[Age-related characteristics of lipid peroxidation in the blood in alloxan diabetes].
The experiments on male rats aged 5-6 and 24-26 months have shown that alloxan diabetes is characterized by an increase in the content of blood glucose, total lipids and malonic dialdehyde. The time-course of these parameters reveals clear age dependence; the glucose and total lipid content is higher in young rats and that of lipid peroxidation products in old animals. The antioxidant effect of insulin, which is estimated by the malonic, dialdehyde content in the blood, decreases with age.
D000375:Aging; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003921:Diabetes Mellitus, Experimental / Q000097:blood*; D007328:Insulin / Q000494:pharmacology; D008054:Lipid Peroxides / Q000097:blood*; D008055:Lipids / Q000097:blood; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains
D001786:Blood Glucose; D007328:Insulin; D008054:Lipid Peroxides; D008055:Lipids; D008315:Malondialdehyde
Vozrastnye osobennosti perekisnogo okisleniia lipidov v krovi pri alloksanovom diabete.