[Hormone therapy in progressive and recurrent ovarian cancer].
Estrogen receptors are detectable in an average of 64.5%, progesterone receptors in 49.7% of patients with ovarian carcinoma. But these receptors can also be found in normal ovarian tissue. Response rates of hormonal therapies between 0 and 38% are found in 8 published papers. This corresponds to a mean response rate of 16.5%. Remission rates of 4 to 15% are to be expected under high-dose gestagen therapy. It would seem that hormonal drugs should be applied to improve the general condition and due to psychological reasons.
D004965:Estrogen Antagonists / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D010051:Ovarian Neoplasms / Q000032:analysis / Q000188:drug therapy*; D045167:Progesterone Congeners / Q000627:therapeutic use*; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis
D004965:Estrogen Antagonists; D045167:Progesterone Congeners; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
Hormontherapie bei progredientem und rezidivierendem Ovarialkarzinom.