[Histone antibodies: significance in the diagnosis of SLE in comparison to dsDNA antibodies and antibodies to extractable nuclear antigens].
Antibodies to histones of the IgG-class are specific for SLE and can be shown in 23% of the sera. They are not associated with clinical symptoms of SLE, but with dsDNA-antibodies.
D000974:Antibodies, Antinuclear / Q000032:analysis*; D034961:Antigens, Nuclear; D004247:DNA / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006657:Histones / Q000276:immunology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000276:immunology; D009698:Nucleoproteins / Q000276:immunology*
D000974:Antibodies, Antinuclear; D034961:Antigens, Nuclear; D006657:Histones; D009698:Nucleoproteins; C026904:deoxyribonucleoprotein antibodies; D004247:DNA
Histonantikörper: Bedeutung in der Diagnostik des SLE im Vergleich zu dsDNS-Antikörpern und Antikörpern gegen "extrahierbare nukleäre Antigene".