[Quantitative variations of lymphocyte subsets in various kinds of cancer patients in the terminal stage].
Immunological studies of the peripheral blood were made in terminal breast cancer and terminal abdominal cancer patients. Two immunological parameters were studied: (1) lymphocyte subsets and (2) proliferative response to PHA. A decrease in the number of OKT-3(+) cells and an increase in that of OKT-8(+) cells were observed in abdominal cancer. It was suggested that the immunological status in abdominal cancer is more suppressive than in breast cancer. Increases in the number of OK-M1(+) cells and Leu-7(+) cells were observed in breast cancer. It is suggested that cytotoxic lymphocytes increase in number in breast cancer more than in abdominal cancer.
D001943:Breast Neoplasms / Q000276:immunology*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000276:immunology*; D006801:Humans; D008113:Liver Neoplasms / Q000276:immunology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000145:classification*; D008297:Male; D010051:Ovarian Neoplasms / Q000276:immunology; D010190:Pancreatic Neoplasms / Q000276:immunology; D012004:Rectal Neoplasms / Q000276:immunology; D013274:Stomach Neoplasms / Q000276:immunology