An oral disease prevention program for patients receiving radiation and chemotherapy.
Thirteen years of treating more than 2,950 patients at the National Institute of Dental Research clinic have shown that a variety of potential oral sequelae associated with cancer therapy can be prevented, reduced in severity, or palliatively alleviated when the dental team has an opportunity to participate in the patient's care. The keystone of this success is based on early referral of the patient for dental consultation, treatment before the initiation of cancer therapy, and a well-defined orientation program to inform patients and their families about the difficulties they may experience. Meticulous attention to oral microbial control, prophylactic use of fluoride gels, and palliative treatment of soft tissue lesions may significantly reduce the oral morbidity associated with radiation and cytotoxic chemotherapy. Diligent personal oral health care and frequent dental recall appointments are recommended for the remainder of the patient's life. It has been our experience that patients who are not followed closely after irradiation therapy have an increased incidence of caries as a result of noncompliance with preventive regimens. The ethical and medicolegal responsibility to fully inform the patient of these recommendations lies with both the medical and dental personnel at the facility providing the radiation-chemotherapy service. The general dentist shares the responsibility for continuity of long-term oral health care.
D000700:Analgesics / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001791:Blood Platelet Disorders / Q000150:complications; D003731:Dental Caries / Q000517:prevention & control; D005460:Fluorides, Topical / Q000627:therapeutic use; D006801:Humans; D009059:Mouth Diseases / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control*; D009369:Neoplasms / Q000097:blood / Q000188:drug therapy / Q000532:radiotherapy*; D009910:Oral Hygiene; D010353:Patient Education as Topic; D012017:Referral and Consultation; D018805:Sepsis / Q000517:prevention & control; D014987:Xerostomia / Q000209:etiology / Q000628:therapy
D000700:Analgesics; D000900:Anti-Bacterial Agents; D005460:Fluorides, Topical