title: Screening for the potential pulmonary embolism victim.
abstract: The venous hemodynamics of 134 legs were evaluated using a bilateral impedance plethysmograph. Calf venous outflow following the release of proximal occluding cuffs and calf volume changes with ventilation were compared with the results of venography. We found that a two-second outflow of at least 65% indicated a patent deep venous system while an outflow of 50% or less indicated an obstruction of the proximal deep venous system. With outflow between 50% and 65%, a ventilatory wave height greater than 3 mm ruled out proximal deep venous obstruction while a height of 3 mm or less was not diagnostic. These two criteria yielded an accuracy of 92% with no false-negative results and a false-positive rate of only 10%. Thus, this technique can accurately rule out proximal deep venous obstruction and give the clinician considerable confidence in initiating anticoagulant therapy on those suspected cases with positive studies.
mesh_terms: D005188:False Negative Reactions; D005189:False Positive Reactions; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008403:Mass Screening / Q000379:methods; D010992:Plethysmography, Impedance; D011655:Pulmonary Embolism / Q000209:etiology / Q000517:prevention & control*; D012039:Regional Blood Flow; D012306:Risk; D013924:Thrombophlebitis / Q000150:complications / Q000175:diagnosis*