[Pathology of the artificial esophagus made of skin].
Clinico-anatomical analysis of changes in the artificial oesophagi made of the skin and skin additions functioning in 13 patients during 10-38 years after the completion of the oesophagoplasty is given. Fistulas in the transplant wall connected with the effect of gastric juice are found in 4 patients. Constrictions of the transplants located anterothoracally due to the compression of the skin tube by the scars and the papilloma formation on its surface were revealed in 7 patients. Carcinoma of the skin addition developed in the presence of papillomatosis in 2 patients. Morphologically, a considerable reconstruction of the epidermis in the skin transplants is found which is regarded by the authors as a protective response to the persistent action of uncommon irritators. Early diagnosis of carcinoma in these cases is difficult and needs a detailed morphological examination of deep parts of the skin transplant. It is recommended, with a goal of prevention, to limit the use of the skin for the oesophagoplasty.
D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000473:pathology; D004937:Esophageal Fistula / Q000209:etiology / Q000473:pathology; D004938:Esophageal Neoplasms / Q000209:etiology / Q000473:pathology; D004944:Esophagoplasty / Q000009:adverse effects*; D004947:Esophagus / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000209:etiology / Q000473:pathology; D016038:Skin Transplantation; D013997:Time Factors
Patologiia iskusstvennykh pishchevodov iz kozhi.