title: [Effect of methotrexate on 5-fluorouracil metabolism and clinical studies with methotrexate and 5-fluorouracil sequential therapy].
mesh_terms: D004334:Drug Administration Schedule; D004357:Drug Synergism; D005472:Fluorouracil / Q000008:administration & dosage / Q000378:metabolism*; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage / Q000494:pharmacology*; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D005472:Fluorouracil; D008727:Methotrexate