Vascular permeability in experimental spinal cord injury.
Following spinal cord injury in rats there was a time-dependent change of vascular permeability as reflected by extravasation of 125I-labelled serum albumin. The change of vascular permeability correlated with tissue calcium and water accumulation suggesting that cord exposure to plasma calcium as a consequence of vascular injury may contribute to the progressive post-traumatic cord necrosis.
D000818:Animals; D002118:Calcium / Q000032:analysis; D002199:Capillary Permeability; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012709:Serum Albumin / Q000378:metabolism; D013116:Spinal Cord / Q000032:analysis / Q000098:blood supply*; D013119:Spinal Cord Injuries / Q000503:physiopathology*; D014867:Water / Q000032:analysis
D012709:Serum Albumin; D014867:Water; D002118:Calcium