Successful management of Histoplasma capsulatum infection of an abdominal aortic aneurysm.
A 65-year-old woman with disseminated histoplasmosis underwent resection of an atherosclerotic abdominal aortic aneurysm. Yeast forms of Histoplasma capsulatum were present in the aneurysm. Surgical resection and revascularization with a Dacron graft followed by systemic amphotericin B therapy and chronic ketoconazole suppressive therapy have resulted in a patient without symptoms 15 months postoperatively. It is important to be aware of the potential for artherosclerotic aortic aneurysm involvement by H. capsulatum.
D000368:Aged; D001012:Aorta, Abdominal; D001014:Aortic Aneurysm / Q000628:therapy*; D005260:Female; D006660:Histoplasmosis / Q000628:therapy*; D006801:Humans