Genotype identification of 10-day old Zucker rats by lipid content of inguinal fat pad.
Surgical biopsies of the inguinal fat pad were performed on 35 fa/fa and 40 Fa/fa pups, aged 10 days, from eight litters. The lipid content of the pad, expressed as a percentage of the mean in each litter, allowed a 100 percent reliable prediction of the genotype. In three of the eight litters, we compared this method with that based on the frequency distribution of adipocyte size.
D000273:Adipose Tissue / Q000378:metabolism* / Q000473:pathology; D000818:Animals; D001835:Body Weight; D005838:Genotype; D006119:Groin; D050356:Lipid Metabolism; D009765:Obesity / Q000235:genetics; D051381:Rats; D011922:Rats, Mutant Strains / Q000235:genetics*; D011924:Rats, Zucker / Q000235:genetics*