Investigation of human plasma low density lipoprotein by three-dimensional fluorescence spectroscopy.
Human plasma LDL exhibits a diffuse fluorescence (excitation 360 nm) in the 400-600 nm range. Application of three-dimensional fluorescence spectroscopy shows the presence of 7 fluorophores in the lipid and 6 fluorophores in the protein domain. The 430 nm fluorescence in freshly prepared LDL and its apo-B is most likely indicative for remnants of in vivo lipid peroxidation.
D001055:Apolipoproteins B / Q000097:blood; D006801:Humans; D008054:Lipid Peroxides / Q000378:metabolism; D008077:Lipoproteins, LDL / Q000097:blood*; D013050:Spectrometry, Fluorescence
D001055:Apolipoproteins B; D008054:Lipid Peroxides; D008077:Lipoproteins, LDL