Ultrasonography in the diagnosis and follow-up of hepatic sinusoidal dilatation.
Hepatic sinusoidal dilatation is a rare complication of oral contraceptive use. A 29-year-old woman who had been taking oral contraceptive pills for eight years was found to have persistently elevated erythrocyte sedimentation rates and alkaline phosphatase levels, hepatomegaly, diffuse hepatic sinusoidal dilatation, and a large nonhomogeneous hyperechogenic lesion in the right hepatic lobe. The abdominal ultrasonogram, liver size, erythrocyte sedimentation rates, and alkaline phosphatase levels reverted to normal within 24 months after discontinuing oral contraceptives. This case should encourage the use of abdominal ultrasonography in detection and follow-up of hepatic sinusoidal dilatation.
D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects; D004108:Dilatation, Pathologic / Q000139:chemically induced; D004338:Drug Combinations; D004997:Ethinyl Estradiol / Q000009:adverse effects; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008099:Liver / Q000098:blood supply* / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology*; D008234:Lynestrenol / Q000009:adverse effects; D008656:Mestranol / Q000009:adverse effects; D009644:Norgestrel / Q000009:adverse effects; D014463:Ultrasonography
D003277:Contraceptives, Oral, Combined; D004338:Drug Combinations; D009644:Norgestrel; D004997:Ethinyl Estradiol; C002746:Noracycline; D019304:Ethinyl Estradiol-Norgestrel Combination; D008656:Mestranol; D008234:Lynestrenol