title: [Cefpirome (HR 810). A new broad spectrum cephalosporin].
abstract: HR 810 or cefpirome is a new 2-amino-thiazol cephalosporin whose salient characteristic is a bicyclic nucleus, namely cyclopenteno-pyridinium, in position 3. This nucleus imparts a broad spectrum of activity that includes Enterobacteriaceae, Staphylococcus aureus, Pseudomonas aeruginosa, Neisseria, non-D Streptococcus and Haemophilus. Cefpirome is also active, although to a lesser extent, against Streptococcus faecalis and Acinetobacter.
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D002511:Cephalosporins / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D004755:Enterobacteriaceae / Q000187:drug effects; D013293:Enterococcus faecalis / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship; D000097572:Cefpirome
chemical_list: D002511:Cephalosporins; D000097572:Cefpirome
vernacular_title: Cefpirome (HR 810). Une nouvelle céphalosporine à large spectre.