Absolute ethanol injection of the adrenal artery: hypertensive reaction.
Transcatheter injection of 0.4 ml of absolute ethanol into the adrenal artery was performed in three Rhesus monkeys. The injection produced a mean increase of 60 mmHg in systolic blood pressure and 50 mmHg in diastolic blood pressure within two minutes. Hypertension was accompanied by cardiac arrhythmias (two monkeys) and sinus tachycardia (one monkey). These changes were probably related to an acute catecholamine release. Embolization of the inferior phrenic artery with Gelfoam powder produced only a mild blood pressure elevation in three monkeys (6 mmHg systolic pressure and 10 mmHg diastolic pressure).
D000311:Adrenal Glands / Q000098:blood supply*; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000139:chemically induced; D001158:Arteries; D002404:Catheterization; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D000431:Ethanol / Q000008:administration & dosage / Q000633:toxicity*; D005781:Gelatin Sponge, Absorbable; D006973:Hypertension / Q000139:chemically induced*; D007269:Injections, Intra-Arterial; D008253:Macaca mulatta
D000431:Ethanol