Production of monoclonal antibodies against Mycobacterium leprae and armadillo-derived mycobacteria.
Six monoclonal antibodies to Mycobacterium leprae and armadillo-derived mycobacteria were produced. The monoclonal antibodies were characterized by an immunofluorescence assay using 22 mycobacterial strains. One monoclonal antibody, F47-21-3, reacted only with M. leprae; two, F45-9 and F45-15, reacted only with two armadillo-derived mycobacterial strains. These six monoclonal antibodies can be used for the identification of M. leprae and armadillo-derived mycobacteria.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D001135:Armadillos / Q000382:microbiology*; D005455:Fluorescent Antibody Technique; D009161:Mycobacterium / Q000276:immunology*; D009166:Mycobacterium leprae / Q000276:immunology*; D004490:Xenarthra / Q000382:microbiology*
D000911:Antibodies, Monoclonal