Zomepirac-induced anaphylactic shock: an under-reported phenomenon.
Two patients presented with signs and symptoms of apparent zomepirac-induced anaphylactic shock. All recovered with appropriated therapy. The theories of the mechanisms by which nonsteroidal anti-inflammatory drugs cause this serious adverse reaction are discussed.
D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced*; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D011758:Pyrroles / Q000009:adverse effects*; D014046:Tolmetin / Q000009:adverse effects* / Q000031:analogs & derivatives
D000893:Anti-Inflammatory Agents; D011758:Pyrroles; C020549:zomepirac; D014046:Tolmetin