Outpatient management of cervical intraepithelial neoplasia. A summary of 279 cases.
Two hundred seventy-nine patients with cervical condylomas or cervical intraepithelial neoplasia (CIN) were treated as outpatients with cryotherapy. Every patient followed received a Papanicolaou smear, colposcopic evaluation, cervical biopsy and endocervical curettage four months following treatment. The treatment failure rates for CIN 1/condyloma, CIN 2 and CIN 3 were 2.9%, 5.7% and 4.3%, respectively. The percentage of patients eventually requiring conization was 0.7, 1.6 and 2.7, respectively. No patient who had a negative clinical and histologic examination at four months subsequently had a recurrence. The mean follow-up was 23.1, 26.0 and 35.0 months for CIN 1/condyloma, CIN 2 and CIN 3, respectively. Proper triage is important with CIN 3, and a complete colposcopic examination at the initial follow-up visit is valuable for predicting outcome.
D000556:Ambulatory Surgical Procedures; D001706:Biopsy; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000601:surgery*; D003127:Colposcopy; D003218:Condylomata Acuminata / Q000175:diagnosis / Q000601:surgery*; D003452:Cryosurgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D065006:Papanicolaou Test; D011182:Postoperative Care; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000601:surgery*; D014626:Vaginal Smears