[Dehydrogenase activity of pentose and glucuronate pathways of glucose utilization in the rat brain during single and repeated cooling].
Repeated supercoolings down to rectal temperatures (19-20 degrees C) results in the different changes in the dehydrogenase activity of pentose and glucuronate pathways in the rat brain: the activity of the pentose cycle oxidative enzymes (glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase) lowers considerably and that of VDP-glucose dehydrogenase rises. The dehydrogenase activity in the pentose cycle is found to be inhibited in rats cooled for the first time, the UDP-glucose dehydrogenase activity being preserved at the control level. In the adapted rats the cooling causes mobilization of the pentose cycle, the UDP-glucose dehydrogenase activity remains unchanged.
D000222:Adaptation, Physiological; D000818:Animals; D001921:Brain / Q000201:enzymology*; D005965:Glucuronates / Q000378:metabolism*; D007036:Hypothermia, Induced; D010088:Oxidoreductases / Q000378:metabolism*; D010427:Pentose Phosphate Pathway; D051381:Rats
D005965:Glucuronates; D010088:Oxidoreductases
Aktivnost' degidrogenaz pentoznogo i gliukuronatnogo puteĭ utilizatsii gliukozy v golovnom mozgu krys pri odnokratnykh i mnogokratnykh pereokhlazhdeniiakh.