title: Avoidance of maternal morbidity in acute intrauterine infection following chorionic villus sampling.
abstract: Serious maternal morbidity has been a feature of the few documented cases of acute intrauterine infection after chorionic villus sampling. A case is described in which infection manifested 14 days after transcervical chorion biopsy. Broad-spectrum antibiotics were begun, and ultrasound demonstrated a live fetus. After vacuum curettage was performed, repeat scan showed an empty uterus. Anaerobes isolated from the cervix both before chorionic villus sampling and during the infection were also implicated in published reports of patients developing life-threatening complications, but were not treated specifically until after morbid sequelae had occurred. Serious morbidity was avoided in this patient by aggressive management with early anaerobic cover, uterine evacuation despite the presence of a live fetus, and confirmation of complete evacuation by ultrasound.
mesh_terms: D000032:Abortion, Therapeutic; D000208:Acute Disease; D001424:Bacterial Infections / Q000188:drug therapy / Q000209:etiology*; D001706:Biopsy / Q000009:adverse effects; D002824:Chorionic Villi / Q000473:pathology*; D005260:Female; D006801:Humans; D011247:Pregnancy; D014591:Uterine Diseases / Q000188:drug therapy / Q000209:etiology*