The effect of topical indomethacin on acute pressure elevation of laser trabeculoplasty in capsular glaucoma.
In this controlled study 24 phakic patients with capsular glaucoma received a 5-drop loading dose of topical 1.0% indomethacin on the eye to be treated and the fellow eye prior to argon laser trabeculoplasty and post-operatively every 3 h to the end of the day. A control group consisted of 25 phakic eyes with capsular glaucoma which were lasered without indomethacin drops. There were no statistically significant differences between the groups in the post-operative mean intraocular pressures (IOP) and mean corrected changes in IOP immediately and one month after laser treatment. However, no eyes in the indomethacin treated group showed a true pressure rise greater than or equal to 10 mmHg whereas 4 eyes in the control group did (P = 0.1).
D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007213:Indomethacin / Q000494:pharmacology*; D007429:Intraocular Pressure / Q000187:drug effects*; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control; D011292:Premedication; D014129:Trabecular Meshwork / Q000601:surgery*
D009883:Ophthalmic Solutions; D007213:Indomethacin