Subarachnoid haemorrhage in the rat: angiography and fluorescence microscopy of the major cerebral arteries.
A subarachnoid haemorrhage (SAH) in the rat was produced by the injection of blood via a previously implanted catheter connected to the cisterna magna. Repeated angiographical examinations of the vertebro-basilar arteries revealed a biphasic vasospasm with a maximal acute spasm at ten minutes and a maximal late spasm at two days after cisternal blood injection. Fluorescence microscopical examination of the major cerebral arteries at day two after the SAH revealed a reduction in the fluorescence intensity and in the number of histochemically visible sympathetic nerve terminals.
D000818:Animals; D001488:Basilar Artery / Q000473:pathology; D002339:Carotid Arteries / Q000473:pathology; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000473:pathology*; D002946:Cisterna Magna / Q000473:pathology; D004195:Disease Models, Animal; D008856:Microscopy, Fluorescence; D051381:Rats; D011919:Rats, Inbred Strains; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis*; D014135:Tracheal Stenosis / Q000401:mortality; D014711:Vertebral Artery / Q000473:pathology