[Surface morphologic changes of thymocytes in Ehrlich ascitic carcinoma-bearing mice].
The surface morphologic changes of thymocytes in Ehrlich ascitic carcinoma (EAC)-bearing mice were studied by scanning electronmicroscope. The changes were: marked atrophy of the thymus; rapid loss of surface microvilli; formation of the blebs of various sizes; roughening of cell surface and some twisty cells on day 10 after intraperitoneal injection of EAC (4 X 10(6) cell/mouse). These changes show that the early degeneration of the thymocytes takes place during the EAC development. The significance is discussed in detail.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000473:pathology*; D002470:Cell Survival; D008297:Male; D051379:Mice; D013601:T-Lymphocytes / Q000473:pathology*