Noninvasive study of high-energy phosphate metabolism in human heart by depth-resolved 31P NMR spectroscopy.
Phosphorus-31 nuclear magnetic resonance (NMR) spectra showing the relative concentrations of high-energy phosphate metabolites have been recorded noninvasively from the human heart in vivo. Spectral data were spatially localized by combining a pulsed magnetic field gradient with surface NMR excitation-detection coils. The location of the selected spectral region was determined by conventional proton NMR imaging immediately before examination by phosphorus-31 NMR spectroscopy.
D000227:Adenine Nucleotides / Q000378:metabolism; D004734:Energy Metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009206:Myocardium / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism*; D010725:Phosphocreatine / Q000378:metabolism
D000227:Adenine Nucleotides; D010710:Phosphates; D010725:Phosphocreatine