title: Efficacy of morantel tartrate in a sustained release bolus on the control of subclinical gastrointestinal parasitism in first-year grazing dairy replacements.
abstract: Thirty-four heifers (24 Holstein, 8 Ayrshire, 2 Jersey) and 12 Holstein steer calves were grouped into 23 blocks of 2 animals each according to breed, sex, and body weight. Animals in each block were randomly assigned to control or treated groups. The treated group received an anthelmintic bolus containing morantel tartrate before they were permitted access to pasture. A 2.6 ha pasture was divided in half with a double fence; the resulting two pastures had separate feed and water troughs. Steer calves were slaughtered upon termination of the trial to ascertain gastrointestinal parasite burdens. Two worm-free tracer calves were placed on each pasture every 2 mo and slaughtered after 4 wk of grazing to determine parasite infectivity of pastures. Herbage samples were obtained monthly and analyzed for infective larvae. The trial was conducted for 141 d during the grazing season. Treatment resulted in 90% reduction in infective larvae on pasture, 74% reduction in fecal worm-eggs, 91% reduction in adult worm burdens, and a trend toward reduced worm burdens in tracer calves by 52%. An overall average daily gain of .68 and .88 kg was obtained for control and treated animals. Reproductive data for the heifers remaining in the herd from the trial showed that treatment resulted in 44 less days to first breeding.
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002417:Cattle / Q000254:growth & development / Q000469:parasitology; D002418:Cattle Diseases / Q000469:parasitology / Q000517:prevention & control*; D003692:Delayed-Action Preparations; D005260:Female; D007411:Intestinal Diseases, Parasitic / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*; D007814:Larva; D008297:Male; D009015:Morantel / Q000008:administration & dosage*; D009348:Nematoda / Q000302:isolation & purification; D009349:Nematode Infections / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*; D010270:Parasite Egg Count; D011743:Pyrimidines / Q000008:administration & dosage*; D012621:Seasons
chemical_list: D003692:Delayed-Action Preparations; D011743:Pyrimidines; D009015:Morantel