title: Laterality associated with sexual dimorphism in the volume of the mouse hypogastric ganglion.
abstract: The volume of the hypogastric ganglion was investigated in male, female, and prenatally androgen-exposed female newborn mice. Two milligram testosterone propionate was injected into pregnant ICR mice from days 14 to 16 of gestation. The volume of the ganglia on both sides in intact male neonates was significantly larger than that in female neonates. The volume of ganglia in testosterone-exposed females was significantly larger than those in intact females, but did not attain the male volume. In intact males, the ganglion on the left side was significantly larger than on the right. This left-right difference in the volume of the ganglia was not recognized in the intact or TP-exposed females. These results suggest that sex difference and lateralization of the volume of the hypogastric ganglion were highly dependent on the prenatal sex hormone environment.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D005260:Female; D007839:Functional Laterality; D005725:Ganglia, Autonomic / Q000187:drug effects / Q000502:physiology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D012727:Sex Characteristics; D013270:Stomach / Q000294:innervation; D013739:Testosterone / Q000494:pharmacology
chemical_list: D013739:Testosterone