Gonadotropin secretion dynamics in patients with Klinefelter's syndrome in relation to age.
In 28 chromatin-positive patients distributed into age-decade lots, the circulating levels of gonadotropins as shown by radioimmunoassay (RIA), were higher than normal. FSH was especially high while LH had significant fluctuations between the lots. A hypothalamic determinism for these anomalies is suggested.
D000293:Adolescent; D000328:Adult; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007713:Klinefelter Syndrome / Q000097:blood / Q000503:physiopathology*; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone