Receptive field size of hair follicle afferents in rats treated neonatally with capsaicin.
Receptive field parameters of G- and D-hair units were investigated in adult rats given capsaicin as neonates. An air jet stimulator mounted on a two-way micromanipulator was used for accurate mapping of receptive fields. Diameters of G- and D-hair unit receptive fields were similar in both control and treated groups averaging 2.14 and 2.44 mm respectively with a 1.5 X threshold stimulus. It is concluded that the reported expansion of rat spinal cord cutaneous receptive fields following capsaicin treatment does not have any significant peripheral component.
D000818:Animals; D000831:Animals, Newborn; D002211:Capsaicin / Q000494:pharmacology*; D005260:Female; D006197:Hair; D008297:Male; D008465:Mechanoreceptors / Q000187:drug effects*; D009431:Neural Conduction; D051381:Rats; D012684:Sensory Thresholds
D002211:Capsaicin