title: [Current status of therapy of liver metastases of colorectal carcinoma].
abstract: Surgical removal of liver metastases stemming from colo-rectal carcinoma is the therapy of choice of this disease. Postoperative mortality is 8%, 5 years survival rate ranges between 22 and 52% and can be considered to be good. However in 85% of patients surgery is not possible because of widespread involvement of the liver. Systemic chemotherapy yields remission rates up to 23% without increase of survival time, and therefore is no real alternative. Infusion of cytostatic drug into the hepatic artery yields better results, e.g. remission rates up to 85% and average survival times up to 26 months.
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D003110:Colonic Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003250:Constriction; D006499:Hepatic Artery; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D012004:Rectal Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Aktueller Stand der Therapie von Lebermetastasen kolorektaler Karzinome.