Anaphylactoid reaction to corticosteroid: case report and review of the literature.
It has been suggested that corticosteroids can cause allergic reactions including anaphylaxis. Thirty-five patients have been reported to have anaphylaxis-like reactions following exposure to hydrocortisone in topical and parenteral preparations. We describe a further case of a nonatopic woman who developed urticaria during intravenous infusion of hydrocortisone. A review of the literature reveals that IgE-mediated immediate hypersensitivity has not been definitely proven in any case. We conclude that the clinical manifestations occasionally experienced after receiving hydrocortisone are most likely pseudoallergic reactions.
D000707:Anaphylaxis / Q000139:chemically induced*; D004342:Drug Hypersensitivity / Q000209:etiology; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects*; D007270:Injections, Intra-Articular; D008875:Middle Aged
D006854:Hydrocortisone