title: [Human lactoferrin: isolation of highly purified preparations from human milk, various physico-chemical properties and distribution in normal and tumor tissues].
abstract: Two procedures for isolation of lactoferrin are described using ion exchange and immunoaffinity chromatography. Electrophoretic mobility, molecular mass, isoelectric point and other physico-chemical properties of the antigen were studied. Immunodiffusion and immunoperoxidase techniques exhibited presence of the antigen in some tissues containing glandular epithelium as well as a decrease in lactoferrin content in malignization.
mesh_terms: D002846:Chromatography, Affinity; D005260:Female; D006801:Humans; D007525:Isoelectric Focusing; D007781:Lactoferrin / Q000032:analysis / Q000302:isolation & purification*; D007782:Lactoglobulins / Q000302:isolation & purification*; D008895:Milk, Human / Q000032:analysis*; D009369:Neoplasms / Q000032:analysis*; D014018:Tissue Distribution
chemical_list: D007782:Lactoglobulins; D007781:Lactoferrin
vernacular_title: Laktoferrin cheloveka: poluchenie vysokoochishchennykh preparatov iz moloka zhenshchin, nekotorye fiziko-khimicheskie svoĭstva i raspredelenie v normal'nykh i opukholevykh tkaniakh.