title: [Clinico-pathogenetic basis for using crystalline lysozyme in the combined therapy of food toxinfections].
abstract: In food toxinfections caused by various microorganisms (Staphylococcus, Escherichia, Klebsiella, Proteus, Citrobacter, etc.) a decrease of lysozyme debit and an increase of pH of gastric juice were found. One third of patients exhibited lactose deficiency of the small intestine. Treatment with furazolidone contributed to the development of lactase deficit and delayed stools normalization. Crystalline lysozyme shortened duration of febrile reaction and diarrhea, its intake facilitated lactose hydrolysis.
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D003289:Convalescence; D003460:Crystallization; D004341:Drug Evaluation; D005517:Foodborne Diseases / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D005664:Furazolidone / Q000627:therapeutic use; D005750:Gastric Juice / Q000201:enzymology; D006801:Humans; D008875:Middle Aged; D009113:Muramidase / Q000008:administration & dosage* / Q000378:metabolism; D013432:Sulfathiazoles / Q000627:therapeutic use
chemical_list: D013432:Sulfathiazoles; D005664:Furazolidone; C100300:phthalylsulfathiazole; D009113:Muramidase
vernacular_title: Kliniko-patogeneticheskoe obosnovanie primeneniia kristallicheskogo lizotsima v kompleksnoĭ terapii pishchevykh toksikoinfektsi.