Cytophagic panniculitis and B cell lymphoma.
A 43-year-old woman had multiple, painful nodules of the legs and edema of both lower extremities for 3 years and leukopenia for 8 years. This histologic findings of lobular histiocytic panniculitis with "beanbag" cells were typical of cytophagic panniculitis. This case is unique in that B cell lymphoma developed in the spleen, as verified by immunoperoxidase staining, and demonstrates that the disease not only may be a progressive disease per se but also may be associated with nonhistiocytic malignancy.
D000328:Adult; D001402:B-Lymphocytes / Q000473:pathology; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000209:etiology* / Q000473:pathology; D010201:Panniculitis, Nodular Nonsuppurative / Q000150:complications* / Q000473:pathology; D011230:Precancerous Conditions / Q000473:pathology