title: Thrombosis of a prosthetic valve managed by thrombolysis: a case report.
abstract: Thrombosis of a prosthetic valve is one of the most serious cardiovascular events. Emergency replacement of the prosthetic valve has been the standard method of management but carries a high operative risk. This paper describes the successful use of streptokinase, given intravenously, to manage a patient with this complication in the acute phase. Eventually, operation was necessary because the presence of residual organized clot was suspected, but the procedure was performed electively 10 days later.
mesh_terms: D000328:Adult; D001022:Aortic Valve Insufficiency / Q000601:surgery; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D013300:Streptokinase / Q000627:therapeutic use*; D013927:Thrombosis / Q000209:etiology* / Q000628:therapy
chemical_list: D013300:Streptokinase