HLA antigens in a family with Behçet's syndrome.
A family is described in which 3 of 12 members suffered from Behçet's syndrome. Four members, including the three patients with Behçet's syndrome suffered from recurrent aphthous stomatitis. These four family members possessed the HLA-haplotype HLA A2, B15, Cw3, DR4. However, one relative had inherited the same HLA-haplotype without showing any symptoms of the disease. Genetic influence from the actual HLA-haplotype may interact in manifestation of the syndrome.
D000293:Adolescent; D000328:Adult; D001528:Behcet Syndrome / Q000235:genetics / Q000276:immunology*; D003718:Denmark; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree
D006680:HLA Antigens