[Antiviral action of lysolecithin analogs against human pathogenic viruses].
The virucidal effect, the inhibition of virus adsorption and penetration and the influence on later phases of replication of human pathogenic viruses were studied. The compounds showed a significant virucidal effect to enveloped viruses (measles virus, herpes virus type 1 and 2), whereas the compounds were ineffective against nonenveloped viruses (Coxsackie virus A9 and B1, attenuated poliovirus type 1, adenovirus type 1). Interactions with the viral envelope are supposed.
D000998:Antiviral Agents; D002470:Cell Survival / Q000187:drug effects*; D002478:Cells, Cultured; D006801:Humans; D008244:Lysophosphatidylcholines / Q000494:pharmacology*; D014780:Viruses / Q000187:drug effects
D000998:Antiviral Agents; D008244:Lysophosphatidylcholines
Antivirale Wirkung von Lysolecithin-Analoga auf humanpathogene Viren.