Hypoxanthine and adenine metabolism in bovine thyroid tissue.
Hypoxanthine was converted primarily to uric acid by thyroid tissue slices and homogenates with little inosine 5'-monophosphate formation while adenine was essentially all salvaged to adenosine 5'-monophosphate by similar tissue preparations. The ratio of hypoxanthine/guanine phosphoribosyltransferase activity to adenine phosphoribosyltransferase activity was 0.15 in the thyroid homogenates.
D000225:Adenine / Q000378:metabolism*; D000228:Adenine Phosphoribosyltransferase / Q000378:metabolism; D000818:Animals; D002417:Cattle; D019271:Hypoxanthine; D007041:Hypoxanthine Phosphoribosyltransferase / Q000378:metabolism; D007042:Hypoxanthines / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D013055:Spectrophotometry, Infrared; D013961:Thyroid Gland / Q000201:enzymology / Q000378:metabolism*; D014969:Xanthine Oxidase / Q000378:metabolism
D007042:Hypoxanthines; D019271:Hypoxanthine; D014969:Xanthine Oxidase; D000228:Adenine Phosphoribosyltransferase; D007041:Hypoxanthine Phosphoribosyltransferase; D000225:Adenine