title: [Fetal bigeminus following combined bronchodilator treatment of the mother].
abstract: After a combined bronchodilatory treatment of theophylline and terbutaline an intermittant fetal bigeminus is observed. The cardiotoxic changes disappear after days when treatment is stopped. After delivery the child is healthy. The slow disappearance of the arrhythmia is a result of the prolonged half-life of theophylline in the fetus. A combined therapy for asthma should be avoided. If this is not possible, regular cardiologic controls of the fetus should be carried out.
mesh_terms: D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D001249:Asthma / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced*; D006340:Heart Rate, Fetal / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D013726:Terbutaline / Q000009:adverse effects* / Q000627:therapeutic use; D013806:Theophylline / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D013806:Theophylline; D013726:Terbutaline
vernacular_title: Fetaler Bigeminus nach kombinierter bronchodilatatorischer Behandlung der Mutter.