[Deep mycoses in leukemias and malignant lymphomas].
Of 590 autopsies during the period 1976 to 1983 in patients with leukaemia and malignant lymphomas there were 89 cases (15%) involving deep-seated mycoses. In the last three years the frequency of mycotic infections has risen considerably even though effective drugs are available today. The increase occurred particularly in acute leukaemias but was also found in chronic myelogenous leukaemias and in cases with high-malignancy non-Hodgkin lymphomas. An opportunistic fungal infection in Hodgkin's disease and in patients with plasmocytoma was rare. Candidosis and aspergillosis predominated histologically. About 70% of deep-seated mycoses were severe infections having a decisive influence on the course of the disease. On the basis of this retrospective analysis it can be concluded that the occurrence of mycoses is influenced, first and foremost, by 3 factors: 1. The antineoplastic therapy 2. The nature of the underlying disease 3. The intensity of the supportive measures.
D001228:Aspergillosis / Q000453:epidemiology; D001344:Autopsy; D002177:Candidiasis / Q000453:epidemiology; D005860:Germany, West; D006801:Humans; D007938:Leukemia / Q000150:complications*; D008223:Lymphoma / Q000150:complications*; D009181:Mycoses / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies
Tiefe Mykosen bei Leukämien und malignen Lymphomen.