title: A new method for intraoral patch testing.
abstract: Intraoral patch testing was performed in 3 subjects, 2 of whom were contact sensitive to nickel. Maxillary acrylic plates carrying test pieces containing 66% nickel were applied for 48 h, and readings were performed 24 h after removal. Few if any clinical signs were detected, but biopsies from the mucosal contact sites showed lichenoid reactions. Biopsies from control sites showed no or slight non-specific inflammatory reactions.
mesh_terms: D000328:Adult; D003722:Dental Alloys / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009059:Mouth Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology; D009532:Nickel / Q000009:adverse effects; D010328:Patch Tests / Q000295:instrumentation / Q000379:methods*; D012882:Skin Tests / Q000379:methods*
chemical_list: D003722:Dental Alloys; D009532:Nickel