[Effect of cisplatin on the recovery from sublethal and potentially lethal radiation damage in cell culture].
The effect of Cisplatin upon the recovery from sublethal damage during fractionated irradiation and upon the recovery from potentially lethal damage after a single dose has been investigated. In three mammalian cell lines, Cisplatin did not influence the recovery from sublethal and potentially lethal damage. There were differences among the three cell lines in their ability to recover from radiation damage. However, a significant quantitative difference between the recovery from sublethal and potentially lethal damage in any one cell line could not be found.
D000818:Animals; D002460:Cell Line; D002945:Cisplatin / Q000494:pharmacology*; D003238:Connective Tissue / Q000528:radiation effects*; D003239:Connective Tissue Cells; D006224:Cricetinae; D003412:Cricetulus; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D007668:Kidney / Q000166:cytology / Q000528:radiation effects*; D008545:Melanoma / Q000532:radiotherapy*; D008647:Mesocricetus; D011829:Radiation Dosage; D011879:Radiotherapy Dosage
D002945:Cisplatin
Der Effekt von Cisplatin auf die Erholung vom subletalen und potentiell letalen Strahlenschaden in der Zellkultur.