title: Production of high specific activity 123I for protein iodination for medical use.
abstract: Iodine-123 is produced via xenon-133 by irradiation of a sodium iodide target with 108 MeV deuterons from the synchrocyclotron of IPN. The on-line production method is described. The specific activity of the iodine is determined by neutron activation analysis and by a radioimmunological method. The conditions labelling different proteins (insulin, angiotensin) are given and also the purification method to obtain a product ready for injection to patients.
mesh_terms: D000809:Angiotensins; D000818:Animals; D006801:Humans; D007328:Insulin; D007457:Iodine Radioisotopes; D007553:Isotope Labeling / Q000379:methods
chemical_list: D000809:Angiotensins; D007328:Insulin; D007457:Iodine Radioisotopes