Two cytochrome oxygen consumption model and mechanism for carotid body chemoreception.
We have measured sinus nerve discharge, tissue PO2 and oxygen consumption (VO2) in cat carotid bodies under different experimental conditions using our recessed oxygen microelectrode. Our results indicate that the change in chemoreceptor activity with oxygen disappearance following blood flow occlusion can be related to a two cytochrome model for oxygen consumption as previously proposed by Mills and Jöbsis (1972).
D000818:Animals; D002344:Carotid Body / Q000502:physiology*; D002415:Cats; D002628:Chemoreceptor Cells / Q000502:physiology*; D003580:Cytochromes / Q000378:metabolism*; D007700:Kinetics; D008433:Mathematics; D008959:Models, Neurological; D010101:Oxygen Consumption
D003580:Cytochromes