[Morphometric mitochondrial studies in the placenta of early pregnancies following a normal course of pregnancy and in maternal diabetes mellitus].
89 electron micrographs from a diabetic placenta of the 8th week of pregnancy and from two normal placentas of the same period of gestation are investigated morphometrically. In the trophoblast mitochondria of the diabetic placenta the surface/volume ratio between the surface of the cristae and mitochondrial volume shows a statistically significant reduction as compared to the values in the normal placenta of the same period of gestation. The morphological changes of the placenta are being related to disorders of the regulation of the metabolic processes in diabetes mellitus in early pregnancy.
D001786:Blood Glucose / Q000378:metabolism; D005260:Female; D006801:Humans; D008431:Maternal-Fetal Exchange; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure*; D008933:Mitochondrial Swelling; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011254:Pregnancy in Diabetics / Q000473:pathology*
D001786:Blood Glucose
Morphometrische Mitochondrienuntersuchungen an der Plazenta von Frühschwangerschaften nach normalem Schwangerschaftsverlauf und bei mütterlichem Diabetes mellitus.