[Behavior of the nucleolus organizer regions of the chromosomes in polykaryocytes consisting of micronuclei].
The nucleolar organizer regions (NORs) of Chinese hamster chromosomes (clone 237, cell line BIId-ii-FAF28) were studied in mononuclear cells and polykaryocytes induced with colcemid. The chromosomes with NORs were marked as 1, 2, 3, 4. The activity of NORs in mononuclear cells was higher in chromosomes 1, 2, 3. The associations of NORs were observed between chromosomes I and 2 (3% of all metaphases). In polykaryocytes the chromosomal pairs 1, 2, 3 showed different NOR activity in different metaphases. The associations of NORs in pairs of chromosome I were found in 51.3% of cases. The associations of NORs in pairs of chromosome 2 were observed in 7.5% of cases. This method may be used for the estimation of association potency of NORs in chromosomes.
D000818:Animals; D002460:Cell Line; D002871:Chromosome Banding / Q000379:methods; D002999:Clone Cells / Q000187:drug effects / Q000648:ultrastructure; D006224:Cricetinae; D003412:Cricetulus; D003703:Demecolcine / Q000494:pharmacology; D008677:Metaphase / Q000187:drug effects; D009697:Nucleolus Organizer Region / Q000187:drug effects / Q000648:ultrastructure*
D003703:Demecolcine
Povedenie iadryshkoobrazuiushchikh raĭonov khromosom v polikariotsitakh, sostoiashchikh iz mikroiader.