title: Pulmonary vascular disease in secundum atrial septal defect in childhood: an unusual evolution.
abstract: Reported is a case of a 16-month-old girl with an isolated atrial septal defect in whom severe pulmonary hypertension has developed in 26 months in spite of an important functional gradient across the pulmonic valves at a first catheterization. Individual susceptibility to an increased pulmonary blood flow is evoked.
mesh_terms: D005260:Female; D006344:Heart Septal Defects, Atrial / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology*; D007223:Infant; D008173:Lung Diseases, Obstructive / Q000209:etiology*