title: Fetal alcohol syndrome: an examination of craniofacial dysmorphology in Macaca nemestrina.
abstract: The purpose of this investigation was to evaluate the craniofacial features in nonhuman primate models exposed in utero to moderate and high weekly binge doses of ethanol. While the high-dosed animal did have unusual craniofacial dysmorphology, she did not exhibit the typical facial pattern seen in human fetal alcohol syndrome. The high-dosed specimen displayed a scaphocephalic head shape secondary to synostosis of the sagittal suture. The brain of this monkey was grossly abnormal and microcephalic.
mesh_terms: D000818:Animals; D002508:Cephalometry; D005145:Face / Q000002:abnormalities*; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000473:pathology*; D006801:Humans; D008254:Macaca nemestrina; D051379:Mice; D011247:Pregnancy; D012886:Skull / Q000002:abnormalities*