Penitricin, a new class of antibiotic produced by Penicillium aculeatum. IV. Biosynthesis.
Bioconversion experiments using washed mycelia of Penicillium aculeatum NR 5165 and NR 6216 revealed that penitricin (Ro 09-0804, hydroxymethylcyclopropenone) was biosynthesized from trans-2-butene-1,4-diol via 4-hydroxycrotonaldehyde.
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D003470:Culture Media; D003521:Cyclopropanes / Q000096:biosynthesis; D010407:Penicillium / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D003470:Culture Media; D003521:Cyclopropanes; C042542:penitricin