Skin tests for chymopapain allergy.
Skin prick tests with therapeutic chymopapain (CP) solution, 10 mg/mL, were administered prior to CP injection. Three of 232 (1%) of patients with negative skin tests and 5/6 (83%) of patients with positive skin tests reacted to the therapeutic injection of CP. A positive CP skin test is a contraindication to therapeutic CP injection.
D000707:Anaphylaxis / Q000139:chemically induced; D002917:Chymopapain / Q000008:administration & dosage / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000150:complications / Q000188:drug therapy; D011292:Premedication; D012882:Skin Tests / Q000379:methods
D002917:Chymopapain