[Dynamics of changes in the rat thymus gland as affected by intratracheal administration of 238Pu].
A study was made of the effect of intratracheal administration of 238Pu nitrate on rat thymus. Incorporation of an acutely effective dose of the radionuclide (740 kBq X kg-1) induced damages to all thymus structures. The optimal blastomogenic 238Pu amount (92.5 kBq X kg-1) administered during the chronic period of the disease caused complex changes of atrophic, hyper- and neoplastic nature the lymphoid component of the thymus being primarily damaged.
D000818:Animals; D005260:Female; D009381:Neoplasms, Radiation-Induced / Q000209:etiology; D011005:Plutonium / Q000008:administration & dosage; D051381:Rats; D013950:Thymus Gland / Q000528:radiation effects*; D013952:Thymus Hyperplasia / Q000209:etiology; D013953:Thymus Neoplasms / Q000209:etiology; D014132:Trachea
D011005:Plutonium
Dinamika izmeneniĭ vilochkovoĭ zhelezy krys pri intratrakheal'nom vvedenii 238Pu.