title: Auditory evoked potentials during isoflurane anaesthesia.
abstract: Brainstem auditory evoked potentials (BAEP) were determined in 12 volunteers. The effect of isoflurane anaesthesia on BAEP was determined in six patients. Body temperature and end-tidal CO2% were controlled. Increasing end-tidal isoflurane concentration from 0.6-2.4% increased BAEP wave I, III and V latencies. The amplitude of wave V decreased with increasing isoflurane concentration. Thus a dose-related change was demonstrated between end-tidal concentration of isoflurane and BAEP latencies.
mesh_terms: D000328:Adult; D000771:Anesthesia, Intravenous; D001306:Auditory Pathways / Q000187:drug effects; D001921:Brain / Q000187:drug effects*; D001933:Brain Stem / Q000187:drug effects; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D009431:Neural Conduction / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects
chemical_list: D007530:Isoflurane