Metacarpophalangeal pattern profile analysis in Sotos syndrome.
The metacarpophalangeal pattern profile (MCPP) was analyzed on 16 Sotos syndrome patients. A mean Sotos syndrome profile was produced. Correlation studies confirm clinical homogeneity of Sotos syndrome individuals. Discriminant analysis of Sotos syndrome patients and normal individuals produces a function of two MCPP variables and age, which may provide a useful tool for diagnosis.
D000293:Adolescent; D002648:Child; D005260:Female; D005385:Fingers / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D005877:Gigantism / Q000000981:diagnostic imaging* / Q000235:genetics; D006225:Hand / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008663:Metacarpus / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D011859:Radiography; D013577:Syndrome