Amyloid P component in normal human placentae.
The presence of tissue amyloid P component was determined by using a direct immunofluorescence technique on frozen sections of normal human placentae and umbilical cords from gestations of various durations. Amyloid P component was first detected at the 16th week of gestation and appeared to increase progressively in amount so as to be present in abundance in the term placenta. Placental amyloid P component was present in the perifetal capillary zone where basement membrane-like material and reticulin fibres are also found. Amyloid P component may be related to the maturation of the placenta.
D000682:Amyloid / Q000378:metabolism*; D001485:Basement Membrane / Q000378:metabolism; D005260:Female; D005455:Fluorescent Antibody Technique; D005865:Gestational Age; D006801:Humans; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D000683:Serum Amyloid P-Component; D014470:Umbilical Cord / Q000378:metabolism
D000682:Amyloid; D000683:Serum Amyloid P-Component