Preliminary report on inverse diurnal variation of phenylalanine: implications in maternal phenylketonuria.
Plasma phenylalanine concentrations vary throughout the day by a well-described circadian rhythm. This rhythm is altered in phenylketonuric subjects. The implications for monitoring a pregnant phenylketonuric are considered.
D000328:Adult; D000596:Amino Acids / Q000627:therapeutic use; D002940:Circadian Rhythm; D005260:Female; D005315:Fetal Diseases / Q000517:prevention & control; D006801:Humans; D010649:Phenylalanine / Q000097:blood*; D010661:Phenylketonurias / Q000097:blood* / Q000178:diet therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D014443:Tyrosine / Q000627:therapeutic use
D000596:Amino Acids; D014443:Tyrosine; D010649:Phenylalanine