title: Soft-tissue infection in lower extremity trauma.
abstract: Soft-tissue infection following lower extremity trauma has not been studied in detail in light of recent data on biology of infection. This article examines specific problems in lower extremity trauma that allow the wound to become susceptible to wound infection. It also illustrates the various principles of wound management in lower extremity trauma that serve to prevent infection. Two case examples are used to illustrate principles of management. Other wound problems in lower extremity trauma are also discussed, such as rabies, necrotizing soft-tissue infection, tetanus, and diabetic foot infections.
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement; D048909:Diabetes Complications; D005260:Female; D005534:Foot Diseases / Q000517:prevention & control; D006801:Humans; D007108:Immune Tolerance; D007869:Leg Injuries / Q000382:microbiology / Q000628:therapy*; D008297:Male; D011818:Rabies / Q000517:prevention & control; D013524:Surgical Flaps; D013742:Tetanus / Q000517:prevention & control; D013745:Tetanus Toxoid; D014946:Wound Infection / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents; D013745:Tetanus Toxoid