title: [Changes in the permeability of vesicules from isolated apical membranes of rabbit small intestine epitheliocytes to K+, Na+, H+ during Ca-activated lipolysis].
abstract: pH-dependence of Ca2+-activated hydrolysis of self phospholipids was studied in vesicles from the apical epitheliocyte membranes of the rabbit small intestine. It was shown that lipolysis had pH optimum at 7.0 and involved phospholipases A2 and A1 (or lysophospholipases). Marked changes in vesicle permeability for cations are observed during 40-50% phospholipid hydrolysis.
mesh_terms: D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D002463:Cell Membrane Permeability; D006859:Hydrogen / Q000378:metabolism; D066298:In Vitro Techniques; D007421:Intestine, Small / Q000166:cytology / Q000378:metabolism*; D008066:Lipolysis / Q000187:drug effects*; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011817:Rabbits; D012964:Sodium / Q000378:metabolism
chemical_list: D008563:Membrane Lipids; D010743:Phospholipids; D006859:Hydrogen; D012964:Sodium; D011188:Potassium; D002118:Calcium
vernacular_title: Izmeneniia pronitsaemosti vezikul iz izolirovannykh apikal'nykh membran épiteliotsitov tonkoĭ kishki krolika dlia K+, Na+, H+ pri Ca-aktiviruemom lipolize.