The effects of vitamin A nutritional status on glutathione levels and microsomal lipid peroxidation in rat lung.
In vitamin A-deficient rats, the glutathione level in lung was diminished and microsomal lipid peroxidation much increased. In vitamin A-loaded animals, however, both were depressed below control. Thus vitamin A protection against lipid peroxidation is independent of glutathione.
D000818:Animals; D005978:Glutathione / Q000378:metabolism*; D008054:Lipid Peroxides / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D008861:Microsomes / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014801:Vitamin A / Q000502:physiology*; D014802:Vitamin A Deficiency / Q000378:metabolism
D008054:Lipid Peroxides; D014801:Vitamin A; D005978:Glutathione