The interrelationship between SCE induction, cell survival, mutagenesis, aberration formation and DNA synthesis inhibition in V79 cells treated with N-methyl-N-nitrosourea or N-methyl-N'-nitro-N-nitrosoguanidine.
D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects*; D002869:Chromosome Aberrations; D006224:Cricetinae; D004247:DNA / Q000096:biosynthesis; D004260:DNA Repair / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008769:Methylnitronitrosoguanidine / Q000633:toxicity*; D008770:Methylnitrosourea / Q000633:toxicity*; D009154:Mutation / Q000187:drug effects*; D009607:Nitrosourea Compounds / Q000633:toxicity*; D012854:Sister Chromatid Exchange / Q000187:drug effects*
D009607:Nitrosourea Compounds; D008769:Methylnitronitrosoguanidine; D008770:Methylnitrosourea; D004247:DNA