Primary amyloidosis with increased plasma carcinoembryonic antigen concentration. A case report.
A patient with suspected malignant disease had increased concentration of plasma carcinoembryonic antigen (CEA). Amyloidosis was demonstrated at autopsy. The amyloid fibril composition was characterized by immunohistochemical and immunochemical techniques and proved to be of the lambda light chain (AL) type. CEA was demonstrated in the liver parenchyma by using antihuman CEA antiserum. Increased plasma CEA concentration in a patient with primary amyloidosis has, to our knowledge, not been reported before.
D000368:Aged; D000686:Amyloidosis / Q000276:immunology* / Q000473:pathology; D001344:Autopsy; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D008099:Liver / Q000276:immunology / Q000473:pathology
D002272:Carcinoembryonic Antigen; D007146:Immunoglobulin lambda-Chains