Theoretical investigations of laser thermal retinal injury.
A thermal damage model including heat conduction for retinal lesions is described to explain thermal threshold damage and compare it to experimental values in the regime of 1 ms to 300 ms. With the aid of these model calculations unspecific thermal damage (denaturation of proteins) could be separated from thermally induced damage to the photoreceptors. Furthermore, the thermal model allows an extrapolation to hazards to the fundus from intense light irradiation that have not been investigated experimentally.
D000818:Animals; D005136:Eye Proteins; D006358:Hot Temperature / Q000009:adverse effects*; D007834:Lasers / Q000009:adverse effects*; D008251:Macaca; D008433:Mathematics; D008954:Models, Biological; D011489:Protein Denaturation; D011817:Rabbits; D012160:Retina / Q000293:injuries*
D005136:Eye Proteins