The movement of radioactive molecules across dentine in vivo in the dog.
Using a technique for measuring the movement of circulating molecules across the odontoblast-dentinal complex, the movement of water and alpha-aminoisobutyric acid through dentine and into a flow cell prepared on the tooth is described. The movement of water depended on dentine thickness, and varied from 0.40 microliter/min per cm2 in a flow cell overlying an average thickness of 0.74 mm of dentine, to 1.23 microliter/min per cm2 in a flow cell with a dentinal floor of 0.40 mm average thickness. The data suggest that alpha-aminoisobutyric-acid concentrations were lower in dentinal fluid than in blood plasma.
D000621:Aminoisobutyric Acids / Q000378:metabolism*; D000818:Animals; D001834:Body Water / Q000378:metabolism*; D003804:Dentin / Q000378:metabolism*; D003806:Dentin Permeability; D004285:Dogs; D005260:Female; D008297:Male; D014316:Tritium
D000621:Aminoisobutyric Acids; D014316:Tritium; C100049:2-aminoisobutyric acid