title: Biomechanical properties of human intervertebral discs subjected to axial dynamic compression--influence of age and degeneration.
abstract: This investigation was performed to study biomechanical properties of human intervertebral discs as a function of age. 178 specimens from 21 spinal sections (Th9-S1, 5-84 yr) were subjected to axial dynamic compression; the load being 950 +/- 540 N. The results revealed three distinct age ranges: From the first to the middle of the third decade: axial deformability decreases within the thoracic region, and remains almost constant within the lumbar spine; creep decreases in both parts. From the middle of the third to the beginning of the sixth decade: the biomechanical behavior scarcely alters. Afterwards: axial deformability remains unchanged; creep, however, again increases within the lumbar spine. The results reveal the discs behave most efficiently within the age range where the incidence of back pain is maximal.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D001834:Body Water / Q000378:metabolism; D001846:Bone Development; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007403:Intervertebral Disc / Q000033:anatomy & histology / Q000378:metabolism / Q000502:physiology*; D008875:Middle Aged; D010812:Physical Stimulation