Evidence that the redox state has a role in muscular contraction and relaxation.
The present work reports that simple oxidizing agents are capable of inducing isotonic contraction of rat aorta in vitro, and that the concentration of agent required depends on its oxidizing potential. Conversely a reducing agent will reverse a muscular contraction induced by oxidizing agents.
D000818:Animals; D001011:Aorta / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D009119:Muscle Contraction / Q000187:drug effects; D009126:Muscle Relaxation / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D010084:Oxidation-Reduction; D011196:Potassium Permanganate / Q000494:pharmacology; D051381:Rats
D011196:Potassium Permanganate