Isoforms of the phosphorylatable myosin light chain in arterial smooth muscle.
Two isoforms of the phosphorylatable myosin light chain of arterial smooth muscle have been identified, at proportions of 15 and 85%. The isoforms have similar tryptic peptide maps and can be mono-, di- and triphosphorylated. In intact or homogenized muscle, monophosphorylation and, to a small degree, diphosphorylation occur, whereas in isolated actomyosin diphosphorylation and triphosphorylation are manifested. Serine and threonine residues are phosphorylated in all three systems, but the ratio of phosphothreonine to phosphoserine is much higher in actomyosin than in muscle.
D000818:Animals; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D009218:Myosins; D010750:Phosphoproteins; D010766:Phosphorylation; D010768:Phosphoserine / Q000378:metabolism; D010769:Phosphothreonine / Q000378:metabolism; D013552:Swine
D010750:Phosphoproteins; D010769:Phosphothreonine; D010768:Phosphoserine; D009218:Myosins