The effect of pirenzepine on gallbladder emptying in humans.
The effect of the selective antimuscarinic agent, pirenzepine, on gallbladder function was studied in six healthy volunteers, using 99mTc HIDA (N-[2,6-diethylthenyl] carbamoylmethyl iminodiacetic acid) hepatobiliary scanning. Pirenzepine, in doses that inhibit gastric acid secretion, did not alter gallbladder emptying responses to sham feeding stimulation or to a test meal.
D000328:Adult; D004435:Eating; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007098:Imino Acids; D008297:Male; D010890:Pirenzepine / Q000494:pharmacology*; D011877:Radionuclide Imaging; D013667:Technetium; D019780:Technetium Tc 99m Lidofenin
D007098:Imino Acids; D010890:Pirenzepine; D019780:Technetium Tc 99m Lidofenin; D013667:Technetium