[The fate of the patient with deep vein thrombosis].
Late results in 278 consecutive patients with unilateral deep vein thrombosis treated with streptokinase or heparin/dicoumarol were analysed as to mortality rate, recurrent thrombo-embolism and incidence of postthrombotic syndrome (PTS). The five-year mortality rate was three times as high as that of the age-matched population. The overall mortality rate was 16%, more than half the patients dying of tumour, males largely of gastric or bronchial carcinoma, females of urogenital carcinoma. Thrombo-embolism had recurred in 14% of 204 patients who had been re-examined, in 9% thrombosis, in 3% pulmonary embolism, and in 2% both. A PTS without ulcer had developed in 16%, an ulcer in 8%. The PTS incidence correlated with the original extent of the thrombosis: no PTS if the thrombosis had been confined to the lower-leg axis, but 34% after four-level thrombosis. The data confirm the importance of thrombo-embolism prophylaxis, early diagnosis and subsequent treatment with anticoagulants and compression.
D000328:Adult; D000368:Aged; D003374:Coumarins / Q000627:therapeutic use; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D011655:Pulmonary Embolism / Q000209:etiology; D012008:Recurrence; D013300:Streptokinase / Q000627:therapeutic use; D013924:Thrombophlebitis / Q000150:complications / Q000188:drug therapy / Q000401:mortality*
D003374:Coumarins; D006493:Heparin; D013300:Streptokinase
Zum Schicksal des Patienten mit tiefer Venenthrombose.