title: The use of the bivalve Mytilus edulis as a test organism for bioconcentration studies. II. The bioconcentration of two 14C-labeled chlorinated paraffins.
abstract: The bioconcentration of two 14C-labeled chlorinated paraffins (CP) has been studied in a flow-through test system using the common mussel Mytilus edulis. Both CPs showed a rapid uptake rate and the CP with C16 carbon chain and 34% chlorination had a bioconcentration factor (BCF) of about 7000 (fresh weight). The CP with a C12 carbon chain and 69% chlorination had a very high BCF of almost 140,000 which on a lipid weight basis corresponds to a BCF of around 8,000,000. The C12-CP showed a slow depuration rate in analogy with what has been observed earlier in fish. Radioactivity was recovered from both the fat and protein fractions after exposure to the C12-CP with a level in the protein of about two orders of magnitude lower than in the fat. It is concluded that studies with CPs so far reported indicate that short carbon chain/high chlorinated chlorinated paraffins are strongly bioaccumulating and persistent chemicals.
mesh_terms: D000818:Animals; D001711:Biotransformation; D049872:Bivalvia / Q000378:metabolism*; D002849:Chromatography, Gas; D005223:Fats / Q000378:metabolism; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism; D013997:Time Factors
chemical_list: D005223:Fats; D006843:Hydrocarbons, Chlorinated; D011506:Proteins