Schistosoma mansoni: exposure in vitro of adult male surface antigens.
Incubation of adult male Schistosoma mansoni for 24 hr in medium containing newborn calf serum or normal human plasma resulted in an increase in the amount of parasite antigen exposed at the worm surface. No effect was observed on the amount of host antigen which was present. The increase in the exposure of parasite antigens takes place progressively over 24 hr and is partially dependent on the presence of lipoproteins in the culture medium. The possibility is discussed that the increase is due to environmentally induced changes in surface membrane lipid composition.
D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D003470:Culture Media; D004912:Erythrocytes / Q000469:parasitology; D006790:Host-Parasite Interactions; D008074:Lipoproteins / Q000097:blood; D008297:Male; D051379:Mice; D012550:Schistosoma mansoni / Q000254:growth & development / Q000276:immunology*
D000947:Antigens, Helminth; D000954:Antigens, Surface; D003470:Culture Media; D008074:Lipoproteins