title: Minocycline in chronic abacterial prostatitis: a double-blind prospective trial.
abstract: In patients with chronic abacterial prostatitis, a double-blind trial of 3 months of treatment with minocycline 100 mg twice daily compared with diazepam 5 mg twice daily was undertaken. The percentage fall in polymorphonuclear leucocyte counts in the expressed prostatic secretions was much more marked after treatment with minocycline than with diazepam. Over a follow-up period of at least 12 months, further treatment was necessary in more patients originally treated with diazepam than with minocycline.
mesh_terms: D002986:Clinical Trials as Topic; D003975:Diazepam / Q000627:therapeutic use; D004311:Double-Blind Method; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008911:Minocycline / Q000627:therapeutic use*; D009504:Neutrophils; D011446:Prospective Studies; D011472:Prostatitis / Q000188:drug therapy*; D013754:Tetracyclines / Q000627:therapeutic use*
chemical_list: D013754:Tetracyclines; D008911:Minocycline; D003975:Diazepam