[Analysis of the immunochemical purity of modern influenza vaccines].
Corpuscular influenza vaccines have been found to contain chick embryo antigens differing from ovalbumin in their antigenic, immunogenic, and allergenic properties. The study has revealed that host antigens are present in vaccines in the form of free contaminants and as substances incorporated into viruses. The vaccine prepared by the method of sorption-elution on red blood cells with subsequent gel chromatography is characterized by the highest antigenic purity.
D000482:Allantois / Q000276:immunology; D000818:Animals; D000941:Antigens / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D002642:Chick Embryo; D002823:Chorion / Q000276:immunology; D007120:Immunochemistry; D009980:Influenza A virus / Q000276:immunology; D007252:Influenza Vaccines / Q000032:analysis* / Q000302:isolation & purification; D010047:Ovalbumin / Q000276:immunology; D014613:Vaccines, Attenuated / Q000032:analysis / Q000302:isolation & purification
D000941:Antigens; D000956:Antigens, Viral; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated; D010047:Ovalbumin
Analiz immunokhimicheskoĭ chistoty sovremennykh grippoznykh vaktsin.