title: [Formation of pollen-induced allergy in guinea pigs after specific immunotherapy with a bacterial allergen].
abstract: The investigation was aimed at elucidating the process of the development of allergy to exoallergens (e.g., to linear-leaf wormwood pollen) in the body after desensitization by specific immunotherapy (SIT) with heterologous (staphylococcal) allergen. The study revealed that in staphylococcal allergy the subsequent development of pollen sensitization occurred with greater intensity, and SIT was found to exert no influence on this process. For the first time pollen allergy was found to produce an unfavorable effect on the quality and effectiveness of SIT with heterologous staphylococcal allergen, this effect consisting in the acceleration and intensification of the process leading to the recovery of sensitization to staphylococci. The importance of measures for limiting contacts with heterologous allergens and their elimination during SIT is emphasized.
mesh_terms: D000485:Allergens / Q000276:immunology*; D000818:Animals; D003888:Desensitization, Immunologic / Q000379:methods; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000209:etiology* / Q000276:immunology; D007114:Immunization; D007167:Immunotherapy; D011058:Pollen / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology*
chemical_list: D000485:Allergens
vernacular_title: Formirovanie pyl'tsevoĭ allergii u morskikh svinok posle spetsificheskoĭ immunoterapii bakterial'nym allergenom.