title: Triphenyl phosphate allergy from spectacle frames.
abstract: A case of triphenyl phosphate allergy from spectacle frames is reported. Patch tests with analytical grade triphenyl phosphate, tri-m-cresyl phosphate, and tri-p-cresyl phosphate in the concentrations 5%, 0.5% and 0.05% pet. showed positive reactions to 0.05% triphenyl phosphate and 0.5% tri-m-cresyl phosphate, but no reaction to tri-p-cresyl phosphate. Gas chromatography of the tricresyl phosphate 5% pet. patch test material supplied from Trolab showed that it contained a mixture of a wide range of triaryl phosphates, including 0.08% triphenyl phosphate which is above the threshold for detecting triphenyl phosphate allergy in our patient.
mesh_terms: D000368:Aged; D002849:Chromatography, Gas; D003429:Cross Reactions; D003877:Dermatitis, Contact / Q000209:etiology*; D005139:Eyeglasses; D005260:Female; D006801:Humans; D010755:Organophosphates; D009943:Organophosphorus Compounds / Q000009:adverse effects*; D010968:Plasticizers / Q000032:analysis / Q000276:immunology; D012882:Skin Tests / Q000379:methods; D014317:Tritolyl Phosphates / Q000276:immunology
chemical_list: D010755:Organophosphates; D009943:Organophosphorus Compounds; D010968:Plasticizers; D014317:Tritolyl Phosphates; C005445:triphenyl phosphate