Treatment of vaginal candidosis with tioconazole 2% vaginal cream.
Six hundred and three women in a contraceptive clinic were examined for the presence of C. albicans in the vagina and questioned about symptoms. Twenty-nine women with C. albicans accompanied by symptoms were treated with tioconazole 2% in a vaginal cream for 3 days, repeated once after an interval of 1 week. The mycological cure rate was 88.5%. At the same time, 34 women with vaginal C. albicans but without symptoms were examined. The spontaneous cure rate in these patients was 58.8%. In the symptomatic group, rectal C. albicans was observed in 56.5% of patients before treatment. After vaginal treatment, a rectal cure rate of 100% was achieved, but with a recurrency frequency after 2-4 weeks of 17.4%. Comparative vaginal recurrency frequency was 10.3%. Three were not cured. The method used has shown itself to be very acceptable for the patient and to have a cure frequency that is fully equal to previously used, longer lasting treatments.
D000293:Adolescent; D000328:Adult; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D012008:Recurrence; D014622:Vaginal Creams, Foams, and Jellies
D007093:Imidazoles; D014622:Vaginal Creams, Foams, and Jellies; C020527:tioconazole