Oestrogen-induced desensitization to the negative oestrogen feedback. A mechanism involved in the sex-specific control of gonadotrophin secretion during sexual maturation and in adulthood.
D000818:Animals; D004298:Dopamine / Q000502:physiology; D004958:Estradiol / Q000494:pharmacology*; D004971:Estrus; D005246:Feedback; D005260:Female; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects; D007986:Luteinizing Hormone / Q000378:metabolism*; D008297:Male; D011301:Preoptic Area / Q000187:drug effects*; D051381:Rats; D012727:Sex Characteristics; D012741:Sexual Maturation / Q000187:drug effects
D004958:Estradiol; D007986:Luteinizing Hormone; D004298:Dopamine