Proposed disk diffusion susceptibility criteria for ofloxacin.
Disk diffusion zone diameter breakpoint criteria for ofloxacin were tentatively established by correlating MICs with 1-, 3-, and 5-micrograms disk inhibitory zone diameters for 638 bacterial isolates representing 36 species. We recommend use of 5-micrograms disks with the following breakpoints: susceptible (MIC, less than or equal to 2.0 micrograms/ml), greater than or equal to 16 mm; intermediate (MIC, 4.0 micrograms/ml), 13 to 15 mm; and resistant (MIC, greater than or equal to 8.0 micrograms/ml), less than or equal to 12 mm.
D000900:Anti-Bacterial Agents; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D015242:Ofloxacin; D010078:Oxazines / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D010078:Oxazines; D015242:Ofloxacin