title: The lens epithelium contains glial fibrillary acidic protein (GFAP).
abstract: Both polyclonal and monoclonal antibodies to glial fibrillary acidic protein (GFAP) intensely immunostain the lens epithelium. Two-dimensional gels of mouse lens epithelium protein extracts reveal a protein which co-migrates with GFAP from spinal cord. A lens epithelial protein of approximately 50 000 MW on one-dimensional gels is immunoreactive with antiserum to GFAP (Hatfield et al. 1984). GFAP has been regarded as a protein unique to neuroglial cells but this study indicates that some cells of ectodermal origin (the lens epithelium) express GFAP.
mesh_terms: D000818:Animals; D001921:Brain / Q000166:cytology; D001923:Brain Chemistry; D004586:Electrophoresis / Q000379:methods; D004848:Epithelium / Q000032:analysis / Q000033:anatomy & histology; D005455:Fluorescent Antibody Technique; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis*; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D007908:Lens, Crystalline / Q000032:analysis* / Q000033:anatomy & histology; D051379:Mice
chemical_list: D005904:Glial Fibrillary Acidic Protein