Liver necrosis after hepatic dearterialization in pigs.
In nine pigs, the livers were dearterialized by a combination of distal occlusion of the hepatic artery with Ivalon (polyvinyl alcohol foam) particles of 150-250 mu and proximal occlusion of the common hepatic artery with Gianturco coils. Necrosis of at least 90% of the liver developed in eight pigs. One pig with less extensive liver necrosis had developed an effective collateral circulation to a large part of the liver. Patency of the portal venous system did not prevent extensive infarction of dearterialized liver tissue.
D000792:Angiography; D000818:Animals; D003097:Collateral Circulation; D006224:Cricetinae; D004621:Embolization, Therapeutic; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D008099:Liver / Q000098:blood supply / Q000473:pathology*; D008102:Liver Circulation; D009336:Necrosis; D013552:Swine