[Effect of courses of acetylsalicylic acid and sodium salicylate administration on the carbohydrate-phosphorus metabolic indices in vascular tissue].
Experiments on 78 adult rats were made to study the effects of acetylsalicylic acid and sodium salicylate administered daily for 7 and 14 days on the content of pyruvic, lactic, citric acids and inorganic phosphate in the wall of blood vessels of different function. Salicylates were demonstrated to reduce the content of citric acid by the 7th day and that of pyruvic acid by the 14th day, to increase the level of lactate and inorganic phosphorus during both observation periods. The degree of the changes revealed is unequal in different vessels, being more pronounced after sodium salicylate administration.
D000818:Animals; D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology*; D001808:Blood Vessels / Q000187:drug effects* / Q000378:metabolism; D050260:Carbohydrate Metabolism; D005260:Female; D008297:Male; D010758:Phosphorus / Q000378:metabolism*; D051381:Rats; D012980:Sodium Salicylate / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D010758:Phosphorus; D001241:Aspirin; D012980:Sodium Salicylate
Vliianie kursovykh vvedeniĭ atsetilsalitsilovoĭ kisloty i natriia salitsilata na pokazateli uglevodno-fosfornogo obmena v sosudistoĭ tkani.