title: The time-distance recorder as a means of improving the accuracy of fetal blood flow measurements.
abstract: The influence of pulsatile diameter changes on calculation of volume flow has been studied. In vitro studies and an animal study were carried out with a real-time imaging and pulsed Doppler velocity measurement system. For precise pulsatile diameter information a wall motion tracking device was incorporated. Whereas in vitro a high degree of accuracy was found for the measurements of volume flow, this could not be substantiated in the descending aorta of the fetal lamb, in which Doppler volume flow differed between -7.5 and 17% from magnetic volume flow. In a clinical study the relative influence of various diameter approximations on calculated fetal aortic volume flow was assessed in 16 normal third trimester pregnancies. Depending on the selected diameter approximation method it appeared that differences from 19% underestimation to 9% overestimation in calculated volume flow could be obtained when reference was made to volume flow derived from diameter and velocity information.
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000502:physiology; D001783:Blood Flow Velocity; D005260:Female; D005333:Fetus / Q000502:physiology*; D006801:Humans; D011247:Pregnancy; D012039:Regional Blood Flow; D012756:Sheep / Q000502:physiology; D013997:Time Factors; D014465:Ultrasonics / Q000295:instrumentation; D014463:Ultrasonography / Q000295:instrumentation*; D014655:Vascular Resistance