title: Clear cell variant of medullary carcinoma of the thyroid.
abstract: A previously unreported clear cell variant of medullary thyroid carcinoma is described. This histologic appearance was observed in sections from both the primary thyroid tumor and a vertebral metastasis. This variant merits recognition because it may be confused with a variety of other tumors occurring in the thyroid that contain cells with optically clear cytoplasm. Immunohistochemical and ultrastructural studies can be helpful in establishing the diagnosis of these tumors.
mesh_terms: D000328:Adult; D002116:Calcitonin / Q000378:metabolism; D002277:Carcinoma / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D013964:Thyroid Neoplasms / Q000378:metabolism / Q000473:pathology*
chemical_list: D002116:Calcitonin