Abnormalities in dermal vessel walls of normal skin of patients with essential mixed cryoglobulinemia. An ultrastructural study.
Immune deposits have been detected in vessel walls of forearm normal skin of patients with essential mixed cryoglobulinemia. No inflammatory cells were present around the vessel walls. These findings suggest that simple deposition of immune complexes is not sufficient to trigger an inflammatory reaction.
D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis; D001485:Basement Membrane / Q000648:ultrastructure; D001808:Blood Vessels / Q000473:pathology / Q000648:ultrastructure*; D002462:Cell Membrane / Q000648:ultrastructure; D003449:Cryoglobulinemia / Q000097:blood / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D012867:Skin / Q000098:blood supply* / Q000648:ultrastructure
D000936:Antigen-Antibody Complex