title: Transferrin variants in Tuscany (Italy). Evidence for two "new" Tf alleles.
abstract: Polyacrylamide gel isoelectric focusing (PAGIF) with carrier ampholytes was used for the determination of Tf phenotypes in a sample of 965 unrelated healthy blood donors from Tuscany (Italy). Thirteen rare variants in a heterozygote state were found (four Tf D, seven Tf B, and two rare Tf C subtypes). Among them two apparently new variants, tentatively called Tf C15 and Tf B4, were identified. The rare Tf B0 mutant was also observed.
mesh_terms: D000483:Alleles; D005260:Female; D006801:Humans; D007525:Isoelectric Focusing; D007558:Italy; D008297:Male; D010375:Pedigree; D010641:Phenotype; D014168:Transferrin / Q000235:genetics*
chemical_list: D014168:Transferrin