Postirradiation cerebellar glioma. Case report.
A 13-year-old girl developed an anaplastic astrocytoma of the cerebellum 7 years after irradiation of the central nervous system and prophylactic chemotherapy for acute lymphocytic leukemia. The fact that the astrocytoma was anaplastic and infiltrative was unusual for astroglial tumors at this site. It is proposed that this is a radiation-induced glioma.
D000293:Adolescent; D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000532:radiotherapy; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D011878:Radiotherapy / Q000009:adverse effects; D014057:Tomography, X-Ray Computed