title: Can mutagenesis reveal major genes affecting senescence?
abstract: The Drosophila melanogaster genome was screened for sex-linked recessive and autosomal dominant mutations affecting the senescent decline in motor abilities. No persistent identifiable genes delaying the onset of senescence were recovered among 18,089 F1 male offspring of males exposed to radiation or the chemical mutagen, EMS.
mesh_terms: D000375:Aging; D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics; D005260:Female; D005796:Genes; D008297:Male; D009043:Motor Activity; D009154:Mutation