Safety and efficacy of clavulanate-potentiated amoxycillin in pigeons (Columba livia).
Pigeons treated orally with 125 mg clavulanate-potentiated amoxycillin for seven days showed no adverse reactions. The drug had a marked depressive effect on the faecal flora but this had returned to normal 10 days after cessation of treatment. When administered to pigeons with an experimental Staphylococcus aureus infection of the feet no clinical response was apparent and there was no evidence of a diminution in the inflammatory process.
D000658:Amoxicillin / Q000494:pharmacology* / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects*; D001715:Bird Diseases / Q000188:drug therapy*; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000494:pharmacology* / Q000627:therapeutic use; D010856:Columbidae / Q000382:microbiology*; D004195:Disease Models, Animal; D004357:Drug Synergism; D005243:Feces / Q000382:microbiology; D005534:Foot Diseases / Q000188:drug therapy / Q000662:veterinary*; D012449:Safety; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000662:veterinary*
D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D019818:Clavulanic Acid; D000658:Amoxicillin