Relationship between African admixture and blood pressure variation in the Caribbean.
The genetic contribution to blood pressure variance is examined by studying a selected group of genes. Of 368 individuals, 48.1% received one-half or more of their genes from an African ancestor and of this group 18.1 and 17.0% exhibit systolic and diastolic hypertension, respectively. A chi-square test was used to examine the dependence of blood pressure on percentage African ancestry. The chi-square values were not significant for systolic or diastolic pressures. It is likely that other factors are strongly related to African admixture and these factors are the true modifiers of blood pressure.
D000293:Adolescent; D000328:Adult; D000354:Africa, Western / Q000208:ethnology; D000367:Age Factors; D000368:Aged; D001789:Blood Group Antigens / Q000235:genetics; D001794:Blood Pressure; D001798:Blood Proteins / Q000235:genetics; D003710:Demography; D005260:Female; D005787:Gene Frequency; D014644:Genetic Variation; D006801:Humans; D006973:Hypertension / Q000235:genetics / Q000503:physiopathology; D007199:Indians, South American; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012737:Sex Factors; D013020:South America / Q000208:ethnology; D014900:West Indies
D001789:Blood Group Antigens; D001798:Blood Proteins