The interactions of 1-palmitoyl-2-oleylphosphatidylcholine and bovine brain cerebroside.
Model membranes composed of 1-palmitoyl-2-oleylphosphatidylcholine (POPC) and bovine brain galactocerebroside (BOV-CER) have been studied by differential scanning calorimetry (DSC). POPC is a naturally occurring phospholipid, and BOV-CER is a major component of the myelin membrane. POPC and BOV-CER are immiscible in the gel state over the composition range 0-70 mol% BOV-CER. At most POPC/BOV-CER ratios, broad dual-peaked acyl chain transitions are observed, characteristic of the co-existence of a fluid POPC-rich liquid-crystalline phase and a solid BOV-CER-rich gel phase over a wide temperature range.
D000818:Animals; D001923:Brain Chemistry; D002151:Calorimetry; D002417:Cattle; D002554:Cerebrosides / Q000378:metabolism*; D005782:Gels; D008560:Membrane Fluidity; D008567:Membranes, Artificial; D010713:Phosphatidylcholines / Q000378:metabolism*
D002554:Cerebrosides; D005782:Gels; D008567:Membranes, Artificial; D010713:Phosphatidylcholines; C028694:1-palmitoyl-2-oleoylphosphatidylcholine