Pseudohyperaldosteronism (Liddle's syndrome): a case report.
A 22-year-old man was hospitalized because of hypertension, hypokalemic alkalosis and suppressed plasma renin activity. Although these findings were similar to hyperaldosteronism, plasma aldosterone concentration and urinary aldosterone excretion were lower than the normal range. Adrenocortical function also was normal except for aldosterone. Treatment with spironolactone, salt restriction and potassium supplementation improved the hypokalemia but not the hypertension. Blood pressure decreased markedly after administration of triamterene.
D000305:Adrenal Cortex Hormones / Q000032:analysis; D000328:Adult; D000471:Alkalosis / Q000175:diagnosis / Q000378:metabolism; D006801:Humans; D006929:Hyperaldosteronism / Q000175:diagnosis* / Q000378:metabolism; D007008:Hypokalemia / Q000175:diagnosis / Q000378:metabolism; D008297:Male
D000305:Adrenal Cortex Hormones