[Achievements of molecular endocrinology and biochemistry of hormones and new approaches to the study and correction of endocrine disorders].
Considerable progress in a study of the molecular mechanisms of the hormone biological effect has shown that practically all hormones regulate metabolism in the body by influencing the cell genetic system. These fundamental results served as a basis for a rapid development of a new direction--molecular endocrinology. In recent years effective approaches that make it possible to penetrate the secret of human and animal gene structure have been worked out. The paper is concerned with the results of a study of nucleotide sequences of genes and mRNA of various protein hormones and an analysis of the importance of these developments for present-day endocrinology and biochemistry of hormones.
D000818:Animals; D004700:Endocrine System Diseases / Q000628:therapy*; D004704:Endocrinology / Q000639:trends*; D005809:Genes, Regulator; D005818:Genetic Engineering; D006728:Hormones / Q000235:genetics / Q000378:metabolism; D006801:Humans; D051379:Mice; D008957:Models, Genetic; D008967:Molecular Biology; D010455:Peptides / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics
D006728:Hormones; D010455:Peptides; D012333:RNA, Messenger
Uspekhi molekuliarnoĭ endokrinologii i biokhimii gormonov i novye podkhody k izucheniiu i korrektsii endokrinnykh narusheniĭ.