Cutaneous malignant lymphomas. A clinicopathologic study of thirty-seven cases.
Clinical and histological findings in 37 cases of cutaneous lymphomas other than mycosis fungoides and Sezary syndrome were investigated; there were 31 in adults and 6 in children. Cutaneous lesions were the first manifestations of the diseases in all cases, and they appeared mostly as tumors or nodules. Cytomorphologically, about a half of the cases showed proliferations of large cleaved, non-cleaved cells or immunoblasts (Group I). Eight cases showed a polymorphous appearance containing convoluted cells of various size (Group II). Five cases in children demonstrated monomorphous proliferation of uniform-sized lymphoblasts (Group III). The cytologic findings in 6 cases did not fit into any lymphoid groups (Group IV). The clinical findings observed in each group were reviewed and compared. Follow-up study revealed that the prognosis of Group I was the poorest among the four groups.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000944:Antigens, Differentiation, B-Lymphocyte; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008222:Lymphokines / Q000032:analysis; D008223:Lymphoma / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000032:analysis; D011379:Prognosis; D011947:Receptors, Antigen, B-Cell / Q000032:analysis; D012397:Rosette Formation; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*
D000944:Antigens, Differentiation, B-Lymphocyte; D008222:Lymphokines; D011947:Receptors, Antigen, B-Cell; D009113:Muramidase