title: Canine aflatoxicosis: a continuing problem.
abstract: Aflatoxins are hepatotoxic in many species including dogs. In two separate outbreaks, the primary signalment was high morbidity and mortality in hunting dogs presenting with clinical signs of icterus, anorexia and listlessness. Preliminary laboratory examinations revealed toxic hepatitis, bilirubinuria and anemia. In the first case, a feed sample was not available and the diagnosis was established by confirming the presence of significant levels of aflatoxin B1 in tissues. In the second case, cornmeal utilized in formulating the ration contained 511 ng aflatoxin B1 and B2/g. These cases illustrate that aflatoxicosis is a continuing problem despite widespread awareness and testing for aflatoxin.
mesh_terms: D000348:Aflatoxins / Q000032:analysis / Q000097:blood; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D005243:Feces / Q000032:analysis; D008099:Liver / Q000473:pathology; D008297:Male; D000096702:Aflatoxin Poisoning
chemical_list: D000348:Aflatoxins