Alpha 1-antitrypsin types in schizophrenia.
The gene and phenotype frequencies of alpha 1-antitrypsin were studied in patients with (49) and without (92) a family history of schizophrenia. A significant difference with respect to phenotype (p less than 0.05) and gene (p less than 0.025) frequencies was found between the two groups of patients. Among patients with a family history of schizophrenia there was a significant increase of the M1 gene and a decrease of the M2 gene. There were no significant differences between schizophrenic patients and controls.
D005787:Gene Frequency; D005796:Genes; D005819:Genetic Markers; D006801:Humans; D010641:Phenotype; D012559:Schizophrenia / Q000235:genetics*; D000515:alpha 1-Antitrypsin / Q000235:genetics*; D019896:alpha 1-Antitrypsin Deficiency
D005819:Genetic Markers; D000515:alpha 1-Antitrypsin