Celiac disease and spinocerebellar degeneration with normal vitamin E status.
We studied a 47-year-old man with spinocerebellar degeneration and malabsorption due to celiac enteropathy; the serum vitamin E level was normal. The neurologic disorder initially deteriorated despite improvement of small bowel histology on a gluten-free diet and vitamin E therapy, but later stabilized. The etiology of the neurologic disorder in adult celiac disease has not been identified and does not appear to be vitamin E deficiency.
D002446:Celiac Disease / Q000097:blood / Q000150:complications* / Q000178:diet therapy; D002526:Cerebellar Diseases / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D005073:Evoked Potentials, Somatosensory; D006801:Humans; D008297:Male; D008569:Memory Disorders / Q000150:complications; D008875:Middle Aged; D009410:Nerve Degeneration; D009431:Neural Conduction; D013118:Spinal Cord Diseases / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D014810:Vitamin E / Q000097:blood* / Q000627:therapeutic use
D014810:Vitamin E