[Comparative experimental study of the effect of melatonin and 5-methoxytryptamine on the thyroid gland of rats].
The authors studied the reactivity of the pituitary-thyroid system as influenced by melatonin and mexamine at varying times of photoperiod. It is concluded that the drugs under study had uncertain effects on rat thyroid function. It is assumed that different components of the hypothalamus-pituitary-thyroid system experience seasonal alterations in the sensitivity to the action of pineal gland methoxyindoles.
D008735:5-Methoxytryptamine / Q000494:pharmacology*; D000818:Animals; D006728:Hormones / Q000008:administration & dosage; D007274:Injections, Intraperitoneal; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D010903:Pituitary Gland, Anterior / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012621:Seasons; D013961:Thyroid Gland / Q000187:drug effects* / Q000378:metabolism; D013972:Thyrotropin / Q000037:antagonists & inhibitors; D013974:Thyroxine / Q000037:antagonists & inhibitors; D013997:Time Factors; D014284:Triiodothyronine / Q000037:antagonists & inhibitors; D014363:Tryptamines / Q000494:pharmacology*
D006728:Hormones; D014363:Tryptamines; D014284:Triiodothyronine; D008735:5-Methoxytryptamine; D013972:Thyrotropin; D008550:Melatonin; D013974:Thyroxine
Sravnitel'noe izuchenie vliianiia melatonina i 5-metoksitriptamina na shchitovidnuiu zhelezu krys v eksperimente.