title: Metallurgical analysis of five failed cast cobalt-chromium-molybdenum alloy hip prostheses.
abstract: The clinical and metallurigical characteristics of five cast cobalt-chromium-molybdenum alloy femoral hip prostheses which failed in vivo were evaluated. The devices included: two of the Howmedica Muller-Charnley design, two of the Howmedica Charnley design, and one of the Zimmer Aufranc-Turner design. Fractographic analyses demonstrated that the five devices had failed by fatigue which originated on the lateral aspect. Failure occurred after an average in vivo time of 80.4 months (approximately 6.7 years). Only two of the devices had Rockwell hardness values that were within the ASTM specifications for the alloy. Upon metallurgical examination, moderate to severe levels of gas porosity, interdendritic shrinkage, and nonmetallic inclusions were found in all of the devices. As expected, extremely large grain sizes also were observed in the devices examined. These results indicate that the metallurgical flaws and defects associated with the cast cobalt-chromium-molybdenum alloys used in these devices may preclude successful longterm performance and warrant manufacturer's attention.
mesh_terms: D000368:Aged; D002858:Chromium Alloys / Q000009:adverse effects*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011475:Prosthesis Failure; D013314:Stress, Mechanical
chemical_list: D002858:Chromium Alloys