[Role of additional substrates in DDT degradation by cultures of Pseudomonas aeruginosa].
The activity of enzymes was compared during Pseudomonas aeruginosa 640x growth on compounds activating DDT to a different degree and on acetate which did not stimulate this process. The activity of dehydrogenases generating reduced cofactors necessary for DDT dechlorination was found to be much higher on effective additional substrates than on compounds which either had no effect on DDT degradation or stimulated this process only slightly. The activity of enzymes generating the reduced cofactors was shown to correlate with the extent of DDT degradation by this culture.
D000085:Acetates / Q000494:pharmacology; D000473:Alkanes / Q000494:pharmacology; D001673:Biodegradation, Environmental; D003634:DDT / Q000378:metabolism*; D000431:Ethanol / Q000494:pharmacology; D005947:Glucose / Q000494:pharmacology; D005990:Glycerol / Q000494:pharmacology; D010088:Oxidoreductases / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000378:metabolism*; D012266:Ribose / Q000494:pharmacology
D000085:Acetates; D000473:Alkanes; D000431:Ethanol; D012266:Ribose; D003634:DDT; D010088:Oxidoreductases; C007932:n-hexadecane; D005947:Glucose; D005990:Glycerol
Izuchenie roli dopolnitel'nykh substratov pri degradatsii DDT kul'turoĭ Pseudomonas aeruginosa.