[Aspiration of chorionic tissue: diagnostic potential in prenatal (fetal) diagnosis].
The authors have investigated the possibilities of obtaining chorionic villi from legal pregnancy termination patients between the 7th and 11th week and the method of direct chromosome preparation from the villi as well. According to their investigations under continuous "real time" ultrasound guidance and with the immediate microscopic checking of the obtained material it is possible to receive chorionic villi of necessary quantity in nearly 100% of the cases, and after 2 or 3 hours the evaluation in a great deal of mitosis of good quality can be carried out. The method may revolutionize the prenatal (fetal) diagnosis, but its routine application may not be proposed until the rate of fetal risk is exactly known.
D001707:Biopsy, Needle / Q000379:methods*; D002823:Chorion / Q000473:pathology* / Q000648:ultrastructure; D002877:Chromosomes, Human / Q000648:ultrastructure; D004247:DNA / Q000032:analysis; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006453:Hemoglobinopathies / Q000175:diagnosis; D006801:Humans; D007621:Karyotyping; D008297:Male; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis / Q000379:methods*; D012732:Sex Determination Analysis; D014463:Ultrasonography
D004247:DNA
Aspiration des Choriongewebes: Eine neue Möglichkeit in der pränatalen (fetalen) Diagnostik.