title: Vitreous fluorophotometry in juvenile diabetics after oral fluorescein.
abstract: Vitreous fluorophotometry was performed in young patients (8 to 19 years old) affected by insulin-dependent diabetes mellitus, with no signs of diabetic retinopathy. Oral fluorescein was administered, and measures were used to prevent hypoglycemia during the examination. The results showed a breakdown of the blood-retinal barrier in nine (43%) of the 21 patients. The oral fluorescein method allows a satisfactory evaluation of ocular fluorescence profiles, with minimal risk of systemic side effects.
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000473:pathology*; D005260:Female; D019793:Fluorescein; D005452:Fluoresceins; D005470:Fluorometry; D006801:Humans; D008297:Male; D010783:Photometry; D012171:Retinal Vessels / Q000378:metabolism; D014822:Vitreous Body / Q000473:pathology*
chemical_list: D005452:Fluoresceins; D019793:Fluorescein