title: Murine erythroblasts do not contain histone H10.
abstract: Histone H10, which is related to the avian erythrocyte-specific histone H5, is known to accumulate in the chromatin of differentiating murine erythroleukemia cells. However, H10 was less than approximately 1% of the H1 in the spleens of anemic or pregnant mice even when as many as 65% of the cells in the spleens were nucleated erythroid cells. The H1 complement of erythroid spleens was nevertheless quite different from that of normal spleens. I conclude that H10 has no major role in normal erythroid development in mammals.
mesh_terms: D000740:Anemia / Q000097:blood; D000818:Animals; D004900:Erythroblasts / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D010659:Phenylhydrazines / Q000494:pharmacology; D010750:Phosphoproteins / Q000097:blood; D013154:Spleen / Q000378:metabolism
chemical_list: D006657:Histones; D010659:Phenylhydrazines; D010750:Phosphoproteins; C030299:phenylhydrazine