title: Malignant peripheral nerve sheath tumor arising in an adrenal ganglioneuroma in an adult male homosexual.
abstract: The authors report a case of malignant peripheral nerve sheath tumor arising in an adrenal ganglioneuroma in an adult. This is the first such case occurring in the absence of a history of childhood neuroblastoma treated with radiation, and provides evidence that such a transformation can occur spontaneously. The neoplasm demonstrated a highly malignant biologic behavior with rapid growth, local recurrence, and metastasis.
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000209:etiology* / Q000473:pathology; D000328:Adult; D005729:Ganglioneuroma / Q000209:etiology* / Q000473:pathology; D006716:Homosexuality; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications; D008297:Male; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary; D009455:Neurofibroma / Q000209:etiology* / Q000473:pathology; D010524:Peripheral Nervous System Neoplasms / Q000209:etiology* / Q000473:pathology