title: The pattern of cortical projections from the intermediate parts of the magnocellular nucleus basalis in the rat demonstrated by tracing with Phaseolus vulgaris-leucoagglutinin.
abstract: The pattern and distribution of the cortical projections from intermediate parts of the cholinergic basal magnocellular nucleus were studied by anterogradely transported Phaseolus vulgaris-leucoagglutinin. This immunocytochemical tracing technique reveals the detailed morphology and distribution of efferents from this intermediate area in the nucleus basalis to the various areas and layers of cortex and amygdala. Major projections with a relatively high density of terminal boutons were found in layers I, II and VI of the frontal cortex, in layers V and VI of parietal and temporal areas, in the entire perirhinal and entorhinal cortices, and in the basolateral nucleus of the amygdaloid body. From the nucleus basalis area studied, few if any projections could be demonstrated to cingulate and occipital cortical regions.
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000344:Afferent Pathways / Q000033:anatomy & histology; D000679:Amygdala / Q000033:anatomy & histology; D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology*; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D002799:Cholinergic Fibers; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013377:Substantia Innominata / Q000033:anatomy & histology* / Q000201:enzymology
chemical_list: D002795:Choline O-Acetyltransferase; D000110:Acetylcholinesterase