Hyperproteic diet and pregnancy of rat.
We have studied the effects of a purified diet enriched with animal protein (casein 40%, lactalbumin 20%) on different stages of rat pregnancy. We observed that hyperproteic diet, especially when administered from the first day of pregnancy, induces morphological alterations of liver, adrenal cortex, heart and kidney. Moreover, haematic dosages, carried out on 15th day of pregnancy, have shown moderate but significant increase of glucose and triglycerides and significant decrease of circulating aldosterone and corticosterone as well. Finally an early administration of hyperproteic diet causes less numerous litters and high mortality rate at birth.
D000302:Adrenal Cortex / Q000473:pathology; D000305:Adrenal Cortex Hormones / Q000097:blood; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D004044:Dietary Proteins / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D011247:Pregnancy; D011270:Pregnancy, Animal; D051381:Rats; D011919:Rats, Inbred Strains; D014280:Triglycerides / Q000097:blood
D000305:Adrenal Cortex Hormones; D001786:Blood Glucose; D004044:Dietary Proteins; D014280:Triglycerides