[Dynamics of various characteristics of the sympathetic ganglia of animals subjected to chemical sympathectomy at high altitude].
The effect of high altitude hypoxia on the sympathetic nervous system was studied on desympathized rats. The degree of the sympathetic ganglion neurons destruction and catecholamine fluorescence were determined. The investigation showed an increase of catecholamine fluorescence in sympathetic ganglia in high altitude adaptation. 30-day administration of sympatholytic guanethidine at high altitude results in destruction of less ganglion neurons than at low altitude. At high altitude the rate of fluorescence of biogenic amines in unaffected cells remains high. After partial desympathization (7 days), the rate of neuron destruction diminishes and biogenic amines fluorescence increases along with the duration of preliminary adaptation.
D000222:Adaptation, Physiological; D000531:Altitude; D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D005728:Ganglia, Sympathetic / Q000378:metabolism / Q000502:physiology*; D006145:Guanethidine; D008297:Male; D008856:Microscopy, Fluorescence; D051381:Rats; D013563:Sympathectomy, Chemical
D002395:Catecholamines; D006145:Guanethidine
Dinamika nekotorykh kharakteristik simpaticheskikh gangliev zhivotnykh, podvergnutykh khimicheskoĭ desimpatizatsii v usloviiakh vysokogor'ia.