Postoperative paraplegia associated with epidural narcotic administration.
Epidural injections of buprenorphine were given for postoperative pain relief to a patient with pulmonary carcinoma who underwent a right upper lobectomy. Paraplegia occurred postoperatively and the patient's neurological status deteriorated after each injection of epidural narcotic. Laminectomies on the third postoperative day revealed an expanded oxidized cellulose (Oxycel) pledget in the epidural space. Neurologic dysfunction after epidural narcotic administration was caused by the oxidized cellulose which had migrated into the epidural space following use for surgical haemostasis and subsequently expanded with the narcotic solution and blood.
D000368:Aged; D002047:Buprenorphine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007268:Injections, Epidural; D008175:Lung Neoplasms / Q000601:surgery; D008297:Male; D010149:Postoperative Pain / Q000188:drug therapy; D010264:Paraplegia / Q000209:etiology*; D011183:Postoperative Complications / Q000209:etiology*
D002047:Buprenorphine