title: Clinical experience with low dosage of propionohydroxamic acid (PHA) in infected renal stones.
abstract: The use of drugs inhibiting bacterial urease represents an interesting improvement in preventive treatment of renal infected stones. The low dose (120 mg/day) for one week followed by 60 mg/day of propionohydroxamic acid (PHA) has shown excellent anti-urease activity. The nearly normal absence of side effects also allows long-term administration.
mesh_terms: D006801:Humans; D006877:Hydroxamic Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D007669:Kidney Calculi / Q000032:analysis / Q000150:complications*; D008274:Magnesium / Q000032:analysis; D017616:Magnesium Compounds; D010710:Phosphates / Q000032:analysis; D000069877:Struvite; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000209:etiology
chemical_list: D006877:Hydroxamic Acids; D017616:Magnesium Compounds; D010710:Phosphates; C036612:propionohydroxamic acid; D000069877:Struvite; D008274:Magnesium