title: [New observations in a case of Cronkhite-Canada syndrome].
abstract: We report about a 76 years old patient with Cronkhite-Canada syndrome. The diagnosis has been found with the following clinical symptoms: diarrhea, anorexia, alopecia, and onychotrophia. Laboratory values: severe hypoproteinemia (total serum protein 4.3 g/dl, albumin 2.4 g/dl); endoscopical and radiological findings: a generalized polyposis which involved the whole intestine except the oesophagus. As far as we saw in our literature-overview of 55 patients with Cronkhite-Canada syndrome, this patient had for the first time a carcinoma of the urinary bladder and a Bricker operation 17 years before the onset of his disease. Further we remarked a lack in the resorption of the enterally administered thyroidal hormones. The progress was fatal despite a parenteral hyperalimentation and a treatment with antibiotics and glucocorticoids.
mesh_terms: D000368:Aged; D000505:Alopecia / Q000175:diagnosis; D000855:Anorexia / Q000175:diagnosis; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D003967:Diarrhea / Q000175:diagnosis; D006801:Humans; D007037:Hypothyroidism / Q000175:diagnosis; D007417:Intestinal Polyps / Q000175:diagnosis*; D008297:Male; D009260:Nail Diseases / Q000175:diagnosis; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D011127:Polyps / Q000175:diagnosis*; D011183:Postoperative Complications / Q000175:diagnosis; D013274:Stomach Neoplasms / Q000175:diagnosis*; D013577:Syndrome; D001749:Urinary Bladder Neoplasms / Q000601:surgery
vernacular_title: Neue Beobachtungen bei einem Fall von Cronkhite-Canada-Syndrom.