Ascending responses induced by transmural nerve stimulation in the cat duodenum.
Electromyographic responses of the cat duodenum were recorded in vitro up to 5 cm oral to the site of transmural nerve stimulation. Repetitive stimulation induced ascending cholinergic and non-cholinergic excitatory responses characterized by an increase in the slow wave amplitude and spiking activity. Ascending inhibitory responses were also recorded and were characterized by a suppression of the spiking activity and a decrease in the slow wave amplitude. The ascending cholinergic excitatory response was abolished by atropine. The non-cholinergic excitatory and inhibitory responses both disappeared in the presence of tetrodotoxin.
D000818:Animals; D002415:Cats; D002799:Cholinergic Fibers / Q000502:physiology; D004386:Duodenum / Q000294:innervation* / Q000502:physiology; D004558:Electric Stimulation; D004576:Electromyography; D005071:Evoked Potentials; D005260:Female; D005769:Gastrointestinal Motility; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction; D009132:Muscles / Q000502:physiology*