[Adenosquamous carcinoma originating from the thyroid gland--report of a case and review of the literature].
Adenosquamous cell carcinoma originating from the thyroid gland is extremely rare. Only a few cases have been reported by light-microscopic observations. Like pure squamous cell carcinoma of the thyroid gland, it is generally thought to originate from the thyroid follicular epithelium and to be concerned with squamous metaplasia of the follicular epithelium. In our case, papillary adenocarcinoma was found in the thyroid gland, with the transition to squamous cell carcinoma. Immunohistochemical study for thyroglobulin and keratin further implied he transition of adenosquamous cell carcinoma in the thyroid gland. The origins of squamous cells in thyroid carcinoma are briefly discussed.
D000231:Adenocarcinoma, Papillary / Q000473:pathology*; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D006801:Humans; D008297:Male; D013964:Thyroid Neoplasms / Q000473:pathology*