title: [Biological characteristics of 3 new substrains of laboratory mice used in evaluating the quality of pertussis vaccines].
abstract: NFR/NM, NFS/NM inbred mice and M : CFLP random bred mice have been shown to possess immunobiological properties making them suitable for the evaluation of the quality of pertussis vaccines and for their standardization. NFS/NM mice are highly sensitive to the histamine-sensitizing factor, while M : CFLP mice are sensitive to the lienotoxic factor of pertussis vaccines. All these substrains of mice have sufficient fertility for their breeding under the conditions of a commercial breeding establishment.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D004353:Drug Evaluation, Preclinical; D005069:Evaluation Studies as Topic; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains / Q000502:physiology*; D010567:Pertussis Vaccine / Q000276:immunology; D011786:Quality Control; D012098:Reproduction
chemical_list: D010567:Pertussis Vaccine
vernacular_title: Biologicheskie kharakteristiki trekh novykh subliniĭ laboratornykh mysheĭ, ispol'zuemykh pri otsenki kachestva kokliushnykh vaktsin.