title: [Radiobiological effect of alpha-emitting nuclides incorporated in the lungs. Microdistribution of radioactive material and the problem of radiation protection].
abstract: A mathematical model has been developed for the microdistribution of the inhaled radioactive aerosol which is retained within the alveolar-pulmonary region. It is shown that the biological effect of the inhaled alpha-emitting aerosols on the lung tissue is not a uniquely defined function of a mean absorbed dose: its value depends on a number of factors responsible for the microdistribution of the radioactive substance within the alveolar region.
mesh_terms: D000280:Administration, Inhalation; D000336:Aerosols; D000512:Alpha Particles; D000818:Animals; D008168:Lung / Q000378:metabolism / Q000528:radiation effects*; D008433:Mathematics; D008954:Models, Biological; D011005:Plutonium / Q000008:administration & dosage* / Q000378:metabolism; D051381:Rats
chemical_list: D000336:Aerosols; C026885:plutonium dioxide; D011005:Plutonium
vernacular_title: Radiobiologicheskoe deĭstvie al'fa-izluchaiushchikh nuklidov, inkorporirovannykh v legkie. Mikroraspredelenie radioaktivnogo veshchestva i problema radiatsionnoĭ zashchity.