Membrane proteins and glycoproteins specific to central nervous system axons and growth cones.
The specific functions of axons with growth cones might be correlated with a specific molecular composition differing from that of the perikarya. Thus axons with growth cones and cell perikaryal fractions were isolated by microdissection from neural retina explants of 6-day-old chick embryos. The protein composition of the minute amount of material available was analyzed with a two-dimensional micro-gel electrophoresis system in combination with various labeling procedures for surface- and glycoproteins. All methods showed, besides common features, proteins specific for axons with growth cones and for cell bodies.
D000818:Animals; D001369:Axons / Q000032:analysis; D002642:Chick Embryo; D046508:Culture Techniques; D005136:Eye Proteins / Q000032:analysis*; D006023:Glycoproteins / Q000032:analysis*; D008565:Membrane Proteins / Q000032:analysis*; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009474:Neurons / Q000032:analysis; D012160:Retina / Q000032:analysis* / Q000196:embryology
D005136:Eye Proteins; D006023:Glycoproteins; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins