Intrascrotal tumors in the older male.
Although the greatest incidence of testicular neoplasms is in the age group 20 to 35.9% of all intrascrotal tumors occur in males over 60. They may be classified into four major groups based on the tissue origin of the tumor. The most common group comprising 50% are lymphoreticular neoplasms or lymphomas. They occur in both blacks and whites, result in a diffuse enlargement of the testis and commonly involve the epididymis and cord. Prognosis is poor and survival is usually less than two years. Germ cell tumors comprise 25% and the tumors are usually large. Most of them are the classical seminoma which has a good prognosis following orchiectomy and retroperitoneal radiation. A few are the spermatocytic seminoma which is usually benign. Three percent are teratocarcinoma with embryonal elements which is highly malignant and survival less than two years. Ten percent are tumors of gonadal stromal origin. There are two types, the Leydig cell and the more rare Sertoli cell. About one-fourth of these patients develop gynecomastia and some a decrease in libido. The prognosis is good as less than 10% of these tumors are malignant. Neoplasms of supportive and paratesticular structures comprise a heterogeneous group of benign and malignant lesions and comprise about 15% of intrascrotal tumors. Most of them have the same features as tumors of similar tissues encountered throughout the body. They are the mesothelioma or adenomatoid tumor, fibroma, rhabdomyosarcoma, leiomyoma, lipoma, liposarcoma, mucinous cystadenocarcinoma, and leiomyosarcoma. As in all intrascrotal tumors, the diagnosis, treatment, and prognosis are based on the microscopic findings after removal of the tumor.
D000367:Age Factors; D000368:Aged; D004407:Dysgerminoma / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D007984:Leydig Cell Tumor / Q000453:epidemiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012208:Rhabdomyosarcoma / Q000453:epidemiology / Q000473:pathology; D012707:Sertoli Cell Tumor / Q000453:epidemiology / Q000473:pathology; D013724:Teratoma / Q000453:epidemiology / Q000473:pathology; D013736:Testicular Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy