title: Epithelial cells of the normal human breast.
abstract: A comparison has been made of the effects of different fixation protocols upon the ultrastructure of normal human breast. Pale (B) and dark (A) epithelial cells as described by previous authors are present in tissue fixed with hyperosmotic Karnovsky-type fixatives, but not where the primary fixative is isosmotic glutaraldehyde. The observed subpopulations of pale and dark epithelial cells have been directly compared with sub-groups of epithelial cells recognized by the monoclonal antibody LICR-LON-M8. The pale and dark cells bear no relation to the subpopulations of epithelial cells depicted by LICR-LON-M8.
mesh_terms: D000911:Antibodies, Monoclonal; D001940:Breast / Q000276:immunology / Q000648:ultrastructure*; D004848:Epithelium / Q000276:immunology / Q000648:ultrastructure; D005260:Female; D005404:Fixatives; D005976:Glutaral; D006652:Histological Techniques; D006801:Humans; D008854:Microscopy, Electron
chemical_list: D000911:Antibodies, Monoclonal; D005404:Fixatives; D005976:Glutaral