title: Radiographic assessment of laryngeal reflexes in ketamine-anesthetized cats.
abstract: The competence of the laryngeal closure reflexes of cats anesthetized with ketamine was assessed. Radiographic evaluations of the respiratory and digestive tracts were made after colloidal barium suspension was instilled into the pharynges of conscious and ketamine-anesthetized cats. There was a significant ketamine dose-related response of spread of contrast medium into the supraglottic laryngeal area and into the stomach 2 minutes after contrast medium was instilled into the pharynx (P less than 0.05). Cats did not aspirate contrast medium into the lower respiratory tract. Three ketamine-anesthetized cats aspirated contrast medium into the subglottic area of the larynx, and 2 of these cats also aspirated the material into the cranial part of the trachea. This material was coughed up and swallowed within 5 minutes. Transit time of contrast medium into the stomach seemed to be increased in 11 of the 15 cats given the larger dosages of ketamine (24, 36, 48 mg/kg of body weight), compared with that in conscious cats and those given ketamine at 12 mg/kg. Competent laryngeal protective reflexes in cats can be maintained with ketamine anesthesia. Contrast radiography could be used as a diagnostic aid in ketamine-anesthetized cats suspected of laryngeal reflex abnormalities.
mesh_terms: D000818:Animals; D002415:Cats; D003287:Contrast Media; D005260:Female; D007649:Ketamine / Q000494:pharmacology*; D007830:Larynx / Q000000981:diagnostic imaging / Q000187:drug effects / Q000502:physiology*; D008297:Male; D011859:Radiography; D012018:Reflex / Q000187:drug effects*
chemical_list: D003287:Contrast Media; D007649:Ketamine