Early radiation-induced proctosigmoiditis responds to magnesium therapy.
A group of 10 patients with cervical carcinoma with early radiation-induced proctosigmoiditis and low serum Mg levels was treated with low residue diet and antidiarrheals. The diarrhea cleared within a period of 2-6 weeks. A second group of 10 patients with hypomagnesemia was treated with intravenous infusion of Mg sulfate for 3 consecutive days. The diarrhea disappeared by the end of treatment, paralleling normalization of serum Mg levels.
D003092:Colitis / Q000188:drug therapy*; D003967:Diarrhea / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use*; D011350:Proctocolitis / Q000188:drug therapy* / Q000209:etiology; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000532:radiotherapy*
D008274:Magnesium