Optic disk findings in hypervitaminosis A.
Three cases of papilledema secondary to chronic excessive vitamin A intake are presented, and the optic disk changes are documented with intravenous fluorescein angiography. Two of the three patients reported in this study were symptomatic with blurred vision and systemic complaints. The symptoms of blurred vision and systemic complaints disappeared within one week, and papilledema resolved over several months after discontinuance of vitamin A. The fluorescein angiographic changes observed in the optic disk of patients with hypervitaminosis A are similar to those associated with other known causes of papilledema. Since vitamin A is a nonprescription drug, and its indiscriminate use is potentially great, any history of vitamin ingestion should be elicited during the evaluation of papilledema.
D000328:Adult; D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D009898:Optic Disk / Q000187:drug effects*; D010211:Papilledema / Q000139:chemically induced*; D014792:Visual Acuity / Q000187:drug effects; D014801:Vitamin A / Q000009:adverse effects* / Q000097:blood
D014801:Vitamin A