Allergic interstitial nephritis due to diazepam.
A 56-year-old man developed allergic interstitial nephritis and deterioration of preexisting chronic renal failure after receiving diazepam. On discontinuation of diazepam, kidney function returned to the baseline level and itching, eosinophilia, and eosinophiluria subsided. A causative correlation between allergic interstitial nephritis and diazepam is suggested.
D003975:Diazepam / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000150:complications*; D004802:Eosinophilia / Q000150:complications; D004804:Eosinophils; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000150:complications; D014556:Urine / Q000166:cytology
D003975:Diazepam