Well-compensated primary bile acid malabsorption presenting as chronic nonspecific diarrhea.
Increased fecal bile acid loss and defective in vitro ileal bile acid uptake were demonstrated in an 8-year-old boy with diarrhea starting in the neonatal period. His continuously normal physical development and good nutritional status are in keeping with a well-preserved cholic acid pool and normal duodenal bile acid concentration. Isolated bile acid malabsorption can remain well compensated and present as the chronic nonspecific diarrhea syndrome of childhood.
D001647:Bile Acids and Salts / Q000378:metabolism*; D002648:Child; D002908:Chronic Disease; D003967:Diarrhea / Q000209:etiology* / Q000378:metabolism; D005243:Feces / Q000032:analysis; D006801:Humans; D007408:Intestinal Absorption; D008286:Malabsorption Syndromes / Q000150:complications* / Q000378:metabolism; D008297:Male
D001647:Bile Acids and Salts