title: Influence of aeroallergens on bronchial reactivity in children sensitized to grass pollens.
abstract: Nine children, sensitized to grass pollens, with seasonal rhinitis and mild asthma underwent bronchial challenge with carbachol and EIA test repeatedly either during a pre-seasonal or in seasonal period. We failed to find any significant difference between pre-seasonal and seasonal values in both tests. We believe that atmospheric conditions are an important determinant of our results. It is our hypothesis that a threshold concentration in atmospheric pollen may exist which must be reached before an allergic reaction is evident.
mesh_terms: D000397:Air Pollution / Q000032:analysis*; D001249:Asthma / Q000276:immunology; D001980:Bronchi / Q000187:drug effects* / Q000276:immunology; D002217:Carbachol / Q000494:pharmacology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D011058:Pollen / Q000032:analysis* / Q000494:pharmacology
chemical_list: D002217:Carbachol