title: Transitional nephrology.
abstract: During growth from fetal life to early childhood, renal function and parameters used to assess renal function undergo developmental changes. This article provides a brief review of these maturational changes and how they affect the evaluation and management of young patients with diseases affecting the genitourinary system. Included is a discussion of renal blood flow, glomerular filtration, sodium and water balance, clinical assessment of renal function, and age-related effects of nephrotoxins.
mesh_terms: D000328:Adult; D000375:Aging; D000818:Animals; D001806:Blood Urea Nitrogen; D002648:Child; D002675:Child, Preschool; D003401:Creatine / Q000097:blood; D005314:Embryonic and Fetal Development; D005919:Glomerular Filtration Rate; D006801:Humans; D006869:Hydronephrosis / Q000628:therapy; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000254:growth & development* / Q000502:physiology; D007674:Kidney Diseases / Q000139:chemically induced; D007684:Kidney Tubules / Q000502:physiology; D011296:Prenatal Diagnosis; D012079:Renal Circulation; D012756:Sheep; D012964:Sodium / Q000378:metabolism; D014517:Ureteral Obstruction / Q000503:physiopathology; D014718:Vesico-Ureteral Reflux / Q000628:therapy; D014882:Water-Electrolyte Balance
chemical_list: D012964:Sodium; D003401:Creatine