Phospholipid composition of guinea pig lung lavage.
Phospholipids from guinea pig lung lavage were analyzed. The total lavage phospholipid content was 2.65 + 0.67 mg per gram of lung, which accounted for 85% of the total lipids in lung wash. Phosphatidylcholine (PC) accounted for over 60% of the total phospholipids. The other phospholipid fractions, in order of predominance, were phosphatidylinositol (PI), phosphatidylserine (PS), sphingomyelin (SPH), phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and lysophosphatidyl-choline (LPC). Disaturated phosphatidylcholine (DSPC) comprised 80% of the total PC, and it contained mostly palmitic acid. The DSPC content of the lung lavage fluid per square meter of alveolar surface area was 5.76 +/- 0.42 mg.
D000818:Animals; D005227:Fatty Acids / Q000032:analysis; D006168:Guinea Pigs; D008168:Lung / Q000032:analysis*; D008297:Male; D010713:Phosphatidylcholines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis*; D011663:Pulmonary Surfactants / Q000032:analysis*; D007507:Therapeutic Irrigation
D005227:Fatty Acids; D010713:Phosphatidylcholines; D010743:Phospholipids; D011663:Pulmonary Surfactants