Provisional mapping of the gene for a cell surface marker, GA-1, in the red-necked wallaby Macropus rufogriseus.
A series of M. rufogriseus-mouse somatic cell hybrids was constructed and analysed cytologically, enzymatically and immunologically. A monoclonal antibody, GA-1, was prepared against an M. rufogriseus cell surface antigen on an M. rufogriseus-mouse somatic cell hybrid. A gene determining the expression of this antigen was provisionally assigned to the long arm of the M. rufogriseus chromosome 3. The monoclonal antibody also reacted with an M. rufus (red kangaroo)-mouse somatic cell hybrid containing only the M. rufus chromosome 5, the G-banded chromosome identical to M. rufogriseus 3q. The results also suggest synteny of the genes for the marsupial enzymes hypoxanthine phosphoribosyltransferase and phosphoglycerate kinase-A.
D000818:Animals; D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D000954:Antigens, Surface / Q000235:genetics*; D002460:Cell Line; D002478:Cells, Cultured; D002871:Chromosome Banding; D002874:Chromosome Mapping; D003429:Cross Reactions; D005796:Genes; D006822:Hybrid Cells / Q000166:cytology; D007041:Hypoxanthine Phosphoribosyltransferase / Q000172:deficiency; D007621:Karyotyping; D007614:Macropodidae / Q000235:genetics*; D008394:Marsupialia / Q000235:genetics*; D051379:Mice; D008810:Mice, Inbred C57BL
D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D000954:Antigens, Surface; D007041:Hypoxanthine Phosphoribosyltransferase