Relationship between functional and histological changes in chronic pancreatitis.
The results of the secretin-CCK test were compared with the histological findings of pancreatic tissue resected in 25 patients with chronic pancreatitis. Secretin-CCK test results were interpreted with the use of discriminant analysis, yielding a quantitative score for each patient. Histological findings were recorded according to a semiquantitative scale. Fairly high correlation coefficients were found between secretin-CCK test results and severity of acinar atrophy and small dilatation. These findings emphasize the importance of the secretin-CCK test for diagnostic and follow-up purposes in chronic pancreatitis.
D000328:Adult; D002766:Cholecystokinin; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D010179:Pancreas / Q000473:pathology*; D010195:Pancreatitis / Q000175:diagnosis*; D012633:Secretin
D012633:Secretin; D002766:Cholecystokinin