[Sensitivity of grey and beige Djungarian hamsters to the blastomogenic action of 7,12-dimethylbenz(a)anthracene and 3-methylcholanthrene].
Sensitivity of normal gray and mutant beige (pink-eyed dilution mutation) Djungarian hamsters to the carcinogenic activity of 7,12-dimethylbenz (a) anthracene (DMBA) and 3-methylcholanthrene (MC) was studied. No differences between these two groups of animals which were given pills with DMBA were revealed. At the same time the beige females were found to be more sensitive to MC than males and hamsters of wild (gray) colour. Among tumours induced both by DMBA and MC fibrosarcomas prevailed both in the gray and beige hamsters. Fibrous histiocytomas were detected only in the MC-infected hamsters. Epithelial tumours were found only in females.
D015127:9,10-Dimethyl-1,2-benzanthracene / Q000633:toxicity*; D000818:Animals; D006224:Cricetinae; D005260:Female; D008297:Male; D008748:Methylcholanthrene / Q000633:toxicity*; D009154:Mutation; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000473:pathology; D013997:Time Factors
D008748:Methylcholanthrene; D015127:9,10-Dimethyl-1,2-benzanthracene
Chuvstvitel'nost' serykh i bezhevykh dzhungarskikh khomiachkov k blastomogennomu deĭstviiu 7,12-dimetilbenz(a)antratsena i 3-metilkholantrena.