Isolation of Clostridium difficile from various colonies of laboratory mice.
An attempt was made to isolate Clostridium difficile from a total of 565 mice from nine different conventional mouse colonies and six different specified-pathogen-free mouse colonies. C. difficile was isolated from all the conventional colonies but from none of the specified-pathogen-free colonies. Ampicillin injected intraperitoneally increased the isolation rate of C. difficile from mouse faeces to 63.6% compared with 19.4% from untreated mice.
D000818:Animals; D000830:Animals, Laboratory / Q000382:microbiology*; D003013:Clostridium / Q000302:isolation & purification*; D051379:Mice / Q000382:microbiology*; D013045:Species Specificity