Evaluation of a new germicidal hand creme.
A new germicidal hand creme (Wash & Heal, Med-Chem Labs, Okemos, MI) was evaluated for its ability to reduce bacterial levels on the hands. Colony counts of coagulase-negative staphylococci were significantly reduced immediately after use, with notable antimicrobial activity present for the next 90-120 minutes. The germicidal creme was more active against staphylococci than gram negative bacilli. The creme's germicidal activity occurred rapidly and was targeted against gram positive cocci found on the skin; whereas the bar soap's activity occurred more slowly and had a broader target. This creme could be used between hand washings to further reduce microbial flora of the hands.
D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D004202:Disinfectants; D004304:Dosage Forms; D004341:Drug Evaluation; D005989:Glycerides / Q000494:pharmacology*; D006225:Hand / Q000382:microbiology*; D006235:Hand Disinfection; D006801:Humans; D007848:Laurates / Q000494:pharmacology*; D007850:Lauric Acids / Q000494:pharmacology*; D050178:Monoglycerides; D012867:Skin / Q000382:microbiology
D004202:Disinfectants; D004304:Dosage Forms; D005989:Glycerides; D007848:Laurates; D007850:Lauric Acids; D050178:Monoglycerides; C020777:monolaurin