title: Patient with malignant hypertension alive after 25 years. A case report.
abstract: An indian man presented in 1960 with malignant hypertension. He was treated with guanethidine (Ismelin; Ciba), when it was first introduced onto the pharmaceutical market, in combination with other hypotensive agents. Therapeutic compliance was excellent and after 25 years of hypotensive therapy the patient still has a good quality of life.
mesh_terms: D000328:Adult; D002740:Chlorothiazide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006145:Guanethidine / Q000627:therapeutic use; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use; D006974:Hypertension, Malignant / Q000188:drug therapy*; D008297:Male; D012110:Reserpine / Q000627:therapeutic use; D013999:Timolol / Q000627:therapeutic use
chemical_list: D006830:Hydralazine; D002740:Chlorothiazide; D013999:Timolol; D012110:Reserpine; D006145:Guanethidine