Posterior lobe of the pituitary: identification by lack of chemical shift artifact in MR imaging.
The posterior aspect of the normal sellar content usually displays high intensity signal on T1-weighted images. The shape, size, and location of this high intensity seem to be compatible with the posterior lobe of the pituitary gland. But fatty tissues such as intrasellar fat pad or fatty marrow of the dorsum sellae or both must be excluded as other possible sources of this high intensity signal. Two sellar phantoms were prepared. Both included high intensity posterior parts, one due to high concentration of a paramagnetic ion and the other due to fat. Magnetic resonance imaging of these phantoms showed that the fatty component was accompanied by distinct chemical shift artifacts in a predictable way. The absence of chemical shift artifact in the sellar content of normal volunteers excluded the fatty tissue as representing the high intensity posterior part. The high intensity posterior part of the normal sellar content appears to represent the posterior lobe of the pituitary gland.
D000273:Adipose Tissue / Q000033:anatomy & histology; D000328:Adult; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008961:Models, Structural; D010904:Pituitary Gland, Posterior / Q000033:anatomy & histology*; D012658:Sella Turcica / Q000033:anatomy & histology