title: Double-blind flea hyposensitization trial in cats.
abstract: In a double-blind clinical trial, flea antigen was injected subcutaneously or intradermally in cats with signs of fleabite allergic dermatitis. No significant clinical improvement was noted by the investigator or the owner in either antigen-treated or control groups over a 20-week period.
mesh_terms: D000818:Animals; D000941:Antigens / Q000008:administration & dosage; D002371:Cat Diseases / Q000628:therapy*; D002415:Cats; D002986:Clinical Trials as Topic / Q000662:veterinary; D003872:Dermatitis / Q000628:therapy / Q000662:veterinary*; D003888:Desensitization, Immunologic / Q000379:methods / Q000662:veterinary*; D004311:Double-Blind Method; D004478:Ectoparasitic Infestations / Q000628:therapy / Q000662:veterinary*; D005260:Female; D007271:Injections, Intradermal / Q000662:veterinary; D007279:Injections, Subcutaneous / Q000662:veterinary; D007299:Insect Bites and Stings / Q000628:therapy / Q000662:veterinary*; D008297:Male; D005423:Siphonaptera / Q000276:immunology
chemical_list: D000941:Antigens