title: Decompression sickness and intravenous bubble formation using a 7.8 psia simulated pressure-suit environment.
abstract: The purpose of this study was to determine the minimum spacesuit pressure required to prevent decompression sickness (DCS) during operational conditions in a 50% oxygen/50% nitrogen environment. In this study, 30 male volunteer subjects were exposed in groups of three, to three consecutive daily extravehicular activity (EVA) simulations at 7.8 psia (5,031 m altitude equivalent) for a continuous period of 6 h. During each altitude exposure, the subjects participated in similar exercise workloads expected to be experienced by astronauts during a typical EVA scenario. Precordial Doppler monitoring revealed that 73.3% of the subjects had intravenous bubbling during at least 1 d of the 3 d of exposure, with 26.7% remaining bubble-free during the entire study. No correlation was found between either body fat or age and incidence of bubble formation. One case of DCS occurred during the study indicating that 7.8 psia is not sufficient pressure to totally preclude DCS in a 50% oxygen/50% nitrogen environment. The necessary pressure awaits further study.
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D003665:Decompression Sickness / Q000517:prevention & control*; D005118:Extraterrestrial Environment; D005676:Gravity Suits; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood; D011312:Pressure; D013026:Space Flight; D014465:Ultrasonics
chemical_list: D010100:Oxygen