[Underestimation of bronchial obstruction in sarcoidosis].
We compared the frequency of airway obstruction in 27 patients with pulmonary sarcoidosis using both spirography (FEV1, FEF25-75) and plethysmography (Gus50). FEF25-75 was abnormal in 5 patients and Gus in 8 patients; however, only 3 of them showed abnormal values of both parameters. In the 2 patients with only a spirographic obstruction we observed an increase in static lung compliance. In 5 patients without spirographic obstruction we observed an increase of the elastic recoil of the lung, which probably balanced the decrease of Gus, leading to normal flow. In conclusion, airway obstruction is not frequent in sarcoidosis and can be masked in fibrosing forms, if spirographic measurements only are used.
D000328:Adult; D000403:Airway Resistance; D002248:Carbon Monoxide / Q000097:blood; D005260:Female; D006801:Humans; D008170:Lung Compliance; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D012123:Pulmonary Ventilation; D012507:Sarcoidosis / Q000503:physiopathology*; D013147:Spirometry
D002248:Carbon Monoxide
Sous-estimation de l'obstruction bronchique dans la sarcoïdose.