8;14 chromosome translocation in a negative bone marrow aspirate from a patient with Burkitt's lymphoma.
A patient with Burkitt's lymphoma is described who, on presentation, had a bone marrow aspirate which did not show abnormal cells. Cells from the bone marrow were cultured and an 8;14 chromosome translocation was identified. This finding allowed us to upgrade the stage of disease from III to IV with therapeutic as well as prognostic implications.
D001853:Bone Marrow / Q000473:pathology / Q000648:ultrastructure*; D002051:Burkitt Lymphoma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D002648:Child; D002901:Chromosomes, Human, 13-15; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D014178:Translocation, Genetic