Consistent reversal of abnormal DSTs after different antidepressant therapies in a patient with dementia.
The authors present a longitudinal case study of a 57-year-old man whose initial symptoms consisted of depression and dementia associated with an abnormal dexamethasone suppression test (DST). Antidepressant therapy resulted in consistent reversal of the DST and partial remission of the patient's vegetative signs. Nevertheless, the patient's condition deteriorated over 36 months to end-stage dementia.
D000639:Amitriptyline / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003704:Dementia / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D003907:Dexamethasone; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009661:Nortriptyline / Q000627:therapeutic use; D014196:Trazodone / Q000627:therapeutic use
D000928:Antidepressive Agents; D000639:Amitriptyline; D003907:Dexamethasone; D009661:Nortriptyline; D007099:Imipramine; D006854:Hydrocortisone; D014196:Trazodone