[Invasive aspergillosis in patients who died from acute leukemia].
The necropsy material with acute leukosis (166 deceased) was studied in order to establish the incidence of invasive aspergillosis. It was established in 16 of the deceased (9,64%): aspergillosis pneumonia--in 5 cases, aspergillosis sepsis--in II, with invasion of lungs, brain, spleen, liver, myocardium and other organs. Clinically aspergillosis was not distinguished. Continuous septic temperature, not influenced by antibiotic therapy should draw the attention to the presence of aspergillosis. The factors, preconditioning aspergillosis infection are stressed upon: immune-suppressive treatment in acute leukosis, granulocytopenia, continuous preceding antibiotic therapy, etc. The difficulties in the clinical differentiation of the infection are emphasized. With a view to the high incidence and lethality of aspergillosis in acute leukosis, the introduction of modern diagnostic methods and treatment are underlined to be necessary.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001228:Aspergillosis / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007938:Leukemia / Q000150:complications / Q000473:pathology*; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000473:pathology; D011014:Pneumonia / Q000175:diagnosis / Q000473:pathology; D011446:Prospective Studies; D012189:Retrospective Studies
Invazivna aspergiloza u pochinali s ostra levkoza.