Susceptibility of Candida species strains to five antifungal agents: comparison between agar dilution and disk diffusion tests.
The in vitro activity of five antifungal agents were compared against 180 Candida strains. The drugs were: two imidazoles (miconazole and ketoconazole), nystatin, 5-fluorocytosine and amphotericin B. Agar dilution and disk diffusion methods were used. Nystatin, miconazole and amphotericin B were the most active agents. 5-fluorocytosine had high activity except against C. albicans serotype B, of which a high percentage were resistant. Finally, a good correlation between the two methods was observed.
D000362:Agar; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D003470:Culture Media; D004058:Diffusion; D008826:Microbial Sensitivity Tests
D000935:Antifungal Agents; D003470:Culture Media; D000362:Agar