title: Esophageal transection fails to salvage high-risk cirrhotic patients with variceal bleeding.
abstract: A small proportion of portal hypertensive patients with acute variceal bleeding do not respond to medical management and require emergency control of hemorrhage, yet are not candidates for shunt surgery. Transgastric esophageal transection and stapling of the esophagus has been suggested as a rapid, simple means to halt variceal bleeding in such high-risk patients. This should theoretically allow a hemorrhage-free interval for resuscitation and improvement in metabolic and cardiopulmonary status before definitive shunt surgery. We tested this hypothesis in 10 high-risk patients with variceal bleeding who underwent transection of the esophagus, sometimes with splenectomy and coronary vein ligation, over a 4 year period. In our experience, esophageal transection in high-risk patients with variceal bleeding controlled acute variceal hemorrhage, was neither rapid nor free of technical misadventures, was associated with a high rate of serious postoperative complications resulting in death in nearly all patients, and consistently failed to result in sufficient metabolic improvement to permit shunt surgery.
mesh_terms: D000328:Adult; D000368:Aged; D004630:Emergencies; D004932:Esophageal and Gastric Varices / Q000601:surgery*; D004944:Esophagoplasty; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000601:surgery*; D006521:Hepatitis, Chronic / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis