Decreased supportive function of platelets from patients with SLE on human endothelial cells.
Platelets show a supportive effect on human endothelial cells in culture. Platelets of patients with systemic lupus erythematosus showed a significantly reduced growth stimulation as demonstrated by reduced DNA synthesis of the endothelial cells.
D001792:Blood Platelets / Q000502:physiology*; D002455:Cell Division; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis; D004727:Endothelium / Q000503:physiopathology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood*
D004247:DNA