[Diminished increase in body length in rats as an indicator of toxic injuries].
In four subchronic and three chronic toxicity studies in rats, in which the application of pharmacologically active substances led to a reduction in body weight development, the lengths of the animals were also measured. It could be shown that a lower body weight gain was always accompanied by a reduction in body length increase. With increasing doses or higher toxicity the within-group variations of individual values were smaller and the correlation between body weight and length of the rats was generally greater.
D000375:Aging; D000818:Animals; D001699:Biometry; D001835:Body Weight / Q000187:drug effects; D005260:Female; D008297:Male; D051381:Rats / Q000033:anatomy & histology / Q000254:growth & development*; D014116:Toxicology / Q000379:methods*
Vermindertes Längenwachstum von Ratten als Hinweis auf toxische Schädigungen.