title: [Study of sodium metabolism in the bodies of patients with essential hypertension by the profile scanning technic using 22Na].
abstract: Profile scanning with sodium-22 nuclide was performed in 37 patients with essential hypertension to determine the time-course of the isotope distribution in different parts of the body and the rate of its elimination. The rate of sodium-22 infiltration into the tissues of the pelvis and lower extremities was higher in women than in men, and that of elimination lower than in men with a stable course of arterial hypertension. This index showed no correlation with changes of the central hemodynamics and glomerular filtration. The labile and stable courses of arterial hypertension were characterized by different rates of sodium-22 uptake by the renal tissue.
mesh_terms: D000328:Adult; D005260:Female; D005919:Glomerular Filtration Rate; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000378:metabolism*; D007866:Leg / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010388:Pelvis / Q000378:metabolism; D011877:Radionuclide Imaging; D012737:Sex Factors; D012964:Sodium / Q000378:metabolism*; D012979:Sodium Radioisotopes; D014018:Tissue Distribution
chemical_list: D012979:Sodium Radioisotopes; D012964:Sodium
vernacular_title: Izuchenie obmena natriia v organizme bol'nykh gipertonicheskoĭ bolezn'iu metodom profil'nogo skennirovaniia s nuklidom 22Na.