title: Statistical comparison of Pearl rates.
abstract: Statistical procedures for hypothesis testing and interval estimation of the difference in a pair of Pearl rates are presented. The p value of the test statistic is evaluated exactly from the binomial distribution or approximately from the standard normal distribution. Interval estimation is provided by the test-based method of Miettinen. The procedures are applied to two published data sets, and the conceptual link between the Pearl rate and life-table methods is discussed.
mesh_terms: D000206:Actuarial Analysis; D002986:Clinical Trials as Topic; D003267:Contraception; D003276:Contraceptives, Oral; D005260:Female; D006801:Humans; D007434:Intrauterine Devices; D011247:Pregnancy; D011336:Probability; D013223:Statistics as Topic
chemical_list: D003276:Contraceptives, Oral