Multiple organ procurement from one donor.
To maximize organ utilization, we assessed the feasibility of retrieving the heart and two single lungs or the heart and a separate bilateral lung block for transplantation into multiple recipients. In eight dogs the excision of the heart-lung block or of the left lung was followed by six hours of lung preservation. Four of these lungs and all eight hearts were transplanted successfully. In addition, satisfactory retrieval of the three separate organs or of the heart and a separate bilateral lung block was done in six human cadavers. An appropriate division of the left atrial wall provided suitable cuffs for individual transplantation of the three organs or for the heart and bilateral lung block. This study demonstrates the feasibility of multiple organ donation from a single donor followed by separate organ transplantation.
D000818:Animals; D004285:Dogs; D006085:Graft Survival; D016027:Heart Transplantation; D006801:Humans; D016040:Lung Transplantation; D014019:Tissue Donors; D009927:Tissue and Organ Procurement; D014184:Transplantation, Homologous / Q000379:methods