title: Evidence that the first step leading to carcinogen-induced malignant transformation is a high frequency, common event.
mesh_terms: D000818:Animals; D002273:Carcinogens; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000187:drug effects* / Q000473:pathology; D004260:DNA Repair; D051379:Mice
chemical_list: D002273:Carcinogens