title: [Features of the clinical picture, course and treatment of myasthenia in late middle-aged and aged persons].
abstract: On the basis of many-year observation of 345 patients with myasthenia (M) developing in elderly and old age (from 50 to 82 years) the authors analyzed the characteristics of the clinical picture of myasthenia in this age group and determined changes in the ratio between males and females first presenting M at this age. The effect of different types of treatment and their combinations employed in these patients was determined. The authors recommend the use of pathogenetic methods of M treatment (thymectomy, X-ray therapy, and prednisolone therapy) in this age group. The most effective method is a combination of thymectomy and X-ray therapy with prednisolone administration.
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000532:radiotherapy / Q000628:therapy*; D011239:Prednisolone / Q000627:therapeutic use; D013934:Thymectomy
chemical_list: D002800:Cholinesterase Inhibitors; D011239:Prednisolone
vernacular_title: Osobennosti kliniki, techeniia i lecheniia miastenii u lits pozhilogo i starcheskogo vozrasta.