Pathogenesis and treatment of recurrent erosion.
A series of recurrent corneal erosions secondary to map-dot-fingerprint dystrophy is presented. Erosions were closely related to the Hudson-Stahli line, and this may be a factor in pathogenesis. Traumatic abrasions did not demonstrate such localisation, evidence that trauma is not a primary cause. A trial of management with therapeutic contact lenses versus topical medication was performed. Therapeutic contact lenses were shown to be inferior and had a high complication rate. Recurrent erosion is often considered an indication for therapeutic contact lenses, but this is questioned and great caution recommended in such use.
D000287:Administration, Topical; D000328:Adult; D002482:Cellulose / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D003261:Contact Lenses; D003317:Corneal Dystrophies, Hereditary / Q000150:complications; D003320:Corneal Ulcer / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy; D004338:Drug Combinations / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D065347:Hypromellose Derivatives; D008297:Male; D008747:Methylcellulose / Q000031:analogs & derivatives*; D008875:Middle Aged; D012008:Recurrence
D004338:Drug Combinations; D065347:Hypromellose Derivatives; D002482:Cellulose; D008747:Methylcellulose