title: Epithelial ovarian cancer: do all metastases present similar chemosensitivity?
abstract: Three cases of advanced epithelial ovarian carcinoma Stage III-IV which could not be submitted to classical surgical and oncological treatment (BSO-TH) are presented. After a year of chemotherapy a complete remission was observed. Myometrial and myocervical micrometastases were found in a specimen from the hysterectomy, carried out during second-look, that was negative. These micrometastases, when they are present, apparently show a different chemosensitivity, as compared with other metastasis localization. The causes of this phenomenon are analyzed.
mesh_terms: D005260:Female; D006801:Humans; D007044:Hysterectomy; D008558:Melphalan / Q000627:therapeutic use; D009362:Neoplasm Metastasis; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D008558:Melphalan