Relationship between arterial blood pressure and plasma norepinephrine levels in a patient with neurogenic hypertension.
This study examined the relationship between arterial blood pressure and plasma norepinephrine levels during 12 hours of monitored sleep in a 35-year-old man in whom neurogenic hypertension developed immediately after surgical removal of a large hemangioblastoma at the obex region of the cervical-medullary junction. Plasma norepinephrine levels throughout the 12-hour sampling period correlated (r = 0.81, p less than 0.01) with mean arterial blood pressures, suggesting that sleep-related changes in blood pressure were dependent on associated changes in sympathetic nervous system activity in this patient with neurogenic hypertension.
D000328:Adult; D002940:Circadian Rhythm; D004569:Electroencephalography; D006394:Hemangiosarcoma / Q000601:surgery*; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D009638:Norepinephrine / Q000502:physiology; D011183:Postoperative Complications / Q000503:physiopathology*; D012890:Sleep / Q000502:physiology; D013120:Spinal Cord Neoplasms / Q000601:surgery*
D009638:Norepinephrine