Nephrotic syndrome associated with hyper-high-density lipoproteinemia potentiated by prednisolone therapy.
We describe a case of nephrotic syndrome (idiopathic membranous glomerulonephropathy) with high serum HDL cholesterol (91 mg/100 ml) which increased to 240 mg/100 ml following steroid therapy. The increase in HDL was mainly a result of increased HDL2 and increased plasma apolipoprotein A-I.
D000328:Adult; D016632:Apolipoprotein A-I; D001054:Apolipoproteins A / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury; D008076:Cholesterol, HDL / Q000097:blood*; D006801:Humans; D006951:Hyperlipoproteinemias / Q000097:blood / Q000139:chemically induced / Q000150:complications*; D008107:Liver Diseases / Q000097:blood; D008297:Male; D009404:Nephrotic Syndrome / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000009:adverse effects* / Q000627:therapeutic use
D016632:Apolipoprotein A-I; D001054:Apolipoproteins A; D008076:Cholesterol, HDL; D011239:Prednisolone