Total body fluid volume determination based on urea kinetics in hemofiltration as an index of basal body weight in uremic patients.
Assuming that urea is distributed uniformly within the total body water, urea-space or total body fluid volume was determined in six uremic patients based on urea kinetics in hemofiltration. The total body fluid volume before hemofiltration was 36.0 +/- 3.6 L (61.8 +/- 2.6% BW) and after hemofiltration 32.5 +/- 3.4 L (59.3 +/- 2.8% BW), suggesting that the total body fluid volume was nearly normalized by hemofiltration. It is concluded that urea-space, easily measurable based on urea kinetics during hemofiltration, is useful in evaluating the fluid balance in patients undergoing artificial kidney therapy.
D001769:Blood; D001834:Body Water / Q000032:analysis*; D001835:Body Weight; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D014462:Ultrafiltration; D014508:Urea / Q000378:metabolism*; D014511:Uremia / Q000628:therapy*
D014508:Urea