A pilot study of the clinical problem of regionally anesthetizing the pulp of an acutely inflamed mandibular molar.
The diplomates of the American Association of Endodontists were surveyed regarding difficulties in regionally anesthetizing acutely painful mandibular molar teeth. Frequently patients developed evidence of adequate regional block anesthesia but experienced pain when the dentist attempted access. A pilot projection was undertaken to determine if a scientific basis existed for this problem. With the animal under general anesthesia, the mandibular nerve of a cat was isolated and then regionally blocked. A stimulating electrode was implanted in a cuspid tooth and a receiving electrode in the cortex of the brain. When a state of inflammation was created in the tooth in the presence of a regional block, there was an increasing cortical response to this stimulation. It was concluded that the pilot project offered a realistic technique for the study of this clinical entity.
D000208:Acute Disease; D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D002415:Cats; D003782:Dental Pulp / Q000503:physiopathology*; D004558:Electric Stimulation; D004567:Electrodes, Implanted; D005071:Evoked Potentials; D005625:Frontal Lobe / Q000502:physiology; D006632:Histamine / Q000494:pharmacology; D008334:Mandible; D008963:Molar / Q000503:physiopathology*; D010865:Pilot Projects; D011671:Pulpitis / Q000503:physiopathology; D014098:Toothache / Q000503:physiopathology*
D000779:Anesthetics, Local; D006632:Histamine