title: [The role of lipid peroxidation in the process of thermal inactivation of tissue thromboplastin].
abstract: Thermic inactivation of tissue thromboplastin in air led to an increase in concentration of malonic dialdehyde and to decrease in activity of thromboplastin. Thromboplastin, treated with ionol, exhibited a less distinct loss of the hemocoagulation activity on heating. Inactivation of the tissue thromboplastin in air during thermic treatment involved at least three steps: thermic denaturation of apoprotein III, lipid peroxidation of the lipid component, observed in the experiment, oxidation of apoprotein III and destruction of its lipid moiety.
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D002084:Butylated Hydroxytoluene / Q000494:pharmacology; D006358:Hot Temperature; D066298:In Vitro Techniques; D008054:Lipid Peroxides / Q000378:metabolism*; D011817:Rabbits; D013925:Thromboplastin / Q000037:antagonists & inhibitors*
chemical_list: D008054:Lipid Peroxides; D002084:Butylated Hydroxytoluene; D013925:Thromboplastin
vernacular_title: Rol' perekisnogo okisleniia lipidov v protsesse termicheskoĭ inaktivatsii tkanevogo tromboplastina.