[Flow fluorimetry of the cellular DNA of the bone marrow in normal mice and after exposure to extreme factors].
The distribution of murine bone marrow cells in regard to cell cycle was examined using flow cytometry technique. In normal NIH mice the percentage of cells being into phases G1/0, S and G2 + M constitutes 78, 15 and 7%, respectively. In mice subjected to X-irradiation (2, 12 Gy), the thermal burn, and X-irradiation plus the burn the proportion of G2 + M-cells increased, which may be presumably due to their delay on stage G2 of the cell cycle. The start and duration of the delay in the G2 phase depend upon the kind of damage applied.
D000818:Animals; D001853:Bone Marrow / Q000032:analysis* / Q000528:radiation effects; D001854:Bone Marrow Cells; D002056:Burns / Q000378:metabolism / Q000473:pathology; D002455:Cell Division / Q000528:radiation effects; D004247:DNA / Q000032:analysis* / Q000528:radiation effects; D005434:Flow Cytometry; D007399:Interphase / Q000528:radiation effects; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D013997:Time Factors
D004247:DNA
Protochnaia fluorimetriia DNK kletok kostnogo mozga mysheĭ v norme i posle vozdeĭstviia ékstremal'nykh faktorov.