title: [Neonatal antinuclear antibodies and the lupus syndrome].
abstract: Neonatal lupus syndrome can be considered as being associated with pregnancy in women with lupus. Two antinomic cases are reported: a pregnancy in a woman presenting with Sjögren's syndrome, bearing a child with neonatal lupus syndrome (atrioventricular block and antinuclear antibodies) and a pregnancy in a woman presenting with lupus and giving birth to a normal child with antinuclear antibodies. These 2 case reports allow us to speculate on the pathophysiology of neonatal lupus syndromes in which the type of antinuclear antibodies seems to play a major role.
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000145:classification / Q000276:immunology*; D005260:Female; D006327:Heart Block / Q000151:congenital; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007231:Infant, Newborn; D008180:Lupus Erythematosus, Systemic / Q000151:congenital / Q000276:immunology*; D008431:Maternal-Fetal Exchange; D010641:Phenotype; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D012859:Sjogren's Syndrome / Q000276:immunology*; D013997:Time Factors
chemical_list: D000974:Antibodies, Antinuclear; D007074:Immunoglobulin G
vernacular_title: Anticorps antinucléaires néonatals et syndrome lupique.