title: A comparison of the effects of immobilization and continuous passive motion on surgical wound healing in mature rabbits.
abstract: The purpose of this investigation was to compare the effects of continuous passive motion (CPM) and cast immobilization on postoperative wound healing. Medical parapatellar skin incisions and arthrotomies were performed on both knees of 10 mature New Zealand rabbits. After closure of the incisions, one knee was immobilized in a cast while the other was treated by continuous passive motion for 3 weeks. Six standardized skin specimens (2 mm wide) from each wound were tested to failure and one specimen was examined histologically. With respect to the breaking force, tensile strength, strain at failure, stiffness, and toughness, the wounds in the continuous-passive-motion group were significantly stronger, stiffer, and tougher than those in the cast group. Histologically, the structural organization of the collagen fibers was also superior in the scars treated with continuous passive motion. The results of the present investigation indicate that compared to immobilization, continuous passive motion enhances postoperative wound healing in rabbits.
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D062109:Dermatologic Surgical Procedures; D007103:Immobilization; D007719:Knee Joint / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D009068:Movement; D011182:Postoperative Care; D011817:Rabbits; D012867:Skin / Q000473:pathology / Q000503:physiopathology; D013718:Tensile Strength; D014945:Wound Healing