Short term effect of a low fat diet on plasma retinol and alpha-tocopherol and red cell alpha-tocopherol levels in hyperlipidemic men.
The effect of a low fat, low cholesterol diet on plasma alpha-tocopherol and retinol and erythrocyte alpha-tocopherol levels was studied in fourteen hyperlipidemic men for a period of 28 days. Plasma alpha-tocopherol decreased with decreasing plasma cholesterol levels while the ratio of plasma alpha-tocopherol to cholesterol remained constant. There was a tendency for plasma retinol levels to decrease but the change was not significant. As plasma alpha-tocopherol levels decreased there was a consistent and significant increase in alpha-tocopherol content of red cells (p less than 0.001). These findings indicate that fat soluble vitamin status is maintained with low fat diets during a short time period.
D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D004041:Dietary Fats / Q000008:administration & dosage*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000178:diet therapy*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
D008076:Cholesterol, HDL; D004041:Dietary Fats; D014280:Triglycerides; D014801:Vitamin A; D014810:Vitamin E; D002784:Cholesterol