Structure and variation within variant surface glycoproteins of Trypanosoma brucei.
Variant surface glycoproteins of the African trypanosomes are members of a multigene family which show extraordinary amino sequence diversity. The extent of this diversity and the significance of homologies both in the amino acid sequence and in the post-translational modifications are discussed in the light of what is predicted for the structure of these molecules and what is now known from X-ray crystallographic analysis.
D000595:Amino Acid Sequence; D000818:Animals; D003461:Crystallography; D006023:Glycoproteins / Q000032:analysis*; D011499:Protein Processing, Post-Translational; D014346:Trypanosoma brucei brucei / Q000032:analysis*; D014643:Variant Surface Glycoproteins, Trypanosoma; D014961:X-Ray Diffraction
D006023:Glycoproteins; D014643:Variant Surface Glycoproteins, Trypanosoma