title: Local specific IgE production in nasal polyps associated with negative skin tests and serum RAST.
abstract: Eighteen of 24 patients undergoing nasal polypectomies demonstrated polyp fluid total IgE higher than corresponding serum values. Allergen-specific IgE was detected in polyp fluid of 19/24 patients. Since only 9/19 had positive skin tests, ten patients had specific IgE locally in polyp tissue which could not be detected systemically.
mesh_terms: D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis; D007073:Immunoglobulin E / Q000378:metabolism*; D009298:Nasal Polyps / Q000276:immunology*; D011852:Radioallergosorbent Test; D012882:Skin Tests
chemical_list: D007073:Immunoglobulin E