Metabolism of n-alkanes and their incorporation into lipids in the rainbow trout.
The metabolic utilization by fish of n-alkanes was investigated in Salmo gairdneri R. receiving per os a single dose of [14C]heptadecane. This alkane was largely absorbed and radioactivity in the intestinal content was entirely in heptadecane. No elimination of the hydrocarbon was observed in urine. One week after dosing, ca. 50% of the ingested radioactivity was stored in the carcass and two-thirds of this radioactivity was due to heptadecane. The highest concentration of 14C was found in adipose tissue and liver, in which 77 and 22%, respectively, of the radioactivity originated from hydrocarbon. The rest was omega-oxidized to heptadecanoic acid. This fatty acid was incorporated into neutral lipids (mainly as free fatty acid) and phospholipids.
D000273:Adipose Tissue / Q000378:metabolism; D000473:Alkanes / Q000378:metabolism*; D000818:Animals; D005227:Fatty Acids / Q000378:metabolism; D008055:Lipids / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D010084:Oxidation-Reduction; D012487:Salmonidae / Q000378:metabolism*; D014018:Tissue Distribution; D014337:Trout / Q000378:metabolism*; D014873:Water Pollutants / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000378:metabolism*
D000473:Alkanes; D005227:Fatty Acids; D008055:Lipids; D014873:Water Pollutants; D014874:Water Pollutants, Chemical; C016486:heptadecane