[Synthetic tripeptide miniluliberin and its biological activity].
The effects of the synthetic decapeptide LH-RH and tripeptide mini LH-RH on LH and FSH secretion were compared. Experiments on ovariectomized female rats receiving estradiol benzoate and progesterone showed that i. v. administration of mini LH-RH produced a stimulating effect on the release of gonadotrophins from the hypophysis. The effects of mini LH-RH were incomparable to those of LH-RH.
D000818:Animals; D002369:Castration; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000494:pharmacology; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Sinteticheskiĭ tripeptid miniliuliberin i ego biologicheskaia aktivnost'.