title: Performance of five thyroid-function tests by radioimmunoassays with antibodies attached to paramagnetic micro-particles.
abstract: We have assessed the analytical and clinical performance of five thyroid-function tests by commercially available radioimmunoassays in which antibodies attached to paramagnetic micro-particles are used (Corning MAGIC assays). We evaluated the methods for measuring thyroxin, triiodothyronine, triiodothyronine uptake, thyrotropin (thyroid-stimulating hormone), and free thyroxin. Precision, patients' results, and clinical correlation of the MAGIC assays were similar to those of the well-established RIAs used as the comparative methods in this study; the MAGIC assays, however, are much faster and easier to perform.
mesh_terms: D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood; D007037:Hypothyroidism / Q000097:blood; D008280:Magnetics; D008863:Microspheres; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011863:Radioimmunoassay / Q000379:methods; D012016:Reference Values; D013960:Thyroid Function Tests / Q000379:methods*; D013963:Thyroid Hormones / Q000097:blood*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D013963:Thyroid Hormones; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine