Ocular manifestations of sickle cell disease in Nigerians; experience in Benin City, Nigeria.
The ocular findings in 50 cases of homozygous sickle cell disease are reported. Ocular abnormalities were found in 45 (90%) of them. Conjunctival vascular anomalies, tortuosity of the retinal vessels, particularly the veins and pigmented chorioretinal lesions were the commonest ocular manifestations; central retinal artery occlusion was found in one patient. Angioid streaks, retinitis proliferans and retinal detachment were not observed. Visual acuity was normal in 49 out of 50 patients; the exception was the patient with central artery occlusion.
D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000453:epidemiology / Q000503:physiopathology; D002648:Child; D003228:Conjunctiva / Q000473:pathology; D003229:Conjunctival Diseases / Q000453:epidemiology / Q000209:etiology; D005128:Eye Diseases / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D009549:Nigeria; D011446:Prospective Studies; D014792:Visual Acuity