title: [Production of secalonic acid D by strains of Penicillium oxalicum and its toxic effects on chick embryos].
abstract: Over the years 1983 to 1984, eight strains of Penicillium oxalicum were isolated from feed mixtures for chickens; all of them produced on wheat secalonic acid D (1 to 22 mg X kg-1). As found out, toxic dose of secalonic acid D for two-day, three--day and four-day chicken embryos is 0.90, 2.80 and 3.80 micrograms, respectively. Teratogenic effects, microophthalmia and bilateral beak fissure was observed in the embryotoxicity range on all days of application.
mesh_terms: D000821:Animal Feed; D000818:Animals; D002642:Chick Embryo; D002645:Chickens; D010407:Penicillium / Q000378:metabolism*; D014966:Xanthenes / Q000096:biosynthesis / Q000633:toxicity*; D044004:Xanthones
chemical_list: D014966:Xanthenes; D044004:Xanthones; C009218:secalonic acid
vernacular_title: Produkce sekalonové kyseliny D kmeny Penicillium oxalicum a její toxické úcinky na kurecí zárodek.