title: Doxycycline in human oviduct mucosa and plasma 24-30 hours after an oral dose of 100 mg.
abstract: Oviductal and peripheral plasma concentrations 24 hours after the last dose of Doxycycline (DC) were studied in 17 patients. The concentration of DC in healthy oviduct mucosa was 1.3 micrograms/g (range 0.6-1.7) and 1.1 micrograms/ml (range 0.6-1.7) in plasma. One patient with severe chronic salpingitis in acute exacerbation showed 3.6 micrograms/g in tissue and 2.4 micrograms/ml in plasma in proliferative phase.
mesh_terms: D000328:Adult; D000368:Aged; D004318:Doxycycline / Q000008:administration & dosage / Q000378:metabolism*; D005187:Fallopian Tubes / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009092:Mucous Membrane / Q000378:metabolism; D012488:Salpingitis / Q000188:drug therapy; D013997:Time Factors
chemical_list: D004318:Doxycycline