Fibroadenoma of the female breast with multinucleated giant cells.
A fibroadenoma in the female breast is described, which contained multiple multinucleated giant cells within the stroma. The investigation indicated the giant cells to be of epithelial nature, caused by epithelial degeneration secondary to myoepithelial swelling of unknown cause. Their presence and morphology could cause anxiety about malignancy, but this was found groundless.
D000232:Adenofibroma / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008408:Mastectomy; D008854:Microscopy, Electron