[The enzymatic degradation of DDT. 3. Metabolism of DDT].
DDT orally given to rats is converted into DDD by reductive dechlorination in the liver within 30 min. 6 h after a single application of 10 mg DDT per rat a quantity of 60 mg DDD/kg was indicated in the liver. DDT is stored in the adrenal glands; in the other organs an equilibrium comes up obviously, even with further application. The quantitative ratios are reported. Information on the experimental details of DDT determination and--anticipatory to the following publications--on the analysis of the most relevant metabolites is given.
D000818:Animals; D001673:Biodegradation, Environmental; D001711:Biotransformation; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D003634:DDT / Q000378:metabolism* / Q000652:urine; D003632:Dichlorodiphenyldichloroethane / Q000378:metabolism; D005243:Feces / Q000032:analysis; D007700:Kinetics; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution
D003634:DDT; D003632:Dichlorodiphenyldichloroethane
Zum enzymatischen Abbau des DDT 3. Mitt. Metabolismus des DDT.