Hemocyte cell surface changes in Aedes aegypti in response to microfilariae of Dirofilaria immitis.
This study involved the assessment of surface changes on hemocytes of Aedes aegypti black-eyed Liverpool strain in association with the melanization response against intrathoracically inoculated Dirofilaria immitis microfilariae (mff). Surface changes on hemocytes were identified using fluorescein-labeled wheat germ agglutinin (WGA). In mosquitoes eliciting a melanization response against inoculated mff, there was a 5-fold increase in the percentages of hemocytes exhibiting WGA binding compared with saline inoculated controls. Relationships of this hemocyte activation in relation to cell-mediated melanization responses of adult mosquitoes against mff are discussed.
D000330:Aedes / Q000276:immunology / Q000469:parasitology*; D000818:Animals; D001773:Blood Cells / Q000378:metabolism*; D004183:Dirofilaria immitis / Q000502:physiology*; D005370:Filarioidea / Q000502:physiology*; D006434:Hemocytes / Q000378:metabolism*; D008842:Microfilariae / Q000502:physiology; D014909:Wheat Germ Agglutinins / Q000378:metabolism
D014909:Wheat Germ Agglutinins