Histologic changes in rat brain tissue caused by neodymium-yttrium aluminum garnet laser irradiation. II. Cerebellum.
Histologic changes after neodymium-yttrium aluminum garnet laser irradiation were evaluated in the rat cerebellum. Irradiation of 60 W (corresponds to 45.2 W/mm2) to the posterior fossa was dangerous even in adult rats, although this value was safe for the rat cerebral hemisphere as previously reported. The histologic changes caused by neodymium-yttrium aluminum garnet laser irradiation were similar to those caused by thermal energies. To the adult rat cerebellum, 45 W (35.2 W/mm2) can safely be applied. For the further use of the neodymium-yttrium aluminum garnet laser in neurosurgery, our findings should be taken into consideration.
D000818:Animals; D001921:Brain / Q000473:pathology / Q000528:radiation effects*; D002470:Cell Survival; D002531:Cerebellum / Q000473:pathology / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D007834:Lasers / Q000009:adverse effects*; D051381:Rats