[Prognosis of surviving children with neurologic complications in the intensive phase of leukemia treatment].
32 children survived neurological complications during the treatment of ALL, AML or NHL (intracranial bleeding, convulsions, infections, severe neuropathy, severe EEG-slowing). Neurological, electroencephalographic and psychological examinations were performed 6 months to 6 years after the end of maintenance therapy. Findings were normal or borderline in about 70% of the patients. 20% presented with neurological signs, due to localised cerebral or peripheral lesions. However, these generally did not interfere to high degree with the daily living skills. The frequencies of school problems and of abnormal psychological findings were similar to these found in ALL patients without neurological complications.
D001925:Brain Damage, Chronic / Q000209:etiology*; D001932:Brain Neoplasms / Q000150:complications; D002648:Child; D004569:Electroencephalography; D005071:Evoked Potentials / Q000187:drug effects; D006801:Humans; D007859:Learning Disabilities / Q000209:etiology; D007938:Leukemia / Q000150:complications* / Q000628:therapy; D007945:Leukemia, Lymphoid / Q000150:complications; D015470:Leukemia, Myeloid, Acute / Q000150:complications; D008223:Lymphoma / Q000150:complications; D011379:Prognosis; D011596:Psychomotor Disorders / Q000209:etiology; D014750:Vincristine / Q000009:adverse effects / Q000627:therapeutic use
D014750:Vincristine
Zur Prognose überlebender Kinder mit neurologischen Komplikationen in der Intensivphase der Leukämiebehandlung.