[Alpha-tocopherol concentration of the blood plasma and erythrocytes in patients with symptomatic obesity due to hypothalamo-hypophyseal-adrenal diseases].
Healthy persons, patients with noncomplicated alimentary and hypothalamic obesity and those with pubertal dyspituitarism or Icenko-Cushing's disease were studied for serum and erythrocytic levels of alpha-tocopherol. In normal subjects the levels of alpha-tocopherol in the blood serum are increasing with age. In patients with alimentary obesity and pubertal dyspituitarism the percentage of alpha-tocopherol elevation correlates with that of serum lipids and alpha-tocopherol erythrocytic levels are not higher than in normal subjects. In patients with hypothalamic obesity and in particular with Icenko-Cushing's disease relative incompetence of alpha-tocopherol in the blood serum was accompanied by decreased levels of alpha-tocopherol in red blood cells (absolute deficit of alpha-tocopherol in tissues).
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D003480:Cushing Syndrome / Q000097:blood / Q000150:complications*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D007027:Hypothalamic Diseases / Q000097:blood / Q000150:complications*; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000209:etiology; D010900:Pituitary Diseases / Q000097:blood / Q000150:complications*; D011627:Puberty; D012008:Recurrence; D014810:Vitamin E / Q000097:blood*
D008055:Lipids; D014810:Vitamin E
Kontsentratsiia al'fa-tokoferola v plazme krovi i v éritrotsitakh bol'nykh simptomaticheskim ozhireniem, obuslovlennom gipotalamo-gipofizarno-nadpochechnikovymi zabolevaniiami.