Antibody in tears, saliva and nasal secretions following oral immunization of humans with inactivated influenza virus vaccine.
Oral immunization of 5 volunteers with an enteric-coated inactivated influenza vaccine resulted in a significant rise of IgA-specific antibodies in tears, saliva and nasal secretion, reaching a maximum response 5-7 weeks after completion of immunization.
D000284:Administration, Oral; D000906:Antibodies / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007114:Immunization; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007252:Influenza Vaccines / Q000008:administration & dosage*; D009297:Nasal Mucosa / Q000276:immunology / Q000378:metabolism*; D012463:Saliva / Q000276:immunology*; D013666:Tears / Q000276:immunology*; D014613:Vaccines, Attenuated / Q000008:administration & dosage*
D000906:Antibodies; D007071:Immunoglobulin A, Secretory; D007252:Influenza Vaccines; D014613:Vaccines, Attenuated