[Fibroscopy in assessing the effectiveness of radiation therapy in cancer of the upper respiratory tracts and in lymphosarcoma of the tonsillar ring].
Proceeding from 2626 fibroscopic examinations of the upper respiratory tract during radiotherapy of 492 cancer patients, the most appropriate time of control endoscopic examinations have been defined, endoscopic criteria for the evaluation of the efficacy of therapy of primary tumors of different parts of the upper respiratory tract have been determined. The evaluation of the efficacy of therapy by the common otorhinolaryngological method was compared with that of the fibroscopic method of examination. The efficacy of radiotherapy by changing endoscopic pictures is most vividly expressed in laryngeal cancer after delivering the dose of 30-40 Gy (49-66 units of TDF), in laryngeal and nasopharyngeal cancer 50 Gy (82 units of TDF) and in lymphosarcoma of the throat ring 20 Gy (33 units of TDF). In the use of the speculum and fibroscopic methods difficulties in the organ inspection and differentiation of changes were noted in 31.7 and 16.1% of the cases including 64.3 and 11.9% in laryngopharyngeal cancer and 80.9 and 1.8% in nasopharyngeal cancer. Tumor regression in concomitant involvement of the tonsils by lymphosarcoma develops not uniformly. A positive time course is first of all noted in lymphadenoid masses: in the palatine and lingual tonsils and then in the pharyngeal, tubal and laryngeal tonsils. Complete tumor regression after irradiation at a dose of 20 Gy (33 units of TDF) is noted in 50% of lymphosarcoma patients. In 13.2% of cases doses of 50 Gy (82 units of TDF) and 60 Gy (99 units of TDF) are required for complete regression of lymphosarcoma of the throat ring.
D005069:Evaluation Studies as Topic; D005336:Fiber Optic Technology; D006801:Humans; D007828:Laryngoscopy; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000532:radiotherapy; D009303:Nasopharyngeal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy; D010610:Pharyngeal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy; D011879:Radiotherapy Dosage; D012142:Respiratory Tract Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy; D013997:Time Factors; D014067:Tonsillar Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy
Fibroskopiia v otsenke éffektivnosti luchevoĭ terapii raka verkhnikhdykhatel'nykh puteĭ i limfosarkomy glotochnogo kol'tsa.