title: Giant congenital cellular blue nevus of the scalp of a newborn with an underlying skull defect and invasion of the dura mater.
abstract: A case of a giant congenital cellular blue nevus of the scalp of a newborn with focal areas of malignant melanoma is presented. The nevus was associated with focal invasion of the underlying soft tissues, calvarium, epidural space, and dura mater. The later appearance of pigmented nevi in the submandibular region, sternocleidomastoid muscle, and testicular hydrocele raises the question of future metastases despite the nonmalignant microscopic appearance. Therapy consisted of total excision with cranioplasty and rotation and split skin grafts after temporary closure with silicone mesh.
mesh_terms: D004388:Dura Mater / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008545:Melanoma / Q000151:congenital / Q000473:pathology / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D009508:Nevus, Pigmented / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D011859:Radiography; D012535:Scalp / Q000002:abnormalities; D012888:Skull Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery