Uveal changes in leprosy.
A total of 424 leprosy patients were screened for uveal involvement. Uveal changes were found in 11.2% of these patients. Uveal involvement was more common in patients with greater duration of the disease and in patients on irregular Dapsone therapy. Of the patients with uveal involvement 82% were lepromatous, 16% were borderline and 2% were of tuberculoid leprosy. Uveal changes in form of active iridocyclitis (21.3%), healed iridocyclitis (58.5%), iris atrophy (10.6%), iris pearls (7.4%), small irregular pupil (46.7%), pupil refractory to dilatation (56.3%) were seen. Posterior segment involvement was rare. Lepromatous and borderline leprosy patients with no clinical evidence of uveal involvement had decreased power of accommodation as compared to normal subjects.
D000293:Adolescent; D000328:Adult; D006801:Humans; D007499:Iris Diseases / Q000209:etiology; D007918:Leprosy / Q000150:complications*; D011680:Pupil; D014603:Uveal Diseases / Q000209:etiology*; D014606:Uveitis, Anterior / Q000209:etiology