title: [Use of levamisole in the complex treatment of patients with thyrotoxicosis].
abstract: The immune status was studied in patients with a familial nature of thyrotoxicosis and without complicated heredity. Disorders in the immune homeostasis, mostly expressed in thyrotoxicosis of familial nature, were revealed. Proceeding from the above the authors proposed a method of multimodality therapy of thyrotoxicosis with antithyroid drugs and immunomodulator levamisole causing a fast disappearance of the clinical signs of thyrotoxicosis, a decrease in thyroid activity and density and the reduction of the number of surgical interventions. The effect may be probably due to the normalization of the immune status.
mesh_terms: D000276:Adjuvants, Immunologic; D004105:Diiodotyrosine / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D006801:Humans; D007978:Levamisole / Q000008:administration & dosage*; D008713:Methimazole / Q000008:administration & dosage; D013971:Thyrotoxicosis / Q000188:drug therapy* / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D007978:Levamisole; D008713:Methimazole; D004105:Diiodotyrosine
vernacular_title: Primenenie levamizola v kompleksnom lechenii bol'nykh tireotoksikozom.