The evolution of perforating folliculitis in patients with chronic renal failure.
The evolution of perforating folliculitis in six patients with chronic renal failure was investigated with special attention to clinical and histopathologic changes in early, evolving, and mature lesions. Different and distinct histologic features at each stage were found. The earliest lesions, follicular pustules, evolved into perforating folliculitis that eventuated in prurigo nodularis. A combined treatment consisting of an anti-staphylococcal antibiotic by mouth, phototherapy, and application of a topical corticosteroid lotion proved helpful in controlling the generalized pruritus and the evolution of the lesions in these cases.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D005260:Female; D005499:Folliculitis / Q000209:etiology / Q000473:pathology* / Q000628:therapy; D006197:Hair / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009824:Ointments; D010789:Phototherapy; D011536:Prurigo / Q000209:etiology / Q000473:pathology; D012867:Skin / Q000473:pathology; D012874:Skin Diseases, Infectious / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D009824:Ointments