title: Extracorporeal stone disintegration using chemical explosive pellets as an energy source of underwater shock waves.
abstract: Extracorporeal renal stone disintegration using a chemical explosive pellet (lead azide 10 mg.) as an energy source of underwater shock waves has been successfully performed in animals. The shock wave was observed by holographic interferometry. Shock wave generation was performed by a reflector whose configuration was part of a pseudoellipsoid. The explosions were conducted 10 to 100 times for each animal and the stone (extracted human renal calculus or model calculus of activated alumina) placed in the renal pelvis was disintegrated satisfactorily. Negative findings in explorative laparotomy and histological examination, except for minor bleeding in several tubular lumina of the kidney, indicated that the method was clinically applicable.
mesh_terms: D000818:Animals; D001386:Azides; D004285:Dogs; D005260:Female; D006696:Holography; D007368:Interferometry; D007669:Kidney Calculi / Q000628:therapy*; D007854:Lead; D008096:Lithotripsy / Q000379:methods*; D008297:Male
chemical_list: D001386:Azides; D007854:Lead; C037372:lead azide