Thyroid uptake and imaging with iodine-123 at 4-5 hours: replacement of the 24-hour iodine-131 standard.
A study was carried out to determine the suitability of utilizing a 4 to 5 hr interval from administration of iodine-123 to imaging and uptake measurement as a replacement for the 24-hr standard originally established with iodine-131. In 55 patients who underwent scintigraphy at 4 and 24 hr, there was no discrepancy between paired images. In 55 patients who had uptake measured at 4 and 24 hr and in 191 patients who had uptake measured at 5 and 24 hr, the early measurements proved equal or better discriminants of euthyroid from hyperthyroid patients. In our institutions, these findings and the logistical advantages of completing the exam in 4-5 hr led us to abandon the 24-hr study in the majority of patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D005260:Female; D006044:Goiter, Nodular / Q000000981:diagnostic imaging; D006111:Graves Disease / Q000000981:diagnostic imaging; D006801:Humans; D006980:Hyperthyroidism / Q000000981:diagnostic imaging; D007037:Hypothyroidism / Q000000981:diagnostic imaging; D007223:Infant; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013959:Thyroid Diseases / Q000000981:diagnostic imaging; D013961:Thyroid Gland / Q000000981:diagnostic imaging*; D013966:Thyroiditis / Q000000981:diagnostic imaging; D013997:Time Factors
D007457:Iodine Radioisotopes