Zinc sulphate reduces activity-stress gastric lesions in rats.
Daily i.p. injections of zinc sulphate significantly reduced the frequency and severity of activity-stress gastric lesions in rats in a dose-related fashion. These lesions are believed to be of a non-acid etiology and respond primarily to centrally-acting agents. The present results suggest that some local factors contribute to activity-stress gastric damage.
D000818:Animals; D000897:Anti-Ulcer Agents; D008297:Male; D005082:Physical Exertion; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000209:etiology / Q000517:prevention & control*; D013312:Stress, Physiological / Q000150:complications*; D013431:Sulfates / Q000494:pharmacology*; D015032:Zinc / Q000494:pharmacology*; D019287:Zinc Sulfate
D000897:Anti-Ulcer Agents; D013431:Sulfates; D019287:Zinc Sulfate; D015032:Zinc