title: [Beta 2-microglobulin test in the diagnosis of chronic kidney diseases].
abstract: A study was made of the content of low molecular protein B2-microglobulin in the blood and urine of 126 patients with chronic renal diseases and 95 healthy persons. As a result of the study it was shown that B2-microglobulin concentration in the blood grows with age. The maximum level of B2-microglobulin was marked in patients with chronic glomerulonephritis. A high level of the urinary excretion of B2-microglobulin with a moderate rise of its concentration in the blood is typical of patients with chronic pyelonephritis during exacerbation. Indices of the B2-microglobulin test are closely related to renal function. The B2-microglobulin test is of great diagnostic significance as it provides an opportunity to establish the nature of proteinuria, site and expression of renal pathologic processes.
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011866:Radioisotope Renography; D012016:Reference Values; D001613:beta 2-Microglobulin / Q000032:analysis* / Q000652:urine
chemical_list: D001613:beta 2-Microglobulin
vernacular_title: Test na beta 2-microglobulin v diagnostike khronicheskikh zabolevaniĭ pochek.