title: [Preliminary open multicenter study on the anti-tremorigenic effectiveness of bornaprine (Sormodren)].
abstract: Out of 1500 patients suffering from tremor of diverse origin, reliable data on 521 were selected for analysis. The drug was given for over two months (mean daily dose 8 mg) and effectively reduced all kinds of tremor by an average 50%. The only side-effects occurring with any frequency were dryness of the mouth and constipation. The data collected show bornaprine to have a beneficial effect on all types of tremor.
mesh_terms: D000368:Aged; D001952:Bridged-Ring Compounds / Q000009:adverse effects / Q000627:therapeutic use*; D003248:Constipation / Q000139:chemically induced; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy; D014202:Tremor / Q000145:classification / Q000188:drug therapy*; D014987:Xerostomia / Q000139:chemically induced
chemical_list: D001952:Bridged-Ring Compounds; C006088:bornaprine
vernacular_title: Studio preliminare multicentrico "in aperto" sulla efficacia antitremorigena del bornaprine (Sormodren).