title: Neonatal alloimmune thrombocytopenic purpura: a case report.
abstract: We report a case of a sibling pair with neonatal alloimmune thrombocytopenic purpura. Serial antepartum platelet alloantibody quantitation by an enzyme-linked immunoabsorbent assay revealed rising antibody titers during advancing gestation. We discuss the implications of this finding in the antepartum diagnosis of neonatal alloimmune thrombocytopenic purpura, a rare, but frequently fatal disorder.
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000276:immunology*; D001792:Blood Platelets / Q000276:immunology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007518:Isoantibodies / Q000032:analysis; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011696:Purpura, Thrombocytopenic / Q000276:immunology*
chemical_list: D007518:Isoantibodies