[The coincidence of gonadal dysgenesis and hyperprolactinemia].
It was reported about 6 female patients aged from 3 to 31 years (average age 18 years) with gonadal dysgenesis and hyperprolactinemia. Beside one all these females were not treated with synthetic sexual steroids. In 5 of the 6 patients both hyperprolactinemic and hypergonadotropic serum levels were observed. In one case the gonadotropic serum levels were normal. In 4 patients a stimulation test with GRH-TRH or Arg-GRH-TRH, respectively, was performed. In patients with gonadal dysgenesis a change on the area of the hypothalamic-hypophyseal axis is supposed to cause the hyperprolactinemia.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006059:Gonadal Dysgenesis / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D010906:Pituitary Hormone-Releasing Hormones; D011388:Prolactin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone; D014424:Turner Syndrome / Q000097:blood*
D010906:Pituitary Hormone-Releasing Hormones; D004958:Estradiol; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Koinzidenz von Gonadendysgenesie und Hyperprolaktinämie.