[Bornaprine in the treatment of parkinsonian tremor].
We report the results of a double-blind placebo controlled study of bornaprine, an anticholinergic drug, in the treatment of Parkinson's disease. We studied 17 patients presenting persistent tremor in spite of a stable long-term L-Dopa therapy. The bornaprine, in doses of 8 mg/die, compared with placebo significantly improves tremor. Only mild side effects occurred. We think the bornaprine may be of value in the treatment of parkinsonian tremor.
D000978:Antiparkinson Agents / Q000627:therapeutic use*; D001952:Bridged-Ring Compounds / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy*; D014786:Vision Disorders / Q000139:chemically induced
D000978:Antiparkinson Agents; D001952:Bridged-Ring Compounds; C006088:bornaprine
Il bornaprine nel trattamento del tremore parkinsoniano.