Unusual pigmentation on the skin over trunk bones and extremities.
6 young people (19-31 years old) exhibited unusual light or dark brown, ill-circumscribed or reticular pigmentation distributed over protrudent bones. 5 of them have been using nylon towels and scrub brushes for over 3-10 years. Biopsy specimens showed that the amount of melanin granules in the basal layer was increased and melanophages were scattered in the upper dermis. Inflammatory infiltrates were minimal.
D000328:Adult; D001415:Back; D005121:Extremities; D005260:Female; D006801:Humans; D007509:Irritants; D008297:Male; D009757:Nylons; D010859:Pigmentation Disorders / Q000209:etiology*
D007509:Irritants; D009757:Nylons