title: [External respiratory function in patients with primary pulmonary emphysema etiologically related to alpha 1-antitrypsin deficiency].
abstract: To improve the diagnosis of primary lung emphysema etiologically linked with alpha-trypsin deficiency, the authors provide the results of a detailed clinico-functional study of 6 patients with an appreciable deficiency of this enzyme. According to the clinical and functional signs, all the patients were diagnosed to have a typical, pronounced lung emphysema. Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
mesh_terms: D000328:Adult; D001991:Bronchitis / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D011659:Pulmonary Gas Exchange; D012119:Respiration; D012129:Respiratory Function Tests; D019896:alpha 1-Antitrypsin Deficiency
vernacular_title: Funktsiia vneshnego dykhaniia u bol'nykh pervichnoĭ émfizemoĭ legkikh, étiologicheski sviazannoĭ s defitsitom al'fa 1-antitripsina.