[Stimulating effect of aminoethylisothiuronium on the immune response and interferonogenesis in irradiated mice].
Aminoethylisothiuronium (AET) stimulated the formation of antibodies against sheep erythrocytes, not against E. coli, in X-irradiated (4 Gy) mice. The serum containing AET-induced interferon had the same effect. AET also promoted the rejection of the allogenic skin graft in mice irradiated with the same dose. In addition, AET and cystaphos stimulated the induction of interferon by the Newcastle disease virus in mice exposed to doses of 4, 5 or 6 Gy.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D003539:Cystaphos / Q000494:pharmacology; D007369:Interferon Inducers / Q000494:pharmacology*; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000276:immunology*; D013268:Stimulation, Chemical; D000338:beta-Aminoethyl Isothiourea / Q000494:pharmacology*
D007369:Interferon Inducers; D000338:beta-Aminoethyl Isothiourea; D003539:Cystaphos
Stimuliruiushches deĭstvie aminoétilizotiuroniia na immune reaktsii i interferonogenez u obluchennykh mysheĭ.