Dystonia and calcification of the basal ganglia.
We studied a family with dominantly inherited dystonia and intracranial calcification. Thirty-seven members were examined; 13 were affected by dystonia that was segmental in most patients, affecting especially the voice, face, neck, and limbs. Intracranial calcification involved the putamen, pallidum, cerebral white matter and cortex, and cerebellar nuclei. Several patients had both dystonia and calcification, but others had either dystonia or calcification alone.
D000328:Adult; D001480:Basal Ganglia Diseases / Q000000981:diagnostic imaging* / Q000235:genetics; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000235:genetics; D004421:Dystonia / Q000000981:diagnostic imaging* / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed