[Effect of exogenous DNA on convulsive activity].
On the corazole model of the experimental epilepsy and epileptiform activity evoked by penicillin application to the cerebral cortex with electroencephalographic registration, it has been shown that exogenous DNAs in the most cases completely or partially inhibit convulsive activity. DNA inhibited also the pacemaker activity of the Helix RPa-1 neurons.
D000818:Animals; D004247:DNA / Q000494:pharmacology / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D004569:Electroencephalography; D004827:Epilepsy / Q000139:chemically induced / Q000188:drug therapy; D006372:Helix, Snails; D006801:Humans; D009474:Neurons / Q000187:drug effects; D010406:Penicillins; D010433:Pentylenetetrazole; D051381:Rats; D012640:Seizures / Q000139:chemically induced / Q000188:drug therapy*; D013997:Time Factors
D010406:Penicillins; D004247:DNA; D010433:Pentylenetetrazole
O vliianii ékzogennoĭ DNK na sudorozhnuiu aktivnost'.