Morphometry of mitochondrial changes in mouse trophoblast cells at early implantation.
The blastocysts of a mouse in an experimentally delayed implantation are known to have a low consumption of oxygen, but when implantation is initiated their oxygen consumption increases within 4 h. Our stereological analyses of the mitochondria have demonstrated that these changes are associated with an increase in volume density of the mitochondrial matrix and a decrease of surface density of the inner membranes. Thus, at this early stage of blastocyst implantation, the mitochondria of the activated blastocysts change to an orthodox state.
D000818:Animals; D001755:Blastocyst / Q000378:metabolism / Q000648:ultrastructure*; D010064:Embryo Implantation; D010065:Embryo Implantation, Delayed; D004967:Estrogens / Q000494:pharmacology; D005260:Female; D051379:Mice; D008854:Microscopy, Electron; D008928:Mitochondria / Q000378:metabolism / Q000648:ultrastructure*; D010085:Oxidative Phosphorylation; D010101:Oxygen Consumption; D014327:Trophoblasts / Q000378:metabolism / Q000648:ultrastructure*
D004967:Estrogens