title: Experimental validation of sino-atrial conduction time using sinus node potential recording, right and left atrial continuous pacing method.
abstract: In an experimental study indirect sino-atrial conduction time (SACT) was measured, using continuous pacing method from right and left atrial sites, and compared with direct SACT obtained from sinus node potential recording, all the determination being done before and after autonomic blockade. The distance between the two sites of stimulation may be taken into account as a correction factor for SACT determination. The SACT obtained with sinus node potential technique is the same as the indirect SACT after autonomic blockade. These findings are valuable for SACT determination with transesophageal pacing method. Left atrial pacing, thus transesophageal pacing, is a valuable method in estimating the SACT, but a time correction and autonomic blockade is required in order to obtain a real value, eliminating the extrinsic influences.
mesh_terms: D000818:Animals; D016275:Atrial Function; D001285:Atropine / Q000494:pharmacology; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D004285:Dogs; D004562:Electrocardiography; D004947:Esophagus; D008564:Membrane Potentials / Q000187:drug effects; D011433:Propranolol / Q000494:pharmacology; D012848:Sinoatrial Block / Q000139:chemically induced / Q000503:physiopathology; D012849:Sinoatrial Node / Q000187:drug effects / Q000502:physiology*; D013997:Time Factors
chemical_list: D001285:Atropine; D011433:Propranolol