[Radiation protection effectiveness of various zootoxins].
A study was made of the effectiveness of a new class of radioprotective agents, polypeptides, obtained from zootoxins of scorpion, tarantula, Lathrodectes tredecimguttatus, and bee under conditions of a short-term and long-term irradiation. The peptide fraction of the scorpion venom, butoxin, was most radioprotective: it provided 65% survival after LD98/30. Butoxin exerted a stimulatory effect on the hypophysis-adrenal system and haemopoiesis of intact and irradiated animals.
D000302:Adrenal Cortex / Q000503:physiopathology; D000818:Animals; D001514:Bee Venoms / Q000627:therapeutic use*; D005260:Female; D006168:Guinea Pigs; D006410:Hematopoiesis / Q000187:drug effects / Q000528:radiation effects; D008297:Male; D008555:Melitten / Q000627:therapeutic use*; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000503:physiopathology / Q000517:prevention & control*; D011837:Radiation-Protective Agents; D012604:Scorpion Venoms / Q000627:therapeutic use*; D013154:Spleen / Q000473:pathology
D001514:Bee Venoms; D011837:Radiation-Protective Agents; D012604:Scorpion Venoms; D008555:Melitten
Radiozashchitnaia éffektivnost' nekotorykh zootoksinov.