[Unusual muscular involvement in ankylosing spondylitis].
Muscle involvement in ankylosing spondylitis has been little studied. The authors report two cases with marked muscular atrophy and functional impotence, which had directed the diagnosis towards a myopathy over a period of several years in the first case, and a suspected primary muscular disease associated with ankylosing spondylitis in the second. Muscle biopsies eliminated the diagnosis of myopathy in both cases, with rapid functional recovery with proper treatment. Following a review of the literature, two hypotheses can be considered to explain the muscular involvement in ankylosing spondylitis: one mechanism which appears well-established is a radiculitis with involvement of the paravertebral muscles: other authors suggest that there is nonspecific, generalized muscular involvement in this disorder.
D000328:Adult; D001706:Biopsy; D003402:Creatine Kinase / Q000097:blood; D003937:Diagnosis, Differential; D004576:Electromyography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009133:Muscular Atrophy / Q000473:pathology; D009135:Muscular Diseases / Q000209:etiology* / Q000473:pathology; D013167:Spondylitis, Ankylosing / Q000150:complications*
D003402:Creatine Kinase
Atteinte musculaire inhabituelle au cours de la spondylarthrite ankylosante.