Universal regularities in protein primary structure: preference in bonding and periodicity.
Utilizing the whole protein data base as well as parts of it (groups and individual representatives), the universal character of the regularities in protein primary structure - preference in bonding (self-ordering) and periodicity - is shown by means of an improved procedure of checking statistical significance. In the vast majority of the cases there is a preference in bonding with the same or with very similar amino acid. Taken as a whole, both regularities show a universal character. The results obtained provide evidence in favour of the conception about the priority of proteins as information polymers.
D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D006860:Hydrogen Bonding; D011506:Proteins / Q000235:genetics*; D013329:Structure-Activity Relationship
D011506:Proteins