Primary cytogenetic abnormality detected in an endometrial adenocarcinoma.
Cytogenetic findings obtained from an endometrial adenocarcinoma stage 1A are reported. The primary stem line was pseudodiploid with an abnormal chromosome #8. Three side lines were noted, which collectively involved chromosomes X, #8, #12, and two members of group D. A small percentage of cells was either pseudotetraploid or near-tetraploid. Double minutes were noted in one of the latter cells. Interest in the case is centered on the finding of what appeared to be the primary chromosomal change.
D000230:Adenocarcinoma / Q000235:genetics*; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D008677:Metaphase; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000235:genetics*