Failure of the colloid oncotic-pulmonary artery wedge pressure gradient to predict changes in extravascular lung water.
Colloid oncotic pressure (COP), pulmonary artery wedge pressure (WP), and the COP-WP gradient were measured in seven critically ill adult patients and compared with extravascular lung water determined using the thermal-dye double-indicator dilution technique and a bedside lung water computer. Correlation coefficients for changes in extravascular lung water vs. COP, WP, and COP-WP were not significant, and in this patient population the COP-WP gradient did not predict changes in extravascular lung water.
D000328:Adult; D000368:Aged; D002199:Capillary Permeability; D003102:Colloids / Q000502:physiology*; D004395:Dye Dilution Technique; D005110:Extracellular Space / Q000502:physiology*; D005260:Female; D006801:Humans; D006874:Hydrostatic Pressure; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D009997:Osmotic Pressure; D011654:Pulmonary Edema / Q000503:physiopathology; D011669:Pulmonary Wedge Pressure; D012131:Respiratory Insufficiency / Q000503:physiopathology*; D013815:Thermodilution
D003102:Colloids