title: Plasma and liver amino acids in rats after administration of ethanol or acetaldehyde.
abstract: The changes in the level and pattern of free amino acids in plasma and liver after ethanol or acetaldehyde intoxication has been investigated in rats. After administration of 30% (w/v) ethanol, 6 g kg-1, or 1.5% (w/v) acetaldehyde, 0.3 ml kg-1, for 4 weeks we found a decrease in plasma and liver branched-chain amino acids and an increase in plasma aromatic amino acids and methionine. The results are analogous to those found in studies of damaged liver.
mesh_terms: D000079:Acetaldehyde / Q000494:pharmacology*; D000596:Amino Acids / Q000097:blood / Q000378:metabolism*; D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000596:Amino Acids; D000431:Ethanol; D000079:Acetaldehyde