[Course of the annual incidence of primary glomerulopathies in a population of 400,000 inhabitants over a 10-year period (1976-1985)].
Between January 1976 and December 1985, renal biopsy was indicated in 663 adults (greater than 15 yrs) patients who were born and lived in a rural area of 400,000 inhabitants. Annual incidence (AI) was 16.5/100,000. Primary GN was diagnosed in 418 pts (63%) corresponding to a prevalence (P) for 10 yrs of 1/1000. The results have been compared for two periods: A (1976-1980) and B (1981-1985) for which the number of patients with primary GN was similar (205 vs 213, AI: 10.3 vs 10.6/100,000). Sex-ratio M/F (2.1 vs 1.8) and mean age (+/- SD) at the time of renal biopsy (45 +/- 17) were not different. P (%) among primary GN, P (nb/1000) among global population, AI (nb/100,000) and sex-ratio (A vs B) were evaluated for each histological type: lipoid nephrosis (MC and HSF): 9.8%, 0.1/1000, 1.2 vs 0.8/100,000 (ns), 1 vs 1.5 (ns). Membranous nephropathy 12.4%, 0.13/1000, 1.1 vs 1.5/100,000 (ns), 1.75 vs 0.8 (less than 0.02). IgAGN (Berger): 27%, 0.28/1000, 2.6 vs 3/100,000 (ns), 3 vs 3.3 (ns). IgAGN (Schönlein-Henoch): 5%, 0.05/1000, 0.45 vs 0.6/100,000 (ns), 3 vs 5 (ns). MPGN: 5.9%, 0.06/1000, 1 vs 0.25/100,000 (less than 0.01), 2.3 vs 1.5 (ns). Post streptococcal AGN: 2.8%, 0.03/1000, 0.55 vs 0.05/100,000 (less than 0.01). Non post-streptococcal AGN: 6.7%, 0.07/1000, 0.65 vs 0.75/100,000 (ns), 1.2 vs 0.6. Idiopathic crescentic GN: 4.7%, 0.05/1000, 0.25 vs 0.75/100,000 (less than 0.01) 1.5 vs 1.5. S and F proliferative GN: 1.9%, 0.02/1000, 0.15 vs 0.25/100,000 (ns), 2 vs 0.2.(ABSTRACT TRUNCATED AT 250 WORDS)
D000328:Adult; D000367:Age Factors; D000368:Aged; D001706:Biopsy; D005260:Female; D005602:France; D005921:Glomerulonephritis / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors
Evolution de l'incidence annuelle des glomérulopathies primitives dans une population de 400,000 habitants au cours d'une période de 10 ans (1976-1985).