[Iron-containing blood proteins in poisoning by polyamide compounds].
Chronic treatment (by means of inhalation) of rats with polyamide substances was accompanied by destabilization of erythrocyte membranes causing penetration of hemoglobin into blood serum. Electrophoresis of blood serum proteins in 7.5% polyacrylamide gel exhibited appearance of additional hemoglobin fractions electrophoretic mobility of which corresponded to the Ist and 4th fractions of erythrocyte hemoglobins. Estimation of hemoglobin composition in blood serum might be used for diagnostics of polyamide intoxication.
D000818:Animals; D001797:Blood Protein Electrophoresis; D004391:Dust / Q000009:adverse effects*; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006454:Hemoglobins / Q000378:metabolism*; D006461:Hemolysis; D007501:Iron / Q000097:blood*; D009757:Nylons / Q000633:toxicity*; D051381:Rats; D013997:Time Factors
D004391:Dust; D006454:Hemoglobins; D009757:Nylons; D007501:Iron
Zhelezosoderzhashchie belki krovi pri intoksikatsii poliamidnymi soedineniiami.