title: [Levels and intracellular distribution of calcium and magnesium in the myometrium].
abstract: Atom-absorption spectrophotometry have shown that the content of Ca2+ in the rabbit and cow myometrium amounts to 4.54 +/- 0.47 and 2.57 +/- 0.30 and that of Mg2+--3.89 +/- 0.15 and 1.35 +/- 0.17 mmol per 1 kg of wet tissue weight, respectively, The content of Mg2+ in the myometrium is two times lower than in the myocardium and three times lower than in the skeletal muscle. During pregnancy (the day before delivery), delivery and postdelivery period the Ca2+ content in the rabbit myometrium is 1.5-2 times lower than in the state of functional rest, and its specific content in fractions of nuclei, mitochondria, microsomal and plasma membranes is practically the same (100-140 nmol per 1 mg of fraction protein). Distribution of the total Ca content calculated per fraction protein satisfies the following series: soluble fraction (56.4%) greater than nuclei (23.6% greater than mitochondria (7.4%) greater than microsomes (1.9%) greater than or equal to plasma membranes (1.3%). The highest specific content of Mg2+ is observed in the fraction of: plasma membranes--52, then mitochondria--40, microsomes--27 and nuclei--19 nmol per 1 mg of protein. The distribution of the total content of this element is described by a series: soluble fraction (71.8%) greater than nuclei (8.3%) greater than mitochondria (4.6%) greater than plasma membranes (1.7%) greater than microsomes (0.4%).(ABSTRACT TRUNCATED AT 250 WORDS)
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002417:Cattle; D005260:Female; D008274:Magnesium / Q000378:metabolism*; D009215:Myometrium / Q000378:metabolism*; D049590:Postpartum Period; D011247:Pregnancy; D011817:Rabbits; D013054:Spectrophotometry, Atomic; D013347:Subcellular Fractions / Q000378:metabolism
chemical_list: D008274:Magnesium; D002118:Calcium
vernacular_title: Soderzhanie i vnutrikletochnoe raspredelenie kal'tsiia i magniia v miometrii.