title: Lethal and behavioral effects of chlordimeform in bobwhite.
abstract: The 7-day LC50 of chlordimeform to bobwhite (Colinus virginianus) chicks was 2835 ppm (95% CI = 2169-3705 ppm). Bobwhite chicks fed 1000 ppm (approximately LC4) chlordimeform for 7 days ate less, weighed less, travelled farther from a fright stimulus in an avoidance test, and had significantly more groups make greater than or equal to 10 light beam interruptions in an open-field test at 8 days of age than bobwhite fed 0, 1, 10, or 100 ppm chlordimeform (P less than or equal to 0.05). Groups fed 100 ppm (P less than or equal to 0.05) and 1000 ppm (P = 0.11) for 7 days crossed more often from the shallow to deep side of a visual cliff at 8 days of age than birds fed lesser concentrations of chlordimeform. Bobwhites were retested at 15 days of age, after being fed untreated diets for 7 days following the chlordimeform diets. The 1000 ppm group still travelled greater distances in the avoidance test (P less than or equal to 0.05). But open-field and visual cliff performances were similar to controls and other treatment groups. Chlordimeform concentrations causing behavioral aberrations in bobwhite were appreciably higher than environmental concentrations following field applications of chlordimeform.
mesh_terms: D000578:Amidines / Q000633:toxicity*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D002742:Chlorphenamidine / Q000633:toxicity*; D003088:Colinus / Q000502:physiology*; D004032:Diet; D004305:Dose-Response Relationship, Drug; D004924:Escape Reaction / Q000187:drug effects; D005247:Feeding Behavior / Q000187:drug effects; D009043:Motor Activity / Q000187:drug effects; D011784:Quail / Q000502:physiology*
chemical_list: D000578:Amidines; D002742:Chlorphenamidine