[The in vitro liberation behavior of quinidine from drug forms with prolonged release by various liberation methods].
The liberation behaviour of the following preparations were tested using two models: Chinidin-Duriles (Astra, Sweden), Chinidin-longo (VEB Isis-Chemie Zwickau, GDR), Chinidin-retard-Isis (VEB Isis-Chemie Zwickau, GDR). The received data were estimated by multivariate statistical methods. It was found, that the three tested preparations are different in their liberation behaviour. Moreover it was shown, that there are differences between the two apparatus. Nevertheless both methods are able to characterize the liberation behaviour of the three preparations.
D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations; D011802:Quinidine / Q000008:administration & dosage* / Q000032:analysis; D013997:Time Factors
D003692:Delayed-Action Preparations; D011802:Quinidine
Untersuchungen zum in-vitro-Freisetzungsverhalten von Chinidin aus Arzneiformen mit verlängerter Wirksamkeit anhand verschiedener Liberationsmodelle.