[Effect of immunosorption on the functional state of immunocompetent cells].
The effect of immunosorption on the state of the membranes of immunocompetent cells playing an important role in numerous links of pathogenesis of disease was studied in 11 patients with bronchial asthma (atopic form). Two biophysical methods were employed: a fluorescent probe (a chlorotetracycline probe) and hemiluminiscence. A preliminary study showed noticeable changes in the state of cell membranes in patients with atopic bronchial asthma and aggravation of pathological changes caused by a specific allergen. Extracorporal immunosorption produced a positive effect on the state of the membranes of immunocompetent cells and a decrease in their sensitivity to a specific allergen in patients with the atopic form of bronchial asthma.
D001249:Asthma / Q000097:blood / Q000209:etiology / Q000628:therapy*; D002462:Cell Membrane / Q000276:immunology; D002751:Chlortetracycline / Q000494:pharmacology; D003470:Culture Media; D003888:Desensitization, Immunologic; D004391:Dust / Q000009:adverse effects; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000494:pharmacology; D006464:Hemoperfusion; D006801:Humans; D066298:In Vitro Techniques; D008163:Luminescent Measurements; D009000:Monocytes / Q000276:immunology* / Q000648:ultrastructure; D011058:Pollen
D003470:Culture Media; D004391:Dust; D005456:Fluorescent Dyes; D002751:Chlortetracycline
Vliianie immunosorbtsii na funktsional'noe sostoianie immunokompetentnykh kletok.