In vitro susceptibility of Pseudomonas species to carbenicillin and trimethoprim-sulfamethoxazole.
We compared susceptibility tests of 47 Pseudomonas aeruginosa isolates and 40 Pseudomonas species to carbenicillin and trimethoprim-sulfamethoxazole by the MS-2 and Sceptor systems and agar dilution. The major and very major errors encountered in these tests in the MS-2 and Sceptor systems raise doubts about the accuracy of these methods for testing P. aeruginosa and confirm that they should not be used for testing the susceptibility of Pseudomonas species to the two drugs tested.
D002228:Carbenicillin / Q000494:pharmacology*; D003470:Culture Media; D004338:Drug Combinations / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D011933:Reagent Kits, Diagnostic; D013420:Sulfamethoxazole / Q000494:pharmacology*; D014295:Trimethoprim / Q000494:pharmacology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
D003470:Culture Media; D004338:Drug Combinations; D011933:Reagent Kits, Diagnostic; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D014295:Trimethoprim; D002228:Carbenicillin; D013420:Sulfamethoxazole