title: An automated microcomputer-based system for determining canine paw pressure quantitatively in the dog synovitis model.
abstract: The automated system for measuring canine paw pressure is a very useful tool for the evaluation of nonsteroid antiinflammatory drugs such as indomethacin and ibuprofen in the dog synovitis model. The apparatus has been designed to give the operator control over the dog's posture while measuring hind-paw pressure. The stability of the measuring platform permits reproducible measurement of paw pressures. The software package performs direct data recording and data reduction and eliminates tedious manual calculations. Subsequently, the software produces a printout summarizing the experimental results in tabular and graphic form.
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D005528:Foot / Q000502:physiology / Q000503:physiopathology*; D007052:Ibuprofen / Q000494:pharmacology; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D008838:Microcomputers; D011312:Pressure; D012984:Software; D013585:Synovitis / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D007052:Ibuprofen; D007213:Indomethacin