Preincubation of homogenates from rat brain thalamus and striatum affects the rate of [3H]GABA uptake.
The effect of preincubation of brain homogenates on the subsequent uptake of [3H]GABA was studied in rat thalamus and corpus striatum. The results show that in both brain regions preincubation causes a decrease in the initial rate of [3H]GABA influx, the phenomenon being most evident in the thalamus.
D000818:Animals; D001692:Biological Transport; D003342:Corpus Striatum / Q000378:metabolism*; D005260:Female; D007700:Kinetics; D051381:Rats; D011919:Rats, Inbred Strains; D013788:Thalamus / Q000378:metabolism*; D014316:Tritium; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D014316:Tritium; D005680:gamma-Aminobutyric Acid