title: Vibratory perception thresholds in shipyard workers exposed to solvents.
abstract: Vibratory perception thresholds were determined for 90 subjects working at a shipyard with industrial solvents. The duration of exposure varied from 1 to 44 years (mean 19.6 years). Four of the men but none of women had bilaterally significantly increased thresholds in the lower limbs. In addition, seven subjects had increased thresholds in the upper extremities only. Fifteen subjects were further examined at a neurophysiological laboratory to determine the degree of possible peripheral polyneuropathy. The following measurements were made at the laboratory: motor and sensory conduction velocities, electromyography and heart rate variation during normal and forced breathing. The laboratory investigations revealed abnormalities in most of the subjects with increased vibratory perception thresholds in the lower limbs. On the other hand the laboratory measurements were normal for all subjects with increased thresholds in the upper limbs only. It is concluded that when peripheral polyneuropathy is suspected, quantitative vibratory perception threshold measurement is an easily applicable screening method for selecting subjects for further laboratory investigations.
mesh_terms: D000328:Adult; D000367:Age Factors; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D009784:Occupational Diseases / Q000503:physiopathology*; D010465:Perception / Q000187:drug effects*; D012684:Sensory Thresholds / Q000187:drug effects; D012997:Solvents / Q000009:adverse effects*; D013997:Time Factors; D014732:Vibration
chemical_list: D012997:Solvents