Serial study of C reactive protein concentrations in cardiac allograft recipients.
C reactive protein (CRP) concentrations were measured serially in 38 patients after cardiac transplantation. Three of 28 patients (11%) had raised values before transplantation. After transplantation, most patients showed rises in CRP concentrations associated with transplant surgery which became normal by day 7. Thereafter, 75/274 samples (28%) from 18/38 patients (47%) had raised CRP values. Most of the rises in CRP concentration were associated with infection (78%), which in most cases was bacterial. No correlation was found between CRP values and acute cardiac rejection assessed histologically on serial endomyocardial biopsy.
D000328:Adult; D000961:Antilymphocyte Serum / Q000627:therapeutic use; D002097:C-Reactive Protein / Q000378:metabolism*; D003524:Cyclosporins / Q000627:therapeutic use; D006084:Graft Rejection; D016027:Heart Transplantation; D006801:Humans; D008875:Middle Aged; D013997:Time Factors
D000961:Antilymphocyte Serum; D003524:Cyclosporins; D002097:C-Reactive Protein