[Choice of antidepressive agents as a function of membrane transport (erythrocytes) of monoamine precursors (L-tyrosine and L-tryptophan)].
In a group of 66 depressed patients, the choice of the antidepressant drug was based upon the result of tyrosine and tryptophan uptake by the membrane of red blood cells. After one month of treatment, 56 subjects were improved, that is 85% of the cases. This result is discussed in comparison with the percentage of improvement described in the literature.
D000928:Antidepressive Agents / Q000627:therapeutic use*; D001692:Biological Transport; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy*; D003937:Diagnosis, Differential; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006801:Humans; D014364:Tryptophan / Q000097:blood*; D014443:Tyrosine / Q000097:blood*
D000928:Antidepressive Agents; D014443:Tyrosine; D014364:Tryptophan
Choix des antidépresseurs en fonction du transport membranaire (érythrocytes) des précurseurs des monoamines (L-tyrosine et L-tryptophane).