Hypertensive mechanisms: the role of altered smooth muscle and membrane function in the etiology of hypertension.
The etiology of essential hypertension has been under intensive investigation for a number of years, and the availability of a number of rat models of this disease has aided our understanding of the relationship between abnormalities in cardiovascular regulatory function and hypertension. It is accepted that abnormalities at a number of levels of these regulatory processes could be the basis of the pathological process; however, the cause-effect relationship has not always been clearly established. This introduction addresses the potential relationship between a number of parameters and the control of blood pressure, and the Symposium attempts to relate altered smooth muscle and membrane function to hypertension.
D002462:Cell Membrane / Q000502:physiology*; D002463:Cell Membrane Permeability; D006321:Heart / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000235:genetics / Q000503:physiopathology; D008954:Models, Biological; D009131:Muscle, Smooth, Vascular / Q000503:physiopathology*