Profound behavioral toxicity due to tricyclic antidepressants.
The incidence of tricyclic antidepressant-induced behavioral toxicity appears to be fairly high in elderly patients but has rarely been reported in the young. We present a case of significant behavioral side effects in a young woman secondary to elevated plasma levels of imipramine and desipramine, masquerading as an agitated psychotic depression.
D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D003863:Depression / Q000139:chemically induced* / Q000188:drug therapy / Q000523:psychology; D003891:Desipramine / Q000009:adverse effects* / Q000097:blood; D005260:Female; D006760:Hospitalization; D006801:Humans; D007099:Imipramine / Q000009:adverse effects* / Q000097:blood; D011605:Psychoses, Substance-Induced / Q000209:etiology*
D007099:Imipramine; D003891:Desipramine