Review of the application of response surface methodology in the combination therapy of cancer.
D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage* / Q000627:therapeutic use / Q000633:toxicity; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D004347:Drug Interactions; D004357:Drug Synergism; D008962:Models, Theoretical; D009374:Neoplasms, Experimental / Q000188:drug therapy; D012107:Research Design; D013223:Statistics as Topic