Reconstituted high density lipoprotein behaviour is modified by the nature of the lipid vesicle.
Apo HDL is a more potent inhibitor of lipoprotein lipase than native HDL. HDL reconstituted from apo HDL and vesicles made from either HDL total lipids or HDL phospholipids inhibits lipoprotein lipase in the same manner as native HDL. HDL reconstituted from apo HDL and vesicles made from phosphatidylcholine and sphingomyelin still behaves like apo HDL.
D000818:Animals; D001053:Apolipoproteins / Q000378:metabolism*; D002784:Cholesterol; D005217:Fat Emulsions, Intravenous / Q000378:metabolism; D006868:Hydrolysis; D008071:Lipoprotein Lipase / Q000037:antagonists & inhibitors; D008075:Lipoproteins, HDL / Q000378:metabolism*; D010713:Phosphatidylcholines; D051381:Rats; D013109:Sphingomyelins
D001053:Apolipoproteins; D005217:Fat Emulsions, Intravenous; D008075:Lipoproteins, HDL; D010713:Phosphatidylcholines; D013109:Sphingomyelins; D002784:Cholesterol; D008071:Lipoprotein Lipase