Uveitis associated with poliosis and vitiligo in six dogs.
Idiopathic panuveitis with retinal detachment was associated with facial poliosis, vitiligo, and alopecia in 6 dogs; 4 were adult males. Dermatohistologic examination of affected facial sites from all dogs revealed a lichenoid dermatitis and unusual histiocytic cells. Intensive topical and systemic corticosteroid and topical mydriatic/cycloplegic therapy was successful in controlling uveitis in all dogs for variable periods. Three dogs, monitored for 12, 30, and 46 months, retained useful vision despite infrequent recurrence of uveitis. One dog was lost for subsequent examination. Two dogs were euthanatized and necropsied. Ocular histologic examination of these dogs revealed extensive granulomatous iridocyclitis and choroiditis, with retinal detachment and lenticular degeneration.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D004283:Dog Diseases / Q000188:drug therapy / Q000473:pathology*; D004285:Dogs; D005123:Eye / Q000473:pathology; D005260:Female; D006201:Hair Diseases / Q000662:veterinary*; D008297:Male; D009184:Mydriatics / Q000627:therapeutic use; D010859:Pigmentation Disorders / Q000662:veterinary*; D012163:Retinal Detachment / Q000662:veterinary; D012867:Skin / Q000473:pathology; D013577:Syndrome / Q000662:veterinary; D014605:Uveitis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D014820:Vitiligo / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
D000305:Adrenal Cortex Hormones; D009184:Mydriatics