Hemorrheology of marathon running.
The hemorheological effects of severe exertion were evaluated in eight males and six females before and after a marathon. A highly significant fall in red cell filterability (RCF) was accompanied by a significant rise in plasma osmolality. This correlation was further studied by a series of in vitro experiments to establish a cause-effect relationship. As plasma osmolality increased, RCF progressively diminished. These observations demonstrate that plasma hyperosmolality is an important etiological factor in reducing RCF during strenuous exercise.
D000328:Adult; D004907:Erythrocyte Deformability; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D005082:Physical Exertion; D012212:Rheology; D012420:Running; D014882:Water-Electrolyte Balance