Changes in phosphorylation of nonhistone proteins during differentiation of a lower eukaryote Physarum polycephalum.
During starvation-induced differentiation of a slime mold Physarum polycephalum several changes in the phosphorylation of nuclear proteins occur. The overall content of serine- and threonine-bound phosphate drops by 50% and de novo phosphorylation of a number of nonhistone proteins is drastically altered. On the contrary, no selective dephosphorylation of nuclear proteins phosphorylated under normal growth accompanies differentiation.
D002454:Cell Differentiation; D002467:Cell Nucleus / Q000378:metabolism; D002868:Chromosomal Proteins, Non-Histone / Q000378:metabolism*; D005656:Fungal Proteins / Q000378:metabolism; D005786:Gene Expression Regulation; D008970:Molecular Weight; D010750:Phosphoproteins / Q000378:metabolism*; D010804:Physarum / Q000166:cytology / Q000378:metabolism*
D002868:Chromosomal Proteins, Non-Histone; D005656:Fungal Proteins; D010750:Phosphoproteins