title: Ectopic prolactinoma in a patient with hyperparathyroidism and abnormal sellar radiography.
abstract: In a patient with hyperparathyroidism and chronic renal failure due to polycystic kidney disease, a finding of destroyed sellar and parasellar structures and hyperprolactinemia suggested the diagnosis of invasive pituitary prolactinoma. At surgery no tumor was found, and pathological examination of the sphenoid bone revealed a parathyroid bone lesion (brown tumor) as well as ectopic prolactinoma in the clivus. This patient demonstrates that a tumor may develop in ectopic pituitary tissue. The combination of radiographically abnormal sellar structures with pituitary hormone hypersecretion should not be regarded as absolute proof of a pituitary adenoma.
mesh_terms: D002828:Choristoma / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D003388:Cranial Fossa, Posterior; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D006966:Hyperprolactinemia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010902:Pituitary Gland / Q000378:metabolism*; D011388:Prolactin / Q000378:metabolism*; D011859:Radiography; D012658:Sella Turcica / Q000000981:diagnostic imaging*; D012888:Skull Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology
chemical_list: D011388:Prolactin