Visual evoked cortical potential to paracentral retinal stimulation in chronic glaucoma, ocular hypertension, and an age-matched group of normals.
Visual evoked cortical potentials (VECPs) to midperipheral stimulation of the visual field were elicited in age-matched groups of patients with unilateral chronic simple glaucoma or ocular hypertension and normal subjects. With a multimodal stimulus approach comprising transient and steady-state pattern reversal and transient onset-offset VECPs, 82.1% of the glaucoma group and 50.9% of the ocular hypertensives revealed significant abnormalities (p less than 0.01) in one or more of the electrophysiological features measured, i.e., latency, phase, amplitude, and contrast threshold.
D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology*; D002908:Chronic Disease; D005074:Evoked Potentials, Visual; D005901:Glaucoma / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology*; D010775:Photic Stimulation; D012016:Reference Values; D012160:Retina / Q000503:physiopathology*; D012684:Sensory Thresholds