Local administration of (15 S)-15-methyl PGF2 alpha for management of hypotonic post-partum hemorrhage.
Local (uterine) injection of (15 S)-15-methyl prostaglandin F2 alpha was highly effective as first-aid treatment for hypotonic post-partum hemorrhage and only 2% of the 50 treated patients required surgical intervention for such hemorrhage. Systemic side-effects did not occur, and besides the procedure is extremely simple as well as painless.
D000287:Administration, Topical; D002260:Carboprost / Q000627:therapeutic use*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007044:Hysterectomy; D006473:Postpartum Hemorrhage / Q000188:drug therapy*; D011247:Pregnancy; D011461:Prostaglandins F, Synthetic / Q000627:therapeutic use*; D014593:Uterine Inertia / Q000188:drug therapy*; D014599:Uterus / Q000187:drug effects
D011461:Prostaglandins F, Synthetic; D002260:Carboprost