Aluminum in the dialysis fluid.
The major source of aluminum in patients with chronic renal failure treated by hemodialysis is the hemodialysis fluid. The aluminum is derived from both the water and the chemical concentrate used in the preparation of the hemodialysis fluid. Due to the complex physico-chemistry of aluminum in water and dialysis fluid, both the total aluminum concentration and the proportion of aluminum species able to cross the hemodialysis membrane may vary from water supply to water supply and from day to day within a supply. A "safe" level of aluminum in dialysis fluid, which will prevent aluminum transfer from dialysis fluid to blood, and promotes aluminum removal from blood, has yet to be determined.
D000535:Aluminum / Q000032:analysis* / Q000302:isolation & purification; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006435:Renal Dialysis; D014462:Ultrafiltration; D006113:United Kingdom; D014511:Uremia / Q000097:blood; D014881:Water Supply / Q000032:analysis
D000535:Aluminum