Uteroplacental blood flow measurement using radioisotopes in small placentas.
In 25 pregnant females with a placental weight below the 20th percentile uteroplacental blood flow measurements using 113mIn-transferrin were performed in the 3rd trimester of pregnancy. Twelve patients with pregnancy-induced hypertension (PIH) were compared to 13 females with normal blood pressures. The results of uteroplacental blood flow measurements showed normal flow patterns in only 6 of the 25 subjects and were significantly worse in the group with PIH. Babies of patients with PIH had a mean birth weight of 1,100 g at a mean gestational age of 34.2 weeks versus 1,752 g and 37.4 weeks for newborns without PIH. Perinatal mortality was significantly higher in the PIH group. In combination with a small placenta PIH compounds the fetal risk.
D000328:Adult; D001724:Birth Weight; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D007204:Indium; D007231:Infant, Newborn; D010920:Placenta / Q000098:blood supply* / Q000473:pathology; D010922:Placenta Diseases / Q000175:diagnosis*; D010927:Placental Insufficiency / Q000175:diagnosis* / Q000473:pathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology; D011868:Radioisotopes; D014168:Transferrin; D014599:Uterus / Q000098:blood supply*
D011868:Radioisotopes; D014168:Transferrin; D007204:Indium