HNK-I antibody reacts with peripheral nerves and sweat glands in the skin.
The distribution of Leu-7 antigen was investigated using immunoperoxidase staining technique. It was found that HNK-I monoclonal antibody reacted with peripheral nerves and sweat glands (both apocrine and eccrine) of the skin. HNK-I antibody is a new marker for them, and may help to elucidate the nature of some skin tumours.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface / Q000032:analysis*; D001050:Apocrine Glands / Q000276:immunology; D004439:Eccrine Glands / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D007694:Killer Cells, Natural / Q000276:immunology*; D010525:Peripheral Nerves / Q000276:immunology*; D012867:Skin / Q000276:immunology / Q000294:innervation; D013545:Sweat Glands / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface