title: Focal mucinosis in dogs: seven cases and review of cutaneous mucinoses of man and animals.
abstract: Seven dogs had one or more asymptomatic nodules, papules, or plaques on the skin or oral mucosa. The primary histologic feature was the accumulation of excess mucin within the dermis or submucosa. Based upon the clinical presentation and the histopathologic changes, it was proposed that these lesions represent the canine analogue of focal mucinosis in man, and that the same name be applied to the lesion in dogs. The criteria for the diagnosis of focal mucinosis were: (1) the presence of a single (rarely multiple) papule, nodule, or plaque which may be firm, rubbery, or soft, (2) the accumulation of mucin which disrupts and separates collagen fibers, (3) mild to extensive fibroblast proliferation, and (4) a mild mononuclear cell infiltration. The mucinoses of man and animals were reviewed.
mesh_terms: D000818:Animals; D003094:Collagen / Q000032:analysis; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000473:pathology / Q000662:veterinary*; D009061:Mouth Mucosa / Q000473:pathology; D009077:Mucins / Q000032:analysis*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology / Q000662:veterinary*
chemical_list: D009077:Mucins; D003094:Collagen