title: The role of interfacial structured water on the glycoprotein arrangement in liposomes.
abstract: The effect of perturbing the interfacial water structure in liposomes on the glycoprotein arrangement in the bilayer was investigated. This perturbation was achieved by a series of reagents called structure makers and breakers. The glycoprotein arrangement in the liposomes was determined by fluorescence measurement with 1-anilino-2-naphthalene sulphonate (ANS). A dependence of (n) (number of binding sites for ANS on the glycoprotein molecule) with concentration of structure maker and breaker reagents was observed. The results have been interpreted as a possible new arrangement of membrane-bound glycoprotein, due to the effect of perturbing the interfacial water structure in the liposomes.
mesh_terms: D000817:Anilino Naphthalenesulfonates; D002784:Cholesterol; D006023:Glycoproteins; D008051:Lipid Bilayers; D008081:Liposomes; D008565:Membrane Proteins; D008744:Methylamines; D010059:Ovomucin; D010713:Phosphatidylcholines; D013050:Spectrometry, Fluorescence; D014508:Urea; D014867:Water
chemical_list: D000817:Anilino Naphthalenesulfonates; D006023:Glycoproteins; D008051:Lipid Bilayers; D008081:Liposomes; D008565:Membrane Proteins; D008744:Methylamines; D010713:Phosphatidylcholines; D014867:Water; D010059:Ovomucin; D014508:Urea; D002784:Cholesterol