[Comparative sensitivity of 207 strains of strict anaerobic bacteria to piperacillin and 4 other antibiotics].
The MIC of two hundred and seven anaerobic bacterial strains was determined by an agar dilution method for five antibiotics (piperacillin, ampicillin, carbenicillin, cefalotin, metronidazole). 100% of the strains were susceptible to carbenicillin (MIC less than or equal to 128 mg/l), 97% to piperacillin (MIC less than or equal to 16), 86% to metronidazole (MIC less than or equal to 4), 70% to ampicillin (MIC less than or equal to 4) and 68% to cefalotin (MIC less than or equal to 8). Amongst bêta-lactam compounds, piperacillin and ampicillin determined the lowest MIC for Bacteroides fragilis, Fusobacterium, Clostridium and Gram-positive cocci. Amongst Bacteroides fragilis strains, the lowest MIC were obtained with metronidazole.
D000667:Ampicillin / Q000494:pharmacology; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D002228:Carbenicillin / Q000494:pharmacology; D002512:Cephalothin / Q000494:pharmacology; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010878:Piperacillin / Q000494:pharmacology*
D008795:Metronidazole; D000667:Ampicillin; D002228:Carbenicillin; D002512:Cephalothin; D010878:Piperacillin
Sensibilité comparée de deux cent-sept souches de bacteries anaérobies strictes à la pepéracilline et à quatre autres antibiotiques.