[Prostaglandin therapy in newborn infants with a Botalli duct-dependent circulation].
21 patients are described with either the pulmonary or the systemic circulation dependent on the patency of the ductus arteriosus. Treatment with Prostaglandin type E (PGE) was instituted to improve tissue oxygenation. Special PGE 2. It is concluded that PGE can be life-saving in critically ill newborns but that complications, especially episodes of apnoea, are frequent. Little is known about the possible sequelae of long-term oral PGE 2-treatment.
D000284:Administration, Oral; D000527:Alprostadil; D001024:Aortic Valve Stenosis / Q000188:drug therapy; D015232:Dinoprostone; D004374:Ductus Arteriosus, Patent / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007263:Infusions, Parenteral; D008297:Male; D011458:Prostaglandins E / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D014188:Transposition of Great Vessels / Q000188:drug therapy
D011458:Prostaglandins E; D000527:Alprostadil; D015232:Dinoprostone
Prostaglandine-therapie bij pasgeborenen met een ductus Botalli-afhankelijke circulatie.