Surface membrane O-alkyl lipid concentration and metastasizing behavior in transplantable rat mammary carcinomas.
Whole cell and surface membrane O-alkyl and alk-1-enyl lipid concentrations of 11 transplantable rat mammary carcinomas were measured. A correlation was found between surface membrane O-alkyl lipid levels and metastasizing behavior. No relationship was found between alk-1-enyl lipid concentrations and metastasizing behavior. A possible correlation was found between the product of growth rate and rank order of metastasizing behavior versus surface membrane O-alkyl lipid concentration. Growth rate alone did not correlate with surface membrane O-alkyl lipid concentration.
D000475:Alkenes; D000818:Animals; D002458:Cell Fractionation; D002462:Cell Membrane / Q000378:metabolism; D004987:Ethers; D008325:Mammary Neoplasms, Experimental / Q000378:metabolism* / Q000473:pathology; D008563:Membrane Lipids / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats
D000475:Alkenes; D004987:Ethers; D008563:Membrane Lipids; D010743:Phospholipids