[Radiosensitivity during the irradiation of animals in an altered gaseous environment. A comparative study on mice and rats of the radiation-protective effect of oxygen-deficient gas mixtures].
The radioprotective effect of gas hypoxic mixtures containing 5, 7, 8, 10 and 15% of oxygen on mice and rats was comparatively studied. The dependence of DMF upon oxygen concentration in the mixture was approximated by a hyperbolic function similar to the dependence of the radiomodifying effect of circulatory hypoxia caused by radioprotective agents of the indolylalkylamine series.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004780:Environment, Controlled; D005260:Female; D005720:Gamma Rays; D051379:Mice; D009584:Nitrogen / Q000627:therapeutic use*; D010100:Oxygen / Q000627:therapeutic use*; D011836:Radiation Tolerance; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D051381:Rats; D013045:Species Specificity
D011837:Radiation-Protective Agents; C041364:nitrox; D009584:Nitrogen; D010100:Oxygen
Radiochuvstvitel'nost' pri obluchenii zhivotnykh v izmenennoĭ gazovoĭ srede. Sravnitel'noe issledovanie na myshakh i krysakh protivoluchevogo éffekta kisloroddefitsitnykh gazovykh smeseĭ.