title: [Autoimmune hemolytic anemia complicating homozygotic beta- thalassemia].
abstract: Four cases of auto-immune hemolytic anemia complicating the course of intermediate or major beta-thalassemia syndromes are reported in children. Ages ranged from 2 to 13 years. Two children had undergone a splenectomy. The direct Coombs test was positive of the IgG +/- complement or complement alone type. Corticosteroid therapy was beneficial in the 3 children who were given this treatment. Coombs test became negative after intervals ranging from 15 days to 8 months.
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000209:etiology*; D002675:Child, Preschool; D005260:Female; D006720:Homozygote; D006801:Humans; D007223:Infant; D008297:Male; D013789:Thalassemia / Q000150:complications* / Q000175:diagnosis / Q000235:genetics
vernacular_title: Anémie hémolytique auto-immune compliquant la beta-thalassémie homozygote.