Development of antral gastrin-like immunoreactivity and pituitary CCK8/gastrin-like immunoreactivity in rats.
Gel filtration of antral extract of adult rats revealed gastrin-17 and gastrin-34. Gel filtration of anterior pituitary extract showed CCK8 and gastrin-17, whereas posterior pituitary extract showed only a CCK8. Antral gastrin-like immunoreactivity (G-LI) increased after milk feeding and especially after weaning was started. Changes in diet may exert a profound influence on the ontogenic development of antral G-LI, but not pituitary CCK8/G-LI.
D000367:Age Factors; D000818:Animals; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism*; D005755:Gastrins / Q000276:immunology / Q000378:metabolism*; D010902:Pituitary Gland / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D011247:Pregnancy; D011863:Radioimmunoassay; D051381:Rats; D012844:Sincalide / Q000378:metabolism*; D013270:Stomach / Q000196:embryology / Q000254:growth & development
D005755:Gastrins; D012844:Sincalide