title: Progressive supranuclear palsy: report of a case with torticollis, blepharospasm, and dysfluency.
abstract: A 76-year-old man is reported with advanced progressive supranuclear palsy (PSP) who developed a persistent, gradually progressive torticollis over a period of several months. Blepharospasm and dysfluency of the extrapyramidal type antedated the torticollis. This first report of torticollis in PSP reinforces previous notions that torticollis is related to pathologic changes in the striatum and brainstem. In addition, the combination of torticollis and blepharospasm in our patient supports the previous concept that these two "focal dystonias" have a common pathophysiologic mechanism. This also suggests that dysfluency in PSP may be an expression of a focal dystonia involving the muscles of articulation.
mesh_terms: D000368:Aged; D001764:Blepharospasm / Q000209:etiology*; D005141:Eyelid Diseases / Q000209:etiology*; D006801:Humans; D008297:Male; D013342:Stuttering / Q000209:etiology*; D013494:Supranuclear Palsy, Progressive / Q000150:complications*; D014103:Torticollis / Q000209:etiology*