Tumor antigens and immune complexes in laryngeal cancer.
The sensitivity of an antigen prepared from tumor extract in three concentrations was examined in patients with cancers of the larynx of different extent (T1-T4) with or without metastases. At the same time circulating immune complexes in the serum were investigated by the polyethylene glycol precipitation method. Positive antigen reactions were found in 34% of the cases examined and enhanced immune complexes alone in 66%. These results were compared before and after the operative procedures and their relationship to the phytohaemagglutinin was assessed. Differences in these results appeared to be related to the size of the tumors (T1-T4) and to the presence of metastases.
D000936:Antigen-Antibody Complex / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000276:immunology*; D011232:Chemical Precipitation; D006801:Humans; D007822:Laryngeal Neoplasms / Q000276:immunology* / Q000473:pathology; D008213:Lymphocyte Activation; D010835:Phytohemagglutinins / Q000494:pharmacology; D011092:Polyethylene Glycols
D000936:Antigen-Antibody Complex; D000951:Antigens, Neoplasm; D010835:Phytohemagglutinins; D011092:Polyethylene Glycols