Chelation therapy in children as treatment of sequelae in severe lead toxicity.
Certain children who experience a toxic lead episode requiring hospitalization in infancy or early childhood will manifest central nervous system dysfunctions, including hyperactivity, as sequelae of this experience. In this study, findings indicate that persistent, higher-than-normal lead levels, dating back to the time of the initial toxicity, may well be a mechanism underlying some of these sequelae. Consequently, some part of these sequelae may be preventable and/or treatable.
D002648:Child; D002652:Child Behavior; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000097:blood / Q000188:drug therapy / Q000209:etiology; D007854:Lead / Q000097:blood*; D007855:Lead Poisoning / Q000150:complications / Q000188:drug therapy*; D008297:Male; D010396:Penicillamine / Q000627:therapeutic use; D011795:Surveys and Questionnaires
D007854:Lead; D010396:Penicillamine