[Combined therapy of gastric cancer].
For the patients with advanced gastric cancer extended surgery contributed for improvement of end-result. As systemic cancer chemotherapy was not so effective, targeted cancer chemotherapy for lymph node metastasis and carcinomatous peritonitis was carried out by modification of drug dosage form as fat emulsion and activated carbon incorporating anticancer agent. Anticancer agents were delivered to those metastatic foci with high drug concentration. Preoperative irradiation for gastric cancer did not contributed for improvement of end-result after surgery. Hyperthermia therapy with chemotherapy for carcinomatous peritonitis and hormonal therapy with anti-estrogenic agent for scirrhous cancer were attempted as combined modality for gastric cancer.
D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004655:Emulsions; D005743:Gastrectomy; D006801:Humans; D006979:Hyperthermia, Induced; D016685:Mitomycin; D008937:Mitomycins / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D013629:Tamoxifen / Q000627:therapeutic use
D000903:Antibiotics, Antineoplastic; D004655:Emulsions; D008937:Mitomycins; D013629:Tamoxifen; D016685:Mitomycin