[Reversible renal insufficiency and arterial hypertension after renal transplantation: role of transplant artery stenosis and a captopril-furosemide combination].
Acute renal failure after captopril therapy in patients with transplant artery stenosis is well known. The study of a new observation may stress three particular points: 1) Diagnosis may be difficult just after transplantation in case of initial acute renal failure. 2) Renal function rapidly improved after withdrawing captopril and furosemide; after surgical treatment of the stenosis, a new course of captopril therapy was possible without any decrease of glomerular filtration rate. 3) A critical fall in filtration fraction seems to be the essential mechanism of renal failure, but specific interstitial lesions of the transplant showed on kidney biopsies, might be discussed.
D058186:Acute Kidney Injury / Q000209:etiology*; D000328:Adult; D002216:Captopril / Q000009:adverse effects*; D005665:Furosemide / Q000009:adverse effects*; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology*; D016030:Kidney Transplantation; D008297:Male; D011183:Postoperative Complications / Q000209:etiology
D005665:Furosemide; D002216:Captopril
Insuffisance rénale réversible et hypertension artérielle après transplantation rénale: rôle d'une sténose de l'artère du transplant et de l'association captopril-furosémide.