[Treatment of gastroparesis by primperan].
The motor action of Primperan on the stomach is discussed. This action causes a significant acceleration in gastric emptying, as a result of an increased contractile activity of the stomach and a duodeno-gastric synergy. The clinical activity of Primperan in diabetic, post-surgical and idiopathic gastroparesis has been confirmed by means of double blind s studies. The daily administration of 40 mg of Primperan, in 4 divided doses before meals and at bedtime, leads to a statistically significant improvement in the gastro-intestinal symptoms of these patients.
D048909:Diabetes Complications; D005746:Gastric Emptying / Q000187:drug effects; D005769:Gastrointestinal Motility / Q000187:drug effects; D006801:Humans; D008787:Metoclopramide / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D013272:Stomach Diseases / Q000188:drug therapy* / Q000209:etiology
D008787:Metoclopramide
Traitement des gastroparésies par le primpéran.