The appearance of 2,3-butanediol in the chronic ethanol treated pregnant rat.
The chronic administration of ethanol to pregnant rats at term results in the appearance of high concentrations of glycols such as 2,3-butanediol and 1,2-propanediol in their blood and urine. The results support the idea that 2,3-butanediol formation could be a mechanism for ethanol detoxication. The clinical implications of the findings are referred to.
D000437:Alcoholism / Q000097:blood*; D000818:Animals; D002072:Butylene Glycols / Q000097:blood*; D000431:Ethanol / Q000097:blood; D005260:Female; D008658:Inactivation, Metabolic; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D019946:Propylene Glycol; D011409:Propylene Glycols / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains
D002072:Butylene Glycols; D011409:Propylene Glycols; D000431:Ethanol; C026978:2,3-butylene glycol; D019946:Propylene Glycol