[Inactivation of non-syngeneic hematopoietic stem cells by mouse lymphocytes after long-term exposure to tritium oxide].
A study was made of functional activity of lymphocytes, which inactivated nonsyngeneic colony-forming units (CFU) in allogenous and xenogenous interaction systems, at different times after long-term action of tritium oxide in a cumulative dose of approximately 9 Gy. The function of these lymphocytes was depressed during the first months after termination of exposure while at later times it exceeded the control level. The consequences of the interaction between lymphocytes and nonsyngeneic CFU were also studied in this work.
D000818:Animals; D016026:Bone Marrow Transplantation; D002452:Cell Count; D003114:Colony-Forming Units Assay; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000276:immunology*; D008198:Lymph Nodes / Q000637:transplantation; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011833:Radiation Injuries, Experimental / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains; D013601:T-Lymphocytes / Q000276:immunology / Q000528:radiation effects*; D013997:Time Factors; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous; D014316:Tritium; D014867:Water
D014867:Water; D014316:Tritium; C033961:tritium oxide
Inaktivatsiia T-limfotsitami mysheĭ nesingennykh stvolovykh krovetvornykh kletok posle dlitel'nogo deĭstviia okisi tritiia.