Effects of an anabolic steroid on reproduction in female rats.
Mature female rats given food and water ad libitum and maintained under a lighting schedule of 12h light/12h dark were treated with boldenone undecylenate. Neither dosage nor duration of treatment had a significant effect on weight gain when compared to controls. All treated females were characterized by the absence of cyclic ovarian activity that continued for several weeks following termination of treatment. Long term reproductive performance was altered by a significant reduction in both conception rate and neonatal survival. Behavioral patterns were modified for several months following steroid withdrawal.
D000374:Aggression / Q000187:drug effects; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002190:Cannibalism; D005260:Female; D005298:Fertility / Q000187:drug effects; D008098:Litter Size / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D010053:Ovary / Q000187:drug effects / Q000473:pathology; D011247:Pregnancy; D051381:Rats; D012098:Reproduction / Q000187:drug effects*; D013739:Testosterone / Q000031:analogs & derivatives* / Q000494:pharmacology
D013739:Testosterone; C001371:boldenone undecylenate