An improved morphological technique for the study of cochleotoxicity in guinea pigs.
Scanning electron microscopy is commonly used to study the normal or pathologically altered cochlear epithelium. It is especially useful for the study of ototoxicity in humans or animals. A cochlear microdissection technique in the guinea pig is presented which permits examination of the whole membranous cochlea with little artefactual damage to the sensory structures under study.
D000818:Animals; D004210:Dissection / Q000379:methods*; D006168:Guinea Pigs; D007612:Kanamycin / Q000494:pharmacology; D008855:Microscopy, Electron, Scanning; D009925:Organ of Corti / Q000187:drug effects / Q000648:ultrastructure*
D007612:Kanamycin