Testing for mutagens in an aluminium plant. The results of Salmonella typhimurium tests on expectorates from exposed workers.
Methanol extracts of hydrolyzed expectorate samples from workers in a Söderberg potroom were evaluated by the Salmonella reversion assay. The expectorates from exposed workers--mostly from smokers, but also to a certain extent from nonsmokers--were mutagenic; however, the control samples from both smokers and nonsmokers were not. The positive results produced by the expectorate samples from the exposed smokers suggest a synergistic relationship between exposure to air pollution of the working atmosphere and smoking.
D000535:Aluminum / Q000009:adverse effects*; D006801:Humans; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis*; D009784:Occupational Diseases / Q000175:diagnosis*; D012486:Salmonella typhimurium / Q000187:drug effects; D012907:Smoking; D013183:Sputum / Q000032:analysis
D009153:Mutagens; D000535:Aluminum