Connection between two peripherical markers in a group of asthmatic patients.
We have studied the goniometric value of the tda angle and the alpha 1 antitrypsin phenotypes in a group of thirty atopic patients with the following patterns: 1) they were affected with asthma, atopic dermatitis and rhinitis. 2) they presented positive prick skin tests for pneumo-allergens and had. 3) positive allergic antecedents. There exists a significant statistical value for the lower tda angle in the right hand, in the MZ phenotypes of alpha 1 antitrypsin bearers, with P less than 0.05 significance. In the left hand there are many individual values that are identical (62% of the total test effected) thus the statistical methods cannot be applied satisfactorily, bearing in mind the significant difference as the statistical group recognized. From this and other previous works, we can conclude that an individual whose right hand tda angle reaches values near 75%, and with a MZ phenotype of alpha 1 antitrypsin, has a greater possibility of pertaining to one of the groups of asthma, atopic dermatitis and rhinitis symptomatology.
D001249:Asthma / Q000235:genetics*; D003876:Dermatitis, Atopic / Q000235:genetics; D003878:Dermatoglyphics; D004198:Disease Susceptibility; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000235:genetics*; D007428:Intradermal Tests; D008297:Male; D010641:Phenotype; D012220:Rhinitis / Q000235:genetics; D000515:alpha 1-Antitrypsin / Q000097:blood* / Q000235:genetics
D000515:alpha 1-Antitrypsin