title: Delayed onset muscle soreness following repeated bouts of downhill running.
abstract: Perceived muscle soreness ratings, serum creatine kinase (CK) activity, and myoglobin levels were assessed in three groups of subjects following two 30-min exercise bouts of downhill running (-10 degrees slope). The two bouts were separated by 3, 6, and 9 wk for groups 1, 2, and 3, respectively. Criterion measures were obtained pre- and 6, 18, and 42 h postexercise. On bout 1 the three groups reported maximal soreness at 42 h postexercise. Also, relative increases in CK for groups 1, 2, and 3 were 340, 272, and 286%, respectively. Corresponding values for myoglobin were 432, 749, and 407%. When the same exercise was repeated, significantly less soreness was reported and smaller increases in CK and myoglobin were found for groups 1 and 2. For example, the percent CK increases on bout 2 for groups 1 and 2 were 63 and 62, respectively. Group 3 demonstrated no significant difference in soreness ratings, CK activities, or myoglobin levels between bouts 1 and 2. It was concluded that performance of a single exercise bout had a prophylactic effect on the generation of muscle soreness and serum protein responses that lasts up to 6 wk.
mesh_terms: D000328:Adult; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D009132:Muscles / Q000502:physiology* / Q000503:physiopathology; D009211:Myoglobin / Q000097:blood; D010101:Oxygen Consumption; D010146:Pain / Q000503:physiopathology; D005082:Physical Exertion; D013997:Time Factors
chemical_list: D009211:Myoglobin; D003402:Creatine Kinase