Colchicine prophylaxis in pseudogout.
Ten patients with recurrent attacks of pseudogout were followed for 1 year before and 1 year after receiving oral colchicine 0.6 mg BID. Thirty-two episodes of acute arthritis were recorded in the year (3.2/patient/year) before the start of the drug and only 10 while taking the drug (1/patient/year) (p less than 0.001). Ninety percent of the patients benefitted from the drug. Our study supports the effectiveness of oral colchicine as a prophylactic agent in recurring pseudogout.
D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D001168:Arthritis / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D002805:Chondrocalcinosis / Q000150:complications / Q000188:drug therapy / Q000517:prevention & control*; D003078:Colchicine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence
D003078:Colchicine