Effects of pteridines on the filopodia of Dictyostelium discoideum vegetative amoebae.
Living vegetative amoebae of NC-4H Dictyostelium discoideum were studied to determine if a variety of pteridines had any effect on the filopodia. We observed that production, elongation, and branching of these filopodia were stimulated by pteridines that are chemoattractants for cells of this strain. This stimulation occurs at chemotactically effective concentrations and is observed before motility is evident. A relationship between filopodia and chemoattractant signal processing is discussed.
D002633:Chemotaxis; D004023:Dictyostelium / Q000187:drug effects*; D011621:Pteridines / Q000494:pharmacology*
D011621:Pteridines