Pseudomembranous colitis in a preterm neonate.
This preterm female infant abruptly developed diarrhea and bowel distention at 25 days of age and died within 60 h with fulminating pseudomembranous colitis and proctitis. Toxin-producing C. difficile was recovered from the stool. The pseudomembranous colitis developed 12 days after the last dose of ampicillin was given to the baby. Necrotizing enterocolitis, a condition pathologically distinct from pseudomembranous colitis, was also present.
D000667:Ampicillin / Q000009:adverse effects; D003015:Clostridium Infections; D004761:Enterocolitis, Pseudomembranous / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000209:etiology* / Q000473:pathology; D013997:Time Factors
D000667:Ampicillin