Topical use of PVP-I (Betadine) preparations in patients with spinal cord injury.
Povidone-iodine (PVP-I) has a wide range of activity against bacteria. The author's clinical experience has indicated that it can be used successfully as a topical agent in the treatment of decubital ulcer in patients with spinal cord injury. To date, 110 patients have been treated with Betadine solution and ointment, topically applied at daily intervals. Of these, 70 patients had decubitus ulcers involving the sacral and trochanter region; 20 were chronic ulcers which cleared up well. Another 20 required rotation grafting procedure. Primary healing was achieved in all patients (1-4).
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D002648:Child; D006801:Humans; D008875:Middle Aged; D011205:Povidone / Q000031:analogs & derivatives*; D011206:Povidone-Iodine / Q000627:therapeutic use*; D003668:Pressure Ulcer / Q000188:drug therapy* / Q000209:etiology; D013119:Spinal Cord Injuries / Q000150:complications*; D014946:Wound Infection / Q000188:drug therapy / Q000382:microbiology
D011206:Povidone-Iodine; D011205:Povidone