Metabolic effects of conversion from cyclosporine to azathioprine in renal transplant recipients.
The metabolic effects of conversion from cyclosporine (Cys) to azathioprine were studied in 10 non-diabetic renal transplant recipients. Following conversion there was a significant improvement in renal function. There was no evidence of glucose intolerance pre-conversion, and no change in glucose metabolism following conversion. However, fasting cholesterol and triglyceride levels were significantly improved following conversion. The mechanism of this change and its significance needs further investigation.
D000328:Adult; D001379:Azathioprine / Q000008:administration & dosage*; D002784:Cholesterol / Q000097:blood; D003524:Cyclosporins / Q000008:administration & dosage*; D006801:Humans; D007668:Kidney / Q000502:physiology; D016030:Kidney Transplantation; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D003524:Cyclosporins; D014280:Triglycerides; D002784:Cholesterol; D001379:Azathioprine