Accelerated myelination in early Sturge-Weber syndrome demonstrated by MR imaging.
Magnetic resonance imaging of the brain in two infants with Sturge-Weber syndrome has demonstrated a pattern of accelerated myelination in the abnormal cerebral hemisphere. The extent of myelination was most apparent on the T1-weighted inversion recovery sequence while the T2-weighted images demonstrated concomitant changes in hydration of the brain. We propose an explanation for this finding based on cerebral ischemia underlying the leptomeningeal angioma.
D000798:Angiomatosis / Q000473:pathology*; D001921:Brain / Q000473:pathology*; D002831:Choroid Plexus / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D009682:Magnetic Resonance Spectroscopy; D009186:Myelin Sheath / Q000473:pathology*; D013341:Sturge-Weber Syndrome / Q000473:pathology*; D013997:Time Factors