title: [Preoperative preparation with plasmapheresis of patients with diffuse toxic goiter and intolerance to antithyroid drugs].
abstract: The authors analysed the results of therapy with plasmapheresis of 46 patients with diffuse toxic goiter showing intolerance to antithyroid therapy for the purpose of preoperative preparation. A therapeutic effect was achieved in 45 patients. Plasmapheresis resulted in the reduction of a period of preoperative preparation, the concentration of T4 and JgG, IgA and IgM decreased and the TTH level increased.
mesh_terms: D004342:Drug Hypersensitivity; D005260:Female; D006111:Graves Disease / Q000276:immunology / Q000601:surgery*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008713:Methimazole / Q000009:adverse effects; D008875:Middle Aged; D010956:Plasmapheresis; D011300:Preoperative Care; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: D007136:Immunoglobulins; D008713:Methimazole; D013972:Thyrotropin; D013974:Thyroxine
vernacular_title: Predoperatsionnaia podgotovka plazmaferezom bol'nykh diffuznym toksicheskim zobom s neperenosimost'iu sntitireoidnykh preparatov.