Squamous-cell carcinoma of the anus. A follow-up study of 65 patients.
The five-year survival rate in 72 patients who underwent treatment for squamous-cell carcinoma of the anus in Stockholm County (1972 to 1978) has been studied. There were no differences in survival rates after rectum-preserving treatment (mainly consisting of irradiation +/- cytostatics +/- local excision) as compared with extensive surgery (abdominoperineal resection), even if the tumor size, location, and differentiation were taken into consideration. It therefore seems appropriate to suggest irradiation +/- cytostatics as the therapy of choice regardless of size, location, and differentiation of the tumor.
D000328:Adult; D000368:Aged; D001005:Anus Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012007:Rectum / Q000601:surgery