Effects of singular and combined dietary deficiencies of selenium and vitamin E on fingerling channel catfish (Ictalurus punctatus).
Selenium and vitamin E interrelationships in the nutrition of channel catfish (Ictalurus punctatus) were investigated in a 26-wk experiment. A purified basal diet alone or supplemented with 0.2 mg/kg selenium, 50 mg/kg vitamin E or both was fed to fingerling channel catfish in aquaria. Combined deficiencies of selenium and vitamin E caused suppressed growth, anemia, severe myopathy, exudative diathesis and death. Singular deficiencies of either selenium or vitamin E did not produce any of these deficiency signs. Catfish fed selenium-deficient diets with or without supplemental vitamin E had reduced glutathione peroxidase activity and elevated glutathione transferase activity in liver. Vitamin E deficiency in catfish caused elevated ascorbic acid-stimulated lipid peroxidation of hepatic microsomes, which was unaffected by selenium supplementation. The results indicate that there is a significant interaction between selenium and vitamin E in the nutrition of the channel catfish.
D000818:Animals; D001835:Body Weight; D005399:Fishes / Q000502:physiology*; D005921:Glomerulonephritis / Q000209:etiology; D005979:Glutathione Peroxidase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D006400:Hematocrit; D008054:Lipid Peroxides / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D008862:Microsomes, Liver / Q000378:metabolism; D009132:Muscles / Q000473:pathology; D009336:Necrosis; D012643:Selenium / Q000172:deficiency* / Q000502:physiology; D014810:Vitamin E / Q000502:physiology; D014811:Vitamin E Deficiency / Q000150:complications / Q000473:pathology / Q000503:physiopathology*
D008054:Lipid Peroxides; D014810:Vitamin E; D005979:Glutathione Peroxidase; D005982:Glutathione Transferase; D012643:Selenium