[Distribution of oxygen tension in the brain of spontaneously hypertensive rats].
The distribution of cerebral tissue pO2 in spontaneously hypertensive Okamoto-Aoki rats (SHR) and normotensive Wistar-Kyoto rats (WK) was studied by means of polarographic microelectrodes 1-3 microns in diameter. SHR exhibited pO2 shifts towards low values and an increased heterogeneity of pO2 distribution in the cerebral tissue. Morphological studies of the brain have revealed diffuse and focal ischemia in the grey and white matter of the brain in SHR.
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D002545:Brain Ischemia / Q000503:physiopathology; D008839:Microelectrodes; D010101:Oxygen Consumption; D010313:Partial Pressure; D011048:Polarography; D051381:Rats; D011918:Rats, Inbred SHR / Q000378:metabolism*; D011919:Rats, Inbred Strains / Q000378:metabolism*; D011921:Rats, Inbred WKY
Raspredelenie napriazheniia kisloroda v mozge spontanno gipertenzivnykh krys.