[Inhibition of the development of adjuvant arthritis in rats as affected by vitamin E].
The experiments on rats have shown that preliminary oral administration of vitamin E significantly suppressed generalization, but not development of adjuvant-induced arthritis. Oral vitamin E administration beginning one day after the onset of arthritis inhibited the development and generalization of the disease. Vitamin E had no effect on serum lysosomal enzyme activity, but markedly depressed lipid peroxidation.
D000818:Animals; D001168:Arthritis / Q000209:etiology*; D001169:Arthritis, Experimental / Q000201:enzymology / Q000209:etiology* / Q000517:prevention & control; D001192:Arylsulfatases / Q000097:blood; D001835:Body Weight / Q000187:drug effects; D003864:Depression, Chemical; D004353:Drug Evaluation, Preclinical; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology; D008297:Male; D009113:Muramidase / Q000097:blood; D051381:Rats; D013997:Time Factors; D014810:Vitamin E / Q000494:pharmacology* / Q000627:therapeutic use
D014810:Vitamin E; D001192:Arylsulfatases; D009113:Muramidase
Podavlenie razvitiia ad''iuvantnogo artrita u krys pod vliianiem vitamina E.