title: Augmentation of synaptic responses in the dentate gyrus by daily electrical stimulation of the amygdala in cats.
abstract: When the amygdaloid complex was electrically stimulated, polysynaptic evoked potentials were produced in the ipsilateral dentate gyrus of the hippocampal formation. Twenty-four hours after tetanic stimulation of the amygdala, the dentate response to single test pulses was found to be increased in amplitude. Stimulation trains presented at a rate of 1/day had a cumulative effect on the dentate evoked potential, which attained 5-10 times the original response in amplitude. The results imply that the efficiency of synaptic transmission in the amygdalo-hippocampal pathway can be modified, associated with amygdaloid kindling.
mesh_terms: D000679:Amygdala / Q000502:physiology*; D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D005071:Evoked Potentials; D006624:Hippocampus / Q000502:physiology*; D007696:Kindling, Neurologic; D009434:Neural Pathways / Q000502:physiology; D013569:Synapses / Q000502:physiology; D013997:Time Factors