Varying rates of alcohol metabolism in relation to detoxification medication.
Fifteen patients admitted for alcohol dependency had serial blood alcohol levels drawn. The rate of metabolism was calculated a number of different ways and this was compared to the amount of Librium required for the initial period of withdrawal. It was found that the alcoholics' average metabolism was 26.6 mg%/hour. Although there was a tendency for those with high initial blood alcohol levels to have faster metabolisms, there was not a significant correlation between the two features. There was correlation between the amount of Librium used in the initial period of detoxification and the initial blood alcohol concentration.
D000437:Alcoholism / Q000097:blood; D002707:Chlordiazepoxide / Q000627:therapeutic use; D000431:Ethanol / Q000097:blood*; D006801:Humans; D008657:Metabolic Clearance Rate; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*
D000431:Ethanol; D002707:Chlordiazepoxide