Effects of naloxone upon the behavioural organisation of specific defeat activities in intruder mice: assessment by cluster analysis.
The present experiment examined the effects of naloxone (0.5, 2.5 and 12.5 mg/kg) upon the responses of male Swiss mice to attack by aggressive male conspecifics in the resident-intruder paradigm by measuring the time spent in broad behavioural categories, frequency of individual acts or postures, and performing a cluster analysis of activities according to their frequency and position within the behavioural sequence. The former two measures detected little naloxone-induced change in behaviour. Cluster analysis revealed changes in behavioural organisation which suggested modification in the motivation and/or function underlying specific defeat behaviour.
D000374:Aggression / Q000187:drug effects*; D000704:Analysis of Variance; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004924:Escape Reaction / Q000187:drug effects*; D008297:Male; D051379:Mice; D009042:Motivation; D009270:Naloxone / Q000494:pharmacology*
D009270:Naloxone