[Effectiveness of measles immunoprophylaxis and the criteria for assessing its possible elimination].
The study of measles morbidity in Donetsk Province in 1960-1984 and the study of antimeasles immunity in different groups of the population have shown that the problem of the liquidation of measles cannot be solved by immunizing the population in a single administration of the vaccine. To enhance the effectiveness of the immunoprophylaxis of measles and its influence on the epidemic process, a number of problems must be solved with the aim to improve the quality of the vaccine, especially its thermal stability, to establish the possibility of shifting the beginning of immunization from 15-17 months to 12 months of age, to increase the coverage of children with immunization against measles by decreasing the number of groundless exemptions from immunization and by immunizing children in risk groups according to individual schedules and dosage, to carry out selectively the booster immunization of persons who have lost their postvaccinal immunity, as revealed by laboratory test, or in whom such loss may be supposed, to introduce the objective method (indirect hemagglutination test) for controlling the state of immunity among different groups of the population into laboratory practice at sanitary and epidemiological stations. As to the possibility of the liquidation of measles, the statement of this problem is correct, but for its solution a complex of additional prophylactic and epidemic-control measures should be taken.
D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis; D004197:Disease Reservoirs; D005260:Female; D006801:Humans; D007109:Immunity; D007117:Immunization, Secondary; D007223:Infant; D007231:Infant, Newborn; D008457:Measles / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D008458:Measles Vaccine / Q000276:immunology*; D008459:Measles virus / Q000276:immunology; D049590:Postpartum Period; D011247:Pregnancy; D014455:Ukraine
D000914:Antibodies, Viral; D008458:Measles Vaccine
Effektivnost' immunoprofilaktiki kori i kriterii otsenki vozmozhnosti ee likvidatsii.