Mixtures of lecithin with polymerizable derivatives of cholesterol. A monolayer film balance study.
One of the best investigated binary lipid mixtures is the lecithin-cholesterol system. We show here that it is possible to modify the cholesterol in such a way that it can be polymerized without changing its behaviour in mixtures with lecithin. The polymerizable derivatives exhibit a very similar phase diagram in the mixture with dipalmitoylphosphatidylcholine as the cholesterol itself. This is demonstrated by filmbalance measurements.
D015060:1,2-Dipalmitoylphosphatidylcholine; D002784:Cholesterol; D002788:Cholesterol Esters; D008563:Membrane Lipids; D008956:Models, Chemical; D011108:Polymers; D013816:Thermodynamics; D014466:Ultraviolet Rays; D014783:Viscosity; D014867:Water
D002788:Cholesterol Esters; D008563:Membrane Lipids; D011108:Polymers; D014867:Water; D015060:1,2-Dipalmitoylphosphatidylcholine; D002784:Cholesterol