Microcolonies of hemopoietic cells in the rat choroid plexus during the neonatal period.
Microcolonies of hemopoietic cells have occasionally been found in the choroidal stroma of the rat myelencephalic choroid plexus during neonatal life. These hemopoietic foci are mixed colonies mainly composed of erythroblasts and maturing megakaryocytes; granulocyte precursors were not identified. The morphological data indicate that both erythro- and magakaryopoiesis occur in these microcolonies. With respect to their origin, we suggest that circulating pluripotential stem cells may colonize the choroidal stroma and produce erythro- and megakaryocyte cell lines.
D000818:Animals; D000831:Animals, Newborn / Q000033:anatomy & histology*; D002831:Choroid Plexus / Q000166:cytology*; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains