Serum concentrations of 25-hydroxyvitamin D and vitamin D-binding protein in elderly people. Effects of institutionalization, protein-energy malnutrition and inflammation.
Serum concentrations of 25-hydroxyvitamin D (25-OH-D) and vitamin D-binding protein (DBP) were measured in institutionalized and non-institutionalized elderly people. The institutionalized subjects were found to have low serum 25-OH-D in confirmation of other studies, but their serum DBP levels were similar to those found in non-institutionalized elderly subjects. Serum DBP concentrations were slightly higher in elderly females than in males, while no age dependence was found for DBP. Elderly people with protein-energy malnutrition who lived in their own homes had slightly reduced serum DBP and 25-OH-D levels. Elderly subjects with infections or other diseases causing acute inflammation, as indicated by an elevated serum haptoglobin and C-reactive protein, had normal levels of DBP.
D000328:Adult; D000368:Aged; D003677:Deficiency Diseases / Q000097:blood*; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000097:blood*; D007249:Inflammation / Q000097:blood*; D007326:Institutionalization; D008297:Male; D012016:Reference Values; D014809:Vitamin D-Binding Protein / Q000097:blood*
D004044:Dietary Proteins; D006887:Hydroxycholecalciferols; D014809:Vitamin D-Binding Protein