Malignant teratoma in the thyroid gland of an adult: a case report and a review of the literature.
Teratomas in the neck are rare neoplasms. Most occur in the neonate and are benign. In contrast, cervical teratomas in adults are malignant and carry a poor prognosis. Fourteen adult cases have been reported in the world literature, and 11 of these were stated to have arisen in the thyroid gland. A case of a 27-year-old man who presented with a large goiter is reported. A preoperative diagnosis of a malignant thyroid mass was suggested by clinical examination, needle aspiration, and computerized tomography. The patient had a subtotal debulking thyroidectomy. The pathologic specimen confirmed a primary malignant teratoma of the thyroid gland. Despite a combination of radiotherapy and chemotherapy, which were well tolerated, the patient died 2 months after surgery.
D000328:Adult; D003131:Combined Modality Therapy; D006042:Goiter / Q000175:diagnosis; D006801:Humans; D008297:Male; D013724:Teratoma / Q000175:diagnosis* / Q000628:therapy; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000628:therapy; D013965:Thyroidectomy