Inherited craniofacial fibrous dysplasia.
Craniofacial fibrous dysplasia occurring in a mother and two of her three daughters is reported. In all three patients, the condition was characterized by extensive bilateral and bimaxillary involvement. All patients exhibited radiographic evidence of abnormal maxillary and mandibular bone and tooth displacement. Morphologic examination of deciduous teeth from the daughters showed replacement of normal pulp tissue by fibro-osseous lesion. Because of the familial occurrence of the cases, it is proposed that they comprise an example of inherited craniofacial fibrous dysplasia.
D000328:Adult; D002648:Child; D005146:Facial Asymmetry / Q000235:genetics* / Q000473:pathology; D005147:Facial Bones / Q000473:pathology; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008336:Mandibular Diseases / Q000473:pathology; D008439:Maxillary Diseases / Q000473:pathology; D014076:Tooth Diseases / Q000473:pathology