[Determination of the genetic toxicity of 5-nitrofurylacrylic acid].
5-Nitro-2-furylacrylic acid besides gene mutations exerts positive effects in two other tests: it induces sister chromatid exchange in hamster cells V79 and cell transformation in vitro. All the presented data concerning mutagenicity of this compound have permitted concluding that this acid cannot be recommended for use as a stabilizer of wines and other beverages.
D000179:Acrylates / Q000633:toxicity*; D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D006224:Cricetinae; D003412:Cricetulus; D004912:Erythrocytes / Q000187:drug effects; D005260:Female; D005503:Food Additives / Q000633:toxicity*; D008297:Male; D051379:Mice; D009152:Mutagenicity Tests; D009581:Nitrofurans / Q000633:toxicity*; D012854:Sister Chromatid Exchange / Q000187:drug effects
D000179:Acrylates; D005503:Food Additives; D009581:Nitrofurans; C222012:nitrofurylacrylic acid
Opredelenie genotoksichnosti 5-nitrofurilakrilovoĭ kisloty.