Tuberculous petrous apicitis.
Tuberculous osteomyelitis of the temporal bone is a rare and dangerous entity that should be included in the differential diagnoses of infectious processes of the base of skull. A 21-year-old man presented with petrous apicitis, extradural and retromandibular abscesses, and paresis of the facial nerve. Immediate middle fossa craniotomy and drainage of the extradural abscess, in combination with a mastoidectomy, incision and drainage of the facial abscess, and antimicrobial therapy for gram-positive cocci, failed to check the destructive nature of the infection. The patient subsequently developed labyrinthitis, sensorineural hearing loss, and meningitis. Intraoperative biopsy specimens confirmed the presence of tuberculoid granulomas, and the infectious process responded to triple-drug therapy. Tuberculosis of the temporal bone should not always be considered an indolent infection. The management of tuberculous infection of the temporal bone is outlined.
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D004427:Ear Diseases / Q000503:physiopathology / Q000601:surgery; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008297:Male; D008416:Mastoid / Q000601:surgery; D010019:Osteomyelitis; D010579:Petrous Bone / Q000000981:diagnostic imaging; D013701:Temporal Bone / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed; D014394:Tuberculosis, Osteoarticular / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery
D000995:Antitubercular Agents