Analgesia following arthroscopic surgery: comparison of diflunisal and acetaminophen with codeine.
In this study, 40 postarthroscopy patients were treated with either diflunisal or acetaminophen with codeine to control postoperative pain. In comparing these two drugs, better known as Dolobid and Tylenol #3, the results were comparable, though acetaminophen with codeine seemed to have a more rapid onset of action. Diflunisal provided better continuity of analgesia and less frequent dosing.
D000082:Acetaminophen / Q000009:adverse effects / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D000698:Analgesia; D003061:Codeine / Q000009:adverse effects / Q000627:therapeutic use*; D004061:Diflunisal / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D008297:Male; D010149:Postoperative Pain / Q000188:drug therapy*; D012459:Salicylates / Q000627:therapeutic use*
D004338:Drug Combinations; D012459:Salicylates; D000082:Acetaminophen; D004061:Diflunisal; D003061:Codeine