Idiopathic myelofibrosis complicated by lymphoma. Report of two cases.
2 cases of diffuse large-cell non-Hodgkin's lymphoma developing in conjunction with idiopathic myelofibrosis are described. In neither case could any predisposition to neoplastic transformation be discerned. The possible pathogenetic implications of this association are discussed, and a brief literature review of the relationship between myeloproliferative and lymphoproliferative disease is presented.
D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D006801:Humans; D008223:Lymphoma / Q000150:complications* / Q000473:pathology; D008297:Male; D055728:Primary Myelofibrosis / Q000150:complications* / Q000473:pathology