Transient increase of Ca2+ uptake as a signal for mating pheromone-induced differentiation in the heterobasidiomycetous yeast Rhodosporidium toruloides.
The role of Ca2+ for the signaling of rhodotorucine A, a mating pheromone of Rhodosporidium toruloides, was investigated. The efficiency with which the target cells responded to the mating pheromone was dependent on the Ca2+ concentration in the medium. The pheromone induced a very rapid and transient increase of Ca2+ uptake in the recipient cell. We concluded that the transient increase in the intracellular Ca2+ concentration could play an essential role in the control of differentiation by the pheromone.
D000818:Animals; D001487:Basidiomycota / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D002454:Cell Differentiation / Q000187:drug effects; D004533:Egtazic Acid / Q000494:pharmacology; D010675:Pheromones / Q000494:pharmacology*; D012724:Sex Attractants / Q000494:pharmacology*
D010675:Pheromones; D012724:Sex Attractants; D004533:Egtazic Acid; D002118:Calcium