[Multi-method for determining residues of chemotherapeutics, antiparasitics and growth promotors in foods of animal origin. 2. Determination of nitrofurans and nicarbazin (dinitrocarbanilide components)].
Nitrofurans and dinitrocarbanilide are extracted from food according to the multiresidue method and detected by Reversed-phase-HPLC with UV-detection at 360 nm. Records of the UV-spectra confirm the results qualitatively. Possibilities for further confirmation are discussed. Substances in amounts below 0.01 mg/kg can only be determined with particular care. Statistical confirmation of this method and possible problems are mentioned. An interlaboratory collaborative study confirmed the method: furazolidone, furaltadone, nitrofurazone, nitrofurantoin, and nicarbazin (the dinitrocarbanilide containing component) were added to homogenized eggs in amounts of 0.005-0.150 mg/kg. The procedure can be standardized as an official analytical method at a detection limit of 0.005 mg/kg for nitrofurans and 0.01 mg/kg for nicarbazin.
D000818:Animals; D002224:Carbanilides / Q000032:analysis*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D005506:Food Contamination / Q000032:analysis*; D009528:Nicarbazin / Q000032:analysis*; D009581:Nitrofurans / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet
D002224:Carbanilides; D009581:Nitrofurans; D009528:Nicarbazin
Multimethode zur Bestimmung der Rückstände von Chemotherapeutika, Antiparasitika und Wachstumsförderern in Lebensmitteln tierischer Herkunft. 2. Mitteilung: Bestimmung von Nitrofuranen und Nicarbazin (Dinitrocarbanilid-Komponente).