[Formation of microfilament bundles in the tumor cell interphase nuclei of a rat neurinoma exposed to dimethyl sulfoxide].
The action of 15% dimethyl sulfoxide (DMSO) on the ultrastructure of the rat neurinoma cells (line NGUK-I) has been studied. The agent induced the formation of microfilament bundles in interphase nuclei after 30-60 min of treatment. The microfilament bundles revealed are suggested to be actin.
D008841:Actin Cytoskeleton / Q000187:drug effects* / Q000648:ultrastructure; D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects* / Q000648:ultrastructure; D002478:Cells, Cultured; D003599:Cytoskeleton / Q000187:drug effects*; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D005726:Ganglia, Parasympathetic; D007399:Interphase / Q000187:drug effects*; D009442:Neurilemmoma / Q000188:drug therapy* / Q000648:ultrastructure; D051381:Rats
D004121:Dimethyl Sulfoxide
Formirovanie tiazheĭ mikrofilamentov v interfaznykh iadrakh opukholevykh kletok nevrinomy krysy pri deĭstvii dimetilsul'foksida.