Responsiveness and receptive field size of carp horizontal cells are reduced by prolonged darkness and dopamine.
In the fish retina the interplexiform cells contain dopamine and provide a centrifugal pathway from the inner plexiform layer to horizontal cells of the outer plexiform layer. Dopamine application reduced the responsiveness and receptive field size of cone horizontal cells, as did a prolonged period of complete darkness. Other results suggest that the interplexiform cells may release dopamine after a prolonged period in the dark. The interplexiform-horizontal cell system may modify the strength of the antagonistic surrounds of retinal neurons as a function of time in the dark.
D000818:Animals; D003624:Darkness; D004298:Dopamine / Q000494:pharmacology*; D004594:Electrophysiology; D005071:Evoked Potentials; D005399:Fishes; D008027:Light; D008564:Membrane Potentials; D012160:Retina / Q000166:cytology* / Q000187:drug effects; D013997:Time Factors
D004298:Dopamine