title: [Diclofenac-Na--an alternative treatment possibility in therapy-resistant calcium oxalate urolithiasis?].
abstract: In a prospective study, the influence of sole Diclofenac-Na therapy (3 X 25 mg Rewodina, Voltaren) on the calculus recurrence rate of eight frequently relapsing and therapy resistant calcium-oxalate stone patients is analysed. During a period of one year's treatment, the recurrence rate could be reduced by 73.2%, from 123 to 33 calculi. Serious side effects, changes in blood serological parameters and various urine components were not observed. The course of passages of calculi was improved by reduced pain and rapid passage. The paper summarizes all results of calcium-oxalate stone treatments with nonsteroidal antiphlogistics known so far. In the opinion of the authors, the present successful Diclofenac-Na treatment offers a novel possibility of influencing therapy resistant stone-formers over long periods.
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D002129:Calcium Oxalate / Q000652:urine*; D004008:Diclofenac / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000188:drug therapy* / Q000652:urine; D008297:Male; D008875:Middle Aged; D012008:Recurrence
chemical_list: D004008:Diclofenac; D002129:Calcium Oxalate
vernacular_title: Diclofenac-Na--eine alternative Behandlungsmöglichkeit beim therapieresistenten Kalzium-Oxalat-Harnsteinleiden?