The therapeutic actions of theophylline in preterm ventilated infants.
40 preterm, ventilated infants (gestational ages 24-33 weeks) were entered into a double-blind randomised trial to assess the effect of oral theophylline on lung function and ventilator dependence. Theophylline administration was associated with a significant improvement in compliance (P less than 0.05) and hastened weaning from ventilation (P less than 0.01).
D000284:Administration, Oral; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008170:Lung Compliance; D012121:Respiration, Artificial; D013806:Theophylline / Q000008:administration & dosage / Q000627:therapeutic use*
D013806:Theophylline