Macular hole and retinal detachment in Best's disease.
The authors report a family with Best's vitelliform macular dystrophy in which one member developed a macular hole and retinal detachment. The retinal detachment was repaired by resultant extensive rhegmatogenous pars plana vitrectomy, fluid-air exchange, and photocoagulation. Examination of the vitreous specimen disclosed numerous large macrophages with abundant cytoplasm distended by lipofuscin.
D000293:Adolescent; D000328:Adult; D002648:Child; D006801:Humans; D008028:Light Coagulation; D008266:Macula Lutea / Q000473:pathology; D008268:Macular Degeneration / Q000150:complications* / Q000235:genetics / Q000473:pathology; D008297:Male; D012163:Retinal Detachment / Q000209:etiology* / Q000601:surgery / Q000628:therapy; D012167:Retinal Perforations / Q000209:etiology*; D014821:Vitrectomy