Marrow transplantation for pancytopenia in dyskeratosis congenita.
A 33-year-old man with dyskeratosis congenita received a marrow transplant to treat severe pancytopenia. The graft was successful-, but the patient developed severe acute graft-versus-host-disease grade IV and died 51 days postgrafting. - The outcome of transplantation in dyskeratosis congenita is compared to that in Fanconi's anaemia due to the resemblance of both diseases in some aspects.
D000328:Adult; D016026:Bone Marrow Transplantation; D006801:Humans; D008297:Male; D010198:Pancytopenia / Q000150:complications / Q000628:therapy*; D010859:Pigmentation Disorders / Q000150:complications / Q000235:genetics*; D012871:Skin Diseases / Q000150:complications / Q000235:genetics*