Computed tomographic findings in fresh (2nd to 4th week) myocardial infarction.
Thirty-seven patients, 2-4 weeks after transmural myocardial infarction, were investigated with ungated CT over a period of 120 min. after an i.v. contrast medium infusion + bolus injection of 0.6-0.9 iodine/kg body mass. Perfusion defect was found in 23/33 (70%) of technically adequate studies, delayed washout in 6/33 (18%) and local deformity of LV in 8/33 (24%). The mass of the perfusion defect assumed to represent the CT infarct size had a mean value of 10.2 g (3.5-25.8), infarct size estimated with CK-MB enzyme release method had a mean value of 14.1 g eq. (2.4-28.2). There was a r = 0.95 rectilinear correlation coefficient (p less than 0.001) between the CT and CK-MB method of infarct size estimation. Infarcts of size less than 6.0 g eq could not have been demonstrated with CT as a perfusion defect. Contrast enhancement of the infarct area was not a reliable feature of infarction.
D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000009:adverse effects; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D003287:Contrast Media