title: Effects of ischemic nerve block on the early and late components of the stretch reflex in the human forearm.
abstract: To investigate the peripheral afferent mechanisms which mediate the short latency (M1) and long latency (M2) components of the stretch reflex, we have recorded EMG responses to extension perturbations at the wrist before and following inflation of a blood pressure cuff around the upper arm. After approximately 30 min of ischemia, the reflexes had almost completely disappeared, although subjects were still able to activate the forearm muscles voluntarily. As the ischemic block developed, the M2 component began to decrease in amplitude sooner than M1, and up to the time of complete loss of reflex activity, the suppression of M2 was relatively greater than that of M1. These results suggest that M2 may be mediated by a population of afferent fibers different from the Ia afferents which are believed to generate the M1 response.
mesh_terms: D000328:Adult; D004576:Electromyography; D005542:Forearm / Q000294:innervation / Q000502:physiology*; D006801:Humans; D007511:Ischemia / Q000503:physiopathology*; D008875:Middle Aged; D009132:Muscles / Q000294:innervation / Q000502:physiology; D009407:Nerve Block; D010525:Peripheral Nerves / Q000503:physiopathology; D011930:Reaction Time; D012026:Reflex, Stretch