title: [Value of biopsy and directed brush cytology in gastrointestinal cancer diagnosis based on 1979-1984 endoscopies].
abstract: The results during the period 1979-1984 of intestinal endoscopies with brush cytology and biopsy of the same lesion at the same time were evaluated to define the value of these methods. Results were reported as "cancer present" or "not present" or as "suspicious/proving" versus "nonsuspicious for cancer" and were analyzed separately. Biopsy was shown to be of greater sensitivity than cytology in the stomach and cytology more sensitive in the colon. The combination of biopsy and cytology improved sensitivity, especially in the esophagus, small intestine and colon, and may help to dispense with unnecessary repetitions of endoscopic evaluations. The specificity was found to be extremely high when the results were reported as "cancer present" or "not present", with only one false positive report in a patient with ischemic colitis. In more than 60% the final diagnosis was cancer if the initial report showed suspicion of cancer, but the specificity of these results was low.
mesh_terms: D001706:Biopsy; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005773:Gastroscopy; D006801:Humans; D008871:Microvilli / Q000648:ultrastructure*
vernacular_title: Wertigkeit von Biopsie und gezielter Bürstenzytologie bei der gastrointestinalen Karzinomdiagnostik aufgrund der Endoskopien von 1979-1984.