Atypical Cogan's syndrome: an autoimmune disease?
A 22-year-old woman is described with gastrointestinal complaints, sclerokeratitis, and a bilateral progressive hearing loss. The clinical picture, the outcome of lymphocyte stimulation tests against S antigen (retina soluble antigen), outer rod segment, and scleroprotein, and the successful administration of corticosteroids after a partial spontaneous hearing improvement, are suggestive of an autoimmune disease.
D000328:Adult; D001299:Audiometry; D001327:Autoimmune Diseases / Q000188:drug therapy; D003424:Crohn Disease / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000209:etiology*; D011241:Prednisone / Q000627:therapeutic use; D013577:Syndrome
D011241:Prednisone