Acute thrombotic complications of myeloproliferative disorders in young adults.
Two young adults with myeloproliferative disease had recurrent thrombotic episodes, which were life threatening or associated with a risk of serious disability. Both patients were treated for arterial occlusive disease, and treatment in one instance reversed spastic paraplegia. During a subsequent two-year period of observation, they have remained symptom free. During that time they have been treated with aspirin, and platelet counts have been maintained at one million/mm3 or less.
D000208:Acute Disease; D000328:Adult; D006801:Humans; D008297:Male; D008638:Mesenteric Arteries; D009128:Muscle Spasticity / Q000209:etiology; D010264:Paraplegia / Q000209:etiology; D011087:Polycythemia Vera / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D013162:Splenic Vein; D013922:Thrombocytosis / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D013927:Thrombosis / Q000097:blood / Q000188:drug therapy / Q000209:etiology*