Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody.
An mAb, NLDC-145, is described that specifically reacts with a group of nonlymphoid dendritic cells including Langerhans cells (LC), veiled cells (VC), and interdigitating cells (IDC). The antibody does not react with precursor cells in bone marrow and blood. Macrophages are not stained by the antibody, but a subpopulation of Ia+ peritoneal exudate cells is recognized. Possible relationships of the various nonlymphoid dendritic cell (NLDC) types are discussed.
D000818:Animals; D000911:Antibodies, Monoclonal; D001854:Bone Marrow Cells; D007801:Langerhans Cells / Q000276:immunology*; D008221:Lymphoid Tissue / Q000166:cytology*; D008264:Macrophages / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008970:Molecular Weight; D010529:Peritoneal Cavity / Q000166:cytology; D051381:Rats; D012867:Skin / Q000166:cytology
D000911:Antibodies, Monoclonal