Does cervical ripening with PGE2 affect subsequent uterine activity in labour?
Uterine activity was measured quantitatively during subsequent labor after prostaglandin E2 gel (PGE2). Thirty primigravidae with a low Bishop score were included in this randomized double-blind study. Fewer women who received PGE2 required subsequent surgical induction. The pattern of uterine activity was different. Cervical dilatation was achieved with less uterine activity in the PGE2 group, especially during the shorter latent phase.
D000328:Adult; D002584:Cervix Uteri / Q000187:drug effects*; D002986:Clinical Trials as Topic; D015232:Dinoprostone; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007751:Labor, Induced; D010298:Parity; D011247:Pregnancy; D011458:Prostaglandins E / Q000494:pharmacology*; D014590:Uterine Contraction / Q000187:drug effects*
D011458:Prostaglandins E; D015232:Dinoprostone