California serogroup virus infection in a horse with encephalitis.
A 4-fold or greater seroconversion to the snowshoe hare serotype of the California serogroup of viruses in a horse with acute encephalitis was demonstrated by hemagglutination-inhibition, complement-fixation, and neutralization tests. The horse had a mild fever, was ataxic, had a head tilt, and was observed to circle. Chloramphenicol, dexamethasone, and B complex vitamins were administered and the horse recovered. The snowshoe hare virus is a recognized human pathogen, but it has not been associated with disease in horses. It is unknown whether horses play a role as amplification hosts for the snowshoe hare virus in nature, and further studies appear indicated.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002043:Bunyaviridae / Q000276:immunology*; D003168:Complement Fixation Tests / Q000662:veterinary; D002141:Encephalitis Virus, California / Q000276:immunology*; D004671:Encephalitis, Arbovirus / Q000662:veterinary*; D004670:Encephalitis, California / Q000175:diagnosis / Q000662:veterinary*; D006385:Hemagglutination Inhibition Tests / Q000662:veterinary; D006734:Horse Diseases / Q000175:diagnosis*; D006736:Horses; D008297:Male; D009500:Neutralization Tests
D000914:Antibodies, Viral