[Action of tomicide on bacterial cells. The bacteriostatic, bactericidal and bacteriolytic properties of tomicide].
The effect of the minimum bacteriostatic and bactericidal concentrations of native and concentrated tomicid on Staphylococcus aureus, Streptococcus hemolyticus and Micrococcus was studied. It was shown that the bactericidal effect of tomicid was attained with the use of the doses 2-10 times higher than those required for the bacteriostatic effect. The minimum concentrations of tomicid effective against gram-positive cocci varied within the ranges described for the other biologically active substances of bacterial origin. The dose-dependent lytic effect of tomicid was studied. It was found that for lysis of the cells it was necessary to doses significantly exceeding the bactericidal ones.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001430:Bacteriocins; D001433:Bacteriolysis / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008837:Micrococcus / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects; D013997:Time Factors
D000900:Anti-Bacterial Agents; D001430:Bacteriocins; C026129:tomicide
Izuchenie deĭstviia tomitsida na bakterial'nye kletki. Bakteriostaticheskie, bakteritsidnye i bakterioliticheskie svoĭstva tomitsida.