title: Monoclonal antibody studies in the skin lesions of patients with anetoderma.
abstract: In all five patients studied, monoclonal antibody studies of cryostat sections of skin biopsy specimens of anetoderma lesions revealed inflammatory cells reacting with anti-Leu-1, pan-T-cell antibody, and anti-Leu-3a, the helper/inducer T-cell antibody. Small numbers of suppressor cells were present in only three biopsy specimens. Four specimens showed OKM1, antibody-reacting cells (monocytes). The age of the lesion was not correlated with inflammation or the T-cell subsets identified.
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D001284:Atrophy / Q000473:pathology; D003872:Dermatitis / Q000473:pathology; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000276:immunology; D006651:Histocytochemistry; D006801:Humans; D007120:Immunochemistry; D008875:Middle Aged; D012871:Skin Diseases / Q000276:immunology / Q000473:pathology*; D013601:T-Lymphocytes / Q000145:classification*
chemical_list: D000911:Antibodies, Monoclonal; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II