Primary perianal actinomycosis over a thirty year period.
A 50-year-old Japanese man had had abscesses and draining fistulas in the perianal region. These lesions recurred, despite surgical treatment such as incision and drainage over a 30 year period. "Sulfur granules" were found in the pus from the abscess and Actinomyces israelii was cultured. Ampicillin-cloxacillin treatment lead to healing. The patient died 4 months later with a hepatoma and multiple metastases.
D000038:Abscess / Q000209:etiology; D000196:Actinomycosis / Q000175:diagnosis* / Q000188:drug therapy; D000667:Ampicillin / Q000627:therapeutic use; D001004:Anus Diseases / Q000175:diagnosis* / Q000188:drug therapy; D003023:Cloxacillin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D012003:Rectal Fistula / Q000209:etiology; D013997:Time Factors
D000667:Ampicillin; D003023:Cloxacillin