Open heart surgery in patients with cold-reactive proteins.
The presence of cold-reactive proteins may pose special hazards to the patient about to undergo hypothermic cardiopulmonary bypass, topical myocardial cooling, and cold potassium cardioplegic arrest. The detection and characterization of such proteins, their potential adverse effects, and a proposed management protocol are discussed.
D000373:Agglutinins / Q000032:analysis*; D000787:Angina Pectoris / Q000276:immunology*; D000789:Angina, Unstable / Q000276:immunology* / Q000503:physiopathology / Q000601:surgery; D001831:Body Temperature; D002315:Cardiopulmonary Bypass; D003450:Cryoglobulins; D004562:Electrocardiography; D006324:Heart Arrest, Induced; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000008:administration & dosage; D017680:Potassium Compounds; D013318:Stroke Volume
D000373:Agglutinins; D003450:Cryoglobulins; D017680:Potassium Compounds; C029443:cold agglutinins; C018369:potassium cardioplegic solution; D011188:Potassium