Auditory evoked potentials during isoflurane anaesthesia.
Brainstem auditory evoked potentials (BAEP) were determined in 12 volunteers. The effect of isoflurane anaesthesia on BAEP was determined in six patients. Body temperature and end-tidal CO2% were controlled. Increasing end-tidal isoflurane concentration from 0.6-2.4% increased BAEP wave I, III and V latencies. The amplitude of wave V decreased with increasing isoflurane concentration. Thus a dose-related change was demonstrated between end-tidal concentration of isoflurane and BAEP latencies.
D000328:Adult; D000771:Anesthesia, Intravenous; D001306:Auditory Pathways / Q000187:drug effects; D001921:Brain / Q000187:drug effects*; D001933:Brain Stem / Q000187:drug effects; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D009431:Neural Conduction / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects
D007530:Isoflurane