title: The key role of sex dependency on kidney citrate metabolism in the rat.
abstract: An evaluation of the potential role of the kidney in the regulation of the blood citrate level under different acid-base statuses and various diets was performed. Twenty-four hours after bilateral nephrectomy there was a highly significant increase in the blood citrate concentrations in female rats, whereas the blood citrate levels either remained unchanged or decreased in bilateral nephrectomized male animals. Our data clearly indicate a key role of sex dependency on kidney citrate metabolism in the rat.
mesh_terms: D020155:3-Hydroxybutyric Acid; D000136:Acid-Base Equilibrium; D000818:Animals; D002951:Citrates / Q000378:metabolism*; D019343:Citric Acid; D005260:Female; D006885:Hydroxybutyrates / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D008297:Male; D009392:Nephrectomy; D051381:Rats; D011919:Rats, Inbred Strains; D012737:Sex Factors; D013217:Starvation
chemical_list: D002951:Citrates; D006885:Hydroxybutyrates; D019343:Citric Acid; D020155:3-Hydroxybutyric Acid