Intracranial and intraspinal dissemination from a growth hormone-secreting pituitary tumor. Case report.
A 48-year-old woman developed multiple intracranial and intraspinal metastases from an invasive growth hormone-secreting pituitary adenoma after surgery and radiation therapy. This is the first reported case to show that the cells in the metastatic tumors and in the cerebrospinal fluid contained growth hormone.
D000236:Adenoma / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary* / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000556:secondary* / Q000601:surgery; D005260:Female; D005625:Frontal Lobe; D013006:Growth Hormone / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D013702:Temporal Lobe; D014057:Tomography, X-Ray Computed
D013006:Growth Hormone