title: Relationship between basilar membrane tuning and hair cell condition.
abstract: Basilar membrane tuning characteristics were measured in 15 cats using laser interferometry. The experimental procedures introduced varying degrees of cochlear trauma. Variability from animal to animal was also observed in the characteristic frequency (CF) of tuning, the sensitivity at CF and lower frequencies, and the sharpness of tuning. The changes in the tuning characteristics of the basilar membrane are correlated with the extent of outer hair cell (OHC) damage. These observations lead to the conclusion that the tuning properties in the CF region are predominantly determined by the mechanical properties of the OHC and not the basilar membrane.
mesh_terms: D000818:Animals; D001489:Basilar Membrane / Q000502:physiology*; D001696:Biomechanical Phenomena; D002415:Cats; D003055:Cochlear Microphonic Potentials; D007758:Ear, Inner / Q000502:physiology*; D006198:Hair Cells, Auditory / Q000502:physiology*; D008954:Models, Biological; D010898:Pitch Perception / Q000502:physiology*