title: [Fiberoptic bronchoscopy in intensive care medicine--functional efficacy and methodological side effects].
abstract: A prospective study was performed to determine the side effects of fiberoptic bronchoscopy on cardiopulmonary function, the influence of bronchial lavage on cardiopulmonary function, and the functional efficacy of fiberoptic bronchoscopy in obstructive atelectasis due to retained secretions. In 17 patients endotracheal intubation was immediately followed by a significant (P less than 0.01) rise in arterial, pulmonary artery and pulmonary capillary wedge pressure, heart rate, and cardiac output. There were no statistically significant differences in arterial blood gases and intrapulmonary right-to-left shunt. Two patients showed circulatory changes indicative of a heart insufficiency on the left side. A significant increase (P less than 0.001) in intrapulmonary right-to-left shunt from 12% to 17.5%, a significant decline in arterial oxygen tension of 15 mm Hg, and a significant increase of cardiac output from 6.4 to 7.71/min following saline solution lavage (20 ml in each bronchus) were observed in nine patients. The results indicate that bronchial lavage is the essential mechanism for the decline in arterial oxygen tension induced by fiberoptic bronchoscopy. In patients with unstable cardiopulmonary status, the cardiovascular response during bronchoscopy may be hazardous and the bronchoscopist should be aware of the pathophysiologic side effects involved. Fifteen therapeutic bronchoscopies were performed in five critically ill patients with obstructive atelectasis, due to retained secretions. Following the procedure, Qs/Qt declined from 23.9% to 15%, cardiac output from 9.3 to 7.31/min, and arterial Po2 increased from 58.9 to 70.9 mm Hg. The differences were statistically significant (P less than 0.0001). The therapeutic value of fiberoptic bronchoscopy in the treatment of obstructive atelectasis is demonstrated by the significant improvement in cardiopulmonary status.
mesh_terms: D001145:Arrhythmias, Cardiac / Q000209:etiology; D001999:Bronchoscopy / Q000009:adverse effects*; D002302:Cardiac Output; D002320:Cardiovascular Physiological Phenomena; D003422:Critical Care; D004322:Drainage; D005336:Fiber Optic Technology; D006339:Heart Rate; D006801:Humans; D007442:Intubation, Intratracheal; D011184:Postoperative Period; D001261:Pulmonary Atelectasis / Q000628:therapy; D011669:Pulmonary Wedge Pressure; D012129:Respiratory Function Tests; D007507:Therapeutic Irrigation
vernacular_title: Die fiberoptische Bronchoskopie in der Intensivmedizin--funktionelle Wirksamkeit und methodische Nebenwirkung.