The gastrointestinal absorption of drugs in man: a review of current concepts and methods of investigation.
The various mechanisms which have been advanced to explain drug absorption are critically reviewed and the limitations of current theories are discussed. Various techniques for investigating drug absorption and transit through the gut are presented, and the results obtained with metoprolol are briefly considered to illustrate the potential of some of these methods.
D001834:Body Water / Q000378:metabolism; D005746:Gastric Emptying; D006801:Humans; D007408:Intestinal Absorption; D007700:Kinetics; D008790:Metoprolol / Q000378:metabolism; D010096:Oxprenolol / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*
D004364:Pharmaceutical Preparations; D010096:Oxprenolol; D008790:Metoprolol