title: Tear film flow and stability in herpes simplex keratitis and chronic blepharitis.
abstract: Tear film flow and stability studies were carried out in patients suffering from herpes simplex keratitis and chronic blepharitis by performing Schirmer test I and tear film break-up-time (BUT) measurements. In herpes simplex keratitis the values of BUT were within normal limits. Values of Schirmer test I were significantly higher (t-test, P less than 0.001) in these patients and are considered to be due to reflex hypersecretion of tears. Schirmer test I was found to be unaffected, whereas the values of BUT seen were significantly lower (t-test, P less than 0.001) in patients suffering from chronic blepharitis. These lower values of BUT can perhaps be attributed to the altered resurfacing of precorneal tear film as a result of changes in the lid margins.
mesh_terms: D001762:Blepharitis / Q000503:physiopathology*; D002908:Chronic Disease; D005141:Eyelid Diseases / Q000503:physiopathology*; D006801:Humans; D007635:Keratitis, Dendritic / Q000503:physiopathology*; D008722:Methods; D013666:Tears / Q000378:metabolism*