Studies on microcapsules to replace erythrocytes in the passive agglutination reaction.
Two kinds of microcapsules were made from polyurethane and polyurea. Each capsule had a mean diameter of 6 microns, a specific gravity of 1.10, and was red in color. The capsules were coated with ovalbumin condensed with glutaraldehyde. The coated capsules were agglutinated with anti-ovalbumin antibody. The polyurethane capsule (positive charge) bound more ovalbumin and showed a higher sensitivity than did the polyurea capsule (negative charge) or erythrocytes.
D000372:Agglutination Tests / Q000379:methods*; D000818:Animals; D002214:Capsules; D004912:Erythrocytes / Q000276:immunology; D006386:Hemagglutination Tests; D010047:Ovalbumin / Q000276:immunology; D011108:Polymers; D011140:Polyurethanes; D011817:Rabbits; D051381:Rats
D002214:Capsules; D011108:Polymers; D011140:Polyurethanes; C045786:polyurea; D010047:Ovalbumin