[Comparative immunopathologic study of oral aphthae, non-involved mucosa from aphthae patients, healthy mucosa and trauma-induced ulcers].
The presence of IgG, IgA, IgM, C1q, C3c, fibrinogen and properdin has been studied using direct immunofluorescence technique. The same study has been performed in clinically normal mucosa of patients with aphthous ulcers, normal mucosa of healthy volunteers and traumatically induced ulcers. We have also studied the possible presence of reactive serous immunoglobulins with normal mucosa by indirect immunofluorescence. Our findings do not support previous studies which claimed the presence of vasculitis induced by the presence of immunoreactants in the vessel walls.
D000293:Adolescent; D000328:Adult; D003176:Complement C3 / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology; D013281:Stomatitis, Aphthous / Q000276:immunology* / Q000473:pathology
D003176:Complement C3; D007136:Immunoglobulins
Estudio inmunopatológico comparativo de aftas orales, mucosas no afectas por úlceras de pacientes aftosos, mucosas sanas y úlceras inducidas de forma traumática.