Nasal mucosal blood flow in atrophic rhinitis.
Among many theories about the etiology of atrophic rhinitis with ozena, a reduced mucosal blood flow has been suggested, possibly caused by 'sympathetic spasm'. The nasal mucosal blood flow has been investigated in 6 patients with this disease before and after topical administration of a sympathomimetic drug. No difference in action compared to healthy subjects was found. Other pathophysiological mechanisms must be searched for.
D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000098:blood supply*; D010109:Oxymetazoline / Q000494:pharmacology; D012039:Regional Blood Flow / Q000187:drug effects; D012222:Rhinitis, Atrophic / Q000503:physiopathology*; D013566:Sympathomimetics / Q000494:pharmacology
D013566:Sympathomimetics; D010109:Oxymetazoline