title: Migration-induced changes in blood pressure: a controlled longitudinal study.
abstract: A longitudinal study of the effects of migration on blood pressure and related factors is being carried out in members of a black Kenyan population who migrate from a traditional rural community to an urban environment. Data on the first 139 migrants (78 male, 61 female) and 204 control non-migrants (126 male, 78 female) who have been followed up for a period of 6 months are presented. Blood pressure changes rapidly on migration (within the first 2 months); thereafter trends between migrants and controls differ. Significant differences in systolic pressure between migrants and controls are found at all examinations during the 6 month follow-up in both sexes. Diastolic pressure falls in controls but rises in migrants, the greatest difference being seen at the 6 month examination. Migration is associated with a marked increase in dietary sodium and a fall in potassium demonstrated by measurements of urinary electrolyte excretion in 3 X 12 h or 3 X 24 h urine collections. Analysis of covariance shows that the blood pressure differences between migrants and controls are partly explained by urinary sodium/potassium ratios and in some instances by body weight.
mesh_terms: D001794:Blood Pressure; D001835:Body Weight; D004032:Diet; D005260:Female; D006801:Humans; D007630:Kenya; D008137:Longitudinal Studies; D008297:Male; D011188:Potassium / Q000652:urine; D012964:Sodium / Q000652:urine; D014171:Transients and Migrants
chemical_list: D012964:Sodium; D011188:Potassium