title: [Approaches to genetic control for the use of pesticides].
abstract: Analysis of data available in literature has shown that 65% of 400 pesticides studied for their mutagenicity exert a mutagenic effect on any test-object. The number of revealed mutagens approaches 100% when four or more test-objects are used. Recommendations for quantitative estimation of genetic risk worked out under conditions of model experiments with standard mutagens are not available for pesticides since they are slight mutagens. The necessity for genetic stage-by-stage monitoring of pesticide use is substantiated. This monitoring should be carried out at the stage of experimental studies by means of classifications by the degree of potential mutagenic danger (the method is described) and at the stage of ecological and genetic investigations--by means of the regulation for application with due regard for the summary mutagenic background.
mesh_terms: D000818:Animals; D004787:Environmental Pollution / Q000517:prevention & control*; D006801:Humans; D009152:Mutagenicity Tests; D009153:Mutagens; D010575:Pesticides / Q000633:toxicity*; D012306:Risk
chemical_list: D009153:Mutagens; D010575:Pesticides
vernacular_title: O taktike geneticheskogo kontrolia za primeneniem pestitsidov.