title: Effects of enucleation at different ages on the sizes of neurons in the lateral geniculate nucleus of infant and adult monkeys.
abstract: Cell areas have been measured in the lateral geniculate nucleus following enucleation in 7 infant and 3 adult monkeys. Deafferented cells showed rapid transneuronal degeneration. Following enucleation at birth non-deafferented parvocellular LGN cells underwent hypertrophy which was followed by a delayed return to normal size. Enucleation at 7 months of age caused marked shrinkage of non-deafferented parvocellular cells. These changes in the non-deafferented cells are similar to those following monocular lid closure at the same ages. Sizes of non-deafferented cells were unchanged following enucleation of adult monkeys.
mesh_terms: D000375:Aging; D000818:Animals; D005829:Geniculate Bodies / Q000166:cytology*; D009474:Neurons / Q000166:cytology*; D009799:Ocular Physiological Phenomena; D011323:Primates; D012683:Sensory Deprivation / Q000502:physiology*