title: Peters' anomaly in association with ring 21 chromosomal abnormality.
abstract: A white boy, born at the gestational age of 39 weeks, had Peters' anomaly in association with a ring 21 chromosomal abnormality. Dysmorphic features included low-set ears, hypoplastic mandible, delicate, dry skin, narrow arched palate, wide spaced nipples and hypotonia. He also had a cloudy right cornea. Chromosomal analysis disclosed a ring 21 defect. The cornea had a paracentral white opacity with a loss of posterior stroma and no adherence of the iris to the leukoma. Intraocular pressure, the lens, and the posterior pole were normal.
mesh_terms: D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002904:Chromosomes, Human, 21-22 and Y; D003315:Cornea / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D008297:Male