title: Evaluation of a mathematical model analysing the relation between intradental nerve impulse activity and perceived pain in man.
abstract: In this investigation the usefulness and accuracy of the parameters of a mathematical model for the analysis of the effectiveness of different pain relieving procedures on pulpal pain were studied. The investigation was carried out using a previously developed mathematical/biological model on data from original subject recordings of Intradental Nerve Impulse Activity (INA) and pain estimations. Computer simulated INA and pain estimation curves were also used to enable calculation of the mathematical and biological conditions that are essential for the actual mathematical/biological model, and to facilitate the interpretation of the parameters of the model. It was shown by means of both real and simulated data that the mathematical model is well suited for the analysis of the effectiveness of some pain relieving procedures on pulpal pain. It was also shown that, by means of three new variables, the model could be made even more accurate and useful for this application.
mesh_terms: D003198:Computer Simulation; D006801:Humans; D003765:Models, Dental; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement; D010525:Peripheral Nerves / Q000503:physiopathology; D014070:Tooth / Q000294:innervation*