[Effect of strophanthin on the status of systemic and cerebral hemodynamics in patients with ischemic stroke].
The effect of strophanthin (S) on the status of the general and cerebral hemodynamics was investigated in 35 patients with ischemic stroke (IS). The central hemodynamics was studied with the help of dye dilution. The blood circulation in the system of the internal carotid artery was determined with the help of ophthalmoplethysmography and ophthalmodynamometry. S was infused intravenously in daily doses of 0.25 ml of 0.05% solution. S had a positive inotropic influence on the myocardium; the diastolic retinal pressure simultaneously decreased while the minute volume of blood in the eyes increased. The authors substantiate the possibility of the direct effect of S on the tonus of the cerebral vessels and advisability of its application in patients with IS even when there are no evident clinical signs of chronic cardiac failure.
D000368:Aged; D001794:Blood Pressure; D001810:Blood Volume; D001921:Brain / Q000098:blood supply; D002545:Brain Ischemia / Q000188:drug therapy*; D002302:Cardiac Output; D005123:Eye / Q000098:blood supply; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D013328:Strophanthins / Q000627:therapeutic use*; D014655:Vascular Resistance
D013328:Strophanthins
Vliianie strofantina na sostoianie obshcheĭ i tserebral'noĭ gemodinamiki u bol'nykh s ishemicheskim insul'tom.