Release of Fc-receptors after streptococcal lysis induced by a lytic enzyme from Streptomyces globisporus.
Streptomyces globisporus produced an enzyme which had lytic effects on streptococci and was able to solubilize their Fc-receptors. A new method for rapid purification of this enzyme was described. It consisted of adsorption to Amberlite CG 50 and subsequent chromatography on CM-cellulose Whatman CM 52. The purified enzyme was free of proteases and had lysed streptococci of serological groups A, B, C, G and L. It released Fc-receptors from the streptococcal surface in a biologically active form.
D004798:Enzymes / Q000302:isolation & purification; D011961:Receptors, Fc / Q000302:isolation & purification*; D012995:Solubility; D013291:Streptococcus / Q000378:metabolism*; D013302:Streptomyces / Q000201:enzymology*
D004798:Enzymes; D011961:Receptors, Fc