Primary hyperaldosteronism in pregnancy.
A case is reported of a primigravid woman presenting in midgestation with severe hypertension caused by primary hyperaldosteronism. Symptomatic treatment with an aldosterone blocker, a peripheral vasodilator, and a combined alpha beta-blocker allowed pregnancy to continue to 36 weeks' gestation. Cesarean section for fetal distress resulted in delivery of a dysmature female infant who did well. Further postpartum studies confirmed the presumptive diagnosis made during pregnancy. An adenoma, localized in the right adrenal gland, was surgically removed.
D000236:Adenoma / Q000150:complications / Q000175:diagnosis; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000175:diagnosis; D000328:Adult; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy / Q000209:etiology; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000188:drug therapy*