Pure seminoma of the testis: the results of radiation therapy in patients with elevated human chorionic gonadotropin titers.
The management and prognosis of human chorionic gonadotropin-producing seminoma still are controversial issues. In a review of 210 patients irradiated between 1950 and 1982, 10 had elevated human chorionic gonadotropin values: 3 with stage I, 6 with stage II and 1 with stage IV disease. All human chorionic gonadotropin values became negative: 4 postoperatively and 6 following radiotherapy. All patients are well with a mean followup of 6 years. One patient who suffered liver metastases only was salvaged by chemotherapy. Based on these patients human chorionic gonadotropin production is not an unfavorable prognostic sign in cases of pure seminoma.
D000328:Adult; D006063:Chorionic Gonadotropin / Q000378:metabolism*; D004407:Dysgerminoma / Q000378:metabolism / Q000401:mortality / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011882:Radiotherapy, High-Energy; D013736:Testicular Neoplasms / Q000378:metabolism / Q000401:mortality / Q000532:radiotherapy*
D006063:Chorionic Gonadotropin