PiZZ alpha 1-antitrypsin deficiency in a 20-week fetus.
Immunoperoxidase and electron microscopic studies of the liver of a 20-week fetus with PiZZ alpha 1-antitrypsin deficiency are described. The significance of the bile duct hypoplasia observed in the liver is discussed. The abnormal morphology of the jejunal mucosa is also described.
D003593:Cytoplasm / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005260:Female; D005315:Fetal Diseases / Q000201:enzymology / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007413:Intestinal Mucosa / Q000473:pathology; D007583:Jejunum / Q000473:pathology; D008099:Liver / Q000201:enzymology / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D010641:Phenotype; D011247:Pregnancy; D000515:alpha 1-Antitrypsin / Q000032:analysis; D019896:alpha 1-Antitrypsin Deficiency
D000515:alpha 1-Antitrypsin