Molecular size of histamine H-1 receptor determined by target size analysis.
Target size analysis (radiation inactivation) was used to study the molecular size of the histamine H-1 receptor of bovine and human cerebral cortex in the intact membrane-bound state. The H-1 receptor in bovine and human cerebral cortex was found to exist in the membrane as a homogeneous population of the same size (160,000 daltons) in each case. Thus no evidence for the existence of multiple forms of the receptor has been found.
D000818:Animals; D002417:Cattle; D002540:Cerebral Cortex / Q000032:analysis*; D006801:Humans; D007700:Kinetics; D008566:Membranes / Q000032:analysis; D008970:Molecular Weight; D011738:Pyrilamine / Q000378:metabolism; D011968:Receptors, Histamine / Q000032:analysis*; D011969:Receptors, Histamine H1 / Q000032:analysis* / Q000528:radiation effects
D011968:Receptors, Histamine; D011969:Receptors, Histamine H1; D011738:Pyrilamine