Comparative hematological data from animals implanted with a total artificial heart containing different valves.
A review of animals receiving a TAH with 4 mechanical valves suggests that the least damage to the blood cell components is associated with the BS valve when compared with the MH valve at similar heart rates. Clinical anemia in varying stages was observed in most animals in this study. However, most calves compensated for the increased rate of hemolysis and none required blood transfusions. The BS valve would appear to combine minimal turbulence and mechanical crushing in a physiological setting.
D000818:Animals; D001835:Body Weight; D002417:Cattle; D006339:Heart Rate; D006350:Heart Valve Prosthesis; D006354:Heart, Artificial / Q000009:adverse effects; D006400:Hematocrit; D006461:Hemolysis; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D012189:Retrospective Studies; D012756:Sheep
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase