[A long survival case of carcinoma of the colon with hepatic metastasis following intra-arterial infusion chemotherapy].
A 61-year-old man with double colon cancers and a solitary hepatic metastasis underwent right hemicolectomy and catheterization of the proper hepatic artery in April 1979. Intraarterial infusion chemotherapy of 5-FU, to a total of 8,000 mg, and Mitomycin C, to a total of 40 mg, was performed for thirty-two days. During chemotherapy, calcification appeared and occupied the metastatic lesion. The patient is presently in good health and has been disease-free for five years and nine months. In this case, it was supposed that obstruction of the peripheral tumor vessels was the most important causative factor of tumor calcification. This case was clinically valuable because tumor calcification proved to be a marker of tendency toward cure and complete cure of cancer.
D000230:Adenocarcinoma / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002114:Calcinosis / Q000473:pathology; D003110:Colonic Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage
D008937:Mitomycins; D016685:Mitomycin; D005472:Fluorouracil