title: [Comparative study of the antineoplastic and immunoadjuvant activity of acrylic acid (co)polymers].
abstract: The paper deals with the carcinostatic and immunomodifying action of synthetic polyelectrolytes containing acid and basic groups as well as of polyampholytes and nonionogenic polymers. Polyacrylic acid was found to possess the highest antitumour and adjuvant activity. The antitumour effect of polyacrylic acid increases with its molecular mass. Introduction of other polymers into a polymer chain of acrylic acid results in a decrease in its antitumour and immunoadjuvant action.
mesh_terms: D000180:Acrylic Resins / Q000276:immunology / Q000627:therapeutic use; D000276:Adjuvants, Immunologic / Q000276:immunology; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy; D051379:Mice
chemical_list: D000180:Acrylic Resins; D000276:Adjuvants, Immunologic; D000970:Antineoplastic Agents
vernacular_title: Sravnitel'noe izuchenie protivoopukholevoĭ i immunoad"iuvantnoĭ aktivnosti (so)polimerov akrilovoĭ kisloty.