The pituitary inhibitory system: its role in pain perception.
The present study was designed to investigate the pain relief mechanism of electrical stimulation to the pituitary and the relationship between hypothalamic and pituitary analgesic mechanism through the observation of monkey behavior and characteristics of tooth pulp-evoked potentials. The results suggest that pituitary-stimulating analgesia should be differentiated from hypothalamic-stimulating effect. In view of the facts, the theory of the Pituitary Inhibitory System is proposed.
D000698:Analgesia; D000818:Animals; D001931:Brain Mapping; D005073:Evoked Potentials, Somatosensory; D007033:Hypothalamus, Middle / Q000503:physiopathology; D008253:Macaca mulatta; D010146:Pain / Q000503:physiopathology*; D010902:Pituitary Gland / Q000503:physiopathology*; D013003:Somatosensory Cortex / Q000503:physiopathology; D013787:Thalamic Nuclei / Q000503:physiopathology; D014098:Toothache / Q000503:physiopathology