Central spinal myelinolysis.
A midline lesion of the funiculus gracilis was found in four patients with histories of alcoholism, nutritional disturbance, and repeated episodes of electrolyte imbalance. Histologic and anatomic abnormalities were similar to those of central pontine myelinolysis. Sodium imbalance may play a role in the pathogenesis of both conditions.
D000328:Adult; D000368:Aged; D001369:Axons / Q000648:ultrastructure; D003711:Demyelinating Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009186:Myelin Sheath / Q000473:pathology / Q000648:ultrastructure; D013116:Spinal Cord / Q000473:pathology; D013118:Spinal Cord Diseases / Q000473:pathology*