DNA content in renal cell carcinoma. A comparison between flow and static cytometric methods.
Different flow and static cytometric techniques for analysis of DNA content were compared using imprints, fresh and paraffin-embedded tissues from renal cell carcinomas. All methods discriminated between diploid-/near diploid and aneuploid samples and gave comparable results concerning modal ploidy levels (r = 0.744-0.970). For retrospective investigations of renal cell carcinoma, flow cytometry using paraffin-embedded tissues seemed to be the method of choice in determination of DNA content.
D002292:Carcinoma, Renal Cell / Q000032:analysis* / Q000235:genetics; D004273:DNA, Neoplasm / Q000032:analysis*; D005434:Flow Cytometry; D006801:Humans; D007680:Kidney Neoplasms / Q000032:analysis* / Q000235:genetics; D011003:Ploidies
D004273:DNA, Neoplasm