A cancer risk assessment for saccharin.
The results from a recently completed large experiment with rats exposed to saccharin show that the dose-response function is much steeper than was previously assumed. Based on this observed steepness, any implied cancer risk at the low doses of interest to man is very small.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D008297:Male; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains; D012306:Risk; D012439:Saccharin / Q000633:toxicity*; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced*
D012439:Saccharin