title: Registration requirements within the German Federal Health Office.
abstract: Public health authorities responsible for consumer protection in connection with the use of chemical products are faced with several conflicting requirements. In addition to the primary requirements of protecting human health and assessing the balance between benefits and risks, the authorities are faced with the need to identify appropriate tests, to avoid unnecessary testing in experimental animals, to adapt existing test guidelines in the light of new technological and scientific developments and to make optimal use of the facilities and expertise available. Among the measures being taken by the German Federal Health Office to resolve these difficulties, particularly in connection with the testing of chemicals for skin and eye irritancy, are the evaluation of alternatives to animal tests, the encouragement of more effective screening and use of existing test results, promotion of the international exchange of test data, and support for proposed changes in the use of the Draize test.
mesh_terms: D000826:Animal Testing Alternatives; D000818:Animals; D003257:Consumer Product Safety; D003358:Cosmetics / Q000633:toxicity; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005860:Germany, West; D006801:Humans; D007509:Irritants / Q000633:toxicity*; D007880:Legislation, Drug; D010575:Pesticides / Q000633:toxicity; D012042:Registries / Q000592:standards*
chemical_list: D003358:Cosmetics; D007509:Irritants; D010575:Pesticides