title: Fluorescence response of acridine orange to changes in pH gradients across liposome membranes.
abstract: The influence that changes in proton distribution have on the fluorescence of acridine orange was examined using negatively charged liposomes. Our results indicate that at least two mechanisms are involved: distribution of the probe between the internal aqueous phase of the liposomes and the outside medium, and binding of the probe to the liposome membranes.
mesh_terms: D000165:Acridine Orange / Q000378:metabolism*; D005453:Fluorescence; D006863:Hydrogen-Ion Concentration; D008081:Liposomes / Q000378:metabolism*
chemical_list: D008081:Liposomes; D000165:Acridine Orange