Compressibility of anhydrous tricalcium phosphate.
It is shown that tricalcium phosphate follows a simple Heckel relationship in pressures of usual tablet compression, only if a density of 1.92 g/mL is used. This coincides with the density obtained by wet pycnometry, whereas the crystallographical density is 3.1 g/mL. The interpretation is that some of the pore space is occluded and does not constitute a part of the Heckel pore space.
D002130:Calcium Phosphates; D003460:Crystallization; D004339:Drug Compounding; D013607:Tablets
D002130:Calcium Phosphates; D013607:Tablets; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous