Gustatory lacrimation in association with the branchio-oto-renal syndrome.
Branchio-oto-renal (BOR) syndrome is a developmental complex presenting with various combinations of ear pits, branchial cleft cysts, deafness and renal anomalies, which is inherited as an autosomal dominant trait. This report describes a father and 2 children with BOR syndrome in which gustatory lacrimation (GL) was also present in 2 of them. GL is considered to be a rare, non-hereditary type of anomalous, cranial nerve-end organ innervation. Since lacrimal stenosis, which can clinically mimic GL, is also a feature of the BOR syndrome, future reports require lacrimal reflex testing and duct patency evaluation to define this variation in the BOR phenotype.
D000328:Adult; D001935:Branchioma / Q000235:genetics*; D002675:Child, Preschool; D003638:Deafness / Q000235:genetics*; D004435:Eating; D005260:Female; D005799:Genes, Dominant; D006258:Head and Neck Neoplasms / Q000235:genetics*; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D008297:Male; D010641:Phenotype; D013577:Syndrome; D013649:Taste; D013666:Tears / Q000378:metabolism*