Do asparagine-linked carbohydrate chains in glycoproteins have a preference for beta-bends?
X-ray structures of the conformation of carbohydrate moieties and connected regions of glycoproteins are summarized. Evidence is presented that there is some preference for carbohydrate attachment at beta-bends. Evolution may have favored glycosylation to occur at bends to ensure free mobility of the carbohydrate moieties.
D000818:Animals; D006023:Glycoproteins; D006031:Glycosylation; D006801:Humans; D008968:Molecular Conformation; D011487:Protein Conformation
D006023:Glycoproteins