Structure of two new oligosaccharides isolated from human milk: sialylated lacto-N-fucopentaoses I and II.
The structures of two minor oligosaccharides isolated from human milk have been investigated. By using f.a.b.-mass spectrometry, methylation analysis, and partial formolysis as the principal methods of structural investigation, these oligosaccharides were identified as IV2-alpha-Fuc-III6-alpha-NeuAc-LcOse4 and IV3-alpha-NeuAc-III4-alpha-Fuc-LcOse4. This latter oligosaccharide has been recently found to be the carbohydrate moiety of a ganglioside isolated from a colorectal carcinoma cell-line (see ref. 12).
D002854:Chromatography, Paper; D005260:Female; D006801:Humans; D013058:Mass Spectrometry; D008745:Methylation; D008895:Milk, Human / Q000032:analysis*; D009844:Oligosaccharides / Q000032:analysis*
D009844:Oligosaccharides