[Evaluation of micro- and macrophage function in splenectomized patients--possible dermatologic consequences].
Various micro- and macrophage functions were studied in vitro in 15 patients having previously undergone posttraumatic splenectomy as well as in 100 healthy persons. We found reduced capacity of intracellular inactivation of microorganisms by microphages (7/15) and slight impairment of chemotactic activity in both systems (8/15; 9/13). Possible dermatological consequences are discussed.
D000328:Adult; D002634:Chemotaxis, Leukocyte; D003872:Dermatitis / Q000276:immunology*; D005260:Female; D006801:Humans; D008264:Macrophages / Q000276:immunology*; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis; D011008:Pneumococcal Infections / Q000276:immunology; D018805:Sepsis / Q000276:immunology*; D013156:Splenectomy; D013530:Surgical Wound Infection / Q000276:immunology*
Mikro- und Makrophagenfunktionsprüfungen bei splenektomierten Patienten--mögliche dermatologische Konsequenzen.