[Thymus-hypophysis-thyroid interrelation in rats after administration of a heterologous extract of thymus gland].
The Authors have investigated the effects of a thymus chromatographic fraction on TSH, T3, T4 serum values in thyroidectomized and normal controls rats before and after thymus treatment. The decrease in TSH values of thyroidectomized rats points out a possible inhibitory effect which the thymus extract may have at either the level of the adenohypophysis or hypothalamus. Moreover the TSH values in the euthyroid rats after thymus treatment showed a slight decrease, this changes are much more evident in the thyroidectomized rats after thymus treatment. In fact the plasma TSH of thyroidectomized rats drops from 97.5 +/- 4 microU/ml before thymus treatment, to 76.25 +/- 10 microU/ml after thymus treatment.
D000818:Animals; D008297:Male; D010902:Pituitary Gland / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013949:Thymus Extracts / Q000494:pharmacology*; D013950:Thymus Gland / Q000502:physiology*; D013961:Thyroid Gland / Q000502:physiology*; D013965:Thyroidectomy; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D013949:Thymus Extracts; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine
Interrelation thymus-hypophyse-thyroïde chez les rats après administration d'un extrait hétérologue de thymus.