[Value of oral primperan in the treatment of migraine].
The association of Primperan with antimigrainous drugs, such as salicylates and paracetamol, can reduce the duration of the migraine. The mechanism of this action is studied: by accelerating the gastric emptying, which is delayed during the migraine attack, Primperan enables the analgesics to reach their site of absorption more rapidly and, consequently, to be more rapidly effective. The activity of the oral administration of Primperan is demonstrated.
D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use; D005746:Gastric Emptying / Q000187:drug effects; D006801:Humans; D008787:Metoclopramide / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008881:Migraine Disorders / Q000188:drug therapy*
D008787:Metoclopramide; D001241:Aspirin
Apport du primpéran par voie orale au traitement de la migraine.