title: [Severe osteopenia in young children with hyperthyroidism. 2 cases].
abstract: The cases of 2 young children with Grave's disease and severe bone demineralization are reported. In one case, spontaneous fracture and a collapsed vertebra were noted. Increased serum alkaline phosphatase levels and normal 1.25-(OH)2D and 24-25 (OH)2D levels were observed when 25(OH)D levels were decreased. These anomalies, not described previously in young hyperthyroid children, should be kept in mind. Bone X-ray and calcium phosphorus metabolism investigations should be part of routine check-ups of young children with Grave's disease.
mesh_terms: D002118:Calcium / Q000097:blood; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000150:complications*; D008297:Male; D010024:Osteoporosis / Q000209:etiology* / Q000378:metabolism; D010710:Phosphates / Q000097:blood; D014807:Vitamin D / Q000378:metabolism
chemical_list: D010710:Phosphates; D014807:Vitamin D; D002118:Calcium
vernacular_title: Ostéopénie grave chez de jeunes enfants atteints d'hyperthyroïdie. Deux observations.