High sensitivity of carnitine acyltransferase I to malonyl-CoA inhibition in liver of obese Zucker rats.
Carnitine acyltransferase of liver mitochondria prepared from obese Zucker rats has a higher sensitivity to inhibition by malonyl-CoA compared with carnitine acyltransferase of mitochondria prepared from lean Zucker rats.
D000214:Acyl Coenzyme A / Q000494:pharmacology*; D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000818:Animals; D002333:Carnitine Acyltransferases / Q000037:antagonists & inhibitors*; D005227:Fatty Acids / Q000378:metabolism; D008297:Male; D008316:Malonyl Coenzyme A / Q000494:pharmacology*; D008930:Mitochondria, Liver / Q000201:enzymology*; D009765:Obesity / Q000201:enzymology*; D051381:Rats; D011924:Rats, Zucker
D000214:Acyl Coenzyme A; D005227:Fatty Acids; D008316:Malonyl Coenzyme A; D000217:Acyltransferases; D002333:Carnitine Acyltransferases