Analysis of treatment results in craniopharyngioma.
A retrospective study of 30 patients treated primarily with surgery for craniopharyngioma between 1965 and 1980 was conducted. There were 13 children and 17 adults in this series. Apparent total surgical removal was obtained in six children and eight adults; the remaining patients had subtotal resection. Radiation therapy was used for salvage in five patients and after complete cyst removal in one. The ten-year survival rate was 80% in children and 30% in adults. The five-year survival was ten of 11 patients with childhood craniopharyngioma and seven (41%) of 17 patients in the adult group. Seven of 13 patients in the childhood group experienced surgically documented recurrence after first surgery. Seven of 17 patients recurred after first surgery in the adult group. Four died of operative complications. Morbidity demonstrated by quality of survival was high in these patients.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003397:Craniopharyngioma / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007016:Hypophysectomy / Q000379:methods; D007223:Infant; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010911:Pituitary Neoplasms / Q000473:pathology / Q000601:surgery*; D011788:Quality of Life; D012189:Retrospective Studies