title: Disseminated aspergillosis in dogs.
abstract: Clinical and pathological findings are reported from a series of 12 cases of disseminated aspergillosis (A. terreus) in 11 German Shepherd dogs and one Dalmatian referred to Murdoch University Veterinary Hospital (MUVH) over the period 1980 to 1984. A preliminary study of humoral and cell mediated immune components and complement levels revealed no consistent abnormality in 9 dogs tested apart from raised IgG levels. Serum IgA levels were depressed in 30% of cases. Serial data from one extensively monitored case is presented. The unusual epidemiological and pathogenetic features of the disease are discussed.
mesh_terms: D000818:Animals; D001228:Aspergillosis / Q000276:immunology / Q000473:pathology / Q000662:veterinary*; D001842:Bone and Bones / Q000473:pathology; D003165:Complement System Proteins / Q000032:analysis; D004283:Dog Diseases / Q000276:immunology / Q000473:pathology*; D004285:Dogs; D005260:Female; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D007428:Intradermal Tests; D008214:Lymphocytes / Q000276:immunology; D008297:Male
chemical_list: D007136:Immunoglobulins; D003165:Complement System Proteins