Acute renal failure due to cisplatin.
A case of acute renal failure associated with cisplatin therapy for a stage IV neuroepitelioma of the chest wall is described. This case was associated with a normal magnesium concentration and with presence of fibrinogen in the Tubular Basement Membrane and of IgG in the interstitial infiltrates. Immunological activation was evidentiated by fine needle aspiration biopsy (FNAB) at the time of renal biopsy.
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000473:pathology; D001707:Biopsy, Needle; D002648:Child; D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005920:Glomerular Mesangium / Q000473:pathology; D006801:Humans; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000188:drug therapy; D013899:Thoracic Neoplasms / Q000188:drug therapy
D002945:Cisplatin