title: Inflammatory linear verrucous epidermal nevus (ILVEN) in a mother and her daughter.
abstract: Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare skin disease with characteristic clinical and histological changes. The approximately 100 cases so far reported include only one familial occurrence involving a woman and her nephew. We report the occurrence of typical ILVEN in a 47-year-old mother and her 17-year-old daughter. So far, no clear-cut genetic interpretation of this observation can be given. Apart from coincidence, various genetic explanations are considered, including X-linked inheritance with extreme lyonization.
mesh_terms: D000293:Adolescent; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D009506:Nevus / Q000235:genetics*; D012878:Skin Neoplasms / Q000235:genetics*