[Effect of gamma-irradiation and neutrons on DNA-membrane complexes in mammalian cells].
The first results of the radiobiological studies obtained in a biophysical channel of the IBR-2 reactor at the Joint Institute for Nuclear Research are presented in this report. A study was made of the DNA-membrane complex sedimentation after exposure of Chinese hamster cells V79-4 to gamma-rays within a wide range of doses. The assumption, that had earlier been forwarded by the authors, of the role of double-strand DNA breaks in the alteration of a relative rate of the complex sedimentation upon irradiation of cells with doses above 50 Gy was confirmed.
D000818:Animals; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism / Q000528:radiation effects; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000378:metabolism / Q000528:radiation effects*; D004277:DNA, Single-Stranded / Q000378:metabolism / Q000528:radiation effects; D004278:DNA, Superhelical / Q000378:metabolism / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D009502:Neutrons; D012062:Relative Biological Effectiveness
D004277:DNA, Single-Stranded; D004278:DNA, Superhelical; D004247:DNA
Vozdeĭstvie gamma-izlucheniia i neĭtronov na DNK-membrannye kompleksy kletok mlekopitaiushchikh.