title: [Blood glucose, C-peptide and glucagon levels in patients with a labile course of diabetes mellitus during use of the device "Biostator"].
abstract: Altogether 100 patients with insulin-dependent diabetes mellitus of a labile course were treated using the Biostator unit (artificial pancreas). The control group (20 persons) was treated with divided doses of insulin within a day. A study was made of glycemia, the range of its deviations, daily glucosuria, diuresis, the basal level of C-peptide and glucagon in the study and control groups prior to and after treatment. Statistically significant improvement of the values in the study group was observed, that, in the authors' opinion, can be attributed to the improvement of insulin-glucagon ratio at the expense fo an increase in the basal secretion of C-peptide as a result of the use of the artificial pancreas.
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D002096:C-Peptide / Q000097:blood*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D005934:Glucagon / Q000097:blood*; D006801:Humans; D007332:Insulin Infusion Systems; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D002096:C-Peptide; D005934:Glucagon
vernacular_title: Dinamika glikemii, urovnia C-peptida i gliukagona u bol'nykh s labil'nym techeniem sakharnogo diabeta na fone ispol'zovaniia apparata "Biostator".