title: [Pathological anatomy of herpetic brain lesions in infants].
abstract: Results of morphological examination of brain herpetic lesions in 29 children are presented. There were 5 observations of necrotic meningo-encephalitis, among children with generalized intrauterine herpes, less severe changes were found in other cases. 14 children suffered from acute necrotic meningo-encephalitis developed after birth. Changes typical for herpes are described in neural, glial and ependymal cells; the type of response in different forms of lesions is shown. The correlation between the gangliosides content in the brain tissue and the surviving neural cells and a specific increase of ganglioside GD1b fraction in brain tissue were demonstrated by biochemical and morphological studies.
mesh_terms: D000208:Acute Disease; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000151:congenital / Q000473:pathology*; D005260:Female; D005315:Fetal Diseases / Q000473:pathology; D006561:Herpes Simplex / Q000151:congenital / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D008590:Meningoencephalitis / Q000151:congenital / Q000473:pathology; D009336:Necrosis; D011247:Pregnancy
vernacular_title: Patologicheskaia anatomiia gerpeticheskikh porazheniĭ golovnogo mozga u deteĭ.