[Mechanism of inhibition of non-enzymatic fibrinolysis by a spleen factor].
Some data on the mechanism of inhibition of non-enzymatic fibrinolysis by a spleen factor are presented. It is demonstrated that the spleen protein factor which interacts with heparin at certain ratios forms a complex with the latter. As a result, the anticoagulating activity and properties of the spleen factor as a non-enzymatic fibrinolysis inhibitor are blocked.
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects*; D005337:Fibrin / Q000032:analysis*; D005340:Fibrinogen / Q000032:analysis*; D005342:Fibrinolysis / Q000187:drug effects*; D006493:Heparin / Q000097:blood / Q000494:pharmacology*; D008297:Male; D051381:Rats; D013154:Spleen / Q000032:analysis*
D005337:Fibrin; D005340:Fibrinogen; D006493:Heparin
O mekhanizme ingibirovaniia nefermentativnogo fibrinoliza faktorom selezenki.