Corneal sensitivity in myasthenia gravis.
Corneal touch thresholds were measured in 11 people suffering from myasthenia gravis (MG) and in a control group of 20 subjects. The mean threshold in MG was 75.6 mg (SD 52) and in the control group 18.9 mg (SD 7.3); thresholds were thus significantly (p less than 0.01) raised in MG. Although it is not possible to say whether the sensory deficit is due to MG or to the treatment, the results implicate acetylcholine in sensory transduction in the cornea.
D000328:Adult; D000368:Aged; D003315:Cornea / Q000503:physiopathology*; D005127:Eye Color; D006801:Humans; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000503:physiopathology*; D012684:Sensory Thresholds / Q000502:physiology; D014110:Touch