title: Microassay for estimation of galactose and galactose-1-phosphate in dried blood specimens.
abstract: A fluorometric assay for blood galactose and galactose-1-phosphate has been modified and improved to shorten the analysis time and to increase sensitivity above other published methods. The method may be useful as a quantitative screening or routine clinical test to detect infants suspected of having a defect of galactose metabolism. It can also be used to monitor blood galactose or galactose-1-phosphate levels in children with galactosemia who are on a lactose-free diet.
mesh_terms: D000469:Alkaline Phosphatase / Q000494:pharmacology; D001801:Blood Stains; D005470:Fluorometry; D005690:Galactose / Q000032:analysis*; D005691:Galactose Dehydrogenases / Q000494:pharmacology; D005693:Galactosemias / Q000175:diagnosis; D005695:Galactosephosphates / Q000097:blood*; D006600:Hexosephosphates / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D008832:Microchemistry / Q000379:methods
chemical_list: D005695:Galactosephosphates; D006600:Hexosephosphates; C029973:galactose-1-phosphate; D005691:Galactose Dehydrogenases; C047959:galactose dehydrogenase; D000469:Alkaline Phosphatase; D005690:Galactose