Pregnancy complicated by homozygous hypercholesterolemia.
The course of pregnancy in a woman with homozygous type IIa hypercholesterolemia is described. Despite prepartum cholesterol levels as high as 700 mg/dL, her cholesterol level increased further during gestation. Pathological examination of the placenta did not reveal insufficiency or vasculopathy.
D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000473:pathology*; D008264:Macrophages / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000473:pathology*