title: The dysequilibrium syndrome: a study of the etiology and pathogenesis.
abstract: The optimality of prenatal and perinatal conditions, serum levels of radioreceptor-assayable somatomedins and activity of catechol-0-methyltransferase in erythrocytes were examined in 13 dysequilibrium (DES) patients. No differences from normal controls were found. As a group, the DES patients were not more exposed to non-optimal prenatal and perinatal events than healthy controls. No association between DES and somatomedin levels or between DES and catechol-0-methyltransferase activity was demonstrated.
mesh_terms: D000293:Adolescent; D000328:Adult; D001259:Ataxia / Q000209:etiology; D002394:Catechol O-Methyltransferase / Q000097:blood*; D002547:Cerebral Palsy / Q000097:blood / Q000209:etiology*; D002648:Child; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000209:etiology; D008297:Male; D013002:Somatomedins / Q000097:blood*; D013577:Syndrome
chemical_list: D013002:Somatomedins; D002394:Catechol O-Methyltransferase