title: Chronic lymphocytic leukemia presenting as an anal mass.
abstract: A middle-aged man sought medical attention because of a large perianal mass. The lesion was caused by a massive subepithelial infiltrate of small neoplastic lymphocytes representing a localized tissue manifestation of chronic lymphocytic leukemia. This report emphasizes the possibility of leukemia/lymphomas occurring at the anus, to stress that leukemia should be considered in the differential diagnosis of patients presenting with perianal disease in the presence of lymphadenopathy and constitutional symptoms.
mesh_terms: D001003:Anal Canal / Q000473:pathology; D001005:Anus Neoplasms / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007945:Leukemia, Lymphoid / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged