title: Treatment of infantile subglottic hemangioma. A report of 49 cases.
abstract: Forty-nine laryngeal subglottic hemangiomas were observed in infants over a 9-year period. The diagnosis was always confirmed by direct laryngoscopy. The outcome of 42 of these hemangiomas was studied. A total of 26 infants recovered completely after medical treatment and 16 were intubated; only 4 underwent a tracheostomy. Short-term steroid therapy was sufficient in 7 infants, but long-term administration of corticosteroids was necessary in 14 cases. In 10 of the 16 intubated cases it was possible to withdraw corticosteroids permanently. Of the 6 remaining cases, 32P contact radiation therapy was tried in 2 cases of which one was successful, CO2 laser in 2 cases without success, tracheostomy alone in one case and one child died 2 months after extubation, without dyspnea. This series leads us to recommend corticosteroids as a first therapeutic step and short-term nasotracheal intubation if unsuccessful.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005260:Female; D005931:Glottis; D006391:Hemangioma / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000601:surgery / Q000628:therapy*; D053685:Laser Therapy; D008297:Male; D009365:Neoplasm Regression, Spontaneous
chemical_list: D000305:Adrenal Cortex Hormones