title: The status of sorbent technology in hemodialysis treatment.
abstract: Twenty years ago an engineer in the aerospace field suggested the possibility of regenerating hemodialysate. This suggestion led to the development of the REDY Sorbent Hemodialysis System. In 1973, when the system was first introduced, the emphasis was on home hemodialysis. This motivation, combined with the relative portability and "no need for plumbing", led to the rapid introduction of the REDY System. Economically, the REDY System has not competed with central systems. However, the REDY System meets a special need for the preparation of individualized dialysate for the chronic and acute renal failure patient. Because of the small volume of the system (6 l), different dialysates can be readily prepared to adjust acid/base balance and normalize electrolyte concentrations. To simplify home hemodialysis, sorbent systems have now become available in which the dialysate side is disposable. This facilitates set-up and eliminates sterilization of the equipment. The Sorbent System can be reduced in size resulting in a continuously wearable hemodialysis system.
mesh_terms: D000136:Acid-Base Equilibrium; D000327:Adsorption; D002244:Carbon; D004573:Electrolytes / Q000097:blood; D006437:Hemodialysis, Home; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D006435:Renal Dialysis; D014508:Urea / Q000097:blood; D015040:Zirconium
chemical_list: D004573:Electrolytes; C027006:zirconium phosphate; D002244:Carbon; D014508:Urea; D015040:Zirconium; C028541:zirconium oxide