Plasticity of vasopressin- and oxytocin-containing fibers in the median eminence in hypophysectomized young and old mice.
Rearrangements of vasopressin- and oxytocin-containing fibers in the external layer of the median eminence after hypophysectomy were compared between young and old mice. In 3-month-old hypophysectomized mice, the increase in the number of fibers containing vasopressin was greater than that observed in 19-month-old hypophysectomized ones, suggesting a decrease in axonal plasticity in old mice. No difference with age was detected for the plasticity of fibers containing oxytocin.
D000367:Age Factors; D000818:Animals; D001369:Axons / Q000502:physiology; D005260:Female; D007016:Hypophysectomy; D007124:Immunoenzyme Techniques; D008473:Median Eminence / Q000378:metabolism*; D051379:Mice; D008810:Mice, Inbred C57BL; D009473:Neuronal Plasticity; D010121:Oxytocin / Q000378:metabolism*; D014667:Vasopressins / Q000378:metabolism*
D014667:Vasopressins; D010121:Oxytocin