In vitro susceptibility of pathogenic Vibrio species to norfloxacin and six other antimicrobial agents.
The in vitro activity of norfloxacin and six other antimicrobial agents was tested against 93 vibrio strains representing the currently described pathogenic Vibrio species. Norfloxacin had excellent activity against all species, with the following MICs for 90% of the strains: 0.016 micrograms/ml for Vibrio cholerae (including tetracycline-resistant V. cholerae O1 strains), 0.25 micrograms/ml for V. parahaemolyticus, and 0.063 micrograms/ml for V. vulnificus.
D000667:Ampicillin / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D005839:Gentamicins / Q000494:pharmacology; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology; D009643:Norfloxacin / Q000494:pharmacology*; D013420:Sulfamethoxazole / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology; D014733:Vibrio / Q000187:drug effects*
D005839:Gentamicins; D009268:Nalidixic Acid; D002701:Chloramphenicol; D000667:Ampicillin; D014295:Trimethoprim; D013752:Tetracycline; D013420:Sulfamethoxazole; D009643:Norfloxacin