Psychopharmacologic and clinical correlates of attention in chronic schizophrenia.
Distractibility and reaction time were measured in 25 clinically stable chronic schizophrenic subjects receiving psychotropic medications. Higher serum neuroleptic levels were associated with lessened distractibility. Extrapyramidal side effects and level of symptoms were each related to slow and variable reaction times.
D000328:Adult; D000553:Ambulatory Care; D001288:Attention / Q000187:drug effects*; D001480:Basal Ganglia Diseases / Q000139:chemically induced / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000097:blood / Q000494:pharmacology; D011597:Psychomotor Performance / Q000187:drug effects; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D011930:Reaction Time / Q000187:drug effects; D012559:Schizophrenia / Q000188:drug therapy*; D012565:Schizophrenic Psychology
D010276:Parasympatholytics; D011619:Psychotropic Drugs