[Biological studies of Gore-Tex vascular prostheses].
In 1981 we received the Gore-Tex PTFE vascular prostheses, 12 mm in diameter, in order to test their value. Experimental studies were carried out on 6 piglets, in which 5 cm long sections of the prostheses under study were grafted into surgical defects of the thoracic aorta. The dissections were made 1, 3, 6 months after grafting, each time detailed pathomorphological studies were carried out. The results show that PTFE prostheses, grafted into a piglet thoracic aorta was surrounded by fibrinous connective tissue. The tissue on the outside of the prostheses differs in histological structure from that inside. After 6 months it was found that the prosthesis has inside a thin layer of fibrinous connective tissue, connected to the prostheses wall; the layer did not constrict the internal diameter. The Gore-Tex prostheses fulfill biological requirements on vascular prostheses after their grafting into operational defects of the aorta.
D000818:Animals; D001013:Aorta, Thoracic / Q000166:cytology / Q000601:surgery*; D001672:Biocompatible Materials; D001807:Blood Vessel Prosthesis; D003239:Connective Tissue Cells; D004548:Elasticity; D005069:Evaluation Studies as Topic; D005500:Follow-Up Studies; D011138:Polytetrafluoroethylene; D013552:Swine; D013718:Tensile Strength; D013997:Time Factors; D014481:United States
D001672:Biocompatible Materials; D011138:Polytetrafluoroethylene
Badania biologiczne protez naczyniowych Gore-Tex.