Intravenous self-administration of (-)-cathinone and 2-amino-1-(2,5-dimethoxy-4-methyl)phenylpropane in rhesus monkeys.
The reinforcing effects of (-)-cathinone, a pharmacologically active ingredient of khat, and 2-amino-1-(2,5-dimethoxy-4-methyl)phenylpropane ((STP) (DOM)), a hallucinogenic psychotomimetic, were studied by intravenous self-administration experiments in rhesus monkeys. Among the experiments described in this paper, the result of continuous self-administration of (-)-cathinone was briefly reported elsewhere. T. Yanagita, Studies on Cathinones, NIDA Research Monograph 27, Proceedings of 41st Annual Scientific Meeting of the Committee on Problems of Drug Dependence, 1979, pp. 326-327.
D004290:DOM 2,5-Dimethoxy-4-Methylamphetamine / Q000494:pharmacology*; D000470:Alkaloids / Q000494:pharmacology*; D000662:Amphetamines / Q000494:pharmacology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D002490:Central Nervous System / Q000187:drug effects*; D003042:Cocaine / Q000494:pharmacology; D005795:Generalization, Stimulus; D007275:Injections, Intravenous; D008253:Macaca mulatta; D012054:Reinforcement, Psychology; D012646:Self Administration; D019966:Substance-Related Disorders
D000470:Alkaloids; D000662:Amphetamines; D004290:DOM 2,5-Dimethoxy-4-Methylamphetamine; C023665:cathinone; D003042:Cocaine