Tn polyagglutinability occurring in a patient with B cell lymphoma.
A case of polymorphic immunocytoma (B cell lymphoma) coinciding with expression of Tn antigen on a population of erythrocytes is presented. Tn activation was found incidentally by screening blood samples of patients suffering from hematologic malignancies with a Tn specific lectin from Salvia sclarea. So far, Tn activation has been reported only in apparently healthy subjects or in subjects suffering from or developing myeloid leukemia.
D000017:ABO Blood-Group System; D000368:Aged; D000743:Anemia, Hemolytic / Q000276:immunology; D000951:Antigens, Neoplasm / Q000276:immunology*; D015295:Antigens, Tumor-Associated, Carbohydrate; D001402:B-Lymphocytes; D005260:Female; D006384:Hemagglutination; D006801:Humans; D008223:Lymphoma / Q000276:immunology*; D012204:Rh-Hr Blood-Group System
D000017:ABO Blood-Group System; D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D012204:Rh-Hr Blood-Group System; C040286:Tn antigen