Neonatal sepsis.
Neonates are susceptible to infection since several elements of the immune system are deficient. At present, the most common pathogens are Group B streptococci and Escherichia coli. Prolonged rupture of membranes with amnionitis is a high-risk setting. Clinical signs suggesting neonatal sepsis include respiratory distress, poor feeding, hypothermia, seizures and hypotonia. After the sepsis work-up is completed, the initial choice of antibiotics is based on the prevailing organisms and antibiotic sensitivities within the community.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000175:diagnosis / Q000209:etiology / Q000276:immunology / Q000628:therapy; D004927:Escherichia coli Infections; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D006801:Humans; D007109:Immunity; D007231:Infant, Newborn; D011247:Pregnancy; D012306:Risk; D013129:Spinal Puncture; D013290:Streptococcal Infections; D013292:Streptococcus agalactiae
D000900:Anti-Bacterial Agents