[Conformation of glycopeptides with L- and D-stereoisomers of Ala and Glu amino acids].
On the base of the semi-empirical method of conformational analysis low-energetic conformations have been found for the glycopeptides with the O-beta-N-acetyl-D-muramic acid or the O-beta-N-acetyl--D-glucosaminyl-(1-4)-N-acetyl-D-muramic acid in the glycan part and L-Ala--D-GluNH2, L-Ala--L-GluNH2, D-Ala--D-GluNH2 in the peptide part. It was shown that for either molecule preferentiability of any conformation is determined mainly by interactions between dipeptide and muramic acid residue.
D000409:Alanine; D002236:Carbohydrate Conformation; D005973:Glutamine; D006020:Glycopeptides; D008958:Models, Molecular; D011487:Protein Conformation; D013237:Stereoisomerism
D006020:Glycopeptides; D005973:Glutamine; D000409:Alanine
Konformatsiia glikopeptidov s L- i D-stereoisomerami aminokislot Ala i Glu.