Vasopressin-induced pressor responses in rats to bilateral electrolytic lesioning of the caudal portion of the nucleus tractus solitarii.
Bilateral electrolytic lesioning of the nucleus tractus solitarii elicited a pressor response in rats with spinal transection. This response was abolished by a vasopressin pressor antagonist and plasma vasopressin was increased during the response. This evidence suggests that the nucleus tractus solitarii is involved in inhibiting vasopressin release and that an impaired function would lead to an enhancement of vasopressin release, to the extent of eliciting a pressor response.
D000818:Animals; D001127:Arginine Vasopressin / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D001794:Blood Pressure; D001931:Brain Mapping; D008526:Medulla Oblongata / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains
D001127:Arginine Vasopressin