title: Optic neuritis during lactation.
abstract: The condition called "lactation optic neuritis" has been previously considered a clinical entity of its own. Four women, who developed optic neuritis within 1-12 months while breast-feeding their infants, were investigated ophthalmologically and neurologically in order, to find specific clinical features for this condition. The course of the disorder was similar to classic optic neuritis without lactation. The clinical history and laboratory findings in three of the four patients suggested a demyelinating disorder. It is possible that the decreased immunosuppressive activity just after pregnancy induces the manifestation of an underlying demyelinating disease. The existence of "lactation optic neuritis," however, is questioned as a separate entity of its own. Lactation together with decreased immunosuppression may merely act as a provocateur in the onset of optic neuritis, which in many cases is the first clinical manifestation of incipient multiple sclerosis.
mesh_terms: D000328:Adult; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D007774:Lactation; D009902:Optic Neuritis / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D011241:Prednisone / Q000627:therapeutic use; D011247:Pregnancy; D014792:Visual Acuity
chemical_list: D011241:Prednisone