title: Clinical experience with a new device that will simplify insulin injections.
abstract: In order to test clinically a newly developed, simple, and convenient device for giving multiple injections of short-acting insulin (Actrapid HM, Novo, Bagsvaerd, Denmark), 16 type I diabetic patients previously stabilized on intensified conventional therapy regimens participated in a randomized crossover study for a period of 6 wk. The patients used conventional syringes for injections of short-acting insulin during one period and the new device during the other. Conventional syringes were used for injections of basal insulin during both periods. Metabolic control was assessed by twice-weekly blood glucose profiles, HbA1c, and the frequency of hypoglycemic reactions; no significant differences were found during the two treatment periods. No infections at the injection sites were seen. Patients' evaluation of the new device was very positive.
mesh_terms: D000328:Adult; D002986:Clinical Trials as Topic; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy; D005260:Female; D006801:Humans; D007267:Injections / Q000295:instrumentation*; D007328:Insulin / Q000008:administration & dosage*; D061389:Insulin, Regular, Pork; D008297:Male; D008875:Middle Aged
chemical_list: D007328:Insulin; D061389:Insulin, Regular, Pork; C000006:insulin, neutral