title: Distribution of cathepsin D immunoreactivity in the central nervous system of rat and selected brain regions of man.
abstract: The regional distribution and cellular localization of cathepsin D immunoreactivity was demonstrated at the light microscopic level in the CNS of rat and man by use of unlabelled immunoenzyme technique. A wide but uneven distribution was substantiated for the rat brain. Furthermore, we present evidence that antiserum produced against rat liver enzyme is capable of recognizing cathepsin D in human brain.
mesh_terms: D000818:Animals; D000937:Antigen-Antibody Reactions; D001921:Brain / Q000201:enzymology*; D002402:Cathepsin D / Q000032:analysis* / Q000276:immunology; D005260:Female; D006624:Hippocampus / Q000201:enzymology; D006801:Humans; D007031:Hypothalamus / Q000201:enzymology; D007124:Immunoenzyme Techniques; D008297:Male; D009474:Neurons / Q000032:analysis*; D051381:Rats; D013116:Spinal Cord / Q000201:enzymology*
chemical_list: D002402:Cathepsin D