Incorporation routes of elements into human hair; implications for hair analysis used for monitoring.
A study has been made on the incorporation of some trace elements and minerals into human hair by measuring their distributions across hair diameters. For this study the Particle Induced X-ray Emission (PIXE) technique using the proton microbeam of the Vrije Universiteit of Amsterdam has been applied. Results of measurements on single hair strands at different positions in the root and outside the skin provide evidence that the elements not only can enter the cortex via the matrix but also via the hair root sheaths. Moreover, there are indications that the distribution of an endogenous element is not always homogeneously spread over a cross section of the hair. Endogenous Fe and Pb seem to be peaked on the periphery of the hair by natural means, while the elements S,Zn and Cu of the samples measured are found to be distributed homogeneously across the hair diameter. The consequences for hair analysis in use for monitoring the trace elements status of an individual are discussed.
D000328:Adult; D002118:Calcium / Q000032:analysis; D003300:Copper / Q000032:analysis; D004577:Electron Probe Microanalysis / Q000379:methods; D005260:Female; D006197:Hair / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000032:analysis; D008297:Male; D011188:Potassium / Q000032:analysis; D013455:Sulfur / Q000032:analysis; D014131:Trace Elements / Q000032:analysis* / Q000378:metabolism; D015032:Zinc / Q000032:analysis
D014131:Trace Elements; D013455:Sulfur; D003300:Copper; D007501:Iron; D015032:Zinc; D011188:Potassium; D002118:Calcium