Effect of naloxone on arterial gases in chronically obstructed patients with acute respiratory failure.
In a randomized double-blind design 10 patients with decompensated COPD received intravenous naloxone (2 mg) and placebo. Arterial gases were monitored at 15, 30 and 60 min. No significant changes were observed in pCO2 after naloxone as compared to placebo.
D001784:Blood Gas Analysis; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000150:complications* / Q000188:drug therapy; D009270:Naloxone / Q000494:pharmacology / Q000627:therapeutic use*; D012119:Respiration / Q000187:drug effects; D012131:Respiratory Insufficiency / Q000209:etiology*
D009270:Naloxone