[Association of acromegaly and a cerebral arterial aneurysm disclosed by a subarachnoid hemorrhage].
The association of acromegaly and cerebral aneurysm is an infrequent clinical finding, being few the cases reported in literature. A major incidence of cerebral aneurysm in patients with other pituitary adenoma and cerebral tumour has been described, in relation to the general population. We have studied a male patient, aged 37 years old, with an acromegaly disease initiated 5 years before, that came to our hospital because of subarachnoid hemorrhage symptomatology. A right middle cerebral aneurysm was found in surgery. Hormonal studies confirmed a high basal Growth Hormone (64 ng/ml) that was not suppressed during an Oral Glucose Tolerance Test (75 g). A triple stimulus test (Insulin, TRH, LHRH) demonstrated non-response of GH to TRH and hypoglycemia others hormones were normal. Radiological studies were suggestive of Acromegaly disease. Computed axial tomography showed an intra-sellar tumour. The patient was operated (Transsphenoidal surgery) and a GH pituitary secreting tumour found, without suprasellar extension. The clinical significance and importance of the coexistence of the Acromegaly and Cerebral Aneurysm is discussed, with a review of hypothesis implicated.
D000172:Acromegaly / Q000150:complications* / Q000503:physiopathology; D000328:Adult; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000503:physiopathology; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000378:metabolism; D013345:Subarachnoid Hemorrhage / Q000209:etiology*
Association d'une acromégalie et d'un anévrysme artériel cérébral révélé par une hémorragie sous-arachnoïdienne.