title: Amino terminal sequence analysis of human placenta aromatase.
abstract: The amino acid composition and the amino-terminal amino acid sequence from position 1 to 21 of human placenta aromatase were determined. In addition, a cysteine containing peptide with a sequence homologous to those of peptides containing the cysteine residue which was suggested to provide the proximal thiolate ligand to the heme in other cytochrome p-450 isozymes, was identified. The results indicate that aromatase is a cytochrome p-450 protein, probably derived from a new cytochrome p-450 family.
mesh_terms: D000595:Amino Acid Sequence; D001141:Aromatase; D003545:Cysteine; D003577:Cytochrome P-450 Enzyme System; D005260:Female; D006801:Humans; D010446:Peptide Fragments; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy
chemical_list: D010446:Peptide Fragments; D003577:Cytochrome P-450 Enzyme System; D001141:Aromatase; D003545:Cysteine