title: Electron-microscopic study of the vestibular dark cells in the crista ampullaris of the guinea pig.
abstract: The ultrastructure of the vestibular dark cells in the crista ampullaris of the guinea pig was observed using both transmission and scanning electron microscopy. The dark cells had numerous vacuoles of varying size and electron density, and also characteristic well-developed basal infoldings. These findings strongly suggest that the dark cells play an important role in fluid transport. Unique meshwork structures were observed on the luminal surface of the dark cells. Otoconia showing varying degree of degeneration were occasionally recognized on and near these structures. Electron microscopy revealed that the meshwork was comprised of cytoplasmic processes in a reticular arrangement. They seem to be engaged in the metabolism of otoconia, and perhaps also in fluid transport.
mesh_terms: D000818:Animals; D005260:Female; D006168:Guinea Pigs; D008297:Male; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D009940:Organoids / Q000648:ultrastructure; D010037:Otolithic Membrane / Q000648:ultrastructure; D012665:Semicircular Canals / Q000502:physiology / Q000648:ultrastructure*