title: Liposarcoma of the larynx. Case report and literature review.
abstract: Primary liposarcoma of the larynx is extremely rare. To our knowledge, only eight cases have been documented in the English literature. We report a ninth case in a 54-year-old man. The recurrent 2-cm tumor was well differentiated and was treated with a supraglottic laryngectomy with partial neck dissection followed by radiotherapy. There has not been a second recurrence in 16 months. The majority of liposarcomas arising in the larynx have been of a favorable histologic type (well differentiated or myxoid). The tumor tends to occur in a supraglottic location in men of 40 years or more, and multiple recurrences are typical. The primary mode of treatment is wide surgical excision, with or without postoperative radiation therapy.
mesh_terms: D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D008080:Liposarcoma / Q000145:classification / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery