title: Relationship of pregnanediol level to cognitive behavior and mood.
abstract: This work examines data secured from a larger study relating cognitive behavior and mood in women to variation in estrogen level. The larger study noted that performance tended to be better during the luteal phase. The present analysis looks at the relationship of urinary pregnanediol levels with mood and cognitive behaviors. Thirty women with non-oral contraceptive-controlled menstrual cycles were tested during the luteal phase on a battery of cognitive tests and a variation of the Clyde Mood Scale. The cognitive tests were selected based upon the automatization versus perceptual restructuring dimensions described by Broverman and colleagues. Pregnanediol levels were measured in 24-hour urine specimens collected on the same day. Results show a significant relationship of pregnanediol level with mental subtraction and with time estimation. Perceptual restructuring tasks in general (perceptual restructuring index) showed a significant positive relationship with pregnanediol levels. Mood, however, was not found to be related to pregnanediol levels.
mesh_terms: D000328:Adult; D003071:Cognition / Q000187:drug effects*; D004644:Emotions / Q000187:drug effects*; D005260:Female; D006801:Humans; D008183:Luteal Phase; D008433:Mathematics; D011276:Pregnanediol / Q000097:blood / Q000502:physiology*; D014796:Visual Perception / Q000187:drug effects
chemical_list: D011276:Pregnanediol