title: Computer program for calculation of kinetic and pharmacologic parameters using a 'direct linear plot' derived algorithm.
abstract: Data processing using nonparametric statistics was performed using a 'direct linear plot' algorithm of ECB. ECB (Eisenthal and Cornish-Bowden) is a computer program designed to calculate the Km and V parameters in enzyme kinetics. It is also suitable for estimation of EC50 (ligand or drug concentration for 50% effect) in pharmacological studies.
mesh_terms: D000465:Algorithms; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics; D008432:Mathematical Computing; D010600:Pharmacology; D012984:Software
chemical_list: D004798:Enzymes