title: Haploid expression of a unique c-abl transcript in the mouse male germ line.
abstract: RNA from immature mouse testes was shown to lack a low-molecular-weight c-abl transcript previously noted to be the predominant species in adult testes. The developmental pattern of appearance of this c-abl variant was determined by analyzing RNA obtained from purified populations of testicular cells in different stages of spermatogenesis. The appearance of the c-abl testicular variant was coincident with the entry of the germ cells into their haploid state and suggested that the regulated expression of this proto-oncogene may be important in the normal differentiation of the male germ line.
mesh_terms: D000818:Animals; D008297:Male; D051379:Mice; D009857:Oncogenes; D012333:RNA, Messenger / Q000235:genetics; D012741:Sexual Maturation; D013090:Spermatocytes / Q000502:physiology; D013091:Spermatogenesis; D013737:Testis / Q000502:physiology*
chemical_list: D012333:RNA, Messenger