Fluoride treatment in corticosteroid induced osteoporosis.
Severe osteoporosis with multiple vertebral fractures occurred in two girls receiving prolonged high dose corticosteroids for relapsing dermatomyositis. Sodium fluoride, supplemented with calcium and vitamin D, helped control secondary osteoporosis in one case and should be considered as part of the curative treatment of corticoid induced osteoporosis.
D002648:Child; D003882:Dermatomyositis / Q000188:drug therapy; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D010024:Osteoporosis / Q000139:chemically induced / Q000188:drug therapy*; D012969:Sodium Fluoride / Q000627:therapeutic use*
D005938:Glucocorticoids; D012969:Sodium Fluoride