[AIDS in children. Histopathologic study of 12 cases].
The anatomo-clinical investigation of a series of 12 cases of AIDS in infants, over two years in Hôpital des Enfants Malades (Paris) allows the following observations to be made: the frequency of materno-foetal contaminations (8/12); the relative shortness of the incubation period (3-6 months); the variable degree of the atrophy of the lymphoid tissues; the absence of vascular proliferation; the interest of demonstrating viral proteins associated with LAV virus (p 18) in imprecisely identifiable cells of lymphoid tissue; the severity of the thymic alterations, which are characterized less by a lymphocyte depletion than by a loss of the maturation of the epithelial tissue, which still preserves its hormone secretory properties.
D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology* / Q000635:transmission; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013950:Thymus Gland / Q000473:pathology; D065227:Transfusion Reaction
Le SIDA chez l'enfant. Etude histopathologique de 12 observations.