title: A hypernychthemeral sleep-wake syndrome: a treatment attempt.
abstract: The wake and sleep-onset times of a patient with a sleep-wake cycle longer than 24 hr were recorded by the patient for 4 years. During this time, the patient found himself unable to maintain a 24-hr sleep-wake schedule. When treated with 1-2 mg clonazepam, taken nightly, he was able to become entrained to a 24-hr day. Despite entrainment of his sleep-wake cycle, the patient reported depression, lack of motivation and fatigue and chose not to continue taking the drug.
mesh_terms: D000328:Adult; D002940:Circadian Rhythm; D002998:Clonazepam / Q000627:therapeutic use*; D003863:Depression / Q000209:etiology; D005221:Fatigue / Q000209:etiology; D006801:Humans; D008297:Male; D012893:Sleep Wake Disorders / Q000150:complications / Q000188:drug therapy*
chemical_list: D002998:Clonazepam