Orbital rhabdomyosarcoma: improved survival with combined pulsed chemotherapy and irradiation.
Three cases of embryonal orbital rhabdomyosarcoma are presented in which two cases had intracranial extension. All three are alive and well on follow-up several years after completing a 12-month course of combined pulsed chemotherapy and irradiation. The improved prognosis even in parameningeal involvement is emphasised.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy; D011379:Prognosis; D012208:Rhabdomyosarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide