Cellulose-walled microcapsules: 1. The effect of the solvent-non solvent proportions on the preparation of microcapsules from the system ethyl cellulose-chloroform-ethane diol.
The phase diagram of the system ethyl cellulose-chloroform-ethane diol has been studied and the differing phase regions determined. The effect of temperature of these regions is recorded. The phase diagram is used to determine the optimal conditions for the preparation of microcapsules with a phenobarbitone core and the size distribution of the microcapsules is recorded.
D002482:Cellulose / Q000031:analogs & derivatives; D002725:Chloroform; D004339:Drug Compounding; D000431:Ethanol; D013696:Temperature; D014783:Viscosity
D000431:Ethanol; D002725:Chloroform; C013517:ethyl cellulose; D002482:Cellulose