Effects of gonadectomy on the karyometric development of the ventromedial nucleus of the hypothalamus in the mouse.
We studied the karyometric development of 3 subdivisions (ventral, central and dorsal) of the ventromedial nucleus in male albino mice from the 5th to the 190th day of life. All subdivisions exhibited a similar development pattern. Another group of animals were castrated at the 20th day of life and examined from the 25th to the 85th day. The increase of the nuclear size at the 35th day and the decrease at the 85th day, observed in the control group, were not present after castration.
D000818:Animals; D002369:Castration; D002467:Cell Nucleus / Q000502:physiology; D005260:Female; D007620:Karyometry; D008297:Male; D051379:Mice; D013045:Species Specificity; D013739:Testosterone / Q000502:physiology*; D014697:Ventromedial Hypothalamic Nucleus / Q000254:growth & development*
D013739:Testosterone