title: [Changes in systemic and pulmonary hemodynamics during an increase in lung volume].
abstract: 15 anesthetized dogs were subjected to a gradual increase of the lungs volume by means of administration of the 50% gas mixture of oxygen and air. The exceeding of the lungs volume by 600 ml increased pressure in the caudal vein, reduced blood flow and systolic pressure in the heart ventricles. After administration of 800 ml of the gas, the systolic pressure started to raise in the right ventricle and achieved 36.8 mm Hg at the moment of intrathoracic pressure of 21.5 mm H2O and cessation of the minor circulation. Then the right ventricle augmented its mechanic activity inducing tachycardia, raise of the pressure up to 45.2 mm Hg and restoration of the lung circulation.
mesh_terms: D000818:Animals; D004106:Dilatation; D004285:Dogs; D005260:Female; D006439:Hemodynamics; D008168:Lung / Q000294:innervation*; D008297:Male; D008465:Mechanoreceptors / Q000502:physiology*; D011652:Pulmonary Circulation
vernacular_title: Izmeneniia sistemnoĭ i legochnoĭ gemodinamiki pri uvelichenii ob"mena legkikh.