[Genetic nature of atrophic rhinitis in swine. II. Cytogenetic research].
This work is concerned with the problem of the nature of the atrophic rhinitis in swine. Our study demonstrates that the filter-passers when injecting intranasal provoke catarrhal rhinitis in sucking-pigs and rabbits and the disease lasts 10-12 days. Guinea-pigs and white mice show no disease symptoms after injection. After four passages of filter-passers through sucking-pigs, the pathogenic properties do not restore. The sucking-pigs and laboratory animals show no changes in organs and in nasal cavity. The findings of cytogenetic and allergic investigations indicate genetic aspects of this disease. To eliminate atrophic rhinitis, it is necessary to reveal heterozygotes, carry out experimental matings and analysis of hybrids. To date, a recessive gene is considered to mediate the disease. To obtain healthy offspring, animals heterozygous for this gene should be bred.
D000782:Aneuploidy; D000818:Animals; D001854:Bone Marrow Cells; D002869:Chromosome Aberrations; D004171:Diploidy; D005260:Female; D007621:Karyotyping; D008297:Male; D012222:Rhinitis, Atrophic / Q000235:genetics / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000235:genetics*
Geneticheskaia priroda atroficheskogo rinita. Soobshchenie II. Tsitogeneticheskoe issledovanie.