title: Squamous cell carcinoma in congenital ichthyosis with deafness and keratitis. A case report and review of the literature.
abstract: The first case of invasive squamous cell carcinoma (SCC) arising in the skin of a patient afflicted with keratitis, ichthyosis, and deafness (KID) syndrome is reported. A 35-year-old man, diagnosed as having KID syndrome in early childhood, developed bilateral fungating lesions on his feet. The entire left foot became involved with a multinodular fungating mass which proved to harbor a SCC, necessitating a left below-knee amputation. Although rare, KID syndrome can be associated with SCC of the skin.
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology; D003638:Deafness / Q000151:congenital*; D006801:Humans; D007057:Ichthyosis / Q000151:congenital*; D007634:Keratitis / Q000150:complications* / Q000473:pathology; D008297:Male; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology; D013577:Syndrome