title: [Protein-synthesizing function of the liver of rabbits in experimental myocardial infarct].
abstract: The content of serum albumin in rabbit blood was found to be lowered within the first day after reproduction of experimental myocardial infarction. The rate and the level of translation of endogenous mRNA were studied in cell-free systems from normal rabbit liver and 6-12-24 h after experimental myocardial infarction. The decrease of the total protein synthesis in the crude cell-free system from the liver of experimental animals was shown to depend on the lack of energy supply rather than on the reduced activity of the protein-synthesizing apparatus. The relative drop of protein synthesis in the cell-free system with saturating concentration of ATP, GTP and creatine phosphate is likely to be connected with a decrease in the proportion of membrane-bound polysomes.
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D002474:Cell-Free System; D008099:Liver / Q000378:metabolism*; D009203:Myocardial Infarction / Q000378:metabolism*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D011817:Rabbits; D012709:Serum Albumin / Q000032:analysis; D013997:Time Factors
chemical_list: D001798:Blood Proteins; D012333:RNA, Messenger; D012709:Serum Albumin
vernacular_title: Beloksinteziruiushchaia funktsiia pecheni krolikov pri éksperimental'nom infarkte miokarda.