title: [Computerized tomography studies in the assessment of radiogenic pneumopathy in an animal experiment].
abstract: An animal experimental study was conducted in 56 piglets exposed to radiation to establish new assessment criteria on radiogenic pneumopathy by employing computed tomography for diagnosis. The accurately measurable density changes in the lung parenchyma exposed to radiation appear invariably as soon as a dose-dependent threshold value is exceeded. Tolerance limits can be determined for 60Co and neutron irradiation in different fractions and single doses, the enhancement of lung density being correlated with the irradiation dose. It is not possible to establish a volume-dependent decrease in the tolerance dose. Likewise, there is no radiation-promoted co-reaction of adjacent pulmonary tissue not subjected to irradiation exposure. These results apply to the experimental animals used in the study.
mesh_terms: D000818:Animals; D003037:Cobalt Radioisotopes / Q000009:adverse effects; D004307:Dose-Response Relationship, Radiation; D008168:Lung / Q000000981:diagnostic imaging / Q000528:radiation effects*; D009502:Neutrons; D011833:Radiation Injuries, Experimental / Q000000981:diagnostic imaging*; D013552:Swine; D014057:Tomography, X-Ray Computed
chemical_list: D003037:Cobalt Radioisotopes
vernacular_title: Computertomographische Untersuchungen zur Erfassung der radiogenen Pneumopathie im Tierexperiment.