[The significance of arterial hypertonia and cerebral vessel wall changes within the scope of hemorheologic changes in ischemic insult].
The frequency of vascular risk factors and of hemorheologic alterations has been investigated in 163 patients with ischaemic cerebrovascular disease and was related to angiographical findings. Hemorheologic abnormalities were observed in 57% of the patients but lesions of the cerebral vessel walls displayed by angiography were present in 85%. The leading risk factor was hypertension which was diagnosed in 42% of the patients, however, their hemorheologic profile did not differ significantly from the normotensive stroke patients. Indeed, the frequency of hypertension was significantly higher in patients with severe vessel wall lesions. The important role of hemorheologic disturbances seems to be the deterioration of the hemodynamic situation provoked by vessel wall lesions.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000097:blood* / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000473:pathology* / Q000503:physiopathology; D002550:Cerebral Veins / Q000473:pathology* / Q000503:physiopathology; D048909:Diabetes Complications; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006400:Hematocrit; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012212:Rheology; D012306:Risk
D005340:Fibrinogen
Die Bedeutung der arteriellen Hypertonie und zerebraler Gefässwandveränderungen im Rahmen hämorheologischer Veränderungen beim ischämischen Insult.