Iron pigment in the brain of a man with tardive dyskinesia.
A 64-year-old man with bipolar affective disorder developed persistent tardive dyskinesia following an overdose of lithium and haloperidol. Two years later he died of unknown causes. Neuropathologic examination revealed extensive deposition of iron in basal ganglia and substantia nigra.
D001479:Basal Ganglia / Q000473:pathology*; D001714:Bipolar Disorder / Q000188:drug therapy; D004359:Drug Therapy, Combination; D004409:Dyskinesia, Drug-Induced / Q000209:etiology / Q000473:pathology*; D005911:Gliosis / Q000473:pathology; D006220:Haloperidol / Q000009:adverse effects; D006486:Hemosiderosis / Q000473:pathology; D006801:Humans; D007501:Iron / Q000032:analysis; D008094:Lithium / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D013378:Substantia Nigra / Q000473:pathology*
D008094:Lithium; D007501:Iron; D006220:Haloperidol