title: Amiodarone-induced dysthyroidism.
abstract: A 54-year-old man, treated with amiodarone, developed thyrotoxicosis. When rechallenged with the same drug 6 months later, he developed hypothyroidism. The therapeutic implications of this clinical sequence are discussed.
mesh_terms: D000638:Amiodarone / Q000009:adverse effects / Q000627:therapeutic use*; D001572:Benzofurans / Q000627:therapeutic use*; D003327:Coronary Disease / Q000188:drug therapy*; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced*; D007037:Hypothyroidism / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D013961:Thyroid Gland / Q000187:drug effects
chemical_list: D001572:Benzofurans; D000638:Amiodarone