Borrelia-induced meningoradiculitis--two different forms of the disease.
The pattern of CSF cytological findings in the acute stage and after 10 days of antibiotic and steroid treatment was examined in 14 patients with meningoradiculitis due to an arthropode-transmitted infection with Borrelia duttoni (burgdorferi). At the acute onset of neurological symptoms, 12 patients revealed lymphocytic pleocytosis (cell count 50-500 X 10(6) cells/l) with numerous plasma cells (5-12% of the total cell count) and neutrophilic granulocytes (0.2-3.4%). 10-14 days after the onset of penicillin infusion and steroid treatment, cell count was reduced by at least 50% in 8 patients. Plasma cells then varied between 2 and 8%, whereas the neutrophilic granulocytes had disappeared. Two patients with slowly progressive neurological symptoms had a normal cell count, and inflammatory changes in CSF cytology were not observed.
D001899:Borrelia Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000145:classification / Q000635:transmission; D006801:Humans; D008581:Meningitis / Q000209:etiology*; D011843:Radiculopathy / Q000209:etiology*; D013987:Ticks; D013997:Time Factors