Purification and amino acid composition of a peptide with molt-inhibiting activity from the lobster, Homarus americanus.
A peptide was isolated and purified from sinus glands of the lobster, Homarus americanus, that was able to decrease circulating titers of ecdysteroids and increase the molt interval of eyestalk-ablated juvenile lobsters. This molt-inhibiting activity was demonstrated to consist of two very closely related peptides by means of high-performance liquid chromatography and gel electrophoresis. By means of amino acid analyses, a molecular weight of approximately 8700 was obtained.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D004441:Ecdysterone / Q000037:antagonists & inhibitors; D007447:Invertebrate Hormones / Q000302:isolation & purification*; D008970:Molecular Weight; D008121:Nephropidae / Q000254:growth & development / Q000378:metabolism*; D010455:Peptides / Q000302:isolation & purification
D000596:Amino Acids; D007447:Invertebrate Hormones; D010455:Peptides; C012445:molt-inhibiting hormone; D004441:Ecdysterone