Chemical modifications of the aliphatic bridge of ansamycins. 2. Synthesis and activity of 23-epi-25-deacetylrifamycin S.
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000201:enzymology; D001665:Binding Sites; D001952:Bridged-Ring Compounds; D055598:Chemical Phenomena; D002621:Chemistry; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors; D006900:Hydroxylation; D047029:Lactams, Macrocyclic; D009682:Magnetic Resonance Spectroscopy; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D001952:Bridged-Ring Compounds; D047029:Lactams, Macrocyclic; D012321:DNA-Directed RNA Polymerases