Cochlear vessel permeability to horseradish peroxidase in the normal and acoustically traumatized chinchilla: a reevaluation.
A method involving incubation of intact cochleae using the small protein, horseradish peroxidase, has revealed that a barrier exists between the blood and the stria vascularis. This barrier is more tenuous than the barrier that exists across other cochlear vessels. The stria-strial vessel barrier can be altered physiologically by acoustic trauma or artifactually by dissection.
D000818:Animals; D002199:Capillary Permeability; D002682:Chinchilla / Q000502:physiology*; D003051:Cochlea / Q000098:blood supply / Q000502:physiology*; D006317:Hearing Loss, Noise-Induced / Q000503:physiopathology*; D006735:Horseradish Peroxidase / Q000378:metabolism; D013316:Stria Vascularis / Q000502:physiology
D006735:Horseradish Peroxidase