Influence of preoperative parenteral alimentation on postoperative growth in adolescent Crohn's disease.
The postoperative growth rates achieved in eight early pubertal adolescent males with Crohn's disease undergoing surgery for obstructive complications is reported as a function of the use of 1 month's preoperative central venous alimentation. All patients had ileal strictures with ileocolitis, bone ages less than 13, Tanner stages 1 or 2, and growth velocities below the 3rd percentile for age. During a 3-year follow-up, those receiving preoperative venous alimentation demonstrated greater oral caloric intake (significant for 1 year) and greater postoperative growth velocity (significant for 2 years) in comparison to those patients who did not receive preoperative venous alimentation. There was no significant difference between the two groups of patients in postoperative weight gain, sexual development, and 3-year disease control.
D000293:Adolescent; D000365:Age Determination by Skeleton; D001835:Body Weight; D003424:Crohn Disease / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D002149:Energy Intake; D005500:Follow-Up Studies; D006128:Growth; D006801:Humans; D008297:Male; D010288:Parenteral Nutrition; D011184:Postoperative Period; D011241:Prednisone / Q000627:therapeutic use; D011300:Preoperative Care; D012741:Sexual Maturation; D013997:Time Factors
D011241:Prednisone