Acquired immunodeficiency syndrome (AIDS) in an economically disadvantaged population.
Forty patients with acquired immunodeficiency syndrome (AIDS), 70% of whom were intravenous drug abusers (IVDAs), were seen over a 20-month period (July 1, 1981, through Feb 28, 1983). Most of the patients came from two inner-city sections of New York City and from nearby correctional facilities. Eighty-five percent of the patients were black or Hispanic; only 15% were white. Unique features of AIDS in this mostly heterosexual population were the high incidence of opportunistic infections (90% of the patients), the low incidence of Kaposi's sarcoma (10%), and the high mortality rate (34% died during initial hospitalization, 74% after one year of follow-up). Tuberculosis occurred in 10% of cases, preceding other opportunistic infections by four to 24 months. We found that AIDS was a common disease among inpatient IVDAs, and in one of the participating hospitals, its incidence was similar to that of infective endocarditis. Acquired immunodeficiency syndrome should be considered as the underlying illness in all IVDAs with oral thrush, shortness of breath, pneumonia, or extra-pulmonary tuberculosis.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D000328:Adult; D000906:Antibodies / Q000032:analysis; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral / Q000032:analysis; D001927:Brain Diseases / Q000150:complications; D002177:Candidiasis / Q000150:complications; D003453:Cryptococcosis / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous / Q000009:adverse effects; D008297:Male; D009519:New York City; D011020:Pneumonia, Pneumocystis / Q000150:complications; D012190:Retroviridae / Q000276:immunology; D012306:Risk; D012959:Socioeconomic Factors; D019966:Substance-Related Disorders; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000150:complications; D014376:Tuberculosis / Q000150:complications; D014505:Urban Population
D000906:Antibodies; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral