Effects of sub-bactericidal concentrations of antibiotics in experimental models of endocarditis.
Subinhibitory and sub-bactericidal concentrations of antibiotics significantly influence host-bacterial interactions. This paper reviews the pathogenesis of endocarditis and examines how subinhibitory concentrations of antibiotics may influence the course of the disease. At present significant effects have been documented only for the stage of bacterial adherence to the damaged valve.
D000268:Adhesiveness; D000818:Animals; D000900:Anti-Bacterial Agents / Q000378:metabolism* / Q000627:therapeutic use; D001419:Bacteria / Q000472:pathogenicity; D004195:Disease Models, Animal; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000378:metabolism* / Q000382:microbiology
D000900:Anti-Bacterial Agents