[Prospective placebo-controlled double-blind study using a bacterial lysate in infections of the respiratory tract and ENT region in children].
94 children suffering from frequent infections of the respiratory tract and of the ear, nose and throat were treated under double-blind conditions with either a bacterial lysate (n = 45) or a placebo (n = 49). During the 6 months of the trial both treatments brought about a significant decrease in the incidence and duration of these infections as well as in the duration of concomitant antibiotherapy in comparison to the corresponding prior 6-month reference period. As these positive results recorded under the bacterial lysate and the placebo could not be differentiated statistically, the influence of meteorological and epidemiological factors as well as of the age of the children is discussed.
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D001419:Bacteria; D002457:Cell Extracts; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D004341:Drug Evaluation; D006801:Humans; D007223:Infant; D010038:Otorhinolaryngologic Diseases / Q000517:prevention & control*; D011446:Prospective Studies; D011897:Random Allocation; D012141:Respiratory Tract Infections / Q000517:prevention & control*; D000095983:Bacterial Lysates
D000276:Adjuvants, Immunologic; D002457:Cell Extracts; C030259:Broncho-Vaxom; D000095983:Bacterial Lysates
Prospektive placebo-kontrollierte Doppelblindstudie mit einem Bakterienlysat bei Infektionen der Atemwege und des ORL-Bereiches im Kindesalter.