Isolation of dealanylalahopcin, a new amino acid, and its biological activity.
A new amino acid, dealanylalahopcin, was isolated from a culture filtrate of Streptomyces albulus subsp. ochragerus; it was also formed by the enzymatic hydrolysis of alahopcin using microbial alpha-amino acid ester hydrolase. The amino acid was obtained as colorless needles and its molecular formula is C6H10N2O5. It showed very weak antibacterial activity against Gram-positive and Gram-negative bacteria, and weak inhibitory activity against the collagen prolylhydroxylase.
D000596:Amino Acids / Q000302:isolation & purification* / Q000494:pharmacology; D000613:Aminobutyrates / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D006868:Hydrolysis; D013302:Streptomyces / Q000378:metabolism*
D000596:Amino Acids; D000613:Aminobutyrates; D000900:Anti-Bacterial Agents; C045372:dealanylalahopcin