Multiple cancers in a Turner's syndrome with 45,X/46,XXp-/46,XX/47,XXX karyotype.
A female patient with a clinical picture of Turner's syndrome had five separate malignant tumors (three squamous cell carcinomas of the tongue, a colon cancer, and a glioblastoma multiforme). Her peripheral blood cells showed a 45,X/46,XXp-/46,XX/47,XXX mosaicism. The findings are discussed in relation to other extragonadal tumors in Turner's syndrome reported to-date.
D000368:Aged; D001853:Bone Marrow / Q000473:pathology; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D014424:Turner Syndrome / Q000235:genetics*