Familial combined hyperlipidemia and otosclerosis--the occurrence in a large kindred.
The occurrence of otosclerosis and hyperlipidemia in four generations of a single family is described. The lipid abnormality fulfilled the characteristics of combined familial hyperlipidemia. Whereas a genetic linkage between combined hyperlipidemia and otosclerosis is feasible, our study indicates that both conditions are inherited through autosomal but unlinked genes.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D006950:Hyperlipidemia, Familial Combined / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000235:genetics; D010040:Otosclerosis / Q000150:complications / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype