Does infection with environmental mycobacteria suppress the protective response to subsequent vaccination with BCG?
Using a guinea pig model of experimental airborne tuberculosis, we were unable to find evidence to support the hypothesis that infection with environmental mycobacteria (M. simiae or M. avium-intracellulare) interferes with the induction of a protective response in animals subsequently vaccinated with BCG.
D000818:Animals; D001500:BCG Vaccine / Q000276:immunology; D004195:Disease Models, Animal; D005260:Female; D006168:Guinea Pigs; D007194:India; D008297:Male; D009164:Mycobacterium Infections / Q000276:immunology; D009162:Mycobacterium avium; D014376:Tuberculosis / Q000276:immunology / Q000517:prevention & control*
D001500:BCG Vaccine