Antitracheobronchospastic interaction in vitro and in vivo between salbutamol and flunisolide.
Salbutamol and flunisolide, when administered in association, are able to potentiate their effects both in vitro and in vivo on relaxation of the tracheobronchial smooth muscle of the guinea-pig.
D000109:Acetylcholine / Q000494:pharmacology; D000420:Albuterol / Q000494:pharmacology*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D001980:Bronchi / Q000187:drug effects* / Q000503:physiopathology; D001986:Bronchial Spasm / Q000503:physiopathology / Q000517:prevention & control; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005446:Fluocinolone Acetonide / Q000031:analogs & derivatives* / Q000494:pharmacology; D006168:Guinea Pigs; D066298:In Vitro Techniques; D014132:Trachea / Q000187:drug effects* / Q000503:physiopathology
D000893:Anti-Inflammatory Agents; D005446:Fluocinolone Acetonide; C007734:flunisolide; D000109:Acetylcholine; D000420:Albuterol