Successful treatment of neuroleptic-induced akathisia with baclofen and clonazepam. A case report.
A patient with neuroleptic-induced akathisia was successfully treated with a combination of baclofen (a GABA agonist) and clonazepam (a serotonergic agent). This suggests that agents bypassing the dopaminergic systems may be effective in the treatment of this distressing disorder.
D017109:Akathisia, Drug-Induced; D001418:Baclofen / Q000627:therapeutic use*; D001570:Benzodiazepinones / Q000627:therapeutic use*; D002998:Clonazepam / Q000627:therapeutic use*; D006220:Haloperidol / Q000009:adverse effects* / Q000037:antagonists & inhibitors; D006801:Humans; D008297:Male; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000188:drug therapy
D001570:Benzodiazepinones; D002998:Clonazepam; D001418:Baclofen; D006220:Haloperidol