A 14;19 translocation in B-cell chronic lymphocytic leukemia: a new recurring chromosome aberration.
Four of 30 patients with a diagnosis of B-CLL or prolymphocytic transformation of CLL, who had an adequate cytogenetic analysis, had abnormalities involving 14q32. Three of the 4 had a translocation involving chr. 19; in 2 of them it appeared to be t(14;19) (q32;q13.1). The third patient probably had the same translocation. All 3 patients had received therapy prior to cytogenetic analysis.
D000328:Adult; D001402:B-Lymphocytes; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D002901:Chromosomes, Human, 13-15; D002903:Chromosomes, Human, 19-20; D006801:Humans; D007621:Karyotyping; D007945:Leukemia, Lymphoid / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic