title: [Interaction of the analgesic substance tenoxicam with alcohol and its influence on psychometrically measurable performance].
abstract: Tenoxicam (Ro 12-0068) is a thienothiacine derivate, which proved to be a potent analgesic in preclinical and clinical trials. An interaction of analgesics, especially those with a possible central origin, with the simultaneous intake of alcohol can never be excluded. For this purpose a study was carried out with 12 volunteers, who had given their informed consent, investigating the influence of alcohol on psychometric parameters like reaction time, memory, ability to concentrate, psychomotor skills. The study led to the result that the simultaneous intake of a realistic volume of alcohol has no influence on the psychometrically measurable performance of the volunteers.
mesh_terms: D001288:Attention / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010894:Piroxicam / Q000031:analogs & derivatives* / Q000494:pharmacology; D011594:Psychometrics; D011597:Psychomotor Performance / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects
chemical_list: D010894:Piroxicam; D000431:Ethanol; C032801:tenoxicam
vernacular_title: Untersuchungen zur Interaktion der analgetisch wirkenden Substanz Tenoxicam mit Alkohol und der Einfluss auf die psychometrisch messbare Leistungsfähigkeit.