Effects of the virulence plasmid ColV, I-K94 on the sensitivity of Escherichia coli to putative environmental inhibitory agents.
Derivatives of Escherichia coli carrying the virulence plasmid, ColV, I-K94 were more resistant than the ColV- parents to phage Mel but were more sensitive to the hydrophobic inhibitors deoxycholate, erythromycin and lysozyme. The basis for these changes in sensitivity has been examined in ColV+ mutants with altered colicin or VmpA protein levels and in ColV+ strains with repressed transfer properties.
D001425:Bacterial Outer Membrane Proteins / Q000378:metabolism; D001435:Bacteriophages / Q000502:physiology*; D003087:Colicins / Q000494:pharmacology; D003840:Deoxycholic Acid / Q000494:pharmacology*; D004917:Erythromycin / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000472:pathogenicity; D009113:Muramidase / Q000494:pharmacology*; D010957:Plasmids
D001425:Bacterial Outer Membrane Proteins; D003087:Colicins; D003840:Deoxycholic Acid; D004917:Erythromycin; D009113:Muramidase