Plasma levels of amitriptyline: effect of age and sex.
Routine doses of amitriptyline were given to 110 inpatients who were examined for clinical predictors of variability in steady-state total tricyclic antidepressant plasma levels. Increasing age (p less than .01) and female sex (p less than .05) were associated with higher plasma levels.
D000328:Adult; D000367:Age Factors; D000368:Aged; D000639:Amitriptyline / Q000008:administration & dosage / Q000097:blood* / Q000378:metabolism; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy; D004334:Drug Administration Schedule; D005260:Female; D006760:Hospitalization; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D009661:Nortriptyline / Q000097:blood; D012737:Sex Factors
D000639:Amitriptyline; D009661:Nortriptyline