Lymphangiography and computerized tomography in testicular carcinoma: how accurate in early stage disease?
The usefulness of lymphangiography and computerized tomography was evaluated in 167 consecutive patients with pathological stages I and II testicular carcinoma and metastases of less than 5 cm. Lymphangiography demonstrated 74.4 per cent sensitivity, 77.6 per cent specificity and 76.0 per cent over-all accuracy. Computerized tomography revealed comparable results, with 74.3 per cent over-all accuracy, 73.7 per cent sensitivity and 75.0 per cent specificity. The combination of lymphangiography and computerized tomography performed in 35 patients consistently improved the diagnostic possibilities of either technique alone in patients with positive nodes, reducing the false negative rate from 27 to 10 per cent. On the other hand, this combination increased the false positive rate from 25 to 37 per cent in patients with negative nodes. In patients with clinical stage I disease for whom a wait-and-see policy after orchiectomy is adopted at our institute both methods must be considered mandatory. In all other situations computerized tomography alone should be the preferred procedure in the diagnosis of retroperitoneal lymph node metastases from testicular carcinoma.
D002277:Carcinoma / Q000000981:diagnostic imaging*; D005188:False Negative Reactions; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging; D008220:Lymphography; D008297:Male; D012187:Retroperitoneal Space; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging*; D013737:Testis / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed