Serum beta 2-microglobulin in systemic sclerosis.
The role of beta 2 microglobulin (beta 2-m) in Systemic Sclerosis (SS) has been evaluated. Twenty-four female patients have been examined: 15 of them were affected by acrosclerosis (Group 1) and 9 of them by diffuse sclerosis (Group 2). 46.6% of Group 1 and 44.4% of Group 2 had values significantly higher than normal controls. (P less than 0.01 and P less than 0.005 respectively). The authors deal with the validity of the use of B2-m as index of inflammatory activity of the disease.
D000328:Adult; D000368:Aged; D001799:Blood Sedimentation; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000276:immunology*; D000515:alpha 1-Antitrypsin / Q000032:analysis; D001613:beta 2-Microglobulin / Q000032:analysis*
D003176:Complement C3; D003181:Complement C4; D000515:alpha 1-Antitrypsin; D001613:beta 2-Microglobulin