[Sensitization of the leukocytes of stomach cancer patients to extracts of the tumor].
The parallel LAI-tests using tumor cell (Tu) and normal mucosa (Muc) extracts were run in cases of gastric carcinoma (110), benign lesions of the stomach (46) and healthy controls (33). A high incidence (37-43%) of positive reactions in mucosa extract series was observed in both groups of patients. Four possible types of the response were analysed: Tu + Muc+, Tu--Muc--, Tu+Muc- and Tu--Muc+. The peak of Tu--Muc+ type reactivity was observed at stage III of the disease (p less than 0.05). Response to Tu extracts only (Tu+Muc--) was registered mainly in cancer patients but never occurred in the benign group. The best prognosis was observed in cases of Tu+Muc+ type response (p less than 0.02).
D005753:Gastric Mucosa / Q000276:immunology; D006801:Humans; D007114:Immunization; D007957:Leukocyte Adherence Inhibition Test; D007962:Leukocytes / Q000276:immunology*; D013272:Stomach Diseases / Q000276:immunology; D013274:Stomach Neoplasms / Q000276:immunology* / Q000401:mortality; D014020:Tissue Extracts / Q000276:immunology*
D014020:Tissue Extracts
Sensibilizatsiia leĭkotsitov bol'nykh rakom zheludka k ékstraktam opukholi.