title: [Brucella canis infection in man].
abstract: A Brucella canis infection, causing recurrent fever with so-called granulomatous hepatitis and splenomegaly, was detected serologically in a 30-year-old female patient. The disease originated in an infected dog from Greece which also showed a high titre. Following successful initial treatment with cotrimoxazole and streptomycin the disease broke out again on two further occasions. The infection was finally cured by 4-months continuous cotrimoxazole treatment after which the Brucella canis titre dropped from 1:1280 to 1:40 and then to zero. The patient has been symptom-free for the last two years.
mesh_terms: D000328:Adult; D000818:Animals; D000907:Antibodies, Bacterial / Q000302:isolation & purification; D002002:Brucella / Q000276:immunology; D002006:Brucellosis / Q000175:diagnosis* / Q000276:immunology / Q000662:veterinary; D004283:Dog Diseases / Q000276:immunology; D004285:Dogs; D005260:Female; D006505:Hepatitis / Q000209:etiology*; D006801:Humans; D013163:Splenomegaly / Q000209:etiology*; D015047:Zoonoses / Q000635:transmission
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: Brucella-canis-Infektion beim Menschen.