[Protective effect of phosphatidylcholine liposomes in experimental toxic hepatitis].
Level of fructose-1-monophosphate aldolase was decreased in blood serum after administration of phosphatidyl choline-containing liposomes into male rats with experimental toxic hepatitis caused by treatment with hepatotropic poison CCl4 at a dose of 0.25 ml/100 g of body mass. The rate of the aldolase level normalization depends on composition of liposomes as well as on the pathway of their administration.
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000201:enzymology; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000517:prevention & control*; D005634:Fructose-Bisphosphate Aldolase / Q000097:blood*; D008081:Liposomes / Q000008:administration & dosage*; D008297:Male; D010713:Phosphatidylcholines / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D051381:Rats
D008081:Liposomes; D010713:Phosphatidylcholines; D005634:Fructose-Bisphosphate Aldolase
Zashchitnoe deĭstvie fosfatidilkholinovykh liposom pri éksperimental'nom toksicheskom gepatite.