title: Postnatal developmental profiles of filamentous actin and of 200 kDa neurofilament polypeptide in the visual cortex of light- and dark-reared rats and their relationship to critical period plasticity.
abstract: The concept of critical period plasticity in rat visual cortex has been studied in terms of changes in the level of filamentous actin and of the 200 kDa neurofilament polypeptide. Our results suggest that the postnatal developmental profile of filamentous actin is affected by visual experience, as a consequence of eye-opening. No such correlation, however, is detected for the 200 kDa neurofilament polypeptide. The significance of these findings in relationship to neuronal plasticity is discussed in terms of changes in the state and equilibrium conditions of the cytoskeletal proteins.
mesh_terms: D000199:Actins / Q000378:metabolism*; D000818:Animals; D003624:Darkness; D007381:Intermediate Filament Proteins / Q000378:metabolism*; D008027:Light; D016900:Neurofilament Proteins; D051381:Rats; D014793:Visual Cortex / Q000254:growth & development* / Q000378:metabolism / Q000528:radiation effects
chemical_list: D000199:Actins; D007381:Intermediate Filament Proteins; D016900:Neurofilament Proteins