title: Association of secondary hyperparathyroidism with red cell survival in chronic haemodialysis patients.
abstract: 51Cr red cell mass (RCM), 51Cr red cell survival (RCS) and plasma parathyroid hormone (PTH) levels were measured in 27 stable chronic haemodialysis patients with a variable degree of clinical secondary hyperparathyroidism. Included were five patients who had had total parathyroidectomy. The results showed a strong negative correlation between PTH and RCS (r = -0.67, P less than 0.001) and a positive correlation between RCS and RCM (r = +0.53, P less than 0.005). However, the negative correlation between PTH and RCM was weak (r = -0.45, P less than 0.02). When the 13 patients with normal PTH levels (mean 0.18 +/- 0.12 microgram/l) were compared with the 14 patients with raised levels (mean 1.35 +/- 0.71 micrograms/l), there was a marked difference in RCS (P less than 0.005) but no difference in RCM.
mesh_terms: D000328:Adult; D000368:Aged; D004905:Erythrocyte Aging; D004911:Erythrocyte Volume; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000097:blood / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000601:surgery; D010281:Parathyroid Hormone / Q000097:blood; D006435:Renal Dialysis
chemical_list: D010281:Parathyroid Hormone