Analysis of anthralin in dermatological products by reversed-phase high-performance liquid chromatography.
A reversed-phase liquid chromatographic method is described for the determination of anthralin in topical products. The factors affecting the degradation of anthralin solid and solutions are discussed. Ultraviolet spectra of degradation products are presented. The assay method has been thoroughly optimized and is shown to be specific, precise, and accurate.
D000873:Anthracenes / Q000032:analysis*; D000875:Anthralin / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D003879:Dermatologic Agents / Q000032:analysis*; D007202:Indicators and Reagents; D013056:Spectrophotometry, Ultraviolet
D000873:Anthracenes; D003879:Dermatologic Agents; D007202:Indicators and Reagents; D000875:Anthralin