[Evaluation of the effect of obsidan in essential hypertension patients with different types of circulation].
A study of the effect of propranolol on the central hemodynamics using the polycardiographic method in 90 patients with essential hypertension showed that in 83% of them, disregarding the type of hemodynamics, beta-blocker made a negative chronotropic effect, and in 17% of the patients it increased the heart rate. In the patients with the hyperkinetic circulation the negative inotropic effect of propranolol was noted in 42% of the cases, and in the patients with the eu- and hypokinetic circulation 37.5%. However, the improvement of myocardial contractility expressed in an increase in the cardiac and stroke blood volume, the stroke and cardiac indices, and a decrease in peripheral vascular resistance were found in 24.4% of the total number of patients.
D000293:Adolescent; D000328:Adult; D002302:Cardiac Output / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D011433:Propranolol / Q000494:pharmacology / Q000627:therapeutic use*; D014655:Vascular Resistance / Q000187:drug effects
D011433:Propranolol
Otsenka deĭstviia obzidana u bol'nykh gipertonicheskoĭ bolezn'iu s razlichnymi tipami krovoobrashcheniia.