Augmentation of interleukin-2 production and delayed hypersensitivity in mice infected with Mycobacterium bovis and fed a diet supplemented with vitamin A acetate.
High-dose Mycobacterium bovis-infected mice fed a vitamin A acetate-supplemented diet developed a positive skin reaction to purified protein derivative of mycobacteria, and their spleen cells showed an increased IL-2 production in vitro.
D000818:Animals; D004224:Diterpenes; D005260:Female; D006968:Hypersensitivity, Delayed; D007376:Interleukin-2 / Q000096:biosynthesis*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009163:Mycobacterium bovis; D000084562:Retinyl Esters; D013601:T-Lymphocytes / Q000276:immunology; D014376:Tuberculosis / Q000276:immunology*; D014801:Vitamin A / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology
D004224:Diterpenes; D007376:Interleukin-2; D000084562:Retinyl Esters; D014801:Vitamin A; C009166:retinol acetate