Electroretinographic findings in selected pedigrees with choroideremia.
We recorded full-field electroretinograms from 47 males and 26 obligate carrier females with choroideremia. All males had responses that were subnormal with delayed cone b-wave implicit times or undetectable. Only four of 26 females had abnormal electroretinographic responses but 25 of 26 were identified by ophthalmoscopy.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002353:Carrier State / Q000503:physiopathology; D002648:Child; D002829:Choroid; D004596:Electroretinography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010786:Photoreceptor Cells / Q000503:physiopathology; D014603:Uveal Diseases / Q000235:genetics* / Q000503:physiopathology