title: Heat-shock induction of radiation resistance in primordial germ cells of the fish Oryzias latipes.
abstract: The effects of heat on the radiosensitivity of primordial germ cells at the quiescent stage in the fish Oryzias latipes were studied. The results show: (1) heat preceding but not following irradiation induced radioresistance which was reflected by improved survival; (2) its magnitude was a function of the heating time before irradiation; (3) improved germ-cell survival did not change with time for up to at least 4 hours after heat treatment at 41 degrees C for 30 min; (4) this resistance was more prominently expressed in the subsequent course of proliferation of female germ cells than in the non-proliferating male germ cells. In conclusion, heat induced radiation resistance in primordial germ cells of the female at the quiescent stage; this probably allows the cells subsequently to escape reproductive death.
mesh_terms: D000818:Animals; D002347:Carps / Q000196:embryology; D002588:Cesium Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005720:Gamma Rays; D005854:Germ Cells / Q000528:radiation effects*; D006358:Hot Temperature; D008297:Male; D011836:Radiation Tolerance; D013997:Time Factors
chemical_list: D002588:Cesium Radioisotopes