title: A novel structural transition in poly(dG-Me5dC):Z in equilibrium B in equilibrium Z.
abstract: Poly(dG-Me5dC) is known to exhibit a B----Z transition in the presence of very high concentrations of NaCl. For the first time, we report the presence of a Z-structure in sodium concentrations as low as 0.5 mM. A novel Z in equilibrium B in equilibrium Z transition is observed as the salt concentration is gradually increased. The role of water structure in B to Z transitions is discussed.
mesh_terms: D002942:Circular Dichroism; D009690:Nucleic Acid Conformation; D009994:Osmolar Concentration; D011089:Polydeoxyribonucleotides; D012965:Sodium Chloride / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet
chemical_list: D011089:Polydeoxyribonucleotides; D012965:Sodium Chloride; C029988:poly(dG-m(5)dC).poly(dG-m(5)dC)