[Morphology of the adrenal cortex in the adrenogenital syndrome with salt loss].
Adrenals were studied in 17 children with adrenogenital syndrome with a salt loss. Adrenals from 9 children who died from mechanical asphyxia served as control. Adrenal weight, the width of adrenal zones were measured, the volumes of nuclei and nucleoli were calculated after having been drawn on millimeter paper. The dilatation of both fascicular and reticular zones, the persistence of a fetal zone were found. Nuclear polymorphism, hyperchromatism and in 2 cases-mitotic figures were observed in the fascicular zone. An increase of nuclear and nucleolar volume is noted in cells of glomerular and fascicular zones. The zones of an increased functional activity (inner part of a glomerular zone and external part of a fascicular one) are distinguished. Alterations if cortex cells are the evidence of their hypertrophy and, to a lesser extent, their hyperplasia.
D000302:Adrenal Cortex / Q000473:pathology*; D000311:Adrenal Glands / Q000473:pathology; D000312:Adrenal Hyperplasia, Congenital / Q000378:metabolism / Q000473:pathology*; D001237:Asphyxia / Q000473:pathology; D002466:Cell Nucleolus / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000209:etiology*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009318:Natriuresis; D045283:Natriuretic Agents / Q000502:physiology; D009929:Organ Size; D011015:Pneumonia, Aspiration / Q000473:pathology; D012084:Renin-Angiotensin System
D045283:Natriuretic Agents
Morfologiia kory nadpochechnikov pri adrenogenital'nom sindrome s potereĭ soli.