title: [Mechanism of impairment of energy metabolism in respiratory muscles in experimental botulism].
abstract: Phase alterations in content of adenylic nucleotides were observed in muscular and nervous tissues in dynamics of botulinic intoxication in rats. Experiments with administration of 4-aminopyridine and alpha-tocopherol showed that a decreased rate of mediator liberation in cholinergic synapses and activation of lipid peroxidation were apparently responsible for impairments in energy metabolism.
mesh_terms: D000227:Adenine Nucleotides / Q000378:metabolism*; D000818:Animals; D001906:Botulism / Q000378:metabolism*; D003964:Diaphragm / Q000378:metabolism*; D004734:Energy Metabolism; D007366:Intercostal Muscles / Q000378:metabolism*; D051381:Rats; D013116:Spinal Cord / Q000378:metabolism; D013997:Time Factors
chemical_list: D000227:Adenine Nucleotides
vernacular_title: K mekhanizmu narusheniia énergeticheskogo obmena v dykhatel'noĭ muskulature pri éksperimental'noĭ botulinicheskoĭ intoksikatsii.