Interradicular dentin dysplasia associated with amelogenesis imperfecta.
Very few reports are available on the occurrence of dysplasia of both enamel and dentin. This report concerns a rare association of amelogenesis imperfecta with a dysplasia of dentin in the interradicular area in sisters of Japanese descent who have no other morphologic anomalies. Retarded tooth eruption was also a clinical feature in both sisters. Histologic examination of several teeth revealed that the anomalous interradicular dentin consisted of a mass of small, onion-like calcified bodies. The absence of any dental abnormalities in both parents, who are related as first cousins, supports the concept of autosomal recessive inheritance for this trait.
D000293:Adolescent; D000567:Amelogenesis Imperfecta / Q000235:genetics* / Q000473:pathology; D002648:Child; D003743:Dental Enamel / Q000473:pathology; D003805:Dentin Dysplasia / Q000235:genetics* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008963:Molar / Q000002:abnormalities / Q000473:pathology