title: Comparison of porous titanium-surfaced and standard smooth-surfaced bone plates and screws in an unstable fracture model in dogs.
abstract: Bilateral midshaft femoral osteotomies were fixed with a 3-mm fracture gap in 6 dogs. In each dog, one femur was fixed with a porous titanium-surfaced bone plate and screws, whereas the opposite femur was fixed with a standard smooth-surfaced bone plate and screws. The mean removal torque for porous titanium-surfaced screws (32.3 kg X cm) was significantly (P less than 0.01) greater than the mean removal torque for standard screws (4.4 kg X cm). Osseous tissue ingrowth into the surface of porous titanium-surfaced screws was verified by histologic examination of the bone-screw interface. Radiographic and histologic examinations of the osteotomy gaps showed accelerated primary gap healing in osteotomies fixed with porous titanium-coated implants, compared with slower callus healing seen in osteotomies fixed with standard smooth-surfaced implants.
mesh_terms: D000818:Animals; D001860:Bone Plates; D001863:Bone Screws; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D005264:Femoral Fractures / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005269:Femur / Q000648:ultrastructure; D008297:Male; D008855:Microscopy, Electron, Scanning; D010027:Osteotomy; D011859:Radiography; D014025:Titanium
chemical_list: D014025:Titanium