title: [Cardiospecific enzyme activity and clinical significance of the parameters of blood enzymograms in the acute phase of myocardial infarction].
abstract: Serial investigations of the activity of cardiospecific enzymes in the blood allowed one to reveal a prolonged type of a dynamic curve "enzymatic activity-time" characterized by two or more peaks in 66.7% of patients with the acute phase of myocardial infarction. It was assumed that such a curve type could be determined by the formation of multiple necrotic foci in the myocardium. A close correlation between the rate of increment and peak activity of the LDH, CPK and MB-CPK was shown. These and other parameters of the blood enzymogram in the acute phase of myocardial infarction made it possible to assess the development of a necrotic process in the myocardium and, consequently, a clinical course of disease.
mesh_terms: D000368:Aged; D001219:Aspartate Aminotransferases / Q000097:blood*; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000201:enzymology*
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase
vernacular_title: Dinamika aktivnosti kardiospetsificheskikh fermentov i klinicheskoe znachenie parametrov fermentogrammy krovi v ostroĭ faze infarkta miokarda.