Cerebellar aspergilloma.
A cerebellar aspergilloma simulating brain tumour in a 48-year-old woman with alveolar proteinosis is described. The course of the disease was recurrent. Despite neurosurgery, ventricular drainage, amphotericin B, flucytosine and other antifungal agents, the disease was ultimately fatal. The diagnostic and therapeutic problems of aspergillosis in the central nervous system are discussed. Suspicion and serology might lead to early diagnosis and a better prognosis.
D001228:Aspergillosis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis; D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D012008:Recurrence