Aldehyde dehydrogenase polymorphism in North American, South American, and Mexican Indian populations.
While about 40% of the South American Indian populations (Atacameños, Mapuche, Shuara) were found to be deficient in aldehyde dehydrogenase isozyme I (ALDH2 or E2), preliminary investigations showed very low incidence of isozyme deficiency among North American natives (Sioux, Navajo) and Mexican Indians (mestizo). Possible implications of such trait differences on cross-cultural behavioral response to alcohol drinking are discussed.
D000444:Aldehyde Dehydrogenase / Q000172:deficiency / Q000235:genetics*; D002677:Chile; D004484:Ecuador; D006197:Hair / Q000201:enzymology; D006801:Humans; D007198:Indians, North American; D007199:Indians, South American; D007527:Isoenzymes / Q000172:deficiency / Q000235:genetics*; D008800:Mexico; D009516:New Mexico; D009658:North Dakota; D011110:Polymorphism, Genetic
D007527:Isoenzymes; D000444:Aldehyde Dehydrogenase