Testosterone-estradiol-binding globulin binds to human prostatic cell membranes.
Specific binding sites for human testosterone-estradiol-binding globulin have been found on human prostatic cell membranes. Scatchard analysis reveals both a high and a low affinity binding site for [125I]testosterone-estradiol-binding globulin. The high affinity site is specific for testosterone-estradiol-binding globulin, whereas the low affinity site also binds human corticosteroid-binding globulin and human transferrin.
D001665:Binding Sites; D001667:Binding, Competitive; D002462:Cell Membrane / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism; D006801:Humans; D007700:Kinetics; D008297:Male; D011467:Prostate / Q000166:cytology*; D012709:Serum Albumin / Q000378:metabolism; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism*; D013739:Testosterone / Q000378:metabolism; D014156:Transcortin / Q000378:metabolism; D014168:Transferrin / Q000378:metabolism
D012709:Serum Albumin; D012738:Sex Hormone-Binding Globulin; D014168:Transferrin; D013739:Testosterone; D004958:Estradiol; D014156:Transcortin