title: Double minutes in the HeLa cell line.
abstract: Metaphase preparations of three sublines of the HeLa line showed the presence of double minutes (DM) in varying frequencies. In two sublines (S3 and TCH-3753), the size of the DM was variable, whereas in the Fe-1000 subline, they were uniform. Giemsa banding preparations revealed typical HeLa marker chromosomes in all sublines.
mesh_terms: D002460:Cell Line; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D006367:HeLa Cells / Q000166:cytology / Q000648:ultrastructure*; D006801:Humans; D007621:Karyotyping