The release of lyso-PAF from guinea-pig lungs.
Lyso-PAF was detected after ionophore challenge in the effluent of lungs of guinea-pigs exposed to oxygen and perfused through the pulmonary circulation as well as of control lungs perfused through the airways. Lyso-PAF is probably the inactive metabolite of PAF-acether which could not, itself, be detected in the lung effluents.
D000818:Animals; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008168:Lung / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010100:Oxygen / Q000633:toxicity; D010477:Perfusion; D010972:Platelet Activating Factor / Q000031:analogs & derivatives* / Q000378:metabolism
C029271:O-deacetyl platelet activating factor; D010972:Platelet Activating Factor; D010100:Oxygen