Loss of biological and immunological activity of oxytocin from goat plasma on storage.
Storage of plasma at -30 degrees C, with no prior treatment, resulted in significant (P less than 0.01) reductions in the biological and immunological activities of oxytocin after 10 days and further reductions after 20 days. Acidification with 0.1 N hydrochloric acid, or snap-freezing in solid carbon dioxide-acetone, before storage afforded some protection against these losses and a combination of both treatments preserved the biological and immunological activities for 20 days despite thawing and refreezing after 10 days.
D000818:Animals; D001793:Blood Preservation; D005615:Freezing; D006041:Goats / Q000097:blood*; D006863:Hydrogen-Ion Concentration; D010121:Oxytocin / Q000097:blood* / Q000276:immunology
D010121:Oxytocin