The medullary cardiovascular effects of imidazolines and some GABA analogues: a review.
A study of the localizations and mechanisms of the hypotensive action of clonidine-like substances and GABA analogues. It is confirmed that these agents act on the ventral surface of the medulla oblongata and are involved in the central control of the cardiovascular system. Suggestions are offered relative to the development of new centrally acting antihypertensive agents.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D002415:Cats; D007093:Imidazoles / Q000494:pharmacology*; D008526:Medulla Oblongata / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000494:pharmacology
D007093:Imidazoles; D005680:gamma-Aminobutyric Acid