[Transplantation immunity to a UV-induced murine sarcoma by injection of a glycoprotein fraction from the tumor].
One single subcutaneous injection of 100 micrograms protein of a glycoprotein fraction from UV light-induced mouse sarcoma produces transplantation resistance against the same tumor. The glycoprotein fraction was isolated by 2% Triton X-100 and 3M KCl from enriched membranes. As measured by immunogenicity a tenfold enrichment of a tumor-associated antigen was obtained when compared with the 3M KCl extract on the basis of protein concentration.
D000818:Animals; D000951:Antigens, Neoplasm / Q000276:immunology / Q000302:isolation & purification; D002462:Cell Membrane / Q000378:metabolism; D006023:Glycoproteins / Q000276:immunology / Q000302:isolation & purification; D006649:Histocompatibility Antigens / Q000276:immunology; D051379:Mice; D009363:Neoplasm Proteins / Q000276:immunology* / Q000302:isolation & purification; D009368:Neoplasm Transplantation; D009381:Neoplasms, Radiation-Induced / Q000276:immunology*; D012513:Sarcoma, Experimental / Q000276:immunology*
D000951:Antigens, Neoplasm; D006023:Glycoproteins; D006649:Histocompatibility Antigens; D009363:Neoplasm Proteins
Transplantationsimmunität gegen ein UV-Sarkom der Maus durch Injektion einer glykoproteinhaltigen Fraktion.