Lyme disease in a 12-year-old girl.
We report the case of a 12-year-old girl with erythema chronicum migrans, aseptic meningitis and knee arthralgia. Rise of specific antibody titre against an Ixodes ricinus spirochaete was demonstrated. Circulating immune complexes and high levels of C1r-C1s-C1IA complexes indicating activation of the complement system via the classical pathway were found. The clinical features and the laboratory findings warranted a diagnosis of Lyme disease.
D000936:Antigen-Antibody Complex / Q000032:analysis; D002648:Child; D003165:Complement System Proteins / Q000032:analysis; D004890:Erythema / Q000276:immunology; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis / Q000276:immunology*; D008582:Meningitis, Aseptic / Q000175:diagnosis / Q000276:immunology
D000936:Antigen-Antibody Complex; D003165:Complement System Proteins