Decreased number of steroid receptors of circulating lymphocytes in Crohn's disease and ulcerative colitis.
The number of steroid receptors of circulating lymphocytes was determined in 13 patients with inflammatory bowel disease and in controls. Marked reduction of the number of receptors was observed both in Crohn's disease and in ulcerative colitis; no receptors were detected by radioactive hormone binding assay in 4 cases.
D001665:Binding Sites; D003093:Colitis, Ulcerative / Q000097:blood*; D003424:Crohn Disease / Q000097:blood*; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure*; D011987:Receptors, Steroid / Q000097:blood* / Q000502:physiology; D014222:Triamcinolone Acetonide / Q000378:metabolism; D014316:Tritium
D011987:Receptors, Steroid; D014316:Tritium; D014222:Triamcinolone Acetonide