A discrete lesion of ventral hypothalamus and optic chiasm that disturbed the daily temperature rhythm.
A patient with a discrete metastasis in the ventral hypothalamus and optic chiasm is reported, who developed an abnormal daily rhythm of oral temperature without alteration of the 24-h mean temperature. This region, its afferents, and its efferents appear to be important in the neural regulation of human circadian rhythmicity.
D000230:Adenocarcinoma / Q000503:physiopathology / Q000556:secondary*; D001833:Body Temperature Regulation; D002940:Circadian Rhythm; D003390:Cranial Nerve Neoplasms / Q000503:physiopathology / Q000556:secondary*; D005260:Female; D006801:Humans; D007029:Hypothalamic Neoplasms / Q000503:physiopathology / Q000556:secondary*; D007031:Hypothalamus / Q000503:physiopathology*; D008875:Middle Aged; D009897:Optic Chiasm / Q000503:physiopathology*; D010904:Pituitary Gland, Posterior / Q000503:physiopathology; D010911:Pituitary Neoplasms / Q000503:physiopathology / Q000556:secondary; D012004:Rectal Neoplasms / Q000503:physiopathology*; D013493:Suprachiasmatic Nucleus / Q000503:physiopathology