Nitrous oxide and wound healing.
Following a paravertebral surgical incision, mature, female rats under ether anaesthesia were exposed to either 3% nitrous oxide, continuously for 48 h, or 50% nitrous oxide, 4 h each day for 7 days. For each exposure group, a similar number of rats was exposed to atmospheres containing no nitrous oxide. Wound healing was assessed by measurement of the breaking strengths of wound samples. No statistically significant influence on breaking strength could be attributed to nitrous oxide following either exposure sequence.
D000818:Animals; D005260:Female; D009609:Nitrous Oxide / Q000494:pharmacology*; D051381:Rats; D013718:Tensile Strength / Q000187:drug effects; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects*
D009609:Nitrous Oxide