title: Senning repair for transposition of the great arteries in the first week of life.
abstract: Infants with D-loop transposition of the great arteries (D-TGA) may have unacceptable results after the balloon septostomy while awaiting surgery. It has been our policy to repair defects in infants with D-TGA and intact ventricular septum or small ventricular septal defect at the time of diagnosis. We report our experience with the Senning operation in 18 newborns less than 1 week of age. The mean age at operation was 3 days (range 12 hr to 7 days) and the mean weight was 3.5 kg (range 2.8 to 4.8). There were two early postoperative deaths (11%) and one late death (5%). Early mortality was associated with preoperative acidosis and congestive heart failure. Late mortality was associated with severe left ventricular outflow tract obstruction (LVOTO). The 15 long-term survivors have been followed for an average of 27 months and 11 of the 16 perioperative survivors have undergone postoperative catheterizations. There was no evidence of systemic or pulmonary venous obstruction. One patient developed LVOTO that led to his death. Two patients had residual atrial shunts. Electrocardiograms revealed no major arrhythmias. All patients are clinically asymptomatic. Good hemodynamic, electrocardiographic, and clinical results can be obtained with correction of D-TGA in the first week of life.
mesh_terms: D001158:Arteries / Q000601:surgery; D006328:Cardiac Catheterization; D004562:Electrocardiography; D006333:Heart Failure / Q000150:complications; D006801:Humans; D000860:Hypoxia / Q000150:complications; D007231:Infant, Newborn; D011183:Postoperative Complications / Q000401:mortality; D013902:Radiography, Thoracic; D014188:Transposition of Great Vessels / Q000601:surgery*