[Quinolylhydrazones with potential antimicrobial and antiparasitic activity].
Quinolinehydrazones prepared by condensation of hydrazinoquinolines with 1-phenyl-2,5-dimethyl-3-pyrrolcarboxaldehyde, 2-chloro-4-dimethylaminobenzaldehyde and 2,6-dichlorobenzaldehyde are described. All compounds were tested in vitro for antimicrobial activity, the results obtained are shown and discussed. The quinolinehydrazones of the 1-phenyl-2,5-dimethyl-3-pyrrolcarboxaldehyde were tested in vivo against Hymenolepis nana and Taenia taeniaeformis and proved inactive.
D000634:Aminoquinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D000935:Antifungal Agents / Q000138:chemical synthesis; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D006835:Hydrazones / Q000138:chemical synthesis / Q000494:pharmacology; D006926:Hymenolepis / Q000187:drug effects; D010271:Parasites / Q000187:drug effects*; D013621:Taenia / Q000187:drug effects
D000634:Aminoquinolines; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D006835:Hydrazones
Chinolilidrazoni a potenziale attività antimicrobica ed antiparassitaria.