title: Comparative in vitro activity of ciprofloxacin and other antimicrobial agents against aminoglycoside-resistant gram-negative rods and microorganisms isolated from patients with bacteremia.
abstract: The comparative in vitro activity of ciprofloxacin, norfloxacin, aztreonam, cefotaxime, ceftazidime, mezlocillin, azlocillin, and tobramycin was evaluated against 188 isolates from bacteremic patients and 161 aminoglycoside-resistant gram-negative rods. Although some streptococcal (particularly enterococcal) blood isolates, Pseudomonas spp., and nonfermentative gram-negative rods were not inhibited by ciprofloxacin, it was nevertheless the most active compound tested against both microorganism groups.
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002939:Ciprofloxacin / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D006090:Gram-Negative Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D018805:Sepsis / Q000382:microbiology
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin