Fragile X syndrome: a public health concern.
This study was designed to test for the fragile X syndrome [fra(X)] in institutionalized male patients with nonspecific mental retardation, referral patients, and relatives of fra(X) patients. Thirty-one of 91 (34.0 per cent) subjects tested were positive for the fra(X) chromosome; relatives had the largest percentage of positives. The data reflect the value of this test for detecting families having potential carriers who can benefit from genetic counseling.
D005260:Female; D005600:Fragile X Syndrome / Q000175:diagnosis*; D005845:Georgia; D006801:Humans; D007326:Institutionalization; D008607:Intellectual Disability / Q000235:genetics; D008297:Male; D012306:Risk; D012729:Sex Chromosome Aberrations / Q000175:diagnosis*