title: Trazodone-induced mania.
abstract: Two bipolar depressed patients and one unipolar depressed patient developed manic symptoms after receiving trazodone. The symptoms resolved when the treatment was discontinued or reduced. We believe the two bipolar patients are the first cases of this reaction reported in the literature.
mesh_terms: D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy; D003866:Depressive Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D014196:Trazodone / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D014196:Trazodone