title: Crying-induced bronchospasm in childhood asthma: response to medical management.
abstract: Crying-induced bronchospasm (CIB), cough and/or wheeze greater than or equal to 5 minutes during or after crying behavior, is a common feature of childhood asthma. Sixty CIB patients were evaluated during a 6-month clinical treatment study consisting of environmental and pharmacologic (xanthines, beta-agonist stimulants, and corticosteroids) interventions. Both CIB (P = .007) and non-CIB (P = .0005) symptoms were significantly reduced. CIB asthma had lesser reduction in wheezing than non-CIB (P less than .001), suggesting that nebulized medication and/or behavioral interventions may be of benefit to further reduce CIB symptoms.
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000178:diet therapy / Q000188:drug therapy / Q000503:physiopathology* / Q000628:therapy; D001986:Bronchial Spasm / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D003448:Crying; D006801:Humans; D007167:Immunotherapy; D007223:Infant; D013806:Theophylline / Q000627:therapeutic use
chemical_list: D013806:Theophylline