Case report of two children with pseudohypoaldosteronism.
Two black male siblings with pseudohypoaldosteronism are reported. They became ill in infancy with failure to thrive, renal salt wasting, and marked elevation of plasma aldosterone. These two patients illustrate many features of this uncommon disorder, as well as a severe metabolic acidosis. To our knowledge, this is the first report of pseudohypoaldosteronism in a black family.
D000141:Acidosis, Renal Tubular / Q000175:diagnosis* / Q000178:diet therapy / Q000503:physiopathology; D000450:Aldosterone / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012964:Sodium / Q000008:administration & dosage
D000450:Aldosterone; D012964:Sodium