Comparison of vitreous replacement with Healon and with HPMC in rabbits' eyes.
Ten rabbits underwent vitreous aspiration and replacement by either Healon or Hydroxy Propyl Methyl Cellulose 2%. Four weeks' observation did not reveal noticeable differences between Healon and HPMC with regard to anterior chamber reaction, intra-ocular pressure or cataract. The vitreous reaction in eyes with HPMC was much more severe than in Healon eyes, with typical white precipitates and vitreous bands. Post-mortem examination confirmed the clinical findings.
D000818:Animals; D000867:Anterior Chamber / Q000187:drug effects / Q000473:pathology; D004343:Drug Implants; D006820:Hyaluronic Acid / Q000008:administration & dosage* / Q000627:therapeutic use; D065347:Hypromellose Derivatives; D007429:Intraocular Pressure / Q000187:drug effects; D008747:Methylcellulose / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011180:Postmortem Changes; D011817:Rabbits; D014821:Vitrectomy / Q000379:methods; D014822:Vitreous Body / Q000187:drug effects / Q000473:pathology
D004343:Drug Implants; D065347:Hypromellose Derivatives; D006820:Hyaluronic Acid; D008747:Methylcellulose