Central pontine myelinolysis in a child with the Shwachman-Diamond syndrome.
The first case of central pontine myelinolysis in a child with the Shwachman-Diamond syndrome is reported. Marked fluctuation of serum glucose and sodium levels, but no hyponatremia, was observed throughout the patient's hospital course. Both of these abnormalities may have contributed to the development of the lesion. Liver abnormalities, implicated in other pediatric cases of central pontine myelinolysis, were also observed.
D000740:Anemia / Q000150:complications; D001927:Brain Diseases / Q000473:pathology*; D002648:Child; D002712:Chlorides / Q000032:analysis; D003711:Demyelinating Diseases / Q000473:pathology*; D010188:Exocrine Pancreatic Insufficiency / Q000150:complications*; D005260:Female; D006130:Growth Disorders / Q000150:complications; D006801:Humans; D009503:Neutropenia / Q000150:complications; D011149:Pons / Q000473:pathology; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications
D002712:Chlorides