[Conservative treatment of tumors of the retina at the Curie Institute. Long-term results of 129 cases treated with Stallard's disk and electrons].
The authors report a retrospective study of 129 children with retinoblastoma treated from 1963 to 1977 at the Institut Curie by enucleation of the worst eye and conservative irradiation of the other eye; this irradiation was performed either with Stallard plaque (19 cases) or with electrons (110 cases). In 8 familial cases, no enucleation has been performed. T.E.M. was used from 1964 to 1973 and iterative photocoagulation since 1968. With a 5 years follow up, 88 children (68%) are living NED, 6 are lost. There was 34 treatment failures (26%) and 1 death from second malignant tumor. At 10 and 15 years, the results are stable despite the occurrence of two other second primary tumors. Irradiation preserved 73/94 (78%) of the irradiated eyes. The technical aspects of the radiotherapy with electrons and both ocular and vital prognostic factors are discussed.
D001918:Brachytherapy / Q000295:instrumentation*; D002675:Child, Preschool; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004583:Electrons; D005134:Eye Neoplasms / Q000235:genetics / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008028:Light Coagulation; D008297:Male; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000628:therapy; D011379:Prognosis; D011882:Radiotherapy, High-Energy / Q000379:methods*; D012175:Retinoblastoma / Q000235:genetics / Q000532:radiotherapy* / Q000601:surgery
D003037:Cobalt Radioisotopes
Traitement conservateur des tumeurs de la rétine à l'Institut Curie. Résultats à long terme de 129 cas traités par disque de Stallard et électrons.