A comparison of nerve cell loss in cortical and subcortical structures in Alzheimer's disease.
Loss of nerve cells from temporal cortex, hippocampus, nucleus basalis of Meynert and locus caeruleus was measured in 32 patients with Alzheimer's disease ranging from 48 to 92 years of age. Similar changes were present within the cerebral cortex and within the two subcortical structures.
D000368:Aged; D000544:Alzheimer Disease / Q000473:pathology*; D001921:Brain / Q000473:pathology*; D002452:Cell Count; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D008125:Locus Coeruleus / Q000473:pathology; D008875:Middle Aged; D013377:Substantia Innominata / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology