title: [Use of a concentrated and purified vaccine against chlamydial abortion in sheep].
abstract: Attempts were made to immunize sheep against chlamydial abortion with a purified, concentrated, and absorbed vaccine. The latter proved innocuous and unreactive, and was applied at rates of 0.5 to 1.00 cm3. It was found that at a single vaccination of the sheep with 0.5 cm3 as many as 91.42 per cent responded with the production of antichlamydial complement-fixing antibodies on the 45th day of 1:8 to 1:512 titers; 96.43 per cent of the animals responded on the 111th day, the titers ranging from 1:8 to 1:256. At twofold vaccination on the 1st and the 45th day with 0.5 and 1.00 cm3 vaccine, respectively, 100% of the sheep showed antibodies on the 111th day, the titers being within the 1:16 to 1:256 range 49.69 per cent showed antibodies on the 260th day within the 1:4 to 1:512 range. No abortions, stillbirths, and birth of underdeveloped lambs were seen.
mesh_terms: D000034:Abortion, Veterinary / Q000276:immunology / Q000517:prevention & control*; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000302:isolation & purification; D002691:Chlamydophila psittaci / Q000276:immunology*; D004341:Drug Evaluation / Q000662:veterinary; D005260:Female; D007114:Immunization / Q000379:methods / Q000662:veterinary; D011247:Pregnancy; D009956:Psittacosis / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000276:immunology / Q000517:prevention & control*; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines
vernacular_title: Prilozhenie na kontsentrirana i prechistena vaksina sreshtu khlamidiĭniia abort po ovtsete.