[Skin manifestations in sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman syndrome)].
We report on a 19-year-old girl suffering from cutaneous manifestation of sinus histiocytosis associated with massive lymphadenopathy (SHML) (Rosai-Dorfman syndrome); as SHML had first appeared at her 7th month of life, the disease had taken an uncommonly long period of time. At the age of 15, cutaneous manifestations developed on cheeks and left upper arm which histologically showed the same infiltrate as affected lymph nodes usually do in SHML. So far, participation of the cutaneous system in SHML has been observed in only 12 cases.
D000328:Adult; D005260:Female; D005487:Foam Cells / Q000166:cytology; D006644:Histiocytes / Q000166:cytology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000473:pathology*; D008214:Lymphocytes / Q000166:cytology; D010950:Plasma Cells / Q000166:cytology; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000473:pathology*; D013577:Syndrome
Hautveränderungen bei Sinushistiozytose mit massiver Lymphadenopathie (SHML) (Rosai-Dorfman-Syndrom).