title: Elastin in the human intervertebral disk. A histological and biochemical study comparing it with elastin in the human yellow ligament.
abstract: The elastic fiber and elastin in the human yellow ligament and intervertebral disk were studied histologically and biochemically. The elastic fiber in the human intervertebral disk, which until now had not been clearly identified microscopically, was observed clearly. We found the distribution of the elastic fiber in the intervertebral disk to be very sparse and irregular, and its diameter was small, being about one-tenth of that found in the yellow ligament. The elastin contents of the yellow ligament and intervertebral disk were 46.7% +/- 0.9% and 1.7% +/- 0.2% respectively (mean +/- SE) of the total dry weight. The amino acid composition of elastin in the yellow ligament is similar to that of other tissue, as reported in the literature; however, that found in the intervertebral disk is significantly different. It would appear, therefore, that the elastin in the intervertebral disk is of a different type from that found elsewhere.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000596:Amino Acids / Q000032:analysis; D002648:Child; D003094:Collagen / Q000032:analysis; D004547:Elastic Tissue / Q000033:anatomy & histology*; D004549:Elastin / Q000032:analysis*; D005260:Female; D006801:Humans; D007403:Intervertebral Disc / Q000032:analysis* / Q000033:anatomy & histology; D008022:Ligaments / Q000032:analysis*; D008297:Male; D008875:Middle Aged
chemical_list: D000596:Amino Acids; D003094:Collagen; D004549:Elastin