Hepatitis B virus DNA in saliva, urine, and seminal fluid of carriers of hepatitis B e antigen.
Concentrated samples of saliva, urine, and seminal fluid from 23 men with chronic liver disease who were positive for hepatitis B e antigen were examined for the presence of hepatitis B virus deoxyribonucleic acid (HBV-DNA) by molecular hybridisation. HBV-DNA was detected in saliva from 15 of 17 men (88%), urine from 12 of 22 men (55%), and seminal fluid from 13 of 21 men (62%). The presence of hepatitis B virus in such secretions has important epidemiological implications for heterosexual and homosexual contact.
D001345:Autoradiography; D002908:Chronic Disease; D004279:DNA, Viral / Q000032:analysis* / Q000652:urine; D006511:Hepatitis B Antigens / Q000032:analysis*; D006513:Hepatitis B e Antigens / Q000032:analysis*; D006515:Hepatitis B virus; D006525:Hepatitis, Viral, Human / Q000276:immunology / Q000378:metabolism* / Q000652:urine; D006801:Humans; D008297:Male; D012463:Saliva / Q000032:analysis; D012661:Semen / Q000032:analysis
D004279:DNA, Viral; D006511:Hepatitis B Antigens; D006513:Hepatitis B e Antigens