Depression after treatment with thiazide diuretics for hypertension.
The authors reports eight cases of depression induced by thiazide diuretics prescribed for hypertension and discusses possible mechanisms behind this action. The side effects of thiazide diuretics may be overlooked when they are used with other hypertensives known to cause depression.
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D003866:Depressive Disorder / Q000139:chemically induced*; D004232:Diuretics; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011139:Polythiazide / Q000009:adverse effects; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects*; D014237:Trichlormethiazide / Q000009:adverse effects
D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D011139:Polythiazide; D014237:Trichlormethiazide