The influence of partial hepatectomy and carbon tetrachloride on rat stomachs.
Carbon tetrachloride (CCl4) injection, but not partial hepatectomy, significantly increased gastric acid secretion and ulceration in rats. Both procedures did not influence serum IgG levels, but markedly elevated serum alanine and aspartate aminotransferase activities. It appears that short-term liver injury produced by CCl4, but not hepatectomy, adversely affects rat stomachs.
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D002251:Carbon Tetrachloride / Q000633:toxicity*; D005744:Gastric Acid / Q000378:metabolism; D006498:Hepatectomy; D008099:Liver / Q000502:physiology*; D008297:Male; D010437:Peptic Ulcer / Q000209:etiology; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000187:drug effects / Q000293:injuries*
D002251:Carbon Tetrachloride; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase