Flucloxacillin-induced cholestatic liver damage.
Two female patients (75 and 68 yr old) developed jaundice 4 and 7 weeks respectively after treatment with flucloxacillin. Liver biopsies showed intrahepatic cholestasis. After cessation of the drug, the liver tests became normal.
D000368:Aged; D002780:Cholestasis, Intrahepatic / Q000139:chemically induced* / Q000473:pathology; D003023:Cloxacillin / Q000031:analogs & derivatives*; D005260:Female; D005436:Floxacillin / Q000009:adverse effects*; D006801:Humans; D008099:Liver / Q000473:pathology
D005436:Floxacillin; D003023:Cloxacillin