title: Neuroblastoma.
abstract: Neuroblastoma originates in the adrenal medulla or anywhere in the body that sympathetic tissue normally is present. It may present with a variety of symptoms due to primary tumor, metastatic disease, or unusual signs and symptoms such as opsoclonus-myoclonus or severe diarrhea. Despite the fact that this neoplasm responds to a variety of therapeutic modalities, it remains one of the most frustrating and difficult childhood tumors to treat and cure.
mesh_terms: D000005:Abdomen; D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000473:pathology; D000971:Antineoplastic Combined Chemotherapy Protocols; D001855:Bone Marrow Diseases / Q000473:pathology; D001859:Bone Neoplasms / Q000556:secondary; D002395:Catecholamines / Q000652:urine; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005728:Ganglia, Sympathetic / Q000473:pathology; D006801:Humans; D007223:Infant; D009367:Neoplasm Staging; D009423:Nervous System Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D009447:Neuroblastoma / Q000378:metabolism / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D011379:Prognosis; D012878:Skin Neoplasms / Q000473:pathology
chemical_list: D002395:Catecholamines