Relapsing acute pancreatitis as the presenting manifestation of an ampullary neoplasm in a patient with familial polyposis coli.
The incidence of periampullary carcinoma is increased in patients with familial polyposis coli or the Gardner syndrome. Patients with familial polyposis coli and ampullary tumors usually present with obstructive jaundice or abdominal pain. We report the case of a 41-year-old woman with the Gardner syndrome in whom relapsing acute pancreatitis was the presenting manifestation of an ampullary neoplasm. A diagnosis of ampullary neoplasm should be considered in any patient with familial polyposis coli or the Gardner syndrome and pancreatitis, even in cases of relapsing acute pancreatitis.
D000208:Acute Disease; D000328:Adult; D014670:Ampulla of Vater / Q000000981:diagnostic imaging; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003111:Colonic Polyps / Q000150:complications / Q000235:genetics*; D003138:Common Bile Duct Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D005736:Gardner Syndrome / Q000150:complications*; D006801:Humans; D010195:Pancreatitis / Q000209:etiology*; D012008:Recurrence