title: [A stepwise method of evaluating sugar substitutes--a preliminary study using enzymes. 3. Carbohydrases from the human jejunal mucosa].
abstract: Mixed carbohydrases from human jejunal mucosa were characterized by Michaelis constants and maximal velocities of hydrolysis of 15 disaccharides and disaccharide alcohols, mainly of the glucosylfructose series. The presumed fate of such substances after oral ingestion may be foreseen from the km and vmax data. There is principal agreement that wholesomeness in man and animals as well as energetic utilization of disaccharides and split products correlate well with the enzymological data. Therefore the metabolic fate of sugar substitutes in the human body is partially predictable from such enzymic studies.
mesh_terms: D004186:Disaccharidases / Q000378:metabolism; D004187:Disaccharides / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D007413:Intestinal Mucosa / Q000201:enzymology*; D007583:Jejunum / Q000201:enzymology*; D013549:Sweetening Agents / Q000378:metabolism*
chemical_list: D004187:Disaccharides; D013549:Sweetening Agents; D004186:Disaccharidases; D006026:Glycoside Hydrolases; C019822:carbohydrase
vernacular_title: Stufenweises Prüfschema für Zuckeraustauschstoffe--Vorprüfung mittels Enzymen. 3. Carbohydrasen aus Jejunalmucosa des Menschen.