Sensitivity of lymphocytic choriomeningitis and Tacaribe viruses to several physical factors.
A comparative study was performed as regards the behaviour of lymphocytic choriomeningitis virus (LCMV)--strains Fo-2 and 522--and of Tacaribe virus (strain Tr 11573) at different temperatures and pH values. All the three arenavirus strains had a high thermosensitivity and were rapidly inactivated in an acid medium. LCMV was more sensitive to UV irradiation than Tacaribe virus. The effect of sonication was also investigated.
D000818:Animals; D000833:Animals, Suckling; D001116:Arenaviridae / Q000254:growth & development* / Q000472:pathogenicity / Q000528:radiation effects; D006863:Hydrogen-Ion Concentration; D008217:Lymphocytic choriomeningitis virus / Q000254:growth & development* / Q000472:pathogenicity / Q000528:radiation effects; D051379:Mice; D013045:Species Specificity; D013696:Temperature; D014466:Ultraviolet Rays