[Mathematical model of electromechanical coupling in the rat myocardium].
A mathematical modelling approach was used to study the negative staircase in the rat papillary muscle. This phenomenon was found to be associated with an excess of the steady-state Ca++-influx in the myocardium cells. The model with a single chamber intracellular Ca-pool simulates satisfactory the experimental data obtained with a standard set of parameter values. It is concluded that the rat myocardium sarcoplasmic reticulum is loaded by Ca++-ions which enter the cell as a potential-independent Ca-influx presumably.
D000200:Action Potentials; D000818:Animals; D004558:Electric Stimulation; D066298:In Vitro Techniques; D008433:Mathematics; D008955:Models, Cardiovascular; D009200:Myocardial Contraction; D010210:Papillary Muscles / Q000502:physiology; D051381:Rats
Matematicheskaia model' élektromekhanicheskogo sopriazheniia v miokarde krysy.