Superior oblique muscle paralysis in the CREST syndrome.
A 54 year old male with the CREST (Calcinosis, Raynauds, Esophageal hypomotility, Sclerodactyly, Telangiectasia) variant of progressive systemic sclerosis (PSS) presented with vertical diplopia diagnosed as a left superior oblique muscle paralysis. Although cranial nerves abnormalities have been reported in PSS, to our knowledge this is the first report of the CREST syndrome in association with a IV nerve palsy in whom no other etiology could be found.
D003389:Cranial Nerve Diseases / Q000150:complications; D004172:Diplopia / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010243:Paralysis / Q000150:complications*; D012595:Scleroderma, Systemic / Q000150:complications*; D013577:Syndrome; D014321:Trochlear Nerve