[Primary results of rat experiments with long-term rotation in relation to the problem of artificial gravity].
Rats housed as a group per cage were centrifuged for 21 and 30 days at 1.1 and 2.0 G. The following parameters were measured: motor activity, body mass, static and dynamic endurance, acceleration (+Gz) tolerance, vestibular function, equilibrium function, skeletal muscle contractility, bone dynamics, gas exchange, blood biochemistry; weight of adrenals, thymus and thyroid gland; morphology of adrenals, thyroid gland, and cortex of the cerebellum nodulus; biochemistry of blood hormones, energy metabolism enzymes in the liver, bone phosphatases, myosin Ca-Mg-ATPase in the myocardium, protein sulfhydryl groups in the cerebellar motor cortex. The study has demonstrated that prolonged (1/50 of their life time) centrifugation of unrestrained rats causes no deterioration of many physiological functions, i.e., rotation produces no adverse effects on the animal body.
D000054:Acceleration; D000818:Animals; D001835:Body Weight; D004734:Energy Metabolism; D006112:Gravitation; D006706:Homeostasis; D009043:Motor Activity / Q000502:physiology; D009119:Muscle Contraction; D011659:Pulmonary Gas Exchange; D051381:Rats; D012399:Rotation; D013997:Time Factors; D014722:Vestibule, Labyrinth / Q000502:physiology
Osnovnye rezul'taty eksperimentov s dlitel'nym vrashcheniem krys primenitel'no k probleme iskusstvennoĭ sily tiazhesti.