Ischemic lesions of the occipital cortex and optic radiations: positron emission tomography.
We used 18-F-fluoro-2-deoxyglucose positron emission tomography (PET) and computed tomography (CT) to study eight patients with homonymous hemianopias or quadrantanopias due to ischemic lesions of the visual pathways. Four patients with ischemic damage to all or part of the occipital lobe had decreased glucose metabolism in the affected region. Three patients with ischemic damage limited to the optic radiations had decreased glucose metabolism in the portion of striate cortex appropriate for the visual field defect. Changes in glucose metabolism frequently occurred in the undamaged ipsilateral thalamus and visual association areas.
D000328:Adult; D000368:Aged; D003847:Deoxyglucose / Q000031:analogs & derivatives; D005260:Female; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism; D006801:Humans; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000000981:diagnostic imaging* / Q000378:metabolism; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000000981:diagnostic imaging / Q000378:metabolism; D014793:Visual Cortex / Q000000981:diagnostic imaging / Q000378:metabolism; D014795:Visual Pathways / Q000000981:diagnostic imaging* / Q000378:metabolism
D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D005947:Glucose