[Effect of UV-irradiated donor blood on the colony-forming ability of human bone marrow cells in culture].
A possible mechanism of the hemopoiesis stimulation by UV and solar radiation was studied. The UV irradiation of leucocyte-enriched donor serum results in increasing the colony formation activity of the serum. The addition of such a serum but depleted of leucocytes to human bone marrow cells in semisolid agar culture stimulates its colony formation by 1.5-3 times. A serum depleted of leucocytes before the irradiation has not this property. It is supposed that cell surface glycoproteins, desorbing into the serum under UV irradiation, induce the colony formation activity of UV-irradiated blood.
D001769:Blood / Q000528:radiation effects*; D001782:Blood Donors; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D006410:Hematopoiesis / Q000528:radiation effects; D006801:Humans; D010949:Plasma / Q000528:radiation effects; D014466:Ultraviolet Rays
Vliianie UF-obluchennoĭ donorskoĭ krovi na kolonieobrazuiushchuiu sposobnost' kletok kostnogo mozga cheolveka v kul'ture.