Clobetasol propionate ointment reduces inflammation after cryotherapy.
A double-blind, randomized, placebo-controlled trial was carried out comparing the effects of clobetasol propionate ointment and the ointment base on the inflammation induced by cryotherapy of basal cell carcinomata and warts. A single application of the steroid was shown to be significantly better at reducing erythema, pain and swelling than the ointment base.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001623:Betamethasone / Q000031:analogs & derivatives*; D002280:Basal Cell Carcinoma / Q000601:surgery; D002986:Clinical Trials as Topic; D002990:Clobetasol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003452:Cryosurgery / Q000009:adverse effects*; D003872:Dermatitis / Q000209:etiology / Q000517:prevention & control*; D004311:Double-Blind Method; D004890:Erythema / Q000517:prevention & control; D006801:Humans; D008875:Middle Aged; D009824:Ointments; D012871:Skin Diseases / Q000601:surgery; D012878:Skin Neoplasms / Q000601:surgery; D014860:Warts / Q000601:surgery
D009824:Ointments; D001623:Betamethasone; D002990:Clobetasol