[Effect of 17 alpha-ethinyl estradiol on the blood serum lipid indices of rats].
The administration of 17-ethinyl estradiol (0.25 mg/kg) to male Wistar rats caused on the 3rd day a decrease of the levels of free and esterified cholesterol, blood serum triglycerides and also a reduction of the content of esterified cholesterol with respect to total cholesterol while the lecithin-cholesterol-acyltransferase activity appeared to be unchanged. The effect of ethinyl estradiol on blood lipid parameters against the background of lipemia induced by triton WR 1339 was reduced.
D000818:Animals; D004353:Drug Evaluation, Preclinical; D004997:Ethinyl Estradiol / Q000494:pharmacology* / Q000627:therapeutic use; D000960:Hypolipidemic Agents; D008064:Lipidoses / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy; D008055:Lipids / Q000097:blood*; D008297:Male; D011092:Polyethylene Glycols; D051381:Rats; D011919:Rats, Inbred Strains
D000960:Hypolipidemic Agents; D008055:Lipids; D011092:Polyethylene Glycols; D004997:Ethinyl Estradiol; C016811:tyloxapol
Vliianie 17 al'fa-étiniléstradiola na lipidnye pokazateli syvorotki krovi krys.