Intraocular acyclovir levels after subconjunctival and topical administration.
Substantial levels of acyclovir were detected in the aqueous and vitreous of New Zealand rabbits at various time intervals following subconjunctival injection. Intravitreal penetration of acyclovir after topical application was poor.
D000212:Acyclovir / Q000008:administration & dosage / Q000378:metabolism*; D000287:Administration, Topical; D000818:Animals; D001082:Aqueous Humor / Q000378:metabolism; D007267:Injections; D011817:Rabbits; D014822:Vitreous Body / Q000378:metabolism
D000212:Acyclovir