Angiographic evidence of basilar artery constriction in the rabbit: a new model of vasospasm.
The main objective of this study was to produce angiographic evidence of basilar artery constriction using the rabbit model. The technique described involves the transdural injection of blood into the cisterna magna on two different days. The results obtained show that vasoconstriction occurs over a time period that is comparable in duration to that seen in patients undergoing vasospasm as a result of subarachnoid hemorrhage. Further investigation should be done to evaluate the usefulness of the rabbit model as a verifiable tool in studying the etiology of vasospasm.
D000818:Animals; D002533:Cerebral Angiography; D003251:Constriction, Pathologic; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging*; D011817:Rabbits; D014715:Vertebrobasilar Insufficiency / Q000000981:diagnostic imaging* / Q000401:mortality