Comparability and precision of serum PCB measurements.
The 95% prediction interval for single measurements of serum "Aroclor" reported by a reputable commercial analyst was found to be approximately +/- 42%. The geometric mean serum PCB levels in a population of capacitor workers who had formerly had direct exposure to the commercial PCBs--Aroclors 1016, 1242, and 1254-were found to be alternatively reportable as 1905 ppb minimum initial PCBs (as calculated from most persistent peaks present); 1093 ppb non-overlapping analytical "Aroclor" levels (as calculated by the conventional sum-of-the-peak-heights method); 303 ppb total PCBs actually present; or 19 ppb "human PCB" (as calculated by the NHMP procedure). The broad spread in reportable values was relatable to the PCB isomer distribution and clearance patterns in the occupationally exposed population.
D000328:Adult; D001140:Aroclors / Q000097:blood; D020111:Chlorodiphenyl (54% Chlorine); D002849:Chromatography, Gas; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011078:Polychlorinated Biphenyls / Q000097:blood*
D001140:Aroclors; C026987:aroclor 1260; D020111:Chlorodiphenyl (54% Chlorine); C027386:Aroclor 1016; D003633:Dichlorodiphenyl Dichloroethylene; C027423:aroclor 1242; D011078:Polychlorinated Biphenyls