[Fatty acid composition of mitochondrial phospholipids of the ischemic heart].
Gas liquid chromatography was used to study fatty acid (FA) composition of lysophosphatidylcholine (lyso-PC) and phosphatidylcholine in isolated rabbit heart mitochondria. In control, lyso-PC and PC were found to contain 95 and 66% of unsaturated FA, respectively. At 1 hour of ischemia (autolysis at 37 degrees C) the percentage of saturated FA in lyso-PC noticeably increased whereas FA composition remained unchanged. It is concluded that changes in FA composition of lyso-PC are caused by phospholipase A2 action.
D000818:Animals; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D003327:Coronary Disease / Q000378:metabolism*; D005227:Fatty Acids / Q000032:analysis*; D008244:Lysophosphatidylcholines / Q000032:analysis; D008929:Mitochondria, Heart / Q000032:analysis*; D010713:Phosphatidylcholines / Q000032:analysis; D010743:Phospholipids / Q000032:analysis*; D011817:Rabbits
D005227:Fatty Acids; D008244:Lysophosphatidylcholines; D010713:Phosphatidylcholines; D010743:Phospholipids
Zhirnokislotnyĭ sostav fosfolipidov mitokhondriĭ ishemizirovannogo serdtsa.