title: Multiple microcrystal deposition within a family.
abstract: A family is described in which four members in three generations showed evidence of crystal deposition disease: two developed calcium pyrophosphate dihydrate (CPPD) crystal deposition, one calcific periarthritis, and one mixed crystal deposition disease (gout + chondrocalcinosis). This previously undescribed observation supports a possible role for nonspecific heritable connective tissue factors in predisposing to crystal deposition.
mesh_terms: D000328:Adult; D000368:Aged; D002131:Calcium Pyrophosphate; D002805:Chondrocalcinosis / Q000235:genetics; D003460:Crystallization; D005260:Female; D006073:Gout / Q000235:genetics; D006801:Humans; D007592:Joint Diseases / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010489:Periarthritis / Q000235:genetics; D014527:Uric Acid
chemical_list: D014527:Uric Acid; D002131:Calcium Pyrophosphate