Acetate versus bicarbonate hemodialysis in critically ill patients.
The hemodynamic state, acid-base balance and blood gases were studied in 9 acute renal failure patients during recirculation acetate- and bicarbonate dialysis. A significant hemodynamic instability, due to a decreased cardiac performance, was observed during acetate dialysis, whereas during bicarbonate dialysis, there was a stable hemodynamic state. During acetate dialysis, pO2 dropped significantly, due to a decreasing ventilatory drive as a consequence of the significantly lower pCO2 in acetate dialysis. From these findings, we conclude that bicarbonate dialysis should be the first choice in the treatment of acute renal failure patients.
D000085:Acetates; D000368:Aged; D001639:Bicarbonates; D001794:Blood Pressure; D002302:Cardiac Output; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D014655:Vascular Resistance
D000085:Acetates; D001639:Bicarbonates