The anti-allergic effects of FPL 52694.
The substituted chromone carboxylic acid FPL 52694 inhibited models of IgE-mediated immediate hypersensitivity reactions in the rat by a mechanism similar to that of sodium cromoglycate. The compound was more potent than sodium cromoglycate but unlike cromoglycate was active following oral administration.
D000284:Administration, Oral; D000818:Animals; D002867:Chromones / Q000008:administration & dosage / Q000276:immunology*; D004205:Cromolyn Sodium / Q000276:immunology; D006969:Hypersensitivity, Immediate / Q000517:prevention & control*; D007073:Immunoglobulin E / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D051381:Rats
D002867:Chromones; D007073:Immunoglobulin E; C029061:FPL-52694; D004205:Cromolyn Sodium