title: Immunology of corneal allograft rejection: HLA-DR antigens on human corneal cells.
abstract: Human stromal and endothelial cultures were established from corneas obtained from the Maryland Eye Bank. Cultures were incubated in the presence of human gamma interferon for 4 days, trypsinized, washed, and then stained with a monoclonal reagent specific for human Class II (HLA-DR) antigens. Under these conditions, 100% of human corneal endothelial cells and 40 to 70% human corneal stromal cells expressed HLA-DR antigens.
mesh_terms: D003315:Cornea / Q000276:immunology; D003319:Corneal Stroma / Q000276:immunology; D016039:Corneal Transplantation; D046508:Culture Techniques; D004727:Endothelium / Q000276:immunology; D006084:Graft Rejection; D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D006801:Humans; D014181:Transplantation Immunology
chemical_list: D006684:HLA-DR Antigens; D000949:Histocompatibility Antigens Class II