Hypothalamic hamartoma: report of two cases.
Two histologically confirmed hypothalamic hamartomas, one in a 7-year-old boy and another in a 10-year-old boy, are reported. One patient had precocious puberty, epileptic laughter, and abnormal behavior; the other had cerebral seizures. Partial removal of the tumors had no effect on precocious puberty; however, behavior improved in the first patient, and seizure control improved in the second patient.
D002648:Child; D004827:Epilepsy / Q000209:etiology; D006222:Hamartoma / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007029:Hypothalamic Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D007845:Laughter; D008297:Male; D011629:Puberty, Precocious / Q000209:etiology; D011859:Radiography; D012640:Seizures / Q000209:etiology