Use of fab fragments of digoxin-specific antibodies in the therapy of massive digoxin poisoning.
A case of massive digoxin ingestion with multiple arrhythmias, consisting of high grade A-V block and ventricular ectopy not responsive to lidocaine, is described. The arrhythmias ceased following administration of digoxin-specific Fab fragments. The patient improved and was transferred to the psychiatric unit.
D000906:Antibodies; D004077:Digoxin / Q000506:poisoning*; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments; D007167:Immunotherapy; D008875:Middle Aged; D011041:Poisoning / Q000628:therapy*; D019966:Substance-Related Disorders / Q000628:therapy
D000906:Antibodies; D007140:Immunoglobulin Fab Fragments; D004077:Digoxin