[A study on transference of cefminox into intrapelvic tissues].
Intravenous administrations of cefminox (CMNX, MT-141) 1 g as both single shot injection and drip infusion were absorbed rapidly. CMNX showed good transference into intrapelvic organs such as uterus, oviduct and ovary, with the tissue/serum ratios of 37.6% for myometrium, 35.1% for endometrium, 41.4% for cervix uteri, 49.5% for portio vaginalis, 54.3% for ovary and 59.7% for oviduct. From these results, usefulness of CMNX in the field of obstetrics and gynecology was confirmed.
D002513:Cephamycins / Q000097:blood / Q000378:metabolism*; D005187:Fallopian Tubes / Q000378:metabolism; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D007275:Injections, Intravenous; D007700:Kinetics; D010053:Ovary / Q000378:metabolism; D010388:Pelvis / Q000378:metabolism*; D014599:Uterus / Q000378:metabolism
D002513:Cephamycins; C046079:cefminox