Changes in gonadotrophin concentrations are not necessarily involved in ovarian compensation after unilateral ovariectomy in sheep.
Ewes were unilaterally ovariectomized and/or hypophysectomized and treated with PMSG and hCG. For a given gonadotrophin treatment the ovulation rate per ewe was maintained, i.e. the ovulation rate of the remaining ovary was significantly increased (P less than 0.05), after the removal of one ovary in hypophysectomized and in pituitary-intact ewes. It is concluded that compensation of ovulation rate in the remaining ovary after unilateral ovariectomy in the sheep may be independent of feedback from the ovary and the release of gonadotrophins from the pituitary gland.
D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D005260:Female; D006064:Gonadotropins, Equine / Q000494:pharmacology*; D007016:Hypophysectomy; D010052:Ovariectomy; D010053:Ovary / Q000187:drug effects / Q000502:physiology*; D010060:Ovulation / Q000187:drug effects*; D012756:Sheep
D006063:Chorionic Gonadotropin; D006064:Gonadotropins, Equine