Corneal ulcer after exposure to vapours from bone cement (methyl methacrylate and hydroquinone).
An operation nurse repeatedly developed a corneal ulcer while mixing bone cement. It is suggested that the ulcer developed because of a composite effect of vapours from bone cement (methyl methacrylate monomer and hydroquinone), in spite of the fact that the Occupational Health Guidelines and the national threshold limit values for chemical substances had been respected. In-vitro and in-vivo animal studies are reviewed.
D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001843:Bone Cements / Q000009:adverse effects*; D003320:Corneal Ulcer / Q000139:chemically induced*; D005260:Female; D006801:Humans; D006873:Hydroquinones / Q000009:adverse effects; D020366:Methylmethacrylate; D008768:Methylmethacrylates / Q000009:adverse effects; D009726:Nurses; D009784:Occupational Diseases / Q000139:chemically induced*; D009873:Operating Rooms
D000395:Air Pollutants, Occupational; D001843:Bone Cements; D006873:Hydroquinones; D008768:Methylmethacrylates; D020366:Methylmethacrylate; C031927:hydroquinone