title: [Effect of vitamin E from by-products of cotton oil processing on the glutathione peroxidase system in rats].
abstract: The activities of glucose-6-phosphate dehydrogenase, glutathione reductase and glutathione peroxidase from liver, skeletal muscles and erythrocytes of rats fed a vitamin E-deficient, or supplemented, diet were studied. Vitamin E was added in the diet either as a pure pharmacy form of alpha-tocopherol or as a tocopherol mixture derived from oil wastes. The deficiency of vitamin E caused an increase in the activity of the above mentioned enzymes. Both alpha-tocopherol and the tocopherol mixture were found to influence the glutathione peroxidase system. The dose-dependent response of the glutathione peroxidase system was revealed. Possible mechanisms of the changes in the antioxidizing enzymes induced by vitamin E are discussed.
mesh_terms: D000818:Animals; D003369:Cottonseed Oil; D004789:Enzyme Activation / Q000187:drug effects; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism*; D005980:Glutathione Reductase / Q000378:metabolism; D051381:Rats; D014810:Vitamin E / Q000302:isolation & purification / Q000494:pharmacology*; D014811:Vitamin E Deficiency / Q000188:drug therapy / Q000201:enzymology
chemical_list: D003369:Cottonseed Oil; D014810:Vitamin E; D005954:Glucosephosphate Dehydrogenase; D005979:Glutathione Peroxidase; D005980:Glutathione Reductase
vernacular_title: Vliianie vitamina E iz otkhodov pererabotki khlopkovogo masla na glutationperoksidaznuiu sistemu krys.