title: [Radiotherapy of carcinoma of the nasopharynx in children after previous chemotherapy. Preliminary results on 21 cases treated at the Institut Gustave-Roussy between 1978 and 1981].
abstract: Between 1978 and 1981, 21 children were treated at IGR for a poorly differentiated carcinoma of the nasopharynx. In hopes of diminishing the radiation doses and the incidence of metastases, the treatment began by either single agent or combination chemotherapy. The total dose of irradiation could be reduced to 50 Gy in 17 patients. The short term results are available for 18 cases. There were 2 isolated local recurrences, 2 isolated nodal recurrences and 1 combined local and nodal recurrence. In march 1983 the overall results revealed the following: of 21 patients initially treated, 10 are alive without local-regional recurrence (but 1 with metastases); 2 are dead metastases; 9 are lost to follow up with metastases.
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D009362:Neoplasm Metastasis; D013997:Time Factors
chemical_list: D000970:Antineoplastic Agents
vernacular_title: La radiothérapie des carcinomes du nasopharynx chez l'enfant après chimiothérapie préalable. Résultats préliminaires sur 21 cas traités à l'Institut Gustave-Roussy entre 1978 et 1981.