Bactericidal properties of a new water disinfectant.
The N-chloramine compound 3-chloro-4,4-dimethyl-2-oxazolidinone (agent I) has been compared with calcium hypochlorite as to its efficacy as a bactericide for the treatment of water. The study included concentration, contact time, pH, temperature, and water quality as controlled variables. The species of bacteria tested were Staphylococcus aureus, Pseudomonas aeruginosa, and Shigella boydii. In general, for highly pure, demand-free water, calcium hypochlorite was the more rapid disinfectant at a given total chlorine concentration, although for water containing a controlled amount of organic load, agent I was the better disinfectant. The differences in efficacy of each of the two disinfectants can be attributed primarily to their different stabilities in water at various controlled conditions.
D001419:Bacteria / Q000187:drug effects*; D002118:Calcium / Q000494:pharmacology; D017610:Calcium Compounds; D004202:Disinfectants / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D010080:Oxazoles / Q000494:pharmacology*; D023303:Oxazolidinones; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012761:Shigella boydii / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship
D017610:Calcium Compounds; D004202:Disinfectants; D010080:Oxazoles; D023303:Oxazolidinones; C004488:calcium hypochlorite; C036350:3-chloro-4,4-dimethyl-2-oxazolidinone; D002118:Calcium