title: Indications and experimental preparatory studies for pancreas transplantation.
abstract: Clinical and experimental evidence support the metabolic aetiology of diabetic microangiopathy. This paves the way for its management by transplantation of endocrine pancreas. In an informative article, the authors attempts to conceptualize their position concerning indications for pancreas transplantation and offer a review of their own experimental studies, a prerequisite before actual clinical application.
mesh_terms: D000818:Animals; D003374:Coumarins / Q000494:pharmacology; D003925:Diabetic Angiopathies / Q000628:therapy; D003928:Diabetic Nephropathies / Q000628:therapy; D004285:Dogs; D004338:Drug Combinations / Q000494:pharmacology; D005452:Fluoresceins / Q000494:pharmacology; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D006896:Hydroxyethylrutoside / Q000031:analogs & derivatives / Q000494:pharmacology; D016381:Islets of Langerhans Transplantation; D009941:Organomercury Compounds / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D003374:Coumarins; D004338:Drug Combinations; D005452:Fluoresceins; D006896:Hydroxyethylrutoside; D009941:Organomercury Compounds; C013731:Venalot; C010604:mercurascan; D013752:Tetracycline