Naloxone-reversible respiratory inhibition induced by muscular thin-fiber afferents in decerebrated cats.
Stimulation of muscular thin-fiber afferents of cats causes two types of respiratory suppression: one is stimulus-locked suppression which is not affected by naloxone, and the other is naloxone-reversible respiratory suppression after cessation of the stimulation. Both types of respiratory suppression could still be evoked after decerebration of cats at the midcollicular level. The present experiment revealed that muscular thin-fiber afferents, presumably polymodal receptor afferents, caused respiratory inhibition mediated through an opiate system in the brain structure below the caudal part of the brain stem.
D000818:Animals; D001933:Brain Stem / Q000502:physiology*; D002415:Cats; D003655:Decerebrate State / Q000503:physiopathology; D004723:Endorphins / Q000502:physiology*; D009132:Muscles / Q000294:innervation*; D009270:Naloxone / Q000494:pharmacology; D009475:Neurons, Afferent / Q000502:physiology; D009482:Neurophysiology / Q000379:methods; D012119:Respiration
D004723:Endorphins; D009270:Naloxone