Monthly changes in the effect of BCG on the migration of polymorphonuclear leucocytes.
Monthly changes in the migration of polymorphonuclear leucocytes (PMN) produced by subcutaneous implantation of BCG-impregnated rayone-made disks was examined over a period of 15 months. In experiments carried out at 90h00, the highest PMN count of 40.2 +/- 8.4 PMN/10,000 micrometers2 10,000 micrometers2 was obtained in April. Mechanisms that could explain the circannual variation are suggested.
D000818:Animals; D001500:BCG Vaccine / Q000494:pharmacology*; D002465:Cell Movement; D007958:Leukocyte Count; D008297:Male; D051379:Mice; D009504:Neutrophils / Q000276:immunology*; D012621:Seasons
D001500:BCG Vaccine