Photoallergic and allergic contact dermatitis from dibenzoylmethanes.
Dibenzoylmethanes are widely used in Europe in UVA-absorbing sunscreens. We found that 2 of these, 4-isopropyl-dibenzoylmethane and 4-tert.butyl-4'-methoxy-dibenzoylmethane caused allergic or photoallergic contact dermatitis. This is the first report on allergic and photoallergic reactions caused by dibenzoylmethanes.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001565:Benzoates / Q000009:adverse effects / Q000494:pharmacology*; D047188:Chalcones; D003876:Dermatitis, Atopic / Q000139:chemically induced* / Q000276:immunology; D003877:Dermatitis, Contact / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D011427:Propiophenones; D013473:Sunscreening Agents / Q000009:adverse effects* / Q000494:pharmacology
D001565:Benzoates; D047188:Chalcones; D011427:Propiophenones; D013473:Sunscreening Agents; C049935:avobenzone