Nitrogen balance: an adequate treatment prescription index for children on haemofiltration.
We studied 12 children (10.6 +/- 2.5 years; 21 +/- 4.8 kg body weight) with end-stage renal disease on chronic haemofiltration prescribed using a urea kinetic model. After 12 months, urea generation rate, protein catabolic rate and nitrogen balance were assessed in each patient. Pre-treatment BUN was adequate in all 12 patients but in three nitrogen balance and growth rate were unsatisfactory. These three children were studied for a second year in which plasma water cleared/week was increased; during this year a significant increase in nitrogen balance and growth rate was obtained.
D001769:Blood; D002648:Child; D006801:Humans; D007676:Kidney Failure, Chronic / Q000378:metabolism / Q000628:therapy; D009584:Nitrogen / Q000378:metabolism*; D014462:Ultrafiltration
D009584:Nitrogen