title: [Effect of chronic administration of ethanol on the blood-brain barrier permeability of 14C-tyrosine and horseradish peroxidase in rats].
abstract: Chronic 10-days oral ethanol administration in doses 8-11 g/kg per day has been shown to increase blood-brain barrier penetration for peripherally administered 14C-tyrosine in Wistar heavy- and light-drinker rats. No changes in BBB permeability for horseradish peroxidase has been found. Chronic effect of ethanol on BBB systems of specific and unspecific transport in rats heavy- and light-drinkers is discussed.
mesh_terms: D000437:Alcoholism / Q000378:metabolism*; D000818:Animals; D001812:Blood-Brain Barrier / Q000187:drug effects*; D006735:Horseradish Peroxidase; D008297:Male; D010539:Permeability; D051381:Rats; D011919:Rats, Inbred Strains; D014443:Tyrosine
chemical_list: D014443:Tyrosine; D006735:Horseradish Peroxidase
vernacular_title: Vliianie khronicheskogo vvedeniia étanola na pronitsaemost' gematoéntsefalicheskogo bar'era dlia 14C-tirozina i peroksidazy khrena u krys.