Eosinophilic granulomatous pneumonia in a dog.
An eosinophilic granulomatous pneumonia is described in a German shepherd dog. On thoracic radiographs and at post mortem examination disseminated pulmonary tumour-like nodules had been seen. Histologically the nodules consisted of macrophages, eosinophils, plasma cells and occasionally giant cells. In plasma cells and macrophages, large amounts of immunoglobulin G and immunoglobulin M could be demonstrated. An aetiology could not be determined, but vasculitis and cytology made an allergic reaction of type 1 and, or, type 3 most likely. The classification of pulmonary infiltration with eosinophilia (PIE-syndrome) is discussed.
D000818:Animals; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D004285:Dogs; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D011657:Pulmonary Eosinophilia / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D011859:Radiography