title: [Effect of a vitamin complex with mineral substances on blood coagulation in rats when administered by different methods and in experimental hypercoagulation].
abstract: Experiments conducted on white rats have evidenced that a single injection of a complex of vitamins with mineral substances ("Complivit") in doses similar to the therapeutic induces a short-term hupocoagulemia, which is reproduced during long-term administration. The animals tolerance to thromboplastin is significantly increased in the period of hypocoagulemia. It is suggested that the complex can produce a favourable effect in cases with hypercoagulemia.
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D001778:Blood Coagulation Disorders / Q000097:blood / Q000188:drug therapy*; D003864:Depression, Chemical; D004338:Drug Combinations / Q000008:administration & dosage / Q000494:pharmacology; D004353:Drug Evaluation, Preclinical; D008297:Male; D008903:Minerals / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors; D014815:Vitamins / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D004338:Drug Combinations; C050178:Komplivit; D008903:Minerals; D014815:Vitamins
vernacular_title: Vliianie kompleksa vitaminov s mineral'nymi veshchestvami na gemokoaguliatsiiu u krys pri raznykh sposobakh vvedeniia i éksperimental'noĭ giperkoagulemii.