[Effect of dopamine and its combination with furosemide on urination in the rat].
Subcutaneous injection of dopamine (0.2-0.5 mg/kg) increased the daily diuresis and excretion of sodium, potassium and creatinine. The raising of the dose to 1 mg/kg did not alter renal function, but the initial effect recurred when the alpha-adrenolytic phentolamine was administered simultaneously. Dopamine (0.4-0.5 mg/kg) potentiated the natriuretic action of furosemide apparently at the expense of more pronounced inhibition of tubular reabsorption of sodium.
D000818:Animals; D004231:Diuresis / Q000187:drug effects; D004298:Dopamine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005665:Furosemide / Q000494:pharmacology*; D009318:Natriuresis / Q000187:drug effects; D051381:Rats; D014554:Urination / Q000187:drug effects*
D005665:Furosemide; D004298:Dopamine
Vliianie dofamina i ego sochetaniia s furosemidom na mocheotdelenie u krys.