[Regulation of in vitro metabolism of human spongiosa by parathyroid hormone and calcitonin].
A method was developed to investigate in vitro metabolism of human trabecular bone and its hormonal regulation. Human and bovine parathyroid hormone 1-34 caused an increase in the release of calcium and magnesium out of human bone. Human, salmon and porcine calcitonin caused a decrease in the release of calcium and magnesium and inhibited the effect of parathyroid hormone.
D000368:Aged; D000469:Alkaline Phosphatase / Q000378:metabolism; D001842:Bone and Bones / Q000201:enzymology*; D002116:Calcitonin / Q000502:physiology*; D002118:Calcium / Q000378:metabolism; D004573:Electrolytes / Q000378:metabolism*; D004734:Energy Metabolism; D005260:Female; D005270:Femur Head / Q000201:enzymology; D006801:Humans; D006909:Hydroxyproline / Q000378:metabolism; D008274:Magnesium / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000201:enzymology; D010281:Parathyroid Hormone / Q000502:physiology*; D010710:Phosphates / Q000378:metabolism
D004573:Electrolytes; D010281:Parathyroid Hormone; D010710:Phosphates; D002116:Calcitonin; D000469:Alkaline Phosphatase; D008274:Magnesium; D006909:Hydroxyproline; D002118:Calcium
Regulation des in vitro Stoffwechsels menschlicher Spongiosa durch Parathormon und Calcitonin.