Adrenaline and preeclampsia.
Twenty-one preeclamptic women had increased venous plasma-free adrenaline (45 +/- 5 vs 27 +/- 2 pg/ml, mean +/- SE, P less than 0.01) and plasma-free dopamine (137 +/- 25 vs 55 +/- 6 pg/ml, P less than 0.01) compared with fifteen normotensive pregnant women. Plasma renin activity (P less than 0.001) and aldosterone concentration (P less than 0.02) were depressed in the preeclamptic and serum potassium increased (P less than 0.02). Plasma adrenaline correlated with blood pressure (r=0.80, P less than 0.001) supporting increased sympathetic nervous tone in the development of preeclampsia.
D000328:Adult; D000450:Aldosterone / Q000097:blood; D004298:Dopamine / Q000097:blood; D004837:Epinephrine / Q000097:blood*; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D012083:Renin / Q000097:blood
D000450:Aldosterone; D012083:Renin; D004298:Dopamine; D004837:Epinephrine