Cultured epithelium as a skin substitute.
The history of techniques for the replacement of lost skin is reviewed, including the current research in the use of synthetic dermal substitutes, skin allografts and immunosuppression, and tissue-cultured epithelial autografts. Developments in each of these three areas are encouraging steps toward the development of a skin substitute that would be immediately available for coverage of even massive areas of skin loss.
D001187:Artificial Organs; D002056:Burns / Q000601:surgery; D002478:Cells, Cultured; D002648:Child; D002675:Child, Preschool; D004848:Epithelium; D005260:Female; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D008567:Membranes, Artificial; D012867:Skin / Q000293:injuries*; D016038:Skin Transplantation; D013518:Surgery, Plastic; D014182:Transplantation, Autologous; D014945:Wound Healing
D008567:Membranes, Artificial