title: Modification of plasma cholesterol through exercise. Rationale and recommendations.
abstract: Until relatively recently, clinical information regarding plasma lipoproteins and their association with human atherosclerosis had been based on epidemiologic evidence obtained from cross-sectional studies or prospective studies that used clinical events as end points. Authorities have cautioned against the interpretation of these results to imply that drug therapy be used to alter the high-density lipoprotein (HDL) fraction of total cholesterol. Several recent investigations strongly suggest that decreasing the low-density lipoprotein fraction of total cholesterol and increasing the HDL fraction may alter the progression of atherosclerosis. Appropriate exercise may be a viable tool to assist in elevating plasma HDL levels.
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D001161:Arteriosclerosis / Q000097:blood / Q000517:prevention & control*; D001835:Body Weight; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D005081:Exercise Therapy; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D012737:Sex Factors
chemical_list: D008076:Cholesterol, HDL; D008055:Lipids; D002784:Cholesterol