[Complex immunochemical study of plasma proteins and soluble antigens of leukocytes in patients with ischemic heart disease during hemoperfusion therapy].
An immunochemical analysis of 16 individual plasma proteins and 8 leukocyte soluble antigens (LSA) was performed over time in 11 coronary patients after hemosorption. The concentration of plasma lipoproteins gradually returned to normal within 2-3 weeks. Leukocyte dysfunction in the patients manifested itself in change of the specific LSA concentration in hemolysates as compared to that in donors. Shortly after hemosorption a selective 2-8-fold increase in the LSA concentration in the hemolysates was noted. Response of the leukocyte system was observed in all the cases and recorded in repetition of the procedures. Individual LSA function is under study.
D000328:Adult; D000368:Aged; D000941:Antigens / Q000032:analysis*; D001324:Autoantigens / Q000032:analysis*; D001798:Blood Proteins / Q000032:analysis*; D003327:Coronary Disease / Q000097:blood / Q000628:therapy*; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D005779:Immunodiffusion; D007962:Leukocytes / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012995:Solubility
D000941:Antigens; D001324:Autoantigens; D001798:Blood Proteins
Kompleksnoe immunokhimicheskoe issledovanie belkov plazmy krovi i rastvorimykh antigenov leĭkotsitov u bol'nykh ishemicheskoĭ bolezn'iu serdtsa pri gemoperfuzionnoĭ terapii.