The limitations of ultrasonography in the antenatal diagnosis of congenital cerebral malformations.
Ultrasonography is widely used in the antenatal diagnosis of neural tube defects. A case of holoprosencephaly associated with trisomy 18 is presented to illustrate the limitations of ultrasonography in making antenatal diagnosis of cerebral malformations. The use of a better organ-imaging technique, such as nuclear magnetic resonance, is suggested.
D000015:Abnormalities, Multiple; D000328:Adult; D001921:Brain / Q000002:abnormalities*; D002902:Chromosomes, Human, 16-18; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014314:Trisomy; D014463:Ultrasonography