Coma following ECT and intravenous droperidol: case report.
A 60-year-old man with psychotic depression became comatose following the administration of intravenous droperidol given for post-ECT delirious agitation. The differential diagnosis, which included neuroleptic malignant syndrome and the possibility that droperidol may have uniquely detrimental effects in the context of post-ECT delirium, are discussed. In light of recent publications advocating droperidol as the pharmacologic treatment of choice for severe agitation, this case illustrates a need for greater caution in its use for the treatment of post-ECT delirium.
D003128:Coma / Q000139:chemically induced*; D003693:Delirium / Q000188:drug therapy* / Q000209:etiology; D003866:Depressive Disorder / Q000628:therapy; D004329:Droperidol / Q000009:adverse effects*; D004565:Electroconvulsive Therapy / Q000009:adverse effects; D006801:Humans; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis; D011595:Psychomotor Agitation / Q000188:drug therapy / Q000209:etiology
D004329:Droperidol