[Kidney function and the effectiveness of hypotensive therapy of patients with hypertension].
Ischemic renal lesion in 108 patients with hypertension was diagnosed by means of the determination of slow isoenzymes of carbonic esterases (CE5-7) in the urine. Their detection was a poor prognostic sign for any therapeutic method, particularly with the use of propranolol deteriorating renal circulation. The use of drugs not deteriorating or improving the renal blood flow (dopegyt, chlophelin, reserpine, apressin, corinfar, isoptin) brought about more promising results in such cases.
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002265:Carboxylic Ester Hydrolases / Q000652:urine; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D007527:Isoenzymes / Q000652:urine; D007668:Kidney / Q000187:drug effects / Q000503:physiopathology*; D008297:Male; D011379:Prognosis
D000959:Antihypertensive Agents; D007527:Isoenzymes; D002265:Carboxylic Ester Hydrolases
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