title: Patterns of flap recurrence following mastectomy.
abstract: Flap recurrence after mastectomy is divisible into three distinct entities: spot recurrence, multiple spot recurrence and field change. Spot recurrence and multiple spot recurrence are usually controlled by local measures and are not associated with any particular characteristics of the primary tumour. The field change type of flap recurrence is difficult to control and is associated with aggressive primary tumours (grade III, node positive, oestrogen receptor negative) and a very poor prognosis. The appearance of field change type of flap recurrence is an indication for systemic therapy.
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D006801:Humans; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000628:therapy; D011379:Prognosis