Combined heart-lung transplantation for terminal pulmonary lymphangioleiomyomatosis.
Combined heart-lung transplantation with cyclosporine is reported in a 26-year-old patient who presented with end-stage pulmonary lymphangioleiomyomatosis. The operation was successful and the patient's rehabilitation excellent over the first 7 postoperative months. She then developed obliterative bronchiolitis of unknown origin. To our knowledge, this is the first published report of an out-hospital survival after heart-lung transplantation for terminal nonvascular lung disease.
D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D001982:Bronchial Diseases / Q000209:etiology; D003524:Cyclosporins / Q000627:therapeutic use*; D005260:Female; D016027:Heart Transplantation; D016041:Heart-Lung Transplantation; D006801:Humans; D008175:Lung Neoplasms / Q000628:therapy*; D016040:Lung Transplantation; D008203:Lymphangiomyoma / Q000628:therapy*; D008232:Lymphoproliferative Disorders / Q000628:therapy*; D011183:Postoperative Complications; D011241:Prednisone / Q000627:therapeutic use
D003524:Cyclosporins; D001379:Azathioprine; D011241:Prednisone