Computerized tomographic scan changes in early schizophrenia--preliminary findings.
Thirty patients who fulfilled DSM-III criteria for schizophrenia but who were within 2 years of presentation were compared with 26 age-matched normal volunteers with respect to CT scan appearances. In the index group the ventricle-brain ratio (VBR) was significantly greater. The VBR values were positively correlated with average alcohol intake and with early physical trauma, and negatively correlated with a family history of schizophrenia. The implications of these findings are discussed in the context of the present uncertainty about the meaning of CT scan findings in schizophrenia.
D000328:Adult; D001921:Brain / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000473:pathology*; D014057:Tomography, X-Ray Computed