[Effect of emotional stress on the contractility, adrenoreactivity and calcium sensitivity of smooth muscles of the portal vein in spontaneously hypertensive rats].
The emotional stress decreased contractility and adrenoreactivity in normotensive rats, while in spontaneously hypertensive rats (SHR) the changes were less pronounced. The changes in adrenoreactivity, as well as increased permeability of smooth muscle cells for calcium and reduced reactivity to exogenous calcium revealed in hypertensive animals contribute to high resistance of portal vein smooth muscles to stress.
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology; D009119:Muscle Contraction / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000503:physiopathology*; D011169:Portal Vein / Q000187:drug effects / Q000503:physiopathology; D051381:Rats; D011918:Rats, Inbred SHR / Q000502:physiology*; D011919:Rats, Inbred Strains / Q000502:physiology*; D011921:Rats, Inbred WKY; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000502:physiology*; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000150:complications / Q000503:physiopathology*
D011941:Receptors, Adrenergic; D002118:Calcium
Vliianie émotsional'nogo stressa na sokratimost', adrenoreaktivnost' i chuvstvitel'nost' k kal'tsiiu gladkikh myshts vorotnoĭ veny spontanno gipertenzivnykh krys.