Pepsinogen isozymes in Borrmann IV type gastric carcinoma.
Immunoperoxidase staining for human group I and group II pepsinogens (PG I, PG II) was performed on stomachs including surgically removed 42 Borrmann IV type gastric carcinomas (B-IV), 6 duodenal ulcers and 6 autopsy cases of traffic accident. Besides, 8 surgical cases of B-IV were examined by polyacrylamide gel electrophoresis (PAGE). All 8 cases examined by PAGE showed positive finding for at least one pepsinogen isozyme. In male, 19/19 were positive while in female 21/23 were positive for PG I and/or PG II by the immuno-peroxidase method.
D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer / Q000201:enzymology; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007527:Isoenzymes / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010435:Pepsinogens / Q000032:analysis*; D010447:Peptide Hydrolases / Q000032:analysis; D013274:Stomach Neoplasms / Q000201:enzymology*
D007527:Isoenzymes; D010435:Pepsinogens; D010447:Peptide Hydrolases