Sources and fate of polychlorinated dibenzodioxins, dibenzofurans and related compounds in human environments.
Several of the major incidents resulting in potential human exposures to polychlorinated dibenzodioxins (PCDDs) and/or polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs) and related compounds which have occurred in the U.S. in recent periods have resulted from improper disposal of hazardous chemical wastes. Prominent examples of such environmental contamination episodes are the Love Canal, into which ton quantities of chlorinated organic compounds containing substantial concentrations of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were deposited; numerous sites in the State of Missouri which were contaminated by the dumping of chlorinated organic wastes containing various PCDDs and possibly PCDFs, and PCBs; and the environs of a 2,4-D/2,4,5-T manufacturing plant site in Arkansas, which were contaminated with PCDDs. Environmental assessments of such sites have revealed extensive contamination of soils, waterways, fish and other biological species with these toxic compounds, which in turn could lead to human exposures. Other recently identified sources of PCDDs, PCDFs and related compounds in human environments include stack effluents from municipal refuse incineration, and fires and explosions involving electrical devices containing PCBs and polychlorinated benzenes. Data obtained in assessments of such incidents are presented, and the implications of these findings with respect to the distribution and persistence of PCDDs, PCDFs and related chemicals in the environment and possible effects on humans are discussed.
D000059:Accidents; D001572:Benzofurans / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D002733:Chlorophenols; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins / Q000032:analysis; D004785:Environmental Pollutants; D006358:Hot Temperature; D006843:Hydrocarbons, Chlorinated; D008923:Missouri; D009518:New York; D011078:Polychlorinated Biphenyls / Q000032:analysis; D012037:Refuse Disposal / Q000379:methods
D001572:Benzofurans; D002733:Chlorophenols; D000072338:Dibenzofurans, Polychlorinated; D004147:Dioxins; D004785:Environmental Pollutants; D006843:Hydrocarbons, Chlorinated; D011078:Polychlorinated Biphenyls