The prostaglandin H synthase-dependent activation of 2-aminofluorene to products mutagenic to S. typhimurium strains TA98 and TA98NR.
D000818:Animals; D001711:Biotransformation; D005449:Fluorenes / Q000378:metabolism / Q000633:toxicity*; D008297:Male; D008861:Microsomes / Q000378:metabolism; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens / Q000378:metabolism*; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D051381:Rats; D012486:Salmonella typhimurium / Q000235:genetics*; D012669:Seminal Vesicles / Q000378:metabolism
D005449:Fluorenes; D009153:Mutagens; C012177:2-aminofluorene; D011451:Prostaglandin-Endoperoxide Synthases