The role of Schmidt-Lanterman incisures in Wallerian degeneration.
The number of the Schmidt-Lanterman incisures and their intrasegmental distribution were studied at 36 h after transection of the rat sciatic nerve. Examination of teased, proximo-distally oriented, myelinated nerve fibers revealed no difference between the distal and the proximal stump. The results indicate that no proliferation of the incisures is required for the fiber fragmentation: numerous incisures are normally available in the midinternodal area where the degeneration begins.
D000818:Animals; D008297:Male; D009410:Nerve Degeneration; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains; D014855:Wallerian Degeneration