Fanconi syndrome associated with a non-ossifying fibroma of bone.
A 20-year-old man presenting with osteomalacia was found to have the Fanconi syndrome, as evidenced by hypophosphatemia with hyperphosphaturia, glycosuria in the presence of normoglycemia, and generalized aminoaciduria. After removal of a non-ossifying fibroma of the left tibia, the renal tubular abnormalities promptly resolved with subsequent healing of the osteomalacia. A humoral factor released from the tumor may have caused the disorder in proximal renal tubular cell transport.
D000328:Adult; D001859:Bone Neoplasms / Q000097:blood / Q000150:complications* / Q000601:surgery; D005198:Fanconi Syndrome / Q000209:etiology*; D005350:Fibroma / Q000097:blood / Q000150:complications* / Q000601:surgery; D006801:Humans; D008297:Male; D010018:Osteomalacia / Q000209:etiology; D010710:Phosphates / Q000097:blood; D013977:Tibia / Q000601:surgery*
D010710:Phosphates