Antihepatoxic constituents of Garcinia kola seeds.
Kolaviron, a fraction of defatted methanolic extract and biflavanones of Garcinia kola seeds significantly antagonized the lethal poisoning of mice with phalloidin. Garcinia biflavanones GB1, GB2 and kolaflavanone were isolated as the active constituents.
D000818:Animals; D005260:Female; D005419:Flavonoids / Q000494:pharmacology / Q000627:therapeutic use*; D008107:Liver Diseases / Q000517:prevention & control*; D051379:Mice; D009842:Oligopeptides / Q000037:antagonists & inhibitors*; D010590:Phalloidine / Q000037:antagonists & inhibitors*; D010946:Plants, Medicinal; D012639:Seeds
D005419:Flavonoids; D009842:Oligopeptides; D010590:Phalloidine; C045492:kolaviron