title: Schistosoma mansoni: an ultrastructural examination of skin migration in the hamster cheek pouch.
abstract: The hamster cheek pouch has been used to investigate the skin migration of schistosomula at the ultrastructural level. Parasites have been observed up to 72 h post-infection. Despite rapidly reaching the epidermal basement membrane schistosomula remain in an epidermal location for at least 40 h post-infection, by which time the acetabular glands and their ducts have been lost and the transformation from cercaria to schistosomulum completed. Entry into the dermis and exit from the skin via the blood vessels is therefore by mechanical means or by lytic secretions emanating from a source other than the acetabular glands. The head gland which persists in the dermal schistosomula is a probable source of such secretions. The observations suggest that the apical area and musculature of the head capsule are important in gaining access to the lumen of blood vessels.
mesh_terms: D000818:Animals; D002610:Cheek / Q000469:parasitology; D006224:Cricetinae; D003412:Cricetulus; D004817:Epidermis / Q000469:parasitology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009061:Mouth Mucosa / Q000469:parasitology* / Q000648:ultrastructure; D009068:Movement; D012550:Schistosoma mansoni / Q000254:growth & development / Q000502:physiology / Q000648:ultrastructure*; D012552:Schistosomiasis / Q000469:parasitology*; D012867:Skin / Q000469:parasitology*