[Modifying effect of dioxane on the cytogenetic activity of N-nitroso-N-methylurea].
Dry seeds of Crepis capillaris L. were treated with N-nitroso-N-methyl urea (NMU) and with dioxane (DO) an organic solvent, at pH 7.0 and pH 5.7. The treatment with NMU only was used as a positive control. Three concentrations of NMU were applied. The cytogenetic activity of NMU was found to considerably decrease at two values of pH, while NMU was solved in DO. The relationship between different types of chromosome aberrations remained unchanged in this case.
D002869:Chromosome Aberrations / Q000187:drug effects*; D004146:Dioxanes / Q000494:pharmacology*; D004147:Dioxins / Q000494:pharmacology*; D004336:Drug Antagonism; D008770:Methylnitrosourea / Q000633:toxicity*; D009152:Mutagenicity Tests; D009153:Mutagens; D010944:Plants / Q000235:genetics
D004146:Dioxanes; D004147:Dioxins; D009153:Mutagens; D008770:Methylnitrosourea; C025223:1,4-dioxane
Modifitsiruiushchee vliianie dioksana na tsitogeneticheskuiu aktivnost' N-nitrozo-N-metilmocheviny.