Decreased amniotic fluid magnesium concentration in diabetic pregnancy.
Amniotic fluid samples from 21 diabetic pregnant women were pair-matched for gestational age with 21 samples obtained from nondiabetic women, and analyzed for magnesium concentration. Mean +/- standard deviation amniotic fluid magnesium concentration (mg/dL) was 0.86 +/- 0.21 in the diabetic group and 1.06 +/- 0.22 in the control group (P less than .001). It is concluded that in the diabetic pregnancy, a state of fetal magnesium deficiency exists. This deficient state may contribute to neonatal hypocalcemia in infants of diabetic mothers.
D000653:Amniotic Fluid / Q000032:analysis*; D003404:Creatinine / Q000032:analysis; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008274:Magnesium / Q000032:analysis*; D008275:Magnesium Deficiency / Q000097:blood; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000378:metabolism*; D013054:Spectrophotometry, Atomic
D003404:Creatinine; D008274:Magnesium