Dose-response analysis of combination preparations.
A parametric model for quantal response to combination preparations is defined and discussed. Tests for additivity of the combination preparation are specified and demonstrated by an example. Parallelism of the dose-response curves is not required.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004336:Drug Antagonism; D004338:Drug Combinations; D004357:Drug Synergism; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D008433:Mathematics; D008962:Models, Theoretical
D004338:Drug Combinations