title: [Changes in the intracellular glucose-6-phosphate dehydrogenase metabolism in the rat liver during thiamine deficiency].
abstract: Patterns of intracellular glucose-6-phosphate dehydrogenase turnover were studied in liver tissue of intact and thiamin-deficient rats using a new procedure for the enzyme purification. The alternations, found in the half-life period, in constant rates of synthesis and degradation of the key enzyme of the pentosephosphate pathway, correlated with a decrease of the glucose-6-phosphate dehydrogenase activity in vitamin B1 deficiency.
mesh_terms: D000818:Animals; D002850:Chromatography, Gel; D005954:Glucosephosphate Dehydrogenase / Q000302:isolation & purification / Q000378:metabolism*; D006207:Half-Life; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008297:Male; D051381:Rats; D013832:Thiamine Deficiency / Q000201:enzymology*
chemical_list: D005954:Glucosephosphate Dehydrogenase
vernacular_title: Izmeneniia vnutrikletochnogo krugooborota gliukozo-6-fosfatdegidrogenazy pecheni krys pri nedostatochnosti tiamina.