Bone marrow lambda-type light chain crystalline structures associated with multiple myeloma.
A 58-year-old man showed bone marrow crystalline structures associated with a lambda light chain producing multiple myeloma. Analysis and processing of electron images clearly displayed the periodic structure of the crystals. Immunochemistry suggested that they contained the whole or a fragmented constant portion of immunoglobulin.
D001853:Bone Marrow / Q000032:analysis / Q000473:pathology* / Q000648:ultrastructure; D003460:Crystallization; D006801:Humans; D007124:Immunoenzyme Techniques; D007147:Immunoglobulin Light Chains / Q000032:analysis*; D007146:Immunoglobulin lambda-Chains / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000276:immunology*; D010950:Plasma Cells / Q000276:immunology
D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains