4-Dimethylaminophenol and dicobalt edetate (Kelocyanor) in the treatment of experimental cyanide poisoning.
The efficacy of dicobalt edetate (Kelocyanor) was compared against that of 4-dimethylaminophenol (DMAP) in experimental cyanide poisoning. DMAP gave better survival. The efficacy has been related to the toxicity of the two compounds.
D000627:Aminophenols / Q000494:pharmacology*; D000818:Animals; D000931:Antidotes; D003486:Cyanides / Q000097:blood / Q000506:poisoning*; D004285:Dogs; D004492:Edetic Acid / Q000494:pharmacology*; D005260:Female; D008708:Methemoglobinemia / Q000139:chemically induced; D013997:Time Factors
D000627:Aminophenols; D000931:Antidotes; D003486:Cyanides; C028222:cobalt-ethylenediamine tetraacetic acid chelate; D004492:Edetic Acid; C020292:4-dimethylaminophenol