Trisomy 7 in a lung carcinoid tumor: precocious index of malignant transformation?
A chromosomal study has been performed on a benign carcinoid tumor of the lung after short-term culture. A trisomy of chromosome #7 was found in all the metaphases. The significance of this finding is discussed in relation to the transformation process.
D002276:Carcinoid Tumor / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D006801:Humans; D007621:Karyotyping; D008175:Lung Neoplasms / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000235:genetics; D014314:Trisomy