title: C6 polymorphism in Japanese: typing by agarose gel isoelectric focusing-immunofixation.
abstract: Agarose gel isoelectric focusing was used to investigate the genetic polymorphism of the sixth component of complement (C6) in Japanese. C6 patterns were visualized by the immunofixation procedure. The allele frequencies calculated from 135 individuals were as follows: C6*A = 0.467, C6*B = 0.481, C6*B2 = 0.037, and C6*B3 = 0.015. It is suggested that C6*B3 is the fourth common allele characterizing the Japanese population.
mesh_terms: D000328:Adult; D000483:Alleles; D001797:Blood Protein Electrophoresis; D002648:Child; D003183:Complement C6 / Q000032:analysis / Q000235:genetics*; D004587:Electrophoresis, Agar Gel; D005260:Female; D005787:Gene Frequency; D006462:Hemolytic Plaque Technique; D006801:Humans; D007525:Isoelectric Focusing; D007564:Japan; D008297:Male; D011110:Polymorphism, Genetic; D011247:Pregnancy; D014430:Twins, Monozygotic
chemical_list: D003183:Complement C6