title: Application of the log-linear model in the prediction of the antinuclear antibody test in the dog.
abstract: To find possible associations between antinuclear antibody (ANA) pattern, ANA titer, and certain clinical changes and clinical laboratory test results in dogs, the veterinary medical records of 111 ANA-positive and 126 ANA-negative dogs were examined. Variables could not be found that had significant associations with ANA pattern (unlike the results in persons), because of the predominance of 2 patterns. A log-linear model for ANA titer adequately fit the observed frequency and included 2-way interactions between titer and polyarthritis, titer and hematologic disorders, and polyarthritis and lymphadenopathy.
mesh_terms: D000818:Animals; D000974:Antibodies, Antinuclear / Q000276:immunology*; D001327:Autoimmune Diseases / Q000276:immunology / Q000662:veterinary*; D004283:Dog Diseases / Q000276:immunology*; D004285:Dogs
chemical_list: D000974:Antibodies, Antinuclear