title: Metabolic responses to physical training in young insulin-dependent diabetics.
abstract: Insulin-dependent (type 1) diabetics, aged 14-17 years, were studied according to two protocols. During a 6-month training period of moderate intensity (six participants) the aerobic work capacity and the erythrocyte insulin binding increased by 19% and 28%, respectively. Glycosylated haemoglobin (HbA1) was not significantly reduced. A 2-week intensive physical training program (10 participants) was associated with a 50% decrease of blood glucose values, which did not last beyond the training period. Plasma ketone bodies were markedly reduced. We conclude that young type 1 diabetics may participate in strenuous, short-term physical training. The improved aerobic work capacity and increased cellular insulin binding observed during training of moderate intensity is of potential benefit in the long-term management of the patients.
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000503:physiopathology; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood; D008297:Male; D005082:Physical Exertion; D012119:Respiration
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin; D008055:Lipids