title: Killing of Escherichia coli by human polymorphonuclear leucocytes in the presence of Bacteroides fragilis.
abstract: The inhibitory effect of Bacteroides fragilis on the in vitro killing of Escherichia coli by polymorphonuclear leucocytes was studied with two pairs of E coli and B fragilis isolated from human wound infections. Both B fragilis strains behaved similarly: they inhibited the killing of one E coli strain, while the killing of the other E coli strain was not affected. The different behaviour of the two E coli strains depended on their need for fresh serum in the killing by the polymorphonuclear leucocytes. The inhibitory effect of the B fragilis strains could be completely accounted for by their effect on complement.
mesh_terms: D001441:Bacteroides fragilis / Q000276:immunology*; D001770:Blood Bactericidal Activity; D003165:Complement System Proteins; D004926:Escherichia coli / Q000276:immunology*; D006801:Humans; D009504:Neutrophils / Q000276:immunology*; D013530:Surgical Wound Infection / Q000382:microbiology
chemical_list: D003165:Complement System Proteins