Changes in liver glutathione S-transferase activities in Coturnix quail fed municipal sludge-grown cabbage with reduced levels of glucosinolates.
Cabbage, green beans, or seeds from sunflowers grown either on municipal sewage sludge-amended soil or soil alone were fed to male and female Coturnix quail, as 50% of a complete diet, for 5 weeks. Specific activities of liver glutathione S-transferase (GST) were similar in all quail fed the latter two plant diets and also similar to quail fed a nonplant, control diet. Sludge-grown cabbage-treated quail exhibited liver GST activities significantly higher (P less than 0.05) than levels of liver GST in birds fed the other plants, with a further twofold activity increase in quail fed the soil-grown cabbage. This response seems to be correlated with the levels of glucosinolates present in the cabbage, i.e., 3040 and 9253 ppm (dry basis) in the sludge-grown and soil-grown cabbage, respectively.
D000821:Animal Feed / Q000009:adverse effects; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D001937:Brassica / Q000032:analysis; D003370:Coturnix; D004032:Diet / Q000009:adverse effects; D005260:Female; D005961:Glucosinolates / Q000032:analysis / Q000494:pharmacology*; D005982:Glutathione Transferase / Q000378:metabolism*; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D051379:Mice; D009369:Neoplasms / Q000139:chemically induced; D051381:Rats; D013865:Thioglycosides / Q000494:pharmacology*
D005961:Glucosinolates; D013865:Thioglycosides; D005982:Glutathione Transferase