[Prevention of the stress-induced decrease in natural killer activity by using a beta-adrenergic blocker and vitamin E].
The data are provided on the efficacy of the use of the beta-adrenoblocker inderal and the natural antioxidant vitamin E as agents that prevent the immobilization stress-induced depression of the activity of natural killers. The problems of the prevention of the action of excess catecholamines and activation of lipid peroxidation as pathogenetic component in the development of stressor depression of the activity of natural killers are discussed.
D000818:Animals; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects*; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000276:immunology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011433:Propranolol / Q000627:therapeutic use*; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000276:immunology / Q000517:prevention & control*; D014810:Vitamin E / Q000627:therapeutic use*
D014810:Vitamin E; D011433:Propranolol
Preduprezhdenie stressornogo snizheniia aktivnosti normal'nykh killerov s pomoshch'iu beta-adrenoblokatora i vitamina E.