[A fatal case of farmer's lung: a study of specific classes of antibodies in the serum and broncho-alveolar lavage].
A 61 year old agricultural worker, without any respiratory past history, presented with a pulmonary fibrosis of rapid and fatal outcome. This was due to an extrinsic allergic fibrosing alveolitis of the Farmer's lung type. A search for precipitins "vis-à-vis" Micropolyspora faeni was strongly positive in the serum and broncho-alveolar lavage. Specific IgA antibodies to M. faeni, as well as specific antigenic fractions of M. faeni were demonstrated in the broncho-alveolar lavage. This IgA was almost certainly produced locally.
D000907:Antibodies, Bacterial / Q000032:analysis* / Q000145:classification; D001980:Bronchi / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005122:Exudates and Transudates / Q000276:immunology; D005203:Farmer's Lung / Q000276:immunology* / Q000382:microbiology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007128:Immunoglobulin Fragments / Q000032:analysis; D008297:Male; D008848:Micromonosporaceae / Q000276:immunology*; D008875:Middle Aged; D007507:Therapeutic Irrigation
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007128:Immunoglobulin Fragments
Un cas mortel de maladie de poumon du fermier: étude des classes d'anticorps spécifiques dans le sérum et le lavage broncho-alvéolaire.