title: Performance and biocompatibility of the FD 100 Gambrane hollow-fiber dialyzer.
abstract: In order to obtain performance data and biocompatibility characteristics of the two new Gambrane FD 100 polycarbonate hollow-fiber dialyzers (y-sterilized, dry or prefilled with isotonic saline) a paired in vivo evaluation was carried out. The measured data indicate that residual blood volume and small molecular weight clearances of Gambrane hollow-fiber dialyzers are not significantly different from comparable Cuprophan dialyzers. Small molecular clearance values are not affected by the significantly different ultrafiltration coefficients of the two tested FD 100 dialyzers. Biocompatibility of Gambrane as reflected by white blood cell count, platelet count and C3d is superior to Cuprophan.
mesh_terms: D001672:Biocompatible Materials; D003404:Creatinine / Q000097:blood; D005069:Evaluation Studies as Topic; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D010710:Phosphates / Q000097:blood; D011076:Polycarboxylate Cement; D006435:Renal Dialysis / Q000379:methods*; D014462:Ultrafiltration; D014508:Urea / Q000097:blood; D014527:Uric Acid / Q000097:blood
chemical_list: D001672:Biocompatible Materials; D010710:Phosphates; D011076:Polycarboxylate Cement; C005506:polycarbonate; D014527:Uric Acid; D014508:Urea; D003404:Creatinine