title: Effects of one-week lithium treatment on skilled performance, information processing, and mood in healthy volunteers.
abstract: In a double-blind study, effects of lithium on skilled performance, information processing, and mood were studied in 12 healthy men. Lithium was administered for 1 week and the average, steady state, serum lithium concentration on the morning of testing was 0.8 mEq/liter. Lithium had a non-specific, minor, but consistent effect of prolonging reaction times. Most subjects reported increased anxiety, faintness-dizziness, nervousness-shakiness, and feeling "blue" during and immediately after lithium treatment.
mesh_terms: D000328:Adult; D000339:Affect / Q000187:drug effects*; D001143:Arousal / Q000187:drug effects*; D001288:Attention / Q000187:drug effects*; D006801:Humans; D008094:Lithium / Q000494:pharmacology*; D008297:Male; D004856:Postural Balance / Q000187:drug effects; D011597:Psychomotor Performance / Q000187:drug effects*; D014796:Visual Perception / Q000187:drug effects*
chemical_list: D008094:Lithium