A myelodysplastic syndrome preceding acute lymphoblastic leukaemia.
The bone marrow of a patient with pancytopenia showed dyserythropoiesis, dysmegakaryocytopoiesis and 13% blasts. The patient was hypertransfused and the pancytopenia resolved completely for 1 month, while the blastic infiltration in the bone marrow remained. Three months later a frank acute lymphoblastic leukaemia developed.
D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications*; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000473:pathology; D014411:Neoplastic Stem Cells / Q000473:pathology; D010198:Pancytopenia / Q000150:complications* / Q000473:pathology; D013577:Syndrome; D013997:Time Factors