[Dependence of the number of vesicles in vascular smooth muscle cells on the presence of noradrenaline in the extracellular space].
Noradrenaline (NA) effect on the number of vesicles in smooth muscle cells was investigated in small mesenteric arteries of spontaneously hypertensive rats (SHR), aged 8 or 12 weeks, and age-matched normotensive Wistar-Kyoto (WKY) rats. The presence of NA in the incubation medium resulted in an increase in the number of vesicles in SHR of both age groups, but not in WKY. The results are discussed in view of the relationship between the vesicles and Ca transport in smooth muscle cells.
D000818:Animals; D002118:Calcium / Q000378:metabolism; D005110:Extracellular Space / Q000378:metabolism*; D006651:Histocytochemistry; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000378:metabolism / Q000648:ultrastructure*; D009638:Norepinephrine / Q000378:metabolism*; D009940:Organoids / Q000378:metabolism / Q000648:ultrastructure*; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY
D002118:Calcium; D009638:Norepinephrine
Zavisimost' kolichestva vezikul sosudistykh gladkomyshechnykh kletok ot prisutstviia noradrenalina vo vnekletochnoĭ srede.