title: Sodium in health and disease: a comparative review with emphasis on herbivores.
abstract: This review aims to illustrate the relationships between a number of basic and clinical aspects of sodium metabolism with special emphasis on herbivores, particularly ruminants. These animals provide a challenge to some traditional views based essentially on humans, dogs and laboratory rats reared on liberal sodium intakes. Detailed attention is focussed on two central issues; the magnitude of sodium requirement and the relative importance of the kidney and the gut in regulating body sodium. Both provide strong reasons to question accepted beliefs.
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002417:Cattle / Q000378:metabolism*; D004285:Dogs; D005110:Extracellular Space / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption; D007668:Kidney / Q000378:metabolism; D009751:Nutritional Requirements; D012756:Sheep / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism / Q000502:physiology*; D014882:Water-Electrolyte Balance
chemical_list: D012964:Sodium