[Problem of screening of antineoplastic drugs in tissue and cell cultures].
Problems on the anticancer drugs' screening in vitro are reviewed on the basis of generalized data from literature. The probability to screen in vitro the active substances is not less than the chance to screen the drugs active against the human tumours in experiments on animals. The use of special test-systems permits screening specific substances including those inducing the tumour cell differentiation.
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy; D002478:Cells, Cultured; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008223:Lymphoma / Q000188:drug therapy; D051379:Mice; D009374:Neoplasms, Experimental / Q000188:drug therapy; D010051:Ovarian Neoplasms / Q000188:drug therapy; D010190:Pancreatic Neoplasms / Q000188:drug therapy; D012513:Sarcoma, Experimental / Q000188:drug therapy
D000970:Antineoplastic Agents
Problemy otbora protivoopukholevykh veshchestv v tkanevykh i kletochnykh kul'turakh.