Decreased duration of pentobarbital anesthesia and increased pentobarbital metabolism in immature rats perinatally exposed to cimetidine.
D000758:Anesthesia; D000818:Animals; D000831:Animals, Newborn / Q000502:physiology*; D002927:Cimetidine / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005260:Female; D005333:Fetus / Q000187:drug effects; D008297:Male; D008431:Maternal-Fetal Exchange; D008862:Microsomes, Liver / Q000187:drug effects; D010424:Pentobarbital / Q000378:metabolism* / Q000494:pharmacology; D011247:Pregnancy; D051381:Rats; D012737:Sex Factors
D002927:Cimetidine; D003577:Cytochrome P-450 Enzyme System; D010424:Pentobarbital