title: Quantitative determination of nitroglycerin in human plasma by capillary gas chromatography with electron-capture detection.
abstract: A sensitive method for the selective determination of nitroglycerin at concentrations down to 50 pg/ml in human plasma is described. After the addition to plasma of a known amount of butane-1,2,4-triol trinitrate as internal standard, both compounds are extracted into hexane. Nitroglycerin is then quantitated by capillary gas chromatography with electron-capture detection.
mesh_terms: D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D006586:Hexanes; D006801:Humans; D005996:Nitroglycerin / Q000097:blood*
chemical_list: D006586:Hexanes; D005996:Nitroglycerin