The relation of sodium transport to blood pressure in the adrenalectomized rat.
The effects of treatment of the adrenalectomized rat with aldosterone or corticosterone were observed daily for 3 days. Blood pressure and plasma electrolytes were normalized within 24 h but cell Na and K remained essentially unchanged throughout. We conclude that blood pressure is associated with Na transport activity rather than with cell [Na].
D000315:Adrenalectomy; D000450:Aldosterone / Q000494:pharmacology; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D003345:Corticosterone / Q000494:pharmacology; D004912:Erythrocytes / Q000378:metabolism*; D011188:Potassium / Q000097:blood; D051381:Rats; D012964:Sodium / Q000097:blood*
D000450:Aldosterone; D012964:Sodium; D011188:Potassium; D003345:Corticosterone