Tentative evidence of Y-linked statural gene(s). Growth in the testicular feminization syndrome.
The linear growth data of 48 XY individuals, presumed to be androgen-insensitive as a consequence of the testicular feminization syndrome, were found to be similar to normal male standards and tall for normal female standards. These data are interpreted as evidence for one or more Y-linked gene function(s) which augment stature independently of testosterone effects.
D000293:Adolescent; D000328:Adult; D013734:Androgen-Insensitivity Syndrome / Q000235:genetics / Q000503:physiopathology*; D001827:Body Height; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D005260:Female; D008040:Genetic Linkage; D006128:Growth; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012727:Sex Characteristics; D012729:Sex Chromosome Aberrations / Q000235:genetics / Q000503:physiopathology*; D014998:Y Chromosome