title: Physiologic closure of a symptomatic patent foramen ovale with oxygen therapy.
abstract: Surgery is required for correction of a physiologically significant patent foramen ovale. We report a patient with poliomyelitis and respiratory failure in whom a patent foramen ovale became symptomatic because of hypoxemia-induced pulmonary hypertension. Oxygen therapy and mechanical ventilation reversed the pulmonary hypertension, resulting in physiologic termination of the patent foramen ovale without surgery.
mesh_terms: D000368:Aged; D006344:Heart Septal Defects, Atrial / Q000188:drug therapy*; D006801:Humans; D006935:Hypercapnia / Q000209:etiology; D006976:Hypertension, Pulmonary / Q000209:etiology; D000860:Hypoxia / Q000150:complications / Q000209:etiology; D008297:Male; D010100:Oxygen / Q000627:therapeutic use*; D011051:Poliomyelitis / Q000150:complications; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000150:complications / Q000209:etiology
chemical_list: D010100:Oxygen