title: [Age-related aspects of intensive therapy of acute poisoning of chemical etiology].
abstract: Assay of the clinical course of poisoning with acetic acid, dichloroethane, carbophos, chlorophos, phenobarbital and sodium etaminal in 2538 patients made it possible to define, with the use of the probit analysis, the 25, 50, 75 and 95% concentration thresholds of the lethality in acute poisonings with acetic acid, carbophos and dichloroethane. It was established that under exposure to the toxic substances undergoing different chemical changes in the body, the increase of the lethality risk varied in different age groups. The differences in the structure of outcomes in patients of different age groups formed the basis for making up a classification of the toxicity of the chemical compounds. The differences revealed require a differential approach to the determination of the scope of intensive care of poisonings in terms of the age-associated features.
mesh_terms: D000085:Acetates / Q000506:poisoning; D019342:Acetic Acid; D000208:Acute Disease; D000328:Adult; D000367:Age Factors; D003422:Critical Care / Q000379:methods*; D005025:Ethylene Dichlorides / Q000506:poisoning; D006464:Hemoperfusion; D006801:Humans; D008294:Malathion / Q000506:poisoning; D008875:Middle Aged; D010424:Pentobarbital / Q000506:poisoning; D010634:Phenobarbital / Q000506:poisoning; D011041:Poisoning / Q000628:therapy*; D006435:Renal Dialysis
chemical_list: D000085:Acetates; D005025:Ethylene Dichlorides; D010424:Pentobarbital; D019342:Acetic Acid; D008294:Malathion; D010634:Phenobarbital
vernacular_title: Vozrastnye aspekty intensivnoĭ terapii ostrykh otravleniĭ khimicheskoĭ etiologii.