title: Antidepressants: their uses in nonpsychiatric disorders of aging.
abstract: Antidepressants are recommended by some clinicians as therapy for irritable colon even when there is no evidence of clinical depression, since this syndrome may represent a type of chronic masked depression. Antidepressants may be a good alternative in elderly patients with peptic ulcer disease, particularly in those with concurrent depression. Advantages include once-a-day administration, lower cost, and ease of serum monitoring.
mesh_terms: D000342:Affective Symptoms / Q000188:drug therapy; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D003109:Colonic Diseases, Functional / Q000188:drug therapy; D003863:Depression / Q000188:drug therapy; D004316:Doxepin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D009290:Narcolepsy / Q000188:drug therapy; D009627:Nomifensine / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy; D010437:Peptic Ulcer / Q000188:drug therapy; D011530:Protriptyline / Q000627:therapeutic use; D012891:Sleep Apnea Syndromes / Q000188:drug therapy; D013577:Syndrome; D014299:Trimipramine / Q000627:therapeutic use; D014549:Urinary Incontinence / Q000188:drug therapy
chemical_list: D000928:Antidepressive Agents; D004316:Doxepin; D009627:Nomifensine; D011530:Protriptyline; D014299:Trimipramine; D007099:Imipramine