[Beta-glucosidases. Molecular bases of Gaucher's disease].
The first part of this review deals the biochemical data concerning human and mammalian beta-glucosidases. Glucosylceramide-beta-glucosidase and non-specific beta-glucosidase are characterized following their physical, functional, structural and genetical properties. The second part deals with the biochemical and pathophysiological data concerning the Gaucher disease.
D000818:Animals; D002460:Cell Line; D055598:Chemical Phenomena; D002621:Chemistry; D004195:Disease Models, Animal; D004789:Enzyme Activation; D005260:Female; D005776:Gaucher Disease / Q000175:diagnosis / Q000201:enzymology*; D005959:Glucosidases / Q000378:metabolism*; D005962:Glucosylceramidase / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D011247:Pregnancy; D011296:Prenatal Diagnosis; D001617:beta-Glucosidase / Q000235:genetics / Q000378:metabolism* / Q000502:physiology
D007527:Isoenzymes; D005959:Glucosidases; D001617:beta-Glucosidase; D005962:Glucosylceramidase
Beta-glucosidases. Bases moléculaires de la maladie de Gaucher.