title: Discovery of the hybridoma principle in 1968-69 immortalization of the specific antibody-producing cell by fusion with a lymphoma cell.
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D000921:Antibody-Producing Cells / Q000276:immunology*; D002459:Cell Fusion; D002478:Cells, Cultured; D006825:Hybridomas / Q000276:immunology*; D008223:Lymphoma / Q000276:immunology* / Q000473:pathology; D051379:Mice; D013154:Spleen / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal