title: [Changes in the concentration of metalloproteins in the blood plasma in hypoxia and hyperbaric oxygenation].
abstract: Dynamics of hemoglobin, ceruloplasmin concentration, the changes of chemiluminescence in blood plasma and kinetics of rat erythrocyte heat denaturation during consequent exposition of high altitude hypoxia and hyperbaric oxygenation have been studied. Severe hypoxia causes the decrease of extraerythrocyte hemoglobin and oxidase activity of ceruloplasmin. Reoxygenation results in significant increase of blood plasma chemiluminescence with simultaneous increase of extraerythrocyte hemoglobin level and with modification of surface structure of the erythrocyte membranes. Possible pathways of activation of oxygen-dependent of free-radical processes during reoxygenation are discussed.
mesh_terms: D000818:Animals; D001273:Atmosphere Exposure Chambers; D002570:Ceruloplasmin / Q000032:analysis; D004910:Erythrocyte Membrane / Q000378:metabolism; D005609:Free Radicals; D006454:Hemoglobins / Q000032:analysis; D006358:Hot Temperature; D006931:Hyperbaric Oxygenation; D000860:Hypoxia / Q000097:blood*; D007700:Kinetics; D008163:Luminescent Measurements; D008297:Male; D008667:Metalloproteins / Q000097:blood*; D010544:Peroxidases / Q000097:blood; D011489:Protein Denaturation; D051381:Rats
chemical_list: D005609:Free Radicals; D006454:Hemoglobins; D008667:Metalloproteins; D010544:Peroxidases; D002570:Ceruloplasmin
vernacular_title: Izmenenie kontsentratsii metallosoderzhashchikh belkov v plazme krovi pri gipoksii i giperbaricheskoĭ oksigenatsii.