Improved production of high-affinity antisera to progesterone by castration and adrenalectomy of the immunised animals.
The titre and affinity of antisera to progesterone were increased by ablation of the progesterone-secreting organs of immunised rats. The animals were maintained for several months following castration and adrenalectomy by daily fludrocortisone.
D000315:Adrenalectomy; D000818:Animals; D007106:Immune Sera / Q000302:isolation & purification; D007114:Immunization; D008297:Male; D009919:Orchiectomy; D011374:Progesterone / Q000276:immunology*; D051381:Rats
D007106:Immune Sera; D011374:Progesterone