title: Direct-vision sampling of chorionic villi during extra-amniotic instillation of physiologic saline solution: effect on intrauterine pressure and fetal heart activity.
abstract: After 150 ml of physiologic saline solution had been infused into the extra-amniotic space before first-trimester vacuum aspiration abortion, intrauterine pressure ranged between 16 and 23 mm Hg, thus not more than during Braxton Hicks contractions. At chorionic villi sampling during continuous saline solution infusion, fetal heart activity (beats per 15 seconds) decreased temporarily from about 36 to about 33.
mesh_terms: D000650:Amnion; D002824:Chorionic Villi / Q000473:pathology*; D005260:Female; D005318:Fetal Heart / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007267:Injections; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis / Q000379:methods*; D011312:Pressure; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage*; D012965:Sodium Chloride / Q000008:administration & dosage*; D014599:Uterus / Q000187:drug effects*
chemical_list: D012462:Saline Solution, Hypertonic; D012965:Sodium Chloride