[Corrective effect of trimethylglycine on the nicotinamide coenzyme and adenine nucleotide content of the tissues in experimental atherosclerosis].
Experiments on adult rabbits with experimental atherosclerosis induced by cholesterol (0.25 g/kg for 90 days) showed that chronic administration of trimethylglycine (1.5 g/kg for 30 days) prevented a decrease of the liver and myocardium content of nicotinamide coenzymes and adenine nucleotides.
D000227:Adenine Nucleotides / Q000378:metabolism*; D000818:Animals; D001161:Arteriosclerosis / Q000188:drug therapy* / Q000378:metabolism; D001622:Betaine / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D004734:Energy Metabolism / Q000187:drug effects; D006321:Heart / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D009243:NAD / Q000378:metabolism*; D009249:NADP / Q000378:metabolism*; D010084:Oxidation-Reduction / Q000187:drug effects; D011817:Rabbits
D000227:Adenine Nucleotides; D009243:NAD; D001622:Betaine; D009249:NADP
Korrigiruiushchee vliianie trimetilglitsina na soderzhanie nikotinamidnykh kofermentov i adeninnukleotidov v tkaniakh pri éksperimental'nom ateroskleroze.