The effects of physiological state and plane of nutrition on the concentrations of microsomal cytochromes and the omega-oxidation of fatty acids in various tissues of the sheep (Ovis aries).
The omega-oxidation activities and electron transport components of the microsomal fractions of tissues from pregnant, non-pregnant and lactating sheep on different planes of nutrition have been examined. Differences from the rat system were found, and between the non-pregnant and late pregnant sheep. The hepatic microsomal activity of omega-oxidation was approximately doubled by fasting for 5 days, but was unaltered by pregnancy or lactation per se. This increase was not caused by an increase in the specific activity of the omega-hydroxy fatty acid dehydrogenases. The results are discussed in relation to the glucose stresses of pregnancy in ruminants.
D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003573:Cytochrome b Group / Q000378:metabolism; D003580:Cytochromes / Q000378:metabolism*; D015786:Cytochromes b5; D004579:Electron Transport; D005215:Fasting; D005227:Fatty Acids / Q000378:metabolism*; D005260:Female; D007774:Lactation; D008861:Microsomes / Q000378:metabolism*; D008862:Microsomes, Liver / Q000378:metabolism; D009245:NADH Dehydrogenase / Q000378:metabolism; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D010084:Oxidation-Reduction; D011247:Pregnancy; D011270:Pregnancy, Animal; D012756:Sheep / Q000378:metabolism*; D014018:Tissue Distribution
D003573:Cytochrome b Group; D003580:Cytochromes; D005227:Fatty Acids; D015786:Cytochromes b5; D003577:Cytochrome P-450 Enzyme System; D009251:NADPH-Ferrihemoprotein Reductase; D009245:NADH Dehydrogenase