Conformational requirements of tobacco mosaic virus RNA for aminoacylation and adenylation.
The RNA conformational requirements for both aminoacylation and adenylation emerging from our studies performed using the valine- and the tyrosine-accepting plant viral RNAs are now strongly supported by the histidine-accepting tobacco mosaic virus RNA: an 'L'-shaped conformation is recognized by the aminoacyl-tRNA synthetase whereas only the aminoacyl RNA domain (equivalent in tRNAs to the continuous helix formed by the acceptor stem and the T stem and loop) interacts with the tRNA nucleotidyltransferase.
D000604:Amino Acyl-tRNA Synthetases / Q000378:metabolism*; D008970:Molecular Weight; D009690:Nucleic Acid Conformation; D012316:RNA Nucleotidyltransferases / Q000378:metabolism*; D012367:RNA, Viral / Q000378:metabolism; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D014027:Tobacco Mosaic Virus / Q000378:metabolism*
D012367:RNA, Viral; D012316:RNA Nucleotidyltransferases; C023198:tRNA nucleotidyltransferase; D000604:Amino Acyl-tRNA Synthetases