[Biosynthesis of lytic enzymes in a mixed culture of actinomycetes and yeasts].
It was shown that S. levoris, an organism producing levorin, formed lytic enzymes in monocultures and in mixed cultures with C. tropicalis. Stimulation of the antibiotic production in the mixed cultures depended on the activity of lysoenzymes. When their activity was lowered by addition of cobalt salts to the medium the stimulating effect on the antibiotic synthesis was not observed. In cultivation of S. levoris and C. tropicalis it is necessary to provide optimal conditions for the growth of the yeasts and synthesis of the biostimulator by them and also for the simultaneous growth of the actinomycete and production of the antibiotic and lytic enzymes by it.
D000332:Aerobiosis; D002174:Candicidin / Q000096:biosynthesis; D003470:Culture Media / Q000378:metabolism; D005285:Fermentation; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D013302:Streptomyces / Q000201:enzymology*; D013997:Time Factors; D015003:Yeasts / Q000201:enzymology*
D003470:Culture Media; D002174:Candicidin; D010447:Peptide Hydrolases
Biosintez liticheskikh fermentov pri sovmestnom kul'tivirovanii aktinomitseta i drozhzheĭ.