title: [Effect of food deprivation on the absorption of chick ovalbumin in adult guinea pigs].
abstract: A study was made of the effect of complete alimentary fasting of varying duration on barrier permeability of the gastrointestinal tract for chick ovalbumin (OA). Guinea-pigs which fasted for 96, 48 and 12 (control) hours were fed intragastrically 300 mg chick ovalbumin in saline, and after 3 hours immunoreactive OA was measured in blood serum by competitive radioimmunoassay. It was established that fasting of the animals for 96 h led to a significant increase in unchanged food antigen uptake by systemic circulation. The similar increase of OA intake after 48 h of fasting was insignificant. The data obtained can be explained in terms of a decrease in protease activity and inhibition of amino acid uptake by the intestinal epithelium under complete alimentary fasting.
mesh_terms: D000818:Animals; D000941:Antigens / Q000276:immunology; D002463:Cell Membrane Permeability; D002645:Chickens; D005508:Food Deprivation / Q000502:physiology*; D006168:Guinea Pigs; D007408:Intestinal Absorption; D008297:Male; D010047:Ovalbumin / Q000097:blood* / Q000276:immunology; D011863:Radioimmunoassay; D013997:Time Factors
chemical_list: D000941:Antigens; D010047:Ovalbumin
vernacular_title: Vliianie alimentarnogo golodaniia na vsasyvanie kurinogo oval'bumina u vzroslykh morskikh svinok.