[Subacute pneumopathy caused by hydrochlorothiazide. Cytologic study of the broncho-alveolar lavage].
We report a case of diffuse interstitial pulmonary disease in a 73 year old woman treated for moderate hypertension for one year with the combination of hydrochlorothiazide (50 mg/day) and Amiloride (5 mg/day). The bronchoalveolar lavage showed a neutrophilia of 23% and a 5.5% eosinophilia. The absence of any other aetiological factor and the favourable outcome on cessation of the sole medication incriminate the latter as an aetiological agent in this interstitial pneumonitis.
D000368:Aged; D000584:Amiloride / Q000009:adverse effects; D001980:Bronchi / Q000166:cytology*; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects*; D008171:Lung Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D011650:Pulmonary Alveoli / Q000166:cytology*; D011859:Radiography; D007507:Therapeutic Irrigation
D006852:Hydrochlorothiazide; D000584:Amiloride
Pneumopathie à l'hydrochlorothiazide d'évolution subaiguë. Etude cytologique du lavage broncho-alvéolaire.