Potential long-acting contraceptive agents: esters and ethers of testosterone with alpha- and/or beta-chain branching.
The synthesis of ten esters and two ethers of testosterone (17 beta-hydroxyandrost-4-en-3-one) is described. All these possess some form of alpha - and/or beta - substitution in the ester/ether side-chain. The work was undertaken in order to evaluate the long-acting antifertility effect of such compounds in males.
D055598:Chemical Phenomena; D002621:Chemistry; D003272:Contraceptive Agents, Male / Q000138:chemical synthesis*; D004952:Esters; D004987:Ethers; D013739:Testosterone / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D003272:Contraceptive Agents, Male; D004952:Esters; D004987:Ethers; D013739:Testosterone