Macrophages in the urogenital ridge of the mid-gestation mouse fetus.
Isolated urogenital ridges from mouse embryos 11 1/2-16 1/2 days post coitum were separated into genital ridge and mesonephric areas; the latter were then cut into small fragments and cultured as explants on glass or plastic. The explants soon became surrounded by flat outgrowths of cells, followed by a population of large round granular cells. The behaviour of these cells, first on the outgrowth and then on the glass is described. Evidence is presented that they are fetal macrophages.
D000818:Animals; D002465:Cell Movement; D002478:Cells, Cultured; D005260:Female; D005333:Fetus; D005854:Germ Cells / Q000648:ultrastructure; D008264:Macrophages / Q000648:ultrastructure*; D008297:Male; D008650:Mesonephros / Q000648:ultrastructure*; D051379:Mice; D008855:Microscopy, Electron, Scanning; D014566:Urogenital System / Q000196:embryology*