Co-release of neuropeptide Y and catecholamines during physical exercise in man.
Venous plasma levels of neuropeptide Y-like immunoreactivity (with chromatographic properties of synthetic neuropeptide Y) increased in parallel with catecholamines, heart rate and blood pressure during graded physical exercise in man. The plasma levels of neuropeptide Y correlated better with the levels of noradrenaline than adrenaline, suggesting release of a neural origin. Taken together with previous results, this suggests that neuropeptide Y is released together with noradrenaline upon sympathetic activation during physiological conditions in man. Determinations of plasma neuropeptide Y may therefore be valuable in the assessment of sympathetic nerve activity.
D000328:Adult; D002395:Catecholamines / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000097:blood / Q000378:metabolism*; D009478:Neuropeptide Y; D005082:Physical Exertion; D013564:Sympathetic Nervous System / Q000502:physiology
D002395:Catecholamines; D009419:Nerve Tissue Proteins; D009478:Neuropeptide Y