[Effect of preliminary local myocardial hypoxia on the development of immune heart damage].
The changes in hemo- and cardiodynamics, myocardial contractility and its structural and histochemical alterations were studied in two series of experiments (immune and combined hypoxic and immune action on the myocardium) on 27 mongrel dogs anesthesized with chloralose and urethane. It was established that preliminary short-term hypoxia of the myocardium essentially increases the alterative effect of immune factors, causing a rise in the involved area as well as in the degree of metabolic shifts in this area and in the intensity of the disorders of heart function and hemodynamics.
D000818:Animals; D001327:Autoimmune Diseases / Q000209:etiology; D009202:Cardiomyopathies / Q000276:immunology*; D004285:Dogs; D000860:Hypoxia / Q000150:complications / Q000276:immunology*; D007106:Immune Sera / Q000633:toxicity*; D009206:Myocardium / Q000276:immunology*
D007106:Immune Sera
Vliianie predvaritel'noĭ lokal'noĭ gipoksii miokarda na razvitie immunogo povrezhdeniia serdtsa.