The reduction of aromatic nitro compounds with Zn/Cu. A new synthesis of N-acetoxy-N-acetyl-arylamines.
A new and simple synthesis is described for N-acetoxy-N-acetyl-derivatives of trans-4-aminostilbene, 2-aminofluorene and 2-aminophenanthrene using a Zn/Cu-couple for the reduction of the nitro-aromatics. This method produces good yields and should also be applicable for other N-aryl-compounds. It can also be used for the reduction of nitro-aromatics to the respective arylamines and arylamides.
D003300:Copper; D005449:Fluorenes / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D010084:Oxidation-Reduction; D010616:Phenanthrenes / Q000138:chemical synthesis*; D013267:Stilbenes / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship; D015032:Zinc
D005449:Fluorenes; D007202:Indicators and Reagents; D010616:Phenanthrenes; D013267:Stilbenes; D003300:Copper; D015032:Zinc