[Study of factors determining the clonogenic capacity of irradiated cells by computer simulation].
The methods of the multifactor disperse analysis of the results of studies of the simulation model of the effect of ionizing radiation on cell populations were used to study the role of some characteristics of the stationary culture in its response to a single radiation effect. The clonogenic capacity of cells was used as a criterion for assessing the biological effect of radiation. "The share of resting cells" was a predominant factor influencing the survival of irradiated cell populations.
D000818:Animals; D002453:Cell Cycle / Q000528:radiation effects*; D002478:Cells, Cultured; D002999:Clone Cells / Q000528:radiation effects; D003201:Computers; D008954:Models, Biological; D011836:Radiation Tolerance
Issledovanie faktorov, opredeliaiushchikh klonogennuiu sposobnost' obluchennykh kletok, metodami imitatsionnogo modelirovaniia na EVM.