Splenectomy for massive splenomegaly.
The technique, and short and long term results, of splenectomy for massive splenomegaly are presented. The latter was defined as a spleen weighing in excess of 1.5 kg. Thirty-five of the 38 patients had a serious haematological disorder as the indication for the operation, usually non-Hodgkin's lymphoma or myelofibrosis. All operations were carried out through abdominal incisions. Accessible splenic attachments were divided, and the splenic artery was ligated in continuity, prior to posterior mobilization. Two patients (5.3%) died as a result of the operation, both deaths being due to sepsis. Septic and thrombo-embolic complications were common, and occurred both early and late after the operation. Overall, eight of the 12 deaths during the first postoperative year were due to the primary disease, whereas all of the five deaths after that time were due to causes other than the primary disease. Twenty-four patients lived at least 1 year, and 10 patients are alive for more than 5 years.
D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D008223:Lymphoma / Q000150:complications; D008722:Methods; D011183:Postoperative Complications; D055728:Primary Myelofibrosis / Q000150:complications; D013156:Splenectomy / Q000379:methods* / Q000401:mortality; D013163:Splenomegaly / Q000209:etiology / Q000601:surgery*