Haemagglutinin transport mutants.
Two mutants (ts1 and ts651) with a temperature sensitive defect in the intracellular transport of the haemagglutinin from the rough endoplasmic reticulum to the plasma membrane have been analysed. Nucleotide sequencing of the haemagglutinin revealed with each mutant two point mutations that are located in the stem region of the molecule.
D001483:Base Sequence; D001693:Biological Transport, Active; D002462:Cell Membrane / Q000276:immunology / Q000378:metabolism; D004247:DNA / Q000235:genetics; D004721:Endoplasmic Reticulum / Q000276:immunology / Q000378:metabolism; D005814:Genes, Viral; D006389:Hemagglutinins, Viral / Q000235:genetics*; D009980:Influenza A virus / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D008968:Molecular Conformation; D009154:Mutation; D013696:Temperature
D006389:Hemagglutinins, Viral; D004247:DNA