The possible relationship between hepatic drug metabolism and ketoconazole enhancement of cyclosporine nephrotoxicity.
D000818:Animals; D003524:Cyclosporins / Q000633:toxicity*; D004347:Drug Interactions; D007654:Ketoconazole / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects*; D008099:Liver / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains
D003524:Cyclosporins; D007654:Ketoconazole