Conditioned suppression of sexual behavior in stallions and reversal with diazepam.
Sexual behavior dysfunction unaccompanied by detectable physical or endocrine abnormality is an important cause of reproductive failure among domestic stallions. Several authors have suggested that such dysfunction may be psychogenic, related to negative experience associated with intense handling and training. An experimental model of experience-related dysfunction was developed by exposing pony stallions to erection-contingent aversive conditioning. This resulted in rapid, specific suppression of sexual arousal and response similar to spontaneously occurring dysfunction. Subsequently, treatment with a CNS-active benzodiazepine derivative (diazepam) reversed these effects.
D000818:Animals; D001362:Avoidance Learning; D003975:Diazepam / Q000494:pharmacology*; D004597:Electroshock; D006736:Horses; D008297:Male; D012726:Sexual Behavior, Animal
D003975:Diazepam