[Detection of HBsAg in the familial environment of children with viral hepatitis B].
A total of 231 persons from the families of 62 children hospitalized in connection with viral hepatitis B were examined for the presence of HBsAg in their blood over a period of 3 years. Simultaneously with countercurrent electrophoresis (CIE) and the gel precipitation (GP) test, the passive hemagglutination (PHA) test and the GP test with sandwich treatment were used in this work. The presence of HBs-antigenemia in the members of the families of children with viral hepatitis confirmed by laboratory methods were found to occur 6.7 times more frequently than in the families of children with HBsAg-negative hepatitis. The use of the PHA test and the GP test with sandwich treatment increased the frequency of the detection of HBsAg 2.5 times in comparison with CIE and the GP test. The data indicating the possibility of children being infected through everyday contacts in families with cases of HBs-antigenemia among their members are presented, but further studies are necessary to make the final decision on this problem.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004197:Disease Reservoirs; D005260:Female; D006509:Hepatitis B / Q000235:genetics / Q000276:immunology* / Q000635:transmission; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D007223:Infant; D008297:Male
D006514:Hepatitis B Surface Antigens
Vyiavlenie HBsAg v semeĭnom okruzhenii deteĭ, bol'nykh virusnym gepatitom B.