title: Pheromone-induced reproductive inhibition in young female Peromyscus leucopus.
abstract: Soiled bedding and urine from adult female white-footed mice (Peromyscus leucopus) were tested for their capacity to inhibit reproduction of young females. Test animals were given either physical or airborne contact with soiled bedding from adult females, adult female urine, clean bedding, or water from 21 to 150 days of age. Results indicate that reproductive inhibition is due to an airborne pheromone emitted by the adult females as a component of their urine. In the second experiment, young female mice were exposed to an adult female for 0, 1, 3, 6, 12, 18, or 24 h/day from 21 to 150 days of age. Results from this experiment show that exposure to adult females of as little as 3 h/day was sufficient to cause reproductive inhibition to occur. This phenomenon has important implications in terms of both female-female reproductive competition and socially mediated population regulation.
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D010542:Peromyscus / Q000502:physiology*; D010675:Pheromones; D011247:Pregnancy; D012098:Reproduction
chemical_list: D010675:Pheromones