Measurement of cerebral blood flow during xenon inhalation as measured by the microspheres method.
Measurements of cerebral blood flow (CBF) were performed using the microsphere technique in non-human primates (baboons) to assess the effect of non-radioactive xenon gas inhalation on CBF. Blood flows in small tissue volumes (approximately 1 cm3) were directly measured before and during the inhalation of xenon/oxygen gas mixtures. The results of these studies demonstrated that when inhaled in relatively high concentrations, xenon gas does increase CBF, but the changes are more global than tissue-specific. The problems and limitations of such evaluations are discussed.
D000818:Animals; D002560:Cerebrovascular Circulation; D005740:Gases; D008722:Methods; D008863:Microspheres; D010100:Oxygen; D010215:Papio; D014978:Xenon
D005740:Gases; D014978:Xenon; D010100:Oxygen