title: Dynamics of the ureterovesical junction; a qualitative analysis of the ureterovesical pressure profile in the pig.
abstract: In pigs, ureterovesical pressure profiles were analyzed by combined prevesical perfusion pressure measurement and microsensor pressure profilometry of the ureterovesical junction, which showed comparable and reproducible fast and slow pressure waves. Cystoscopy revealed that the fast pressure waves were associated with fluid spurts from the ureteral orifice and wrinkling of bladder mucosa over the ureterovesical junction. During slow pressure waves only initial decreases in outflow from the orifice may occur. After dissection of the detrusor muscle at the UVJ only fast pressure waves were recorded. At similar pressure measurements on an inactivated ureter segment which was obliquely passed through the bladder wall only slow pressure waves could be detected. It is concluded that the fast pressure waves of the ureterovesical pressure profile represent peristaltic activity which is generated at the ureterovesical junction and by which fluid may be discharged into the bladder. The slow pressure waves of the pressure profile reflect impairment of flow through the ureterovesical junction by detrusor activity.
mesh_terms: D000818:Animals; D005260:Female; D009092:Mucous Membrane / Q000502:physiology; D009119:Muscle Contraction; D011312:Pressure; D013552:Swine; D014513:Ureter / Q000502:physiology*; D001743:Urinary Bladder / Q000502:physiology* / Q000601:surgery; D014554:Urination; D014563:Urodynamics