title: A waterborne outbreak of hepatitis A in Meade County, Kentucky.
abstract: In November 1982, Meade County, Kentucky health officials noted a sudden increase in the incidence of hepatitis A. Using a standardized interview of 73 cases (68 serologically confirmed), and 85 controls (all negative for antibody to hepatitis A virus), the most important risk factor identified was household use of untreated water from a single spring. A dose-response relationship was found for consumption of unboiled spring water. Water samples taken from the spring during the outbreak were contaminated with fecal coliforms.
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks / Q000453:epidemiology*; D004812:Epidemiologic Methods; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D006801:Humans; D007223:Infant; D007629:Kentucky; D008297:Male; D012306:Risk; D014871:Water Microbiology; D014881:Water Supply