The redox state in lymphocytes from patients with rheumatoid arthritis.
Our study was designed to quantitate levels of NAD+, NADH, NADP(H), and ATP in peripheral blood lymphocytes with and without mitogenic stimulation from patients with rheumatoid arthritis (RA). No differences were found in patients with RA and healthy controls. Our data suggest the ability of the redox system of circulating peripheral lymphocytes to respond to mitogenic stimulation in patients with RA is not markedly impaired.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000201:enzymology / Q000378:metabolism*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D009243:NAD / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D010084:Oxidation-Reduction; D010835:Phytohemagglutinins / Q000494:pharmacology
D010835:Phytohemagglutinins; D009243:NAD; D009249:NADP; D000255:Adenosine Triphosphate