An unusual case of post-transfusion purpura: good transient response to high-dose immunoglobulin.
A 62-year-old woman with an unusually protracted post-transfusion purpura failed to respond to three 3-litre plasma exchanges and prednisolone (50 mg/day) for 10 days but then had a good though transient response to two courses of high-dose immunoglobulin infusions with cessation of bleeding. The subsequent recurrent thrombocytopenia was mild and asymptomatic and only partially controlled by corticosteroids but finally resolved completely after 5 months.
D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000008:administration & dosage* / Q000627:therapeutic use; D007262:Infusions, Intravenous; D008875:Middle Aged; D011696:Purpura, Thrombocytopenic / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D065227:Transfusion Reaction
D007074:Immunoglobulin G