title: Pattern-reversal electroretinograms in ocular hypertension.
abstract: Pattern-reversal electroretinograms (ERGs) were recorded from seven patients, aged 50 to 69 years, with clinical diagnosis of unilateral ocular hypertension. In four of the seven patients the pattern ERG amplitude from the hypertensive eye was reduced below the normal level of variability, when compared with the amplitude from the opposite normotensive eye (ratio less than 0.8). In three of these four cases excavation of the optic disk in the hypertensive eye was observed 6 to 15 months after the recording of reduced pattern ERG. The finding suggests that pattern ERG may be an useful objective method for early detection of functional damage in eyes with increased intraocular pressure.
mesh_terms: D000328:Adult; D000368:Aged; D004596:Electroretinography / Q000379:methods*; D005901:Glaucoma / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009798:Ocular Hypertension / Q000150:complications / Q000503:physiopathology*