Evaluation of jackrabbits as nonruminant hosts for Anaplasma marginale.
Two black-tailed jackrabbits (Lepus californicus), 1 splenectomized and 1 intact, were inoculated with 0.2 ml of a 1:5 dilution of a Florida Anaplasma marginale stabilate. Five months later, both hares were inoculated with 1 ml of whole blood from a calf with acute anaplasmosis. Neither hare developed any signs of clinical anaplasmosis. Pooled blood (7 ml) from these jackrabbits which was inoculated into 2 Anaplasma-susceptible, splenectomized calves failed to induce hematologic or serologic signs of anaplasmosis for at least 90 days. Two susceptible, splenectomized calves were inoculated with 35 ml of pooled whole blood from 9 wild-collected black-tailed jackrabbits from a known anaplasmosis enzootic area. Both steers remained free of anaplasmosis signs for 90 days.
D000712:Anaplasmosis / Q000635:transmission; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000635:transmission; D004197:Disease Reservoirs / Q000662:veterinary*; D004198:Disease Susceptibility; D007793:Lagomorpha; D008297:Male; D008322:Mammals; D013154:Spleen / Q000276:immunology