Fetal alcohol syndrome: an examination of craniofacial dysmorphology in Macaca nemestrina.
The purpose of this investigation was to evaluate the craniofacial features in nonhuman primate models exposed in utero to moderate and high weekly binge doses of ethanol. While the high-dosed animal did have unusual craniofacial dysmorphology, she did not exhibit the typical facial pattern seen in human fetal alcohol syndrome. The high-dosed specimen displayed a scaphocephalic head shape secondary to synostosis of the sagittal suture. The brain of this monkey was grossly abnormal and microcephalic.
D000818:Animals; D002508:Cephalometry; D005145:Face / Q000002:abnormalities*; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000473:pathology*; D006801:Humans; D008254:Macaca nemestrina; D051379:Mice; D011247:Pregnancy; D012886:Skull / Q000002:abnormalities*