[Steroid hormone receptors in malignant mammary gland tumors in dogs].
The content of estrogen (ER) and progesteron receptors (PR) were studied as related to histological type, the degree of malignancy and growth rate of spontaneous canine mammary carcinomas. No correlation was found between the ER and PR amount, histological type and degree of malignancy. Inverse correlation was detected between ER and PR and the growth rate. These results correspond to those obtained for human mammary tumours. Therefore canine mammary carcinomas can be considered as an adequate model for experimental therapy of this type of tumours.
D000230:Adenocarcinoma / Q000032:analysis; D000232:Adenofibroma / Q000032:analysis; D000818:Animals; D003537:Cystadenoma / Q000032:analysis; D003600:Cytosol / Q000032:analysis*; D004285:Dogs; D005260:Female; D008325:Mammary Neoplasms, Experimental / Q000032:analysis* / Q000648:ultrastructure; D010212:Papilloma / Q000032:analysis; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D012513:Sarcoma, Experimental / Q000032:analysis
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
Retseptory steroidnykh gormonov v zlokachestvennykh opukholiakh molochnykh zhelez sobak.