Retinal pigment epithelial hyperplasia assuming tumor-like proportions. Report of two cases.
Two patients who had highly elevated pigmented masses associated with a chorioretinal scar were observed clinically for several years. The scar was due to presumed histoplasmosis in one patient and toxoplasmosis in the other. Histopathological examination disclosed choroidal and subretinal masses consisting of hyperplastic retinal pigment epithelium. The difficulty in making the diagnosis of RPE hyperplasia in such instances is discussed.
D002829:Choroid; D002921:Cicatrix / Q000150:complications; D005260:Female; D006660:Histoplasmosis / Q000150:complications; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000150:complications; D014126:Toxoplasmosis, Ocular / Q000150:complications; D014603:Uveal Diseases / Q000150:complications