Effects of hypothyroidism on the DNA, carbohydrate, soluble protein and sialic acid contents of rat submandibular glands.
Submandibular glands are a target organ of thyroid hormones. This study examined the effects of hypothyroidism on the biochemical characteristics of these glands in the rat. There were no effects on the neutral sugar and DNA contents. However, soluble protein concentrations (micrograms/mg wet weight) were significantly decreased and sialic acid concentrations micrograms/mg soluble protein) were significantly elevated.
D000818:Animals; D050260:Carbohydrate Metabolism; D004247:DNA / Q000378:metabolism; D005260:Female; D007037:Hypothyroidism / Q000097:blood / Q000378:metabolism*; D019158:N-Acetylneuraminic Acid; D011506:Proteins / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012794:Sialic Acids / Q000378:metabolism; D013363:Submandibular Gland / Q000378:metabolism*; D013963:Thyroid Hormones / Q000097:blood
D011506:Proteins; D012794:Sialic Acids; D013963:Thyroid Hormones; D004247:DNA; D019158:N-Acetylneuraminic Acid