Serum calcium fractions in essential hypertensive and matched normotensive subjects.
Concentrations of serum total calcium and serum calcium fractions were compared between 28 hypertensive subjects and 28 race-sex-age-matched normotensive controls. Mean levels of serum total calcium were not different between the two groups. Hypertensive subjects had lower mean serum levels of ultrafilterable calcium (-0.32 mg/dl; p = 0.01), ionized calcium (-0.07 mg/dl; p = 0.09), and complexed calcium (-0.23 mg/dl; p = 0.04) and higher levels of protein-bound calcium (+0.36 mg/dl; p = 0.07). Estimated dietary calcium intake was similar in the two groups. These findings add to the evidence that essential hypertension is associated with perturbations in calcium metabolism.
D000328:Adult; D000368:Aged; D002118:Calcium / Q000097:blood* / Q000502:physiology; D002136:Calcium, Dietary / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000503:physiopathology; D007477:Ions; D008297:Male; D008875:Middle Aged; D011485:Protein Binding; D014462:Ultrafiltration
D002136:Calcium, Dietary; D007477:Ions; D002118:Calcium