title: Group-specific component (Gc) subtypes in Gambian and Transkeian populations: a description of a new variant.
abstract: A total of 270 serum specimens from Keneba and Manduar villages of The Gambia and 126 from Bantu of Transkei were examined for the group-specific component (Gc) phenotypes by isoelectric focusing. Only one individual showed phenotype 2-2 in the Bantu population, and the sub-allele frequencies showed a distribution very characteristic of African populations. A new rare mutation, Gc1C34, was found in heterozygous combination with Gc2 allele. The synthesis of the existing Gc sub-type data was examined for its anthropological implications.
mesh_terms: D000483:Alleles; D001789:Blood Group Antigens / Q000235:genetics*; D005714:Gambia; D005787:Gene Frequency; D005828:Genetics, Population; D006801:Humans; D007525:Isoelectric Focusing; D010641:Phenotype; D044469:Racial Groups; D013019:South Africa
chemical_list: D001789:Blood Group Antigens