Cytodiagnosis of bone tumors by fine needle aspiration.
A retrospective study was undertaken of bone lesions examined by preoperative fine needle aspiration (FNA) cytology in our hospital during the ten-year period from 1970 to 1979. The 430 cytologically examined lesions were classified into three groups: inflammatory lesions, tumorlike lesions and tumors. A total of 54 patients had undergone surgery, with most of the lesions in those cases proven to be tumors or tumorlike by histologic study. Correlation between the histologic and FNA cytologic findings showed complete compatibility in 76% of the cases, partial compatibility in 13% and incompatibility in 11%. It is concluded that FNA biopsy is appropriate for identifying bone tumors and tumorlike lesions if sufficient numbers of tumor cells are obtained for morphologic examination. Although aspiration cytodiagnosis can be of considerable value in the recognition of certain bone lesions, it cannot replace formal tissue biopsy in the diagnosis of primary bone neoplasms. The morphology of several common bone tumors is described in detail and their differential diagnosis is discussed.
D001707:Biopsy, Needle; D001859:Bone Neoplasms / Q000473:pathology*; D002812:Chondroma / Q000473:pathology; D002813:Chondrosarcoma / Q000473:pathology; D002817:Chordoma / Q000473:pathology; D005354:Fibrosarcoma / Q000473:pathology; D005870:Giant Cell Tumors / Q000473:pathology; D006801:Humans; D012516:Osteosarcoma / Q000473:pathology; D012189:Retrospective Studies; D012512:Sarcoma, Ewing / Q000473:pathology