title: Allele and locus classification in electrophoretic population studies.
abstract: The electrophoretic separation of protein variants having slightly different mobilities is a basic tool of biochemical population genetics. In certain situations it is difficult to determine how to classify the variants as alleles of a number of genetic loci, that is, as variant subsets within each of which the Mendelian laws hold. In this article, we develop and analyze a series of algorithms for solving various versions and generalizations of this problem of optimal classification.
mesh_terms: D000483:Alleles; D004586:Electrophoresis; D005796:Genes; D006801:Humans; D011153:Population; D011506:Proteins
chemical_list: D011506:Proteins