Sinus histiocytosis with massive lymphadenopathy: skeletal involvement.
A 9-year-old girl with known sinus histiocytosis with massive lymphadenopathy (SHML) has been followed since infancy. At age six, she developed swelling and pain in several joints. Subsequently, bone lesions were identified by scintigraphy and radiographs. Biopsy of the bone showed typical features of SHML. Bone lesions in this disease are rare. The lesions in this patient were followed for 3 years and remained unchanged despite chemotherapy.
D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology; D002648:Child; D005121:Extremities / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications* / Q000473:pathology; D011859:Radiography