Inhibition of exercise-induced asthma by three forms of sodium cromoglycate.
Fifteen asthmatic children were tested in a double-blind fashion. The degree of prevention of exercise-induced asthma by three pharmacological forms of sodium cromoglycate (SCG with lactose powder, SCG in micropellets without lactose and SCG solution) was evaluated. FEV1 and FEF 25-75 were measured. Inhibition of the airway response to exercise was achieved by SCG without any statistical differences between the three active forms. Our data suggest that the new pelletised form of SCG without lactose is as active as the other preparations of the drug. The easy mode of administration allows a high compliance of the young asthmatic patients to chronic therapy.
D000293:Adolescent; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy*; D001250:Asthma, Exercise-Induced / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002214:Capsules; D002648:Child; D004205:Cromolyn Sodium / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D011208:Powders; D012129:Respiratory Function Tests
D000336:Aerosols; D001993:Bronchodilator Agents; D002214:Capsules; D011208:Powders; D004205:Cromolyn Sodium