title: [Significance of the bicuspid aortic valve in the incidence of aortic valve defects in adults].
abstract: In 388 patients with severe isolated aortic valve disease bicuspid aortic valves were found in 45% of patients with aortic stenosis and 24% of patients with aortic regurgitation. There was a history of rheumatic fever in 16% and of endocarditis in 7% of these patients. In a group of 110 patients with severe combined aortic and mitral valve disease, 50% had a history of rheumatic fever and bicuspid valves were found in only 12% of the cases. Severe aortic valve disease based on bicuspid valves was most frequently found in the age group 50-69 years. Bicuspid aortic valve is today the most frequent cause of isolated aortic valve disease; it is more common in aortic stenosis but also occurs in aortic regurgitation.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000209:etiology*; D001024:Aortic Valve Stenosis / Q000209:etiology*; D004696:Endocarditis / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000150:complications*; D008946:Mitral Valve Stenosis / Q000150:complications*; D012213:Rheumatic Fever / Q000150:complications; D012214:Rheumatic Heart Disease / Q000150:complications
vernacular_title: Die Bedeutung der bikuspiden Aortenklappen für die Entstehung des Aortenklappenvitiums bei Erwachsenen.