[Localization of the adrenodoxin-binding fragment of cholesterol hydroxylating cytochrome P-450 from adrenal cortex mitochondria].
The interaction between cytochrome P-450scc and adrenodoxin has been studied using cleavable cross-linking reagents and limited trypsinolysis. The data obtained indicate that the site responsible for adrenodoxin binding is located on the NH2-terminal fragment F1 of cytochrome P-450scc.
D000302:Adrenal Cortex / Q000201:enzymology*; D000325:Adrenodoxin / Q000032:analysis*; D000818:Animals; D001665:Binding Sites; D003432:Cross-Linking Reagents; D003577:Cytochrome P-450 Enzyme System / Q000032:analysis*; D005287:Ferredoxin-NADP Reductase / Q000032:analysis*; D008928:Mitochondria / Q000201:enzymology*; D009247:NADH, NADPH Oxidoreductases / Q000032:analysis*
D003432:Cross-Linking Reagents; D000325:Adrenodoxin; D003577:Cytochrome P-450 Enzyme System; D005287:Ferredoxin-NADP Reductase; D009247:NADH, NADPH Oxidoreductases
Lokalizatsiia adrenodoksinsviazyvaiushchego fragmenta kholesteringidroksiliruiushchego tsitokhroma P-450 iz mitokhondriĭ kory nadpochechnikov.