title: Nickel dermatitis in infants.
abstract: 8 cases of allergic contact dermatitis to nickel in infants are reported. All showed a papular dermatitis matching the sites of contact. Patch testing was performed on 3 patients, 2 were tested to nickel sulfate in pet. at concentrations of 1.0%, 1.5%, 2.0%. 1 was tested to 2.5% alone. All developed ++ reactions at each concentration tested. We observed a strong association of nickel dermatitis with atopy; 7 of 8 patients had a family history of atopy and 5 of 8 had features of coexistent atopic dermatitis. The relationship between atopy and allergic contact dermatitis is briefly reviewed. Nickel dermatitis may aggravate atopic dermatitis; avoidance of metal contact is crucial in the management of these patients.
mesh_terms: D003876:Dermatitis, Atopic / Q000150:complications / Q000276:immunology; D003877:Dermatitis, Contact / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007223:Infant; D008297:Male; D009532:Nickel / Q000009:adverse effects*; D012882:Skin Tests
chemical_list: D009532:Nickel; D006854:Hydrocortisone