A paracentric inversion of 7q illustrating a possible interchromosomal effect.
A family is described in which the proband has a rearranged X chromosome involving monosomy Xp and trisomy Xq, while the mother has a paracentric inversion of chromosome 7. It is suggested that the phenomenon of interchromosomal effect may link these observations. A brief review of the published and computer catalogued data on paracentric inversion in man is included.
D007446:Chromosome Inversion; D002906:Chromosomes, Human, 6-12 and X; D004261:DNA Replication; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008540:Meiosis; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D014960:X Chromosome