Incidence, risk factors, and morphology in operating microscope light retinopathy.
A review of 135 consecutive cataract operations identified ten cases (7.4%) of operating microscope light retinopathy. Ophthalmoscopically, these light retinopathy lesions appeared as a focal pigment epithelial change with varying degrees of pigment clumping in the center. Fluorescein angiography accentuated the lesion by demonstrating a sharply demarcated transmission defect, occasionally with multiple satellite lesions. The shape of the lesion matched the shape of the illuminating source of the particular operating microscope used during the surgery. The most significant risk factor associated with the production of these light retinopathy lesions was prolonged operating time. Mean total operating time for the ten patients with light retinopathy was 51 minutes longer than for those without (P less than .0001). Other significant associated factors were the presence of diabetes mellitus (P less than .03), younger age (P less than .05), and the use of hydrochlorothiazide (P less than .04).
D002387:Cataract Extraction / Q000009:adverse effects / Q000379:methods; D048909:Diabetes Complications; D005451:Fluorescein Angiography; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects; D007049:Iatrogenic Disease; D007432:Intraoperative Period; D008027:Light / Q000009:adverse effects*; D008853:Microscopy / Q000379:methods*; D009887:Ophthalmoscopy; D011832:Radiation Injuries; D012164:Retinal Diseases / Q000139:chemically induced / Q000209:etiology* / Q000473:pathology; D012306:Risk; D013997:Time Factors
D006852:Hydrochlorothiazide