[Treatment of arterial hypertension with calcium antagonists].
The antihypertensive effect of finoptin (verapamil) and corinfar (nifedipin) and their impact on the hemodynamics and the repolarization complex of the ECG were studied in 52 patients with essential hypertension and 48 patients with secondary arterial hypertension. The calcium antagonists were found to effectively decrease the blood pressure by reducing the peripheral resistance. Verapamil may be recommended for the monotherapy of mild and moderate forms of arterial hypertension, whereas corinfar should be used in cases of marked hypertension and at the third stage of therapy. Patients with electrocardiographic signs of myocardial ischemia show the normalization of the ST segment and a decreased depression of T wave under the impact of corinfar.
D001810:Blood Volume; D002302:Cardiac Output; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D009543:Nifedipine / Q000627:therapeutic use*; D014655:Vascular Resistance; D014700:Verapamil / Q000627:therapeutic use*
D014700:Verapamil; D009543:Nifedipine
Lechenie bol'nykh s arterial'noĭ gipertenzieĭ antagonistami kal'tsiia.