title: Proposed changes in DSM-III substance use disorders: description and rationale.
abstract: The authors describe changes in DSM-III substance use disorders to be included in the revised version, DSM-III-R. Major revisions include removal of the distinction between "abuse" and "dependence" and broadening the definition of "dependence" to a syndrome of clinically significant behaviors that indicate a serious degree of involvement with psychoactive drugs; creation of a new category of "psychoactive substance neuroadaptation syndrome" for individuals whose physiological adaptations to high doses of psychoactive substances did not arise from their own behavior; use of an identical set of symptoms and behaviors to determine dependence on all different classes of psychoactive substances; and provision of a system for rating severity of dependence.
mesh_terms: D004361:Drug Tolerance; D006801:Humans; D008370:Manuals as Topic / Q000592:standards*; D011619:Psychotropic Drugs / Q000009:adverse effects; D013375:Substance Withdrawal Syndrome / Q000145:classification / Q000175:diagnosis / Q000523:psychology; D019966:Substance-Related Disorders / Q000145:classification / Q000175:diagnosis* / Q000523:psychology; D009626:Terminology as Topic
chemical_list: D011619:Psychotropic Drugs