Congenital glioblastoma of the cerebellum with cytofluorometric deoxyribonucleic acid analysis.
A case of congenital glioblastoma arising from the cerebellum is presented with special reference to microspectrophotometric deoxyribonucleic acid (DNA) analysis of the tumor cells. Seven cases of this condition are already in the literature. The prognosis is poor and most of the reported cases survive no more than 2 months. Cytofluorophotometric DNA studies were helpful in elucidating the extreme heterogeneous distribution of DNA contents of the tumor cells, suggesting a biological aggressiveness probably related to the rate of proliferation.
D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D002528:Cerebellar Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D004247:DNA / Q000378:metabolism*; D005434:Flow Cytometry; D005910:Glioma / Q000151:congenital* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011859:Radiography
D004247:DNA