title: Acid phosphatase activity in soleus and plantaris muscle fibres of normal and dystrophic hamsters. A quantitative histochemical study.
abstract: The activity of acid phosphatase in skeletal muscle fibres of the plantaris and soleus of normal and dystrophic male hamsters was quantified using a histochemical post-coupling semipermeable membrane technique. Although the absolute levels of activity were found to vary widely from one animal to another, the ratio of the mean activities in the two muscles in each animal was virtually constant. In normal muscles, the ratio was about 0.73 and in dystrophic muscles, about 0.77. The activity in plantaris muscle fibres was always significantly lower than that in the corresponding soleus fibres, and in normal fibres compared to dystrophic ones. Another difference was that in normal fibres the mean activity declined to a constant level in mature animals older than about 3 months. In contrast, the activity in dystrophic muscles appeared to fall exponentially throughout life. The functional significance of these findings is discussed.
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000367:Age Factors; D000818:Animals; D006224:Cricetinae; D006651:Histocytochemistry; D008297:Male; D009132:Muscles / Q000201:enzymology*; D009137:Muscular Dystrophy, Animal / Q000201:enzymology*
chemical_list: D000135:Acid Phosphatase