title: The use of a rapid in situ technique for third-trimester diagnosis of trisomy 18.
abstract: A rapid in situ coverslip technique was used to diagnose trisomy 18 within 1 week of amniocentesis in the third trimester. Two cases are presented. The clinical significance and advantages over umbilical vein aspiration are discussed.
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis; D000328:Adult; D000649:Amniocentesis; D000653:Amniotic Fluid / Q000166:cytology; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011296:Prenatal Diagnosis; D014314:Trisomy