[Permeability of the erythrocyte membrane for sodium in hypertension and symptomatic hypertension].
Sodium permeability of erythrocyte membranes was examined, using the recording of maximum rates of sodium-lithium countertransport, in patients with essential hypertension of stages II and III by the WHO classification, renal arterial hypertension, Itsenko-Cushing disease, pheochromocytoma, Conn's syndrome and in subjects with normal arterial pressure who made up a control group. Hypertensive patients demonstrated a more than 60% increase in erythrocyte membrane permeability, as compared to normotensive controls. In patients with pheochromocytoma, the permeability values were almost 40% as low as the control ones. No changes in sodium erythrocyte membrane permeability could be demonstrated in patients with renal hypertension, Itsenko-Cushing disease and Conn's syndrome. It is believed that the erythrocyte membrane permeability parameters can be used for the identification of essential hypertension in the differential diagnosis of hypertensions.
D000310:Adrenal Gland Neoplasms / Q000097:blood / Q000175:diagnosis; D000328:Adult; D002463:Cell Membrane Permeability; D003480:Cushing Syndrome / Q000097:blood / Q000175:diagnosis; D003937:Diagnosis, Differential; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood / Q000175:diagnosis; D006973:Hypertension / Q000097:blood* / Q000175:diagnosis; D006977:Hypertension, Renal / Q000097:blood / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010673:Pheochromocytoma / Q000097:blood / Q000175:diagnosis; D012964:Sodium / Q000097:blood*
D012964:Sodium
Pronitsaemost' membrany éritrotsitov dlia natriia pri gipertonicheskoĭ bolezni i simptomaticheskikh gipertenziiakh.