title: [Effect of the Japanese cucumaria on phospholipid metabolism in the liver of mice with solid Ehrlich carcinoma].
abstract: Japan cucumaria possesses an inhibitory action on the solid Ehrlich adenocarcinoma. The optimum dose, 15000 mg/kg, is established which provides a 46.49% of the growth inhibiting. The delay of the malignant process development is followed by normalization on phospholipid metabolism in the liver of tumour-bearing mice: the contents of phosphatidylcholine reached the normal level, the contents of sphingomyelin decreased, a portion of lysophosphatidylcholine and lysophosphatidylethanolamine was considerably reduced. The results obtained show that certain doses of cucumaria improve metabolic processes in the liver.
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy* / Q000378:metabolism; D004447:Echinodermata; D008099:Liver / Q000378:metabolism*; D051379:Mice; D010743:Phospholipids / Q000378:metabolism*; D012616:Sea Cucumbers
chemical_list: D000970:Antineoplastic Agents; D010743:Phospholipids
vernacular_title: Vliianie kukumarii iaponskoĭ na obmen fosfolipidov v pecheni myshi s solidnym rakom Erlikha.