[Comparison of the leukopoietic effect of NeyTumorin, NeyThymun and 2-cyanethyl-carbamide].
In an animal experiment (65 Wistar rats) NeyTumorin-Sol and NeyThymun-Sol f + k with 2-Cyanethyl-carbamide were examined in order to determine their leukopoietic and lymphopoietic effect respectively, which proved nearly equal and significant in all preparations. The maximum in the number of leukocytes with a medium elevation by a factor of 1.6 was found between the 14th and 25th day. The lymphopoiesis was especially stimulated with a medium elevation of the number of cells by a factor of 2.9. A repeated application didn't lead to an advantage compared with a single application. The combination of two different preparations resulted in the same or even worse findings compared with a separate administration of the various substances under examination.
D000818:Animals; D006410:Hematopoiesis / Q000187:drug effects*; D007958:Leukocyte Count / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013268:Stimulation, Chemical; D013949:Thymus Extracts / Q000494:pharmacology*; D013997:Time Factors; D014020:Tissue Extracts / Q000494:pharmacology*; D014508:Urea / Q000031:analogs & derivatives* / Q000494:pharmacology
D013949:Thymus Extracts; D014020:Tissue Extracts; C033054:2-cyanoethylurea; C041301:neytumorin; D014508:Urea; C049481:neythymun
Vergleich der leukopoetischen Wirkung von NeyTumorin, NeyThymun und 2-Cyanethylharnstoff.