Healing and revascularization of apical periodontium and dental pulps in apicoectomized and nonapicoectomized tooth replants in monkeys. A study of fully developed teeth.
This report primarily concerns an experimental study of the effect of apicoectomy on the healing and revascularization of the periodontal membrane and dental pulps in tooth replants. Five rhesus monkeys (Macaca mulatta) were subjected to surgical procedures in which twenty incisor teeth were extracted and immediately replanted. Ten of these incisors were subjected to apicoectomy. Healing and revascularization of periapical tissues and dental pulps were evaluated by histologic and India-ink-perfusion techniques. Apicoectomized replants were characterized by (1) loss of dental substance (tooth apex) and creation of large periapical spaces, (2) exposure of dental pulps and production of periapical inflammatory processes with destruction of alveolar bone, and (3) blocking of normal healing because of persistence of chronic periapical inflammatory processes. In contrast, nonapicoectomized replants depicted short-lived primary inflammatory responses and healing processes characterized by variable histologic responses.
D000818:Animals; D001047:Apicoectomy; D003782:Dental Pulp / Q000098:blood supply* / Q000473:pathology; D007180:Incisor / Q000098:blood supply / Q000601:surgery*; D008253:Macaca mulatta; D010485:Periapical Periodontitis / Q000473:pathology; D010486:Periapical Tissue / Q000098:blood supply* / Q000473:pathology; D014090:Tooth Replantation; D014945:Wound Healing