Lymphangioma circumscriptum following mastectomy and radiation therapy.
We describe a woman who developed clear, tense vesicles in an area of chronic lymphedema 8 years following mastectomy and radiation therapy. The vesicles showed the clinical and pathologic features of lymphangioma circumscriptum, which can develop as a late sequelae of the lymphatic damage inherent in some forms of cancer therapy.
D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D008200:Lymphangiectasis / Q000209:etiology* / Q000473:pathology; D008208:Lymphatic System / Q000473:pathology; D008209:Lymphedema / Q000150:complications; D008408:Mastectomy / Q000009:adverse effects*; D008875:Middle Aged; D011183:Postoperative Complications; D011878:Radiotherapy / Q000009:adverse effects*