Percutaneous bone biopsy in the patient with known or suspected osseous metastases.
One hundred fifty-three percutaneous bone biopsies were performed on 70 patients with and 83 patients without a known extraosseous primary tumor who had either scintigraphic evidence or plain radiographic evidence suggesting bony metastases. Biopsy results were shown to be true-negative, true-positive, or false-negative based on results of the needle biopsy, open biopsy, or radiographic follow-up. The overall accuracy of biopsy was 95.4%. In the group with positive scans only, the accuracy was 85.7%. Twenty-nine percent of the patients with known cancer and 33.7% of patients without cancer proved to have benign causes for their radiographic abnormality. The rate of significant complications was 0.7%. Biopsy of suspect osseous lesions can be performed safely and may significantly alter treatment. Biopsy of scan-positive, radiograph-negative lesions is a highly accurate procedure.
D001706:Biopsy; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000556:secondary; D001943:Breast Neoplasms / Q000473:pathology; D002277:Carcinoma / Q000473:pathology* / Q000556:secondary; D005188:False Negative Reactions; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000473:pathology / Q000556:secondary; D014057:Tomography, X-Ray Computed