Simple catheter preparation for permitting bolus intrathecal administration during chronic intrathecal infusion.
This paper briefly describes a simple method for preparing a polyethylene "Y" catheter in which the stem of the "Y" is inserted into the intrathecal space, one arm of the "Y" is externalized for intrathecal injection and the other arm of the "Y" connected to an osmotic infusion pump. This simple preparation permits the chronic infusion of drug into the spinal space and without further surgical preparation, permits bolus injection of drugs through the same catheter.
D000818:Animals; D002404:Catheterization / Q000379:methods*; D002408:Catheters, Indwelling; D007278:Injections, Spinal / Q000379:methods*; D008297:Male; D009480:Neuropharmacology / Q000379:methods*; D051381:Rats; D011919:Rats, Inbred Strains; D013346:Subarachnoid Space