title: Management of caustic ingestion in adults.
abstract: The treatment of 484 adults with caustic ingestion injury is discussed. Signs and symptoms are an unreliable guide to injury and a chest X-ray and fibreoptic endoscopy should be performed as soon as possible. All of the 250 patients who developed superficial lesions of the oesophagus, stomach or duodenum experienced healing without sequelae. Forty-four patients required emergency surgery of whom twenty-four died and oesophagectomy without thoracotomy is now advocated for this group, followed by interval surgery to restore continuity. The remaining 190 patients suffered gastric or oesophageal ulceration without necrosis: 92 recovered without complication, 3 succumbed to aorto-oesophageal fistula, 12 survived following delayed surgery for complications and 83 developed oesophageal and/or gastric stenosis which subsequently required endoscopic or surgical treatment.
mesh_terms: D000293:Adolescent; D000328:Adult; D002057:Burns, Chemical / Q000150:complications / Q000601:surgery*; D002424:Caustics / Q000009:adverse effects*; D004386:Duodenum / Q000293:injuries*; D004630:Emergencies; D004947:Esophagus / Q000293:injuries* / Q000601:surgery; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013270:Stomach / Q000293:injuries*; D013997:Time Factors
chemical_list: D002424:Caustics