A comparison of opioid peptide precursors in guinea pig, rat and bovine striata and guinea pig adrenal.
In this study guinea pig, rat and bovine striatal extracts have been shown to contain putative opioid peptide precursors in the molecular weight (Mr) range 2000-greater than 70000. The material eluting greater than 70 kDalton contained bioassayable opioid activity but not Met- or Leu-enkephalin-like immunoreactivities (ME-IR and LE-IR) and may represent a novel endogenous opioid-peptide precursor.
D000311:Adrenal Glands / Q000032:analysis*; D000818:Animals; D043424:Carboxypeptidase B; D002268:Carboxypeptidases; D002384:Catalysis; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D003342:Corpus Striatum / Q000032:analysis*; D004723:Endorphins / Q000032:analysis*; D006168:Guinea Pigs; D008297:Male; D011498:Protein Precursors / Q000032:analysis*; D051381:Rats; D013045:Species Specificity; D014357:Trypsin
D004723:Endorphins; D011498:Protein Precursors; D002268:Carboxypeptidases; D043424:Carboxypeptidase B; D014357:Trypsin