title: Central nervous system repair and nerve cell cultures.
abstract: Is anatomical and functional repair following injury or disease in the adult brain and spinal cord possible, and to what extent? Current evidence concerning neuronal plasticity of mature neurons suggests that opportunities may exist provided the variables are understood. Highly informative are the cellular and molecular processes regulated, in the mature CNS, by growth-promoting molecules directed to neurons. In this field neuronal cell culture methodology has proven to be indispensable and its application may in the future contribute significantly to the development of novel therapeutical strategies.
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology; D001930:Brain Injuries / Q000503:physiopathology* / Q000628:therapy; D002478:Cells, Cultured; D004594:Electrophysiology; D004622:Embryo, Mammalian; D051379:Mice; D009414:Nerve Growth Factors / Q000502:physiology; D009416:Nerve Regeneration; D009473:Neuronal Plasticity; D009474:Neurons / Q000502:physiology*
chemical_list: D009414:Nerve Growth Factors