Malignant rhabdoid tumor of the heart in an infant.
A 6-month-old infant presenting with pericardial effusion was found to have a malignant rhabdoid tumor of the heart. As visualized by two-dimensional echocardiography and subsequently by contrast-enhanced computerized axial tomographic scanning, the tumor arose from the left ventricular free wall and grew into the pericardial space. Despite two courses of single-agent chemotherapy with doxorubicin, the child died 3 months later. This is the first reported case of malignant rhabdoid tumor of the heart, and the fifth case of a primary cardiac malignancy in an infant.
D006328:Cardiac Catheterization; D004317:Doxorubicin / Q000627:therapeutic use; D004452:Echocardiography / Q000379:methods; D004562:Electrocardiography; D005260:Female; D006338:Heart Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D007223:Infant; D008207:Lymphatic Metastasis; D014057:Tomography, X-Ray Computed
D004317:Doxorubicin