Adrenal myelolipoma in a woman with congenital 17-hydroxylase deficiency.
A case of adrenal myelolipoma, which to our knowledge is the first case to be associated with 17-hydroxylase deficiency, is reported. This rare, benign lesion is known to occur in association with other endocrinopathies. Discussion focuses on the possible role of continued stimulation by corticotropin and/or steroids as pathogenic factors. The present case adds evidence supporting this view.
D000310:Adrenal Gland Neoplasms / Q000209:etiology*; D000312:Adrenal Hyperplasia, Congenital / Q000150:complications; D005260:Female; D006801:Humans; D008067:Lipoma / Q000209:etiology*; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000209:etiology; D013250:Steroid Hydroxylases / Q000172:deficiency*
D013250:Steroid Hydroxylases