Effect of cocaine dependence on plasma phenylalanine and tyrosine levels and on urinary MHPG excretion.
Eight cocaine-dependent subjects had significantly lower urinary 3-methoxy-4-hydroxyphenylglycol excretion than did eight normal control subjects. Cocaine-dependent subjects also had lower plasma tyrosine levels but not to a statistically significant degree.
D000328:Adult; D003042:Cocaine / Q000494:pharmacology; D005260:Female; D006018:Glycols / Q000652:urine*; D006801:Humans; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000652:urine*; D008875:Middle Aged; D009638:Norepinephrine / Q000378:metabolism; D010649:Phenylalanine / Q000097:blood*; D019966:Substance-Related Disorders / Q000097:blood / Q000378:metabolism* / Q000652:urine; D014443:Tyrosine / Q000097:blood*
D006018:Glycols; D014443:Tyrosine; D010649:Phenylalanine; D008734:Methoxyhydroxyphenylglycol; D003042:Cocaine; D009638:Norepinephrine