Effect of environmental factors on induced chromosomal aberrations in newborns.
Repeated blood collection was performed in newborns living in 3 distinct areas of the country with different levels of chemical pollution in the environment. Both the classical and SCE techniques were used in parallel. Blood samples from mothers and 1-year-old infants in the same area were also analysed to compare age-dependent sensitivity to mutagens. Cells with classical aberrations increased significantly according to higher chemical pollution, the levels of SCEs were not significantly changed. No age-dependent difference in sensitivity to chemical mutagens was found.
D000328:Adult; D000367:Age Factors; D002648:Child; D002869:Chromosome Aberrations; D003604:Czechoslovakia; D004785:Environmental Pollutants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011247:Pregnancy; D012016:Reference Values; D012854:Sister Chromatid Exchange / Q000187:drug effects
D004785:Environmental Pollutants