title: African swine fever. I. Morphological changes and virus replication in blood platelets of pigs infected with virulent haemadsorbing and non-haemadsorbing isolates.
abstract: Replicating and mature viral particles were detected with the transmission electron microscope in blood platelets of pigs infected with virulent haemadsorbing and non-haemadsorbing African swine fever virus isolates. Although platelet numbers decreased terminally in infected pigs, the most noticeable morphological damage to these cells apparent in the last 2 days of the disease included cytoplasmic swelling, vacuolation, fragmentation and loss of dense granules.
mesh_terms: D000357:African Swine Fever / Q000097:blood* / Q000382:microbiology; D000358:African Swine Fever Virus / Q000502:physiology / Q000648:ultrastructure; D000818:Animals; D001792:Blood Platelets / Q000382:microbiology / Q000648:ultrastructure*; D003588:Cytopathogenic Effect, Viral; D010976:Platelet Count; D013552:Swine; D014779:Virus Replication