Neutrophil glutathione peroxidase activity in iron deficiency anaemia.
Neutrophil glutathione peroxidase (GSH-Px) activity was studied in 30 children with nutritional iron deficiency anaemia and 25 healthy age-matched controls. Initially GSH-Px in iron deficient anaemic children was significantly (p less than 0.001) low compared to the control group. All patients were subjected to iron therapy but only 8 returned for follow-up. The GSH-Px activity in all 8 cases rose to normal levels after therapy. These results suggest a relationship between iron and GSH-Px activity.
D000747:Anemia, Hypochromic / Q000188:drug therapy / Q000201:enzymology*; D002675:Child, Preschool; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D007223:Infant; D007501:Iron / Q000627:therapeutic use; D009504:Neutrophils / Q000201:enzymology*
D007501:Iron; D005979:Glutathione Peroxidase