[Morphological characteristics of changes in the skeletal muscle tissue of the extremities after experimental post-ischemic recirculation].
The canine ischemic muscle tissue was subjected to a comprehensive morphological study after the recovery of the blood flow in the limbs for 2 hours. The effectiveness of of the recovery of the blood flow after the 3-hour ischemia was supported in acute experimental occlusion of the artery. The blood flow recovery after 6 hours of ischemia was associated with appreciable structural and metabolic abnormalities in the skeletal muscle fibers. These abnormalities were more demonstrable during recirculation after 9 and 12 hours of ischemia. No morphological criteria that might indicate whether the ischemic damage to the skeletal muscle is reversible or irreversible were defined. A comprehensive morphological study with an assay of structural and metabolic alterations is required instead.
D000818:Animals; D004285:Dogs; D005121:Extremities / Q000098:blood supply*; D005260:Female; D007511:Ischemia / Q000473:pathology*; D008297:Male; D009132:Muscles / Q000098:blood supply* / Q000473:pathology / Q000502:physiology; D012038:Regeneration
Morfologicheskaia kharakteristika izmeneniĭ skeletnoĭ myshechnoĭ tkani konechnosteĭ pri éksperimental'noĭ postishemicheskoĭ retsirkulatsii.