Does the substantia nigra have a cholinergic innervation?
We have studied the distribution of choline acetyltransferase-containing fibres in ferret substantia nigra using immunohistochemistry at the light microscopical level. Positive staining for choline acetyltransferase was not observed in any nigral cell bodies, but was found in a network of fine-calibre, varicose axons, more densely distributed in the zona compacta than the zona reticulata.
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D002795:Choline O-Acetyltransferase / Q000378:metabolism*; D002799:Cholinergic Fibers / Q000166:cytology*; D005289:Ferrets; D013378:Substantia Nigra / Q000166:cytology* / Q000201:enzymology
D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase