Extradural spinal angiolipoma with secretory activity. An ultrastructural, clinico-pathological study.
The light and ultrastructural analyses of an extradural intraspinal angiolipoma causing symptoms of spinal cord compression, are reported. The tumour showed morphological evidence of an endocrine-like secretory activity of fat cells, with an apparent mechanism of secretory function that has not previously been described for angiolipomas. The secretory granules, containing a lipid-like material, were covered with a continuous basement membrane originating from the basement membrane of the adipocyte.
D005089:Exocytosis; D006391:Hemangioma / Q000378:metabolism* / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D008067:Lipoma / Q000378:metabolism* / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D013120:Spinal Cord Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000648:ultrastructure