Application of microvascular free osteocutaneous flaps in the management of post-radiation recurrent oral cancer.
Fifty-nine patients underwent free flap osteocutaneous reconstruction that consisted of flaps of the dorsum of the foot in 26 patients and iliac crest flaps in 33 with a success rate of 92 percent and a mortality rate of 1.6 percent. These flaps, which require the expertise of microvascular surgeons, are time-consuming and complicate operating room and time management, but they represent a remarkable advance in reconstruction that can facilitate cosmetic and functional recovery of the patient. In particular, they promote healing in radiation-recurrent oral cancer and represent a definitive form of management for established radionecrosis of the mandible. The large volume of tissue available with iliac crest osteocutaneous grafts permits the management of patients with extensive cancer involving the skin, mucosa, and bone, but cancer control may still be disappointing and there is a need for improved adjuvant chemotherapy protocols. This technique appears to be a dependable, repeatable, and significant advance in management of the patient with head and neck cancer.
D000328:Adult; D000368:Aged; D016025:Bone Transplantation; D001842:Bone and Bones / Q000098:blood supply; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery*; D008336:Mandibular Diseases / Q000209:etiology / Q000601:surgery; D008833:Microcirculation; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000209:etiology / Q000532:radiotherapy / Q000601:surgery*; D009381:Neoplasms, Radiation-Induced / Q000601:surgery*; D010025:Osteoradionecrosis / Q000601:surgery; D013518:Surgery, Plastic / Q000379:methods*; D013524:Surgical Flaps