[Measurement of uteroplacental circulation with 113m indium in diabetic pregnancy].
In 122 diabetic pregnancies the placental blood flow has been estimated determining the half life of the activity inflow (2 MBq 113 m In labelled transferrin) into the placental bed. We used a highly sensitive detector (modified pinhole collimator) and a computer supported evaluation, free from subjective influences. 259 flow measurements were compared to the risk of complication in the course of a diabetic pregnancy. - The half life values in the diabetic group, calculated by a gamma camera computer system by means of an iterative regression analysis, were significantly different compared to a control group (12 pregnancies without risk.) - Severe diabetic angiopathic complications (White classes D, F, and R) are accompanied by higher half life values (placental blood flow reductions) and perinatal complications. - Even in pregnant women with gestational diabetes or disturbances of the carbohydrate metabolism a disturbed placental hemodynamic is to be found.
D000328:Adult; D003925:Diabetic Angiopathies / Q000000981:diagnostic imaging; D005260:Female; D005865:Gestational Age; D005951:Glucose Tolerance Test; D006801:Humans; D007204:Indium; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000098:blood supply*; D010927:Placental Insufficiency / Q000000981:diagnostic imaging; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000000981:diagnostic imaging*; D011868:Radioisotopes; D011877:Radionuclide Imaging; D014599:Uterus / Q000098:blood supply*
D011868:Radioisotopes; D007204:Indium
Die Messung der uteroplazentaren Durchblutung mit 113m In in der diabetischen Schwangerschaft.