Deficiencies in the covalent binding index (CBI) for expressing in vivo binding to DNA with respect to predicting chemical carcinogenicity. A proposal for a target-organ binding index.
D000818:Animals; D002273:Carcinogens / Q000378:metabolism*; D002471:Cell Transformation, Neoplastic; D004247:DNA / Q000378:metabolism*; D008954:Models, Biological; D009928:Organ Specificity
D002273:Carcinogens; D004247:DNA