The association of hypertension, the Ask-Upmark kidney and other congenital abnormalities.
We report 2 cases of hypertension with segmental renal hypoplasia (Ask-Upmark kidney) and other anomalies in the absence of vesicoureteral reflux. These cases support the view that the Ask-Upmark kidney is a defect of renal development rather than acquired as a consequence of vesicoureteral reflux. In 1 patient the abnormal renal vein renin ratio suggested that the renin-angiotensin system may have had a part in the pathogenesis of the hypertension.
D000015:Abnormalities, Multiple; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D006974:Hypertension, Malignant / Q000209:etiology*; D006977:Hypertension, Renal / Q000209:etiology*; D007668:Kidney / Q000002:abnormalities* / Q000473:pathology