title: [Septicemia caused by Pseudomonas aeruginosa serotype O 16 in a hemato-oncology department. Review of 17 cases].
abstract: Seventeen cases of Pseudomonas aeruginosa serotype O 16 septicaemia in patients with immune deficiencies are reported. All patients had a poor prognosis from the onset because of the advanced stage of their illness, the particular clinical form of their disease or because of the confirmed inefficacy of their anti-leukaemic chemotherapy. The neutrophil leukocyte count was less than 0.5 X 10(9)/l in all cases and 13 patients had also received wide-spectrum antibiotic therapy for at least 15 days. The septicaemia was accompanied by pelvic sepsis in 6 cases. The prognosis was very poor and 12 patients died rapidly in a state of shock. P. aeruginosa was an infrequent cause of infection during the 31 months period of observation but the O 16 serotype was the commonest in our department. The source of contamination seemed to be a chronic carrier state. P. aeruginosa is resistant to most of the antibiotics which would be expected to be effective.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001855:Bone Marrow Diseases / Q000150:complications*; D002648:Child; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007938:Leukemia / Q000150:complications*; D008223:Lymphoma / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications; D011379:Prognosis; D011552:Pseudomonas Infections / Q000209:etiology*; D011550:Pseudomonas aeruginosa / Q000145:classification; D018805:Sepsis / Q000175:diagnosis / Q000382:microbiology*; D012703:Serotyping; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Septicémie à Pseudomonas aeruginosa de sérotype O 16 dans un service d'hémato-oncologie. Revue de 17 cas.