title: Comparison of two preliminary methods of quantitative linkage analysis.
abstract: Two methods of quantitative linkage analysis were evaluated as screening tests for the presence of major genes that influence the expression of a quantitative trait. Our analyses of computer-simulated pedigree data indicate that both methods can be very informative in providing evidence for major genes.
mesh_terms: D003201:Computers; D005786:Gene Expression Regulation; D005787:Gene Frequency; D008040:Genetic Linkage; D005838:Genotype; D010641:Phenotype; D011995:Recombination, Genetic