Toxic ricin demonstrates a dual dental projection.
Toxic ricin was used to study the central distribution of dental afferents in the cat. Following intrapulpal ricin injections ganglion cell degeneration is seen in the II and III ganglion divisions. Central argyrophilic degeneration occurs in the dorsal portion of all ipsilateral trigeminal nuclei. Ventral degeneration is seen in the pars interpolaris and pars caudalis. No contralateral degeneration was observed. The results are discussed with regard to previous studies of the central location of dental afferents.
D000818:Animals; D002415:Cats; D003782:Dental Pulp / Q000294:innervation*; D006735:Horseradish Peroxidase; D009445:Neuroanatomy / Q000379:methods; D009475:Neurons, Afferent; D012276:Ricin; D014275:Trigeminal Caudal Nucleus / Q000033:anatomy & histology; D012668:Trigeminal Ganglion / Q000033:anatomy & histology; D014276:Trigeminal Nerve / Q000033:anatomy & histology*; D014278:Trigeminal Nuclei / Q000033:anatomy & histology*
D012276:Ricin; D006735:Horseradish Peroxidase