Amygdala norepinephrine involved in two separate long-term memory retrieval processes.
Noradrenergic manipulation of the rodent amygdala results in time-dependent disruption of long-term memory for a one-trial aversive experience. Findings using both state-dependent and consolidation experimental procedures suggest that the norepinephrine system of the amygdala underlies not only consolidation-like mechanisms. There appear to be specific noradrenergic substrates for two or more memory retrieval processes which may be physiologically similar to either acquisition or later memory development involving aversive information.
D000679:Amygdala / Q000502:physiology*; D000818:Animals; D004924:Escape Reaction; D007858:Learning / Q000502:physiology*; D008297:Male; D008568:Memory / Q000502:physiology*; D009638:Norepinephrine / Q000502:physiology*; D051381:Rats
D009638:Norepinephrine