Atypical presentations of pyridoxine-dependent seizures: a treatable cause of intractable epilepsy in infants.
We report on 3 patients with atypical pyridoxine-dependent seizures. Each had either late onset of convulsions (2 cases) or seizure-free intervals of up to several months' duration in the absence of pyridoxine supplementation. The findings, taken together with those in 9 previously reported cases, indicate that a trial of pyridoxine should be performed in all seizure disorders with onset before 18 months of age, regardless of type.
D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011736:Pyridoxine / Q000008:administration & dosage / Q000627:therapeutic use*; D013226:Status Epilepticus / Q000188:drug therapy
D011736:Pyridoxine