[Isolation and identification of metabolites of 5-ethyl-2'-deoxyuridine from rat urine].
The metabolites of 5-ethyl-2'-deoxyuridine (Aedurid) have been isolated and purified from rat urine by preparative thin-layer and column chromatography. With the aid of 1H-NMR and mass spectroscopy and by comparison with an authentic sample, the major metabolite could be identified as 5-(1-hydroxyethyl)uracil. The minor metabolite was identified as 5-ethyluracil.
D000818:Animals; D000998:Antiviral Agents / Q000652:urine*; D001711:Biotransformation; D002855:Chromatography, Thin Layer; D003857:Deoxyuridine / Q000031:analogs & derivatives* / Q000652:urine; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051381:Rats
D000998:Antiviral Agents; C022811:edoxudin; D003857:Deoxyuridine
Isolierung und Identifizierung der Metaboliten von 5-Ethyl-2'-desoxyuridin aus Rattenurin.