The prevalence of diabetes mellitus in the family history of patients with primary glaucoma.
The prevalence of diabetes mellitus in the family history of 371 patients with primary glaucoma--closed-angle glaucoma, ocular hypertension and open-angle glaucoma--and 85 age- and sex-matched control subjects was determined. There was a significantly-increased prevalence of familial type 2 diabetes mellitus (non-insulin dependent diabetes mellitus) in patients with closed-angle glaucoma (p = 0.004) and ocular hypertension (p = 0.02). Primary glaucoma was not associated with familial type 1 diabetes mellitus (insulin dependent diabetes mellitus). The implications are discussed.
D000368:Aged; D003920:Diabetes Mellitus / Q000453:epidemiology* / Q000235:genetics; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology / Q000235:genetics; D004739:England; D005901:Glaucoma / Q000235:genetics*; D005902:Glaucoma, Open-Angle / Q000235:genetics; D006801:Humans; D008875:Middle Aged; D009798:Ocular Hypertension / Q000235:genetics