title: [Characteristics of the generation of transmembrane current higher harmonics in lipid bilayers in glycerol and 1,2-propane diol solutions].
abstract: It is shown that structural rearrangements of bilayer lipid membrane induced by glycerol and 1,2-propane diol result in noncompensated second harmonic of transmembrane current having quadratic dependence on input voltage and a weak dependence on frequency. The third harmonic has cubic dependence on input voltage and decreases with an increase in frequency. The mechanism is discussed according to which generation of non-compensated second harmonic is due to the formation of the intermediate lipid phase with viscoelastic properties differing from the initial bilayer in the process of structural rearrangements. The presence of this phase conditions the possibility of appearance of noncompensated second harmonic.
mesh_terms: D004560:Electricity; D005990:Glycerol; D008051:Lipid Bilayers; D008564:Membrane Potentials; D008962:Models, Theoretical; D019946:Propylene Glycol; D011409:Propylene Glycols; D012996:Solutions
chemical_list: D008051:Lipid Bilayers; D011409:Propylene Glycols; D012996:Solutions; D019946:Propylene Glycol; D005990:Glycerol
vernacular_title: Osobennosti generatsii vysshikh garmonik transmembrannogo toka v lipidnykh bisloiakh, nakhodiashchikhsia v rastvorakh glitserina i 1,2-propandiola.