Secretory carcinoma of the breast in an adult. Correlation of aspiration cytology and histology on the biopsy specimen.
Needle aspiration was performed on the excisional biopsy specimen of a breast mass in a 63-year-old woman. The cytologic features in the aspirate included solid and papillary proliferations of tumor cells with abundant intracytoplasmic vacuolization and secretion. Histologic study of the lesion showed a secretory carcinoma. Although this is a rare breast neoplasm, especially in adults, the cellular features are characteristic and may permit a specific diagnosis on needle aspirates.
D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000648:ultrastructure; D002277:Carcinoma / Q000378:metabolism* / Q000473:pathology / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008875:Middle Aged; D014617:Vacuoles / Q000648:ultrastructure