Developmental interactions between the peripheral and central nervous system in Drosophila melanogaster: analysis of the mutant, two-faced.
A genetically complex mutant, two-faced (tfd), which causes the production of extra eye and antennal tissue on the dorsal head cuticle, has been analyzed for connectivity to and projection patterns in the central brain of nerves derived from these extra structures. It has been found that the extra antennal nerves frequently connect to and achieve normal projections in the brain, whereas no convincing connectivity between the nerves from the extra eye tissue and the brain, has been found. This suggests that the mechanisms by which the nerves derived from normal eyes and antennae achieve central connections may differ.
D000818:Animals; D002490:Central Nervous System / Q000196:embryology; D004331:Drosophila melanogaster / Q000235:genetics / Q000254:growth & development*; D005123:Eye / Q000196:embryology / Q000294:innervation; D005786:Gene Expression Regulation; D009154:Mutation; D009420:Nervous System / Q000196:embryology*; D010525:Peripheral Nerves / Q000196:embryology; D010641:Phenotype