title: The treatment of childhood acute lymphoblastic leukemia based on the pharmacokinetics of methotrexate in serum and cerebrospinal fluid.
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001812:Blood-Brain Barrier; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007700:Kinetics; D007945:Leukemia, Lymphoid / Q000188:drug therapy* / Q000378:metabolism / Q000532:radiotherapy; D008297:Male; D008727:Methotrexate / Q000097:blood / Q000134:cerebrospinal fluid / Q000378:metabolism*
chemical_list: D008727:Methotrexate