Age-dependent decreases in human submandibular gland flow rates as measured under resting and post-stimulation conditions.
Submandibular saliva samples were obtained with a new collection device, under resting and post-stimulation conditions, from 28 healthy individuals between 70 and 91 years of age, and from 30 healthy individuals between 18 and 39 years of age. The salivary flow rates were significantly decreased in the aged group compared with the control group. The mean resting and post-stimulation flow rates for the aged group averaged 22% and 39%, respectively, of control values.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D005260:Female; D006801:Humans; D008297:Male; D012636:Secretory Rate; D013048:Specimen Handling / Q000295:instrumentation / Q000379:methods; D013268:Stimulation, Chemical; D013363:Submandibular Gland / Q000378:metabolism* / Q000502:physiology