Sustained cerebral vasoconstriction during bilateral sympathetic stimulation in anesthetized rabbits.
Temporal aspects of bilateral sympathetic nerve stimulation on cerebral blood flow (CBF) were examined in anesthetized rabbits (n = 7). CBF ranged from 32 to 50 ml/min per 100 g. Bilateral stimulation reduced blood flow by 17-31% to cerebrum, diencephalon-mesencephalon and cerebellum, and responses were constant between 2 and 6 min of stimulation. Sustained cerebral vasoconstriction is consistent with an important role for sympathetic nerves in the regulation of CBF.
D000818:Animals; D001794:Blood Pressure; D001921:Brain / Q000098:blood supply*; D005260:Female; D005728:Ganglia, Sympathetic; D011817:Rabbits; D012039:Regional Blood Flow; D014661:Vasoconstriction; D014666:Vasomotor System / Q000502:physiology*