Risk factors for coronary heart disease: a case-control study.
Risk factors for myocardial infarction and sudden death have been examined in caucasians using data from a population-based register of coronary disease and an electoral roll sample of adult Aucklanders. The risk factors studied were past history of treatment for hypertension, cigarette smoking, body mass index, serum cholesterol and in men a history of vasectomy. A total of 625 myocardial infarction cases and 185 sudden death cases were compared with 1586 controls aged 35-64 years. In univariate and multivariate analyses in both sexes a history of treatment for hypertension and cigarette smoking were each associated with more than doubling of the risk for myocardial infarction and sudden death. Both men and women with a very high body mass index were at increased risk for myocardial infarction, and serum cholesterol was associated with an increased risk of myocardial infarction in men. Approximately one half of the myocardial infarction events and over half of the sudden death events occurring in this population were attributable to hypertension and smoking.
D000328:Adult; D001835:Body Weight; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000209:etiology*; D003645:Death, Sudden / Q000209:etiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D009520:New Zealand; D012044:Regression Analysis; D012306:Risk; D012907:Smoking; D014659:Vasectomy / Q000009:adverse effects; D044465:White People
D002784:Cholesterol