[Dynamics of the antihemagglutinin level in annual human immunization with inactivated influenza vaccines].
Inactivated influenza vaccines are classified according to the types of antihemagglutinin response after annual revaccination of people with inactivated influenza vaccines carried out for 3 successive years. The results of analysis show that in response to annual revaccination with inactivated vaccine up to 80% of the vaccinees develop no positive changes in antihemagglutinin titres. An experiment using a liver moderately attenuated vaccine after a single immunization with an inactivated vaccine demonstrated that 64.7% vaccinees would not be involved in the epidemic process at all and 11.5% would be involved at the level of asymptomatic infection. The remaining portion (23.8%), also involved in the epidemic process after immunization with inactivated vaccine, apparently requires additional immunological protection. The results of the above study indicate the inefficacy of annual vaccination of the same subjects with the same inactivated influenza vaccine.
D000328:Adult; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D006389:Hemagglutinins, Viral / Q000276:immunology*; D006801:Humans; D007115:Immunization Schedule; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000145:classification / Q000276:immunology*; D013997:Time Factors; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000145:classification / Q000276:immunology
D000888:Antibodies, Anti-Idiotypic; D006389:Hemagglutinins, Viral; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated
Dinamika urovnia antigemaggliutininov v usloviiakh ezhegodnoĭ immunizatsii liudeĭ grippoznymi inaktivirovannymi vaktsinami.