Muscle strength testing in Parkinson's disease.
Isotonic muscle strength measured by a quantitative technique was decreased in early Parkinson's disease compared to age-matched controls. Weakness was present both on the affected and unaffected side in hemiparkinsonism. Similar degrees of weakness occurred in limbs with tremor or rigidity. Muscle weakness appears to be a primary symptom of Parkinson's disease which may relate to disturbed motor programming due to basal ganglia dysfunction.
D001132:Arm; D006801:Humans; D007717:Knee; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D010300:Parkinson Disease / Q000503:physiopathology*; D014953:Wrist