[Behavior of serum acid levels in children in comparison with adults and the incidence of purine metabolism disorders and concomitant diseases in children of families with gout].
The result of our examinations was that there is a vast correspondence of the medium levels of serum uric acid as well as of the frequency of hyperuricaemia between children after the 10th year of age and the adults. In comparison to the average population children from families with a gout anamnesis revealed a twice as frequent disturbance of the purine metabolism. In a familial appearance of gout and/or in unclear renal as well as joint findings the paediatrician should think of the presence of a disturbance of the purine metabolism.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate; D006073:Gout / Q000097:blood / Q000235:genetics*; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000235:genetics; D007677:Kidney Function Tests; D008297:Male; D010641:Phenotype; D011686:Purine-Pyrimidine Metabolism, Inborn Errors / Q000097:blood / Q000235:genetics*; D011687:Purines / Q000097:blood*; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood*
D011687:Purines; D014280:Triglycerides; D014527:Uric Acid; D002784:Cholesterol
Verhalten des Serumsäurespiegels von Kindern im Vergleich zu Erwachsenen sowie Häufigkeit von Purinstoffwechselstörungen und Begleitkrankheiten bei Kindern aus gichtbelasteten Familien.