title: Successful treatment of meningeal myeloma with combination of radiation therapy, chemotherapy, and intrathecal therapy.
abstract: Meningeal involvement is a rare complication of multiple myeloma. None of the previously described patients presenting this syndrome had responded to treatment. We describe a 64-year-old man with meningeal myelomatosis. A favorable response to treatment was produced by radiation therapy administered to the head and by intrathecal and systemic chemotherapy including high-dose corticosteroids.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D001859:Bone Neoplasms / Q000556:secondary; D003131:Combined Modality Therapy; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D008577:Meningeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones