Dental caries vaccine: some problems solved?
The interest in a dental caries vaccine has been great over the past few years. Studies have shown two possible problems using Streptococcus mutans as an immunogen: (i) the production of heart reactive antibody, and (ii) the need to protect against several serotypes. Possible solutions to these problems are discussed.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial / Q000276:immunology; D001428:Bacterial Vaccines; D003429:Cross Reactions; D003731:Dental Caries / Q000517:prevention & control*; D006801:Humans; D009206:Myocardium / Q000276:immunology*; D012703:Serotyping; D013295:Streptococcus mutans / Q000145:classification / Q000276:immunology*
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines