Creatine kinase MB in skeletal muscle and serum of spine-fusion patients.
The low specificity of creatine kinase (CK) MB elevations for myocardial infarction was confirmed by a prospective analysis of paraspinal muscle and postoperative serum levels of CK-MB. Eleven of 30 patients had serum elevations of CK-MB without myocardial infarction. Elevated CK-MB was not specific for myocardial infarction after spine surgery. CK-MB was found in paraspinal muscle of 93% of patients. CK-MB may be a pathologic marker in patients with spinal disease.
D000293:Adolescent; D000328:Adult; D003402:Creatine Kinase / Q000097:blood / Q000378:metabolism*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000201:enzymology*; D009203:Myocardial Infarction / Q000175:diagnosis*; D011183:Postoperative Complications / Q000175:diagnosis; D011184:Postoperative Period; D011446:Prospective Studies; D013123:Spinal Fusion
D007527:Isoenzymes; D003402:Creatine Kinase