Early receptor potential recordings for clinical routine.
An apparatus and an electrode for early receptor potential recordings in clinical routine are introduced. One-hundred and eighty normal eyes were compared with cases of diffuse and localized retinal diseases. In retinitis pigmentosa patients a decrease in R1 and R2 amplitudes and in some cases a much faster time course was found. Eyes with circumscribed retinal affectations produced a wide variety of amplitudes, overlapping with the range of normals. In cases of monochromatism, the ERP recording established the diagnosis because of an absent R1 wave.
D004594:Electrophysiology / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010786:Photoreceptor Cells / Q000502:physiology* / Q000503:physiopathology; D012164:Retinal Diseases / Q000503:physiopathology