Current trends in the research on antiinflammatory agents.
Current trends of pharmacological research on inflammation are outlined, with particular reference to some agents differing from the aspirin-like and the corticosteroids in their mode and mechanism of action. As an example, animal models used for the study of benzydamine, and its predominant features, are illustrated. A discussion is also made on the role of protein denaturation in inflammatory conditions where cell degeneration prevails over the active response, and the rationale used for developing bendazac is presented.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy / Q000209:etiology; D001241:Aspirin / Q000627:therapeutic use; D001591:Benzydamine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000209:etiology; D007565:Jaundice / Q000150:complications; D011247:Pregnancy; D011248:Pregnancy Complications; D011489:Protein Denaturation; D012106:Research
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D001591:Benzydamine; D001241:Aspirin