[Experimental diabetes mellitus induced by total pancreatectomy with preservation of the duodenum in dogs].
The total pancreatectomy without duodenectomy was carried out in 16 dogs. The postoperative diabetes mellitus leads to death on average until the 11th postoperative day. A prolongation of the survival time was possible only by an insulin injection or by pancreas transplantation. Bleedings and circulatory disturbances of the duodenum occurred in 3 of 16 dogs as a complication of the operation. The diabetes mellitus was confirmed by the estimation of the fasting blood glucose and the glucose stimulated plasma insulin concentration. The irreversible hyperglycemia syndrome after pancreatectomy proved as a pattern for the pancreas segmental transplantation.
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy / Q000503:physiopathology*; D004285:Dogs; D004386:Duodenum / Q000502:physiology*; D007328:Insulin / Q000627:therapeutic use; D010180:Pancreatectomy
D007328:Insulin
Experimenteller Diabetes mellitus durch Pankreatektomie mit Erhaltung des Duodenums beim Hund.