[Effect of beta-adrenergic blockaders and trental on plasma levels of renin and aldosterone in healthy persons during antiorthostatic hypokinesia].
Plasma renin activity and aldosterone levels were measured radioimmunologically in 30 normal individuals subjected to antiorthostatic hypokinesia (at a - 15 degrees angle). Hormonal effects of some drugs (beta-blockers, trental, venotonics) were examined. The short-term antiorthostatic position was associated with a disordered hormonal control, reduced plasma aldosterone and enhanced plasma renin activity, as compared to the respective parameters of the reclining position. The use of beta-adreno-blockers alone or in combinations with other drugs decreases plasma renin activity in conditions of antiorthostatic hypokinesia which can be related to the inhibition of beta-adrenergic activity.
D000328:Adult; D000450:Aldosterone / Q000097:blood*; D006801:Humans; D007103:Immobilization; D008297:Male; D010431:Pentoxifylline / Q000494:pharmacology*; D011187:Posture; D011433:Propranolol / Q000494:pharmacology*; D012083:Renin / Q000097:blood*; D013805:Theobromine / Q000031:analogs & derivatives*; D013806:Theophylline / Q000031:analogs & derivatives* / Q000494:pharmacology; D013997:Time Factors
D000450:Aldosterone; D011433:Propranolol; D013806:Theophylline; D012083:Renin; D013805:Theobromine; D010431:Pentoxifylline; C006683:bamifylline
Vliianie beta-adrenergicheskikh blokatorov i trentala na soderzhanie renina i aldosterona v plazme krovi zdorovykh lits v usloviiakh antiortostaticheskoĭ gipokinezii.