title: [Biological properties of glutamin-(asparagin-)ase from Pseudomonas boreopolis 526].
abstract: Glutamine(asparagine)ase from Ps. boreopolis 526 has an antineoplastic effect on lymphoid leukemia P-388. The enzyme half-life in the mouse serum is 8.5 hours. Glutamine(asparagine)ase has no cross-antigenicity with L-asparaginase from E. coli (Bayer, FRG). Specific antibodies against L-asparaginase (Bayer, FRG) do not influence the activity of glutamine(asparagine)ase.
mesh_terms: D000581:Amidohydrolases / Q000097:blood / Q000276:immunology / Q000627:therapeutic use*; D000818:Animals; D000970:Antineoplastic Agents / Q000097:blood / Q000276:immunology / Q000627:therapeutic use*; D006207:Half-Life; D007941:Leukemia P388 / Q000188:drug therapy*; D007942:Leukemia, Experimental / Q000188:drug therapy*; D051379:Mice; D011549:Pseudomonas / Q000201:enzymology*; D011817:Rabbits
chemical_list: D000970:Antineoplastic Agents; D000581:Amidohydrolases; C020654:glutamin-(asparagin-)ase
vernacular_title: Biologicheskie svoĭstva glutamin(asparagin)azy iz Pseudomonas boreopolis 526.