title: Gynaecological tuberculosis: analysis of a personal series of 710 cases.
abstract: A study has been made of 710 patients with proved gynaecological tuberculosis investigated between January 1, 1951 and March 31, 1985. The main presenting symptoms in order of frequency were infertility, pelvic pain, excessive menstrual loss and amenorrhoea. The average age was 31 years at first attendance, only 16% of married women had been pregnant and palpable adnexal masses were found in 47%. Seven drug programmes have been used, the best results being obtained with the current regimen employing rifampicin, ethambutol and isoniazid. Where drug treatment failed, surgery under further drug cover was successfully employed. Toxic drug reactions occurred in 114 patients.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004334:Drug Administration Schedule; D004977:Ethambutol / Q000008:administration & dosage / Q000627:therapeutic use; D005184:Fallopian Tube Diseases / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000627:therapeutic use; D008875:Middle Aged; D010049:Ovarian Diseases / Q000175:diagnosis / Q000188:drug therapy; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D014384:Tuberculosis, Female Genital / Q000175:diagnosis / Q000188:drug therapy; D014591:Uterine Diseases / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin