Microbial side-chain degradation of sterols.
Apart from the broadly used diosgenin and some further natural compounds sterols gained an increasing importance as raw material for the synthesis of steroid drugs. Parallel to the elucidation of the pathways of the enzymatic degradation of sterols technical processes were developed for a specific degradation of the side-chain to useful primary products. A review is given on the present state of this field and the trends to further improvements.
D001419:Bacteria / Q000378:metabolism*; D005658:Fungi / Q000378:metabolism*; D009615:Nocardia / Q000378:metabolism; D013256:Steroids / Q000096:biosynthesis; D013261:Sterols / Q000378:metabolism*
D013256:Steroids; D013261:Sterols