IgE synthesis in vitro: attempt to isolate stimulating factors.
Studies made in our laboratory have demonstrated the presence in atopic serum of enhancing factors(s) for in vitro IgE synthesis by peripheral blood lymphocytes (BPL). Here we show that these enhancing factors can be recovered from human serum by means of immunoabsorbents. This factor is able to stimulate in vitro IgE synthesis by PBL independent of presence of IgE.
D002846:Chromatography, Affinity; D006801:Humans; D006967:Hypersensitivity / Q000097:blood*; D007073:Immunoglobulin E / Q000096:biosynthesis*; D008214:Lymphocytes / Q000378:metabolism; D008222:Lymphokines / Q000097:blood*; D029584:Prostatic Secretory Proteins
D008222:Lymphokines; D029584:Prostatic Secretory Proteins; C043076:beta-microseminoprotein; C013059:immunoglobulin-binding factors; D007073:Immunoglobulin E