title: [Bolus geometry in various central and peripheral contrast medium applications: study with serial CT using non-ionic contrast media].
abstract: Measurements of concentration in 27 patients with a calibrated Serio-CT yielded for the intravasal contrast medium bolus maximum a value of approx. 23 mg I/ml for the a. carotis with central injection and approx. 14 mg I/ml for the a. iliaca with peripheral injection. 7 invasive measurements were performed at the bifurcation of the aorta, yielding a value of 12.5 mg I/ml with peripheral injection. In all these cases, 40 ml nonionic contrast medium (Iohexol) with an iodine content of 350 mg I/ml were applied. The average bolus half-life was 9.5 sec. measured at the carotid artery, 11.5 sec. at the a. iliaca, and 7 sec. at the bifurcation of the aorta. Differences in bolus geometry were not seen on comparing arterial injection with cava superior injection; likewise, there were no differences between peripheral injections at various speeds. Animal experiments reported in literature show that these observations can be mainly ascribed to vascular dilatation in the minor circulation produced by the contrast medium.
mesh_terms: D002339:Carotid Arteries / Q000000981:diagnostic imaging; D003287:Contrast Media / Q000032:analysis*; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D013679:Technology, Radiologic; D014057:Tomography, X-Ray Computed / Q000295:instrumentation
chemical_list: D003287:Contrast Media
vernacular_title: Bolusgeometrie bei unterschiedlicher zentraler und peripherer Kontrastmittelapplikation: Studie mittels Serio-CT unter Verwendung nichtionischen Kontrastmittels.