title: [Tendency toward bleeding in Noonan syndrome].
abstract: Bleeding tendency in Noonan-patients is only sporadically mentioned in literature. There is no equivocal opinion about its cause. By means of a questionnaire data were collected from 29 Noonan-patients, registered in our hospital. In about half of these patients these data indicated the existence of a bleeding tendency. Some of these patients revealed a marked thrombocytopathy characterised as a disturbance in secondary aggregation. Further research into the cause is desirable.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006101:Granuloma, Giant Cell / Q000601:surgery; D006470:Hemorrhage / Q000628:therapy; D006474:Hemorrhagic Disorders / Q000097:blood / Q000150:complications*; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000601:surgery; D009634:Noonan Syndrome / Q000150:complications*; D010974:Platelet Aggregation; D010979:Platelet Function Tests; D011183:Postoperative Complications / Q000628:therapy
vernacular_title: Bloedingsneiging bij het Noonan-syndroom.