title: Treatment of cervical intraepithelial neoplasia with the carbon dioxide laser.
abstract: Between 1978 and 1983, one hundred and forty-six patients with CIN I-III were treated with the carbon dioxide laser and 129 have been followed for 6 to 58 months. The remission rate was 92.2% after one treatment and 98.4% after two treatments. All persistent lesions were detected within 8 weeks after treatment. After confirmation of remission, 4 patients (3.1%) developed recurrence of CIN at an average of 37 months after treatment. The CO2 laser therapy is safe, effective, and cost saving for the patient, but a certain rate of recurrence is to be expected and the necessity of a long-term follow-up is stressed.
mesh_terms: D000328:Adult; D002245:Carbon Dioxide; D002278:Carcinoma in Situ / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*
chemical_list: D002245:Carbon Dioxide