The effect of aromatic retinoid Ro 10-9359 (etretinate) on fingernail growth.
Fingernail growth was studied in 28 patients who were receiving systemic treatment with the aromatic retinoid, Ro 10-9359 known as Tigason (etretinate; AR). A group of 15 patients with psoriasis was compared with a group of 13 patients with other dermatoses which are known to have a good response to AR therapy. In the second group, oral therapy with AR appeared to have no effect on the daily growth rate of fingernails (99 +/- 4 microns). With AR treatment, the nail-plate growth rate in the psoriatics increased to 132 +/- 5 microns.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005050:Etretinate / Q000627:therapeutic use*; D005260:Female; D005385:Fingers; D006801:Humans; D008297:Male; D008875:Middle Aged; D009262:Nails / Q000187:drug effects / Q000254:growth & development* / Q000473:pathology; D011565:Psoriasis / Q000188:drug therapy*; D012871:Skin Diseases / Q000188:drug therapy*
D005050:Etretinate