[Intrathecal morphine administration in pain therapy following extensive gynecologic operations. Clinical study].
Experiences with intrathecal morphine analgesia in 36 patients undergoing Wertheim-Held hysterectomy are reported. Postoperative painrelief, bloodgas-parameters (pO2, pCO2, pH, SBE, SAT), analgetica demand, side-effects are compared with 23 patients of a control group. 95% of patients with intrathecal morphine analgesia were postoperatively without pain for at least 24 hours. The postoperative demand of analgetic drugs could be reduced to less than 50% in the first 48 postoperative hours. Besides not significant decreasing of the pH-value no changing of the bloodgases was observed. The incidence of nausea, vomiting and headache were not increased. Considering the not in all cases avoidable development of a respiration insufficiency even after a little dosis of morphine this method seems to be a suitable treatment of postoperative pain which enables the early mobilisation of the patients.
D000328:Adult; D000368:Aged; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007278:Injections, Spinal; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage* / Q000009:adverse effects; D010149:Postoperative Pain / Q000188:drug therapy*
D009020:Morphine
Intrathekale Morphinapplikation zur Schmerztherapie nach ausgedehnten gynäkologischen Operationen. Klinische Studie.