Freeze-fracture analysis of the muscle fiber plasma membrane in Duchenne dystrophy.
The intramembrane particle density in freeze-fractured muscle fiber plasma membranes did not differ in 4 patients with Duchenne dystrophy and 4 normal subjects. However, we confirmed reported loss of orthogonal arrays and increased density of caveolae in dystrophic muscle.
D002462:Cell Membrane / Q000648:ultrastructure; D002648:Child; D002675:Child, Preschool; D005614:Freeze Fracturing; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000473:pathology*; D009136:Muscular Dystrophies / Q000473:pathology*