Assessment of fiber strength in a urinary bladder by using experimental pressure volume curves: an analytical method.
In the present study, an analytical method is developed to deduce the constitutive equations of fibers embedded in a thick shell from the time-variant pressure volume curves obtained by experimental procedures. It is assumed that the spherical shell under consideration is composed of a fiber reinforced material and undergoes radial deflection, modeling the behavior of some biological shells such as urinary bladder. The fiber stress is expressed as a function of fiber strain, rate of strain and the degree of biochemical activation. The function form is chosen such that equations of mechanical equilibrium can be integrated analytically to yield chamber pressure as a function of chamber volume, time rate of change of volume and activation. Arbitrary coefficients appearing in the fiber stress-equation are also present in the resultant time-variant pressure-volume relation. These coefficients can be determined by curve-fitting commonly used clinical data such as cystometry measurements.
D000818:Animals; D001696:Biomechanical Phenomena; D004285:Dogs; D006874:Hydrostatic Pressure; D066298:In Vitro Techniques; D008954:Models, Biological; D009119:Muscle Contraction; D009130:Muscle, Smooth / Q000502:physiology; D013314:Stress, Mechanical; D013718:Tensile Strength; D001743:Urinary Bladder / Q000033:anatomy & histology / Q000502:physiology*