title: 3-in-1 lumbar plexus block for muscle biopsy in malignant hyperthermia patients. Amide local anaesthetics may be used safely.
abstract: A 3-in-1 lumbar plexus block with the aid of a nerve stimulator was performed in 32 patients and a psoas compartment block was performed in five patients for muscle biopsy of the upper leg for diagnosis of malignant hyperthermia (MH) susceptibility. Twenty-two patients were found to be MH susceptible by the in vitro contracture test. Twenty patients received 40 ml prilocaine 1.5% with epinephrine 1:200,000 and two received 40 ml bupivacaine 0.5% with epinephrine 1:200,000 without any untoward reaction. The 3-in-1 block provides a high success rate and excellent analgesia for muscle biopsy of the upper leg. Amide local anaesthetics are safe in MH-susceptible patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002045:Bupivacaine; D004837:Epinephrine; D006801:Humans; D007866:Leg; D008305:Malignant Hyperthermia / Q000473:pathology*; D008875:Middle Aged; D009132:Muscles / Q000473:pathology*; D009407:Nerve Block; D011318:Prilocaine
chemical_list: D011318:Prilocaine; D002045:Bupivacaine; D004837:Epinephrine