title: Circling behavior induced by phencyclidine in mice and its inhibition by naloxone.
abstract: Phencyclidine (PCP), when given to mice, induces general hyperactivity and rapid circling, similar to that caused by morphine. These effects are partially antagonized by naloxone.
mesh_terms: D000818:Animals; D007700:Kinetics; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009020:Morphine / Q000494:pharmacology; D009043:Motor Activity / Q000187:drug effects*; D009270:Naloxone / Q000494:pharmacology*; D010622:Phencyclidine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D012399:Rotation
chemical_list: D009270:Naloxone; D009020:Morphine; D010622:Phencyclidine