Stimulating effect of gold trichloride on DNA synthesis of human lymphoid cells.
The effect of gold trichloride on DNA synthesis of human thymocytes and peripheral blood lymphocytes was tested. A stimulation was obtained in both cell types with a concentration of 6-50 micrograms/ml. Gold trichloride may thus not be used in a lymphocyte transformation test for the diagnosis of contact allergy.
D000328:Adult; D002648:Child; D004247:DNA / Q000096:biosynthesis*; D006046:Gold / Q000494:pharmacology*; D017612:Gold Compounds; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000187:drug effects* / Q000378:metabolism; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism
D017612:Gold Compounds; C038016:gold chloride; D006046:Gold; D004247:DNA