Three cases of preleukemic myelodysplastic disorders with the same translocation t(1;3).
The same translocation, t(1;3)(p36;q21), was observed in three patients with a preleukemic syndrome presenting as a myelodysplastic disorder. It was the only chromosomal abnormality in two patients; and the third patient had 12p- and 15q- as additional abnormalities. The three cases evolved into acute nonlymphocytic leukemia.
D000328:Adult; D000368:Aged; D002900:Chromosomes, Human, 1-3; D005260:Female; D006801:Humans; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D011289:Preleukemia / Q000235:genetics*; D014178:Translocation, Genetic