Reference ranges for IgG subclasses in preschool children.
A normal range for IgG1, IgG2, and IgG3 subclasses has been established for children aged 6 months to 5 years using commercially available monoclonal antisera. Of particular interest were the very low concentrations of IgG2 in some healthy children, a finding which casts doubt on the importance of IgG2 deficiency reported in some patients with otherwise unexplained infections. It was not possible to construct a normal range for IgG4 values probably because these segregate into two populations in normal subjects.
D000375:Aging; D000911:Antibodies, Monoclonal / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis* / Q000145:classification; D007223:Infant; D012016:Reference Values
D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G