In vitro activity of cefbuperazone and other antimicrobial agents against isolates from the female genital tract.
Cefbuperazone (BMY 25182), a new cephamycin, showed activity similar to those of moxalactam and other cephalosporin-cephamycins against aerobic and anaerobic bacteria from female genital tract infections. MICs of the antimicrobial agents were less than or equal to 16 micrograms/ml for greater than 97% of organisms tested. All of the anaerobic bacteria tested were susceptible to clindamycin, metronidazole, and chloramphenicol.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D002513:Cephamycins / Q000494:pharmacology*; D005260:Female; D005836:Genitalia, Female / Q000382:microbiology*; D006801:Humans; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D002513:Cephamycins; C035978:cefbuperazone