Correlation of methacholine-induced non-specific bronchial reactivity and cold air hyperventilation challenge.
The degree of bronchoconstriction seen with cold air hyperventilation challenge was determined in 48 adult subjects with known degrees of methacholine-induced bronchial reactivity. The degree of bronchial reactivity as determined by the cold air hyperventilation challenge significantly correlated with the non-specific bronchial reactivity determined by a methacholine inhalation challenge. Cold air hyperventilation challenge can accurately confirm the presence of reactive airway disease.
D000328:Adult; D001249:Asthma / Q000503:physiopathology; D001986:Bronchial Spasm / Q000139:chemically induced*; D003080:Cold Temperature; D005541:Forced Expiratory Volume; D006801:Humans; D006985:Hyperventilation / Q000209:etiology*; D008688:Methacholine Compounds / Q000494:pharmacology*
D008688:Methacholine Compounds