Optimal dosage regimen calculation program based on the remaining drug concentrations in plasma.
A program is presented to calculate the optimal drug doses to make the plasma drug concentration at a constant level throughout the therapy. The package requires data input of experimentally determined pharmacokinetic parameters such as As and ramdas, and provides the optimal intravenous drug doses at every minute. This program is applicable to any drug in a given individual, provided that the single-dose plasma concentration curve equation of the first dose of the therapy in this individual is known.
D001699:Biometry; D003201:Computers; D006801:Humans; D007263:Infusions, Parenteral; D008012:Lidocaine / Q000008:administration & dosage / Q000097:blood; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000097:blood; D012984:Software
D004364:Pharmaceutical Preparations; D008012:Lidocaine