Maternal endocrine extirpations do not abolish maternal coordination of the fetal circadian clock.
The maternal circadian system coordinates the timing of the fetal circadian clock to the prevailing light-dark cycle. The role of various maternal endocrine organs as the source of a coordinating signal was investigated in rats. Either metabolic activity of the fetal suprachiasmatic nuclei or pineal N-acetyltransferase activity in 10-day-old pups was used to monitor the fetal circadian clock. Extirpations of the maternal pituitary, adrenals, thyroid-parathyroids, ovaries, or pineal (each performed in separate experiments) did not abolish maternal coordination.
D000123:Acetyltransferases / Q000378:metabolism; D000311:Adrenal Glands / Q000502:physiology; D000818:Animals; D002940:Circadian Rhythm; D004702:Endocrine Glands / Q000502:physiology*; D005260:Female; D005333:Fetus / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D008431:Maternal-Fetal Exchange; D010053:Ovary / Q000502:physiology; D010280:Parathyroid Glands / Q000502:physiology; D010870:Pineal Gland / Q000196:embryology / Q000502:physiology; D010902:Pituitary Gland / Q000502:physiology; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D013493:Suprachiasmatic Nucleus / Q000196:embryology / Q000378:metabolism; D013961:Thyroid Gland / Q000502:physiology
D000123:Acetyltransferases; D005947:Glucose