Comparison of two preliminary methods of quantitative linkage analysis.
Two methods of quantitative linkage analysis were evaluated as screening tests for the presence of major genes that influence the expression of a quantitative trait. Our analyses of computer-simulated pedigree data indicate that both methods can be very informative in providing evidence for major genes.
D003201:Computers; D005786:Gene Expression Regulation; D005787:Gene Frequency; D008040:Genetic Linkage; D005838:Genotype; D010641:Phenotype; D011995:Recombination, Genetic