The use of three esterase kits to measure plasma cholesterol concentration in the rat and three other species.
Three enzymatic methods for the determination of cholesterol and its esters were applied to plasma samples obtained from normocholesterolaemic rats, dogs, rabbits and man. A major difference was observed for rat plasma values, where the results obtained with a microbial esterase for the hydrolysis of cholesteryl esters were much lower than those obtained with mammalian esterases. This difference was greater for rats than for the other three species studied and is probably related to the plasma distribution of lipoproteins in the rat.
D000818:Animals; D002784:Cholesterol / Q000097:blood*; D004285:Dogs; D004950:Esterases; D006801:Humans; D009994:Osmolar Concentration; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D011933:Reagent Kits, Diagnostic
D011933:Reagent Kits, Diagnostic; D002784:Cholesterol; D004950:Esterases