Acute leukaemia following malignant ependymoma: a case report.
Though an increasing number of chemotherapy- and radiotherapy-related leukaemias are being reported, acute promyelocytic leukaemia developing as a therapy-related second malignancy is still uncommon. Here we report a case of acute promyelocytic leukemia, microgranular variant, developing in a case of intracranial malignant ependymoma, 1.5 years following treatment with craniospinal radiotherapy.
D000293:Adolescent; D001932:Brain Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D004806:Ependymoma / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000209:etiology* / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects