Chromium-induced pulmonary cancer. Report of a case and a review of the literature.
A 57-year-old man, whose occupational history was that of a chromate worker for about 35 years, suffered nasal perforation during and died due to pulmonary cancer. In the autopsy materials, the concentration of chromium in the lung tissues was very high, being about 90 times the amount found in normal lungs. The chromium particles in the lung tissues could not be detected by analytical electron microscope, but they could be found in the anthoracotic lesions of the lungs by means of an X-ray microanalyser. The present case was judged to be a case of chromium-induced pulmonary cancer since all the pathologic data obtained were similar to those found in similar cases reported in the literature.
D000230:Adenocarcinoma / Q000032:analysis / Q000139:chemically induced* / Q000473:pathology; D002857:Chromium / Q000032:analysis / Q000633:toxicity*; D004577:Electron Probe Microanalysis; D006801:Humans; D008175:Lung Neoplasms / Q000032:analysis / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced* / Q000473:pathology
D002857:Chromium