Anatomical studies of cholecystokinin in neurons and pathways involved in neuroendocrine regulation.
A CCK-like substance has been identified in two distinct neuronal systems of the PVN which are both involved in neuroendocrine regulation. The CCK parvicellular neurons are potentially involved in the regulation of adenohypophyseal hormone secretion through projections to the external zone of the median eminence. CCK immunoreactivity was also identified in the magnocellular-neurohypophyseal system, exclusively in oxytocinergic neurons. Thus, CCK might participate in the modulation of oxytocin secretion.
D000818:Animals; D002766:Cholecystokinin / Q000032:analysis* / Q000502:physiology; D008473:Median Eminence / Q000032:analysis; D009474:Neurons / Q000032:analysis*; D009490:Neurosecretory Systems / Q000502:physiology*; D010286:Paraventricular Hypothalamic Nucleus / Q000032:analysis*; D010902:Pituitary Gland / Q000032:analysis; D051381:Rats
D002766:Cholecystokinin