title: [Value of the assay of cholinesterase activity in superficial biopsies of the rectum in the diagnosis of Hirschsprung's disease].
abstract: Cholinesterase activity have been estimated in rectal biopsies of 19 children with Hirschsprung's disease and 80 normal children. A high level of acetyl-cholinesterase is a strong argument for the diagnosis of aganglionosis. However the ratio acetylcholinesterase over butyrylcholinesterase seems to be a better sign allowing a right diagnosis in 99% of the cases.
mesh_terms: D001706:Biopsy; D002802:Cholinesterases / Q000378:metabolism*; D004796:Clinical Enzyme Tests; D005260:Female; D006627:Hirschsprung Disease / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012007:Rectum / Q000201:enzymology* / Q000473:pathology
chemical_list: D002802:Cholinesterases
vernacular_title: Intérêt du dosage de l'activité cholinestérasique au niveau des biopsies superficielles du rectum dans le diagnostic de la maladie de Hirschsprung.