[Acute abdomen with irreversible shock, a rare but typical complication of hemochromatosis].
Acute abdomen, irreversible shock and sudden death are a typical although infrequent complication in patients with hemochromatosis. The author presents a further case of this syndrome and discusses the two leading pathogenetic interpretations described in the literature: sudden release of ferritin, and endotoxin shock. Clinical and post-mortem findings from this patient and a review of 19 cases from the literature suggest that most patients with this syndrome die from a primary bacterial peritonitis with gram negative sepsis and endotoxin shock.
D000006:Abdomen, Acute / Q000150:complications*; D004731:Endotoxins; D004927:Escherichia coli Infections / Q000150:complications; D005260:Female; D006432:Hemochromatosis / Q000150:complications* / Q000235:genetics; D006474:Hemorrhagic Disorders / Q000150:complications; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008875:Middle Aged; D018805:Sepsis / Q000150:complications; D012772:Shock, Septic / Q000150:complications*
D004731:Endotoxins
Akutes Abdomen mit unbeherrschbarem Schock, eine seltene, aber typische Komplikation der Hämochromatose.