Reye syndrome associated with aspirin therapy for systemic lupus erythematosus.
A 14-year-old girl in whom Reye syndrome developed during aspirin therapy for an inflammatory disorder proven to be systemic lupus erythematosus is reported. This case and similar cases of Reye syndrome in patients with juvenile rheumatoid arthritis suggest that an etiologic relationship exists between salicylate therapy and Reye syndrome in children with collagen vascular disorders.
D000293:Adolescent; D000641:Ammonia / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use; D001707:Biopsy, Needle; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007427:Intracranial Pressure / Q000187:drug effects; D008099:Liver / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy*; D008854:Microscopy, Electron; D012202:Reye Syndrome / Q000139:chemically induced* / Q000473:pathology
D000641:Ammonia; D001219:Aspartate Aminotransferases; D001241:Aspirin