title: [Operative indications and surgical procedure in iodine-induced hyperthyroidism].
abstract: Clinical course, indications for surgical treatment, and results of treatment in 8 female patients with iodine induced thyrotoxicosis (IIT) are reported. The diagnosis of IIT could be established in all patients by a) clinical hyperthyroidism, b) increased T3 and T4 serum concentrations, and c) previous iodine contamination. Sources of iodine were radiographic contrast agents for urography (n = 4), oral cholecystography (n = 3), intravenous cholangiography (n = 1), phlebography (n = 1), and cranial computer tomography (n = 1). The onset of hyperthyroidism occurred 1-8 weeks after iodine exposure. Indications for surgical treatment of IIT were: 1. autonomous nodular goiter (n = 6), and 2. iodine exacerbation of preexisting thyrotoxicosis in patients with Graves' disease (n = 2). Corresponding to the different pathogenesis of autonomous and immunogenetic goiter the following surgical treatment is recommended: Enucleation of solitary autonomous adenomas or unilateral lobectomy in case of large adenomas, subtotal bilateral lobectomy in toxic multinodular goiter or, preferentially, unilateral lobectomy combined with subtotal resection of the contralateral thyroid lobe; "Near-total" thyroidectomy in Graves' immunopathy.
mesh_terms: D000328:Adult; D003287:Contrast Media / Q000009:adverse effects*; D005260:Female; D006044:Goiter, Nodular / Q000139:chemically induced / Q000601:surgery; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced* / Q000601:surgery; D007455:Iodine / Q000009:adverse effects*; D008875:Middle Aged; D013965:Thyroidectomy; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D003287:Contrast Media; D014284:Triiodothyronine; D007455:Iodine; D013974:Thyroxine
vernacular_title: Operationsindikation und chirurgisches Vorgehen bei jodinduzierten Hyperthyreosen.