A delayed hemolytic transfusion reaction due to anti-Cob.
A delayed hemolytic transfusion reaction precipitated by anti-Cob is described in a multiple transfused primigravida woman with sickle-cell disease. Sixteen days after the prophylactic transfusion of the first of 4 units of red cells, she experienced a fall in hemoglobin concentration accompanied by a newly positive antibody screen and direct antiglobulin test. Anti-Cob was identified both in the patient's serum and in an eluate prepared from her red cells.
D000328:Adult; D000743:Anemia, Hemolytic / Q000097:blood / Q000209:etiology*; D000755:Anemia, Sickle Cell / Q000150:complications / Q000628:therapy; D001789:Blood Group Antigens / Q000276:immunology*; D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000502:physiology*; D013997:Time Factors; D065227:Transfusion Reaction
D001789:Blood Group Antigens; D007518:Isoantibodies