Pituitary apoplexy in an acromegalic patient during bromocriptine therapy. Case report.
The authors report a case of pituitary apoplexy that developed in a patient shortly after bromocriptine therapy was started for a growth hormone-secreting pituitary adenoma. The tumor was associated with visual impairment and ocular palsies, and was treated by transsphenoidal decompression. Although spontaneous tumor necrosis cannot be excluded, a causal role of bromocriptine treatment is suggested.
D000236:Adenoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology; D001971:Bromocriptine / Q000009:adverse effects* / Q000627:therapeutic use; D002561:Cerebrovascular Disorders / Q000139:chemically induced*; D004702:Endocrine Glands / Q000503:physiopathology; D005260:Female; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D008875:Middle Aged; D010902:Pituitary Gland / Q000098:blood supply*; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
D001971:Bromocriptine; D013006:Growth Hormone