Chloroquine treatment in desquamative interstitial pneumonia.
An infant presented with failure to thrive, tachypnoea, and hypoxia reversed by oxygen. Lung function showed decreased pulmonary compliance; lung biopsy showed desquamative interstitial pneumonitis. Chloroquine 10 mg/kg/day resulted in improvement and relapse when temporarily stopped. The patient was completely asymptomatic during four years' treatment and six months after stopping treatment.
D002738:Chloroquine / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male; D011658:Pulmonary Fibrosis / Q000188:drug therapy*; D012008:Recurrence
D002738:Chloroquine