Overwhelming post-splenectomy infection with Plesiomonas shigelloides in a patient cured of Hodgkin's disease. A case report.
The immune deficiencies of Hodgkin's disease persist to some degree even after the patients are clinically cured; these may be amplified by loss of splenic immunologic functions after staging laparotomy and splenectomy. The authors submit a case report wherein a bacterium of relatively low virulence, Plesiomonas shigelloides, was associated with a rapidly fulminant septicemia, disseminated intravascular coagulation, Waterhouse-Friderichsen syndrome, and death in a splenectomized patient free of Hodgkin's disease for approximately five years. This emphasizes the need for prolonged observation, rapid diagnosis, and aggressive intervention in immunocompromised patients, especially those supposedly cured of previous hematologic malignancy.
D000328:Adult; D001424:Bacterial Infections / Q000209:etiology*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D006689:Hodgkin Disease / Q000150:complications* / Q000601:surgery; D006801:Humans; D008297:Male; D013156:Splenectomy / Q000009:adverse effects*; D014737:Vibrionaceae; D014884:Waterhouse-Friderichsen Syndrome / Q000209:etiology