Biodistribution of [14C]PnAO in rats.
The biodistribution of [14C]3,3'-(1,3-propanediyldiimino)-bis(3-methy 1-2-butanone)-dioxime, [( 14C]PnAO) was determined in anesthetized rats. The results of this study show that there is no significant brain accumulation or retention of the uncomplexed ligand in the brain.
D000818:Animals; D001921:Brain / Q000378:metabolism; D002250:Carbon Radioisotopes; D007700:Kinetics; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013667:Technetium / Q000378:metabolism*; D014018:Tissue Distribution
D002250:Carbon Radioisotopes; D015609:Organotechnetium Compounds; D010091:Oximes; C044310:technetium Tc 99m propylene amine oxime; D013667:Technetium