Dual radiation action and the initial slope of survival curves.
The concepts and tools of the Theory of Dual Radiation Action (e.g., proximity functions and gamma distributions) are outlined, and their connection to single-event cell inactivation is exemplified by an analysis and interpretation of the cross-section data obtained by Todd. It is shown that the biological effect of individual charged particles is dominated by the combined action of a few delta rays.
D000818:Animals; D002467:Cell Nucleus / Q000528:radiation effects; D002470:Cell Survival / Q000528:radiation effects*; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D011829:Radiation Dosage; D011853:Radiobiology; D012062:Relative Biological Effectiveness