[State of confusion induced by valproic acid and reversed after administration of clonazepam].
A 20 year old woman with complex partial seizures from childhood developed a stuporous state when her anticonvulsant therapy was substituted by VPA. She recovered when treated orally with clonazepam. This case was compared with others in the literature for which the origin of the stuporous state have been hypothesized.
D000328:Adult; D001570:Benzodiazepinones / Q000627:therapeutic use*; D002998:Clonazepam / Q000008:administration & dosage / Q000627:therapeutic use*; D003072:Cognition Disorders / Q000139:chemically induced*; D003221:Confusion / Q000139:chemically induced*; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy*; D005260:Female; D006801:Humans; D014635:Valproic Acid / Q000008:administration & dosage / Q000009:adverse effects* / Q000037:antagonists & inhibitors
D001570:Benzodiazepinones; D002998:Clonazepam; D014635:Valproic Acid
Etat confusionnel sous acide valproïque réversible après administration de clonazepam.