title: Injection thrombosclerosis of esophageal varices.
abstract: It is now evident that injection sclerotherapy is a fast, effective method for controlling the acute variceal bleed. The results of sclerosis for control of acute variceal hemorrhage have been reported by many, including ourselves, and control rates vary from 78.0 to 95.0 per cent. Herein, we report a control rate of 94.7 per cent and a rebleeding rate of 22.0 per cent using a technical variation of sclerosis therapy. Thrombosclerosis is used soon after admission to the emergency room as a first line treatment to control variceal bleeding, often in lieu of the Sengstaken tube. Follow-up injections are scheduled at increasing intervals to achieve definitive control of the varices and are an essential feature of sclerotherapy as a management option.
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D004932:Esophageal and Gastric Varices / Q000150:complications* / Q000473:pathology / Q000628:therapy; D004947:Esophagus / Q000473:pathology; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D012597:Sclerosing Solutions