Ocular findings in patients with dysplastic nevus syndrome.
Ninety-two patients with biopsy-proven dysplastic nevus syndrome were evaluated ophthalmologically and compared to a non-dysplastic nevus syndrome control population. A statistically significant increase in the percentage of dysplastic nevus syndrome patients versus controls harboring conjunctival nevi (9.78% vs. 1.85%), iris nevi (31.52% vs. 12.96%), and choroidal nevi (18.48% vs. 4.63%) was found. Although not statistically significant, the number of iris nevi encountered per patient was greater for the dysplastic nevus syndrome group. All dysplastic nevus syndrome patients and their families should be evaluated ophthalmologically, with special attention being given to dilated indirect ophthalmoscopy.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002830:Choroid Neoplasms / Q000150:complications; D003230:Conjunctival Neoplasms / Q000150:complications; D005134:Eye Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications*; D013577:Syndrome