Chloramphenicol concentrations in calf muscle tissue.
Twenty-five 9- to 11-week-old calves were administered 2 doses of chloramphenicol prepared in propylene glycol (13.6 mg/kg of body weight IV; 6.8 mg/kg IM; or 13.6 mg/kg IM) at 24-hour intervals. Calves were euthanatized at designated times from 2 to 72 hours after the last dose was administered. Muscle tissues were collected immediately after euthanasia, and chloramphenicol concentrations in the tissues were determined.
D000818:Animals; D002417:Cattle / Q000378:metabolism*; D002701:Chloramphenicol / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism*; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007700:Kinetics; D009132:Muscles / Q000032:analysis / Q000378:metabolism*
D002701:Chloramphenicol