Diurnal administration of human growth hormone-releasing factor does not modify sleep and sleep-related growth hormone secretion in normal young men.
hGRF (iv 50 micrograms) was administered to 6 normal young adult males at 09.00 and 20.00 h on different days. Nocturnal GH secretion was monitored during polygraphic sleep recordings on both control nights and nights following hGRF administration. Sleep-related GH secretion and sleep parameters were not affected by diurnal hGRF administration.
D000328:Adult; D000367:Age Factors; D002940:Circadian Rhythm; D013006:Growth Hormone / Q000378:metabolism*; D013007:Growth Hormone-Releasing Hormone / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D012737:Sex Factors; D012890:Sleep; D012894:Sleep Stages
D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone