title: A practical, high-resolution, microcomputer-based method for the analysis of relaxation data exhibiting multicomponent exponential decays.
abstract: We have developed and tested a practical, rapid, high-resolution, microcomputer-based method for the analysis of multicomponent exponential decays. The analysis utilizes the Fourier deconvolution technique and includes methods to reduce noise both in the input data and in the results. The developed method is particularly well suited for analysing decays consisting of a wide range of decay times. The method resolves two exponential decays differing by a factor of two when the input data are mathematically generated and without noise, and resolves two decays differing by a factor of three when 2% Gaussian noise is present in the same data. The method lends itself to routine analysis of any relaxation process consisting of exponential decays, including biomedical applications such as enzyme kinetics, circulatory transport functions, pharmacokinetics, plasma exchange therapy, and analysis of compartmental models for any process.
mesh_terms: D001718:Birefringence; D003201:Computers; D046911:Macromolecular Substances; D008838:Microcomputers; D012996:Solutions
chemical_list: D046911:Macromolecular Substances; D012996:Solutions