A case of phenytoin toxicity possibly precipitated by trazodone.
A case of phenytoin toxicity associated with the use of trazodone is described. Interaction between these drugs has not been reported previously. More frequent monitoring of serum phenytoin levels may be needed in patients who are concomitantly receiving trazodone.
D000328:Adult; D004244:Dizziness / Q000139:chemically induced; D004347:Drug Interactions; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000097:blood / Q000494:pharmacology / Q000633:toxicity*; D012563:Schizophrenia, Paranoid / Q000150:complications / Q000188:drug therapy; D012640:Seizures / Q000150:complications / Q000188:drug therapy; D014196:Trazodone / Q000494:pharmacology* / Q000627:therapeutic use
D010672:Phenytoin; D014196:Trazodone