In vitro metabolism of [3H]NA induced by pargyline in the superior cervical ganglion.
The deaminated glycol, [3H]DOPEG, is the main metabolite in spontaneous outflow from ganglia labelled with [3H]NA. After exposure to pargyline 0.5 mM, [3H]NMN formation may be the first step of the metabolism of [3H]NA in the cat superior cervical ganglion.
D000818:Animals; D002415:Cats; D005260:Female; D005727:Ganglia, Spinal / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000031:analogs & derivatives / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D010293:Pargyline / Q000494:pharmacology*
D008734:Methoxyhydroxyphenylglycol; D010293:Pargyline; C010117:3,4-dihydroxyphenylglycol; D009638:Norepinephrine