title: Structure of the capsular antigen of Neisseria meningitidis serogroup K.
abstract: The capsular antigen isolated from the culture liquid of a Neisseria meningitidis serogroup K(1811) fermentation consists of the 2-acetamido-2-deoxymannuronic acid disaccharide repeating unit as follows: ----3)-beta-D-ManpNAcA-(1----4)-beta-D-ManpNAcA-(1---- The polysaccharide is O-acetylated at the non-glycosylated C-4. Structural evidence has been obtained from sugar analysis, methylation analysis, as well as 1H and 13C NMR spectroscopy.
mesh_terms: D000942:Antigens, Bacterial; D002241:Carbohydrates / Q000032:analysis; D055598:Chemical Phenomena; D002621:Chemistry; D008401:Gas Chromatography-Mass Spectrometry; D006858:Hydrofluoric Acid; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D009345:Neisseria meningitidis / Q000145:classification / Q000276:immunology*; D010084:Oxidation-Reduction; D011135:Polysaccharides, Bacterial; D012703:Serotyping
chemical_list: D000942:Antigens, Bacterial; D002241:Carbohydrates; D011135:Polysaccharides, Bacterial; D006858:Hydrofluoric Acid