A model for the kinetics of potassium in healthy humans.
A model is developed to describe the distribution and excretion of potassium at arbitrary times during or after intake by ingestion or injection. The movement of K is tracked in greater detail than in previous models and is described in terms of anatomical compartments rather than the hypothetical, mathematically derived pools often considered. Parameter values are derived for a typical resting healthy adult male. Because of its anatomically realistic framework, the model may be used as a point of departure for modelling the behaviour of K in various subgroups of the population under less ideal conditions.
D000328:Adult; D001842:Bone and Bones / Q000378:metabolism; D004064:Digestive System / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008168:Lung / Q000378:metabolism; D008297:Male; D008954:Models, Biological; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*; D012016:Reference Values; D012039:Regional Blood Flow; D014018:Tissue Distribution
D011188:Potassium