title: Elastin covalent structure as determined by solid phase amino acid sequencing.
abstract: The amino acid sequences of 16 large tryptic fragments of aortic tropoelastin have been determined establishing the presence of several repeating structures: GVP, GGVP, PGVGV, PGVGVA, and AGVPGFGVG. The methodologies for achieving these results by solid phase sequencing are reviewed and also the possible biologic significance of the unusual primary structures of elastin are discussed.
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D004549:Elastin / Q000031:analogs & derivatives*; D010446:Peptide Fragments / Q000032:analysis*; D013552:Swine; D014333:Tropoelastin / Q000032:analysis* / Q000302:isolation & purification
chemical_list: D000596:Amino Acids; D010446:Peptide Fragments; D014333:Tropoelastin; D004549:Elastin