Prolonged echoviral meningitis in a cancer patient with normal serum immunoglobulins.
This is a report of prolonged meningitis caused by echovirus type 20 in a patient with rhabdomyosarcoma. It represents one of the few documented cases of delayed clearance of echovirus in the cerebrospinal fluid in a patient with normal serum immunoglobulins. The case illustrates the prolonged clinical course of echoviral meningitis in a patient receiving cytotoxic drug therapy, and it suggests that factor(s) other than humoral antibodies may be involved in the elimination of echovirus from the central nervous system.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D002675:Child, Preschool; D004457:Echovirus Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000150:complications*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007278:Injections, Spinal / Q000009:adverse effects; D008297:Male; D008587:Meningitis, Viral / Q000097:blood / Q000134:cerebrospinal fluid / Q000150:complications*; D012208:Rhabdomyosarcoma / Q000097:blood / Q000150:complications* / Q000188:drug therapy
D007136:Immunoglobulins