Cromolyn sodium.
Cromolyn sodium is a valuable agent in the pharmacologic management of asthma. In addition to its established effects of inhibiting mediator release, it now appears that it is a useful drug for diminishing the effects of reflex-mediated asthma, nonspecific bronchial hyperreactivity, and diurnal swings of bronchial lability. Because of these unique prophylactic properties, the availability of a nebulized aqueous solution delivery system and recent clinical reports showing that its efficacy is comparable to theophylline, cromolyn sodium should be reconsidered as a first-line antiasthmatic drug in the United States.
D000281:Administration, Intranasal; D000336:Aerosols; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D004205:Cromolyn Sodium / Q000266:history / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D004311:Double-Blind Method; D049673:History, 20th Century; D006801:Humans; D007700:Kinetics; D008407:Mast Cells / Q000187:drug effects; D010349:Patient Compliance
D000336:Aerosols; D004205:Cromolyn Sodium