title: Siccanin: a new antifungal antibiotic with antidermatophytic properties. In vitro studies.
abstract: The in vitro antifungal properties of the antibiotic siccanin were determined by the minimal inhibitory concentrations (MIC) values against 51 fungal strains (yeasts and filamentous fungi). The comparison was made with econazole, clotrimazole, 5-fluorocytosine and griseofulvin. The results show the useful antidermatophytic activity of siccanin.
mesh_terms: D003883:Arthrodermataceae / Q000187:drug effects*; D002175:Candida / Q000187:drug effects; D003022:Clotrimazole / Q000494:pharmacology; D004464:Econazole / Q000494:pharmacology; D004821:Epidermophyton / Q000187:drug effects; D005437:Flucytosine / Q000494:pharmacology; D006118:Griseofulvin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects; D014249:Trichophyton / Q000187:drug effects; D014966:Xanthenes / Q000494:pharmacology
chemical_list: D014966:Xanthenes; D006118:Griseofulvin; D004464:Econazole; D005437:Flucytosine; D003022:Clotrimazole; C001795:siccanin