Sensitivity of Salmonella and Shigella to antibiotics and chemotherapeutic agents in Sudan.
Antibacterial sensitivity tests were done for 513 salmonellae and 133 shigellae. Salmonella strains were divided into three groups: 336 Salmonella typhi, 134 salmonellae isolated from cases of gastroenteritis and 43 salmonellae isolated from non-human sources. All salmonellae and shigellae were sensitive to chloramphenicol. All salmonellae were sensitive to co-trimoxazole, while shigellae showed 18% of resistance. Salmonella resistance to ampicillin was low compared with a high resistance in shigellae. No resistance to from non-human sources. In analysing the resistance pattern in the 4-year period 1979-1982, it was found that there was a rising resistance to ampicillin and sulphonamides in salmonellae. In contrast there was no significant increase in resistance to tetracycline. Tetracycline resistance was high in cases of salmonellae isolated from gastroenteritis. A comparatively low resistance to streptomycin was detected in Salmonella isolated from non-human sources.
D000667:Ampicillin / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004405:Dysentery, Bacillary / Q000382:microbiology; D005759:Gastroenteritis / Q000382:microbiology; D006801:Humans; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D012475:Salmonella / Q000187:drug effects*; D012480:Salmonella Infections / Q000382:microbiology; D012485:Salmonella typhi / Q000187:drug effects; D012760:Shigella / Q000187:drug effects*; D013397:Sudan; D013449:Sulfonamides / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D014435:Typhoid Fever / Q000382:microbiology
D000900:Anti-Bacterial Agents; D013449:Sulfonamides; D000667:Ampicillin; D013752:Tetracycline