[Morphofunctional status of the ovaries in patients with congenital adrenal cortical dysfunction].
The authors studied the morphofunctional state of the ovaries in 98 patients aged 15 to 40 with congenital adrenocortical dysfunction. It has been shown that primary amenorrhea and sterility observed in most of the patients were determined by changes in the ovaries and uterus as a result of a prolonged effect of androgens of adrenal origin. However these changes were reversible in nature because adequate glucocorticoid therapy is accompanied by the regeneration of ovarian function.
D000293:Adolescent; D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D000328:Adult; D000568:Amenorrhea / Q000503:physiopathology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007247:Infertility, Female / Q000503:physiopathology; D008597:Menstrual Cycle / Q000187:drug effects; D010053:Ovary / Q000187:drug effects / Q000503:physiopathology*; D011247:Pregnancy; D012098:Reproduction / Q000187:drug effects
D005938:Glucocorticoids
Morfofunktsional'noe sostoianie iaichnikov u bol'nykh s vrozhdennoĭ disfunktsieĭ kory nadpochechnikov.