Differences in IgG1 and IgG2 responses of cattle infected with Coxiella burnetii and following vaccination.
Vaccination of 115 cattle with a formalin-inactivated Coxiella burnetii (Phase II) vaccine selectively induced a highly significant IgG2 response detectable by enzyme-linked immunosorbent assay. High IgG2 and negative or cut off IgG1 levels could be detected in uninfected cattle, whereas significant IgG1 but lower IgG2 levels were associated with C. burnetii infections.
D000818:Animals; D000917:Antibody Formation; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis / Q000145:classification*; D007700:Kinetics; D011778:Q Fever / Q000276:immunology / Q000662:veterinary*; D014611:Vaccination
D007074:Immunoglobulin G