title: [Radical-preventive surgery in cavernous tuberculosis of the kidneys].
abstract: On the model of focal-caseous tuberculosis of kidneys in 210 rabbits it was proved that effects of antibacterial drugs in any concentration have their limits and fail to liquidate the cavernous injuries of the renal parenchyma. The investigation of long-term results of the conservative treatment of 153 patients with the cavernous tuberculosis of kidneys has completely confirmed the conclusions of experimental investigations. An analysis of long-term results of organ-preserving focal operations in experiments and clinic gave a substantial support to a real possibility to cure the pathological process. The author points to an importance to revise the idea of the leading role of the conservative antibacterial therapy in favor of wider using radical-prophylactic operations in limited cavernous tuberculosis of kidneys.
mesh_terms: D000818:Animals; D000995:Antitubercular Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D011817:Rabbits; D014398:Tuberculosis, Renal / Q000188:drug therapy / Q000601:surgery*
chemical_list: D000995:Antitubercular Agents
vernacular_title: Radikal'no-profilakticheskie operatsii pri kavernoznom tuberkuleze pochek.