Identification of disulfide bonds in carboxy-terminal propeptides of human type I procollagen.
Intra-chain and inter-chain disulfide bonds within the carboxy-terminal propeptides of human type I procollagen were studied using cyanogen bromide cleavage of the propeptides and electrophoresis on SDS-polyacrylamide/glycerol gels. The results could provide a better understanding of the assembly of pro alpha-chains into procollagen.
D003488:Cyanogen Bromide; D004220:Disulfides / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D010446:Peptide Fragments / Q000032:analysis; D011347:Procollagen
D004220:Disulfides; D010446:Peptide Fragments; D011347:Procollagen; D003488:Cyanogen Bromide