Coronary intima: the phylogenetic approach to appearance of lesions.
In the course of phylogenetic evolution the coronary artery intima undergoes changes in the composition of the ground substance (from hyaluronic acid-like substances to sulphate ones) and a relative increase of the intimal thickness. A correlation was found between these changes and the increasing propensity for coronary atherosclerotic lesions.
D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology*; D003331:Coronary Vessels / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D010802:Phylogeny; D013045:Species Specificity