Influence of Anisotes trisulcus and Crepis rueppellii extracts on sites of bile formation in the rat.
Anisotes trisulcus and Crepis rueppellii, two medicinal plants from Yemen, have been investigated for their hepatobiliary properties. A study of their choleretic effect and of sites of bile formation was carried out in the rat, by evaluation of bile flow, bile acids output and 14C-erythritol clearance. The data suggest that both extracts of these plants induce hypercholeresis, but Anisotes would stimulate the bile acid-dependent fraction and Crepis the bile acid-independent fraction.
D000818:Animals; D001646:Bile / Q000187:drug effects* / Q000378:metabolism; D001647:Bile Acids and Salts / Q000096:biosynthesis; D004896:Erythritol / Q000378:metabolism; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains
D001647:Bile Acids and Salts; D010936:Plant Extracts; D004896:Erythritol