title: [Long-term biopsy study of chronic hepatitis].
abstract: Repeated liver biopsy was performed at 293 patients suffering from chronic hepatitis (33 cases of chronic persistent type, 260 cases with mild or mediate activity, 3 highly active cases) in the interval varying from 2 months to 11 years. Unsubstantial portobiliary fibrosis was found in addition to inflammatory changes in 49 cases with mild activity, quiet fibrosis in 4 cases, unstabilized cirrhosis in 3 cases; unchanged morphology occurred but once after 4 year monitoring. Two patients with chronic persistent hepatitis showed the same picture in repeated biopsy. Both types of chronic hepatitis were obviously different as a rule but prospective difficulties in distinguishing between them are not lacking.
mesh_terms: D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006505:Hepatitis / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008297:Male; D008875:Middle Aged
vernacular_title: Dlouhodobé bioptické sledóvání chronické hepatitidy.