Absence of anti-Müllerian activity of inhibin in the chick embryo.
Inhibin extracted from bovine follicular fluid and administered to chick embryos at a dosage increasing from 0.4 to 30 micrograms per embryo did not induce the regression of the Müllerian ducts of treated females. This result contrasts with that obtained with a testis graft which acts through its anti-Müllerian hormone. Although both hormones were of glycoproteic nature and secreted by the same cells, this study shows no functional analogy between them.
D000818:Animals; D002642:Chick Embryo; D005260:Female; D007265:Inhibins / Q000494:pharmacology*; D008297:Male; D009095:Mullerian Ducts / Q000033:anatomy & histology / Q000187:drug effects*; D013737:Testis / Q000502:physiology / Q000637:transplantation; D014184:Transplantation, Homologous
D007265:Inhibins