Haptoglobin groups and rheumatoid arthritis.
Haptoglobin types were determined in 200 patients with rheumatoid arthritis (RA) subdivided according to sex and familial occurrence of polyarthritis. A highly significant excess of the Hp2 gene was found among patients with a family history of polyarthritis, more pronounced among males. The possible association between Hp2 and predisposition for increased immune reactivity is discussed.
D001172:Arthritis, Rheumatoid / Q000235:genetics*; D005260:Female; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D008297:Male; D012737:Sex Factors
D006242:Haptoglobins