'In vitro' metabolism of N-picolyl-3,5-dimethylbenzamides.
'In vitro' metabolism of three isomeric N-picolyl-3,5-dimethylbenzamides was studied. The metabolites were isolated through TLC and HPLC techniques and identified by direct comparison with authentic compounds. The results of phenobarbital and 3-methyl-cholantrene inductions are given.
D000818:Animals; D001549:Benzamides / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
D001549:Benzamides; C050743:N-(2-picolyl)-3,5-dimethylbenzamide; C050744:N-(3-picolyl)-3,5-dimethylbenzamide; D008748:Methylcholanthrene; C016938:picobenzide; D010634:Phenobarbital