Ileal atresia and absence of appendix.
A case of ileal atresia with absence of vermiform appendix in a female newborn is reported. At the region about 105 cm from the Treitz's arch, intestinal atresia was observed with an associated V-shaped deformity of the mesentery. Polyp-like protuberance was observed in the area a few centimeters from the blind end of the distal intestine. Histologically, keratinizing squamous cells, bile pigments, lanugo hair, and alcian-blue stained materials and cells were observed in the serosal layer of the tip of the proximal blind segment and mesenterium connecting to this portion. Thrombi were not observed in the mesenterium connecting to the proximal blind segment, gap segment, and distal blind segment. Squamous cells and lanugo hair were found in the green meconium taken from the large intestine. Polyp-like protuberance was surfaced by normal intestinal mucosa, and in its inside there were two layers consisting of folded muscular tissue. In this report, we describe the detailed pathology of ileal atresia and discuss its possible cause.
D000015:Abnormalities, Multiple / Q000473:pathology*; D001065:Appendix / Q000002:abnormalities*; D005260:Female; D006801:Humans; D007082:Ileum / Q000002:abnormalities*; D007231:Infant, Newborn; D007409:Intestinal Atresia / Q000473:pathology*; D008643:Mesentery / Q000002:abnormalities