[Tumor-associated markers as organ-specific antigens of human seminal plasma. I. Immunologic studies].
We could demonstrate that some constituents of the human seminal plasma must be regarded as organ-specific substances; these are known as characteristic tumor markers in connection with other subjects. Accordingly, the occurrence of the tumor markers Ca 19-9tm, CEA and Ca 12-5tm in samples of normal human seminal plasma shows that these materials must be defined in this case as organ-characteristic markers. We report on different quantitative distribution of these markers and give evidence that the Ca 19-9 antigen only occurs in persons positive with respect to Lewis' blood group.
D000951:Antigens, Neoplasm / Q000032:analysis*; D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D006801:Humans; D007983:Lewis Blood Group Antigens / Q000276:immunology*; D008297:Male; D019158:N-Acetylneuraminic Acid; D009928:Organ Specificity; D011863:Radioimmunoassay; D012661:Semen / Q000032:analysis / Q000201:enzymology / Q000276:immunology*; D012794:Sialic Acids / Q000032:analysis; D012799:Sialyltransferases / Q000032:analysis; D014659:Vasectomy
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D002272:Carcinoembryonic Antigen; D007983:Lewis Blood Group Antigens; D012794:Sialic Acids; D012799:Sialyltransferases; D019158:N-Acetylneuraminic Acid
Tumor-assoziierte Marker als organ-charakteristische Antigen des menschlichen Seminalplasmas. I. Immunologische Studien.