[Clinical significance of the determination of serum carbohydrate antigen 19-9 in patients with carcinoma of the stomach and colorectum].
Serum CA 19-9 levels were measured in 68 gastric cancer patients and 38 cases of colorectal cancer. In patients with stage I-III gastric cancer or Duckes A-C colorectal cancer, the CA 19-9 levels ranged from normal to 127 U/ml, whereas in more advanced cases it was very high. Classified by the mode of recurrence, the highest level of CA 19-9 was observed in liver metastasis. After removal of the main tumor, the CA 19-9 level declined rapidly, increasing with recurrence. Serum CA 19-9 determination in cases of gastric or colorectal cancer was useful to classify the stage of disease, developing a prognosis and identifying a recurrence.
D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003110:Colonic Neoplasms / Q000276:immunology* / Q000601:surgery; D006801:Humans; D009363:Neoplasm Proteins / Q000032:analysis; D009367:Neoplasm Staging; D010455:Peptides / Q000032:analysis; D011184:Postoperative Period; D011379:Prognosis; D012004:Rectal Neoplasms / Q000276:immunology* / Q000601:surgery; D013274:Stomach Neoplasms / Q000276:immunology* / Q000601:surgery; D019396:Tissue Polypeptide Antigen
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen; D009363:Neoplasm Proteins; D010455:Peptides; D019396:Tissue Polypeptide Antigen; C030193:immunosuppressive acidic protein