Adult lead poisoning.
Although the incidence of occupational and adult lead poisoning has declined, the problem still exists. It often goes unrecognized for long periods because of a low index of suspicion compounded by incomplete surveillance of risk populations. Abdominal pain, fatigue and arthralgia are the most frequent symptoms. Anemia, basophilic stippling of red blood cells and hyperuricemia are the most common clues. Diagnosis is based on blood lead levels. Chelation by calcium disodium edetate, followed by oral penicillamine, is the standard treatment.
D000328:Adult; D000368:Aged; D002118:Calcium / Q000627:therapeutic use; D004492:Edetic Acid / Q000627:therapeutic use; D006801:Humans; D007854:Lead / Q000097:blood; D007855:Lead Poisoning / Q000097:blood* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood* / Q000139:chemically induced; D011524:Protoporphyrins / Q000097:blood
D011524:Protoporphyrins; D007854:Lead; D004492:Edetic Acid; D002118:Calcium