title: Continuous ambulatory venous pressure for diagnosis of venous insufficiency. Preliminary report.
abstract: We have found that the venous pressure slope during minimal exercise is a sensitive measurement of venous disease. This parameter differed greatly in our two study populations. Due to increased venous pressure, venous insufficiency syndrome patients have a greater volume of pooled blood, which results in smaller pressure changes with each muscle contraction. In patients with incompetent valves, blood flows in a retrograde fashion in the vein, which leads to a higher steady state minimal pressure and notably to a decreased venous pressure slope. Venous pressure slope is a particularly sensitive measurement and a good prognosticator of venous insufficiency syndrome before symptoms become disabling to the patient. Our data indicate a strong correlation between venous pressure slope and venographic results. In fact, patients with abnormal venographic results invariably have demonstrated venous pressure slopes in the abnormal range.
mesh_terms: D000553:Ambulatory Care; D001795:Blood Pressure Determination / Q000379:methods*; D005080:Exercise Test; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008991:Monitoring, Physiologic / Q000379:methods; D010690:Phlebography; D011187:Posture; D014689:Venous Insufficiency / Q000503:physiopathology*; D014690:Venous Pressure