Comparison of intravenous salbutamol (albuterol) and aminophylline in the treatment of acute asthmatic attacks.
Our investigation supports the use of intravenous salbutamol as an alternative to aminophylline in the early stages of acute severe asthma. Salbutamol proved to be a marginally better bronchodilator and is likely to cause less gastrointestinal side effects than aminophylline, but tachycardia and generalized tremor are more frequent with this drug.
D000420:Albuterol / Q000008:administration & dosage* / Q000009:adverse effects; D000628:Aminophylline / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy*; D002986:Clinical Trials as Topic; D006261:Headache / Q000139:chemically induced; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007275:Injections, Intravenous; D010366:Peak Expiratory Flow Rate; D011674:Pulse / Q000187:drug effects; D011897:Random Allocation; D014202:Tremor / Q000139:chemically induced
D000628:Aminophylline; D000420:Albuterol