Alterations in catecholamine metabolism partially corrected during amphetamine-dependence.
A woman appeared to clinically benefit from high doses of amphetamine taken for a period of 27 years. During amphetamine administration, elevated urinary 3-methoxy-4-hydroxy-phenylglycol (MHPCG) excretion values returned to normal accompanied by reductions in plasma phenylalanine.
D000328:Adult; D000661:Amphetamine / Q000627:therapeutic use*; D001927:Brain Diseases / Q000150:complications / Q000188:drug therapy*; D002395:Catecholamines / Q000172:deficiency*; D005260:Female; D006801:Humans; D019965:Neurocognitive Disorders / Q000150:complications / Q000188:drug therapy; D012651:Self Medication; D019966:Substance-Related Disorders / Q000150:complications*
D002395:Catecholamines; D000661:Amphetamine