Scleredema in an infant.
A 3-month-old infant with scleredema had associated cytomegalovirus pneumonia with a rapidly fatal course. Because differentiation of scleredema from scleredema neonatorum, subcutaneous fat necrosis, and scleroderma may be difficult, histologic diagnosis is important. Cetylpyridinium chloride was used successfully as a fixative to demonstrate acid mucopolysaccharides histologically.
D001706:Biopsy; D003937:Diagnosis, Differential; D005218:Fat Necrosis / Q000175:diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D012592:Scleredema Adultorum / Q000175:diagnosis; D012593:Sclerema Neonatorum / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D012867:Skin / Q000473:pathology