Prostaglandin inhibition and the rate of recovery after arthroscopic meniscectomy. A randomised double-blind prospective study.
In a double-blind, randomised, prospective study of 139 patients undergoing arthroscopic meniscectomy, those receiving a prostaglandin inhibitor (naproxen sodium) had significantly less pain, less synovitis and less effusion. They had significantly more rapid return of movement and of quadriceps function; their return to work and to sport also was significantly faster. It is recommended that, provided there are no contraindications, a prostaglandin inhibitor should be used after arthroscopic procedures.
D000293:Adolescent; D000328:Adult; D001182:Arthroscopy; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000502:physiology; D008297:Male; D008592:Menisci, Tibial / Q000601:surgery*; D008875:Middle Aged; D009068:Movement; D009288:Naproxen / Q000627:therapeutic use*; D011182:Postoperative Care; D011446:Prospective Studies; D011448:Prostaglandin Antagonists / Q000627:therapeutic use*; D011897:Random Allocation; D013997:Time Factors
D011448:Prostaglandin Antagonists; D009288:Naproxen