Amoebic meningo-encephalitis due to a free-living amoeba. A case report.
A 47-year-old man developed an undiagnosed encephalitic illness and died within 12 days. Autopsy showed focal granulomatous lesions associated with a necrotizing vasculitis. Light microscopy revealed the presence of free-living amoebae morphologically resembling Acanthamoeba species. The pathology of this form of meningo-encephalitis is contrasted with that caused by Naegleria fowleri infection, and attention is drawn to its existence within the RSA.
D000562:Amebiasis / Q000473:pathology; D001921:Brain / Q000473:pathology*; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged