title: Immunohistochemical identification of alpha-1-antitrypsin, alpha-1-antichymotrypsin, and lysozyme in focal hyperplastic gingivitis.
abstract: Tissues from twenty-four patients with focal hyperplastic gingival lesions containing calcification were stained for lysozyme (muramidase), alpha-1-antitrypsin, and alpha-1-antichymotrypsin. In eighteen of the twenty-four cases the tissues stained positively for lysozyme, and in all instances the tissues stained positively for alpha-1-antitrypsin and alpha-1-antichymotrypsin. These data suggest that the fibrous components of these lesions are derived from tissue histiocytes.
mesh_terms: D002114:Calcinosis / Q000201:enzymology / Q000473:pathology; D002918:Chymotrypsin / Q000037:antagonists & inhibitors* / Q000378:metabolism; D005885:Gingival Hyperplasia / Q000201:enzymology / Q000473:pathology; D005891:Gingivitis / Q000201:enzymology* / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007120:Immunochemistry; D009113:Muramidase / Q000378:metabolism*; D009808:Odontogenic Tumors / Q000201:enzymology / Q000473:pathology; D000514:alpha 1-Antichymotrypsin; D000515:alpha 1-Antitrypsin / Q000378:metabolism*
chemical_list: D000514:alpha 1-Antichymotrypsin; D000515:alpha 1-Antitrypsin; D009113:Muramidase; D002918:Chymotrypsin