title: Dose response studies with propofol ('Diprivan') in unpremedicated patients.
abstract: In younger patients, 2.25 mg/kg is a reliable induction dose of propofol, whereas this level falls to 1.5 mg/kg in older patients. The incidence of hypotension and apnoea is dose-dependent in all patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000771:Anesthesia, Intravenous; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010636:Phenols / Q000008:administration & dosage / Q000009:adverse effects; D015742:Propofol
chemical_list: D010636:Phenols; D015742:Propofol