[Rh-incompatibility acidosis in newborn infants following intrauterine transfusion].
Severe foetal Rh erythroblastosis is treated by intrauterine transfusion, in most cases with ACD adenine erythrocyte concentrates. In two cases where delivery took place shortly after the last intrauterine transfusion, metabolic acidosis developed post partum, which could possibly be attributed to the erythrocyte concentrates in the transfusion. Multiple pH level measurements in the ACD adenine erythrocyte concentrates revealed pH levels between 6.4 and 6.8. Erythrocyte concentrates prepared with heparin showed pH levels between 7.18 and 7.25 and should therefore be used for intrauterine transfusion in place of ACD adenine erythrocyte concentrates.
D000138:Acidosis / Q000209:etiology*; D000328:Adult; D001805:Blood Transfusion, Intrauterine / Q000009:adverse effects*; D004899:Erythroblastosis, Fetal / Q000175:diagnosis / Q000628:therapy*; D017707:Erythrocyte Transfusion; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy
Rh-Inkompatibilität-Azidose bei Neugeborenen nach intrauteriner Transfusion.