Monoclonal antibodies to human casein.
Two monoclonal antibodies, LICR-LON-32.2 (32.2) and LICR-LON-14.1 (14.1), are described which react with human casein. 32.2 reacts with human beta-casein and 14.1 with human kappa-casein. 32.2 also reacts with rat band 2 casein and bovine beta-casein, but 14.1 appears to be specific for human kappa-casein. These monoclonal antibodies do not cross-react with other milk proteins.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis / Q000276:immunology*; D000941:Antigens / Q000032:analysis; D001940:Breast / Q000276:immunology; D002364:Caseins / Q000276:immunology*; D002417:Cattle; D005260:Female; D006041:Goats; D006168:Guinea Pigs; D006801:Humans; D007124:Immunoenzyme Techniques; D007774:Lactation; D008565:Membrane Proteins / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008894:Milk Proteins / Q000276:immunology; D018396:Mucin-1; D011247:Pregnancy; D011817:Rabbits; D051381:Rats; D012756:Sheep; D013045:Species Specificity
D000911:Antibodies, Monoclonal; D000941:Antigens; D002364:Caseins; D008565:Membrane Proteins; D008894:Milk Proteins; D018396:Mucin-1