Changes of subgingival total colony forming units and black pigmented bacteroides after a single irrigation of periodontal pockets with 1.64% SnF2.
Periodontal pockets of 11 subjects were irrigated once with either 1.64% SnF2 or saline applied by syringe. Changes on the total anaerobic colony forming units (CFU) and black pigmented bacteroides (BPBs) of the irrigated pockets were assessed for 31 days. The results showed little change of the CFUs by either single application of SnF2 or saline. However, SnF2 irrigation produced a decrease in the BPBs for 1 week with the greatest effect (1/2 log reduction) being seen at 3 days after the irrigation. Some subjects had more impressive reductions in BPBs, yet four of the 11 subjects showed no reductions in BPBs in those sites irrigated with SnF2. Further studies with frequent irrigation intervals are necessary to evaluate the potential usefulness of SnF2 for subgingival irrigation.
D000328:Adult; D001419:Bacteria / Q000302:isolation & purification*; D018407:Bacterial Physiological Phenomena; D001439:Bacteroides / Q000302:isolation & purification* / Q000502:physiology; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010514:Periodontal Pocket / Q000188:drug therapy* / Q000382:microbiology; D010518:Periodontitis / Q000188:drug therapy* / Q000382:microbiology; D007507:Therapeutic Irrigation; D013997:Time Factors; D014002:Tin Fluorides / Q000627:therapeutic use*
D014002:Tin Fluorides; D005459:Fluorides