[Macrophage activation in the immune response].
In inbred white rats, immunized with sheep erythrocytes, contents and phagocytic activity of the spleen and pulmonary macrophages have been studied on the 3d, 4th, 5th, 6th, 7th, 11th, 14th and 20th days of the experiment in the light, scanning and transmissive electron microscope, as well as the effect of the cells mentioned on proliferation of lymphoid elements. Maximal phagocytic activity of the splenic and alveolar macrophages is observed on the 7th day of the experiment. At the same time, certain drop in the lymphoid cells proliferation takes place. The change in the macrophages contents also influences proliferation of the lymphoid cells.
D000818:Animals; D002452:Cell Count; D008168:Lung / Q000166:cytology / Q000276:immunology*; D008213:Lymphocyte Activation; D008262:Macrophage Activation; D008264:Macrophages / Q000648:ultrastructure; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D010587:Phagocytosis; D051381:Rats; D013154:Spleen / Q000166:cytology / Q000276:immunology*
Aktivatsiia makrofagov v immunnom otvete.