[Modified ALTAB test in the diagnosis of exocrine pancreatic insufficiency].
The indirect estimation of chymotrypsin by the tubeless ALTAB-test was performed in 17 patients with well-defined exocrine pancreatic insufficiency, 10 of them after operation for chronic pancreatitis. In comparison with 12 healthy subjects the test proved to be a non-expensive, certain and specific method for detection of moderate and severe exocrine insufficiency. It exists positive correlations with the secretin-pancreocymine-test and with the maximal stimulable secretion of insulin. Therefore the ALTAB-test after operations with modified anatomy of the gastro-intestinal tract especially is able to substitute extensive testing of secretion in screening and controlling of progression. The value of the 3-hour serum level of PABA corresponds to the urine output within 6 hours. There are such advantages like independence from the kidney-function, avoidance of incomplete urine-collection and a considerable reduced test-time too.
D010129:4-Aminobenzoic Acid / Q000378:metabolism; D062365:Aminobenzoates; D002908:Chronic Disease; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis*; D006801:Humans; D010186:Pancreatic Function Tests / Q000379:methods*; D010195:Pancreatitis / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis*; D062366:para-Aminobenzoates
D062365:Aminobenzoates; D062366:para-Aminobenzoates; C020187:4-((N-Acetyl-L-tyrosyl)amino)benzoic acid; D010129:4-Aminobenzoic Acid
Der modifizierte ALTAB-Test in der Diagnostik der exokrinen Pankreasinsuffizienz.