title: Comparison of low-osmolar contrast media in paediatric cardiac angiography.
abstract: Sixty-two children investigated by cardiac angiography for a wide spectrum of congenital heart disease were randomly assigned to one of two groups, one for iohexol, 350 mg I/ml (Omnipaque, Nycomed UK Ltd) and one for iopamidol, 370 mg I/ml (Niopam, E. Merck Ltd). Changes in systolic pressure, end-diastolic pressure when the injection was made into a ventricle, heart rate and rhythm and plasma osmolality were assessed at 1 min and 3 min after the injection of contrast medium. The angiograms were subjectively assessed for angiographic quality. No significant differences were detected between the two groups.
mesh_terms: D000790:Angiocardiography / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007472:Iohexol; D007479:Iopamidol; D009994:Osmolar Concentration; D011897:Random Allocation
chemical_list: D007472:Iohexol; D007479:Iopamidol