[Effect of prolonged restriction of overall motor activity on the hemomicrocirculatory bed of the retina of the rabbit].
In 56 rabbits kept in tight cages for 4, 8, 12, 16 and 20 weeks, effect of hypokinesia on structure of hemomicrocirculatory bed of the retina has been studied. The retina is digested in tripsin and then it is exfoliated, and the vessels are stained after Shiff. Diameters of arterioles, capillaries and venules are measured, their relations to each other and number of vessels per square unit are taken into consideration. Restriction of the motor activity for 4 weeks results in narrowing of arterioles, capillaries and venules, in increasing venuloarteriolar coefficient, in decreasing number of vessels per square unit, as compared to the norm. In 8 weeks of hypokinesia the diameter of all links of the hemomicrocirculatory bed is evenly increasing, but it does not reach the normal value; the number of the vessels is keeping to decrease; the venuloarteriolar coefficient is at the same level. In 12, 16 and 20 weeks changes in the diameter and the number of the vessels are poorly pronounced, have a wavy character and diversily directed. The value of the venuloarteriolar coefficient is kept constant. As a whole, the data obtained demonstrate that at a long hypokinesia the animals adapt to the new conditions of existence, and the state of the reticular hemomicrocirculatory bed stabilizes.
D000222:Adaptation, Physiological; D000818:Animals; D008297:Male; D011817:Rabbits; D012146:Rest; D012149:Restraint, Physical; D012171:Retinal Vessels / Q000033:anatomy & histology*
Vliianie dlitel'nogo ogranicheniia obshcheĭ dvigatel'noĭ aktivnosti na gemomikrotsirkuliatornoe ruslo setchatki glaza krolika.