title: Thiol proteins in chromatin.
abstract: Total half-cystine residues in proteins of pig liver chromatin have been measured. About half of them are present in the reduced state. Thiol groups of non-histone chromatin proteins, which amount to about 40 nmol/mg of protein, are preferentially located in chromatin fragments which are more easily solubilised either by DNAse I or by DNAse II. The data obtained are compatible with an involvement of SH and SS groups in chromatin structure and function.
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002843:Chromatin / Q000032:analysis*; D002868:Chromosomal Proteins, Non-Histone / Q000032:analysis; D003553:Cystine / Q000032:analysis; D003850:Deoxyribonuclease I; D004706:Endodeoxyribonucleases; D008099:Liver / Q000032:analysis; D009698:Nucleoproteins / Q000032:analysis*; D013438:Sulfhydryl Compounds / Q000032:analysis; D013552:Swine
chemical_list: D000596:Amino Acids; D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D009698:Nucleoproteins; D013438:Sulfhydryl Compounds; D003553:Cystine; D004706:Endodeoxyribonucleases; D003850:Deoxyribonuclease I; C019329:deoxyribonuclease II