[Synthesis of thioanalogs of platelet activating factor (PAF)].
Synthesis of thioalkyl, thioacetyl and phosphothionyl PAF analogues was carried out starting with corresponding monoalkyl glycerol ethers. The synthetic route was based on preparation of racemic phosphatidylcholines and subsequent hydrolysis with phospholipase A2 to afford isomers having natural configuration.
D055598:Chemical Phenomena; D002621:Chemistry; D010741:Phospholipases A; D054467:Phospholipases A2; D010972:Platelet Activating Factor / Q000031:analogs & derivatives / Q000138:chemical synthesis
D010972:Platelet Activating Factor; D010741:Phospholipases A; D054467:Phospholipases A2
Sintez tioanalogov faktora aktivatsii trombotsitov (FAT).