Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) with amyloid angiopathy.
A case is reported of Creutzfeldt-Jakob disease associated with amyloid infiltration of cerebral vessels. The duration of progressive dementia was only 4 months. Neuritic plaques were not a feature of the pathology. This report emphasises the association of spongiform encephalopathy with the presence of amyloid in the brain.
D000686:Amyloidosis / Q000473:pathology*; D001921:Brain / Q000473:pathology; D002536:Cerebral Arteries / Q000473:pathology; D002540:Cerebral Cortex / Q000098:blood supply; D002561:Cerebrovascular Disorders / Q000473:pathology*; D007562:Creutzfeldt-Jakob Syndrome / Q000473:pathology*; D006801:Humans; D008297:Male; D008578:Meninges / Q000098:blood supply; D008875:Middle Aged; D014680:Veins / Q000473:pathology