Thermal inhibition of nociceptor-driven spinal cord neurones in the rat.
The inhibitory effects of cutaneous thermal stimulation have been tested on background and noxious-evoked discharge of neurones in the lumbar spinal cord of anaesthetized rats. Inhibition of background discharges by warming and of noxious-evoked discharges by warming and/or cooling have been demonstrated. Thermal inhibition may be a neural basis for thermal analgesia.
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D005071:Evoked Potentials; D008465:Mechanoreceptors / Q000502:physiology; D009433:Neural Inhibition; D009474:Neurons / Q000502:physiology; D009619:Nociceptors / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000294:innervation*; D013116:Spinal Cord / Q000502:physiology*; D013823:Thermoreceptors / Q000502:physiology*; D013697:Thermosensing / Q000502:physiology