[The hematopoietic system in laboratory animals exposed to benzene].
The authors analysed, basing on literature, the mechanism of multitoxic effects of benzene and lesions in the peripheral blood of affected animals. The effects of chronic benzene poisoning upon erythrocytes and erythropoiesis, granulocytes and granulopoiesis, lymphocytes and lymphopoiesis, thrombocytes and thrombopoiesis were presented. Differences were pointed out in toxic effects of benzene varying with the kind, concentration and administration route of benzene and quantitative and qualitative differences in the fodder given to animals during the experiment.
D000818:Animals; D001554:Benzene / Q000506:poisoning*; D001853:Bone Marrow / Q000187:drug effects*; D004285:Dogs; D004912:Erythrocytes / Q000187:drug effects; D006400:Hematocrit; D006410:Hematopoiesis / Q000187:drug effects*; D007970:Leukopenia / Q000139:chemically induced; D051379:Mice; D008806:Mice, Inbred AKR; D008810:Mice, Inbred C57BL; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D013921:Thrombocytopenia / Q000139:chemically induced
D001554:Benzene
Narzad krwiotwórczy zwierzat laboratoryjnych eksponowanych na benzen.