The influence of contrast media on serum osmolality, haematocrit and cardiac output. A comparative study in dogs.
Thirty-two mongrel dogs were used in a comparative study to assess the effect of normal saline solution, metrizamide and Cardioconray on serum osmolality, haematocrit and cardiac output. The study demonstrated that the higher the osmolality of the test substance, the greater the reduction in haematocrit and the higher the increase in cardiac output.
D000818:Animals; D001769:Blood; D002302:Cardiac Output / Q000187:drug effects*; D003287:Contrast Media / Q000494:pharmacology*; D004285:Dogs; D006400:Hematocrit; D007482:Iothalamate Meglumine / Q000494:pharmacology; D007483:Iothalamic Acid / Q000494:pharmacology; D008793:Metrizamide / Q000494:pharmacology; D009994:Osmolar Concentration; D012965:Sodium Chloride / Q000494:pharmacology; D013997:Time Factors
D003287:Contrast Media; D007483:Iothalamic Acid; D012965:Sodium Chloride; D008793:Metrizamide; D007482:Iothalamate Meglumine