Thiazide-induced hyponatremia.
We have described a case of severe acute hyponatremia developing in a patient who had been taking thiazides for the previous eight months without having any electrolyte abnormalities. The onset of the electrolyte disturbance coincided with a physician-recommended hydration regimen, which we believe unmasked a drug-related impairment of water excretion. Withdrawal of thiazide therapy promptly resulted in water diuresis and rapid correction of the hyponatremia.
D000208:Acute Disease; D000368:Aged; D004326:Drinking; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects*; D007010:Hyponatremia / Q000139:chemically induced*; D008297:Male
D006852:Hydrochlorothiazide