Treatment with stanozolol before thrombolysis in patients with arterial occlusions.
The administration of the anabolic steroid stanozolol during 7, 8 days as pretreatment before thrombolytic therapy of acute or subacute arterial occlusions enhances the fibrinolytic potential significantly. On average the plasminogen increased from 101% to 133%, the euglobulin lysis time after venous stasis was shortened and the alpha 2-antiplasmin remained constant. This effect could be favourable to prepare patients undergoing thrombolytic treatment.
D000368:Aged; D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D005342:Fibrinolysis / Q000187:drug effects; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010958:Plasminogen / Q000032:analysis; D011292:Premedication; D013197:Stanozolol / Q000627:therapeutic use*; D000979:alpha-2-Antiplasmin / Q000032:analysis
D005343:Fibrinolytic Agents; D000979:alpha-2-Antiplasmin; D013197:Stanozolol; D010958:Plasminogen