Cloning of rabies virus matrix protein mRNA and determination of its amino acid sequence.
A cDNA clone of mRNA for rabies virus matrix (M) protein has been identified. The clone hybridizes to an mRNA species from rabies virus-infected cells, whose size correlates to the size of the M protein in rabies virions, and selects an mRNA that translates into a polypeptide corresponding in size to M protein. The nucleotide sequence of the cloned cDNA was determined and from this a complete amino acid sequence for M protein was deduced. The deduced sequence of 202 amino acids bears no detectable sequence homology with vesicular stomatitis virus M protein although these proteins may share functional homology.
D000595:Amino Acid Sequence; D001483:Base Sequence; D002460:Cell Line; D003001:Cloning, Molecular; D004247:DNA / Q000378:metabolism*; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000235:genetics*; D011820:Rabies virus / Q000235:genetics*; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000235:genetics*
D012333:RNA, Messenger; D014763:Viral Matrix Proteins; D014764:Viral Proteins; D004247:DNA