title: Manual sequence learning after focal cortical lesions.
abstract: Patients with unilateral frontal or temporal excisions and normal control subjects learned sequences of hand positions. Left-frontal and left-temporal lesions impaired learning these sequences. No group had particular trouble when order of response was restricted to the original order, compared to when it was not restricted; nor were group differences seen when subjects learned new orders of already-familiar positions. Delayed recall of the positions (which had been learned to a common criterion), was not impaired in any group. Results suggested a role of the left-frontal and left-temporal lobes in learning series of manual responses.
mesh_terms: D000293:Adolescent; D000328:Adult; D001931:Brain Mapping; D005260:Female; D005625:Frontal Lobe / Q000601:surgery*; D006801:Humans; D007859:Learning Disabilities / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011183:Postoperative Complications / Q000209:etiology; D011596:Psychomotor Disorders / Q000175:diagnosis / Q000209:etiology*; D013702:Temporal Lobe / Q000601:surgery*