[Preventive medical treatment of recurrent urinary calcium calculi].
In 59 out of 80 patients with recurrent renal calcium stones studied between 1977 and 1982 and followed up for 4,5 to 7 years, an index has been used to determine the activity of the disease, before and after treatment with diet, high water intake, thiazide and/or allopurinol. As estimated by variations of the "activity index", the treatment was effective in all groups studied: patients with idiopathic hypercalciuria were prescribed a low purine and oxalate diet and a large water intake associated or not with thiazide; hyperuricosuric patients were treated by the same diet and allopurinol; patients with no metabolic abnormality were submitted to diet and/or thiazide and/or allopurinol. The association of thiazide and allopurinol seems to be a more effective therapy in recurrent stone formers with primary hyperoxaluria than high diuresis and succinimide.
D000328:Adult; D000493:Allopurinol / Q000008:administration & dosage; D000584:Amiloride / Q000008:administration & dosage; D002118:Calcium / Q000652:urine*; D004231:Diuresis; D004359:Drug Therapy, Combination; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage; D007669:Kidney Calculi / Q000517:prevention & control* / Q000652:urine; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D013388:Succinimides / Q000008:administration & dosage
D013388:Succinimides; D006852:Hydrochlorothiazide; D000493:Allopurinol; D000584:Amiloride; D002118:Calcium
Traitement médical prophylactique des lithiases urinaires calciques récidivantes.