Simple method for prediction and estimation of the hemodialysability of incorporated drugs.
This paper describes a simple method for measuring the hemodialysability of incorporated drugs, including mathematical equations. The method furnishes preliminary drug data in early phase I investigation. Relevance of the obtained results is shown by comparison with the established literature.
D003956:Dialysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008722:Methods; D008954:Models, Biological; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011485:Protein Binding; D006435:Renal Dialysis; D012995:Solubility; D013329:Structure-Activity Relationship; D014462:Ultrafiltration
D004364:Pharmaceutical Preparations