title: Pre-operative sinus node function in adult patients with atrial septal defect (ostium secundum type).
abstract: The authors studied, pre-operatively, the sinus node function in adult patients with secundum atrial septal defect and large left-right shunts, using Holter ECG and electrophysiological tests. Sinus node electrophysiological tests were found abnormal in 17 out of 26 patients; on the contrary, Holter monitoring was always within normal limits. The authors believe that concealed sinus node dysfunction existing before surgical correction may be a cause of early, acute, and reversible, post-operative sick sinus syndrome.
mesh_terms: D000293:Adolescent; D000328:Adult; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography; D004594:Electrophysiology; D005260:Female; D006344:Heart Septal Defects, Atrial / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011183:Postoperative Complications / Q000209:etiology; D011300:Preoperative Care; D012804:Sick Sinus Syndrome / Q000209:etiology; D012849:Sinoatrial Node / Q000503:physiopathology*