Sequential changes of sensory neuron (fluoride-resistant) acid phosphatase in dorsal root ganglion neurons following neurectomy and rhizotomy.
Five to seven days after sciatic nerve section in rats, fluoride-resistant acid phosphatase (FRAP) expression in dorsal root ganglion (drg) neurons was markedly decreased. The decrease was in contrast to increased acid phosphatase which has been reported to occur in other neurons after nerve section. FRAP expression in ganglion neurons subsequently increased 14-21 days after nerve section; this preceded the restitution of enzyme expression in the spinal cord substantia gelatinosa. FRAP expression in drg neurons was not decreased after dorsal root section.
D000135:Acid Phosphatase / Q000378:metabolism*; D000818:Animals; D004351:Drug Resistance; D005260:Female; D005459:Fluorides / Q000494:pharmacology; D005727:Ganglia, Spinal / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013126:Spinal Nerve Roots / Q000293:injuries; D013127:Spinal Nerves / Q000293:injuries*
D000135:Acid Phosphatase; D005459:Fluorides