[Study of the mechanism of luminol-dependent chemiluminescence of lymphocytes induced by immune complexes].
Intensification of luminol-dependent chemiluminescence of nonadhesive mouse splenocytes affected by immune complexes has been shown to depend on B-lymphocytes. As shown by the inhibition analysis, this process is, probably, dependent on the formation of hydroxyl radicals of singlet oxygen and on the condition of cytoskeleton.
D000818:Animals; D000936:Antigen-Antibody Complex / Q000276:immunology*; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D002478:Cells, Cultured; D005609:Free Radicals; D008163:Luminescent Measurements; D008165:Luminol / Q000494:pharmacology*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D051379:Mice; D008819:Mice, Nude; D011724:Pyridazines / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
D000936:Antigen-Antibody Complex; D005609:Free Radicals; D011724:Pyridazines; D008165:Luminol
Izuchenie mekhanizma liuminolzavisimoĭ khemiliuminestsentsii limfotsitov pod vliianiem immunnykh kompleksov.