Allergic angiitis of Churg and Strauss syndrome. Response to pulse methylprednisolone.
Our patient presented with widespread airspace consolidation. He was a steroid-dependent asthmatic receiving moderate doses of corticosteroid therapy. Open lung biopsy showed allergic angiitis of Churg and Strauss syndrome. The patient continued to deteriorate on high doses of prednisone. He was subsequently given four pulses of intravenous methylprednisolone with dramatic clearing noted on x-ray film and resolution of his shunt.
D000328:Adult; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy; D001706:Biopsy; D006099:Granuloma / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D011241:Prednisone / Q000008:administration & dosage; D011657:Pulmonary Eosinophilia / Q000175:diagnosis / Q000188:drug therapy; D012130:Respiratory Hypersensitivity / Q000175:diagnosis / Q000188:drug therapy*; D013577:Syndrome; D014657:Vasculitis / Q000175:diagnosis / Q000188:drug therapy*
D011241:Prednisone; D008775:Methylprednisolone