Sperm/cervical mucus contact test for sperm antibodies.
Thirteen couples with a history of primary infertility for at least 3 years were selected according to the following criteria: a positive sperm/cervical mucus contact (SCMC) test, the presence of sperm-agglutinating antibodies in the cervical mucus, and/or seminal fluid of one of the partners. Nine of the males and 4 of the 13 females were accordingly treated with high dosages of corticosteroids for 6 months. Among 4 (44%) males and 2 (50%) females a pregnancy ensued. Four (80%) of the 6 patients in whom a pregnancy was reported showed not only a decline in their sperm antibody titer but also a decrease in the percent shaking spermatozoa during SCMC testing.
D000906:Antibodies / Q000032:analysis*; D002582:Cervix Mucus / Q000276:immunology*; D003075:Coitus; D005260:Female; D006801:Humans; D007246:Infertility / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D011247:Pregnancy; D012661:Semen / Q000276:immunology; D013094:Spermatozoa / Q000276:immunology*
D000906:Antibodies; D011239:Prednisolone