Chronic relapsing myalgia (? Post viral): clinical, histological, and biochemical studies.
Two patients with persistent myalgia characterised by onset after an ill-defined systemic illness, marked fluctuations in the severity of the symptoms, and normal neuromuscular examination with the exception of variable muscle tenderness on deep palpation, may have a forme fruste of myalgic encephalomyelitis. Differentiation from psychogenic muscle pain is important in management. Muscle histology revealed non-specific Type II fibre atrophy. Mitochondrial respiration was assayed polarographically in intact organelles in vitro and revealed a mild depression of State 3 respiration rates with Site I and Site II substrates.
D000328:Adult; D002908:Chronic Disease; D004576:Electromyography; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008931:Mitochondria, Muscle / Q000378:metabolism; D009132:Muscles / Q000032:analysis; D009135:Muscular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D010101:Oxygen Consumption; D010146:Pain; D014777:Virus Diseases / Q000150:complications