title: Localization of the alpha and beta casein genes to the q24 region of chromosome 12 in the rabbit (Oryctolagus cuniculus L.) by in situ hybridization.
abstract: The syntenic alpha and beta casein genes were localized in the rabbit by chromosomal in situ hybridization, using a mixture of two radioactive cDNA probes corresponding to these two genes. Highly significant labeling was observed on chromosome 12. A total of 175 silver grains was found on chromosomes in the 193 mitoses studied; 18% of the grains were on chromosome 12, and 42% of the grains on this chromosome were localized to the 12q24 region. Statistical analysis revealed that this labeling was highly significant.
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002364:Caseins / Q000235:genetics*; D002478:Cells, Cultured; D002874:Chromosome Mapping; D005347:Fibroblasts / Q000166:cytology; D005796:Genes; D007621:Karyotyping; D008677:Metaphase; D009693:Nucleic Acid Hybridization; D011817:Rabbits
chemical_list: D002364:Caseins