title: Cryofibrinogenaemia and acute gangrene in systemic sclerosis.
abstract: A 49 year old man with systemic sclerosis developed ischaemia of his extremities with massive peripheral gangrene. High levels of circulating cryofibrinogen were detected in the plasma and the significance of these findings is discussed.
mesh_terms: D000208:Acute Disease; D001778:Blood Coagulation Disorders / Q000150:complications*; D003080:Cold Temperature; D003450:Cryoglobulins / Q000032:analysis*; D005340:Fibrinogen / Q000032:analysis*; D015241:Fibrinogens, Abnormal; D005734:Gangrene / Q000209:etiology*; D006801:Humans; D007511:Ischemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000097:blood / Q000150:complications*
chemical_list: D003450:Cryoglobulins; D015241:Fibrinogens, Abnormal; C041874:cryofibrinogen; D005340:Fibrinogen