Surgical aspects of intestinal injury due to pelvic radiotherapy.
Seventy-one patients with intestinal injury secondary to pelvic irradiation had predominantly large bowel lesions. Seventeen cases were treated conservatively and 54 came to surgery, 28 patients having more than one operation. Following this essentially salvage surgery there were more ileal than colonic anastomotic leaks. Thirty-four patients died during the follow-up period (2-12 years), 19 from recurrent malignancy, and nine as a result of continuing radiation effects. Seventy per cent of the patients who had a radiation fistula died as a result of malignancy. Of 42000 cases of pelvic malignancy treated by irradiation over the decade 1972-1982, surgical referrals for complications constituted 1.7%, with an overall radiation-related mortality of 0.2%. It is our opinion that colostomy alone has little part to play in this condition, and a policy based on excisional surgery is suggested.
D000328:Adult; D000368:Aged; D003125:Colostomy; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D007412:Intestinal Fistula / Q000209:etiology / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000473:pathology / Q000601:surgery*