title: [Capillarosclerosis of the efferent urinary tract as an indication of analgesic abuse. Incidence in unselected autopsies in a large West German town].
abstract: In a prospective study conducted during one year, postmortem examination of 500 unselected adults revealed in 13 cases (2.6%) a marked capillarosclerosis of the mucosa of the renal pelvis, considered to be a reliable histological sign of phenacetin and paracetamol abuse. These results were obtained in four men (1.5% of the total number of autopsied men) and nine women (3.9% of the autopsied women). Thus, capillarosclerosis is 2.6 time more frequent in women than in men.
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects; D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000139:chemically induced*; D001344:Autopsy; D002196:Capillaries; D005260:Female; D006801:Humans; D007682:Kidney Pelvis; D008297:Male; D008875:Middle Aged; D010615:Phenacetin / Q000009:adverse effects; D019966:Substance-Related Disorders / Q000150:complications*
chemical_list: D000082:Acetaminophen; D010615:Phenacetin
vernacular_title: Kapillarosklerose der ableitenden Harnwege als Indiz eines Analgetika-Abusus. Häufigkeit bei unausgewählten Obduktionen in einer westdeutschen Grossstadt.