A macromolecular shape function based on sedimentation velocity parameters.
A volume-independent shape function, experimentally determinable from sedimentation velocity experiments, was formulated explicitly in terms of the axial ratio of a macromolecule considered as an ellipsoid of revolution. Use of this function offers a simple first approach to the elucidation of macromolecular geometry as illustrated by calculations for ovalbumin, bovine serum albumin, and myosin.
D002498:Centrifugation; D007700:Kinetics; D046911:Macromolecular Substances; D008433:Mathematics; D008956:Models, Chemical; D008970:Molecular Weight; D009218:Myosins; D010047:Ovalbumin; D011506:Proteins; D012710:Serum Albumin, Bovine; D014867:Water
D046911:Macromolecular Substances; D011506:Proteins; D014867:Water; D012710:Serum Albumin, Bovine; D010047:Ovalbumin; D009218:Myosins