Cardiac amyloidosis involving the conduction system and the aortocoronary neuroreceptors. Clinicopathologic correlates.
In a patient with cardiac primary amyloidosis with conduction disturbances and dynamic cardiocirculatory disorders, the specialized system of the heart and the hitherto neglected cardiac nerve plexus and annexed aortocoronary glomera were studied histologically. Amyloid deposition in the conduction system and in the nerves and neuroreceptors seemed to correlate with the dysrhythmic manifestations, and, respectively, with some undue responses to vasodilator therapy. The possible hazards deriving from involvement of the aortocoronary glomera in patients with amyloidosis have been pointed out accordingly.
D000686:Amyloidosis / Q000473:pathology* / Q000503:physiopathology; D001145:Arrhythmias, Cardiac / Q000209:etiology; D009202:Cardiomyopathies / Q000473:pathology* / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000209:etiology; D006329:Heart Conduction System / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011984:Sensory Receptor Cells / Q000473:pathology*