Clear cell myeloma.
We report a case of clear cell myeloma misinterpreted at initial biopsy as liposarcoma. The patient had lytic skeletal lesions and monoclonal IgA, kappa, serum immunoglobulin. The tumor cells contained cytoplasmic vacuoles that produced a clear histologic appearance. The light-microscopic and ultrastructural findings are compared with those of other cases of lymphoplasmacytic disorders with prominent cytoplasmic inclusions.
D000368:Aged; D001706:Biopsy; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D002968:Clavicle; D003937:Diagnosis, Differential; D006801:Humans; D008080:Liposarcoma / Q000175:diagnosis; D008297:Male; D009101:Multiple Myeloma / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D014617:Vacuoles