Localization of hematopoietic progenitor cells in tissue with the anti-My-10 monoclonal antibody.
Putative hematopoietic progenitor cells were localized in human lymphoid and nonlymphoid tissues with the use of the anti-My-10 antibody and avidin-biotin immunoperoxidase. Groups of My-10+ round mononuclear cells were evident in the splenic marginal zone near the follicular mantle. My-10+ cells were also evident in the hepatic portal triads and rare cells were seen near Peyer's patches. Except for My-10+ endothelial cells, there was no staining of the thymus, lymph node, skin, or kidney specimens.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008099:Liver / Q000166:cytology; D010581:Peyer's Patches / Q000276:immunology; D013154:Spleen / Q000166:cytology; D013234:Stem Cells / Q000033:anatomy & histology / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000166:cytology
D000911:Antibodies, Monoclonal