Fever after cimetidine and ranitidine.
A 54-year-old bed-bound multiple sclerosis patient experienced fever, mental confusion, and marginal serum creatinine elevations after receiving cimetidine and subsequently ranitidine therapy. Fever and mental confusion recurred following a planned ranitidine challenge. We do not know whether a direct effect on the thermoregulatory center or a hypersensitivity reaction to the drugs was the mechanism of fever production in this patient.
D002927:Cimetidine / Q000009:adverse effects*; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011899:Ranitidine / Q000009:adverse effects*
D002927:Cimetidine; D011899:Ranitidine