title: Effect of glucose and phloretin-2'-beta-D-glucose (phloridzin) on in vitro fertilization of mouse ova.
abstract: The fertilization ratio of mouse ova in vitro decreased when glucose concentration in the medium was lowered. However, the addition of phloretin-2'-beta-D-glucose (phloridzin), known as a glucose uptake inhibitor, restored the fertilization ratio back to the control level. The glucose moiety of the phloridzin seemed to be responsible for this effect.
mesh_terms: D000818:Animals; D005260:Female; D005307:Fertilization in Vitro / Q000187:drug effects*; D005947:Glucose / Q000494:pharmacology*; D051379:Mice; D010063:Ovum / Q000187:drug effects / Q000502:physiology*; D010695:Phlorhizin / Q000494:pharmacology*
chemical_list: D010695:Phlorhizin; D005947:Glucose