Indoprofen--a new non-opioid analgesic. A comparison with pethidine.
Indoprofen (400 mg), a non-opioid, non-steroidal anti-inflammatory drug, was compared on a random, double-blind basis with pethidine (1,5 mg/kg) after elective caesarean section (40 patients) and after orthopaedic surgery (40 patients). The drugs were given intravenously during anaesthesia and provided adequate analgesia for a period of up to 2 hours postoperatively. No significant differences between the two drugs were noted in terms of efficacy and side-effects.
D000293:Adolescent; D000328:Adult; D002585:Cesarean Section; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007216:Indoprofen / Q000627:therapeutic use*; D007432:Intraoperative Period; D008614:Meperidine / Q000627:therapeutic use; D009985:Orthopedics; D010149:Postoperative Pain / Q000188:drug therapy*; D010666:Phenylpropionates / Q000627:therapeutic use*; D011897:Random Allocation
D010666:Phenylpropionates; D008614:Meperidine; D007216:Indoprofen