Familial tumor of the testis.
A survey of the literature since 1928 yields reports on 100 patients with testicular tumor occurring in families. From our own case material we present clinical data on 11 additional patients. Non-twin brothers are most often involved. Presently available data are too limited to assess the impact of a possible genetic disposition on the development of malignoma of the testis. Additional case reports and register studies are needed. Equally undecided is the question if sperm banking of testicular tumor patients prior to therapy carries any genetic risk to the progeny.
D000328:Adult; D004200:Diseases in Twins; D006801:Humans; D008297:Male; D008875:Middle Aged; D013074:Sperm Banks; D013736:Testicular Neoplasms / Q000235:genetics*