Pseudomelanoma of the iris in herpes simplex keratoiritis.
A 37-year-old white man with a long history of recurrent herpetic keratitis presented with a rapidly enlarging pigmented iris lesion. The primary diagnostic concern was that the lesion might be a malignant melanoma. A biopsy of the mass was done and proved it to be a granuloma with granulomatous arteritis and infarction of the iris. In a patient with a history of recurrent ocular inflammation, such a hypersensitivity granuloma should be considered in the differential diagnosis of iris melanoma.
D000328:Adult; D003937:Diagnosis, Differential; D006099:Granuloma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006561:Herpes Simplex; D006801:Humans; D007499:Iris Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D007500:Iritis / Q000150:complications / Q000209:etiology* / Q000473:pathology; D007635:Keratitis, Dendritic / Q000150:complications* / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D009336:Necrosis; D014604:Uveal Neoplasms / Q000175:diagnosis*