A computer simulation of the electrophoretic separation and detection of the isozymes of creatine kinase.
A program is described, written in BASIC for the Apple II + Computer, which allows for the simulation of a typical experiment in electrophoresis. The subject of the simulation is the separation and detection of the isozymes of creatine kinase, which are important in the diagnosis of several disorders, including myocardial infarction. The program allows the user to investigate the effects of several variables on electrophoretic mobility and includes simulations of isozyme patterns characteristic of specific pathological conditions.
D000818:Animals; D001921:Brain / Q000201:enzymology; D003201:Computers; D003402:Creatine Kinase / Q000097:blood / Q000302:isolation & purification*; D004586:Electrophoresis; D000882:Haplorhini; D006863:Hydrogen-Ion Concentration; D007527:Isoenzymes; D009132:Muscles / Q000201:enzymology; D011817:Rabbits; D012984:Software
D007527:Isoenzymes; D003402:Creatine Kinase