title: The effect of hemodialysis on lymphocyte subsets during dialysis.
abstract: To clarify the effect of hemodialysis on immune response of dialysis patients, peripheral lymphocyte subsets were measured using monoclonal antibodies, OKT3, OKT4, OKT8, OKIal and Leu7. The absolute numbers of OKT3+, OKT4+, OKT8+ and OKIal+ cells were significantly lower in dialysis patients than controls. During dialysis, the relative proportions of OKT3+ and OKT4+ cells increased, and the absolute numbers of OKIal+ and OKT8+ cells decreased, 30 minutes after initiation of dialysis. At the end of the dialysis, the absolute numbers of OKT3+ and OKT4+ cells increased. The absolute number of Leu7+ cells showed low values during dialysis. These changes of lymphocyte subsets during dialysis may have influence on the immune response of dialysis patients.
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007676:Kidney Failure, Chronic / Q000276:immunology / Q000628:therapy*; D008214:Lymphocytes / Q000145:classification*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
chemical_list: D000911:Antibodies, Monoclonal