title: [Possibilities and limitations of computerized tomography in the staging of the subdiaphragmatic spread of Hodgkin's disease].
abstract: The value of computed tomography in the assessment of subdiaphragmatic spread was studied prospectively in 72 patients with so far untreated, histologically confirmed Hodgkin's disease. In 17 patients (23.6%) computed tomography (CT) diagnosed subdiaphragmatic involvement, with no false-positive results. In 55 (76.4%) CT was within normal limits. In 30 patients exploratory laparotomy gave false-negative results in 7 (23.4%). The causes of false-negative results in CT are that lymph-nodes which were not enlarged but involved were not demonstrated and spleen involvement was not identified. Including those correctly positively diagnosed cases (17), CT had a sensitivity of 70.8% and a false-negative rate of 29.2%. It is concluded that when CT is within normal limits only exploratory laparotomy can with certainty exclude subdiaphragmatic involvement.
mesh_terms: D003951:Diagnostic Errors; D005188:False Negative Reactions; D005189:False Positive Reactions; D006529:Hepatomegaly / Q000175:diagnosis; D006689:Hodgkin Disease / Q000000981:diagnostic imaging*; D006801:Humans; D007813:Laparotomy; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008220:Lymphography; D009367:Neoplasm Staging; D014057:Tomography, X-Ray Computed
vernacular_title: Möglichkeiten und Grenzen der Computertomographie im Staging der subdiaphragmalen Ausbreitung des M. Hodgkin.