Churg-Strauss syndrome: determining adequacy of corticosteroid dosage by the eosinophil count.
Prednisone therapy induced prompt clinical remission in a 38-year-old woman with hypereosinophilic vasculitis. Smoldering vasculitis accounts for the 38% fatality rate in treated patients with the Churg-Strauss syndrome. Complete suppression of the peripheral hypereosinophilia will reflect the efficacy of therapy more accurately than clinical response.
D000328:Adult; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy*; D004802:Eosinophilia / Q000175:diagnosis / Q000188:drug therapy*; D004804:Eosinophils; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D009336:Necrosis; D011241:Prednisone / Q000008:administration & dosage*; D013577:Syndrome; D014657:Vasculitis / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology
D011241:Prednisone