Identified vertebrate neurons that differ in axonal projection develop together.
The development of identified reticulospinal neurons of the zebrafish (Brachydanio rerio) was studied in order to learn if cell specific differences in axonal projection are correlated with cell specific differences in time of neuronal development. We examined the development of individually known reticulospinal neurons that are located in close proximity in the hindbrain but that project axons to targets on opposite sides of the spinal cord. We observed that these identified neurons are generated together, and that their axons first arrive in the spinal cord together. We suggest that the selection of different axonal pathways by these neurons does not depend on the time that they develop.
D000367:Age Factors; D000818:Animals; D001921:Brain / Q000196:embryology; D003530:Cyprinidae / Q000196:embryology*; D006735:Horseradish Peroxidase; D009420:Nervous System / Q000196:embryology*; D009474:Neurons / Q000166:cytology; D013116:Spinal Cord / Q000196:embryology; D013936:Thymidine; D015027:Zebrafish / Q000196:embryology*
D006735:Horseradish Peroxidase; D013936:Thymidine