Diltiazem prevents the damage to cultured aortic smooth muscle cells induced by hyperlipidemic serum.
Diltiazem, a calcium antagonist, significantly reduced the increased 45Ca uptake and the number of dead cells in cultured aortic smooth muscle cells induced by hyperlipidemic serum.
D000818:Animals; D001011:Aorta / Q000166:cytology*; D001552:Benzazepines / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003470:Culture Media; D004110:Diltiazem / Q000494:pharmacology*; D006949:Hyperlipidemias / Q000097:blood*; D007700:Kinetics; D009131:Muscle, Smooth, Vascular / Q000166:cytology*; D011817:Rabbits
D001552:Benzazepines; D003470:Culture Media; D004110:Diltiazem