[Comparative ultrastructural-morphometric studies of the human myocardium before and following heart surgery using myocardial protection].
Ultrastructural morphometric changes of the myocardium were reported after biopsy during the aortic occlusion time and during the reperfusion time throughout cardiosurgery in two groups of patients: Group AKB (aorto-coronary bypass): The mitochondria are increasing in the number and are decreasing in the size. The signs of biogenesis are shown. The condition after reperfusion is good. Group AVR (aortic valve replacement): The mitochondria are decreasing in the number and increasing in the size. These are signs of swelling and/or fusion. The condition after reperfusion is not so good. Therefore patients with AVR are a higher risk for cardiosurgery than the patients with chronic ischemic heart disease (AKB).
D000328:Adult; D001021:Aortic Valve / Q000601:surgery*; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D006324:Heart Arrest, Induced; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D008929:Mitochondria, Heart / Q000648:ultrastructure; D009206:Myocardium / Q000473:pathology*; D010477:Perfusion; D011183:Postoperative Complications / Q000473:pathology
Vergleichende ultrastrukturell-morphometrische Untersuchungen am menschlichen Herzmuskel vor und nach herzchirurgischen Eingriffen unter Myokardprotektion.