Metastatic trichomatricial carcinoma.
Trichomatricial carcinoma has been recently recognized as a rare malignant variant of pilomatricoma with a potential for local recurrence and, rarely, for distant metastases. We describe such a tumor in a 52-year-old man who developed local recurrence and axillary lymph node metastases within six months of local excision, followed by bilateral pulmonary metastases and 2 1/2 years later by death due to disseminated tumor. This, to our knowledge, is the second reported case of metastasizing trichomatricial carcinoma.
D002277:Carcinoma / Q000473:pathology / Q000556:secondary*; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D012878:Skin Neoplasms / Q000473:pathology*