Rickets of prematurity: calcium and phosphorus supplementation.
Seventy-four infants weighing less than 1500 gm at birth were fed enterally from birth until day 47. Group A (18 infants) were given SMA Gold Cap: group B (18 infants), supplementary calcium to 21 mmol/L (84 mg/dl); group C (16 infants), further calcium supplementation to 31.2 mmol/L (125 mg/dl); and group D (22 infants), milk with calcium content 31.2 mmol/L (125 mg/dl) and phosphorus supplementation to 15.7 mmol/L (49 mg/dl). The addition of calcium reduced the radiologic evidence of rickets, and combined calcium and phosphorus supplementation maintained plasma alkaline phosphatase activity within the normal range for 6 weeks.
D000469:Alkaline Phosphatase / Q000097:blood; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000378:metabolism; D002118:Calcium / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D006801:Humans; D007225:Infant Food; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D010710:Phosphates / Q000097:blood; D010758:Phosphorus / Q000008:administration & dosage / Q000627:therapeutic use*; D011859:Radiography; D012279:Rickets / Q000097:blood / Q000000981:diagnostic imaging / Q000188:drug therapy*
D010710:Phosphates; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium