Raphe nucleus encephalopathy (myalgic encephalomyelitis, epidemic neuromyasthenia).
An injury to the dorsal raphe nucleus by Coxsackie B viruses is suggested as the cause of the disease sometimes called myalgic encephalomyelitis. The signs and symptoms are consistent with a serotonin deficiency in the dorsal raphe nucleus and the disease has a predisposition for women in nursing. Stress and underlying tryptophan deficiencies are considered as contributory factors.
D003384:Coxsackievirus Infections / Q000175:diagnosis* / Q000453:epidemiology; D004679:Encephalomyelitis / Q000175:diagnosis* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D009726:Nurses; D009784:Occupational Diseases / Q000453:epidemiology; D010146:Pain / Q000175:diagnosis; D011903:Raphe Nuclei; D012701:Serotonin / Q000172:deficiency*; D012737:Sex Factors; D013577:Syndrome
D012701:Serotonin