[Evaluation of the nonspecific resistance of diffuse peritonitis patients by using a lysosomal-cation test and indices of leukocyte phagocytic activity].
Non-specific resistance (NSR) of patients with widespread peritonitis was studied during various stages of the disease: the lysosomal-cation test (LCT) and indexes of phagocytic activity of leucocytes (PAL) were used for the assessment of NSR. The peritonitis stages were determined clinically and by morphological examination of peritoneum biopsies removed during the operation. Different dynamics of LCT and PAL in the patients' blood is revealed depending on the disease stage and clinical postoperative course. LCT is shown to be moderately reduced in the reactive stage, it is progressively decreasing during toxic and terminal stages of the disease. LCT increase and PAL decrease in the postoperative period are characteristic of the benign course of the disease. Negative dynamics of LCT and PAL is noted in patients with a grave course of peritonitis and in cases of postoperative complications. The authors believe that LCT in conjunction with PAL may be used in clinics for the disease prognosis and assessment of the therapy efficiency.
D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D007158:Immunologic Techniques; D007962:Leukocytes / Q000276:immunology*; D008247:Lysosomes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D010537:Peritoneum / Q000473:pathology; D010538:Peritonitis / Q000276:immunology* / Q000473:pathology; D010587:Phagocytosis; D011379:Prognosis
Otsenka nespetsificheskoĭ rezistentnosti bol'nykh razlitym peritonitom s pomoshch'iu lizosomal'no-kationnogo testa i pokazateleĭ fagotsitarnoĭ aktivnosti leĭkotsitov.