[Clinical and experimental amyotrophic leukospongiosis (progressive spinal amyotrophy)].
The authors succeeded in reproducing amyotrophic leukospongiosis in experiments on two squirrel monkeys 16-23 months after challenge with cerebral suspension obtained at autopsy from a human patient. The clinico-morphological studies showed the similarity of the disease in humans and monkeys. A previously unknown agent belonging by its properties to "slow" viruses was isolated. The successful reproduction of amyotrophic leukospongiosis under experimental conditions proved its infectious nature.
D000818:Animals; D001921:Brain / Q000382:microbiology; D002490:Central Nervous System / Q000473:pathology; D004195:Disease Models, Animal; D006801:Humans; D009133:Muscular Atrophy / Q000473:pathology; D012453:Saimiri; D012897:Slow Virus Diseases / Q000473:pathology; D013118:Spinal Cord Diseases / Q000473:pathology
Amiotroficheskiĭ leĭkospongioz (progressiruiushchaia spinal'naia amiotrofiia) v klinike i éksperimente.