Effect of prolactin and bromocriptine administration on epididymal function--a biochemical study in rats.
The pattern of androgen dependent enzyme activities of epididymis was studied after the administration of prolactin and bromocriptine in albino rats. Prolactin activated the glycogenolysis and hexose mono and diphosphate pathways, which would be essential for sperm maturation. But bromocriptine inhibited these activities of epididymis. Hence role of bromocriptine in decreasing epididymal function has been suggested.
D000818:Animals; D001971:Bromocriptine / Q000494:pharmacology*; D004822:Epididymis / Q000187:drug effects*; D006003:Glycogen / Q000378:metabolism; D006600:Hexosephosphates / Q000378:metabolism; D008297:Male; D008433:Mathematics; D011388:Prolactin / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D006600:Hexosephosphates; D001971:Bromocriptine; D011388:Prolactin; D006003:Glycogen