title: Tracheal repair with fibrin glue.
abstract: This animal study evaluated Fibrin Sealant, a multicomponent biologic adhesive, in tracheal operations. We conclude that the use of Fibrin Sealant in tracheal reconstruction results in a stable, leakless trachea, has good systemic and local compatibility, promotes tracheal wound healing, and reduces significantly the number of sutures required for end-to-end anastomosis.
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D004285:Dogs; D004338:Drug Combinations / Q000627:therapeutic use; D005176:Factor XIII / Q000627:therapeutic use*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000627:therapeutic use*; D005353:Fibronectins / Q000627:therapeutic use*; D013917:Thrombin / Q000627:therapeutic use*; D014132:Trachea / Q000166:cytology / Q000601:surgery*; D014945:Wound Healing / Q000187:drug effects
chemical_list: D001672:Biocompatible Materials; D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D005353:Fibronectins; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin