Methods for improvement of the success rate of artificial insemination with donor semen.
The cumulative probability of conception within 12 cycles of insemination with frozen-thawed donor semen increased from 59 to 70% by selecting the semen on the basis of its concentration of adenosine triphosphate (ATP) rather than on the basis of its motile sperm count. The success rate further improved to 83% by performing induction of ovulation in all recipients who did not achieve pregnancy within the initial 6 cycles.
D000206:Actuarial Analysis; D000255:Adenosine Triphosphate / Q000032:analysis; D005260:Female; D005306:Fertilization; D005615:Freezing; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D007316:Insemination, Artificial, Heterologous / Q000379:methods*; D008297:Male; D011247:Pregnancy; D011336:Probability; D012661:Semen / Q000032:analysis; D012662:Semen Preservation
D000255:Adenosine Triphosphate