Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage.
The intake of anti-inflammatory drugs by 268 patients with colonic or small bowel perforation or haemorrhage was compared with that by a group of patients, matched for age and sex, with uncomplicated lower bowel disease. Patients with perforation or haemorrhage were more than twice as likely to be takers of anti-inflammatory drugs, but no association was detected with the intake of other types of drugs, particularly cardiovascular drugs. The association between complicated lower bowel disease and intake of anti-inflammatory drugs may be causal.
D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D002317:Cardiovascular Agents / Q000009:adverse effects; D003108:Colonic Diseases / Q000139:chemically induced*; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D006801:Humans; D007416:Intestinal Perforation / Q000139:chemically induced*; D007421:Intestine, Small
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D002317:Cardiovascular Agents