Resorbable materials of poly(L-lactide). VI. Plates and screws for internal fracture fixation.
Poly(L-lactide) (PLLA) with an extremely high molecular weight (Mv up to 1 X 10(6)) was synthesized at a low catalyst concentration (0.015 wt%) and temperatures between 100-110 degrees C. Besides good mechanical properties the as-polymerized PLLA exhibited a microporous structure. Plates and screws of this material were used for the treatment of mandibular fractures, both in dogs and in sheep. Bone healing was uneventful and proceeded without callus formation or signs of inflammation. Fracture healing was accompanied by a progressive degradation of the microporous implants of PLLA.
D000818:Animals; D001860:Bone Plates; D001863:Bone Screws; D004285:Dogs; D050723:Fractures, Bone / Q000628:therapy*; D008855:Microscopy, Electron, Scanning; D008970:Molecular Weight; D011091:Polyesters; D012756:Sheep; D013718:Tensile Strength
D011091:Polyesters; C033616:poly(lactide)