Immunoglobulin E in aqueous humour.
The level of immunoglobulin E (IgE) was determined in the aqueous humour (AH) and serum by particle counting immunoassay (limit of sensitivity: 0.2 IU ml-1). This level in the AH was below 0.75 IU ml-1 in case of senile cataract (n = 22) and ranged from this assumed normal value to 550 IU ml-1 in case of uveitis (n = 37), Fuchs' cyclitis (n = 11), intraocular tumour (n = 7) and perforating ocular injury (n = 6). To know whether the IgE increase was related to a possible local production the AH/serum concentration ratio for IgE was calculated and divided by that for albumin. Values higher than 0.60 were considered as suggestive of a local synthesis and were observed in 31 of the 37 samples examined.
D001082:Aqueous Humor / Q000276:immunology*; D002386:Cataract / Q000276:immunology; D005131:Eye Injuries / Q000276:immunology; D005134:Eye Neoplasms / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis* / Q000096:biosynthesis; D014605:Uveitis / Q000276:immunology; D014606:Uveitis, Anterior / Q000276:immunology
D007073:Immunoglobulin E