[Inhibiting effect of hypoxia on the development of tumor-like formations in the fungus Fusarium bulbigenum var. blasticola].
When cultivating Fusarium bulbigenum var. blasticola on the synthetic Rider media on the primary colonies tumour-like formations appear which are autonomous nondifferentiated cells. They display the resemblance with the real tumours in the following signs: differentiation, polymorphism, unlimited self-maintainance, aerobic glycolysis, etc. It is shown that under conditions of hypoxia, corresponding to the altitude of 2000-1000 m above sea-level the frequency of tumour-like formations decreases by 9-66% as compared to the cultivation conditions at pO2 of atmospheric air.
D000531:Altitude; D000693:Anaerobiosis; D003470:Culture Media / Q000378:metabolism; D005670:Fusarium / Q000166:cytology / Q000254:growth & development*; D010100:Oxygen / Q000378:metabolism*; D010313:Partial Pressure; D013997:Time Factors
D003470:Culture Media; D010100:Oxygen
Ingibiruiushchee vliianie gipoksii na formirovanie opukholepodobnykh obrazovaniĭ u griba Fusarium bulbigenum var. blasticola.