[Homocarnosinase activity in the rat brain areas kidneys under different states of hyperbarooxygenation].
The homocarnosinase activity in different brain areas and kidneys of the normal rats and under different conditions of hyperbarooxygenation are determined. The highest activity of this enzyme is observed in cerebellum. The high homocarnosinase activity is typical of kidneys as well. The action of oxygen in a dose of 0.425 MPa for 60 min (in the absence of convulsions) increases the homocarnosinase activity in the cerebral hemispheres by 18.6%, in the midbrain by 18.6%, in midbrain and diencephalon--by 56.5%, and in the medulla oblongata--by 40.6%. The homocarnosinase activity in the cerebellum decreases by 16.7%, in kidneys--by 18.5%. At the convulsive stage of oxygen intoxication caused by the effect of 0.7 MPa dose of oxygen the homocarnosinase activity in cerebral hemispheres rises by 158.5%, in the midbrain and diencephalon--by 141.5%, in the medulla oblongata by--161.1%. Under the same conditions homocarnosinase activity in the cerebellum is unchanged as compared with the control.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D002531:Cerebellum / Q000201:enzymology; D004150:Dipeptidases / Q000378:metabolism*; D006931:Hyperbaric Oxygenation; D007668:Kidney / Q000201:enzymology*; D051381:Rats; D012640:Seizures / Q000201:enzymology
D004150:Dipeptidases; C019673:aminoacyl-histidine dipeptidase
Gomokarnozinaznaia aktivnost' v otdelakh golovnogo mozga i pochkakh krys pri raznykh rezhimakh giperbarooksigenatsii.