[Characteristics of an experimental model of alcoholic cardiomyopathy by diagnostic enzyme tests].
Experimental alcoholic cardiomyopathy was simulated by aminotriazole administration (1 g/kg) into chronically ethanol intoxicated rats. Activity and isozyme spectra of organospecific enzymes and bilirubin concentration were determined in blood plasma. Activity of catalase was assayed in liver and heart homogenates. The data obtained suggest that not only myocardium but also skeletal muscles were impaired in the experimental group of animals. This phenomenon appears to elucidate the similar pathological effect of ethyl alcohol on myocardium and skeletal muscles.
D000640:Amitrole / Q000494:pharmacology; D000818:Animals; D001835:Body Weight; D002310:Cardiomyopathy, Alcoholic / Q000175:diagnosis*; D004796:Clinical Enzyme Tests; D004195:Disease Models, Animal; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D000640:Amitrole
Kharakteristika éksperimental'noĭ modeli alkogol'noĭ kardiomiopatii metodami diagnosticheskoĭ énzimologii.