title: [Effect of ubiquinone-9 on the blood coagulation system].
abstract: The effect of a single and 2-week administration of ubiquinone-9 on the blood coagulation system and the functional activity of platelets was studied in the experiments in vitro and in vivo on rats. It was shown that a single dose of 150 mg/kg of ubiquinone decreased adhesion and that of 5 mg/kg decreased aggregation of platelets. Both with a single and 2-week drug administration in doses of 5, 50 and 150 mg/kg an insignificant decrease of coagulability was observed.
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005342:Fibrinolysis / Q000187:drug effects; D008297:Male; D010973:Platelet Adhesiveness / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count / Q000187:drug effects; D051381:Rats; D013997:Time Factors; D014451:Ubiquinone / Q000494:pharmacology*
chemical_list: D014451:Ubiquinone; C030571:ubiquinone 9
vernacular_title: Vliianie ubikhinona-9 na svertyvaiushchuiu sistemu krovi.