title: [Electron microscopic microanalysis of prickle cell carcinoma, basaloma, malignant melanoma and normal skin].
abstract: EMMA has been used in Dermatology since 10 years. In 1981, Fisher established the Cu/Zn index as a parameter for the prognosis of malignant melanoma. We tested the EMMA technique as a means to determine the Cu/Zn index in basal cell carcinoma, squamous cell carcinoma, malignant melanoma, and normal skin. Our preliminary conclusions are: EMMA may be useful to determine the Cu/Zn index in skin tumors; it is possible to obtain useful data from tumors already fixed in paraffin; (c) the highest Cu/Zn index was found in normal skin, the lowest one in malignant melanoma.
mesh_terms: D002280:Basal Cell Carcinoma / Q000032:analysis* / Q000648:ultrastructure; D002294:Carcinoma, Squamous Cell / Q000032:analysis* / Q000648:ultrastructure; D003300:Copper / Q000032:analysis; D006801:Humans; D008545:Melanoma / Q000032:analysis* / Q000648:ultrastructure; D008854:Microscopy, Electron; D012867:Skin / Q000032:analysis* / Q000473:pathology / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000032:analysis* / Q000648:ultrastructure; D015032:Zinc / Q000032:analysis
chemical_list: D003300:Copper; D015032:Zinc
vernacular_title: Elektronenmikroskopische Mikro-Analyse (EMMA) von Spinaliom, Basaliom, malignem Melanom und normaler Haut.