[Antibacterial and antifungal compounds. V. Synthesis and antimicrobial activity of N-(2-arylethylaminophenyl)-1H-pyrryl-1-amine and 1-(1H-pyrrol-1-yl)-2-arylmethylbenzimidazole)].
The synthesis and antimicrobial activities of derivatives of 1-anilinopyrrole and 1-pyrrylbenzimidazole are described. The compounds here reported can be related to chlormidazole and other antifungal imidazole agents. The antifungal activity of the new derivatives tested proved lower than that of ketoconazole; some compounds were practically inactive.
D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D002175:Candida / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology
D000814:Aniline Compounds; D000935:Antifungal Agents; D001562:Benzimidazoles; D011758:Pyrroles
Ricerche su composti antibatterici ed antifungini. Nota V-Sintesi ed attività antimicrobica di N-(2-ariletilaminofenil)-1H-pirril-1-amine e di 1-(1H-pirrol-1-il)-2-arilmetilbenzimidazoli.