[Involvement of catecholamine mechanisms in the activation of the mouse hypophyseal-testicular complex induced by the presence of females].
A study was made of the role of the adrenergic and dopamine mechanisms in the activation of endocrine testicular function of CBA/Lac and A/He male mice induced by the presence of a female in estrus without any tactile contact with a male. The alpha-adrenoreceptor blocker phentolamine inhibited an increase in the peripheral blood plasma testosterone level caused by the receptive female challenge. Propranolol blockade of beta-adrenoreceptors sharply increased the stimulating effect of the receptive female presence on the blood testosterone level. The expression of adrenoblocker action on the blood male sex hormone level depended on a male genotype. The dopamine receptor blocker pimozide produced a moderate effect on the blood testosterone but an attempt to separate its influence into the male sex hormone tonic secretion and the blood testosterone level against a background of sex activation failed. It was concluded that the adrenergic mechanisms were involved in the hypothalamo-hypophyseotesticular complex activation induced by the receptive female presence.
D000818:Animals; D001143:Arousal / Q000502:physiology*; D004971:Estrus; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010902:Pituitary Gland / Q000502:physiology*; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000502:physiology*; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D012726:Sexual Behavior, Animal / Q000502:physiology*; D013045:Species Specificity; D013737:Testis / Q000502:physiology*; D013739:Testosterone / Q000097:blood
D011941:Receptors, Adrenergic; D011954:Receptors, Dopamine; D013739:Testosterone
Uchastie katekholaminovykh mekhanizmov v aktivatsii gipofizarno-semennikovogo kompleksa mysheĭ, indutsirovannoĭ éffektom prisutstviia samki.