title: Estrogen receptors in human goitrous and neoplastic thyroid.
abstract: An attempt was made to quantify the number of specific estrogen binding sites in specimens of human goitrous or neoplastic thyroid tissue obtained by surgery. Using synthetic estrogen [3H]moxestrol as a radioligand, the concentrations of estrogen receptors found were very low (average 0.57 +/- 0.47 fmol mg-1 of protein) approaching the detection limit. Accordingly, no significant sex dependent differences in estrogen receptors could be revealed.
mesh_terms: D045166:Estradiol Congeners / Q000378:metabolism; D004997:Ethinyl Estradiol / Q000031:analogs & derivatives / Q000378:metabolism; D005260:Female; D006042:Goiter / Q000378:metabolism*; D006801:Humans; D008297:Male; D011960:Receptors, Estrogen / Q000032:analysis* / Q000378:metabolism; D013964:Thyroid Neoplasms / Q000378:metabolism*
chemical_list: D045166:Estradiol Congeners; D011960:Receptors, Estrogen; D004997:Ethinyl Estradiol; C011310:moxestrol