Oxybutinin and the prevention of urinary incontinence in spina bifida.
A controlled study was performed to determine the effect of oxybutinin on incontinence in spina bifida patients on clean, intermittent self catheterisation. Cure or significant improvement was achieved in 66.6% of the patients. Bladder capacity was increased and filling pressure reduced during treatment.
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000627:therapeutic use*; D010276:Parasympatholytics / Q000627:therapeutic use*; D011446:Prospective Studies; D011897:Random Allocation; D016136:Spina Bifida Occulta / Q000150:complications*; D014546:Urinary Catheterization; D014549:Urinary Incontinence / Q000209:etiology / Q000517:prevention & control*
D008333:Mandelic Acids; D010276:Parasympatholytics; C005419:oxybutynin