[Anatomo-clinical presentation of graft-versus-host disease treated with cyclosporin A].
Evaluation of the clinical and histological signs of cutaneous graft-versus-host disease present in 7 patients treated with cyclosporin A was based on a follow-up of 100 days after bone marrow transplantation. Early clinical signs consisted of acral erythema with mild to moderate edema. Histologically, the graft-versus-host reaction was moderate but not completely inhibited. As revealed by autoradiography after labeling with tritiated thymidine and uridine, the lymphoid infiltrate had a low rate of proliferation and a normal or enhanced synthetic activity of ribonucleic acid.
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation; D003524:Cyclosporins / Q000627:therapeutic use*; D004890:Erythema / Q000517:prevention & control; D005500:Follow-Up Studies; D006086:Graft vs Host Disease / Q000473:pathology / Q000517:prevention & control*; D006801:Humans; D008875:Middle Aged; D012867:Skin / Q000473:pathology
D003524:Cyclosporins
Présentation anatomo-clinique de la maladie du greffon contre l'hôte traitée par cyclosporine A.