title: Aggressive fibromatosis. Report of two cases with rare clinicopathological manifestations.
abstract: Two cases of aggressive fibromatosis are described, one with tricentric origin and with the first tumor originating in the hand, the other with malignant transformation into a myxoid fibrosarcoma, grade III. The primary treatment of aggressive fibromatosis should be wide excision, and the follow-up should be long, taking into account the possibility of multicentricity and the risk of malignant transformation.
mesh_terms: D000293:Adolescent; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D002648:Child; D005350:Fibroma / Q000473:pathology* / Q000601:surgery; D005354:Fibrosarcoma / Q000473:pathology / Q000601:surgery; D006225:Hand; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008479:Mediastinal Neoplasms / Q000556:secondary; D012540:Scapula