title: Prevalence of occupational asthma in silk filatures.
abstract: A clinical survey in two silk filatures revealed that 36.2% of the persons engaged in the processing of natural silk were suffering from bronchial asthma, while 16.9% of the total subjects had asthma of occupational origin. Skin prick tests using crude silkworm cocoon and pupal allergen extracts revealed that 28.8% of the subjects were sensitive to the silkworm-derived allergens. IgE antibodies specific to both cocoon and pupal allergens were demonstrable by RAST in the sera of patients with positive skin reactions and occupational asthma.
mesh_terms: D000918:Antibody Specificity; D001249:Asthma / Q000209:etiology*; D012831:Bombyx; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007194:India; D009784:Occupational Diseases; D012882:Skin Tests; D013783:Textile Industry; D014020:Tissue Extracts
chemical_list: D014020:Tissue Extracts; D007073:Immunoglobulin E