Catecholaminergic binding sites in cat retina, pigment epithelium and choroid.
The distribution of catecholaminergic binding sites was studied in the cat eye by measuring binding of [3H]spiperone and [3H]dihydroalprenolol in central and peripheral parts of the neural retina, in retinal pigment epithelium, and in choroid homogenates. Significant binding to beta-adrenergic sites was present in central and peripheral neural retina and choroid homogenates, whereas significant binding to dopaminergic D2 sites was found in homogenates of neural retina and retinal pigment epithelium.
D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D001665:Binding Sites; D002395:Catecholamines / Q000378:metabolism*; D002415:Cats; D002829:Choroid / Q000378:metabolism*; D004082:Dihydroalprenolol / Q000378:metabolism; D010857:Pigment Epithelium of Eye / Q000378:metabolism*; D012160:Retina / Q000378:metabolism*; D013134:Spiperone / Q000378:metabolism
D002395:Catecholamines; D013134:Spiperone; D004082:Dihydroalprenolol; D001205:Ascorbic Acid