Hyperprolactinaemia and testosterone production. Observations in 2 men on long-term dialysis.
2 men had received maintenance dialysis for more than 5 years because of uraemia. Gradual impairment of libido had led to total impotence of more than 6 months duration. Concurrently hyperprolactinaemia occurred. Bromocriptine was given for 2 and 4 months, respectively. Potency was not restored, but in 1 patient the blood transfusion requirements were halved and general well-being and strength increased. In both men, the serum prolactin levels normalized. Inversely, the low plasma testosterone levels increased during the treatment period.
D000328:Adult; D001971:Bromocriptine / Q000494:pharmacology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D007989:Libido / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood*; D006435:Renal Dialysis; D013739:Testosterone / Q000097:blood*
D001971:Bromocriptine; D013739:Testosterone; D011388:Prolactin