title: [Basic and clinical studies on cefminox in the field of obstetrics and gynecology].
abstract: Basic and clinical studies were carried out on cefminox (CMNX, MT-141), a new cephem antibiotic. Results obtained were as follows. Following each 1 g of intravenous drip infusion and intravenous injection, transfer of CMNX to the internal genital organs was good. Transfer of CMNX into exudate of the pelvic dead space was also good and showed high concentration. CMNX was given to 2 cases. Clinical efficacy was good in 1 case, and could not be evaluated in 1 case. No side effects were observed in both cases. The above results show that CMNX is an effective agent.
mesh_terms: D000328:Adult; D002513:Cephamycins / Q000097:blood / Q000378:metabolism / Q000627:therapeutic use*; D004716:Endometritis / Q000188:drug therapy* / Q000378:metabolism; D005122:Exudates and Transudates / Q000378:metabolism; D005260:Female; D006801:Humans; D007700:Kinetics; D010053:Ovary / Q000378:metabolism; D010249:Parametritis / Q000188:drug therapy* / Q000378:metabolism; D014599:Uterus / Q000378:metabolism
chemical_list: D002513:Cephamycins; C046079:cefminox