title: Does general anaesthesia affect the child's auditory middle latency response (MLR)?
abstract: Auditory MLR and ABR were recorded simultaneously in 9 children under general anaesthesia, after electrocochleography had demonstrated a normal hearing threshold. In contrast to the ABR components which in all cases appeared to be clearly recognizable, and with latencies within the normal range, MLR revealed gross abnormalities represented by instability of the components and abnormal latency of the detectable peaks. Since such variations in the MLR pattern may be thought of as a direct consequence of general anaesthesia, it seems likely that these potentials reflect a neural activity which, in children, is affected by CNS drugs.
mesh_terms: D000768:Anesthesia, General; D001299:Audiometry / Q000379:methods*; D001300:Audiometry, Evoked Response / Q000379:methods*; D002675:Child, Preschool; D005072:Evoked Potentials, Auditory / Q000187:drug effects*; D006221:Halothane / Q000494:pharmacology*; D006801:Humans; D007223:Infant
chemical_list: D006221:Halothane