[Computerized tomography in the evaluation of neurologic complications of preventive therapy of acute lymphatic leukemia].
The authors examined by means of computed tomography 12 patients with ALL treated with radiotherapy combined with cytostatic chemotherapy and presenting clinical signs of CNS damage. The CT scan findings are correlated with clinical signs, mainly distinguishing between symptoms of either diffuse or focal damage. An attempt is made in order to evaluate the possible role of Methotrexate and X-Ray therapy in the pathogenesis of the CNS lesions.
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D002114:Calcinosis / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D007945:Leukemia, Lymphoid / Q000628:therapy*; D008727:Methotrexate / Q000009:adverse effects; D019965:Neurocognitive Disorders / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D008727:Methotrexate
La tomografia computerizzata nella valutazione delle complicanze neurologiche della terapia profilattica della leucemia linfatica acuta.