[Permanent malabsorption of rifampicin in a diabetic with celiac disease].
A 14 year-old boy with coeliac disease and poorly treated diabetes mellitus and pulmonary tuberculosis due to INH resistant BK presented with a permanent malabsorption of rifampicin. Pharmacokinetics of rifampicin was studied after oral administration and intravenous injection. Treatment of diabetes and coeliac disease did not improve the situation. Tuberculosis was cured by pyrazinamide and ethambutol.
D000293:Adolescent; D002446:Celiac Disease / Q000150:complications / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D008286:Malabsorption Syndromes / Q000209:etiology*; D008297:Male; D012293:Rifampin / Q000378:metabolism*; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000378:metabolism
D012293:Rifampin
Malabsorption permanente de la rifampicine chez un diabétique atteint d'une maladie coeliaque.