[Effect of a leukocytic serum preparation on hematopoietic cells in vitro].
The effects of leucocyte serum (LS) on bone marrow cells (BMC), thymus and HL-60 human myeloid leukemia cells were studied in liquid suspension and agar cultures. LS increased 3H-thymidine incorporation in BMC and intensified the cloning efficiency of granulocyte-macrophage progenitor cells (CFU-GM) and human myeloid leukemia cells. No significant stimulatory effect on thymus cells was observed. It has been shown that LS prevents or markedly decreases the effect of granulocyte inhibitor (GI-3S2).
D000818:Animals; D002455:Cell Division; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006736:Horses; D007962:Leukocytes / Q000502:physiology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
Vliianie preparata leĭkotsitarnoĭ syvorotki na krovetvornye kletki in vitro.