A new antitumor antibiotic, chromoxymycin. II. Production, isolation, characterization and antitumor activity.
Chromoxymycin is a new antitumor antibiotic produced by a new actinomycete named Streptomyces libani subsp. rubropurpureus No. 6362. Chromoxymycin is active against P388 leukemia and B16 melanoma in mice, and has weak antibacterial activity against some Gram-positive bacteria.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification* / Q000627:therapeutic use; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D008545:Melanoma / Q000188:drug therapy; D051379:Mice; D008826:Microbial Sensitivity Tests; D009930:Organic Chemicals; D013302:Streptomyces / Q000032:analysis
D000903:Antibiotics, Antineoplastic; D009930:Organic Chemicals; C048097:chromooxymycin