Double minutes in the HeLa cell line.
Metaphase preparations of three sublines of the HeLa line showed the presence of double minutes (DM) in varying frequencies. In two sublines (S3 and TCH-3753), the size of the DM was variable, whereas in the Fe-1000 subline, they were uniform. Giemsa banding preparations revealed typical HeLa marker chromosomes in all sublines.
D002460:Cell Line; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D006367:HeLa Cells / Q000166:cytology / Q000648:ultrastructure*; D006801:Humans; D007621:Karyotyping