Contact sensitivity to proflavine.
Proflavine lotion is a commonly used topical antiseptic in the tropics, but its sensitizing potential was never emphasized and many who developed allergic contact dermatitis were never aware of it. In a study of 45 patients, most presented with acute or subacute dermatitis which started on the arms and legs. Concomitant cutaneous sensitivity to other medicaments and lanolin occurred in 66% of the patients.
D000166:Acridines / Q000009:adverse effects*; D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D010328:Patch Tests; D011370:Proflavine / Q000009:adverse effects*; D011446:Prospective Studies
D000166:Acridines; D000891:Anti-Infective Agents, Local; D011370:Proflavine