title: Computed tomography and magnetic resonance imaging in late-onset globoid cell leukodystrophy (Krabbe disease).
abstract: A five-year-old white male presented with a history of progressive loss of vision that was subsequently followed by progressive corticospinal dysfunction. Evaluation revealed the presence of leukodystrophy which was confirmed by a deficiency of the enzyme, galactosylceramide beta-galactosidase. We present the clinical, computed tomographic, and magnetic resonance imaging features of this late-onset form of globoid cell leukodystrophy.
mesh_terms: D001284:Atrophy; D001921:Brain / Q000473:pathology; D002675:Child, Preschool; D006801:Humans; D007965:Leukodystrophy, Globoid Cell / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed