Endocrinological evaluation in a case of XX male syndrome.
A case of a phenotype male with 44 XX karyotype is presented. Clinical, endocrinological and anatomical findings are recorded. Serum level of FSH was elevated, LH level was normal and testosterone level was low. A subnormal response by testicular Leydig cells to hCG was observed. A dexamethasone suppression test and an ACTH test were normal. A B scan ultrasonographic examination did not show female internal genitalia, nor a hyperplasia of adrenal tissue. A review is made of the literature with theories of etiology.
D019326:17-alpha-Hydroxyprogesterone; D000328:Adult; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006908:Hydroxyprogesterones / Q000097:blood; D007621:Karyotyping; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010641:Phenotype; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D012729:Sex Chromosome Aberrations / Q000097:blood*; D013739:Testosterone / Q000097:blood
D006908:Hydroxyprogesterones; D013739:Testosterone; D011374:Progesterone; D019326:17-alpha-Hydroxyprogesterone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D006854:Hydrocortisone