title: Spontaneous occurrence of Staphylococcus aureus mutants with different pigmentation and ability to produce toxic shock syndrome toxin 1.
abstract: Spontaneous mutants that have pigmentation different than that of their parents were isolated from three Staphylococcus aureus strains associated with toxic shock syndrome. These mutants produced toxic shock syndrome toxin 1 in amounts varying from less than 0.05 to greater than 25 times that produced by the parents. The occurrence of nonpigmented variants may be overlooked if only one isolate from a patient with toxic shock syndrome is selected for analysis.
mesh_terms: D001427:Bacterial Toxins; D004768:Enterotoxins / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D009154:Mutation; D010858:Pigmentation; D012772:Shock, Septic / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000235:genetics* / Q000378:metabolism; D018089:Superantigens
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal