A simple method for obtaining cerebrospinal fluid from a pig model of herpes encephalitis.
A procedure is described for obtaining cerebrospinal fluid (CSF) from anesthetized pigs by puncturing the cisterna magna. CSF samples of at least 5 ml. can be obtained. The punctures are well tolerated and can be repeated with intervals of approximately 4 days.
D000818:Animals; D002555:Cerebrospinal Fluid / Q000032:analysis*; D002946:Cisterna Magna; D004195:Disease Models, Animal; D004660:Encephalitis / Q000134:cerebrospinal fluid*; D006561:Herpes Simplex / Q000134:cerebrospinal fluid*; D013048:Specimen Handling / Q000379:methods; D013552:Swine / Q000134:cerebrospinal fluid*