[Modeling of myocardial lesions of varying degrees of manifestation].
Five variants of myocardial lesions of different degree were simulated in experiments on 8 dogs, 61 rabbits and 30 rats, namely micronecrosis, diffuse myocarditis, focal dystrophy, small- and large-focal myocardial infarction. The experimental models of heart lesions can be used for studying the pathophysiological mechanisms in cardiac pathology and evaluation of the therapeutic efficacy of new drugs in experimental pharmacology.
D000818:Animals; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000188:drug therapy; D004195:Disease Models, Animal; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D004562:Electrocardiography; D005260:Female; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced / Q000188:drug therapy; D009205:Myocarditis / Q000139:chemically induced / Q000188:drug therapy; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D011817:Rabbits; D051381:Rats
Modelirovanie porazheniĭ miokarda razlichnoĭ stepeni vyrazhennosti.