title: Naproxen-induced pseudoporphyria. A clinical and ultrastructural study.
abstract: Pseudoporphyria is a condition clinically and ultrastructurally identical to porphyria cutanea tarda but with no associated abnormality of heme synthesis. A 45-year-old woman with bullae on the dorsa of her hands was found on investigation to have pseudoporphyria. Her symptoms remitted following the cessation of naproxen therapy.
mesh_terms: D000818:Animals; D001706:Biopsy; D003937:Diagnosis, Differential; D004820:Epidermolysis Bullosa / Q000473:pathology; D005260:Female; D006225:Hand; D006801:Humans; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D008875:Middle Aged; D009288:Naproxen / Q000009:adverse effects*; D011164:Porphyrias / Q000139:chemically induced* / Q000473:pathology; D011166:Porphyrins / Q000097:blood / Q000652:urine; D012756:Sheep; D012867:Skin / Q000098:blood supply / Q000473:pathology
chemical_list: D011166:Porphyrins; D009288:Naproxen