[Study and characterization of lipid factors that inhibit cellular proliferation in MCG3 rat T lymphoma].
Lipid factors that inhibit cellular proliferation have been detected in MCG3 cells, a T lymphoma of B10 mouse. The inhibiting effect is cytostatic, non cytotoxic, reversible and lacks species and tissue-specificity. These lipids have been isolated by Thin Layer Chromatography (chloroform:methanol:water, 60:38:8) showing an Rf100 between 36 and 42, similar to that shown by gangliosides and phosphatidylinositol.
D000818:Animals; D002455:Cell Division / Q000187:drug effects*; D002855:Chromatography, Thin Layer; D008223:Lymphoma / Q000473:pathology*; D051379:Mice; D013601:T-Lymphocytes
Estudio y caracterización de factores lipídicos inhibidores de la proliferación celular (FLIPC) en el linfoma T de ratón MCG3.