[Azo derivatives of levorin].
Levorin, an aromatic heptaenic antibiotic and sodium nitrite in solution of acetic acid formed a diazo compound. In the diazo reaction this compound interacted with beta-napthol or H-acid. The resulting azo compounds were readily soluble in organic solvents. In water their nitrites formed true solutions. The biological activity of the azo levorins was 100-200 times lower than that of the initial levorin. The physico-chemical characteristics of the azo levorins are presented.
D000935:Antifungal Agents / Q000494:pharmacology*; D002174:Candicidin / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000494:pharmacology*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005658:Fungi / Q000187:drug effects; D008722:Methods; D012995:Solubility; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D002174:Candicidin
Azoproizvodnye levorina.