title: Single dose therapy with temocillin in acute gonorrhoea.
abstract: Temocillin has pronounced in vitro activity against both penicillin-sensitive and penicillinase-producing gonococci. A single intramuscular injection of temocillin 0.5 g or 1.0 g resulted in the disappearance of the infecting gonococci in 91% of 75 patients and 94% of 192 patients in 2 separate trials. The systemic and local tolerance of the drug was unusually favourable and no serious side effects were observed.
mesh_terms: D000328:Adult; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D010406:Penicillins / Q000627:therapeutic use*
chemical_list: D010406:Penicillins; C031367:temocillin