[Clinical and prognostic significance of determining the carcinoembryonic antigen in patients with gastrointestinal cancer].
The paper discusses the results of a radioimmunologic assay of carcinoembryonic antigen (CEA) levels in 100 cases of gastrointestinal cancer. CEA--PRIST kits (Phadebas, Sweden) and NGR-603 automatic gamma-unit (Tesla, Czechoslovakia) were employed. The test proved to be highly instrumental in the preoperative evaluation of prognosis and early detection of recurrence and metastasis. CEA concentrations within 30-50 ng/ml are highly suggestive of recurrence or metastases, whereas 50-100 ng/ml should serve an indicator of organ dissemination. The test is useful in assessing the effectiveness of treatment in the course of follow-up.
D000328:Adult; D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D011379:Prognosis; D011933:Reagent Kits, Diagnostic
D002272:Carcinoembryonic Antigen; D011933:Reagent Kits, Diagnostic
Klinicheskoe i prognosticheskoe znachenie opredeleniia rakovo-émbrional'nogo antigena u bol'nykh rakom zheludochno-kishechnogo trakta.