title: The use of sensory evoked potentials in toxicology.
abstract: The rationale for studying sensory systems as an integral part of neurotoxicological examinations is presented. The role of evoked potentials in assessing brain dysfunction in general and sensory systems in particular is also presented. Four types of sensory evoked potentials (brainstem auditory evoked response, somatosensory evoked potentials, flash evoked potentials, and pattern reversal evoked potentials) are discussed in terms of their demonstrated contributions to neurotoxicology and clinical neurology. Research needed to allow these methods to achieve their full value for neurotoxicology is identified and briefly discussed.
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000818:Animals; D000831:Animals, Newborn; D001933:Brain Stem / Q000502:physiology; D004558:Electric Stimulation / Q000379:methods; D005072:Evoked Potentials, Auditory / Q000187:drug effects; D005073:Evoked Potentials, Somatosensory / Q000187:drug effects*; D005074:Evoked Potentials, Visual / Q000187:drug effects; D006801:Humans; D008839:Microelectrodes; D009475:Neurons, Afferent / Q000502:physiology*; D009482:Neurophysiology / Q000295:instrumentation / Q000379:methods*; D009570:Nitriles; D010775:Photic Stimulation / Q000379:methods; D011722:Pyrethrins / Q000633:toxicity; D051381:Rats; D014267:Triethyltin Compounds / Q000633:toxicity
chemical_list: D009570:Nitriles; D011722:Pyrethrins; D014267:Triethyltin Compounds; C017180:decamethrin; C031575:triethyltin