Insulin dependent diabetes and goitre in a case of hypomelanosis of Ito (Incontinentia Pigmenti Achromians).
Incontinentia Pigmenti Achromians (IPA) or, more aptly, Hypomelanosis of Ito is now largely accepted as a Neurocutaneous Disorder. Studies, so far, have focussed on the ultrastructural abnormalities and to our knowledge, there have been no attempts to ascertain if there is a particular HLA pattern. We describe an interesting case where IPA occurred in association with Insulin Dependent Diabetes as well as a goitre, suggesting that HLA studies may well be worthwhile. The literature is also reviewed.
D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000235:genetics; D005260:Female; D006042:Goiter / Q000150:complications* / Q000235:genetics; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008297:Male; D009508:Nevus, Pigmented / Q000150:complications* / Q000235:genetics; D012878:Skin Neoplasms / Q000150:complications* / Q000235:genetics
D006680:HLA Antigens