title: Adrenomyeloneuropathy: report of a family and electron microscopical findings in peripheral nerve.
abstract: A family with adrenomyeloneuropathy (AMN) is reported, whose female carriers showed severe neurological and biochemical abnormalities. Cytoplasmic lamellar inclusions were found in endoneurial cells of the biopsied sural nerve of a male patient. In spite of the peripheral nervous system involvement in patients with AMN, there have been few reports of these inclusions in the peripheral nerves of such cases.
mesh_terms: D000307:Adrenal Gland Diseases / Q000235:genetics* / Q000473:pathology; D000328:Adult; D000368:Aged; D001706:Biopsy; D002353:Carrier State; D003711:Demyelinating Diseases / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009128:Muscle Spasticity / Q000235:genetics* / Q000473:pathology; D010243:Paralysis / Q000235:genetics* / Q000473:pathology; D010375:Pedigree; D013127:Spinal Nerves / Q000473:pathology*; D013497:Sural Nerve / Q000473:pathology*