[Effect of lactate on the effectiveness of glucose and succinate oxidation by myocardium homogenates].
Lactate (20 mM) was studied for its effect on the intensity of [1-6-14C] glucose and [1,4-14C] succinate oxidation by the rat myocardial homogenates. It is established that lactate induces specific suppression of aerobic glucose oxidation. A moderate reduction of the succinate and lactate oxidation in their combined incubation is of a non-specific character.
D000818:Animals; D005947:Glucose / Q000378:metabolism*; D006019:Glycolysis / Q000187:drug effects; D066298:In Vitro Techniques; D007773:Lactates / Q000378:metabolism / Q000494:pharmacology*; D009206:Myocardium / Q000378:metabolism*; D010084:Oxidation-Reduction; D051381:Rats; D013386:Succinates / Q000378:metabolism*
D007773:Lactates; D013386:Succinates; D005947:Glucose
Vliianie laktata na éffektivnost' okisleniia gliukozy i suktsinata gomogenatami miokarda.