title: Thrombotic occlusion of a Bjork-Shiley mitral valve.
abstract: Thrombosis of a mechanical cardiac valve is a complication potentially preventable by adequate anticoagulation. A patient is described who discontinued anticoagulant therapy, with resultant near-fatal thrombosis of a mitral Bjork-Shiley valve. The literature is reviewed concerning the incidence of thrombotic prosthetic valve occlusion in the various anatomical sites and potential factors contributing to its occurrence.
mesh_terms: D000328:Adult; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008943:Mitral Valve; D010349:Patient Compliance; D011183:Postoperative Complications / Q000209:etiology* / Q000517:prevention & control; D013927:Thrombosis / Q000209:etiology* / Q000517:prevention & control; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D014859:Warfarin