One-stage revision of infected cemented total hip arthroplasty.
A prospective study of a one-stage revision of infected cemented total hip arthroplasty was carried out in 102 consecutive cases using acrylic cement with 0.5 g of gentamicin in each 40 g pack as well as systemic and oral antibiotics. Thirty percent had a sinus tract at some stage before the revision. The most common infecting organism was coagulase-negative Staphylococcus, either as a pure growth or in combination with other organisms. The success rate was 91%, with an average follow-up study of three years and two months. The infection persisted in 9% of the cases. In three cases, infection was correlated with some aspect of the revision technique. The method gave a higher success rate than that obtained without the use of an antibiotic-loaded acrylic cement. Combined systemic and oral use of antibiotics appears to reduce the recurrence rate still further.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001843:Bone Cements / Q000627:therapeutic use*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012086:Reoperation; D013530:Surgical Wound Infection / Q000188:drug therapy*
D000900:Anti-Bacterial Agents; D001843:Bone Cements