title: Left predominant coronary circulation in patients with valvular aortic stenoses.
abstract: This study was conducted to examine whether a correlation exists between the incidence of aortic stenosis and predominant left coronary perfusion. Therefore, coronary angiograms of 77 patients with mitral stenosis (Group 1), 50 patients with combined mitral valve disease and pure mitral insufficiency (Group 2), 61 patients with aortic insufficiency with or without mitral valve disease (Group 3), 49 patients with pure aortic stenosis (Group 4), and 69 patients with combined aortic valve disease and aortic stenosis with concomitant mitral valve disease (Group 5) were reviewed. Group 6 consisted of 20 patients with coronary heart disease. A statistically significant accumulation of left coronary circulation was found in patients with pure aortic stenosis (Group 4) (33%) as well as in patients with combined aortic valve disease (19%). The frequency of predominant left coronary circulation was comparable in all other patients (Group 1: 8%; Group 2: 10%; Group 3: 8%; Group 6: 7.5%). Thus, the presence of left predominance in a diagnostic coronary arteriogram performed in a patient with aortic stenosis could be a clue that the aortic stenosis is congenital.
mesh_terms: D000328:Adult; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000503:physiopathology; D001024:Aortic Valve Stenosis / Q000503:physiopathology*; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology*; D003331:Coronary Vessels / Q000473:pathology; D006349:Heart Valve Diseases / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve; D008944:Mitral Valve Insufficiency / Q000503:physiopathology; D008946:Mitral Valve Stenosis / Q000503:physiopathology