Intraocular 6-hydroxydopamine prevents the persistent estrus induced by continuous light.
Following the intraocular injection of 6-hydroxydopamine, which can destroy the retinal dopaminergic neurons, female rats showed a normal estrous cycle in LD 12:12 but not a persistent estrus in continuous light.
D000818:Animals; D004298:Dopamine / Q000502:physiology; D004971:Estrus / Q000187:drug effects / Q000528:radiation effects*; D005260:Female; D006892:Hydroxydopamines / Q000008:administration & dosage / Q000494:pharmacology*; D008027:Light; D009043:Motor Activity / Q000187:drug effects / Q000528:radiation effects; D016627:Oxidopamine; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000187:drug effects / Q000502:physiology*
D006892:Hydroxydopamines; D016627:Oxidopamine; D004298:Dopamine