Automated measurement of multivariate locomotor behavior in rodents.
Most automated methods of monitoring locomotion in animals have used mechanical equipment which measure only one dependent variable and are quite susceptible to a variety of experimental errors. Computer technology has advanced the mechanical means of measuring locomotor activity, allowing a new capability for simultaneously recording many aspects of locomotion. For example, the Digiscan System measures over 20 different indices of ambulatory, rearing, stereotypical and rotational behaviors over real time. Although standardization of some of these techniques is still needed, the computerized approach has already proven itself of value in neurobehavioral research. This paper describes the use of commercial systems in research.
D000818:Animals; D001388:Aziridines / Q000494:pharmacology; D002794:Choline / Q000031:analogs & derivatives / Q000494:pharmacology; D003342:Corpus Striatum / Q000187:drug effects; D003913:Dextroamphetamine / Q000494:pharmacology; D004195:Disease Models, Animal; D005010:Ethology / Q000379:methods*; D006801:Humans; D006948:Hyperkinesis; D008297:Male; D008746:Methylazoxymethanol Acetate / Q000494:pharmacology; D009043:Motor Activity; D011600:Psychopharmacology / Q000379:methods*; D051381:Rats; D011919:Rats, Inbred Strains; D012601:Scopolamine / Q000494:pharmacology; D013239:Stereotyped Behavior
D001388:Aziridines; D008746:Methylazoxymethanol Acetate; C044894:ethylcholine aziridinium; D012601:Scopolamine; D002794:Choline; D003913:Dextroamphetamine