Influence of computed tomography scanning and lymphography on the management of testicular germ-cell tumours.
Seventy-eight patients with seminoma and 66 patients with teratoma had computed tomography (CT) of the thorax and abdomen performed as part of initial staging following orchidectomy. Four of 65 (6%) seminoma and 13 of 66 (20%) teratoma patients were upstaged by the addition of CT scanning. No seminoma patients with Stage I disease according to abdominal CT and lymphography had an abnormal thoracic CT scan. Seven of 52 (13%) seminoma and 4 of 21 (19%) teratoma patients who were Stage I according to the CT scan had their staging altered by lymphography. CT was of particular value for defining the exact extent and bulk of metastatic disease prior to and following chemotherapy and radiotherapy, prior to surgical excision of residual disease following chemotherapy, and for investigating potential sites of disease relapse. For all patients with teratoma, we recommend CT of the thorax and abdomen, with bipedal lymphography for those with normal CT scans. For seminoma patients, we suggest lymphography followed by abdominal CT and if either is abnormal, thoracic CT.
D004407:Dysgerminoma / Q000000981:diagnostic imaging* / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008220:Lymphography; D008297:Male; D009367:Neoplasm Staging; D013724:Teratoma / Q000000981:diagnostic imaging* / Q000628:therapy; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy; D014057:Tomography, X-Ray Computed