title: Paracentric inversions in human chromosome 7.
abstract: A paracentric inversion (7)(q11q22) and mosaicism 46,XX/45,X was detected in a female with minor malformations. The same inversion was observed in the mother of the patient. The analysis of high resolution banded chromosomes revealed no visible imbalance in the inverted long arm of the chromosome 7. All published cases of paracentric inversions in the human chromosome 7 are reviewed and the relationship between this inversion and the occurrence of an aneuploidy of the sex chromosomes is discussed.
mesh_terms: D000293:Adolescent; D002503:Centromere; D007446:Chromosome Inversion; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D009030:Mosaicism; D014424:Turner Syndrome / Q000235:genetics