Salivary flow in borderline hypertension.
Salivary flow was studied in normotensives and in subjects with hypertension. Salivary flow rate was lower in borderline hypertensives than in normotensives. Propranolol, phentolamine and noradrenaline had no influence on salivary flow. Atropine decreased this parameter. The stimulating effect of neostigmine on saliva production was more pronounced in normotensives than in borderline hypertensives. The data support the assumption that in subjects with borderline hypertension the parasympathetic influence on the salivary glands is reduced.
D000328:Adult; D001285:Atropine / Q000494:pharmacology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D009388:Neostigmine / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D010646:Phentolamine / Q000494:pharmacology; D011188:Potassium / Q000032:analysis; D011433:Propranolol / Q000494:pharmacology; D012463:Saliva / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D012964:Sodium / Q000032:analysis
D009388:Neostigmine; D001285:Atropine; D012964:Sodium; D011433:Propranolol; D011188:Potassium; D009638:Norepinephrine; D010646:Phentolamine