[Treatment with halofantrine of Plasmodium falciparum malaria imported into France].
Halofantrine is a 9-phenanthrene-methanol effective against multiresistant strains of Plasmodium falciparum. It is extremely effective and well-tolerated in treating cases of malaria imported into France. 1,500 mg in 3 doses at 8 hour intervals produced 100% cure rate in semi-immune patients. This dosage could be repeated after 14 days in order to obtain the same cure rate in non-immune patients. Side-effects are minor and include epigastric pain, nausea and one case of skin rash.
D000328:Adult; D000354:Africa, Western; D000962:Antimalarials / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005602:France / Q000208:ethnology; D006801:Humans; D008288:Malaria / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010616:Phenanthrenes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D010963:Plasmodium falciparum; D014195:Travel
D000962:Antimalarials; D010616:Phenanthrenes; C023768:halofantrine
Traitement par l'halofantrine du paludisme à Plasmodium falciparum importé en France.