[Erythrocyte elastic and mechanical properties and mechanism of their change during irradiation].
A decrease in erythrocyte deformation, which was maximum at the height of radiation sickness, was registered as early as 1-3 days following 6 Gy irradiation of rats. The aggregation of erythrocytes increased during the latent period of radiation sickness then sharply decreased. The role of the observed changes in radiation sickness then pathogenesis is discussed. It is established that they are associated with the altered fatty acid composition of the lipid phase of erythrocytic membranes, on the one hand, and with the disturbances in its ionic permeability, on the other.
D000208:Acute Disease; D000818:Animals; D003037:Cobalt Radioisotopes; D004548:Elasticity; D004903:Erythrocyte Aggregation / Q000528:radiation effects; D004907:Erythrocyte Deformability / Q000528:radiation effects*; D004910:Erythrocyte Membrane / Q000528:radiation effects*; D008051:Lipid Bilayers / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000097:blood; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D003037:Cobalt Radioisotopes; D008051:Lipid Bilayers
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