Expression of a secreted transplantation antigen gene during murine embryogenesis.
We examined the midgestation mouse embryo for transcripts related to the secreted transplantation antigen Q10 and show here that this gene is transcribed in the endoderm of the visceral yolk sac. Its level of expression is highest at day 14 and then declines as development proceeds. Concurrently with the decrease in yolk sac expression, the amount of transcripts accumulating in the fetal liver increases during late embryogenesis.
D000818:Animals; D004622:Embryo, Mammalian / Q000276:immunology*; D005260:Female; D005796:Genes; D006649:Histocompatibility Antigens / Q000235:genetics*; D008099:Liver / Q000276:immunology; D008285:Major Histocompatibility Complex; D051379:Mice; D009693:Nucleic Acid Hybridization; D011247:Pregnancy; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic
D006649:Histocompatibility Antigens; D012333:RNA, Messenger