[Vitamin A and vitamin E in dermatology].
Vitamin A is necessary to maintain the integrity and the differentiation of epithelia of the skin and adnexa. Evident deficiency of vitamin A in chronic diseases, malabsorption and liver affections may result in skin xerosis, follicular keratosis, and metaplasia of mucous membranes. The remarkable toxicity of vitamin A in high doses does not recommend its usage in dermatology. On the contrary the employ of retinoids, synthetic derivatives of vitamin A, brings to excellent results. These vitamin A compounds are much more effective, even if they show important side-effects. Etretinate and isotretinoin are widely used in psoriasis, keratinization disorders, and severe acne. Vitamin E functions in skin biology are not totally known. Vitamin E is used in the treatment of dermolytic recessive epidermolysis bullosa, with controversial results.
D003880:Dermatology; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology; D006801:Humans; D012176:Retinoids / Q000627:therapeutic use; D012867:Skin / Q000166:cytology; D012871:Skin Diseases / Q000188:drug therapy; D014801:Vitamin A / Q000502:physiology* / Q000627:therapeutic use; D014810:Vitamin E / Q000502:physiology* / Q000627:therapeutic use
D012176:Retinoids; D014801:Vitamin A; D014810:Vitamin E
La vitamina A e la vitamina E in dermatologia.