title: Diurnal rhythm in the human rod ERG. Relationship to cyclic lighting.
abstract: Five normal subjects were monitored with periodic full-field ERG testing during entrainment to a 14L:10D lighting cycle. On the second day of entrainment, mean ERG threshold was significantly higher 1.5 hr after light onset than at other times of day and was comparable to a previously reported threshold elevation following 7 days of entrainment. This diurnal rhythm was not detectable in eyes entrained for 3 days that were then maintained in darkness for 1 day. The findings support the idea that 2 days of entrainment are required to maximize the diurnal rhythm in the human rod ERG and that an adapting light may be required to trigger this rhythm.
mesh_terms: D000221:Adaptation, Ocular; D000293:Adolescent; D000328:Adult; D002940:Circadian Rhythm; D003624:Darkness; D004596:Electroretinography; D006801:Humans; D008027:Light; D010786:Photoreceptor Cells / Q000502:physiology* / Q000503:physiopathology; D012160:Retina / Q000503:physiopathology; D012174:Retinitis Pigmentosa / Q000503:physiopathology; D013997:Time Factors