Sulfur and calcific keratopathy associated with retinal detachment surgery and vitrectomy.
We report an unusual case of extensive sulfur and calcium deposition in the cornea after retinal detachment surgery, vitrectomy, and use of topical sulfacetamide. There were no signs of anterior segment ischemia and intraocular silicone oil was not used. Light and electron microscopic examination and x-ray energy dispersive analysis are described. A possible mechanism for the pathogenesis of this condition is presented.
D000328:Adult; D002118:Calcium / Q000378:metabolism*; D003315:Cornea / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure; D003316:Corneal Diseases / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D004577:Electron Probe Microanalysis; D006801:Humans; D008297:Male; D011182:Postoperative Care; D011183:Postoperative Complications; D012163:Retinal Detachment / Q000601:surgery*; D013409:Sulfacetamide / Q000009:adverse effects / Q000627:therapeutic use; D013455:Sulfur / Q000378:metabolism*; D014821:Vitrectomy / Q000009:adverse effects*
D013409:Sulfacetamide; D013455:Sulfur; D002118:Calcium