[Unstable stenocardia: the results of the intracoronary administration of fibrinolytic agents].
Intracoronary thrombolytic infusions were used in 10 patients with unstable angina and high risk of myocardial infarction (MI). Streptokinase (500,000 units per hour) was used in 9 patients, and urokinase, in one. Vascular recanalization was achieved in 4 cases where angiography showed coronary arterial occlusion by a thrombus. Myocardial infarction developed in 8 patients (large-focal in 6 and small-focal in 2) within 1 to 16 days after the thrombolytic infusion. Therefore, short-term local thrombolytic infusion fails to prevent myocardial infarction in patients with unstable angina.
D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy*; D000789:Angina, Unstable / Q000150:complications / Q000188:drug therapy*; D003331:Coronary Vessels; D004562:Electrocardiography; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology / Q000517:prevention & control; D012306:Risk; D013997:Time Factors
D005343:Fibrinolytic Agents
Nestabil'naia stenokardiia: rezul'taty vnutrikoronarnogo vvedeniia fibrinoliticheskikh sredstv.