title: Red blood cell membrane lipid peroxidation and chronic haemolysis in haemodialysis patients.
abstract: Pre dialysis concentrations of malonyldialdehyde (MDA) in the red blood cell membranes and pre and post dialysis percent variation of plasma haemoglobin levels are studied in a group of uraemic patients on maintenance haemodialysis both before and after a therapeutic trial with vitamin E. The findings show a significant correlation between MDA levels and percent variation of plasma haemoglobin during dialysis, thus indicating that reducing the amount of lipid peroxidation can help to reduce intradialytic chronic haemolysis.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008563:Membrane Lipids / Q000097:blood; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D014511:Uremia / Q000097:blood / Q000188:drug therapy / Q000628:therapy; D014810:Vitamin E / Q000494:pharmacology
chemical_list: D008054:Lipid Peroxides; D008563:Membrane Lipids; D014810:Vitamin E; D008315:Malondialdehyde