[Antibacterial and antifungal agents. IV. Synthesis and antifungal activity of econazole analogs with pyrrole structure].
The synthesis of analogues of antifungal econazole with a pyrrole moiety starting from 1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethanone and from 1-(4-chlorophenyl)-2-(1H-pyrrol-1-yl)ethanol is described. Results of antimicrobial screening of the new derivatives in comparison with econazole are also reported.
D000935:Antifungal Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D004464:Econazole / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis*; D008352:Mannich Bases; D008826:Microbial Sensitivity Tests; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology
D000935:Antifungal Agents; D007093:Imidazoles; D008352:Mannich Bases; D011758:Pyrroles; D004464:Econazole
Ricerche su agenti antibatterici ed antifungini. Nota IV--Sintesi ed attività antifungina di analoghi dell'econazolo a struttura pirrolica.