Dark- and light-adapted visual evoked cortical potentials in retinitis pigmentosa.
Fifty patients with all genetic types of retinitis pigmentosa (RP) were tested with the visually evoked cortical potential (VECP) by full-field flashes of blue and red light in the dark-adapted state and white light flashes in the light-adapted state. VECPs were recorded in all but one of these patients, even those with only a few degrees of central visual field remaining. In a subgroup of patients the absence of the VECP to blue light, dark-adapted, was correlated with a final dark-adapted threshold at or above cone threshold. These observations suggest that the VECP may be a useful objective method of assessment of patients with RP especially patients without detectable ERGs.
D000222:Adaptation, Physiological; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003623:Dark Adaptation; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D008027:Light; D008297:Male; D008875:Middle Aged; D012174:Retinitis Pigmentosa / Q000503:physiopathology*; D014793:Visual Cortex / Q000503:physiopathology*