Aged venous thrombi: radioimmunoimaging with fibrin-specific monoclonal antibody.
Radioimmunoimaging of fresh canine venous thrombi with a murine monoclonal antibody specific for human and dog fibrin has been reported. Successful imaging of canine deep venous thrombi 1, 3, and 5 days old at the time of antibody injection is reported. Images were positive in all dogs, and the uptake of fibrin-specific antibody was equivalent to that of fresh thrombi.
D000818:Animals; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D004285:Dogs; D005337:Fibrin / Q000276:immunology*; D007457:Iodine Radioisotopes; D011877:Radionuclide Imaging; D013924:Thrombophlebitis / Q000000981:diagnostic imaging*; D013997:Time Factors
D000911:Antibodies, Monoclonal; D007457:Iodine Radioisotopes; D005337:Fibrin