[Resistance to organic tin compounds mediated by plasmids of bacteria of Pseudomonas genus].
Resistance to organic tin compounds of P. aeruginosa and E. coli carrying antibiotic resistance plasmids and to P. putida containing biodegradation plasmids was studied. It was shown that 5 resistance plasmids and the biodegradation CAM plasmid of Pseudomonas increased 3-4 times the strain resistance to triethylstannylsuccinylimide and triethylstannylmaleinimide. All these plasmids belong to the P-2 incompatibility group and also determine the bacterial resistance to potassium tellurite. Isolation and investigation of the mutant plasmids loosing simultaneously the capacity for determination of resistance to potassium tellurite and organic tin compounds suggest that resistance to these compounds in the investigated plasmids is determined by the same genetic system.
D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D008301:Maleimides / Q000494:pharmacology; D011549:Pseudomonas / Q000187:drug effects / Q000235:genetics*; D011815:R Factors; D013388:Succinimides / Q000494:pharmacology; D013691:Tellurium / Q000494:pharmacology; D014220:Trialkyltin Compounds / Q000494:pharmacology*; D014267:Triethyltin Compounds / Q000494:pharmacology*
D008301:Maleimides; D013388:Succinimides; D014220:Trialkyltin Compounds; D014267:Triethyltin Compounds; C045754:triethylstannylsuccinimide; C026899:potassium tellurate(IV); C046157:triethylstannylmaleimide; D013691:Tellurium
Determiniruemaia plazmidami bakteriĭ roda Pseudomonas ustoĭchivost' k organicheskim soedineniiam olova.