[Parallel morphological and functional research on chronic enterocolitis patients using the authors' own method for the simultaneous performance of perfusion and biopsy of the small intestine].
Thirty two patients were studied with chronic enterocolitis and 9 patients without any small intestinal diseases, with normal histomorphological picture of small intestinal mucosa--control group. The method of simultaneous performance of perfusion and biopsy of small intestine was used. Glucose resorption rate in small intestine was studied and histomorphological, electron--microscopic and enzymologic (disaccharidases) studies were carried out on jejunal mucosa. Data about chronic enterocolitis without atrophy were established in 17 patients, in 10--initial partial atrophy, in 5--advanced partial and subtotal atrophy of jejunal mucosa. Reduced glucose resorption rate was established in small intestine in the patients with chronic enterocolitis as compared with that of the control group. Glucose resorption rate correlates with the severity of the histomorphological changes in small intestinal mucosa. Disturbed resorption rate was established via jejuno--perfusion in patients with clinically not manifested syndrome of malresorption and absence of histomorphological changes in small intestinal mucosa, but with established ultrastructural changes in enterocytes.
D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods; D002908:Chronic Disease; D004760:Enterocolitis / Q000503:physiopathology*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000503:physiopathology; D007421:Intestine, Small / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010477:Perfusion / Q000379:methods
D005947:Glucose
Paralelni morfologichni i funktsionalni izsledvaniia pri bolni s khronichen enterokolit s pomoshtta na sobstven metod za ednovremenno izvŭrshvane na perfuziia i biopsiia na tŭnko chervo.