Fibrin glue osteosynthesis of epiphyseal injuries.
Osteosynthesis of epiphyseal injuries by fibrin glue was tested in an experiment on ten dogs. In was successful in types II and III epiphyseal injuries (Salter and Harris) but failed in 50% of unstable type IV fractures. Plaster fixation of the extremity was necessary for the completion of osteosynthesis. Histology revealed uncomplicated bone healing. Clinical application of fibrin glue is to be expected primarily in the therapy of more stable type II and III epiphyseal injuries (Salter and Harris) with the fragments not exposed to major traction.
D000818:Animals; D004285:Dogs; D004338:Drug Combinations / Q000008:administration & dosage; D004838:Epiphyses / Q000293:injuries*; D005176:Factor XIII / Q000008:administration & dosage*; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen / Q000008:administration & dosage*; D005593:Fracture Fixation, Internal / Q000379:methods*; D011884:Radius / Q000601:surgery; D013917:Thrombin / Q000008:administration & dosage*; D014945:Wound Healing / Q000187:drug effects
D004338:Drug Combinations; D015718:Fibrin Tissue Adhesive; D005340:Fibrinogen; D005176:Factor XIII; D013917:Thrombin