The utilization of two frequency-shifted sinc pulses for performing volume-selected in vivo NMR spectroscopy.
A new approach to volume-selected in vivo NMR spectroscopy uses two frequency-shifted sinc pulses, in conjunction with pulsed field gradients, to destroy the coherence of the unwanted signals. A hard pi/2 pulse can then be used to read the z magnetization in the region of interest. This method is independent of T2, provides complete volume selection in a single acquisition, and can be readily implemented on most high-field commercial imaging/spectroscopy systems.
D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D013057:Spectrum Analysis