Effects of cold stimulus of the chest wall on bronchial resistance.
We studied the possibility of inducing a bronchospasm by a cold stimulus (0 degrees C) on the chest wall of normal subjects and those with bronchial lability. The stimulus is applied on areas in metameric connection with the bronchial tree. Modifications of MEF25, MEF50 and FEV1.0 before and after stimulation are surveyed. Positive bronchospasm indexes are pointed out in a large number of subjects with bronchial lability, while no obstructive bronchial response is found in normal subjects. The cold stimulus on the chest wall can therefore be considered as an aspecific stimulus producing bronchospasm. Some physiopathogenetic interpretations are suggested.
D000293:Adolescent; D000328:Adult; D000403:Airway Resistance; D001980:Bronchi / Q000503:physiopathology*; D001982:Bronchial Diseases / Q000503:physiopathology; D001986:Bronchial Spasm / Q000209:etiology*; D002648:Child; D003080:Cold Temperature; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010812:Physical Stimulation; D012123:Pulmonary Ventilation; D013909:Thorax / Q000503:physiopathology*