Changes in copper and zinc in chronic haemodialysis patients.
We studied the behaviour of copper (Cu) and zinc (Zn) during haemodialysis (HD) in 65 chronic renal failure patients. Serum Cu, Zn and total protein were measured before and after dialysis. The dialyser membrane contained Cu and Zn. However, when the dialyser was washed with normal saline, Zn was removed, while Cu was liberated from the membrane during HD. We conclude that during HD serum Cu and Zn concentrations increased significantly (p less than 0.01), Cu from 98 to 120 micrograms/dl by haemoconcentration and liberation from the membrane, and Zn from 78 to 91 micrograms/dl by haemoconcentration.
D000328:Adult; D003300:Copper / Q000097:blood*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D015032:Zinc / Q000097:blood*
D003300:Copper; D015032:Zinc