Paradoxical pulmonary vasoconstriction induced by nitroglycerin in idiopathic pulmonary hypertension.
Administration of intravenous nitroglycerin in a patient with idiopathic pulmonary hypertension resulted in an increase in pulmonary artery pressure associated with a decrease in blood flow that is best explained by an increase in pulmonary vascular resistance. This observation highlights the need for hemodynamic monitoring when potent vasodilators are used in this disorder.
D000293:Adolescent; D006328:Cardiac Catheterization; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D005996:Nitroglycerin / Q000009:adverse effects*; D011652:Pulmonary Circulation / Q000187:drug effects*; D014655:Vascular Resistance / Q000187:drug effects*
D005996:Nitroglycerin