Induction of heat shock proteins in young and senescent human diploid fibroblasts.
When human diploid fibroblasts, TIG-1, reached the end of their proliferative lifespan in vitro, they still could synthesize proteins with molecular weight of about 70,000, 85,000 and 116,000 following the heat shock at 46 degrees C for 10 min as well as young cells did so.
D000375:Aging; D002455:Cell Division; D002478:Cells, Cultured; D004171:Diploidy; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D006360:Heat-Shock Proteins / Q000096:biosynthesis*; D006801:Humans
D006360:Heat-Shock Proteins