3-Mercaptopyruvate sulfurtransferase activity in guinea pig and rat tissues.
Activities of 3-mercaptopyruvate sulfurtransferase (EC 2.8.1.2) in guinea pig tissues were determined and compared with those in the corresponding rat tissues. The activities in guinea pig tissues were found to be very low. The activity in the liver was 145.9 mumol pyruvate formed per g of fresh tissue per 15 min. This was 1/50 of the activity in the rat liver. Activities in the kidney and brain were 1/100 of the corresponding rat tissues. Those in the erythrocyte and heart were negligibly low and far less than 1/1000 of these tissues in the rat. Similarities between the guinea pig and patients with beta-mercaptolactate-cysteine disulfiduria are discussed.
D000818:Animals; D001921:Brain / Q000201:enzymology; D004912:Erythrocytes / Q000201:enzymology; D006168:Guinea Pigs; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008297:Male; D009206:Myocardium / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity; D013466:Sulfurtransferases / Q000378:metabolism*; D014018:Tissue Distribution
D013466:Sulfurtransferases; C021550:3-mercaptopyruvate sulphurtransferase