title: Prevention of coagulopathy after placement of peritoneovenous shunt with replacement of ascitic fluid by normal saline solution.
abstract: Consumptive coagulopathy may complicate the early postoperative course of peritoneovenous shunting and be responsible for diffuse bleeding or even death. Since this complications has been related to procoagulant substances in ascitic fluid getting access to the systemic circulation, it was demonstrated that the replacement of the ascitic fluid by normal saline solution during shunt insertion decreases the prevalence and severity of postoperative coagulopathy.
mesh_terms: D000328:Adult; D000368:Aged; D001202:Ascitic Fluid; D001780:Blood Coagulation Tests; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D005165:Factor V / Q000032:analysis; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008875:Middle Aged; D010536:Peritoneovenous Shunt / Q000009:adverse effects / Q000379:methods*; D010976:Platelet Count; D011184:Postoperative Period; D011517:Prothrombin Time; D012965:Sodium Chloride
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C011468:fibrinmonomer; D012965:Sodium Chloride; D005165:Factor V; D005340:Fibrinogen