[Effect of short duration euphylline infusion on the uteroplacental blood pool].
In 19 late pregnant women with suspected placental insufficiency uteroplacental perfusion was measured and then the effect of a shortlasting infusion of aminophyllin on uteroplacental blood pool was examined. The results show evidence that in normal perfusion typ uteroplacental blood flow is not influenced by aminophyllin. But in pathologic perfusion typs there are two groups after aminophyllin. In the first one there is an increase of activity measured over the placenta (positive test). In these cases the cause of the lowered perfusion may be a functional one, treatment will be successful. In the second group there was no change or a decreasing activity following administration of aminophyllin (negative test). In these cases the reduced perfusion may be caused by morphological factors. Treatment will be without success with a high likelihood. The aminophyllintest following the isotope perfusion measurement is useful both for prognosis of newborn weight and appropriateness of therapy.
D000628:Aminophylline / Q000627:therapeutic use*; D001724:Birth Weight / Q000187:drug effects; D005260:Female; D005317:Fetal Growth Retardation / Q000188:drug therapy; D006801:Humans; D007231:Infant, Newborn; D007263:Infusions, Parenteral; D008431:Maternal-Fetal Exchange / Q000187:drug effects*; D010920:Placenta / Q000098:blood supply*; D010927:Placental Insufficiency / Q000188:drug therapy; D011247:Pregnancy; D011379:Prognosis; D012039:Regional Blood Flow / Q000187:drug effects; D014599:Uterus / Q000098:blood supply*
D000628:Aminophylline
Die Wirkung einer kurzdauernden Euphyllin-Infusion auf den uteroplazentaren Blutpool.