Effect of aspirin on nasal resistance to airflow.
The effect of aspirin on nasal resistance to airflow was investigated by rhinomanometry in 25 healthy subjects before and after ingestion of aspirin or vitamin C in a double blind crossover trial. Aspirin caused a significant increase in nasal resistance compared with vitamin C. The effect of aspirin may be due to its inhibition of the synthesis of prostaglandins.
D000328:Adult; D000403:Airway Resistance / Q000187:drug effects*; D001241:Aspirin / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009296:Nasal Cavity / Q000187:drug effects*
D001241:Aspirin