Large Cryptococcus neoformans isolated from brain abscess.
Cryptococcus neoformans yeast cells 40 to 60 micron in diameter were seen in an India ink preparation made from a human brain abscess specimen. In culture at 25 degrees C, uniform 5-micron-diameter yeast cells were produced. Inoculation into mice produced yeast cells up to 40 micron in diameter, and brain heart infusion broth culture at 35 degrees C produced yeast cells about 25 micron in diameter. A relationship of yeast cell diameter to incubation temperature is suggested.
D000328:Adult; D001922:Brain Abscess / Q000382:microbiology*; D003453:Cryptococcosis / Q000382:microbiology*; D003454:Cryptococcus / Q000166:cytology / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008828:Microbiological Techniques; D013696:Temperature