title: Gonococcal vulvovaginitis among female children in Malaysia.
abstract: In this retrospective review of 16 children with vulvovaginitis due to Neisseria gonorrhoeae, the authors attempt to estimate the incidence of this infection and to ascertain the routes of transmission. From January 1977 to December 1982, 422 cases of gonococcal vulvovaginitis in women of all age groups were encountered at the University Hospital, Kuala Lumpur, Malaysia. Of these, 406 cases (96.2%) occurred in adults, and 16 cases (3.8%) occurred in children younger than 12 years of age. Penicillinase-producing N. gonorrhoeae (PPNG) strains were isolated from five (31%) of the 16 girls; all five cases were subsequently treated with cefuroxime and probenecid. The rest responded to intramuscular procaine penicillin. Although all patients appeared to be cured, only ten of 11 (two with PPNG) had test-of-cure cultures performed after treatment. Although interviewing the parents revealed no history of sexual contact in these children, nine of the girls were linked to culture-positive adult(s).
mesh_terms: D002648:Child; D005260:Female; D006069:Gonorrhea / Q000453:epidemiology* / Q000628:therapy / Q000635:transmission; D006801:Humans; D008296:Malaysia; D012189:Retrospective Studies; D014848:Vulvovaginitis / Q000453:epidemiology* / Q000209:etiology / Q000635:transmission