title: Pharmacology of lemongrass (Cymbopogon citratus Stapf). II. Effects of daily two month administration in male and female rats and in offspring exposed "in utero".
abstract: An infusion (abafado) prepared from leaves of lemongrass (Cymbopogon citratus Stapf) administered orally to adult rats for 2 months, in doses up to 20 times larger than the estimated corresponding human dosage, did not induce any effect which could be taken as evidence of toxicity. An absence of effects was also noted in male and female rats and in their offspring when the abafado was administered prior to mating or during pregnancy. These data strongly suggest that lemongrass, as used in Brazilian folk medicine, has no toxic properties.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001938:Brazil; D004971:Estrus / Q000187:drug effects; D005260:Female; D005298:Fertility / Q000187:drug effects*; D006801:Humans; D008297:Male; D008431:Maternal-Fetal Exchange; D008519:Medicine, Traditional; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000633:toxicity*; D010946:Plants, Medicinal; D006109:Poaceae; D011247:Pregnancy; D051381:Rats; D013723:Teratogens
chemical_list: D010936:Plant Extracts; D013723:Teratogens