Delayed brainstem auditory evoked responses in experimental diabetes mellitus.
The brainstem auditory evoked responses (BAER) were utilized for the evaluation of central neural transmission in alloxan-induced diabetes in rats. The mean latencies of waves I, III, V and the interpeak latencies III-V and I-V were prolonged in diabetic rats as compared to the same rats before alloxan administration. The incidence of abnormal BAER was more frequent in the group of rats with severe diabetes (82 per cent) than in mildly diabetic animals (42 per cent). Our results may suggest the presence of a central neuropathy in experimental diabetes, which can be detected by the method of BAER.
D000818:Animals; D001300:Audiometry, Evoked Response; D001933:Brain Stem / Q000503:physiopathology*; D002493:Central Nervous System Diseases / Q000175:diagnosis; D003921:Diabetes Mellitus, Experimental / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000175:diagnosis; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors