Perinatal mortality associated with intrauterine infection due to pseudomonads.
Pseudomonads are common causes of nosocomial infections but are rarely implicated in perinatal disease. In a retrospective autopsy study we found that 9% of all acute congenital bacterial infections were due to Pseudomonas species. Premature rupture of membranes occurred in half the cases and clinical maternal amnionitis in two-thirds. One case was apparently nosocomial in origin. No known risk factors were implicated in any other case. Seven infants were stillborn and two died within a few hours. Congenital pneumonia, funisitis, and chorioamnionitis were found at autopsy. Intrauterine infection due to the pseudomonads poses a serious problem that has not been previously recognized.
D005260:Female; D005313:Fetal Death / Q000209:etiology*; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008297:Male; D011014:Pneumonia / Q000151:congenital / Q000209:etiology; D011247:Pregnancy; D011552:Pseudomonas Infections / Q000151:congenital*; D012189:Retrospective Studies; D018805:Sepsis / Q000151:congenital / Q000209:etiology