Thyrotropin-releasing hormone does not inhibit lysine vasopressin-induced growth hormone secretion in normal men.
In order to establish whether thyrotropin-releasing hormone (TRH) inhibits lysine-vasopressin (LVP)-induced growth hormone (GH) release, six normal men were tested with LVP alone or in combination with TRH. LVP strikingly increased serum GH levels; this response was not altered by TRH. These results indicate that in man TRH is not involved in the control of GH secretion in response to LVP.
D000328:Adult; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D006801:Humans; D008236:Lypressin / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D008297:Male; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000378:metabolism; D012636:Secretory Rate / Q000187:drug effects; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology* / Q000502:physiology
D008236:Lypressin; D013973:Thyrotropin-Releasing Hormone; D013006:Growth Hormone