Fermentation production of L-homoserine by Corynebacterium sp. and its possible use in the preparation of threonine and lysine.
A mutant Corynebacterium sp. requiring threonine and cultivated for 3 d in a medium containing 15% sucrose, 8% corn-steep and 50 micrograms biotin per litre accumulated 14.5 g L-homoserine per litre. The possibility of fermenting the homoserine obtained for threonine and lysine production was investigated.
D003352:Corynebacterium / Q000235:genetics / Q000378:metabolism*; D003470:Culture Media; D005285:Fermentation; D006714:Homoserine / Q000096:biosynthesis* / Q000378:metabolism; D007700:Kinetics; D008239:Lysine / Q000096:biosynthesis*; D009154:Mutation; D013045:Species Specificity; D013912:Threonine / Q000096:biosynthesis*
D003470:Culture Media; D013912:Threonine; D006714:Homoserine; D008239:Lysine