Hemodialysis of a dog with acute renal failure.
A dog with oliguric acute renal failure presumed to have been caused by ethylene glycol ingestion was treated by hemodialysis for 1 month. Hemodialysis was effective in controlling azotemia, hyperphosphatemia, and hyperkalemia when performed on a daily or alternate-day basis. The major complications during treatment were infection and severe weight loss. Serial renal biopsies disclosed a progression from initial acute tubular necrosis to severe diffuse interstitial fibrosis and mononuclear cell inflammation. Infection, cachexia, development of end-stage renal lesions, and terminal hyperkalemia contributed to the eventual death of the dog.
D058186:Acute Kidney Injury / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary*; D000818:Animals; D004283:Dog Diseases / Q000503:physiopathology / Q000628:therapy*; D004285:Dogs; D019855:Ethylene Glycol; D005026:Ethylene Glycols / Q000506:poisoning*; D008297:Male; D006435:Renal Dialysis / Q000662:veterinary*
D005026:Ethylene Glycols; D019855:Ethylene Glycol