title: An immunological approach to vaccines against African swine fever virus.
abstract: Until recently there were no published reports of any immunological mechanism which could curtail the replication of African swine fever virus (ASFV). We have now described three such mechanisms--complement dependent lysis, antibody dependent cellular cytotoxicity and cytotoxic T lymphocytes. This paper discusses the likely role which each might play during ASFV infection and indicates where this research might help with a disease where no effective vaccine is available.
mesh_terms: D000357:African Swine Fever / Q000276:immunology / Q000517:prevention & control*; D000358:African Swine Fever Virus / Q000276:immunology*; D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D003165:Complement System Proteins / Q000276:immunology; D007497:Iridoviridae / Q000276:immunology*; D013552:Swine; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*; D014779:Virus Replication
chemical_list: D014765:Viral Vaccines; D003165:Complement System Proteins