title: An evaluation of a leukocyte esterase/nitrite test strip and a bioluminescence assay for detection of bacteriuria.
abstract: A leukocyte esterase/nitrite (Chemstrip LNTM) and a bioluminescence assay (LumacTM) were evaluated for detection of bacteriuria in 1,000 urine specimens. Both devices provided high predictive negative values (95.4-97.8%); however, false-negative values at levels of bacteriuria greater than or equal to 10(4) CFU/ml were 22.6% and 12.3%, respectively, for the leukocyte esterase/nitrate and the bioluminescence assay tests. The corresponding false-negative values at levels of bacteriuria of greater than or equal to 10(5) CFU/ml were 16.5% and 3.9%, respectively.
mesh_terms: D001437:Bacteriuria / Q000175:diagnosis*; D004950:Esterases / Q000097:blood; D005188:False Negative Reactions; D006801:Humans; D007202:Indicators and Reagents; D007962:Leukocytes / Q000201:enzymology; D008163:Luminescent Measurements; D009573:Nitrites / Q000378:metabolism; D011933:Reagent Kits, Diagnostic; D011934:Reagent Strips
chemical_list: D007202:Indicators and Reagents; D009573:Nitrites; D011933:Reagent Kits, Diagnostic; D011934:Reagent Strips; D004950:Esterases