A possible effect on the Shwartzman reaction in the rabbit caused by fentanyl-fluanisone tranquillization.
Shwartzman's reaction was elicited in four Chinchilla rabbits. Two of the animals were tranquillized with fentanyl-fluanisone (Hypnorm: Janssen Pharmaceuticals). There was a reduced response in the tranquillized rabbits while the untranquillized animals developed the typical dose-responsive skin reaction. Fentanyl-fluanisone tranquillization may interfere with the development of the Shwartzman reaction in Chinchilla rabbits.
D000818:Animals; D002090:Butyrophenones / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D005283:Fentanyl / Q000494:pharmacology*; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D011817:Rabbits; D012790:Shwartzman Phenomenon; D014149:Tranquilizing Agents / Q000494:pharmacology*
D002090:Butyrophenones; D004338:Drug Combinations; D006993:Hypnotics and Sedatives; D014149:Tranquilizing Agents; C001432:Hypnorm; D005283:Fentanyl