Deuterium NMR study of head-group deuterated phosphatidylserine in pure and binary phospholipid bilayers. Interactions with monovalent cations Na+ and Li+.
Head-group deuterated 1,2-dimyristoyl-sn-glycero-3-phosphorylserine (DMPS) was synthesized. 2H NMR spectra reflect the ionic strength-dependent polymorphism of DMPS aqueous dispersions. Results obtained with pure DMPS and mixed bilayers with phosphatidylcholine or phosphatidylethanolamine at various NaCl or LiCl concentrations indicate that interactions with Na+ and Li+ have very different effects upon the head-group quadrupole splittings.
D003903:Deuterium; D008051:Lipid Bilayers / Q000378:metabolism; D008094:Lithium / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008567:Membranes, Artificial; D009994:Osmolar Concentration; D010718:Phosphatidylserines / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
D008051:Lipid Bilayers; D008567:Membranes, Artificial; D010718:Phosphatidylserines; C042859:dimyristoylphosphatidylserine; D008094:Lithium; D012964:Sodium; D003903:Deuterium