Mouth and genital ulcers with inflamed cartilage: MAGIC syndrome. Five patients with features of relapsing polychondritis and Behçet's disease.
Five patients with features of coexistent relapsing polychondritis and Behçet's disease are described. Review of the literature supports the overlap of the clinical manifestations of these two conditions. A common immunologic abnormality is likely, and elastin is cited as a possible target antigen. The "mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome" is the proposed name for this entity.
D000328:Adult; D001323:Autoantibodies / Q000276:immunology; D001528:Behcet Syndrome / Q000150:complications* / Q000276:immunology; D002648:Child; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications; D005832:Genital Diseases, Male / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000150:complications; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000276:immunology; D012883:Skin Ulcer / Q000150:complications; D014456:Ulcer / Q000150:complications
D001323:Autoantibodies