[Specific chromosome aberrations in 3 patients with Burkitt-like leukemia (Fab: L3)].
Karyotype analysis using the Tri-staining-technique (Chromomycin A3/Distamycin A/DAPI) and subsequent DAPI/AMD staining (Schweizer, 1981) was performed on the bone marrow and peripheral blood of three patients with "Burkitt-like" acute lymphatic leukaemia (FAB: L3). In two patients we found the specific translocation t(8;22). One patient displayed in addition a structural abnormality of chromosome 9, visualized with C-banding using the DA/DAPI stain, and in two patients we found specific abnormalities of chromosome 1. Several patterns of the abnormal chromosome 1 revealed an intercalated DA/DAPI positive C-band in the elongated long arm.
D000293:Adolescent; D000328:Adult; D002051:Burkitt Lymphoma / Q000235:genetics*; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002872:Chromosome Deletion; D006801:Humans; D007231:Infant, Newborn; D007945:Leukemia, Lymphoid / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D014178:Translocation, Genetic
Spezifische Chromosomenaberrationen bei 3 Patienten mit "Burkitt-ähnlicher" Leukämie (FAB: L3).