title: [Evaluation of ventilation using 133Xe for improved nuclear medicine lung diagnosis].
abstract: In 101 patients a combined examination of ventilation with 133Xe and of perfusion with 99mTc-HAM was performed. By using the device 101 (Veenstra) the wash-in, equilibrium and wash-out could be evaluated in one examination, the total time needed for one patient was about 10 min. In suspected lung embolism the specificity could be increased to 100% whereas the sensitivity remained constant at 93%. In patients with central obstruction, specificity could be increased from 60% to 87% and sensitivity from 54% to 70%. In the diagnosis of lung embolism, the additional examination of ventilation should be used in any case, in the diagnosis of central obstruction it is recommended.
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D008173:Lung Diseases, Obstructive / Q000000981:diagnostic imaging; D008175:Lung Neoplasms / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D014692:Ventilation-Perfusion Ratio; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes
vernacular_title: Ventilationsprüfung mit 133Xe zur weiterführenden nuklearmedizinischen Lungendiagnostik.