Priapism and psychotropic medication.
Priapism is a rare but serious adverse effect of psychotropic drugs resulting from their peripheral alpha-adrenoreceptor blocking action. Two patients developed this during treatment with oral phenothiazines: one was treated surgically with a venous shunt, and the second case resolved after intracavernosal injection of an alpha-adrenoreceptor stimulating drug.
D000328:Adult; D002719:Chlormethiazole / Q000009:adverse effects*; D002746:Chlorpromazine / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009110:Munchausen Syndrome / Q000188:drug therapy; D011317:Priapism / Q000139:chemically induced*; D011395:Promazine / Q000009:adverse effects; D012559:Schizophrenia / Q000188:drug therapy
D002719:Chlormethiazole; D011395:Promazine; D002746:Chlorpromazine