Rate sensitivity of blood pressure to hypoxia.
A biochemical kinetic model is used to describe changes in mean arterial blood pressure in dogs to three different rates of fall of arterial partial pressure of oxygen. The model is a linear loop with one variable rate coefficient (parametric control) which has been previously shown to characterize the rate sensitivity to presented stimuli. A three component model was identified under a least squares criterion and it showed that a unique (stimulation independent) representation can be obtained which can serve as a conceptual framework for the study of this phenomenon.
D000818:Animals; D001794:Blood Pressure; D004285:Dogs; D000860:Hypoxia / Q000503:physiopathology*; D008433:Mathematics; D008955:Models, Cardiovascular; D010100:Oxygen; D010313:Partial Pressure
D010100:Oxygen