Blood flow to the respiratory and limb muscles and to abdominal organs during maximal exertion in ponies.
Using radionuclide-labelled microspheres, 15 micron in diameter, we studied blood flow in the respiratory muscles (diaphragm and intercostal muscles), abdominal organs (adrenal glands, kidneys, pancreas, spleen and the small and large intestines), muscles of propulsion (gluteus medius and biceps femoris), and other working (triceps brachii and longissimus dorsi lumborum) and non-working (temporal and masseter) muscles of ponies at rest and during maximal exercise performed on a treadmill. During maximal exercise heart rate, whole body O2 consumption, cardiac output and mean aortic pressure increased 4.4-fold, 38-fold, 8-fold and 1.5-fold of their resting values, respectively. During maximal exertion arterial CO2 tension and arterial pH decreased while arterial O2 content increased by 58% due to a 59.6% rise in haemoglobin concentration. Arterial O2 tension decreased somewhat and the calculated alveolar to arterial O2 tension gradient widened during exertion. During maximal exertion blood flow in the adrenal glands increased while that in the kidneys, spleen, pancreas, small intestine and colon decreased precipitously. Thus ponies exhibited intense vasoconstriction in the renal and splanchnic vascular beds, similar to that reported in man but not in exercising dogs. During maximal exertion stride (and hence respiratory) frequency of galloping ponies was 138 +/- 3 min-1, and the blood flow and O2 delivery in the diaphragm were not different from those in other strenuously working muscles, namely gluteus medius, biceps femoris (muscles of propulsion) and triceps brachii. Blood flow in the intercostal muscles was only 54% of that in the diaphragm at rest, but with maximal exercise it registered a marked increment and the perfusion became similar to that in the longissimus dorsi lumborum, a powerful extensor of the back and loins.
D000005:Abdomen / Q000098:blood supply*; D000818:Animals; D005552:Forelimb / Q000502:physiology; D006439:Hemodynamics; D006614:Hindlimb / Q000502:physiology; D006736:Horses / Q000502:physiology*; D009132:Muscles / Q000098:blood supply*; D010100:Oxygen / Q000097:blood; D005082:Physical Exertion; D012039:Regional Blood Flow; D012132:Respiratory Muscles / Q000098:blood supply*
D010100:Oxygen