Non-allergic bronchial hyperreactivity in asthmatic children decreases with age and increases with mite immunotherapy.
Bronchial reactivity to histamine increased 2-fold or greater in six of seven mite-sensitive asthmatic children after mite immunotherapy for 1 year. Bronchial reactivity decreased 2-fold or greater in seven of the eight subjects who received no injections (P = .008).
D000375:Aging; D001249:Asthma / Q000276:immunology* / Q000503:physiopathology; D001980:Bronchi / Q000276:immunology*; D001985:Bronchial Provocation Tests; D002648:Child; D005260:Female; D006801:Humans; D007167:Immunotherapy; D008297:Male; D008925:Mites / Q000276:immunology*; D012129:Respiratory Function Tests; D012882:Skin Tests