title: Galactosialidosis: low beta-galactosidase activity in serum after long-term clotting.
abstract: Serum beta-galactosidase activity was found to be markedly increased in clotting blood from normal subjects, but patients with galactosialidosis showed only a slight increase of this enzyme activity. Consequently, the beta-galactosidase activity was low in serum after long-term clotting in patients with this disease. The mechanism of the enzyme activation is unknown. The use of anticoagulants completely inhibited the activation.
mesh_terms: D005696:Galactosidases / Q000097:blood*; D005733:Gangliosidoses / Q000201:enzymology*; D006801:Humans; D001616:beta-Galactosidase / Q000097:blood*
chemical_list: D005696:Galactosidases; D001616:beta-Galactosidase