[The role of lipid components of microsomal membranes of hepatocytes of the central Asian turtle in the actualization of radiation injuries].
Phase changes in the content of biomembrane lipids and in the rate of their peroxidation were observed in liver microsomes of Testudo horsfieldi irradiated with a dose of 129.10(-1) C/kg. It is suggested that the decrease in the formation of peroxidation products of a diene series at the initial stage of radiation sickness are conditioned by the decrease in the activity of the key enzyme systems which regulate biosynthesis of polyunsaturated fatty acids, while the increase in the sphingomyelin level activates the lipid-dependent enzymes which repair the injured membranes.
D000818:Animals; D005227:Fatty Acids / Q000378:metabolism / Q000528:radiation effects; D007425:Intracellular Membranes / Q000378:metabolism / Q000528:radiation effects*; D008054:Lipid Peroxides / Q000378:metabolism / Q000528:radiation effects; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism* / Q000528:radiation effects; D008862:Microsomes, Liver / Q000378:metabolism / Q000528:radiation effects*; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D011836:Radiation Tolerance; D013997:Time Factors; D014426:Turtles
D005227:Fatty Acids; D008054:Lipid Peroxides; D008563:Membrane Lipids
Rol' lipidnykh komponentov mikrosomal'nykh membran gepatotsitov sredneaziatskoĭ cherepakhi v realizatsii luchevykh povrezhdeniĭ.