Portal hypertension after successful hepatic portoenterostomy in biliary atresia.
From 1953 through 1984, we have operated on 225 cases of biliary atresia, and 95 patients are presently surviving. Portal hypertension with esophageal varices was endoscopically confirmed in 26 of 66 patients (39%) examined, 14 with and 52 without jaundice. All these patients except two had had frequent episodes of postoperative cholangitis. Eight patients have undergone treatment for portal hypertension. The treatment for variceal bleeding in jaundice-free infants with biliary atresia should be initiated conservatively, including endoscopic sclerotherapy. The results of our experience, however, justifies the employment of shunt procedures for patients older than 6 or 7 years of age.
D000293:Adolescent; D000328:Adult; D001652:Bile Ducts / Q000002:abnormalities*; D002648:Child; D002675:Child, Preschool; D002761:Cholangitis / Q000209:etiology; D004932:Esophageal and Gastric Varices / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology* / Q000628:therapy; D007223:Infant; D007583:Jejunum / Q000601:surgery; D008297:Male; D011183:Postoperative Complications / Q000209:etiology* / Q000628:therapy; D012597:Sclerosing Solutions / Q000627:therapeutic use
D012597:Sclerosing Solutions