Comparison of ICI 35868, etomidate and methohexitone for day-case anaesthesia.
The anaesthetic properties and side-effects of propofol 1.5 mg kg-1, etomidate 0.2 mg kg-1, and methohexitone 1.5 mg kg-1 were compared in 71 healthy female patients undergoing short gynaecological procedures. Propofol proved to be a safe and effective agent for induction and maintenance of anaesthesia and was associated with a lower incidence of side-effects than either etomidate or methohexitone.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000556:Ambulatory Surgical Procedures; D000771:Anesthesia, Intravenous / Q000009:adverse effects; D000773:Anesthesia, Obstetrical / Q000009:adverse effects; D000777:Anesthetics / Q000009:adverse effects; D001291:Attitude of Health Personnel; D005045:Etomidate / Q000009:adverse effects; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000009:adverse effects; D008723:Methohexital / Q000009:adverse effects; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D010636:Phenols / Q000009:adverse effects; D011247:Pregnancy; D015742:Propofol; D013997:Time Factors
D000777:Anesthetics; D007093:Imidazoles; D010636:Phenols; D008723:Methohexital; D015742:Propofol; D005045:Etomidate