A Golgi and morphometric study of the ectopic granule cells in the molecular layer of the rat cerebellum.
The morphological types of isolated ectopic granule cells (EGCs) were examined with Golgi-Rio Hortega staining in the cerebellar molecular layer of adult normal rats. The EGCs showed a significant reduction in the number of dendrites (mean 2.42 +/- 0.07) with respect to the controls (mean 3.97 +/- 0.09), and they usually exhibited poorly developed dendritic terminals. The karyometric analysis on semithin sections indicated that the average nuclear area in EGCs was significantly smaller (16.62 +/- 0.20 micron 2) than in normally positioned granule cells (21.08 +/- 0.24 micron 2).
D000818:Animals; D002465:Cell Movement; D002467:Cell Nucleus / Q000648:ultrastructure; D002525:Cerebellar Cortex / Q000166:cytology*; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains