Nonsurgical (conservative) treatment of giant omphalocele. A report of 10 cases.
Between January 1970 and December 1984, 65 patients with a congenital anterior abdominal wall defect were admitted to the Pediatric Surgical Center of the St. Radbound Hospital, Nijmegen, The Netherlands. There were 39 cases of omphalocele. Ten had giant omphalocele, defined as omphalocele that could not be closed primarily. In these cases, a conservative method of treatment was used. The results are reported of these 10 cases of giant omphalocele with special emphasis on mortality, complications, and length of hospital stay. Mean hospital stay was 95 days. Local infection did not present serious problems. Sepsis occurred in half the patients but was managed with antibiotics. There was one case of late volvulus of the stomach. All local applications, if used regularly, gave rise to complications. Two cases of hypothyroidism caused by the application of povidon-iodine and one case of alcohol intoxication were observed. In early years, one child was lost due to mercury poisoning. There was one early and one late death unrelated to the procedure.
D000015:Abnormalities, Multiple; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000627:therapeutic use; D001458:Bandages; D003902:Detergents / Q000008:administration & dosage; D005260:Female; D006554:Hernia, Umbilical / Q000150:complications / Q000151:congenital / Q000628:therapy*; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007902:Length of Stay; D008297:Male
D000890:Anti-Infective Agents; D003902:Detergents