[Comparative effects of netilmicin and 4 other aminoglycosides on 1028 bacterial strains isolated in a hospital milieu].
The activity of netilmicin and four other aminoglycosides was studied by a diffusion method against 1 028 bacterial strains isolated in hospital. Nearly all the strains of Gram-negative bacilli were susceptible to amikacin; with netilmicin, tobramycin, gentamicin and dibekacin the percentages of susceptible strains were smaller, without any statistically significant differences between them. Amikacin and netilmicin were the most effective compounds against staphylococci. Netilmicin seemed to be the most effective compound, in vitro, against streptococci. The MIC of gentamicin and netilmicin of 224 strains showed the superior activity of netilmicin against K. pneumoniae, Proteus, P. aeruginosa and S. aureus.
D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests; D009428:Netilmicin / Q000494:pharmacology
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D009428:Netilmicin
Activité comparée de la nétilmicine et de quatre autres aminosides sur 1 028 souches bactériennes isolées en milieu hospitalier.