title: Evaluation of a non-invasive method for the measurement of metabolic rate in humans.
abstract: Measurements of oxygen consumption (VO2) and carbon dioxide production (VCO2) can be used to calculate energy expenditure. Such data are useful in the nutritional management of a variety of pathological conditions. This study is an evaluation in vitro and in vivo of the mating of a canopy and a Beckman metabolic measurement cart 1 (MMC). The canopy allows for the collection of expired gases without facial attachments. Studies in vitro demonstrated the necessity of calibrating the CO2 analyser at the concentrations used in such a system (0.50-0.80% CO2). Measurements of VO2 were within + 12% to -8% of predicted values, and when calibrated at 0.50% and 0.75% CO2, measurements of VCO2 were within + 2% and -7% of predicted values. The studies in vivo revealed that VO2 and VCO2 were within +/- 11% of the values obtained by using a canopy-spirometer-computer system. The MMC plus canopy may provide an alternative method for the clinical measurement of VO2 and VCO2, especially in subjects unable to tolerate a tight-fitting mask for prolonged periods.
mesh_terms: D000328:Adult; D001481:Basal Metabolism; D002151:Calorimetry / Q000379:methods*; D002153:Calorimetry, Indirect / Q000295:instrumentation / Q000379:methods*; D002245:Carbon Dioxide / Q000032:analysis; D004734:Energy Metabolism; D006801:Humans; D066298:In Vitro Techniques; D010100:Oxygen / Q000032:analysis; D010101:Oxygen Consumption; D012119:Respiration
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen