Ontogeny of J chain expression in pig lymphocytes.
The ontogeny of lymphocytes expressing J chain in the cytoplasm (J+) was studied in pig foetuses by the immunofluorescent technique. Peripheral blood lymphocytes were the first J+ cells in prenatal life. The spleen and lymph nodes contained J+ cells in the last days of gestation. J+ cells were found in the lamina propria of the gut and some glands of conventional but not of germ-free piglets. J chain was not detected on or in cell membranes at any developmental stage.
D000818:Animals; D005333:Fetus / Q000276:immunology; D005455:Fluorescent Antibody Technique; D005856:Germ-Free Life; D005865:Gestational Age; D007144:Immunoglobulin J-Chains / Q000096:biosynthesis*; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D013552:Swine / Q000276:immunology*
D007144:Immunoglobulin J-Chains