Histopathologic effect of preoperative chemotherapy using 5-Fu fat emulsion in gastric cancer.
The authors report histopathologic effect of preoperative chemotherapy using 5-Fu fat emulsion for a series of 42 cases of gastric carcinoma. To each patient 348-464 mg of 5-Fu emulsion was given orally every day for 10 days before operation. It was well tolerated and no apparent side-effects were encountered. The overall response rate was 57.14%. We hold that this regimen is beneficial for gastric cancer.
D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage*; D006801:Humans; D013274:Stomach Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*
D005472:Fluorouracil