title: Phosphorylation of 3-O-methyl-D-glucose by yeast and beef hexokinase.
abstract: Beef heart hexokinase and yeast hexokinase both catalyzed the phosphorylation of 3-O-[14C]methyl-D-glucose. The maximal velocity was 3 orders of magnitude lower and the Km for the glucose analogue 40-120-times higher than those observed with D-[U-14C]glucose. Hence, 3-O-methyl-D-glucose should not be considered as a truly nonmetabolized analogue of D-glucose.
mesh_terms: D019325:3-O-Methylglucose; D000818:Animals; D002250:Carbon Radioisotopes; D002417:Cattle; D005947:Glucose / Q000378:metabolism; D006593:Hexokinase / Q000494:pharmacology*; D007700:Kinetics; D008757:Methylglucosides / Q000378:metabolism*; D008759:Methylglycosides / Q000378:metabolism*; D010766:Phosphorylation; D015003:Yeasts / Q000201:enzymology
chemical_list: D002250:Carbon Radioisotopes; D008757:Methylglucosides; D008759:Methylglycosides; D019325:3-O-Methylglucose; D006593:Hexokinase; D005947:Glucose