title: Sporogenesis and toxin A production by Clostridium difficile.
abstract: The kinetics of spore production by Clostridium difficile were not paralleled by release of C. difficile toxin A in vitro. Toxin A was not found to be associated with either purified whole spores or spore coats. Residual traces of toxin A detected in spore contents were almost certainly derived from contaminating vegetative cell debris. Thus, toxin A is unlikely to be a spore constituent or associated with sporogenesis.
mesh_terms: D001427:Bacterial Toxins; D003013:Clostridium / Q000378:metabolism / Q000502:physiology*; D004768:Enterotoxins / Q000096:biosynthesis*; D007700:Kinetics; D013171:Spores, Bacterial / Q000502:physiology; D014465:Ultrasonics
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; C041348:tcdA protein, Clostridium difficile