A cautionary note on the resolution of paraquat lung damage after radiotherapy.
We have been able to model the lung damage caused by paraquat in our mice and have found a dose-related increase in lung damage after PQ. Unfortunately we have not found a radiation dose or optimum time for irradiation which shows a reduction of the PQ lung damage.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D008168:Lung / Q000187:drug effects / Q000528:radiation effects*; D051379:Mice; D010269:Paraquat / Q000633:toxicity*; D011879:Radiotherapy Dosage; D013997:Time Factors
D010269:Paraquat