[Toxicity of Glucantime. A case].
N-methylglucamine antimoniate (Glucantime) is used to treat visceral leishmaniasis but may give rise to serious and sometimes lethal complications: cardiac, hepatic, renal and haematological disease. These may be prevented by respecting the maximal suggested dosage of 6 cg/kg/day, regular clinical checks of pulse, blood pressure and temperature, biological follow-up of serum creatinin, transaminases and routine electrocardiography.
D000328:Adult; D000965:Antimony / Q000009:adverse effects*; D000981:Antiprotozoal Agents / Q000009:adverse effects*; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000188:drug therapy; D008297:Male; D008536:Meglumine; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000965:Antimony
Toxicité du Glucantime. Une observation.