Study of the hypnic effect of amineptine evaluation by means of polygraphy and tests.
The sleep pattern and conditions at the time of awakening were investigated by means of polygraphy and tests in 6 healthy adult volunteers following administration of amineptine. The drug was found to increase the number and duration of the REM phases, without affecting the overall sleeping time but reducing sleep latency. The tests carried out revealed a higher sensation of well-being, improved attention and concentration in the morning.
D000328:Adult; D003986:Dibenzocycloheptenes / Q000494:pharmacology*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D011930:Reaction Time / Q000187:drug effects; D012890:Sleep / Q000187:drug effects*; D012894:Sleep Stages / Q000187:drug effects
D003986:Dibenzocycloheptenes; D006993:Hypnotics and Sedatives; C011597:amineptin