[8 cases of drug-resistant Plasmodium falciparum malaria contracted in Mozambique].
Between April and June 1984, eight chloroquine-resistant P. falciparum malaria cases were observed in non-immune patients after their emergency sanitary return from NE Mozambique. In vivo resistance to amodiaquine and pyrimethamine were demonstrated from two isolates. Radical cure was obtained with mefloquine in all cases. These patients came from an expatriate community of 35 adult men among which six other chloroquine-resistant malarial cases were probable. The epidemic pattern of this chloroquine-resistant focus is underlined.
D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use; D002738:Chloroquine / Q000627:therapeutic use*; D004351:Drug Resistance; D006801:Humans; D008288:Malaria / Q000188:drug therapy / Q000517:prevention & control*; D008297:Male; D015767:Mefloquine; D009073:Mozambique; D010963:Plasmodium falciparum / Q000187:drug effects*; D011804:Quinolines / Q000627:therapeutic use
D000962:Antimalarials; D011804:Quinolines; D002738:Chloroquine; D015767:Mefloquine
Huit observations de paludisme à Plasmodium falciparum chimio-résistant contracté au Mozambique.