The structures of the novel protein kinase C inhibitors K-252a, b, c and d.
The structures of four new protein kinase C inhibitors of microbial origin, K-252a, b, c and d were determined by spectral studies and chemical conversion.
D002227:Carbazoles; D055598:Chemical Phenomena; D002621:Chemistry; D026121:Indole Alkaloids; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*
D002227:Carbazoles; D026121:Indole Alkaloids; C049985:staurosporine aglycone; D011493:Protein Kinase C