title: Antidepressant effects of light in seasonal affective disorder.
abstract: The authors treated winter depression in 13 patients with typical seasonal affective disorder by extending the length of winter days with bright and dim light in the morning and evening in a balanced-order crossover study. Bright light had a marked antidepressant effect, whereas the dim light did not. This response could not be attributed to sleep deprivation. Subsequent pilot studies indicated that bright evening light alone is probably also effective. Several patients were able to maintain the antidepressant response throughout the winter months by continuing daily light treatments.
mesh_terms: D000328:Adult; D000553:Ambulatory Care; D001714:Bipolar Disorder / Q000523:psychology / Q000628:therapy; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008027:Light; D008297:Male; D010789:Phototherapy; D011569:Psychiatric Status Rating Scales; D012621:Seasons; D012890:Sleep; D014851:Wakefulness