The critical micelle concentration of some physiologically important fatty acyl-coenzyme A's as a function of chain length.
The critical micelle concentration (CMC) of a series of saturated fatty acyl-CoAs have been determined using a fluorescent titration method with 2-toluidinylnaphthalene-6-sulfonate as a probe. The CMC was found to be a function of the number of carbon atoms in the acyl chain over the range tested (12 to 18). A double bond has the effect on the CMC of decreasing the acyl chain by 1.6 carbon atoms. Knowledge that the CMC of each of these fatty acyl-CoAs is a function of the acyl chain length and the availability of a simple and appropriate method for the estimation of this property under other conditions should be of importance in designing and interpreting in vitro experiments with these compounds.
D000214:Acyl Coenzyme A; D055598:Chemical Phenomena; D002621:Chemistry; D008823:Micelles; D012997:Solvents; D013050:Spectrometry, Fluorescence
D000214:Acyl Coenzyme A; D008823:Micelles; D012997:Solvents