Translocation t(1;5) in a case of carcinoma of the cervix.
We report a case of carcinoma of the cervix uteri, which presented both numerical and structural chromosome changes. The tumor showed the coexistence of lines with different modal chromosome numbers, but all of them with the t(1;5)(q25;132). We also observed the presence of double minutes, dicentric chromosomes, small acentric fragments, and/or tri- and quadriradial figures in 11% of the cells.
D000328:Adult; D002900:Chromosomes, Human, 1-3; D002905:Chromosomes, Human, 4-5; D005260:Female; D006801:Humans; D014178:Translocation, Genetic; D002583:Uterine Cervical Neoplasms / Q000235:genetics*