Hydration properties and structure of phosphatidylcholine membranes in the presence of n-nonyl bromide.
Interaction of chemical fusogen n-nonyl bromide with a model membrane formed from phosphatidylcholine was studied using 2D-NMR spectra of heavy water and 31P-NMR proton decoupled spectra of the lipid phosphate group in multilamellar lipid dispersions. n-Nonyl bromide was found to influence the hydration layer of the model membrane. No participation of phosphatidylcholine molecules in non-bilayer configurations of the membrane was observed.
D003903:Deuterium; D006842:Hydrocarbons, Brominated / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008563:Membrane Lipids / Q000378:metabolism; D008961:Models, Structural; D010713:Phosphatidylcholines / Q000378:metabolism*; D010761:Phosphorus Radioisotopes; D014867:Water / Q000502:physiology*
D006842:Hydrocarbons, Brominated; D008563:Membrane Lipids; D010713:Phosphatidylcholines; D010761:Phosphorus Radioisotopes; D014867:Water; C050237:n-nonyl bromide; D003903:Deuterium