Assignment of uroporphyrinogen decarboxylase (UROD) to the pter----p21 region of human chromosome 1.
The assignment of the human gene for uroporphyrinogen decarboxylase (UROD) to chromosome 1 is confirmed and further localized to the pter----p21 region through the use of human-mouse somatic cell hybrids. Human and mouse UROD were separated by electrophoresis and identified with antibodies to the human enzyme after electrophoretic transfer to nitrocellulose membranes.
D000818:Animals; D000906:Antibodies; D000936:Antigen-Antibody Complex; D002262:Carboxy-Lyases / Q000235:genetics*; D002460:Cell Line; D002874:Chromosome Mapping; D002900:Chromosomes, Human, 1-3; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology / Q000201:enzymology; D051379:Mice; D014575:Uroporphyrinogen Decarboxylase / Q000235:genetics*
D000906:Antibodies; D000936:Antigen-Antibody Complex; D002262:Carboxy-Lyases; D014575:Uroporphyrinogen Decarboxylase