[Superoxide dismutase and catalase activity in HeLa 229 cells infected with Chlamydia trachomatis].
Cytosolic superoxide dismutase (SOD) activity was found to increase with time during HeLa cell culture, this increase being due exclusively to Mn-SOD. Infection of the cells by Chlamydia trachomatis resulted in a further enhancement of this Mn-SOD activity, whereas cytosolic catalase activity was decreased in these infected cells. Superoxide (O-2.) being able to induce Mn-SOD and to inhibit catalase, these data suggest that Chlamydia trachomatis infection could be responsible for an increase in O-2. production by the infected HeLa cells.
D002374:Catalase / Q000378:metabolism*; D002690:Chlamydia Infections / Q000201:enzymology*; D002692:Chlamydia trachomatis; D006367:HeLa Cells / Q000201:enzymology*; D006801:Humans; D013482:Superoxide Dismutase / Q000378:metabolism*
D002374:Catalase; D013482:Superoxide Dismutase
Activités des superoxyde dismutases et de la catalase dans les cellules HeLa 229 infectées par Chlamydia trachomatis.