Combined therapy of malignant stenoses of the upper gastrointestinal tract by means of laser beam and bougienage.
Eighteen patients with malignant inoperable stenoses of the upper digestive tract were treated with a combination of laser (neodymium-YAG) coagulation and bougienage. Following treatment, 14 out of 18 patients (78%) were able to eat solid food again; the width of the lumen was greater than 11 mm in every case. Between 1 and 5 laser sessions (median 3.5) and between 1 and 2 (median 1) bougienages were required; per session, between 1,017 and 9,096 joules (median 3,362) were required, and a total of between 4,770 and 36,244 joules (median 8,763) were utilized per patient treated. To date, 6 patients remain free of dysphagia (at between 3 and 24 weeks), 1 patient has in the meantime been submitted to surgery. In 7 patients, recurrent stenosis occurred, which was again treated with the laser (3) or with an endoscopically implanted prosthetic tube (4). In 4 patients, the result was unsatisfactory. By way of major complications, merely one perforation occurred. We conclude that the combined use of laser coagulation and bougienage represents an effective and largely complication-free palliative treatment for malignant stenoses in the upper digestive tract.
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000150:complications; D004940:Esophageal Stenosis / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D004945:Esophagoscopy; D005260:Female; D005773:Gastroscopy; D006801:Humans; D053685:Laser Therapy; D007834:Lasers; D008297:Male; D008875:Middle Aged; D013272:Stomach Diseases / Q000150:complications / Q000601:surgery / Q000628:therapy*; D013274:Stomach Neoplasms / Q000150:complications