Circadian adrenocortical periodicity changes in adult rats stimulated during early development--II. Effect of cold stress.
Rats were cooled at different time points of early postnatal development to study the effects of short-term stress on the parameters of the circadian rhythm of the adrenocortical function in adults. It was found that rats stressed at the age of 2-4 or 17-19 days exhibit modified timing in the circadian periodicity of the adrenocortical function as adults. Cold stimulation during early development does not affect the function of isolated adrenal glands in vitro. It is concluded that the effect of early stress on the adrenocortical rhythmicity in adults is mediated through central regulatory mechanisms. This effect depends on the age when the rat pups are exposed to cold stress.
D000305:Adrenal Cortex Hormones / Q000097:blood; D000311:Adrenal Glands / Q000254:growth & development / Q000378:metabolism / Q000503:physiopathology*; D000367:Age Factors; D000818:Animals; D002940:Circadian Rhythm; D003080:Cold Temperature; D066298:In Vitro Techniques; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000378:metabolism* / Q000503:physiopathology
D000305:Adrenal Cortex Hormones