title: Protein transfer in hyperoxic induced pleural effusion in the rat.
abstract: In order to study the kinetics and pathways of protein transfer in pleural effusion, rats with pleurisy associated with hyperoxic pulmonary edema were injected either intrapleurally or intravenously with tracers. 125I-Albumin was used to obtain quantitative data. Anti horseradish peroxidase used as a morphological tracer, allowed a precise localization of the pathways used for the transfer. It has been possible to demonstrate that, in this model, the pleural effusion is produced by a plasma exudation accumulated in the lung interstitium, transferred through the visceral pleura and resorbed by the lymphatics of the parietal costal and diaphragmatic pleurae.
mesh_terms: D000418:Albumins / Q000378:metabolism; D000818:Animals; D004195:Disease Models, Animal; D006735:Horseradish Peroxidase / Q000276:immunology; D007074:Immunoglobulin G / Q000378:metabolism; D007700:Kinetics; D008297:Male; D010100:Oxygen / Q000633:toxicity*; D010996:Pleural Effusion / Q000209:etiology / Q000378:metabolism* / Q000473:pathology; D010998:Pleurisy / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D051381:Rats
chemical_list: D000418:Albumins; D007074:Immunoglobulin G; D011506:Proteins; D006735:Horseradish Peroxidase; D010100:Oxygen