[Relation between changes in macro- and microcirculation and lymph flow in the extremities of the cat after histamine infusion].
In experiments on the cat isolated hindlimb perfused with a constant flow, it was shown that against the background of dilatation of arteries under effect of histamine, venous outflow from the hindlimb increased after 0.05-0.1 microgram X min-1 X kg-1 histamine and decreased after a higher doses. In lower doses of histamine, a decrease of capillary hydrostatic pressure prevailed whereas in higher doses it was increased. The capillary filtration coefficient increased proportionally to the dose of histamine. The transcapillary fluid exchange involved no alteration in lymph formation in the hindlimb, the lymph being stored in lymphatic ducts.
D000818:Animals; D001775:Blood Circulation / Q000187:drug effects*; D001794:Blood Pressure; D002415:Cats; D004548:Elasticity; D005260:Female; D006614:Hindlimb / Q000098:blood supply*; D006632:Histamine / Q000494:pharmacology*; D006874:Hydrostatic Pressure; D008208:Lymphatic System / Q000187:drug effects*; D008297:Male; D008833:Microcirculation / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects; D014680:Veins / Q000187:drug effects
D006632:Histamine
Vzaimootnoshenie sdvigov makro- i mikrotsirkuliatsii s limfotokom v konechnosti koshki pri infuzii gistamina.