Invasive squamous cell carcinoma of the carpus: malignant transformation of epidermis dysplasia verruciformis.
Epidermodysplasia verruciformis is a rare disease that is characterized by the eruption of wartlike skin lesions. There is a high incidence of malignant transformation of these lesions, especially in areas exposed to the sun, such as the face or the dorsum of the hands. We present a case that demonstrates many aspects of this disease entity, which ultimately required amputation of the hand because of invasive squamous cell carcinoma of the carpal bones.
D000671:Amputation, Surgical; D001859:Bone Neoplasms / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D002348:Carpal Bones / Q000601:surgery; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D006225:Hand / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology