title: [Possible intervention of immune mechanisms in the genesis and course of human atherosclerosis].
abstract: Aortas, coronary and carotid arteries from 31 patients who died of myocardial or cerebral infarction were examined by direct immunoenzymatic tests (using peroxidase-labelled anti human IgG sheep Fab or anti human complement sheep IgG) and compared to those of 9 patients who died of non atherosclerotic diseases. Immunoglobulins and complement bound to all atherosclerotic lesions, all elastic fiber alterations, all lipid infiltration in patients who died of atherosclerosis, as well as in patients who died of various other causes. Binding was generally more intensive in patients who died of atherosclerosis and in arteries irrigating infarcted areas. These data are discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001011:Aorta / Q000276:immunology; D001158:Arteries / Q000276:immunology*; D001161:Arteriosclerosis / Q000209:etiology / Q000276:immunology*; D002339:Carotid Arteries / Q000276:immunology; D002544:Cerebral Infarction / Q000276:immunology; D003165:Complement System Proteins / Q000032:analysis; D003331:Coronary Vessels / Q000276:immunology; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000276:immunology; D013997:Time Factors
chemical_list: D007136:Immunoglobulins; D003165:Complement System Proteins
vernacular_title: Possible intervention de mécanismes immuns dans la genèse et l'evolution de l'athérosclérose humaine.