title: Conformations of alternating purine-pyrimidine DNAs in high-CsF solutions and their reversal by dipyrandium, ethidium and high temperature.
abstract: Chiroptical properties of synthetic DNAs with alternating purine-pyrimidine sequences were studied in high-CsF solutions. It was found that this salt transformed all the DNAs to non-canonical conformations like Z or X, which show striking negative bands in the long wavelength part of the CD spectra. The negative bands were reversed upon interaction with dipyrandium, ethidium and at high temperature.
mesh_terms: D000818:Animals; D002417:Cattle; D002586:Cesium; D002942:Circular Dichroism; D004247:DNA / Q000378:metabolism*; D004996:Ethidium / Q000494:pharmacology*; D005459:Fluorides; D006358:Hot Temperature; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D011067:Poly dA-dT / Q000378:metabolism; D011089:Polydeoxyribonucleotides / Q000378:metabolism; D011759:Pyrrolidines / Q000494:pharmacology*; D012996:Solutions
chemical_list: D011089:Polydeoxyribonucleotides; D011759:Pyrrolidines; D012996:Solutions; D002586:Cesium; D011067:Poly dA-dT; C019530:poly(dC-dG); C004861:dipyrandium; D004247:DNA; D004996:Ethidium; D005459:Fluorides; C027754:cesium fluoride