title: Anatomical basis of intervertebral disc puncture with chemonucleolysis.
abstract: Transparietal puncture of the lumbar intervertebral discs is done to achieve enzymatic nucleolysis. This technique requires firm understanding of the morphology and topography of the anatomical structures traversed by the needle as well as those to be avoided. Vertebral disc puncture with chemonucleolysis has been done by the author for four years. The aim of this study was to identify the parameters allowing facilitation of this procedure, thereby leading to a decreased X-ray exposure. To achieve this goal an analytical study of the target structure and its neurovascular, osseous and visceral relations was carried out. The results of this study led to practical conclusions regarding especially the parameters of disc puncture, their preoperative identification and the risks encountered in case of erroneous puncture.
mesh_terms: D002917:Chymopapain / Q000627:therapeutic use*; D010450:Endopeptidases / Q000627:therapeutic use*; D006801:Humans; D007403:Intervertebral Disc / Q000033:anatomy & histology*; D007405:Intervertebral Disc Displacement / Q000628:therapy*; D013127:Spinal Nerves / Q000033:anatomy & histology; D013129:Spinal Puncture; D013131:Spine / Q000098:blood supply; D014057:Tomography, X-Ray Computed
chemical_list: D010450:Endopeptidases; D002917:Chymopapain