Protein synthesis in the rat seminiferous epithelium during onset of spermatogenesis--an autoradiographic study.
The pattern of protein synthesis in Sertoli and germ cells during the ontogeny of spermatogenesis in the rat was followed by autoradiography using (3H)-Leucine as precursor. The results suggest that the protein synthetic potential of Sertoli cells is greater than that of germ cells at any stage of differentiation. Significantly enough, the ontogeny-related protein synthetic capabilities of the germ cell compartment find a parallel in those reported for the adult rodent. Furthermore, the data support the suggestion that proteins may be transported from Sertoli cells to germ cells.
D000375:Aging; D000818:Animals; D001345:Autoradiography; D005854:Germ Cells / Q000254:growth & development / Q000378:metabolism; D066298:In Vitro Techniques; D007930:Leucine / Q000378:metabolism; D008297:Male; D014176:Protein Biosynthesis; D051381:Rats; D012708:Sertoli Cells / Q000254:growth & development / Q000378:metabolism; D013091:Spermatogenesis; D013737:Testis / Q000254:growth & development* / Q000378:metabolism; D014316:Tritium
D014316:Tritium; D007930:Leucine