title: [Severe complications following the intrathecal administration of a methylene blue solution].
abstract: Very serious complications are reported following intrathecal injection of methylene blue. The clinical indication was to assess spontaneous rhinoliquorrhoe. It is now generally agreed that intrathecal application of dyestuff solutions, especially of methylene blue, is no longer permissible.
mesh_terms: D002493:Central Nervous System Diseases / Q000139:chemically induced*; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008751:Methylene Blue / Q000009:adverse effects*; D008875:Middle Aged
chemical_list: D008751:Methylene Blue
vernacular_title: Schwere Komplikationen nach intrathekaler Applikation von Methylenblau-Lösung.