title: Hydrolysis of adenylyl(2'-5')adenosine in chick embryo sera.
abstract: Similar to adult chick sera in chick embryo sera the enzyme activity hydrolyzing the core of the dimer of A-5A - adenylyl(2' -5')adenosine is present. The enzyme activity possesses the same properties in both sera. Heating of the serum to 60 degrees C for 30 minutes does not affect the enzyme activity. A marked decrease in activity occurs after heating of the serum to above 65 degrees C. Hydrolysis of A2' p5' A in the serum is more efficient under alkaline conditions (pH 9-10) than at physiological pH 7.2-7.4.
mesh_terms: D000249:Adenosine Monophosphate / Q000031:analogs & derivatives* / Q000097:blood; D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D015226:Dinucleoside Phosphates; D005314:Embryonic and Fetal Development; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007700:Kinetics; D013816:Thermodynamics
chemical_list: D015226:Dinucleoside Phosphates; C031130:adenylyl-(2'-5')-adenosine; D000249:Adenosine Monophosphate