title: [Changes in the number of Ec cells in the small intestine and the serotonin level in the blood plasma of fasting rats].
abstract: A study was made of the amount of Ec-cells in the small intestine mucosa and blood plasma serotonin of rats in health and fasting. It was established that 24 hours after food deprivation the amount of Ec-cells rises approximately 2-fold as compared with control. The cells demonstrate the intensification of the argentaffin reaction. The content of serotonin in blood plasma increases 2-fold accordingly. On day 3 of fasting the amount of Ec-cells and intensity of the argentaffin reaction decrease to normal, whereas the content of blood plasma serotonin does not change essentially. This may be linked with a massive release of serotonin to blood and depletion of Ec-cells because of which the threshold of their histochemical demonstration is reduced. On day 7 of food deprivation the amount of Ec-cells and the intensity of the argentaffin reaction increase again but the serotonin content dramatically falls down. This phenomenon may be related to the derangement of serotonin release to blood or to the transformation from the synthesis of serotonin to the synthesis of some other hormone, most likely melatonin.
mesh_terms: D000818:Animals; D002452:Cell Count; D002838:Chromaffin System / Q000473:pathology*; D004759:Enterochromaffin Cells / Q000473:pathology*; D005215:Fasting; D007413:Intestinal Mucosa / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology*; D051381:Rats; D012701:Serotonin / Q000097:blood*; D013997:Time Factors
chemical_list: D012701:Serotonin
vernacular_title: Izmeneniia kolichestva Ec-kletok v tonkoĭ kishke i urovnia serotonina v plazme krovi krys pri golodanii.