[Immunochemical study of antigens in the ascitic fluid of patients with ovarian cancer].
5 antigens are identified in ascitic fluid from patients with ovarian tumours--AgA, AgB, AgV, AgG and AgD. Specific antisera are produced in rabbits by immunization with different protein and glycoprotein fractions of this fluid and by simultaneous injections of gamma-globulin fraction from antihuman plasma protein and pool of 25 ascitic fluids to rabbits. By the double immunodiffusion technique with standard test-systems for these antigens. It is found that all of them are absent in donor blood serum, but are present in certain normal and fetal tissues. AgA and AgD are also found in some extracts of lung, stomach, colon, and connective tissue tumours. The immunohistochemical and high-sensitive serological methods are necessary for determination of the usefulness of these antigens as tumour markers.
D000951:Antigens, Neoplasm / Q000032:analysis*; D001202:Ascitic Fluid / Q000276:immunology*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000276:immunology*
D000951:Antigens, Neoplasm
Immunokhimicheskoe izuchenie antigenov v astsitnoĭ zhidkosti pri rake iachnikov u cheloveka.