Langerhans cells in labial minor salivary glands in primary Sjögren's syndrome.
Langerhans cells were demonstrated among the mononuclear cells in inflamed labial minor salivary glands in a patient with primary Sjögren's syndrome. Langerhans cells were visualized by the monoclonal antibody, OKT6, by an indirect immunofluorescence technique. The possible role of Langerhans cells as antigen-presenting cells in diseased glandular tissue in primary Sjögren's syndrome must be further studied.
D000368:Aged; D000911:Antibodies, Monoclonal; D000938:Antigen-Presenting Cells / Q000473:pathology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007801:Langerhans Cells / Q000276:immunology / Q000473:pathology*; D012469:Salivary Glands / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000276:immunology / Q000473:pathology*; D012859:Sjogren's Syndrome / Q000276:immunology / Q000473:pathology*
D000911:Antibodies, Monoclonal