L-155,175: a new antiparasitic macrolide. Fermentation, isolation and structure.
A new antiparasitic macrolide, L-155,175, produced by a strain of Streptomyces hygroscopicus, has been isolated; its structure was determined by physico-chemical means. It is active against the tapeworm Hymenolepis diminuta in rats.
D000981:Antiprotozoal Agents / Q000032:analysis / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002621:Chemistry; D003470:Culture Media / Q000032:analysis; D005285:Fermentation; D009682:Magnetic Resonance Spectroscopy; D012988:Soil Microbiology; D012997:Solvents; D013302:Streptomyces / Q000032:analysis / Q000378:metabolism; D013329:Structure-Activity Relationship
D000981:Antiprotozoal Agents; D003470:Culture Media; D012997:Solvents