[Subacute necrotizing encephalopathy, Leigh's disease. Apropos of a case].
Leigh's disease is a subacute metabolic encephalopathy characterized by bilateral and symmetrical lesions of basal ganglia, mid-brain and pons. Lesions are related to an abnormal pyruvate metabolism which mechanisms remain still uncertain. This disease is rare and the authors present a case with complete anatomic study.
D001921:Brain / Q000378:metabolism / Q000473:pathology*; D001928:Brain Diseases, Metabolic / Q000473:pathology*; D002675:Child, Preschool; D006801:Humans; D007888:Leigh Disease / Q000473:pathology*; D008297:Male; D008929:Mitochondria, Heart / Q000648:ultrastructure; D009206:Myocardium / Q000473:pathology* / Q000648:ultrastructure; D011773:Pyruvates / Q000378:metabolism; D019289:Pyruvic Acid
D011773:Pyruvates; D019289:Pyruvic Acid
Encéphalopathie nécrosante subaiguë, maladie de Leigh. A propos d'un cas.