title: [A spectrophotometric micromethod for the study of theophylline pharmacokinetics in children with bronchial asthma].
abstract: A spectrophotometric micromethod for determination of theophylline in the blood is proposed. Theophylline pharmacokinetics was studied by the method in 71 children with bronchial asthma. Doses and the number of administrations were selected individually for 45 patients under control of blood plasma theophylline concentration. Good clinical results were obtained.
mesh_terms: D000293:Adolescent; D000628:Aminophylline / Q000008:administration & dosage / Q000097:blood; D001249:Asthma / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007223:Infant; D007700:Kinetics; D008297:Male; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013806:Theophylline / Q000008:administration & dosage / Q000097:blood*; D013997:Time Factors
chemical_list: D000628:Aminophylline; D013806:Theophylline
vernacular_title: Issledovanie spektrofotometricheskim mikrometodom farmakokinetiki teofillina u deteĭ s bronkhial'noĭ astmoĭ.