[Urinary sodium excretion in women with hypertension and various indicators of hemodynamics and pressor hormone levels].
Urinary sodium excretion was assessed in women with essential hypertension as an indicator of dietary sodium consumption. Groups of individuals with low (below 120 mmol/day), medium and high (above 180 mmol/day) excretion were identified. Patients with high sodium excretion levels showed slower withdrawal rates, as well as high total peripheral resistance and low cardiac output values. At the labile hypertension stage, these patients demonstrated an increase in total metabolic sodium owing to its growing residual fraction, and expanded interstitial fluid volume. Changes in renin-angiotensin-aldosterone activity showed close correlation with changes in sodium balance. Urinary adrenaline and noradrenaline excretion decreased in patients with labile hypertension who had the highest sodium excretion levels, and increased considerably in stable hypertension. Hypertension was particularly severe in patients who excreted over 180 mmol sodium daily whereas patients who excreted less than 120 mmol in the presence of stable hypertension had normal values of total metabolic sodium and cardiac output, and moderately elevated peripheral vascular resistance.
D000328:Adult; D004837:Epinephrine / Q000502:physiology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008875:Middle Aged; D009318:Natriuresis; D009638:Norepinephrine / Q000502:physiology; D012084:Renin-Angiotensin System
D009638:Norepinephrine; D004837:Epinephrine
Ekskretsiia natriia s mochoĭ u zhenshchin, bol'nykh gipertonicheskoĭ bolezn'iu, s razlichnymi pokazateliami gemodinamiki i urovnem pressornykh gormonov.