An extension of Green and Woodrow's sibling method for detecting MHC-disease associations.
When a number of families can be identified with two or more siblings having a particular disease, Green & Woodrow proposed a test for MHC-disease association. An extension of this test is presented to detect more general associations when family sizes exceed three.
D000483:Alleles; D002648:Child; D003433:Crosses, Genetic; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D007154:Immune System Diseases / Q000235:genetics*; D008285:Major Histocompatibility Complex; D008297:Male; D008957:Models, Genetic