title: [Cerebrospinal fluid and multiple sclerosis].
abstract: A survey of the relevant diagnostic methods in the cerebrospinal fluid in multiple sclerosis is given. In over 90% positive results are obtained, showing the inflammatory CNS-process or myelin break down. Personal findings demonstrate the relevance of lymphocytic transformation in CNS inflammatory diseases. In 73% of definitive MS cases transformed lymphocytes occurred, commonly associated with a pathological IgG/Albumin ratio, but in 23% of chronic progressive cases in isolation. Under unselected cerebrospinal fluids with transformed lymphocytes and a cell count under 16 per micro 1 multiple sclerosis was suspected clinically in 70%, in further 20% other inflammatory diseases were present while only 10% unspecific cases occurred.
mesh_terms: D002555:Cerebrospinal Fluid / Q000166:cytology; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid* / Q000276:immunology; D012709:Serum Albumin / Q000134:cerebrospinal fluid
chemical_list: D002556:Cerebrospinal Fluid Proteins; D007074:Immunoglobulin G; D012709:Serum Albumin
vernacular_title: Liquor cerebrospinalis und Multiple Sklerose.