Structural identification of the purine ring-opened form of N-(deoxyguanosin-8-yl)-4-aminoquinoline 1-oxide.
Alkaline pH treatment of N-(deoxyguanosin-8-yl)-4-amino-quinoline 1-oxide forms two quinoline derivatives. The two compounds were analyzed together by mass and 500 MHz 1H-n.m.r. spectroscopies and were identified as two 7,8-guanine ring-opened rotamers: 1-(1'-deoxyriboside)-1-[6-(2,5-diamino-4-oxo-pyrimidinyl)]-3-(4-quino linyl 1-oxide) urea.
D000634:Aminoquinolines; D003849:Deoxyguanosine / Q000031:analogs & derivatives*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry
D000634:Aminoquinolines; C032983:N-(deoxyguanosin-C(8)-yl)-4-aminoquinoline 1-oxide; D003849:Deoxyguanosine