Characterization of a Yersinia enterocolitica antigen common to enterocolitis-associated serotypes.
Yersinia enterocolitica synthesized an exocellular antigen common to the serotypes associated with enterocolitis but absent from other serotypes or from other Yersinia species. Both virulent Ca2+-dependent and avirulent Ca2+-independent isogenic pairs derived from the enterocolitis-associated serotypes synthesized the common antigen. Requirements for the synthesis of this common antigen were (i) the presence of metabolizable sugars and (ii) growth on a solid medium at 37 degrees C. The antigen was identified as a 24,000-dalton protein loosely associated with the cell surface but absent from either the cell envelope or the cytoplasmic fraction.
D000818:Animals; D000942:Antigens, Bacterial / Q000302:isolation & purification*; D002118:Calcium / Q000494:pharmacology; D004751:Enteritis / Q000382:microbiology*; D006801:Humans; D007122:Immunoelectrophoresis; D008970:Molecular Weight; D012703:Serotyping; D015009:Yersinia Infections / Q000276:immunology*; D015008:Yersinia enterocolitica / Q000145:classification / Q000276:immunology* / Q000472:pathogenicity
D000942:Antigens, Bacterial; D002118:Calcium