[Immediate results of hypoxiradiotherapy of malignant tumors].
The paper represents a comparative analysis of hypoxiradiotherapy of 202 patients with malignant tumors of different sites. A significant decrease (a 3.5-fold) in the number of severe local radiation reactions was noted in hypoxiradiotherapy of cancer of the esophagus, pancreas and metastases of seminoma to the retroperitoneal lymph nodes. A decrease in the number and intensity of general radiation reactions and the absence of pyo-inflammatory complications after radical operations were noted in preoperative large fractionated hypoxiradiotherapy of colon and lung cancer. The general number of radiation reactions was 12% less in hypoxiradiotherapy. Tumor regression after hypoxiradiotherapy did not slow down. Complete or considerable tumor resorption after irradiation against a background of gaseous hypoxia was noted in 74 +/- 7% of the patients and in 65 +/- 7% after radiotherapy alone. Hypoxiradiotherapy alone or before operation should be widely introduced into clinical practice of cancer dispensaries or radiological departments.
D000328:Adult; D000368:Aged; D004938:Esophageal Neoplasms / Q000532:radiotherapy; D006801:Humans; D008875:Middle Aged; D009369:Neoplasms / Q000532:radiotherapy*; D010100:Oxygen / Q000494:pharmacology*; D010190:Pancreatic Neoplasms / Q000532:radiotherapy; D011832:Radiation Injuries / Q000517:prevention & control; D011838:Radiation-Sensitizing Agents; D012186:Retroperitoneal Neoplasms / Q000532:radiotherapy
D011838:Radiation-Sensitizing Agents; D010100:Oxygen
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