Cystic fibrosis presenting in a 45-year-old man with infertility.
Cystic fibrosis commonly is regarded as a disease of childhood associated with severe pulmonary and pancreatic pathological conditions. We report on a previously healthy 45-year-old man who was diagnosed as having cystic fibrosis after presentation with primary azoospermia. The literature is reviewed. Although references are made to late presentations of cystic fibrosis none was found in which the initial complaint was infertility. Primary azoospermia may be the presenting manifestation of cystic fibrosis in the absence of major respiratory symptoms.
D003550:Cystic Fibrosis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009845:Oligospermia / Q000209:etiology*