title: [Time course of NMR images and T1 values associated with hypertensive intracerebral hematoma].
abstract: The present study describes time courses in tissue T1 values, as well as in NMR imagings, associated with hypertensive intracerebral hematoma (ICH). Non-operative 21 cases of ICH were examined by FONAR QED 80-alpha NMR system, which possessed dual modes of image display and focal T1 measurement (static magnetic field: 433 gauss). As the first step of examination SSFP images are displayed and then, at the regions of interest, absolute values of T1 are measured by field focusing technique. The extent of ICH was revealed as high density zone in NMR imaging, occasionally represented much wider extent of high density area than the finding on X-ray CT. Prolonged T1 values were obtained from such high density zone. This wide-spread high density area was regarded to reflect the spread of perifocal brain edema. T1 value of the hematoma itself was rather shortened in its initial phase within 2 weeks, thereafter followed by prolongation in the time lapse. This seemed to reflect the alterations in the properties of hematoma such as clot formation in earlier phase and resolution in later phase. On the contrary, T1 in the brain tissue surrounded to hematoma was apparently prolonged in the early phase within 2 weeks, representing the maximal values of 312 msec around 2 to 4 weeks after the onset, and then gradually normalized in the period over 1 month. This alteration in tissue T1 likely represents the processes of edema formation and its regression in perifocal zone. T1 values measured in perifocal region might be available for the evaluation of edema state in association with cerebrovascular accident.
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000175:diagnosis*; D005260:Female; D006406:Hematoma / Q000175:diagnosis*; D006801:Humans; D006973:Hypertension / Q000150:complications*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014057:Tomography, X-Ray Computed