Intracranial granuloma caused by Aspergillus fumigatus.
A case is reported of intracranial granuloma caused by Aspergillus fumigatus involving the anterior cranial fossa and the frontal lobe. In this case, clinical symptoms developed about 5 years before the diagnosis was made. The final diagnosis was made by a craniotomy. The patient was treated with an extensive excision and chemotherapy, but finally he failed to respond to these treatments. We compile a summary of reported cases with a tabulation of pertinent information and discuss the pathogenesis, prognosis, and difficulty in treating this infection.
D001228:Aspergillosis / Q000150:complications*; D001232:Aspergillus fumigatus; D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery; D002533:Cerebral Angiography; D006259:Craniocerebral Trauma / Q000150:complications; D005625:Frontal Lobe; D006099:Granuloma / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012886:Skull; D014057:Tomography, X-Ray Computed