title: [Experimental study of the possible use of sodium dehydroacetate as a food additive].
abstract: The results are presented of toxico-hygienic investigations of dehydroacetic acid sodium salt (DHASS) proposed as a food additive. The compound toxicity values have been assessed, and late results of the preservative influence on the body of experimental animals after its oral intake have been studied. An approximate value of daily intake (AVDI) of the compound has been calculated. It has been shown that DHASS cannot be recommended as a food additive because its technologically effective concentrations are significantly higher than AVDI.
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D005520:Food Preservatives / Q000008:administration & dosage / Q000633:toxicity*; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D009154:Mutation; D011714:Pyrans / Q000633:toxicity*; D011753:Pyrones / Q000633:toxicity*; D051381:Rats
chemical_list: D005520:Food Preservatives; D011714:Pyrans; D011753:Pyrones; C027493:dehydroacetic acid
vernacular_title: Eksperimental'noe izuchenie vozmozhnosti ispol'zovaniia natrievoĭ soli degidratsetovoĭ kisloty v kachestve pishchevoĭ dobavki.