title: [Current immunological aspects of allergic contact dermatitis].
abstract: We give a review of the function of Langerhans' cells and ETAF as well as the influence of UVB irradiation on the presentation of antigens. We than discuss some evidences for the possible involvement of cytochrome P-450 in the processing of antigens (parallelism between carcinogenesis and immunogenicity induced by aromatic hydrocarbons, high inducibility of cytochrome P-450 dependent enzyme activity in human monocytes, significance of compounds with quinone structure as allergens and carcinogenic agents.
mesh_terms: D000818:Animals; D003577:Cytochrome P-450 Enzyme System; D003877:Dermatitis, Contact / Q000276:immunology*; D000949:Histocompatibility Antigens Class II; D006801:Humans; D007107:Immune System / Q000528:radiation effects; D007375:Interleukin-1 / Q000276:immunology; D007801:Langerhans Cells / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D051379:Mice; D014466:Ultraviolet Rays
chemical_list: D000949:Histocompatibility Antigens Class II; D007375:Interleukin-1; D003577:Cytochrome P-450 Enzyme System
vernacular_title: Neue immunologische Aspekte der allergischen Kontakt-Dermatitis.