title: New evidence for taurine biosynthesis in man obtained from 18O2 inhalation studies.
abstract: The ability of adult humans to synthesize taurine was assessed by measurement of the 18O content of urinary taurine in eight subjects following 60 minutes inhalation of 18O2 (97% 18O). All subjects had at least one 3-hour urine collection in which the mole ratio of 18O-taurine to taurine was at least three times greater than the standard deviation of the stable isotope measurement. The peak mole ratios of 18O-taurine/16O-taurine ranged from 0.0075 to 0.015. These data indicated that adult human subjects have a significant ability to synthesize taurine.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010103:Oxygen Isotopes; D013654:Taurine / Q000096:biosynthesis* / Q000652:urine
chemical_list: D010103:Oxygen Isotopes; D013654:Taurine