[Immune complex binding by erythrocytes and its significance in the destruction of these cells during immunization].
Immunization of BALB/c mice by sheep red blood cells and Salmonella typhi vaccine has been shown to augment the immune complexes in plasma and erythrocytes in blood fixing the immune complexes on their surface. The inactivation of immune complexes in immunized mice by intravenous injection of the antiserum against aggregated immunoglobulins decreases the hemoglobin in blood serum. The data obtained show that the fixation of immune complexes on erythrocytes is one of the reasons of erythrocytes destruction activation in immunization.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000276:immunology / Q000378:metabolism*; D001428:Bacterial Vaccines / Q000276:immunology; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000276:immunology / Q000378:metabolism*; D007106:Immune Sera / Q000276:immunology; D007114:Immunization / Q000379:methods; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D012485:Salmonella typhi / Q000276:immunology; D012756:Sheep; D013997:Time Factors
D000936:Antigen-Antibody Complex; D001428:Bacterial Vaccines; D007106:Immune Sera
Sviazyvanie immunnykh kompleksov éritrotsitami i ego znachenie v destruktsii étikh kletok pri immunizatsii.