title: The rate of lateral diffusion of phospholipids in erythrocyte microvesicles.
abstract: 31P-NMR spectra of phospholipids in membranes of erythrocyte microvesicles isolated from outdated blood units were recorded in the temperature range 5 to 55 degrees C. Within that range the lineshape is strongly influenced by an increasing rate of lateral diffusion of phospholipids. At 36 degrees C a diffusion constant, D, of (2 +/- 1) X 10(-12) m2/s was obtained. The diffusion rate is by a factor of 3 to 10 greater than in erythrocyte membranes measured by the photobleaching technique and is comparable with values obtained for several lipid model membranes. The differences in lateral diffusion rates are probably connected with the depletion of microvesicle membranes in membrane proteins.
mesh_terms: D001809:Blood Viscosity; D004058:Diffusion; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005453:Fluorescence; D006801:Humans; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D010743:Phospholipids / Q000378:metabolism*; D013696:Temperature
chemical_list: D010743:Phospholipids