Pseudo-widening of cranial sutures as a feature of long-term prostaglandin E1 therapy.
Disturbance of desmogenous ossification of the skull is an extremely rare complication of long-term prostaglandin treatment. This report describes a newborn with pulmonary atresia, ventricular septal defect and ductus-dependent pulmonary blood flow in whom administration of prostaglandin E1 (PGE1) over a period of 96 days produced uncommon clinical and radiologic findings.
D003393:Cranial Sutures / Q000000981:diagnostic imaging / Q000187:drug effects*; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011458:Prostaglandins E / Q000009:adverse effects*; D011859:Radiography; D012886:Skull / Q000187:drug effects*
D011458:Prostaglandins E