title: The genetics of acute anterior uveitis.
abstract: Acute anterior uveitis (AAU), and the many diseases with which it is associated, may be inherited. The antigen HLA-B27, on the 6th chromosome, increases the risk of AAU twenty-fold. AAU is also associated with an unusual phenotype, MZ, on the 14th chromosome--particularly when the AAU is related to ankylosing spondylitis.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002901:Chromosomes, Human, 13-15; D002906:Chromosomes, Human, 6-12 and X; D006680:HLA Antigens / Q000032:analysis; D015796:HLA-B27 Antigen; D006801:Humans; D008875:Middle Aged; D010641:Phenotype; D013167:Spondylitis, Ankylosing / Q000150:complications; D014606:Uveitis, Anterior / Q000150:complications / Q000235:genetics* / Q000276:immunology; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D006680:HLA Antigens; D015796:HLA-B27 Antigen; D000515:alpha 1-Antitrypsin