[Analysis of chromosome aberrations on the basis of synaptonemal complexes in the offspring of mice irradiated with gamma-rays].
Electron-microscopic analysis of synaptonemal complexes (SC) spread on the surface of hypophase was carried out to study chromosome rearrangements in sterile and semisterile F1 offsprings of mice exposed to gamma-radiation at a dose of 5 Gy. Chromosome rearrangements were microscopically scored at diakinesis - metaphase I in the same animals. SC analysis at pachytene revealed chromosome rearrangements in 63% spermatocytes. Analysis of chromosomes at diakinesis - metaphase I in the same animals only revealed chromosome rearrangements in 32% cells. SC analysis permits detecting chromosome rearrangements undetectable at diakinesis - metaphase I.
D000818:Animals; D002869:Chromosome Aberrations / Q000528:radiation effects*; D005260:Female; D005720:Gamma Rays; D007248:Infertility, Male / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D008297:Male; D008540:Meiosis / Q000528:radiation effects*; D051379:Mice; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011833:Radiation Injuries, Experimental / Q000235:genetics* / Q000473:pathology; D013573:Synaptonemal Complex / Q000528:radiation effects*; D013737:Testis / Q000648:ultrastructure
Analiz khromosomnykh perestroek na osnove sinaptonemnykh kompleksov u potomkov mysheĭ, obluchennykh gamma-luchami.