Multiple myeloma with initial presentation in the jaw: a clinical-pathologic discussion.
A 39-year-old white female presented with jaw pain initially interpreted as a manifestation of an odontogenic infection. Mandibular radiographs revealed lytic lesions suggesting a diagnosis of myeloma, which was subsequently confirmed by abnormalities in serum and urinary proteins and in bone marrow. Chemotherapy produced a transient response, but eventual relapse with extramedullary plasmacytomas and plasma cell leukemia led to death. The clinicopathologic implications of this case are presented and discussed.
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007573:Jaw Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D009101:Multiple Myeloma / Q000000981:diagnostic imaging / Q000473:pathology*; D009361:Neoplasm Invasiveness; D014057:Tomography, X-Ray Computed