The mast cell and bone.
The mast cell, which contains many potent bioactive substances, by its very location must have an effect on bone metabolism in health and disease. In this article, the early questions about mast cells in bone raised by Urist and McLean almost thirty years ago are only partially answered, but the work continues to stimulate new experimental and clinical research on the function of mast cells.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D001854:Bone Marrow Cells; D001862:Bone Resorption; D001842:Bone and Bones / Q000378:metabolism* / Q000473:pathology; D003594:Cytoplasmic Granules / Q000378:metabolism; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications / Q000473:pathology; D008407:Mast Cells / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D008593:Menopause; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D011859:Radiography; D051381:Rats; D014582:Urticaria Pigmentosa / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology