Myelofibrosis, autoimmune haemolytic anaemia and Tn-polyagglutinability.
A patient with myelofibrosis was studied for about four years. During this period he developed autoimmune haemolytic anaemia, a rare complication of myelofibrosis. Furthermore, about two years after the investigation started, his red blood cells, previously normal, became Tn-polyagglutinable, a change known to be due to somatic mutation in haemopoietic stem cells.
D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000209:etiology*; D004912:Erythrocytes / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D011946:Receptors, Antigen / Q000502:physiology*; D012204:Rh-Hr Blood-Group System
D011946:Receptors, Antigen; D012204:Rh-Hr Blood-Group System; C028641:Tn receptor