Intrauterine conversion of fetal supraventricular tachycardia with combination of digoxin and verapamil.
A case of fetal supraventricular tachycardia (SVT) diagnosed by fetal echocardiography at 31 weeks gestation and successfully converted in utero is reported. Administration of digoxin orally to the mother resulted in very brief periods of normal fetal cardiac rhythm. Intravenous administration of verapamil to the mother resulted in sustained conversion to normal fetal sinus rhythm. Maintenance therapy with oral digoxin and verapamil was given to the mother for the remainder of the pregnancy with no recurrence of the fetal arrhythmia.
D000284:Administration, Oral; D000328:Adult; D004077:Digoxin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D004452:Echocardiography; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D007275:Injections, Intravenous; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D013610:Tachycardia / Q000175:diagnosis / Q000188:drug therapy*; D014700:Verapamil / Q000008:administration & dosage*
D004077:Digoxin; D014700:Verapamil