title: Suckling decreases dopamine turnover in both medial and lateral aspects of the median eminence in the rat.
abstract: The effect of suckling on dopamine (DA) turnover was studied in the medial and lateral aspects of the median eminence. In 10-day postpartum lactating rats suckling decreased DA turnover 2.2-fold in the medial and 2.1-fold in the lateral median eminence. Norepinephrine turnover did not differ in suckled and non-suckled rats. These results are consistent with the hypothesis that decreased DA release is a component of the neuroendocrine reflex mediating suckling-induced prolactin release. The results further indicate that dopaminergic neurons distributing to both medial and lateral aspects of the median eminence are involved in the suckling response.
mesh_terms: D000818:Animals; D004298:Dopamine / Q000378:metabolism* / Q000502:physiology; D005260:Female; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D007774:Lactation; D008473:Median Eminence / Q000378:metabolism*; D008781:Methyltyrosines / Q000494:pharmacology; D009638:Norepinephrine / Q000378:metabolism; D011247:Pregnancy; D011388:Prolactin / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012018:Reflex / Q000502:physiology; D019805:alpha-Methyltyrosine
chemical_list: D008781:Methyltyrosines; D019805:alpha-Methyltyrosine; D011388:Prolactin; D004298:Dopamine; D009638:Norepinephrine