Heart involvement in essential mixed cryoglobulinemia.
Cardiovascular involvement has been investigated in the course of essential mixed cryoglobulinemia (EMC). A direct pathogenetic role of cryoglobulins, due to coexisting coronary risk factors, is difficult to demonstrate. Nevertheless, a clear role of cryoglobulins in determining heart damage was hypothesized. A significant statistical incidence (p less than 0.05) of heart impairment was found in patients affected by EMC compared with an age- and sex-matched control group. Cryoglobulinemic coronary vasculitis found at post-mortem examination further supports this point of view.
D003327:Coronary Disease / Q000150:complications / Q000209:etiology*; D003449:Cryoglobulinemia / Q000145:classification / Q000150:complications* / Q000503:physiopathology; D003450:Cryoglobulins / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000209:etiology
D003450:Cryoglobulins