[Structure of the centriole complex in mouse hepatocytes in the experimental induction of a G2 block].
In the regenerating liver hepatocytes the centriolar cycle is retarded corresponding to the delay of the nuclear cycle up to the beginning of G2-block. A prolonged staying of cells in the premitotic condition results in the phenomenon that according to their DNA these cells correspond to the G2-period, whereas according to their centriolar complex structure they move into the following G1 and G0-periods, passing mitosis. Thus, in the G2-blocked hepatocytes there is a separation of the nuclear cycle and centriolar cycles. Moreover, during the diping action the centriolar capacity of forming cytoplasmic and mitotic microtubules is suppressed.
D000818:Animals; D001388:Aziridines / Q000494:pharmacology; D002502:Centrioles / Q000187:drug effects / Q000648:ultrastructure*; D004261:DNA Replication / Q000187:drug effects; D006498:Hepatectomy; D007399:Interphase / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000648:ultrastructure*; D008115:Liver Regeneration / Q000187:drug effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008854:Microscopy, Electron; D008870:Microtubules / Q000187:drug effects / Q000648:ultrastructure; D013997:Time Factors
D001388:Aziridines; C007526:dipin
Stroenie tsentrioliarnogo kompleksa v gepatotsitakh myshi pri éksperimental'noĭ induktsii G2-bloka.