Renal cell carcinoma originating from dysplastic kidney.
A case of renal cell carcinoma developing from a unilateral dysplastic kidney is presented. The patient was a 33-year-old woman who had lumbago one year and a half prior to death. Multiple abnormal uptakes of 67Ga were seen by scintigraphy. Bone marrow biopsy indicated adenocarcinoma but the primary site was unknown despite extensive examination. At autopsy the carcinoma was wide-spread but no obvious primary-appearing lesion was detected in all the organs except the left kidney. Incidentally the patient had unilateral (left) renal dysplasia. An elaborate study revealed the primary site of the carcinoma within the cystic structure of the dysplastic kidney. This tumor showed reactivity with Dolichos biflorus agglutinin associated antigen (DBA-Ag), soybean agglutinin (SBA), and peanut agglutinin (PNA) which have reactivity with renal tubules.
D000328:Adult; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D003560:Cysts / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities* / Q000473:pathology; D007674:Kidney Diseases / Q000150:complications / Q000473:pathology; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D014057:Tomography, X-Ray Computed