Inhibitory effect of 17-beta-estradiol on the activity of liver alanine aminotransferase in adult female rats.
The inhibitory effect of daily s.c. administration of cca 50 micrograms kg-1 17-beta-estradiol on liver alanine aminotransferase activity of adult female rats, the absence of this effect after bilateral adrenalectomy and its reappearance after gluccorticoid substitution is described.
D000315:Adrenalectomy; D000410:Alanine Transaminase / Q000378:metabolism*; D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains
D004958:Estradiol; D003907:Dexamethasone; D000410:Alanine Transaminase