Drug-induced lupus. Genetic, clinical, and laboratory features.
Drug-induced lupus is a disorder similar to idiopathic systemic lupus erythematosus in terms of manifestations. However, these entities have significant serologic and clinical differences, which call into question the concept that they represent an identical disease process. Nonetheless, further research into the drug-induced disease will enhance our understanding and management of this clinically significant iatrogenic disease and will likely contribute to our comprehension of the pathogenesis of autoimmunity.
D000368:Aged; D000974:Antibodies, Antinuclear / Q000032:analysis; D003937:Diagnosis, Differential; D006801:Humans; D006830:Hydralazine / Q000009:adverse effects; D007136:Immunoglobulins / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis / Q000276:immunology; D011342:Procainamide / Q000009:adverse effects; D012306:Risk; D013997:Time Factors
D000974:Antibodies, Antinuclear; D007136:Immunoglobulins; D006830:Hydralazine; D011342:Procainamide