[Synthesis of xylose-containing glycopeptides that contain the amino acid sequence 4 bis 7 des NH2-terminus of the protein core structure of cattle skin proteodermatan sulfates].
The synthesis is described of alpha-beta-D-xylopyranosyl-L-serylglycyl-L-isoleucyl-glycine (7), a glycopeptide containing the amino acid sequence of the protein core-structure of beef-skin proteodermatan sulfate; coupling of N-protected O-XylpSer with protected GlyIleuGly followed by deprotection afforded 7.
D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D002807:Chondroitin / Q000031:analogs & derivatives*; D003871:Dermatan Sulfate / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D006020:Glycopeptides / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D011509:Proteoglycans / Q000138:chemical synthesis*; D012867:Skin / Q000032:analysis*; D014994:Xylose
D006020:Glycopeptides; D007202:Indicators and Reagents; D011509:Proteoglycans; C028774:proteodermatan sulfate; C050520:xylopyranosyl-seryl-glycyl-isoleucyl-glycine; D003871:Dermatan Sulfate; D002807:Chondroitin; D014994:Xylose
Synthese eines Xylose-haltigen Glycopeptides, das die Aminosäure-Sequenz 4 bis 7 des NH2-terminus der Protein-Core-Struktur des Rinderhaut-Proteodermatan-Sulfats enthalt.