title: Extraorbital sebaceous carcinoma.
abstract: Although sebaceous carcinoma constitutes 1% to 5.5% of all malignant neoplasms of the eyelid, less than 100 cases arising in extraorbital sites have been reported. We treated two cases of extraorbital sebaceous carcinoma arising in anatomic regions never previously reported, to our knowledge. These tumors occur generally in older patients and affect both sexes equally. No clinical features are characteristic of the tumor, but larger skin lesions should be approached with suspicion. Appropriate histopathologic identification is particularly important in the differential diagnosis. Radical surgery is the only effective treatment for this rare tumor, which can recur locally or produce lymph node and even distant metastases.
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000368:Aged; D001415:Back; D005534:Foot Diseases / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012626:Sebaceous Gland Neoplasms / Q000473:pathology* / Q000601:surgery; D014034:Toes