IgE antibodies against piperazine and N-methyl-piperazine in two asthmatic subjects.
The presence of specific IgE antibodies against conjugates between human serum albumin and piperazine, a compound previously known to cause occupational asthma, and N-methyl-piperazine, respectively, was demonstrated by RAST, RAST inhibition and skin prick tests in 2 asthmatic subjects occupationally exposed to these agents.
D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects; D001249:Asthma / Q000209:etiology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D008297:Male; D009784:Occupational Diseases / Q000209:etiology*; D000077489:Piperazine; D010879:Piperazines / Q000009:adverse effects / Q000276:immunology*; D011863:Radioimmunoassay; D012709:Serum Albumin / Q000276:immunology; D012882:Skin Tests
D000395:Air Pollutants, Occupational; D010879:Piperazines; D012709:Serum Albumin; D000077489:Piperazine; D007073:Immunoglobulin E; C048073:1-methylpiperazine