title: Electron microscopic study of water-insoluble fractions in normal and cataractous human lens fibers.
abstract: Water-insoluble fractions of fiber cells from human transparent normal and opacified single lenses were compared ultrastructurally and by gel electrophoresis. Intermediate-sized filaments which had been clearly shown in aged transparent normal cortices, virtually vanished in the opacified nuclei in contrast to microfilaments.
mesh_terms: D008841:Actin Cytoskeleton / Q000648:ultrastructure; D000199:Actins / Q000032:analysis; D000328:Adult; D000368:Aged; D002386:Cataract / Q000473:pathology*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007382:Intermediate Filaments / Q000648:ultrastructure; D007904:Lens Cortex, Crystalline / Q000032:analysis; D007908:Lens, Crystalline / Q000648:ultrastructure*; D008854:Microscopy, Electron; D008875:Middle Aged; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014746:Vimentin