[Hybridomas producing monoclonal antibodies to influenza viruses].
Six hybrid clones producing monoclonal antibodies (MCA) to influenza A/FMI/47 virus and 9 hybrid clones producing MCA to influenza A/USSR/090/77 virus have been developed. The resulting MCA have been shown to be highly specific for influenza viruses of H1N1 serotype and differentiating H1N1 viruses from H0N1 and H3N2. In 3 out of 11 hybrid clones under study, unique marker chromosomes not occurring in cells of the myeloma parents have been found.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000096:biosynthesis*; D000914:Antibodies, Viral / Q000032:analysis / Q000096:biosynthesis*; D005455:Fluorescent Antibody Technique; D006385:Hemagglutination Inhibition Tests; D006825:Hybridomas / Q000276:immunology*; D009980:Influenza A virus / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral
Izuchenie gibridom, produtsiruiushchikh monoklonal'nye antitela k virusam grippa.