[Effect of the consumption of krill protein isolates on lysosomal proteinase activity in rats].
A study was made of the total and nonsedimented activity of 4 lysosomal proteinases in the liver, kidneys and blood serum of rats fed for 4 months krill protein isolate (AtlantNIRO) as the only source of protein or that replaced by 50% with a control protein (casein) contained by the 18% protein (in terms of caloricity) diet. The use of the krill isolate as the only source of protein brought about a significant increase in the total activity of cathepsin A and cathepsin D and in nonsedimented activity of cathepsins A, D, B and C in rat liver (by 95, 23, 32 and 50%, respectively). Meanwhile in the kidneys, there was an increase in the total activity of cathepsins A and D. Proteinases A, D, B and C were activated in the blood serum. The 50% replacement of the krill isolate by casein elicited a substantial decrease in the adverse effect of the krill protein isolate on metabolic processes in rats.
D000818:Animals; D002364:Caseins / Q000008:administration & dosage; D002403:Cathepsins / Q000378:metabolism; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D010450:Endopeptidases / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D010933:Plankton; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D015048:Zooplankton
D002364:Caseins; D004044:Dietary Proteins; D002403:Cathepsins; D010450:Endopeptidases
Vliianie potrebleniia izoliata krilevogo belka na aktivnost' proteinaz lizosom u krys.