[Determination of 5-methoxypsoralen in suntan cosmetics].
A method for the determination of 5-methoxypsoralene in suntan-cosmetics is described. After liquid chromatographic clean-up, the final extract is screened by twodimensional thin layer chromatography. For positive extracts 5-methoxypsoralene is analysed quantitatively by capillary gas chromatography, using 5-alpha-cholestane as an internal standard and flame ionization detection (FID). The results were confirmed by gas chromatography-mass spectrometry (GC-MS). The recoveries for suntan-cosmetics of emulsion type were 70% and for tanning oils 90%. Detection limits of the method were 0,1 to 0,5 mg/kg, depending on the sample type. By application of this method 5-methoxypsoralene was detected in 6 of the 21 cosmetic products at levels up to 28 mg/kg.
D000078223:5-Methoxypsoralen; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D003358:Cosmetics / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D008730:Methoxsalen / Q000032:analysis*
D003358:Cosmetics; D000078223:5-Methoxypsoralen; D008730:Methoxsalen
Bestimmung von 5-Methoxypsoralen in Sonnenschutzmitteln.