Mycosis fungoides associated with dystrophic xanthomatosis.
A 59-year-old man with no evidence or history of hyperlipidemia had a dystrophic xanthoma, an accumulation of lipid-rich foam cells in an area of damaged or abnormal skin, that was associated with untreated mycosis fungoides (MF). The patient was subsequently treated with whole-body electron beam therapy. This association of MF and dystrophic xanthoma illustrates histiocyte and xanthoma cell interaction in MF, a cutaneous T-cell lymphoma. Xanthomas may be a cutaneous sign of an underlying lymphoproliferative or myeloproliferative disease in normolipemic patients.
D006801:Humans; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000150:complications* / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D014973:Xanthomatosis / Q000150:complications* / Q000473:pathology