[Distribution of DNA radiation damage throughout the cells and its comparison with cytogenetic injury].
The distribution of DNA lesions induced by irradiation of Chinese hamster fibroblast cells with different doses was determined by the cytochemical method in situ and compared with the number of cytogenetic damages caused by the same doses. The results obtained indicate that not all the DNA lesions but only those occurred in the structurally important chromosome sites initiate chromosome mutagenesis.
D000818:Animals; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D009154:Mutation
D004247:DNA
Izuchenie raspredeleniia radiatsionnykh povrezhdeniĭ DNK po kletkam i ego sopostavlenie s tsitogeneticheskim povrezhdeniem.