title: Significance of urinary phenyl sulfate and phenyl glucuronide as indices of exposure to phenol.
abstract: Urine samples from subjects, who had been using phenol for treatment of chemical fiber in factories, were analysed for urinary phenyl sulfate (PhS) and phenyl glucuronide (PhG) by high-performance liquid chromatography (HPLC). The urinary levels of phenol metabolites (PhG and PhS) had a significant correlation with the environmental concentration of phenol. The urinary concentration of phenol metabolites, as a total of PhS and PhG, corresponding to 5 ppm of environmental phenol was 251 mg phenol/g creatinine.
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005965:Glucuronates / Q000652:urine*; D006801:Humans; D008657:Metabolic Clearance Rate; D009784:Occupational Diseases / Q000139:chemically induced*; D019800:Phenol; D010636:Phenols / Q000009:adverse effects*; D013463:Sulfuric Acid Esters / Q000652:urine*; D013464:Sulfuric Acids / Q000652:urine*
chemical_list: D005965:Glucuronates; D010636:Phenols; D013463:Sulfuric Acid Esters; D013464:Sulfuric Acids; C025298:phenylglucuronide; D019800:Phenol; C025208:phenylsulfate