Prophylactic efficacy of lithium and its effective plasma levels in Chinese bipolar patients.
One hundred and one bipolar patients with at least two episodes during the 2 successive years prior to lithium received continuous lithium treatment for 2 years. The prophylactic efficacy of lithium increased from 60% to 73% when patients with individual standard deviations of plasma lithium of more than 0.2 mM/l were excluded. Most of the good responders showed individual mean plasma lithium levels from 0.5 mM/l to 0.79 mM/l.
D000328:Adult; D001714:Bipolar Disorder / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D005006:Ethnicity / Q000523:psychology*; D005260:Female; D006801:Humans; D008094:Lithium / Q000097:blood / Q000627:therapeutic use*; D008297:Male; D012008:Recurrence; D013624:Taiwan
D008094:Lithium