[Use of meradin for normalizing catecholamine metabolism in the rat hypothalamus at late periods following irradiation].
Meradine administered in a dose of 2 mg/kg during 10 days 10-12 months after irradiation with a dose of 4 Gy normalized the catecholamine metabolism in rat hypothalamus. The content of noradrenaline was restored as early as 24 h and that of DOPA and dopamine, 1 month after the cessation of meradine injection.
D000225:Adenine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D007031:Hypothalamus / Q000378:metabolism*; D011833:Radiation Injuries, Experimental / Q000188:drug therapy / Q000378:metabolism*; D051381:Rats; D013997:Time Factors
D002395:Catecholamines; C001700:meradine; D000225:Adenine
Primenenie meradina dlia normalizatsii obmena katekholaminov v gipotalamuse krys v otdalennye sroki posle oblucheniia.