[Electrophoretic control of serum proteins in donors designated for plasmapheresis. Initial evaluation of the analysis of 3500 donors].
Total serum proteins were evaluated and serum protein electrophoresis performed on 3 500 blood donors after plasmapheresis. The results were standard for total serum proteins, serum albumin and immunoglobulin in 98% of the donors, whereas monoclonal immunoglobulin, immunodeficiencies or polyclonal hypergammaglobulinemia were detected in 2% of them. The frequency of monoclonal components is roughly 0.3%, corresponding to the frequency observed in normal adults of 40 to 60 years old. Donors found with monoclonal immunoglobulins or immunodeficiency should not be considered as eligible for blood donation.
D000328:Adult; D000911:Antibodies, Monoclonal / Q000097:blood; D001782:Blood Donors; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000032:analysis*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis; D012709:Serum Albumin / Q000032:analysis
D000911:Antibodies, Monoclonal; D001798:Blood Proteins; D007136:Immunoglobulins; D012709:Serum Albumin
Contrôle électrophorétique des protéines sériques chez les donneurs prélevés par plasmaphérèse. Premier bilan de l'analyse de 3500 donneurs.