EsD in Negro and Caucasian populations: is the EsD5 a 'Caucasian allele'?
A total of 461 individuals, belonging to some Subsaharan populations (Beti, Bateke and Babenga Pygmies of Congo; Goun and Nago of Benin; Mbugu and Sango of the Central African Republic), and a sample of 231 individuals of the population of Rome (Italy) have been typed for red cell esterase D using conventional electrophoresis and isoelectric focusing. The Subsaharan populations showed a high variability of the frequency of the EsD2 allele (0.018-0.138) and the absence of the EsD5 allele which, on the contrary, reached a polymorphic frequency (0.017) in the Italian sample. These results suggest that the EsD5 allele has a Caucasian origin.
D000349:Africa; D000483:Alleles; D044383:Black People; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000097:blood / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology; D005006:Ethnicity; D005787:Gene Frequency; D006801:Humans; D011110:Polymorphism, Genetic; D012384:Rome; D044465:White People
D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase; C020118:ESD protein, human