[Evaluation of the prognostic factors in patients with stage-I and -II ovarian cancer treated by an operation + irradiation variant].
The results of combined treatment (surgery and postoperative radiotherapy) in the group of 240 patients with stage I and II ovarian carcinoma were evaluated. The following factors were found to be important for prognosis: (I) removal of clinically detectable cancer sites during primary surgery (60.7% of 5-year survivals versus 19.4% of cases of surgery described by the surgeon as non-radical); (2) stage of tumor: 62.2% of survivals at stage I as compared with 28.3% at stage II; 73.9% at stage I without changes in the capsule of tumor against 56.9% in the other groups with the same stage; 45.5% at stage IIa versus 22.9% at stages IIb and IIc; (3) low differentiation of ovarian carcinoma which reduces curability to 44.9% in cases of stage I and IIa tumors. Five-year survival rates were higher, though statistically insignificant in those patients with stage Ia(i) and Ib(i) in whom intravaginal radium was applied (81.8%), and in those with stages Ia(ii), Ib(ii) and Ic in whom the whole abdomen was irradiated (64.5%). No statistically significant differences in relation to age, type of surgery, size of tumor identified during the first operation or type of teleradiotherapy (conventional roentgenotherapy or telecobalt therapy) were found.
D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D003536:Cystadenocarcinoma / Q000401:mortality / Q000473:pathology / Q000628:therapy; D005260:Female; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D010052:Ovariectomy; D011044:Poland; D011182:Postoperative Care; D011379:Prognosis; D011879:Radiotherapy Dosage
Otsenka faktorov prognoza u bol'nykh rakom iaichnika I i II stadiĭ, lechennykh po variantu "operatisiia + obluchenie".