Constituents of Erysimum inconspicuum. Two sulfur-containing lactone compounds.
The alcohol extract of Erysimum inconspicuum fruits, which exhibited cytotoxic activity against the KB cell line and some activity against the P-388 lymphocytic leukemia in vivo, was studied. Strophanthidin, uzarigenin, and two sulfur-containing lactones, erysulfone[6-methylsulfonyl-4-hydroxyhexanoic acid lactone] and erysulfoxide[6-methylsulfinyl-4-hydroxyhexanoic acid lactone], were isolated and characterized by spectral data.
D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D006801:Humans; D007624:KB Cells / Q000187:drug effects; D007783:Lactones / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000032:analysis; D010946:Plants, Medicinal / Q000032:analysis*; D013327:Strophanthidin / Q000032:analysis
D000972:Antineoplastic Agents, Phytogenic; D007783:Lactones; D010936:Plant Extracts; D013327:Strophanthidin; C046354:erysulfone; C046353:erysulfoxide