[Specificity of the action of piracetam, encephabol and Cleregil on the transcallosal evoked potential].
The influence of some drugs having nootropic effect on transcallosal evoked potential was studied in the experiments on non-anesthetized rabbits. Pyracetam, pyritinol and cleregil have been established to increase the amplitude of transcallosal evoked potential. Each of these drugs was found to exert specific effects on this neurophysiological phenomenon. The authors suggest that transcallosal evoked potential can prove helpful in the detection of new drugs with possible nootropic effect.
D000818:Animals; D003337:Corpus Callosum / Q000187:drug effects*; D003642:Deanol; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations / Q000494:pharmacology; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D005971:Glutamates / Q000494:pharmacology*; D010889:Piracetam / Q000494:pharmacology*; D011619:Psychotropic Drugs / Q000494:pharmacology*; D011725:Pyridines / Q000494:pharmacology*; D011746:Pyrithioxin / Q000494:pharmacology*; D011760:Pyrrolidinones / Q000494:pharmacology*; D011817:Rabbits; D011930:Reaction Time / Q000187:drug effects
D004338:Drug Combinations; D005971:Glutamates; D011619:Psychotropic Drugs; D011725:Pyridines; D011760:Pyrrolidinones; D003642:Deanol; C043253:deanol aceglutamate; D011746:Pyrithioxin; D010889:Piracetam
Spetsifichnost' deĭstviia piratsetama, éntsefabola i kleregila na transkallozal'nyĭ vyzvannyĭ potentsial.