Radiological rickets in extremely low birthweight infants.
Forty-eight infants of birthweight less than 1000 g who survived for more than 28 days, had wrist X-rays to prospectively determine the incidence of radiological rickets. Twelve infants (25%) had normal X-rays throughout, 10 infants (21%) showed osteopenia and 26 infants (54%) had classical changes of rickets of which 8 (17% of the total) had spontaneous fractures. There was poor correlation between peak values of serum alkaline phosphatase and the radiological changes.
D000469:Alkaline Phosphatase / Q000097:blood; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood / Q000000981:diagnostic imaging* / Q000473:pathology; D011446:Prospective Studies; D011859:Radiography; D012279:Rickets / Q000097:blood / Q000000981:diagnostic imaging* / Q000473:pathology; D014955:Wrist Joint / Q000000981:diagnostic imaging / Q000473:pathology
D000469:Alkaline Phosphatase