The treatment of soft tissue defects with injectable collagen.
Two forms of highly purified bovine dermal collagen (Zyderm I and II Collagen Implant) are currently in widespread clinical use for the treatment of dermal soft tissue defects. These materials, which closely resemble human collagen, are administered via injection in a series of outpatient treatments. With successive injections, small amounts of collagen are deposited to fill areas deficient in soft tissue. A review of the literature indicates that these materials can be used safely and effectively to correct certain scars, age-related wrinkles, areas of steroid atrophy, and small surgical defects.
D000818:Animals; D000906:Antibodies / Q000032:analysis; D000917:Antibody Formation; D002921:Cicatrix / Q000628:therapy; D003094:Collagen / Q000276:immunology / Q000627:therapeutic use*; D006801:Humans; D007267:Injections / Q000379:methods; D013518:Surgery, Plastic
D000906:Antibodies; D003094:Collagen