title: Bioengineering changes in spastic cerebral palsy groups following cerebellar stimulation.
abstract: Quantitative bioengineering tests were performed on 30 spastic cerebral palsy (CP) patients who underwent chronic cerebellar stimulation (CCS) using the fully implantable pulse generator (Neurolith 601, 1.1-1.8 microC/cm2/phase). Using respiratory inductive plethysmography to measure 8 patients with paroxysmal and/or ataxic breathing patterns, 5 were shown to revert to normal with 3 others markedly improved within 5 months of CCS. Compliance testing of the ankle was performed on 4 patients who showed improvement in 9 of the 16 tests performed. Motor performance ability was evaluated with 9 comprehensive tests in 17 patients. Following 1-2 weeks of CCS, 52% showed performance increases greater than 10%, increasing to 62% during the first year.
mesh_terms: D002531:Cerebellum / Q000503:physiopathology*; D002547:Cerebral Palsy / Q000503:physiopathology / Q000628:therapy*; D004599:Electric Stimulation Therapy / Q000295:instrumentation; D004567:Electrodes, Implanted; D006801:Humans; D009119:Muscle Contraction; D009128:Muscle Spasticity / Q000503:physiopathology / Q000628:therapy; D011597:Psychomotor Performance; D012119:Respiration