title: [Method for the experimental study of factors modifying carcinogenesis].
abstract: Research in factors modifying carcinogenesis is closely associated with studies on complex multifactorial systems. Mathematical methods of planning multifactorial experiments should be used which assures a higher reliability of the results and elicits additional information. An analysis of the data on the modifying effect of aniline, sodium alkylsulfate and lead nitrite on nitrosomethylamine-induced carcinogenesis carried out on the basis of the newly-developed method showed its advantages over the existing ones.
mesh_terms: D000814:Aniline Compounds / Q000633:toxicity; D000818:Animals; D004128:Dimethylnitrosamine / Q000633:toxicity; D004347:Drug Interactions; D005233:Fatty Alcohols / Q000633:toxicity; D007854:Lead / Q000633:toxicity; D008722:Methods; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000453:epidemiology; D009566:Nitrates / Q000633:toxicity; D012044:Regression Analysis; D012107:Research Design; D013464:Sulfuric Acids / Q000633:toxicity
chemical_list: D000814:Aniline Compounds; D005233:Fatty Alcohols; D009566:Nitrates; D013464:Sulfuric Acids; D007854:Lead; C017461:lead nitrate; D004128:Dimethylnitrosamine; C023650:aniline
vernacular_title: O metodike éksperimental'nogo izucheniia faktorov, modifitsiruiushchikh kantserogenez.