Design of prodrugs for improved gastrointestinal absorption by intestinal enzyme targeting.
D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D001682:Biological Availability; D002462:Cell Membrane / Q000201:enzymology; D003692:Delayed-Action Preparations; D004285:Dogs; D004304:Dosage Forms; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000201:enzymology; D007421:Intestine, Small / Q000201:enzymology*; D007700:Kinetics; D051379:Mice; D010447:Peptide Hydrolases / Q000378:metabolism*; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D051381:Rats; D013379:Substrate Specificity
D003692:Delayed-Action Preparations; D004304:Dosage Forms; D004364:Pharmaceutical Preparations; D000469:Alkaline Phosphatase; D010447:Peptide Hydrolases