Linear nevi, hemihypertrophy, connective tissue hamartomas, and unusual neoplasms in children.
The association of cutaneous nevi, hemihypertrophy, and connective tissue overgrowth has been described in many patients. We report long-term follow-up in two boys with such association who in addition developed testicular neoplasms. One patient also had progressive spinal cord compression as a result of stenosis of the spinal canal, and required amputation of a severely deformed limb. The importance of careful, long-term management in such patients is emphasized.
D000230:Adenocarcinoma / Q000473:pathology; D003537:Cystadenoma / Q000473:pathology; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D006984:Hypertrophy; D007223:Infant; D007866:Leg / Q000473:pathology*; D008297:Male; D009372:Neoplasms, Connective Tissue / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D009508:Nevus, Pigmented / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D013117:Spinal Cord Compression / Q000473:pathology; D013577:Syndrome; D013736:Testicular Neoplasms / Q000473:pathology