Hereditary hemorrhagic telangiectasia and factor VIII inhibitor.
A patient with hereditary hemorrhagic telangiectasia manifested recurrent gastrointestinal bleeding aggravated by an acquired factor VIII inhibitor. Immunosuppressive therapy with cyclophosphamide and prednisone successfully corrected the coagulation defect.
D001780:Blood Coagulation Tests; D001803:Blood Transfusion; D003520:Cyclophosphamide / Q000627:therapeutic use; D005169:Factor VIII / Q000032:analysis / Q000037:antagonists & inhibitors*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D011241:Prednisone / Q000627:therapeutic use; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications*
D003520:Cyclophosphamide; D005169:Factor VIII; D011241:Prednisone