title: Theoretical and experimental aspects of the possible role of calcium in some physiological and physiopathological phenomena.
abstract: The role played by calcium in some physiological and physiopathological phenomena is examined in the light of the intervention of calmodulin as a calcium regulatory protein. Data are presented concerning the interaction of some heavy metal ions with the erythrocyte membrane with special references to the modifications of calcium dynamics by Pb2. The results are discussed considering the interaction of heavy metal ions with the proteins of erythrocyte cytoskeleton and the role played by calmodulin in this interaction.
mesh_terms: D001777:Blood Coagulation; D002118:Calcium / Q000502:physiology*; D002147:Calmodulin / Q000502:physiology; D004347:Drug Interactions; D004798:Enzymes / Q000502:physiology; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007854:Lead / Q000494:pharmacology; D008954:Models, Biological
chemical_list: D002147:Calmodulin; D004798:Enzymes; D007854:Lead; D002118:Calcium