Establishment of a new human lymphoma line that secretes plasminogen activator.
A new cell line, designated RC-K8, was established from the peritoneal effusion of a patient with histiocytic lymphoma. The RC-K8 had human male karyotype with 14q+ and was found to have B-cell (B1) and monocyte/macrophage (intracytoplasmic alpha subunit of S-100 protein) markers. A fibrin plate method demonstrated that RC-K8 cells release plasminogen activator in culture.
D002460:Cell Line; D006801:Humans; D007621:Karyotyping; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010960:Plasminogen Activators / Q000378:metabolism*
D010960:Plasminogen Activators