Henoch-Schönlein purpura following thiram exposure.
Henoch-Schönlein purpura (HSP) is an uncommon, nonthrombocytopenic hypersensitivity vasculitis that is often idiopathic, but may be induced by infectious agents, drugs, foods, environmental chemicals, or insect bites. To our knowledge, we report the first recognized case of HSP following exposure to the widely used industrial and agricultural agent, tetramethylthiuram disulfide. Few reports of HSP or other vasculitides resulting from exposure to structurally similar compounds are available. Despite the widespread use of tetramethylthiuram disulfide, many cases of exposure may remain unrecognized, resulting in a subsequent failure to properly identify sequelae.
D000328:Adult; D000382:Agricultural Workers' Diseases / Q000139:chemically induced*; D006801:Humans; D011695:IgA Vasculitis / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D013859:Thiocarbamates / Q000009:adverse effects*; D013893:Thiram / Q000009:adverse effects*; D014197:Trees
D013859:Thiocarbamates; D013893:Thiram