Multinucleate Leydig cells in normal human testes.
The number of mononucleate and multinucleate Leydig cells per unit area of the testis was determined in normal adult men using the peroxidase-anti-peroxidase method for testosterone detection. The results of this study indicate that the number of multinucleate Leydig cells increases markedly with age, whereas the total Leydig cell population decreases.
D000328:Adult; D000368:Aged; D000375:Aging; D002452:Cell Count; D002467:Cell Nucleus / Q000648:ultrastructure*; D006651:Histocytochemistry; D006735:Horseradish Peroxidase / Q000378:metabolism; D006801:Humans; D007985:Leydig Cells / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D013739:Testosterone / Q000032:analysis
D013739:Testosterone; D006735:Horseradish Peroxidase