A retrospective review of endophthalmitis due to coagulase-negative staphylococci.
We retrospectively reviewed 28 cases of postoperative endophthalmitis due to coagulase-negative staphylococci. There was an average delay between surgery and the acute presentation of 7 X 2 days (SD 3 X 3). All patients were treated with intraocular antibiotics (IOAB) or therapeutic vitrectomy with IOAB. In six of the 28 cases the organisms were resistant to gentamicin as measured by the Kirby-Bauer technique; none was resistant to cephalosporins. Isolates that had been stored by lyophilisation were reconstituted and tested by serial dilution; none was resistant to gentamicin, though two were borderline. The final visual acuity was 6/18 or better in 72% of the eyes.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002511:Cephalosporins / Q000494:pharmacology; D003030:Coagulase / Q000378:metabolism; D004352:Drug Resistance, Microbial; D009877:Endophthalmitis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D005839:Gentamicins / Q000494:pharmacology; D006801:Humans; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000150:complications*; D013210:Staphylococcus / Q000187:drug effects / Q000201:enzymology; D014792:Visual Acuity; D014821:Vitrectomy
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D003030:Coagulase; D005839:Gentamicins