title: Follow-up studies in pattern VECP in demyelinating diseases in children.
abstract: Demyelinating disease in children is known to be relatively rare. We report three cases defined as Devic's disease, acute disseminated encephalomyelitis, and multiple sclerosis. Follow-up studies of pattern appearance-disappearance visual evoked cortical potentials (VECPs) and pattern reversal steady state VECPs were performed. Results showed delays of appearance-disappearance VECPs that improved to shorter latencies with the improvement of visual acuity; however, recovery of VECPs was found to be behind the recovery of subjective vision. On the other hand, steady-state VECPs showed no normal waveforms even when vision recovered. Recovery of steady-state VECPs was found to be far behind that of transient VECPs and vision.
mesh_terms: D000293:Adolescent; D002540:Cerebral Cortex / Q000503:physiopathology*; D002648:Child; D003711:Demyelinating Diseases / Q000503:physiopathology*; D005074:Evoked Potentials, Visual; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D014792:Visual Acuity