[Effect of vitamin D2 on the monooxygenase activity of the rat liver].
Stimulation of lipid peroxidation in the liver microsomal fraction and alteration in the xenobiotic metabolism were found within twelve hrs after a single vitamin D2 administration (960,000 MU/kg) into male rats. The effects observed appear to occur due to the vitamin D2 prooxidative properties.
D000818:Animals; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004872:Ergocalciferols / Q000494:pharmacology*; D008054:Lipid Peroxides / Q000378:metabolism*; D008099:Liver / Q000201:enzymology* / Q000378:metabolism; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D010084:Oxidation-Reduction; D051381:Rats
D004872:Ergocalciferols; D008054:Lipid Peroxides; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases
Vliianie vitamina D2 na aktivnost' monooksigenaz pecheni krys.