[Tracheobronchial clearance in the hypersecreting asthmatic patient].
Tracheo-bronchial clearance in the hyper-secreting asthmatic patient was studied by observing the elimination over a period of time of a tracer placed on the bronchial wall over time. The authors describe the method used. The analysis of the results enables two purification processes to be distinguished: muco-ciliary activity and cough. The reliability of the method enabled comparison of the results obtained in 7 healthy subjects and 11 hyper-secreting asthmatics. In the healthy subjects, clearance is carried out by the muco-ciliary activity. In the asthmatics, global clearance is normal, but the cough plays an essential role as the muco-ciliary activity is decreased. The question then arises as to whether the decreased muco-ciliary activity in asthmatic patients is due to failure of the bronchial cilia or to the mucus.
D000328:Adult; D000336:Aerosols; D001249:Asthma / Q000503:physiopathology*; D001980:Bronchi / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology*; D002923:Cilia / Q000502:physiology; D003371:Cough / Q000503:physiopathology; D005260:Female; D006801:Humans; D007475:Ion Exchange Resins; D008297:Male; D008875:Middle Aged; D009093:Mucus / Q000502:physiology; D011877:Radionuclide Imaging; D013183:Sputum / Q000378:metabolism; D013667:Technetium; D013997:Time Factors; D014132:Trachea / Q000503:physiopathology*
D000336:Aerosols; D007475:Ion Exchange Resins; D013667:Technetium
L'épuration trachéo-bronchique chez l'asthmatique hypersécrétant.