[Oscillatory evoked potentials in the rabbit visual system during experimental retinal pathology induced by administration of monoiodoacetic acid].
ERG and EP of the visual cortex (VC) and superior colliculus (SC) were investigated under experimental dystrophy of the retina induced by intravenous injection of monoiodoacetic acid in different doses. The relative resistance of the VC to the derangement of retinal function was established. It was manifested by less marked suppression of its EP as compared with ERG. Taking into consideration the selective projection to the SC of the rod system that was damaged to a greater degree under pathology in question, it is suggested that functional suppression of the SC might facilitate the conduction of visual information through the main retino-geniculo-cortical canal. This might be one of the factors of VC resistance to the impairment of retinal function. This assumption was confirmed in experiments with SC electrocoagulation in which one could observe the facilitation of EP formation of the contralateral VC.
D000818:Animals; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D007461:Iodoacetates; D019807:Iodoacetic Acid; D011817:Rabbits; D012162:Retinal Degeneration / Q000139:chemically induced / Q000503:physiopathology*; D013477:Superior Colliculi / Q000503:physiopathology*; D014793:Visual Cortex / Q000503:physiopathology*
D007461:Iodoacetates; D019807:Iodoacetic Acid
Ostsilliatornye vyzvannye potentsialy v zritel'noĭ sisteme krolika pri éksperimental'noĭ patologii setchatki, sozdannoĭ vvedeniem monoïoduksusnoĭ kisloty.