title: Monoclonal antibodies against Chilo iridescent virus (iridovirus type 6). Brief report.
abstract: Mouse hybridomas producing antibodies against proteins of Chilo Iridescent Virus were established by fusions of X 63-Ag 8-653 myeloma cells with spleen cells from balb/c mice immunized with purified disrupted viral particles. Forty monoclonal antibodies to CIV proteins have been characterized. By ELISA, 4 categories of monoclonal antibodies were defined according to their ability to react with some selected viral protein fractions used as antigen. In preliminary studies, the specificity of 2 monoclonal antibodies for some viral polypeptides was determined by immunoblotting.
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000914:Antibodies, Viral / Q000276:immunology*; D000918:Antibody Specificity; D007497:Iridoviridae / Q000276:immunology*; D051379:Mice; D008970:Molecular Weight; D014764:Viral Proteins / Q000032:analysis / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D014764:Viral Proteins