[Local blood flow into tumors during artificial hyperglycemia].
The blood flow in the rat Guerin carcinoma was measured by the hydrogen clearance method. It was shown that the blood flow in the tumour tissue decreased almost 3.5 times to the 3 hours of the intravenous glucose infusion at a dose of 80 mg X kg-1 X min-1. In some tumours the microcirculation ceased completely. The results obtained help developing the new schemes of local hyperthermia and induced hyperglycemia in the complex antitumour therapy.
D000818:Animals; D005260:Female; D006859:Hydrogen / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D006943:Hyperglycemia / Q000503:physiopathology*; D008297:Male; D008657:Metabolic Clearance Rate / Q000187:drug effects; D008722:Methods; D008833:Microcirculation / Q000503:physiopathology; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000098:blood supply* / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D006859:Hydrogen
Lokal'nyĭ krovotok v opukholi pri iskusstvennoĭ giperglikemii.