[Cytogenetics of human gametes: its application to the study of fertilization anomalies].
A study of 100 sperm karyotypes from 8 normal subjects was carried out using the technique of in vitro hetero-specific human-hamster fertilisation. 19 of those showed some abnormality. 17% of those were hyperploidies or hypoploidies and 2% showed structural abnormalities. A study carried out at the same time on 34 hamster egg karyotypes showed 6 hypoploidies and 1 hyperploidy. In effect oa cytogenetic technique which is very similar to this one makes it possible to analyse the human oocyte karyotype. The results found in these samples of motile sperms show a higher incidence of abnormality than in other published series, but these figures can not be extrapolated to the composition of in vivo whole sperms.
D000818:Animals; D002871:Chromosome Banding; D002877:Chromosomes, Human / Q000032:analysis*; D006224:Cricetinae; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D007621:Karyotyping; D008297:Male; D008647:Mesocricetus; D009865:Oocytes / Q000002:abnormalities* / Q000032:analysis; D011003:Ploidies; D013094:Spermatozoa / Q000002:abnormalities* / Q000032:analysis
La cytogénétique des gamètes humains: application à l'étude des anomalies de la fécondation.