Myasthenia gravis caused by penicillamine and chloroquine therapy for rheumatoid arthritis.
We have described a unique patient who had reversible and dose-related myasthenia gravis after penicillamine and chloroquine therapy for rheumatoid arthritis. Although acetylcholine receptor antibodies were not detectable, the time course was consistent with an autoimmune process.
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D002738:Chloroquine / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000139:chemically induced*; D010396:Penicillamine / Q000008:administration & dosage / Q000009:adverse effects*
D002738:Chloroquine; D010396:Penicillamine