[Indices of the status of the cholinergic processes in the rat sensorimotor cortex and caudate nucleus at early periods after gamma-irradiation at a dose of 150 Gr].
An insignificant increase in the content of acetylcholine-like substances was registered in the rat brain cortex and caudate nucleus 15 min after whole-body gamma-irradiation with a dose of 150 Gy. After 24 h, the number of these substances appreciably decreased. Total acetylcholinesterase activity in the above brain parts gradually decreased throughout the entire period of observation. These indices changed more markedly in the caudate nucleus than in the cortex of the brain.
D000109:Acetylcholine / Q000378:metabolism*; D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D002421:Caudate Nucleus / Q000378:metabolism* / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D008297:Male; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013003:Somatosensory Cortex / Q000378:metabolism* / Q000528:radiation effects; D013997:Time Factors
D003037:Cobalt Radioisotopes; D000110:Acetylcholinesterase; D000109:Acetylcholine
Issledovanie nekotorykh pokazateleĭ sostoianiia kholinérgicheskikh protsessov v sensomotornoĭ kore i khvostatom iadre golovnogo mozga krys v rannie sroki posle gamma-oblucheniia v doze 150 Gr.