Plasma pyridoxal 5'-phosphate in women with the premenstrual syndrome.
Measurements of plasma pyridoxal 5'-phosphate (PLP) were made in 210 healthy premenopausal women, and related to their experience of the premenstrual syndrome (PMS). The 41 women (20 per cent) who had moderate or severe PMS were compared with 95 women (45 per cent) with no, or only slight, premenstrual symptoms: the former group were older and were more likely to have children, but there were no significant differences in smoking habits or mode of contraception. Plasma PLP values were similar in the two groups (mean values with s.d. 39.59 +/- 22.95 and 40.56 +/- 23.33 nmol/l respectively). We conclude that pyridoxine status, as measured by plasma PLP levels, is not altered in women with PMS and that pyridoxine deficiency is unlikely to contribute to the occurrence of this syndrome.
D000328:Adult; D003276:Contraceptives, Oral; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D008875:Middle Aged; D011293:Premenstrual Syndrome / Q000097:blood*; D011732:Pyridoxal Phosphate / Q000097:blood*; D012907:Smoking
D003276:Contraceptives, Oral; D011732:Pyridoxal Phosphate