Chronic human colchicine neuropathy and myopathy.
A 43-year-old woman who indiscriminately took colchicine for five years developed a progressive multisystem syndrome that included severe axonal neuropathy and a pathologically striking myopathy. The neuropathy and myopathy were similar to experimental animal colchicine-induced neuromuscular toxicity.
D000328:Adult; D001369:Axons; D002908:Chronic Disease; D003078:Colchicine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009135:Muscular Diseases / Q000139:chemically induced*; D009422:Nervous System Diseases / Q000139:chemically induced*
D003078:Colchicine