[Autoimmune hemolysis caused by anti-Pr].
Following an infection with mycoplasma pneumoniae, an anti-Pr-antibody developed in a hitherto healthy man, aged 41. Within a period of 5 days the antibody caused a severe autoimmune hemolytic reaction. The patient died on the fifth day after admission due to hemolysis and uremia. The autoantibody showed a reactivity with a broad thermal range from 4 degrees C to 37 degrees C. As an initial warning sign, the patient presented an expressed livedo reticularis. Massive wholeblood exchanges could not stop the fatal process.
D000328:Adult; D000373:Agglutinins / Q000032:analysis*; D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology*; D000918:Antibody Specificity; D001788:Blood Grouping and Crossmatching; D003450:Cryoglobulins; D004912:Erythrocytes / Q000276:immunology; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D008297:Male; D011019:Pneumonia, Mycoplasma / Q000276:immunology
D000373:Agglutinins; D003450:Cryoglobulins; C029443:cold agglutinins
Autoimmunhämolyse durch Anti-Pr.