title: [The effect of acupuncture on hematologic and biochemical values in dogs with endoparasitic infections].
abstract: Selected hematological and biochemical indicators in blood were studied in seven dogs for 57 days. Six dogs were exposed to long-term, pre-experimental, natural invasion of the endoparasite Trichuris vulpis, one dog to Toxascaris leonina. In both cases the invasion of parasites was only weak, without any clinical symptoms. Acupuncture was performed on the first to fourth experimental days by steel acupuncture needles used in human medicine by introducing them into Gv-14, ST-36 and SP-6 points for twenty minutes. The results were evaluated statistically and compared with the samples taken from individual animals prior to acupuncture application. The changes in blood serum protein fractions in six dogs suffering from trichuriasis were compared with the control group of animals invaded in a similar way and with physiological standard. The results confirmed a statistically highly significant difference in the values of blood sedimentation (increase at four samplings from the 9th to 38th experimental days). At two samplings performed on the 35th and 57th experimental days a statistically highly significant difference was observed in the dogs suffering from trichuriasis as compared with the control group: in the relative values of globulin beta-fraction (increase), globulin gamma-fraction (decrease) and albumin (decrease) of the blood serum. In these dogs the A/G quotient decreased statistically highly significantly. There were no substantial changes in the level of total protein during the experiment, however, there was a trend of eosinophilia. These findings suggest the activation of the immunity system, but the invasion of Trichuris vulpis was not markedly influenced. The above-mentioned changes in blood values were not observed in the dog invaded with Toxascaris leonina, the parasite invasion remained at the pre-experimental level. No marked changes of the long-term duration were observed in the values of the other hematological and biochemical tests in any of the experimental animals. The control group consisting of four dogs without endoparasitic invasion, clinically in good condition, was also subjected to acupuncture at Gv-14, ST-36, SP-6 points. In the course of this study, the originally lower values of hemoglobin, hematocrit, erythrocyte number, leucocyte number and number of the segmented neutrophilic granulocytes increased and reached the physiological standard. Towards the end of this experiment all values of hematological and biochemical blood examinations were similar like those of the experimental group.
mesh_terms: D000136:Acid-Base Equilibrium; D015670:Acupuncture Therapy / Q000662:veterinary*; D000818:Animals; D001196:Ascariasis / Q000662:veterinary*; D001772:Blood Cell Count / Q000662:veterinary; D001799:Blood Sedimentation; D004283:Dog Diseases / Q000097:blood*; D004285:Dogs; D005260:Female; D008297:Male; D014120:Toxocariasis / Q000097:blood / Q000662:veterinary*; D014257:Trichuriasis / Q000097:blood / Q000662:veterinary*
vernacular_title: Vliv akupunktury na hematologické a biochemické hodnoty psů s endoparazitární invazí.