[Antidepressive prevention with lithium salts: possible interaction with occupational exposure to nephrotoxic substances].
Forty-four patients suffering from depressive disorders treated with lithium have been subdivide in two groups. One of groups included subjects with previous working anamnesis of exposure to renal toxic agents. The differences of renal function between the two groups have been considered. Significant differences of glomerular and tubular function have been found. These findings permit to hypothesize a synergism between lithium and nephrotoxic agents.
D000328:Adult; D003866:Depressive Disorder / Q000188:drug therapy*; D004347:Drug Interactions; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced*; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D016651:Lithium Carbonate; D008670:Metals / Q000009:adverse effects; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D010575:Pesticides / Q000009:adverse effects; D012997:Solvents / Q000009:adverse effects
D008670:Metals; D010575:Pesticides; D012997:Solvents; D016651:Lithium Carbonate; D008094:Lithium
Profilassi antidepressiva con sali di litio: possibile interazione con l'esposizione professionale a nefrotossici.