Accuracy of Apgar score and arterial cord-blood pH in diagnosis of perinatal brain-damage assessed by CK-BB isoenzyme measurement.
This study was carried out on 45 newborns to evaluate the accuracy of 1 minute Apgar score and umbilical arterial pH for prediction of the risk of perinatal brain damage. Using a new and very sensitive method for CK-BB determination, which is considered a good indicator of brain damage, CK-BB was used as reference. Patients with low Apgar score at one minute of life had significantly higher cord blood CK-BB values than the control group (p less than 0.01). No difference was found between the control group and the group with umbilical cord blood acidosis (p less than 0.2).
D001034:Apgar Score; D001238:Asphyxia Neonatorum / Q000150:complications; D001925:Brain Damage, Chronic / Q000175:diagnosis* / Q000201:enzymology / Q000209:etiology; D003402:Creatine Kinase / Q000097:blood*; D005312:Fetal Blood / Q000201:enzymology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007527:Isoenzymes; D011379:Prognosis
D007527:Isoenzymes; D003402:Creatine Kinase