title: The oxidation of cyclothionine by D-aspartate oxidase.
abstract: Cyclothionine was found to be a substrate for bovine kidney D-Aspartate oxidase. The substrate, prepared chemically as a mixture of the possible stereoisomers, exhibits an inhibition at elevated concentrations. Compounds structurally related to cyclothionine, like TMDA and alpha-alpha'-iminodipropionic acid, have also been assayed with the enzyme.
mesh_terms: D000594:Amino Acid Oxidoreductases / Q000378:metabolism*; D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism; D002417:Cattle; D050804:D-Aspartate Oxidase; D007700:Kinetics; D010084:Oxidation-Reduction; D013644:Tartrates / Q000378:metabolism; D013841:Thiazepines / Q000378:metabolism*
chemical_list: D013644:Tartrates; D013841:Thiazepines; D001224:Aspartic Acid; C010280:perhydro-1,4-thiazepine-3,5-dicarboxylic acid; D000594:Amino Acid Oxidoreductases; D050804:D-Aspartate Oxidase; C029768:tartaric acid