31P NMR studies of adenosine-stimulated ATP synthesis in perfused luteinized ovaries.
31P NMR spectroscopy was utilized to study phosphate metabolism of perfused ovaries. In luteinized ovaries, a loss in ATP of approximately 30% with a concomitant acidification was reversed by 50 microM adenosine. The results suggest that in the ovaries, adenosine can serve to regulate ATP concentration during periodic hypoxic challenges.
D000241:Adenosine / Q000494:pharmacology; D000255:Adenosine Triphosphate / Q000096:biosynthesis*; D000818:Animals; D005260:Female; D008183:Luteal Phase; D009682:Magnetic Resonance Spectroscopy; D010053:Ovary / Q000033:anatomy & histology* / Q000378:metabolism; D010477:Perfusion; D010759:Phosphorus Isotopes; D051381:Rats
D010759:Phosphorus Isotopes; D000255:Adenosine Triphosphate; D000241:Adenosine