[Changes in the characteristics of glucocorticoid hormone binding in human peripheral blood lymphocytes during myocardial infarct].
Competitive binding was used to determine the number of binding sites to glucocorticoid hormones in peripheral blood leukocytes of normal subjects, patients with unstable angina pectoris and patients with myocardial infarction. A sharp (2-3-fold) increase in the number of binding sites was observed in patients with myocardial infarction during the first 24 hours after the onset of the disease.
D000328:Adult; D000368:Aged; D000789:Angina, Unstable / Q000097:blood; D001665:Binding Sites; D002467:Cell Nucleus / Q000378:metabolism; D003907:Dexamethasone / Q000097:blood; D005260:Female; D005938:Glucocorticoids / Q000097:blood*; D006801:Humans; D008214:Lymphocytes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D011965:Receptors, Glucocorticoid / Q000032:analysis / Q000378:metabolism; D013997:Time Factors
D005938:Glucocorticoids; D011965:Receptors, Glucocorticoid; D003907:Dexamethasone
Izmeneniia kharakteristik sviazyvaniia gliukokortikoidnykh gormonov v limfotsitakh perifericheskoĭ krovi cheloveka pri infarkte miokarda.