[Effect of papain and levamisole on the body's immunological indices and oxidation-reduction processes in experimental sensitization].
The effect of papain on sensitized animals was evident from activation of oxidation processes in the liver and adrenal glands, increased ability of the host to develop cellular immunity reactions, a moderate decrease in the level of humoral antibodies and inactivation of the monooxygenase system of the liver and adrenal glands. Levamisol had a favourable effect on the immunological reactions and monooxygenase system. However, it induced an increase in tissue hypoxia of the organs.
D000311:Adrenal Glands / Q000187:drug effects / Q000201:enzymology; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000937:Antigen-Antibody Reactions / Q000187:drug effects*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D006168:Guinea Pigs; D007111:Immunity, Cellular / Q000187:drug effects; D007114:Immunization / Q000379:methods; D007978:Levamisole / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D010084:Oxidation-Reduction / Q000187:drug effects; D010206:Papain / Q000494:pharmacology*
D007978:Levamisole; D003577:Cytochrome P-450 Enzyme System; D010206:Papain
Vliianie papaina i levamizola na immunologicheskie pokazateli i okislitel'no-vosstanovitel'nye protsessy organizma v usloviiakh éksperimental'noĭ sensibilizatsii.