Bronchopulmonary candidiasis exacerbating asthma. Case report and review of the literature.
We describe a perplexing asthmatic patient who had chronic lymphatic leukemia that developed recurrent severe and prolonged attacks of asthma which required almost continuous hospitalization. Clinical findings of fever, leukocytosis, right lower lobe infiltrate and mouth candidiasis were suggestive of bronchopulmonary candidiasis. No further diagnostic tests were done and the patient responded favorably to amphotericin B therapy. A review of bronchopulmonary candidiasis in adults is discussed briefly. Lung biopsy should be reserved only for the most obscure and problematic cases.
D000666:Amphotericin B / Q000627:therapeutic use; D001249:Asthma / Q000150:complications*; D002177:Candidiasis / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000150:complications*; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000188:drug therapy; D008875:Middle Aged
D000666:Amphotericin B