[Mechanisms in the regulation of the level of lipid radiosensitizing agents in yeast cells with different types of radioresistance].
Factors controlling the lipid sensitizers level: the composition of fatty lipid acids, their antioxidative activity, the enzyme systems reactivity (superoxide dismutase, catalase, glutatione peroxidase and glutatione reductase) have been studied in yeast cells with different radioresistance. In six lines of yeast cells the leading role of superoxide dismutase--one of the regulators of lipid peroxidation have been demonstrated in cells native radioresistance formation.
D002374:Catalase / Q000528:radiation effects; D005227:Fatty Acids / Q000528:radiation effects; D005979:Glutathione Peroxidase / Q000528:radiation effects; D005980:Glutathione Reductase / Q000528:radiation effects; D008055:Lipids / Q000528:radiation effects*; D010843:Pichia; D011836:Radiation Tolerance; D011838:Radiation-Sensitizing Agents / Q000528:radiation effects*; D012441:Saccharomyces cerevisiae; D013482:Superoxide Dismutase / Q000528:radiation effects; D015003:Yeasts / Q000201:enzymology / Q000528:radiation effects*
D005227:Fatty Acids; D008055:Lipids; D011838:Radiation-Sensitizing Agents; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D005980:Glutathione Reductase
Mekhanizmy reguliatsii urovnia lipidnykh radiosensibilizatorov v kletkakh drozhzheĭ s razlichnoĭ radiorezistenost'iu.