Applied potential tomography: possible clinical applications.
Applied potential tomography (APT) or electrical impedance imaging has received considerable attention during the past few years and some in vivo images have been produced. This paper reviews the current situation in terms of what in vivo results have been and are likely to be obtained in the near future. Both static and dynamic imaging are possible and these two areas are dealt with separately. Features of the existing in vivo imaging system are good tissue contrast, high-speed data collection, good sensitivity to resistivity changes, low spatial resolution, low cost and no known hazard. It is concluded that the most promising way forward to clinical application in the short term is to use dynamic as opposed to static imaging. An example of lung imaging is shown and the application to measuring regional ventilation and pulmonary oedema is discussed. Use of APT for the detection of intraventricular bleeding in neonates is discussed as is the proven ability to study gastric physiology by imaging resistivity distribution changes following the ingestion of conducting or insulating fluids. Other areas of possible application which are considered are blood flow measurement, cell counting, measurement of lean-fat ratios and the detection of soft tissue lesions.
D002452:Cell Count / Q000295:instrumentation; D002543:Cerebral Hemorrhage / Q000175:diagnosis; D003560:Cysts / Q000175:diagnosis; D004553:Electric Conductivity; D005746:Gastric Emptying; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000502:physiology; D010992:Plethysmography, Impedance; D011654:Pulmonary Edema / Q000175:diagnosis; D012983:Soft Tissue Neoplasms / Q000175:diagnosis; D014054:Tomography / Q000379:methods*