DNAse I-actin complex: an immunological study.
DNAse I-actin complex formation is studied in the presence of different anti actin antibody populations. The binding of DNAse I to actin is shown to be affected by antibodies specific to a central region in actin sequence (168-226). The C- and N-extremities of actin are shown to be in spatial proximity at the surface of the actin monomer and far from the binding area of DNAse I.
D000199:Actins / Q000276:immunology*; D000595:Amino Acid Sequence; D000818:Animals; D000906:Antibodies / Q000276:immunology; D001665:Binding Sites; D003850:Deoxyribonuclease I / Q000276:immunology*; D007120:Immunochemistry; D011817:Rabbits
D000199:Actins; D000906:Antibodies; D003850:Deoxyribonuclease I