Factor V inhibitor associated with immune complex formation.
A 72-year-old man was noted, shortly after surgery, to have a bleeding diathesis secondary to the development of a high-titer anti-factor V inhibitor. We documented the presence of factor V:anti-factor V IgG immune complexes and their disappearance following a short course of steroid therapy.
D000005:Abdomen / Q000601:surgery; D000368:Aged; D000936:Antigen-Antibody Complex / Q000276:immunology*; D001778:Blood Coagulation Disorders / Q000188:drug therapy / Q000503:physiopathology*; D005165:Factor V / Q000276:immunology*; D006801:Humans; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G / Q000276:immunology; D008297:Male; D010314:Partial Thromboplastin Time; D011184:Postoperative Period; D011241:Prednisone / Q000627:therapeutic use; D011517:Prothrombin Time
D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D005165:Factor V; D011241:Prednisone