title: Acid phosphatase activity of cerebrospinal fluid cells in leptomeningeal haemorrhage.
abstract: One hundred and twenty samples of haemorrhagic spinal fluid were examined by acid phosphatase staining. This enzyme activity starts to appear in mono-histiocytic cells 2 days after bleeding and increases up to the 5th day. After 1 week the activity decreases rapidly. Similar results are found in mixtures of incubated clear spinal fluid, to which blood is added. Acid phosphatase staining is a useful additional method for determination of the age of a leptomeningeal bleed.
mesh_terms: D000135:Acid Phosphatase / Q000134:cerebrospinal fluid*; D002543:Cerebral Hemorrhage / Q000201:enzymology*; D002555:Cerebrospinal Fluid / Q000166:cytology; D006801:Humans; D008264:Macrophages / Q000201:enzymology; D009000:Monocytes / Q000201:enzymology; D010586:Phagocytes / Q000201:enzymology; D010587:Phagocytosis
chemical_list: D000135:Acid Phosphatase