Congenital fibrosarcoma. Preoperative chemotherapy and conservative surgery.
Three cases of congenital fibrosarcoma are reported. The use of preoperative chemotherapy, a VAC regimen, allowed conservative surgery in two of them. The three children are well, with no evidence of disease and without sequelae after completion of postoperative chemotherapy.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000151:congenital* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D005260:Female; D005354:Fibrosarcoma / Q000151:congenital* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012272:Ribs / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000151:congenital* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D014750:Vincristine / Q000008:administration & dosage
D003609:Dactinomycin; D014750:Vincristine; D003520:Cyclophosphamide