[Effects of enflurane and halothane on hepatic function in biliary surgery].
The effects of two volatile anaesthetics on hepatic function are compared in 80 patients in hepato-biliary surgery. 40 patients were anaesthetized either with enflurane or halothane. This study is based on the variations of blood levels of gamma GT, bilirubin, SGOT SGPT, alkaline phosphatase, L.D.H. Samples were taken the day prior to the operation, one, two and five days afterwards. The results show an increase in the levels of BD, SGPT, LDH no 5, less important with enflurane than with halothane, and mainly in patients with preoperative hepatic abnormalities. Enflurane appears to be preferable in such cases.
D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D000769:Anesthesia, Inhalation; D001660:Biliary Tract Diseases / Q000097:blood* / Q000601:surgery; D001663:Bilirubin / Q000097:blood; D004737:Enflurane / Q000494:pharmacology*; D005260:Female; D006221:Halothane / Q000494:pharmacology*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008099:Liver / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014166:Transferases / Q000097:blood
D004737:Enflurane; D007770:L-Lactate Dehydrogenase; D014166:Transferases; D000469:Alkaline Phosphatase; D001663:Bilirubin; D006221:Halothane
Effets de l'enflurane et de l'halothane sur la fonction hépatique en chirurgie biliaire.