[Endonuclease activity with acid and alkaline pH values in rat blood serum during whole body gamma-irradiation].
Using the method of electrophoresis in agar gel of superhelical plasmid DNA, which served as a substrate for determining endonuclease activity, the authors showed that the same radiation dose influenced in a different way the activity of acid and alkaline DNAases in rat blood serum. At early times (3-6 h) following irradiation, the activity of acid nucleases increased whereas that of alkaline DNAases decreased.
D000818:Animals; D003037:Cobalt Radioisotopes; D003851:Deoxyribonucleases / Q000097:blood*; D005720:Gamma Rays; D006863:Hydrogen-Ion Concentration; D008297:Male; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes; D003851:Deoxyribonucleases
Issledovanie éndonukleaznoĭ aktivnosti pri kislom i shchelochnom znacheniiakh pH v syvorotke krovi krys pri obshchem gamma-izluchenii.