[Comparative characteristics of the activity of lithium preparations and anti-arrhythmia agents in strophanthin, calcium chloride and barium chloride arrhythmias in an experiment].
During disorders of cardiac rhythm induced by strophanthine K in anesthesized cats, by calcium chloride in mice and anesthesized rats, and by barium chloride in rabbits, lithium hydroxybutyrate (0.55-3.2 mg/kg according to cation) compares very favourably with lithium chloride, novocainamide, lidocaine, trimecaine, etmozine, quinidine and verapamil as regards antiarrhythmic activity and the range of therapeutic action.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use* / Q000633:toxicity; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000188:drug therapy*; D001464:Barium / Q000494:pharmacology*; D017609:Barium Compounds; D002122:Calcium Chloride / Q000494:pharmacology*; D002415:Cats; D002712:Chlorides; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005260:Female; D007928:Lethal Dose 50; D008094:Lithium / Q000627:therapeutic use* / Q000633:toxicity; D008297:Male; D051379:Mice; D011817:Rabbits; D013328:Strophanthins / Q000494:pharmacology*
D000889:Anti-Arrhythmia Agents; D017609:Barium Compounds; D002712:Chlorides; D013328:Strophanthins; C024986:barium chloride; D001464:Barium; D008094:Lithium; D002122:Calcium Chloride
Sravnitel'naia kharakteristika aktivnosti preparatov litiia i antiaritmicheskikh sredstv pri strofantinovoĭ, khloridkal'tsievoĭ i khloridbarievoĭ aritmiiakh v éksperimente.