title: Erythrocyte surface sialic acid in Ndama and Zebu cattle.
abstract: Erythrocyte surface sialic acid concentrations were measured in the trypano-tolerant Ndama and trypano-susceptible Zebu breeds of cattle. All animals were uninfected and had no records of previous exposure to infection by African pathogenic trypanosomes. Ndama adults had significantly (P less than 0.001) higher erythrocyte surface sialic acid concentrations than Ndama calves. Ndama adults and calves had significantly (P less than 0.001) higher erythrocyte surface sialic acid concentrations than Zebu adults. There were no significant differences between the packed cell volume (PCV), haemoglobin (Hb) concentrations and total leukocyte counts (WBC) of these breeds. The finding of much higher erythrocyte surface sialic acid concentrations (about 7-fold) in the Ndama than in the Zebu is discussed in relation to the induction of anaemia by trypanosome sialidase in both breeds and to how a relative trypano-tolerance may occur in the Ndama.
mesh_terms: D000818:Animals; D002417:Cattle / Q000097:blood* / Q000469:parasitology; D004910:Erythrocyte Membrane / Q000032:analysis*; D005260:Female; D008297:Male; D012794:Sialic Acids / Q000097:blood*; D014354:Trypanosomiasis, Bovine / Q000097:blood
chemical_list: D012794:Sialic Acids