title: Anthelmintic efficacy of febantel combined with praziquantel against Ancylostoma tubaeforme, Toxocara cati, and Taenia taeniaeformis in cats.
abstract: Forty cats, each harboring 2 or 3 parasitic infections (Ancylostoma tubaeforme, Toxocara cati, and/or Taenia taeniaeformis), were used to titrate the anthelmintic efficacy of a paste containing 3.4% febantel and 0.34% praziquantel. The cats were allotted into 4 groups (10 cats/group). For 3 consecutive days, the cats were given febantel/praziquantel at 5/0.5 mg/kg/day, 10/1 mg/kg/day, 15/1.5 mg/kg/day, or a blank paste vehicle (control) at 0.29 g/kg of body weight. The recommended dosage of 10 mg of febantel and 1 mg of praziquantel/kg cleared greater than or equal to 98% of the 3 helminth species.
mesh_terms: D000724:Ancylostomiasis / Q000188:drug therapy / Q000662:veterinary; D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy* / Q000469:parasitology; D002415:Cats; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006146:Guanidines / Q000627:therapeutic use*; D006373:Helminthiasis / Q000188:drug therapy; D006374:Helminthiasis, Animal; D008297:Male; D011223:Praziquantel / Q000627:therapeutic use*; D013622:Taeniasis / Q000188:drug therapy / Q000662:veterinary; D014120:Toxocariasis / Q000188:drug therapy / Q000662:veterinary
chemical_list: D004338:Drug Combinations; D006146:Guanidines; C040536:febantel-praziquantel paste; D011223:Praziquantel