[Lipid peroxidation by rat brain synaptosomes in sleep disorders].
Paradoxical sleep deprivation for 24 hrs reduced lipid peroxidation in synaptosomes from the rat brain cortex. Production of conjugated dienes was shown to decrease by 30% and fluorescent products--by 18%, the level of thiobarbituric acid reactive products being unchanged. The sleep disturbance resulted in a 25% activation of superoxide dismutase.
D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism*; D008054:Lipid Peroxides / Q000096:biosynthesis*; D008297:Male; D008315:Malondialdehyde / Q000032:analysis; D008563:Membrane Lipids / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012892:Sleep Deprivation / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology*; D013482:Superoxide Dismutase / Q000378:metabolism; D013570:Synaptic Membranes / Q000378:metabolism; D013574:Synaptosomes / Q000378:metabolism
D008054:Lipid Peroxides; D008563:Membrane Lipids; D008315:Malondialdehyde; D013482:Superoxide Dismutase
Perekisnoe okislenie lipidov sinaptosom golovnogo mozgakrys pri narusheniisna.