The clinical course in primary angle-closure glaucoma: a reassessment.
Using ultrasonography, the authors made biometric measurements in 92 eyes of 47 patients with primary angle-closure glaucoma (ACG) and calculated the lens thickness/axial length factor (LAF) for each patient. Graphical and statistical analysis suggest the presence of three distinct clinical groups of patients with primary ACG. ACG shows a dynamic clinical picture; it starts in an eye which is initially uncompromised (group A) and progresses to one of two identifiable advanced stages (groups B and C). Accurate diagnosis by following LAF values in the earliest stage of the disease could prevent its development into the later stages.
D000328:Adult; D000368:Aged; D000375:Aging; D005260:Female; D005901:Glaucoma / Q000145:classification* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007908:Lens, Crystalline / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012044:Regression Analysis