[Effect of phenytoin on Purkinje cells in the cerebellum].
We have examined the effect of chronic administration of phenytoin on Purkinje cells of cerebellum in adult mice. After daily intramuscular administration of phenytoin for a period of six months no difference in the number of Purkinje cells could be found between the treated and control animals.
D000818:Animals; D002531:Cerebellum / Q000166:cytology / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D010672:Phenytoin / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D011689:Purkinje Cells / Q000187:drug effects*; D013997:Time Factors
D010672:Phenytoin
Die Wirkung von Phenytoin auf die Purkinjezellen des Kleinhirns.