Immunologic status of children after splenectomy.
Fifty-six splenectomized children were reexamined to verify their immune status and were compared with a control group. Except for Werlhof's disease, there was a significantly increased serum IgG level in splenectomized children, as compared with the control group, and diminished IgA and IgM levels. Susceptibility to postoperative infections is dependent on age and underlying disease. Generally, susceptibility cannot be predicted following splenectomy in the individual case.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007109:Immunity; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007223:Infant; D007231:Infant, Newborn; D013156:Splenectomy
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M