Hyperreninemic hypertension secondary to radiation nephritis in a child.
Radiation injury to the kidney, first reported almost eighty years ago, may vary from subclinical changes in renal blood flow or enzyme activity to clinically significant hypertension and/or renal failure. A child with radiation-induced hyperreninemic hypertension was cured by nephrectomy. The microscopic, subclinical, and clinical changes of irradiation injury are reviewed. The etiology of radiation-induced hypertension, methods of radioprotection, and early detection of radiation renal damage are discussed.
D002648:Child; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D007668:Kidney / Q000473:pathology / Q000528:radiation effects; D008297:Male; D009392:Nephrectomy; D009393:Nephritis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D011832:Radiation Injuries / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D011878:Radiotherapy / Q000009:adverse effects; D012083:Renin / Q000097:blood*
D012083:Renin