[Conservative treatment of tumors of the retina at the Curie Institute. 5-year ophthalmologic results of 129 cases treated with the Stallard disc and electrons].
The authors report a retrospective study of 129 children with retino-blastoma treated from 1963 to 1977 at the Institute Curie by enucleation of the worst eye and conservative irradiation of the other eye; this irradiation was performed either with Stallard plaque (19 cases) or with electrons (110 cases). In 8 familial cases no enucleation was performed. T.E.M. was used from 1964 to 1973 and iterative photocoagulation has been performed since 1968. Five years absolute NED survival rate was 68% (88/129 children). In these 88 children, 94 eyes were irradiated. Ophthalmological results were as follows: 21 eyes were enucleate secondarily (20/21 were tumoral); the attempt of ocular conservation was succeeded in 78% of the cases: 73 of the 94 irradiated eyes were cured; among these 73 cured eyes, 4 had complications and 15 had sequelae; the others 54 eyes were normal; only 5 eyes escaped ophthalmological survey; for the other 68 eyes vision was evaluated: 2 eyes (3%) were functional but vision could not be measured; 10 (14%) had less than 1/10 of visual acuity; 14 (19%) had vision at least equal to 1/10 but less than 5/10; 42 (57%) had 5/10 or more. 62% of all irradiated eyes (58/94) and 79% of conservated eyes (58/73) had "useful vision". Results are discussed and compared with these published by other teams; the authors try to determine elements of visual prognosis.
D000367:Age Factors; D002386:Cataract / Q000209:etiology; D002648:Child; D005134:Eye Neoplasms / Q000503:physiopathology / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D013508:Ophthalmologic Surgical Procedures; D011379:Prognosis; D012166:Retinal Hemorrhage / Q000175:diagnosis; D012175:Retinoblastoma / Q000503:physiopathology / Q000532:radiotherapy* / Q000601:surgery; D012189:Retrospective Studies; D014792:Visual Acuity
Traitement conservateur des tumeurs de la rétine à l'Institut Curie. Résultats ophtalmologiques à 5 ans de 129 cas traités par disque de Stallard et électrons.