[Changes in the SH-group level and respiration during gamma- and Fe2+-induced lipid peroxidation in Ehrlich ascites carcinoma cells].
In experiments on Ehrlich ascites tumor cells it was shown that lipid peroxidation induced by gamma-rays and Fe2+ ions was accompanied by a decrease in the endogenous SH-group content at early times after exposure (during 3-hour incubation). It was also established that no significant changes occurred in the oxygen uptake by Ehrlich ascites tumor cells depending on radiation dose of Fe2+ ion concentration. If cells were pre-kept under hypotonic conditions an additional decrease in cell respiration and SH-group content and activation of lipid peroxidation was noted.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002478:Cells, Cultured; D005296:Ferrous Compounds / Q000494:pharmacology*; D005720:Gamma Rays; D007501:Iron / Q000494:pharmacology*; D008054:Lipid Peroxides / Q000378:metabolism / Q000528:radiation effects*; D051379:Mice; D010101:Oxygen Consumption / Q000187:drug effects / Q000528:radiation effects*; D013438:Sulfhydryl Compounds / Q000378:metabolism / Q000528:radiation effects*
D005296:Ferrous Compounds; D008054:Lipid Peroxides; D013438:Sulfhydryl Compounds; D007501:Iron
Izmenenie soderzhaniia SH-grupp i dykhaniia v protsesse gamma- i Fe2+-indutsirovannogo perekisnogo okisleniia lipidov v kletkakh astsitnoĭ kartsinomy Erlikha.