Adult onset Still's disease in the elderly: a report of two cases.
Two patients with the first symptoms of adult onset Still's disease in their 7th decade are reported. In both cases their advanced age was a main reason for a prolonged delay in diagnosis. Besides the characteristic fever pattern, rash and arthritis, our patients showed other typical features of Still's disease such as splenomegaly, pleuritis, pneumonitis, carpal ankylosis and leukocytosis. In addition both showed marked hepatic abnormalities which seemed to be due to the disease itself in one case and at least in part related to exposure to phenylbutazone and diclofenac in the other.
D000368:Aged; D001168:Arthritis / Q000209:etiology; D001171:Arthritis, Juvenile / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury; D003937:Diagnosis, Differential; D004008:Diclofenac / Q000009:adverse effects; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D007964:Leukocytosis / Q000209:etiology; D008107:Liver Diseases / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010653:Phenylbutazone / Q000009:adverse effects; D010998:Pleurisy / Q000209:etiology; D011859:Radiography; D012871:Skin Diseases / Q000209:etiology; D013163:Splenomegaly / Q000209:etiology
D004008:Diclofenac; D010653:Phenylbutazone