Burkitt-like lymphoma in a hemophilic boy with impaired cellular immunity.
Burkitt-like lymphoma was seen in a hemophilic boy with impaired cell-mediated immunity, of the type described in healthy hemophiliacs. The coexistence of two rare diseases, hemophilia and Burkitt's lymphoma in an immunosuppressed patient is suggestive of a blood-borne agent transmitted with factor VIII concentrates which might be an immune modifier and/or oncogenic at the same time.
D000008:Abdominal Neoplasms / Q000276:immunology*; D002051:Burkitt Lymphoma / Q000276:immunology*; D002675:Child, Preschool; D005169:Factor VIII / Q000627:therapeutic use; D006467:Hemophilia A / Q000150:complications* / Q000628:therapy; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000276:immunology; D008297:Male
D005169:Factor VIII