C3 nephritic factor in an individual with recurrent viral infection and lipodystrophy.
A patient with nephritic factor in the serum following an attack of disseminated herpes is described. In the majority of cases, the factor is associated with mesangio-capillary glomerulonephritis, with or without partial lipodystrophy. It has, however, been described in cases of partial lipodystrophy alone, in one patient with recurrent pyogenic infections, and in one healthy individual. It has not previously been described in an individual with disseminated viral infection.
D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D003176:Complement C3 / Q000032:analysis; D003178:Complement C3 Nephritic Factor / Q000097:blood*; D003169:Complement Inactivator Proteins / Q000097:blood*; D006561:Herpes Simplex / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D008060:Lipodystrophy / Q000097:blood*; D008297:Male
D000936:Antigen-Antibody Complex; D003176:Complement C3; D003178:Complement C3 Nephritic Factor; D003169:Complement Inactivator Proteins