Irritation, sensitization, photoirritation and photosensitization assays with a glyphosate herbicide.
Glyphosate, a widely utilized herbicide, was evaluated for acute irritation, cumulative irritation, photoirritation and allergic and photoallergic contact potential in 346 volunteers. The herbicide was less irritant than a standard liquid dishwashing detergent and a general all purpose cleaner. There was no evidence for the induction of photoirritation, allergic or photoallergic contact dermatitis. 10% glyphosate in water is proposed as a diagnostic patch test concentration.
D000328:Adult; D000368:Aged; D005260:Female; D005998:Glycine / Q000031:analogs & derivatives* / Q000633:toxicity; D006540:Herbicides / Q000633:toxicity*; D006801:Humans; D007509:Irritants; D008297:Male; D008875:Middle Aged; D010328:Patch Tests / Q000379:methods; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D000097797:Glyphosate
D005998:Glycine; D006540:Herbicides; D007509:Irritants; D000097797:Glyphosate