The mechanism of fluid and electrolyte transport across corneal endothelium: critical revision and update of a model.
A model for endothelial transport is updated to include recent evidence. We discuss electrolyte movements based on a Na+-K+ ATPase, a Na+-H+ exchanger, a Na+-HCO3 coupler, a Cl- -HCO-3 exchanger, a K+-Cl-coupler, and K+ and anion channels. We discuss near-isotonic transport of fluid on the basis of recent findings of high endothelial osmotic permeability.
D000818:Animals; D001639:Bicarbonates / Q000378:metabolism; D001692:Biological Transport; D001696:Biomechanical Phenomena; D001826:Body Fluids / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism; D003315:Cornea / Q000378:metabolism*; D004573:Electrolytes / Q000378:metabolism*; D004727:Endothelium / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D012964:Sodium / Q000378:metabolism
D001639:Bicarbonates; D002712:Chlorides; D004573:Electrolytes; D012964:Sodium