[Changes in the indices of carbohydrate metabolism, of the lipoprotein spectrum and of the blood coagulation system in men with ischemic heart disease undergoing long-term propranolol treatment].
The paper is concerned with evidence of the time course of blood sugar, lipoprotein spectrum and some values of the blood coagulation system in patients with CHD on prolonged propranolol therapy in comparison with their natural time course in a similar group of patients with CHD receiving no therapy. Propranolol therapy for 2 yrs. produced no changes in the lipoprotein spectrum and blood fibrinogen. The level of blood sugar on an empty stomach rose 6 and 12 mos after treatment and did not differ from the control one in 24 mos, and the coagulation index significantly exceeded the control one in 24 mos. The results obtained are suggestive of a necessity of control over the level of blood sugar and hemocoagulation during a prolonged and continuous intake of propranolol.
D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects*; D001786:Blood Glucose / Q000032:analysis*; D003327:Coronary Disease / Q000097:blood / Q000188:drug therapy*; D004341:Drug Evaluation; D005215:Fasting; D005951:Glucose Tolerance Test; D006801:Humans; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011433:Propranolol / Q000627:therapeutic use*; D013997:Time Factors
D001786:Blood Glucose; D008055:Lipids; D008074:Lipoproteins; D011433:Propranolol
Izmenenie nekotorykh pokazateleĭ uglevodnogo obmena, spektra lipoproteidov i sistemy svertyvaniia krovi u muzhchin s ishemicheskoĭ bolezn'iu serdtsa pri dlitel'nom lechenii propranololom.