Inhibition of Candida albicans by methanethiol produced by Brevibacterium linens.
Brevibacterium linens was screened for antifungal activity against Candida albicans using several antibiotic assay methods. The growth of C. albicans was inhibited only when the dual culture assay method was employed and using methionine-supplemented media. Results suggest that methanethiol which is produced by B. linens' utilization of methionine is the agent inhibitory to C. albicans' growth.
D001951:Brevibacterium / Q000254:growth & development*; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development; D003470:Culture Media; D008826:Microbial Sensitivity Tests; D013438:Sulfhydryl Compounds / Q000096:biosynthesis / Q000494:pharmacology*
D003470:Culture Media; D013438:Sulfhydryl Compounds; C005231:methylmercaptan