[Cholesterol ester increases the permeability of erythrocyte membrane].
The effect of cholesteryl palmitate on erythrocyte membrane permeability for K+ and hemoglobin was studied. Cholesterol ether was incorporated into the erythrocyte membrane by liposomes containing cholesteryl palmitate and lecithin or by dispersion of cholesteryl palmitate. It was shown that cholesteryl palmitate considerably increases permeability of the erythrocyte membrane for K+ and hemoglobin. The leakage of K+ and hemoglobin from red blood cells is not accompanied by cell destruction.
D000818:Animals; D002463:Cell Membrane Permeability / Q000187:drug effects*; D002788:Cholesterol Esters / Q000378:metabolism / Q000494:pharmacology*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D008081:Liposomes; D011188:Potassium / Q000378:metabolism; D011817:Rabbits
D002788:Cholesterol Esters; D006454:Hemoglobins; D008081:Liposomes; D011188:Potassium
Efir kholesterina uvelichivaet pronitsaemost' membran éritrotsitov.