[Mechanism of fibrin formation in the tissues in gastric adenocarcinoma].
The investigation of extracts from intact and tumour tissues of the human stomach has revealed that adenocarcinoma tissues possess abnormal antiheparin, antithromboplastin and fibrin-stabilizing activity. Heparin activity, as well as the level of antithrombin III and fibrinogen-heparin complex were sharply reduced. The accumulation of anti-heparin compounds normalizing heparin and displacing the coagulating albumin from the complex with anticoagulant is believed to be one of the most important factors of fibrin production in the tumour.
D000230:Adenocarcinoma / Q000378:metabolism*; D000368:Aged; D001777:Blood Coagulation; D005260:Female; D005337:Fibrin / Q000096:biosynthesis*; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000378:metabolism*
D005337:Fibrin
K mekhanizmu obrazovaniia fibrina v tkaniakh adenokartsinomy zheludka.