The place of temocillin in the treatment of hospital infections.
Infection due to Gram-negative bacteria continues to be a common problem in the hospital environment, for which a wide variety of antibiotics is available. Among Enterobacteria, resistance is expressed most commonly via beta-lactamases. Temocillin is the first penicillin to show stability to beta-lactamases of Gram-negative bacteria, therefore it is in this type of infection that the initial assessments of temocillin should be made.
D002228:Carbenicillin / Q000378:metabolism; D002876:Chromosomes, Bacterial; D003428:Cross Infection / Q000188:drug therapy*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D006090:Gram-Negative Bacteria; D006801:Humans; D008802:Mezlocillin / Q000378:metabolism; D010403:Penicillin Resistance; D010406:Penicillins / Q000378:metabolism / Q000627:therapeutic use*; D010878:Piperacillin / Q000378:metabolism; D010957:Plasmids; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism
D010406:Penicillins; C031367:temocillin; D001618:beta-Lactamases; D002228:Carbenicillin; D008802:Mezlocillin; D010878:Piperacillin