In vitro study of modifications of blood flow patterns induced by a bifurcation.
Velocity profiles obtained with atheromatous and normal bifurcation castings in the presence of various types of flows are proposed. In the atheromatous bifurcation, with steady flow, we observe radial positive or negative velocities at distance to the wall smaller than 1 mm, which may be attributed to small local eddy motions. The maximum of velocity needs a larger distance from the apex than in the case of the "normal" bifurcation to be again located on the axes. With periodical flows, the effects are strongly damped. The wall velocity gradients on several geometries of tubings are investigated to separate the effects of the local rugosity of the wall from those incidental to the geometry of the bifurcation. The alterations caused by the atheroma do not seem to be induced by local modifications or rugosity, but by slow modifications of the local diameter. As a consequence, the variations of the velocity gradient caused by atheroma in the total bifurcation, are more likely due to distance effects of the geometry itself than to local effects of rugosity.
D001161:Arteriosclerosis / Q000209:etiology* / Q000503:physiopathology; D001783:Blood Flow Velocity; D006801:Humans; D008955:Models, Cardiovascular; D012826:Silicone Elastomers; D013997:Time Factors
D012826:Silicone Elastomers