Erratic data in thin layer chromatography due to anomalous behavior of correction standards.
Correction of crude thin layer chromatographic data usually enables a reliable comparison with reference data bases. However, when the correction standards are not spotted in the right positions, the calculation may produce false results if anomalous migration occurs. This was observed in the case of acidic and neutral drugs developed in the chloroform-methanol (9:1) system.
D002855:Chromatography, Thin Layer / Q000592:standards*; D006801:Humans; D008099:Liver / Q000032:analysis; D004364:Pharmaceutical Preparations / Q000097:blood; D012015:Reference Standards
D004364:Pharmaceutical Preparations