title: Epidemiological studies on the prevalence of hepatitis Delta virus infections in the Federal Republic of Germany.
abstract: This study evaluated the prevalence of hepatitis Delta virus (HDV) infections in various groups of HBsAg carriers including drug addicts and patients with hemophilia in the Federal Republic of Germany. HDV was found only occasionally (less than 1%) in individuals found HBsAg positive during an examination as potential blood donors or in hemodialysis patients, but in 3% in patients with chronic hepatitis and up to 50% in drug addicts and hemophilia patients. These findings are in agreement with data reported from other European countries. Presence of antibodies to HDV in two hemodialysis patients indicates the presence of HDV in this group and screening for HDV infections in hemodialysis units is indicated to prevent outbreaks of this disease in HBsAg-positive patients with possibly serious consequences.
mesh_terms: D001782:Blood Donors; D005860:Germany, West; D006467:Hemophilia A / Q000276:immunology; D006509:Hepatitis B / Q000276:immunology; D006511:Hepatitis B Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D003699:Hepatitis D / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D035923:Hepatitis delta Antigens; D006801:Humans; D006435:Renal Dialysis; D019966:Substance-Related Disorders / Q000276:immunology
chemical_list: D006511:Hepatitis B Antigens; D006514:Hepatitis B Surface Antigens; D035923:Hepatitis delta Antigens; C442244:hepatitis delta virus large antigen