Toxic shock syndrome associated with TSST-1 producing coagulase-negative staphylococci.
Coagulase-positive staphylococci have been isolated from more than 95% of cases of toxic shock syndrome (TSS). Toxic shock syndrome toxin-1 (TSST-1) is produced in more than 90% of cases. A case is described of recurrent TSS in which a coagulase-negative staphylococcus was isolated from the vagina and produced TSST-1. No coagulase-positive staphylococci were isolated. Coagulase-negative staphylococci should be considered as causative agents in cases of TSS. Assay for TSST-1 should be performed on coagulase-negative staphylococci obtained from the appropriate clinical sites if no coagulase-positive staphylococci are isolated.
D000328:Adult; D001427:Bacterial Toxins; D003030:Coagulase / Q000032:analysis; D004768:Enterotoxins / Q000032:analysis*; D005260:Female; D006801:Humans; D012772:Shock, Septic / Q000382:microbiology*; D013210:Staphylococcus / Q000201:enzymology / Q000378:metabolism*; D018089:Superantigens; D014621:Vagina / Q000382:microbiology
D001427:Bacterial Toxins; D003030:Coagulase; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal