Combination chemotherapy of advanced renal cell cancer with CCNU and vinblastine.
No remission was achieved in 15 evaluable patients with measurable metastatic renal cancer treated with CCNU 120 mg/m2 (day 1) and vinblastine 0.1 mg/kg body weight (days 1 and 8) repeated every 6th week. Two additional patients were not evaluable for response owing to early death from progressive disease. Previously reported beneficial response rates in metastatic renal cancer after treatment with CCNU and vinblastine could not be confirmed.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy*; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy*; D008130:Lomustine / Q000008:administration & dosage; D014747:Vinblastine / Q000008:administration & dosage
D014747:Vinblastine; D008130:Lomustine