title: A case of neuroleptic malignant syndrome in a mentally retarded adolescent.
abstract: The neuroleptic malignant syndrome is an uncommon but occasionally fatal reaction to antipsychotic medication characterized by fever, movement disorder, and stupor. A case is reported of a 16-year-old retarded male who progressed into coma after an injection of fluphenazine. The syndrome is discussed, and new pharmacological treatment approaches are reviewed. Brain-damaged patients are thought to be more susceptible to this syndrome. As recognition of the syndrome grows, there may well be more cases identified in the mentally retarded population.
mesh_terms: D000293:Adolescent; D000374:Aggression / Q000187:drug effects; D005476:Fluphenazine / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*
chemical_list: C011825:fluphenazine depot; D005476:Fluphenazine