Eosinophilic granulocyte deficiency in mice mutant in sl and w loci.
Homozygous Sl/Sl and Wv/Wv mice were found to have approximately 15% of the normal number of circulating eosinophils. Furthermore, these mice exhibited reduced numbers of eosinophilic granulocytes in the bone marrow, spleen and thymus as compared to littermate control normal mice.
D000367:Age Factors; D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D004804:Eosinophils; D005260:Female; D007958:Leukocyte Count; D007970:Leukopenia / Q000097:blood / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains / Q000097:blood*; D012376:Rodent Diseases / Q000097:blood / Q000235:genetics* / Q000473:pathology; D012737:Sex Factors; D013154:Spleen / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology