Lack of direct inhibitory action of oxytocin on progesterone production by dispersed cells from human corpus luteum.
Suspensions of luteal cells were prepared from samples of human corpora lutea obtained during the luteal phase of menstrual cycles. Addition of oxytocin (1 mumol/l) to the various cell preparations had no effect on either basal production of progesterone or on steroidogenic responses to a range of concentrations of gonadotrophin.
D000328:Adult; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D003338:Corpus Luteum / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008183:Luteal Phase; D010121:Oxytocin / Q000494:pharmacology*; D011374:Progesterone / Q000096:biosynthesis*
D006063:Chorionic Gonadotropin; D011374:Progesterone; D010121:Oxytocin