title: Sustained release theophylline for the forgetful asthmatic.
abstract: Several theophylline pharmacologic strategies were tested for the forgetful medication-dependent asthmatic who frequently initiates treatment from below the therapeutic range of 10 to 20 micrograms/mL. Theodur was found to give comparable if not higher levels (two, eight, and 24 hours) starting from 0 microgram/mL than Slophyllin Gyrocap during a multiple dose 28-hour study. In a single dose 12-hour study, Theodur 100-mg tablets gave higher levels during the first nine hours than Theodur 200-mg tablets. Theodur 100-mg tablets may be preferred for the forgetful asthmatic who can sustain pulmonary function despite greater fluctuation with theophylline levels.
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000188:drug therapy* / Q000523:psychology; D002648:Child; D003692:Delayed-Action Preparations; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D010349:Patient Compliance; D013806:Theophylline / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*
chemical_list: D003692:Delayed-Action Preparations; D013806:Theophylline