[Effect of a high-frequency electrical current on the activity of the raphe nuclei and the locus coeruleus].
Recovery cycles of primary evoked potentials to light flashes in the visual cortical area of waking rats were studied under conditions of pharmacological and electrical influences on serotonin (5-HT)- and noradren (NA)ergic brain systems. All factors used induced oscillations of the recovery cycles. Periods of oscillations were similar (300-400 ms) during pharmacological suppression of the NA-system and during high-frequency (500 Hz) electrical stimulation or lesion of locus coeruleus. Analogous influences on 5-HT-system were accompanied by oscillations of recovery cycles with a period of 200 ms. Mechanism of inhibitory action of high-frequency electrical stimulation on activity of monoaminergic systems is discussed.
D000818:Animals; D001931:Brain Mapping; D004558:Electric Stimulation; D008125:Locus Coeruleus / Q000502:physiology*; D008297:Male; D009433:Neural Inhibition; D009434:Neural Pathways / Q000502:physiology; D009638:Norepinephrine / Q000502:physiology; D011903:Raphe Nuclei / Q000502:physiology*; D051381:Rats; D012701:Serotonin / Q000502:physiology; D014793:Visual Cortex / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*
D012701:Serotonin; D009638:Norepinephrine
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