title: Methods of randomization in controlled clinical trials.
abstract: In this second article of a series that explores design and analysis issues in controlled clinical trials in emergency medicine, we have discussed the case for randomization, reviewed the methods involved in simple randomization, highlighted some of the practical problems involved with randomization, and presented some modified randomization schemes intended to remedy these problems.
mesh_terms: D002986:Clinical Trials as Topic; D004635:Emergency Medicine; D004992:Ethics, Medical; D006801:Humans; D008722:Methods; D011897:Random Allocation; D012107:Research Design; D012494:Sampling Studies; D013223:Statistics as Topic