In vitro studies on the sensitivities of Plasmodium falciparum in Thailand to pyrimethamine and proguanil.
The susceptibility to pyrimethamine and proguanil of a strain of Plasmodium falciparum from Thailand was assessed by using blood from the same patient cultured by two different techniques. Irrespective of the technique used, the strain of P. falciparum appeared more sensitive to proguanil than to pyrimethamine.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D008826:Microbial Sensitivity Tests; D010274:Parasitology / Q000379:methods; D010963:Plasmodium falciparum / Q000187:drug effects*; D002727:Proguanil / Q000494:pharmacology*; D011739:Pyrimethamine / Q000494:pharmacology*; D013785:Thailand
D002727:Proguanil; D011739:Pyrimethamine