Serial ECG measurements at controlled plasma levels of nortriptyline in depressed children.
The authors investigated ECG measurements in 21 children with major depressive disorder treated with nortriptyline at plasma levels of 50-100 ng/ml. P-R and QRS intervals and heart rate measured at baseline and once a week during treatment remained within guidelines.
D000367:Age Factors; D001835:Body Weight; D002648:Child; D002675:Child, Preschool; D003866:Depressive Disorder / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D009661:Nortriptyline / Q000097:blood* / Q000627:therapeutic use
D009661:Nortriptyline