title: Jackfruit (Artocarpus integrifolia) and the Agaricus mushroom lectin fit also to the so-called peanut receptor.
abstract: The lectin from jackfruit (Artocarpus integrifolia) reacts with the peanut-specific lectin receptor represented by the T-disaccharide, which is also part of the Thomsen (= T)-Friedenreich antigen, namely O-beta-D-galactosyl-(1----3)-N-acetyl-D-galactosamine. The difference between the jackfruit lectin and peanut lectin has been shown to be mainly due to the further linkage of the T-disaccharide: Whereas the peanut lectin reacts with both anomeric forms, jackfruit lectin and the closely - with respect to its specificity - related Agaricus bisporus mushroom lectin react predominantly with the alpha-linked T-disaccharide, so that they cannot detect the lipid-linked T-disaccharide, as the peanut lectin does.
mesh_terms: D015295:Antigens, Tumor-Associated, Carbohydrate; D001665:Binding Sites; D003429:Cross Reactions; D004187:Disaccharides / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006801:Humans; D005779:Immunodiffusion; D037102:Lectins / Q000378:metabolism*; D008213:Lymphocyte Activation; D037121:Plant Lectins; D011975:Receptors, Mitogen / Q000378:metabolism*
chemical_list: C041433:Agaricus lectins; D015295:Antigens, Tumor-Associated, Carbohydrate; D004187:Disaccharides; D006023:Glycoproteins; D037102:Lectins; D037121:Plant Lectins; D011975:Receptors, Mitogen; C043696:jacalin; C038223:peanut agglutinin receptor; C016467:Thomsen-Friedenreich antigen