[Inhibitory effect of human plasma on 17-1A-dependent cellular cytotoxicity].
Mouse monoclonal antibody 17-1A-dependent cellular cytotoxicity hardly revealed any killer activity in the presence of human plasma, nor did 17-1A show complement-dependent cytotoxicity. ADCC of 17-1A-armed effector cells was also inhibited by human plasma. These results were caused by the inhibition of 17-1A binding to the Fc receptors of effector cells.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D000920:Antibody-Dependent Cell Cytotoxicity; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D009000:Monocytes / Q000276:immunology; D010949:Plasma / Q000276:immunology*
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G