Autoradiographic demonstration of deoxyglucose uptake in guinea pig cochlea.
The 2-deoxyglucose autoradiographic method was applied to whole-body cryosectioning to include the cochlea. The highest levels of 2-deoxyglucose uptake were observed in the vascular stria, spiral ligament and spiral prominence. The cochlear nerve showed the next highest level of uptake, while the organ of Corti and the spiral ganglion showed low levels. The functional significance of the results was briefly discussed.
D000818:Animals; D001345:Autoradiography; D001786:Blood Glucose / Q000378:metabolism*; D003051:Cochlea / Q000378:metabolism*; D003053:Cochlear Duct / Q000378:metabolism; D003847:Deoxyglucose / Q000378:metabolism; D006168:Guinea Pigs; D009925:Organ of Corti / Q000378:metabolism; D013136:Spiral Ganglion / Q000378:metabolism; D013137:Spiral Lamina / Q000378:metabolism; D013316:Stria Vascularis / Q000378:metabolism
D001786:Blood Glucose; D003847:Deoxyglucose