The coincidence of glucose-6-phosphate dehydrogenase deficiency and hemoglobin S gene in Cukurova Province, Turkey.
A total of 1,582 subjects from 10 villages of different ethnic populations were screened for glucose-6-phosphate dehydrogenase (G6PD) deficiency (GdB-, Mediterranean variant) and hemoglobin S gene, and the coincidence of both abnormalities was determined. Although the prevalence of both abnormalities was found to be highest in an Eti-Turk group living in the Tarsus area, coincidence was not significant. In a single village of Adana Eti-Turks, however, coincidence was found to be significant, although neither the frequency of G6PD deficiency nor the existence of hemoglobin S gene was highest in that village.
D000755:Anemia, Sickle Cell / Q000150:complications; D004586:Electrophoresis; D004812:Epidemiologic Methods; D005006:Ethnicity; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications / Q000453:epidemiology*; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006801:Humans; D008297:Male; D014421:Turkey
D006451:Hemoglobin, Sickle