Preoperative cefoxitin prophylaxis for elective abdominal hysterectomy.
Fifty women were randomly given one, two, or three 2 gm parenteral doses of cefoxitin with placebo blinding perioperatively at abdominal hysterectomy. A single preoperative intramuscular dose was more efficient, less frequently associated with the development of bacterial resistance, and less expensive than two or three doses.
D001424:Bacterial Infections / Q000517:prevention & control*; D002440:Cefoxitin / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control; D011292:Premedication
D002440:Cefoxitin