title: [Necrosis of the optic tract, hypothalamus and brain stem after irradiation of a pituitary adenoma with conventional doses].
abstract: A 56-year-old man had radiation necrosis of the optic pathways, hypothalamus and brainstem following irradiation of a pituitary adenoma at a conventional dose. Factors which predispose to this complication are discussed. Vascular risk factors appear to facilitate radiation induced necrosis, and a reduction of doses is suggested in these cases.
mesh_terms: D000236:Adenoma / Q000532:radiotherapy; D001927:Brain Diseases / Q000209:etiology*; D001933:Brain Stem / Q000528:radiation effects; D006801:Humans; D007031:Hypothalamus / Q000528:radiation effects; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010910:Pituitary Irradiation / Q000009:adverse effects*; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D011388:Prolactin / Q000378:metabolism; D011832:Radiation Injuries / Q000209:etiology*; D011879:Radiotherapy Dosage; D014795:Visual Pathways / Q000528:radiation effects
chemical_list: D011388:Prolactin
vernacular_title: Nécrose des voies optiques, de l'hypothalamus et du tronc cérébral après irradiation d'un adénome hypophysaire a doses conventionnelles.