The metabolic activation of ronidazole [(1-methyl-5-nitroimidazole-2-yl)-methyl carbamate] to reactive metabolites by mammalian, cecal bacterial and T. foetus enzymes.
D000818:Animals; D001692:Biological Transport; D001711:Biotransformation; D002432:Cecum / Q000382:microbiology; D004755:Enterobacteriaceae / Q000201:enzymology / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008862:Microsomes, Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism*; D009593:Nitroimidazoles / Q000378:metabolism*; D011485:Protein Binding; D051381:Rats; D012385:Ronidazole / Q000378:metabolism*; D013552:Swine; D014208:Treponema / Q000201:enzymology / Q000378:metabolism*
D009593:Nitroimidazoles; D012385:Ronidazole