Radiation-induced intracranial fibrochondrosarcoma.
A 50-year-old patient developed a left temporal fibrochondrosarcoma 27 years after radiation therapy for a suspected pituitary adenoma. The long latency between the irradiation and the development of the sarcoma and the histological nature of the tumour are unusual features for a malignant radiation-induced intracranial tumour. The histogenesis of fibrochondrosarcoma of the brain is discussed.
D000236:Adenoma / Q000532:radiotherapy; D001932:Brain Neoplasms / Q000209:etiology*; D002813:Chondrosarcoma / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D010910:Pituitary Irradiation / Q000009:adverse effects*; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D013702:Temporal Lobe