Evidence of a preferential inactivation of the paternally derived X chromosome in a 46,XX true hermaphrodite.
The pattern of inheritance of several X polymorphic markers is studied in the pedigree of a 46,XX true hermaphrodite. The results of the Xga, 12E7, and G6PD segregation analysis favour the hypothesis of a preferential inactivation of the paternally derived X chromosome.
D001789:Blood Group Antigens / Q000235:genetics; D012734:Disorders of Sex Development / Q000235:genetics*; D004303:Dosage Compensation, Genetic; D005260:Female; D005819:Genetic Markers; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics; D006182:H-Y Antigen / Q000235:genetics; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D010375:Pedigree; D011110:Polymorphism, Genetic
D001789:Blood Group Antigens; D005819:Genetic Markers; D006182:H-Y Antigen; D006680:HLA Antigens; D005954:Glucosephosphate Dehydrogenase