[Effect of enkephalins on the calcium-regulating function of the endocrine glands].
Experiments on rats have shown that administration of a synthetic analog of leuenkephalin at a dose of 100 mg/kg did not change the content of the immunoreactive parathyroid hormone in the blood plasma but removed the parathyroidin stimulating effect on the cAMP concentration in the renal tissue and AP activity in the blood. It is concluded that enkephalins do not influence the secretion and metabolism of the parathyroid hormone but block its peripheral effects and stimulate thyroid C-cell function.
D000818:Animals; D002116:Calcitonin / Q000502:physiology*; D002118:Calcium / Q000378:metabolism*; D004743:Enkephalin, Leucine / Q000008:administration & dosage / Q000494:pharmacology*; D007274:Injections, Intraperitoneal; D008297:Male; D010280:Parathyroid Glands / Q000378:metabolism*; D010281:Parathyroid Hormone / Q000502:physiology*; D051381:Rats; D013268:Stimulation, Chemical; D013961:Thyroid Gland / Q000378:metabolism*; D013997:Time Factors
D010281:Parathyroid Hormone; D004743:Enkephalin, Leucine; D002116:Calcitonin; D002118:Calcium
Vliianie enkefalinov na funktsiiu kal'tsiĭreguliruiushchikh endokrinnykh zhelez.