Evidence for a role of adrenals in the capsaicin-sensitive "gastric defence mechanism" in rats.
Capsaicin desensitization increases the degree of indomethacin-induced gastric ulcers in sham-operated but not in adrenalectomized rats. These results suggest that adrenals play a role in the capsaicin-sensitive "gastric defence mechanism".
D000311:Adrenal Glands / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D002211:Capsaicin / Q000494:pharmacology*; D007213:Indomethacin / Q000633:toxicity; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000139:chemically induced* / Q000503:physiopathology
D002211:Capsaicin; D007213:Indomethacin