Absence of effect of 3-amino-1,2,4-triazole pretreatment on blood ethanol levels after oral administration, in rats.
Blood ethanol levels registered in rats receiving 90 mmole/kg by gavage were not different in rats pretreated with aminotriazole (1 g/kg IP) 1 hour before, than in untreated controls. Results are consistent with the idea that no measurable gastrointestinal catalase first pass effect is present in rats.
D000284:Administration, Oral; D000640:Amitrole / Q000494:pharmacology*; D000818:Animals; D000431:Ethanol / Q000008:administration & dosage / Q000097:blood*; D005260:Female; D051381:Rats; D014230:Triazoles / Q000494:pharmacology*
D014230:Triazoles; D000431:Ethanol; D000640:Amitrole