title: Botulism in China.
abstract: During the period 1958-1983, 986 outbreaks of botulism occurred in China, affecting 4,377 individuals and resulting in 548 deaths. The initial cases of botulism were found in Xinjiang province, where the incidence was highest. Outbreaks have occurred in all of the northern provinces and in some of the southern provinces of China. The toxin found most frequently in the northwest region of China was type A; in north China, type B; and in the northeast, type E. The most frequently offending food was home-made strong-smelling preserved bean curd, which was implicated in 74% of the outbreaks. The complex clinical manifestations of botulism can be grouped into those affecting the eyes, the mouth, the pharynx, and the skeletal muscles. Following the institution of effective methods of prevention and treatment, epidemics of botulism in China have been controlled and the mortality rate reduced from 41% (1950s) to 7.6% (1983).
mesh_terms: D000818:Animals; D001904:Botulinum Antitoxin / Q000627:therapeutic use; D001905:Botulinum Toxins / Q000032:analysis; D001906:Botulism / Q000453:epidemiology* / Q000401:mortality / Q000503:physiopathology / Q000628:therapy; D002681:China; D005123:Eye / Q000503:physiopathology; D007887:Fabaceae; D005506:Food Contamination; D006801:Humans; D051379:Mice; D009055:Mouth / Q000503:physiopathology; D009132:Muscles / Q000503:physiopathology; D009500:Neutralization Tests; D010614:Pharynx / Q000503:physiopathology; D010946:Plants, Medicinal; D012621:Seasons
chemical_list: D001904:Botulinum Antitoxin; D001905:Botulinum Toxins