Silicotic lymph node lesions in non-occupationally exposed lung carcinoma patients.
The report deals with a series of peribronchial and mediastinal lymph node silicotic lesions, which were histologically and histochemically typical, in patients with bronchogenic cancer without any form of occupational dust exposure. The presence of a significant quantity of quartz was confirmed in the lesions by the use of backscatter electron imaging analysis, X-ray mapping and X-ray spectrometry. The lymph node lesions observed were actually silicotic in nature and had possible epidemiologic implications. There is a need for further investigations on larger series of cases to evaluate the incidence of the phenomenon and correlations between lung changes and lymph node lesions.
D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D001980:Bronchi / Q000473:pathology; D002283:Carcinoma, Bronchogenic / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D004577:Electron Probe Microanalysis; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008482:Mediastinum / Q000473:pathology; D008875:Middle Aged; D011791:Quartz / Q000032:analysis; D012829:Silicosis / Q000473:pathology*; D013052:Spectrometry, X-Ray Emission
D011791:Quartz