Diphacinone-induced coagulopathy in the dog.
Five cases of coagulopathy caused by consumption of indanedione (diphacinone)-based rodenticides are reported. In each case, acute onset of lethargy and respiratory distress were the predominant initial clinical signs. Thoracic radiography revealed pulmonary edema, pleural effusion, and/or pericardial effusion as consistent findings. Laboratory evaluations confirmed coagulopathies that responded to vitamin K1 therapy.
D000818:Animals; D001778:Blood Coagulation Disorders / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000662:veterinary*; D004283:Dog Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D004285:Dogs; D005260:Female; D007189:Indans / Q000506:poisoning*; D007192:Indenes / Q000506:poisoning*; D008297:Male; D013902:Radiography, Thoracic / Q000662:veterinary
D007189:Indans; D007192:Indenes; C001445:1,3-indandione