Effects of MT-141, a new cephamycin antibiotic, on acute urinary tract infections.
The bacteriological efficacy of MT-141, a new cephamycin antibiotic, was compared with that of cefotaxime and latamoxef in women with acute simple urinary tract infections, to assess the rapid bactericidal properties of MT-141. MT-141 was less active in terms of its MICs than cefotaxime or latamoxef against the clinical isolates, but MT-141 brought about higher rates of decrease in bacterial counts than cefotaxime or latamoxef within the first hour after injection.
D000328:Adult; D000368:Aged; D002439:Cefotaxime / Q000627:therapeutic use; D002513:Cephamycins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009070:Moxalactam / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy*
D002513:Cephamycins; D002439:Cefotaxime; C046079:cefminox; D009070:Moxalactam