'Superpolyamines'. Macrocyclic polyamines induce highly efficient actin polymerization.
Macrocyclic polyammonium ions induce much more efficient polymerization of actin than the natural polyamines, behaving thus as 'superpolyamines'. The processes observed display large increases in rate, marked structural dependence, macrocyclic and ditopic binding effects and positive cooperativity.
D000199:Actins / Q000378:metabolism*; D000494:Allosteric Regulation; D001704:Biopolymers; D002942:Circular Dichroism; D007700:Kinetics; D046911:Macromolecular Substances; D011073:Polyamines / Q000378:metabolism*; D011485:Protein Binding; D000644:Quaternary Ammonium Compounds
D000199:Actins; D001704:Biopolymers; D046911:Macromolecular Substances; D011073:Polyamines; D000644:Quaternary Ammonium Compounds