title: [Effect of spasmo-analgesics on uterine activity in induced labor].
abstract: On the basis of two randomly selected, independent, clinically and statistically comparable groups of induced labours the influence of a spasmoanalgetic combination of Valium and Dolantin on uterine activity and indirectly on the progression of labour was studied. Each group consisted of nineteen primiparous women differing from one another only by having been or not having been administrated spasmoanalgetics. All the laboures were monitored by the direct method of internal cardiotocography. Uterine activity was manually calculated with planimetrically presented active pressure area (APA). The ratio between the calculated activity in kPa/sec and cervical dilatation in cms resulted in the resistance-gram. Quantitative statistical analysis has shown significantly lower total and average ten-minute uterine activity in the group to which spasmoanalgetics were administered and where there were no changes in the duration of dilatation. Assuming that the total uterine impulse is an indirect index of cervical resistance, it can be concluded that spasmoanalgetics reduce cervical resistance.
mesh_terms: D000328:Adult; D000700:Analgesics / Q000494:pharmacology*; D003975:Diazepam / Q000008:administration & dosage / Q000494:pharmacology*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007751:Labor, Induced; D008614:Meperidine / Q000008:administration & dosage / Q000494:pharmacology*; D011247:Pregnancy; D011446:Prospective Studies; D011897:Random Allocation; D013565:Sympatholytics / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects*
chemical_list: D000700:Analgesics; D013565:Sympatholytics; D008614:Meperidine; D003975:Diazepam
vernacular_title: Utjecaj spazmoanalgetika na aktivnost uterusa u stimuliranom porodu.