title: Human maternal and fetal response to graded exercise.
abstract: Six healthy active women in the third trimester of pregnancy participated in a graded exercise protocol to levels of exertion perceived to be equivalent to that of their usual exercise regimen. Fetal heart rate response (FHR) was documented by ultrasound transducer and confirmed (n = 1) by ultrasonic visualization. Resting maternal O2 consumption was 277 +/- 50 (SD) ml/min and rose to 1,132 +/- 202 ml/min at a mean final exercise intensity of 79 +/- 9 W after 12.8 +/- 1.7 min on a cycle ergometer. There was no significant change in maternal serum insulin, growth hormone, glucose, or pH values. Maternal leukocyte count, hemoglobin, and venous lactate levels rose significantly during the exercise (P less than 0.05). FHR prior to exercise was 142 +/- 4 beats/min and decreased to 84 +/- 34 beats/min during exercise. The decrease in FHR was documented within 1 min of initiating exercise in all cases. During exercise, fetal movements were not accompanied by FHR accelerations. Within 1 min following the cessation of exercise, FHR rose to 143 +/- 8 beats/min and fetal movements were accompanied by FHR accelerations. Since the recovery of FHR occurred immediately after cessation of maternal exercise, this level of maternal exercise does not appear to be harmful to the fetus.
mesh_terms: D005080:Exercise Test; D005260:Female; D005318:Fetal Heart / Q000502:physiology*; D005323:Fetal Monitoring; D005324:Fetal Movement; D006339:Heart Rate; D006400:Hematocrit; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D007958:Leukocyte Count; D008431:Maternal-Fetal Exchange; D010101:Oxygen Consumption; D005082:Physical Exertion; D011247:Pregnancy; D014463:Ultrasonography
chemical_list: D007773:Lactates; D019344:Lactic Acid