Cystadenolymphoma: an immunohistochemical study with special reference to Ig E and mastcells.
Cystadenolymphomas (adenolymphomas) were analysed by immunohistochemical studies for the presence of immunoglobulin A, E, G and M. The distribution pattern was examined by a quantitative analysis. The relative ratio of immunoglobulins was 31.8% (Ig A), 26.6% (Ig E), 28.6% (Ig G) and 13% (Ig M). The different compartments of the lymphoid stroma were analysed separately (subepithelial area, parafollicular area, follicular area). The distribution of mast cells was studied in a parallel approach by the toluidine blue technique. These cells were found in the stroma, but also in the epithelial parts. Our results show that the subepithelial zone in cystadenolymphomas is a region of special cellular reaction (plasma cells, mast cells). The Ig E producing plasma cells and the mastcells seem to play a special role in these tumors.
D000235:Adenolymphoma / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007073:Immunoglobulin E / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis*; D008407:Mast Cells / Q000166:cytology / Q000276:immunology*; D010306:Parotid Gland / Q000276:immunology; D012468:Salivary Gland Neoplasms / Q000276:immunology* / Q000473:pathology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D007073:Immunoglobulin E