Effect of methylprednisolone on complications after removal of impacted mandibular third molars.
Bilateral impacted mandibular third molars were surgically removed in 20 healthy patients. The effects of methylprednisolone on postoperative healing was investigated in a double-blind, cross-over study. Some decrease in postoperative discomfort (swelling and trismus) was noted in the methylprednisolone group. No statistically significant difference was noted, however in comparison with a placebo group.
D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible; D008775:Methylprednisolone / Q000494:pharmacology / Q000627:therapeutic use*; D008964:Molar, Third / Q000601:surgery*; D010149:Postoperative Pain / Q000517:prevention & control; D011183:Postoperative Complications / Q000517:prevention & control*; D011897:Random Allocation; D014081:Tooth Extraction / Q000009:adverse effects; D014095:Tooth, Impacted / Q000601:surgery*; D014313:Trismus / Q000517:prevention & control; D014945:Wound Healing / Q000187:drug effects
D008775:Methylprednisolone