Influence of intestinal microflora on the tryptic activity during lactation in rats.
On comparing germ-free and conventional rats, inactivation of the tryptic activity was found to take place in the caecum of conventional adult rats only. A microbial intestinal inactivation of the tryptic activity was established in suckling conventional rats within 10 days after birth. At 3 weeks of age, suckling germ-free rats were found to have less faecal tryptic activity than their early-weaned littermates.
D000818:Animals; D005260:Female; D005856:Germ-Free Life; D007422:Intestines / Q000382:microbiology*; D007774:Lactation / Q000378:metabolism*; D011247:Pregnancy; D051381:Rats / Q000378:metabolism*; D014357:Trypsin / Q000378:metabolism*
D014357:Trypsin