title: Carcinoma of the thyroid: differential behaviour in solitary and multinodular tumours.
abstract: One hundred and sixty-three cases of thyroid carcinoma were treated between 1979 and 1983. The cancers were classified as solitary nodules or carcinomas in multinodular goitres according to their clinical presentation. Analysis revealed a significantly higher incidence of T0/T1 in the solitary nodular carcinoma group (P less than 0.001) and a lower incidence of metastatic disease (P less than 0.05) compared with multinodular carcinoma. Survival for the T0/T1 subgroup of solitary nodular carcinoma was significantly better compared with the same subgroup of multinodular carcinoma (P less than 0.05).
mesh_terms: D000328:Adult; D005260:Female; D006044:Goiter, Nodular / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011446:Prospective Studies; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000601:surgery