Aztreonam therapy for gram-negative pneumonia.
Nineteen patients with community- or hospital-acquired gram-negative pneumonia were treated with aztreonam. Other gram-negative antibiotics were withheld. Thirteen patients (68 percent) had clinical cures and 15 (79 percent) had microbiologic cures with aztreonam. No adverse reactions or drug toxicity occurred in this population.
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001398:Aztreonam; D001424:Bacterial Infections / Q000150:complications / Q000188:drug therapy*; D003428:Cross Infection / Q000188:drug therapy; D004334:Drug Administration Schedule; D004754:Enterobacter / Q000302:isolation & purification; D005260:Female; D006088:Gram-Negative Aerobic Bacteria / Q000302:isolation & purification*; D006323:Heart Arrest / Q000150:complications; D006801:Humans; D008297:Male; D009735:Nursing Homes; D011014:Pneumonia / Q000150:complications / Q000188:drug therapy*; D011513:Proteus mirabilis / Q000302:isolation & purification; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D013183:Sputum / Q000382:microbiology
D000900:Anti-Bacterial Agents; D001398:Aztreonam