[Results of treatment of lymphosarcomas with primary involvement of the peritoneal and mesenteric lymph nodes].
A total of 105 lymphosarcoma patients with primary involvement of retroperitoneal and mesenterial lymph nodes (aged 17 to 77) were examined. Diagnosis was verified on morphology. Chemo- and radiotherapy was administered to 35 (33.3%) patients, chemotherapy alone to 34 (32.3%), combined therapy (surgery combined with radio- and drug therapy) to 20 (19%) patients, gamma-beam therapy to 16 (15.2%) patients. Remissions were achieved in 85.7% of the patients, of them complete remissions in 51.4% of the patients. Seventy patients were followed up prior to recurrences. In 54.2% of the patients recurrences manifested themselves in the generalization of tumor process with involvement of distant peripheral lymph nodes as well as extranodal organs within 1 year of remission irrespective of therapeutic methods. Local recurrences were noted in 73.9% of the patients on chemotherapy. Lymphosarcoma generalization was found in 63.6% of the patients receiving chemotherapy. A 5-year recurrence-free period was noted in 28.5% of the patients receiving combined therapy.
D000293:Adolescent; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000628:therapy*; D008297:Male; D008643:Mesentery; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010534:Peritoneal Neoplasms / Q000628:therapy*; D011379:Prognosis
Rezul'taty lecheniia limfosarkom s pervichnym porazheniem zabriushinnykh i bryzheechnykh limfaticheskikh uzlov.