title: Additive variation maintained under stabilizing selection: a two-locus model of pleiotropy for two quantitative characters.
abstract: A model with two diallelic loci controlling two additive quantitative characters is suggested. One of the loci has a similar effect on both characters, whereas the second locus has an antagonistic effect on two characters. Both characters experience direct stabilizing selection. The model yields a stable polymorphic state, with both characters maintaining genetic variation. The genetic correlation between the characters at the equilibrium is zero, in spite of the pleiotropic effects of the loci controlling them.
mesh_terms: D000483:Alleles; D000818:Animals; D005796:Genes; D014644:Genetic Variation; D008433:Mathematics; D008957:Models, Genetic; D010641:Phenotype; D012641:Selection, Genetic