title: Validation of a simple method of assessing cardiac preejection period: a potential index of sympathetic nervous system activity.
abstract: Traditional noninvasive assessment of sympathetic nervous system (SNS) activity in cardiovascular functioning has been confounded by concurrent parasympathetic influences. Analyses of specific intervals of the cardiac cycle have indicated that the systolic preejection period (PEP) may serve as a reliable index of SNS activity independent of parasympathetic inhibition. In the present study, PEP values derived from a technique employing peripheral pulse wave tracings were compared to values obtained from simultaneous impedance cardiograph recordings. Recordings were made on 15 male subjects who were instructed to rest quietly sitting in an upright position. Results indicated that values obtained from both methods were highly correlated and not significantly different when measurement adjustments on total systole were taken into account. These findings support the validity of the fingertip peripheral-pulse method in obtaining measures of systolic time intervals under resting conditions.
mesh_terms: D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000502:physiology*; D002302:Cardiac Output; D002307:Cardiography, Impedance; D004562:Electrocardiography; D006347:Heart Sounds; D006801:Humans; D008297:Male; D011674:Pulse; D013564:Sympathetic Nervous System / Q000502:physiology*