title: Paracrine regulation of lung maturation.
abstract: Although there is much yet to be learned about the regulation of fetal lung maturation, the study of this process has yielded much information that may serve as a paradigm for the understanding of fetal growth regulation in general. Two particularly interesting fetal adjustments of general regulatory phenomena have emerged: the ability of local tissue metabolism to anatomically or temporally isolate endocrine effects and the role of paracrine factors in coordinating the responses of different cells in complex organs.
mesh_terms: D000818:Animals; D002450:Cell Communication; D003348:Cortisone / Q000378:metabolism; D004847:Epithelial Cells; D005325:Fetal Organ Maturity; D005346:Fibroblast Growth Factors / Q000502:physiology; D005938:Glucocorticoids / Q000378:metabolism; D006854:Hydrocortisone / Q000378:metabolism; D008168:Lung / Q000196:embryology* / Q000378:metabolism; D009490:Neurosecretory Systems / Q000196:embryology*; D011817:Rabbits; D051381:Rats
chemical_list: D005938:Glucocorticoids; C044220:fibroblast pneumonocyte factor; D005346:Fibroblast Growth Factors; D003348:Cortisone; D006854:Hydrocortisone