[Synthesis of gestodene].
The synthesis of the new progestogen, 17 alpha-ethinyl-17 beta-hydroxy-18-methyl-4,15-estradien-3-one (gestodene, 6), starting from 18-methyl-4-estren-3,17-dione (1) can be accomplished by several methods. The oral progestational activity of gestodene is greater than that of levonorgestrel. Gestodene, in combination with ethinylestradiol, is contained in a recently developed oral contraceptive.
D055598:Chemical Phenomena; D002621:Chemistry; D003276:Contraceptives, Oral / Q000138:chemical synthesis*; D009652:Norpregnenes / Q000138:chemical synthesis*
D003276:Contraceptives, Oral; D009652:Norpregnenes; C033273:Gestodene
Synthesen von Gestoden.