The amino acid sequence of the zinc-requiring beta-lactamase II from the bacterium Bacillus cereus 569.
The amino acid sequence of the zinc-requiring beta-lactamase II from Bacillus cereus strain 569 has been determined. It consists of a single polypeptide chain of 227 residues. It is the only example so far fully characterized of a class B beta-lactamase, and is structurally and mechanistically distinct from both the widely distributed class A beta-lactamases (such as the Escherichia coli RTEM enzyme) and from the chromosomally encoded class C enzymes from Gram-negative bacteria.
D000595:Amino Acid Sequence; D001409:Bacillus cereus / Q000201:enzymology*; D002510:Cephalosporinase / Q000032:analysis*; D003488:Cyanogen Bromide / Q000494:pharmacology; D010446:Peptide Fragments / Q000032:analysis; D015032:Zinc / Q000378:metabolism*; D001618:beta-Lactamases / Q000032:analysis*
D010446:Peptide Fragments; D002510:Cephalosporinase; D001618:beta-Lactamases; D015032:Zinc; D003488:Cyanogen Bromide