[Status of local cerebral blood flow in experimental animals after transfusions of cerebrospinal fluid from patients with cerebro-subarachnoid hemorrhage and epileptic patients].
Acute and chronic rabbit experiments (n = 35) have demonstrated the changes of the local cerebral bloodflow in the frontal, parietal, and temporal lobes of the brain of animals transfused (through cannules implanted into the lateral ventricles) 0.6 ml of the patients' liquor. Transfusion of the CSF from epileptics resulted in a drastic increase of the local cerebral bloodflow, whereas transfusions of the CSF from patients with cerebro-subarachnoidal hemorrhages lead to decrease of the bloodflow intensity. These changes were recorded in 5 min after the transfusion and persisted for 3 h, their degree correlating with the disease severity. The observed responses were more intensive than those to transfusions of artificial liquor or convalescent CSF.
D000818:Animals; D001783:Blood Flow Velocity; D002540:Cerebral Cortex / Q000098:blood supply*; D002555:Cerebrospinal Fluid; D004827:Epilepsy / Q000134:cerebrospinal fluid*; D006801:Humans; D007276:Injections, Intraventricular; D011817:Rabbits; D012039:Regional Blood Flow; D013345:Subarachnoid Hemorrhage / Q000134:cerebrospinal fluid*; D014661:Vasoconstriction; D014664:Vasodilation
Sostoianie lokal'nogo mozgovogo krovotoka u éksperimental'nykh zhivotnykh pri transfuzii im likvora bol'nykh s tserebrosubarakhnoidal'nymi krovoizliianiiami i bol'nykh épilepsieĭ.