Navigational deficits in weaver mutant mice.
Weaver mutant mice have selective degeneration of cerebellar granule cells. In comparison to normal mice, the weaver mutants made more errors and took a longer time to reach a platform in a water-maze. Results are discussed in terms of a role for the cerebellum in spatial orientation.
D000818:Animals; D002531:Cerebellum / Q000502:physiology; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000502:physiology*; D009949:Orientation / Q000502:physiology*