The synthesis of prostaglandins by the Nb rat prostate tumor.
Carcinomata of the prostate animal model systems have been used in the past to evaluate chemotherapy. The Nb rat model is an ideal model to study prostate cancer, as it has two separate tumor types, one that is androgen-insensitive and one that is androgen-sensitive. In this paper the results of the prostaglandin synthesis release assay on an antigen-insensitive tumor are presented. This is a means to further characterize this tumor.
D000230:Adenocarcinoma / Q000378:metabolism*; D000818:Animals; D001095:Arachidonic Acids / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D011453:Prostaglandins / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000378:metabolism*; D051381:Rats
D001095:Arachidonic Acids; D011453:Prostaglandins