Testing hypotheses about interclass correlations from familial data.
Testing problems concerning interclass correlations from familial data are considered in the case where the number of siblings varies among families. Under the assumption of multivariate normality, two test procedures are proposed for testing the hypothesis that an interclass correlation is equal to a specified value. To compare the properties of the tests, including a likelihood ratio test, Monte Carlo experiments are performed. Several test statistics are derived for testing whether two variables about a parent and child are uncorrelated. The proposed tests are compared with previous test procedures, using Monte Carlo simulation. A general procedure for finding confidence intervals for interclass correlations is also derived.
D000704:Analysis of Variance; D001699:Biometry; D005190:Family; D005826:Genetics, Medical; D006801:Humans; D008957:Models, Genetic; D012107:Research Design; D012959:Socioeconomic Factors