Inhibition of cholera toxin production by thiols in Vibrio cholerae.
We found that thiols reduced the amount of cholera toxin produced by Vibrio cholerae 569B in vitro. A sulfhydryl group at least was necessary for the reduction of cholera toxin production by thiols.
D002772:Cholera Toxin / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D013438:Sulfhydryl Compounds / Q000494:pharmacology*; D014734:Vibrio cholerae / Q000187:drug effects / Q000378:metabolism*; D014805:Vitamin B 12 / Q000494:pharmacology
D013438:Sulfhydryl Compounds; D002772:Cholera Toxin; D014805:Vitamin B 12