Treatment of meprobamate overdose with repeated oral doses of activated charcoal.
The use of repeated oral activated charcoal (ROAC) administration is reported in two patients who presented with acute meprobamate ingestions. Both patients had a measured meprobamate half-life of approximately 4.5 hours, the shortest reported in the literature. ROAC appears to be a safe, effective agent that may play a role in increasing the clearance of a number of agents from the systemic circulation. Further study in this area is needed.
D000284:Administration, Oral; D000328:Adult; D002606:Charcoal / Q000008:administration & dosage*; D004632:Emergency Medical Services; D005260:Female; D006207:Half-Life; D006801:Humans; D008620:Meprobamate / Q000506:poisoning*; D013406:Suicide, Attempted; D013607:Tablets; D013997:Time Factors
D013607:Tablets; D002606:Charcoal; D008620:Meprobamate