On the structure of native small ribosomal subunits and initiation factor eIF-3 isolated from rat liver.
The three-dimensional structure of initiation factor eIF-3 and its binding site on native small ribosomal subunits have been analyzed by electron microscopic studies of native small ribosomal subunits and of initiation factor eIF-3 prepared from rat liver as well as by hydrodynamic studies of isolated eIF-3. Initiation factor eIF-3 has the shape of a flat triangular prism and is bound with its triangular base to the body part of the convex rear side of the small ribosomal subunit.
D000818:Animals; D039621:Eukaryotic Initiation Factor-3; D066298:In Vitro Techniques; D008099:Liver / Q000378:metabolism* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008970:Molecular Weight; D010448:Peptide Initiation Factors / Q000302:isolation & purification / Q000378:metabolism*; D011189:Potassium Chloride / Q000494:pharmacology; D051381:Rats; D012270:Ribosomes / Q000378:metabolism* / Q000648:ultrastructure
D039621:Eukaryotic Initiation Factor-3; D010448:Peptide Initiation Factors; D011189:Potassium Chloride