A primate model for producing experimental alveolar cleft defects.
A simplified surgical technique to create an alveolar cleft defect with oronasal communication was developed in 12 female rhesus monkeys. The defects fulfilled the following criteria: 1) a bilateral alveolar cleft with a minimal width of 1 cm; 2) presence of an oronasal communication lined by epithelium; 3) absence of any clinical signs of inflammation within the cleft defect area; and 4) presence of functional teeth on each side of the created defect.
D000180:Acrylic Resins; D000539:Alveolar Process / Q000002:abnormalities*; D000541:Alveolectomy / Q000379:methods*; D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D007442:Intubation, Intratracheal / Q000295:instrumentation; D008253:Macaca mulatta; D009957:Oroantral Fistula / Q000601:surgery; D010159:Palate / Q000601:surgery; D014081:Tooth Extraction
D000180:Acrylic Resins