[Pharmacokinetics of 113mIn-indifor].
113mIn-indifor pharmacokinetics was studied in 82 patients with malignant tumors (breast and lung carcinoma, reticulum cell sarcoma) in the first 2 hrs after i. v. injection. The drug redistribution in the first minutes occurred mainly between the osseous tissue and the urinary system, the value of radioactivity in the urinary bladder by the 1st hour was 50% of the injected value making it possible to visualize the kidneys. A high gradient of the drug accumulation in the osseous tissues and the adjacent organs and tissues made it possible to obtain high quality scintigrams. Radiation exposure of the skeleton was 7.0 mu Gy/MBq, that of the urinary bladder 61 mu Gy/MBq.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007204:Indium / Q000378:metabolism*; D007554:Isotopes; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D014018:Tissue Distribution
D007554:Isotopes; D007204:Indium
Farmakokinetika indifora 113mIn.