Anticonvulsive properties of newly-synthesized indenoimidazolediones.
We have synthesized and tested a series of derivatives of indenoimidazoledione and found that they can protect mice from seizures induced by pentylenetetrazol (Metrazol).
D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects; D007093:Imidazoles / Q000494:pharmacology*; D007192:Indenes / Q000494:pharmacology*; D051379:Mice; D010433:Pentylenetetrazole; D012640:Seizures / Q000517:prevention & control
D000927:Anticonvulsants; D007093:Imidazoles; D007192:Indenes; D010433:Pentylenetetrazole