Fatality resulting from methylphenidate overdose.
A case involving an accidental overdose fatality resulting from an intravenous injection of crushed Ritalin (methylphenidate) tablets is presented. The drug was quantified by gas chromatography/nitrogen-phosphorus detection and confirmed by gas chromatography/mass spectrometry. Concentrations of drug were as follows: blood, 2.8 mg/L; bile, 5.7 mg/L; kidney, 3.0 mg/kg; liver, 2.1 mg/kg; and stomach contents, 1.6 mg total. Other drugs and volatile substances were not detected.
D000328:Adult; D002849:Chromatography, Gas; D005260:Female; D006801:Humans; D007202:Indicators and Reagents; D008774:Methylphenidate / Q000032:analysis / Q000097:blood / Q000506:poisoning*
D007202:Indicators and Reagents; D008774:Methylphenidate