Henoch-Schönlein syndrome and selective IgA deficiency.
A 9 year old girl presented with clinical manifestations of Henoch-Schönlein syndrome and macroscopic haematuria. Laboratory investigations showed selective IgA deficiency and renal biopsy showed mesangial proliferative glomerulonephritis with diffuse granular deposits of C3 on immunofluorescence. IgA deposits were absent.
D002648:Child; D003176:Complement C3 / Q000032:analysis; D004406:Dysgammaglobulinemia / Q000150:complications*; D005260:Female; D005921:Glomerulonephritis / Q000150:complications; D006801:Humans; D017098:IgA Deficiency; D011695:IgA Vasculitis / Q000150:complications* / Q000276:immunology; D013290:Streptococcal Infections / Q000150:complications
D003176:Complement C3