Orthostatic response of plasma renin activity and urinary kallikrein excretion in children with difficulty awakening in the morning.
Twenty-six children, aged 10-15 years, with difficulty awakening in the morning, showed significantly lower plasma renin activity (PRA) before and after standing (15 and 60 min) and significantly greater postural fall in mean blood pressure than the age-matched control children. They also showed high urinary kallikrein excretion, but this was not statistically significant. These results suggest that low PRA and a readily decreasing blood pressure may contribute to difficulty awakening in the morning in teen-aged children.
D000293:Adolescent; D001794:Blood Pressure; D002648:Child; D006339:Heart Rate; D006801:Humans; D007610:Kallikreins / Q000652:urine*; D012083:Renin / Q000097:blood*; D012893:Sleep Wake Disorders / Q000503:physiopathology*; D014851:Wakefulness / Q000502:physiology*
D007610:Kallikreins; D012083:Renin