[Disorders of the functional properties of thrombocytes causing thromboembolism in acute suppurative destructive diseases of the lungs and pleura].
An examination of 96 patients has established that the development of a pyo-destructive process in the lungs and pleura is accompanied by an increase of concentration of circulating thrombocytes as well as their adhesive-aggregating activity and degenerative-dystrophic alterations. These parameters were most pronounced in patients 1-3 days before their sudden death from thromboembolism of the pulmonary artery without a clinically detected source. Persantine, aspirin, pyrazolones and heparin in generally accepted therapeutic doses were shown not to possess evident anti-aggregative properties.
D000208:Acute Disease; D001792:Blood Platelets / Q000502:physiology*; D004653:Empyema / Q000097:blood / Q000150:complications*; D006801:Humans; D008169:Lung Abscess / Q000097:blood / Q000150:complications*; D010973:Platelet Adhesiveness; D010974:Platelet Aggregation; D011655:Pulmonary Embolism / Q000097:blood / Q000209:etiology*
Narusheniia funktsional'nykh svoĭstv trombotsitov, sposobstvuiushchie formirovaniiu tromboemboliĭ, pri ostrykh gnoĭno-destruktivnykh zabolevaniiakh legkikh i plevry.