Abnormal splenic uptake of gallium-67 citrate in a case of infectious mononucleosis.
A case of fever of undetermined origin (FUO) demonstrated abnormal intense concentration of Ga-67 citrate in the spleen. Initial workup demonstrated two negative mono spot tests for infectious mononucleosis (IM) but, on hospital day 2, a repeat mono test was positive. The diagnosis was subsequently confirmed by rising heterophilic antibody titers. Six weeks after hospital discharge, repeat Ga-67 citrate imaging demonstrated absence of abnormal splenic activity. To our knowledge, this phenomenon has not been previously described in IM. In the appropriate clinical setting, intense splenic uptake of Ga-67 should alert the clinician to include the possibility of IM in the differential diagnosis.
D000328:Adult; D003937:Diagnosis, Differential; D005335:Fever of Unknown Origin / Q000209:etiology; D005710:Gallium Radioisotopes; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D011877:Radionuclide Imaging; D013154:Spleen / Q000000981:diagnostic imaging*
D005710:Gallium Radioisotopes