Macrophage activity of regional lymph nodes of cancer patients and its relation to stages of cancer.
Macrophage activity of regional lymph nodes from patients with uterine cervical cancer and patients with gastric cancer was studied. Enhanced spreading of macrophages was observed in an early stage of these cancer patients, but the rate was decreased in advanced stage. In metastatic nodes, enhanced spreading was observed in many cases. Cytostatic activity of macrophages was elevated in stage II of uterine cervical cancer and in stage I of gastric cancer. Significant relation between the rate of spreading and the cytostatic activity was observed in these patients. The reasons for change of the macrophage activity in relation to tumor burden were discussed.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007223:Infant; D008198:Lymph Nodes / Q000502:physiology*; D008264:Macrophages / Q000502:physiology*; D008875:Middle Aged; D009214:Myoma / Q000276:immunology; D009362:Neoplasm Metastasis; D013274:Stomach Neoplasms / Q000276:immunology*; D002583:Uterine Cervical Neoplasms / Q000276:immunology*