title: Nutritional nystagmus in infants.
abstract: Two infants presented with acquired infantile nystagmus. On examination, they manifested peculiar facies, growth and developmental delay, failure to thrive, and a Wernicke's type of nystagmus. Suspicion of a B vitamin deficiency resulted in correct diagnosis of dietary deficiency and/or enzymatic defect. In both instances, dietary treatment with B vitamins resulted in resolution of the nystagmus and improved growth and development of both individuals. Physicians, especially pediatricians and ophthalmologists, should be alert to the possibility of a Wernicke's type nystagmus in such infants, since the diagnosis may be critical to accurate diagnosis and treatment.
mesh_terms: D001710:Biotin / Q000172:deficiency / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D009748:Nutrition Disorders / Q000150:complications*; D009759:Nystagmus, Pathologic / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D015325:Pyruvate Dehydrogenase Complex Deficiency Disease; D013831:Thiamine / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D001710:Biotin; D013831:Thiamine