title: Sea-blue histiocyte syndrome with cutaneous involvement. Case report with ultrastructural findings.
abstract: A patient with infiltration of the skin resulting in eyelid swelling and facial nodules was recognized as a case of sea-blue histiocyte syndrome with cutaneous involvement. Typical sea-blue histiocytes were found in the skin and confirmation was provided by electron microscopy. Hepatosplenomegaly, lung infiltrates and bone marrow involvement were the other symptoms. The relationship between sea-blue histiocyte syndrome and adult Niemann-Pick disease is also discussed.
mesh_terms: D000328:Adult; D005145:Face / Q000002:abnormalities; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009542:Niemann-Pick Diseases / Q000150:complications; D012618:Sea-Blue Histiocyte Syndrome / Q000150:complications*; D012867:Skin / Q000648:ultrastructure; D012871:Skin Diseases / Q000150:complications*