title: Effect of profound hypothermia on leukocytes and platelets.
abstract: Seventeen patients who underwent aortic arch replacement were subjected to profound hypothermia and circulatory arrest. At maximum cooling, platelet count dropped from 184 +/- 122 to 37 +/- 30 thousand per microliter, and the total leukocytic count fell from 6.27 +/- 4.0 to 1.47 +/- 0.6 thousand per microliter. The thrombocytopenia was partially reversed with rewarming. The total white cell count consistently returned to precooling values or higher (10.5 +/- 4.0). The mechanism for this cold induced phenomenon is not well understood.
mesh_terms: D001013:Aorta, Thoracic / Q000601:surgery; D001014:Aortic Aneurysm / Q000601:surgery; D001792:Blood Platelets / Q000166:cytology*; D006358:Hot Temperature; D006801:Humans; D007035:Hypothermia / Q000097:blood*; D007958:Leukocyte Count; D007962:Leukocytes / Q000166:cytology*; D010976:Platelet Count