title: Study of rosin glycerol esters as microencapsulating materials.
abstract: Rosin esters were prepared by heating rosin with glycerol and intermediate reaction products with different acid values were withdrawn. Salicylic acid granules were encapsulated using a 10 per cent solution of rosin esters in acetone. The coated microcapsules were evaluated for moisture absorption, flow properties and dissolution studies. The results showed that rosin and rosin-glycerol intermediates with acid values of 122, 105 and 55 had excellent moisture protection properties. Dissolution studies showed that these could be used for delayed release of drug.
mesh_terms: D004339:Drug Compounding / Q000379:methods*; D005990:Glycerol; D012116:Resins, Plant; D012459:Salicylates / Q000008:administration & dosage; D020156:Salicylic Acid; D012995:Solubility
chemical_list: D012116:Resins, Plant; D012459:Salicylates; C013893:rosin; D020156:Salicylic Acid; D005990:Glycerol