[Effect of postoperative human albumin therapy on serum protein fraction of septic and aseptic patients].
The effects of 20 and 40 g postoperative intravenous human albumin (HA) infusion on the serum protein fractions and on the colloid osmotic pressure (COP) were analyzed in 72 septic and aseptic patients. Only aseptic patients showed an increase in the COP as well as the serum albumin concentration during at least a 24-h-period. In septic patients, however, the increased serum albumin concentration dropped rapidly to the initial values. This can be only explained by a disturbance of the membrane permeability. In contrast, the behavior of the serum globulin concentration was not essentially influenced by septic or non septic conditions.
D000328:Adult; D000368:Aged; D001780:Blood Coagulation Tests; D001798:Blood Proteins / Q000378:metabolism*; D003422:Critical Care; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006400:Hematocrit; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012709:Serum Albumin / Q000008:administration & dosage*; D012712:Serum Globulins / Q000378:metabolism; D013530:Surgical Wound Infection / Q000097:blood* / Q000628:therapy; D014882:Water-Electrolyte Balance
D001798:Blood Proteins; D008055:Lipids; D012709:Serum Albumin; D012712:Serum Globulins; D005340:Fibrinogen
Der Einfluss einer postoperativen Humanalbumintherapie auf die Serumeiweissfraktion septischer und aseptischer Patienten.