Nephrogenic adenoma in children.
Nephrogenic adenoma is a rare, benign lesion of the bladder, occurring as an epithelial response to infection or trauma. Characteristically, it presents as a papillary lesion resembling a low grade, low stage transitional cell carcinoma. Although usually occurring in adults, there have been 5 reports in children, in whom the adenoma occurred following either surgery or localized inflammation. We report on 2 additional children with nephrogenic adenoma, including one who presented with a bladder mass and total occlusion of the ipsilateral ureter, while in the other it was found incidentally during closure of a vesicovaginal fistula. Successful treatment consisted of transurethral resection and low dose suppressive antibiotics. Nephrogenic adenoma, while rare in children, appears to be a uroepithelial metaplastic response to trauma or inflammation and is treated best by conservative management.
D000236:Adenoma / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology