A case of fatal sodium azide ingestion.
A fatal case of sodium azide poisoning in which exchange blood transfusions, charcoal hemoperfusion, hemodialysis and potent vasopressor agents failed to prevent the development of circulatory collapse associated with a wide complex cardiac rhythm is presented. The cellular toxin sodium azide resulted in the development of an altered mental status, profound metabolic acidosis, cardiac arrhythmia (atrial fibrillation and terminal wide complex arrhythmias), a relative decrease in cardiac output, hypotension and non-cardiogenic pulmonary edema. Further animal studies are needed to gain new approaches for the treatment of this rare cause of human poisoning.
D000138:Acidosis / Q000139:chemically induced; D000328:Adult; D001386:Azides / Q000506:poisoning*; D002319:Cardiovascular System / Q000187:drug effects; D003486:Cyanides / Q000633:toxicity; D005260:Female; D006801:Humans; D008297:Male; D011654:Pulmonary Edema / Q000139:chemically induced; D019810:Sodium Azide
D001386:Azides; D003486:Cyanides; D019810:Sodium Azide