[Lipids and apoproteins in the blood plasma of children with a hereditary disposition to ischemic heart disease].
An investigation of children with aggravated heredity (coronary disease), and those with vegetovascular dystonia whose parents had no clinically apparent coronary disease demonstrated unidirectional shifts in the lipoprotein system of the two samples as compared to the controls: increased cholesterol levels in low-density lipoproteins and lowered cholesterol in high-density lipoproteins and apoprotein A1. In children with aggravated heredity, these changes are also associated with vegetovascular dystonia, whereas in the absence of the latter they are not apparent or minimal. At the same time, certain differences in cholesterol distribution over lipoprotein fractions and protein/lipid ratios suggest that mechanisms of changes are not identical in children with aggravated heredity and those free from it.
D000293:Adolescent; D001059:Apoproteins / Q000097:blood*; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000235:genetics; D004198:Disease Susceptibility; D006801:Humans; D008055:Lipids / Q000097:blood*; D012306:Risk
D001059:Apoproteins; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D002784:Cholesterol
Lipid i apoproteiny v plazme krovi deteĭ s nasledstvennoĭ predraspolozhennost'iu k ishemicheskoĭ bolezni serdtsa.