title: [Evaluation of the embryotoxic risk of industrial chemicals in pregnancy].
abstract: For the first time exposure levels during pregnancy have been evaluated for industrial chemicals in the German list of "Maximal occupational exposure limits and biological tolerance levels of occupational chemicals 1985" (MAK-Werte-Liste). According to this evaluation only a single substance (methylmercury) is embryotoxic in man, a prenatal risk cannot be excluded for eight chemicals, and 18 chemicals are safe at occupational exposure limits (MAK-Werte). Furthermore, pregnant women should avoid exposure to any of the 112 carcinogenic chemicals of the list and to 26 substances which are under evaluation for embryotoxic properties. Occupational chemicals are subdivided into four pregnancy riskgroups and discussed with respect to prenatal counselling.
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D002273:Carcinogens; D004781:Environmental Exposure; D005260:Female; D005860:Germany, West; D006801:Humans; D007231:Infant, Newborn; D008452:Maximum Allowable Concentration; D009784:Occupational Diseases / Q000139:chemically induced*; D011247:Pregnancy
chemical_list: D000395:Air Pollutants, Occupational; D002273:Carcinogens
vernacular_title: Bewertung des embryotoxischen Risikos von Industriechemikalien in der Schwangerschaft.