[Hemodynamic effects of molsidomine in patients with cardiac insufficiency at high altitudes].
Central hemodynamic effects of 0.05 mg/kg molsidomine were examined in 60 patients with decompensated mitral disease dwelling at low and medium altitudes. M-echocardiography was used to assess hemodynamic shifts. The assessments were made during the diagnostic probing of a pulmonary artery in 23 cases. Hemodynamic efficacy of molsidomine was more pronounced up in the mountains. Rationale are given for expanding indications for peripheral vasodilators (molsidomine) in highlanders with congestive heart failure.
D000293:Adolescent; D000328:Adult; D000531:Altitude; D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008981:Molsidomine; D009200:Myocardial Contraction; D010069:Oxadiazoles / Q000627:therapeutic use*; D013558:Sydnones / Q000627:therapeutic use*
D010069:Oxadiazoles; D013558:Sydnones; D008981:Molsidomine
Gemodinamicheskie éffekty molsidomina u bol'nykh s serdechnoĭ nedostatochnost'iu v usloviiakh gornoĭ mestnosti.