Human alloantiserum against PHA-activated cells. Cytotoxicity associated with the HLA-A3 antigen.
Sera from transfused patients frequently show reactivity against polymorphic determinants expressed on PHA-activated but not resting mononuclear cells. One of these sera shows cytotoxicity associated with the HLA-A3 antigen.
D000920:Antibody-Dependent Cell Cytotoxicity; D003165:Complement System Proteins / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology*; D015791:HLA-A3 Antigen; D006801:Humans; D066298:In Vitro Techniques; D007518:Isoantibodies / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology; D010835:Phytohemagglutinins / Q000494:pharmacology
D006680:HLA Antigens; D015791:HLA-A3 Antigen; D007518:Isoantibodies; D010835:Phytohemagglutinins; D003165:Complement System Proteins