Plasma warfarin concentrations after a massive overdose.
The plasma pharmacokinetics of warfarin were studied in a patient who took an overdose of warfarin (2000 mg by mouth), together with 25 X 10(4) units of heparin administered subcutaneously. The plasma warfarin level fell rapidly (half-life, 21.7 h), and there was no convincing evidence for dose-dependency in its disposition.
D006493:Heparin / Q000506:poisoning; D006801:Humans; D007279:Injections, Subcutaneous; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D014859:Warfarin / Q000097:blood / Q000506:poisoning*
D014859:Warfarin; D006493:Heparin