title: Fibrous mass complicating epidural morphine infusion.
abstract: The benefits of continuous epidural morphine infusion using an implanted pump delivery system to control intractable cancer pain have recently been described. Most articles on this subject relate to dosage, technique, degree of pain relief, and tolerance. There are some anticipated complications of the treatment related to the surgical implantation of the system and drug toxicity. We present a complication presumably related to the epidural catheter. A fibrous reaction that developed around the catheter tip progressed into a mass. This caused a significant displacement of the spinal cord with the development of long tract symptoms. Identification of this abnormality using myelography and computed tomography led to prompt surgical decompression resulting in improvement of the patient's condition.
mesh_terms: D000368:Aged; D002404:Catheterization / Q000009:adverse effects; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology*; D006801:Humans; D009020:Morphine / Q000008:administration & dosage*; D010148:Intractable Pain / Q000188:drug therapy*; D013115:Spinal Canal / Q000473:pathology*
chemical_list: D009020:Morphine