Soda lime adsorption of isoflurane and enflurane.
The authors demonstrated that soda lime will adsorb enflurane or isoflurane as a function of the water content of the soda lime. Various volumes of liquid enflurane or isoflurane were placed in an equilibration flask containing fresh (15% water by weight) or dried soda lime and the vapor phase anesthetic concentrations plotted. When dry soda lime was used, the plot of concentration as a function of volume of liquid added was biphasic: initially flat and then rising linearly. This is qualitatively similar to data reported previously for halothane. The authors hypothesize that drying soda lime produces a molecular sieve-like structure, as adsorption is greatest for molecules with small carbon chain lengths and kinetic diameters, or with structural characteristics such as cis/trans isomerism, which effectively reduce molecular size.
D000327:Adsorption; D000777:Anesthetics; D017610:Calcium Compounds; D004737:Enflurane; D007530:Isoflurane; D008738:Methyl Ethers; D008958:Models, Molecular; D010087:Oxides; D055585:Physical Phenomena; D010825:Physics; D012972:Sodium Hydroxide
D000777:Anesthetics; D017610:Calcium Compounds; D008738:Methyl Ethers; D010087:Oxides; C004569:soda lime; D012972:Sodium Hydroxide; D004737:Enflurane; D007530:Isoflurane