title: [Radiation and chemoradiation therapy of malignant laryngopharyngeal tumors].
abstract: The paper is concerned with the results of open field gamma-beam therapy using grid filters. A group of patients with Stage III-IV tumors received chemoradiotherapy. A single focal radiotherapeutic dose varied from 1.6 to 2.5 Gy, a summary dose from 55 to 70 Gy depending on tumor stage and histological structure. A chemotherapeutic drug was prescribed within the limits of 1/2-2/3 of a standard dose. Intensive substitution and blood-stimulating therapy was provided. With the use of different radiotherapeutic and chemoradiotherapeutic methods the 3- and 5-year survival rates were 19.8% and 14.3%, respectively.
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D008223:Lymphoma / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010610:Pharyngeal Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D011867:Radioisotope Teletherapy / Q000379:methods; D011879:Radiotherapy Dosage
vernacular_title: Luchevaia i khimioluchevaia terapiia zlokachestvennykh opukholeĭ gortanoglotki.