Serological and clinical remission in systemic lupus erythematosus.
The frequency of a combined clinical and serological remission in patients with systemic lupus erythematosus (SLE) was examined. Thirteen (4%) of 305 patients had both a seroconversion from a positive to a negative ANA and became asymptomatic in respect to their SLE. These remissions lasted from 6 months to 13 years. It is not clear what role, if any, therapy played in these remissions. Nevertheless, these remissions provided hope for the patients and their physicians.
D000293:Adolescent; D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis*; D002648:Child; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008875:Middle Aged; D012075:Remission, Spontaneous; D013997:Time Factors
D000974:Antibodies, Antinuclear