Persistent disturbances of cognitive functions in patients with pseudotumor cerebri.
In a series of 20 consecutive patients with pseudotumor cerebri, five patients had a protracted course of the disease with complaints of persistent disturbances in learning and memory functions. Neuropsychological examination disclosed a light general intellectual impairment with most marked disturbances in verbal tests. After intensive medical treatment or ventriculo-atrial shunt operation, psychological re-examination showed improvement in the test results in accordance with the improvement of the patients' occupational and social situation. Cognitive dysfunction can be the result of a prolonged course of benign intracranial hypertension, and the term "benign" may be misleading in these cases. However, the intellectual impairment, even when long-standing, seems to be reversible in most patients after medical or surgical measures to lower the intracranial pressure.
D000086:Acetazolamide / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007858:Learning; D008297:Male; D008568:Memory; D008875:Middle Aged; D011559:Pseudotumor Cerebri / Q000188:drug therapy / Q000523:psychology*; D011581:Psychological Tests
D000086:Acetazolamide