title: Pseudomembranous colitis in children and adults.
abstract: Pseudomembranous colitis remains a potentially lethal complication of antibiotic usage. Identification of Clostridium difficile as the major pathogen has led to a rational successful approach to therapy and has widened the spectrum of associated disease. The frequent asymptomatic colonization of healthy neonates by C. difficile remains an enigma.
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001426:Bacterial Proteins; D001427:Bacterial Toxins / Q000378:metabolism; D002648:Child; D003013:Clostridium / Q000302:isolation & purification; D003106:Colon / Q000473:pathology; D004761:Enterocolitis, Pseudomembranous / Q000473:pathology* / Q000628:therapy; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D011379:Prognosis
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001427:Bacterial Toxins; C031815:toxB protein, Clostridium difficile