Met-enkephalin-Arg6-Gly7-Leu8 in large-cored vesicles of splanchnic nerve terminals innervating guinea pig adrenal chromaffin cells.
Met-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu)-like immunoreactivity in the guinea pig adrenal medulla was investigated by the peroxidase-antiperoxidase method for light microscopy and by the protein A-gold method for electron microscopy. Because of a distinct Met-Enk-Arg-Gly-Leu-like immunoreactivity in the splanchnic nerve terminals innervating the chromaffin cell, their distribution and structure were clearly demonstrated. With electron microscopy, specific colloidal gold particles representing Met-Enk-Arg-Gly-Leu were localized in large-cored vesicles.
D000313:Adrenal Medulla / Q000294:innervation* / Q000378:metabolism; D000818:Animals; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives* / Q000378:metabolism; D006168:Guinea Pigs; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D008297:Male; D008854:Microscopy, Electron; D013153:Splanchnic Nerves / Q000378:metabolism*; D013572:Synaptic Vesicles / Q000378:metabolism
D004744:Enkephalin, Methionine; C033453:enkephalin-Met, Arg(6)-Gly(7)-Leu(8)-