title: Vasculogenic impotence evaluated by high-resolution ultrasonography and pulsed Doppler spectrum analysis.
abstract: Vasculogenic impotence was evaluated by high-resolution sonography and quantitative Doppler spectrum analysis in 21 patients and two normal volunteers. Erection was induced by intracorporeal injection of papaverine, and B-scan imaging and Doppler analysis were performed with the penis flaccid and erect. The corpora cavernosa and its deep arteries, median septum, and corpus spongiosum were clearly displayed in every subject, with the dorsal vein and dorsal artery seen ventral to the corpora cavernosa. In the flaccid state, in all subjects, Doppler analysis demonstrated flow in the dorsal arteries but not in the deep arteries. During erection, the B-mode image showed varying degrees of enlargement of the corpora cavernosa, with increased tissue echogenicity, as well as a hypoechoic area in the peri-arterial region. The diameter of the penile arteries and flow within them also increased by varying degrees. Quantification of blood flow through all deep and dorsal arteries is feasible with this technique.
mesh_terms: D000328:Adult; D000368:Aged; D001158:Arteries / Q000473:pathology; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000494:pharmacology; D010413:Penis / Q000098:blood supply* / Q000473:pathology; D012039:Regional Blood Flow / Q000187:drug effects; D014463:Ultrasonography
chemical_list: D010208:Papaverine