Cell-specific expression of the human parathyroid hormone gene in rat pituitary cells.
The promoter region of the human parathyroid hormone gene was fused to the Escherichia coli neo gene and introduced into GH4C1 rat pituitary and human HeLa cells. Both TATA boxes of the human parathyroid hormone gene accurately directed transcription in GH4C1 cells; the parathyroid hormone promoter was inactive in HeLa cells.
D000818:Animals; D002460:Cell Line; D005796:Genes; D005798:Genes, Bacterial; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D010281:Parathyroid Hormone / Q000235:genetics*; D010911:Pituitary Neoplasms / Q000378:metabolism*; D010957:Plasmids; D011401:Promoter Regions, Genetic; D051381:Rats; D014158:Transcription, Genetic
D010281:Parathyroid Hormone