title: The association of neuroblastoma and myoclonic encephalopathy: an imaging approach.
abstract: Myoclonic encephalopathy is a unique clinical syndrome of infants and children that is associated with a neurogenic tumor of ganglion-cell origin in approximately half of cases. A review of the literature as well as our personal experience with two recent infants suggests an imaging approach that includes chest radiography and abdominal computed tomography (CT). Ultrasonography, neck CT, and chest CT myelography may be required in selected patients. An expedient clinical and imaging evaluation of infants and children with opsomyoclonus is important to detect those patients with neurogenic tumors.
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis; D002524:Cerebellar Ataxia / Q000209:etiology*; D005133:Eye Movements; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis; D006801:Humans; D007223:Infant; D009207:Myoclonus / Q000209:etiology*; D009447:Neuroblastoma / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D010386:Pelvic Neoplasms / Q000175:diagnosis; D013577:Syndrome; D013899:Thoracic Neoplasms / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography