title: [Diagnostic and prognostic role of organ-specific plasma enzymes in the acute period of cerebral circulatory disorders].
abstract: Sixty-two patients with ischemic stroke were studied over time (1st-12th day) for the activity of enzymes and isoenzymes of energy metabolism (CPK, LDH, SDH). It has been shown that the brain-specific CPK BB-isoenzyme may serve as a marker of the severity and extension of brain damage while the aerobic LDH fractions may be useful in evaluation of the reversibility of hypoxic changes in the brain. The authors consider the employment of the studied enzymes for the prognosis of vascular and tissue damage.
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002561:Cerebrovascular Disorders / Q000175:diagnosis*; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007064:L-Iditol 2-Dehydrogenase / Q000097:blood*; D007770:L-Lactate Dehydrogenase / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013401:Sugar Alcohol Dehydrogenases / Q000097:blood*; D013997:Time Factors
chemical_list: D007527:Isoenzymes; D013401:Sugar Alcohol Dehydrogenases; D007064:L-Iditol 2-Dehydrogenase; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase
vernacular_title: Diagnosticheskaia i prognosticheskaia rol' organospetsificheskikh fermentov plazmy krovi v ostrom periode narusheniia mozgovogo krovoobrashcheniia.