Fish melanin-concentrating hormone disperses melanin in amphibian melanophores.
Melanin-concentrating hormone (MCH), which was isolated from salmon pituitary and caused melanin concentration in fish scale melanophores, has been tested on cultured chromatophores of an amphibian, the bullfrog tadpole. MCH induced dispersion of melanin in cultured melanophores of the tadpole. The duration of the dispersing effect of MCH was relatively short compared with that of alpha-melanocyte-stimulating hormone (alpha-MSH). MCH also induced the concentration of cultured iridophores of bullfrog tadpole.
D000818:Animals; D002478:Cells, Cultured; D005399:Fishes; D007028:Hypothalamic Hormones; D007700:Kinetics; D008543:Melanins / Q000378:metabolism* / Q000494:pharmacology*; D009074:Melanocyte-Stimulating Hormones / Q000494:pharmacology; D008547:Melanophores / Q000187:drug effects / Q000378:metabolism*; D010907:Pituitary Hormones / Q000494:pharmacology*; D011892:Rana catesbeiana; D012474:Salmon / Q000378:metabolism; D014982:Xenopus laevis
D007028:Hypothalamic Hormones; D008543:Melanins; D010907:Pituitary Hormones; C019463:melanin-concentrating hormone; D009074:Melanocyte-Stimulating Hormones