title: Necrotizing fasciitis in contused areas.
abstract: Four patients are presented who sustained blunt trauma and later developed necrotizing fasciitis in the areas of contusion, associated with the distant locus of sepsis. Three of the cases developed acute renal failure and later died. Early recognition of this condition allows prompt debridement beyond the margins of involved necrotic fascia, followed by wound inspection 8-hourly, and treatment with antibiotics, most recently third-generation cephalosporins, piperacillin, amikacin, and vancomycin.
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001134:Arm Injuries / Q000150:complications*; D001424:Bacterial Infections / Q000150:complications / Q000628:therapy; D003288:Contusions / Q000150:complications*; D003646:Debridement; D005208:Fasciitis / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009336:Necrosis; D014946:Wound Infection / Q000150:complications / Q000628:therapy; D014949:Wounds, Nonpenetrating / Q000150:complications*
chemical_list: D000900:Anti-Bacterial Agents