[Induction of slow membrane potential oscillations and burst activity in neuron PPa1 of Helix pomatia by a calcium ionophore and serotonin].
The nonbursting pattern of activity of the neuron RPa1 in preparations from dormant snails Helix lucorum was reversibly transformed into the bursting one by addition of Ca-ionophore A23187 (10(-6)-10(-5) M) or serotonin (10(-5)-10(-4) M) into the saline. The slow waves underlying bursts disappeared in presence of quinine (10(-4) M) thus suggesting involvement of Ca-dependent K-conductance in the mechanism of burst generation.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000001:Calcimycin / Q000494:pharmacology*; D002118:Calcium / Q000502:physiology; D005724:Ganglia / Q000166:cytology*; D006372:Helix, Snails; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects*; D009474:Neurons / Q000502:physiology; D011188:Potassium / Q000502:physiology; D011803:Quinine / Q000502:physiology; D012701:Serotonin / Q000494:pharmacology*
D012701:Serotonin; D000001:Calcimycin; D011803:Quinine; D011188:Potassium; D002118:Calcium
Induktsiia medlennykh voln membrannogo potentsiala i pachechnoĭ aktivnosti neĭrona PPa1 vinogradnoĭ ulitki kal'tsievym ionoforom i serotoninom.