Pathogenesis and treatment of immune-mediated renal disease.
There is now convincing evidence to suggest that most forms of glomerulonephritis and tubulointerstitial nephropathy involve the immune system in the destructive process. Such involvement can be mediated by a humoral immune response, a cell-mediated immune response, or a coordinated response of both limbs of the immune system derived from complementary T- and B-cell interactions.
D000328:Adult; D000936:Antigen-Antibody Complex / Q000502:physiology; D002648:Child; D005920:Glomerular Mesangium / Q000276:immunology / Q000473:pathology; D005921:Glomerulonephritis / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D005923:Glomerulosclerosis, Focal Segmental / Q000188:drug therapy / Q000276:immunology / Q000473:pathology; D006801:Humans; D007111:Immunity, Cellular; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000276:immunology / Q000473:pathology; D009395:Nephritis, Interstitial / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D009402:Nephrosis, Lipoid / Q000209:etiology / Q000276:immunology / Q000473:pathology; D013997:Time Factors
D000936:Antigen-Antibody Complex