Formation of autophagosomes in the pinealocytes of the rat and mongolian gerbil (Meriones unguiculatus): a lysosome wrapping mechanism?
Autophagosome formation in rat and gerbil pinealocytes is described. It starts with the setting up of a tubular acid phosphatase-rich cisterna which gradually wraps around cytoplasmic areas to be catabolized. In light of obtained findings, it seems that the autophagosome formation in pinealocytes is a type of lysosome wrapping mechanism.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D005849:Gerbillinae; D006651:Histocytochemistry; D008247:Lysosomes / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D010587:Phagocytosis; D010870:Pineal Gland / Q000166:cytology* / Q000201:enzymology / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains
D000135:Acid Phosphatase