title: [Acid-base findings in the cerebrospinal fluid of premedicated patients].
abstract: Analysis of acid-base-metabolism in cerebrospinal fluid is not easy, because pO2, pCO2 and pH change already within a short time after sampling. Acid-base-values in CSF have been measured in 50 healthy patients within 20 seconds after withdrawal. Our results (pH 7.298 +/- 0.007; pCO2 46.94 +/- 4.84 mmHg; HCO3 22.78 +/- 2.15 mVal/l; BE-2.4 +/- 2.39 mVal/l; pO2 50.27 +/- 14.06 mmHg) demonstrate, that CSF is more acidic than often claimed. This is important, whenever possible precipitations by intrathecal injection of local anaesthetics are discussed.
mesh_terms: D000136:Acid-Base Equilibrium / Q000187:drug effects*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000775:Anesthesia, Spinal; D001639:Bicarbonates / Q000134:cerebrospinal fluid; D002245:Carbon Dioxide / Q000134:cerebrospinal fluid; D002555:Cerebrospinal Fluid / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000134:cerebrospinal fluid; D011229:Preanesthetic Medication; D012016:Reference Values
chemical_list: D001639:Bicarbonates; D002245:Carbon Dioxide; D010100:Oxygen
vernacular_title: Säure-Basen-Befunde im Liquor cerebrospinalis bei prämedizierten Patienten.