title: [Incretory changes in the pancreatic hormones in chronic pancreatitis].
abstract: Radioimmunoassay was employed to study blood content of insulin, C-peptide and glucagon in 78 patients with chronic pancreatitis. It was revealed that during exacerbation, there was an increase in the content of insulin and glucagon and, to a lesser degree, in that of C-peptide. During remissions, part of the patients showed insular deficiency which increased with disease standing. When pancreatitis lasted from 1 to 5 years or from 5 to 10 years, diabetes mellitus was recorded in 9.4% of the patients and in 16% of the patients, respectively.
mesh_terms: D002096:C-Peptide / Q000097:blood; D002908:Chronic Disease; D005934:Glucagon / Q000097:blood; D006801:Humans; D007330:Insulin Antibodies / Q000032:analysis; D010187:Pancreatic Hormones / Q000378:metabolism*; D010195:Pancreatitis / Q000097:blood*; D011863:Radioimmunoassay; D012008:Recurrence
chemical_list: D002096:C-Peptide; D007330:Insulin Antibodies; D010187:Pancreatic Hormones; D005934:Glucagon
vernacular_title: Izmenenie inkretsii nekotorykh gormonov podzheludochnoĭ zhelezy pri khronicheskom pankreatite.