title: Inducement of therapeutic amenorrhea in mentally retarded women: two-year follow-up study.
abstract: Therapeutic amenorrhea was induced in 44 moderately to severely mentally retarded women, aged 15 to 44 years. Subjects received lynestrenol or norethisterone in an identical oral dose of 5 mg daily. After 24 months, total amenorrhea was found in 70% of the women in the lynestrenol group and in 76% of those in the norethisterone group.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000568:Amenorrhea / Q000139:chemically induced*; D001835:Body Weight; D004827:Epilepsy / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008607:Intellectual Disability; D008234:Lynestrenol / Q000627:therapeutic use*; D008598:Menstruation / Q000187:drug effects; D009640:Norethindrone / Q000627:therapeutic use*
chemical_list: D008234:Lynestrenol; D009640:Norethindrone