Effect of aloe lectin on deoxyribonucleic acid synthesis in baby hamster kidney cells.
A homogeneous glycoprotein (mol. wt 40,000) containing 34% carbohydrate was isolated from Aloe arborescens var. natalensis. At a concentration of 5 micrograms/ml, this glycoprotein was shown to stimulate deoxyribonucleic acid (DNA) synthesis in baby hamster kidney (BHK) cells and to have the properties of a lectin which reacts with sheep blood cells. The chemical and physical properties of the glycoprotein (aloe lectin) are also discussed.
D000504:Aloe / Q000032:analysis*; D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D004247:DNA / Q000096:biosynthesis*; D006023:Glycoproteins / Q000494:pharmacology; D006358:Hot Temperature; D007668:Kidney; D037102:Lectins / Q000494:pharmacology*; D037121:Plant Lectins; D010946:Plants, Medicinal / Q000032:analysis*; D014945:Wound Healing
D006023:Glycoproteins; D037102:Lectins; D037121:Plant Lectins; D004247:DNA