title: Recombinant alpha-2 interferon for treatment of hairy cell leukemia without prior splenectomy.
abstract: Splenectomy has been the traditional initial treatment for hairy cell leukemia, with medical treatment reserved for resistant disease. This report describes two patients treated with recombinant alpha-2 interferon without prior splenectomy. Both patients responded well to interferon therapy. Alpha-2 interferon may become the initial therapy of choice for hairy cell leukemia.
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D007943:Leukemia, Hairy Cell / Q000097:blood / Q000628:therapy*; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011994:Recombinant Proteins / Q000627:therapeutic use*; D013156:Splenectomy
chemical_list: D007370:Interferon Type I; D011994:Recombinant Proteins