[Biosynthesis of immunoreactive luteinizing hormone in the central nervous system of rats].
The authors detected the biosynthesis in vitro of the immunoreactive LH in the pineal gland and hypothalamus of rats using a specific immunosorbent to LH. The synthesis of this hormone was undetectable in the thalamus, striate body and in the cerebral cortex. Puromycin decreased the synthesis of the hormone in the pineal gland and hypothalamus by 40% and 60% respectively. LH-RH stimulated the biosynthesis of the immunoreactive LH in the pineal gland. It was assumed that LH-producing cells are present in the pineal gland and hypothalamus of rats.
D000818:Animals; D003470:Culture Media; D004347:Drug Interactions; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology; D006728:Hormones / Q000494:pharmacology; D006729:Hormones, Ectopic / Q000096:biosynthesis*; D007031:Hypothalamus / Q000378:metabolism*; D007163:Immunosorbent Techniques; D066298:In Vitro Techniques; D007986:Luteinizing Hormone / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D010870:Pineal Gland / Q000378:metabolism*; D011691:Puromycin / Q000494:pharmacology; D051381:Rats
D003470:Culture Media; D006728:Hormones; D006729:Hormones, Ectopic; D007987:Gonadotropin-Releasing Hormone; D011691:Puromycin; D007986:Luteinizing Hormone
Biosintez immunoreaktivnogo liuteiniziruiushchego gormona v tsentral'noĭ nervnoĭ sisteme krys.