Biocompatibility aspects of cellophane, cellulose acetate, polyacrylonitrile, polysulfone and polycarbonate hemodialyzers.
The biocompatibility of cuprammonium rayon (Cu), cellulose acetate, polysulfone (Ps) and polyacrylonitrile hollow-fiber dialyzers and a polycarbonate-polyether flat plate dialyzer has been investigated. The Cu dialyzer resulted in more complement activation and a greater degree of leukopenia than the others, while the Ps hollow-fiber dialyzer appeared to be the most biocompatible of the membrane equipment in this study. These results were confirmed by in vitro evaluations and microscopic examinations of the different dialyzers.
D000180:Acrylic Resins; D001672:Biocompatible Materials; D002476:Cellophane; D002482:Cellulose / Q000031:analogs & derivatives; D005069:Evaluation Studies as Topic; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D007958:Leukocyte Count; D008567:Membranes, Artificial; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009000:Monocytes / Q000166:cytology; D009504:Neutrophils / Q000166:cytology; D011076:Polycarboxylate Cement; D011108:Polymers; D006435:Renal Dialysis; D013450:Sulfones
D000180:Acrylic Resins; D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011076:Polycarboxylate Cement; D011108:Polymers; D013450:Sulfones; C010504:polyacrylonitrile; C017662:polysulfone P 1700; C005506:polycarbonate; C005062:acetylcellulose; D002482:Cellulose; D002476:Cellophane