Thromboxane B2 production during erection.
The effect of erection on 6-keto-PGF1 alpha and thromboxane B2 in penile blood during electrically evoked erection was studied in the chacma baboon. 6-keto-PGF1 alpha remained at a low concentration, but thromboxane B2 showed a statistically significant rise 8-10 minutes after commencement of erection. Elevated thromboxane B2 during erection may potentiate platelet aggregation and may be one of the key events in the pathogenesis of ageing impotence.
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D000375:Aging; D000818:Animals; D007172:Erectile Dysfunction / Q000209:etiology; D008297:Male; D010215:Papio; D010410:Penile Erection; D010974:Platelet Aggregation; D013929:Thromboxane B2 / Q000097:blood*
D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha