title: [Morphofunctional changes in the cardiovascular system in nitroglycerin poisoning].
abstract: The cardiovascular system was examined in acute, subacute and chronic intoxications with nitroglycerin. It was revealed that morphofunctional alterations were uniform in nature, being more demonstrable in chronic exposure during 6 months. Myocardial alterations were characterized by disturbed hemodynamics, dystrophy, focal myocarditis, changes in the activity of enzymes, and changes in the electrocardio- and rheovasographic readings. Prolonged intoxication produced more profound and stable alterations.
mesh_terms: D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography; D006439:Hemodynamics / Q000187:drug effects; D006651:Histocytochemistry; D005996:Nitroglycerin / Q000506:poisoning*; D011817:Rabbits; D051381:Rats; D013997:Time Factors
chemical_list: D005996:Nitroglycerin
vernacular_title: Morfofunktsional'nye izmeneniia serdechno-sosudistoĭ sistemy pri intoksikatsii nitroglitserinom.