Amine N-methyltransferases from rabbit liver.
N-Methylation of amines has been ascribed to enzymes listed as amine N-methyltransferase, indolethylamine N-methyltransferase, and arylamine N-methyltransferase. All of these activities are accomplished by each of two related enzymes present in rabbit liver. The two N-methyltransferases have a very broad and overlapping specificity for primary and secondary amines. Both have a molecular mass of 30,000 daltons and react with an antibody formed to one of them, but have different isoelectric points.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D007526:Isoelectric Point; D007527:Isoenzymes / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008780:Methyltransferases / Q000302:isolation & purification*; D008970:Molecular Weight; D011817:Rabbits; D014363:Tryptamines / Q000378:metabolism
D000596:Amino Acids; D007527:Isoenzymes; D014363:Tryptamines; C030820:tryptamine; D008780:Methyltransferases; C033552:tryptamine N-methyltransferase