Benign cephalic histiocytosis. A case report and ultrastructural study.
A 4-year-old Hispanic boy had an asymptomatic eruption of red-brown macules and papules on the face, neck, trunk, and upper extremities. Examination of the skin lesions by light microscopy revealed a diffuse infiltrate of histiocytes in the upper dermis. Examination by electron microscopy showed wormlike inclusion bodies within the histiocytes. A diagnosis of benign cephalic histiocytosis was made on the basis of these distinct clinical, histologic, and ultrastructural features.
D001706:Biopsy; D002675:Child, Preschool; D006644:Histiocytes / Q000648:ultrastructure*; D006801:Humans; D007425:Intracellular Membranes / Q000648:ultrastructure; D008206:Lymphatic Diseases / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000648:ultrastructure*