[Functional changes in the argentaffin cells of the stomach and electrical activity of the brain of the rat after injection of neurotensin into the hypothalamus and 3d ventricle of the brain].
Administration of neurotensin or its analogue into the hypothalamic structures altered the degree of activity synchronization among hypothalamic and brain-stem structures, the synchronization becoming most obvious among ventro-medial nucleus, amygdala and the central grey matter. Administration of the drugs into the 3rd ventricle and paraventricular nuclei suggested antagonistic effects of these peptides at the hypothalamic level. The data obtained could be regarded as local effects of the neuropeptides upon neurons of the paraventricular nucleus and as systemic effects upon argentaffin cells of the stomach antral portion.
D000679:Amygdala / Q000187:drug effects; D000818:Animals; D001921:Brain / Q000187:drug effects*; D002838:Chromaffin System / Q000166:cytology*; D004759:Enterochromaffin Cells / Q000166:cytology*; D005753:Gastric Mucosa / Q000166:cytology*; D007276:Injections, Intraventricular; D008125:Locus Coeruleus / Q000187:drug effects; D008297:Male; D009496:Neurotensin / Q000494:pharmacology*; D010286:Paraventricular Hypothalamic Nucleus / Q000187:drug effects; D010487:Periaqueductal Gray / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D014697:Ventromedial Hypothalamic Nucleus / Q000187:drug effects
D009496:Neurotensin
Funktsional'nye izmeneniia argentaffinnykh kletok zheludka i elektricheskoĭ aktivnosti golovnogo mozga krys posle vvedeniia neĭrotenzina v gipotalamus i III zheludochek mozga.