[Experimental evaluation of Bengal rose labeled with 123I].
Experimental evaluation of Bengal rose labeled with short-lived 123I was performed. The best diagnostic feature in 123I-Bengal rose were shown during a scintigraphic study of the rabbit liver and biliferous tract conducted in simultaneous experiments with the use of the agent labeled with 131I and 99mTc-HIDA. These were a high quality of the image of the organs, a low radiation exposure and the absence of extrahepatic uptake of the agent, particularly under conditions of the ligament of the common bile duct. The absence of a noticeable toxic effect of 123I-Bengal rose was established in experiments on rats and mice.
D000818:Animals; D005069:Evaluation Studies as Topic; D007457:Iodine Radioisotopes; D008099:Liver / Q000000981:diagnostic imaging*; D008297:Male; D051379:Mice; D011817:Rabbits; D011877:Radionuclide Imaging; D051381:Rats; D012395:Rose Bengal / Q000633:toxicity
D007457:Iodine Radioisotopes; D012395:Rose Bengal
Eksperimental'naia otsenka bengal'skogo rozovogo, mechennogo 123I]