title: [Microcirculatory and hemostatic disorders in calculous pyelonephritis patients].
abstract: The state of microcirculation and the system of hemostasis were studied over time in 52 patients with chronic calculous pyelonephritis. Investigations were performed before operation, after 2-4 days, 5-7 days and on discharge. The patients were divided into 2 groups: with chronic pyelonephritis in the phase of active inflammation and with chronic pyelonephritis in the phase of remission. Marked disorders in the system of hemostasis characterized by hyperfibrinogenemia, thrombinemia, a decrease in the heparincofactor plasma activity, activation of platelet hemostasis, a decrease in CPa-dependent fibrinolysis were noted in the patients with calculous pyelonephritis in the phase of active inflammation. These shifts were combined with disorders in the microcirculatory system: intermittent blood flow and disseminated erythrocyte aggregation, a prolonged period of nuclide half-life in the intracutaneous depot. In the patients with calculous pyelonephritis in the remission phase shifts in the system of hemostasis were less noticeable, microcirculatory disorders were undetectable.
mesh_terms: D000328:Adult; D001778:Blood Coagulation Disorders / Q000097:blood*; D002908:Chronic Disease; D003228:Conjunctiva / Q000098:blood supply*; D005260:Female; D005342:Fibrinolysis; D006487:Hemostasis; D006801:Humans; D007669:Kidney Calculi / Q000097:blood / Q000150:complications*; D008297:Male; D008833:Microcirculation / Q000503:physiopathology; D008875:Middle Aged; D011184:Postoperative Period; D011704:Pyelonephritis / Q000097:blood / Q000150:complications*
vernacular_title: Narusheniia mikrotsirkuliatsii i gemostaza u bol'nykh kal'kuleznym pielonefritom.