Multifocal eosinophilic granuloma. Response of a patient to etoposide.
A 60-year-old man with a history of diabetes insipidus presented with a left groin mass, leg edema, and retroperitoneal adenopathy. Biopsy results of the involved lymph nodes were typical of eosinophilic granuloma. The patient was treated with etoposide and prednisone and had a complete regression of his lymphadenopathy and edema. This response suggests that etoposide may be a useful agent in the management of histiocytosis X.
D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005047:Etoposide / Q000627:therapeutic use*; D006801:Humans; D008220:Lymphography; D008297:Male; D008875:Middle Aged; D011034:Podophyllotoxin / Q000031:analogs & derivatives*; D014057:Tomography, X-Ray Computed
D005047:Etoposide; D011034:Podophyllotoxin