title: [Regulation of glucose-6-phosphate dehydrogenase activity of the rat liver in vitamin B1 deficiency].
abstract: Kinetic patterns and thermostability of glucose-6-phosphate dehydrogenase, isolated from liver tissue of intact and thiamine-deficient rats, were analyzed. Distinct alterations were not found in the patterns studied. The data obtained suggest that a decrease in the enzymatic activity, observed after administration of oxythiamine into rats, occurred due to lowering in content of the protein active form.
mesh_terms: D000818:Animals; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism*; D006358:Hot Temperature; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008297:Male; D009249:NADP / Q000378:metabolism; D010427:Pentose Phosphate Pathway; D051381:Rats; D013832:Thiamine Deficiency / Q000201:enzymology*
chemical_list: D009249:NADP; D005954:Glucosephosphate Dehydrogenase
vernacular_title: O reguliatsii aktivnosti gliukozo-6-fosfatdegidrogenazy pecheni krys pri B1-nedostatochnosti.