Demonstration of retinoic acid isomers in human urine under physiological conditions.
Untransformed retinoic acid has never been demonstrated in human excreta under normal physiological conditions. We have developed a two-step liquid chromatographic system for the demonstration of subnanogram amounts of this compound in human urine without administration of any precursor.
D000328:Adult; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D007536:Isomerism; D008297:Male; D014212:Tretinoin / Q000652:urine*
D014212:Tretinoin