Drinking by senescent and adult rats in response to regulatory challenges.
The regulation of water and electrolyte balance was elevated in senescent (greater than 31 months) and adult (5-10 months) rats of several strains. Weekly food and water intake, drinking induced by 24-hr water deprivation and drinking induced by injection of hypertonic saline were roughly the same in old and adult rats. However, senescent rats drank less after injection of the beta-adrenergic agonist isoprenaline than adult rats. There were no appreciable strain differences in drinking in response to these regulatory challenges although baselines sometimes differed between strains.
D000375:Aging; D000818:Animals; D004326:Drinking / Q000187:drug effects; D004435:Eating; D005260:Female; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012462:Saline Solution, Hypertonic; D014868:Water Deprivation; D014882:Water-Electrolyte Balance
D012462:Saline Solution, Hypertonic; D007545:Isoproterenol