In vitro antibacterial activity of SK&F 88070 against aerobic gram-positive and gram-negative cocci and Haemophilus influenzae.
The inhibitory activity of SK&F 88070, a cephalosporin whose kinetic characteristics in animals suggest the possibility of once-daily doses, was determined against 345 clinical isolates, and results were compared with the activities of ceftizoxime, ceftriaxone, moxalactam, methicillin, and ampicillin. The spectrum of SK&F 88070 is similar to that of ceftizoxime.
D000667:Ampicillin / Q000494:pharmacology; D015281:Cefmenoxime / Q000031:analogs & derivatives*; D002439:Cefotaxime / Q000031:analogs & derivatives / Q000494:pharmacology; D015296:Ceftizoxime; D002443:Ceftriaxone / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology*; D006088:Gram-Negative Aerobic Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006193:Haemophilus influenzae / Q000187:drug effects*; D008712:Methicillin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009070:Moxalactam / Q000494:pharmacology
D002511:Cephalosporins; D002443:Ceftriaxone; D000667:Ampicillin; C041591:SK&F 88070; D015296:Ceftizoxime; D015281:Cefmenoxime; D002439:Cefotaxime; D008712:Methicillin; D009070:Moxalactam