Neonatal hypertension from a unilateral multicystic dysplastic kidney.
Multicystic renal dysplasia is an extremely uncommon cause of hypertension in children and the few reported cases have not been of newborns. We report on a neonate in whom severe hypertension associated with elevated peripheral plasma renin resulted from a unilateral multicystic dysplastic kidney. Hypertension and plasma renin activity normalized after unilateral nephrectomy. No evidence of perfusion or excretory renal function in the dysplastic kidney was present on a radionuclide renal scan. This child demonstrates a relationship between hypertension and unilateral multicystic renal dysplasia.
D001794:Blood Pressure; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000151:congenital* / Q000601:surgery; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities*; D052177:Kidney Diseases, Cystic / Q000151:congenital* / Q000601:surgery; D009392:Nephrectomy; D012083:Renin / Q000097:blood
D012083:Renin