Mesangial IgA deposits with steroid responsive nephrotic syndrome: probable minimal lesion nephrosis.
Two children presented with nephrotic syndrome. Renal biopsy demonstrated minimal lesion nephrosis with mesangial IgA deposits. Response to prednisone therapy was prompt in both cases. The clinical and histologic features of these and other reported cases suggested a diagnosis of minimal lesion nephrosis and not IgA nephropathy (Berger's disease).
D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005920:Glomerular Mesangium / Q000276:immunology* / Q000473:pathology; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D008297:Male; D009402:Nephrosis, Lipoid / Q000175:diagnosis; D009404:Nephrotic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D011241:Prednisone / Q000627:therapeutic use
D007070:Immunoglobulin A; D011241:Prednisone