title: [Comparative effectiveness of the basic drugs used in rheumatoid arthritis (long-term randomized study)].
abstract: Study of the comparative efficacy of the basic slow-acting drugs for the treatment of rheumatoid arthritis permits considering randomization as necessary for obtaining objective data. It has been established that gold salts (chrisanol and myochrysin) are the most efficacious drugs for the treatment of RA. D-Penicillamine and delagil, in particular, are less efficacious. Administration of levamisole is rather dangerous because of the frequency and intensity of side effects.
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D002738:Chloroquine / Q000031:analogs & derivatives / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004112:Dimercaprol / Q000031:analogs & derivatives / Q000627:therapeutic use; D006046:Gold / Q000627:therapeutic use; D006052:Gold Sodium Thiomalate / Q000627:therapeutic use; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use; D050607:Organogold Compounds; D009942:Organometallic Compounds; D010396:Penicillamine / Q000627:therapeutic use; D020005:Propanols; D011897:Random Allocation; D013438:Sulfhydryl Compounds; D013997:Time Factors
chemical_list: D000893:Anti-Inflammatory Agents; D050607:Organogold Compounds; D009942:Organometallic Compounds; D020005:Propanols; D013438:Sulfhydryl Compounds; D004112:Dimercaprol; D006052:Gold Sodium Thiomalate; D007978:Levamisole; C023676:chloroquine diphosphate; D006046:Gold; D002738:Chloroquine; C013394:aurotioprol; D010396:Penicillamine
vernacular_title: Sravnitel'naia effektivnost' osnovnykh bazisnykh preparatov pri revmatoidnom artrite (dlitel'noe randomizirovannoe ispytanie).