Can raising cerebral blood flow improve outcome after acute cerebral infarction?
Cerebral blood flow correlates poorly with outcome after stroke, and most therapies aimed at increasing cerebral perfusion have not succeeded in predictably reducing neurological deficit. Newer approaches such as hemodilution and thrombolysis may prove to be more effective but might be most advantageous if combined with efforts to correct postischemic disturbances in cellular metabolism.
D001809:Blood Viscosity / Q000187:drug effects; D002545:Brain Ischemia / Q000378:metabolism; D002544:Cerebral Infarction / Q000188:drug therapy* / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000187:drug effects; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006438:Hemodilution; D006801:Humans; D014665:Vasodilator Agents / Q000627:therapeutic use
D005343:Fibrinolytic Agents; D014665:Vasodilator Agents