title: [Toxicity of etmozin under extreme conditions].
abstract: A study was made of the toxicity of etmozine injected into rats of both sexes intraperitoneally under usual conditions, into overheated rats, into rats adapted to pressure chamber hypoxia, and into rats preadapted to pressure chamber hypoxia. It was established that etmozine toxity in the overheated rats significantly lessened as compared to that in intact animals, whereas in the rats adapted to pressure chamber hypoxia and in the overheated rats preadapted to pressure chamber hypoxia, it significantly rose.
mesh_terms: D000222:Adaptation, Physiological / Q000187:drug effects; D000531:Altitude; D000818:Animals; D001273:Atmosphere Exposure Chambers; D005260:Female; D006358:Hot Temperature / Q000009:adverse effects; D000860:Hypoxia / Q000503:physiopathology; D007928:Lethal Dose 50; D008297:Male; D016293:Moricizine; D010640:Phenothiazines / Q000633:toxicity*; D051381:Rats; D013312:Stress, Physiological / Q000503:physiopathology*
chemical_list: D010640:Phenothiazines; D016293:Moricizine
vernacular_title: Izuchenie toksichnosti étmozina v ékstremal'nykh usloviiakh.