title: [Granuloma anulare perforans: 2 clinically different forms].
abstract: Two different forms of granuloma annulare perforans are described. One form, which particularly affects young people, is characterized by small nodular lesions with central umbilication and a monomorphic clinical picture. These lesions can persist for many years, but spontaneous remission often occurs. The second form affects older patients. The clinical picture is polymorphic, consisting of dull red papules, umbilicated papules, pustular lesions and small atrophic scars. This form is resistant to a variety of therapies and does not heal spontaneously.
mesh_terms: D000368:Aged; D002648:Child; D003094:Collagen / Q000378:metabolism; D003238:Connective Tissue / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000473:pathology*; D006644:Histiocytes / Q000648:ultrastructure; D006801:Humans; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D012008:Recurrence; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology*
chemical_list: D003094:Collagen
vernacular_title: Granuloma anulare perforans: Zwei klinisch verschiedenartige Verlaufsformen.