Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought.
Reversible chronic cerebellar ataxia followed phenytoin treatment in two epileptic women. Cerebellar ataxia in both patients and axonal polyneuropathy in one patient were improved after administration of thiamine alone or with folate. In one patient, some specific behavioral functions improved. However, recovery could have been spontaneous.
D000293:Adolescent; D002524:Cerebellar Ataxia / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D002531:Cerebellum / Q000502:physiology*; D002908:Chronic Disease; D003071:Cognition / Q000502:physiology*; D004569:Electroencephalography; D004576:Electromyography; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009431:Neural Conduction; D009483:Neuropsychological Tests; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D010672:Phenytoin