Evaluation of a clinically useful length of 1 mm diameter PTFE as a microvascular graft.
Previous studies of 1 mm internal diameter polytetrafluoroethylene (PTFE) have investigated short graft lengths. The aim of this experiment was to assess a longer, clinically useful graft. Femoro-femoral crossover grafts 6 cm long were implanted into 20 rats and, after an initial observation period of 1 hour, were followed up for four weeks. Ten grafts failed within the first hour post-operatively, one was occluded at 2 weeks and nine were patent at 4 weeks (45% patency). Technical errors causing stasis within the prosthesis led to the early failures. When stasis was avoided patency was good and did not appear to be dependent upon development of a cellular lining within the graft.
D000818:Animals; D001807:Blood Vessel Prosthesis; D005263:Femoral Artery / Q000601:surgery* / Q000648:ultrastructure; D006083:Graft Occlusion, Vascular / Q000209:etiology / Q000473:pathology; D008855:Microscopy, Electron, Scanning; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D011475:Prosthesis Failure; D051381:Rats; D013997:Time Factors
D011138:Polytetrafluoroethylene