Stimulating effect of unfractionated heparin and a low molecular weight heparin fragment on the DNA synthesis response of human thymocytes to mercuric chloride.
The effect of unfractionated heparin and a low molecular weight heparin fragment was tested on the DNA synthesis response of human thymocytes to mercuric chloride. In a concentration of 0.01-0.11 mg/ml, unfractionated heparin somewhat stimulated this response, while the heparin fragment at 11.1 mg/ml gave an evident stimulation of the response and a lower stimulation degree at 1.1 mg/ml.
D002478:Cells, Cultured; D006493:Heparin / Q000494:pharmacology*; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D008627:Mercuric Chloride / Q000494:pharmacology*; D008970:Molecular Weight; D013329:Structure-Activity Relationship; D013950:Thymus Gland / Q000166:cytology
D008627:Mercuric Chloride; D006493:Heparin