[Biosynthetic activity of cultures of different species of the genus Actinomadura].
The ability to synthesize antibiotics and exoproteases was studied in 13 species belonging to the Actinomadura genus. The antibiotic and proteolytic activities were found only in A. fulvescens INA-3321 and A. citrea INA-1849. Glycerol was shown to be the best carbon source for the growth and biosynthetic activity of A. fulvescens. A. citrea had a wider spectrum of carbon sources used for the growth and a higher proteolytic and antibiotic activity. A. citrea exerted the maximal biosynthetic activity and the best growth in a medium with starch and xylose. The effect of different nitrogen sources on the growth and biosynthetic activity of A. citrea was also studied.
D000192:Actinomycetales / Q000254:growth & development / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D002364:Caseins / Q000378:metabolism; D003470:Culture Media / Q000378:metabolism; D020689:Exopeptidases; D006863:Hydrogen-Ion Concentration; D010447:Peptide Hydrolases / Q000096:biosynthesis*; D013997:Time Factors
D000900:Anti-Bacterial Agents; D002364:Caseins; D003470:Culture Media; D020689:Exopeptidases; D010447:Peptide Hydrolases
Izuchenie biosinteticheskoĭ aktivnosti kul'tur raznykh vidov roda Actinomadura.