Iohexol and metrizamide for urography in infants and children.
The new nonionic contrast medium iohexol, was compared with metrizamide in a double blind investigation. Urography was performed in 40 children below 6 years of age. Adverse reactions were negligible. A small decrease in erythrocyte volume fraction (hematocrit) values after the injection was found in both groups. Excellent films were obtained in most patients and no difference in diagnostic quality between the two media was observed.
D002675:Child, Preschool; D003287:Contrast Media / Q000009:adverse effects; D004311:Double-Blind Method; D006400:Hematocrit; D006801:Humans; D007223:Infant; D007463:Iodobenzoates; D007472:Iohexol; D008793:Metrizamide / Q000009:adverse effects; D011897:Random Allocation; D014283:Triiodobenzoic Acids / Q000009:adverse effects; D014567:Urography
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol; D008793:Metrizamide