[Changes in the immunological indices after splenectomy and the reimplantation of splenic fragments in an experiment].
Splenectomized guinea-pigs underwent autotransplantation of splenic fragments into the greater omentum or mesentery of small intestine. Twenty-five to thirty days after operation the animals were infected with S. aureus and then were examined over time before and after infection at different times. Measurements were taken of T lymphocytes, B lymphocytes, lymphocytes with staphylococcal receptors, as well as of the content of neutrophils with IgG Fc-fragment and complement receptors. It was established that in guinea-pigs subjected to splenectomy followed by autotransplantation of decapsulated splenic fragments, the experimental generalized staphylococcal infection took a milder course, which was manifested by an increase in the above immunologic characteristics as compared to animals undergoing splenectomy alone.
D000818:Animals; D006168:Guinea Pigs; D007111:Immunity, Cellular; D010180:Pancreatectomy; D011184:Postoperative Period; D011951:Receptors, Complement / Q000032:analysis; D011961:Receptors, Fc / Q000032:analysis; D013154:Spleen / Q000276:immunology* / Q000637:transplantation; D013156:Splenectomy; D013203:Staphylococcal Infections / Q000276:immunology; D014181:Transplantation Immunology; D014182:Transplantation, Autologous
D011951:Receptors, Complement; D011961:Receptors, Fc
Izmenenie immunologicheskikh pokazateleĭ posle splenéktomii i reimplantatsii fragmentov selezenki v éksperimente.