title: Alloxan-induced changes in the collagen characteristics in the skin of male garden lizards, Calotes versicolor, from three age groups.
abstract: Alloxan diabetes in lizards Calotes versicolor, belonging to three age groups, induced decreased levels of percentage of solubility of collagen in dorsal and ventral skin regions after 7 days of treatment. Old lizards showed greater susceptibility to alloxan diabetes than lizards of the young and middle-age groups. There appears to be no correlation between blood-glucose level and accelerated ageing of collagen. It is suggested that, in alloxan diabetes, metabolites formed in the tissues might accelerate the ageing of collagen.
mesh_terms: D000375:Aging; D000496:Alloxan; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001835:Body Weight; D003094:Collagen / Q000032:analysis*; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology*; D008112:Liver Glycogen / Q000032:analysis; D008116:Lizards / Q000502:physiology*; D008297:Male; D012867:Skin / Q000032:analysis*; D012995:Solubility
chemical_list: D001786:Blood Glucose; D008112:Liver Glycogen; D000496:Alloxan; D003094:Collagen