Isolation and characterization of A41030, a complex of novel glycopeptide antibiotics. Application of the Michel-Miller high performance low pressure liquid chromatography system.
A new antibiotic complex, designated A41030, has been isolated from the fermentation broth of Streptomyces virginiae. Factors A, B, C, D, E, F and G were separated by an efficient preparative high performance low pressure liquid chromatography system. The apparatus offers economic reversed phase separations on glass columns. The A41030 factors are members of the general class of glycopeptide antibiotics and are active in vitro and in vivo vs. Gram-positive bacteria.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D006020:Glycopeptides / Q000302:isolation & purification; D013302:Streptomyces / Q000378:metabolism
D000900:Anti-Bacterial Agents; D006020:Glycopeptides; C044842:A 41030