[Chromatin breakdown in the white blood cells of rats during irradiation and in combined radiation injury under cystamine protection].
The polydeoxyribonucleotide (PDN) level in leukocytes of peripheral blood of rats treated with cystamine adequately reflects the severity and outcome of radiation sickness. Preventive application of cystamine against the combined effect of ionizing radiation and heat decreased the PDN level in white blood cells but did not influence the survival of animals.
D000818:Animals; D002056:Burns / Q000097:blood* / Q000517:prevention & control; D002843:Chromatin / Q000528:radiation effects*; D003538:Cystamine / Q000627:therapeutic use*; D005720:Gamma Rays; D007962:Leukocytes / Q000528:radiation effects*; D008297:Male; D011089:Polydeoxyribonucleotides / Q000097:blood / Q000528:radiation effects; D011833:Radiation Injuries, Experimental / Q000097:blood* / Q000517:prevention & control; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D002843:Chromatin; D011089:Polydeoxyribonucleotides; D003538:Cystamine
Raspad khromatina kletok beloĭ krovi krys pri obluchenii i kombinirovannom radiatsionnom porazhenii v usloviiakh zashchity tsistaminom.