title: A trial of povidone-iodine for prevention of contamination of intravenous cannulae.
abstract: A prospective randomized study of 227 intravenous cannulae was undertaken to evaluate the effects of two different skin disinfectants before intravenous cannulation. Patients were divided into two groups. In one povidone-iodine was used as disinfectant while in the other 70% isopropylalcohol was used. Intraluminal contamination rates, colony counts and organisms isolated are presented. We found no correlation between use of cannulae sideport and contamination. It was found that povidone-iodine as a skin disinfectant reduced the intraluminal contamination from 22 to 7.25% (P less than 0.01).
mesh_terms: D000433:1-Propanol / Q000494:pharmacology / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control*; D002408:Catheters, Indwelling / Q000009:adverse effects*; D004202:Disinfectants; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects*; D008826:Microbial Sensitivity Tests; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000494:pharmacology / Q000627:therapeutic use*; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D004202:Disinfectants; D011206:Povidone-Iodine; D000433:1-Propanol; D011205:Povidone