Liver uptake of 99mTc-labeled diphosphonate (DPD) by metastatic lesions from large bowel carcinoma.
Accumulation of 99mTc-diphosphonate was observed in 2 of 12 patients with liver metastases who had primary adenocarcinoma of the large bowel. The area of excessive radionuclide concentration corresponded well to the location of the hepatic metastases. The literature on this subject is reviewed and a possible mechanism of radionuclide accumulation is discussed.
D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000556:secondary; D003110:Colonic Neoplasms / Q000473:pathology*; D004164:Diphosphonates; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D013667:Technetium
D004164:Diphosphonates; D015609:Organotechnetium Compounds; C033905:technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid; D013667:Technetium