Evidence for interferon (IFN) induction in mice and humans by a fraction of bacterial extracts (SLO4) in vitro and after oral administration in vivo.
D015088:2',5'-Oligoadenylate Synthetase / Q000097:blood; D000284:Administration, Oral; D000818:Animals; D002478:Cells, Cultured; D004926:Escherichia coli / Q000502:physiology*; D005260:Female; D006801:Humans; D007369:Interferon Inducers; D007370:Interferon Type I / Q000096:biosynthesis*; D007371:Interferon-gamma / Q000096:biosynthesis*; D007700:Kinetics; D007711:Klebsiella pneumoniae / Q000502:physiology*; D007962:Leukocytes / Q000201:enzymology / Q000276:immunology / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D013997:Time Factors
D007369:Interferon Inducers; D007370:Interferon Type I; D007371:Interferon-gamma; D015088:2',5'-Oligoadenylate Synthetase