title: [Ethambutol pharmacokinetics in pulmonary tuberculosis patients].
abstract: Specific features of ethambutol pharmacokinetics were studied in 53 patients with first detected pulmonary tuberculosis. Pharmacokinetic parameters were interpreted by using an one-part model with absorption. Pharmacokinetic parameters Cmax, Me infinity were shown to be distributed according to a normal law of distribution of probabilities, Kel--according to a logarithmically normal law.
mesh_terms: D000328:Adult; D004977:Ethambutol / Q000032:analysis / Q000378:metabolism*; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D013053:Spectrophotometry / Q000379:methods; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000378:metabolism*
chemical_list: D004977:Ethambutol
vernacular_title: Farmakokinetika étambutola u bol'nykh tuberkulezom legkikh.