title: Human insulin: a double-blind clinical study of its effectiveness.
abstract: Over a two-year period, 88 patients were evaluated in a double-blind study of human insulin (recombinant DNA origin) and Iletin II pork insulin. Patient follow-up was done throughout the program by glycohemoglobin assays and self-monitoring of blood glucose levels. The C peptides were studied before and after a test meal of Sustacal. Insulin antibody determinations were made regularly. Dietary management was supervised throughout the study.
mesh_terms: D000906:Antibodies / Q000032:analysis; D001786:Blood Glucose / Q000032:analysis; D002096:C-Peptide / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D002986:Clinical Trials as Topic; D004274:DNA, Recombinant; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy* / Q000276:immunology; D003927:Diet, Diabetic; D004311:Double-Blind Method; D006801:Humans; D007328:Insulin / Q000276:immunology / Q000627:therapeutic use*; D012648:Self Care
chemical_list: D000906:Antibodies; D001786:Blood Glucose; D002096:C-Peptide; D004274:DNA, Recombinant; D007328:Insulin; D002784:Cholesterol