title: Radiologic study of 42 cases of Wilson disease.
abstract: This paper reports 42 cases of bone and joint radiographic changes in hepatolenticular degeneration. The cases were proven clinically by ophthalmologic and laboratory study, and their radiographic and joint changes were divided into five groups: no abnormal findings, osteoporosis, osteomalacia (rickets), distinct changes, and miscellaneous. Distinct changes include marginal bone fragments, angulation of carpal bones, squaring of metacarpal heads, and calcification of the joint capsule or tendon insertion. The mechanism causing the bone changes in hepatolenticular degeneration is also discussed.
mesh_terms: D000293:Adolescent; D000328:Adult; D002114:Calcinosis / Q000000981:diagnostic imaging; D002648:Child; D005260:Female; D005264:Femoral Fractures / Q000000981:diagnostic imaging; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging; D006225:Hand / Q000000981:diagnostic imaging; D006527:Hepatolenticular Degeneration / Q000000981:diagnostic imaging*; D006621:Hip Joint / Q000000981:diagnostic imaging; D006801:Humans; D007592:Joint Diseases / Q000000981:diagnostic imaging; D007738:Kyphosis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010007:Osteochondritis / Q000000981:diagnostic imaging; D010024:Osteoporosis / Q000000981:diagnostic imaging; D011859:Radiography; D012279:Rickets / Q000000981:diagnostic imaging; D014955:Wrist Joint / Q000000981:diagnostic imaging