title: [Recurrence of myocardial infarct after discontinued administration of oral anticoagulants: fatal rebound for certain risk groups?].
abstract: Four cases of myocardial infarction after termination of anticoagulant therapy are presented. The controversy on the clinical relevance of the "rebound-phenomenon" is discussed: although laboratory parameters seem to suggest a rebound, the phenomenon may be of clinical importance only in certain subpopulations at risk. In these patients withdrawal of the anticoagulant therapy should be gradual.
mesh_terms: D000074:Acenocoumarol / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D003327:Coronary Disease / Q000188:drug therapy* / Q000503:physiopathology; D004334:Drug Administration Schedule; D005260:Female; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000503:physiopathology; D012008:Recurrence; D012306:Risk
chemical_list: D000074:Acenocoumarol
vernacular_title: Myokardinfarktrezidiv nach Absetzen der oralen Antikoagulation: fataler Rebound für bestimmte Risikogruppen?