[Cephalic insulin secretion--neuromorphologic findings].
The paper presented deals with the electron microscopy bases of experimental results, which show a cephalic insulin secretion. The B cell-producing insulin--is a highly innervated endocrine cell. Several nerve endings often form synaptic connexions at a single B cell. The synaptic clefts are usually 20-25 nm. The nerve endings cause an evident impression of the cell membrane. The narrow neuro-cellular connexions form a structural bases of the cephalic insulin response. The interruption of this reflex loop caused by vagotomy eliminates cephalic mechanism. However, the innervation of the islets (electron microscopic examination) remains unaffected. Therefore the intramural nervous mechanism seems to be not excluded by vagotomy.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D002415:Cats; D004285:Dogs; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000294:innervation*; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000033:anatomy & histology; D009415:Nerve Net / Q000033:anatomy & histology; D013569:Synapses / Q000648:ultrastructure; D014630:Vagus Nerve / Q000033:anatomy & histology
D007328:Insulin
Die kephale Insulinsekretion--neuromorphologische Befunde.