Clinical presentation as a predictor of laparotomy findings in supradiaphragmatic stage I and II Hodgkin's disease.
Clinical presenting features, sex and histology have been correlated with laparotomy findings in 225 patients with clinical Stage I and II supradiaphragmatic Hodgkin's disease seen at The Royal Marsden Hospital between 1970 and 1979. Age, sex, and in Stage I disease, size and position of involved nodes were independent predictors of positive laparotomy. On the basis of these observations low risk (less than 15% positive laparotomy), high risk (greater than 50%) and intermediate risk categories can be defined. The observations form the basis of a policy employing laparotomy on a selective basis.
D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007813:Laparotomy; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012306:Risk; D012737:Sex Factors; D013223:Statistics as Topic