[Renewal of hematopoietic stem cell clones in long-term bone marrow cultures].
In long-term cultures of murine bone marrow, clonal succession of hemopoietic cells was observed as measured by karyologic analysis. There were high oscillations in self-renewal of CFUs in the cultures. A close correlation between the CFUmix karyotype and mitotic non-adherent cells in culture (but not between these cell types and CFUs) was revealed.
D000818:Animals; D005260:Female; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D066298:In Vitro Techniques; D007621:Karyotyping; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D013997:Time Factors
Smena klonov krovetvornykh kletok v dlitel'nykh kul'turakh kostnogo mozga.