Effects of ovine prolactin on calcium uptake and distribution in Oreochromis mossambicus.
Ovine prolactin stimulated the net uptake rate of Ca2+ from the water by 96%, produced frank hypercalcemia, and increased total bone calcium content in fed rapidly growing freshwater male tilapia, Oreochromis mossambicus. It did not, however, alter the size of the readily exchangeable bone calcium pool. The increase in calcium accumulation resulted from an increase in whole-body Ca2+ influx and a decrease in Ca2+ efflux. It is concluded that prolactin exerts an important control over Ca2+ exchange between the fish and its environment and that through its hypercalcemic action prolactin indirectly facilitates bone mineralization.
D000818:Animals; D001834:Body Water / Q000378:metabolism; D001835:Body Weight; D001842:Bone and Bones / Q000378:metabolism; D002118:Calcium / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D008297:Male; D011388:Prolactin / Q000494:pharmacology*; D012756:Sheep; D014018:Tissue Distribution
D011388:Prolactin; D002118:Calcium