title: The validity of neurotic-reactive depression. New data and reappraisal.
abstract: A family history of alcoholism can be used as a validating factor in the diagnosis of reactive-neurotic depression. Not only is this true but there are clear data that indicate the presence of positive symptoms that can be used to make the diagnosis. A set of criteria based on previous research is presented for the diagnosis of neurotic-reactive depression. These criteria are based on a clustering of certain symptoms, events, and traits in patients with neurotic-reactive depression. The patients showed stormy life-styles, some specific symptoms, personality abnormalities, presence of life events before the onset of depression, and a family history of alcoholism. They had relatively few hospitalizations for depression and responded poorly to specific antidepressant treatment.
mesh_terms: D000275:Adjustment Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D000328:Adult; D000437:Alcoholism / Q000175:diagnosis / Q000235:genetics; D000928:Antidepressive Agents / Q000627:therapeutic use; D003866:Depressive Disorder / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D003937:Diagnosis, Differential; D005260:Female; D006760:Hospitalization; D006801:Humans; D008016:Life Change Events; D008019:Life Style; D008370:Manuals as Topic; D008875:Middle Aged; D010554:Personality Disorders / Q000175:diagnosis / Q000523:psychology; D011569:Psychiatric Status Rating Scales
chemical_list: D000928:Antidepressive Agents