title: Effects of growth hormone substitution on mental performance in adults with growth hormone deficiency: a pilot study.
abstract: Five patients ages 22 to 36 years with growth hormone deficiency received substitution with native human growth hormone and biosynthetic methionyl human growth hormone, 8 IU i.m. three times weekly, for two separate 4-week periods. Before and at the end of each treatment period, five psychometric tests evaluating cognitive functions were performed. The results suggest a beneficial effect of growth hormone on certain cognitive functions. The results were similar for the two hGH preparations.
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D013006:Growth Hormone / Q000031:analogs & derivatives / Q000172:deficiency* / Q000627:therapeutic use; D019382:Human Growth Hormone; D006801:Humans; D008297:Male; D011594:Psychometrics
chemical_list: D019382:Human Growth Hormone; D013006:Growth Hormone