[Acute granulomatous interstitial nephritis and hepatitis caused by drugs. Possible role of an allopurinol-furosemide combination].
Acute granulomatous interstitial nephritis and acute granulomatous hepatitis were simultaneously observed in the same patient. Clinical and anamnestic arguments suggest that allopurinol could be responsible for this double localization, but a possible part played by furosemide cannot be excluded. The patient spontaneously recovered without corticosteroid therapy. Such an acute drug induced association did not have been proved so far.
D000208:Acute Disease; D000493:Allopurinol / Q000009:adverse effects; D001262:Atenolol / Q000627:therapeutic use; D001706:Biopsy; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000209:etiology* / Q000473:pathology; D005260:Female; D005665:Furosemide / Q000009:adverse effects; D006099:Granuloma / Q000139:chemically induced* / Q000150:complications; D006801:Humans; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000150:complications
D001262:Atenolol; D000493:Allopurinol; D005665:Furosemide
Néphrite interstitielle et hépatite aiguës granulomateuses d'origine médicamenteuse. Rôle possible de l'association allopurinol-furosémide.