Long-term changes in inhalant allergy in asthmatic children.
In a representative cohort of 55 asthmatic schoolchildren the progress of the allergy per se was followed up prospectively for 8 years. Judged by clinical data, skin prick tests and RAST, a large majority of the children retained their allergies to pollen and animal danders. These allergens were predominant, whereas allergy to mites and moulds was less frequent. Serum IgE levels showed a strong tendency to remain high. Positive RAST and skin prick tests were also found in a substantial number of children with normal serum IgE concentrations.
D000293:Adolescent; D000375:Aging / Q000276:immunology*; D000818:Animals; D000906:Antibodies / Q000276:immunology; D001249:Asthma / Q000097:blood / Q000175:diagnosis / Q000276:immunology / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis / Q000276:immunology; D008297:Male; D011058:Pollen / Q000276:immunology; D011446:Prospective Studies; D011852:Radioallergosorbent Test; D012130:Respiratory Hypersensitivity / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology; D012867:Skin / Q000276:immunology; D012882:Skin Tests
D000906:Antibodies; D007073:Immunoglobulin E