title: Organic brain syndrome associated with marginal hypothyroidism.
abstract: The authors report organic brain dysfunction in two psychiatric patients with grade 2 hypothyroidism; one was depressed and one had a paranoid psychosis with depressive features. The depression and psychosis responded to psychotropic medication and L-thyroxine, but the cognitive dysfunction improved only partially.
mesh_terms: D000368:Aged; D003866:Depressive Disorder / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications*; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000209:etiology*; D010259:Paranoid Disorders / Q000188:drug therapy / Q000209:etiology; D011619:Psychotropic Drugs / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use
chemical_list: D011619:Psychotropic Drugs; D013974:Thyroxine