[Development and testing of an ointment base containing a complex emulsifier].
Using a hydrophilic and a lipophilic emulsifier the authors worked out a cream compound (having amphiphilic properties), which can be mixed with oil as well as with water. They convinced themselves that beyond the properties of the emulsifiers their ratio to each other is a crucial element in the development of the composition. They characterized changes in consistency when the composition was modified using rheological methods. In in vitro experiments they determined the influence of the base on the dissolution rate of the agent.
D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005079:Excipients / Q000032:analysis*; D009823:Ointment Bases / Q000032:analysis*; D010592:Pharmaceutic Aids / Q000032:analysis*; D012212:Rheology; D012995:Solubility; D014783:Viscosity
D005079:Excipients; D009823:Ointment Bases; D010592:Pharmaceutic Aids
Entwicklung und Prüfung einer Komplexemulgator enthaltenden Salbengrundlage.