The effect of stretch on sarcoplasmic free calcium of frog skeletal muscle at rest.
The concentration of free calcium in the sarcoplasm of a resting frog skeletal muscle is increased by stretch. The magnitude of the rise in free calcium increased with the degree of stretch and the ambient temperature and it was enhanced by caffeine. This phenomenon might play a role in the twitch potentiation and enhanced metabolic rate evoked by stretch.
D000818:Animals; D002110:Caffeine / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism*; D009119:Muscle Contraction / Q000187:drug effects; D009126:Muscle Relaxation / Q000187:drug effects; D009132:Muscles / Q000187:drug effects / Q000502:physiology*; D009566:Nitrates / Q000494:pharmacology; D011898:Ranidae; D012519:Sarcoplasmic Reticulum / Q000502:physiology*
D009566:Nitrates; D002110:Caffeine; D002118:Calcium