DNA repair synthesis in the rat retina following in vivo exposure to 300-nm radiation.
Quantitative autoradiography was used to study the incorporation of 3H-thymidine into the retina of albino rats following in vivo exposure to 300-nm radiation. Relative to background labeling in unexposed eyes, there was 8-20 times as much label per unit area in the outer nuclear layer, inner nuclear layer, and ganglion cells of 300-nm exposed retinas. The photoreceptor inner segments also showed thymidine labeling in both control and exposed retinas.
D000818:Animals; D001345:Autoradiography; D004247:DNA / Q000096:biosynthesis*; D004260:DNA Repair / Q000528:radiation effects*; D008297:Male; D010786:Photoreceptor Cells / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000032:analysis / Q000378:metabolism / Q000528:radiation effects*; D013936:Thymidine / Q000378:metabolism; D014316:Tritium; D014466:Ultraviolet Rays
D014316:Tritium; D004247:DNA; D013936:Thymidine