Establishment of an epithelial cell line originating from leg skin of a patient with palatine carcinoma.
An epithelial cell line was established from the leg skin of a patient with palatine carcinoma. On the basis of the studies of biological characteristics, such as rapid cell growth, neoplastic morphology, a large group B marker chromosome, the ability of the transplanted cells to produce tumor nodes in Wistar newborn rat, the cell possessing the structure of low differentiated squamous carcinoma and skin-like tissue, etc., we conclude that the PcaSE-1 cell line is an abnormal epithelium cell line.
D000230:Adenocarcinoma / Q000235:genetics / Q000473:pathology*; D000328:Adult; D000818:Animals; D002460:Cell Line; D002869:Chromosome Aberrations; D002905:Chromosomes, Human, 4-5; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008297:Male; D009368:Neoplasm Transplantation; D010157:Palatal Neoplasms / Q000235:genetics / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000473:pathology*