[Differential condensation of human chromosomes 9 and Y].
Some differences were observed in the mitotic condensation of regions composing human chromosomes 9 and Y: regions 9p, 9h and Y nf are characterized by an intense condensation by the end of the spiralization interval studied (the length of the repair chromosome 3 varying from 5.4 to 2.9 mkm). At the same time, the condensation of regions 9q-h (region 9q without heterochromatic block) is slowing in the initial spiralization interval (the length of chromosome 3 varying from 16.6 to 5.5 mkm). The Yf-block of Y-chromosome is condensing faster than nf-region. The condensation parameters of Q-heterochromatic blocks are most variable while the euchromatic regions are most stable. The dynamics of 9h and of f-block condensation are independent within one karyotype. Based on the data obtained we doubt the correctness of studies on linear dimensions of the constitutive heterochromatin blocks for the evaluation of its quantity in the karyotype. A possible association of differential mitotic condensation with the chromosome segregation disturbances is discussed.
D002871:Chromosome Banding; D002899:Chromosomes, Human, Pair 9 / Q000648:ultrastructure*; D006570:Heterochromatin / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008938:Mitosis; D012044:Regression Analysis; D014998:Y Chromosome / Q000648:ultrastructure*
D006570:Heterochromatin
Differentsial'naia kondensatsiia khromosom 9 i Y cheloveka.