title: Nasal absorption of progesterone in women.
abstract: Absorption profiles were obtained from women following the administration of ointment containing 20, 30 and 40 mg of progesterone to the nasal mucosa. There were no significant differences in area-under-curves between groups receiving the drug in one nostril but when 40 mg doses were divided between two nostrils there was a significantly greater area-under-curve suggesting that the area of mucosa applied with the drug is more important than dosage.
mesh_terms: D000042:Absorption; D000281:Administration, Intranasal; D005260:Female; D006801:Humans; D009297:Nasal Mucosa / Q000378:metabolism*; D011374:Progesterone / Q000008:administration & dosage* / Q000378:metabolism; D013997:Time Factors
chemical_list: D011374:Progesterone