Rare chromosome 20 variants encountered during prenatal diagnosis.
A case with an uncommon heteromorphism in the centromeric region of chromosome 20, var (20) (cen, CBG 50), and a family with a pericentric inversion of chromosome 20, inv (20) (p11.23qll.21), are reported, both detected in amniotic fluid cell cultures. It appears that small pericentric inversions of chromosome 20 have a low risk of recombination.
D000328:Adult; D002503:Centromere / Q000648:ultrastructure; D002869:Chromosome Aberrations; D007446:Chromosome Inversion; D002890:Chromosomes, Human, Pair 20 / Q000648:ultrastructure; D005260:Female; D014644:Genetic Variation; D006801:Humans; D011110:Polymorphism, Genetic; D011247:Pregnancy; D011296:Prenatal Diagnosis