title: Psychopathology in chronic cocaine abusers.
abstract: A group of 30 hospitalized cocaine abusers were studied, along with 124 hospitalized patients who were dependent upon opiates or central nervous system depressants. DSM-III diagnoses, family history data, demographic characteristics, and measures of current depressive symptomatology were compared in the two groups. Nineteen (63%) of the cocaine abusers met criteria for an Axis I diagnosis other than substance abuse; sixteen (53%) had affective disorder. These figures reflected a significantly higher prevalence rate of affective disorder among the cocaine abusers than among the opiate and depressant abusers. In addition, a significantly higher rate of affective disorder was found in the first degree relatives of the cocaine abusers when compared to the other group. Since these findings suggest that a substantial number of cocaine abusers may be suffering from other psychiatric disorders, careful diagnostic evaluation is indicated in this population.
mesh_terms: D000328:Adult; D002492:Central Nervous System Depressants; D003042:Cocaine; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000150:complications; D019964:Mood Disorders / Q000150:complications* / Q000235:genetics; D009293:Opioid-Related Disorders / Q000150:complications; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D002492:Central Nervous System Depressants; D003042:Cocaine