Granuloma-related hypercalcemia in lipoid pneumonia.
A patient with hypercalcemia, suppressed serum PTH levels, and elevated serum levels of calcitriol was found to have a granulomatous lipoid pneumonia due to chronic aspiration of a "vaporizing ointment." After the surgical removal of the largest granuloma, the serum calcium and calcitriol levels rapidly returned to normal. This is a new instance of granuloma-induced hypercalcemia, probably mediated by the activation of vitamin D by cells of the granulomatous reaction.
D000368:Aged; D002117:Calcitriol / Q000097:blood; D002118:Calcium / Q000097:blood; D006099:Granuloma / Q000097:blood / Q000150:complications* / Q000601:surgery; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D008171:Lung Diseases / Q000097:blood / Q000150:complications* / Q000601:surgery; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D011015:Pneumonia, Aspiration / Q000150:complications*; D011017:Pneumonia, Lipid / Q000097:blood / Q000150:complications*; D014807:Vitamin D / Q000502:physiology
D010281:Parathyroid Hormone; D014807:Vitamin D; D002117:Calcitriol; D002118:Calcium