title: [Asbestos carcinogenesis from clinical and hypothetical viewpoints].
abstract: On the basis of a case of mesothelioma of the pleura in a 28-year-old female who among our patients had the longest survival time after establishment of the diagnosis (31 months) the authors adopt a definite attitude to the problems of asbestosis. It can be regarded as ascertained that after asbest exposition a systemic contamination of the organism occurs. Apart from the inhalative intake further possibilities of the asbest fibre incorporation and the elimination are referred to. As to the cancerogenesis of asbest-induced malignomas the existing theories appear at present still insufficient; analogies to Virchow's irritation theory are possible in the serosa tumours.
mesh_terms: D000328:Adult; D001194:Asbestos / Q000009:adverse effects*; D001706:Biopsy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D008654:Mesothelioma / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009784:Occupational Diseases / Q000473:pathology; D010994:Pleura / Q000473:pathology; D010997:Pleural Neoplasms / Q000473:pathology*; D012306:Risk
chemical_list: D001194:Asbestos
vernacular_title: Zur Asbestkanzerogenese aus klinischer und hypothetischer Sicht.