[Effect of extreme factors and adaptation to high-altitude conditions on peroxidation indices of serum lipids].
High and low temperatures, physical exercises and acute hypoxia are studied for their effect on indices of peroxide lipid oxidation in highly trained persons under alpine conditions (2100-5600 m). Temperature effects (-15 degrees C and +100 degrees C, for 30 minutes) as well as their combination with acute hypoxy cause an increase (by 10-30%) of malonic dialdehyde and a decrease (by 46-70%) of spontaneous chemoluminescence of blood serum in nonadapted people. Adaptation to alpine conditions in combination with physical exercises and low-caloric diet decreases shifts of these indices, considerably increasing the organism stability to the action of such extreme stress agents as high and low temperatures and acute hypoxy.
D000222:Adaptation, Physiological; D000328:Adult; D000368:Aged; D000531:Altitude; D006801:Humans; D000860:Hypoxia / Q000097:blood*; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013696:Temperature
D008054:Lipid Peroxides
Deĭstvie ékstremal'nykh faktorov i adaptatsii k usloviiam vysokogor'ia na pokazateli perekisnogo okisleniia lipidov v syvorotke krovi.