Histological changes in the penis of the Chacma baboon--a model to study aging penile vascular impotence.
Light and scanning electron microscopy was performed on the penes of Chacma baboons to establish their suitability as animal model for studying vascular impotence. Analogous aging penile vascular changes were found in man, and a fibrous trabeculopathy with intertrabecular senechiae was demonstrated. Considering the corresponding changes, the Chacma baboon could thus be regarded suitable for studying the pathophysiology of aging penile vascular changes.
D000375:Aging; D000818:Animals; D004195:Disease Models, Animal; D007172:Erectile Dysfunction / Q000473:pathology*; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D010215:Papio / Q000033:anatomy & histology; D010413:Penis / Q000098:blood supply / Q000473:pathology* / Q000648:ultrastructure