title: [Basement membranes as the regulatory system between epithelial cell connections and connective tissue].
abstract: Basement membranes develop by an interaction between epithelium and underlying mesenchymal. Basement membranes are to an great extend involved in the metabolic induced informational exchange between these 2 compartments. Informational selectivity is not only given with the construction of basement membranes. By redox systems like ascorbic acid/dehydroascorbic acid, preferentially located in basement membranes, the capability exists of scavenging free oxygen radicals on the border line between epithelia and connective tissue. This seems to be a very important factor in coupling the biorhythms between epithelia and connective tissue.
mesh_terms: D000136:Acid-Base Equilibrium; D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism; D001485:Basement Membrane / Q000033:anatomy & histology*; D002199:Capillary Permeability; D002450:Cell Communication; D002463:Cell Membrane Permeability; D003094:Collagen / Q000378:metabolism; D003238:Connective Tissue / Q000033:anatomy & histology*; D004727:Endothelium / Q000033:anatomy & histology; D004734:Energy Metabolism; D004848:Epithelium / Q000033:anatomy & histology; D005609:Free Radicals; D006801:Humans; D010084:Oxidation-Reduction; D010101:Oxygen Consumption
chemical_list: D005609:Free Radicals; D003094:Collagen; D001205:Ascorbic Acid
vernacular_title: Basalmembranen als Regulationssysteme zwischen epithelialen Zellverbänden und Bindegewebe.