Epidemiology of chlamydial eye diseases in a mixed rural/urban population of West Germany.
4260 conjunctival specimens of 2850 outpatients with keratoconjunctivitis of presumed infectious etiology were studied. Two thousand six hundred sixty-eight specimens (63%) revealed growth of bacteria, and 80 (2%) growth of fungi. One hundred ninety-nine specimens (5%) were McCoy cell culture or direct stain (monoclonal antibody or Giemsa) positive for Chlamydia trachomatis. two patients had a C. psittaci infection (ELISA techniques). In patients with keratoconjunctivitis of bacterial etiology, overall incidence of McCoy cell culture-proven chlamydial infections was 7%; in the 20 to 30-year age group it was 12.5%. Simultaneous infections of chlamydiae and other bacteria were seen in 34 patients. Since sensitive and specific tests to diagnose chlamydial infections are available, ophthalmologists may be able to prevent these infections by agent-specific antibiotic therapy.
D000328:Adult; D001424:Bacterial Infections; D002690:Chlamydia Infections / Q000188:drug therapy; D002692:Chlamydia trachomatis; D004917:Erythromycin / Q000009:adverse effects / Q000627:therapeutic use; D005860:Germany, West; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007637:Keratoconjunctivitis / Q000453:epidemiology / Q000209:etiology*; D012424:Rural Population; D012923:Social Class; D013752:Tetracycline / Q000627:therapeutic use; D014505:Urban Population
D004917:Erythromycin; D013752:Tetracycline