Detection of an alcohol specific product in urine of alcoholics.
A simple procedure, using high performance liquid chromatography, was developed to detect and measure in urine an alcohol specific product, "ASP" indicative of chronic alcohol consumption. One day after hospital admission, the average amount of ASP in urine of alcoholics was 17 times higher than that of control subjects and 5 and 2 times higher after 7 and 14 days of abstinence, respectively. Urinary levels of ASP should be of value in the identification of chronic alcoholism.
D000428:Alcohol Drinking; D000437:Alcoholism / Q000652:urine*; D000447:Aldehydes / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D003404:Creatinine / Q000652:urine; D006801:Humans; D011506:Proteins / Q000032:analysis*
D000447:Aldehydes; D011506:Proteins; D003404:Creatinine