Effect of positive-pressure breathing on cardiovascular and thermoregulatory responses to exercise.
Five healthy male volunteers performed 20 min of both seated and supine cycle-ergometer exercise (intensity, 50% maximal O2 uptake) in a warm environment (Tdb = 30 degrees C, relative humidity = 40-50%) with and without breathing 10 cmH2O of continuous positive airway pressure (CPAP). The final esophageal temperature (Tes) at the end of 20 min of seated exercise was significantly higher during CPAP (mean difference = 0.18 +/- 0.04 degree C, P less than 0.05) compared with control breathing (C). The Tes threshold for forearm vasodilation was significantly higher (P less than 0.05) during seated CPAP exercise than C (C = 37.16 +/- 0.13 degrees C, CPAP = 37.38 + 0.12 degree C). The highest forearm blood flow (FBF) at the end of exercise was significantly lower (P less than 0.05) during seated exercise with CPAP (mean +/- SE % difference from C = -30.8 +/- 5.8%). During supine exercise, there were no significant differences in the Tes threshold, highest FBF, or final Tes with CPAP compared with C. The added strain on the cardiovascular system produced by CPAP during seated exercise in the heat interacts with body thermoregulation as evidenced by elevated vasodilation thresholds, reduced peak FBF, and slightly higher final esophageal temperatures.
D000328:Adult; D001794:Blood Pressure; D001810:Blood Volume; D001831:Body Temperature; D001833:Body Temperature Regulation; D002302:Cardiac Output; D004947:Esophagus / Q000502:physiology; D005542:Forearm / Q000098:blood supply; D006339:Heart Rate; D006439:Hemodynamics; D006358:Hot Temperature; D006801:Humans; D008297:Male; D005082:Physical Exertion; D011175:Positive-Pressure Respiration; D011187:Posture; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply; D014664:Vasodilation