title: Treatment responses in primary and secondary melancholia: a preliminary report.
abstract: Ten patients suffering from primary affective illness and melancholia were compared to 10 melancholic subjects whose depression was chronologically superimposed on a preexisting nonaffective psychiatric disturbance. Both groups displayed a satisfactory response to treatment with amitriptyline. Similar patterns of improvement were reported in the two groups, and there was a concordance of subjective and objective rating methods.
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications; D000639:Amitriptyline / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000209:etiology / Q000523:psychology; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000150:complications; D010554:Personality Disorders / Q000150:complications; D010555:Personality Inventory; D011569:Psychiatric Status Rating Scales; D019966:Substance-Related Disorders / Q000150:complications
chemical_list: D000639:Amitriptyline