The value of echocardiography in the early diagnosis of myocardial impairment due to connective tissue diseases.
The study comprised 14 patients with systemic lupus erythematosus (SLE) and 12 patients with diffuse scleroderma. Echocardiography ascertained 5 cases of congestive and 1 case of restrictive cardiomyopathy among the patients with SLE, as well as 6 cases with restrictive cardiomyopathy among those with scleroderma. The authors specify two important echocardiographic variables: the E-septum distance and the septal and wall motion after amyl-nitrite test, which reveal the intrinsic contractile properties of the myocardium, allowing an early diagnosis of myocardial impairment, as well as the selection of patients for an efficient treatment with vasodilator drugs.
D002311:Cardiomyopathy, Dilated / Q000175:diagnosis*; D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis*; D004452:Echocardiography; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D012595:Scleroderma, Systemic / Q000150:complications*; D013997:Time Factors