title: Treatment of meprobamate overdose with repeated oral doses of activated charcoal.
abstract: The use of repeated oral activated charcoal (ROAC) administration is reported in two patients who presented with acute meprobamate ingestions. Both patients had a measured meprobamate half-life of approximately 4.5 hours, the shortest reported in the literature. ROAC appears to be a safe, effective agent that may play a role in increasing the clearance of a number of agents from the systemic circulation. Further study in this area is needed.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D002606:Charcoal / Q000008:administration & dosage*; D004632:Emergency Medical Services; D005260:Female; D006207:Half-Life; D006801:Humans; D008620:Meprobamate / Q000506:poisoning*; D013406:Suicide, Attempted; D013607:Tablets; D013997:Time Factors
chemical_list: D013607:Tablets; D002606:Charcoal; D008620:Meprobamate