title: [Changes in the myocardium of fetuses and newborn infants as a result of hypoxia].
abstract: Myocardium has been investigated in 68 human fetuses and newborns suffered from intrauterine acute and prolonged hypoxia, occurred as a result of various maternal, fetal and placental diseases. Under acute hypoxia only reactive changes of the contractile myocardium appear. They are demonstrated as degeneration of muscle fibers and appearance of scattered foci of necrosis in cardiomyocytes. Under a prolonged hypoxia, besides analogous reactive changes, compensatory hypertrophy of some part of cardiomyocytes is noted; this is manifestation of a compensatory-adaptive reaction of the myocardium.
mesh_terms: D001238:Asphyxia Neonatorum / Q000378:metabolism / Q000473:pathology*; D003331:Coronary Vessels / Q000473:pathology; D005260:Female; D005311:Fetal Hypoxia / Q000378:metabolism / Q000473:pathology*; D006003:Glycogen / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006801:Humans; D008833:Microcirculation / Q000473:pathology; D009206:Myocardium / Q000378:metabolism / Q000648:ultrastructure*; D011247:Pregnancy
chemical_list: D006025:Glycosaminoglycans; D006003:Glycogen
vernacular_title: Izmeneniia miokarda u plodov i novorozhdennykh deteĭ v usloviiakh gipoksii.