[Characteristics of the effect of gamma-irradiation on the amino acid composition of collagen as modified by a gaseous atmosphere].
The comparative changes in the amino acid composition of calf skin collagen after gamma-irradiation (doses from 100 to 1,000 Gy) in aqueous solutions under different gas atmospheres (O2, N2O, H2, vacuum) were investigated. The radiochemical yields of collagen amino acid residues destruction were determined. Under O2 (OH X, O2-) most of amino acids are destroyed with higher yields than under N2O. Leucine, valine, isoleucine, phenylalanine, arginine were the exception because of their high reaction rate constants with OH X and hydroxylation reactions. Under H2 (e-aq, H) and in vacuum (e-aq, OH X) the mechanism of collagen radiolysis changed due to its aggregation; the destruction of those amino acids which have high reaction rate constants with water radiolysis products was mainly observed (phenylalanine, tyrosine, histidine).
D000596:Amino Acids / Q000032:analysis*; D003037:Cobalt Radioisotopes; D003094:Collagen / Q000032:analysis / Q000528:radiation effects*; D005720:Gamma Rays; D006859:Hydrogen; D009609:Nitrous Oxide; D010100:Oxygen; D012996:Solutions; D014867:Water / Q000528:radiation effects
D000596:Amino Acids; D003037:Cobalt Radioisotopes; D012996:Solutions; D014867:Water; D006859:Hydrogen; D003094:Collagen; D009609:Nitrous Oxide; D010100:Oxygen
Ob osobennostiakh deĭstviia gamma-izlucheniia na aminokislotnyĭ sostav kollagena pri modifitsiruiushchem vliianii gazovoĭ atmosfery.