Schizophrenia and cerebral laterality.
Investigators have suggested that schizophrenic patients have reversals of abnormal structural abnormalities and abnormal left hemisphere function. The authors attempted to know of the pattern of cerebral asymmetry in schizophrenic patients and controls on the computerized tomography scans of thirty right-handed schizophrenic patients and thirty right-handed control subjects. Compared to thirty right-handed controls, the schizophrenic patients had a significantly increased frequency of frontal and occipital reversals. This result suggests that reversals of neuroanatomical asymmetries, and by implicating the abnormalities of lateralization, are relevant to some schizophrenics. Statistics were done by the Chi square method.
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging*; D005260:Female; D005625:Frontal Lobe / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D009778:Occipital Lobe / Q000000981:diagnostic imaging; D012559:Schizophrenia / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed