[Single-dose treatment of acute cystitis with norfloxacin. 1st report].
25 women with acute uncomplicated cystitis were treated with a single dose of 800 mg norfloxacin orally. Urinary checkups were performed 3 and 8 days after therapy and 4 and 8 weeks later. Urinary cultures, bacterial identification and antibiotic testing were performed. Success rate as based on the bacterial results was 96%. Reinfection occurred in one case only over the follow-up period of 8 weeks. This high success rate is due to strict selection of patients with truly uncomplicated cystitis and the beneficial chemotherapeutic effect of norfloxacin.
D000328:Adult; D003556:Cystitis / Q000188:drug therapy* / Q000382:microbiology; D004334:Drug Administration Schedule; D004926:Escherichia coli / Q000302:isolation & purification; D005260:Female; D006801:Humans; D009643:Norfloxacin / Q000008:administration & dosage*; D011549:Pseudomonas / Q000302:isolation & purification; D013210:Staphylococcus / Q000302:isolation & purification; D013291:Streptococcus / Q000302:isolation & purification
D009643:Norfloxacin
Einzeldosisbehandlung der akuten Zystitis mit Norfloxazin. Erste Ergebnisse.