title: Effect of swine lymphocyte antigen haplotypes on birth and weaning weights in pigs.
abstract: Birth weights of 708 live piglets and weaning weights of 566 piglets were used to investigate the effect of the swine lymphocyte antigen (SLA) complex on these traits in Large White pigs. Piglets were from litters of a long-term selection experiment to measure response for selection to increase litter size. SLA haplotypes were determined using conventional class I antisera. A total of 14 haplotypes were detected. The effect of SLA haplotype on birth and weaning weights was investigated using a statistical model that included the effects of experimental group, sire, dam, sex and SLA haplotype. Results indicated that SLA class I haplotype 13.1.3 increased birth weights (P less than 0.10) and significantly increased weaning weights (P less than 0.01). This effect of haplotype 13.1.3 on weaning weight was 605 +/- 215 g (0.3 standard deviations). SLA class I homozygosity did not appear to affect birth and weaning weights. These results suggest that the SLA complex plays an important role in early growth in the pig and that further study of SLA effects on growth and reproduction are warranted.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000941:Antigens / Q000235:genetics*; D001835:Body Weight; D005787:Gene Frequency; D006239:Haplotypes; D008214:Lymphocytes / Q000276:immunology*; D013552:Swine / Q000276:immunology*; D014886:Weaning
chemical_list: D000941:Antigens