title: The influence of the pH value of the synovial fluid on the articular cartilage in rabbits. A scanning electron microscopic study.
abstract: After the intraarticular injection of isoosmolaric buffer solutions with pH values of 4.0 and 10.0 or 7.3 (control side) into the knee joints of rabbits the appearance of a fibrillated network on a plane parallel to the surface and tears in the articular cartilage are seen with the aid of scanning electron microscopy. The results are interpreted as a damage of the superficial layer of the articular cartilage. In a long-term follow up only the growing rabbits are able to repair these lesions, the adult animals are not capable to do it.
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000254:growth & development / Q000502:physiology* / Q000648:ultrastructure; D006863:Hydrogen-Ion Concentration; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D013582:Synovial Fluid / Q000502:physiology*; D013997:Time Factors