In vivo determination of body iron stores by natural-abundance deuterium magnetic resonance spectroscopy.
Induction of iron overload in mice using 1% (w/w) dietary carbonyl iron resulted in marked decreases in 1H and 31P NMR relaxation times. Natural-abundance deuterium (2H) NMR spectroscopy has been used to measure 2H T1 values in vivo in the presence of body paramagnetic iron. This procedure offers a method for noninvasive determination of body iron stores.
D000818:Animals; D001823:Body Composition; D005260:Female; D007501:Iron / Q000032:analysis*; D008099:Liver / Q000033:anatomy & histology; D009682:Magnetic Resonance Spectroscopy; D008433:Mathematics; D051379:Mice
D007501:Iron