title: [Methanol poisoning. Clinical, neuropathologic and computerized tomography findings].
abstract: In two case reports, the characteristic clinical, CT-scan and neuropathological findings in acute methanol intoxication are described. The significance of acidosis for the survival rate and development of late sequelae is stressed. After a latency period of several days, one patient developed the rare condition of haemorrhagic leucoencephalopathy with striking CT-scan and morphological findings. The etiology of this complication is discussed. The principle therapeutic procedures including the correction of acidosis, haemodialysis and administration of ethanol and folic acid are outlined.
mesh_terms: D000138:Acidosis / Q000139:chemically induced; D000328:Adult; D001921:Brain / Q000473:pathology; D001929:Brain Edema / Q000139:chemically induced; D003128:Coma / Q000139:chemically induced; D005260:Female; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000139:chemically induced* / Q000473:pathology; D000432:Methanol / Q000506:poisoning*; D009336:Necrosis; D011115:Polyneuropathies / Q000139:chemically induced; D014057:Tomography, X-Ray Computed
chemical_list: D000432:Methanol
vernacular_title: Die Methanol-Intoxikation. Klinische, neuropathologische und computertomografische Befunde.