title: Caffeine stimulates in vivo overall cell metabolism. Microcalorimetric measurement of heat production in human platelets.
abstract: The influence of caffeine on overall cell metabolism was studied in human platelets by measurement of cell heat production rate. One hour after administration of 100-200 mg of caffeine, corresponding to 1-2 cups of coffee, significantly increased values (p less than 0.001) were found, 12 +/- 7%. A return to normal values was noted 1 hour later. The cell metabolic stimulation is presumably due to increased catecholamines. A temporary significant rise in systolic (p less than 0.02) and diastolic (p less than 0.05) blood pressure was observed 1 hour after ingestion of caffeine.
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D001833:Body Temperature Regulation; D002110:Caffeine / Q000494:pharmacology*; D002151:Calorimetry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D002110:Caffeine