[Clinical studies on aztreonam in infections in obstetrics and gynecology].
Clinical effect was studied for aztreonam (AZT) on 2 patients being treated for malignant tumors. One-two grams of AZT was administered b.i.d. by intravenous drip infusion for 6-7 days. In case 1 with pyometra, there were excellent improvements in WBC, CRP and fever pattern. Unfavorable BUN and S-Cr. values were found, but these were considered to be side effects due to cisplatin. These improved finally, and clinical effect was also excellent. Case 2, a urinary tract infection + prophylactic postoperative administration case, was treated in combination with another drug presuming mixed infection and AZT was shown to be effective clinically and overall. No side effects in cases 1 or 2 were considered to be due to AZT.
D000328:Adult; D000368:Aged; D001398:Aztreonam / Q000008:administration & dosage / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000517:prevention & control*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication; D014552:Urinary Tract Infections / Q000517:prevention & control*; D002583:Uterine Cervical Neoplasms / Q000601:surgery; D014591:Uterine Diseases / Q000517:prevention & control*
D001398:Aztreonam