Yersinia enterocolitica infection complicated by severe thrombocytopenia resistant to high-dose intravenous immunoglobulin.
A young female patient developed severe thrombocytopenia 10 days after an infection with Yersinia enterocolitica, serotype 3. She was treated with high-dose intravenous immunoglobulin without effect, and later corticosteroids also failed to induce remission. After 10 days of profuse bleeding the platelet count rose slowly to normal. Her tissue type was HLA-B27. To our knowledge, thrombocytopenia complicating Yersinia infection has not been reported before.
D000293:Adolescent; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D011241:Prednisone / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D015009:Yersinia Infections / Q000150:complications* / Q000276:immunology / Q000628:therapy; D015008:Yersinia enterocolitica / Q000302:isolation & purification
D011241:Prednisone