title: Cytogenetics of human sperm: meiotic segregation in two translocation carriers.
abstract: Meiotic segregation products were studied in sperm from two men heterozygous for the reciprocal translocations t(8;15)(p22;q21) and t(3;16)(p23;q24). A total of 226 and 201 sperm complements, respectively, were analyzed. In each translocation, 63% of complements were unbalanced, and alternate and adjacent 1 percentages were similar. The 3:1 segregation frequencies produced by the two translocations were 3.5% and 5.0%.
mesh_terms: D000328:Adult; D002871:Chromosome Banding; D006579:Heterozygote; D006801:Humans; D007621:Karyotyping; D008297:Male; D008540:Meiosis; D013094:Spermatozoa / Q000166:cytology / Q000648:ultrastructure*; D014178:Translocation, Genetic