title: The histopathology of familial exudative vitreoretinopathy. A report of two cases.
abstract: Two eyes were enucleated for angle-closure associated with familial exudative vitreoretinopathy. Characteristic features included total retinal detachment, peripheral retinal vascular proliferation, and a fibrovascular preretinal membrane. Angle-closure glaucoma developed in one case when sudden massive subretinal hemorrhage, associated with abnormal intraretinal vessels, produced anterior displacement of the lens-iris diaphragm; in the second case, angle-closure was associated with the development of rubeosis iridis. Intraretinal inflammatory cells and exudates were also seen in the enucleated eyes.
mesh_terms: D000328:Adult; D002648:Child; D005128:Eye Diseases / Q000150:complications / Q000235:genetics / Q000473:pathology; D005260:Female; D005901:Glaucoma / Q000209:etiology; D006801:Humans; D008297:Male; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000235:genetics / Q000473:pathology; D012164:Retinal Diseases / Q000150:complications / Q000235:genetics* / Q000473:pathology; D014822:Vitreous Body / Q000473:pathology