[Thrombocyte aggregation in the plasma and whole blood and ATP secretion during hypoxia in cats].
Platelet aggregation in platelet rich plasma and whole blood, as well as ATP secretion were studied during hypoxia in cats. A significant inhibition of collagen-induced aggregation in plasma and whole blood and ADP-induced aggregation in plasma alone with a parallel decrease of platelet ATP secretion were demonstrated. The data obtained are indicative of an important modulatory role of eicosanoids in the vascular wall interaction during hypoxia with a possible involvement of thromboxane A2.
D000136:Acid-Base Equilibrium; D000244:Adenosine Diphosphate / Q000494:pharmacology; D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D002415:Cats; D003094:Collagen / Q000494:pharmacology; D000860:Hypoxia / Q000097:blood*; D010949:Plasma / Q000502:physiology*; D010974:Platelet Aggregation / Q000187:drug effects
D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D003094:Collagen
Agregatsiia trombotsitov v plazme i tsel'noĭ krovi i sekretsiia ATF v usloviiakh gipoksii u koshek.