title: Effects of some DNA-ligands and of some mutagenic compounds on the induction of meiotic disomic or diploid yeast products.
abstract: Data were collected following the administration of various compounds to meiotic yeast cultures to investigate their effects on disomic or diploid induction. Epi chlorohydrin, actinomycin D, and 9-aminoacridine were unable to induce either diploidy or disomy. Ethyl methanesulphonate was active in inducing diploids, while hycanthone induced disomics. beta-Propiolactone, N-methyl-N'-nitro-N-nitro-soguanidine, and beta-naphtylamine were able to increase both disomy and diploidy.
mesh_terms: D004247:DNA; D008024:Ligands; D008540:Meiosis / Q000187:drug effects*; D009153:Mutagens / Q000633:toxicity*; D009630:Nondisjunction, Genetic; D011995:Recombination, Genetic / Q000187:drug effects*; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013172:Spores, Fungal; D013329:Structure-Activity Relationship
chemical_list: D008024:Ligands; D009153:Mutagens; D004247:DNA