Cholecystokinin octapeptide-like immunoreactive material in neurons of the intralaminar nuclei of the cat's thalamus.
Cholecystokinin-like immunoreactive material (CCK-IR) was revealed in the cat's thalamus by using the peroxidase-antiperoxidase method. The most dense collection of perikarya containing CCK-IR was seen in the rostral group of the intralaminar nuclei, in rostral parts of the rhomboid nucleus and the anterodorsal nucleus. Cells with CCK-IR were also found in the caudal group of the intralaminar nuclei, in the paraventricular nucleus and the parataenial nucleus. The remaining thalamic nuclei were void of CCK-IR. By combining immunohistochemistry with retrograde transport of horseradish peroxidase, CCK-IR was shown to be present in neurons of the intralaminar nuclei projecting to the neocortex. Our findings suggest that CCK might act as a transmitter in the efferent projections of the intralaminar and midline nuclei of the cat's thalamus.
D000679:Amygdala / Q000276:immunology; D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000276:immunology; D003712:Dendrites / Q000648:ultrastructure; D006624:Hippocampus / Q000276:immunology; D006651:Histocytochemistry; D007120:Immunochemistry; D009474:Neurons / Q000276:immunology; D012844:Sincalide / Q000276:immunology*; D013787:Thalamic Nuclei / Q000166:cytology / Q000276:immunology* / Q000648:ultrastructure; D014018:Tissue Distribution
D012844:Sincalide