A quantitative electron microscope study of the perikaryal projections of sensory ganglion neurons. II. Gecko and lizard.
The perikaryal projections of the neurons in the thoracic spinal ganglia of gecko and lizard usually appear as finger-shaped evaginations running roughly parallel to the surface of the nerve cell body; they show a nearly circular cross section with a rather uniform transverse diameter having an average value of about 0.2 micron. In both gecko and lizard a very high correlation was found between the surface area of perikaryal projections and both the volume and smoothed surface area of the corresponding nerve cell body. The results of the present research agree with those obtained in a previous study on two mammal species (cat and rabbit) and lend further support to the hypothesis advanced in that study; i.e., that perikaryal projections in sensory ganglion neurons are normal formations which maintain the surface-to-volume ratio above the critical level for metabolic exchanges. Perikaryal projections increase the surface area of the nerve cell body by 32.5% in gecko and 30% in lizard, while they increase it by 43% in cat and 39.5% in rabbit. This difference may be related to the lower metabolic rate of the neurons in poikilotherms than in mammals.
D000818:Animals; D002415:Cats; D002462:Cell Membrane / Q000648:ultrastructure*; D005727:Ganglia, Spinal / Q000166:cytology*; D008116:Lizards / Q000033:anatomy & histology*; D008854:Microscopy, Electron; D009474:Neurons / Q000648:ultrastructure*; D011817:Rabbits