[Comparative evaluation of the clinical course and dynamics of the morphological changes in chronic glomerulonephritis].
The results of a simultaneous study of a clinical and morphological course of chronic glomerulonephritis (CGN) in 30 patients after repeated morphological investigation of the renal tissue showed that a prevailing tendency in this disease was the progression of morphological changes which could be noted in a stable clinical picture and even in clinical improvement. The detection of tubulointerstitial changes in the first nephrobiopsy was an unfavorable prognostic factor. Of the greatest importance for indirect assessment of a morphological course of CGN were changes in creatinine clearance, effective renal plasma flow and arterial pressure. A morphological course of different variants of CGN and the effect of pathogenetic therapy on it were analyzed.
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged
Sravnitel'naia otsenka klinicheskogo techeniia i dinamiki morfologicheskikh izmeneniĭ pri khronicheskom glomerulonefrite.