[Association of antigens of the histocompatibility system in A and B loci in systemic lupus erythematosus].
The typing of histocompatibility HLA-B and A antigens was made in 63 patients with systemic lupus erythematosus (SLE). It was shown that the carriership of some histocompatibility antigens and association of definite antigens, in particular, increases the relative risk of the development of SLE. This was especially applicable to the following gene combinations: HLA-B-8/B12, HLA-B-18/10, HIA-AII/AI/A3 and some others. Definite associations were revealed between carriership of some histocompatibility antigens and development of some manifestations of SLE.
D004198:Disease Susceptibility; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006238:Haploidy; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000235:genetics / Q000276:immunology*; D010641:Phenotype; D012306:Risk
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens
Izuchenie sochetaniia antigenov sistemy gistosovmestimosti v lokusakh A i B pri sistemnoĭ krasnoĭ volchanke.