[Frequency of delta infections in Heidelberg].
The frequency of delta infection was studied in sera of 203 patients with acute hepatitis B, further 461 hepatitis B virus surface antigen-(HBsAg)-positive patients and 117 HBsAg-negative controls by determination of anti-delta by a competitive enzyme immunoassay. Sera have been collected since 1974. None of the sera of acute hepatitis B was anti-delta-positive whereas seven of the HBsAg-positive carriers were anti-delta-positive. Two of the anti-delta-positive patients had chronic hepatitis, four had liver cirrhosis. One of the anti-delta-positive patients with liver cirrhosis died of liver failure. Risk factors included Italian origin and parenteral routes of infection. All sera of 19 relatives of three anti-delta-positive index cases remained anti-delta-negative.
D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D002908:Chronic Disease; D003673:Defective Viruses / Q000276:immunology; D005260:Female; D005860:Germany, West; D006509:Hepatitis B / Q000453:epidemiology* / Q000276:immunology; D006511:Hepatitis B Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006518:Hepatitis Viruses / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D008103:Liver Cirrhosis / Q000276:immunology; D008297:Male; D006435:Renal Dialysis
D000914:Antibodies, Viral; D000956:Antigens, Viral; D006511:Hepatitis B Antigens; D006514:Hepatitis B Surface Antigens
Häufigkeit von Delta-Infektionen in Heidelberg.