title: An investigation of the effectiveness of bupivacaine applied to the abdominal wall and fallopian tubes in reducing pain after laparoscopic tubal ligation.
abstract: Sixty women having laparoscopic sterilisation performed under general anaesthesia were randomly allocated to one of two groups. Intraoperatively, one group had bupivacaine applied topically to the fallopian tubes and injected into the skin wounds, while the other group received no local anaesthetic. A double-blind investigation utilising a visual analogue scale failed to demonstrate a statistically significant difference in postoperative pain between the two groups. In both groups there was a significant reduction in mean pain scores between 1/2 and 7 hours, but there was no further reduction between 7 hours and 17 hours. At 7 hours, only 10% of patients scored their pain as 3 or greater (out of a possible 10). It is concluded that the use of bupivacaine as described is not a useful adjuvant to general anaesthesia and that the low incidence of even moderate pain at 7 hours confirms the view that these patients are suitable for management in the day-stay unit.
mesh_terms: D002045:Bupivacaine / Q000627:therapeutic use*; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D010149:Postoperative Pain / Q000188:drug therapy*; D011897:Random Allocation; D013246:Sterilization, Tubal
chemical_list: D002045:Bupivacaine