Urological evaluation in the Shy Drager syndrome.
Nine patients with the Shy-Drager syndrome underwent complete urological and neurological investigation of bladder symptoms. Urodynamic studies revealed detrusor areflexia in 6 patients (67 per cent), detrusor hyperreflexia in 3 (33 per cent), a lower motor neuron lesion involving the periurethral striated muscle in 9 (100 per cent) and an open vesical neck at rest in all 5 patients in whom cystography was performed. These findings support the current view that parasympathetic, pudendal and sympathetic involvement is part of the pathophysiology of the Shy-Drager syndrome.
D000368:Aged; D001342:Autonomic Nervous System Diseases / Q000503:physiopathology*; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D012021:Reflex, Abnormal / Q000503:physiopathology*; D012791:Shy-Drager Syndrome / Q000150:complications / Q000503:physiopathology*; D014521:Urethra / Q000503:physiopathology; D001743:Urinary Bladder / Q000503:physiopathology*; D001750:Urinary Bladder, Neurogenic / Q000209:etiology / Q000503:physiopathology; D014554:Urination; D014563:Urodynamics