title: Thermostabilization of Inoue-Melnick virus by salt.
abstract: Inoue-Melnick virus (IMV) was stabilized to thermal inactivation at 50 degrees C by 1 M Na2SO4 but not by 1 M MgCl2, 1 M MgSO4, 2 M NaCl, and 2 M KCl. The latter salts enhanced the inactivation over that in distilled water. Na2SO4 stabilized IMV at 1 M concentration but enhanced inactivation at 0.1 M. Three types of IMV were stabilized by 1 M Na2SO4 at 50 degrees C to almost the same degree. The pattern of the thermostabilization of IMV by salts was similar to that of herpes simplex virus; however, the degree of its stabilization was lower with prolonged heating.
mesh_terms: D006564:Herpesviridae / Q000187:drug effects / Q000502:physiology*; D006358:Hot Temperature; D007700:Kinetics; D009994:Osmolar Concentration; D012492:Salts; D013431:Sulfates / Q000494:pharmacology; D014776:Virus Cultivation / Q000379:methods
chemical_list: D012492:Salts; D013431:Sulfates; C012036:sodium sulfate