title: Isolation of a human ceruloplasmin cDNA clone that includes the N-terminal leader sequence.
abstract: A number of cDNA clones encoding human ceruloplasmin were identified using two mixed oligonucleotide probes. One of these clones was shown by DNA sequence analysis to span from the complete N-terminal leader sequence to 114 amino acids short of the C-terminus. The leader sequence consists of 19 primarily hydrophobic amino acids. Northern blot analysis of RNA from human liver showed two species of ceruloplasmin mRNA; a minor species of 3600 nucleotides and a major one of 4400 nucleotides.
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002570:Ceruloplasmin / Q000032:analysis / Q000235:genetics*; D004247:DNA / Q000032:analysis*; D006801:Humans; D012333:RNA, Messenger / Q000032:analysis
chemical_list: D012333:RNA, Messenger; D004247:DNA; D002570:Ceruloplasmin