title: Charcoal-column haemoperfusion does not significantly enhance chlormethiazole removal.
abstract: A 26-year-old man had convulsions after taking an overdose of slow-release aminophylline tablets. The convulsions were treated with an infusion of chlormethiazole and theophylline was removed by charcoal-column haemoperfusion. It has been suggested that haemoperfusion might be useful for removing chlormethiazole and this was investigated. There was no evidence that charcoal-column haemoperfusion could remove clinically significant amounts of chlormethiazole.
mesh_terms: D000328:Adult; D002606:Charcoal / Q000494:pharmacology*; D002719:Chlormethiazole / Q000378:metabolism* / Q000506:poisoning; D006464:Hemoperfusion; D006801:Humans; D008297:Male
chemical_list: D002719:Chlormethiazole; D002606:Charcoal