[Oxidation of [1-14C]palmitoyl-CoA, [1-14C]acetyl-CoA and [2-14C]pyruvate in rabbit adrenal, liver and heart mitochondria under normal conditions and in acute stress].
The acute immobilized stress was studied for its effect on oxidation rate of [1-14C]palmitoyl-CoA, [1-14C]acetyl-CoA and [2-14C]pyruvate in mitochondria of the adrenals, liver and heart of rabbits. The stress effect on the energy metabolism of adrenals is associated with an increase of the rate of CO2 formation from pyruvate and with a decrease of the rate of CO2 formation from palmitoyl-CoA. Intensified oxidation of all substrates is observed in the heart mitochondria. The processes of beta-oxidation are more active in the liver. The data obtained evidence for differences in the mechanisms of energy metabolism reconstruction under acute stress in tissues with different functional specialization.
D000105:Acetyl Coenzyme A / Q000378:metabolism; D000208:Acute Disease; D000311:Adrenal Glands / Q000378:metabolism*; D000818:Animals; D004734:Energy Metabolism; D008297:Male; D008928:Mitochondria / Q000378:metabolism*; D008929:Mitochondria, Heart / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000378:metabolism*; D010084:Oxidation-Reduction; D010171:Palmitoyl Coenzyme A / Q000378:metabolism; D011773:Pyruvates / Q000378:metabolism; D011817:Rabbits; D013312:Stress, Physiological / Q000378:metabolism*
D011773:Pyruvates; D010171:Palmitoyl Coenzyme A; D000105:Acetyl Coenzyme A
Okislenie [1-14C]pal'mitoil-CoA, [1-14C]atsetil-CoA i [2-14C]piruvata v mitokhondriiakh nadpochechnikov, pecheni i serdtsa krolikov v norme i pri ostrom stresse.