title: [Changes in the structural function of the membrane of M. lysodeikticus as affected by preparations of the bacterial autoregulatory factors D1].
abstract: Introduction of factors D1 isolated from the culture fluids of B. cereus and Ps. carboxydoflava into cytoplasmic membranes of M. lysodeikticus resulted in a higher microviscosity of the lipid phase. Factor d1 changes the ion permeability of an artificial bilayer membrane as well as reduces the content of free water in the bacterial paste. It is assumed that registered structural changes may result from the interaction of the factor molecules with membrane lipids and be the main reason of changes in the functioning of membrane-bound enzymes and dehydration of the microbial cell as well.
mesh_terms: D001409:Bacillus cereus / Q000502:physiology*; D002462:Cell Membrane / Q000187:drug effects / Q000648:ultrastructure; D002463:Cell Membrane Permeability / Q000187:drug effects; D004347:Drug Interactions; D006706:Homeostasis / Q000187:drug effects; D008051:Lipid Bilayers / Q000494:pharmacology; D008563:Membrane Lipids / Q000494:pharmacology; D008837:Micrococcus / Q000187:drug effects* / Q000648:ultrastructure; D011549:Pseudomonas / Q000502:physiology*; D014783:Viscosity
chemical_list: D008051:Lipid Bilayers; D008563:Membrane Lipids
vernacular_title: Izmenenie strukturnogo sostoianiia membrany M. lysodeikticus pod vliianiem preparatov autoreguliatornykh bakterial'nykh faktorov D1.