Localization of gamma-aminobutyric acid and glutamic acid decarboxylase in rhesus monkey retina.
Use of antisera directed against gamma-aminobutyric acid (GABA) and L-glutamic acid decarboxylase (GAD) in the retina of rhesus monkey reveals immunoreactivity in about one-third of amacrine and horizontal cells and in a subclass of cells situated within the ganglion cell layer. Within the inner plexiform layer neuronal processes form 3 heavily immunoreactive bands which alternate with two lightly reactive bands. Further, a dense narrow band of staining was observed in the scleral half of the outer plexiform layer. Müller cells and their processes are stained with anti-GABA but not with anti-GAD, suggesting that these glial cells take up, but do not synthesize GABA.
D000818:Animals; D005968:Glutamate Decarboxylase / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D008253:Macaca mulatta; D009474:Neurons / Q000378:metabolism; D012160:Retina / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase