Antidepressants and myoclonus: case report.
Myoclonus is a movement disorder of various etiologies. An alteration in CNS serotonin activity is hypothesized to be the underlying mechanism for several myoclonic syndromes. Myoclonus has been reported as a side effect of antidepressants, and the serotonin hypothesis has been advanced to include this syndrome. A case is reported of myoclonus induced by an antidepressant purported to have no effect on serotonin activity.
D000928:Antidepressive Agents / Q000009:adverse effects*; D003866:Depressive Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D008376:Maprotiline / Q000009:adverse effects; D008875:Middle Aged; D009207:Myoclonus / Q000139:chemically induced* / Q000503:physiopathology; D012701:Serotonin / Q000502:physiology
D000928:Antidepressive Agents; D008376:Maprotiline; D012701:Serotonin