Hemostatic changes after saline infusion.
An in vitro trial was performed to detect a thrombotic tendency in patients receiving saline infusions before surgery. The following tests were performed: thromboelastography (TEG) with the three indices of the reaction time (r), clot formation time (k) and maximum amplitude (MA), and antithrombin III, which was investigated immunologically as well as by a functional test with a chromogenic substrate and an automated method. The use of these tests together with others for the detection of high-risk patients is suggested, since no single laboratory test was found to be sufficient for the prediction of thrombotic diseases.
D000990:Antithrombin III / Q000032:analysis; D006438:Hemodilution; D006487:Hemostasis; D006801:Humans; D066298:In Vitro Techniques; D007263:Infusions, Parenteral; D011183:Postoperative Complications; D011300:Preoperative Care; D012965:Sodium Chloride / Q000008:administration & dosage* / Q000009:adverse effects; D013916:Thrombelastography; D013927:Thrombosis / Q000097:blood / Q000209:etiology
D012965:Sodium Chloride; D000990:Antithrombin III