[Is it possible to improve erythrocyte deformability in vascular diseases in the aged? Preliminary study].
A study is presented of erythrocyte filtration in 10 elderly patients suffering from vasculopathy and treated with 1000 mg X 2 cyticholine per diem for six days. Statistical analysis using the Student's "t" test showed a distinct improvement in the filtration index in all stages of treatment with maximum values (p less than 0.001) reached on the 2nd day, two hours after endovenous administration of 1 g cyticholine.
D000367:Age Factors; D000368:Aged; D002794:Choline / Q000031:analogs & derivatives*; D002986:Clinical Trials as Topic; D003221:Confusion; D003566:Cytidine Diphosphate Choline / Q000627:therapeutic use*; D004341:Drug Evaluation; D004907:Erythrocyte Deformability / Q000187:drug effects*; D004910:Erythrocyte Membrane / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014652:Vascular Diseases / Q000097:blood* / Q000188:drug therapy / Q000523:psychology
D003566:Cytidine Diphosphate Choline; D002794:Choline
E' possibile migliorare la deformabilità eritrocitaria nell'anziano vasculopatico? Studio preliminare.