title: The amino acid sequence of equine milk lysozyme.
abstract: The amino acid sequence of equine milk lysozyme has been elucidated. The study involves the determination of the sequence of the N-terminal region of the whole protein, cyanogen bromide fragments, tryptic and chymotryptic peptides and fragments produced by chemical cleavage after tryptophan residues. The protein consists of a single chain of 129 amino acid residues and has a Mr of 14647. While equine milk lysozyme has the essential features of a c(chick)-type lysozyme, there is only 51% sequence homology with human milk lysozyme and 50% with domestic hen egg white lysozyme. Some of the implications of the large number of differences are discussed.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001717:Birds / Q000378:metabolism; D005260:Female; D006736:Horses / Q000378:metabolism; D006801:Humans; D008322:Mammals / Q000378:metabolism; D008892:Milk / Q000201:enzymology*; D009113:Muramidase; D010063:Ovum / Q000201:enzymology; D013045:Species Specificity
chemical_list: D009113:Muramidase