title: Fine structural characteristics of neurophysin-positive perivascular plexus that develop in the rat hypothalamus following interruption of the hypothalamo-neurohypophysial tract.
abstract: Transection of neurosecretory axons of the hypothalamo-neurohypophysial tract within the hypothalamus by stereotactic grafts of various tissues or knife cuts induced the development of neurophysin-positive plexus around arterioles, venules and capillaries in the vicinity of these grafts or cuts. These plexus ranged from single axons to densely woven networks and tended to increase progressively with time after experimental intervention. At the fine structural level, typical neurosecretory axon profiles were either abutting the perivascular connective tissue space or located within it. They were usually accompanied by astrocyte processes or microglial cells. Many of these axons had extensive contact with the surrounding basal lamina at which point clusters of microvesicles reminiscent of axon terminals in the neural lobe were present.
mesh_terms: D000818:Animals; D001160:Arterioles / Q000648:ultrastructure; D001369:Axons / Q000648:ultrastructure; D002196:Capillaries / Q000648:ultrastructure; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D007031:Hypothalamus / Q000098:blood supply / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D009416:Nerve Regeneration; D009474:Neurons / Q000648:ultrastructure*; D009481:Neurophysins / Q000032:analysis*; D051381:Rats; D014699:Venules / Q000648:ultrastructure
chemical_list: D009481:Neurophysins