[2 types of neurons differing in their plastic properties: study of ionic mechanisms].
Plasticity ionic mechanisms of 2 types of neurones identified in the brain of snail Helix pomatia: habituating and non-habituating to rhythmic intracellular stimulation by DC pulses were studied. It has been shown that the development of habituation is due to entering of Ca2+ into the cell and by its activation of Ca-dependent K-conductivity of the membrane, leading to hyperpolarization, decrease of input resistance and elimination of spike response to stimulation. Depression of Ca-dependent K-conductivity by quinine totally blocks the ability of the neurons to habituate to stimulation. The data obtained on non-habituating neurons testify that their non-habituation to intracellular stimulation results from their absence or weak manifestation of Ca-dependent K-conductivity in their membrane. Ca2+ entering non-habituating cells during electrical stimulation may have depolarizing and facilitating effects.
D000818:Animals; D002118:Calcium / Q000502:physiology*; D002463:Cell Membrane Permeability; D004558:Electric Stimulation; D005724:Ganglia / Q000166:cytology / Q000502:physiology*; D006185:Habituation, Psychophysiologic / Q000502:physiology*; D006372:Helix, Snails; D066298:In Vitro Techniques; D008564:Membrane Potentials; D009473:Neuronal Plasticity; D011188:Potassium / Q000502:physiology*
D011188:Potassium; D002118:Calcium
Dva tipa neĭronov, razlichaiushchiesia po plasticheskim svoĭstvam: izuchenie ionnykh mekhanizmov.