Bipolar affective symptoms associated with use of captopril and abrupt withdrawal of pargyline and propranolol.
A woman with a family history but no personal history of depression developed bipolar symptoms associated with manipulations of her antihypertensive regimen. The author discusses hypotheses regarding the effects of these manipulations and the implications for treatment.
D001714:Bipolar Disorder / Q000139:chemically induced / Q000188:drug therapy / Q000209:etiology*; D002216:Captopril / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D008875:Middle Aged; D009661:Nortriptyline / Q000627:therapeutic use; D010293:Pargyline / Q000009:adverse effects*; D011392:Proline / Q000031:analogs & derivatives*; D011433:Propranolol / Q000009:adverse effects*; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
D011392:Proline; D002216:Captopril; D010293:Pargyline; D011433:Propranolol; D009661:Nortriptyline