Invasive pulmonary aspergillosis complicating influenza A pneumonia in a previously healthy patient.
A rare occurrence of invasive pulmonary aspergillosis complicates influenza pneumonia in a previously healthy adult. Five other similar cases are reported in the literature. Both transient depression of cell-mediated immunity and loss of ciliary function in the tracheobronchial tree occurs during acute influenzal illness and may predispose to fungal superinfection. Early diagnosis and treatment of opportunistic Aspergillus infection complicating influenza is mandatory in view of the high mortality associated with this complication.
D000328:Adult; D001228:Aspergillosis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D009980:Influenza A virus; D007251:Influenza, Human / Q000150:complications*; D008172:Lung Diseases, Fungal / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D011014:Pneumonia / Q000150:complications*; D013601:T-Lymphocytes / Q000276:immunology