title: [Pharmacokinetics and tissue penetration of ceftriaxone].
abstract: This article describes the pharmacokinetics of ceftriaxone, a new "third generation" cephalosporin. This antibiotic displays two major characteristics: a very long serum half-life and a good tissue penetration. The properties of ceftriaxone should allow its easy clinical handling.
mesh_terms: D001646:Bile / Q000378:metabolism; D002439:Cefotaxime / Q000031:analogs & derivatives* / Q000097:blood / Q000378:metabolism; D002443:Ceftriaxone; D004058:Diffusion; D005260:Female; D006801:Humans; D007668:Kidney / Q000378:metabolism; D007674:Kidney Diseases / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008107:Liver Diseases / Q000378:metabolism; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011485:Protein Binding; D014018:Tissue Distribution
chemical_list: D002443:Ceftriaxone; D002439:Cefotaxime
vernacular_title: Pharmacocinétique et diffusion tissulaire de la ceftriaxone.