[Ulcerative dermatitis (pyoderma gangrenosum) with selective IgA deficiency and development of an oral carcinoma].
17 years ago, selective IgA deficiency was diagnosed in a 45-year-old woman suffering from dermatitis ulcerosa. In 1984, this patient developed oral cancer with metastases in the regional lymph nodes. Her long-term history of nicotine and alcohol abuse in combination with IgA deficiency seemed to be a risk factor for oral malignancy.
D000437:Alcoholism / Q000150:complications; D004406:Dysgammaglobulinemia / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000209:etiology; D009538:Nicotine; D011711:Pyoderma / Q000150:complications / Q000175:diagnosis*; D012306:Risk; D012883:Skin Ulcer / Q000150:complications / Q000175:diagnosis*; D019966:Substance-Related Disorders
D009538:Nicotine
Dermatitis ulcerosa (Pyoderma gangraenosum) mit selektivem IgA-Mangel und Auftreten eines Mundbodenkarzinoms.