[Mycetoma caused by Petriellidium boydii: treatment with ketoconazole].
A case of mycetoma of the lower leg (Madura foot) with bone involvement caused by Petriellidium boydii is presented. After an initially favourable therapeutic response to ketoconazole (2 X 200 mg/die) the process recurred despite proven sensitivity of the fungus in vitro. It could not be controlled with conservative treatment and ultimately necessitated amputation of the lower leg. A striking, hitherto unreported feature of mycetoma was the episodic occurrence of circulating immune complexes with febrile monoarthritis of the adjacent ankle.
D000328:Adult; D000671:Amputation, Surgical; D005533:Foot Dermatoses / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use*; D008297:Male; D008271:Mycetoma / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D011541:Pseudallescheria / Q000302:isolation & purification; D012008:Recurrence; D012867:Skin / Q000473:pathology
D007654:Ketoconazole
Myzetom durch Petriellidium boydii: Behandlung mit Ketoconazol.