Carcinoma of the gallbladder: autopsy findings in 287 cases and review of the literature.
From 1950 to 1982, 287 patients with cancer of the gallbladder were autopsied. The ratio of men to women was 1:3.7. The average age of women was 70 years; that of men was 69.5 years. Most tumors (67.7%) had grown by diffuse infiltration and one-third (32.3%) were polypous-exophytic. Fundus and collum of the gallbladder showed an equal frequency (24%) of tumor localisation. The percentage of all gallbladder malignomas that were adenocarcinomas of various differentiation was 84.6, and 10.9% were anaplastic carcinomas, the rest consisted of squamous cell carcinomas (3.7%) and 0.8% sarcomas. Metastases were found in 265 cases (92.3%). Tumorous infiltration, lymph node metastases, and visceral metastases are discussed. A cholelithiasis was found in 78.4%. The results are compared with the literature.
D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D001344:Autopsy; D002277:Carcinoma / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002769:Cholelithiasis / Q000150:complications; D005260:Female; D005706:Gallbladder Neoplasms / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011379:Prognosis; D012509:Sarcoma / Q000473:pathology