Altered CSF protein pattern in a case of mycosis fungoides with nervous system involvement.
We report the clinical, neurophysiological and CSF study in a case of mycosis fungoides with nervous system involvement. The CSF contained an abnormal protein of molecular weight 22000 that was not in the patient's serum or in the CSF of control subjects and that disappeared after intrathecal immunosuppressive therapy. The nature of this protein is discussed in the light of hypothesis regarding the pathogenesis of the disease.
D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000134:cerebrospinal fluid* / Q000188:drug therapy / Q000532:radiotherapy; D009423:Nervous System Neoplasms / Q000134:cerebrospinal fluid* / Q000188:drug therapy / Q000532:radiotherapy; D012878:Skin Neoplasms / Q000134:cerebrospinal fluid* / Q000188:drug therapy / Q000532:radiotherapy
D002556:Cerebrospinal Fluid Proteins; D007166:Immunosuppressive Agents