Rhabdomyolysis and myoglobinuria as manifestations of child abuse.
Rhabdomyolysis should be suspected in cases of physical child abuse in which there is extensive soft tissue injury. It is easily investigated using the urinalysis and serum CPK levels. Renal failure is the most common complication and manifests itself as acute tubular necrosis, sometimes accompanied by the following specific laboratory abnormalities: elevated creatinine-to-BUN ratio, hyperkalemia, and myoglobinuria. Treatment is aimed at the preservation of renal function and the prevention of complications caused by electrolyte abnormalities. A full recovery can be expected for adults with this disorder, but information about the pediatric population is sparse. Our series suggests rapid improvement with appropriate therapy.
D058186:Acute Kidney Injury / Q000209:etiology; D002648:Child; D002649:Child Abuse; D002675:Child, Preschool; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D006801:Humans; D006947:Hyperkalemia / Q000209:etiology / Q000628:therapy; D008297:Male; D009212:Myoglobinuria / Q000175:diagnosis / Q000209:etiology*; D011188:Potassium / Q000097:blood; D012206:Rhabdomyolysis / Q000209:etiology* / Q000628:therapy
D003402:Creatine Kinase; D011188:Potassium