Lymphocytes and Langerhans cells in the normal human cornea.
The distribution of B- and T-lymphocytes, of OKIa positive cells, and of HLA-ABC antigens in the normal cornea was investigated using monoclonal antibodies. The lymphocytes and Langerhans cells are present mainly in the well-vascularized limbic region but also occur albeit in small number in the center of the cornea. HLA-ABC antigens are strongly expressed on the epithelial cells of the cornea and the limbus.
D000368:Aged; D001402:B-Lymphocytes / Q000166:cytology; D003315:Cornea / Q000166:cytology* / Q000276:immunology; D003886:Descemet Membrane / Q000166:cytology; D004847:Epithelial Cells; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D000949:Histocompatibility Antigens Class II / Q000032:analysis*; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D007801:Langerhans Cells / Q000276:immunology*; D008214:Lymphocytes / Q000145:classification*; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000166:cytology
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D000949:Histocompatibility Antigens Class II