Action of prostaglandins on the dynamics of the aqueous humor.
Prostaglandins exercise different actions on the structures of the eye; among these is ocular hypertension. The mechanism by which ocular hypertension is provoked seems to be the breaking of the hematoaqueous barrier at the level of the iris and the ciliary processes. By fluorophotometry we studied the dynamics of the aqueous humor after topical administration of prostaglandin E-2 in rats. We observed an important reduction in flow that was interpreted as secondary to the increase in output resistance.
D000818:Animals; D001082:Aqueous Humor / Q000187:drug effects* / Q000378:metabolism; D019793:Fluorescein; D005452:Fluoresceins; D005453:Fluorescence; D011458:Prostaglandins E / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
D005452:Fluoresceins; D011458:Prostaglandins E; D019793:Fluorescein