title: Multicompartment kinetic model for lead. III. Lead in blood plasma and erythrocytes.
abstract: Multicompartment models have been fitted to experimental data on plasma lead and blood lead concentrations of subjects studied by P. E. deSilva (Brit. J. Ind. Med. 38, 209-217, 1981) and one subject studied by W.I. Manton and C.R. Malloy (Brit. J. Ind. Med. 40, 51-57, 1983). Nonlinear models for plasma lead vs blood lead in populations provide significantly better descriptions than does a linear model. Short-term kinetic data do not clearly resolve the precise nonlinear mechanism, however, Parameters of plasma and erythrocyte distribution in a single subject were significantly different on two occasions.
mesh_terms: D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D007854:Lead / Q000097:blood*; D008297:Male; D008875:Middle Aged; D008954:Models, Biological
chemical_list: D007854:Lead