title: [LDL-apheresis in the treatment of familial hypercholesterolemia].
abstract: Several non-pharmacological treatments have been tested for homozygous familial hypercholesterolemia and, among these, plasma-exchange has been the most safe and effective. A recent development of this procedure is LDL-apheresis, that is the selective removal of atherogenic LDL and the return to the patient of his own LDL-depleted plasma. The method is based on the flowing of hypercholesterolemic plasma on sepharose columns with bound anti-LDL antibodies.
mesh_terms: D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000628:therapy*; D008077:Lipoproteins, LDL / Q000097:blood*; D008722:Methods; D010956:Plasmapheresis
chemical_list: D008077:Lipoproteins, LDL
vernacular_title: LDL-aferesi nel trattamento dell'ipercolesterolemia familiare.