title: Artificially depleted plasma for manufacturers international calibration of thromboplastin.
abstract: After initial calibration of a working reference preparation of rabbit brain thromboplastin using fresh plasma samples from patients on anticoagulant therapy according to WHO requirements, manufacturers' subsequent production batches can be internationally calibrated with equal success using dilutions of normal plasma in absorbed normal plasma.
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D006801:Humans; D010949:Plasma; D011817:Rabbits; D013925:Thromboplastin / Q000592:standards*; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D014859:Warfarin; D013925:Thromboplastin