title: Photosensitivity to the nonsteroidal anti-inflammatory drug piroxicam.
abstract: Two cases of photosensitivity to the nonsteroidal anti-inflammatory agent piroxicam are described. The action spectrum appears to be in the ultraviolet A (UVA) range (320 to 400 nm). Hallmarks of the photosensitivity reaction include an acute eczematous dermatitis with frank vesicle formation clinically and spongiosis and a perivascular mononuclear cell infiltrate histologically. Piroxicam and other nonsteroidal anti-inflammatory drugs are capable of inducing cutaneous photosensitivity.
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010787:Photosensitivity Disorders / Q000139:chemically induced* / Q000473:pathology; D010894:Piroxicam / Q000009:adverse effects*
chemical_list: D010894:Piroxicam