Theophylline-lithium interaction.
The effect of steady state therapeutic theophylline serum levels on lithium renal clearance was investigated. Group mean lithium renal clearances and serum lithium levels varied in predicted fashion. Individual variability in these parameters was significant. Clinical implications are considered and management suggestions made.
D000328:Adult; D004347:Drug Interactions; D005260:Female; D006801:Humans; D007700:Kinetics; D008094:Lithium / Q000097:blood / Q000378:metabolism / Q000494:pharmacology*; D008297:Male; D013806:Theophylline / Q000097:blood / Q000378:metabolism / Q000494:pharmacology*
D008094:Lithium; D013806:Theophylline