Sinonasal cancer and exposure to softwood.
In order to study the connection between occupation and sinonasal cancer we have reviewed the files and histological sections of 70 patients (24 females and 46 males) treated at the Department of Oto-rhino-laryngology, National Hospital of Norway. Detailed information concerning previous occupations was obtained by telephone interviews according to a standardized questionnaire. This pilot study revealed a strong association between wood dust exposure and sinonasal cancer. Of 12 wood dust exposed men, 11 had been exposed exclusively to softwood. While squamous cell carcinoma was the predominant type of cancer in joiners, carpenters and loggers, non-Hodgkin lymphomas appeared to be associated with employment in saw- and planingmill firms. A nationwide case-control study is under preparation for further substantiation of the health hazards connected with exposure to softwood and other possible occupational factors related to sinonasal cancer.
D000230:Adenocarcinoma / Q000209:etiology; D000328:Adult; D000368:Aged; D004391:Dust / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000209:etiology; D009669:Nose Neoplasms / Q000209:etiology*; D009784:Occupational Diseases / Q000209:etiology*; D010255:Paranasal Sinus Neoplasms / Q000209:etiology*; D012306:Risk; D014934:Wood
D004391:Dust