pathology; D009298:Nasal Polyps / Q000276:immunology* / Q000473:pathology; D011852:Radioallergosorbent Test; D012221:Rhinitis, Allergic, Perennial / Q000276:immunology* / Q000473:pathology
D007073:Immunoglobulin E