title: [Esophageal peristalsis and acid clearance. A study method].
abstract: Peristaltic waves account for clearance of acid refluxed into the oesophagus, acting as a second anti-reflux barrier. We have developed a system combining oesophageal motor and pH studies. We use a three-lumen, constantly perfused, manometry probe attached to a pH microelectrode. Primary and secondary oesophageal waves are able to clear injected acid from the oesophagus, whilst non-propulsive tertiary waves do not raise pH back to normal levels. Children with severe GER have a high proportion of tertiary waves, and it is tempting to incriminate these motor disturbances as an important for their bad tolerance to GER.
mesh_terms: D000143:Acids / Q000378:metabolism*; D002648:Child; D004947:Esophagus / Q000032:analysis / Q000502:physiology*; D005764:Gastroesophageal Reflux / Q000503:physiopathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008365:Manometry / Q000295:instrumentation / Q000379:methods; D010528:Peristalsis
chemical_list: D000143:Acids
vernacular_title: Le péristaltisme oesophagien et la "clearance" acide. Une méthode d'étude.