title: A 1949 outbreak of Pontiac fever-like illness in steam condenser cleaners.
abstract: A 1949 outbreak of flu-like illness in steam-turbine condenser cleaners was investigated in 1979. Clinical and epidemiologic features matched those in previously described outbreaks of nonpneumonic legionellosis (Pontiac fever). Titers by indirect immunofluorescence using polyvalent Legionella pneumophila antigen were significantly higher for late convalescent-phase serum samples from condenser workers than for control serum samples submitted to the Centers for Disease Control. Three workers who had cleaned the condensers on several occasions had experienced recurrent illness associated with these operations, which might support the theory that nonpneumonic legionellosis is caused by an immune reaction to an inhaled antigen or bacterial toxin of L. pneumophila, rather than a true infection.
mesh_terms: D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis; D004196:Disease Outbreaks / Q000453:epidemiology*; D005334:Fever / Q000453:epidemiology* / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006801:Humans; D007875:Legionella / Q000276:immunology; D008297:Male; D009784:Occupational Diseases / Q000453:epidemiology* / Q000276:immunology; D011210:Power Plants; D014768:Virginia
chemical_list: D000907:Antibodies, Bacterial