Characteristics of a feline mammary carcinoma cell line.
The establishment of an epithelial cell line, JM, from a feline mammary adenocarcinoma is described. In vitro, the morphological and cultural properties of these cells, their surface features such as lectin binding and their response to hormones were ascertained. In vivo, they are tumorigenic in athymic nude mice inducing tumour nodules composed of epithelia-like cells.
D000230:Adenocarcinoma / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D002460:Cell Line; D005260:Female; D005353:Fibronectins / Q000032:analysis; D005455:Fluorescent Antibody Technique; D008321:Mammary Glands, Animal; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000473:pathology / Q000662:veterinary*; D012190:Retroviridae / Q000302:isolation & purification
D005353:Fibronectins