The Coulter Counter leukocyte differential.
The leukocyte differential counting capability of the Coulter Counter model S-PLUS IV was evaluated for precision, accuracy, and clinical sensitivity. The evaluation used procedures described in the NCCLS tentative standard (H20-T) when these were appropriate for this technology. Within its inherent constraints, the system was found to be more reproducible than the stained-film reference method and at least as accurate. Clinical sensitivity was equivalent to that of a four-slide, microscope differential count. Reference ranges for the cell classes identified by the instrument were similar to those given by the stained-film method.
D001699:Biometry; D003951:Diagnostic Errors; D004804:Eosinophils; D005069:Evaluation Studies as Topic; D006801:Humans; D007958:Leukocyte Count / Q000295:instrumentation* / Q000379:methods; D008214:Lymphocytes; D011786:Quality Control; D012016:Reference Values