Effects of ketamine on the catecholamine containing cells of the adrenal gland of the lizard Podarcis s. sicula Raf.
The authors studied the effects of ketamine on the morphology of the adrenal gland of Podarcis s. sicula Raf.. Low doses of the drug failed to anesthetize the lizards and did not cause significant changes in the morphology of the adrenal cells. Higher doses of ketamine caused deep anesthesia and marked depletion of catecholamine granules. The results support the theory that ketamine acts on the peripheral autonomic nervous system and sympathetic ganglia.
D000311:Adrenal Glands / Q000032:analysis / Q000187:drug effects* / Q000648:ultrastructure; D000818:Animals; D002395:Catecholamines / Q000032:analysis*; D007649:Ketamine / Q000494:pharmacology*; D008116:Lizards; D008297:Male
D002395:Catecholamines; D007649:Ketamine