[Analysis of the modifying effect of testosterone on postradiation changes in spermatogenesis].
Cytological analysis showed that disturbances referable to division and development of spermatogonia (intermediate and B types) and primary spermatocytes in irradiated animals are modified by injection of exogenous testosterone. It was established that the hormone exerts its modifying effect after radiation doses affecting mechanisms of spermatogenesis regulation. Testosterone bound to target cells initiates their division and decreases duration of spermatogonium mitosis block and delay in primary spermatocyte development increasing the number of germ cells.
D000818:Animals; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D008297:Male; D051379:Mice; D013091:Spermatogenesis / Q000187:drug effects / Q000528:radiation effects*; D013739:Testosterone / Q000494:pharmacology*; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes; D013739:Testosterone
Analiz modifitsiruiushchego deĭstviia testosterona na postluchevye izmeneniia spermatogeneza.