title: [Telematic multicenter study of Pragmarel 100 mg (trazodone)].
abstract: Trazodone is a molecule which is already well known throughout the world for its antidepressant properties and its good global safety. We have conducted a large national study in outpatients. By means of a computerized communication network (233 psychiatrists equipped with Minitel), almost 2,000 depressed patients have been followed over a four week period of treatment with Pragmarel 100 mg, in less than three months. Computerized DSM III diagnostic criteria were used to define two sub-groups of patients. The results confirm the therapeutic indications of trazodone in various forms of depression, major affective disorders (689 cases) and other affective disorders (1,257 cases). 82% good and very good results were obtained in the overall population of patients, with a decrease by more than 50% in the initial score on the MADRS scale in 65% of cases. The low incidence of side effects and the excellent acceptability of treatment also confirm the date reported in the literature.
mesh_terms: D000328:Adult; D003195:Computer Communication Networks; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D014196:Trazodone / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D014196:Trazodone
vernacular_title: Etude multicentrique télématique de pragmarel 100 mg (trazodone).