title: Passive hemagglutination test for antibody to hepatitis B core antigen.
abstract: Available tests for antibody to hepatitis B core antigen (anti-HBc) are complicated. A passive hemagglutination assay for anti-HBc was developed by sensitizing sheep erythrocytes with hepatitis B core antigen synthesized by a recombinant DNA technique. It was compared with a commercial passive hemagglutination assay and an enzyme-linked immunosorbent assay for anti-HBc and showed good agreement with both. It is rapid, simple, and sensitive.
mesh_terms: D004274:DNA, Recombinant; D004797:Enzyme-Linked Immunosorbent Assay; D006386:Hemagglutination Tests; D006510:Hepatitis B Antibodies / Q000032:analysis*; D006512:Hepatitis B Core Antigens / Q000276:immunology*; D006801:Humans
chemical_list: D004274:DNA, Recombinant; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens