[Chromosome aberrations and reproductive death of mammalian cells. Quantitative relations between these effects].
The data reported in the literature concerning the relationship between the yield of chromosome aberrations and the number of cells without aberrations, on the one hand, and the survival rate of mammalian cells, on the other, with a reference to different types of radiation are reviewed in this article. It is shown that the number of chromosome aberrations per one lethal damage, as to the results obtained by different authors, ranges from 0.5 to 1.5, this discrepancy is mainly due to different methods applied by different authors, and at least one chromosome aberration corresponds to a lethal damage caused by irradiation in the G1 phase.
D000818:Animals; D002453:Cell Cycle / Q000528:radiation effects; D002460:Cell Line; D002470:Cell Survival / Q000528:radiation effects*; D002869:Chromosome Aberrations / Q000528:radiation effects*; D006224:Cricetinae; D003412:Cricetulus; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008954:Models, Biological; D051381:Rats
Khromosomnye aberratsii i reproduktivnaia gibel' kletok mlekopitaiushchikh. Kolichestvennye sootnosheniia mezhdu étimi éffektami.