title: High serum bile acid level in obesity: its decrease during and after total fasting.
abstract: Elevated serum bile acid levels were observed in overweight subjects as compared to those with an ideal weight. Fasting for 14 days resulted in a gradual decrease to the normal level of serum cholic, chenodeoxycholic and deoxycholic acid concentrations. There was no change in the serum bile acid level during a two days refeeding period. The findings suggest that, in addition to the beneficial weight reduction, normalization of bile acid homeostasis can be achieved by fasting in obesity.
mesh_terms: D000328:Adult; D001647:Bile Acids and Salts / Q000096:biosynthesis / Q000097:blood*; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000503:physiopathology / Q000628:therapy
chemical_list: D001647:Bile Acids and Salts