Alternations of Clonorchis sinensis EPG by administration of herbs in rabbits.
In order to investigate clonorchicidal activity in vivo, boiled water extracts of 32 species of clonorchicidal raw drugs in vitro were orally administered into rabbits infected with Clonorchis sinensis. The results of the observation of EPG variation were as follows: Suppression effects of egg-laying capacity from the rabbits administered Prunus mume and Inula helenium were greatest. Those from Dictamnus dasycarpus and Saussurea lappa were somewhat effective. Machilus thunbergii and Cassia obutusifolia, however, were less effective.
D000818:Animals; D000871:Anthelmintics / Q000302:isolation & purification / Q000627:therapeutic use*; D002681:China; D003003:Clonorchiasis / Q000188:drug therapy* / Q000469:parasitology; D004353:Drug Evaluation, Preclinical; D005243:Feces / Q000469:parasitology; D010270:Parasite Egg Count; D010946:Plants, Medicinal; D011817:Rabbits
D000871:Anthelmintics