title: Usefulness of left ventricular volume in assessing tetralogy of Fallot for total correction.
abstract: Ninety-one patients with tetralogy of Fallot underwent intracardiac repair between 1978 and 1981. One patient died from left-sided heart failure. Retrospective analyses of this death revealed a significant decrease of the left ventricular (LV) end-diastolic volume index (EDVI) of 21 ml/m2 (36% of normal). Results of early postoperative hemodynamic studies after total correction of this anomaly suggested that an EDVI of 30 ml/m2 is the minimal requirement for adequate cardiac output postoperatively. Based on these data, 3 patients with decreased LV volume with EDVI of around 30 ml/m2 were challenged with the primary repair with success, although they required atrial pacing and catecholamine support postoperatively to maintain adequate left atrial pressure and cardiac output. From these results, it is recommended that patients with tetralogy of Fallot and an EDVI of 30 ml/m2 or more can be considered as candidates for the primary repair, but that patients with an EDVI of less than 30 ml/m2 should be palliated once by systemic-to-pulmonary arterial shunt procedures. Subsequent total correction should be performed after sufficient LV growth for those patients.
mesh_terms: D000293:Adolescent; D002302:Cardiac Output; D002306:Cardiac Volume; D002648:Child; D002675:Child, Preschool; D003971:Diastole; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011184:Postoperative Period; D013318:Stroke Volume; D013771:Tetralogy of Fallot / Q000503:physiopathology / Q000601:surgery*; D016276:Ventricular Function