Correlation between sexual phenotype and X-chromosome inactivation pattern in the X*XY wood lemming.
Replication patterns of the X chromosomes were studied in X*XY wood lemmings with male and female phenotypes. The wild-type X was late replicating (ie, inactivated) in all cells of the X*XY female, whereas the mutated X* was late replicating in all cells of the X*XY male. These findings are compared with those obtained in sex-reversed (Sxr) mice.
D000818:Animals; D003411:Arvicolinae / Q000235:genetics*; D002871:Chromosome Banding; D004261:DNA Replication; D004303:Dosage Compensation, Genetic; D005260:Female; D007621:Karyotyping; D008297:Male; D010641:Phenotype; D012098:Reproduction; D012730:Sex Chromosomes / Q000502:physiology*; D012732:Sex Determination Analysis