title: [The theory of ligand migration in biomacromolecules].
abstract: A model for the process of ligand migration in bio-macromolecules is proposed. We assume that migration occurs by means of fluctuating creation of cavities in bio-macromolecules. A theory of particle migration through the fluctuating gap is created. The rate of migration is determined analytically for limiting cases. Theoretical results are applied to the migration of CO in myoglobin.
mesh_terms: D002248:Carbon Monoxide; D004058:Diffusion; D008024:Ligands; D008954:Models, Biological; D008968:Molecular Conformation; D009211:Myoglobin; D010100:Oxygen
chemical_list: D008024:Ligands; D009211:Myoglobin; D002248:Carbon Monoxide; D010100:Oxygen
vernacular_title: K teorii migratsii ligandov v biomakromolekulakh.