title: [Optimization of the antibiotic therapy in treating acute complicated cholecystitis].
abstract: High efficiency of interstitial electrophoresis on the hepatic area after administration of kanamycin was shown on the basis of experimental (40 experiments in dogs) data and clinical examinations (52 patients).
mesh_terms: D000208:Acute Disease; D000368:Aged; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001646:Bile / Q000378:metabolism; D002764:Cholecystitis / Q000150:complications / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D004195:Disease Models, Animal; D004285:Dogs; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D005260:Female; D006801:Humans; D007478:Iontophoresis / Q000379:methods; D007612:Kanamycin / Q000008:administration & dosage / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents; D007612:Kanamycin
vernacular_title: Optimizatsiia antibiotikoterapii pri lechenii ostrogo oslozhnennogo kholetsistita.