[Hypersensitivity phenomena in dialysis patients. Incidence of eosinophilia, raised IgE and ethyleneoxide-induced antibodies].
The hypersensitivity parameters eosinophil count, serum IgE and IgE-type antibodies to ethylene oxide-albumin conjugates (ETO-antibodies), were determined in 182 dialysis patients. Eosinophilia was seen in 21.7% of patients, IgE elevation in 21.4% and ETO-antibodies in 12.4%. A pathological change in at least one of the measured parameters was present in 33.1%. The appearance of ETO-antibodies was frequently associated with severe clinical symptoms, especially asthma and anaphylactic shock. Sensitisation is apparently common in dialysis patients. Since ETO-antibodies are often associated with severe clinical symptoms, their presence should be sought in those dialysis patients showing incompatibility reactions or asthma.
D000328:Adult; D000906:Antibodies / Q000032:analysis*; D001249:Asthma / Q000209:etiology; D004802:Eosinophilia / Q000209:etiology*; D005027:Ethylene Oxide / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*
D000906:Antibodies; D007073:Immunoglobulin E; D005027:Ethylene Oxide
Hypersensitivitätsphänomene bei Dialysepatienten. Häufigkeit von Eosinophilie, IgE-Erhöhung und Ethylenoxid-induzierten Antikörpern.