title: Acro-osteolysis associated with hypertrophic pulmonary osteoarthropathy and pachydermoperiostosis.
abstract: The authors report two cases of marked acro-osteolysis. One patient, a 16-year-old boy, had hypertrophic pulmonary osteoarthropathy associated with bronchiectasis, clubbing of the digits, synovitis, and osseous changes. The other patient, a 55-year-old man, had pachydermoperiostosis as well as synovial hypertrophy, clubbing of the digits, blepharitis, and a cataract. While the association of acro-osteolysis and pachydermoperiostosis has been reported before, this appears to be the first verified case of acro-osteolysis combined with hypertrophic pulmonary osteoarthropathy.
mesh_terms: D000293:Adolescent; D001862:Bone Resorption / Q000209:etiology*; D005385:Fingers / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010004:Osteoarthropathy, Primary Hypertrophic / Q000150:complications* / Q000000981:diagnostic imaging; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000150:complications* / Q000000981:diagnostic imaging; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000209:etiology*; D011859:Radiography; D014034:Toes / Q000000981:diagnostic imaging*