Updating of a method for causality assessment of adverse drug reactions.
The paper represents an update of a method of standardized assessment of causality that was published in 1980. Because of experience that was gained in the meantime, weighting of certain types of information was modified and several weighting tables were introduced to better reflect the influence of type of adverse reaction in the process of evaluation. Comparison of results with the described approach with opinion of medical evaluators is given and discussed.
D064420:Drug-Related Side Effects and Adverse Reactions; D004812:Epidemiologic Methods; D006801:Humans; D011795:Surveys and Questionnaires