[HPLC detection of pathologic metabolites of melanin and melatonin metabolism in the urine in malignant melanoma of the choroid].
In 19 patients with malignant melanoma of the choroid and 11 controls 20 different metabolic parameters of melanin and melatonin metabolism in urine were examined by high-pressure liquid chromatography (HPLC). Significant differences were found in DOPA, DOPAC, MHPG, alpha-keto-glutaric acid, pseudo-uridine, serotonin, OH-tryptophan and homovanillic acid.
D002830:Choroid Neoplasms / Q000652:urine*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D008543:Melanins / Q000652:urine*; D008545:Melanoma / Q000652:urine*; D008550:Melatonin / Q000652:urine*
D008543:Melanins; D008550:Melatonin
HPLC-Nachweis pathologischer Metaboliten des Melanin- und Melatoninstoffwechsels im Urin bei malignem Melanom der Aderhaut.