The TRH test in bulimia and anorexia nervosa: a controlled study.
TSH responsiveness to 500 micrograms TRH given intravenously was examined in ten bulimic outpatients, nine anorexic in-patients and a group of age matched healthy subjects. Serum TSH levels were measured by means of a sensitive radioimmune assay. There were no group differences between bulimic subjects and the healthy comparison group. Anorexic subjects at low weight showed a delayed response to TRH, which tended to normalize with weight gain. Bulimic subjects showed varied patterns of response and it remains possible that a sub-group of bulimic patients may have an abnormality of response to TRH.
D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000097:blood* / Q000175:diagnosis; D001835:Body Weight; D003866:Depressive Disorder / Q000097:blood / Q000175:diagnosis; D001068:Feeding and Eating Disorders / Q000097:blood*; D006801:Humans; D006963:Hyperphagia / Q000097:blood* / Q000175:diagnosis; D013972:Thyrotropin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone
D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin