Pure red cell aplasia characterized by erythropoietic maturation arrest. Response to anti-thymocyte globulin.
Pure red cell aplasia is a syndrome characterized by markedly decreased erythropoiesis. On bone marrow examination, there are typically less than 0.5 percent erythroblasts, but sometimes a picture of maturation arrest can be seen. This report describes a patient with maturation arrest of erythropoiesis at the basophilic normoblast stage who had a response to an eight-day course of anti-thymocyte globulin with a return of normal erythropoiesis.
D000328:Adult; D000961:Antilymphocyte Serum / Q000627:therapeutic use*; D001803:Blood Transfusion; D001853:Bone Marrow / Q000473:pathology; D017707:Erythrocyte Transfusion; D004920:Erythropoiesis; D005260:Female; D005474:Fluoxymesterone / Q000627:therapeutic use; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D012010:Red-Cell Aplasia, Pure / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology*
D000961:Antilymphocyte Serum; D005474:Fluoxymesterone; D011241:Prednisone