title: Antifertility effects of embelin in male rats.
abstract: Embelin, extracted from Embelia ribes Burm. berries, altered the testicular histology and glycogen, gametogenic counts and accessory sex gland fructose at the dose levels 0.3, 0.4 and 0.5 mg/kg body weight administered subcutaneously for 35 days. The compound is suggested to possess antiandrogenic activity.
mesh_terms: D000726:Androgen Antagonists; D000818:Animals; D016227:Benzoquinones; D003272:Contraceptive Agents, Male; D005298:Fertility / Q000187:drug effects*; D005632:Fructose / Q000378:metabolism; D005837:Genitalia, Male / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D006003:Glycogen / Q000378:metabolism; D008297:Male; D011809:Quinones / Q000494:pharmacology*; D051381:Rats; D012708:Sertoli Cells / Q000473:pathology; D013091:Spermatogenesis / Q000187:drug effects; D013737:Testis / Q000187:drug effects / Q000378:metabolism / Q000473:pathology
chemical_list: D000726:Androgen Antagonists; D016227:Benzoquinones; D003272:Contraceptive Agents, Male; D011809:Quinones; D005632:Fructose; D006003:Glycogen; C010945:embelin