title: [Specular microscopy in the diagnosis of the iridocorneal endothelial syndrome].
abstract: Irido-corneal endothelial syndrome regroups three disorders including: endotheliopathy, peripheral anterior synechiae and iris changes. According to the aspect of these abnormalities, three syndromes are described: essential iris atrophy, Chandler's syndrome and iris naevus (Cogan-Reese) syndrome. Endothelial changes studied by specular microscopy are typical: in early stages, a rounding off cell angles and intracellular blackout areas can be seen; in former stages, black out areas increase and there is a disruption of the regular mosaic. These features are a major point for differential diagnosis. We present six cases reports among which three where effectively diagnosed as iridocorneal endothelial syndrome and three were not.
mesh_terms: D000328:Adult; D000368:Aged; D001284:Atrophy; D002452:Cell Count; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000473:pathology; D003317:Corneal Dystrophies, Hereditary / Q000473:pathology*; D003937:Diagnosis, Differential; D004487:Edema / Q000473:pathology; D004727:Endothelium / Q000473:pathology; D005260:Female; D006801:Humans; D007498:Iris / Q000473:pathology*; D007499:Iris Diseases / Q000473:pathology; D008297:Male; D008853:Microscopy / Q000379:methods; D008875:Middle Aged; D009798:Ocular Hypertension / Q000209:etiology; D013577:Syndrome; D000267:Tissue Adhesions / Q000473:pathology
vernacular_title: Apport de la microscopie spéculaire dans le diagnostic du syndrome endothélial irido-cornéen.