Pyrolysis products of heroin.
Heating of heroin hydrochloride or of heroin at 250 degrees C led to extensive degradation. Major components of the pyrolysate were identified as heroin, 6-acetylmorphine, N,6-diacetylnormorphine, and N-acetylnorheroin by comparison of mass spectra and 13C- and 1H-nuclear magnetic resonance (NMR) spectra with those of authentic compounds. There was evidence for degradation of the piperidino moiety and the structure 3,4-diacetoxyphenanthrene was proposed for a minor product.
D055598:Chemical Phenomena; D002621:Chemistry; D003932:Heroin / Q000031:analogs & derivatives / Q000032:analysis*; D006358:Hot Temperature; D009022:Morphine Derivatives / Q000032:analysis
D009022:Morphine Derivatives; C044765:N,6-diacetylnormorphine; C044764:N-acetylnorheroin; D003932:Heroin; C026979:6-O-monoacetylmorphine