Influence of the genetic background on cell division and cell lysis: behaviour of different Escherichia coli strains carrying the ts-52 or the ftsA-3 mutation.
The analysis of Escherichia coli strains harbouring division mutations, namely the ts-52 or the ftsA-3 division alleles, in different genetic backgrounds showed that treatment with chloramphenicol in cells incubated at the restrictive temperature induced either cell lysis (ts-52 and ftsA-3 in MC-6 genetic background) or cell division (ts-52 in OV-2 genetic background). This chloramphenicol treatment of ftsA-3 filaments (previously designated at divA) does not induce cell division but does induce cell lysis.
D000483:Alleles; D002455:Cell Division; D002701:Chloramphenicol / Q000494:pharmacology*; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects / Q000235:genetics*; D005838:Genotype; D007700:Kinetics; D009154:Mutation; D013045:Species Specificity
D002701:Chloramphenicol