Pathology of degenerative osteoarthrosis of the thoracic vertebrae in rats.
Degenerative osteoarthrosis was observed in the thoracic vertebrae in specific pathogen-free Sprague-Dawley rats at the ages of eight and 19 weeks. Histological changes seen in the lesions were degenerated matrix intermixed with collagen fibers, erosion or ulceration, and formation of cysts in the articular cartilage, and degeneration and necrosis in the subchondral bone.
D000818:Animals; D002356:Cartilage / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000473:pathology*; D013122:Spinal Diseases / Q000473:pathology / Q000662:veterinary*; D013904:Thoracic Vertebrae / Q000473:pathology*