Survival of dissociated adrenal chromaffin cells of rat and monkey transplanted into rat brain.
Adrenal chromaffin cells from adult rats and monkeys were mechanically dissociated and implanted into the striatum of adult rats by stereotaxic injection. Rat chromaffin cells survived (5%) and showed differentiation by forming processes 1 h-28 days after implantation. Monkey chromaffin cells survived for 48 h but showed very little formation of processes. The method presented allows rapid nonenzymatic dissociation and transplantation of adrenal medullary cells.
D000313:Adrenal Medulla / Q000166:cytology / Q000637:transplantation*; D000818:Animals; D001921:Brain / Q000601:surgery; D002143:Callitrichinae; D002454:Cell Differentiation; D002470:Cell Survival; D051381:Rats; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous