The determination of pharmacokinetic parameters of ketotifen in steady state in young children.
Ketotifen kinetics at steady state in small children compared to adults show very good absorption for a dose of 2 X daily 1 mg. Relative to adult kinetics, a higher dose in relation to body weight is justified, since a more rapid kinetic pattern was proven for the substance in the volunteer collective tested.
D001249:Asthma / Q000378:metabolism; D001682:Biological Availability; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000378:metabolism; D005260:Female; D006801:Humans; D007665:Ketotifen / Q000097:blood*; D007700:Kinetics; D008297:Male; D012130:Respiratory Hypersensitivity / Q000378:metabolism
D007665:Ketotifen