Splanchnic hemodynamic changes after the distal spleno renal shunt.
Marked changes in preoperative to postoperative corrected sinusoidal pressures (CSP) occurred in 51 per cent of a series of 51 patients undergoing the distal splenorenal shunt. Twenty patients who had the highest incidence of partial portal vein thrombosis, (48%--Group I), showed minimal pre- to postoperative changes in CSP. Twelve patients (Group II) who increased their CSP to 4 mm Hg or greater had marked postoperative hyperbilirubinemia and decreased portal blood flow. Fourteen patients who decreased their CSP 4 mm Hg or more postoperatively also showed moderate portal blood flow decrease without significant changes in liver enzymes. Morbidity and mortality were not significantly different among the three groups. The significance of these hemodynamic changes is not known.
D000328:Adult; D001794:Blood Pressure; D006439:Hemodynamics; D006801:Humans; D007902:Length of Stay; D008102:Liver Circulation; D008103:Liver Cirrhosis / Q000601:surgery; D008104:Liver Cirrhosis, Alcoholic / Q000601:surgery; D008875:Middle Aged; D011170:Portasystemic Shunt, Surgical; D013164:Splenorenal Shunt, Surgical; D014690:Venous Pressure