title: Onyalai in pregnancy--effects on the mother and the newborn.
abstract: Eight pregnant Kavango women with documented active onyalai during pregnancy or a history of previous attacks of onyalai gave birth to 8 healthy infants who had no clinical signs of a tendency to haemorrhage and had normal platelet counts. Postpartum haemorrhage occurred in 2 patients. A splenectomy was successfully performed on the 7th day after delivery in 1 patient to control postpartum haemorrhage, and 3 months after confinement in another patient to control haemorrhage from another clinical attack of onyalai. Corticosteroids are not indicated in the management of onyalai. Infants of mothers with onyalai, unlike infants of mothers with idiopathic thrombocytopenic purpura, do not appear to be at risk of thrombocytopenia and haemorrhage.
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D010976:Platelet Count; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood; D013921:Thrombocytopenia / Q000097:blood