[Incidence of chromosome aberrations in hothouse workers and the in vitro sensitivity of their lymphocytes to the cytogenetic action of dimatif].
The cytogenetical survey of eight persons working in greenhouse and occupationally contacting with a complex of pesticides has shown a significant increase of chromosomal aberration level in comparison with the control group. It is determined that the cytogenetic effect of the greenhouse's workers differed significantly from that of the control group when lymphocytes of the examined persons were treated by the potent mutagen dimatyph in vitro. The occupational group on the whole was more sensitive than control persons to the clastogenic action of dimatyph (43.0 +/- 2.2 and 28.7 +/- 2.4%, respectively). An assumption is advanced on the modifying influence of the pesticide complex on the frequency of induced chromosomal aberrations in vitro.
D000328:Adult; D000383:Agriculture; D001388:Aziridines / Q000494:pharmacology*; D001389:Azirines / Q000494:pharmacology*; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000648:ultrastructure; D008297:Male; D009153:Mutagens / Q000494:pharmacology*; D010573:Pesticide Residues / Q000009:adverse effects
D001388:Aziridines; D001389:Azirines; D009153:Mutagens; D010573:Pesticide Residues; C026085:dimatiph
Chastota aberratsiĭ khromosom u rabotnikov teplits i chuvstvitel'-nost' ikh limfotsitov in vitro k tsitogeneticheskomu deĭstviiu dimatifa.