[Functional study of gastroesophageal reflux in children with brain diseases].
Aiming to evaluate the participation of oesophageal motor troubles in the pathogeny of gastro-oesophageal reflux in brain-damaged children, we have studied 16 of these patients. Most of them had a more or less severe esophagitis due to excessive acid exposure. We have found a decreased LESP as compared to normal subjects (8.84 +/- 6.20 vs. 18.33 +/- 6.55 mmHg (p less than 0.001)), and high percentages of non-propulsive waves in basal conditions (70 +/- 29.66 vs. 6.25 +/- 9.16 (p less than 0.001)) as well as after serum (66.33 +/- 28.06 vs. 16.66 +/- 13.66 (p less than 0.001) and acid instillation (58.33 +/- 28.91 vs. 26.41 +/- 12.04 (p less than 0.05)). These results demonstrate that motor disturbances are responsible for the severity of GER in this group of patients.
D000293:Adolescent; D001927:Brain Diseases / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D004724:Endoscopy; D004943:Esophagogastric Junction / Q000503:physiopathology; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D008365:Manometry; D012189:Retrospective Studies
Etude fonctionelle du reflux gastro-oesophagien chez les enfants encéphalopathes.