Monobenzone, Superfade, vitiligo and confetti-like depigmentation.
Three cases of cutaneous depigmentation after the application of Superfade are presented. Almost total depigmentation occurred on the dorsum of the hands with spread of confetti-like depigmentation to the arms. More distant spread occurred in two cases. Superfade contains 1.5% monobenzyl ether of hydroquinone (monobenzone). This is proposed as the cause of the depigmentation.
D000368:Aged; D005260:Female; D006801:Humans; D006873:Hydroquinones / Q000009:adverse effects*; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000139:chemically induced*; D014820:Vitiligo / Q000139:chemically induced*
D006873:Hydroquinones; C006429:monobenzone