title: Changes in urea nitrogen and creatinine concentrations in the vitreous humor of cattle after death.
abstract: The mean urea nitrogen concentration in vitreous humor (VUN) in 97 healthy steers after death was 15.7 mg/dl. The mean serum urea nitrogen concentration in the same cattle was 20.0 mg/dl. The mean vitreous creatinine (VC) concentration was 0.7 mg/dl, and the serum creatinine value was 1.5 mg/dl. The VUN and VC were both significantly lower than serum urea nitrogen and serum creatinine, respectively, but varied in a consistent, predictable manner. In tests with 10 cows, postmortem intervals as long as 36 hours and ambient temperatures up to 30 C had no significant effects on VUN and VC. Evaluation of 8 animals with uremia confirmed that the vitreous humor is a stable fluid compartment after death, usable as an indicator of serum urea nitrogen and creatinine.
mesh_terms: D000003:Abattoirs; D000818:Animals; D001806:Blood Urea Nitrogen / Q000662:veterinary; D002417:Cattle / Q000378:metabolism*; D002418:Cattle Diseases / Q000378:metabolism; D003404:Creatinine / Q000097:blood / Q000378:metabolism*; D007674:Kidney Diseases / Q000378:metabolism / Q000662:veterinary; D008297:Male; D009584:Nitrogen / Q000378:metabolism*; D013696:Temperature; D014508:Urea / Q000378:metabolism*; D014822:Vitreous Body / Q000378:metabolism*
chemical_list: D014508:Urea; D003404:Creatinine; D009584:Nitrogen