Effect of insulin and glucose on feeding behavior.
Four experimental groups of human subjects, in whom plasma glucose and insulin were independently raised or lowered, were tested for perceptions of hunger, taste, bodily state, and food intake. The data showed that hyperinsulinemia, unrelated to change in plasma glucose concentration, resulted in increased hunger, heightened palatability of sucrose or sweetness, and greater food intake.
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D005247:Feeding Behavior / Q000187:drug effects*; D005947:Glucose / Q000494:pharmacology*; D006801:Humans; D006815:Hunger / Q000187:drug effects; D006943:Hyperglycemia / Q000097:blood / Q000503:physiopathology; D007003:Hypoglycemia / Q000097:blood / Q000503:physiopathology; D007328:Insulin / Q000097:blood / Q000494:pharmacology*; D008297:Male; D013649:Taste / Q000187:drug effects
D001786:Blood Glucose; D007328:Insulin; D005947:Glucose