[Comparative study of the biological properties of various bacterial polysaccharides].
It was shown that different polysaccharides markedly vary in their toxicity, exert a radioprotective effect when administered both 24 h and 1-4 h before irradiation, enhance and prolong the radioprotective action of S-containing radioprotective agents, and inhibit DNA synthesis in bone marrow which, in all appearance, plays a certain role in the mechanism of their radioprotective action.
D000818:Animals; D004247:DNA / Q000096:biosynthesis / Q000528:radiation effects; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006168:Guinea Pigs; D007958:Leukocyte Count / Q000187:drug effects / Q000528:radiation effects; D008297:Male; D051379:Mice; D011135:Polysaccharides, Bacterial / Q000494:pharmacology* / Q000633:toxicity; D011833:Radiation Injuries, Experimental / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000633:toxicity; D013997:Time Factors
D011135:Polysaccharides, Bacterial; D011837:Radiation-Protective Agents; D004247:DNA
Sravnitel'noe issledovanie biologicheskikh svoĭstv riada bakterial'nykh polisakharidov.