title: Differences in metabolic potential of skeletal muscle fibres and their significance for metabolic control.
abstract: The role of an increase in oxidative potential of skeletal muscle in the enhanced work capacity and greater use of fat as a fuel after endurance training is discussed. Evidence is presented to illustrate that this adaptive response is probably expressed at the cellular level by a more rapid translocation into the mitochondria of the ADP generated during contractile activity. The consequence of this is a tighter control over the glycolytic process thereby creating more favourable conditions for the entry of acetyl units derived from beta-oxidation of fatty acids into the citric acid cycle.
mesh_terms: D000818:Animals; D009119:Muscle Contraction; D009132:Muscles / Q000201:enzymology / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D005082:Physical Exertion; D051381:Rats