The effectiveness of a cation resin (Kayexalate) as an adsorbent of paraquat: experimental and clinical studies.
The cation-exchange-resin Kayexalate has an adsorption capacity for paraquat 15 times greater than activated charcoal and 6 times greater than Adsorbin. The oral LD50 of paraquat in rats rose 2.1 times by intragastric injection of Kayexalate. In the present study, the survival rate of rats given Kayexalate or Adsorbin after paraquat administration was examined. Results of clinical studies on 22 patients are also presented.
D000818:Animals; D002411:Cation Exchange Resins / Q000627:therapeutic use*; D006801:Humans; D007475:Ion Exchange Resins / Q000627:therapeutic use*; D008297:Male; D010269:Paraquat / Q000506:poisoning*; D011137:Polystyrenes / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains
D002411:Cation Exchange Resins; D007475:Ion Exchange Resins; D011137:Polystyrenes; C003321:polystyrene sulfonic acid; D010269:Paraquat