Uterine leiomyosarcoma with myxoid stroma.
Myxoid leiomyosarcomas present a diagnostic problem. They are said to have low mitotic counts and are considered to be exceptions to the general rule that uterine smooth-muscle tumors with a mitotic rate of less than five per ten high-power fields rarely recur. We present two cases of myxoid leiomyosarcoma, both of which show high mitotic counts. In addition, one of the cases presented initially as a typical leiomyosarcoma, but contained abundant myxoid stroma in the metastases. The role of the myxoid stroma in influencing prognosis in leiomyosarcomas is, as yet, uncertain.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology*; D008940:Mitotic Index; D011379:Prognosis; D014594:Uterine Neoplasms / Q000473:pathology*