The development of thyrotoxicosis (Graves' disease) during immunosuppression for autoimmune haemolytic anaemia.
A patient is described who developed thyrotoxicosis (Graves' disease) during immunosuppressive therapy for acquired autoimmune haemolytic anaemia. The fact that the two conditions may be associated should be recognised. Long-term immunosuppressive therapy does not prevent the development of immunoglobulins of IgG type postulated to be aetiologically involved in Graves' disease.
D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology / Q000628:therapy*; D001379:Azathioprine / Q000009:adverse effects; D005260:Female; D006111:Graves Disease / Q000209:etiology* / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D011239:Prednisolone / Q000009:adverse effects; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000276:immunology / Q000628:therapy*; D011877:Radionuclide Imaging; D013156:Splenectomy; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000000981:diagnostic imaging
D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D011239:Prednisolone; D001379:Azathioprine