title: An improved morphological technique for the study of cochleotoxicity in guinea pigs.
abstract: Scanning electron microscopy is commonly used to study the normal or pathologically altered cochlear epithelium. It is especially useful for the study of ototoxicity in humans or animals. A cochlear microdissection technique in the guinea pig is presented which permits examination of the whole membranous cochlea with little artefactual damage to the sensory structures under study.
mesh_terms: D000818:Animals; D004210:Dissection / Q000379:methods*; D006168:Guinea Pigs; D007612:Kanamycin / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning; D009925:Organ of Corti / Q000187:drug effects / Q000648:ultrastructure*
chemical_list: D007612:Kanamycin