title: [Unintended effects of oral contraceptives. I.Estrogen-related effects].
abstract: Oral contraceptives are almost optimally effective but not yet perfectly safe. They can cause favourable or adverse unintended effects which cannot always be attributed to either the estrogen or the progestagen; however, in many instances a fair differentiation is possible. Type, intensity and frequency of side effects depend on dosage, duration of administration and on the structure of the substance. Some favourable side effects of estrogens are used for therapeutic purposes. Adverse side effects of estrogens are either subjectively disturbing only, or medically important, but few are life threatening. Dose dependence has been established, a structure relationship is unlikely.
mesh_terms: D001835:Body Weight / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000139:chemically induced*; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006130:Growth Disorders / Q000139:chemically induced; D006801:Humans; D008113:Liver Neoplasms / Q000139:chemically induced; D012725:Sexual Behavior / Q000187:drug effects; D013923:Thromboembolism / Q000139:chemically induced*; D002583:Uterine Cervical Neoplasms / Q000139:chemically induced
chemical_list: D003278:Contraceptives, Oral, Hormonal
vernacular_title: Unbeabsichtigte Wirkungen der oralen Kontrazeptiva. I. Ostrogenbedingte Effekte.