Misinterpretations of results and creation of "artifacts" in studies on developmental toxicity using systems simpler than in vivo systems.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000818:Animals; D001711:Biotransformation; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003470:Culture Media / Q000494:pharmacology; D046508:Culture Techniques / Q000379:methods; D004353:Drug Evaluation, Preclinical; D004622:Embryo, Mammalian / Q000187:drug effects; D005314:Embryonic and Fetal Development / Q000187:drug effects; D005189:False Positive Reactions; D051379:Mice; D009024:Morphogenesis / Q000187:drug effects; D009924:Organ Culture Techniques / Q000379:methods; D012107:Research Design; D012995:Solubility; D013723:Teratogens / Q000032:analysis* / Q000378:metabolism; D014116:Toxicology / Q000379:methods*
D003470:Culture Media; D013723:Teratogens