Retrograde trypsin instillation into the renal pelvis for the dissolution of obstructive blood clots.
A case of heavy hematuria after renal biopsy causing retention of blood clots and obstruction of the renal pelvis is reported. The blood clots were successfully lysed by retrograde ureteral instillation of crystalline trypsin (Trypure) without any signs of harmful effects on the renal parenchyma.
D000328:Adult; D001707:Biopsy, Needle / Q000009:adverse effects; D002404:Catheterization; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy* / Q000209:etiology; D007682:Kidney Pelvis / Q000000981:diagnostic imaging; D008297:Male; D007507:Therapeutic Irrigation; D013927:Thrombosis / Q000188:drug therapy* / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014357:Trypsin / Q000008:administration & dosage* / Q000627:therapeutic use
D014357:Trypsin