Mapping genetic systems by the supratype method.
Kinship mapping and population supratypes provide information on order and relative genetic position of loci within a system too small to map by recombination. These methods are compared for the RH, beta-globin, HLA, and GM systems, where recombination between loci is estimated as 0.0002-0.0069. Supratype analysis does not appreciably improve kinship mapping. Mean recombination within systems appears to be 10(-4) morgans/kb, an order of magnitude greater than the average for the whole genome. Possible implications of this discrepancy are discussed.
D002874:Chromosome Mapping; D008040:Genetic Linkage; D005828:Genetics, Population; D005914:Globins / Q000235:genetics; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007074:Immunoglobulin G / Q000235:genetics; D008957:Models, Genetic; D012204:Rh-Hr Blood-Group System / Q000235:genetics
D006680:HLA Antigens; D007074:Immunoglobulin G; D012204:Rh-Hr Blood-Group System; D005914:Globins