Synthesis and radiosensitizing properties of some 2-furancarboxylic acid derivatives.
New S-2-furoyl-O-alkyldithiocarbonic anhydrides have been obtained by condensation of 2-furoyl chloride with potassium O-alkyl-dithiocarbonates. The toxicity and radiosensitizing activity of these compounds were determined.
D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D005663:Furans / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D011838:Radiation-Sensitizing Agents / Q000138:chemical synthesis* / Q000633:toxicity; D013055:Spectrophotometry, Infrared; D013440:Sulfides / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity
D005663:Furans; D011838:Radiation-Sensitizing Agents; D013440:Sulfides; C048252:2-furoyl chloride