Effects of two tranquilizers, reserpine and chlorpromazine, on neurosecretory cells and the ovary of the fiddler crab, Uca pugilator.
Reserpine produced alterations in neurosecretory cell types I and II in the eyestalk, brain, and thoracic ganglion, most notably a decrease in the amount of stored neurosecretory material. The ovarian index decreased, but the oocyte area increased in the reserpinized crabs. Chlorpromazine did not produce any significant changes in the structure of cell types I and II. In spite of having a normal area, the oocytes in the chlorpromazine injected crabs were devoid of yolk. Neurosecretory cell type III showed no change.
D000818:Animals; D003386:Brachyura / Q000378:metabolism*; D001923:Brain Chemistry / Q000187:drug effects; D002746:Chlorpromazine / Q000494:pharmacology*; D005260:Female; D005724:Ganglia / Q000378:metabolism; D066298:In Vitro Techniques; D009490:Neurosecretory Systems / Q000166:cytology / Q000187:drug effects*; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000166:cytology / Q000187:drug effects*; D012110:Reserpine / Q000494:pharmacology*
D012110:Reserpine; D002746:Chlorpromazine