[Dihydrocyclosporin D--a new immunosuppressive?].
The first preliminary clinical results with a new Cyclosporin derivative (Dihydrocyclosporin-D) are reported. The compound has no obvious nephrotoxic effect; but it exhibits a hepatotoxic effect, and frequently leads to hypertension. The clinical efficiency cannot yet be judged with certainty.
D001794:Blood Pressure / Q000187:drug effects; D002986:Clinical Trials as Topic; D003524:Cyclosporins / Q000627:therapeutic use* / Q000633:toxicity; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D007166:Immunosuppressive Agents; D008099:Liver / Q000187:drug effects / Q000473:pathology; D012216:Rheumatic Diseases / Q000188:drug therapy*
D003524:Cyclosporins; D007166:Immunosuppressive Agents; C041326:dihydrocyclosporin D
Dihydrocyclosporin-D--ein neues Immunsuppressivum?