Comparison of radionuclear scintigraphy and liver biopsy in the evaluation of neonatal cholestasis.
Twenty-eight patients with neonatal cholestasis were given appropriate tests to arrive at a definitive diagnosis. Comparison of the results showing total obstruction on scintigraphy but not on liver biopsy is presented. It is suggested that liver biopsy be performed to confirm the diagnosis prior to undertaking exploratory laparotomy when radionuclear scan suggests extrahepatic biliary atresia.
D001652:Bile Ducts / Q000002:abnormalities; D005260:Female; D006801:Humans; D007098:Imino Acids; D007223:Infant; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008099:Liver / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D015609:Organotechnetium Compounds; D011300:Preoperative Care; D011877:Radionuclide Imaging; D013667:Technetium
D007098:Imino Acids; D015609:Organotechnetium Compounds; D013667:Technetium; C003693:technetium Tc 99m PIPIDA