Effects of intra-amniotic isoxsuprine on amino acid placental transfer in rats.
Direct administration of isoxsuprine to the rat fetus increases placental transfer of 35S-methionine and this increase is statistically significant on day 17 as compared with intraperitoneal administration and controls (p less than 0.01; p less than 0.05). In contrast, no statistically significant differences were found between the groups on day 16.
D000596:Amino Acids / Q000378:metabolism*; D000650:Amnion; D000818:Animals; D005260:Female; D007267:Injections; D007556:Isoxsuprine / Q000008:administration & dosage / Q000494:pharmacology*; D008431:Maternal-Fetal Exchange / Q000187:drug effects*; D008715:Methionine / Q000378:metabolism; D010537:Peritoneum; D010920:Placenta / Q000187:drug effects*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
D000596:Amino Acids; D008715:Methionine; D007556:Isoxsuprine