title: Anterior clear spaces in keratoconus.
abstract: Anterior clear spaces were observed prospectively at slit-lamp examination in 26 of 69 consecutive eyes (38%) with keratoconus. Two corneal buttons with this finding were examined by light and electron microscopy and revealed breaks in Bowman's layer. Anterior clear spaces should be considered in the spectrum of clinical findings in keratoconus.
mesh_terms: D003315:Cornea / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007640:Keratoconus / Q000473:pathology*; D008854:Microscopy, Electron; D011446:Prospective Studies