title: End-tidal CO2 as a guide to successful cardiopulmonary resuscitation: a preliminary report.
abstract: Utilizing a well-established porcine model of cardiac arrest, we found that end-tidal CO2 concentration (ETCO2) strikingly decreased to approximately 24% of control levels, immediately after cardiac arrest and before precordial compression. During precordial compression, ETCO2 progressively increased to 46% of control values in successfully resuscitated animals but only to 26% in animals which failed to respond to resuscitation efforts. After successful resuscitation, ETCO2 rapidly returned to baseline values. These data indicate that ETCO2 may be a useful monitor for assessing the adequacy of CPR.
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000032:analysis*; D006323:Heart Arrest / Q000503:physiopathology / Q000628:therapy*; D008991:Monitoring, Physiologic / Q000379:methods*; D012151:Resuscitation; D013552:Swine; D013990:Tidal Volume
chemical_list: D002245:Carbon Dioxide