Critical micelle concentrations of lipoteichoic acids.
Purified lipoteichoic acids (LTAs) from several gram-positive organisms have been shown, by methods involving spectral changes of an added merocyanine dye probe, to have critical micelle concentrations in the range of 1 to 10 micrograms/ml, suggesting that acylated LTAs in their monomer forms may represent the major configuration of extracellular LTAs in bacterial culture fluids. The critical micelle concentrations obtained did not differ markedly with degree of carbohydrate substitution of the polymers. The significance of these findings in relation to the biological properties of LTA is discussed.
D000165:Acridine Orange; D003102:Colloids; D005453:Fluorescence; D008051:Lipid Bilayers / Q000378:metabolism; D008070:Lipopolysaccharides; D008823:Micelles; D010712:Phosphatidic Acids / Q000502:physiology; D011744:Pyrimidinones; D013053:Spectrophotometry; D013682:Teichoic Acids / Q000502:physiology; D014048:Tolonium Chloride
D003102:Colloids; D008051:Lipid Bilayers; D008070:Lipopolysaccharides; D008823:Micelles; D010712:Phosphatidic Acids; D011744:Pyrimidinones; D013682:Teichoic Acids; D014048:Tolonium Chloride; C009900:lipoteichoic acid; C003954:merocyanine dye; D000165:Acridine Orange