title: Ethmoiditis-associated periorbital cellulitis.
abstract: Seventy-two children with periorbital cellulitis were followed prospectively during a 30-month study period. Twenty patients (28%) had mucopurulent rhinorrhea with obvious radiological ipsilateral opacity of the ethmoid sinuses. This group of patients, as opposed to patients with periorbital cellulitis and no associated ethmoiditis, is characterized by the following features: Higher incidence of temperature greater than 38.5 degrees C (16/20 vs 24/52. P less than 0.01) and elevated white blood count greater than 15,000 cells/mm3 on admission (10/20 vs 5/52. P less than 0.001). Delayed recovery (6.7 +/- 3.4 vs 3.4 +/- 1.6 days. P less than 0.001). Higher rate of recurrent periorbital cellulitis with associated ethmoiditis within 6 months of follow-up (5/20 vs 1/52. P less than 0.01). This ethmoiditis-associated serious form of periorbital cellulitis requires an aggressive treatment regimen and a prolonged follow-up.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000150:complications* / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D005005:Ethmoid Sinus / Q000382:microbiology; D005260:Female; D006192:Haemophilus Infections / Q000188:drug therapy; D006801:Humans; D007223:Infant; D008297:Male; D009916:Orbital Diseases / Q000150:complications* / Q000382:microbiology; D011446:Prospective Studies; D012852:Sinusitis / Q000150:complications* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents