Lidocaine and prevention of ventricular fibrillation complicating acute myocardial infarction.
Prehospital prevention of primary ventricular fibrillation using 400 mg lidocaine i.m. may be effective in subjects aged under 70, but routine administration is not yet recommended since mortality was unaffected. Although in-hospital prevention of ventricular fibrillation can be achieved by routine i.v. administration of lidocaine in rather high dosages, this regimen is still controversial in well-equipped CCUs in view of conflicting results on mortality.
D000368:Aged; D003325:Coronary Care Units; D003422:Critical Care / Q000379:methods; D006801:Humans; D008012:Lidocaine / Q000627:therapeutic use*; D009203:Myocardial Infarction / Q000150:complications* / Q000401:mortality; D011379:Prognosis; D012008:Recurrence; D014693:Ventricular Fibrillation / Q000401:mortality / Q000517:prevention & control*
D008012:Lidocaine