[Morphofunctional changes in the adrenergic innervation of the major cerebral arteries during bilateral electrostimulation of the locus coeruleus].
The intramural adrenergic nervous apparatus of cerebral arteries was studied in adult rabbits after 3-10 sessions of electrical stimulation of locus coeruleus. The activity of nerve structures was determined by estimating the density of adrenergic perivascular plexuses and by semi-quantitative cytophotometry of changes in the catecholamine content of nerve varicosities. The stimulation was followed by a 28.2 +/- 1.5% increase in adrenergic innervation density. while catecholamine content in perivascular nerve structures displayed a tendency to decrease. The problem of central effects on cerebral blood flow autoregulation is discussed.
D000320:Adrenergic Fibers / Q000033:anatomy & histology* / Q000502:physiology; D000818:Animals; D002395:Catecholamines / Q000378:metabolism; D002536:Cerebral Arteries / Q000294:innervation*; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D006651:Histocytochemistry; D008125:Locus Coeruleus / Q000502:physiology*; D008163:Luminescent Measurements; D008526:Medulla Oblongata / Q000098:blood supply; D011817:Rabbits
D002395:Catecholamines
Morfofunktsional'nye izmeneniia adrenergicheskoĭ innervatsii magistral'nykh arteriĭ mozga pri bilateral'noĭ élektrostimuliatsii golubogo piatna.