[Formation of alpha-tocopherol complexes with phosphatidic acid].
High-resolution 1H-nmr spectroscopy and UV spectrophotometry have demonstrated the formation of alpha-tocopherol and phosphatide acid complexes. The complex formation occurs at the expense of two types of interactions: polar interaction of the OH-group of alpha-tocopherol with a keto group of phosphatide acid and hydrophobic interaction of the methyl groups of the chroman nucleus of alpha-tocopherol with cis-unsaturated double bonds of the accyls of phosphatide acid. The role of such complexes in the mechanisms of biomembrane stabilization for preventing the damaging action of phospholipases is discussed.
D004347:Drug Interactions; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D010712:Phosphatidic Acids / Q000032:analysis / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D014810:Vitamin E / Q000032:analysis / Q000378:metabolism*
D010712:Phosphatidic Acids; D014810:Vitamin E
Obrazovanie kompleksov al'fa-tokoferola s fosfatidnoĭ kislotoĭ.