A prognostic inflammatory and nutritional index scoring critically ill patients.
A new prognostic inflammatory and nutritional index is described allowing the correct follow-up of most pathological conditions. Discriminant analysis of eleven currently utilized blood markers of the phlogistic reaction and of the nutritional status has afforded the selection of the two most reliable acute-phase reactants (orosomucoid and C-reactive protein) and visceral proteins (albumin and prealbumin). These parameters are combined in a simple formula which consistently and accurately stratifies critically ill patients by risk of complications or death. The grading system is determined by a rapid and inexpensive micromethod encompassing both infectious and nutritional poles of the disease spectrum within a self-explanatory scale. The scoring system provides a more sensitive tool for the diagnosis and prognosis of stressed patients than any other method available to date.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D005260:Female; D006801:Humans; D007239:Infections / Q000175:diagnosis*; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D009961:Orosomucoid / Q000378:metabolism; D011228:Prealbumin / Q000378:metabolism; D011379:Prognosis; D011502:Protein-Energy Malnutrition / Q000175:diagnosis*; D012306:Risk; D012709:Serum Albumin / Q000378:metabolism; D013975:Thyroxine-Binding Proteins / Q000378:metabolism
D009961:Orosomucoid; D011228:Prealbumin; D012709:Serum Albumin; D013975:Thyroxine-Binding Proteins; D002097:C-Reactive Protein