Blue nevus of the endocervix. A study of five cases.
The pathologic and immunohistochemical features of 5 cases of blue nevus of the endocervix are presented: 4 of them were studied ultrastructurally. The lesions were incidentaly discovered at microscopic examination and showed pigmented dendritic cells in the cervical stroma. Immunocytochemical examination showed all cases to be positive for S-100 protein. Ultrastructurally they contained melanosomes, were surrounded by a basement membrane, and displayed occasional desmosome-like devices. Histogenesis is discussed, and support for a schwannian origin is presented.
D003537:Cystadenoma / Q000473:pathology; D003713:Dendritic Cells / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000473:pathology; D008544:Melanocytes / Q000648:ultrastructure; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D009508:Nevus, Pigmented / Q000032:analysis / Q000648:ultrastructure*; D010051:Ovarian Neoplasms / Q000473:pathology; D009418:S100 Proteins / Q000032:analysis; D002583:Uterine Cervical Neoplasms / Q000032:analysis / Q000648:ultrastructure*
D009363:Neoplasm Proteins; D009418:S100 Proteins