title: Comparative study on mucus glycoproteins in rat stomach and duodenum.
abstract: The density of mucus glycoprotein compared to that of the corpus, antrum and duodenum was; 1.52, 1.49 and 1.57 g/ml respectively. Carbohydrate composition of gastrointestinal mucus glycoprotein consisted of N-acetylgalactosamine, N-acetylglucosamine, galactose, fucose and sialic acid. Ratios of carbohydrate composition among corpus, antral and duodenal mucus glycoproteins differed. The average length of an oligosaccharide was found to be about 12-13, 14 and 10 sugars in the corpus, antrum and duodenum, respectively. In the corpus, the amino acid content was found to have the following quantitative order: Thr greater than Ser greater than Glx = Pro; in the antrum: Thr greater than Ser greater than Glx; and in the duodenum: Thr greater than Ser greater than Pro. Corpus, antral and duodenal mucus glycoproteins have the blood-group A antigen; antral mucus glycoprotein in particular exhibited strong blood-group A activity.
mesh_terms: D000818:Animals; D002241:Carbohydrates / Q000032:analysis; D004386:Duodenum / Q000032:analysis*; D008297:Male; D009077:Mucins / Q000032:analysis*; D009928:Organ Specificity; D011706:Pyloric Antrum / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000032:analysis*
chemical_list: D002241:Carbohydrates; D009077:Mucins