Organophosphate insecticide poisoning.
Organophosphate insecticides are widely used agents which are quickly absorbed through the skin and mucous membranes. The effects of acute exposure to these agents can be severe and intensive therapy may be required. Specific drugs are available to reverse the muscarinic, nicotinic and central effects of these poisons. When given early they are very effective and early diagnosis and treatment may therefore be life-saving. A case of acute poisoning with an organophosphate anticholinesterase insecticide is reported. The signs and symptoms of acute poisoning are described and a rational approach to specific treatment is discussed.
D000208:Acute Disease; D000328:Adult; D001285:Atropine / Q000627:therapeutic use; D002801:Cholinesterase Reactivators / Q000627:therapeutic use; D003422:Critical Care; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D062025:Organophosphate Poisoning; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds / Q000506:poisoning*; D011220:Pralidoxime Compounds / Q000627:therapeutic use
D002801:Cholinesterase Reactivators; D007306:Insecticides; D063086:Organothiophosphates; D009946:Organothiophosphorus Compounds; D011220:Pralidoxime Compounds; D001285:Atropine; C030064:demeton-S-methyl; C028797:pralidoxime