[Modification of the action of ionizing radiation on cells of transplantable tumors by administering xanthobine].
In experiments on mice it was established that the radiosensitizing effect of xanthobin was manifested by the enhancement of the inhibiting action of ionizing radiation on the growth of adenocarcinoma RL-67, diminution of the "shoulder" of the survival curve of Ehrlich ascites tumor cells, and increase in the average life of tumor-bearing animals.
D000230:Adenocarcinoma / Q000188:drug therapy / Q000532:radiotherapy; D000818:Animals; D002110:Caffeine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy / Q000532:radiotherapy; D003131:Combined Modality Therapy; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000532:radiotherapy*; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use*
D011838:Radiation-Sensitizing Agents; C017795:xanthobine; D002110:Caffeine
Modifikatsiia deĭstviia ioniziruiushche radiatsii na kletki perevivaemykh opukhole pri vvedenii ksantobina.