Inhibition of pulmonary surfactant by plasma from normal adults and from patients having cardiopulmonary bypass.
Plasma from normal adults and from children and adults having cardiopulmonary bypass inhibited the ability of pulmonary surfactant to reach low surface tension in proportion to the amount of protein added. No increase in the extent of inhibition of surfactant action per milligram of protein was seen in plasma taken before or after bypass in adults or children.
D000328:Adult; D001798:Blood Proteins / Q000502:physiology; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D002648:Child; D006801:Humans; D010743:Phospholipids / Q000502:physiology; D010949:Plasma / Q000502:physiology*; D011663:Pulmonary Surfactants / Q000037:antagonists & inhibitors* / Q000502:physiology; D012128:Respiratory Distress Syndrome / Q000209:etiology; D013997:Time Factors
D001798:Blood Proteins; D010743:Phospholipids; D011663:Pulmonary Surfactants