Reactions of 5-bromo substituted pyrimidine nucleosides with aqueous alkalies: kinetics and mechanisms.
Kinetics for the parallel and consecutive steps of the reactions of 5-bromocytidine, 5-bromouridine and its 5'-O-methyl and 2',3'-O-isopropylidene derivatives with aqueous alkalies were studied by LC. The mechanisms of the partial reactions involved are discussed.
D000468:Alkalies; D000998:Antiviral Agents; D055598:Chemical Phenomena; D002621:Chemistry; D007700:Kinetics; D011741:Pyrimidine Nucleosides; D012996:Solutions; D014867:Water
D000468:Alkalies; D000998:Antiviral Agents; D011741:Pyrimidine Nucleosides; D012996:Solutions; D014867:Water