title: Proline biosynthesis encoded by the noc and occ loci of Agrobacterium Ti plasmids.
abstract: Octopine or nopaline Ti plasmids, or clones encoding their occ or noc loci, allowed proline auxotrophs of Agrobacterium tumefaciens to utilize the appropriate arginyl opine as a proline substitute. Arginine and ornithine substituted for proline only if the occ or noc loci were induced or made constitutive by mutation. These results support a report demonstrating a Ti plasmid-encoded activity in A. tumefaciens which cyclizes ornithine to proline.
mesh_terms: D001120:Arginine / Q000031:analogs & derivatives / Q000378:metabolism; D005796:Genes; D005798:Genes, Bacterial; D009952:Ornithine / Q000378:metabolism; D010957:Plasmids; D011392:Proline / Q000096:biosynthesis*; D012231:Rhizobium / Q000235:genetics*
chemical_list: C008666:nopaline; C005394:octopine; D001120:Arginine; D011392:Proline; D009952:Ornithine