The relationship between 17 beta hydroxysteroid dehydrogenase and breast tumour site and size.
The activity of 17 beta hydroxysteroid dehydrogenase (170HSD) was measured in adipose tissue adjacent to benign or malignant breast tumours. 170HSD activity was significantly correlated with tumour size in malignant tumours (r = 0.75) but not with benign tumours (r = 0.28). Enzyme activity was reduced in adipose tissue adjacent to tumours obtained from inferior breast quadrants.
D015067:17-Hydroxysteroid Dehydrogenases / Q000032:analysis*; D000273:Adipose Tissue / Q000201:enzymology; D000328:Adult; D000368:Aged; D001835:Body Weight; D001943:Breast Neoplasms / Q000201:enzymology* / Q000473:pathology; D004958:Estradiol / Q000378:metabolism; D004970:Estrone / Q000378:metabolism; D005260:Female; D006801:Humans; D008875:Middle Aged
D004970:Estrone; D004958:Estradiol; D015067:17-Hydroxysteroid Dehydrogenases