title: The pharmacokinetics of oral and intravenous prenalterol in young, healthy volunteers.
abstract: The pharmacokinetics of prenalterol in healthy young volunteers after i.v. and oral dosing has been studied. There is evidence of non-linearity following the i.v. dosing. Evidence of dose-dependent pharmacokinetics following i.v. dosing has been obtained. The sustained-release formulation is very effective: almost 12 h were needed to achieve 50 per cent of the total AUC.
mesh_terms: D000284:Administration, Oral; D000328:Adult; D003692:Delayed-Action Preparations; D006801:Humans; D007275:Injections, Intravenous; D007700:Kinetics; D008297:Male; D011217:Practolol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000378:metabolism; D011294:Prenalterol
chemical_list: D003692:Delayed-Action Preparations; D011294:Prenalterol; D011217:Practolol