[Significance of various respiratory viruses in the development of chronic nonspecific bronchopulmonary processes].
Combined virological and bacteriological studies were carried out in 83 patients with chronic bronchopulmonary diseases. Viral antigens, predominantly respiratory syncytial virus antigen, were detected in 72% of the patients in bronchial material obtained by bronchoscopy. Examinations for antibody of IgM and IgG classes specific for different viruses revealed acute infection in 79% of the patients which coincided with exacerbation of the process due to concomitant ARVD. The other patients had chronic virus infection. The over-time studies confirmed long-term persistence of viruses in bronchial epithelium in 15 patients (in 9 respiratory syncytial, in 5 adenovirus, in 1 parainfluenza virus). Thus, the above results showed respiratory viruses not only to play a role in exacerbation of chronic bronchopulmonary diseases, but in a number of cases apparently to be the main cause of their development.
D000258:Adenovirus Infections, Human / Q000209:etiology / Q000276:immunology / Q000382:microbiology; D000260:Adenoviruses, Human / Q000276:immunology / Q000302:isolation & purification; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D001980:Bronchi / Q000276:immunology / Q000382:microbiology; D001982:Bronchial Diseases / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008171:Lung Diseases / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D012328:RNA Viruses / Q000276:immunology / Q000302:isolation & purification; D014777:Virus Diseases / Q000209:etiology* / Q000276:immunology / Q000382:microbiology
D000914:Antibodies, Viral; D000956:Antigens, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Znachenie razlichnykh respiratornykh virusov v razvitii khronicheskikh nespetsificheskikh bronkholegochnykh protsessov.