Development of ovarian carcinoma in a cyclosporin A immunosuppressed patient.
This is the first report of an ovarian carcinoma developing in a patient immunosuppressed by Cyclosporin A. Thirteen months before the diagnosis of malignancy, the patient received a living related donor kidney transplant whose rejection was controlled by Cyclosporin A and prednisone. The tumor was rapidly fatal five weeks from diagnosis. The literature on malignant transformation in the immunosuppressed patient is reviewed with emphasis on a gynecologic perspective.
D000328:Adult; D003524:Cyclosporins / Q000009:adverse effects*; D005260:Female; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D016030:Kidney Transplantation; D010051:Ovarian Neoplasms / Q000209:etiology* / Q000648:ultrastructure; D011379:Prognosis; D012306:Risk
D003524:Cyclosporins