Ticlopidine as a hemorrhagic risk factor in coronary surgery.
We retrospectively reviewed the postoperative hemorrhagic risk in patients undergoing surgery for coronary revascularization who had received platelet antiaggregants preoperatively. A significant increase in postoperative hemorrhage and a higher percentage of reoperations for this reason was observed in the patients treated with ticlopidine. However, there were no major differences in the platelet counts among the groups compared.
D000328:Adult; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count; D011183:Postoperative Complications; D012189:Retrospective Studies; D012306:Risk; D013876:Thiophenes / Q000009:adverse effects*; D013988:Ticlopidine
D013876:Thiophenes; D013988:Ticlopidine