Chromatographic analysis of gastrin-releasing peptide in heat-inactivated fetal calf serum.
Gastrin-releasing peptide and the carboxyterminal fragments gastrin-releasing peptide [14-27] and [18-27] are found by radioimmunology and high performance liquid chromatography to be present in heat-inactivated fetal calf sera. Peptides containing the carboxyterminal sequence of gastrin-releasing peptide are known to display mitogenic activity. Thus, gastrin-releasing peptide represents a new class of mitogenic factors that are present in heat-inactivated fetal calf serum.
D000818:Animals; D001769:Blood; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D003470:Culture Media; D005333:Fetus; D019886:Gastrin-Releasing Peptide; D006358:Hot Temperature; D010446:Peptide Fragments / Q000032:analysis; D010455:Peptides / Q000032:analysis*; D011863:Radioimmunoassay
D003470:Culture Media; D010446:Peptide Fragments; D010455:Peptides; D019886:Gastrin-Releasing Peptide; C041922:gastrin releasing peptide (14-27)