title: [Antiarrhythmic agents in tinnitus treatment].
abstract: The treatment of tinnitus patients is a major problem in ENT. This depends on the fact that no objective parameter exists for this symptom. Therefore, every treatment schedule should meet the criteria of a rational tinnitus treatment. The value of lidocaine in the management of the tinnitus patient was assessed in a randomised blind-controlled cross-over trial. 20 patients with sensorineural hearing loss of different kinds and a well defined tinnitus were treated by an intravenous infusion of lidocaine. 13 patients reported a tinnitus suppression of more than 50 per cent, whereas there was no response with saline. These subjective changes were accompanied by BERA alterations such as a reversible lengthening of central conduction time without hearing impairment. The mechanism of action of lidocaine in tinnitus is discussed according to electrophysiological hypotheses.
mesh_terms: D002986:Clinical Trials as Topic; D006319:Hearing Loss, Sensorineural / Q000150:complications; D006801:Humans; D007263:Infusions, Parenteral; D008012:Lidocaine / Q000627:therapeutic use*; D014012:Tinnitus / Q000188:drug therapy*
chemical_list: D008012:Lidocaine
vernacular_title: Antiarrhythmika in der Tinnitusbehandlung.