title: Lectin histochemistry of submandibular glands following duct-ligation in mice and rats.
abstract: Lectin binding patterns of Con A, PNA, SBA, DBA, WGA, RCA-1 and UEA-1 were carried out in duct-ligated submandibular glands (SMGs) of rats that displayed acute degenerating changes. Lectin staining was also related to histologic changes. Proliferating epithelial cells which were probably derived from intercalated duct cells showed a strong SBA and WGA staining on the 3rd day. Duct-like and cystic structures appeared on the 7th day and staining by PNA, SBA, WGA, RCA-1 and Con A was described. In mice, lectin binding after duct ligation appeared similar to the rat. In the long-term observation of mice SMGs, acinar cell regeneration occurred between the 21st and 42nd days and they stained strongly for DBA.
mesh_terms: D000818:Animals; D050260:Carbohydrate Metabolism; D005260:Female; D006651:Histocytochemistry; D037102:Lectins / Q000378:metabolism*; D008026:Ligation; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D051381:Rats; D011919:Rats, Inbred Strains; D012466:Salivary Gland Diseases / Q000378:metabolism*; D013363:Submandibular Gland / Q000032:analysis / Q000378:metabolism* / Q000601:surgery; D013364:Submandibular Gland Diseases / Q000378:metabolism* / Q000473:pathology; D013997:Time Factors
chemical_list: D037102:Lectins