Cross-reaction between Streptococcus pneumoniae and group C streptococcal latex reagent.
The extent of cross-reactivity between Streptococcus pneumoniae and two commercial streptococcal latex grouping reagents was examined. Cross-reactivity with the group C latex reagent was demonstrated in 91% (20 of 22) of blood cultures tested directly and in 97% (73 of 75) of clinical isolates of various serotypes tested after enzymatic extraction. This is important in the clinical laboratory because it may lead to erroneous identification of organisms present in blood cultures.
D000942:Antigens, Bacterial / Q000032:analysis / Q000276:immunology*; D001769:Blood / Q000382:microbiology; D003429:Cross Reactions; D006801:Humans; D007841:Latex Fixation Tests; D013291:Streptococcus / Q000276:immunology* / Q000302:isolation & purification; D013296:Streptococcus pneumoniae / Q000276:immunology* / Q000302:isolation & purification
D000942:Antigens, Bacterial