[Nature of the change in cytostatic and cytotoxic splenocyte functions in mice after immobilization stress].
It has been shown that at late periods after immobilization stress there is an essential reduction in the cytostatic activity of CBA mice splenocytes detected by inhibition of mastocytoma P 815 cell proliferation in the test with 3H-uridine incorporation. The cytostatic activity returns to normal 5 to 14 days after stress. The changes in the cytolytic and cytostatic activity of mouse splenocytes following stress are correlated and a possible biological value of changes in the immunoassays for the host are discussed.
D000818:Animals; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology; D008297:Male; D012515:Mast-Cell Sarcoma / Q000276:immunology; D051379:Mice; D008808:Mice, Inbred CBA; D012149:Restraint, Physical; D013154:Spleen / Q000276:immunology*; D013315:Stress, Psychological / Q000276:immunology*; D013997:Time Factors
Kharakter izmeneniia tsitostaticheskoĭ i tsitotoksicheskoĭ funktsiĭ splenotsitov mysheĭ posle immobilizatsionnogo stressa.