[Tubular involvement during non-oliguric rhabdomyolysis. (Apropos of 2 cases)].
The authors report two cases of severe rhabdomyolysis in a 23-year-old woman following a toxic coma with muscular compression and in a 34-year-old man after a febrile state. Despite clinical and biological signs of marked muscular necrosis, oliguric acute renal failure did not occur. However, repetitive urinary dosage of N-acetyl-glucosaminidase (NAG), of retinol-binding-protein (RBP) and of beta-2-microglobulin (beta-2-m) revealed an early and long-standing tubular dysfunction not suggested by conventional laboratory data.
D000118:Acetylglucosaminidase / Q000652:urine; D000328:Adult; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology / Q000503:physiopathology; D007684:Kidney Tubules / Q000503:physiopathology; D008297:Male; D012177:Retinol-Binding Proteins / Q000652:urine; D012206:Rhabdomyolysis / Q000150:complications* / Q000503:physiopathology / Q000652:urine; D001613:beta 2-Microglobulin / Q000652:urine
D012177:Retinol-Binding Proteins; D001613:beta 2-Microglobulin; D000118:Acetylglucosaminidase
Atteinte tubulaire au cours des rhabdomyolyses non oliguriques. (A propos de deux cas).