Two-dimensional J-resolved nuclear magnetic resonance spectral study of two bromobenzene glutathione conjugates.
The application of two-dimensional J-resolved nuclear magnetic resonance spectroscopy to determine the structure of two bile metabolites isolated from rats injected interperitoneally with bromobenzene is described. The structures of the two molecules are obtained unambiguously from the proton-proton spin coupling constants. This paper discusses the fundamentals of the technique and demonstrates the resolution of small long-range coupling constants.
D000818:Animals; D001969:Bromobenzenes / Q000378:metabolism*; D005978:Glutathione / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D051381:Rats
D001969:Bromobenzenes; D005978:Glutathione