Coexistence of stomach cancer and renal adenoma in renal allograft. Clinical and autopsy findings and a review of previous cases in Japan.
Autopsy findings of a 34-year-old Japanese male with stomach cancer in a renal allograft are presented. The renal graft was given by his 53-year-old mother, who had the same HLA type as the patient and showed negative response in the Mixed Leukocyte Culture Reaction test. Stomach cancer occurred 4 years and 5 months after the renal graft, and infiltrated widely into the abdominal cavity, causing rectal stricture. In his original left kidney, a small renal adenoma was found. The tumor cells of the adenoma were composed of clear cells. In the adenoma, infiltration of stomach cancer was found. The renal allograft functioned very well until his death in spite of several rejection episodes. This is the seventh reported case in Japan in which a renal allotransplant was accompanied by malignancies.
D000236:Adenoma / Q000150:complications* / Q000473:pathology; D000328:Adult; D002277:Carcinoma / Q000150:complications* / Q000473:pathology; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000473:pathology; D016030:Kidney Transplantation; D008297:Male; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology