title: [Primary-multiple cancer of the breast (from the data of the Chelyabinsk Regional Oncology Dispensary)].
abstract: 102 cases of primary multiple breast cancer (bilateral and multicentric tumors-61; synchronous tumors of the breast and genitals-12) were treated at the Regional Oncological Dispensary in Chelyabinsk in 1976-83. Tumors generally occurred in patients of the 40-50 years bracket at an interval of 5.2 +/- 0.3 years. A certain role in the pathogenesis of primary multiple breast cancer was played by reproductive function as well as previous treatment modality (gamma-therapy, cytostatic treatment and ovariectomy).
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006728:Hormones / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000209:etiology* / Q000503:physiopathology; D010052:Ovariectomy / Q000009:adverse effects; D012098:Reproduction
chemical_list: D006728:Hormones
vernacular_title: Pervichno-mnozhestvennyĭ rak molochnykh zhelez (po materialam Cheliabinskogo oblastnogo onkologicheskogo dispansera).