Switching monoamine oxidase inhibitors.
Substituting one monoamine oxidase inhibitor for another is recommended only after a drug-free interval to avoid hypertensive emergencies. The evidence and mechanism firmly supporting this caution is lacking. We report a case where monoamine oxidase inhibitors were substituted without apparent adverse consequences.
D000328:Adult; D003866:Depressive Disorder / Q000188:drug therapy; D006801:Humans; D008094:Lithium / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D010624:Phenelzine / Q000009:adverse effects* / Q000627:therapeutic use; D014191:Tranylcypromine / Q000009:adverse effects / Q000627:therapeutic use
D008996:Monoamine Oxidase Inhibitors; D014191:Tranylcypromine; D008094:Lithium; D010624:Phenelzine