Combination cyclophosphamide, adriamycin, and cis-platinum in recurrent and metastatic cervical carcinoma.
Thirty evaluable patients with recurrent and/or metastatic cervical cancer were treated with a combination of cyclophosphamide, adriamycin, and cis-platinum. We observed no complete response and three partial responses (10%). One year survival rate was 45%. CAP combination did not prove to be more effective than single agent cis-platinum.
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D010440:Peptichemio / Q000008:administration & dosage; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy*
D004317:Doxorubicin; D003520:Cyclophosphamide; D010440:Peptichemio