[Effect of etatsizin on blood coagulability and the anticoagulant effect of heparin].
Etacyzine, a new antiarrhythmic drug of the phenothiazine series, injected intravenously (1 mg/kg) does not change the blood coagulation balance of rabbits. The effect of heparin (100 Units/kg i.v.) reduces after preinjection of etacyzine (1 mg/kg). Etacyzine lowers the concentration of heparin in an aqueous medium and blood plasma.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology*; D001777:Blood Coagulation / Q000187:drug effects*; D004347:Drug Interactions; D006493:Heparin / Q000494:pharmacology*; D010640:Phenothiazines / Q000494:pharmacology*; D011817:Rabbits; D013997:Time Factors
D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines; D006493:Heparin; C046818:ethacizine
Vliianie étatsizina na svertyvaemost' krovi i antikoaguliantnyĭ éffekt geparina.