An epizootic form of Tyzzer's disease in a rat colony.
An epizootic form of Tyzzer's disease was experienced in a rearing facility of laboratory rats with an infectivity and morbidity of 36 to 80% and 5 to 30%, respectively. With liver tissue from an affected rat, a spore-forming causative agent was successfully transmitted to other rats by oral inoculation in association with cortisone, producing 10(6) to 10(7) spores/g liver tissue.
D000818:Animals; D001424:Bacterial Infections / Q000453:epidemiology / Q000662:veterinary*; D003348:Cortisone / Q000494:pharmacology; D004196:Disease Outbreaks / Q000662:veterinary*; D007564:Japan; D008099:Liver / Q000382:microbiology; D051381:Rats; D011919:Rats, Inbred Strains; D012376:Rodent Diseases / Q000453:epidemiology*; D013171:Spores, Bacterial
D003348:Cortisone