Controlled exposure to a mixture of SO2, NO2, and particulate air pollutants: effects on human pulmonary function and respiratory symptoms.
Exposure of 20 volunteers to sodium chloride (NaCl) aerosol or to a mixture containing NaCl plus irritant particles (zinc ammonium sulfate) and irritant gases (nitrogen dioxide and sulfur dioxide) produced no significant decrements in pulmonary function. There was a slight tendency for respiratory symptoms to be greater during the exposure to the mixture than during exposure to the NaCl aerosol alone; the differences were not statistically significant. The pollutant concentrations studied approximated worst-case ambient levels observed in the Los Angeles basin.
D000293:Adolescent; D000328:Adult; D000336:Aerosols; D000393:Air Pollutants / Q000032:analysis / Q000633:toxicity*; D000645:Ammonium Sulfate / Q000633:toxicity; D005260:Female; D006801:Humans; D008168:Lung / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009585:Nitrogen Dioxide / Q000633:toxicity*; D012120:Respiration Disorders / Q000139:chemically induced*; D012965:Sodium Chloride / Q000633:toxicity; D013458:Sulfur Dioxide / Q000633:toxicity*; D015032:Zinc / Q000633:toxicity; D017967:Zinc Compounds
D000336:Aerosols; D000393:Air Pollutants; D017967:Zinc Compounds; D013458:Sulfur Dioxide; C031251:zinc ammonium sulfate; D012965:Sodium Chloride; D015032:Zinc; D009585:Nitrogen Dioxide; D000645:Ammonium Sulfate