[Noradrenaline content of the brain of rats of various ages following adaptation to a new situation and to the development of a passive avoidance conditioned reflex].
Noradrenaline (NA) levels in cortico-striatal (including cerebral cortex, hippocamp, striatum) and hypothalamo-brainstem (including hypothalamus, thalamus, tectum + tegmentum) regions were determined by fluorometry in I- and 2-month-old male rats after 7-day adaptation to experimental conditions and passive avoidance learning by single electric foot shock. Neither the new environment nor a week's adaptation to it resulted in any significant alteration of NA content in both brain regions of 1- and 2-month-old rats. No considerable differences in NA levels were found in rats of both age groups with and without passive avoidance responses. But 24 hours after the exposure to foot shock NA basal levels markedly decreased in both brain regions of 1-month-old rats, while in 2-month-old ones NA basal levels markedly increased in hypothalamo-brainstem region.
D000222:Adaptation, Physiological; D000375:Aging / Q000502:physiology*; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001923:Brain Chemistry; D003214:Conditioning, Classical / Q000502:physiology*; D008297:Male; D009638:Norepinephrine / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D009638:Norepinephrine
Soderzhanie noradrenalina v mozge krys raznogo vozrasta posle adaptatsii k novoĭ obstanovke i vyrabotki uslovnogo refleksa passivnogo izbeganiia.