REV7, a new gene concerned with UV mutagenesis in yeast.
Three allelic mutations of a new yeast gene, which we have named REV7, have been isolated by testing 313 methyl methane sulfonate sensitive mutants for UV-induced reversion of a lys2 allele. Rev7 mutants are markedly deficient with respect to UV-induced reversion of lys2, are slightly sensitive to UV and appear to be in the RAD6 epistasis group for UV survival. Rev7-1, which is probably an amber mutation, does not appear to affect sporulation in homozygous diploids. The REV7 gene is located about 12 cM distal to HIS5 on chromosome IX.
D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004307:Dose-Response Relationship, Radiation; D005800:Genes, Fungal; D005816:Genetic Complementation Test; D007700:Kinetics; D008741:Methyl Methanesulfonate / Q000494:pharmacology; D009154:Mutation; D010641:Phenotype; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000235:genetics / Q000528:radiation effects*; D014466:Ultraviolet Rays
D008741:Methyl Methanesulfonate