[Regulating effect of bone marrow cells on human T-lymphocyte function].
A study was made of the regulatory effect of human bone marrow cells in two experimental systems: lymphocyte proliferation in response to PHA, and spontaneous and PHA-induced production of macrophage migration inhibition factor (MIF) by peripheral blood lymphocytes. It was shown that bone marrow cells inhibit the proliferative activity of stimulated peripheral blood lymphocytes and induced MIF production. The effect of bone marrow cells on spontaneous MIF production was found to be inconclusive.
D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D006801:Humans; D008263:Macrophage Migration-Inhibitory Factors / Q000096:biosynthesis; D010835:Phytohemagglutinins / Q000494:pharmacology; D013103:Spherocytosis, Hereditary / Q000276:immunology; D013601:T-Lymphocytes / Q000166:cytology* / Q000187:drug effects
D008263:Macrophage Migration-Inhibitory Factors; D010835:Phytohemagglutinins
Reguliruiushchee vliianie kletok kostnogo mozga na funktsiiu T-limfotsitov cheloveka.