title: Endogenous microbial dissemination following severe burns in rats.
abstract: This study suggests that damage to the intestinal lining, an important mechanical barrier against bacterial invasion, is the main factor leading to the dissemination of endogenous microbes. Reduced phagocytic activity of Kupffer cells and compromised opsonic function also appear to contribute to the process.
mesh_terms: D000818:Animals; D002056:Burns / Q000150:complications* / Q000276:immunology; D005353:Fibronectins / Q000276:immunology; D007413:Intestinal Mucosa / Q000276:immunology; D007422:Intestines / Q000382:microbiology*; D007728:Kupffer Cells / Q000276:immunology; D008099:Liver / Q000276:immunology; D008297:Male; D010587:Phagocytosis; D011552:Pseudomonas Infections / Q000209:etiology* / Q000276:immunology; D051381:Rats; D014946:Wound Infection / Q000209:etiology* / Q000276:immunology
chemical_list: D005353:Fibronectins