[Effect of mutations damaging cyclic adenosine-3',5'-monophosphate receptor protein on the expression of catabolic operons in Escherichia coli delta ptsH K12].
Effectivity of expression of catabolite operons is repressed in bacteria with altered cytoplasmic components of the sugar, transport system (pts mutants). Mutation crp* changing the ability of the cyclic adenosine-3',5'-monophosphate receptor protein to activate transcription leads to suppression of the pts mediated disturbance of the enzyme inducible synthesis. This suppression manifests in ability of double delta ptsH crp* mutants to utilize different substrates and in restoration of the rate of beta-galactosidase synthesis and L-tryptophanase synthesis up to the levels in wild type bacteria.
D004926:Escherichia coli / Q000235:genetics* / Q000378:metabolism; D005786:Gene Expression Regulation; D005798:Genes, Bacterial; D009154:Mutation; D009876:Operon; D011953:Receptors, Cyclic AMP / Q000235:genetics*
D011953:Receptors, Cyclic AMP
Vliianie mutatsiĭ, povrezhdaiushchikh belok-retseptor tsiklicheskogo adenozin-3',5'-monofosfata, na ékspressiiu katabolitnykh operonov u bakteriĭ delta ptsH Escherichia coli K12.