Hereditary monocyte esterase deficiency.
An inherited cytochemical staining abnormality of monocytes is described, affecting members of three generations of one family. alpha-Naphthyl acetate and alpha-naphthyl butyrate esterase staining reactions have been consistently negative in 95% of the monocytes of the propositus and her son and in 60-70% of the monocytes in two of four grandchildren.
D000368:Aged; D002265:Carboxylic Ester Hydrolases / Q000172:deficiency; D004950:Esterases / Q000097:blood*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000201:enzymology*; D009000:Monocytes / Q000201:enzymology*; D009283:Naphthol AS D Esterase / Q000172:deficiency; D010375:Pedigree; D010587:Phagocytosis
D004950:Esterases; D009283:Naphthol AS D Esterase; D002265:Carboxylic Ester Hydrolases; C021855:naphthylbutyrate esterase