[Multidisciplinary treatment of cancer of the pancreas].
During the past 18 and a half years, 285 patients with cancer of the pancreas have been treated in our hospital. By means of en-bloc resection of the lesion with the portal vein and/or hepatic artery, the resectable rate of cancer of the head of the pancreas was improved to 53% (1979-1983) from 22% (1966-1978). Postoperative deaths within 30 days after pancreatectomy were 9.8%. The five years survival rate in those with Stage I and II was 28.7%, but that with Stage III and IV was 15.2%. Intraoperative and/or external radiation therapy was adopted on 16 patients, in some of whom hyperthermia was further combined. As a result, remarkable effects on performance status were obtained. Intra-arterial infusion chemotherapy using a transfemorally implanted catheter was performed on ten patients with unresectable lesions, the median survival of whom was however, only four and a half months.
D000328:Adult; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D011882:Radiotherapy, High-Energy
D000903:Antibiotics, Antineoplastic; D008937:Mitomycins; D016685:Mitomycin