Carrier-mediated transport of amino acids through the blood-retinal and the blood-brain barriers.
The uptake-index method was used to study the transport of amino acids through the blood-retinal and blood-brain barriers in rats. The results indicate the existence of at least two different, similar carriers in both barriers, i.e., one each for neutral and basic amino acids. A third separate transport system for taurine was found in the blood-retinal barrier. All of the carrier systems studied transported amino acids from blood to nervous tissue.
D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001692:Biological Transport; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism; D002352:Carrier Proteins / Q000502:physiology*; D008297:Male; D010857:Pigment Epithelium of Eye / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012171:Retinal Vessels / Q000378:metabolism*
D000596:Amino Acids; D002352:Carrier Proteins