A trypsin inhibitor isolated from lymphatic leukemia cells.
A trypsin inhibitor from murine L 1210 lymphatic leukemia cells was isolated on QAE Sephadex A-50 and Trypsin-Sepharose 4B and purified about 197 times. It is a thermostable peptide, nonsensitive to changes in the pH range 2-10. It inhibits trypsin proteolytic activity against hemoglobin, azocaseine and trypsin esterase activity.
D000818:Animals; D002846:Chromatography, Affinity; D007700:Kinetics; D007939:Leukemia L1210 / Q000378:metabolism*; D051379:Mice; D008811:Mice, Inbred DBA; D014357:Trypsin / Q000378:metabolism; D014361:Trypsin Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology
D014361:Trypsin Inhibitors; D014357:Trypsin