A cytogenetic study of embryonal rhabdomyosarcoma.
In the cytogenetic analysis of an embryonal rhabdomyosarcoma after short-term culture, individual cells were found to contain multiple copies of chromosomes #2, #6, #8, #12, #13, #18, #20 and #21, and del(1)(:p21----qter). The tumor was hypotriploid (mode, 56 chromosomes). The relationship between these findings and published reports of karyotypes from rhabdomyosarcoma is discussed.
D000782:Aneuploidy; D001859:Bone Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D002478:Cells, Cultured; D002648:Child; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D007621:Karyotyping; D011003:Ploidies; D012208:Rhabdomyosarcoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery