Failure of 2-deoxy-D-glucose to stimulate feeding in deermice.
Deermice (Peromyscus maniculatus) did not increase their food intake above baseline following treatment with 2-deoxy-D-glucose (2DG, 500 or 1000 mg/kg). They did eat more following food deprivation or treatment with insulin at a high dose (100 U/kg). House mice (Mus musculus) showed hyperphagia to 2DG, low dose of insulin (5 U/kg) and deprivation.
D000818:Animals; D006224:Cricetinae; D003837:Deoxy Sugars / Q000494:pharmacology*; D003847:Deoxyglucose / Q000494:pharmacology*; D005247:Feeding Behavior / Q000187:drug effects* / Q000502:physiology; D005508:Food Deprivation / Q000502:physiology; D005849:Gerbillinae; D007328:Insulin / Q000494:pharmacology; D008297:Male; D008647:Mesocricetus; D051379:Mice; D010542:Peromyscus; D013045:Species Specificity
D003837:Deoxy Sugars; D007328:Insulin; D003847:Deoxyglucose