[Clinical value of assays of parathyroid hormone and 25-hydroxyvitamin D in internal medicine].
Over a 3 years period, PTH, 25 OHD, calcium and phosphate levels were measured in all patients admitted to a department of Internal Medicine with abnormal phospho-calcic metabolism or bone disease. The diagnostic value of iPTH was analysed, especially in cases of hyper- and hypocalcaemia. In hypercalcaemia, the iPTH did not differentiate between the two main differential diagnoses: hyperparathyroidism and cancer. In patients with a negative calcium balance, the iPTH level is often raised and many help towards diagnosis. However, it should first of all orientate the clinician towards the detection of renal failure which is a common cause of this condition.
D058186:Acute Kidney Injury / Q000175:diagnosis; D002112:Calcifediol / Q000097:blood*; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006996:Hypocalcemia / Q000209:etiology; D009369:Neoplasms / Q000175:diagnosis; D010279:Parathyroid Diseases / Q000175:diagnosis; D010281:Parathyroid Hormone / Q000097:blood*; D011863:Radioimmunoassay
D010281:Parathyroid Hormone; D002112:Calcifediol
Intérêt clinique des dosages de parathormone (PTH) et 25 hydroxyvitamine D (25 OHD) en médecine interne.