title: Pathology of canine lentiginosis profusa.
abstract: Lentiginosis profusa was diagnosed in 3 pedigree Pugs namely two unrelated parents and their female offspring. Macroscopically the lentigines appeared as black macules up to 10 mm in diameter and occurred especially in the skin of the ventral parts of the body. Skin biopsies revealed localised acanthosis and hyperkeratosis with prominent rete ridges and epidermal hyperpigmentation in the absence of any other significant dermal pathology.
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004817:Epidermis / Q000473:pathology; D005260:Female; D007911:Lentigo / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D008297:Male