Ossifying fibroma: a clinicopathologic study of sixty-four cases.
Sixty-four cases of neoplastic benign fibro-osseous lesions are presented, with clinical and radiographic follow-up in 23 instances. A marked predilection for female patients was observed, with the majority or cases arising in the molar-premolar region of the mandible. Radiographically, these neoplasms are well demarcated and may be radiolucent, radiolucent with central opacification (target appearance), or multilocular radiolucent. A benign fibro-osseous histopathologic pattern is observed with osseous, cemental, and/or ovoid-curvoid calcified deposits. This feature, along with confinement to tooth-bearing regions, supports a periodontal ligament origin. It appears that the distinction between cementifying and ossifying variants is academic, as no behavioral differences exist. The recurrence rate following curettage was found to be 28%.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005350:Fibroma / Q000000981:diagnostic imaging / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008441:Maxillary Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D009808:Odontogenic Tumors / Q000000981:diagnostic imaging / Q000473:pathology*; D010016:Osteoma / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography