Nasal carriage of Staphylococcus aureus and antistaphylococcal immunoglobulin E antibodies in atopic dermatitis.
Twelve atopic dermatitis patients were studied to investigate the relationship between levels of antistaphylococcal immunoglobulin E antibodies in serum and quantitative cultures of Staphylococcus aureus strains from the anterior nares and chronic lesions. A positive correlation was found between logarithmic counts of S. aureus strains from the anterior nares and levels of antistaphylococcal immunoglobulin E in serum. The observation is important for understanding the pathophysiology of atopic dermatitis.
D000293:Adolescent; D000907:Antibodies, Bacterial / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007223:Infant; D009666:Nose / Q000382:microbiology*; D012867:Skin / Q000382:microbiology; D013211:Staphylococcus aureus / Q000254:growth & development* / Q000276:immunology / Q000302:isolation & purification
D000907:Antibodies, Bacterial; D007073:Immunoglobulin E