Detection and prevalence of serotypes of feline syncytial spumaviruses.
Three serotypes of feline syncytial virus (FSV) were detected by neutralisation tests: 906, a serotype of low prevalence and 702 and 951 which were serotypes of higher prevalence, between which a minor one-way antigenic difference was detected. Serum antibody in naturally-infected cats in some cases neutralised 951 but not 702 or 906 which suggested that 951 could be considered as a major distinct serotype. An increase in prevalence of antibody to FSV in cats over a 5 year period from 1977-1981 was detected by neutralisation, agar gel immunodiffusion, and fluorescent antibody techniques. Over the 5 year period the prevalence of antibody to the 951 serotype increased and the overall increase in prevalence of antibody to FSV during this period appeared to relate to dissemination of the 951 serotype.
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D002371:Cat Diseases / Q000382:microbiology; D002415:Cats / Q000382:microbiology*; D005455:Fluorescent Antibody Technique; D005779:Immunodiffusion; D009420:Nervous System / Q000382:microbiology; D009500:Neutralization Tests; D012190:Retroviridae / Q000145:classification* / Q000276:immunology / Q000302:isolation & purification; D012703:Serotyping
D000914:Antibodies, Viral