title: Amniotic tissue transplantation as a trial of treatment in some lysosomal storage diseases.
abstract: This communication reports the clinical and biochemical results in six patients: four with mucopolysaccharidosis, one with GM1 gangliosidosis (Morquio B) and one with I-cell disease, who were treated by amniotic tissue transplantation. The sole evident clinical result was the diminishing of corneal clouding in three cases. A slight increase of beta-galactosidase activity in one patient's plasma was observed. The time of improvement was about 2 months after the transplantation and was transitory.
mesh_terms: D000650:Amnion / Q000637:transplantation*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005677:G(M1) Ganglioside / Q000378:metabolism; D005733:Gangliosidoses / Q000628:therapy*; D006801:Humans; D008297:Male; D009081:Mucolipidoses / Q000628:therapy*; D009083:Mucopolysaccharidoses / Q000628:therapy*; D008059:Mucopolysaccharidosis I / Q000628:therapy; D009087:Mucopolysaccharidosis VI / Q000628:therapy
chemical_list: D005677:G(M1) Ganglioside