Influence of exfoliation syndrome on prognosis in ocular hypertension greater than or equal to 25 mm. A long-term follow-up.
Data on 144 patients who in 1969-1973 were found to have ocular hypertension greater than or equal to 25 mmHg without glaucomatous damage were collected retrospectively. Intraocular pressure-lowering treatment was prescribed with few exceptions. Thirteen out of 37 patients (35%) with exfoliation syndrome developed glaucomatous damage during the follow-up periods ranging from 5 to 14 years (mean 9.4 years). The corresponding result for patients without exfoliation syndrome was 20 out of 111 subjects (18%, mean follow-up 11.7 years, range 5-15 years). Low average intraocular pressure during the follow-up seemed to prevent the eyes from developing glaucomatous damage. This was especially evident for eyes with the exfoliation syndrome. The long-term effect of medical therapy on the pressure level of hypertensive eyes was often negligible.
D000368:Aged; D005128:Eye Diseases / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000209:etiology*; D006801:Humans; D007908:Lens, Crystalline / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011379:Prognosis; D012189:Retrospective Studies; D013577:Syndrome; D014794:Visual Fields