[Value of the assay of urinary neopterin in multiple myeloma. Preliminary study].
Urinary neopterin was assayed by HPLC (high performance liquid chromatography). 75 assays were performed in a population of 21 patients with multiple myeloma. There was a significant correlation between the urinary neopterin level and the electrophoretic peak, the R beta-2 microglobulinaemia ratio and the calculated tumour mass (Tbmc). This study demonstrates the value of this assay in the monitoring of patients with multiple myeloma.
D000368:Aged; D001708:Biopterins / Q000031:analogs & derivatives / Q000652:urine*; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000473:pathology / Q000652:urine*; D019798:Neopterin; D011621:Pteridines / Q000652:urine*; D001613:beta 2-Microglobulin / Q000032:analysis
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D011621:Pteridines; D001613:beta 2-Microglobulin; D001708:Biopterins; D019798:Neopterin
Intérêt du dosage de la néoptérine urinaire dans le myélome multiple. Etude préliminaire.