[Changes in the cathepsin activity of reticuloendothelial cells under the effect of biologically active substances].
The level of cathepsin D, an enzyme of the lysosomal origin was used as a criterion of the increase in the digestive capacity of macrophages under the action of biologically active substances. It was shown that the use of prodigiosan changed the enzyme activity in the cells of the peritoneal exudate and spleen of the albino mice. Increased activity of cathepsin D was considered as a state of increased readiness for phagocytosis.
D000818:Animals; D001202:Ascitic Fluid / Q000201:enzymology / Q000276:immunology; D002402:Cathepsin D / Q000378:metabolism*; D002417:Cattle; D004789:Enzyme Activation; D066298:In Vitro Techniques; D008247:Lysosomes / Q000201:enzymology; D008264:Macrophages / Q000201:enzymology / Q000276:immunology; D051379:Mice; D012157:Mononuclear Phagocyte System / Q000201:enzymology* / Q000276:immunology; D010587:Phagocytosis; D011354:Prodigiozan / Q000494:pharmacology; D013154:Spleen / Q000201:enzymology / Q000276:immunology; D014443:Tyrosine / Q000494:pharmacology; D015010:Yersinia pestis / Q000276:immunology; D015054:Zymosan / Q000494:pharmacology
D014443:Tyrosine; D015054:Zymosan; D011354:Prodigiozan; D002402:Cathepsin D
Izmenenie urovnia aktivnosti katepsina v kletkakh retikuloendotelial'noĭ sistemy pod vliianiem biologicheski aktivnykh veshchestv.