Continuous acid-base assessment of the human fetus during labour by tissue pH and transcutaneous carbon dioxide monitoring.
Simultaneous monitoring of fetal tissue pH (t-pH) and transcutaneous carbon dioxide (Tc-PCO2) was performed in 30 labours. Both t-pH and Tc-PCO2 at delivery were positively correlated with pH (r = 0.69) and PCO2 (r = 0.68) of the umbilical artery blood. A tissue/transcutaneous standard base excess (t-SBE) was derived from the t-pH and the Tc-PCO2 and calculated for 13 fetuses at delivery; there was a correlation with standard base excess of umbilical artery blood. An analysis of t-pH and Tc-PCO2 changes during the last hour of labour revealed that only infants who were born with decreased pH of the umbilical artery blood had decreasing t-SBE, while all others had a constant t-SBE.
D000136:Acid-Base Equilibrium; D001784:Blood Gas Analysis; D002245:Carbon Dioxide / Q000032:analysis*; D005260:Female; D005318:Fetal Heart / Q000502:physiology; D005323:Fetal Monitoring / Q000379:methods*; D005333:Fetus / Q000378:metabolism; D006339:Heart Rate; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007743:Labor, Obstetric; D011247:Pregnancy; D014469:Umbilical Arteries / Q000378:metabolism
D002245:Carbon Dioxide