Hypopituitarism and septooptic "dysplasia" in first cousins.
Although familial forms of hypopituitarism are known, to our knowledge familial septooptic "dysplasia" in association with hypopituitarism has not been reported. We describe two first cousins with panhypopituitarism, one of whom had septooptic dysplasia. We discuss the possibility that septooptic dysplasia-hypopituitarism may be inherited as an autosomal dominant, or recessive, or multifactorial trait.
D000328:Adult; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000235:genetics*; D007231:Infant, Newborn; D008297:Male; D009900:Optic Nerve / Q000002:abnormalities*; D010375:Pedigree; D012688:Septum Pellucidum / Q000002:abnormalities; D013577:Syndrome