[Anti-aggregation action of hypochlorite on the thrombocytes].
Sodium hypochlorite at concentrations higher than 1 mM suppresses ADP-dependent aggregation of blood platelets. The effect was associated with the process of cell modification. Blood platelet aggregation may be depressed partially by ADP destruction. Products of ADP-sodium hypochlorite interaction may lead to the induction of blood platelet aggregation, which is not so intensive than the ADP-induced one.
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D004305:Dose-Response Relationship, Drug; D010974:Platelet Aggregation / Q000187:drug effects*; D011817:Rabbits; D012973:Sodium Hypochlorite / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors
D000244:Adenosine Diphosphate; D012973:Sodium Hypochlorite
Protivoagregatsionnoe deĭstvie gipokhlorita na trombotsity.