Cholinergic dermographism.
We report a patient with cholinergic urticaria in whom stroking the skin produced a band of erythema studded with the small weals characteristics of cholinergic urticaria. This response was suppressed by pre-treatment with topical scopolamine. Light and electron microscopy of the weal showed mast cell degranulation and a moderate mononuclear cell infiltrate.
D000109:Acetylcholine / Q000037:antagonists & inhibitors / Q000502:physiology*; D000328:Adult; D002452:Cell Count; D005260:Female; D006801:Humans; D008407:Mast Cells / Q000473:pathology; D012601:Scopolamine / Q000494:pharmacology; D012867:Skin / Q000187:drug effects / Q000473:pathology*; D014581:Urticaria / Q000209:etiology / Q000473:pathology*
D012601:Scopolamine; D000109:Acetylcholine