title: Physiological changes in pulmonary development related to passive smoking and its interaction with active smoking.
abstract: The growth of pulmonary function between ages 5.5 and 25 years was determined in 1502 observations on 362 subjects from a representative population study of non-Mexican American whites in Tucson. There was an average of 8.8 years of follow-up, with a maximum of 12. The model developed was robust for follow-up of 3-7 observations (3 + years). Respiratory illnesses and smoking had the biggest negative impact on growth of forced expiratory volume in 1 s (FEV1), Vmax 50%/forced vital capacity (FVC) parental smoking and airway obstructive disease (AOD) were important also. Flow measures showed present and more persistent effects of disease and smoking than did FEV1.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D006801:Humans; D008168:Lung / Q000254:growth & development* / Q000502:physiology; D012129:Respiratory Function Tests; D012306:Risk; D012907:Smoking; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
chemical_list: D014028:Tobacco Smoke Pollution