Theophylline-associated seizures in children.
Four patients are reported who experienced seizures in association with serum theophylline concentrations which were in the mildly toxic range. In three patients, erythromycin administration was a probable factor contributing to the elevated theophylline levels. One patient suffered severe neurologic damage as a result of the seizure.
D002648:Child; D004917:Erythromycin / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D012640:Seizures / Q000209:etiology*; D013806:Theophylline / Q000097:blood* / Q000633:toxicity
D004917:Erythromycin; D013806:Theophylline