Effect of antiepileptic drugs on short-latency somatosensory evoked potentials.
Short-latency somato sensory evoked potentials (SEPs) were recorded in 45 freshly diagnosed cases of epilepsy before starting treatment. Follow-up recordings were made 6 weeks and 3 months after diphenylhydantoin, carbamazipine and phenobarbitone monotherapy were started. Serum drug levels were monitored. Both amplitude and latency of the initial component (N20) remained unchanged and were identical to a group of 30 age- and sex-matched normal individuals in whom SEPs were recorded during the period of study.
D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D002220:Carbamazepine / Q000627:therapeutic use; D002648:Child; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004827:Epilepsy / Q000188:drug therapy*; D005073:Evoked Potentials, Somatosensory / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010634:Phenobarbital / Q000627:therapeutic use; D010672:Phenytoin / Q000627:therapeutic use; D011930:Reaction Time / Q000187:drug effects
D000927:Anticonvulsants; D002220:Carbamazepine; D010672:Phenytoin; D010634:Phenobarbital