[Various parameters of hemostasis in patients with chronic liver diseases].
The aim of the study was to investigate the nature and the possible correlations between abnormalities of platelet function and haemostatic and fibrinolytic activity in a group of 33 patients with biopsy-proven chronic liver disease. A slight decrease in prothrombin activity, AT III and plasminogen levels was noticed in the patients studied. Significantly enhanced levels of intraplatelet 5HT was also found in patients with cirrhosis and in those with chronic active hepatitis. Changes in these parameters were generally independent from each other, the only correlation being found between prothrombin activity and AT III levels in patients with cirrhosis.
D000328:Adult; D000368:Aged; D000990:Antithrombin III / Q000032:analysis; D001792:Blood Platelets / Q000032:analysis; D005234:Fatty Liver / Q000503:physiopathology; D005260:Female; D006487:Hemostasis; D006521:Hepatitis, Chronic / Q000503:physiopathology; D006801:Humans; D008103:Liver Cirrhosis / Q000503:physiopathology; D008107:Liver Diseases / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010958:Plasminogen / Q000032:analysis; D010976:Platelet Count; D011517:Prothrombin Time; D012701:Serotonin / Q000097:blood
D012701:Serotonin; D000990:Antithrombin III; D010958:Plasminogen
Studio di alcuni parametri dell'emostasi in pazienti con malattie croniche epatiche.