title: Effect of refrigerated storage on cefaclor in Mueller-Hinton agar.
abstract: Cefaclor is less stable than most cephalosporins in media at 35 degrees C. We demonstrated that the activity of cefaclor in Mueller-Hinton agar diminishes continuously at 4 degrees C, resulting in a loss of two-thirds of the activity within 21 days. We recommend that agar dilution plates for this cephalosporin be prepared on the day of their use.
mesh_terms: D001419:Bacteria / Q000187:drug effects; D002433:Cefaclor / Q000494:pharmacology; D002435:Cefamandole / Q000494:pharmacology; D002506:Cephalexin / Q000031:analogs & derivatives; D003470:Culture Media; D004355:Drug Stability; D012034:Refrigeration
chemical_list: D003470:Culture Media; D002435:Cefamandole; D002433:Cefaclor; D002506:Cephalexin