Dietary manipulation of postprandial colonic lactose fermentation: I. Effect of solid foods in a meal.
The effect of adding solid foods--cornflakes, banana and hard-boiled egg--to a meal with 360 ml of intact milk containing 18 g of lactose was investigated in 13 lactose-malabsorbers and 10 lactose-absorbers chosen from 36 Guatemalan adults screened for their capacity to digest and absorb completely the lactose in this volume of milk. A six-hour hydrogen breath test was used as the index of carbohydrate absorption. Minimal breath H2 was excreted by lactose-absorbers with either the intact milk alone, the intact milk with solid foods, or lactose-prehydrolyzed milk with solids. In lactose-malabsorbers, however, the 6-h excretion of H2 with intact milk plus solid food was intermediary between milk alone and prehydrolyzed milk with solids. A relative net reduction of 47% in lactose malabsorption was produced by adding food, and the peak-rise in breath H2 was delayed by 2 hours. A physiological consequence of taking solid foods along with milk is a slower rate of colonic fermentation, and this may be the basis for reducing gastro-intestinal symptoms in lactose-intolerant malabsorbers.
D000328:Adult; D000818:Animals; D001944:Breath Tests; D003106:Colon / Q000378:metabolism*; D005260:Female; D005285:Fermentation; D005502:Food; D006801:Humans; D006859:Hydrogen / Q000378:metabolism; D006868:Hydrolysis; D007785:Lactose / Q000378:metabolism*; D007787:Lactose Intolerance / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D008892:Milk / Q000378:metabolism*
D006859:Hydrogen; D007785:Lactose