Modification of relaxation of isometrically contracting rabbit papillary muscle by calcium, isoprenaline, ouabain and amiloride.
The influence of isoprenaline, ouabain, amiloride, as well as enhanced extracellular Ca on the time course of relaxation of the isometrically contracting papillary muscle was investigated. Under the experimental conditions used the relaxation rate shows different phases, which are modified characteristically. It is concluded that this reflects the different involvement of the Ca transport mechanisms for the relaxation.
D000584:Amiloride / Q000494:pharmacology*; D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D006352:Heart Ventricles / Q000187:drug effects; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology*; D007700:Kinetics; D009200:Myocardial Contraction / Q000187:drug effects*; D010042:Ouabain / Q000494:pharmacology*; D011817:Rabbits; D016276:Ventricular Function
D010042:Ouabain; D000584:Amiloride; D007545:Isoproterenol; D002118:Calcium