title: Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain.
abstract: The rate of tryptophan hydroxylation in vivo is unaltered in brain areas of 5, 9 and 21 week-old Lyon genetically Hypertensive (LH) rats as compared to both Lyon Normotensive (LN) and Low Blood Pressure (LL) rats, except for a decrease in the C1 area of the medulla oblongata in 9 week-old animals.
mesh_terms: D006916:5-Hydroxytryptophan / Q000378:metabolism; D000375:Aging; D000818:Animals; D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D001921:Brain / Q000378:metabolism*; D006834:Hydrazines / Q000494:pharmacology; D006900:Hydroxylation; D006973:Hypertension / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism; D008526:Medulla Oblongata / Q000378:metabolism; D011903:Raphe Nuclei / Q000378:metabolism; D051381:Rats; D011922:Rats, Mutant Strains; D014364:Tryptophan / Q000378:metabolism*
chemical_list: D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D006834:Hydrazines; D014364:Tryptophan; C004297:3-hydroxybenzylhydrazine; D006916:5-Hydroxytryptophan