Apomorphine has no effect on plasma homovanillic acid in schizophrenic patients.
Previous experiments suggest that pharmacological perturbations of the brain dopaminergic system may be reflected by concentrations of plasma homovanillic acid. This study examined the ability of low-dose apomorphine to reduce plasma homovanillic acid concentrations in schizophrenic patients chronically treated with neuroleptics. The data suggest that apomorphine does not reduce plasma homovanillic acid in those patients.
D000328:Adult; D001058:Apomorphine; D006220:Haloperidol / Q000627:therapeutic use*; D006719:Homovanillic Acid / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000097:blood / Q000188:drug therapy; D012559:Schizophrenia / Q000097:blood* / Q000188:drug therapy
D006220:Haloperidol; D001058:Apomorphine; D006719:Homovanillic Acid