Radiation inactivation of the human erythrocyte nucleoside and glucose transporters.
The human erythrocyte nucleoside and glucose transporters, identified previously as band 4.5 peptides (apparent Mr 66 000-45 000) on SDS-polyacrylamide gels, have been characterized in situ by radiation inactivation analysis. Target size analysis of lyophilized membranes indicates an apparent Mr of 110 000 +/- 12 000 and 124 000 +/- 11 000 for the nucleoside and glucose carriers, respectively. These data suggest that both transporters exist in the membrane as dimers.
D001798:Blood Proteins / Q000378:metabolism / Q000528:radiation effects*; D002352:Carrier Proteins / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004910:Erythrocyte Membrane / Q000378:metabolism / Q000528:radiation effects*; D006801:Humans; D008565:Membrane Proteins / Q000378:metabolism / Q000528:radiation effects*; D009004:Monosaccharide Transport Proteins / Q000097:blood / Q000528:radiation effects*; D033703:Nucleoside Transport Proteins; D010315:Particle Accelerators
D001798:Blood Proteins; D002352:Carrier Proteins; D008565:Membrane Proteins; D009004:Monosaccharide Transport Proteins; D033703:Nucleoside Transport Proteins