title: The effects of stimulant drugs on information processing in elderly adults.
abstract: The effects of stimulant drug on information processing in elderly adults was studied. In Experiment 1, the effect of methylphenidate (MP) was examined in 8 young and 8 elderly women using a task (SERS) in which stimulus and response complexities were varied. MP speeded processing in the young but not in the elderly women. A second experiment was then conducted to isolate the age-stimulant effects. In Experiment 2, the effects of MP and 10 mg of d-amphetamine (DAMP) were studied in 12 young and 12 elderly men on different types of information processing. Stimulants changed performance on a continuous performance task in both groups. Both stimulants speeded processing on SERS in young, but not in elderly men. MP, however, speeded processing in both groups on a response processing task. The findings suggest that stimulants act on response processing and there appear to be several such processes. Some of these stages decline with age whereas others do not.
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D003071:Cognition / Q000187:drug effects*; D003913:Dextroamphetamine / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007360:Intelligence; D008297:Male; D008774:Methylphenidate / Q000494:pharmacology*; D008875:Middle Aged; D011597:Psychomotor Performance / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects; D012737:Sex Factors
chemical_list: D008774:Methylphenidate; D003913:Dextroamphetamine