[Estimation of partition coefficients using membrane electrodes].
The applicability of liquid membrane electrodes for estimation of partition coefficients is demonstrated. The correlation of selectivity coefficients of electrodes based on tricaprylmethylammonium-ion pairs with the octanol/water partition coefficients is demonstrated for several barbiturates. It is statistically significant and allows a simple estimation of partition coefficients.
D001463:Barbiturates / Q000032:analysis*; D002626:Chemistry, Pharmaceutical; D004566:Electrodes; D008567:Membranes, Artificial; D012995:Solubility
D001463:Barbiturates; D008567:Membranes, Artificial
Zur Ermittlung der Verteilungskoeffizienten mit Membranelektroden.