title: [Microcirculation in rheumatic mitral stenosis (clinico-morphological research by lung biopsies)].
abstract: The study of the microcirculation in lung and visceral pleura biopsies from patients with rheumatic mitral stenosis showed the involvement of all parts of the microcirculatory system including intra- and extravascular alterations and changes of the vascular wall as well as its lymphatic part. As the pressure in the small circulation circle increased and arterial hypertension established enhancement of the vascular reconstruction, rheological disturbances and dyscoagulation in the pulmonary microvessels took place. All this resulted in hemodynamic and metabolic homeostasis disturbances in the pulmonary artery system and, consequently, in the establishment of lung hypertension.
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000503:physiopathology; D008168:Lung / Q000098:blood supply* / Q000503:physiopathology; D008297:Male; D008833:Microcirculation / Q000503:physiopathology; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000503:physiopathology*; D011652:Pulmonary Circulation; D012214:Rheumatic Heart Disease / Q000503:physiopathology*
vernacular_title: Mikrotsirkuliatsiia pri revmaticheskom mitral'nom stenoze (kliniko-morfologicheskoe issledovanie po bioptatam legkikh).