[Action of medazonamid on cough in an experiment].
The anti-cough effect of medazonamide was studied on 40 nonanesthetized cats. The cough was induced by mechanical irritation of the laryngopharyngeal and tracheobronchial mucous of the respiratory tract. It was shown that the intraabdominal administration of medazonamide in 5, 10 and 20 mg/kg doses has less anti-cough effect than codeine in the given conditions.
D000818:Animals; D000996:Antitussive Agents / Q000627:therapeutic use*; D002415:Cats; D003061:Codeine / Q000627:therapeutic use; D003371:Cough / Q000188:drug therapy* / Q000209:etiology; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005260:Female; D008297:Male; D008365:Manometry; D010812:Physical Stimulation / Q000379:methods; D011724:Pyridazines / Q000627:therapeutic use*; D013997:Time Factors
D000996:Antitussive Agents; D011724:Pyridazines; C048087:medazomide; D003061:Codeine
Vozdeĭstvie medazonamida na kashel' v éksperimente.