title: [Acute encephalopathy following cranial irradiation of previously treated meningeal leukemia].
abstract: The sudden occurrence of an encephalopathic symptomatology within a day following commencement of radiotherapy is demonstrated by a case report of a small child suffering from CNS leukemia. Former intrathecal chemotherapy appears to be a prerequisite for this toxicity. In spite of diuretic therapy the patients condition may worsen initially, but recovery is possible within days. Patient characteristics and disease course identify a new toxicity syndrome, which is not yet familiar.
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D001927:Brain Diseases / Q000209:etiology*; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007938:Leukemia / Q000188:drug therapy / Q000532:radiotherapy* / Q000601:surgery; D008577:Meningeal Neoplasms / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects*
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Akute Enzephalopathie nach Schädelbestrahlung bei vorbehandelter Meningiosis leucaemica.