[Antipneumococcal vaccination: comparison between vaccines].
Fourteen antigen and 17 antigen polyvalent vaccines against Str. pneumoniae have been tested on 137 healthy volunteers. They have been shown to cause side-effects infrequently. A two-fold or higher increase of antibody concentration (detected by RIA) has been demonstrated in 80% of the vaccinees against all antigens of the 17 valent vaccine; while such increase has been demonstrated only for 12 out of 14 antigens in the other vaccine (for the other two antigens the percentages have been 66.7% (antigen 1) and 73.7% (antigen 12F). It is stressed that the use of these vaccines is particularly recommended for the prevention of pneumococcal diseases in higher risk subjects.
D000907:Antibodies, Bacterial / Q000276:immunology*; D006801:Humans; D011008:Pneumococcal Infections / Q000276:immunology / Q000517:prevention & control*; D014611:Vaccination
D000907:Antibodies, Bacterial
Vaccinazione antipneumococcica: confronto fra vaccini.