Cloning of cells from synovial membrane for the investigation of rheumatoid arthritis.
In an attempt to make well-defined cell culture systems, a method has been developed to produce clones of cells obtained from the synovial fluid of patients with rheumatoid arthritis and patients with HLA B-27 associated arthritis. A preliminary characterization of the cloned cells based on morphologic appearance, avidity for Sudan black B, phagocytosis of latex particles and E-rosette formation is here described.
D001172:Arthritis, Rheumatoid / Q000473:pathology*; D001391:Azo Compounds; D002999:Clone Cells / Q000166:cytology; D006801:Humans; D009281:Naphthalenes; D010587:Phagocytosis; D012397:Rosette Formation; D013583:Synovial Membrane / Q000166:cytology*
D001391:Azo Compounds; D009281:Naphthalenes; C016118:Sudan Black B