[Effect of antenatal ethanol exposures on the function of the hemato-encephalic barrier in animals].
Blood-brain barrier permeability for P32, H3-valine, H3-tyrosine, S35-methionine was investigated in rat offsprings, 20 and 60 days old, that had been antenatally exposed to ethanol. In experimental 20-day-old rat offsprings P32 incorporation in brain structures was lower than in the controls. In mature rats that had been exposed to antenatal ethanol, a different degree decrease in labelled amino acid penetration and alterations in P32 penetration into different brain structures were found. Significant differences in stress-induced changes of blood-brain barrier permeability were observed in experimental and control animals.
D000818:Animals; D001812:Blood-Brain Barrier / Q000187:drug effects*; D002463:Cell Membrane Permeability / Q000187:drug effects; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D009622:Noise / Q000009:adverse effects; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011868:Radioisotopes; D051381:Rats; D012588:Scintillation Counting; D013312:Stress, Physiological / Q000503:physiopathology; D014732:Vibration / Q000009:adverse effects
D011868:Radioisotopes; D000431:Ethanol
Vliianie antenatal'nykh vozdeĭstviĭ étanola na funktsiiu gematoéntsefalicheskogo bar'era u zhivotnykh.