Variation in sister-chromatid exchange among 106 members of the general U.K. population.
SCE scores of lymphocytes from 106 people revealed that the majority of background variation in SCE was between cells within individuals. Highly significant differences existed between individuals. Lesser, but still highly significant differences also existed between replicate cultures. Inter-individual variation was contributed to by each person's sex and their smoking habits. SCE frequency was not influenced by any of the other factors considered, age, drinking habits and diagnostic X-ray exposure of persons or lymphocyte number and proliferation rate in cultures.
D000367:Age Factors; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008214:Lymphocytes; D008297:Male; D012737:Sex Factors; D012854:Sister Chromatid Exchange / Q000187:drug effects; D013223:Statistics as Topic