title: [Neuroblastoma; biology and prognostic factors].
abstract: Recently accumulated data on the biology of the tumors of neuroblastoma group are reviewed. Histopathological classification system developed by Shimada et al, elevated levels of serum neuron-specific enolase and ferritin, and gene abnormalities including partial deletion of the short arm of chromosome #1 and N-myc gene amplification are discussed as well as their prognostic significance. Also, the current activities of CCSG (Childrens Cancer Study Group) neuroblastoma studies are briefly reported.
mesh_terms: D002648:Child; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002878:Chromosomes, Human, Pair 1; D005293:Ferritins / Q000097:blood; D005784:Gene Amplification; D006801:Humans; D009447:Neuroblastoma / Q000145:classification* / Q000235:genetics / Q000401:mortality; D010751:Phosphopyruvate Hydratase / Q000097:blood; D011379:Prognosis
chemical_list: D005293:Ferritins; D010751:Phosphopyruvate Hydratase