Major and modified nucleosides as markers in ovarian cancer: a pilot study.
A number of major and modified nucleosides were measured in urine samples of patients with ovarian cancer. The patients were divided into three groups based on histological criteria: benign, borderline, malignant. 44% of the measured marker levels of the benign group were in the normal range, whereas 97% of the borderline and malignant groups were outside the normal range. After a total hysterectomy with adnexectomy and omentectomy in a patient with a borderline type malignancy, six of the seven elevated markers decreased to normal values.
D000328:Adult; D000368:Aged; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D008875:Middle Aged; D009705:Nucleosides / Q000652:urine*; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000652:urine*
D009705:Nucleosides