Pulmonary ceroidosis.
We describe a patient with pulmonary ceroid histiocytosis. Skin pigmentation, chest x-ray film and laboratory findings were normal. Only pulmonary function tests were abnormal (TLC = 63 percent, DLco = 52 percent). Based on these functional data, the patient was submitted to a lung biopsy by thoracotomy. Brown pigmented histiocytes were shown occupying alveolar spaces. Similar brown pigmented hepatocytes were seen in the liver biopsy.
D000328:Adult; D001853:Bone Marrow / Q000378:metabolism; D002566:Ceroid / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006644:Histiocytes / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D008099:Liver / Q000378:metabolism; D008175:Lung Neoplasms / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D008206:Lymphatic Diseases / Q000188:drug therapy / Q000378:metabolism* / Q000473:pathology; D010860:Pigments, Biological / Q000378:metabolism*; D012129:Respiratory Function Tests
D002566:Ceroid; D010860:Pigments, Biological