title: Post-weaning coccidiosis in beef calves in the dry tropics: experimental control with continuous monensin supplementation via intra-ruminal devices and concurrent epidemiological observations.
abstract: Post-weaning Eimeria zuernii coccidiosis in beef calves was treated prophylactically with monensin from intra-ruminal continuous release devices. The evaluation of four treatments during three consecutive years also allowed observations on the epidemiology of this disease to be made. Monensin was an effective prophylactic and the intra-ruminal devices were a convenient method of continuous administration over a one to two month period. The three years of the trial included two characteristically very dry and one unusually wet weaning period. Coccidiosis was more severe in the dry years suggesting that oocyst challenge was less important than the immunodepressive effect of weaning and dietary stress in precipitating disease. Severe disease also occurred in calves subsequent to elimination of oocyst shedding by monensin during the initial treatment trial. The occurrence of disease in conditions inimical to oocyst survival and development and after treatment suggested a role for arrested endogenous stages.
mesh_terms: D000818:Animals; D001315:Australia; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D002980:Climate; D003048:Coccidiosis / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D003692:Delayed-Action Preparations; D008985:Monensin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D012417:Rumen / Q000187:drug effects; D014886:Weaning
chemical_list: D003692:Delayed-Action Preparations; D008985:Monensin