[Portacaval anastomosis in 2 cases of homozygote familial hypercholesterolemia].
We report the cases of two siblings, both suffering from familial hypercholesterolemia in homozygotic form, followed up before and after portacaval shunt. A total parenteral nutrition failed to decrease plasma cholesterol levels. However, on the basis of clinical data, a portacaval shunt was performed at the age of seven and five and a half. The two patients showed great effectiveness of the shunt with dramatic regression of clinical signs, reduction of plasma cholesterol, without serious complications over a five to six years period after the shunt.
D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006720:Homozygote; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000601:surgery*; D007223:Infant; D008297:Male; D011167:Portacaval Shunt, Surgical
D002784:Cholesterol
Anastomose porto-cave dans deux cas d'hypercholestérolémie familiale homozygote.