[Uteroplacental circulation and functional status of the fetoplacental unit in risk pregnancies with special reference to late gestosis].
Trial to define position and variability of radioisotope functional diagnostics of placental perfusion in comparison with urinary estrogen excretion by serial examinations. - In case of placental insufficiency estrogen values are significantly reduced starting from the 32nd to 35th gestational week as compared with normal values. In general, placenta perfusion shows delayed half-life periods of the increase in activity in all risk pregnancies beginning from the 28th week of pregnancy. A direct correlation between estrogen values and placenta perfusion can only be detected in cases of chronic placental insufficiency with intrauterine growth retardation. A prolonged perfusion time reveals a fetal hypotrophy in 53% of the cases. Late gestosis takes the first place about all risk pregnancies, connected with placental insufficiency in 30% of the cases. The tendency towards a development of placental insufficiency can be early detected by determination of placental perfusion time.
D004967:Estrogens / Q000652:urine; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology; D005865:Gestational Age; D006439:Hemodynamics; D006801:Humans; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000098:blood supply*; D010927:Placental Insufficiency / Q000503:physiopathology; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D011272:Pregnancy, Multiple; D012306:Risk; D014599:Uterus / Q000098:blood supply*
D004967:Estrogens
Uteroplazentare Durchblutung und Funktionszustand der fetoplazentaren Einheit bei Risikoschwangeren unter besonderer Berücksichtigung der Spätgestose.