title: [Density and chemical solubility of cholesteric biliary calculi by cholelytic preparations of bile acids (CHENO-USO FALK) in vitro].
abstract: Solubility of concrements in the bile obtained during surgery was studied in vitro in the presence of a definite amount of bile acids (CDCA and UDCA). Experiments were performed with multiple cholesterol concrements obtained from 37 patients who underwent cholecystectomy. Depending on the appearance, size and density the concrements were grouped as concrements of the same size or generation, concrements of two sizes, and concrements of more than two sizes so that they could be divided into three generations. It was established that density of one-generation concrements resembling pearl granules was far greater as compared to that of the other varieties of cholesterol concrements. The solving action of UDCA appeared more potent than that of CDCA.
mesh_terms: D001647:Bile Acids and Salts / Q000494:pharmacology*; D002635:Chenodeoxycholic Acid / Q000494:pharmacology; D002769:Cholelithiasis / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008722:Methods; D012995:Solubility; D014580:Ursodeoxycholic Acid / Q000494:pharmacology
chemical_list: D001647:Bile Acids and Salts; D002635:Chenodeoxycholic Acid; D014580:Ursodeoxycholic Acid; D002784:Cholesterol
vernacular_title: O plotnosti i khimicheskoĭ rastvorimosti kholesterinovykh zhelchnykh kamneĭ kholeliticheskimi preparatmai zhelchnykh kislot (CHENO-URSO FALK) in vitro.