Relationship between human serum placental alkaline phosphatase and the ABo and Rh compatibility status in pregnancy.
458 unrelated healthy women at various gestational ages were examined for serum heat-stable alkaline phosphatase (HSALP) activity. The sample was subdivided into four groups according to the compatibility mating type in the ABO and Rh systems: double compatible, ABO incompatible, Rh incompatible and double incompatible. The results confirm the exponential growth of serum placental isoenzyme as a function of gestational age and show that the moment of appearance of the placental isoenzyme is six weeks earlier in double incompatible matings.
D000017:ABO Blood-Group System; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D001787:Blood Group Incompatibility / Q000201:enzymology*; D005260:Female; D058851:GPI-Linked Proteins; D005865:Gestational Age; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008297:Male; D010920:Placenta / Q000201:enzymology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000201:enzymology*; D012204:Rh-Hr Blood-Group System
D000017:ABO Blood-Group System; D058851:GPI-Linked Proteins; D007527:Isoenzymes; D012204:Rh-Hr Blood-Group System; D000469:Alkaline Phosphatase; C019839:alkaline phosphatase, placental