title: Lung dose corrections for 6- and 15-MV x rays.
abstract: We have measured the radiation dose in simple heterogeneous phantoms and compared our results with those obtained by various methods of computation. Dose data were obtained both within and distal to simulated regions of lung in order to test the ratio of tissue-air ratios (TAR), Batho, and equivalent TAR methods. These procedures are used routinely in manual and computer-aided planning of radiation therapy, but have been validated primarily for cobalt-60 radiation. Tests performed with 6- and 15-MV x rays reveal that incorrect doses can be computed within or near to a low-density medium, particularly when the field size is small. In these cases, electronic equilibrium is not achieved in the lateral direction, thereby violating an implicit assumption of all the above calculation methods. We quantify the errors in dose calculation for simple slab phantoms, and support our interpretation with a Monte Carlo simulation in which the energy transported by charged particles away from sites of x-ray interactions is considered directly.
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008168:Lung / Q000528:radiation effects*; D008954:Models, Biological; D008961:Models, Structural; D011829:Radiation Dosage; D011882:Radiotherapy, High-Energy; D014965:X-Rays