Paecilomyces lilacinus cellulitis in an immunocompromised patient.
Paecilomyces lilacinus, a saprophytic soil fungus, is an uncommon human pathogen. An immunocompromised patient developed a deep cellulitis due to P lilacinus. The infection responded poorly to intravenous amphotericin B but eventually resolved after combination therapy with amphotericin B and flucytosine (5-fluorocytosine). Previous in vitro studies have suggested that miconazole is the most active antifungal agent against P lilacinus.
D002481:Cellulitis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D008875:Middle Aged; D009181:Mycoses; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology*; D010143:Paecilomyces