Two different variants of the same tropomyosin polypeptide in clones from GM1386 human skin fibroblasts.
A new protein observed in two-dimensional electrophoresis patterns of proteins from the human skin fibroblast line GM1386 has been identified as a charge and molecular-weight variant of the type of tropomyosin found in smooth muscle (Tm:3). This is the second variant of Tm:3 found in GM1386 and represents a second site mutation in one of the genes coding for Tm:3.
D002999:Clone Cells / Q000378:metabolism; D004586:Electrophoresis; D005347:Fibroblasts / Q000378:metabolism; D014644:Genetic Variation; D006801:Humans; D009154:Mutation; D010446:Peptide Fragments / Q000302:isolation & purification; D012867:Skin / Q000378:metabolism*; D014335:Tropomyosin / Q000235:genetics* / Q000302:isolation & purification
D010446:Peptide Fragments; D014335:Tropomyosin