Electrophysiological assessment of monoamine synaptic function in neuronal circuits of seizure susceptible brains.
The following report reviews evidence suggesting a role for the monoamines, norepinephrine (NE) and serotonin (5-HT), in the pathophysiology of seizure disorders and outlines a strategy for electrophysiologically evaluating monoaminergic function at the synaptic level in central neuronal circuits of two animal models of epilepsy.
D000588:Amines / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000166:cytology* / Q000502:physiology; D004195:Disease Models, Animal; D004558:Electric Stimulation; D004594:Electrophysiology; D004827:Epilepsy / Q000235:genetics / Q000503:physiopathology*; D009474:Neurons / Q000502:physiology; D009638:Norepinephrine / Q000502:physiology; D011689:Purkinje Cells / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000502:physiology; D013569:Synapses / Q000502:physiology*
D000588:Amines; D012701:Serotonin; D009638:Norepinephrine