[Examples for possible tumor induction by immunosuppressive and cytostatic drugs (case studies)].
The problems of immunosuppressive and cancer therapy are discussed based on five case reports. In each case neoplasms were observed, which appear to have been caused by the previous treatment. A tumor is particularly tragic when it follows immunosuppression for chronic inflammatory disease (eg. uveitis, rheumatoid arthritis).
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D001379:Azathioprine / Q000009:adverse effects; D003131:Combined Modality Therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000139:chemically induced*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000139:chemically induced; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced
D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents; D001379:Azathioprine
Beispiele für eine mögliche Tumorinduktion durch immunsuppressive und zytostatische Therapeutika (Kasuistische Betrachtungen).