[Microbial flora of the cervix from rupture of the membranes and the antibacterial effect of amniotic fluid].
The endocervical flora was examined in 20 with rupture of membranes, 20 pregnant women served as control. The isolated organisms were aerobic and anaerobic in both groups, whereas P. cepacia was common in group of rupture of membranes, but another microorganisms were not statistically significant. Culture specimens taken from the vagina in nonpregnant women showed a higher presence of total bacteria than did those in pregnant women. The MICs of ampicillin (ABPC) were measured against isolated aerobic organisms from rupture of membranes. The distribution of sensitivity of Bacillus sp. was 0.20 microgram/ml, but another organisms were inhibited in concentration of higher than 3.13 micrograms/ml. The antibacterial effect of amniotic fluid during 24 weeks of gestation on S. aureus and S. pyogenes, but during 34 to 39 weeks of gestation the amniotic fluid has inhibitory effect only on the growth of K. pneumoniae. In contrast, the growth of E. coli was not inhibited by amniotic fluid during 24 to 39 weeks of gestation.
D000653:Amniotic Fluid / Q000502:physiology*; D001419:Bacteria / Q000254:growth & development*; D002584:Cervix Uteri / Q000382:microbiology*; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000382:microbiology*; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third