title: The effect of daily application of a neutral 0.25% F- mouth-rinse on mineral loss in surface layers of enamel under intra oral cariogenicity tests conditions.
abstract: The effects of daily use of a 0.025% F- mouth-rinse on microhardness and mineral loss in the enamel lesion has been studied under Intra Oral Cariogenicity Test (ICT) conditions. The penetration depth was changed from 16 to 9 microns by F-. Moreover, the inhibition was found fairly constantly distributed over the whole lesion for the Ca and P loss without any CaF2 formation. In this way the effectiveness of the 0.025% F- mouth-rinse program can be explained.
mesh_terms: D000818:Animals; D002118:Calcium / Q000032:analysis; D002326:Cariogenic Agents / Q000494:pharmacology*; D002417:Cattle; D003743:Dental Enamel / Q000032:analysis / Q000187:drug effects*; D003747:Dental Enamel Solubility; D005459:Fluorides / Q000008:administration & dosage* / Q000494:pharmacology; D006244:Hardness; D006801:Humans; D008903:Minerals / Q000032:analysis*; D009067:Mouthwashes; D010758:Phosphorus / Q000032:analysis
chemical_list: D002326:Cariogenic Agents; D008903:Minerals; D009067:Mouthwashes; D010758:Phosphorus; D005459:Fluorides; D002118:Calcium