Electrophysiological measurement of glucose uptake into motor nerve terminals of mature adult and aged rats.
Glucose uptake into motor nerve terminals innervating the extensor digitorum longus (EDL), diaphragm and soleus, was monitored indirectly in mature adult and aged rats by recording changes in quantal transmitter release induced by glucose. Glucose entered the nerve terminals innervating the EDL more rapidly than either the diaphragm or the soleus. There was an age-related decrease in glucose uptake into the nerve terminals innervating all 3 muscles, although this change was not significant statistically.
D000367:Age Factors; D000818:Animals; D005947:Glucose / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D008564:Membrane Potentials; D009045:Motor Endplate / Q000502:physiology; D009132:Muscles / Q000294:innervation; D009469:Neuromuscular Junction / Q000378:metabolism*; D009928:Organ Specificity; D051381:Rats; D011916:Rats, Inbred F344
D005947:Glucose