title: Step 1 1/2 therapy for the treatment of hypertension.
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004232:Diuretics / Q000627:therapeutic use; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008788:Metolazone / Q000627:therapeutic use; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D013148:Spironolactone / Q000627:therapeutic use*
chemical_list: D000959:Antihypertensive Agents; D004232:Diuretics; D004338:Drug Combinations; C016210:buthiazide, spironolactone drug combination; D006852:Hydrochlorothiazide; D013148:Spironolactone; D011188:Potassium; D008788:Metolazone