title: Malignant edema in horses.
abstract: Malignant edema (clostridial myositis) was diagnosed in 9 horses with signs of illness that included fever, depression, painful muscular swellings, and toxemia. The infection followed intramuscular injections in 8 horses and developed in a puncture wound in 1 horse. Treatment consisted of surgical fenestration of the involved muscle, high doses of penicillin, nonsteroidal anti-inflammatory agents and analgesics, and supportive fluid therapy. Five horses recovered and 4 died. Those that died had advanced signs of the disease at admission.
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003015:Clostridium Infections / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D004487:Edema / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006736:Horses; D006801:Humans; D009220:Myositis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents