title: Benign cephalic histiocytosis.
abstract: Benign cephalic histiocytosis is a self-healing non-X, nonlipid cutaneous histiocytosis of children, characterized by a papular eruption on the head. Mucous membranes and viscera are always spared. In the 13 cases reported herein, the children were otherwise in good general health. The disease appeared during the first three years of life, and spontaneous regression was complete by the age of nine years in the four cases healed to date. The histiocytic infiltrate was localized in the upper and middle dermis and contained no lipids at any stage of evolution. All the histiocytes contained coated vesicles, and 5% to 30% also contained comma-shaped bodies in their cytoplasm.
mesh_terms: D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D007223:Infant; D008206:Lymphatic Diseases / Q000473:pathology*; D008297:Male; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*