Clinicopathologic studies of keratoplasty eyes obtained surgically.
Seventy-two keratoplasty eyes obtained surgically from 72 patients were examined histopathologically. The age at the time of enucleation ranged between 2 months and 91 years, with an average of 47.2 years. The 72 eyes were placed in five categories according to the surgical procedures performed: (a) 20 eyes with a penetrating keratoplasty as the only intraocular operation; (b) nine eyes with two or more penetrating keratoplasties; (c) 29 eyes with one or more keratoplasties with other procedures performed at the same time or another time; (d) nine eyes with lamellar keratoplasties; (e) five eyes with tectonic keratoplasties. The corneas were perforated at the time of keratoplasty in 15 eyes (20.8%). The average age at the first keratoplasty was 45.1 years. Overall, the most frequent causes of enucleation were secondary glaucoma (45.8%), melting of the graft (13.9%), exogenous endophthalmitis (12.5%), and trauma (8.3%). An expulsive hemorrhage occurred in 5.6% of eyes.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D003316:Corneal Diseases / Q000601:surgery; D016039:Corneal Transplantation; D009877:Endophthalmitis / Q000601:surgery; D005128:Eye Diseases / Q000209:etiology / Q000601:surgery; D005260:Female; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D007223:Infant; D007634:Keratitis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures; D011183:Postoperative Complications