Serum ferritin in type I diabetes.
The concentration and degree of glycosylation of serum ferritin was evaluated in type I male diabetic patients at different levels of glycaemic control. Serum ferritin did not appear to be affected by hyperglycaemia, but some patients undergoing photocoagulation had abnormally high levels of serum ferritin. The glycosylated, (concanavalin A binding), proportion of serum ferritin was essentially the same in the control and diabetic groups. The finding that hyperglycaemia does not affect the degree of enzymatic glycosylation of this serum protein is discussed.
D000293:Adolescent; D000328:Adult; D002241:Carbohydrates / Q000032:analysis; D003208:Concanavalin A / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D003930:Diabetic Retinopathy / Q000628:therapy; D005293:Ferritins / Q000097:blood*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010789:Phototherapy
D002241:Carbohydrates; D003208:Concanavalin A; D005293:Ferritins; D006442:Glycated Hemoglobin