Prevalence of posterior subcapsular lens opacities in patients with retinitis pigmentosa.
We clinically evaluated 338 patients with various genetic types of retinitis pigmentosa (RP) for the presence of posterior subscapsular (PSC) lens opacities. Of these, 180 (53%) had PSC lens changes or were bilaterally aphakic. Patients with X-linked recessive RP showed a greater prevalence and patients with autosomal dominant RP a lesser prevalence of PSC lens changes compared with autosomal recessive or isolated cases.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002386:Cataract / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005799:Genes, Dominant; D005808:Genes, Recessive; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D008875:Middle Aged; D012174:Retinitis Pigmentosa / Q000150:complications* / Q000235:genetics; D014960:X Chromosome