title: Measurement of urinary chloride with the Kodak Ektachem 400.
abstract: Urinary chloride can be measured simply, precisely, and accurately with the Ektachem 400 clinical chemistry analyzer. Because the coated film technique used in this instrument requires the presence of a protein matrix, we added a protein-based calibrator to the urine samples to overcome the low protein concentration in these specimens. Its advantages over a coulometric titration method (Astra analyzer) include the extension of the range of linearity to lower concentrations and the absence of interference from prednisone metabolites in urine. A disadvantage is the negative bias interference of allopurinol.
mesh_terms: D001322:Autoanalysis / Q000295:instrumentation; D002712:Chlorides / Q000652:urine*; D004563:Electrochemistry; D006801:Humans
chemical_list: D002712:Chlorides