Construction and experimental application of a catheter for selective arterial kidney perfusion in situ.
In order to improve dog kidney perfusion in situ with a protective solution, a perfusion catheter was constructed which allowed continuous pressure measurement in the center of the catheter tip during perfusion. Using this catheter, the equilibration of the extracellular space with a protective solution (HTK solution) was found to be pressure dependent. Continuous pressure and resistance control is therefore a prerequisite for reliable organ protection.
D000818:Animals; D001794:Blood Pressure; D002404:Catheterization / Q000295:instrumentation*; D004285:Dogs; D005260:Female; D005947:Glucose; D008297:Male; D008353:Mannitol; D010477:Perfusion / Q000295:instrumentation; D011189:Potassium Chloride; D011343:Procaine; D012077:Renal Artery
C039984:Bretschneider cardioplegic solution; D008353:Mannitol; D011343:Procaine; D011189:Potassium Chloride; D005947:Glucose