title: Charcoal and isoniazid pharmacokinetics.
abstract: Activated charcoal (10 g) administered 1 h after a 600 mg oral dose of isoniazid to six healthy subjects did not reduce the area under the plasma concentration-time curve for isoniazid significantly. Charcoal administration is unlikely to be of value in isoniazid poisoning if delayed by an hour or more after the overdose.
mesh_terms: D000107:Acetylation; D002606:Charcoal / Q000494:pharmacology*; D005260:Female; D006207:Half-Life; D006801:Humans; D007538:Isoniazid / Q000378:metabolism* / Q000506:poisoning; D007700:Kinetics; D008297:Male
chemical_list: D002606:Charcoal; D007538:Isoniazid