[Changes in the leukocyte capacity for rosette formation as affected by actinolysate in actinomycosis patients and healthy donors].
The action of actinolysate on the capacity of lymphocytes and neutrophils for rosette-formation has been studied in patients with actinomycosis of the maxillofacial area and with chronic nonspecific inflammatory processes, as well as in healthy donors. Actinolysate has been found to have different influence on cell activity. In actinomycosis patients with the low capacity of cells for spontaneous E-rosette-formation with sheep red blood cells (SRBC) actinolysate suppresses their activity still greater, while in cases of the high capacity of cells for spontaneous epsilon-rosette-formation with SRBC this capacity is increased. In chronic nonspecific inflammatory processes in the maxillofacial area and in healthy donors the reverse tendency is observed.
D000190:Actinomyces / Q000276:immunology*; D000197:Actinomycosis, Cervicofacial / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial / Q000276:immunology*; D002908:Chronic Disease; D005145:Face; D006801:Humans; D007249:Inflammation / Q000276:immunology; D007571:Jaw Diseases / Q000276:immunology; D007962:Leukocytes / Q000187:drug effects / Q000276:immunology*; D008875:Middle Aged; D012397:Rosette Formation
D000942:Antigens, Bacterial
Izmenenie sposobnsoti leĭkotsitov k rozetkoobrazovaniiu pod vliianiemaktinolizata u bol'nykh aktinomikozom i zdorovykh donorov.