[Changes in the chondriome during the cell cycle of a tissue culture of embryonic pig kidney].
The regular cyclic changes of number, size, shape and ultrastructure of cells mitochondria during G1, S, G2-periods and mitosis have been shown by morphometric methods on nonsynchronized culture of PEK tissue. Number of mitochondria is equal in G1 and S cells. Middle size and unbranched mitochondria prevail in G1-period, middle size and large organellae of complicated shape are characteristic for S-period. In G2-period number of mitochondria increases in 1,5 times. Simultaneously the portion of middle and small unbranched mitochondria increases and number of large organellae of complicated shape decreases. Number of mitochondria in mitotic cells in comparison with cells of G2-period does not change distinctly. Most mitochondria are middle and small size, usually unbranched in this period. Considerable increase of mitochondria number in G2-period is probably due to division of the branched mitochondria characteristic for the previous S-period. The mitochondria ultrastructure does not undergo marked changes during the interphase of the cell-cycle and characterizes by prevailing of the orthodox forms of mitochondria: in late G2-period and in the process of mitosis the most mitochondria become condensed.
D000818:Animals; D002453:Cell Cycle; D002460:Cell Line; D046508:Culture Techniques; D007399:Interphase; D007668:Kidney; D008928:Mitochondria / Q000648:ultrastructure*; D008938:Mitosis; D013552:Swine
Izmeneniia khondrioma v khode kletochnogo tsikla kul'tury tkani SPEV.