[Comparison of two skin antiseptics in blood transfusion. Comparison with the results of the bacteriologic control of labile blood products].
The comparison of two skin antiseptics (70 degrees alcohol and 0,5% alcoholic chlorhexidine solution) was carried out by the method of in vivo impressions. The study used 45 healthy volonteers from whom a bacteriological sample was taken from both bends of the elbow, without use of an antiseptic, and after the application of one according to usual sample taking methods. The subjects were divided into two sets according to the antiseptic being tested. The results of the cultures after 24 and 48 hours are expressed in the number of germs per cm2, which thus permits us to calculate a reduction in percentage or log 10 form, and to appreciate the efficiency of the antiseptic studied. Routine bacteriological inspection of labile blood products was carried out on products picked at random every week during 18 months of exclusive use of 70 degrees alcohol by the sample taking services. The results show a comparable in vivo effectiveness of the two antiseptics on the superficial aerobic flora of the bend of the elbow, and the ease of use of 70 degrees alcohol has led to its choice. This choice is confronted with the results of the inspection of blood products: out of 1 293 inspections, only one slight contamination (cocci gram+) was found on a unit of whole blood. These data as a whole can be compared with the work of various authors.
D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects; D001793:Blood Preservation; D001803:Blood Transfusion / Q000379:methods*; D002710:Chlorhexidine / Q000627:therapeutic use; D004338:Drug Combinations; D000431:Ethanol / Q000627:therapeutic use; D006801:Humans; D012867:Skin
D000891:Anti-Infective Agents, Local; D004338:Drug Combinations; D000431:Ethanol; D002710:Chlorhexidine
Etude comparée de deux antiseptiques cutanés en transfusion sanguine. Confrontation aux résultats du contrôle bacteriologique des produits sanguins labiles.