Effect of garlic oil extract on serum, liver and kidney enzymes of rats fed on high sucrose and alcohol diets.
High levels of alkaline phosphatase and alcohol dehydrogenase were observed in the serum, liver and kidneys of rats fed on high sucrose and high alcohol diets over a period of 75 days. Garlic oil extract fed with any of the diets, significantly lowered the high levels of the two enzymes in the serum, liver and kidneys. This effect may be due to reduced biosynthesis of fatty acids as NADPH, required for the process, is utilised for the metabolism of the oil.
D000426:Alcohol Dehydrogenase / Q000097:blood / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D000431:Ethanol / Q000494:pharmacology*; D005737:Garlic; D007668:Kidney / Q000187:drug effects / Q000201:enzymology*; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains; D013395:Sucrose / Q000494:pharmacology*
D004040:Dietary Carbohydrates; D010936:Plant Extracts; D000431:Ethanol; D013395:Sucrose; D000426:Alcohol Dehydrogenase; D000469:Alkaline Phosphatase