title: [Long-term study of women with biopsy-proven mastopathy].
abstract: Out of a total of 1306 women (average age 42 years) with a biopsy proven mastopathy, manifest ipsilateral carcinoma occurred in 13 during the following 6 years. Thus the incidence of carcinoma differed little from the expected number of new cases in women of a comparable age. However, subdivision of breast lesions into simple (n = 1052) and proliferative (n = 254) forms showed that the carcinoma risk is double in proliferative mastopathy and fourfold higher when mastopathy with atypical epithelial proliferation is considered. An association with contraceptive hormones was not seen.
mesh_terms: D000328:Adult; D001706:Biopsy; D001941:Breast Diseases / Q000145:classification / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D001943:Breast Neoplasms / Q000209:etiology* / Q000601:surgery; D003278:Contraceptives, Oral, Hormonal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D012306:Risk
chemical_list: D003278:Contraceptives, Oral, Hormonal
vernacular_title: Langzeitbeobachtung von Frauen mit bioptisch gesicherter Mastopathie.