[Effect of carnitine on energy processes in the myocardium of rats].
Experiments on white male rats with novodrine-induced heart necrosis have shown that carnitine chloride increases the conjugation of respiration and phosphorylation in heart mitochondria of intact rats. The prophylactic and therapeutic application of the drug has a beneficial effect on energy formation in the myocardium. It is advisable to use carnitine for energodynamic heart insufficiency.
D000818:Animals; D002331:Carnitine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004734:Energy Metabolism / Q000187:drug effects*; D006321:Heart / Q000187:drug effects*; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D009336:Necrosis; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D013997:Time Factors
D007545:Isoproterenol; D002331:Carnitine
Vliianie karnitina na énergeticheskie protsessy v miokarde krys.