title: Caldesmon association with smooth muscle thin filaments isolated in the presence and absence of calcium.
abstract: Thin filaments isolated from chicken gizzard smooth muscle in either the presence or the absence of Ca2+ possess identical caldesmon contents. Hence, a 'flip-flop' mechanism, involving Ca2+-dependent association and dissociation of caldesmon and thin filaments, does not appear to operate in vivo and is an unlikely model for caldesmon function.
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism*; D000818:Animals; D002118:Calcium / Q000502:physiology*; D002148:Calmodulin-Binding Proteins / Q000378:metabolism*; D002645:Chickens; D003599:Cytoskeleton / Q000378:metabolism*; D005895:Gizzard, Avian; D009130:Muscle, Smooth / Q000648:ultrastructure*; D011485:Protein Binding
chemical_list: D002148:Calmodulin-Binding Proteins; D002118:Calcium