Stimulation of DNA synthesis in human fibroblasts by human pancreatic secretory trypsin inhibitor.
Human pancreatic secretory trypsin inhibitor stimulated [3H]thymidine incorporation into DNA in human fibroblasts at concentrations present in human serum. Combined addition of human pancreatic secretory trypsin inhibitor and porcine insulin gave more than additive stimulation of [3H]thymidine incorporation.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002478:Cells, Cultured; D004247:DNA / Q000096:biosynthesis*; D005347:Fibroblasts / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000494:pharmacology; D013268:Stimulation, Chemical; D013552:Swine; D013936:Thymidine / Q000378:metabolism; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000032:analysis / Q000494:pharmacology*; D014361:Trypsin Inhibitors / Q000494:pharmacology*
D000596:Amino Acids; D007328:Insulin; D014361:Trypsin Inhibitors; D014359:Trypsin Inhibitor, Kazal Pancreatic; D004247:DNA; D013936:Thymidine