[Modification of the saccharide structures of orosomucoid in rats stimulated by treatment with phenobarbital].
The administration of phenobarbital (80 mg/kg body weight for 3 days) increased the plasma orosomucoid level with dramatic alterations in the relative proportions of heteroglycans. A crossed immunoaffinoelectrophoresis with Con A revealed an increase of strongly reactive fractions with a concomitant decrease of non and weakly reactive fractions.
D000818:Animals; D003208:Concanavalin A; D007123:Immunoelectrophoresis, Two-Dimensional; D008297:Male; D009844:Oligosaccharides / Q000032:analysis*; D009961:Orosomucoid / Q000096:biosynthesis* / Q000302:isolation & purification; D010634:Phenobarbital / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D009844:Oligosaccharides; D009961:Orosomucoid; D003208:Concanavalin A; D010634:Phenobarbital
Modifications des structures glycanniques de l'orosomucoïde de rat provoquées par un traitement par le phénobarbital.