[Glucose reabsorption in the kidneys of rats after insulin administration against a background of stabilized hyperglycemia].
In rat with constant i. v. infusion of 40% glucose solution, administration of insulin (0.9-1.0 unit/100 g) reduced considerably diuresis, filtration and excretion of glucose in urine, the glucose content in the blood remaining the same. The absolute velocity of glucose reabsorption in the kidneys remained the same as in control but, in regard to the glomerular filtration (as per 1 ml), the velocity increased 2-fold. Insulin seems to be able to control glucose reabsorption in the renal tubular cells.
D000042:Absorption; D000818:Animals; D004231:Diuresis; D005260:Female; D005919:Glomerular Filtration Rate; D005947:Glucose / Q000378:metabolism*; D006943:Hyperglycemia / Q000503:physiopathology*; D007328:Insulin; D007687:Kidney Tubules, Proximal / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D007328:Insulin; D005947:Glucose
Reabsorbtsiia gliukozy v pochkakh krys pri vvedenii insulina na fone stabilizirovannoĭ giperglikemii.