Synthesis and biological activity of (7S)-O-epoxyalkyl derivatives of daunomycinone.
Synthesis and antibacterial activity of a number of 7-O-epoxyalkyl derivatives of daunomycinone prepared from 7-O-alkenyl derivatives of daunomycinone are described along with their inhibitory effect on leukemia P 388 cells.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D007941:Leukemia P388 / Q000378:metabolism; D009279:Naphthacenes / Q000138:chemical synthesis* / Q000494:pharmacology
D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes; C019318:daunomycinone