Hairy cell leukemia and mucormycosis. Treatment with alpha-2 interferon.
Right maxillary sinus mucormycosis developed in a 45-year-old patient with hairy cell leukemia and pancytopenia. The patient recovered with surgical debridement, amphotericin therapy, and institution of alpha-2 interferon as therapy for his hairy cell leukemia. This may be the first case of the use of alpha-2-interferon therapy in a patient with documented systemic fungal infection and hairy cell leukemia and a rare example of recovery from this infection in a hematologic malignancy.
D000666:Amphotericin B / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000150:complications* / Q000628:therapy; D008297:Male; D008443:Maxillary Sinus; D008875:Middle Aged; D009091:Mucormycosis / Q000628:therapy; D010198:Pancytopenia / Q000150:complications; D012852:Sinusitis / Q000209:etiology* / Q000628:therapy
D007370:Interferon Type I; D000666:Amphotericin B