title: Intrathecal baclofen for severe spasticity.
abstract: The intrathecal administration of baclofen by way of an implanted subcutaneous drug delivery system is described in a patient with a severe spastic paraparesis due to multiple sclerosis. Intrathecally-administered baclofen is proposed as another therapeutic dimension and adjunct to physical therapy in the management of patients with severe spasticity that is unresponsive to antispasticity agents administered by mouth.
mesh_terms: D000328:Adult; D001418:Baclofen / Q000008:administration & dosage* / Q000627:therapeutic use; D002408:Catheters, Indwelling; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D009103:Multiple Sclerosis / Q000150:complications*; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology
chemical_list: D001418:Baclofen