Activation of the auditory cortex by cochlear stimulation in a deaf patient.
We have recorded cerebral electric and magnetic responses to electric stimulation of the auditory nerve in a deaf patient with multichannel cochlear prosthesis. The electric response peaked with a vertex-negative deflection at 65 ms. Clear magnetic responses, coinciding with the vertex potential, were obtained only over the hemisphere ipsilateral to the stimulation; the field pattern indicated activation of the auditory cortex within the Sylvian fissure. The results suggest modification of the central auditory pathways in this patient deaf from early childhood.
D001303:Auditory Cortex / Q000503:physiopathology*; D001306:Auditory Pathways / Q000503:physiopathology; D003054:Cochlear Implants; D003638:Deafness / Q000503:physiopathology* / Q000534:rehabilitation; D005072:Evoked Potentials, Auditory; D005260:Female; D006801:Humans; D008875:Middle Aged; D000159:Vestibulocochlear Nerve / Q000503:physiopathology*