title: Levels and trends of chlorinated hydrocarbon contaminants in the breast milk of Canadian women.
abstract: A total of 210 breast milk samples from 5 different regions across Canada were analyzed for polychlorinated biphenyls (PCBs), hexachloro-1,3-butadiene, ten chlorinated benzenes, two chlorinated naphthalenes, Mirex, photomirex, alpha, beta and gamma hexachlorocyclohexane, alpha and gamma chlordane, oxychlordane, trans-nonachlor, p,p'-DDT and some analogs, heptachlor epoxide, dieldrin and octachlorostyrene. There was no evidence for the presence of hexachloro-1,3-butadiene, Mirex, octachlorostyrene, chlorinated naphthalenes or tetrachlorobenzenes in the breast milk. Residues of other compounds were found in all samples, except 1,2-dichlorobenzene, gamma hexachlorocyclohexane, alpha and gamma chlordane and p,p'-TDE, which were less frequently observed, while o,p'-DDT was only found in approximately one quarter of all samples. Since 1967, a steady decline in heptachlor epoxide, dieldrin and p,p'-DDT and related residues is apparent. At the same time however, there is an apparent increase in PCB residue levels since 1970. This apparent increase should be viewed with some caution, since much of this increase might be attributed to better sampling and analytical techniques. Residue levels of breast milk in Canada were similar to those found in other industrial nations. Regional differences in residue levels appeared to be minimal.
mesh_terms: D002170:Canada; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D008895:Milk, Human / Q000032:analysis*; D011247:Pregnancy
chemical_list: D006843:Hydrocarbons, Chlorinated