Primary lymphomas of the major salivary glands.
The finding of a lymphoma of the major salivary glands (almost always parotid gland) has two diagnostic implications; it is only part of a known disseminated process, or it may be the first clinical-pathologic evidence of lymphoma. In the latter instance, the disease may be localized or, most often, be a precursory lesion to regional or systemic disease. Patients with Sjögren's or sicca syndrome are at increased risk for the development of lymphoma, and their lymphomas are biologically more aggressive.
D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000401:mortality; D012468:Salivary Gland Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000401:mortality; D012859:Sjogren's Syndrome / Q000150:complications / Q000276:immunology