[Effect of experimental acute ischemia on capillary-neuro-muscular relations].
Ultrastructural changes in myofibrils, their supplying hemocapillaries, and motor nerve endings were studied in 24 dogs with the experimental acute circulatory ischemia induced by injury to the major arteries of the limbs or tourniquet application for 2, 4, 6, and 9 hours, as well as during the blood stream restoration. Structural rearrangements of myofibrils, capillaries, and axomuscular synapses were found to be simultaneous and depend on the severity of ischemia. Six-hour disruption of the blood flow causes breaking of intracellular homeostatic mechanisms in the soft tissues of the extremities, while a 9-hour ischemia causes irreversible changes in the muscle tissues.
D000208:Acute Disease; D000818:Animals; D002196:Capillaries / Q000648:ultrastructure; D004285:Dogs; D004727:Endothelium / Q000648:ultrastructure; D007511:Ischemia / Q000473:pathology*; D009132:Muscles / Q000098:blood supply* / Q000648:ultrastructure; D009469:Neuromuscular Junction / Q000648:ultrastructure*; D009940:Organoids / Q000648:ultrastructure; D013848:Thigh; D013997:Time Factors
Vliianie ostroĭ ishemii na sostoianie kapilliarno-nervno-myshechnykh otnosheniĭ v éksperimente.