title: Age affects the induction dose of propofol ('Diprivan').
abstract: A standard method (fixed initial dose of 1.25 mg/kg followed by 10 mg every 15 s) for studying the induction dose of propofol showed a marked falling off in requirements in fit unpremedicated patients aged 60 y and over. With this slow technique of administration, side effects were rare, even in the elderly.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000771:Anesthesia, Intravenous; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010636:Phenols / Q000008:administration & dosage; D015742:Propofol
chemical_list: D010636:Phenols; D015742:Propofol