[NMR tomography of excised human lymph nodes].
The paper is concerned with the potentialities of the NMR-tomography technique (1H) for metastructure studying of the biopsied human lymph nodes both uninvolved and affected by tumor. Tomography was performed at 200 MHz using the Bruker CXP-200t mini-tomograph. Spin-echoes sequence and projection-reconstruction technique was employed. Spatial resolution was about 0.1 mm. Images of the uninvolved lymph nodes permitted one to detect the structure of the lymph nodes. NMR-imaging of unenlarged lymph nodes enabled one to localize the region of initial metastases. The reconstruction of various groups of spin-echo signals permitted a more precise detection of the regions differed in their spin-spin magnetic relaxation times T2 of protons in 1 mm slice. It may be assumed that the distinction in T2-relaxation rates of the normal and abnormal tissues displays an effective means to detect a pathological region using high-field tomography.
D000328:Adult; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008198:Lymph Nodes / Q000033:anatomy & histology; D008207:Lymphatic Metastasis / Q000175:diagnosis*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008545:Melanoma / Q000556:secondary; D008875:Middle Aged; D009333:Neck; D013964:Thyroid Neoplasms / Q000556:secondary
IaMR-tomografiia udalennykh limfaticheskikh uzlov cheloveka.