Etretinate therapy in generalized pustular psoriasis (Zumbusch type). Immediate and long-term results.
Etretinate therapy in 18 cases of generalized pustular psoriasis of the Zumbusch type proved to be effective and the therapy of choice. Only in 4 patients was maintenance therapy needed; in most cases relapses occurred after various intervals and patients responded invariably to reintroduction of the drug. Side-effects were slight. In 3 patients triglyceride levels became elevated, but only in 1 case the drug had to be withdrawn. In most of the patients generalized pustular eruption was accompanied, in some relapses or in some areas, by plaques of common psoriasis.
D000328:Adult; D000368:Aged; D002613:Cheilitis / Q000139:chemically induced; D005050:Etretinate / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008047:Lip Diseases / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy*; D012008:Recurrence; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides; D005050:Etretinate