Recombination-deficient Streptococcus sanguis.
A UV-sensitive derivative was obtained from Streptococcus sanguis Challis. The organism could be transformed with a number of small streptococcal plasmids at frequencies equal to, or 1 logarithm below, the transformation frequencies for the parent organism. However, transformation with chromosomal DNA was greatly impaired in the UV-sensitive derivative.
D008741:Methyl Methanesulfonate / Q000494:pharmacology; D009154:Mutation; D010957:Plasmids; D011995:Recombination, Genetic; D013298:Streptococcus sanguis / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D014169:Transformation, Bacterial; D014466:Ultraviolet Rays
D008741:Methyl Methanesulfonate