Rate of tryptophan hydroxylation in vivo in brain nuclei of genetically hypertensive rats of the Lyon strain.
The rate of tryptophan hydroxylation in vivo is unaltered in brain areas of 5, 9 and 21 week-old Lyon genetically Hypertensive (LH) rats as compared to both Lyon Normotensive (LN) and Low Blood Pressure (LL) rats, except for a decrease in the C1 area of the medulla oblongata in 9 week-old animals.
D006916:5-Hydroxytryptophan / Q000378:metabolism; D000375:Aging; D000818:Animals; D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D001921:Brain / Q000378:metabolism*; D006834:Hydrazines / Q000494:pharmacology; D006900:Hydroxylation; D006973:Hypertension / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism; D008526:Medulla Oblongata / Q000378:metabolism; D011903:Raphe Nuclei / Q000378:metabolism; D051381:Rats; D011922:Rats, Mutant Strains; D014364:Tryptophan / Q000378:metabolism*
D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D006834:Hydrazines; D014364:Tryptophan; C004297:3-hydroxybenzylhydrazine; D006916:5-Hydroxytryptophan