[Quantitative assessments of synergism].
The basic approaches to the assessment of the biological effects of combinations of different agents are briefly discussed. The situations of additivity, synergism and antagonism are defined with hetero- and isoaddition being taken into consideration. The practical application of the methods is illustrated by the analysis of the experimental data on the staphylococcus survival after the combined effect of gamma-irradiation and hydrogen peroxide or incubation at elevated temperature.
D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D006358:Hot Temperature; D006861:Hydrogen Peroxide / Q000494:pharmacology; D004364:Pharmaceutical Preparations; D011830:Radiation Effects; D013211:Staphylococcus aureus / Q000187:drug effects / Q000528:radiation effects
D003037:Cobalt Radioisotopes; D004364:Pharmaceutical Preparations; D006861:Hydrogen Peroxide
Kolichestvennye otsenki sinergizma.