Distribution of fibroblast growth factor in the central and peripheral nervous systems of various mammals.
Fibroblast growth factor (FGF) is a potent, mesodermal cell mitogen which has been identified throughout the central nervous system of various mammals and shown to display no regional concentration differences within the brain. An FGF-like mitogen of similar specific activity is also identified in the peripheral nervous system. Although not myelin-derived, these factors may arise from some component, of neuronal or glial origin, common to the central and peripheral nervous systems.
D000818:Animals; D001923:Brain Chemistry; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D005346:Fibroblast Growth Factors / Q000494:pharmacology / Q000502:physiology*; D008322:Mammals / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D010525:Peripheral Nerves / Q000032:analysis / Q000502:physiology*; D013045:Species Specificity; D013116:Spinal Cord / Q000032:analysis / Q000502:physiology*; D014020:Tissue Extracts
D014020:Tissue Extracts; D005346:Fibroblast Growth Factors