[Elimination of syngeneic lymphoma cells from a mouse bone marrow suspension using immune cytotoxic lymphocytes sensitized in vitro].
Murine splenocytes were cultivated with syngenic EL-4 lymphoma cells in the presence of interleukin-2 to obtain cytotoxic antileukemic lymphocytes. It was shown that the use of cytotoxic lymphocytes helped killing completely syngenic lymphoma cells in the mixture of bone marrow and EL-4 cells, spleen colony-forming hemopoietic predecessor cells being retained.
D000818:Animals; D001854:Bone Marrow Cells; D066298:In Vitro Techniques; D007376:Interleukin-2 / Q000494:pharmacology; D007694:Killer Cells, Natural / Q000276:immunology*; D008223:Lymphoma / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL
D007376:Interleukin-2
Eliminatsiia singennykh kletok limfoma iz suspenzii kostnogo mozga mysheĭ s pomoshch'iu immunnykh tsitotoksicheskikh limfotsitov, sensibilizirovannykh in vitro.