title: [Kasabach-Merritt syndrome in infants. 2 cases].
abstract: Two infants presenting with Kasabach-Merritt syndrome point out several points: the hemangioma may look innocuous with small proportions. The coagulopathy may be represented by a simple thrombopenia or an intravascular coagulation (PDF, ethanol test) of bad prognosis. A review of 150 observations of Kasabach-Merritt syndrome suggests a simple therapeutic approach: corticotherapy (2 to 4 mg/kg) for 2 to 4 weeks or, if failure, antiaggregant drugs. Radiotherapy is proposed in cases of emergency. Heparin and antifibrinolytic treatments are restricted to cases with severe coagulopathy.
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011696:Purpura, Thrombocytopenic / Q000175:diagnosis* / Q000628:therapy; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000628:therapy; D013577:Syndrome; D013997:Time Factors
vernacular_title: Syndrome de Kasabach-Merritt du nourrisson. Deux observations.