[Keratomalacia perforans, clinical and pathohistologic findings].
This report deals on the course of disease in an 82-year-old patient with keratomalacia perforans with seropositive chronic polyarthritis. In the more severely affected eye there was a marginal corneal ulcer extending over two quadrants and close to perforation. Six months after total keratoplasty, in which the corneal transplant including marginal scleral tissue was resected and transplanted, a recurrent ulcer was observed at the same location. It proved impossible to prevent rejection of the transplanted tissue despite therapy with antiphlogistic and immunsuppressive drugs. The ulcer subsequently perforated. Histologically a plasmacellular infiltration was observed which was more severe in the areas close to the perforation.
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000473:pathology*; D003315:Cornea / Q000473:pathology; D016039:Corneal Transplantation; D003320:Corneal Ulcer / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000473:pathology; D012008:Recurrence
Keratomalacia perforans, klinische und pathohistologische Befunde.