[Localization of basal cell antigen in the epithelial tissues of animals and humans detected by means of natural antibodies].
By means of the immunofluorescent method using rabbit serum that contains natural antibodies against the basal cell antigen of epidermis, the distribution of the antigen has been demonstrated in cells of the basal layer of all types of the stratified epithelium. The reaction is also noted in cytoplasm of the epithelial cells in the thymus and the tracheal mucous membrane. This demonstrates their histogenic affinity to stratified epithelii. The antigen studied is not species-specific, since it is revealed in the stratified epithelium of all species examined (human being, mouse, rat, guinea pig, rabbit). It is possible to use the basal cell antigen as a marker for immunomorphological reveal of epithelial cells in the thymus in the process of its physiological and pathological involution.
D000818:Animals; D000941:Antigens; D004817:Epidermis / Q000276:immunology*; D004848:Epithelium / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D006801:Humans; D051379:Mice; D009928:Organ Specificity; D011817:Rabbits; D051381:Rats
D000941:Antigens
Lokalizatsiia bazal'no-kletochnogo antigena v épitelial'nykh tkaniakh zhivotnykh i cheloveka, vyiavlennaia s pomoshch'iu estestvennykh antitel.