Effect of intratesticular administration of serum on the physiological status of rat testis.
The effect of loss of integrity of seminiferous tubules on intracellular mechanisms in the testis of rats was studied after intratesticular administration of homologous serum. The increased weights of ventral prostate, seminal vesicles and increased activity of beta glucuronidase in kidney reflected an increased availability of testosterone to the target organs. The pulse labelling of 32P in the nucleic acid fraction of testis was significantly increased. The concentration of testicular DNA was increased while the ascorbic acid was slightly decreased. Activities of the lysosomal enzymes, acid phosphatase and beta glucuronidase increased. The involvement of lysosomal enzymes in the testicular function under altered condition was indicated.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D001205:Ascorbic Acid / Q000032:analysis; D001769:Blood; D004247:DNA / Q000032:analysis; D005966:Glucuronidase / Q000378:metabolism; D007668:Kidney / Q000201:enzymology; D008297:Male; D009929:Organ Size; D011467:Prostate / Q000032:analysis; D051381:Rats; D013737:Testis / Q000502:physiology*
D004247:DNA; D000135:Acid Phosphatase; D005966:Glucuronidase; D001205:Ascorbic Acid