Intensive care course after orthotopic liver transplantation in children.
Eight children 1 to 13 years old, were submitted to OLT. Six patients had normal liver function and complete rehabilitation 4 to 17 months after OLT. Two patients died during their ICU course respectively on day 15 and 34 after operation. The ICU management of the surviving patients is compared to the two fatal cases. At the time of admission in the ICU, there was no difference between the two groups, except for age. All patients were physiologically stable and needed essentially continuous monitoring and nursing care. All were rapidly weaned off artificial ventilation. During the first week after operation, surviving patients demonstrate improvement of liver function test, absence of infection, normal renal function and short ICU stay. They all suffered from systemic hypertension easily controlled by drugs. The two fatal cases were less than 15 months old and did not show improvement of their liver function. They suffered from severe infection, renal failure and protracted systemic hypertension and needed prolonged invasive monitoring and therapy.
D000293:Adolescent; D001652:Bile Ducts / Q000002:abnormalities*; D002648:Child; D002675:Child, Preschool; D003414:Crigler-Najjar Syndrome / Q000601:surgery; D003422:Critical Care; D006801:Humans; D007223:Infant; D016031:Liver Transplantation; D011182:Postoperative Care; D019896:alpha 1-Antitrypsin Deficiency