Hypervariable 'minisatellite' regions in human DNA.
The human genome contains many dispersed tandem-repetitive 'minisatellite' regions detected via a shared 10-15-base pair 'core' sequence similar to the generalized recombination signal (chi) of Escherichia coli. Many minisatellites are highly polymorphic due to allelic variation in repeat copy number in the minisatellite. A probe based on a tandem-repeat of the core sequence can detect many highly variable loci simultaneously and can provide an individual-specific DNA 'fingerprint' of general use in human genetic analysis.
D000483:Alleles; D001483:Base Sequence; D004276:DNA, Satellite / Q000235:genetics*; D005818:Genetic Engineering; D014644:Genetic Variation; D006579:Heterozygote; D006801:Humans; D009154:Mutation; D009693:Nucleic Acid Hybridization; D010375:Pedigree; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid
D004276:DNA, Satellite