Counterion distribution around DNA: variation with conformation and sequence.
The three-dimensional Poisson-Boltzmann equation for the distribution of counterion charge density around double helical DNA has been solved by an iterative procedure. These computations have been performed for 0.01M monovalent salt solutions. A systematic study of the ten possible sequences found among adjacent nucleotide base pairs is presented for the A, B, and C conformations of DNA. In addition, calculations of the electrostatic stabilities of these conformations of DNA allows for comparison of the charge accumulation around each of the three conformers.
D001483:Base Sequence; D004247:DNA; D007477:Ions; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D013329:Structure-Activity Relationship; D013816:Thermodynamics; D014867:Water
D007477:Ions; D014867:Water; D004247:DNA