title: [Nuclear medicine demonstration of esophageal bile reflux].
abstract: Biliary and pancreatic juice has been implicated as a cause of regional inflammation or carcinoma after gastric surgery. We studied 38 patients after gastrectomy using a modification of cholescintigraphy (185 mBq 99m-Tc-DESIDA i.v.). As soon as the tracer had reached the duodenum, a dynamic study (30 min, 120 frames) was started. Thereafter a static image of the epigastrium and thorax in the anterior view with more than 1000 cts/cm2 was recorded. This procedure was repeated after a meal. Of 29 patients without complaints only 4 had a reflux into the jejunal loop. By contrast in 7 of 9 patients with suggestive symptoms this examination demonstrated bile reflux which reached the oesophagus in 6 cases. A stenosis of the distal oesophagus prevented oesophageal reflux in one patient. 2 patients with oesophageal reflux had a history of oesophageal stenosis and oesophagitis confirmed by endoscopy. The remaining 2 patients without demonstrable reflux had neither oesophagitis nor radiologically verified reflux. Cholescintigraphy as modified by us may detect clinical relevant bile reflux into the oesophagus. This is important for surgeons selecting patients with potential benefit from a reoperation. Since most patients with complaints after gastrectomy have had demonstrable bile reflux, reflux-reducing surgical techniques should be used in all.
mesh_terms: D001655:Bile Reflux / Q000000981:diagnostic imaging*; D001659:Biliary Tract / Q000000981:diagnostic imaging; D001660:Biliary Tract Diseases / Q000000981:diagnostic imaging*; D004942:Esophagitis, Peptic / Q000000981:diagnostic imaging; D004947:Esophagus / Q000000981:diagnostic imaging; D005743:Gastrectomy; D005764:Gastroesophageal Reflux / Q000000981:diagnostic imaging*; D006801:Humans; D007098:Imino Acids; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013667:Technetium; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid; D019785:Technetium Tc 99m Disofenin; D013997:Time Factors
chemical_list: D007098:Imino Acids; D019784:Technetium Tc 99m Diethyl-iminodiacetic Acid; D013667:Technetium; D019785:Technetium Tc 99m Disofenin
vernacular_title: Nuklearmedizinischer Nachweis des ösophagealen Gallerefluxes.