Identification of calcium-binding proteins associated with the lymphocyte plasma membrane.
The Nonidet P40 insoluble fraction of lymphocyte plasma membrane contains three polypeptides of about 68,000-, 33,000- and 28,000-Mr which are solubilised by Ca2+-chelators. As judged by various criteria the 33,000-Mr polypeptide is homologous to the 36,000-Mr pp60src kinase substrate of chicken fibroblasts and the 68,000-Mr polypeptide is related to the 67,000-Mr "calelectrin" of bovine liver. The 28,000-Mr polypeptide may also be related to calelectrin.
D000818:Animals; D002135:Calcium-Binding Proteins / Q000097:blood*; D002460:Cell Line; D002462:Cell Membrane / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007422:Intestines / Q000032:analysis; D007700:Kinetics; D008099:Liver / Q000032:analysis; D008214:Lymphocytes / Q000032:analysis*; D008565:Membrane Proteins / Q000032:analysis; D051379:Mice; D008970:Molecular Weight; D013552:Swine
D002135:Calcium-Binding Proteins; D008565:Membrane Proteins