[Effect of aminoglycosides on experimentally induced endolymphatic hydrops].
Gentamycin or kanamycin have no effect on endolymph formation in experimental induced endolymphatic hydrops. The increase of endolymphatic volume after obliteration of endolymphatic duct and sac is not influenced by aminoglycosides as well as the decrease of DC-potential and the increase of sodium-activity in endolymphatic hydrops. The way of action of intratympanal injected gentamycin seems to be in a partial chemical induced labyrinthectomy.
D000818:Animals; D004710:Endolymph / Q000187:drug effects; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D006168:Guinea Pigs; D007612:Kanamycin / Q000627:therapeutic use*; D008297:Male; D008575:Meniere Disease / Q000188:drug therapy*
D005839:Gentamicins; D007612:Kanamycin
Zur Wirkung von Aminoglykosiden auf den experimentell erzeugten endolymphatischen Hydrops.