title: Investigation of gonadotropin-thyrotropin overlapping and hormonal imprinting in the rat testis.
abstract: In the neonatal period both gonadotropin and thyrotropin increase the weight of the testis, influence considerably the diameter of the contorted tubules increase the occurrence of Sertoli cells and decrease the number of spermatogonia. These phenomena can still be observed at the age of seven days but they disappear by the age of six weeks; at that time the hormones decrease the weight of the testis. One single TSH treatment administered in the neonatal period considerably increased the weight of the testis and the diameter of the channels when investigated at the age of six weeks. Gonadotropin had none of these effects. The phenomenon of imprinting could be proved as in the animals pretreated with TSH, gonadotropin given at the age of six weeks decreased the weight of the testis and both hormones decreased the diameter of the seminiferous cords.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development; D002452:Cell Count; D005640:Follicle Stimulating Hormone / Q000502:physiology*; D007986:Luteinizing Hormone / Q000502:physiology*; D008297:Male; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D012671:Seminiferous Tubules / Q000254:growth & development; D012708:Sertoli Cells / Q000166:cytology; D013737:Testis / Q000254:growth & development*; D013972:Thyrotropin / Q000502:physiology*
chemical_list: D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin