Demyelinating encephalopathy in Lyme disease.
A 38-year-old man from southeastern Connecticut developed a diffuse encephalopathy with partial complex seizures, followed weeks later by arthritis, cryoglobulinemia, and increased serum IgM. CT showed confluent low-density lesions in the deep cerebral white matter consistent with demyelination. Neither the encephalopathy nor the CT abnormalities improved. Lyme disease was diagnosed serologically 4 years later.
D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis; D002540:Cerebral Cortex; D003711:Demyelinating Diseases / Q000175:diagnosis; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis*; D008297:Male; D012640:Seizures / Q000175:diagnosis