Cytological study and chemotactic activity in middle ear effusion.
A cellular analysis of 330 middle ear effusions (MEEs) from children with otitis media with effusion (OME) was performed with the use of cytocentrifuge prepared smears and the results were compared with their clinical data. Chemotactic activity in MEE was also determined with the use of agarose assay and compared with their cytological results. In the acute group the cellular pattern of MEE was mainly the neutrophil dominant type which was observed in 60% of this group. In the chronic group the percentage of this type of MEE decreased but was still present in 25% of them. High chemotactic activity was frequently observed especially in neutrophil dominant type MEE.
D000293:Adolescent; D002634:Chemotaxis, Leukocyte; D002648:Child; D002675:Child, Preschool; D006801:Humans; D009504:Neutrophils / Q000276:immunology; D010034:Otitis Media with Effusion / Q000276:immunology* / Q000473:pathology