Perfluorochemical emulsion oxygen transport fluids: a clinical review.
Perfluorochemical liquids are inert, immiscible in water, and have approximately 20 times the solubility for oxygen and carbon dioxide as does water. When emulsified in a normal saline solution, they can act as an oxygen-transporting resuscitation fluid. Fluosol-DA 20% is the first perfluorochemical emulsion to be studied clinically. It can supplement oxygen transport in anemic patients, but no control study has as yet determined its clinical effectiveness.
D000740:Anemia / Q000628:therapy*; D001802:Blood Substitutes / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004338:Drug Combinations / Q000009:adverse effects / Q000627:therapeutic use; D005466:Fluorocarbons / Q000009:adverse effects / Q000627:therapeutic use*; D006470:Hemorrhage / Q000628:therapy; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives; D007431:Intraoperative Complications / Q000628:therapy; D013514:Surgical Procedures, Operative
D001802:Blood Substitutes; D004338:Drug Combinations; D005466:Fluorocarbons; D006895:Hydroxyethyl Starch Derivatives; C017323:glucose, glycerol, hydroxyethyl starch, perfluorodecalin, perfluorotripropylamine, pluronic F-68, salts, yolk phospholipids drug combination