Septicaemic low birthweight neonates treated with human antibodies to endotoxin.
In a double blind controlled study antilipopolysaccharide gammaglobulin given intramuscularly did not reduce mortality in low birthweight babies suffering from septicaemia. It did, however, reduce the recovery period of survivors from 310 to 120 hours.
D000907:Antibodies, Bacterial / Q000008:administration & dosage*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004731:Endotoxins / Q000276:immunology*; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008033:Limulus Test; D008070:Lipopolysaccharides / Q000276:immunology*; D008297:Male; D018805:Sepsis / Q000628:therapy*
D000907:Antibodies, Bacterial; D004731:Endotoxins; D008070:Lipopolysaccharides