title: [Heparin-induced thrombopenia].
abstract: Cutaneous necroses, acute renal failure and an adrenocortical insufficiency appeared during heparin therapy in a 47 year old patient with myocardial infarction. The thrombocytes fell to 73,000/microliter and displayed intensified spontaneous aggregation. In histological investigation of the cutaneous necroses, intensive thromboses of the cutaneous and subcutaneous blood vessels were found. The findings indicate a thromboembolic etiology of the acute renal failure and the adrenocortical insufficiency. This case involves a complex example of a heparin-induced thrombopenia with thromboembolic complications.
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced / Q000473:pathology; D000309:Adrenal Insufficiency / Q000139:chemically induced / Q000473:pathology; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy; D009336:Necrosis; D012867:Skin / Q000473:pathology; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000473:pathology; D013923:Thromboembolism / Q000139:chemically induced / Q000473:pathology
chemical_list: D006493:Heparin
vernacular_title: Heparin-induzierte Thrombopenie.