Chlorpromazine-associated haemolysis in anorexia nervosa.
Chlorpromazine therapy in a patient with anorexia nervosa was associated with haemolytic anaemia. In vitro red cell findings included an increased degree of red cell autohaemolysis and a chlorpromazine-dependent Heinz body formation both corrected with exogenous glucose. Activities of red cell enzymes involved with the glycolytic pathway or glutathione metabolism were normal.
D000293:Adolescent; D000743:Anemia, Hemolytic / Q000097:blood / Q000139:chemically induced*; D000856:Anorexia Nervosa / Q000097:blood* / Q000150:complications; D002746:Chlorpromazine / Q000009:adverse effects*; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006366:Heinz Bodies / Q000187:drug effects; D006801:Humans
D002746:Chlorpromazine