Medial hypothalamic stimulation produces analgesia to facial heating in unrestrained rats.
Gradual heating of the face in unrestrained conscious rats produced a behavioural response at a mean threshold temperature of 41.9 degrees C (S.E.M. +/- 0.02, 174 tests). This temperature did not change with tests repeated at 5-min intervals over one hour. During stimulation of the preoptic area of the hypothalamus the response temperature was consistently raised by about 3 degrees C but returned to the control level within 5 min.
D000698:Analgesia; D000818:Animals; D004558:Electric Stimulation; D005145:Face / Q000502:physiology*; D006358:Hot Temperature; D007033:Hypothalamus, Middle / Q000502:physiology*; D008297:Male; D009619:Nociceptors / Q000502:physiology; D010812:Physical Stimulation; D051381:Rats; D011919:Rats, Inbred Strains; D012684:Sensory Thresholds; D014738:Vibrissae