Multicentric reticulohistiocytosis.
A case of multicentric reticulohistiocytosis associated with a pleural mesothelioma is reported. The cutaneous and joint manifestations resolved after treatment with cyclophosphamide, and the remission persisted until the patient's death 3 years later. As corticosteroids have such an unpredictable effect on this condition, cyclophosphamide may be regarded as the treatment of choice until more cases can be assessed.
D000368:Aged; D006801:Humans; D008206:Lymphatic Diseases / Q000473:pathology*; D008297:Male; D008654:Mesothelioma / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013583:Synovial Membrane / Q000473:pathology