Molecular cloning of the RAD10 gene of Saccharomyces cerevisiae.
We have cloned the RAD10 gene of Saccharomyces cerevisiae and physically mapped it to a 1.0-kb DNA fragment. Strains containing disruptions of the RAD10 gene were found to show enhanced UV sensitivity compared with the previously characterized rad10-1 or rad10-2 mutants. The UV sensitivity of the disruption mutant is comparable to the highly UV sensitive rad1-19, rad2-delta, and rad3-2 mutants.
D003001:Cloning, Molecular; D004260:DNA Repair; D004271:DNA, Fungal / Q000235:genetics / Q000528:radiation effects; D005656:Fungal Proteins / Q000235:genetics* / Q000502:physiology; D005800:Genes, Fungal; D011740:Pyrimidine Dimers / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism / Q000528:radiation effects; D014466:Ultraviolet Rays
D004271:DNA, Fungal; D005656:Fungal Proteins; D011740:Pyrimidine Dimers