Study of binding of twelve cephalosporins to human serum albumin by fluorescent probe technique.
The binding constants and per cent binding of twelve cephalosporins to human serum albumin were determined using a fluorescence probe method. Binding is enhanced by hydrophilic substitutions on the basic molecules.
D000817:Anilino Naphthalenesulfonates; D002511:Cephalosporins / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D011485:Protein Binding; D012709:Serum Albumin / Q000378:metabolism*
D000817:Anilino Naphthalenesulfonates; D002511:Cephalosporins; D012709:Serum Albumin; C027132:1-anilino-8-naphthalenesulfonate