title: [Therapy-induced fluorosis--damage or goal?].
abstract: Report on 3 female patients who, after treatment of an osteoporosis with sodium fluoride, have developed a skeletal fluorosis. The proof was performed radiologically, histologically and by means of fluoride analysis in the bone ash. The diagnosis was made accidentally. Complaints relating to this are not mentioned. Osteosclerosis after fluoride therapy is no iatrogenically damage for the patient, but the aim of the therapy for the prevention of osteopenic fractures.
mesh_terms: D000328:Adult; D000368:Aged; D004305:Dose-Response Relationship, Drug; D005260:Female; D005598:Fractures, Spontaneous / Q000517:prevention & control; D006801:Humans; D010024:Osteoporosis / Q000188:drug therapy*; D010026:Osteosclerosis / Q000139:chemically induced*; D012969:Sodium Fluoride / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D012969:Sodium Fluoride
vernacular_title: Therapiebedingte Fluorose--Schaden oder Ziel?