Effect of lubricant level and applied compressional pressure on surface friction of tablets.
A method for measuring friction coefficients of compacted surfaces (tablet surfaces) is described. Frictional coefficient measurements were carried out at various tableting compression forces. The effect of magnesium stearate concentration was found to be a log-linear approach to an asymptote (which would represent a minimum frictional coefficient).
D004339:Drug Compounding; D005079:Excipients; D008153:Lubrication; D010316:Particle Size; D011312:Pressure; D013229:Stearic Acids; D013395:Sucrose; D013499:Surface Properties; D013607:Tablets
D005079:Excipients; D013229:Stearic Acids; D013607:Tablets; C031183:stearic acid; D013395:Sucrose