Characterization of the Yucatan miniature pig skin and small intestine for pharmaceutical applications.
Yucatan miniature pig skin and gastrointestinal tract have been characterized as potential models for human organ systems in in vitro and in vivo pharmaceutical experiments. Histology of pig skin and the flux of one classical drug, caffeine, are described. The Yucatan small intestine was examined morphologically. Both Yucatan skin and GI tract were found to have similarities to man.
D000818:Animals; D002110:Caffeine / Q000378:metabolism; D007421:Intestine, Small / Q000033:anatomy & histology*; D008297:Male; D010539:Permeability; D012867:Skin / Q000033:anatomy & histology* / Q000378:metabolism; D013552:Swine; D013556:Swine, Miniature / Q000033:anatomy & histology*
D002110:Caffeine