Isolation of Acanthamoeba culbertsoni from a patient with meningitis.
A case of amoebic meningitis, presumably primary, was encountered in the Christian Medical College Hospital, Vellore, South India, in November 1983. The patient, a 40-year-old man, had cerebrospinal fluid rhinorrhea before the meningitis developed. Acanthamoeba culbertsoni was repeatedly demonstrated in and cultured from the cerebrospinal fluid. The patient responded dramatically to a combination therapy of penicillin and chloramphenicol.
D000328:Adult; D000562:Amebiasis / Q000188:drug therapy; D000818:Animals; D005500:Follow-Up Studies; D006249:Hartmannella / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008581:Meningitis / Q000188:drug therapy / Q000469:parasitology*; D051379:Mice