title: Correlation of a disease scoring system with arterial PO2 values in respiratory syncytial virus infection in calves.
abstract: The mean arterial PO2 value measured in blood obtained by puncture of the brachial artery of 20 calves with acute clinical signs of a bovine respiratory syncytial virus (BRSV) infection was 8.4 +/- 1.9 kPa. The values differed significantly from arterial PO2 values of eleven healthy calves (mean 14.2 +/- 1.5 kPa). A disease scoring system is presented based on the type of respiration and the findings on auscultation. A high correlation (r = -0.87) was found between disease scores and arterial PO2 values. This indicates that the described disease scoring system can be a useful tool in the evaluation of the severity and course of BRSV infections in calves, and could be used for evaluating the efficacy of BRSV vaccines in the field. The course of disease was studied in 127 calves with clinical signs of serologically proven BRSV infection. Animals with mild respiratory signs during the acute phase of disease remained free of severe respiratory problems until the end of a 35-day examination period. Mean disease scores indicated that animals with severe signs in the acute phase often developed persistent respiratory problems.
mesh_terms: D000818:Animals; D001314:Auscultation / Q000662:veterinary; D001784:Blood Gas Analysis / Q000662:veterinary; D002245:Carbon Dioxide / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood* / Q000503:physiopathology; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure; D012135:Respiratory Sounds / Q000145:classification; D012136:Respiratory Syncytial Viruses; D010253:Respirovirus Infections / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen