Familial Bartter's syndrome: report of a case with early manifestations and persistent hypercalciuria.
A case of familial Bartter's syndrome is reported. The child had early and severe clinical and biochemical manifestations. Indomethacin treatment effectively controlled the increased prostaglandin excretion but corrected only partially the potassium and the calcium losses. The child developed during treatment high serum calcium levels which were associated with high parathyroid hormone and calcitriol serum levels.
D001477:Bartter Syndrome / Q000235:genetics* / Q000473:pathology / Q000652:urine; D002117:Calcitriol / Q000097:blood; D002118:Calcium / Q000652:urine*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000235:genetics*; D007213:Indomethacin / Q000627:therapeutic use; D007606:Juxtaglomerular Apparatus / Q000473:pathology; D010281:Parathyroid Hormone / Q000097:blood; D011453:Prostaglandins / Q000652:urine
D010281:Parathyroid Hormone; D011453:Prostaglandins; D002117:Calcitriol; D002118:Calcium; D007213:Indomethacin