[Determination of Mycoplasma pneumoniae antigens and antibodies by the immunoenzyme method in patients with respiratory tract diseases].
The optimum conditions for carrying out the enzyme immunoassay (EIA) with a view to determine M. pneumoniae antigen and antibodies to them in the sera of patients with different respiratory diseases were established. The use of the specially modified EIA technique made it possible to reveal that patients with tuberculosis and chronic pneumonia showed similar occurrence of M. pneumoniae (35.7% and 35.0% of cases, respectively), while in patients with pulmonary sarcoidosis M. pneumoniae occurred in 27.2% of cases. At the same time the occurrence of antibodies in patients with chronic pneumonia and sarcoidosis was more than three times greater than in tuberculosis patients.
D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial / Q000032:analysis*; D002908:Chronic Disease; D006801:Humans; D007124:Immunoenzyme Techniques; D008171:Lung Diseases / Q000276:immunology; D009177:Mycoplasma pneumoniae / Q000276:immunology*; D011014:Pneumonia / Q000276:immunology; D012141:Respiratory Tract Infections / Q000276:immunology*; D012507:Sarcoidosis / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000276:immunology
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial
Opredelenie antigenov Mycoplasma pneumoniae i antitel k nim immunofermentnym metodom u bol'nykh s zabolevaniiami dykhatel'nykh puteĭ.