title: [Function of the blood-cerebrospinal fluid barrier and selected biochemical cerebrospinal fluid components in senile dementias of various types].
abstract: Some selected CSF and serum components were determined in demental patients classified by the Hachinski test into vascular and primary-degenerative groups. As for the vascular group, the frequency distribution of the serum/CSF albumin ratios characterizing the barrier function corresponds to that of controls, in primary-degenerative cases, however, it is shifted to higher values. In vascular dementia higher CSF LAP activities pointing to actual cell damaging processes in the CNS were found. The concentrations of lactate and some trace metals in CSF and serum are not suitable for differential diagnostic purposes.
mesh_terms: D000368:Aged; D000535:Aluminum / Q000134:cerebrospinal fluid; D001812:Blood-Brain Barrier; D003035:Cobalt / Q000134:cerebrospinal fluid; D003300:Copper / Q000134:cerebrospinal fluid; D003704:Dementia / Q000134:cerebrospinal fluid*; D006801:Humans; D007773:Lactates / Q000134:cerebrospinal fluid; D019344:Lactic Acid; D007931:Leucyl Aminopeptidase / Q000134:cerebrospinal fluid; D012709:Serum Albumin / Q000134:cerebrospinal fluid; D015032:Zinc / Q000134:cerebrospinal fluid
chemical_list: D007773:Lactates; D012709:Serum Albumin; D019344:Lactic Acid; D003035:Cobalt; D003300:Copper; D000535:Aluminum; D007931:Leucyl Aminopeptidase; D015032:Zinc
vernacular_title: Blut-Liquor-Schrankenfunktion und ausgewählte biochemische Liquor-komponenten bei Altersdemenzen verschiedenen Typs.