Novel polyether antibiotics X-14873A, G and H produced by a Streptomyces: taxonomy of the producing culture, fermentation, biological and ionophorous properties of the antibiotics.
Novel polyether antibiotics X-14873A, X-14873G, and X-14873H are produced by the fermentation of Streptomyces sp. X-14873 (ATCC 31679). This report presents taxonomic studies and fermentation conditions for the antibiotic producing culture. The antibiotics are mainly active against Gram-positive bacteria. The ionophore properties of X-14873A are also characterized.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005285:Fermentation; D005663:Furans / Q000378:metabolism / Q000494:pharmacology; D007476:Ionophores / Q000494:pharmacology*; D012417:Rumen / Q000378:metabolism; D013302:Streptomyces / Q000145:classification / Q000378:metabolism*; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D005663:Furans; D007476:Ionophores; C051494:antibiotic X 14873G; C051492:antibiotic X 14873H; C051493:antibiotic X 14873A