title: Origin of immune diversity: genetic variation and selection.
mesh_terms: D000483:Alleles; D000818:Animals; D000915:Antibody Affinity; D000916:Antibody Diversity; D005075:Biological Evolution; D002872:Chromosome Deletion; D014644:Genetic Variation; D006801:Humans; D007127:Immunoglobulin Constant Regions / Q000235:genetics; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D007135:Immunoglobulin Variable Region / Q000235:genetics; D007136:Immunoglobulins / Q000235:genetics*; D046911:Macromolecular Substances; D008285:Major Histocompatibility Complex; D008954:Models, Biological; D009154:Mutation; D011948:Receptors, Antigen, T-Cell / Q000235:genetics*; D011995:Recombination, Genetic; D013950:Thymus Gland / Q000276:immunology
chemical_list: D007127:Immunoglobulin Constant Regions; D007143:Immunoglobulin Heavy Chains; D007135:Immunoglobulin Variable Region; D007136:Immunoglobulins; D046911:Macromolecular Substances; D011948:Receptors, Antigen, T-Cell