title: [Purpuras fulminans: development over a 15-year period].
abstract: Eighty one children were admitted in ICU between 1969 and 1983. 35% of them died. There happened in the meantime an improvement in the results (12 deaths out of 30 children admitted in hospital from 1969 to 1974, 15 deaths out of 51 children from 1975 to 1983). The improvement was obvious in the tiniest children and the less severe cases; this is mostly owing to technical progress (hemodynamic control, sedation, artificial ventilation). Corticoids and heparin were not used, or exceptionally used since 1975. Mortality in severe cases did not change. It is important to point out the fact that the four children presenting a purpura fulminans secondary to an infection with Hemophilus Influenzae died.
mesh_terms: D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011693:Purpura / Q000188:drug therapy / Q000401:mortality / Q000503:physiopathology*; D012189:Retrospective Studies; D013997:Time Factors
vernacular_title: Purpuras fulminans: évolution sur 15 ans.