Beneficial effects of fasting and low carbohydrate diet in D-lactic acidosis associated with short-bowel syndrome.
A case of D-lactic acidosis in an 18-yr-old man with a short bowel is reported. The diagnosis, suspected on clinical grounds, was confirmed by serum and urine levels of D-lactate. Our studies revealed that an ad libitum diet was associated with elevated D-lactate levels and "nothing per oral" and 10% carbohydrate diet regimens caused a drop in D-lactate levels. We recommend npo and low carbohydrate diet as preferred alternatives to antibiotics in some patients with D-lactic acidosis. The literature is reviewed.
D000138:Acidosis / Q000178:diet therapy* / Q000209:etiology; D000293:Adolescent; D004040:Dietary Carbohydrates / Q000008:administration & dosage* / Q000627:therapeutic use; D005215:Fasting; D006801:Humans; D007773:Lactates; D019344:Lactic Acid; D008286:Malabsorption Syndromes / Q000150:complications*; D008297:Male; D012778:Short Bowel Syndrome / Q000150:complications*
D004040:Dietary Carbohydrates; D007773:Lactates; D019344:Lactic Acid