title: Biological properties of the venom of the red-necked keel-back snake (Rhabdophis subminiatus).
abstract: Studies in mice on the biological activity of the venom of the red-necked keel-back snake, Rhabdophis subminiatus, showed that the venom contained a potent Factor X activator and had intense defibrinogenating activity; the overall proteolytic activity of the venom was low, and this correlated well with its negligible fibrinogenolytic and fibrinolytic activities. Only one antivenom tested was shown to have weak neutralizing activity against the venom in mice. This species of snake has recently been added to the schedule of the Dangerous Wild Animals Act, 1976.
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D005170:Factor X / Q000502:physiology; D005337:Fibrin; D005340:Fibrinogen / Q000502:physiology; D007958:Leukocyte Count / Q000187:drug effects; D051379:Mice; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count / Q000187:drug effects; D012910:Snake Venoms / Q000494:pharmacology* / Q000633:toxicity
chemical_list: D012910:Snake Venoms; D005170:Factor X; D005337:Fibrin; D005340:Fibrinogen