title: Testosterone and dihydrotestosterone levels in epididymis, vas deferens, seminal vesicle and preputial gland of mice after hCG injection.
abstract: Temporal changes of testosterone (T) and dihydrotestosterone (DHT) levels were measured by RIA in epididymis, vas deferens, seminal vesicle and preputial gland of adult male mice after a single injection of hCG. The response of circulating T to hCG stimulation was rapid and persisted over a period of 48 h. The temporal changes of androgen content of target organs paralleled the modifications of circulating T. In all organs the high androgen levels attained at 1 or 4 h plateaued until 24 h, decreased thereafter and returned to basal values at 72 h. The concentration of T by sex accessory organs was more accelerated by hCG injection than its conversion into DHT.
mesh_terms: D000818:Animals; D006063:Chorionic Gonadotropin / Q000494:pharmacology*; D013196:Dihydrotestosterone / Q000378:metabolism*; D004822:Epididymis / Q000378:metabolism*; D005837:Genitalia, Male / Q000187:drug effects; D007700:Kinetics; D008297:Male; D010413:Penis / Q000378:metabolism*; D051381:Rats; D012627:Sebaceous Glands / Q000378:metabolism*; D012669:Seminal Vesicles / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism*; D013997:Time Factors; D014649:Vas Deferens / Q000378:metabolism*
chemical_list: D006063:Chorionic Gonadotropin; D013196:Dihydrotestosterone; D013739:Testosterone