[Effect of leu-enkephalin on the verbal forms of mental activity in alcoholics and healthy persons].
A neuropsychological method was used to study the effect of a synthetic analog of leu-enkephalin (dalargin) on the verbal forms of psychic processes in 40 examinees (20 healthy volunteers and 20 alcoholic patients). 20 healthy persons receiving placebo, were entered into the control group. The agent was shown to produce a noticeable effect on the condition of the higher psychic functions. It produced a correcting effect with maximum influence on the pathological links of psychic processes. The nature of influence was regulating: administration of the drug resulted in the normalization of the absolute values of experimental indices and their more balanced ratio.
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy / Q000523:psychology*; D004007:Dichotic Listening Tests / Q000379:methods; D004341:Drug Evaluation; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D006801:Humans; D008570:Memory, Short-Term / Q000187:drug effects; D008606:Mental Processes / Q000187:drug effects*; D011581:Psychological Tests; D013997:Time Factors; D014705:Verbal Behavior / Q000187:drug effects*
D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Vliianie leĭ-énkefalina na verbal'nye formy psikhicheskoĭ deiatel'nosti bol'nykh alkogolizmon i zdorovykh lits.