Probable elimination of swine dysentery after feeding ronidazole, carbadox or lincomycin and verification by feeding sodium arsanilate.
Swine dysentery did not recur during a nine week period after withdrawal of medication in swine fed ronidazole at a level of 60 parts per million of feed for ten weeks or fed either carbadox at 55 ppm or lincomycin at 110 ppm of feed for six weeks. During this period swine dysentery was neither transmitted to accompanying sentinels after the withdrawal of the above medication or was Treponema hyodysenteriae isolated and cultured or observed in stained smears from rectal swabs and feces or from colonic scrapings at necropsy. Beginning three weeks after the withdrawal of medication, all swine were fed sodium arsanilate at a concentration of 220 ppm of feed for three weeks in an attempt to excite the carrier of swine dysentery into developing a swine dysentery diarrhea. A swine dysentery diarrhea did recur during the feeding of sodium arsanilate in swine previously fed ronidazole at a level of 60 ppm of feed for only six weeks. It was concluded: that swine dysentery was probably eliminated with the feeding of ronidazole for the longer duration and with the feeding of carbadox and lincomycin and that sodium arsanilate was of value in identifying the carrier state.
D000818:Animals; D001147:Arsanilic Acid; D001152:Arsenicals; D002218:Carbadox / Q000627:therapeutic use*; D002353:Carrier State / Q000175:diagnosis / Q000662:veterinary*; D004403:Dysentery / Q000517:prevention & control / Q000662:veterinary*; D008034:Lincomycin / Q000627:therapeutic use*; D009593:Nitroimidazoles / Q000627:therapeutic use*; D011810:Quinoxalines / Q000627:therapeutic use*; D012385:Ronidazole / Q000627:therapeutic use*; D013552:Swine / Q000382:microbiology; D013553:Swine Diseases / Q000175:diagnosis / Q000517:prevention & control*; D014211:Treponemal Infections / Q000517:prevention & control / Q000662:veterinary*
D001152:Arsenicals; D009593:Nitroimidazoles; D011810:Quinoxalines; D008034:Lincomycin; D012385:Ronidazole; D002218:Carbadox; D001147:Arsanilic Acid