[Chronic lymphocytic leukemia, erythroblastopenia, thymolipoma].
The association of B cell chronic lymphocytic leukemia and pure red cell aplasia in a 42 year-old patient led to the discovery of a thymic enlargement. After six weeks treatment including steroids, cyclophosphamide and three courses of plasma exchange without improvement, surgical thymectomy was followed by a reticulocytosis and remission of the red cell aplasia. The tumor was a thymolipoma. Characteristics of this are thymic tumor, his connections with pure red cell aplasia and in vitro differentiation of erythroid progenitors are discussed.
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications* / Q000188:drug therapy; D008067:Lipoma / Q000150:complications* / Q000601:surgery; D008297:Male; D012010:Red-Cell Aplasia, Pure / Q000150:complications* / Q000628:therapy; D013953:Thymus Neoplasms / Q000150:complications* / Q000601:surgery
D000970:Antineoplastic Agents
Leucémie lymphoïde chronique, érythroblastopénie, thymolipome.