Thyroid function and the incidence of breast cancer in Hawaiian, British and Japanese women.
Serum-free thyroxine (FT4) concentrations are lower in Hawaiian and Hawaiian Caucasian women than in Hawaiian Japanese, Hawaiian Filipino, Hawaiian Chinese, and English and Japanese mainland women. There is a high inverse correlation between FT4 and risk of breast cancer in these ethnic groups. Thyroid-stimulating hormone (TSH) concentrations, which are inversely correlated with FT4, generally show the same relationship.
D000328:Adult; D001835:Body Weight; D001943:Breast Neoplasms / Q000453:epidemiology*; D005260:Female; D006254:Hawaii; D006801:Humans; D007564:Japan; D008875:Middle Aged; D012306:Risk; D012709:Serum Albumin / Q000032:analysis; D013961:Thyroid Gland / Q000502:physiology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D006113:United Kingdom
D012709:Serum Albumin; D013972:Thyrotropin; D013974:Thyroxine