Disseminated cutaneous leishmaniasis in a field clinic in Bahia, Brazil: a report of eight cases.
Eight Bahian patients with cutaneous leishmaniasis who had 20 or more ulcerative lesions of short duration are described. Of five identifications of isolated parasites, four were Leishmania braziliensis braziliensis and one was L. mexicana amazonensis. All but one had positive Montenegro tests initially, and all did after treatment. All had circulating anti-leishmanial antibodies and five responded well to glucantime therapy suggesting a functioning immune response. This is quite different to the anergic hansenoid leishmaniasis seen with L. mexicana amazonensis infections in Brazil. Possible reasons for the occurrence of this type of leishmaniasis are briefly discussed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000965:Antimony / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001938:Brazil; D006801:Humans; D007896:Leishmaniasis / Q000188:drug therapy / Q000473:pathology*; D007897:Leishmaniasis, Mucocutaneous / Q000188:drug therapy / Q000473:pathology; D008536:Meglumine; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000965:Antimony