title: Rifaximin, a rifamycin derivative for use in the treatment of intestinal bacterial infections in seriously disabled patients.
abstract: This study reports the results of an evaluation of the effectiveness and tolerability of rifaximin, an intestinal topical antibiotic. It was administered using a nasogastric tube in patients with severe enterocolitis and bacterial superinfections causing intestinal inflammatory diseases and portosystemic encephalopathy. The drug proved highly effective clinically and produced neither local nor systemic side-effects.
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000641:Ammonia / Q000097:blood; D001424:Bacterial Infections / Q000188:drug therapy*; D005260:Female; D006501:Hepatic Encephalopathy / Q000188:drug therapy; D006801:Humans; D007410:Intestinal Diseases / Q000188:drug therapy* / Q000382:microbiology; D007441:Intubation, Gastrointestinal; D008297:Male; D008875:Middle Aged; D012294:Rifamycins / Q000009:adverse effects / Q000627:therapeutic use*; D000078262:Rifaximin
chemical_list: D012294:Rifamycins; D000641:Ammonia; D000078262:Rifaximin