Translocation (11;22) in Ewing's sarcoma.
A cytogenetic study carried out by a direct method on the tumor of a patient with Ewing's sarcoma showed a t(11;22) in the six cells studied. The fact that this structural alteration was detected by a direct method indicates that the translocation is present in Ewing's sarcoma cells and that this alteration, when detected in established cell lines and short-term cultures, is not an alteration induced by the conditions of culture.
D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics*; D002648:Child; D002904:Chromosomes, Human, 21-22 and Y; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D007621:Karyotyping; D008297:Male; D011859:Radiography; D012272:Ribs; D012512:Sarcoma, Ewing / Q000000981:diagnostic imaging / Q000235:genetics*; D014178:Translocation, Genetic