[Functional electrostimulation of the denervated posticus muscle in an animal experiment: histo- and biochemical results].
Histochemical and biochemical investigations have been carried out in 2 sheep following unilateral recurrent laryngeal nerve paralysis and direct electrical stimulation of the denervated posticus muscles. The stimulation effect was determined histochemically (standard ATP-ase staining) and compared with the fibre pattern of normal posticus muscles. In addition, one-dimensional gel electrophoresis of myosin heavy-chain isoforms was carried out and correlated with the histochemical results. A dramatic increase of type I fibres could be seen after long-term low-frequency direct electrical stimulation of denervated posticus muscles of the sheep. Biochemically the amount of slow myosin heavy-chain isoforms was higher than in normal muscles.
D000818:Animals; D004558:Electric Stimulation; D007821:Laryngeal Muscles / Q000294:innervation*; D007823:Laryngeal Nerves / Q000033:anatomy & histology*; D009119:Muscle Contraction; D009121:Muscle Denervation; D009132:Muscles / Q000294:innervation*; D009218:Myosins / Q000378:metabolism; D012009:Recurrent Laryngeal Nerve / Q000033:anatomy & histology*; D012756:Sheep; D014827:Vocal Cords / Q000294:innervation
D009218:Myosins
Funktionelle Elektrostimulation des denervierten M. posticus im Tierversuch: Histo- und biochemische Ergebnisse.