Progesterone treatment of premenstrual tension--a double blind study.
Fifteen women with moderate to severe premenstrual symptoms, defined and graded according to a recently developed scoring system, took part in a double blind study of the effect of progesterone on premenstrual symptoms. The dosage was 100 mg progesterone twice daily delivered in vaginal pessaries. The women were improved with a statistically significant decrease in their scores by progesterone as well as by placebo treatment. There was no statistically significant difference between the two regimes.
D000328:Adult; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D010570:Pessaries; D011293:Premenstrual Syndrome / Q000188:drug therapy*; D011374:Progesterone / Q000008:administration & dosage / Q000627:therapeutic use*; D014621:Vagina
D011374:Progesterone