title: Three-dimensional structure of a specific pre-messenger RNP particle established by electron microscope tomography.
abstract: Electron microscope tomography has been used to refine the structural analysis of individual RNP particles synthesized on Balbiani ring genes in Chironomus tentans. The spherical particles have a diameter of 500 A and are composed of a thick RNP ribbon bent into an asymmetrical, four-domain, ring-like configuration. The first domain, containing the 5' end of the transcript, and the fourth domain, containing the 3' end, are close to each other.
mesh_terms: D000818:Animals; D002683:Chironomidae; D008854:Microscopy, Electron / Q000379:methods; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D011487:Protein Conformation; D011498:Protein Precursors; D012261:Ribonucleoproteins; D012469:Salivary Glands
chemical_list: D011498:Protein Precursors; D012261:Ribonucleoproteins; C026452:messenger ribonucleoprotein