Occurrence of an astrocytoma in a patient with Williams syndrome.
The Williams elfin facies syndrome (Williams-Beuren syndrome) is a disorder characterized by a typical facies, supravalvular aortic stenosis and mental retardation. Its coexistence with a brain tumor has, so far, never been described. Recently, we treated a patient who was previously diagnosed as having Williams syndrome for a cerebral astrocytoma. In view of the incidence of astrocytomas in children and the occurrence of Williams syndrome, we want to report this coincidence.
D001024:Aortic Valve Stenosis / Q000151:congenital*; D001254:Astrocytoma / Q000150:complications*; D001932:Brain Neoplasms / Q000150:complications*; D002675:Child, Preschool; D005147:Facial Bones / Q000002:abnormalities*; D006801:Humans; D008607:Intellectual Disability / Q000150:complications*; D008297:Male; D013577:Syndrome