[Dependence of the degree of antibacterial and antiphage action of ozone on cell and phage particle concentrations in nutrient media].
The work was aimed at studying the inactivating effect of ozone on Escherichia coli K-12 AB1157, Pseudomonas aeruginosa PA01, Erwinia herbicola EH103 and their phages T4, SM and I4. The degree of bacterial and phage inactivation was found to increase with a decrease in their initial concentration during the treatment. The effect depends on differences in the quantity of ozone per cell or per phage particle in the reaction medium. This conclusion is based on the fact that, irrespective of the suspension density, the amount of surviving bacteria and phages plotted versus O3 concentration and recalculated per one bacterial cell or phage particle is described graphically by one and the same curve typical of a strain under study. This technique for assessing the sensitivity of microbiological objects to ozone can be used in order to compare experimental data obtained in different laboratories.
D001419:Bacteria / Q000187:drug effects*; D001435:Bacteriophages / Q000187:drug effects*; D003090:Coliphages / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004885:Erwinia / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007700:Kinetics; D010126:Ozone / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013997:Time Factors
D010126:Ozone
Zavisimost' stepeni antibakterial'nogo i antifagovogo deĭstviia ozona ot kontsentratsii kletok i fagovykh chastits v pitatel'noĭ srede.