Dopamine agonists for reducing depression associated with hyperprolactinemia.
Nine women with prolactinomas studied over 20 weeks were depressed as determined by three separate self-rating scales. The depression improved with bromocriptine or pergolide. Acute depression recurred and prolactins increased after discontinuation of the medication.
D000704:Analysis of Variance; D001971:Bromocriptine / Q000009:adverse effects / Q000627:therapeutic use*; D003863:Depression / Q000188:drug therapy* / Q000209:etiology; D003866:Depressive Disorder / Q000209:etiology; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D008297:Male; D010479:Pergolide / Q000009:adverse effects / Q000627:therapeutic use*; D010911:Pituitary Neoplasms / Q000378:metabolism*; D011388:Prolactin / Q000032:analysis / Q000378:metabolism*
D010479:Pergolide; D001971:Bromocriptine; D011388:Prolactin