Mechanism of N-acetylpenicillamine (NAPA) potentiation of biliary excretion of methyl mercury in the rat. Influence of glutathione depletors, and metabolization of NAPA and of cysteine in relation to 1-chloro-2,4-dinitrobenzene (DNB) and bromosulphophthalein (BSP) conjugation.
D000818:Animals; D001646:Bile / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D003510:Cyclohexanes / Q000494:pharmacology; D053138:Cyclohexenes; D003545:Cysteine / Q000378:metabolism; D004137:Dinitrochlorobenzene / Q000378:metabolism; D005978:Glutathione / Q000502:physiology*; D008099:Liver / Q000502:physiology; D008767:Methylmercury Compounds / Q000378:metabolism*; D010396:Penicillamine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D013448:Sulfobromophthalein / Q000378:metabolism
D003510:Cyclohexanes; D053138:Cyclohexenes; D004137:Dinitrochlorobenzene; D008767:Methylmercury Compounds; D013448:Sulfobromophthalein; C007193:cyclohexene oxide; C010005:N-acetylpenicillamine; D005978:Glutathione; D010396:Penicillamine; D003545:Cysteine