Metoclopramide-induced phantom dyskinesia.
A 58-year-old woman was receiving chemotherapy for carcinoma of the breast. She was given 1,700 mg metoclopramide IV for 2 months to prevent nausea and vomiting. Within hours after metoclopramide was given, she had hand tremor, akathisia, and truncal and orofacial dyskinesia. These symptoms resolved, but she was left with persistent shoulder stump chorea, the perception of the phantom left arm involuntarily adducted at the shoulder and flexed at the elbow, and dystonic pronation and extension of the hand away from her body. The motor aspects of the phantom dyskinesia will be emphasized.
D000671:Amputation, Surgical; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery; D004409:Dyskinesia, Drug-Induced / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008408:Mastectomy; D008787:Metoclopramide / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D009325:Nausea / Q000517:prevention & control; D010591:Phantom Limb / Q000503:physiopathology*; D012782:Shoulder / Q000601:surgery
D008787:Metoclopramide