Protein variation in clones of Plasmodium falciparum detected by two dimensional electrophoresis.
Two dimensional electrophoresis has been used to examine protein variation in clones of two Plasmodium falciparum isolates. Variant forms of 12 proteins were detected. Five genetically distinct parasite types were identified in one isolate, and two in the second isolate. Examination of uncloned parasites using this technique showed that the frequency of each genotype altered during six months of culture.
D000818:Animals; D002999:Clone Cells; D004591:Electrophoresis, Polyacrylamide Gel; D014644:Genetic Variation; D007525:Isoelectric Focusing; D010641:Phenotype; D010963:Plasmodium falciparum / Q000032:analysis / Q000235:genetics*; D011506:Proteins / Q000032:analysis / Q000235:genetics*; D013785:Thailand
D011506:Proteins