Acid ingestion in an experimental model.
Following acid ingestion, the mortality of operative intervention is clearly related to late recognition of perforation. Experimentally, fiber-optic endoscopy can be used to accurately predict the depth of gastric injury. Operative intervention can be undertaken before gross perforation. Flexible endoscopy should be performed upon admission and repeated at intervals of 12 to 24 hours until one is satisfied that the injury is stable, reversible and will not progress. The risk of gastric perforation is minimal if the endoscopic procedure is performed by a competent individual. Continued careful medical follow-up examination and nutritional support is indicated when major damage to the stomach occurs to ensure that the patient will tolerate anticipated operative reconstruction.
D000143:Acids / Q000506:poisoning*; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002424:Caustics / Q000506:poisoning; D002675:Child, Preschool; D004195:Disease Models, Animal; D004285:Dogs; D004947:Esophagus / Q000187:drug effects / Q000473:pathology; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology; D005773:Gastroscopy; D006801:Humans; D006851:Hydrochloric Acid / Q000506:poisoning; D009336:Necrosis; D013270:Stomach / Q000601:surgery; D013464:Sulfuric Acids / Q000506:poisoning
D000143:Acids; D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D002424:Caustics; D013464:Sulfuric Acids; C033158:sulfuric acid; D006851:Hydrochloric Acid