Bacteriological effect of cerium-flamazine cream in major burns.
A controlled trial of the use of either 0.05 per cent chlorhexidine for bathing burn wounds or the topical application of a cream containing cerium nitrate and silver sulphadiazine showed that the cerium-flamazine cream significantly reduced the degree of Pseudomonas aeruginosa contamination of the burn wounds of patients with burns covering more than 15 per cent of the body surface area. The adherent eschar produced by treatment with cerium-flamazine provided a satisfactory wound cover until tangential excision could be carried out.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D001424:Bacterial Infections / Q000517:prevention & control; D002056:Burns / Q000188:drug therapy* / Q000382:microbiology; D002563:Cerium / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000627:therapeutic use*; D004338:Drug Combinations / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011549:Pseudomonas / Q000302:isolation & purification; D012837:Silver Sulfadiazine / Q000627:therapeutic use*; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013411:Sulfadiazine / Q000627:therapeutic use*; D013997:Time Factors
D004338:Drug Combinations; C046337:cerous nitrate, sulfadiazine silver drug combination; D013411:Sulfadiazine; C032786:cerium nitrate; D002563:Cerium; D002710:Chlorhexidine; D012837:Silver Sulfadiazine