title: The effects of Plagiorchis noblei metacercariae on the development and survival of Aedes aegypti larvae in the laboratory.
abstract: Plagiorchis noblei infections impair the survival and development of fourth instar Aedes aegypti larvae. Mortality during the larval and pupal stages reached 92%, and 60% of the emerging adults were malformed. The metacercariae interfere with pupation and the emergence of adults. Larvae and pupae that fail to transform to the next developmental stage within the normal time characteristically persist for extended periods, but invariably die without transforming. Whereas 82% of the control larvae gave rise to functional adults, only 4% of infected larvae managed to do so. Such effects may facilitate the transmission of the parasite.
mesh_terms: D000330:Aedes / Q000254:growth & development / Q000469:parasitology*; D000818:Animals; D006790:Host-Parasite Interactions; D007814:Larva / Q000254:growth & development / Q000469:parasitology; D011679:Pupa / Q000254:growth & development / Q000469:parasitology; D014200:Trematoda / Q000502:physiology*