title: [Analysis of arterial microporous teflon prosthesis following surgical excision].
abstract: Twenty-one prosthetic explants were analysed after being surgically excised from 19 patients whose average age at implantation was 54.8 years. The arterial prosthesis was implanted 19 times for an advanced arteriopathy (stage III and stage IV) and twice for a stage II. The average time that the implants were in place was 14.8 months (with extremes of 19 days and 4 years). Surgical reintervention was caused by thrombosis (18 cases), infection (twice) and one case of degeneration of the prosthesis. The explanted prostheses displayed an irregular capsule, an uneven filling of the wall and a fibrous proliferation adhering to the internal surface. The role of the latter appeared essential to the prevention of the invasion of the prosthesis wall by fibrous tissues. The destruction of the structure of the microporous teflon is also prevented. Furthermore, this prosthesis seemed adversely affected when creased by flexion: the reduction in the caliber of the internal lumen caused thrombosis and a detachment of the external capsule. When such a material is implanted, everything must be done to prevent twisting or damaging the prostheses.
mesh_terms: D000368:Aged; D001158:Arteries / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009068:Movement; D011138:Polytetrafluoroethylene / Q000032:analysis*; D012086:Reoperation; D013329:Structure-Activity Relationship; D013927:Thrombosis / Q000209:etiology
chemical_list: D011138:Polytetrafluoroethylene
vernacular_title: Analyse de prothèses artérielles en téflon microporeux après exérèse chirurgicale.