Comparative incidence of side effects of a wax-matrix and a sustained-release iron preparation.
The side effects of a wax-matrix iron preparation and a sustained-release iron preparation were compared in a single-blind study of 181 subjects. Evaluations after four and eight weeks of therapy revealed moderate or severe side effects in 52% of the subjects who received the sustained-release preparation but in only 25% of those who received the wax-matrix preparation. Further analysis of the data demonstrated fewer side effects overall among patients who received the wax-matrix preparation. These findings suggest that the wax-matrix preparation is better tolerated than the sustained-release preparation.
D000293:Adolescent; D000328:Adult; D003692:Delayed-Action Preparations; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006801:Humans; D007501:Iron / Q000008:administration & dosage / Q000009:adverse effects*; D014885:Waxes
D003692:Delayed-Action Preparations; D014885:Waxes; D007501:Iron