title: The pulpal response to dilute citric acid smear removers.
abstract: The aim of this study was to determine the pulpal response to three dilute citric acid smear removers. Forty-eight vervet monkeys (Cercopithecus aethiops pygerythrus), in three groups of sixteen animals provided 384 tooth specimens for the histological evaluation of the pulpal response at 3, 31, and 59 days post-operatively. Labial Class V cavities were prepared in the maxillary and mandibular incisor teeth. The pulpal responses elicited by 1% aqueous citric acid, 1% citric acid in 30% ethanol and 0.1% citric acid in 30% ethanol solutions, in unlined cavities and in cavities lined with Dycal after acid application, were compared with those elicited by a negative control material--(Nobetec), and a positive control material--(Syntrex). Using Stanley's criteria the most severe pulpal responses were seen in teeth treated with 1% aqueous citric acid and 1% citric acid in 30% ethanol without a subsequent liner, and by Syntrex at all three time intervals. The use of Dycal as a liner after smear removal markedly reduced the pulpal responses.
mesh_terms: D000134:Acid Etching, Dental; D000818:Animals; D002520:Cercopithecidae; D002951:Citrates / Q000494:pharmacology*; D019343:Citric Acid; D001840:Dental Bonding; D003737:Dental Cavity Preparation; D003782:Dental Pulp / Q000187:drug effects* / Q000473:pathology; D003804:Dentin / Q000187:drug effects / Q000473:pathology; D009804:Odontoblasts / Q000187:drug effects / Q000473:pathology; D012996:Solutions; D013997:Time Factors
chemical_list: D002951:Citrates; D012996:Solutions; D019343:Citric Acid