[Expression of virus-specific functions in 3-methylcholanthrene-induced leukemia in rats].
It was isolated and identified MR-Le virus from Wistar rats with myelogenous leukemia. The comparison of isolated in vivo and in vitro MR-Le virus with endogenous oncovirus RaLV in protein profile as well as results of molecular hybridization pointed out that RaLV did not participate in the induction of MR leukemia. The question about the role of MR-Le virus in the etiology of MR leukemia is opened now.
D000818:Animals; D002460:Cell Line; D002472:Cell Transformation, Viral; D002478:Cells, Cultured; D006224:Cricetinae; D004259:DNA-Directed DNA Polymerase / Q000097:blood; D004591:Electrophoresis, Polyacrylamide Gel; D007942:Leukemia, Experimental / Q000097:blood / Q000139:chemically induced / Q000382:microbiology*; D008748:Methylcholanthrene; D009368:Neoplasm Transplantation; D010455:Peptides / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D012190:Retroviridae / Q000032:analysis / Q000302:isolation & purification; D013045:Species Specificity; D014764:Viral Proteins / Q000032:analysis; D014771:Virion / Q000032:analysis / Q000302:isolation & purification
D010455:Peptides; D014764:Viral Proteins; D008748:Methylcholanthrene; D004259:DNA-Directed DNA Polymerase
Ekspressiia virusspetsificheskikh funktsiĭ pri leĭkoze u krys, indutsirovannom 3-metilkholantrenom.