[Synthesis and pharmacologic activity of derivatives of 3-aminopropiophenone and 3-aminomethylcamphor].
As a part of a research on analgesic compounds 0-(4-methoxyphenyl)carbamoyl-3-aminopropiophenone oximes, 0-(4-methoxyphenyl)-carbamoyl-3-aminomethylcamphor oximes and 4-(4-methoxyphenyl)semicarbazones of 3-aminopropiophenones were prepared. The analgesic activity of these compounds was tested and the results of pharmacological screening are discussed.
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis*; D001522:Behavior, Animal / Q000187:drug effects; D002164:Camphor / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D002490:Central Nervous System / Q000187:drug effects; D002626:Chemistry, Pharmaceutical; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011427:Propiophenones / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011427:Propiophenones; D002164:Camphor
Sintesi ed attività farmacologica di derivati di 3-aminopropiofenoni e di 3-aminometilcanfore.