Co-existence of cholecystokinin- or gastrin-like peptides with other peptides in the hypophysis and the hypothalamus.
The presence of cholecystokinin and gastrin has been reported in the hypothalamohypophyseal system. These peptides present a peculiar distribution in the hypothalamic nuclei, the median eminence, and the neurohypophysis. CCK and gastrin have close relationships with other peptides like oxytocin, CRF, vasopressin, and the enkephalins; these relationships vary in different projecting areas and in different types of hypothalamic neurons. The functional role of G-CCK in neurosecretion seems to be linked to the role of these closely associated peptides and certainly deserves further investigation.
D000818:Animals; D002766:Cholecystokinin / Q000032:analysis* / Q000276:immunology; D003346:Corticotropin-Releasing Hormone / Q000032:analysis; D005755:Gastrins / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000032:analysis; D007031:Hypothalamus / Q000032:analysis*; D009419:Nerve Tissue Proteins / Q000032:analysis*; D010902:Pituitary Gland / Q000032:analysis*
D005755:Gastrins; D009419:Nerve Tissue Proteins; D002766:Cholecystokinin; D003346:Corticotropin-Releasing Hormone