Aging immunocytes and immunity. Characteristics and significance.
With aging, many aspects of immune function change. Despite the greater complexity of problems and increased numbers of variables that attend research involving aged individuals, certain fundamental alterations in immune reactivity appear associated with aging. These alterations have important biologic implications. The immune changes in "healthy" octogenarians can have significant clinical effects when these individuals suffer stress or disease.
D000328:Adult; D000367:Age Factors; D000368:Aged; D000917:Antibody Formation; D003141:Communicable Diseases / Q000276:immunology; D006801:Humans; D007154:Immune System Diseases / Q000453:epidemiology; D007109:Immunity; D007111:Immunity, Cellular; D008214:Lymphocytes / Q000276:immunology*; D008875:Middle Aged; D008954:Models, Biological