[Streptomyces spheroides M8-2 strain--a producer of extracellular proteolytic enzymes possessing fibrinolytic and thrombolytic action].
Strain Streptomyces spheroides M8-2 was obtained as a result of ultraviolet light action on the S. spheroides spores strain 35. The mutant is characterized by the considerable increase (in 4-5 times) of the extracellular proteolytic enzymes which are able to dissolve fibrin and thrombs. The description of the morfologic, cultural and physiologic-biochemical properties of the culture is given. The content of GC-pairs in DNK of the mutant and parent strains has been determined.
D000898:Antibiosis; D002364:Caseins / Q000378:metabolism; D005337:Fibrin / Q000378:metabolism; D005342:Fibrinolysis / Q000187:drug effects*; D066298:In Vitro Techniques; D009154:Mutation; D010447:Peptide Hydrolases / Q000096:biosynthesis* / Q000494:pharmacology / Q000528:radiation effects; D013302:Streptomyces / Q000166:cytology / Q000201:enzymology* / Q000528:radiation effects; D014466:Ultraviolet Rays
D002364:Caseins; D005337:Fibrin; D010447:Peptide Hydrolases
Shtamm Streptomyces spheroides M8-2--produtsent vnekletochnykh proteoliticheskikh fermentov, okazyvaiushchikh fibrinoliticheskoe i tromboliticheskoe deĭstvie.