[Effect of diazepam on interference processes].
It has been found in experimental behavioral interference during training in two conditioned reflexes, rapidly following each other, that intraperitoneal injection of diazepam (2 mg/kg) 30 min before training potentiates the inhibitory effect of the defensive reaction to the drinking one. Electrophysiological analysis of the modulating effect of amygdaloid stimulation on the peripheral signal transmission via the central gray matter has demonstrated that in the majority of the neurons, diazepam produced a longer and pronounced inhibition of the excitatory reactions in response to electrocutaneous stimulation after conditioning stimulation of the amygdaloid. The data obtained allow an assumption that inhibitory processes determined by the activity of the GABAergic amygdalofugal system underlie the interference interrelations.
D000679:Amygdala / Q000187:drug effects; D000818:Animals; D001288:Attention / Q000188:drug therapy*; D001921:Brain / Q000187:drug effects; D003072:Cognition Disorders / Q000188:drug therapy*; D003214:Conditioning, Classical / Q000187:drug effects; D003975:Diazepam / Q000494:pharmacology / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D004558:Electric Stimulation; D004924:Escape Reaction / Q000187:drug effects; D007266:Inhibition, Psychological; D008297:Male; D008568:Memory / Q000187:drug effects; D051379:Mice; D008807:Mice, Inbred BALB C; D009474:Neurons / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time / Q000187:drug effects
D003975:Diazepam
Vliianie diazepama na protsessy interferentsii.