Results of the Sherbrooke-Lac Mégantic fluoride varnish study after 20 months.
The purpose of this study was to demonstrate the effectiveness of two fluoride varnishes (Duraphat and Fluor Protector) in the prevention of dental caries in children residing in a non-fluoridated community. At baseline, 787 grade one children (6-7-yr old) were examined and randomly allocated into a control and two treatment groups. At 20 months, 703 children remained in the study. The mean baseline caries experience and the mean number of permanent teeth present at 20 months were not significantly different among the treatment and control groups. The mean DMFS increments after 20 months were 1.70, 1.73 and 2.02 for Fluor-Protector, Duraphat and control groups respectively (% reductions of 15.8 and 14.4 for Fluor-Protector and Duraphat groups). The mean dfs increments for primary molars after 20 months were 1.56, 1.62 and 1.74 for Fluor-Protector, Duraphat and control groups respectively (% reductions of 10 for Fluor-Protector and 7 for Duraphat).
D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D004338:Drug Combinations / Q000627:therapeutic use; D005460:Fluorides, Topical / Q000627:therapeutic use*; D006801:Humans; D011140:Polyurethanes / Q000627:therapeutic use*; D011792:Quebec; D011897:Random Allocation; D012821:Silanes / Q000627:therapeutic use*; D012825:Silicon / Q000627:therapeutic use*; D012969:Sodium Fluoride / Q000627:therapeutic use*
D004338:Drug Combinations; D005460:Fluorides, Topical; D011140:Polyurethanes; D012821:Silanes; C023807:sodium fluoride topical preparation; C022599:Fluor Protector; D012969:Sodium Fluoride; D012825:Silicon