[Successful therapy of recurrent hypoglycemias by surgical removal of a malignant hemangiopericytoma].
Tumor growth in a 72-year-old male patient with malignant haemangiopericytoma in the left hemithorax could be followed radiologically for 4 years before symptoms of recurrent hypoglycaemia appeared. The endogenous insulin level in serum was maximally and serum IGF-1 and IGF-2 markedly reduced. An intravenous arginine load test showed a normal stimulation capacity of the pancreatic glucagon secretion but not that of insulin. After resection of the tumor, blood sugar metabolism was completely normalised. The insulin level, IGF-1 and IGF-2 in serum returned to normal.
D000368:Aged; D001120:Arginine; D002096:C-Peptide / Q000032:analysis; D006442:Glycated Hemoglobin / Q000032:analysis; D006393:Hemangiopericytoma / Q000601:surgery*; D006801:Humans; D007003:Hypoglycemia / Q000628:therapy*; D008297:Male; D013902:Radiography, Thoracic; D013899:Thoracic Neoplasms / Q000601:surgery*
D001120:Arginine; D002096:C-Peptide; D006442:Glycated Hemoglobin
Erfolgreiche Therapie rezidivierender Hypoglykämien durch operative Entfernung eines malignen Hämangioperizytoms.