title: [Histopathological studies in young Lymnae glabra Müller of live or of abortive infestation].
abstract: Very young snails had been individually exposed to a single miracidium of Fasciola hepatica; they were bred at 23 degrees C during 49 days and killed at days 42 and 49 postexposure for histological studies. Tissue lesions were observed in six organs of infected snails and none in uninfected and control snails. All snails with living parthenitae showed a necrotized and atrophic gonad; a reconstitution with epithelial hyperplasia was noted in the most digestive glands, kidneys and genital annex glands of these snails. Variable tissue lesions occurred in organs of snails with abortive infections: the lesions - i.e. necrosis of epithelial cells followed by a reconstitution with cell hyperplasia - were often seen in the kidneys, more rarely in the other organs. No lesions in ventricle and no amoebocytic reaction were found in all these snails. Cells of nerve ganglia showed a dense and homogeneous coloration in 53% of infected snails and a normal colored structure in the others. Epithelial reconstitution of organs was only seen in infected snails with a higher shell at the end of experiment, epithelial necrosis in infected ones with a variable shell height.
mesh_terms: D000818:Animals; D001284:Atrophy; D004064:Digestive System / Q000473:pathology; D005210:Fasciola hepatica; D007668:Kidney / Q000473:pathology; D008195:Lymnaea / Q000469:parasitology*; D008297:Male; D009336:Necrosis; D011467:Prostate / Q000473:pathology
vernacular_title: Etudes histopathologiques chez de jeunes Lymnae glabra Müller avec une infestation évolutive ou abortive.