[Erythrocytic reactions and metabolic shifts in long-term experimental hypercatecholaminemia].
The experiments on intact dogs have revealed that daily two-hour infusions of stressor norepinephrine doses are accompanied by the elevation in erythrocyte, hematocrit and hemoglobin levels, changes in circulating blood volume and signs of compensated metabolic acidosis. These adaptive responses become excessive in persistent hypercatecholaminemia and promote the development of stress-induced organic lesions.
D000136:Acid-Base Equilibrium / Q000187:drug effects; D000222:Adaptation, Physiological / Q000187:drug effects; D000818:Animals; D001810:Blood Volume / Q000187:drug effects; D002395:Catecholamines / Q000097:blood*; D004285:Dogs; D004912:Erythrocytes / Q000187:drug effects / Q000502:physiology*; D005260:Female; D008297:Male; D009638:Norepinephrine / Q000008:administration & dosage; D013312:Stress, Physiological / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D013997:Time Factors
D002395:Catecholamines; D009638:Norepinephrine
Eritrotsitarnye reaktsii i metabolicheskie sdvigi pri dlitel'noĭ éksperimental'noĭ giperkatekholaminemii.