Hepatitis B virus replication in acute glomerulonephritis with chronic active hepatitis.
A 3 year old boy who had chronic active hepatitis type B with features of ongoing liver damage and active virus replication, developed acute membranous glomerulonephritis two years after the clinical onset of liver disease, when both hepatitis B e antigen and antibody were detectable in serum. After withdrawal of short term steroid treatment and resolution of hepatitis B virus replication, both glomerulonephritis and chronic hepatitis went into remission. Some months later hepatitis B surface antigen was no longer found in serum.
D000208:Acute Disease; D000954:Antigens, Surface / Q000276:immunology; D002675:Child, Preschool; D005921:Glomerulonephritis / Q000150:complications / Q000382:microbiology*; D006509:Hepatitis B / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D006513:Hepatitis B e Antigens / Q000276:immunology; D006521:Hepatitis, Chronic / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D008297:Male; D014779:Virus Replication
D000954:Antigens, Surface; D006513:Hepatitis B e Antigens