Lithium effects on selected circadian rhythms in rats.
Treating rats with lithium results in clear phase-delays in certain circadian rhythms but has no effect upon other rhythms. Phase-delays can be seen in running-wheel activity rhythms but under certain conditions, phase changes are not noted in SCN 2-DG uptake or pineal melatonin rhythms.
D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D002940:Circadian Rhythm / Q000187:drug effects*; D003847:Deoxyglucose / Q000378:metabolism; D008094:Lithium / Q000494:pharmacology*; D008297:Male; D008550:Melatonin / Q000378:metabolism; D009043:Motor Activity / Q000187:drug effects; D010870:Pineal Gland / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013493:Suprachiasmatic Nucleus / Q000187:drug effects
D008094:Lithium; D003847:Deoxyglucose; D008550:Melatonin