Blood glucose and insulin concentration in rats subjected to physical exercise in acute poisoning with parathion-methyl.
Unexercised rats or those subjected to single physical exercise were given parathion-methyl (10 mg/kg p.o. - 0.5 DL50) or oil (vehicle). Blood glucose and serum insulin concentration were assayed 1 h after the treatment. Physical exercise depressed the serum insulin concentration without changes in blood glucose level. In acute poisoning with parathion-methyl hyperglycemia occurred concurrently with hypoinsulinemia. Physical exercise abolished the pesticide-induced hypoinsulinemia, but not hyperglycemia.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D007328:Insulin / Q000097:blood*; D008297:Male; D008743:Methyl Parathion / Q000506:poisoning*; D010278:Parathion / Q000031:analogs & derivatives*; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains
D001786:Blood Glucose; D007328:Insulin; D008743:Methyl Parathion; D010278:Parathion