Properties of the zona pellucida of cytochalasin B-induced triploid mouse eggs.
The hardening of the zona pellucida as a result of the cortical reaction was estimated in triploid oocytes produced with cytochalasin B by two different procedures. Triploid oocytes resulting from fertilization in the presence of cytochalasin B did not reveal hardening of the zona pellucida unlike triploids obtained by inhibiting in-vitro extrusion of the second polar body in oocytes fertilized in vivo.
D000818:Animals; D003571:Cytochalasin B / Q000494:pharmacology*; D005260:Female; D005307:Fertilization in Vitro / Q000187:drug effects; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010063:Ovum / Q000502:physiology*; D011123:Polyploidy; D013084:Sperm-Ovum Interactions / Q000187:drug effects; D013997:Time Factors; D015044:Zona Pellucida / Q000502:physiology*
D003571:Cytochalasin B