title: [Tooth and face abnormalities associated with pituitary growth hormone insufficiency].
abstract: Dental and facial examination has been performed in sixty-two children with idiopathic or congenital growth hormone deficiency. Fourteen (22%) had a malformation of the upper incisors and/or of the naso-frontal bud or of the eyes, associated in five with a malformation of the brain in the prosencephalon-derived areas. Moreover, fourteen patients had some facial abnormality in an area situated near that derived from the naso-frontal bud. These associations are to be considered as a clinical marker able to call for pituitary investigation in short children. They suggest that some cases of so-called idiopathic hypopituitarism relate in fact to congenital and malformative causes.
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis* / Q000196:embryology; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005145:Face / Q000002:abnormalities*; D005260:Female; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007018:Hypopituitarism / Q000150:complications* / Q000151:congenital / Q000196:embryology; D007223:Infant; D008297:Male; D014071:Tooth Abnormalities / Q000150:complications*
chemical_list: D013006:Growth Hormone
vernacular_title: Les malformations dentaires et faciales associées à l'insuffisance hypophysaire en hormone de croissance.