The Marfan syndrome.
Although the prognosis for a person with the Marfan syndrome is much more favorable than it was a decade ago, this remains a serious and burdensome condition. Early diagnosis is essential and is based on characteristic abnormalities of the musculoskeletal, ocular and cardiovascular systems and a positive family history for the syndrome. Management focuses on recognizing abnormalities and altering the natural history of each clinical manifestation at as young an age as possible. The family physician must be current with therapy and counseling.
D000293:Adolescent; D000328:Adult; D001013:Aorta, Thoracic / Q000473:pathology; D002648:Child; D003376:Counseling; D004108:Dilatation, Pathologic; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000175:diagnosis / Q000235:genetics / Q000473:pathology / Q000628:therapy; D008945:Mitral Valve Prolapse / Q000473:pathology / Q000503:physiopathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000473:pathology; D012306:Risk; D013177:Sports