Fresh small-fragment osteochondral allografts. Long-term follow-up study on first 100 cases.
Of 100 patients receiving fresh osteochondral fragment allografts, 95 had replacement of the weight-bearing portion of the knee. The allografts excised under sterile conditions were stored in Ringer's lactate at 4 degrees and transplanted into recipients within 24 hours. The average follow-up time was 3.8 years. One-half of the patients had allografts because of traumatic injury, and the best results (75% success) were obtained in this group of patients. The overall results were not encouraging for patients with osteoarthritis or spontaneous osteonecrosis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D016025:Bone Transplantation; D002358:Cartilage, Articular / Q000637:transplantation*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007593:Joint Instability / Q000209:etiology; D007718:Knee Injuries / Q000601:surgery; D007719:Knee Joint / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D013978:Tibial Fractures / Q000601:surgery; D014184:Transplantation, Homologous