Hyperlipidaemia and premature coronary artery disease associated with sex-change in a female.
We describe the management of a genotypic female who developed hyperlipidaemia and premature coronary artery disease following bilateral oophorectomy and methyltestosterone administration, and present evidence to suggest that the therapeutic androgenization involved in the sex-change was responsible for the hyperlipidaemia.
D000328:Adult; D002369:Castration; D003327:Coronary Disease / Q000209:etiology*; D012734:Disorders of Sex Development; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000139:chemically induced*; D008777:Methyltestosterone / Q000009:adverse effects*
D008777:Methyltestosterone