title: [Clinical x-ray dynamics of patients with Kashin-Bek disease and in subjects at risk].
abstract: During expeditions clinical and roentgenological symptoms were studied in 129 persons aged under 25 and 53 persons aged over 25 with threatened Kashin-Bek disease and afflicted with it, who were followed-up. Observation over time showed that preclinical signs in the form of x-ray morphological changes in the hand joints were the following: a niche in the fifth finger middle phalanx metaphysis or (less frequently) in the thumb ungual phalanx and foci of epiphyseal outer resorption. The initial characteristic clinical signs of the disease were deformity of the proximal interphalangeal joints of the II-V fingers and brachydactyly of the fifth finger. Early clinical and roentgenological signs of Kashin-Bek disease were specified in the time course of the study improving thus the diagnosis and follow-up of such patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005384:Finger Joint / Q000000981:diagnostic imaging; D005385:Fingers / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010007:Osteochondritis / Q000000981:diagnostic imaging*; D011859:Radiography; D012306:Risk; D013577:Syndrome
vernacular_title: Kliniko-rentgenologicheskaia dinamika u bol'nykh s bolezn'iu Kashina-Beka i lits, kotorym ona ugrozhaet.