Serum ferritin in acquired immune deficiency syndrome.
Ferritin has been linked to a variety of immunosuppressive effects on cell-mediated immunity. Therefore, serum ferritin was measured by radioimmunoassay in patients with acquired immune deficiency syndrome (AIDS), AIDS-related complex (ARC) and healthy heterosexual men. 13 of 15 patients with AIDS and 4 of 15 with ARC had ferritin levels greater than 300 micrograms/dl. This study suggests that the levels of serum ferritin increase with the progression of immune deficiency and might play a role in the pathogenesis of cell-mediated immune deficiency in AIDS.
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood* / Q000150:complications; D005293:Ferritins / Q000097:blood*; D006716:Homosexuality; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000145:classification / Q000276:immunology; D008297:Male; D011863:Radioimmunoassay; D012016:Reference Values
D005293:Ferritins