[Morphological evidence of celiac ganglion hyperfunction in spontaneous hypertension in rats].
To elucidate the role of the autonomous nervous system in formation of a specific renal "resetting", typical for arterial hypertension, in 8-week-old spontaneously hypertensive rats, a study was made of the morphology of the celiac ganglion as one of the main sources of renal innervation. Light and fluorescent microscopy demonstrate the hypertrophy of the neurons and their nuclei, an increase in the whole ganglion volume and the volume density of the SIF cells. This evidence for hyperactivity of the celiac ganglion attests to the involvement of the renal nervous system in the structural and functional reorganization ("resetting") at the early stages of hypertension as well as a manifestation of hyperactivity of the nervous system in this disease.
D000818:Animals; D002838:Chromaffin System / Q000503:physiopathology; D005260:Female; D005728:Ganglia, Sympathetic / Q000503:physiopathology*; D006973:Hypertension / Q000503:physiopathology*; D009474:Neurons / Q000473:pathology; D051381:Rats; D011918:Rats, Inbred SHR; D011919:Rats, Inbred Strains
Morfologicheskie dokazatel'stva giperfunktsii chrevnogo gangliia pri spontannoĭ gipertenzii u krys.