Thymoma with immunodeficiency (Good's syndrome) associated with myasthenia gravis and benign IgG gammopathy.
We treated a case of thymoma with immunodeficiency (Good's syndrome) associated with a rare combination of other parathymic syndromes including myasthenia gravis, benign IgG lambda M component, pernicious anemia, and diabetes. The characterization of the patient's immunologic capacity disclosed practically normal T-cell number and mitogenic responses but impaired lymphokine production as well as B-cell function.
D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications* / Q000276:immunology; D007074:Immunoglobulin G / Q000032:analysis*; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000276:immunology; D007958:Leukocyte Count; D007961:Leukocyte Migration-Inhibitory Factors / Q000096:biosynthesis; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000276:immunology; D013577:Syndrome; D013934:Thymectomy; D013945:Thymoma / Q000150:complications* / Q000276:immunology; D013953:Thymus Neoplasms / Q000150:complications* / Q000276:immunology
D007074:Immunoglobulin G; D007961:Leukocyte Migration-Inhibitory Factors