Analysis of neuroblastoma cell proteins using two-dimensional electrophoresis.
Polypeptide patterns of nine neuroblastoma and thirteen other cell lines were analyzed by 2-D PAGE. Of 600 polypeptide spots scored one was present in all neuroblastoma cell lines and none of the other cell types analyzed. Three were markedly increased in intensity in neuroblastoma relative to other cell lines, and one was markedly decreased in neuroblastoma and melanoma. These data provide a basis for a more detailed analysis of the polypeptide pattern of neuroblastoma cells.
D002478:Cells, Cultured; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D009363:Neoplasm Proteins / Q000032:analysis*; D009369:Neoplasms / Q000378:metabolism; D009447:Neuroblastoma / Q000378:metabolism*; D010455:Peptides / Q000032:analysis*
D009363:Neoplasm Proteins; D010455:Peptides