The therapy of Adie's syndrome with dilute pilocarpine hydrochloride solutions.
Impressed by the benefit two patients with Adie's Syndrome derived from topical 0.1% pilocarpine therapy, we performed the present study to examine the measurable effects of 0.1% pilocarpine in several patients with this syndrome. Our study suggests those patients with Adie's Syndrome who lack stereoacuity may benefit from long term therapy with dilute pilocarpine if their stereoacuity may benefit from long term therapy with dilute pilocarpine if their stereoacuity improves following a single drop of 0.1% pilocarpine. Therefore, we recommend measuring stereoacuity during pupil diagnostic testing with 0.1% pilocarpine hydrochloride. Potential problems concerning medical therapy of Adie's Syndrome with parasympathomimetics are discussed.
D000270:Adie Syndrome / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009883:Ophthalmic Solutions; D010862:Pilocarpine / Q000008:administration & dosage*; D012025:Reflex, Pupillary / Q000187:drug effects*
D009883:Ophthalmic Solutions; D010862:Pilocarpine