A rapid screening procedure for acidic and neutral drugs in blood by high resolution gas chromatography.
A rapid high resolution gas chromatographic method for screening acidic and neutral drugs in blood is described. The procedure involves a single extraction with ethyl acetate. Using flame ionization detection, without derivatization and with on-column methylation, more than 60 drugs of toxicologic importance are detected.
D002849:Chromatography, Gas / Q000379:methods; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008745:Methylation; D004364:Pharmaceutical Preparations / Q000097:blood*
D004364:Pharmaceutical Preparations