Skin tests with autologous cholesteryl hemisuccinate treated tumour cells in cancer patients.
Skin tests with autologous irradiated tumour cells were performed in 20 malignant melanoma, 7 breast and 6 ovarian cancer patients. In the majority of cases evident reaction was noted with cholesteryl hemisuccinate (CHS)-treated cells while the reaction with untreated cells was mostly negative. No correlation was found between this reactivity and the ability of patients to be sensitized to DNCB and to their reactivity to PPD. No correlation was found between reactivity to CHS-treated tumour cells and the stage and course of the disease.
D001943:Breast Neoplasms / Q000276:immunology; D002788:Cholesterol Esters / Q000494:pharmacology*; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed; D008545:Melanoma / Q000276:immunology; D009369:Neoplasms / Q000276:immunology*; D010051:Ovarian Neoplasms / Q000276:immunology; D012882:Skin Tests
D002788:Cholesterol Esters; C013440:cholesteryl succinate