Synthesis of trifluoromethylisoxazoloazines.
When reacted with mixtures of phosphorus pentoxide, aniline, and triethylamine hydrochloride, 5-acetamidoisoxazoles (2 and 3) gave isoxazolo[5,4-d]pyrimidines (4 and 7, respectively). The same reagent and cyclohexanone were used to prepare the isoxazoloquinoline 8.
D000588:Amines; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis; D055598:Chemical Phenomena; D002621:Chemistry; D007555:Isoxazoles / Q000138:chemical synthesis*; D010080:Oxazoles / Q000138:chemical synthesis*; D010758:Phosphorus; D017553:Phosphorus Compounds; D011743:Pyrimidines / Q000138:chemical synthesis
D000588:Amines; D000900:Anti-Bacterial Agents; D007555:Isoxazoles; D010080:Oxazoles; D017553:Phosphorus Compounds; D011743:Pyrimidines; D010758:Phosphorus; C012500:phosphorus pentoxide