[Is there a hyporeactivity of the vascular wall to atherogenic risk factors?].
The hypothesis is promoted that the arterial vessel can modulate the response to atherogenic factors. Patients with the same index of atherogenic factor may have different degrees of arteriosclerosis. The verification of this thesis needs a prospective study. The second fact described is the diminished experimental arteriosclerosis after treatment with the calcium antagonist Nifedipine (Corinfar).
D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001012:Aorta, Abdominal / Q000473:pathology; D001013:Aorta, Thoracic / Q000473:pathology; D001161:Arteriosclerosis / Q000473:pathology* / Q000517:prevention & control; D004727:Endothelium / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000473:pathology*; D009543:Nifedipine / Q000008:administration & dosage; D011817:Rabbits; D012306:Risk
D009543:Nifedipine
Gibt es eine Hyporeaktivität der Gefässwand auf atherogene Risikofaktoren?