Naloxone and propranolol inhibit the disruption of the hippocampal theta waves induced by D-lysergic acid diethylamide in the rabbit.
In the rabbit, naloxone and propranolol antagonize the disruption of the hippocampal theta waves induced by LSD. These results are discussed in view of the reported effects of these drugs in curing hallucinatory symptoms in mentally disturbed patients.
D000818:Animals; D004569:Electroencephalography; D006624:Hippocampus / Q000187:drug effects*; D008238:Lysergic Acid Diethylamide / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology*; D011817:Rabbits; D013826:Theta Rhythm
D009270:Naloxone; D008238:Lysergic Acid Diethylamide; D011433:Propranolol