Enhanced toxicity of acetaminophen in alcoholics: report of three cases.
Severe intoxication from excessive acetaminophen without suicidal intent occurred in three patients, all alcohol abusers, one with evidence of underlying cirrhosis. Apparently, acetaminophen toxicity may be enhanced by alcohol.
D000082:Acetaminophen / Q000008:administration & dosage / Q000494:pharmacology / Q000506:poisoning*; D000328:Adult; D000437:Alcoholism / Q000150:complications*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D004347:Drug Interactions; D000431:Ethanol / Q000494:pharmacology; D006801:Humans; D008099:Liver / Q000473:pathology; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D008297:Male; D010195:Pancreatitis / Q000150:complications; D019966:Substance-Related Disorders
D000082:Acetaminophen; D000431:Ethanol