[Disorders in the status of the vessel-thrombocyte and plasma links of the hemostatic system in the pathogenesis of disseminated intravascular coagulation in ischemic heart disease].
Platelet/vascular and plasma elements of hemostasis were investigated in normal subjects and coronary patients under stimulated emotional stress, following the assessment of vascular wall antithrombogenic properties on the basis of evidence from short-term local vascular ischemia (the cuff test). In normal subjects, vascular wall antithrombotic properties remained unchanged, providing a sufficient anticoagulant and thrombolytic support under emotional stress and thereby protecting the body against thrombosis. Coronary patients showed depressed vascular-wall antiaggregant, anticoagulant and fibrinolytic activity and latent disseminated intravascular microcoagulation that tended to progress under mental stress, creating a risk of intravascular thrombosis.
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D000328:Adult; D001777:Blood Coagulation; D001792:Blood Platelets / Q000502:physiology; D001808:Blood Vessels / Q000503:physiopathology; D003327:Coronary Disease / Q000150:complications* / Q000503:physiopathology; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D006487:Hemostasis; D006801:Humans; D008875:Middle Aged; D009712:Nucleotides, Cyclic / Q000097:blood; D013929:Thromboxane B2 / Q000097:blood
D009712:Nucleotides, Cyclic; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha
Znachenie narusheniia sostoianiia sosudisto-trombotsitarnogo i plazmennogo zven'ev sistemy gemostaza v patogeneze disseminirovannogo vnutrisosudistogo svertyvaniia krovi pri ishemicheskoĭ bolenzni serdtsa.