[AMP-deaminase activity of circulating leukocytes in the human].
It is shown that the AMP-deaminase activity in leucocytes of the human peripheric blood in contrast with the enzyme from erythrocytes manifests its activity only if it is isolated in the presence of K+ or Na+ ions. Pi and GTP being inhibitors of the enzyme in different tissues including erythrocytes do not alter the AMP-deaminase activity in leucocytes. 3,3',5-triiodothyracetic acid markedly decreasing the AMP-deaminase activity of leucocytes does not affect the enzyme activity in the hemolyzate of erythrocytes. The results obtained have shown that the AMP-deaminase activity in leucocytes of the human peripheric blood possesses some regulatory properties differing from those of the enzyme in erythrocytes.
D000659:AMP Deaminase / Q000097:blood*; D000249:Adenosine Monophosphate / Q000378:metabolism; D000494:Allosteric Regulation; D004912:Erythrocytes / Q000201:enzymology; D006801:Humans; D066298:In Vitro Techniques; D007962:Leukocytes / Q000201:enzymology*; D009709:Nucleotide Deaminases / Q000097:blood*; D011188:Potassium / Q000378:metabolism
D000249:Adenosine Monophosphate; D009709:Nucleotide Deaminases; D000659:AMP Deaminase; D011188:Potassium
AMP-dezaminaznaia aktivnost' leĭkotsitov perifericheskoĭ krovi cheloveka.