Chemotherapy of advanced mammary adenocarcinoma in 14 cats.
Fourteen cats with advanced mammary adenocarcinoma were treated with doxorubicin HCl and cyclophosphamide. All cats had inoperable or recurrent disease, and 9 cats had metastasis to the thorax. Eleven of the cats were available for long-term evaluation; 3 had complete response to chemotherapy, with survival times of 180, 283, and 344 days; 2 had partial response, with survival times of 45 and 149 days; 2 had stabilization of disease, with survival times of 170 and 182 days; and 4 had no response, with survival times of 4, 47, 67, and 106 days.
D000230:Adenocarcinoma / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D002986:Clinical Trials as Topic; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D008321:Mammary Glands, Animal; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D009369:Neoplasms / Q000188:drug therapy / Q000662:veterinary*
D004317:Doxorubicin; D003520:Cyclophosphamide