17/7 translocation trisomy: practical vindication of a model of sickness.
A girl was seen by a psychiatrist for relentless rubbing of her eyes and difficult behaviour. A proper diagnosis of her sickness required an understanding of the cause of her physical stigmata, which disclosed a previously undescribed chromosome anomaly (partial trisomy 17p); her mental handicap and behavioural disorder, which were partly a function of parental despair; and the predicament of her father and other carrier relatives who were identified through this child. Explanation or alteration of each component of sickness was necessary to achieve beneficial change.
D002653:Child Behavior Disorders / Q000235:genetics* / Q000628:therapy; D002675:Child, Preschool; D002869:Chromosome Aberrations / Q000523:psychology; D025063:Chromosome Disorders; D002902:Chromosomes, Human, 16-18; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D010375:Pedigree; D012652:Self Mutilation / Q000517:prevention & control; D014178:Translocation, Genetic; D014314:Trisomy