The articular diversity of early haemochromatosis.
This report details seven patients who had an arthropathy at presentation of their haemochromatosis. The spectrum ranged from arthralgia and normal radiographs to classic polyarthritis and the typical radiological triad of joint-space narrowing, sclerosis and cysts. Some atypical presentations are highlighted. An early diagnosis of haemochromatosis requires clinical suspicion; support can be obtained from serum iron studies, particularly saturation of iron-binding capacity and ferritin, and from biopsy of liver and/or synovium.
D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006432:Hemochromatosis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007501:Iron / Q000097:blood; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000209:etiology*; D011859:Radiography
D007501:Iron