[Tumor-associated mononuclear cell infiltrate and recurrence rate in the superficial urothelial carcinoma of the urinary bladder].
Investigation on the absence or presence of malignancy-associated mononuclear cell infiltration in correlation to the recurrence rate after topic adriamycin chemotherapy was made in 53 patients with a superficial urothelial carcinoma of the urinary bladder after transurethral resection. The tumor recurrence rate, after an average observation period of 2.8 years, was 55%. Malignancy-associated mononuclear cell infiltration was found in 18 cases (34%) and of these, 6 (33%) showed recurrence. Absence of cell infiltration was found in 35 cases (66%) and of these, 23 (66%) showed recurrence. In those tumors which showed recurrence, cell infiltration was absent in 83%, whereas it was absent in only 46% of the tumors without recurrence.
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006644:Histiocytes / Q000276:immunology / Q000502:physiology; D006651:Histocytochemistry; D006801:Humans; D008214:Lymphocytes / Q000276:immunology / Q000502:physiology*; D008297:Male; D008407:Mast Cells / Q000502:physiology; D011379:Prognosis; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*
D004317:Doxorubicin
Tumorassoziiertes mononukleäres Zellinfiltrat und Rezidivneigung beim oberflächlichen Urothelkarzinom der Harnblase.