title: [Experience with L-DOPA treatment of children with dystonia musculorum deformans and dystonic hyperkineses in infantile cerebral palsy].
abstract: Nineteen children with dystonia musculorum deformans and dystonic hyperkineses were treated by L-DOPA. A mild positive effect was obtained in 6 children, a considerable positive effect in 9 children. A more marked positive effect was obtained in children with dystonia musculorum deformans. The results indicate the efficiency of L-DOPA in the treatment of dystonia musculorum deformans and dystonic hyperkineses against the residual organic background. The advisability of 2-3 month long courses of therapy with L-DOPA 2-3 times a year is discussed. Some patients may need a continuous therapy with maintenance doses of the drug.
mesh_terms: D000293:Adolescent; D002547:Cerebral Palsy / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004421:Dystonia / Q000188:drug therapy*; D004422:Dystonia Musculorum Deformans / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006948:Hyperkinesis / Q000188:drug therapy*; D007980:Levodopa / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male
chemical_list: D007980:Levodopa
vernacular_title: Opyt lecheniia preparatom L-DOFA deteĭ s deformiruiushcheĭ myshechnoĭ distonieĭ i distonicheskimi giperkinezami pri detskom tserebral'nom paraliche.