[Effect of irradiation and chemical differentiation inducers on the survival of thymus lymphocytes in mice].
Chemical inductors of differentiation were shown to produce a cytotoxic effect on thymus cells. The protein synthesis inhibitors prevented this effect. The toxic action of the inductors was more pronounced in a most radiosensitive thymocyte fraction. A combination of differentiation inductors and ionizing radiation did not produce the additive effect. This was observed after the effect of radiation and substances being not the differentiation inductors but toxic for cells.
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D002478:Cells, Cultured; D005720:Gamma Rays; D008214:Lymphocytes / Q000187:drug effects / Q000528:radiation effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects*; D013997:Time Factors
Vliianie oblucheniia i khimicheskikh induktorov differentsirovki na vyzhivaemost' limfotsitov timusa mysheĭ.