Marjolin's ulcer complicating a pressure ulcer: case report and literature review.
Fifteen years after spinal cord injury and 14 years after development of a sacral pressure ulcer in a paraplegic man, a squamous cell carcinoma was found on biopsy during surgical reconstruction of the pressure ulcer. The patient refused the extensive surgery necessary to remove the infiltrating tumor, and the wound was closed with a latissimus dorsi flap. Pressure ulcers remain a problem in spinal cord injured and other disabled patients. Malignant degeneration (Marjolin's ulcer) in chronic pressure ulcers and other chronic skin ulcerations may become more widespread as the life span of spinal cord injured patients increases.
D000328:Adult; D002081:Buttocks; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008297:Male; D003668:Pressure Ulcer / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D013119:Spinal Cord Injuries / Q000150:complications; D013997:Time Factors