title: Weill-Marchesani syndrome with bilateral angle-closure glaucoma.
abstract: To our knowledge this is the first reported case of cyclopentolate induced bilateral acute angle-closure glaucoma associated with the Weill-Marchesani syndrome without lens subluxation. The diagnosis of Weill-Marchesani syndrome was not initially suspected, and Pilocarpine was used in an attempt to break the acute attack. Treatment with Pilocarpine-induced myosis only worsened the glaucoma by causing a severe pupillary block. This case is important because it demonstrates that mid-dilatation and cycloplegia can induce acute glaucoma in patients with the Weill-Marchesani syndrome and points out the importance for considering the diagnosis of Weill-Marchesani syndrome in any case of acute glaucoma in childhood.
mesh_terms: D000015:Abnormalities, Multiple / Q000150:complications* / Q000188:drug therapy; D001824:Body Constitution; D002648:Child; D005128:Eye Diseases / Q000150:complications*; D005385:Fingers / Q000002:abnormalities*; D005901:Glaucoma / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006801:Humans; D007596:Joints / Q000002:abnormalities*; D008297:Male; D008663:Metacarpus / Q000002:abnormalities*; D010862:Pilocarpine / Q000009:adverse effects / Q000627:therapeutic use; D012886:Skull / Q000002:abnormalities*; D013577:Syndrome
chemical_list: D010862:Pilocarpine