title: Myelofibrosis arising in treated histiocytosis X.
abstract: Myelofibrosis, or fibrous replacement of hematopoietic bone marrow, is rarely encountered in pediatric patients. An unusual, reversible case arising in the setting of treated histiocytosis X is reported, a previously undescribed association. The clinical, pathologic, radiographic, and scintigraphic characteristics of myelofibrosis are reviewed.
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007223:Infant; D008297:Male; D010026:Osteosclerosis / Q000139:chemically induced / Q000175:diagnosis; D055728:Primary Myelofibrosis / Q000139:chemically induced* / Q000175:diagnosis / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging
chemical_list: D000970:Antineoplastic Agents