Serum protein profile in normal pregnancy and in relation to parity.
Forty pregnant females of third trimester and their twenty non-pregnant controls were screened for Hb%, PCV and serum protein differentials in relation to parity. Paper electrophoresis method revealed significant rise in mean levels of serum alpha 1, alpha 2 and beta-globulins in pregnant females as compared to non-pregnant controls, which may be due to the rise in pregnancy-associated-proteins. Radial immunodiffusion method revealed rise in mean serum IgM level with increasing parity, whereas a decrease in mean serum IgG level was observed which might be due to the placental membrane-transfer and/or decreased IgG synthesis. Haematological investigations revealed decreased Hb% and PCV which may have been caused both due to increased demand of nutrients as well as by haemodilution, associated with water retention during pregnancy.
D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D004590:Electrophoresis, Paper; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D010298:Parity; D011247:Pregnancy / Q000097:blood* / Q000276:immunology; D011263:Pregnancy Trimester, Third; D012709:Serum Albumin / Q000032:analysis
D001798:Blood Proteins; D007074:Immunoglobulin G; D012709:Serum Albumin