title: [Synthesis of tyrosine and 3,4-dihydroxyphenylalanine by Citrobacter freundii bacteria from lactic acid].
abstract: A possibility of using lactic acid as a precursor for the synthesis of L-tyrosine and L-3,4-dihydroxyphenylalanine (DOPA) by Citrobacter freundii 62 and 63 was established. The synthesis of tyrosine from lactic acid occurs at a phenol concentration of less than 0.6%. The conditions were found which enable C. freundii 62 and 63 to synthesize from lactic acid tyrosine and DOPA with the yield of 35-38 g/l and 32-33 g/l, respectively.
mesh_terms: D000332:Aerobiosis; D002954:Citrobacter / Q000187:drug effects / Q000201:enzymology*; D003470:Culture Media / Q000378:metabolism; D004295:Dihydroxyphenylalanine / Q000096:biosynthesis*; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000378:metabolism*; D019344:Lactic Acid; D011773:Pyruvates / Q000378:metabolism; D019289:Pyruvic Acid; D013696:Temperature; D014443:Tyrosine / Q000096:biosynthesis*
chemical_list: D003470:Culture Media; D007773:Lactates; D011773:Pyruvates; D019344:Lactic Acid; D014443:Tyrosine; D004295:Dihydroxyphenylalanine; D019289:Pyruvic Acid
vernacular_title: Sintez tirozina i 3,4-dioksifenilalanina bakteriiami Citrobacter freundii iz molochnoĭ kisloty.