title: The treatment of Parkinson's disease.
abstract: In the management of Parkinson's disease physicians now have at their disposal a number of useful therapeutic tools (Figure 3). (Formula: see text) Anticholinergic drugs and amantadine suffice in the early stages of the disease when little disability is present. Levodopa combined with a peripheral decarboxylase inhibitor is the treatment of choice thereafter, and with the appearance of fluctuations it is necessary to increase the frequency of dosage of levodopa and to consider adding bromocriptine. Stereotactic surgery is useful in patients with severe tremor which is unresponsive to drug therapy.
mesh_terms: D000368:Aged; D001971:Bromocriptine / Q000627:therapeutic use; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors; D006801:Humans; D007980:Levodopa / Q000009:adverse effects / Q000627:therapeutic use*; D009069:Movement Disorders / Q000139:chemically induced; D009325:Nausea / Q000139:chemically induced; D010300:Parkinson Disease / Q000188:drug therapy* / Q000503:physiopathology; D011605:Psychoses, Substance-Induced
chemical_list: D001971:Bromocriptine; D007980:Levodopa; D002262:Carboxy-Lyases