Limitations in localising and killing tumours using radiolabelled antibodies.
Radiolabelled antibodies against tumours are being studied intensely for their use in tumour detection and tumour destruction. Although a host of different tumour types can be localised, results at present are no better than other scanning techniques. In addition no tumour has been eradicated using labelled antibodies. Dramatic improvements will depend upon a fuller understanding of tumour cell biology and optimising all the parameters involved.
D000912:Antibodies, Neoplasm / Q000276:immunology*; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D011868:Radioisotopes / Q000627:therapeutic use; D011877:Radionuclide Imaging
D000912:Antibodies, Neoplasm; D011868:Radioisotopes