Production of group I pepsinogen by gastric carcinoma.
Group I pepsinogen levels were determined in the homogenized supernatant of the lymph nodes with metastasis of the gastric carcinoma by radioimmunoassay. Mean levels of group I pepsinogen were 941 ng/g and some of the lymph nodes showed very high levels compared with those of non-metastatic lymph nodes, 269 ng/g. They were also significantly higher than those of the sera in the same subjects, that is, the production of group I pepsinogen by gastric carcinoma was clarified.
D006801:Humans; D008198:Lymph Nodes / Q000378:metabolism; D008223:Lymphoma / Q000378:metabolism; D009362:Neoplasm Metastasis; D010435:Pepsinogens / Q000096:biosynthesis*; D011863:Radioimmunoassay; D013274:Stomach Neoplasms / Q000378:metabolism* / Q000473:pathology
D010435:Pepsinogens