title: Migraine--treatment of acute attack.
abstract: The treatment of an acute attack of classical or common migraine is sleep, an antinauseant such as metoclopramide, an analgesic, either aspirin or paracetamol, and in some patients 1 or 2 mg of ergotamine tartrate. Treatment should be given as early in the attack as possible and all drugs should, if possible, be given in a soluble or effervescent form. When vomiting occurs early in the attack, treatment is best given by suppository, inhalation or intramuscular injection. Ergotamine tartrate is only necessary in about one third of attacks and when used is best given by suppository or inhalation. Doses of ergotamine tartrate higher than 2 mg per attack or 6 mgs per week may cause toxic symptoms as may the abuse of analgesics.
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use; D000208:Acute Disease; D001241:Aspirin / Q000627:therapeutic use; D002110:Caffeine / Q000008:administration & dosage; D004878:Ergotamine; D004879:Ergotamines / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use; D008881:Migraine Disorders / Q000188:drug therapy* / Q000628:therapy; D012890:Sleep; D013997:Time Factors
chemical_list: D004879:Ergotamines; D000082:Acetaminophen; D002110:Caffeine; D008787:Metoclopramide; D004878:Ergotamine; D001241:Aspirin