Histochemical localization of acetylcholinesterase in blood cells.
Cholinesterase activity was detected by histochemical methods in normal human blood smears. In erythrocytes, acetylcholinesterase was found to be localized in the cortical region of the cells and, to a lesser degree, in the inner cytoplasm. In leucocytes, cholinesterase activity was found around the nuclear membrane and in the cytoplasm. The specificity of the enzymic activity was ascertained by using selective inhibitors.
D000110:Acetylcholinesterase / Q000032:analysis*; D000328:Adult; D002800:Cholinesterase Inhibitors / Q000494:pharmacology; D003593:Cytoplasm / Q000201:enzymology; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D005404:Fixatives; D006651:Histocytochemistry; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008297:Male; D009685:Nuclear Envelope / Q000201:enzymology
D002800:Cholinesterase Inhibitors; D005404:Fixatives; D000110:Acetylcholinesterase