Halothane-associated liver damage and renal failure in a young child.
A case of halothane-associated liver damage and renal failure is described in an 18-month-old girl after her third halothane anaesthetic. There had been two uneventful enflurane anaesthetics. The diagnosis was confirmed by detecting antibodies specific for halothane-associated liver failure using a recently developed enzyme-linked immunosorbent assay.
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000410:Alanine Transaminase / Q000097:blood; D000758:Anesthesia; D001219:Aspartate Aminotransferases / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003404:Creatinine / Q000097:blood; D005260:Female; D006221:Halothane / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D014508:Urea / Q000097:blood
D014508:Urea; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D006221:Halothane