Binding of benzo(a)pyrene to rat lung glutathione S-transferases in vivo.
A highly selective in vivo binding of benzo(a)pyrene to rat lung glutathione S-transferases is demonstrated. Benzo(a)pyrene or its metabolites are specifically bound to Ya' and Yc subunits of rat lung glutathione S-transferases.
D000818:Animals; D001564:Benzo(a)pyrene / Q000378:metabolism*; D002250:Carbon Radioisotopes; D005982:Glutathione Transferase / Q000302:isolation & purification / Q000378:metabolism*; D007527:Isoenzymes / Q000302:isolation & purification / Q000378:metabolism; D007700:Kinetics; D008168:Lung / Q000201:enzymology*; D046911:Macromolecular Substances; D008297:Male; D011485:Protein Binding; D051381:Rats; D011919:Rats, Inbred Strains
D002250:Carbon Radioisotopes; D007527:Isoenzymes; D046911:Macromolecular Substances; D001564:Benzo(a)pyrene; D005982:Glutathione Transferase