title: Paracentric inversions in man.
abstract: Two new cases of familial paracentric inversions, 46,XY,inv(3)(p21.1p25) and 46,XY,inv(7) (q22.3q36.1) are presented. A review of published cases suggests that prenatal diagnosis for carriers of paracentric inversions is not warranted. However, care must be exercised in eliminating the possibility of insertions.
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics; D000022:Abortion, Spontaneous / Q000235:genetics; D000328:Adult; D007446:Chromosome Inversion; D002900:Chromosomes, Human, 1-3; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy