Antigenic and biological characterization of avian paramyxovirus type 1 isolates from pigeons.
21 A/PMV-1 viruses were isolated from pigeons and characterized using polyclonal and monoclonal antisera in hemagglutination inhibition, seroneutralization and immunoprecipitation studies. Polyclonal and monoclonal antibodies directed against the HN and F proteins of Italien virus reacted with all pigeon isolates showing a close relationship between chicken velogenic and pigeon viruses. Differences in the M.W. of F0, P and M proteins were however observed between pigeon and chicken Italien virus. Marked differences in virulence were recorded among pigeon isolates; these were reflected by great variation in the IVPI of the different strains.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000956:Antigens, Viral / Q000032:analysis*; D001715:Bird Diseases / Q000382:microbiology*; D011232:Chemical Precipitation; D002645:Chickens; D010856:Columbidae / Q000382:microbiology*; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel; D015707:HN Protein; D008970:Molecular Weight; D010252:Paramyxoviridae / Q000276:immunology* / Q000472:pathogenicity; D014759:Viral Envelope Proteins / Q000276:immunology; D014764:Viral Proteins / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D015707:HN Protein; D014759:Viral Envelope Proteins; D014764:Viral Proteins