Measurement of phagocytosis and cell-mediated cytotoxicity by chemiluminescence.
The generation of CL by phagocytes has been shown to be a valuable tool for monitoring the activity of phagocytic cells. It has been used to investigate mechanisms by which stimulants or inhibitors act to affect the function of phagocytic cells. CL has also been used as an assay system to detect various disease states. Last, it has been shown to be a very sensitive assay system for determining the toxicity of environmental or occupational agents on phagocytic cells.
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology; D002056:Burns / Q000276:immunology; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007154:Immune System Diseases / Q000276:immunology; D007165:Immunosuppression Therapy; D008163:Luminescent Measurements; D008722:Methods; D010587:Phagocytosis