title: [High-dose heparin in a patient with purpura fulminans following varicella].
abstract: We report on a 3 1/2 year old girl with purpura fulminans after varicella who made a complete recovery on treatment with an appropriate high-dose heparin regimen and other supporting measures. Several attempts to reduce the heparin dosage from the initial high level (85 IU/kg/hour) to the usual level (25 IU/kg/hour) were followed each time by an immediate deterioration in the clinical condition.
mesh_terms: D001780:Blood Coagulation Tests; D002644:Chickenpox / Q000150:complications*; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D005260:Female; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D011693:Purpura / Q000188:drug therapy*
chemical_list: D006493:Heparin
vernacular_title: Hoher Heparinbedarf bei einer Patientin mit Purpura fulminans nach Varicellen.