[Energy balance trials with a diet rich in fats in the human].
The effects of two diets equal in protein content (12% of energy) but different in carbohydrates (80% of energy) or in fat (68% of energy) were studied in a changeover trial with 6 healthy young subjects. Each person was 2 weeks on each diet. Under the conditions of slight undernutrition and neutral temperature the balances of nitrogen, carbon and energy were assessed in 7-day collection periods, and according to 48-hour measurements of gaseous exchange (carbon-nitrogen balance method) by the procedures of indirect calorimetry. At isocaloric supply of metabolizable energy no differences were found in the retention of N, C and energy. The heat production calculated by indirect calorimetry was not significantly different with both diets. The lower body weight during the high-fat diet was due to higher sodium and water excretion. The high-fat diet resulted in lower fecal and higher urine excretion of nitrogen, but because of a compensative response no difference in nitrogen retention was observed between the two dietary regimens. The plasma concentrations of cholesterol, glucose and uric acid were higher with fat-rich diet; those of triglycerides were higher with carbohydrate-rich diet. The results demonstrate that the composition of the diet did not influence the energy balance.
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001833:Body Temperature Regulation; D001835:Body Weight; D002153:Calorimetry, Indirect; D002784:Cholesterol / Q000097:blood; D004040:Dietary Carbohydrates / Q000008:administration & dosage / Q000378:metabolism; D004041:Dietary Fats / Q000008:administration & dosage* / Q000378:metabolism; D004044:Dietary Proteins / Q000008:administration & dosage; D004734:Energy Metabolism; D005260:Female; D006706:Homeostasis; D006801:Humans; D008297:Male; D009584:Nitrogen / Q000378:metabolism; D014280:Triglycerides / Q000097:blood; D014882:Water-Electrolyte Balance
D001786:Blood Glucose; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D014280:Triglycerides; D002784:Cholesterol; D009584:Nitrogen
Energiebilanzversuche mit fettreicher Diät beim Menschen.