Efficacy of iron therapy: a comparative evaluation of four iron preparations administered to anaemic pregnant women.
The authors conducted a clinical investigation on sixty-nine pregnant women, anaemic and non-anaemic, the purpose being to assess the effect of 50 days treatment with four different medicinal iron preparations, namely, ferrous sulphate, iron chondroitinsulfuric acid complex, and ferritin alone or associated with folinic acid and cobamamide, on various haematological parameters (Hb, RCC, Ht, CV, Iron, and Transferrin IBC). The four products demonstrated a similar efficacy in maintaining anaemic conditions under control; moreover, the results confirmed our hypothesis of the absorption of iron ferritin. While three products were well tolerated, ferrous sulphate induced, in some cases, side-effects.
D000328:Adult; D000747:Anemia, Hypochromic / Q000188:drug therapy*; D002807:Chondroitin / Q000031:analogs & derivatives*; D002809:Chondroitin Sulfates / Q000627:therapeutic use*; D003038:Cobamides / Q000627:therapeutic use; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D004906:Erythrocyte Count; D004909:Erythrocyte Indices; D005260:Female; D005293:Ferritins / Q000627:therapeutic use*; D005296:Ferrous Compounds / Q000627:therapeutic use*; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000097:blood / Q000627:therapeutic use*; D002955:Leucovorin / Q000627:therapeutic use; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011897:Random Allocation; D014168:Transferrin / Q000378:metabolism
D003038:Cobamides; D004338:Drug Combinations; D005296:Ferrous Compounds; D006454:Hemoglobins; D014168:Transferrin; D002807:Chondroitin; D002809:Chondroitin Sulfates; D005293:Ferritins; D007501:Iron; C000913:cobamamide; D002955:Leucovorin