[Morphology and growth behavior of ovarian tumors. Studies using DNA cytophotometry, immunohistology and tissue culture].
Antigens A, B, Lea, Leb, CA 12-5, CA 19-9 and CEA were prepared immunohistologically, a DNA-cytophotometry was carried out and the value of a new in vitro proliferation assay to test cytostatic drugs investigated. Material was as follows: 20 normal ovaries and 105 ovarian tumors. Blood group antigens were expressed at a high percentage from well-differentiated epithelial cells, CEA in 50% and CA 12-5 in 70% of the ovarian carcinoma. Predictions about the dignity of borderline tumors can be made with DNA-cytophotometry. The efficacy of 6 different cytostatic agents was investigated in a new in vitro proliferation assay.
D000951:Antigens, Neoplasm / Q000032:analysis*; D002277:Carcinoma / Q000276:immunology / Q000473:pathology*; D002455:Cell Division; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003592:Cytophotometry; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D010051:Ovarian Neoplasms / Q000276:immunology / Q000473:pathology*; D010053:Ovary / Q000473:pathology; D014410:Tumor Stem Cell Assay
D000951:Antigens, Neoplasm; D004273:DNA, Neoplasm
Morphologie und Wachstumsverhalten von Ovarialtumoren. Untersuchungen mittels DNA-Zytophotometrie, Immunhistologie und Gewebekultur.