Common variable hypogammaglobulinemia in pregnancy: treatment with high-dose immunoglobulin infusions.
Pregnancy outcomes when the mother has common variable hypogammaglobulinemia are poor unless immunoglobulin levels are returned to normal or near-normal range. Intravenous immunoglobulin infusions are the favored mode of therapy. Here, we report the fifth patient so treated. Weekly doses of 200 mg/kg during the third trimester were required. A healthy term baby was delivered and the postpartum course was uncomplicated.
D000293:Adolescent; D000361:Agammaglobulinemia / Q000628:therapy*; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*