Prenatal diagnosis of congenital anomalies requiring surgical correction. Implications for the future.
With the use of maternal ultrasonography, 22 infants had an anomaly identified before delivery. Nine had gastrochisis. In all, ultrasonography was performed because of an elevated maternal serum alpha 1 fetoprotein level. Ultrasonography for other indications identified three infants with omphaloceles, three with cystic adenomatoid malformation of the lung, two with duodenal atresia, two with posterior urethral valves, and one each with obstruction of the ureteropelvic junction, a retroperitoneal teratoma, and an ovarian cyst. Infants were delivered in a neonatal center able to provide total care from the time of birth, thus the risks of transport over long distances were avoided. One of the infants with cystic adenomatoid malformation was incorrectly diagnosed as having a congenital diaphragmatic hernia, and the complete posterior urethral valve bilateral hydronephrosis complex was not identified in this infant until after delivery. The ability to diagnose complex anomalies correctly places new responsibilities on the surgeon who must counsel the parents on his ability to successfully treat the identified anomaly. Improved diagnostic accuracy, increased case findings, careful counselling, and delivery of high-risk infants in regional centers must be major priorities to improve neonatal surgical care in the next decade.
D000013:Congenital Abnormalities / Q000175:diagnosis* / Q000601:surgery; D003560:Cysts / Q000175:diagnosis / Q000601:surgery; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis; D006554:Hernia, Umbilical / Q000175:diagnosis / Q000601:surgery; D006555:Hernia, Ventral / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities / Q000601:surgery; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014463:Ultrasonography; D014551:Urinary Tract / Q000002:abnormalities / Q000601:surgery