Charcoal hemoperfusion treatment of severe theophylline toxicity.
A 38 year old man was admitted eight hours after taking ten grams of theophylline. The plasma concentration of theophylline on admission was 732 mumol/l. In view of the patient's continuing clinical deterioration, charcoal hemoperfusion was undertaken. This led to a rapid fall in plasma theophylline concentrations and improvement in clinical signs. It is suggested that charcoal hemoperfusion has a role in the severely theophylline toxic patient in whom standard conservative measures are failing. The patient's hyperglycemia, metabolic acidosis, and hypokalemia are discussed.
D000328:Adult; D002606:Charcoal; D006464:Hemoperfusion; D006801:Humans; D006943:Hyperglycemia / Q000139:chemically induced; D007008:Hypokalemia / Q000139:chemically induced; D008297:Male; D013806:Theophylline / Q000097:blood / Q000506:poisoning*
D002606:Charcoal; D013806:Theophylline