The measurement of 2,3-butanediol and 1,2-propanediol in "flushing" and "non-flushing" Japanese.
Seven Japanese medical students, three "flushers" and four "non-flushers," were given 0.5 g ethanol/kg body weight PO in an attempt to assess whether elevated body acetaldehyde can account for 2,3-butanediol production in humans. Blood was taken from the anticubital vein immediately prior to, 30, 60, 90, and 120 min after ingestion of ethanol. No difference in the two groups was observed in 2,3-butanediol or in 1,2-propanediol. Measured 1,2-propanediol was in the normal range in both groups. No 2,3-butanediol was detected in any of the subjects.
D000328:Adult; D002072:Butylene Glycols / Q000097:blood*; D000431:Ethanol / Q000097:blood; D005483:Flushing / Q000139:chemically induced*; D006801:Humans; D019946:Propylene Glycol; D011409:Propylene Glycols / Q000097:blood*; D011674:Pulse; D013997:Time Factors
D002072:Butylene Glycols; D011409:Propylene Glycols; D000431:Ethanol; C026978:2,3-butylene glycol; D019946:Propylene Glycol