A 99Tcm-labelled radiotracer for the investigation of cerebral vascular disease.
The first clinical data is given on 99Tcm-hexamethylpropyleneamine oxime (HM-PAO) in normal subjects and patients with established stroke. Regional cerebral blood flow maps (rCBF) have been recorded and displayed in tomographic mode with this new radiopharmaceutical. Good images were obtained, comparable to those achieved with 123I-isopropylamphetamine (IMP).
D000662:Amphetamines; D001921:Brain / Q000000981:diagnostic imaging; D002544:Cerebral Infarction / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D010091:Oximes; D011829:Radiation Dosage; D013667:Technetium; D019690:Technetium Tc 99m Exametazime; D014055:Tomography, Emission-Computed / Q000379:methods*
D000662:Amphetamines; D007457:Iodine Radioisotopes; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D013667:Technetium; D020367:Iofetamine