[Cure of osteopetrosis by injection of allogenic bone marrow into "op" rats treated with cyclosporin A].
The cure of osteopetrosis by allogenic bone marrow injection has been obtained in "op" mutant rat kept under cyclosporin A treatment. This immunosuppressive agent able to prevent the rejection of transplanted cells does not impair the propriety of these cells to restore the bone resorption process in this severe osteopetrotic form.
D000818:Animals; D016026:Bone Marrow Transplantation; D003524:Cyclosporins / Q000627:therapeutic use*; D010022:Osteopetrosis / Q000000981:diagnostic imaging / Q000628:therapy*; D011859:Radiography; D051381:Rats; D011922:Rats, Mutant Strains
D003524:Cyclosporins
Guérison de l'ostéopétrose par injection de moelle osseuse allogénique chez le rat "op" traité par la cyclosporine A.