Ranitidine hydrochloride-induced hypergastrinemia.
Ranitidine hydrochloride (Zantac) is a recently released H(2)-receptor antagonist that is stated not to cause significant increases in serum gastrin. The case described herein demonstrates that this is not always true. Zantac produced significant acute hypergastrinemia, which was sustained for several days after the discontinuation of the drug.
D005260:Female; D005755:Gastrins / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D011899:Ranitidine / Q000009:adverse effects*; D013997:Time Factors
D005755:Gastrins; D011899:Ranitidine