title: Salivary duct adenocarcinoma: a high grade malignancy.
abstract: Salivary duct carcinomas of the major salivary glands have two major distinguishing features. They closely resemble ductal carcinomas of the breast and they are high-grade malignancies. In general, but particularly for carcinomas measuring three or more centimeters in size, the clinical course is one characterized by a resistance to local control, metastases to regional lymph nodes and distant sites, and death within a few years after primary surgical treatment.
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary / Q000628:therapy / Q000648:ultrastructure*; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010307:Parotid Neoplasms / Q000628:therapy / Q000648:ultrastructure*; D011379:Prognosis; D012468:Salivary Gland Neoplasms / Q000648:ultrastructure*; D013365:Submandibular Gland Neoplasms / Q000628:therapy / Q000648:ultrastructure*