[Effect of various methods of treating patients with the diabetic type of glucose tolerance].
A study of the frequency of "remissions" of disorders of the glucose tolerance test (GTT) of the diabetic type depending on therapy: diet and diet combined with sulfanilurea derivatives in 130 patients revealed the absence of significant dependence on the method of treatment of patients with a low level of glycemia following glucose load (below 11 and 8.25 mmol/l after 1 and 2 hours, respectively) and a significant rise of the frequency of the GTT return to normal (from 7% to 40%) with the use of sulfanilurea derivatives together with diabetic management from the moment of diagnosing the disease in patients with a higher level of glycemia in the process of the GTT (over 11 and 8.25 mmol/l 1 and 2 h, respectively after glucose load). On the other hand, in 38% of persons with the different GTT disturbances of the diabetic type receiving no therapy, with glycemia level after 1 hour up to 11 mmol/l and 8.25 mmol/l after 2 h, spontaneous GTT improvement can be observed in 3-6 years to come. To raise the frequency of remissions, the authors recommend differentiated treatment of patients with GTT of the diabetic type in the initial period of treatment depending on the glycemia level in the process of the GTT.
D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000097:blood / Q000628:therapy*; D003927:Diet, Diabetic; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006943:Hyperglycemia / Q000628:therapy*; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D011236:Prediabetic State / Q000097:blood / Q000628:therapy*; D013453:Sulfonylurea Compounds / Q000627:therapeutic use; D014044:Tolbutamide / Q000627:therapeutic use*
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; D014044:Tolbutamide
Effekt razlichnykh metodov lecheniia bol'nykh s diabeticheskim tipom tolerantnosti k gliukoze.