[Antifibrillatory activity of anti-arrhythmia agents in maximally high ligation of the coronary artery and its reperfusion in cats].
Experiments on anesthesized cats were performed to study antifibrillatory action of the basic antiarrhythmic remedies and a new Soviet drug, phenicaberan. It was established that phenicaberan and lidocaine compare very favourably with other drugs under study as regards the antifibrillatory effect. For that reason these drugs can be recommended for use in the prophylaxis of fatal arrhythmias.
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001572:Benzofurans / Q000627:therapeutic use; D002415:Cats; D003331:Coronary Vessels; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D005260:Female; D008026:Ligation; D008297:Male; D009203:Myocardial Infarction / Q000150:complications; D014693:Ventricular Fibrillation / Q000517:prevention & control*
D000889:Anti-Arrhythmia Agents; D001572:Benzofurans; C015212:fenicoberan
Protivofibrilliatornaia aktivnost' nekotorykh antiaritmicheskikh sredstv pri maksimal'no vysokoĭ pereviazke koronarnoĭ arterii i ee reperfuzii u koshek.