title: A two vector field model of limb regeneration and transplant phenomena.
abstract: We propose a new field description of limb regeneration in developmental biology. Central to our approach is the recognition of the importance of vector fields as descriptors in problems involving polarities or a sense of direction. In limb regeneration these vector fields represent the organisms sense of the distal direction, and its sense of the circumferential ordering of structures. Essentially all experimental results obtained to date are consistent with or explained by the model.
mesh_terms: D000557:Ambystoma; D000663:Amphibians; D000818:Animals; D004331:Drosophila melanogaster; D005121:Extremities / Q000502:physiology* / Q000637:transplantation; D007839:Functional Laterality / Q000502:physiology; D008954:Models, Biological; D009024:Morphogenesis; D012038:Regeneration