title: Multifocal carcinoma of the colon.
abstract: Incidence of multicentric colorectal carcinoma is increasing without any apparent explanation. There are several possible factors in the epidemiology of colon carcinoma and multicentric carcinomas. The so-called polyp-carcinoma sequence has become a matter of increased concern, and ultimately polyp presence should be considered a risk for multiplicity. To reduce the possibility of subsequent new carcinomas, there is a tendency in the management of colon cancer to employ a more radical surgical approach as a prophylactic measure, particularly in patients with multiple primary malignancies or in case of cancer-polyp coexistence.
mesh_terms: D002277:Carcinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012306:Risk