Remarkable responses of metastatic renal cell cancer in multiple organs treated with alpha-interferon.
We report a case of renal cell carcinoma with metastases in the lungs, humerus and brain, which we treated with alpha-interferon. After a transperitoneal nephrectomy the patient received a series of intramuscular injections of alpha-interferon every 2 days. Two months after the initial therapy complaints of pain in the humeral bone gradually decreased and the palpable mass in the right brachial region disappeared completely. A computerized tomography scan revealed only the scar of the intracranial metastasis. Most of the pulmonary lesions disappeared 4 months later except for the metastasis at the apex of the left lung.
D000328:Adult; D001859:Bone Neoplasms / Q000556:secondary / Q000628:therapy; D001932:Brain Neoplasms / Q000556:secondary / Q000628:therapy; D002292:Carcinoma, Renal Cell / Q000556:secondary* / Q000628:therapy; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D007680:Kidney Neoplasms / Q000628:therapy*; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy; D008297:Male; D009392:Nephrectomy; D011994:Recombinant Proteins / Q000627:therapeutic use*
D007370:Interferon Type I; D011994:Recombinant Proteins