[Value of the detection of myoglobin by immunoagglutination in myocardial infarction].
The abnormally elevated quantity of myoglobin present in the plasma of 11 patients suffering of myocardial infarction was demonstrated by a rapid immunoagglutination slide-test. The results of this qualitative test were compared to the myoglobin concentrations measured by radioimmunology. Although the immunoagglutination test is less sensitive than the myoglobin assay, it proved to be very specific. Its rapidity of use, its reliability shown on 121 plasma specimens collected during the myocardial infarction evolution in the patients under study, will enable the clinician to use advantageously the very rapid myoglobinemia taking place in the first hours of infarction. Indeed, we have shown in agreement with the literature that the rise of myoglobin during the first hours of infarction occurs at a much earlier stage than does the increase of creatine kinase activity which was equally assayed during this work.
D000372:Agglutination Tests; D003402:Creatine Kinase / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D009203:Myocardial Infarction / Q000097:blood*; D009211:Myoglobin / Q000097:blood*; D011863:Radioimmunoassay
D009211:Myoglobin; D003402:Creatine Kinase
Intérêt de la détection de la myoglobine par immunoagglutination au cours de l'infarctus du myocarde.