Cortical anomalies in brains of New Zealand mice: a neuropathologic model of dyslexia?
Cortical anomalies have been reported in the brains of dyslexic individuals. In addition, dyslexic and left-handed individuals have a higher than expected rate of some immune-related diseases. The possible association between immune and cerebrocortical pathology was investigated in the immune-defective New Zealand Black mouse and its hybrid with the New Zealand White mouse. Structural anomalies similar to those present in the dyslexic brain were seen in the brains of these mice.
D000818:Animals; D001327:Autoimmune Diseases / Q000473:pathology*; D002540:Cerebral Cortex / Q000473:pathology*; D004195:Disease Models, Animal; D004410:Dyslexia / Q000473:pathology*; D005260:Female; D008297:Male; D051379:Mice; D008814:Mice, Inbred NZB / Q000033:anatomy & histology*