title: NONLIN84/PCNONLIN: software for the statistical analysis of nonlinear models.
abstract: A new software package, NONLIN84, has been developed for the analysis of general nonlinear models including pharmacokinetic models. NONLIN84 is easier to use than the older NONLIN77, and can handle a wider class of estimation problems, such as maximum likelihood estimation involving iterative reweighting. Two large libraries of pharmacokinetic models are distributed with NONLIN84 and can be accessed by simply specifying a model number. A companion program, PCNONLIN, runs on DOS based microcomputers and retains most of the features of NONLIN84.
mesh_terms: D006801:Humans; D007700:Kinetics; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D012984:Software
chemical_list: D004364:Pharmaceutical Preparations