Peritonitis in the newborn--current concepts.
The author provides well-detailed discussion of peritonitis in the newborn and draws the following conclusions. Prognosis for neonates with gastrointestinal perforation has considerably improved and will continue to improve. Sepsis remains the primary cause of death, with necrotizing enterocolitis the most common cause of perforation. The characteristic gastrointestinal microflora and innate immunologic deficiency of this population, particularly in the critically ill preterm neonate, require further delineation.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D001769:Blood / Q000382:microbiology; D004064:Digestive System / Q000382:microbiology; D005260:Female; D006801:Humans; D007113:Immunity, Innate; D007231:Infant, Newborn; D007416:Intestinal Perforation / Q000209:etiology / Q000601:surgery; D008297:Male; D010537:Peritoneum / Q000382:microbiology; D010538:Peritonitis / Q000145:classification / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D007507:Therapeutic Irrigation
D000900:Anti-Bacterial Agents