Comparison of the efficacy of furosemide with two furosemide-triamterene combinations in the treatment of cardiac insufficiency.
Nine patients suffering from cardiac insufficiency were given furosemide and two furosemide-triamterene combination products in random order. A statistically significant diuretic response was achieved with all these preparations. The combination of furosemide and triamterene brought about a 'softer' diuresis, no hypokalaemia and the advantage of dosage as only one tablet, thus eliminating the need for taking two separate drugs.
D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D003404:Creatinine / Q000097:blood; D004231:Diuresis; D004338:Drug Combinations; D005260:Female; D005665:Furosemide / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D006331:Heart Diseases / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood; D014223:Triamterene / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D014527:Uric Acid / Q000097:blood
D001786:Blood Glucose; D004338:Drug Combinations; D014527:Uric Acid; D005665:Furosemide; D012964:Sodium; D003404:Creatinine; D011188:Potassium; D014223:Triamterene