[Changes in the blood surface-active properties during the correction of hemorheological disorders in patients with occlusive lesions of the abdominal aorta and arteries of the extremities].
Significant hemorheologic disorders were demonstrated in 68 patients with Leriche's syndrome and 50 patients with Raynaud's disease, as compared to 42 normal controls. Plasma and erythrocyte membrane surface tension (ST) was measured, using a surface balance, in 29 patients with Leriche's syndrome, 26 patients with Raynaud's disease and 24 normal subjects. In both kinds of vascular abnormality, major parameters of erythrocyte membrane adsorption film ST remained unchanged, yet the areas of their adsorption hysteresis loops increased. In patients with Raynaud's disease, the minimal plasma ST increased, while the stability index and the hysteresis loop area declined. In patients with Leriche's syndrome, those were unchanged. The control of hemorheologic disorders by moderate hemodilution using albumin, rheopolyglucin, antiaggregants and fibrinolytic agents resulted in the normalization of plasma ST parameters in Raynaud's disease, and a greater hysteresis loop area in both kinds of vascular disease. Major parameters of erythrocyte membrane adsorption film ST remained unchanged, while the area of their hysteresis loops decreased.
D000328:Adult; D001012:Aorta, Abdominal; D001018:Aortic Diseases / Q000097:blood* / Q000628:therapy; D001157:Arterial Occlusive Diseases / Q000097:blood* / Q000628:therapy; D001809:Blood Viscosity; D003131:Combined Modality Therapy; D004910:Erythrocyte Membrane / Q000502:physiology; D006801:Humans; D007866:Leg / Q000098:blood supply*; D007925:Leriche Syndrome / Q000097:blood / Q000628:therapy; D008297:Male; D010949:Plasma / Q000502:physiology; D011928:Raynaud Disease / Q000097:blood / Q000628:therapy; D013500:Surface Tension
Izmenenie poverkhnostno-aktivnykh svoĭstv krovi pri korrektsii gemoreologicheskikh narusheniĭ u bol'nykh s okkliuziruiushchimi porazheniiami briushnoĭ aorty i arteriĭ konechnosteĭ.