Demonstration of specific IgA in human feces after immunization with live Ty21a Salmonella typhi vaccine.
An enzyme-linked immunosorbent assay was applied to evaluate the appearance of specific IgA in fecal eluates of 11 normal subjects given oral live Salmonella typhi Ty21a vaccine. All subjects after immunization showed a detectable rise in levels of specific IgA to both lipopolysaccharide and flagellar antigens of S. typhi.
D000328:Adult; D000942:Antigens, Bacterial / Q000276:immunology; D001428:Bacterial Vaccines / Q000276:immunology*; D005243:Feces / Q000276:immunology*; D005260:Female; D005407:Flagella / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D007071:Immunoglobulin A, Secretory / Q000032:analysis / Q000096:biosynthesis*; D008070:Lipopolysaccharides / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012485:Salmonella typhi / Q000276:immunology*; D014611:Vaccination; D014613:Vaccines, Attenuated
D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D007071:Immunoglobulin A, Secretory; D008070:Lipopolysaccharides; D014613:Vaccines, Attenuated