The relative importance of N-oxidation and N-demethylation in the metabolism of trimethylamine in man.
The metabolism of orally administered trimethylamine has been studied in 4 male volunteers at 2 dose levels. N-Oxidation was the major route of metabolism whilst N-demethylation was negligible and only significant at the higher dose level.
D004123:Dimethylamines / Q000652:urine; D006801:Humans; D008297:Male; D008744:Methylamines / Q000378:metabolism*; D008745:Methylation; D010084:Oxidation-Reduction
D004123:Dimethylamines; D008744:Methylamines; C034516:dimethylamine; C023336:trimethylamine