[Temperature-dependent effects of lidocaine-CO2 in peridural anesthesia].
Lidocaine CO2, used for anaesthesia in 26 gynaecological and urological patients, was injected into the epidural space at two temperatures -20 degrees C and 36 degrees C. We found that the higher temperature resulted in a faster onset of blockade, a longer duration of action, and a greater degree of motor blockade. We found, also, with the warmed solution a higher spread of analgesia, which could enable a reduction to be made in the volume necessary for satisfactory anaesthesia.
D000767:Anesthesia, Epidural; D002245:Carbon Dioxide; D006801:Humans; D008012:Lidocaine; D009469:Neuromuscular Junction / Q000187:drug effects; D013696:Temperature; D013997:Time Factors
D002245:Carbon Dioxide; D008012:Lidocaine
Temperaturabhängige Wirkungen von Lidocain-CO2 in der Periduralanaesthesie.