[Individual and age-related characteristics of the mitotic condensation of human Y chromosome].
Three types of contraction (steady, speeding and slowing) of fluorescent (f) and nonfluorescent (nf) parts of the human Y chromosome were revealed in the spiralization interval limited by reper chromosome 3 length from 16.6 to 2.9 mkm. On the basis of regression analysis it was shown that in the initial phase of the spiralization interval studied the f-block was condensed more rapidly than the nf-region; then the speed of contraction of the latter exceeded that of the former. A decline of the Y chromosome condensation in relation to ageing was revealed. A possible chromosome segregation disturbance in gametogenesis due to senescent changes of heterochromatic regions is discussed.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D002648:Child; D002675:Child, Preschool; D005453:Fluorescence; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D008938:Mitosis; D012044:Regression Analysis; D014998:Y Chromosome / Q000648:ultrastructure*
Individual'nye i vozrastnye osobennosti mitoticheskoĭ kondensatsii Y-khromosomy cheloveka.