The association of penicillin-binding proteins with cell elongation and septum formation in Bacillus megaterium.
Analysis of the penicillin-binding proteins in the membranes from germinated spores of Bacillus megaterium and a filamentous mutant indicated that (a) no specific synthesis of any penicillin-binding protein occurred before or during two relatively synchronous cell divisions, (b) penicillin-binding proteins 1, 3a and 3b may be involved in cell elongation and (c) filamentation of the mutant may be due to a decrease in the concentration of penicillin-binding protein 1.
D001410:Bacillus megaterium / Q000166:cytology / Q000201:enzymology* / Q000502:physiology; D001426:Bacterial Proteins; D002268:Carboxypeptidases / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D002455:Cell Division; D002462:Cell Membrane / Q000201:enzymology; D004591:Electrophoresis, Polyacrylamide Gel; D006602:Hexosyltransferases; D002267:Muramoylpentapeptide Carboxypeptidase / Q000378:metabolism*; D010400:Penicillin G / Q000378:metabolism; D046915:Penicillin-Binding Proteins; D010458:Peptidyl Transferases; D013171:Spores, Bacterial / Q000378:metabolism
D001426:Bacterial Proteins; D002352:Carrier Proteins; D046915:Penicillin-Binding Proteins; D010458:Peptidyl Transferases; D006602:Hexosyltransferases; D002268:Carboxypeptidases; D002267:Muramoylpentapeptide Carboxypeptidase; D010400:Penicillin G