Management of rachitic deformities in children with chronic renal failure.
Five children with chronic renal failure and severe rachitic deformities of the lower limbs were treated with 1 alpha-hydroxyvitamin D (1 alpha-OHD3) for 16 to 53 months. There was symptomatic, biochemical and radiological improvement in all five children and operative correction of their deformities was not needed. We recommend a trial of treatment with 1 alpha-OHD3 for this condition before surgical procedures.
D000536:Aluminum Hydroxide / Q000627:therapeutic use; D002119:Calcium Carbonate / Q000627:therapeutic use; D002648:Child; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000000981:diagnostic imaging / Q000188:drug therapy*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use; D007223:Infant; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D011859:Radiography; D013997:Time Factors
D006887:Hydroxycholecalciferols; D000536:Aluminum Hydroxide; D002119:Calcium Carbonate; C008088:alfacalcidol