Intensive hospital monitoring study of intravenous cimetidine.
We studied the frequency of adverse reactions occurring in 1189 patients who received cimetidine intravenously, based on data collected as part of a hospital-based monitoring study of recently marketed drugs. There were 40 patients (3.4%) with adverse reactions, 23 of whom were considered to be "definitely" or "probably" related to cimetidine use and 17 patients in whom a causal association was possible. The most frequently reported reactions were neuropsychiatric disorders in 19 patients (1.6%) and leukopenia in eight patients (0.7%).
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002927:Cimetidine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006761:Hospitals; D006801:Humans; D007262:Infusions, Intravenous; D007970:Leukopenia / Q000139:chemically induced; D008297:Male; D008991:Monitoring, Physiologic; D011605:Psychoses, Substance-Induced / Q000209:etiology; D012737:Sex Factors
D002927:Cimetidine