[Effect of phosphemide in combination with dexamethasone on DNA structure in sarcoma 45].
It is shown that under the influence of phosphemide in combination with dexamethasone some characteristics of tumour DNA (content of 5 methyl cytosine, temperature, interval and enthalpy of melting) approximate the corresponding characteristics of DNA of healthy animals' liver better than under the influence of phosphemide only.
D044503:5-Methylcytosine; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001388:Aziridines / Q000494:pharmacology*; D001389:Azirines / Q000494:pharmacology*; D003596:Cytosine / Q000031:analogs & derivatives / Q000378:metabolism; D004273:DNA, Neoplasm / Q000378:metabolism*; D004277:DNA, Single-Stranded / Q000378:metabolism; D003907:Dexamethasone / Q000494:pharmacology*; D004357:Drug Synergism; D008297:Male; D051381:Rats; D012513:Sarcoma, Experimental / Q000378:metabolism*; D014783:Viscosity
D000970:Antineoplastic Agents; D001388:Aziridines; D001389:Azirines; D004273:DNA, Neoplasm; D004277:DNA, Single-Stranded; D044503:5-Methylcytosine; C008880:phosphazine; D003907:Dexamethasone; D003596:Cytosine
Vliianie fosfemida v sochetanii s deksametazonom na strukturu DNK sarkomy 45.