Experimental calcium oxalate retinopathy compared with cystine- and tyrosine-induced retinal damage. An ophthalmoscopical, histological, and electrophysiological study.
Subcutaneously administered calcium chloride and dibutyloxalate solutions produce calcium-oxalate retinopathy in rabbits that is demonstrable opthalmoscopically and histologically, with remarkable impairment of the electroretinogram, whereas orally administered cystine seems to be inefficient. Orally administered tyrosine induces transitory pathological ERG signals in rabbits.
D000818:Animals; D002129:Calcium Oxalate / Q000494:pharmacology*; D003553:Cystine / Q000494:pharmacology*; D004596:Electroretinography; D008297:Male; D009887:Ophthalmoscopy; D011817:Rabbits; D012164:Retinal Diseases / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D014443:Tyrosine / Q000494:pharmacology*
D002129:Calcium Oxalate; D014443:Tyrosine; D003553:Cystine