Bronchial hyperresponsiveness to methacholine after exercise in asthmatics.
We studied the effect of exercise on bronchial responsiveness to methacholine in 10 asthmatics. Bronchial responsiveness to methacholine was compared before and 20 minutes after exercise. Although five out of 10 asthmatics showed exercise-induced bronchoconstriction (EIB), nine out of 10 asthmatics became more hypersensitive after exercise, irrespective of EIB.
D000328:Adult; D001249:Asthma / Q000139:chemically induced*; D001250:Asthma, Exercise-Induced / Q000139:chemically induced*; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D016210:Methacholine Chloride; D008688:Methacholine Compounds / Q000009:adverse effects*; D012129:Respiratory Function Tests
D008688:Methacholine Compounds; D016210:Methacholine Chloride