title: Analysis of survival-curve data for heat plus irradiation in terms of the multitarget, multitarget with initial slope, and alpha, beta equations.
abstract: Survival values have been computed for heat plus radiation data using the three most common radiation survival models: multitarget, multitarget with initial slope, and linear quadratic. By chi 2 analysis, all three models provide an equally good fit to the experimental data. When the survival values are compared, the linear quadratic model provides a slightly better fit in the shoulder region, while the multitarget models provide a slightly better fit in the exponential region.
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000528:radiation effects; D002477:Cells / Q000528:radiation effects*; D006224:Cricetinae; D003412:Cricetulus; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006358:Hot Temperature; D008433:Mathematics; D010053:Ovary / Q000166:cytology