Electroretinographic recovery from controlled total ischemia.
Three groups of animals were studied during the four-hour period following their recovery from total occlusion of retinal circulation for periods of 30, 60 and 90 minutes. During incremental increases of ischemia, recovery followed a pattern that is the reverse of that previously reported, inasmuch as wave amplitude is concerned. From total extinction, ERGs recovered and showed hyperresponses. Delays, however, behaved differently: they increased with recovery time--the opposite of what was expected. All signs were inversely proportional to the duration of ischemia. Sixty minutes of occlusion appears to be a threshold beyond which ERGs do not recover as well.
D000818:Animals; D004596:Electroretinography; D007511:Ischemia / Q000503:physiopathology*; D011817:Rabbits; D012160:Retina / Q000098:blood supply* / Q000503:physiopathology; D013997:Time Factors