[Radiotherapy and combined chemo- and radiotherapy of patients with squamous cell lung cancer (randomized study)].
A randomized study on the results of treatment of 76 cases of squamous cell carcinoma of the lung was conducted at the Center in 1976-1981. Radiation and chemoradiation procedures were studied in two groups of patients. The immediate results of chemoradiation therapy were somewhat better as compared with radiation treatment alone. However, no significant increase in survival rates was recorded. The toxicity of the chemotherapeutic procedures used was shown. Total focal dose was increased to 90-120 Gy and longer survival was registered as a result of consistent application of uneven irradiation and open fields in gamma therapy.
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy*; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D011447:Prospidium / Q000008:administration & dosage; D011879:Radiotherapy Dosage; D011897:Random Allocation; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D011447:Prospidium; D003520:Cyclophosphamide; D008727:Methotrexate
Luchevaia i khimioluchevaia terapiia bol'nykh ploskokletochnym rakom legkogo (randomizirovannoe issledovanie).