[Digitalis poisoning in children. Treatment with anti-digoxin Fab antibody fragments. Apropos of a case and a discussion of therapeutic indications].
We report one case of Digoxin intoxication in a child treated with Fab Fragments of Digoxin-Specific antibodies (Fabad), although there was no evidence of early life threatening complications. The efficacy of this treatment, which prevents further complications as well as its safety, represent strong arguments to treat children at the early stage of the intoxication in order to avoid temporary cardiac pacing.
D000906:Antibodies / Q000627:therapeutic use*; D002675:Child, Preschool; D004077:Digoxin / Q000097:blood / Q000506:poisoning*; D004562:Electrocardiography; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000627:therapeutic use*; D008297:Male; D011188:Potassium / Q000097:blood
D000906:Antibodies; D007140:Immunoglobulin Fab Fragments; C050199:digoxin antibodies Fab fragments; D004077:Digoxin; D011188:Potassium
Intoxication digitalique chez l'enfant. Traitment par fragments Fab d'anticorps anti-digoxine. A propos d'un cas et discussion des indications thérapeutiques.