[Physicochemical study of the state of protein and lipid phases in synaptosome membranes following irradiation with fast electrons].
No activation of lipid peroxidation and structural rearrangements were noted in the lipid phase of synaptosome membranes after exposure of animals to electrons of 300 Gy/min at doses inducing cerebral lesions. At the same time, in isolated synaptosome membranes, radiation induced defined changes manifested by a decrease in tryptophan fluorescence.
D000818:Animals; D002540:Cerebral Cortex / Q000166:cytology; D004583:Electrons; D005456:Fluorescent Dyes; D066298:In Vitro Techniques; D008054:Lipid Peroxides / Q000096:biosynthesis; D008297:Male; D008563:Membrane Lipids / Q000528:radiation effects*; D008565:Membrane Proteins / Q000528:radiation effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013574:Synaptosomes / Q000528:radiation effects*; D014364:Tryptophan
D005456:Fluorescent Dyes; D008054:Lipid Peroxides; D008563:Membrane Lipids; D008565:Membrane Proteins; D014364:Tryptophan
Fiziko-khimicheskoe issledovanie sostoianiia belkovoĭ i lipidnoĭ faz v membranakh sinaptosom posle oblucheniia bystrymi élektronami.