title: Purification and complete amino acid sequence of canine pancreatic secretory trypsin inhibitor.
abstract: Pancreatic secretory trypsin inhibitor (PSTI) was purified from canine pancreatic juice by HPLC. Canine PSTI inhibited bovine trypsin activity stoichiometrically and strongly with a dissociation constant of below 10(-9) M. The amino acid sequence of canine PSTI was determined by conventional methods. It had one more amino acid residue at the amino-terminus than other mammalian PSTIs, i.e. human, porcine, bovine and ovine.
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D004285:Dogs; D006801:Humans; D010189:Pancreatic Juice / Q000032:analysis*; D012756:Sheep; D013552:Swine; D014357:Trypsin / Q000378:metabolism; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000302:isolation & purification* / Q000494:pharmacology; D014361:Trypsin Inhibitors / Q000302:isolation & purification*
chemical_list: D014361:Trypsin Inhibitors; D014359:Trypsin Inhibitor, Kazal Pancreatic; D014357:Trypsin