Multifocal intraepidermal carcinoma in a dog histologically resembling Bowen's disease.
A middle-aged, spayed female dog developed multiple cutaneous neoplasms that had clinical and histologic features of Bowen's disease in humans. Although lesions began in sun-exposed, glabrous skin, they progressed to hairy skin and to mucous membranes. Metastasis did not occur, although one lesion eventuated in local invasion of bone. The dog subsequently developed metastatic cutaneous myxosarcoma and euthanasia was requested by the owners.
D000818:Animals; D002278:Carcinoma in Situ / Q000473:pathology / Q000662:veterinary*; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D008854:Microscopy, Electron; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary*