Transfer of the virulence plasmid of Yersinia pestis to Yersinia pseudotuberculosis.
Transposon Tn5 insertion derivatives of the virulence plasmid pYV019 of Yersinia pestis were transferred by P1 transduction into a plasmid-free strain of Y. pseudotuberculosis. One of these plasmid derivatives conferred virulence upon the Y. pseudotuberculosis strain. This strain had the ability to express temperature-inducible plasmid-coded outer membrane proteins and was also found to be Ca2+ dependent.
D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000032:analysis; D002118:Calcium / Q000494:pharmacology; D051379:Mice; D010957:Plasmids; D014161:Transduction, Genetic; D014774:Virulence; D015007:Yersinia / Q000235:genetics* / Q000472:pathogenicity; D015010:Yersinia pestis / Q000235:genetics*; D015012:Yersinia pseudotuberculosis Infections / Q000382:microbiology
D001425:Bacterial Outer Membrane Proteins; D002118:Calcium