title: Pathological rupture of the spleen in transforming non-Hodgkin's lymphoma.
abstract: Two patients with an initial diagnosis of a poorly differentiated lymphocytic lymphoma suffered a pathological rupture of the spleen in association with the histological transformation of the disease to a large cell lymphoma and the development of a leukaemic phase. The value of computerized tomographic scanning of the upper abdomen in confirming the diagnosis of splenic rupture is demonstrated.
mesh_terms: D000368:Aged; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous; D013161:Splenic Rupture / Q000000981:diagnostic imaging / Q000209:etiology*; D014057:Tomography, X-Ray Computed