Arachidonate lipoxygenase activity modulating factors in human plasma and amniotic fluid.
A radiometric method has been established that permits evaluation of the potential of substances to act as modulators of arachidonate lipoxygenase activity. Using this method it has been found that human plasma and amniotic fluid contain substances that are inhibitory and stimulatory of arachidonate lipoxygenase activity.
D000653:Amniotic Fluid / Q000201:enzymology*; D001091:Arachidonate Lipoxygenases; D005260:Female; D006801:Humans; D006893:Hydroxyeicosatetraenoic Acids / Q000096:biosynthesis; D008084:Lipoxygenase / Q000097:blood / Q000378:metabolism*; D016859:Lipoxygenase Inhibitors; D011247:Pregnancy
D006893:Hydroxyeicosatetraenoic Acids; D016859:Lipoxygenase Inhibitors; C025984:15-hydroxy-5,8,11,13-eicosatetraenoic acid; D001091:Arachidonate Lipoxygenases; D008084:Lipoxygenase