[Amplification of myc-specific sequences in human colonic cancer].
DNA samples obtained from tumors and adjacent mucosa of the large bowel of a patient with large bowel multiple neoplasia were examined after Southern. The procedure established amplification of v-myc oncogene-related DNA sequences in 1 out of 5 tumors tested. Restriction fragments of amplified myc-specific sequences and matching c-myc and N-myc loci of the human genome differed in size.
D000230:Adenocarcinoma / Q000235:genetics; D001483:Base Sequence; D003110:Colonic Neoplasms / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics*; D005784:Gene Amplification; D006801:Humans; D066298:In Vitro Techniques; D009378:Neoplasms, Multiple Primary / Q000235:genetics; D009857:Oncogenes
D004273:DNA, Neoplasm
Amplifikatsiia myc-spetsificheskikh posledovatel'nosteĭ v kartsinome tolstoĭ kishki cheloveka.