Immunologic factors in thyroid disease.
The role of immunologic reactions against orbital-specific and orbital-thyroid antigens in the pathogenesis of autoimmune thyroid disorders and Graves' ophthalmopathy is discussed. Possible mechanisms for the association of ophthalmopathy and autoimmune thyroid disorders is discussed in relation to the role of autoantibodies against eye muscle antigens.
D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D001324:Autoantigens / Q000032:analysis / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D005128:Eye Diseases / Q000276:immunology; D005260:Female; D006111:Graves Disease / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D006980:Hyperthyroidism / Q000276:immunology; D007037:Hypothyroidism / Q000276:immunology; D007231:Infant, Newborn; D009915:Orbit / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology; D013954:Thyroglobulin / Q000276:immunology; D013959:Thyroid Diseases / Q000276:immunology*; D013966:Thyroiditis / Q000276:immunology; D013972:Thyrotropin / Q000276:immunology
D001323:Autoantibodies; D001324:Autoantigens; D006680:HLA Antigens; D013972:Thyrotropin; D013954:Thyroglobulin