[Effect of phosphocreatine on the incidence of ventricular heart rhythm disorders in the 1st 24 hours of myocardial infarct].
Twenty-four-hour Holter ECG monitoring was conducted in 60 patients with acute myocardial infarction. Thirty patients received 2-hour intravenous creatine phosphate (CP) infusions at the rate of 4 g/hour, and the other 30 patients were taken as controls. The CP treatment was shown to reduce the incidence of ventricular arrhythmias within the first day of the attack. CP-treated patients showed significantly reduced incidence of paired extrasystoles, bigeminyes, early R-to-T extrasystoles and ventricular tachycardias, as compared to the controls.
D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000453:epidemiology / Q000517:prevention & control*; D004341:Drug Evaluation; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D010725:Phosphocreatine / Q000627:therapeutic use*; D013997:Time Factors
D010725:Phosphocreatine
Vliianie fosfokreatina na chastotu zheludochkovykh narusheniĭ ritma serdtsa v 1-e sutki infarkta miokarda.