Penetration of timolol eye drops into human aqueous humour: the first hour.
Samples of aqueous humour were removed from 26 eyes at the start of cataract extraction. Two drops of timolol 0.5% had been instilled into the conjunctival sac 12-71 minutes before operation. Analysis by gas chromatography showed a mean timolol concentration of 55.46 ng/mg, with a range of 8 to 100 ng/mg.
D001082:Aqueous Humor / Q000378:metabolism*; D002387:Cataract Extraction; D006801:Humans; D013997:Time Factors; D013999:Timolol / Q000378:metabolism*
D013999:Timolol