In vivo effects of glucocorticoids on serum corticosterone levels in rats.
In vivo effects of glucocorticoids on rat serum corticosterone level were investigated by using a simple and convenient HPLC-UV detection method. Serum corticosterone level was decreased by a single injection of hydrocortisone, methylprednisolone, betamethasone, dexamethasone or fluocinonide.
D000818:Animals; D001623:Betamethasone / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D003345:Corticosterone / Q000097:blood*; D003907:Dexamethasone / Q000494:pharmacology; D005447:Fluocinonide / Q000494:pharmacology; D005938:Glucocorticoids / Q000494:pharmacology*; D006854:Hydrocortisone / Q000494:pharmacology; D008297:Male; D008775:Methylprednisolone / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013056:Spectrophotometry, Ultraviolet
D005938:Glucocorticoids; D005447:Fluocinonide; D003907:Dexamethasone; D001623:Betamethasone; D003345:Corticosterone; D006854:Hydrocortisone; D008775:Methylprednisolone