Target fibers in multiple sclerosis: implications for pathogenesis.
Target fibers are generally considered a specific indicator of denervating disease. We found large numbers of target fibers in a biceps biopsy from a patient with MS and spastic quadriparesis. There was no evidence of denervation. Target fibers are not seen only in denervation.
D000328:Adult; D003714:Denervation; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000473:pathology*; D009132:Muscles / Q000473:pathology*