Status marmoratus in fetal cortical transplants.
Adult rats received unilateral transplants of either embryonic day-17 fetal neocortex or striatum. Sixty-two percent of the fetal neocortical transplants grafted into the striatum, and 25% of these neocortical transplants placed in host neocortex had regions of hypermyelination, whereas none of the striatal transplants showed such an effect. There are similarities between these neuropathologic findings and status marmoratus in humans and animals with perinatal hypoxic injuries.
D000818:Animals; D001720:Birth Injuries / Q000150:complications; D002540:Cerebral Cortex / Q000473:pathology / Q000637:transplantation*; D003342:Corpus Striatum / Q000473:pathology / Q000637:transplantation; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009186:Myelin Sheath / Q000473:pathology*; D009422:Nervous System Diseases / Q000209:etiology / Q000473:pathology*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains