Adverse reactions to xenon-enhanced CT cerebral blood flow determination.
Fourteen institutions performed 1,830 computed tomographic (CT) cerebral blood flow (CBF) examinations with 32% inhaled stable xenon. Respiratory rate delay greater than 10 seconds occurred in 3.6% of patients, with 83% of the delays lasting 10-15 seconds. There was no incident of prolonged respiratory difficulty. Headache (0.4%), seizures (0.2%), nausea and vomiting (0.2%), and change in neurologic status (0.1%) were uncommon, and there were no transient ischemic attacks. The CT CBF method with 32% inhaled stable xenon is thus associated with an acceptably low incidence of adverse reactions.
D001921:Brain / Q000098:blood supply; D002560:Cerebrovascular Circulation; D003864:Depression, Chemical; D006261:Headache / Q000139:chemically induced; D006801:Humans; D009325:Nausea / Q000139:chemically induced; D012119:Respiration / Q000187:drug effects; D012640:Seizures / Q000139:chemically induced; D014057:Tomography, X-Ray Computed; D014839:Vomiting / Q000139:chemically induced; D014978:Xenon / Q000009:adverse effects*
D014978:Xenon