Polysorbate 80 and low-osmolality water-soluble contrast medium enema in diagnosis and treatment of faecal obstruction in malignant phaeochromocytoma. Report of a case.
Stercoral obstruction in a young woman with disseminated phaeochromocytoma was diagnosed and treated successfully using an enema of isosmolar iohexol (Omnipaque) and 1% polysorbate 80 (Tween 80) without complication. Surgical intervention was thus avoided. A low osmolality water-soluble contrast medium (iohexol 150 mg I/ml) with a wetting agent (1% Tween 80) was used because a barium suspension would have inspissated, exacerbating the constipation and a hyperosmolar contrast medium might have precipitated a hypertensive crisis and destabilized her critical salt and water balance.
D000310:Adrenal Gland Neoplasms / Q000150:complications*; D000328:Adult; D004733:Enema; D005243:Feces; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging* / Q000188:drug therapy; D007463:Iodobenzoates; D007472:Iohexol; D009994:Osmolar Concentration; D010673:Pheochromocytoma / Q000150:complications*; D011136:Polysorbates / Q000627:therapeutic use; D011859:Radiography; D012810:Sigmoid Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy; D014283:Triiodobenzoic Acids / Q000627:therapeutic use
D007463:Iodobenzoates; D011136:Polysorbates; D014283:Triiodobenzoic Acids; D007472:Iohexol