Raman-spectroscopic evidence for the incorporation of alamethicin into dimyristoylphosphatidylcholine bilayers.
The interaction of alamethicin with dimyristoylphosphatidylcholine dispersions was investigated by Raman spectroscopy. The temperature dependence of the C-H stretching spectra demonstrates the incorporation of the polypeptide into the hydrophobic core even in the absence of a transmembrane potential gradient.
D000408:Alamethicin / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D004134:Dimyristoylphosphatidylcholine / Q000378:metabolism*; D008051:Lipid Bilayers / Q000378:metabolism*; D008081:Liposomes / Q000378:metabolism; D013059:Spectrum Analysis, Raman; D013696:Temperature
D000900:Anti-Bacterial Agents; D008051:Lipid Bilayers; D008081:Liposomes; D000408:Alamethicin; D004134:Dimyristoylphosphatidylcholine