[Function of the hematopoietic system in irradiated animals prophylactically administered 2-amino-2-thiazoline].
The effect of 2-amino-2-thiazoline (2-AT) on radiosensitivity of mice, their haemopoietic system status, and GFUc has been studied. 2-AT was shown to contribute to the survival of an increased number of haemopoietic stem cells, earlier recovery of bone marrow cellularity, and normalization of the spleen weight.
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects; D004353:Drug Evaluation, Preclinical; D005260:Female; D006413:Hematopoietic System / Q000187:drug effects / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011833:Radiation Injuries, Experimental / Q000503:physiopathology / Q000517:prevention & control; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D013154:Spleen / Q000187:drug effects / Q000528:radiation effects; D013844:Thiazoles / Q000627:therapeutic use*
D011837:Radiation-Protective Agents; D013844:Thiazoles; C031363:2-aminothiazoline
Sostoianie krovetvornoĭ sistemy u obluchennykh zhivotnykh pri profilakticheskom vvedenii 2-amino-2-tiazolina.