title: [Dedifferentiated superficial bladder cancer with invasion of the lamina propria (pT1 GIII)].
abstract: On the basis of a retrospective investigation in 45 patients with a carcinoma of the epithelium of the urinary tract pT1 GIII and primary conservative therapy the prognostically relevant factors are controlled. The primary multifocality, the positive dysplastic findings of the biopsies of the mucous membrane and the lacking tumour-associated cell infiltration appeared as high risk for recidivation and tumour progression. The size of the tumour was prognostically not relevant. The rate of recidivations was 53.3%, the tumour progression 37.5%. The 3-year survival rate was 65%, the 5-year rate survival 47%. A conservative therapy of the pT1 GIII tumour is recommended, but at the same time a possibly close-meshed control particularly of the high-risk group is demanded.
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002278:Carcinoma in Situ / Q000473:pathology; D003131:Combined Modality Therapy; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery
vernacular_title: Zur Problematik des entdifferenzierten oberflächlichen Harnblasenkarzinoms mit Invasion der Lamina propria (pT1 GIII).