title: Failure of naloxone to reduce self-injurious behavior in two developmentally disabled females.
abstract: Three doses of Naloxone (0.1, 0.2 and 0.4 mg.) were compared to treatment with saline in a double-blind crossover design. Neither of the two female subjects altered their rate of self-injurious behavior as a result of treatment. The present results suggest that naloxone does not reduce self-injurious behavior in all individuals.
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000534:rehabilitation*; D008875:Middle Aged; D009270:Naloxone / Q000627:therapeutic use*; D012652:Self Mutilation / Q000150:complications / Q000188:drug therapy*
chemical_list: D009270:Naloxone