Microwave effects on isolated chick embryo hearts.
This study was designed to examine the effects of microwaves on the electric activity of hearts as a means of elucidating interactive mechanisms of nonionizing radiation with cardiac tissue. Experiments were performed on isolated hearts of 9-12-day-old chick embryos placed in small petri dishes. Oxygenated isotonic Ringer's solution at 37 degrees C permitted heart survival. Samples were irradiated at 2.45 GHz with a power density of 3 mW/cm2. The heart signal was detected with a glass micropipet inserted into the sinoatrial node and examined by means of a Berg-Fourier analyzer. Pulsed microwaves caused the locking of the heartbeat to the modulation frequency, whereas continuous wave irradiation might have induced slight bradycardia. Pulsed fields induced stimulation or regularization of the heartbeat in arrhythmia, fibrillation, or arrest of the heart.
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000209:etiology; D002642:Chick Embryo; D005260:Female; D006321:Heart / Q000196:embryology / Q000528:radiation effects*; D006329:Heart Conduction System / Q000528:radiation effects; D006339:Heart Rate / Q000528:radiation effects; D066298:In Vitro Techniques; D008872:Microwaves; D011247:Pregnancy