G-6-PD Jalisco and G-6-PD Morelia: two new Mexican variants.
Two new G-6-PD variants designated G-6-PD Jalisco and G-6-PD Morelia were identified in two unrelated Mexican families. An additional G-6-PD variant was found in each family: G-6-PD Trinacria and G-6-PD A-. In both families compound heterozygotes were identified. G-6-PD Jalisco and G-6-PD Morelia belong to Classes 3 and 4, respectively. G-6-PD Morelia is the first variant from its class with a high Km for NADP and a low Ki for NADPH.
D000328:Adult; D002675:Child, Preschool; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics*; D006801:Humans; D007527:Isoenzymes / Q000235:genetics*; D008297:Male; D008800:Mexico; D010375:Pedigree; D011110:Polymorphism, Genetic
D007527:Isoenzymes; D005954:Glucosephosphate Dehydrogenase