title: Immunologic mechanisms underlying sepsis in the critically ill surgical patient.
abstract: This article describes the range of immunologic abnormalities that follows accidental and operative trauma. The high rate of infection in critically ill postoperative patients may result from these abnormalities in host defense function. Means to recognize and correct the post-trauma immune deficiencies are discussed.
mesh_terms: D000758:Anesthesia / Q000009:adverse effects; D003422:Critical Care; D004734:Energy Metabolism; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007165:Immunosuppression Therapy; D007239:Infections / Q000209:etiology / Q000276:immunology*; D007249:Inflammation / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D012157:Mononuclear Phagocyte System / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D009748:Nutrition Disorders / Q000209:etiology / Q000276:immunology / Q000628:therapy; D009895:Opsonin Proteins / Q000097:blood; D010288:Parenteral Nutrition; D011183:Postoperative Complications; D012882:Skin Tests; D013530:Surgical Wound Infection / Q000097:blood / Q000276:immunology*
chemical_list: D009895:Opsonin Proteins