title: Effects of deficient and adequate dietary magnesium concentrations on body magnesium concentrations in wethers.
abstract: Effects of 2 dietary Mg concentrations (deficient and adequate: 0.04 and 0.12 g of Mg/100 g of dry matter, respectively) on body fluid and tissue Mg concentrations and performance of wether lambs were evaluated in a 28-day trial. Nine blood and 6 urine samples were collected from each wether. After 28 days, CSF and wool samples were collected, and diet, body fluids, and tissues were analyzed for mineral concentration. Diet effects on serum and urine Mg concentrations were noticed after day 3 (P less than 0.01; P less than 0.05, respectively). Mean serum and urine Mg concentrations for 6 sampling periods were correlated (r = 0.83, P less than 0.001; No. of samples = 12). The effect of dietary Mg on CSF Mg concentrations approached significance (P less than 0.10). Effects of diet on cardiac muscle, liver, and 3rd metatarsal bone Mg contents or hematologic criteria were not observed. Diet affected wool and kidney cortex Mg contents (P less than 0.02). Individual mean 28-day serum Mg concentration was correlated with wool Mg content (r = 0.73, P less than 0.05; n = 8) and with kidney cortex Mg content (r = 0.75, P less than 0.05; n = 8). Wethers fed low Mg diet excreted less urine Ca (P less than 0.001) and had slightly lower serum Ca and K values (P less than 0.10) than did wethers fed high Mg. Significant differences in cardiac muscle, liver, spleen, or kidney cortex Ca contents were not observed. Wethers fed low Mg diet consumed less dry matter and gained less weight (P less than 0.001) than did wethers fed high Mg diet. Body fluid and tissue macromineral concentrations of 1 wether with hypomagnesemic tetany are presented for prognostic and diagnostic purposes.
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D005527:Food, Fortified; D007672:Kidney Cortex / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008274:Magnesium / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008277:Magnesium Oxide / Q000008:administration & dosage*; D008297:Male; D009206:Myocardium / Q000378:metabolism; D009751:Nutritional Requirements; D012756:Sheep / Q000378:metabolism*; D014935:Wool / Q000378:metabolism
chemical_list: D008277:Magnesium Oxide; D008274:Magnesium