[Prediction of pulmonary hypertension from simple, noninvasive parameters using discriminant analysis].
Based on a large number of males with chronic obstructive bronchitis, the usefulness of discriminant analysis for prediction of pulmonary hypertension has been investigated. Two groups were formed: 227 men with overt pulmonary hypertension; 145 patients without pulmonary hypertension Applying the discriminant analysis, 9 variables were selected step by step; 6 out of them were measurably contributing to the discrimination of both groups. As relevant turned out diameter of the right descending pulmonary artery, FVC% predicted, FEV1% FVC, pa2, systolic blood pressure, and RV% TLC. In a procedure of reclassification, based upon the calculated discriminant functions, 82,6% of the cases were correctly classified (sensitivity 80,6%, specificity 86,2%). A pocket calculator programme following the method by Läuter gave identical results. The application of the discriminant function to a new group of 147 unselected men with chronic obstructive bronchitis corroborated the foregoing results. 79,1% of all patients with overt or latent pulmonary hyper-tension were detected. For overt hypertension the sensitivity was 88,4%, for latent hypertension 62,5%. Using this method, decision-making regarding heart catheterism can be improved. It must be stressed, however, that this discriminant function is not valid for women and for other diagnosis groups in males.
D001991:Bronchitis / Q000503:physiopathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000503:physiopathology*; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000503:physiopathology*; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000503:physiopathology; D011669:Pulmonary Wedge Pressure; D013223:Statistics as Topic; D014655:Vascular Resistance
Vorhersage der pulmonalen Hypertonie aus einfachen, nichtinvasiven Parametern unter Verwendung der Diskriminanzanalyse.