title: [Structural properties of leukemic and normal lymphoid cells].
abstract: DNA synthesis intensity and spectral and fluorescent properties of leucemic, PHA-induced and intact normal mouse spleen cells and of nuclei isolated from these cells were investigated. The cell electrophoretic mobility and DNA-protein interaction in the nuclei were studied. Similarity in cell and nuclei fluorescence, fluorescence of the probe ANS conjugated with the cells, the electrophoretic mobility and tightness of DNA--protein interaction for leucemic and PHA--induced cells and also the similarity of the tightness of DNA--protein interaction for leucemic and normal intact cells were found inspite of the differences in DNA synthesis intensity and cell functional peculiarities.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D005456:Fluorescent Dyes; D007942:Leukemia, Experimental / Q000378:metabolism*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000378:metabolism*; D051379:Mice; D008810:Mice, Inbred C57BL; D013056:Spectrophotometry, Ultraviolet; D013154:Spleen / Q000166:cytology / Q000378:metabolism
chemical_list: D004273:DNA, Neoplasm; D005456:Fluorescent Dyes; D004247:DNA
vernacular_title: Strukturnye svoĭstva leĭkoznykh i normal'nykh limfoidnykh kletok.