Bone changes in oophorectomized monkeys: CT findings.
Single and dual energy CT (75 and 125 kVp) measurements of density were made on the excised lumbar vertebrae (L5) of oophorectomized (n = 17) and control (n = 19) monkeys. The single-energy results at 75 and 125 kVp indicated an annual bone diminution of 9.1 and 10.9%, respectively, but the dual-energy determination showed only a 6.6%/year loss. The difference between single- and dual-energy results could be explained by a putative increase in marrow fat of slightly greater than 100 mg/cm3. Changes in single-energy CT density with oophorectomy and aging may be substantially overestimated.
D015502:Absorptiometry, Photon; D000818:Animals; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000502:physiology; D005260:Female; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000502:physiology; D008252:Macaca fascicularis; D008903:Minerals / Q000378:metabolism; D010052:Ovariectomy; D014057:Tomography, X-Ray Computed
D008903:Minerals