Oxytocin stimulates lordosis behavior in female rats.
Oxytocin, either intraperitoneally injected (200 ng/rat) or intracerebroventricularly infused (1 ng/rat in 4 microliters saline) 60 and 15 min respectively before testing, significantly increased the lordosis response to the mounting male of ovariectomized, estrogen/progesterone treated rats. The intracerebroventricular infusion of oxytocin 0.1 ng/rat had no effect; nor did saline. These results indicate that oxytocin increases female receptivity, the site of action probably being in the central nervous system.
D000818:Animals; D005260:Female; D007274:Injections, Intraperitoneal; D007276:Injections, Intraventricular; D010121:Oxytocin / Q000008:administration & dosage / Q000494:pharmacology*; D011187:Posture; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013268:Stimulation, Chemical
D010121:Oxytocin