Reliability of single kidney glomerular filtration rate measured by a 99mTc-DTPA gamma camera technique.
The reliability of a previously published method for determination of single kidney glomerular filtration rate (SKGFR) by means of technetium-99m-diethylenetriaminepenta-acetate (99mTc-DTPA) gamma camera renography was evaluated. The day-to-day variation in the calculated SKGFR values was earlier found to be 8.8%. The technique was compared to the simultaneously measured renal clearance of inulin in 19 unilaterally nephrectomized patients with GFR varying from 11 to 76 ml/min. The regression line (y = 1.04 X -2.5) did not differ significantly from the line of identity. The standard error of estimate was 4.3 ml/min. In 17 patients the inter- and intraobserver variation of the calculated SKGFR values was 1.2 ml/min and 1.3 ml/min, respectively. In 21 of 25 healthy subjects studied (age range 27-29 years), total GFR calculated from the renograms was within an established age-dependent normal range of GFR.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005919:Glomerular Filtration Rate; D006801:Humans; D007444:Inulin; D007674:Kidney Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007678:Kidney Glomerulus / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008875:Middle Aged; D004369:Pentetic Acid; D011866:Radioisotope Renography; D013667:Technetium; D016284:Technetium Tc 99m Pentetate
D013667:Technetium; D004369:Pentetic Acid; D007444:Inulin; D016284:Technetium Tc 99m Pentetate