[Serological diagnosis and immunological aspects of Proteus infection. V. Design and trial of polyvalent antigenic preparations].
The main principles of the development of Proteus polyvalent antigen and erythrocyte diagnosticum, including the selection of the initial strains according to the clinical importance of their H-antigens and to the variety of their partial factors, the combination of monoantigens to form a polyvalent antigenic preparation with due regard to the potency of each component and the use of the preparation in serological tests in accordance with its summary potency, as well as the simultaneous loading of formaldehyde-fixed and tannin- or bisdiazo benzidine-treated sheep red blood cells with sensitins, have been worked out. The diagnostic value of these preparations has been confirmed by the study of serum samples from 579 patients with intestinal and urological infections (among them 153 patients releasing Proteus) and 245 healthy persons.
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D000941:Antigens / Q000276:immunology / Q000302:isolation & purification; D000942:Antigens, Bacterial / Q000276:immunology / Q000302:isolation & purification*; D002648:Child; D002986:Clinical Trials as Topic; D004912:Erythrocytes / Q000276:immunology; D006801:Humans; D011512:Proteus Infections / Q000175:diagnosis* / Q000276:immunology; D011513:Proteus mirabilis / Q000276:immunology*; D011514:Proteus vulgaris / Q000276:immunology*; D012698:Serologic Tests / Q000379:methods
D000907:Antibodies, Bacterial; D000941:Antigens; D000942:Antigens, Bacterial; C022863:H antigen; C012031:sensitin
Serologicheskaia diagnostika i immunologicheskie aspekty proteĭnoĭ infektsii. Soobshchenie V. Konstruirovanie i ispytanie polivalentnykh antigennykh preparatov.