title: Microinvasive carcinoma of the vagina: a distinct clinical entity?
abstract: Six patients with superficially invasive squamous carcinoma of the vagina are described. All had less than 2.5 mm of invasion as measured from the surface, lacked involvement of the lymph-vascular spaces, and arose within a field of carcinoma in situ. Three of the six had previously been treated for carcinoma of the cervix. The patients with microinvasive carcinoma had a median age 10 years younger than that of patients with Stage I carcinoma of the vagina. Treatment of the six patients has been by partial or total vaginectomy. With follow-up of 51 to 172 months, there have been no recurrences. More experience is needed to define microinvasive squamous carcinoma of the vagina and to determine the optimal treatment for these lesions.
mesh_terms: D000328:Adult; D000368:Aged; D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008824:Michigan; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D012042:Registries; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery