Effect of blood pressure on A2 noradrenergic neurons.
Single-unit recordings of A2 noradrenergic neurons were obtained in urethane-anesthetized rats. Norepinephrine-induced elevations in arterial pressure produced small decreases in the discharge rate of the cells; this effect was not observed in animals with bilateral sections of the ninth and tenth nerves. The activity of A2 cells was neither pulse-synchronous at high levels of arterial pressure nor significantly affected by carotid stretch. It is concluded that these neurons do not receive a significant baroreceptor input.
D000818:Animals; D001127:Arginine Vasopressin / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D001923:Brain Chemistry / Q000187:drug effects; D004594:Electrophysiology; D005071:Evoked Potentials / Q000187:drug effects; D008297:Male; D009475:Neurons, Afferent / Q000502:physiology*; D009638:Norepinephrine / Q000494:pharmacology; D011311:Pressoreceptors / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D011930:Reaction Time
D001127:Arginine Vasopressin; D009638:Norepinephrine