Internal hydrocephalus, optic nerve aplasia, and microphthalmia in CPB-WE (Wezob) and Cpb:WU (Wistar) rats.
Wistar rats of the inbred CPB-WE and the random bred Cpb:WU strains have been used in neuroanatomical studies. In both groups of rats a high incidence of hydrocephalus was observed. In the CPB-WE rats the ventricular dilatation was accompanied by optic tract lesions and microphthalmia. The present report describes the gross and microscopic findings in these rats and discusses the possible aetiology.
D000818:Animals; D006849:Hydrocephalus / Q000473:pathology / Q000662:veterinary*; D008850:Microphthalmos / Q000473:pathology / Q000662:veterinary*; D009901:Optic Nerve Diseases / Q000473:pathology / Q000662:veterinary*; D051381:Rats; D011919:Rats, Inbred Strains