Platelet [3H]imipramine binding in patients with panic disorder.
[3H]imipramine binding to platelets was measured in 17 drug-free panic disorder patients and 14 healthy controls. No difference in Bmax or Kd values was found between the two groups. Patients with a past history of major melancholic depression or severe agoraphobia had similar binding parameters as panic disorder patients without a history of depression or severe agoraphobia.
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D005239:Fear / Q000502:physiology*; D005260:Female; D006801:Humans; D007099:Imipramine / Q000097:blood*; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000097:blood*; D010200:Panic / Q000502:physiology*; D010698:Phobic Disorders / Q000097:blood*
D007099:Imipramine