High frequency of anti-A and anti-B haemolysins in certain ethnic groups of Nigeria.
Out of 11,480 blood donors, 5,380 (46.9%) belonging to a blood group O were screened for the presence of anti-A and anti-B haemolysins. Strong haemolysins (complete lysis of A and/or B cells) were detected in 1,739 (32.3%) of these blood donors. A striking observation was the high frequency of these haemolysins amongst ethnic groups originating from the southern part of Nigeria. Possible causes and consequences during blood transfusion and pregnancy are discussed.
D000017:ABO Blood-Group System / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D005006:Ethnicity; D006460:Hemolysin Proteins / Q000276:immunology*; D006801:Humans; D007518:Isoantibodies / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009549:Nigeria
D000017:ABO Blood-Group System; D006460:Hemolysin Proteins; D007518:Isoantibodies