[Atherosclerosis and the system of immunity].
The immunocompetent tissues were studied on the clinical and necropsy material, taking into consideration the development of sensitization to the atheorogenic lipids (VLDL, LDL). The signs of the sensitization to VLDL or LDL were observed in 83% patients. It is shown that the T-type immune response resulting from the sensitization to the lipoproteins is formed when the exacerbation of the atherosclerosis occurs. The vascular wall antigens in the lymph nodes regional to the arteries produce a local B-type immune response. The leucocyte migration test in combination with the staining of the blood smears for cation proteins can be used in the clinical practice for the detection of the atherosclerosis patients with a specific sensitization.
D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000276:immunology*; D002465:Cell Movement; D006801:Humans; D007107:Immune System / Q000276:immunology*; D007111:Immunity, Cellular; D007114:Immunization; D007121:Immunocompetence; D008077:Lipoproteins, LDL / Q000276:immunology; D008079:Lipoproteins, VLDL / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology
D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL
Ateroskleroz i sistema immuniteta.