title: Massive osteolysis. A review of seven cases.
abstract: Seven cases of massive osteolysis are presented. The aetiology of this disease is as yet unknown; neither age nor sex seems to be a factor in its incidence, nor are standard bone grafts or radiotherapy successful methods of treatment. However, in this series, operation produced a satisfactory outcome for five patients at a mean follow-up of 17 years; in three of these patients a custom-built prosthesis was inserted, and in one a conventional bone graft was combined with intramedullary nailing.
mesh_terms: D000293:Adolescent; D000328:Adult; D000798:Angiomatosis / Q000150:complications*; D001859:Bone Neoplasms / Q000150:complications*; D001862:Bone Resorption / Q000150:complications*; D005260:Female; D005269:Femur; D005598:Fractures, Spontaneous / Q000209:etiology* / Q000601:surgery; D006801:Humans; D006811:Humerus; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy