Two-dimensional proton nuclear magnetic resonance "maps" of acetaminophen metabolites in human urine.
Two-dimensional proton-proton correlated NMR spectra of concentrated urine from a subject who had ingested a 1-g dose of acetaminophen are reported. These "maps" provide a considerable simplification of the spectrum in comparison with conventional one-dimensional NMR spectra. In the present case, peaks for all the major acetaminophen metabolites, including the L-cysteinyl conjugate, can be unambiguously assigned.
D000082:Acetaminophen / Q000652:urine*; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D013329:Structure-Activity Relationship
D000082:Acetaminophen