title: Simultaneous determination of amfepramon and its two major metabolites in biological fluids by gas liquid chromatography.
abstract: Sensitive and specific procedures based on gas liquid chromatography for the identification, separation and determination of amfepramon (diethylpropion) and its major metabolites ethylaminopropiophenone and diethylnorpseudoephedrine in human plasma, saliva and urine have been described. Acidification of the biological fluid samples has improved the stability of the compounds under conditions of storage.
mesh_terms: D001711:Biotransformation; D001826:Body Fluids / Q000032:analysis*; D002849:Chromatography, Gas; D004053:Diethylpropion / Q000032:analysis* / Q000097:blood / Q000652:urine; D004355:Drug Stability; D006801:Humans; D012463:Saliva / Q000032:analysis
chemical_list: D004053:Diethylpropion