Duodenal perforation associated with tolazoline.
A neonate, managed with tolazoline for pulmonary hypertension after repair of a congenital diaphragmatic hernia, developed a duodenal perforation. The role of tolazoline in this condition is discussed, and possible measures to reduce its gastrointestinal side effects are proposed.
D004378:Duodenal Diseases / Q000139:chemically induced*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy; D007231:Infant, Newborn; D007416:Intestinal Perforation / Q000139:chemically induced*; D008297:Male; D014043:Tolazoline / Q000009:adverse effects* / Q000627:therapeutic use
D014043:Tolazoline