Selective streptokinase fibrinolysis in femoro-iliac arterial obstruction.
Percutaneous transluminal angioplasty of iliac and femoral arteries was in 17 patients combined with selective intra-arterial streptokinase treatment. The patients were divided into two groups, one given low dose long-term therapy and the other high dose short-term therapy. The experiences obtained during an observation period of over one year revealed greater benefit from high dose short-term therapy. It seems that the major cause of complications must be attributed to the development of a high level of streptokinase antibodies during low dose long-term therapy.
D000917:Antibody Formation; D001157:Arterial Occlusive Diseases / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D005263:Femoral Artery; D005342:Fibrinolysis; D006801:Humans; D007083:Iliac Artery; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013300:Streptokinase / Q000276:immunology / Q000627:therapeutic use*
D013300:Streptokinase