[Effect of erythrocytes isolated from the blood of animals with experimental tumors on the proliferative activity of cultured tumor cells].
It has been established that erythrocytes taken from blood of mice with experimental tumors being in the active phase of growth, or of mice with a recidivation of the primary tumor intensify proliferative processes in the culture of tumor cells. Erythrocytes from animals with tumors being in the stationary phase of growth did not reveal such a capacity. The authors connect such an effect with the erythrocyte transport function due to which they can store up those factors excreted by tumors which stimulate proliferation. It is supposed that the test defining the peculiarities of the effect of erythrocytes on the proliferative capacity of tumor cells in the tissue culture can be used for the judgement about an individual activity of the growth of primary tumors as well as for the diagnostics of recidivation of tumor growth.
D000818:Animals; D001692:Biological Transport; D002277:Carcinoma / Q000097:blood; D002469:Cell Separation; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002478:Cells, Cultured; D004912:Erythrocytes / Q000502:physiology*; D008545:Melanoma / Q000097:blood; D051379:Mice; D008810:Mice, Inbred C57BL; D009374:Neoplasms, Experimental / Q000097:blood*; D013997:Time Factors
Vliianie éritrotsitov, vydelennykh iz krovi zhivotnykh s éksperimental'nymi opukholiami, na proliferativnuiu aktivnost' kul'tiviruemykh opukholevykh kletok.