Histopathology of the initial lesion of the root surface: an in vitro study.
An acidified gel system was used to produce artificial caries lesions in root surfaces. Radiopaque surface layers were found with 47% of the lesions. Demineralized bodies of the lesion and mineralized zones of banding were seen in all lesions when examined by microradiography. Cementum and dentin seemed to respond to the acid attack in a similar manner. Although artificial root lesions did not simulate natural root caries entirely, the acidified gel system resulted in a reproducible method that might give insight into initial lesion formation on root surfaces. This technique may be used for studying the physico-chemical process involved in the demineralization of root surfaces and for testing the effects of various agents in the prevention of root caries.
D000368:Aged; D003731:Dental Caries / Q000000981:diagnostic imaging / Q000473:pathology*; D003739:Dental Cementum / Q000000981:diagnostic imaging / Q000473:pathology; D003743:Dental Enamel / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008852:Microradiography; D008859:Microscopy, Polarization; D008875:Middle Aged; D014092:Tooth Root / Q000000981:diagnostic imaging / Q000473:pathology*