Total and IgE antibody levels following booster immunization with aluminum absorbed and nonabsorbed tetanus toxoid in humans.
Total and IgE serum antibodies to tetanus toxoid were measured in 32 healthy adults, 3-4 weeks following booster immunization with either plain or aluminum hydroxide-absorbed tetanus toxoid. Whereas no difference in the total antibody values was observed, the level of anti-tetanus toxoid IgE antibodies was significantly higher in the group boostered with the adjuvanted vaccine.
D000328:Adult; D000368:Aged; D000535:Aluminum / Q000276:immunology; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D002118:Calcium / Q000494:pharmacology; D006801:Humans; D007117:Immunization, Secondary; D007073:Immunoglobulin E / Q000276:immunology*; D007164:Immunosorbents; D008875:Middle Aged; D013745:Tetanus Toxoid / Q000276:immunology*
D000888:Antibodies, Anti-Idiotypic; D007164:Immunosorbents; D013745:Tetanus Toxoid; D007073:Immunoglobulin E; D000535:Aluminum; D002118:Calcium