The functional activities of the pigment epithelium in aging.
The phagocytic ability of the pigment cells of the retinae of mice of different ages was studied in 2-, 5-, 7-, and 9-month-old animals. A decrease in activity was evident as the animals aged. There was also a difference in the response pattern of enzymes (as demonstrated in the case of alkaline phosphatase) in the first 35 h after latex bead injection.
D000375:Aging; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D006651:Histocytochemistry; D051379:Mice; D008813:Mice, Inbred ICR; D008863:Microspheres; D010587:Phagocytosis; D010857:Pigment Epithelium of Eye / Q000201:enzymology / Q000502:physiology*
D000469:Alkaline Phosphatase