[Role of adrenergic mechanisms in regulating memory engram retrieval and energy metabolism in the brain structures of the rat].
In conditions of stimulation of adrenergic mechanisms with ephedrine, there was an improvement of the memory engrams reproduction (MER). Blockade of the alpha-adrenergic system by pyrroxan more expressively impeded reproduction of a passive defensive habit in comparison with the action of a beta-adrenolytic, the obsidan. Stimulation of MER processes was accompanied by a parallel activation of glucose-6-phosphate- and 6-phosphategluconatedehydrogenases of pentose path in the tissues of the frontal area of the cerebral cortex and pons Varolii. Blockade of alpha-adrenoreceptors suppressed the activity of the given enzymes in the same structures, while the obsidan suppressed the dehydrogenases of the pentose path only in the frontal zone of the neocortex.
D000818:Animals; D001921:Brain / Q000502:physiology*; D004146:Dioxanes / Q000494:pharmacology; D004734:Energy Metabolism; D004809:Ephedrine / Q000494:pharmacology*; D005625:Frontal Lobe / Q000502:physiology; D006624:Hippocampus / Q000502:physiology; D008568:Memory / Q000187:drug effects / Q000502:physiology*; D011149:Pons / Q000502:physiology; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D011941:Receptors, Adrenergic / Q000502:physiology*
D004146:Dioxanes; D011941:Receptors, Adrenergic; D011433:Propranolol; D004809:Ephedrine; C009143:proroxan
Rol' adrenergicheskikh mekhanizmov v reguliatsii vosproizvedeniia éngramm pamiati i énergeticheskogo obmena v strukturakh golovnogo mozga krys.