A model of hippocampal learning during classical conditioning.
During classical conditioning of the rabbit blink reflex, a large fraction of the hippocampal pyramidal neurons are recruited to respond to the conditioned stimulus. The summed response of these neurons comes to match the whole time-amplitude profile of nictitating membrane movement, whereas some individual neurons respond only to part of this profile. A model is described which accounts for these data. The model proposes a learning rule to explain neuron recruitment and uses a tapped delay line to account for the temporal learning properties of the system and the spectrum of individual unit responses.
D000818:Animals; D003214:Conditioning, Classical / Q000502:physiology*; D003215:Conditioning, Eyelid / Q000502:physiology*; D004594:Electrophysiology; D006624:Hippocampus / Q000502:physiology*; D008433:Mathematics; D008959:Models, Neurological; D009541:Nictitating Membrane; D011817:Rabbits; D011999:Recruitment, Neurophysiological