The ovine mammary gland as an experimental model to determine the virulence of animal ureaplasmas.
As an estimate of their virulence, the ability of ovine, bovine, canine, feline and simian ureaplasma strains to cause mastitis in the ovine mammary gland was investigated. Five ovine ureaplasmas produced a clinical mastitis. Broth cultures of seven bovine ureaplasmas were unable to infect the ovine gland, but two of these strains plus one other were able to do so following passage through the bovine udder. One of two canine strains and a feline strain both caused mastitis, but the simian strain persisted at low titre for only 5 days post-inoculation in one of the two ewes tested.
D000818:Animals; D002415:Cats; D002417:Cattle; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D000882:Haplorhini; D008321:Mammary Glands, Animal / Q000382:microbiology*; D008413:Mastitis / Q000382:microbiology*; D008892:Milk / Q000382:microbiology; D012756:Sheep; D014509:Ureaplasma / Q000472:pathogenicity*