[Effect of the nonspecific prevention of thrombogenic complications on late results in the combined treatment of bladder cancer].
Altogether 106 patients with bladder carcinoma (Stage T3NxMo) after combined treatment were followed-up for 5 yrs. Nicotinic acid and aspirin at common doses were administered to 51 patients (the 1st group) during pre- and post-operative radiation therapy. The other 55 patients (the 2nd group) did not receive these drugs. Relapses were noted in 33.3% of the patients of the 1st group and in 76.3% of the patients of the 2nd group. The 5-year survival in the 1st group was 72.5% and in the 2nd group 27.4%. The administration of nicotinic acid and aspirin to patients during pre- and postoperative gamma-beam therapy was shown to raise the body antitumor resistance.
D000328:Adult; D000368:Aged; D001241:Aspirin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009525:Niacin / Q000627:therapeutic use; D011182:Postoperative Care; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D013927:Thrombosis / Q000517:prevention & control*; D001743:Urinary Bladder / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000532:radiotherapy*
D009525:Niacin; D001241:Aspirin
Vliianie nespetsificheskoĭ profilaktiki trombogennykh oslozhneniĭ na otdalennye rezul'taty kombinirovannogo lecheniia raka mochevogo puzyria.