Effect of human urinary extract on initiation and growth of spontaneous murine mammary tumours.
A material with gonadotrophin-inhibiting properties was extracted from pooled human urine of male subjects. This material was able to prevent initiation of mammary tumour growth in C3H(Jax) mice. When injected into tumour-bearing animals, 5 out of 31 tumours regressed while 21 out of 31 tumours stopped growing.
D000230:Adenocarcinoma / Q000188:drug therapy*; D000818:Animals; D005260:Female; D006023:Glycoproteins / Q000627:therapeutic use*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000188:drug therapy*; D051379:Mice; D008809:Mice, Inbred C3H
D006023:Glycoproteins; C014995:gonadotropin inhibitor