title: A comparison of the effects of some phenethylamines on the release of radioactivity from isolated rat caudate nucleus prelabelled with 3H-dopamine.
abstract: In order to evaluate a series of phenethylamines with regard to their capacity to induce release from presynaptic catecholamine stores, their effect on the efflux of radioactivity from 3H-dopamine-prelabelled rat caudate nucleus tissue was determined. All of the phenethylamines studied were found to enhance the release of radioactivity from this preparation. However, marked differences were observed between the individual compounds with regard to potency and dose dependence of the effect.
mesh_terms: D000818:Animals; D002421:Caudate Nucleus / Q000187:drug effects / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D003342:Corpus Striatum / Q000187:drug effects / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism*; D066298:In Vitro Techniques; D010627:Phenethylamines / Q000494:pharmacology*; D051381:Rats
chemical_list: D010627:Phenethylamines; D004298:Dopamine