Improved sperm counts in mink males (Mustela vison) treated with clomiphene citrate.
A group of 12 sterile, azoospermic mink males were treated with clomiphene citrate (10 mg/kg/day) for 10 days during the mating season; 50% of the males showed improved sperm counts already after 2 days of treatment and the maximum effect was seen 4-6 days after the start of the treatment. The other half of the group did not respond to the treatment and their sperm counts remained near zero during the whole experiment.
D000818:Animals; D002996:Clomiphene / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D007248:Infertility, Male / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008907:Mink / Q000502:physiology*; D009845:Oligospermia / Q000188:drug therapy / Q000503:physiopathology; D013076:Sperm Count / Q000187:drug effects*
D002996:Clomiphene