Induction of non-IgE anaphylactic antibodies in dogs.
Dogs immunized with o-DNCP-BSA or eggs of Toxocara canis developed anaphylactic antibodies other than IgE. The antibodies were heat-resistant at 56 degrees C for 2 hours, not reduced by 2-mercaptoethanol and PCA and P-K reactivity was only observed at 3-4 h sensitized sites of recipient skin. High titres of antigen-specific IgGd were determined by means of an ELISA technique.
D000707:Anaphylaxis / Q000276:immunology*; D000818:Animals; D000917:Antibody Formation; D004140:Dinitrophenols / Q000276:immunology; D004285:Dogs; D004587:Electrophoresis, Agar Gel; D004804:Eosinophils; D005260:Female; D007122:Immunoelectrophoresis; D007073:Immunoglobulin E / Q000096:biosynthesis; D007074:Immunoglobulin G / Q000096:biosynthesis; D007428:Intradermal Tests; D007958:Leukocyte Count; D008297:Male; D010323:Passive Cutaneous Anaphylaxis; D014119:Toxocara / Q000276:immunology
D004140:Dinitrophenols; D007074:Immunoglobulin G; D007073:Immunoglobulin E