Renal effects of acute exposure to toluene. A controlled clinical trial.
Urinary excretion rates of beta 2-microglobulin and albumin were measured in 43 male printing trade workers and 43 age-matched male controls before and during exposure to toluene, 382 mg/m3, for 6 1/2 hours in a climate chamber. There were no significant changes in renal excretion rates of albumin and beta 2-microglobulin during toluene exposure indicating that no causal relationship exists between moderate exposure to organic solvents and renal injury.
D000328:Adult; D000419:Albuminuria; D002986:Clinical Trials as Topic; D003404:Creatinine / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011327:Printing; D014050:Toluene / Q000633:toxicity*; D001613:beta 2-Microglobulin / Q000652:urine
D001613:beta 2-Microglobulin; D014050:Toluene; D003404:Creatinine