[Drugs inhibiting complement activation].
Complement may be activated by anaesthetic agents as well as contrast media, and so could anaphylactoid reactions be induced. Efficient and harmless complement blocking agents were still lacking. The only agents actually used by anaesthetists were steroids and/or antifibrinolytic drugs. Other agents were not indicated in surgical patients because of their adverse effects and the impossibility of giving them by the intravenous route.
D000305:Adrenal Cortex Hormones / Q000494:pharmacology; D000758:Anesthesia / Q000009:adverse effects; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000933:Antifibrinolytic Agents / Q000494:pharmacology; D003167:Complement Activation / Q000187:drug effects*; D004342:Drug Hypersensitivity / Q000517:prevention & control; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006801:Humans; D011229:Preanesthetic Medication
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D000933:Antifibrinolytic Agents; D004791:Enzyme Inhibitors
Médicaments inhibant l'activation du complément.