[Esophageal lesions caused by oral drugs. Epidemiology, physiopathologic bases, prospectives of prevention].
Esophageal injuries caused by oral medications have recently been recognized as a iatrogenic entity. This pathogenesis is due to the retention in the esophagus of drugs with caustic properties. The main predisposing factor is the practice of taking oral drugs with a small quantity of water of and/or in a recumbent position. Elderly subjects and patients with pre-existing esophageal disorders are at higher risk, so that fluid formulations or different routes of drug administration are strongly recommended. A more widespread education to the correct use of drugs and a better drug formulation are necessary for effective prevention.
D000284:Administration, Oral; D002057:Burns, Chemical / Q000209:etiology*; D003679:Deglutition; D064420:Drug-Related Side Effects and Adverse Reactions; D004947:Esophagus / Q000293:injuries* / Q000502:physiology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D011187:Posture
Lesioni esofagee da farmaci per uso orale. Epidemiologia, basi fisiopatologiche, prospettive di prevenzione.