Antibiotic irrigations. A plea for controlled clinical trials.
Although the medical literature describes the perioperative use of antibiotic irrigations in abdominal, pelvic, orthopedic and vascular surgery, the lack of well-designed and executed, controlled clinical studies often precludes a definitive assessment of the value of this technique. Future randomized, double-blind, controlled clinical trials are required to establish its merit. In this age of cost consciousness, lavages with antibiotic solutions cannot at present be regarded as conventional medical therapy.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002585:Cesarean Section; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009985:Orthopedics; D010538:Peritonitis / Q000188:drug therapy; D011247:Pregnancy; D011292:Premedication; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000517:prevention & control; D007507:Therapeutic Irrigation; D014656:Vascular Surgical Procedures
D000900:Anti-Bacterial Agents