Danazol versus carbon dioxide laser plus postoperative danazol: treatment of infertility due to mild pelvic endometriosis.
The mechanism of action by which mild pelvic endometriosis causes infertility is still unknown. Danazol has been proposed as the sole agent to treat this condition; however, the results for pregnancy rates do not give as much cause for enthusiasm at the present time as they did when this drug was introduced. To ascertain the role of laser via the laparoscopic approach, this retrospective study looks at the pregnancy success rate in two groups of patients. Group I was treated with danazol alone; group II was treated with danazol after laser surgery. Although the success rate is better in group II, the population sample in both groups is modest and does not allow one to draw meaningful statistical conclusions at the present time, but the use of carbon dioxide laser with the laparoscope plus postoperative danazol seems to be a better approach to this condition that affects the infertile female.
D000328:Adult; D002245:Carbon Dioxide; D003131:Combined Modality Therapy; D003613:Danazol / Q000627:therapeutic use*; D004715:Endometriosis / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D053685:Laser Therapy; D010386:Pelvic Neoplasms / Q000150:complications*; D011182:Postoperative Care; D011245:Pregnadienes / Q000627:therapeutic use*; D011247:Pregnancy; D012189:Retrospective Studies; D013997:Time Factors
D011245:Pregnadienes; D002245:Carbon Dioxide; D003613:Danazol