title: [Comparative characteristics of the adrenal and gonadal functions in human beings and hamadryas baboons with hemoblastosis].
abstract: Adrenal and gonad steroid hormones were investigated in the peripheral blood plasma of human beings and hamadryas baboons (Papio hamadryas) with hemoblastosis. The similar hormonal dysfunction of adrenal glands and gonads was found in human beings and monkeys. The dehydroepiandrosterone level was found to decrease significantly, while the cortisol level increased markedly. Changes in the androgen level were sex-dependent. The testosterone and 5 alpha-dihydrotestosterone levels were found to decrease markedly in men and male baboons while the testosterone level in women and females was found to increase significantly with 5 alpha-dihydrotestosterone unchanged.
mesh_terms: D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000097:blood; D000311:Adrenal Glands / Q000503:physiopathology*; D000328:Adult; D000368:Aged; D000818:Animals; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D007938:Leukemia / Q000097:blood / Q000503:physiopathology*; D007942:Leukemia, Experimental / Q000097:blood / Q000503:physiopathology*; D007945:Leukemia, Lymphoid / Q000097:blood / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010053:Ovary / Q000503:physiopathology*; D013737:Testis / Q000503:physiopathology*
chemical_list: D000305:Adrenal Cortex Hormones; D012739:Gonadal Steroid Hormones
vernacular_title: Sravnitel'naia kharateristika gormonal'noĭ funktsii nadpochechnikovykh i polovykh zhelez u liudeĭ i pavianov gamadrilov, bol'nykh gemoblastozom.