The effect of castration, testosterone and estradiol on 14C-serotonin metabolism by organ cultures of male rat pineal glands.
The pineal gland of the male rat does not appear to rely on prior conversion of testosterone to estradiol for the stimulant effect of testosterone on pineal melatonin and 5-methoxytryptophol synthesis.
D000818:Animals; D002369:Castration; D004958:Estradiol / Q000494:pharmacology*; D007211:Indoles / Q000378:metabolism; D008297:Male; D008550:Melatonin / Q000096:biosynthesis; D009924:Organ Culture Techniques; D010870:Pineal Gland / Q000378:metabolism*; D051381:Rats; D012701:Serotonin / Q000378:metabolism*; D013739:Testosterone / Q000494:pharmacology*
D007211:Indoles; D012701:Serotonin; D013739:Testosterone; D004958:Estradiol; C002465:methoxytryptophol; D008550:Melatonin