A case of chronic myelogenous leukemia with 11q- in blast crisis with monoblastic differentiation.
We report a case of chronic myeloid leukemia in monoblastic blast crisis in which a deletion of chromosome 11 (11q-) was detected. Such a finding seems to provide further support to a relationship between this chromosome anomaly and monocytic proliferation.
D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D002872:Chromosome Deletion; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology; D009000:Monocytes / Q000473:pathology*