Methylene dianilene: a new toxic cause of visual failure with hepatitis.
A 28-year-old man ingested methylene dianilene in potassium carbonate and gamma-butyrolactone. He developed toxic optic neuritis, with severe visual dysfunction (not previously reported in humans), prolonged toxic hepatitis, with disturbed liver-function tests 18 months after the incident, and other more transient effects. The course of his illness is described and the literature on methylene dianilene toxicity is reviewed.
D000328:Adult; D000814:Aniline Compounds / Q000506:poisoning*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004562:Electrocardiography; D005500:Follow-Up Studies; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D009902:Optic Neuritis / Q000139:chemically induced; D012160:Retina / Q000473:pathology; D014786:Vision Disorders / Q000139:chemically induced*; D001559:Benzhydryl Compounds
D000814:Aniline Compounds; C009505:4,4'-diaminodiphenylmethane; D001559:Benzhydryl Compounds