[Role of limbic-neocortical mechanisms in the formation of experimental alcoholism in the rat].
The role of the amigdalar complex and the hippocampus as well as their interaction with the hypothalamus in a formation of attraction to alcohol was studied in 40 rats. After electrolytic lesions of the hippocampus and the amigdalar complex at early stages of alcoholization the inhibition of development of this pathologic attraction occurred however with subsequent dynamical reorganization of the structural and functional mechanisms of alcoholic motivation and with duplication of the triggering links. Important role of the limbico-neocortical relations was revealed in a development of behavioural and emotional-vegetative disturbances accompanying experimental alcoholism.
D000437:Alcoholism / Q000209:etiology / Q000503:physiopathology*; D000679:Amygdala / Q000503:physiopathology; D000818:Animals; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology*; D004569:Electroencephalography; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D008032:Limbic System / Q000503:physiopathology*; D008297:Male; D051381:Rats; D012653:Self Stimulation / Q000502:physiology; D013997:Time Factors
Rol'limbiko-neokortikal'nykh mekhanizmov v formirovanii éksperimental'nogo alkogolizma u krys.