[Effect of the delta-sleep peptide on parasympathetic regulation of the cardiac rhythm].
Effect of delta-sleep peptide (60 nM/kg) on the parasympathetic regulation of cardiac activity has been studied in the experiments on rabbits. It has been established that intravenous administration of this peptide to voluntary-behaving animals results in heart rate reduction by an average of 16%, that can be eliminated by atropine. Delta-sleep peptide has been demonstrated to intensify negative chronotropic effect in the case of directly irritated wandering nerve. The data obtained explain a protective effect of delta-sleep peptide on the heart under emotional stress.
D000818:Animals; D003701:Delta Sleep-Inducing Peptide; D003864:Depression, Chemical; D004558:Electric Stimulation; D006339:Heart Rate / Q000187:drug effects*; D009842:Oligopeptides / Q000494:pharmacology*; D010275:Parasympathetic Nervous System / Q000187:drug effects*; D011817:Rabbits; D013997:Time Factors; D014630:Vagus Nerve / Q000502:physiology
D009842:Oligopeptides; D003701:Delta Sleep-Inducing Peptide
Vliianie peptida del'ta-sna na parasimpaticheskuiu reguliatsiiu serdechnogo ritma.