Specificity of human milk bile salt-stimulated lipase.
A crude preparation of the bile salt-stimulated lipase in human milk did not differentiate between the primary and secondary esters of several synthetic triacylglycerols. The dioleoyl ester of 2,3-butanediol was also digested, unequivocal confirmation of the absence of positional specificity. Preferential release of 18:2 relative to 16:0 and 18:1 as compared to 18:1t (trans) was observed. The lipase did not differentiate between 16:0 and 18:1 or 16:0 and 18:0.
D001647:Bile Acids and Salts / Q000378:metabolism; D006801:Humans; D006868:Hydrolysis; D008049:Lipase / Q000302:isolation & purification / Q000378:metabolism*; D008895:Milk, Human / Q000201:enzymology*; D013379:Substrate Specificity; D014280:Triglycerides / Q000378:metabolism
D001647:Bile Acids and Salts; D014280:Triglycerides; D008049:Lipase