[Effect of electrostimulation of the hypothalamus on protein biosynthesis in organs of adult and aged rats].
The effect of hypothalamus electrical stimulation on total protein biosynthesis was studied in skeletal muscle, heart, liver, adrenal cortex and thyroid gland of adult rats. In adult animals hypothalamus stimulation provokes a pronounced increase in 3H-leucine incorporation into total protein of all tissues, as well as into liver chromatin proteins. No significant changes were observed in protein biosynthesis when hypothalamus of old rats was stimulated. This can serve as evidence of age-related decrease in the ability of the hypothalamus to stimulate protein synthesis in peripheral tissues.
D000311:Adrenal Glands / Q000378:metabolism; D000375:Aging; D000818:Animals; D004558:Electric Stimulation; D007031:Hypothalamus / Q000502:physiology*; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D014176:Protein Biosynthesis; D051381:Rats; D011919:Rats, Inbred Strains; D013961:Thyroid Gland / Q000378:metabolism
Vliianie élektrostimuliatsii gipotalamusa na biosintez belka v raznykh organakh vzroslykh i starykh krys.