Management of uric acid renal obstruction by intravenous lactate.
6 patients presenting with uric acid renal obstruction were managed by alkalization of urine using intravenous perfusion of 0.16 (1/6) M sodium lactate. Despite obstructive renal failure in 3 patients, rapid relief of obstruction was obtained and surgery was not necessary in any patient. Lysis of uric acid stones by urine alkalization is well documented [1, 4-12]. Intravenous infusion of 0.16 (1/6) M sodium lactate provides rapid urinary alkalization and is effective in the relief of obstruction by dissolution of uric acid calculi.
D000328:Adult; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007669:Kidney Calculi / Q000378:metabolism / Q000628:therapy*; D007773:Lactates / Q000627:therapeutic use*; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D014527:Uric Acid / Q000378:metabolism*
D007773:Lactates; D014527:Uric Acid; D019344:Lactic Acid