title: Paternity testing 3: exclusion probabilities.
abstract: Blood typing with several blood systems is used in many countries to determine paternity or nonpaternity with respect to an alleged father. Various probabilities are usually presented, in particular: the conditional probability of excluding a random man as father given a particular mother-child phenotype combination, and the expected (unconditional) exclusion probability for all mother-child combinations can be calculated for a given blood system. Because these probabilities are of general interest in paternity studies, explicit formulae for the unconditional probabilities have been derived for some of the systems. Algorithms suitable for a microcomputer are given here for finding the exclusion probabilities for any system. These algorithms avoid the need for developing new formulae whenever a new system is introduced or a current system is extended through the addition of further alleles.
mesh_terms: D000465:Algorithms; D001789:Blood Group Antigens / Q000235:genetics; D001788:Blood Grouping and Crossmatching; D002648:Child; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D010334:Paternity; D010641:Phenotype; D011336:Probability
chemical_list: D001789:Blood Group Antigens