title: [Methodology of plasmapheresis in the treatment of patients with hereditary hypercholesterolemia].
abstract: The plasma replacement procedure using the blood cell separator IBM-2997 provides for safe replacement of 2000-3000 ml plasma and a 35 to 45% reduction of the lipid concentration. Plasma replacement with 5% albumin solution per 50 to 70% of total volume allows to maintain normal total plasma protein levels throughout treatment. It was demonstrated that plasmapheresis with plasma ultrafiltrate return makes the procedure more tolerable for the patients, while their own electrolytes, amino acids, vitamins and some enzymes are retained. The reported technique for the discontinuation of the procedure reduces the volume of residual blood in the separation channel, preventing anemia.
mesh_terms: D000328:Adult; D001769:Blood; D002469:Cell Separation; D005260:Female; D005947:Glucose / Q000008:administration & dosage; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D012709:Serum Albumin / Q000008:administration & dosage; D014462:Ultrafiltration
chemical_list: D012709:Serum Albumin; D006493:Heparin; D005947:Glucose
vernacular_title: Metodika plazmafereza v lechenii bol'nykh s nasledstvennoĭ giperkholesterinemieĭ.