New macrolides from Penicillium urticae mutant S11R59.
Two new macrolides, patulolide B and patulolide C, were isolated from a culture filtrate of Penicillium urticae S11R59 mutant. The structures of these macrolides were determined and their biological activities were investigated. These structures and biological activities were also compared with those of patulolide A which was produced by the same organism.
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D055598:Chemical Phenomena; D002621:Chemistry; D007783:Lactones / Q000494:pharmacology; D018942:Macrolides; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D010407:Penicillium / Q000032:analysis*; D013055:Spectrophotometry, Infrared
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D007783:Lactones; D018942:Macrolides; C049727:patulolide C; C049726:patulolide B; C049725:patulolide A