title: Etiologic and serologic investigations of the 1980 epidemic of dengue fever on Hainan Island, China.
abstract: Virologic and seroepidemiologic studies were carried out during an epidemic of dengue fever on Hainan Island in 1980. Dengue 3 virus was isolated from 46 of 77 acute phase sera and from 1 of 10 pools of adult Aedes aegypti. Dengue 1 virus virus was isolated from a single acute phase serum. Seroepidemiologic investigations showed that 74% of healthy individuals in the epidemic area had antibody to dengue virus compared to 54% in an area where epidemic dengue had occurred in 1978, and less than or equal to 8% in nonepidemic areas. There were no significant differences in antibody prevalence for different sex and age groups.
mesh_terms: D000330:Aedes / Q000382:microbiology; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002681:China; D003715:Dengue / Q000453:epidemiology* / Q000382:microbiology; D003716:Dengue Virus / Q000276:immunology* / Q000302:isolation & purification; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D000914:Antibodies, Viral