title: [Clinical pathology of chronic hyperplastic laryngitis. 1. The epithelial structure of the transitional zone of the larynx].
abstract: Premalignant changes of the epithelium are most likely to be first observed in the transitional zone between squamous and respiratory epithelium in the larynx. The characteristics of this region were assessed in 115 biopsies. Considerable variation was observed in the type of epithelial lining and its grade of differentiation. Two types of glandular structures were seen: small salivary glands and adenoid crypts. The latter have not previously been described in this area. Morphologically they resemble Brunn's cell nests in the urinary bladder. The epithelium of the transitional zone with its crypts and pseudocarcinomatous hyperplasia must be carefully distinguished from dysplasia.
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007822:Laryngeal Neoplasms / Q000473:pathology*; D007827:Laryngitis / Q000473:pathology*; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology*
vernacular_title: Beitrag zur klinischen Pathologie der chronischen hyperplastischen Laryngitis. 1. Mitteilung: Die epithelialen Strukturen der Ubergangszone des Larynx.