Neuropeptide Y immunoreactivity in human cerebrospinal fluid.
Neuropeptide Y (NPY) immunoreactivity has been determined in human cerebrospinal fluid (CSF). High pressure liquid chromatography revealed that the NPY immunoreactivity co-eluted with authentic NPY. The range of NPY levels was 108 +/- 18 pg/ml (mean +/- S.D.) in a group of 28 normal subjects. In five additional subjects NPY immunoreactivity was measured in 4 sequential 8 ml aliquots of CSF to determine whether a rostro-caudal gradient was present. No significant differences in NPY levels were detected between any of the 4 aliquots.
D000375:Aging; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D007106:Immune Sera; D008297:Male; D009478:Neuropeptide Y / Q000134:cerebrospinal fluid* / Q000302:isolation & purification; D012016:Reference Values
D007106:Immune Sera; D009478:Neuropeptide Y