title: [Antroduodenal coordination].
abstract: The function of the antro-duodenal segment depends on the spatial and temporal sequence of contractions. This process can be defined as antroduodenal coordination. There is no constantly increased pressure in the antro-duodenal transition zone. During the interdigestive phase a coordination of gastral and duodenal motility, gastric acid secretion and bile-flow into the duodenum can be demonstrated. During phase II of the interdigestive phase a pressure gradient, proximal and distal, is observed in the gastroduodenal transition zone with peak values in the pyloric and duodenal bulb area. Cisapride and metoclopramide stimulate antral and duodenal motility, cisapride causes a significant increase in gastroduodenal coordination.
mesh_terms: D000818:Animals; D001647:Bile Acids and Salts / Q000502:physiology; D020117:Cisapride; D004063:Digestion / Q000187:drug effects; D004386:Duodenum / Q000502:physiology*; D004943:Esophagogastric Junction / Q000502:physiology; D005746:Gastric Emptying / Q000187:drug effects; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D008365:Manometry; D008787:Metoclopramide / Q000494:pharmacology; D009037:Motilin / Q000502:physiology; D009130:Muscle, Smooth / Q000502:physiology; D010189:Pancreatic Juice / Q000502:physiology; D010880:Piperidines / Q000494:pharmacology; D011706:Pyloric Antrum / Q000502:physiology*
chemical_list: D001647:Bile Acids and Salts; D010880:Piperidines; D009037:Motilin; D008787:Metoclopramide; D020117:Cisapride
vernacular_title: Antroduodenale Koordination.