Allergic bronchopulmonary aspergillosis.
Allergic bronchopulmonary aspergillosis (ABPA) occurs as a complication of asthma. It presents as an infiltrative pulmonary disorder with respiratory and systemic symptoms, eosinophilia, elevated total serum IgE, and skin sensitizing, as well as precipitating antibodies to Aspergillus fumigatus. Sputum cultures are not always positive for the organism. If unchecked, the disease may lead to bronchiectasis and ultimately pulmonary fibrosis. Therapy consists mainly of corticosteroids.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D001232:Aspergillus fumigatus / Q000276:immunology; D001249:Asthma / Q000150:complications*; D001985:Bronchial Provocation Tests; D006801:Humans; D008168:Lung / Q000473:pathology; D013902:Radiography, Thoracic
D000305:Adrenal Cortex Hormones