[Adaptive reactions of the thyroid system in patients with ischemic heart disease to graded physical exertion].
Data reflecting thyroid response to rationed exercise (bicycle ergometry) in coronary patients are presented with respect to physical stress tolerance and clinical form of coronary disease. The results were compared with those obtained in healthy untrained male subjects. Exercise was carried on until submaximum capacity was reached, or clinical and/or electrocardiographic signs of coronary insufficiency appeared. Radioimmune assays of blood thyrotropin and total triiodothyronine (T3) and thyroxin (T4) were made in the course of exercise. Patients with better functional capacity were shown to develop the relatively-low T3 syndrome. A direct correlation was demonstrated between the T4/T3 index and the threshold effort. Patients with low stress tolerance showed increased T3 secretion and depressed T4/T3 at the peak of exercise.
D000222:Adaptation, Physiological; D003327:Coronary Disease / Q000503:physiopathology*; D005080:Exercise Test; D006801:Humans; D008297:Male; D005082:Physical Exertion; D013961:Thyroid Gland / Q000503:physiopathology*; D013972:Thyrotropin / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D014284:Triiodothyronine; D013972:Thyrotropin
Adaptatsionnye reaktsii tireoidnoĭ sistemy u bol'nykh ishemicheskoĭ bolesn'iu serdtsa na dozirovannuiu fizicheskuiu nagruzku.