Metabolism of glycoproteins in cultured retinal pigment epithelium.
The turnover and migration of synthesized glycoproteins in the cultured retinal pigment epithelium have been studied. Quantitative study indicated that half-time of 3H-fucosylglycoproteins was 11.6 days. Autoradiography was performed several times after incubation of 3H-fucose. Retinal pigment epithelium constantly synthesized glycoproteins and released them into the basal extracellular material. Possible functions of the glycoproteins are discussed.
D000818:Animals; D001345:Autoradiography; D002478:Cells, Cultured; D002642:Chick Embryo; D005643:Fucose / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism*; D006207:Half-Life; D006651:Histocytochemistry; D008854:Microscopy, Electron; D010857:Pigment Epithelium of Eye / Q000378:metabolism*
D006023:Glycoproteins; D005643:Fucose