SLE-like and sicca symptoms in late component (C9) complement deficiency.
Hereditary deficiencies in early and late complement components are well known to predispose to SLE-like syndromes or recurrent infection. Hitherto reported C9 deficient cases have usually been healthy subjects, however, and it is not considered that C9 deficiency is associated with any specific disease. We describe a completely C9 deficient patient with possible Sjögren's syndrome and discuss the relationship.
D001327:Autoimmune Diseases / Q000150:complications* / Q000235:genetics; D003186:Complement C9 / Q000172:deficiency*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D012859:Sjogren's Syndrome / Q000209:etiology
D003186:Complement C9