Lymphadenopathy in dogs associated with aluminosilicate.
Granulomatous lymphadenopathy, associated with the presence of needle-like refractile particles, was recognised in two dogs. The material was detected in macrophages, either free within the cytoplasm or in membrane-bound lysosomes. By mineral analysis under direct vision in an electron microscope microanalyser (EMMA 4) the particles were found to contain aluminosilicate.
D000538:Aluminum Silicates / Q000032:analysis / Q000633:toxicity*; D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced / Q000473:pathology*; D004285:Dogs; D005260:Female; D008198:Lymph Nodes / Q000473:pathology / Q000648:ultrastructure; D008206:Lymphatic Diseases / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D008247:Lysosomes / Q000648:ultrastructure; D008854:Microscopy, Electron
D000538:Aluminum Silicates; C049037:aluminosilicate