Lymphocyte subpopulations before therapy in patients with uveal malignant melanoma.
T-cell and B-cell lymphocyte subpopulations, monocytes, granulocytes, and immunoglobulin receptors were measured with monoclonal antibodies and flow cytometric techniques in the peripheral blood of 266 patients with posterior uveal melanoma before therapy. Statistically significant differences were found in T-helper/inducer (OKT4), T-suppressor/cytotoxic (OKT8), and B-lymphocyte populations between patients with uveal melanoma and age-matched controls.
D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007958:Leukocyte Count; D008214:Lymphocytes / Q000145:classification; D008297:Male; D008545:Melanoma / Q000276:immunology / Q000473:pathology*; D008875:Middle Aged; D014604:Uveal Neoplasms / Q000276:immunology / Q000473:pathology*