Secretion of the anti-müllerian hormone by the gonads of experimentally sex reversed female chick embryos.
The gonads of genetically female chick embryos experimentally transformed into testes under the influence of a embryonic testis graft are able to induce in vivo the regression of Müllerian ducts when they are grafted to female embryonic hosts. On the other hand female gonads only transformed into ovotestes are ineffective on the host MDs, as in the case for female gonads. These results show that totally sex reversed gonads have the same properties as a normal testis. In particular they produce the anti-Müllerian hormone, whereas partially reversed gonads do not or only do at a very low level.
D000818:Animals; D054304:Anti-Mullerian Hormone; D002642:Chick Embryo; D012734:Disorders of Sex Development; D005260:Female; D006023:Glycoproteins; D006066:Gonads / Q000378:metabolism*; D006131:Growth Inhibitors; D008297:Male; D009095:Mullerian Ducts / Q000033:anatomy & histology; D010053:Ovary / Q000378:metabolism / Q000637:transplantation; D013735:Testicular Hormones / Q000378:metabolism*; D013737:Testis / Q000378:metabolism / Q000637:transplantation; D014184:Transplantation, Homologous
D006023:Glycoproteins; D006131:Growth Inhibitors; D013735:Testicular Hormones; D054304:Anti-Mullerian Hormone