[Bilateral femur head necrosis following high dosage corticosteroid therapy for chorioretinitis].
The early development of bilateral osteonecrosis of the femoral head after high doses of steroids in two young patients suffering from chorioretinitis is described. Steroids were given orally and by parabulbar injections. Consecutive avascular necrosis of the femoral head was treated in both cases by flexion osteotomy combined with cancellous bone grafting of the lesion. In one case a pedunculate bone graft was inserted. Early treatment requires early diagnosis and a high index of suspicion in the affected patient, and seems crucial in respect to prognosis. Conventional X-rays of the affected hips, combined with skeletal scintigraphy in the early stage, appear to be simple and useful diagnostic tools.
D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use; D000328:Adult; D002825:Chorioretinitis / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005271:Femur Head Necrosis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D014605:Uveitis / Q000188:drug therapy
D000305:Adrenal Cortex Hormones
Bilaterale Femurkopfnekrose nach hochdosierter Corticosteroidtherapie wegen Chorioretinitis.