[The pattern of regional disorders of wall motion in primary dilated cardiomyopathy].
Regional left ventricular wall motion was measured in 41 patients with dilated cardiomyopathy (DCM) and 30 healthy normal controls. Global and regional left ventricular function was noninvasively determined by radionuclide angiography (RNA). The amplitudes and phases of the first Fourier coefficient of the regional time-activity curves were used to measure regional wall motion. The normal left ventricle has its strongest contractions in the apical and distal antero-septal regions. In contrast, the left ventricle of patients with DCM contracts the least in these segments. These regional wall motion impairments are parallel to the reduced global left ventricular function. Since such a typical pattern of reduced wall motion can already be demonstrated in patients with mild DCM, determination of regional left ventricular wall motion can help to improve the early detection of DCM.
D002302:Cardiac Output; D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging*; D004912:Erythrocytes; D005260:Female; D006346:Heart Septum / Q000000981:diagnostic imaging; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D011877:Radionuclide Imaging; D013667:Technetium
D013667:Technetium
Muster der regionalen Wandbewegungsstörung bei primärer dilatativer Kardiomyopathie.