title: Synapsis and synaptic adjustment in an infertile human male heterozygous for a pericentric inversion in chromosome 1.
abstract: Synapsis and "synaptic adjustment" were analyzed, using electron microscopy in silver stained surface microspreads of inversion-bearing spermatocytes, in an infertile human male with an inherited pericentric inversion in chromosome 1. Possible reasons for his infertility are discussed.
mesh_terms: D000328:Adult; D007446:Chromosome Inversion; D002900:Chromosomes, Human, 1-3; D006579:Heterozygote; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D008297:Male; D008540:Meiosis; D008854:Microscopy, Electron; D013090:Spermatocytes / Q000473:pathology / Q000648:ultrastructure*; D013573:Synaptonemal Complex