Naltrexone blocks the post-shock increase of ethanol consumption.
Attention has recently focused on the possibility of an interaction between ethanol and the endorphin system. In this study the opiate blocker naltrexone prevents the expected post-shock increase of ethanol consumption. This provides further evidence that endogenous opiates are involved in the voluntary drinking of ethanol in rats.
D000428:Alcohol Drinking / Q000187:drug effects*; D000818:Animals; D004597:Electroshock; D008297:Male; D009271:Naltrexone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012054:Reinforcement, Psychology
D009271:Naltrexone