[Carotenoid retinopathy. I. Morphologic and functional findings].
Thirty patients who had undergone long-term treatment with carotenoids (max. 14 years and 336 g of carotenoids) were examined. Ophthalmoscopy revealed retinal crystals in 20 patients. The retinal crystals were usually located around the macula, forming a ring, and in one case they were even found in the macula itself. No deterioration of visual acuity or visual field defects were found, but there was a markedly dose-dependent prolongation of the duration of dark adaptation.
D000293:Adolescent; D000328:Adult; D016644:Canthaxanthin; D002338:Carotenoids / Q000009:adverse effects* / Q000031:analogs & derivatives*; D002648:Child; D003460:Crystallization; D003623:Dark Adaptation / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations / Q000009:adverse effects; D004596:Electroretinography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000187:drug effects / Q000473:pathology; D012164:Retinal Diseases / Q000139:chemically induced* / Q000473:pathology; D019207:beta Carotene
D004338:Drug Combinations; D019207:beta Carotene; D002338:Carotenoids; D016644:Canthaxanthin; C041347:phenoro
Carotinoid-Retinopathie. I. Morphologische und funktionelle Befunde.