title: [Genetic aspects of humoral immunity reactions to collagen in man and animals. III. An analysis of the sexual dimorphism of the levels of autoantibodies to collagen type I in systemic lupus erythematosus patients and their modifications in ontogeny].
abstract: The study of polymorphism levels of the autoantibodies to collagen type I in patients with systemic lupus erythematosus revealed the sex dimorphism of the character studied. Negative correlation of the levels of autoantibodies to collagen type I and those of sex hormones as well as modulation of the character under the action of xenobiotics were observed.
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000917:Antibody Formation; D001323:Autoantibodies / Q000032:analysis* / Q000235:genetics; D003094:Collagen / Q000235:genetics* / Q000276:immunology; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000235:genetics / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic; D012727:Sex Characteristics; D013739:Testosterone / Q000097:blood
chemical_list: D001323:Autoantibodies; D013739:Testosterone; D004958:Estradiol; D003094:Collagen
vernacular_title: Geneticheskie aspekty reaktsiĭ gumoral'nogo immuniteta k kollagenu u cheloveka i zhivotnykh. Soobshchenie III. Analiz polovogo dimorfizma urovneĭ autoantitel k kollagenu I tipa u bol'nykh sistemnoĭ krasnoĭ volchankoĭ i ikh modifikatsii v ontogeneze.