[Structure of the binding center of the serotonin S2 receptor].
On the basis of literary data on the relative efficiency of interactions between different ligands and receptors the model of binding site of S2-serotonin receptor has been carried out. The binding site consists of anion centre and two donor acceptor groups, its topography satisfies the stereochemical requirements and phisico-chemical characteristics of receptor-ligand interaction for wide-range compounds.
D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000378:metabolism; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006801:Humans; D008024:Ligands; D008954:Models, Biological; D008968:Molecular Conformation; D011985:Receptors, Serotonin / Q000032:analysis / Q000378:metabolism*; D012701:Serotonin / Q000378:metabolism*; D013329:Structure-Activity Relationship
D008024:Ligands; D011985:Receptors, Serotonin; D012701:Serotonin
Struktura sviazyvaiushchego tsentra S2-retseptorov serotonina.