A novel antagonist of serotonergic receptors, hymenidin, isolated from the Okinawan marine sponge Hymeniacidon sp.
A novel bromine-containing pyrrole compound, hymenidin, has been isolated from the Okinawan marine sponge Hymeniacidon sp. as a potent antagonist of serotonergic receptors and its structure elucidated using spectral data.
D000818:Animals; D001011:Aorta / Q000502:physiology; D001681:Biological Assay; D055598:Chemical Phenomena; D002621:Chemistry; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D011161:Porifera / Q000032:analysis*; D011758:Pyrroles / Q000494:pharmacology*; D011817:Rabbits; D011985:Receptors, Serotonin / Q000187:drug effects* / Q000502:physiology; D013057:Spectrum Analysis
D011758:Pyrroles; D011985:Receptors, Serotonin; C050529:hymenidin