[High-molecular antigenic complex of the pneumococcus: its properties].
The study of an antigenic preparation isolated from pneumococci, serotype 3, by the method of alkaline hydrolysis has revealed that the preparation contains a high-molecular complex protein-polysaccharide composition of the cell wall of this microorganism. The preparation contains at least two immunologically active components: the type-specific polysaccharide of serotype 3 pneumococcus and a nonspecific protein component. This antigenic preparation is capable of the formation of immunological memory in mice and protecting them from experimental challenge with pneumococci of homologous and heterologous serotypes.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000942:Antigens, Bacterial / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification*; D001428:Bacterial Vaccines / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification; D002473:Cell Wall / Q000276:immunology; D007114:Immunization; D007120:Immunochemistry; D051379:Mice; D008970:Molecular Weight; D011008:Pneumococcal Infections / Q000276:immunology / Q000517:prevention & control; D011135:Polysaccharides, Bacterial / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000276:immunology*
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D011135:Polysaccharides, Bacterial
Vysokomolekuliarnyĭ antigennyĭ kompleks pnevmokokka; nekotoyre svoĭstva.