Cutaneous infection at dog bite wounds associated with fulminant DF-2 septicemia.
Severe DF-2 sepsis with disseminated intravascular coagulopathy developed following dog bites in two patients who had undergone prior splenectomy. Eschariform lesions developed at the site of the animal bite in both patients. DF-2 is an unusual animal-borne slow-growing gram-negative rod that can cause fulminant sepsis in splenectomized patients. Splenectomized patients should be aware of the hazards from a dog bite. The presence of eschariform lesions in such patients should provide a clinical clue to the presence of DF-2 infection.
D000328:Adult; D000818:Animals; D001424:Bacterial Infections / Q000209:etiology*; D001733:Bites and Stings / Q000150:complications*; D004285:Dogs; D005260:Female; D006090:Gram-Negative Bacteria; D006225:Hand; D006801:Humans; D018805:Sepsis / Q000209:etiology*; D013156:Splenectomy; D014946:Wound Infection / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology