title: [Tolerance of 3.5 percent plasma protein solution].
abstract: In a prospective study we found 112 patients out of 9549 who had been given 3.5% plasma protein solution during the preceding year but no other blood derivatives and who had not received any immunosuppressive treatment. 68 patients agreed to be tested for sensitisation to 3.5% plasma protein solution. An intracutaneous test was performed as screening test. Two patients had a false positive reaction, but one of them had urticaria factitia and therefore a positive reaction to NaCl 0.9%. The other patient showed circumscribed reddening in the early phase only, whereas later readings were negative. Neither the test of total IgE by Paper Radio Immuno Sorbent Test (PRIST) nor the test for specific IgE antibodies by Radio Allergo Sorbent Test (RAST) showed any positive results. According to these findings there was no sensitisation to 3.5% plasma protein solution.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001798:Blood Proteins / Q000008:administration & dosage* / Q000009:adverse effects / Q000276:immunology; D002648:Child; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D011852:Radioallergosorbent Test; D013514:Surgical Procedures, Operative
chemical_list: D001798:Blood Proteins; D007073:Immunoglobulin E
vernacular_title: Verträglichkeits- untersuchungen bei Plasma-Protein-Lösung 3.5%.