title: Cultured epithelium as a skin substitute.
abstract: The history of techniques for the replacement of lost skin is reviewed, including the current research in the use of synthetic dermal substitutes, skin allografts and immunosuppression, and tissue-cultured epithelial autografts. Developments in each of these three areas are encouraging steps toward the development of a skin substitute that would be immediately available for coverage of even massive areas of skin loss.
mesh_terms: D001187:Artificial Organs; D002056:Burns / Q000601:surgery; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D004848:Epithelium; D005260:Female; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D008567:Membranes, Artificial; D012867:Skin / Q000293:injuries*; D016038:Skin Transplantation; D013518:Surgery, Plastic; D014182:Transplantation, Autologous; D014945:Wound Healing
chemical_list: D008567:Membranes, Artificial