title: Reflex excitation and inhibition of the lower oesophageal sphincter induced by gastric distension in the cat.
abstract: Reflex responses of the lower oesophageal sphincter (l.o.s.) to distension of the stomach were studied by electromyographic and manometric techniques. Distension of the fundus and gastric antrum by inflation of a balloon elicited two types of reflex response of the l.o.s. Thus, whereas excitatory responses were recorded following slight distensions, larger distensions resulted in inhibitory responses. Splanchnic fibres and sympathetic fibres originating from the stellate ganglion, as well as vagal fibres served as the efferent pathways for the excitatory reflex response. The efferent pathways for the inhibitory response involved only vagal fibres.
mesh_terms: D000200:Action Potentials; D000818:Animals; D002415:Cats; D004106:Dilatation; D004943:Esophagogastric Junction / Q000294:innervation / Q000502:physiology*; D005728:Ganglia, Sympathetic / Q000502:physiology; D009433:Neural Inhibition; D011930:Reaction Time; D012018:Reflex / Q000502:physiology*; D013270:Stomach / Q000294:innervation / Q000502:physiology*; D014628:Vagotomy