title: Transformation of encapsulated Streptococcus pneumoniae.
abstract: We describe the high-efficiency transformation of several virulent, encapsulated isolates of Streptococcus pneumoniae. Transformation was effected by the induction of competence with competence factor and was apparently the result both of inducing noncompetent recipients and overcoming the inhibition imposed by the capsule.
mesh_terms: D001426:Bacterial Proteins / Q000494:pharmacology / Q000502:physiology; D011135:Polysaccharides, Bacterial / Q000502:physiology; D013296:Streptococcus pneumoniae / Q000235:genetics* / Q000472:pathogenicity / Q000502:physiology; D014169:Transformation, Bacterial / Q000187:drug effects; D014774:Virulence
chemical_list: D001426:Bacterial Proteins; D011135:Polysaccharides, Bacterial