Experimental evaluation of gastric banding for treatment of morbid obesity in pigs.
The effectiveness and complications of gastric banding were evaluated in 15 miniature pigs. A Gore-tex or Dacron graft was employed to encircle the stomach. The animals were divided into five groups, three pigs in each group. Group 1 had a 13 mm pouch stoma with a Gore-tex band, Group 2 had a 16 mm pouch stoma with a Gore-tex band, Group 3 had a 13 mm pouch stoma with a Dacron band, Group 4 had a 16 mm pouch stoma with a Dacron band, and Group 5 had a sham operation. The weight variation in the control group was significantly higher than that in the other groups at the ninth postoperative week (p less than 0.05). There was no significant difference among Groups 1, 2, 3, and 4. The gastric band had migrated distally in seven pigs. It was located in the body of the stomach in four animals and in the pylorus in three. These three pigs died from stenosis of the pylorus. The band had eroded and penetrated all stomach layers in three other animals. There was no difference in the incidence of postoperative complications between the Gore-tex and Dacron band groups. The use of this simple operation in the treatment of the morbidly obese patient should be applied with caution.
D000818:Animals; D001835:Body Weight; D003250:Constriction / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D005260:Female; D005774:Gastrostomy; D008297:Male; D009765:Obesity / Q000601:surgery*; D011707:Pyloric Stenosis / Q000209:etiology; D013270:Stomach / Q000601:surgery*; D013552:Swine; D013556:Swine, Miniature; D000267:Tissue Adhesions / Q000209:etiology