The effect of acute anoxia on ventricular monophasic action potential. Experimental study.
Acute hypoxia induced in dogs by breath stopping produces a significant increase of ventricular epicardial monophasic action potential duration, thus an increase in myocardial refractoriness. This may be an explanation of the effect of breath holding test in terminating reentrant cardiac arrhythmias.
D000200:Action Potentials; D000208:Acute Disease; D000818:Animals; D004285:Dogs; D006321:Heart / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology*; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure
D010100:Oxygen