Genetics of somatoform disorders.
I investigated the contribution of hereditary factors in somatoform disorders. Fourteen monozygotic and 21 dizygotic index twins and their co-twins were personally interviewed. The results showed a concordance of 29% in monozygotic and 10% in dizygotic pairs. However, similarity in childhood experience seemed to influence the concordance rates. Thus, even if somatoform disorders appear familial, the transmission may be environmental. Furthermore, the study showed a high frequency of anxiety disorders, especially generalized anxiety disorders, in the co-twins of somatoform-disordered twins.
D000328:Adult; D001008:Anxiety Disorders / Q000175:diagnosis / Q000209:etiology / Q000235:genetics; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D008297:Male; D008370:Manuals as Topic; D009664:Norway; D012801:Sibling Relations; D013001:Somatoform Disorders / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic