Sympathetic factors in the cardiovascular complications of hypertension: evidence in genetic models for hypertension, stroke and atherosclerosis.
The role of the nervous system in the pathogenesis of cardiovascular complications in hypertension has been clarified to a great extent in genetic rat models for hypertension, stroke and atherosclerosis, especially in the evolution of cardiovascular hypertrophy in hypertension, the most common process related to the pathogenesis and complications of hypertension, in the development of stroke, one of the most common sequelae of hypertension itself and in the pathogenesis of atherosclerotic vascular diseases, the most usual cause of myocardial infarction.
D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology; D002319:Cardiovascular System / Q000294:innervation / Q000378:metabolism / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology; D003714:Denervation; D004195:Disease Models, Animal; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006984:Hypertrophy / Q000209:etiology; D066298:In Vitro Techniques; D051381:Rats; D011918:Rats, Inbred SHR / Q000502:physiology; D013564:Sympathetic Nervous System / Q000503:physiopathology*