Effect of intravenous fat emulsion on natural killer cellular function and antibody-dependent cell cytotoxicity.
Natural killer cell activity and antibody-dependent cellular cytotoxicity were measured in 12 surgical patients before and after a 24-h infusion of 1 litre of 20 per cent Intralipid. A further 12 patients received an equivalent amount of physiological saline and acted as controls. Neither Intralipid nor physiological saline had any effect upon natural killer cell activity or antibody-dependent cellular cytotoxicity under the conditions of this study.
D000328:Adult; D000368:Aged; D000920:Antibody-Dependent Cell Cytotoxicity / Q000187:drug effects*; D002460:Cell Line; D002860:Chromium Radioisotopes; D005069:Evaluation Studies as Topic; D005217:Fat Emulsions, Intravenous / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000276:immunology; D007951:Leukemia, Myeloid; D008223:Lymphoma; D008297:Male; D008875:Middle Aged; D010288:Parenteral Nutrition / Q000379:methods*; D010289:Parenteral Nutrition, Total / Q000379:methods*
D002860:Chromium Radioisotopes; D005217:Fat Emulsions, Intravenous