[Persistent pupillary membranes in a cynomolgus monkey].
Three thousand and five apparently healthy cynomolgus monkeys (Macaca fascicularis) were examined for the finding of the anterior part of the oculi by using an ophthalmoscope. One drop of the mixed solution of 0.5% tropicamide and 0.5% phenylephrine hydrochloride was instilled into each eye of the animal. Then, those monkeys were anesthetized with ketamine-HC1 at the dose level of 10 mg/kg B. W.. One monkey had opaque membranes of tan to brown color, extending from some part of collarette of the iris to the other part of collarette like the network over the pupil. This finding was diagnosed to be bilateral persistent pupillary membranes. Further breeding studies will be carried to determine if this case in hereditary.
D000818:Animals; D008251:Macaca; D008252:Macaca fascicularis; D008992:Monkey Diseases / Q000151:congenital* / Q000473:pathology; D011680:Pupil / Q000002:abnormalities*