Progressive varicella in three patients with Wiskott-Aldrich syndrome: treatment with adenine arabinoside.
Patients with Wiskott-Aldrich Syndrome have an increased incidence of serious infections, often with microorganisms that usually produce mild disease in immunologically normal subjects. Three patients with Wiskott-Aldrich syndrome complicated by progressive varicella are reported. There have been no previous reports of similar cases. Two of the patients were treated with adenine arabinoside and had rapid recovery.
D000293:Adolescent; D000914:Antibodies, Viral / Q000032:analysis; D002644:Chickenpox / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology / Q000517:prevention & control; D002648:Child; D006801:Humans; D007106:Immune Sera / Q000008:administration & dosage; D007116:Immunization, Passive; D007223:Infant; D008297:Male; D014740:Vidarabine / Q000627:therapeutic use*; D014923:Wiskott-Aldrich Syndrome / Q000150:complications*
D000914:Antibodies, Viral; D007106:Immune Sera; C030799:varicella-zoster immune globulin; D014740:Vidarabine