Short-term kidney preservation: to perfuse or not to perfuse with the new Belzer perfusate.
Delayed graft function is ischaemically induced and the consequence of high energy phosphate depletion. A new perfusate, described by Belzer, has been used in 43 kidney preservations, 16 of which had prolonged cold ischaemia. The overall immediate function rate was 37 of 43 kidneys or 86 per cent. Of 18 kidneys cold-stored during the same period, only nine functioned immediately. Twenty-six of these patients received cyclosporine for immunosuppression without an increase in delayed graft function or evidence of increased nephrotoxicity because of ischaemic injury or prolonged preservation.
D000255:Adenosine Triphosphate / Q000378:metabolism; D003080:Cold Temperature; D006801:Humans; D066298:In Vitro Techniques; D007668:Kidney / Q000378:metabolism; D009926:Organ Preservation / Q000379:methods*; D010477:Perfusion
D000255:Adenosine Triphosphate