Monoclonal antibodies and the skin biopsy: current and potential clinical applications.
Monoclonal antibodies are becoming increasingly useful in the clinical diagnosis and/or treatment of a number of unrelated diseases. Discussion will be directed to those monoclonal antibodies recognizing antigens within the skin which appear to have either proven or potential application in the diagnostic evaluation of the skin biopsy.
D000911:Antibodies, Monoclonal; D000941:Antigens / Q000032:analysis; D000951:Antigens, Neoplasm / Q000276:immunology; D001485:Basement Membrane / Q000276:immunology; D001706:Biopsy; D003094:Collagen / Q000032:analysis; D003872:Dermatitis / Q000175:diagnosis / Q000276:immunology; D003896:Desmosomes / Q000276:immunology; D004820:Epidermolysis Bullosa / Q000175:diagnosis / Q000276:immunology; D000091344:Filaggrin Proteins; D005455:Fluorescent Antibody Technique; D006801:Humans; D007381:Intermediate Filament Proteins / Q000032:analysis; D008545:Melanoma / Q000175:diagnosis / Q000276:immunology; D008854:Microscopy, Electron; D011498:Protein Precursors / Q000032:analysis; D012867:Skin / Q000276:immunology* / Q000473:pathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000276:immunology; D012874:Skin Diseases, Infectious / Q000175:diagnosis / Q000276:immunology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000941:Antigens; D000951:Antigens, Neoplasm; D000091344:Filaggrin Proteins; D007381:Intermediate Filament Proteins; D011498:Protein Precursors; D003094:Collagen