title: [Fibrinolytic therapy of massive pulmonary embolism on the 1st postoperative day following cholecystectomy].
abstract: Two patients, aged 64 and 47 years, had a massive pulmonary embolism one day after cholecystectomy. Ultra-short fibrinolysis was undertaken with 1.5 million units of streptokinase. Both patients rapidly improved, with a fall in heart rate, pulmonary artery or central-venous pressure, and a rise in arterial pO2. There were no significant bleedings. Ultra-short fibrinolysis (maximally over one hour) can thus successfully lyse emboli--consisting of fresh plasminogen-rich coagulation thrombi in the early postoperative period--without re-opening wound- and capillary beds during this short period.
mesh_terms: D002763:Cholecystectomy; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000188:drug therapy*; D013300:Streptokinase / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase
vernacular_title: Fibrinolysetherapie bei massiver Lungenemobolie am ersten postoperativen Tag nach Cholezystektomie.