[Effectiveness of the radiation therapy of lung cancer with conventional and median dosage fractionation].
A total of 202 patients were studied: 100 patients received radiotherapy of a primary tumor under conditions of mean fractionation and 102 under conditions of common fractionation. In common fractionation a single focal dose was 2 Gy, 5 times a week, a summary dose 50-60 Gy. In mean fractionation a single focal dose was 3 Gy, 3 times a week for 6 week up to a sum of 54 Gy which was equivalent to 60 Gy in common fractionation. In mean fraction 58 patients received radiotherapy only, 42 radiotherapy with adjuvant chemotherapy. In common fractionation the patients' 1,3 and 5-year survival rates for the control group were 52.8, 14.4 and 10.2% respectively. Under conditions of mean fractionation the 3-year survival rate was 14.2%, i. e. similar to that in the control group. In chemoradiotherapy the 3-year survival rate was 12.4% that might be due to the fact that in spite of Stage III these patients' condition was grave. Pulmonary radiation reaction established by x-ray within 4-6 mos. after the termination of therapy with mean fractionation were marked in 63 of 81 patients, whereas in common fractionation in 30 of 90 patients only.
D000230:Adenocarcinoma / Q000401:mortality / Q000532:radiotherapy*; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D005720:Gamma Rays / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011879:Radiotherapy Dosage; D013997:Time Factors
Effektivnost' luchevoĭ terapii raka legkogo pri obychnom i srednem fraktsionirovanii dozy.