title: Buprenorphine-supplemented anaesthesia. Influence of dose on duration of analgesia after cholecystectomy.
abstract: Fifty-one patients undergoing cholecystectomy received a single dose of buprenorphine 4.5-12 micrograms kg-1 at induction. Median duration of analgesia after surgery was 6 h. Multiple regression analysis showed the duration of analgesia to be slightly dependent on the age of the patient. No relationship was found between the duration of analgesia and the weight-related dose of buprenorphine, the age, sex or body weight of the patient, the duration of anaesthesia, or the dose of droperidol or thiopentone administered.
mesh_terms: D000759:Adjuvants, Anesthesia; D000328:Adult; D000368:Aged; D000768:Anesthesia, General; D002047:Buprenorphine / Q000008:administration & dosage; D002763:Cholecystectomy; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009019:Morphinans / Q000008:administration & dosage; D010149:Postoperative Pain / Q000517:prevention & control; D012044:Regression Analysis; D013997:Time Factors
chemical_list: D000759:Adjuvants, Anesthesia; D009019:Morphinans; D002047:Buprenorphine