title: Comparison of non-histone proteins from hamster Kirkman-Robbins hepatoma and liver.
abstract: Three classes of non-histone proteins were obtained from hamster Kirkman-Robbins hepatoma and liver nuclei following separation of nucleic acids with the polyethylene glycol-dextran mixture and fractionation of nuclear proteins on hydroxylapatite in a salt-glycerol-phenylmethylsulphonyl fluoride system at increasing concentrations of Na+ and K+ phosphate buffer, pH 6.8. Two-dimensional polyacrylamide gel electrophoresis of these proteins documented their high heterogeneity; many spots were common but some spots specific only for neoplastic or normal tissue were also observed.
mesh_terms: D000818:Animals; D002868:Chromosomal Proteins, Non-Histone / Q000032:analysis*; D006224:Cricetinae; D007526:Isoelectric Point; D008099:Liver / Q000032:analysis*; D008114:Liver Neoplasms, Experimental / Q000032:analysis*; D008970:Molecular Weight
chemical_list: D002868:Chromosomal Proteins, Non-Histone