Effects of abdominal vagotomy on serum LH concentrations in female rats.
Vagotomy on the morning of pro-oestrus did not prevent the pro-oestrous LH surge and rats became oestrous on the following day. However, vagotomized rats then exhibited a period of acyclicity which lasted for 20.4 +/- 1.3 (s.e.m.) days. Food intake and body weight also declined after vagotomy. During the first week after vagotomy, afternoon LH surges generally did not occur, a pattern which was similar in animals pair fed with vagotomized rats. However, pair-fed rats showed oestrous cycles while vagotomized rats were acyclic. At 7 days after vagotomy, LH surges were induced by oestradiol benzoate and progesterone treatment of ovariectomized rats. Vagotomy suppressed the post-ovariectomy increase in serum LH at 7 and 21 days after surgery. These results, combined with those of other studies, suggest impairment of LH release in vagotomized rats.
D000818:Animals; D001835:Body Weight; D002369:Castration; D002149:Energy Intake; D004958:Estradiol / Q000494:pharmacology; D004971:Estrus; D005260:Female; D007986:Luteinizing Hormone / Q000097:blood*; D010053:Ovary / Q000294:innervation; D011247:Pregnancy; D011359:Proestrus; D011374:Progesterone / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D014628:Vagotomy
D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone