[Depolarization of primary afferents evoked by cyclically modulated natural activity of proprioceptors of the hindlimb of the cat].
The primary afferent depolarization (PAD) evoked during passive sinusoidal movements of a hindlimb in the ankle joint was investigated in decerebrated cats. The frequency of movements varied within 0.14-5.0 Hz, the amplitude of the joint angle with respect to the axis of the tibia changed from 90 degrees to 130 degrees. The dorsal root potential (DRP) negativity increased both during flexion and during extension of the joint. The amplitude of the evoked DRPs was about 50-100 mV. A strong negative correlation was observed between the latency and rise time of the DRP and the frequency of the joint angle changes. During flexion the latency changed from 650 ms at 0.14-0.16 Hz frequency to 100-110 ms at 2.0 Hz and higher frequencies; during extension at the same frequencies the latency changed from 300 ms to 80-85 ms. The latency and rise time became minimal at 2.0 Hz frequency and practically did not change during the further increase of the oscillation frequency. The cord dorsum potential (CDP) evoked by the cutaneous nerve stimulation was recorded in parallel with the DRP. Periodical changes of the N-component of the CDP were in the opposite phase to changes of the DRP. Mechanisms of the observed changes of the PAD and functional significance of these changes during rhythmical motor acts are discussed.
D000818:Animals; D000843:Ankle Joint / Q000294:innervation; D002415:Cats; D003655:Decerebrate State / Q000503:physiopathology; D005071:Evoked Potentials; D006614:Hindlimb / Q000294:innervation*; D009475:Neurons, Afferent / Q000502:physiology; D010525:Peripheral Nerves / Q000502:physiology*; D011434:Proprioception; D011930:Reaction Time / Q000502:physiology; D012867:Skin / Q000294:innervation
Depoliarizatsiia pervichnykh afferentov, vyzvannaia tsiklicheski modulirovannoĭ estestvennoĭ aktivnost'iu propriotseptorov zadneĭ konechnosti.