Evaluation of meteneprost potassium (a PGE2 analogue) for cervical dilation and side effects in nonpregnant women.
Meteneprost potassium, a PGE2 analogue, was evaluated in thirty non-pregnant women for use as a prospective cervical dilator and softening agent. No significant change in cervical dilation was noted. A significant relationship between obesity and side effects was observed.
D015064:16,16-Dimethylprostaglandin E2 / Q000031:analogs & derivatives / Q000494:pharmacology* / Q000633:toxicity; D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D001831:Body Temperature / Q000187:drug effects; D002584:Cervix Uteri / Q000187:drug effects / Q000502:physiology*; D004106:Dilatation; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology; D011446:Prospective Studies; D011459:Prostaglandins E, Synthetic / Q000494:pharmacology*; D011674:Pulse / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D013488:Suppositories
D011459:Prostaglandins E, Synthetic; D013488:Suppositories; C025505:meteneprost; D015064:16,16-Dimethylprostaglandin E2