[Late potentials: non-invasive detection in coronary disease and relation to severe ventricular arrhythmia].
Using high-gain amplification and signal averaging techniques, we tried to determine the clinical significance of ventricular late potentials (LP). 85 subjects were included in this study. No LP were detected in normal subjects (n = 25), nor in patients with various non-coronary cardiopathies who had presented ventricular tachycardia and/or fibrillation (VT/VF) (n = 10). LP were recorded only in patients with coronary heart disease (CHD) (n = 50). The prevalence of LP was 50% (9/18) in patients with a history of VT/VF (vs 12.5% = 4/32 in patients without such a history, p less than 0.02). We also found a prevalence of 50% (11/22) in patients with a ventricular aneurysm (vs 7.1% = 2/28 in patients without an aneurysm, p less than 0.01). The prevalence reached 80% (8/10) in patients with VT/VF and a ventricular aneurysm and it was only in this latter group of patients that the interval between the peak of the R wave and the end of ventricular electrical activity exceeded 100 ms (mean 111.2 +/- 12 ms, vs 50 +/- 8 ms in normal subjects, p less than 0.001). In all the cases submitted to surgery, the LP disappeared after resection of the aneurysm. In conclusion, LP, when of long duration, should be considered as a hallmark of malignant ventricular arrhythmias in patients with CHD.
D000293:Adolescent; D000328:Adult; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000503:physiopathology*; D002648:Child; D003327:Coronary Disease / Q000150:complications / Q000503:physiopathology*; D004562:Electrocardiography; D006801:Humans; D008875:Middle Aged
Potentiels tardifs: détection non-invasive dans la maladie coronarienne et relation avec les arythmies ventriculaires graves.