The effect of a single dose of aflatoxin B1 on the value of nucleolar index of blood lymphocytes and on histological changes in the liver, bursa Fabricii, suprarenal glands and spleen in ducklings.
The value of the nucleolar index of blood lymphocytes, as well as histopathological changes in liver, bursa Fabricii, suprarenal glands and spleen in ducklings administered per os a single dose of 1.5 micrograms aflatoxin B1 on the second day of their life, were observed for two weeks. There was a clear correlation observed between morphological changes in the lymphatic system organs and liver and the value of the nucleolar index of peripheral blood lymphocytes on the 13th and 14th day after administration of aflatoxin B1. The results obtained point to different susceptibility of the tested organs and lymphocytes to the action of aflatoxin B1.
D000311:Adrenal Glands / Q000473:pathology*; D016604:Aflatoxin B1; D000348:Aflatoxins / Q000008:administration & dosage* / Q000633:toxicity; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism; D002060:Bursa of Fabricius / Q000473:pathology; D002466:Cell Nucleolus / Q000187:drug effects*; D004334:Drug Administration Schedule; D004372:Ducks; D005260:Female; D008099:Liver / Q000473:pathology*; D008214:Lymphocytes / Q000187:drug effects / Q000473:pathology*; D013154:Spleen / Q000473:pathology
D000348:Aflatoxins; D016604:Aflatoxin B1