title: Proteoglycans from human articular cartilage: the effect of joint location on the structure.
abstract: Proteoglycan monomers from the articular cartilages of the knee, hip and shoulder of 3 subjects (21, 26 and 45 years old) were isolated and analysed. The proteoglycan monomers from the high weight-bearing knee and hip joints were smaller than those from the low weight-bearing shoulder joints and both had a lower chondroitin sulphate content. The proteoglycan monomers from knee joint cartilage had the lowest intra-individual chondroitin-4-sulphate content in each case. Hyaluronate binding capacity was not found to be dependent on joint location.
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D002358:Cartilage, Articular / Q000032:analysis*; D006025:Glycosaminoglycans / Q000032:analysis; D006621:Hip Joint; D006801:Humans; D007719:Knee Joint; D008875:Middle Aged; D009928:Organ Specificity; D011509:Proteoglycans / Q000032:analysis*; D012785:Shoulder Joint
chemical_list: D006025:Glycosaminoglycans; D011509:Proteoglycans