[Peroxidation of blood serum lipids in rabbits with various thyroid functions].
Chemiluminescent properties of blood serum from rabbits with hypo-, normo- and hyperthyroidism were investigated. The ferrum-induced chemiluminescence of the serum was shown to be decreased both in hypo- and in hyperthyroidism as compared with the normal state. The oxidative capacity of the main substrate of the peroxidation in blood serum--apo-B containing lipoproteins--did not markedly differ in various states of thyroid gland. The efficiency of branched free radical chains was dissimilar; these data suggest that the content of lipid-soluble antioxidants was increased in the lipoproteins in hypo- and decreased in hyperthyroidism. Measuring of the chemiluminescence quenching in the standard chemiluminescent system indicated that the content of water-soluble antioxidants was increased in blood of animals both with hypo- and hyperthyroidism. However, a higher content of water-soluble antioxidants was noted in blood of rabbits with hypothyroidism as compared with the animals with hyperthyroidism.
D000818:Animals; D001055:Apolipoproteins B / Q000097:blood; D006980:Hyperthyroidism / Q000097:blood; D007037:Hypothyroidism / Q000097:blood; D007501:Iron / Q000494:pharmacology; D008054:Lipid Peroxides / Q000097:blood*; D008163:Luminescent Measurements; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D010084:Oxidation-Reduction / Q000187:drug effects; D011817:Rabbits; D013961:Thyroid Gland / Q000502:physiology*
D001055:Apolipoproteins B; D008054:Lipid Peroxides; D008315:Malondialdehyde; D007501:Iron
Perekisnoe okislenie lipidov syvorotki krovi krolikov s razlichnym tireoidnym sostoianiem.