Factors predictive of perinatal outcome in pregnancies complicated by hypertension.
Perinatal outcome and various indicators of perinatal risk were analyzed in a prospective study of 268 pregnant women with hypertension. Poor perinatal outcome was defined by stillbirth (n = 13), neonatal death (n = 2), and in surviving babies, by birth before 32 weeks or a birthweight below 1500 g (n = 13). In multivariate analysis, proteinuria and onset of hypertension between the 27th and 36th weeks of amenorrhea were the only two independent indicators of poor outcome (relative risks of 4.0 and 3.7, p less than 0.001 and p less than 0.01 respectively). Both these indicators were more frequent in mothers with no history of pre-pregnancy hypertension.
D000328:Adult; D005260:Female; D005313:Fetal Death / Q000209:etiology; D006801:Humans; D006973:Hypertension / Q000378:metabolism; D007226:Infant Mortality; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D011507:Proteinuria / Q000652:urine; D012306:Risk; D014527:Uric Acid / Q000097:blood
D014527:Uric Acid