The mutagenicity of dinitrochlorobenzene.
A sample of dinitrochlorobenzene, determined by gas-liquid chromatography and mass spectrometry to be greater than 98% pure, was tested in the Salmonella typhimurium plate assay. The chemical evoked a marked mutagenic response at all concentrations tested (3 to 150 micrograms per plate). These results confute the suitability of this agent for the treatment of benign skin disorders.
D000818:Animals; D002849:Chromatography, Gas; D004137:Dinitrochlorobenzene / Q000302:isolation & purification / Q000633:toxicity*; D008401:Gas Chromatography-Mass Spectrometry; D009152:Mutagenicity Tests; D009578:Nitrobenzenes / Q000633:toxicity*; D012486:Salmonella typhimurium / Q000187:drug effects
D004137:Dinitrochlorobenzene; D009578:Nitrobenzenes