Fatal water intoxication, schizophrenia, and diuretic therapy for systemic hypertension.
Clinical and morphologic findings are described in a 37-year-old hypertensive man with chronic schizophrenia who had two well-documented episodes of water intoxication. The use of diuretics for control of systemic hypertension in the setting of chronic schizophrenia appears ill-advised.
D000328:Adult; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects* / Q000627:therapeutic use; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D008297:Male; D012559:Schizophrenia / Q000150:complications*; D014869:Water Intoxication / Q000209:etiology*
D006852:Hydrochlorothiazide