Hypercalcemia in the neuroleptic malignant syndrome.
The neuroleptic malignant syndrome (NMS) developed in a 32-year-old man following fluphenazine enanthate administration. Hypercalcemia was initially present, perhaps reflecting release of calcium from skeletal muscle stores. The elevated serum calcium levels support the existence of a peripheral muscle abnormality in the pathogenesis of the NMS and provides another point of similarity between NMS and malignant hyperthermia.
D000328:Adult; D001480:Basal Ganglia Diseases / Q000150:complications*; D006801:Humans; D006934:Hypercalcemia / Q000150:complications* / Q000378:metabolism; D008297:Male; D008305:Malignant Hyperthermia / Q000150:complications / Q000378:metabolism; D009459:Neuroleptic Malignant Syndrome / Q000150:complications* / Q000378:metabolism