title: [Changes in the peripheral blood of workers engaged in ethylbenzene-styrene and synthetic rubber and latex manufacture].
abstract: A total of 67 workers were examined from the production of "Ethyl benzene-styrene" and 184 workers from the production of "Synthetic rubber and latex", as well as a control group of 59 employees. The workers from the first production are exposed to the effect of styrene, ethyl benzene and toluene. The concentrations of the substances surpass MAC, with several times, at the majority of the working places. The workers with a length of service over 10 years predominate. The workers from the second production are exposed to the combined effect of styrene and divinyl, their concentrations fluctuating from 2 to 8 times over MAC. The workers with a length of service over 10 years are 71.7%. The deviations, established in the hematological indices studied are compared with the results from a study on the workers from those productions of 6 years ago. Dynamics in the changes was established among the workers from the production of "Synthetic rubber and latex", associated with the duration of occupational exposure to styrene and divinyl. In case of a shorter length of service, the deviations are functional (reduction of peroxidase activity in granulocytes), increase of hemoglobin and hematocrit, associated with the adaptive reaction of organism. Pronounced anemic syndrome was established in a considerable number (24 workers) after an exposure of 10 years as well as lymphocytosis (35 subjects) and leukopenia (9 subjects).
mesh_terms: D000041:Absenteeism; D001555:Benzene Derivatives / Q000009:adverse effects*; D001769:Blood / Q000187:drug effects*; D002031:Bulgaria; D002617:Chemical Industry; D005260:Female; D006402:Hematologic Diseases / Q000097:blood / Q000139:chemically induced; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000097:blood / Q000139:chemically induced; D012408:Rubber / Q000009:adverse effects*; D013343:Styrenes / Q000009:adverse effects*
chemical_list: D001555:Benzene Derivatives; D013343:Styrenes; D012408:Rubber; C004912:ethylbenzene
vernacular_title: Promeni v perifernata krŭv na rabotnitsi ot proizvodstvota "Etilbenzol-stirol" i "Sintetichen kauchuk i lateksi".