[New effective therapy of systemic infection with Nocardia asteroides].
A combination of amoxicillin with clavulanic acid (a beta-lactamase inhibitor) and the aminoglycoside amikacin proved effective in the treatment of advanced pulmonary nocardiosis in a 49-year-old man. The result accorded with preceding in-vitro and animal experiments and justifies this combination of drugs in the treatment of nocardiosis, especially if the causative organism is N. farcinica (N. asteroides, biovariety B).
D000583:Amikacin / Q000627:therapeutic use*; D000658:Amoxicillin / Q000627:therapeutic use*; D001999:Bronchoscopy; D002969:Clavulanic Acids / Q000627:therapeutic use*; D004562:Electrocardiography; D006801:Humans; D007612:Kanamycin / Q000031:analogs & derivatives*; D008168:Lung / Q000382:microbiology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000188:drug therapy*; D009616:Nocardia asteroides
D002969:Clavulanic Acids; D007612:Kanamycin; D000658:Amoxicillin; D000583:Amikacin
Neue erfolgreiche Therapie bei systemischer Infektion mit Nocardia asteroides.