title: [Primary, exclusively gastric localization of alpha-chain disease: anatomo-clinical and immunohistochemical study].
abstract: We report the first case of heavy alpha-chain disease exclusively located in the stomach and in the perigastric nodes in a thirty year old Tunisian patient. Both the small bowel and the mesenteric nodes were evaluated histologically and immunochemically and were found to be free of disease. Complete remission was obtained using chemotherapy. The reasons for which the small intestinal mucosa and the mesenteric nodes, nearly constantly involved, in alpha-chain disease were spared in our case, are discussed.
mesh_terms: D000328:Adult; D006362:Heavy Chain Disease / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007137:Immunoglobulin alpha-Chains; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D013272:Stomach Diseases / Q000276:immunology* / Q000473:pathology
chemical_list: D007137:Immunoglobulin alpha-Chains
vernacular_title: Localisation gastrique primitive et exclusive d'une maladie des chaînes alpha: étude anatomo-clinique et immuno-histochimique.