Rapid reversal of ergotamine-induced vasospasm.
Peripheral ischemia, secondary to ergotamine tartrate and caffeine suppositories is reported in a 48-year-old female. Lower extremity pre-gangrenous changes were unresponsive to surgical sympathectomy, calcium channel blockade, intra-arterial vasodilators and systemic anticoagulation. A dramatic clinical and radiological reversal of the vasospasm was obtained with intravenous sodium nitroprusside when surgical amputation appeared inevitable.
D000792:Angiography; D004878:Ergotamine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000139:chemically induced* / Q000188:drug therapy; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy; D009599:Nitroprusside / Q000627:therapeutic use
D009599:Nitroprusside; D004878:Ergotamine