title: [Synthesis of N-phenylmaleimides. Kinetics of the antifibrillatory action of a derivative of procainamide].
abstract: The synthesis of some N-phenylmaleimides is described. Among them, reaction of (III a) with procainamide afforded an available prodrug (III c). Antiarrhythmic activity of (III c) was compared with that of procainamide in mice.
mesh_terms: D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis*; D055598:Chemical Phenomena; D002621:Chemistry; D007700:Kinetics; D051379:Mice; D008815:Mice, Inbred Strains; D011342:Procainamide / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D013997:Time Factors
chemical_list: D000889:Anti-Arrhythmia Agents; D011342:Procainamide
vernacular_title: Synthèse des N-phénylmaléimides. Cinétique de l'action antifibrillante d'un dérivé du procainamide.