Field efficacy of a morantel sustained release bolus for control of gastrointestinal nematodes in yearling steers.
The efficacy of a morantel sustained release bolus (MSRB) for control of gastrointestinal nematodes in yearling steers was evaluated over a 6-month grazing period commencing on 26 March 1982. Three groups of 15 steers were allotted to the following treatments: Group 1 -- one MSRB at start of trial; Group 2 -- one therapeutic dose of thiabendazole at start of trial; Group 3 -- untreated control. The treatment groups were grazed separately. Parasite egg counts (EPG), herbage larval counts, pepsinogen levels and weight gains were monitored. Every other month, sets of 2 parasite-free tracer calves were placed in the pasture grazed by each treatment group and allowed to graze for 3 weeks before being subsequently necropsied for worm counts. At the end of the trial, 6 animals from each group were also necropsied for worm counts. The MSRB treatment resulted in significantly lower egg counts, fewer infective larvae on pasture, lower pepsinogen levels and lower worm burdens in tracer calves than was the case for the untreated group, but generally the levels were not significantly different from those associated with the thiabendazole treatment. The mean weight gain for the MSRB treated steers showed a significant advantage (70.9 lb) over the untreated animals, but was not significantly different from those which received thiabendazole. Total worm counts at the end of the trial were not different from any treatment group.
D000018:Abomasum / Q000469:parasitology; D000818:Animals; D001835:Body Weight; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000517:prevention & control*; D003692:Delayed-Action Preparations; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D007420:Intestine, Large / Q000469:parasitology; D007421:Intestine, Small / Q000469:parasitology; D007814:Larva; D008297:Male; D009015:Morantel / Q000008:administration & dosage* / Q000627:therapeutic use; D009348:Nematoda / Q000254:growth & development; D009349:Nematode Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D010270:Parasite Egg Count; D010435:Pepsinogens / Q000097:blood; D011743:Pyrimidines / Q000008:administration & dosage*; D013827:Thiabendazole / Q000627:therapeutic use
D003692:Delayed-Action Preparations; D010435:Pepsinogens; D011743:Pyrimidines; D009015:Morantel; D013827:Thiabendazole