Limb salvage in primary malignant bone tumors.
Advances in adjuvant chemotherapy and improvements in techniques of oncologic reconstruction have stimulated renewed interest in limb saving operation for malignant bone tumors. Between 1970 and 1981, 160 patients underwent local resection for malignant osseous lesions at the Mayo Clinic. This included 102 patients with chondrosarcoma, 44 with osteosarcoma, and 14 with fibrosarcoma. Ninety-three of the lesions were stage I and 67 were stage II. The overall local recurrence rate was 11.8%. The reconstructive procedures were effective in providing adequate functional restoration. Limb sparing operation is a valid viable option in carefully selected patients with malignant bone tumors. A continued search for effective adjuvant treatment programs is necessary.
D000328:Adult; D000671:Amputation, Surgical; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation; D002813:Chondrosarcoma / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005354:Fibrosarcoma / Q000601:surgery*; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D012516:Osteosarcoma / Q000601:surgery*; D011182:Postoperative Care; D019736:Prostheses and Implants