Isolation and characterization of the apolipoprotein genes.
These types of studies lay the foundation for understanding the human apolipoproteins at the genetic level. In addition, through a few specific examples, we have already shown evidence at the DNA level that lesions in apolipoprotein genes can play a role in human atherosclerosis. This work is in its infancy but, in the future, we hope it will have a major impact on our ability to understand genetic susceptibility to atherosclerosis in the general population.
D000595:Amino Acid Sequence; D001053:Apolipoproteins / Q000235:genetics*; D001054:Apolipoproteins A / Q000235:genetics; D001057:Apolipoproteins E / Q000235:genetics; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D005796:Genes; D006801:Humans; D011110:Polymorphism, Genetic
D001053:Apolipoproteins; D001054:Apolipoproteins A; D001057:Apolipoproteins E; D004247:DNA