title: Modulation of red cell metabolism by states of decreased activation: comparison between states.
abstract: Marked decline of red cell metabolism has been described during the acute state of decreased activation associated with the stylized mental technique of transcendental meditation (TM) in long-term meditators (5-10 years regular elicitation, TM instructors). It is not known whether unstylized rest is accompanied by a similar effect and it is not known what effector(s) may contribute to red cell metabolic changes in these states. In the present study ordinary, unstylized rest was found to be accompanied by small increase of red cell glycolytic rate. Apparently, either repeated elicitation of TM behavior or some special feature of this practice become associated with new mechanisms of metabolic control than those previously in operation. Although the data of this study do not permit isolation of the precise psychological determinants of this effect, the range of possible physiological effectors can be delimited. Blood pH, PCO2, PO2, and phosphate can be eliminated as significant for red cell metabolic control during both TM and rest, and based upon related studies, several known hormones such as insulin, T3, T4, arginine vasopressin, oxytocin, prolactin and growth hormone can also be eliminated as responsible effector(s).
mesh_terms: D000136:Acid-Base Equilibrium; D000328:Adult; D002245:Carbon Dioxide / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006019:Glycolysis; D006728:Hormones / Q000097:blood; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D010100:Oxygen / Q000097:blood; D012064:Relaxation Therapy; D012146:Rest
chemical_list: D006728:Hormones; D007773:Lactates; D002245:Carbon Dioxide; D019344:Lactic Acid; D010100:Oxygen