Tumours in Iceland. Hodgkin's disease and non-Hodgkin's malignant lymphomas. A histological classification and epidemiological considerations.
All cases of biopsy-proven Hodgkin's disease and non-Hodgkin's lymphomas submitted for histological diagnosis in Iceland during 1955-1982 and available for review were typed histologically, using the World Health Organization Classification for cases of Hodgkin's disease and the "International Working Formulation" for cases of non-Hodgkin's lymphoma. A total of 92 cases of Hodgkin's disease were classified with a male-to-female ratio of 1.96. The largest subgroups were those of nodular sclerosis (42%) and mixed cellularity (32%). A prominent peak in the incidence was found in the 21-30 years age group. The incidence and subtypes of Hodgkin's disease in Iceland appears similar to those found in other Western countries. A total of 90 cases of non-Hodgkin's lymphomas were classified with a male-to-female ratio of 1.5. A high incidence of large cell lymphomas was found, especially of the immunoblastic type (35%), while in other respects the distribution of subtypes appeared similar to what has been found in studies from other Western countries. The incidence of non-Hodgkin's lymphomas in Iceland is low during childhood and young adulthood but rises sharply after age 50 and the overall incidence is similar to that found in other European countries.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005260:Female; D006689:Hodgkin Disease / Q000145:classification / Q000453:epidemiology*; D006801:Humans; D007055:Iceland; D008228:Lymphoma, Non-Hodgkin / Q000145:classification / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors