A critical review of the literature on acrolein toxicity.
A detailed literature review of human and animal toxicity studies of acrolein is presented, and information gaps identified that call for further investigation. Specific recommendations are suggested for additional short-/long-term studies, including chemical disposition and cytogenetic investigations. Two bibliographies are provided indicating the scope of the review: (1) literature actually cited and (2) literature examined but not included.
D000171:Acrolein / Q000009:adverse effects / Q000378:metabolism / Q000633:toxicity*; D000395:Air Pollutants, Occupational / Q000633:toxicity; D000447:Aldehydes / Q000633:toxicity*; D000818:Animals; D001711:Biotransformation; D002273:Carcinogens; D002319:Cardiovascular System / Q000187:drug effects; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D002869:Chromosome Aberrations / Q000187:drug effects; D004785:Environmental Pollutants / Q000633:toxicity; D005128:Eye Diseases / Q000139:chemically induced; D006801:Humans; D007408:Intestinal Absorption; D007674:Kidney Diseases / Q000139:chemically induced; D012140:Respiratory Tract Diseases / Q000139:chemically induced; D013723:Teratogens; D014874:Water Pollutants, Chemical / Q000633:toxicity
D000395:Air Pollutants, Occupational; D000447:Aldehydes; D002273:Carcinogens; D004785:Environmental Pollutants; D013723:Teratogens; D014874:Water Pollutants, Chemical; D000171:Acrolein