title: [Diagnostic informative value of the method of competitive transcortin binding for determining corticosteroid levels in hypercorticism].
abstract: The level of nonmetabolized forms of the corticosteroids hydrocortisone and corticosterone in the blood and urine were determined in 3 groups of patients: with the Icenko-Cushing disease and syndrome and neuroendocrine form of the hypothalamic syndrome. The determination of the level of these hormones, a study of their circadian rhythm by the method of concurrent protein binding have shown that these indices are rather informative and can be recommended as diagnostic and differential criteria for the evaluation of the hypothalamo-hypophyseal-adrenal system.
mesh_terms: D015065:17-Hydroxycorticosteroids / Q000652:urine*; D000328:Adult; D001667:Binding, Competitive; D003345:Corticosterone / Q000378:metabolism*; D003480:Cushing Syndrome / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D008875:Middle Aged; D011485:Protein Binding; D014156:Transcortin / Q000378:metabolism*
chemical_list: D015065:17-Hydroxycorticosteroids; D014156:Transcortin; D003345:Corticosterone; D006854:Hydrocortisone
vernacular_title: Diagnosticheskaia informativnost' metoda konkurentnogo sviazyvaniia transkortinom dlia opredeleniia kortikosteroidov pri giperkortitsizme.