title: Magnetic resonance imaging and characterization of normal and abnormal intracranial cerebrospinal fluid (CSF) spaces.
abstract: A retrospective review of twenty-five normal MRI brain studies performed with the spin-echo technique focused special attention on the ventricular and extraventricular cerebrospinal fluid (CSF) and revealed unique signal intensity characteristics in the two locations. In addition, MRI studies of ten patients with abnormal extraaxial fluid collections either missed with CT or indistinguishable from CSF on CT images were also analyzed. MRI is more sensitive when compared to CT in evaluating the composition of CSF. Unique signal intensity characterizes the two major CSF compartments and presumably reflects their known but subtle difference in protein concentration (10-15 mg%). Normal variant or abnormal developmental fluid collections can be better characterized with MRI than with CT. These preliminary observations are offered in view of their implications for patient management and suggest further investigation.
mesh_terms: D001921:Brain / Q000033:anatomy & histology*; D001927:Brain Diseases / Q000175:diagnosis*; D002552:Cerebral Ventricles / Q000033:anatomy & histology*; D002555:Cerebrospinal Fluid; D003560:Cysts / Q000175:diagnosis; D004652:Empty Sella Syndrome / Q000175:diagnosis; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D014057:Tomography, X-Ray Computed