[Autoradiographic determination of 3H-thymidine incorporation in ovarian tumor cells and the value of this in vitro study for tumor chemotherapy].
According to our experiences the incorporation of 3H-thymidine in ovarian cancer cells determined by autoradiography represents a method of additional tumour characterization. The in-vitro-tests allow roughly hints about the efficiency of an intended therapy in 49 patients suffering from ovarian cancer. High risk patients may be excluded from a chemotherapy, if the incorporation of thymidine is low. For this decision we also evaluate the results of oncobiogram and clinical parameters. The 3H-thymidine incorporation enables to elect an individual kind of therapy for any patient with regard to success and duration of treatment.
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004273:DNA, Neoplasm / Q000096:biosynthesis; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000235:genetics
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm
Autoradiographische 3H-Thymidineinbaubestimmungen in Ovarialtumorzellen und die Aussagefähigkeit dieser In-vitro-Untersuchungen für Belange der Tumorchemotherapie.