B antigen acquired by normal A1 red cells exposed to a patient's serum.
The authors report a patient with the acquired B antigen whose serum contained a factor capable of inducing the acquired B phenotype on normal A1 red cells in vitro. The patient's red cells were not, however, agglutinated by a monoclonal anti-B. These findings and the abolition of the acquired B antigen by treatment of the patient's red cells with acetic anhydride support the deacetylation theory of the genesis of the acquired B antigen.
D000017:ABO Blood-Group System / Q000276:immunology*; D000107:Acetylation; D000368:Aged; D000911:Antibodies, Monoclonal; D002240:Carbohydrate Sequence; D004912:Erythrocytes / Q000276:immunology*; D006384:Hemagglutination; D006801:Humans; D008297:Male
D000017:ABO Blood-Group System; D000911:Antibodies, Monoclonal