Successful treatment of post-mitral valve annuloplasty Aspergillus flavus endocarditis.
Aspergillus endocarditis is associated with a very high mortality. Of approximately 67 cases reported in the English language literature, there have been only two known survivors. This report describes a patient with Aspergillus flavus endocarditis after mitral valve annuloplasty who recovered with combined surgical and antifungal therapy. This is the first successfully treated case due to A. flavus and the first involving an annuloplasty ring.
D000666:Amphotericin B / Q000627:therapeutic use*; D001228:Aspergillosis / Q000209:etiology / Q000628:therapy*; D001231:Aspergillus flavus; D003131:Combined Modality Therapy; D003596:Cytosine / Q000031:analogs & derivatives*; D004696:Endocarditis / Q000209:etiology / Q000628:therapy*; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use*; D006350:Heart Valve Prosthesis; D006801:Humans; D008875:Middle Aged; D008943:Mitral Valve; D008945:Mitral Valve Prolapse / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy*
D000666:Amphotericin B; D003596:Cytosine; D005437:Flucytosine