Cefoxitin and cefamandole levels in the human bile.
The bile levels of cefoxitin and cefamandole were studied in 75 patients. The two antibiotics were shown to be present at high concentration and to undergo a rapid metabolization. It is concluded that they represent the antibiotics of choice in the prophylactic and therapeutic treatment of biliary tract infections.
D001646:Bile / Q000378:metabolism*; D001649:Bile Duct Diseases / Q000378:metabolism / Q000601:surgery; D002435:Cefamandole / Q000032:analysis* / Q000097:blood; D002440:Cefoxitin / Q000032:analysis* / Q000097:blood; D002769:Cholelithiasis / Q000378:metabolism / Q000601:surgery; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D008826:Microbial Sensitivity Tests; D012505:Sarcina / Q000187:drug effects
D002435:Cefamandole; D002440:Cefoxitin