title: [Optimization and optimal control of pharmacokinetics].
abstract: In the literature there does not exist many efficient methods for solving identification and optimal control problems in pharmacokinetics. We present a global optimization method for finding the optimum of functions involving several real variables. This technique can be applied to many identification problems. Furthermore a method of successive derivations for the resolution of optimal control problems associated to compartmental modelling is developed.
mesh_terms: D006801:Humans; D007700:Kinetics; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000097:blood / Q000378:metabolism*
chemical_list: D004364:Pharmaceutical Preparations
vernacular_title: Optimisation et controle optimal en pharmacocinétique.