The rationale for models studying mechanisms of teratogenesis.
Any model used in the integrated assessment of human teratogenesis needs to be consistent at morphogenetic, toxicodynamic, toxicokinetic, and population levels. These requirements can be met exclusively by theoretical models designed on the basis of particular problem-solving on laboratory animals. Only such models may contribute substantially to the direct prevention of human inborn defects.
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000818:Animals; D002642:Chick Embryo; D002972:Cleft Palate / Q000139:chemically induced; D000013:Congenital Abnormalities / Q000209:etiology*; D004195:Disease Models, Animal; D006801:Humans; D007700:Kinetics; D013723:Teratogens / Q000494:pharmacology
D013723:Teratogens