title: Two fatalities resulting from Tessalon (benzonatate).
abstract: Two fatal cases involving Tessalon (benzonatate) were quantitated by ultraviolet (UV) and high performance liquid chromatography (HPLC). The first case involved an infant found choking; Tessalon perles were found with the child. The second case involved a successful suicide of an 18-year-old that consumed a "handful" of phenytoin and benzonatate and expired within 1 hr of the ingestion. Blood, brain and kidney concentrations are reported. These are believed to be the first two reported cases involving this compound.
mesh_terms: D000293:Adolescent; D000996:Antitussive Agents / Q000378:metabolism / Q000506:poisoning*; D002082:Butylamines / Q000378:metabolism / Q000506:poisoning*; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010672:Phenytoin / Q000506:poisoning; D013056:Spectrophotometry, Ultraviolet; D013405:Suicide
chemical_list: D000996:Antitussive Agents; D002082:Butylamines; C029755:benzonatate; D010672:Phenytoin