title: [Criteria for the activity of the pathologic process in multiple sclerosis (clinico-computer tomographic correlations)].
abstract: Eight patients with the clinical signs of disease exacerbation were examined using computer-aided tomography of the head with contrast intensification. In 4 patients with a clinical aggravation expressed in the appearance of new neurological symptoms the authors obtained an effect of contrast intensification. Routine examination of the zones of the white substance revealed drug accumulation in the zones of both subnormal and normal density. There was no drug cumulation in 4 patients whose clinical aggravation was connected with the previous neurological symptomatology. The data obtained are discussed.
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000494:pharmacology; D000328:Adult; D001812:Blood-Brain Barrier / Q000187:drug effects; D001921:Brain / Q000000981:diagnostic imaging*; D003974:Diatrizoate Meglumine; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000305:Adrenal Cortex Hormones; D003974:Diatrizoate Meglumine
vernacular_title: O kriteriiakh aktivnosti patologicheskogo protsessa pri rasseiannom skleroze (kliniko-komp'iuterno-tomograficheskie sopostavleniia).