Cloning and characterization of a rat-specific repetitive DNA sequence.
A 2.1-kb EcoRI fragment of rat DNA has been cloned and sequenced. This fragment contained a repetitive element which was highly specific for rat DNA and widely dispersed throughout the rat genome. The repetitive element is homologous to a sequence found in the 3' end of the rat LINE family. Because of its high degree of species specificity and its heterodisperse distribution, this sequence provided a useful marker for rat DNA in DNA transfection experiments into mouse host cells.
D000818:Animals; D003001:Cloning, Molecular; D004274:DNA, Recombinant / Q000032:analysis*; D006801:Humans; D008322:Mammals / Q000235:genetics; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid; D013045:Species Specificity
D004274:DNA, Recombinant