Reduced number of brain cells in so-called neural overgrowth.
Patten described as neural overgrowth a folding of brain tissue into the ventricles in abnormal human embryos. Intubation of chick embryo brains release cerebrospinal fluid pressure resulting in a similar folding. These folded brains have 2.5 times less tissue volume than control embryos of identical stage. This study shows, with total DNA measurements, that brain cell number is 50% less in folded brains (intubated embryos) as compared to control brain of identical staged embryos.
D000818:Animals; D001921:Brain / Q000002:abnormalities / Q000166:cytology / Q000196:embryology*; D001923:Brain Chemistry; D002452:Cell Count; D002453:Cell Cycle; D002642:Chick Embryo / Q000166:cytology*; D004247:DNA / Q000032:analysis
D004247:DNA