title: Eel electric organ: hyperexpressing calmodulin system.
abstract: The electroplax of the electric eel Electrophorus electricus is the most abundant source of the calcium-binding protein calmodulin. The electroplax has 250 times the amount of calmodulin and its mRNA than eel skeletal muscle. Our data suggest that there is no major difference in gene copies, the degree of methylation, or genome rearrangement of the calmodulin gene in DNAs from eel electroplax and muscle. Differences in the calmodulin-binding proteins in electroplax and muscle suggest a differential role for the functional expression of calmodulin in cellular regulation.
mesh_terms: D000818:Animals; D002147:Calmodulin / Q000235:genetics*; D004557:Electric Organ / Q000378:metabolism*; D004593:Electrophorus; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D009693:Nucleic Acid Hybridization; D009928:Organ Specificity; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic
chemical_list: D002147:Calmodulin; D012333:RNA, Messenger