title: Development of Brugia pahangi infections and lymphatic lesions in male offspring of female jirds with homologous infections.
abstract: The development of Brugia pahangi infections and associated gross lymphatic lesions were compared in male offspring from B. pahangi-infected and uninfected female jirds. The numbers of adult worms recovered did not differ between groups but a greater number of offspring of infected females (92%) developed circulating microfilaraemias than did individuals from uninfected females (50%). Intralymphatic granulomatous thrombi, lymphatic dilatations and lymphatic lesion scores were significantly reduced in offspring from infected mothers.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D002009:Brugia; D004605:Elephantiasis, Filarial / Q000276:immunology*; D005260:Female; D005849:Gerbillinae / Q000469:parasitology*; D008208:Lymphatic System / Q000469:parasitology*; D008209:Lymphedema / Q000276:immunology*; D008297:Male