Neural modulation of immune function.
In this report we review our hypotheses and approaches to the study of the relationship between the central nervous and immune systems. Discussed are results pertaining to the modulation of immune parameters resulting from perturbations of the brain employing electrolytic lesions and the neuroleptic 6-hydroxydopamine. Experiments describing the central and peripheral effects of serotonin on in vivo and in vitro immune responses are also discussed.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001921:Brain / Q000276:immunology* / Q000502:physiology; D004912:Erythrocytes / Q000378:metabolism; D006892:Hydroxydopamines / Q000494:pharmacology; D007032:Hypothalamus, Anterior / Q000502:physiology; D007109:Immunity; D007166:Immunosuppressive Agents / Q000502:physiology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D016627:Oxidopamine; D012701:Serotonin / Q000502:physiology; D012756:Sheep; D013154:Spleen / Q000166:cytology
D006892:Hydroxydopamines; D007166:Immunosuppressive Agents; D012701:Serotonin; D016627:Oxidopamine