Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast.
The MAT alpha 2 protein of budding yeast represses a set of genes; if the MATa1 protein is also present, a further set of genes is repressed. DNA sequence comparisons reveal a 20-base pair 'operator' sequence that is present in genes repressed by a1/alpha 2. A related, but distinct, sequence is found in genes repressed by alpha 2 alone.
D001483:Base Sequence; D004271:DNA, Fungal / Q000235:genetics*; D005786:Gene Expression Regulation; D005800:Genes, Fungal; D000072235:Mating Factor; D010455:Peptides / Q000235:genetics*; D011401:Promoter Regions, Genetic; D012097:Repressor Proteins / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014158:Transcription, Genetic
D004271:DNA, Fungal; D010455:Peptides; D012097:Repressor Proteins; D000072235:Mating Factor