Is there a limit on in situ, genomic replication in Drosophila?
The number of genomic replications of four separate tissues was determined in Drosophila melanogaster by summing the total number of nuclei and the maximum amount of DNA per nucleus in each tissue. It was found that for a given tissue the total number of nuclei was generally inversely proportional to the maximum amount of DNA per nucleus. In addition the sum of the number of divisions giving rise to the nuclei and the number of DNA replications occurring in the nucleus in each tissue never exceeded 20.
D000375:Aging; D000818:Animals; D002453:Cell Cycle; D004261:DNA Replication; D004331:Drosophila melanogaster / Q000166:cytology*; D014018:Tissue Distribution