Acute valproic acid toxicity at therapeutic concentrations.
A previously healthy nonepileptic 11-year-old girl presented with confusion and disorientation after an acute ingestion of valproic acid. Her serum concentration of valproic acid was 39.6 mcg/ml, a range normally considered "therapeutic" in the control of seizures. She recovered without sequelae despite the subsequent attainment of higher valproic acid concentrations.
D002648:Child; D003072:Cognition Disorders / Q000139:chemically induced*; D003221:Confusion / Q000139:chemically induced*; D005260:Female; D006801:Humans; D019966:Substance-Related Disorders; D014635:Valproic Acid / Q000097:blood / Q000506:poisoning*
D014635:Valproic Acid