title: An optical and electron microscopy study of materials implanted in the rat middle ear. II. A bioactive glass ceramic.
abstract: The bioactive glass Ceravital is rapidly covered by a fibrous encapsulating layer when placed in the rat middle ear. In addition, the surface of the glass becomes gradually modified from purely a silicate to a phosphosilicate. It is suggested that this phosphosilicate layer acts as a reservoir for the gradual mineralization of the encapsulating collagenous fibrils, resulting eventually in the formation of a strong bony bond.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D004432:Ear, Middle; D005898:Glass; D008855:Microscopy, Electron, Scanning; D019736:Prostheses and Implants; D051381:Rats; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials