Vasoactive intestinal polypeptide in the hyper-reflexic neuropathic bladder.
The distribution of nerves containing vasoactive intestinal polypeptide (VIP) in the hyper-reflexic neuropathic bladder was investigated using immunocytochemistry and radioimmunoassay. Biopsy specimens were taken from the bladders of 21 patients with urodynamically proven detrusor hyper-reflexia and from 20 control patients with no urodynamic abnormality. The results showed a reduction in the number of VIP immunoreactive nerves and a reduction in VIP concentration in the hyper-reflexic bladder when compared with control samples.
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012021:Reflex, Abnormal / Q000378:metabolism* / Q000473:pathology; D001743:Urinary Bladder / Q000032:analysis / Q000294:innervation; D001750:Urinary Bladder, Neurogenic / Q000378:metabolism* / Q000473:pathology; D014660:Vasoactive Intestinal Peptide / Q000032:analysis*
D014660:Vasoactive Intestinal Peptide