Unilateral ureteric ligation in diabetic rats: a pathologic and morphometric study.
We studied the combined effect of unilateral ureteral ligation on the morphology and pathology of the contralateral kidney in normal and streptozotocin induced diabetic rats. In the diabetic group that underwent ligation of the right ureter the weight and volume of the left kidney was far greater, the tissue specific gravity far lower, while the percentage of affected glomeruli was significantly greater compared with control rats and those undergoing only ureteric ligation.
D000818:Animals; D003928:Diabetic Nephropathies / Q000209:etiology / Q000473:pathology*; D005260:Female; D007668:Kidney / Q000473:pathology; D008026:Ligation; D051381:Rats; D011919:Rats, Inbred Strains; D014513:Ureter