An American validation study of the Newcastle diagnostic scale. I. Relationship with the dexamethasone suppression test.
The Newcastle diagnostic index was completed on 159 depressed in-patients, who received the dexamethasone suppression test during their first week in hospital. Patients suffering from endogenous depression had a significantly higher rate of DST non-suppression, were older, were more frequently psychotic, and more frequently lost weight; even after controlling for these variables, DST non-suppression was significantly more frequent in the endogenous group. The relationship between Newcastle scores and the frequency of DST non-suppression was non-linear.
D000328:Adult; D000367:Age Factors; D001714:Bipolar Disorder / Q000175:diagnosis*; D001835:Body Weight; D003866:Depressive Disorder / Q000175:diagnosis*; D003907:Dexamethasone; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D011569:Psychiatric Status Rating Scales
D003907:Dexamethasone; D006854:Hydrocortisone