A model for red cell O2 uptake.
A computer model for red cell O2 uptake in the pulmonary capillary circulation is described. New features include the effect of hematocrit on blood viscosity and cardiac output and the precise modeling of the hemoglobin-O2 saturation curve as it varies with pH, the 2,3-DPG/Hb molar ratio, and PCO2 during oxygenation. The model is useful in the integration of many interacting physiologic variables that regulate O2 transport.
D000328:Adult; D000368:Aged; D001809:Blood Viscosity; D002196:Capillaries; D002302:Cardiac Output; D004912:Erythrocytes / Q000378:metabolism*; D006400:Hematocrit; D006801:Humans; D008168:Lung / Q000098:blood supply; D008875:Middle Aged; D008954:Models, Biological; D010100:Oxygen / Q000097:blood*; D012984:Software
D010100:Oxygen