Chronic granulomatous disease associated with chronic glomerulonephritis.
A boy with chronic granulomatous disease (CGD) developed glomerulonephritis at the age of 12 years. The glomerulonephritis progressed to terminal uraemia at age 15 when maintenance haemodialysis was started. The clinical course was complicated by pulmonary aspergillosis and Pseudomonas septicaemia from which he eventually died. The glomerulonephritis was of unknown origin, and a possible relationship between CGD and glomerulonephritis is discussed.
D000293:Adolescent; D001344:Autopsy; D002908:Chronic Disease; D005921:Glomerulonephritis / Q000209:etiology* / Q000473:pathology; D006098:Granulocytes / Q000473:pathology; D006105:Granulomatous Disease, Chronic / Q000150:complications*; D006801:Humans; D007668:Kidney / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000209:etiology; D008297:Male; D011552:Pseudomonas Infections / Q000209:etiology; D018805:Sepsis / Q000209:etiology; D014511:Uremia / Q000209:etiology