Parenteral benzyl alcohol-induced hypersensitivity reaction.
An uncommon hypersensitivity reaction due to parenteral benzyl alcohol administration is reported. One patient treated with benzyl alcohol-preserved cytarabine, vincristine, and heparin solutions developed a systemic hypersensitivity reaction on three separate occasions. Hypersensitivity to benzyl alcohol was confirmed by skin testing. Clinically, the patient presented with a fever and a maculopapular rash on the chest and arms. None of the reactions were life-threatening or required hospitalization of the patient.
D019905:Benzyl Alcohol; D001592:Benzyl Alcohols / Q000009:adverse effects*; D001593:Benzyl Compounds / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D019905:Benzyl Alcohol