Circadian rhythm of blood and urinary copper in presumably healthy subjects of vegetarian food habit.
Circadian rhythm of blood and urinary copper has been studied in presumably healthy subjects of a particular ethnic group in India who are vegetarians. A definite 24-hr variation has been observed for both blood and urinary copper. The peak for blood copper was 1,500 hr and the lowest value was 0600 hr, with values of 0.185 mg/100 ml and 0.106 mg/100 ml respectively. The urinary peak and trough occurred at 0600 and 0300 hr, respectively. Remarkably higher 24-hr copper excretion values were noted (64.49 micrograms/day) with a range of 15-100 micrograms/day. The blood level of copper (0.134 mg/100 ml) remained within the range reported. One subject out of 25 deviated from the group with respect to circadian phasing and amplitude to urinary copper excretion.
D002940:Circadian Rhythm; D003300:Copper / Q000097:blood* / Q000652:urine; D014676:Diet, Vegetarian; D005006:Ethnicity; D006801:Humans; D007194:India
D003300:Copper