[Characteristics of the spontaneous humoral immunity reactions to collagen type I in systemic lupus erythematosus patients].
A study of the state of the humoral immunity in 36 SLE patients made it possible to detect an increase in the level of autoantibodies to type I collagen in comparison to the level of autoantibodies in healthy donors. It showed correlation with the activity of a process, its course, clinical signs of disease, progression of renal pathology and the levels of antinuclear factor and gamma globulins.
D000293:Adolescent; D000328:Adult; D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis*; D002908:Chronic Disease; D003094:Collagen / Q000276:immunology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008181:Lupus Nephritis / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011928:Raynaud Disease / Q000276:immunology
D001323:Autoantibodies; D003094:Collagen
Osobennosti spontannykh reaktsiĭ gumoral'nogo immuniteta k kollagenu I tipa u bol'nykh sistemnoĭ krasnoĭ volchankoĭ.