Cytogenetic findings in a case of Sézary syndrome.
Repeated cytogenetic studies were carried out on a Sézary syndrome patient during a 1-year period. The presence of a single clone of heteroploid (60-86 chromosomes) cells was a permanent finding in the PHA-stimulated blood cultures. The bone marrow was normal. Sister chromatid exchange (SCE) value was relatively lower in heteroploid cells.
D000368:Aged; D001853:Bone Marrow / Q000648:ultrastructure; D002871:Chromosome Banding; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D011003:Ploidies; D012008:Recurrence; D012751:Sezary Syndrome / Q000097:blood / Q000235:genetics*; D012854:Sister Chromatid Exchange