title: Regional cerebral blood flow changes associated with ethanol intoxication.
abstract: Regional cerebral blood flow (CBF) was measured via the 133Xenon inhalation technique in 26 healthy volunteers before and 60 minutes after the oral administration of ethyl alcohol or placebo on a double-blind basis. The cerebral blood flow values, corrected for test-retest differences in carbon dioxide showed a significant bilateral increase after ethanol administration. Blood levels of ethanol, estimated with a breath analyser, did not correlate with the CBF changes.
mesh_terms: D000328:Adult; D000435:Alcoholic Intoxication / Q000503:physiopathology*; D001921:Brain / Q000098:blood supply; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004311:Double-Blind Method; D000431:Ethanol / Q000097:blood / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D011897:Random Allocation; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes; D000431:Ethanol