title: DNA metabolism during infection of Anacystis nidulans by cyanophage AS-1. VII. UV-induced alterations of the AS-1/A. nidulans lytic cycle.
abstract: In order to interfere specifically with either the host of phage DNA metabolism and separate the effects of new phage DNA synthesis from the effects of host cell breakdown and PIL-DNA formation, UV irradiation of either the host, A. nidulans, or intact phage AS-1, prior to infection was utilized. Several conclusions were reached. First, a photoreactivation system was present in UV-irradiated A. nidulans. Second, the complete burst size of AS-1 was severely affected by UV irradiation of cells and/or phage; third, UV treatment of cells infected with healthy phage caused an early release of phage at 12 h instead of 16 h post-infection; however, healthy cells infected with UV-irradiated phage caused a delayed release of phage as 20 h.
mesh_terms: D000458:Cyanobacteria / Q000378:metabolism / Q000528:radiation effects*; D004247:DNA / Q000378:metabolism*; D003624:Darkness; D008027:Light; D013997:Time Factors; D014466:Ultraviolet Rays; D010948:Viral Plaque Assay; D014780:Viruses / Q000254:growth & development / Q000378:metabolism / Q000528:radiation effects*
chemical_list: D004247:DNA