title: Antibodies to marine caliciviruses in the Steller sea lion (Eumetopias jubatus Schreber).
abstract: Sera from 145 Steller sea lions (76 adults, three subadults, 37 pups, and 29 fetuses) were tested for neutralizing antibodies to nine marine calicivirus serotypes. Antibodies were found to San Miguel sea lion virus (SMSV) types 1, 5, 6, 7, 8, 10 and 13, and to Tillamook (bovine) calicivirus, but no antibodies were found to the walrus calicivirus. Titers (microtiter neutralization assay) ranged from 1:20 to 1:320, with many positive reactions at the higher dilutions (greater than or equal to 1:80). Antibodies to SMSV's 5 and 10 were most common among animals sampled in Alaskan waters, while antibodies to SMSV-6 were most common among pups from the southern Oregon coast. These data provide evidence that Steller sea lions, like their California sea lion (Zalophus c. californianus Lesson) counterparts, have experienced widespread exposure to multiple serotypes of marine caliciviruses.
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002139:Caliciviridae / Q000276:immunology*; D010872:Caniformia / Q000276:immunology*; D005333:Fetus / Q000276:immunology / Q000382:microbiology; D046070:Sea Lions / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral