[Therapeutic effect of purified components of a turtle spleen extract].
The administration of a spleen extract of Testudo horsfieldi to mice exposed to lethal radiation of 8 Gy was shown to increase the survival rate and to stimulate haemopoiesis and formation of endocolonies in the spleen. The gel filtration method was used to obtain an active fraction which was subjected to chromatography on cation exchanger to give two more fractions. Active was the fraction with basic components.
D000818:Animals; D008297:Male; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000188:drug therapy*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D013154:Spleen / Q000502:physiology*; D014020:Tissue Extracts / Q000627:therapeutic use*; D014426:Turtles / Q000502:physiology*
D011837:Radiation-Protective Agents; D014020:Tissue Extracts
Issledovanie lechebnogo éffekta ochishchennykh komponentov ékstrakta selezenko cherepakhi.