[Statistical aspects of the relation of the radioprotective action of mercaptoethylamine derivatives and analogs to their electron parameters].
Numerous S-containing substances were used to study the radioprotective efficiency of the preparations depending on their microscopic characteristics. The method of statistical comparison of the qualitative parameters was used to show that the energy parameters were the most informative electron characteristics of the molecules. Each of these parameters correlated with the physicochemical processes induced in a biological system by ionizing radiation. Quantitative estimates were made associating the protective efficiency of the substances under study with variations in the electron parameters.
D004583:Electrons; D008624:Mercaptoethylamines / Q000494:pharmacology*; D008968:Molecular Conformation; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D013223:Statistics as Topic; D013329:Structure-Activity Relationship
D008624:Mercaptoethylamines; D011837:Radiation-Protective Agents
Statisticheskie aspekty sviazi radiozashchitnogo deĭstviia proizvodnykh merkaptoétilamina i ego analogov s ikh élektronnymi parametrami.