Isolation and characterization of new proteins produced by the infusion of colchicine in goat mammary gland.
Three new proteins have now been isolated from goat milk obtained after colchicine is infused into the mammary gland. Two of the proteins are proline-rich, and a third is a very acidic phosphoprotein. One of the proline-rich proteins is related compositionally to a sheep colostrum proline-rich protein, which has been shown to have a regulatory effect on the immune response (Janusz, M., Stavoscik, K., Zimecki, M., Wieczorek, Z., and Lisowski, J. (1981) Biochem. J. 199, 9-15). Other aspects of colchicine-treated milks are described.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002364:Caseins / Q000032:analysis; D002848:Chromatography, DEAE-Cellulose; D002850:Chromatography, Gel; D003078:Colchicine / Q000494:pharmacology*; D004589:Electrophoresis, Disc; D005260:Female; D006041:Goats; D008321:Mammary Glands, Animal / Q000032:analysis*; D008894:Milk Proteins / Q000302:isolation & purification*; D008970:Molecular Weight; D010758:Phosphorus / Q000032:analysis; D012967:Sodium Dodecyl Sulfate
D000596:Amino Acids; D002364:Caseins; D008894:Milk Proteins; D010758:Phosphorus; D012967:Sodium Dodecyl Sulfate; D003078:Colchicine