Serum isoamylases in liver diseases.
Total serum amylase and its pancreatic and salivary isoamylase activities were studied in serum from 30 normal volunteers and 30 patients with liver disease. Isoenzyme analysis was performed by inhibitor assay and electrophoretic techniques. Six out of 30 patients had total serum amylase activities which exceeded the mean +/- 2 SD value for normal volunteers. The prominent type of isoenzyme was the pancreatic, except for patients with alcoholic cirrhosis. There was no evidence of any other type of isoenzyme by the electrophoretic method, nor was there an age-dependent isoamylase distribution.
D000328:Adult; D000368:Aged; D005260:Female; D006026:Glycoside Hydrolases / Q000097:blood*; D006521:Hepatitis, Chronic / Q000201:enzymology; D006801:Humans; D007517:Isoamylase / Q000097:blood*; D008104:Liver Cirrhosis, Alcoholic / Q000201:enzymology; D008105:Liver Cirrhosis, Biliary / Q000201:enzymology; D008107:Liver Diseases / Q000201:enzymology*; D008297:Male; D008875:Middle Aged
D006026:Glycoside Hydrolases; D007517:Isoamylase