Identification of a putative second T-cell receptor.
Framework monoclonal antibodies have identified a population of human lymphocytes that express the T3 glycoprotein but not the T-cell receptor (TCR) alpha- and beta-subunits. Chemical crosslinking experiments reveal that these lymphocytes express novel T3-associated polypeptides, one of which appears to be the product of the T gamma gene. The other polypeptide may represent a fourth TCR subunit, designated T delta.
D000911:Antibodies, Monoclonal; D002460:Cell Line; D004247:DNA; D004586:Electrophoresis; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000276:immunology; D009693:Nucleic Acid Hybridization; D011948:Receptors, Antigen, T-Cell / Q000032:analysis*
D000911:Antibodies, Monoclonal; D011948:Receptors, Antigen, T-Cell; D004247:DNA