[Spike activity of neurons of the ventromedial hypothalamus of the rabbit in response to cholecystokinin application to the cornea].
Microapplication to the rabbit eye cornea of the [Glu26] analogue of nonsulphated C-terminal octapeptide cholecystokinin reduced 2-5-fold the firing rate of the ventromedial hypothalamus neurons whereas [Glu26, 32] induced a 2-3-fold increase of the firing rate. Contralateral application increased 1.2-2.3-fold the latencies of responses. Nonsulphated C-terminal octapeptide cholecystokinin, its analogue [Glu32] and 0.9% NaCl solution exerted no obvious effect.
D000200:Action Potentials; D000818:Animals; D002682:Chinchilla; D003315:Cornea / Q000187:drug effects*; D008297:Male; D012844:Sincalide / Q000031:analogs & derivatives / Q000494:pharmacology*; D014697:Ventromedial Hypothalamic Nucleus / Q000502:physiology*
D012844:Sincalide
Impul'snaia aktivnost' neĭronov ventromedial'nogo gipotalamusa krolika pri applikatsii na rogovitsu glaza kholetsistokinina.