C-reactive protein binds leishmanial excreted factors.
Excreted factors from Leishmania tropica and Leishmania donovani are precipitated by human and rabbit C-reactive protein. The reaction is calcium dependent and appears to be similar to that reported to occur between C-reactive protein and various galactans. The absence of phosphate and N-acetyl galactosamine suggests that the reaction is not the result of any similarity of the excreted factors to pneumococcal C-polysaccharide.
D000953:Antigens, Protozoan / Q000378:metabolism / Q000652:urine*; D000954:Antigens, Surface / Q000276:immunology*; D002097:C-Reactive Protein / Q000378:metabolism*; D006801:Humans; D005779:Immunodiffusion; D007891:Leishmania / Q000276:immunology*; D010587:Phagocytosis
D000953:Antigens, Protozoan; D000954:Antigens, Surface; D002097:C-Reactive Protein