Nucleolar changes in goldfish retinal ganglion cells in response to an optic nerve lesion are not perturbed by a second lesion.
The reaction of the goldfish retinal ganglion cells to optic nerve crush, as indicated by an increase in nucleolar incidence 4 to 5 days after this lesion, was not significantly affected if a second nerve crush was made within 3 days after the first. This appears to rule out axon sprouting as the initiating event for the cell body reaction to axotomy.
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D002466:Cell Nucleolus / Q000648:ultrastructure*; D006054:Goldfish; D009409:Nerve Crush; D020221:Optic Nerve Injuries; D012160:Retina / Q000648:ultrastructure*; D012165:Retinal Ganglion Cells / Q000648:ultrastructure*