Energy metabolism of the developing brain.
Cerebral metabolism in utero and in the neonatal period remains incompletely understood. A major investigative technique uses 14C deoxyglucose. Species differences, behavioral states and gestational age all have an impact. Hormonal and sensory stimuli have potential influences. The use of this new investigative technique in the human will allow detailed study of the effects of a variety of pathophysiologic events and possibly of drug therapy on cerebral glucose metabolism.
D000818:Animals; D001345:Autoradiography; D001921:Brain / Q000196:embryology* / Q000378:metabolism; D002250:Carbon Radioisotopes; D002560:Cerebrovascular Circulation; D003847:Deoxyglucose; D004734:Energy Metabolism; D005260:Female; D005865:Gestational Age; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D011247:Pregnancy; D012756:Sheep / Q000196:embryology; D013045:Species Specificity
D002250:Carbon Radioisotopes; D003847:Deoxyglucose; D005947:Glucose