[Potentials for curing cervical cancer patients with metastases to the regional lymph nodes of the pelvis].
The paper deals with the results of a clinical evaluation of various treatment modalities employed in 155 cases of primary cancer of the uterine cervix (T2 and T3) who had lymphographic signs of metastases into pelvic lymph nodes (N1). The distribution of patients was as follows: group 1--complex gamma-therapy (55 cases), group 2--complex gamma-therapy plus iliac lymphadenectomy (50 cases) and group 3--complex radiation treatment with megavolt bremsstrahlung beam from the luć type installation and iliac lymphadenectomy (50 cases). Five-year survival rates in study groups 1 and 2 were 34,5 and 46.0%, respectively. In 21 cases of group 2 (42.0%), lymphogenic metastasis appeared to be resistant to ionizing irradiation and persisted following complex gamma-therapy. This was confirmed morphologically. Out of these cases, 9 survived for 5 years and were free from recurrence which pointed to the effectiveness of lymphadenectomy. In group 3, histological examination of removed nodes showed that ionizing irradiation had failed to arrest lymphogenic metastasis in 6 cases (12.0%) only. The end results of treatment (62% of 3-year survival) improved significantly due to improvement made at all stages of irradiation as well as combined use of radiation and surgery.
D003131:Combined Modality Therapy; D005260:Female; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008220:Lymphography; D009367:Neoplasm Staging; D010386:Pelvic Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy*
Vozmozhnosti izlecheniia bol'nykh rakom sheĭki matki s metastazami v regionarnye limfaticheskie uzly taza.