[Lipid metabolism and the activity of cardiospecific enzymes in diabetes mellitus].
The paper provides representative data on the indices of lipid metabolism and the activity of cardiospecific (lactate dehydrogenase--LDH, creatine phosphokinase--CPK) in patients with diabetes mellitus, Type I and II, (male inhabitants of Kaunas aged 40 to 59) which were compared with similar data on control persons randomly selected from the population during epidemiological surveys. They covered 85.3% of all detected and followed-up patients of this age with diabetes mellitus. Total and HDL cholesterol and triglycerides were determined by the enzymatic methods, LDH by the spectrophotometric method and CPK by the fluorometric method. It was shown that patients with Type II diabetes mellitus (insulin-independent) in addition to a raised concentration of glucose on an empty stomach were characterized by an increase in the level of cholesterol up to 6.34-0.51 mmol/l and especially triglycerides up to 5.98-1.78 mmol/l as compared to the control values (5.39-0.11 and 1.48-0.12 mmol, respectively). The concentration of HDL cholesterol and CPK and LDH activity in the patients did not differ from the control level.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003327:Coronary Disease / Q000097:blood; D003402:Creatine Kinase / Q000097:blood*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008055:Lipids / Q000097:blood*; D008097:Lithuania; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000201:enzymology*; D012306:Risk; D014505:Urban Population
D001786:Blood Glucose; D008055:Lipids; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase
Sostoianie lipidnogo obmena i aktivnosti kardiospetsificheskikh fermentov pri sakharnom diabete.