NMR relaxation and the structure of a synthetic DNA poly(dA-dT).poly(dA-dT).
1H-1H and 31P-1H nuclear Overhauser effects and 31P NMR spin-lattice relaxation times were measured for a synthetic DNA poly(dA-dT).poly(dA-dT) in a low-salt aqueous solution. The results have shown that all bases in the double helix are anti-orientated with respect to deoxyribose residues and that the sugar-phosphate backbone has an alternating architecture.
D001483:Base Sequence; D004247:DNA / Q000032:analysis*; D004277:DNA, Single-Stranded / Q000032:analysis; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D011067:Poly dA-dT / Q000032:analysis*; D011089:Polydeoxyribonucleotides / Q000032:analysis*; D014961:X-Ray Diffraction
D004277:DNA, Single-Stranded; D011089:Polydeoxyribonucleotides; D011067:Poly dA-dT; D004247:DNA