The clinical application of molecular biology in colorectal cancer.
In the last three years, the melding of knowledge of retroviruses, oncogenes, and growth factors has revolutionized the understanding of cellular growth control in both normal and neoplastic cells. Monoclonal antibodies against oncogene products expressed in malignancy provide the clinician with new diagnostic and therapeutic modalities, which can have major applications in the field of colorectal cancer.
D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D002471:Cell Transformation, Neoplastic; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D009857:Oncogenes; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000628:therapy*
D000911:Antibodies, Monoclonal