Antiepithelial autoantibodies associated with the feline eosinophilic granuloma complex.
A retrospective study of banked sera from 19 cats with the eosinophilic granuloma complex revealed that 68% of affected cats had circulating antibodies to components of normal cat epithelium. Seemingly, the eosinophilic granuloma complex of cats may be an autoimmune disease; however, epidermal damage caused by the eosinophilic granuloma complex may release altered self-antigens to which the cat's immune system responds.
D000818:Animals; D001323:Autoantibodies / Q000032:analysis*; D002371:Cat Diseases / Q000276:immunology*; D002415:Cats; D004803:Eosinophilic Granuloma / Q000662:veterinary*; D004848:Epithelium / Q000276:immunology; D005455:Fluorescent Antibody Technique
D001323:Autoantibodies