Replication of rat coronavirus in a rat cell line, LBC. Brief report.
Rat coronavirus readily propagated and induced marked cytopathic effect in a rat cell line, LBC cell culture, which provided a sensitive, practical assay system for viral infectivity and neutralizing antibody, and a satisfactory source of the virus.
D000818:Animals; D002460:Cell Line; D003332:Coronaviridae / Q000254:growth & development / Q000502:physiology*; D003588:Cytopathogenic Effect, Viral; D005260:Female; D005455:Fluorescent Antibody Technique; D008325:Mammary Neoplasms, Experimental; D009500:Neutralization Tests; D051381:Rats; D011917:Rats, Inbred Lew; D014776:Virus Cultivation; D014779:Virus Replication