[Effect of guanethidine sympathectomy on cardiac functions in rat pups].
Catecholamine level in the blood, heart and adrenal tissues, and heart sensitivity to catecholamines were determined in 3-week-old rats after chemical sympathectomy. It was shown that tachycardia in sympathectomy rats was caused by increased heart sensitivity to catecholamines due to the reduction in their concentration.
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D004837:Epinephrine / Q000378:metabolism / Q000494:pharmacology; D006145:Guanethidine; D006321:Heart / Q000187:drug effects / Q000254:growth & development / Q000294:innervation*; D006339:Heart Rate / Q000187:drug effects; D009206:Myocardium / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D013563:Sympathectomy, Chemical; D013610:Tachycardia / Q000139:chemically induced
D009638:Norepinephrine; D004837:Epinephrine; D006145:Guanethidine
Vliianie desimpatizatsii guanetidinom na funktsii serdtsa krysiat.