[Biologic aging. 23. Endocrine responsibility in the aged as exemplified by glucocorticoid receptors].
In liver cytosol of adrenalectomized female Wistar rats the concentration of unoccupied glucocorticoid binding sites is increased in ageing compared with young animals. The affinity of hormone to the receptor protein ist not changed significantly.
D000315:Adrenalectomy; D000375:Aging; D000818:Animals; D003345:Corticosterone / Q000097:blood; D003600:Cytosol / Q000378:metabolism; D003907:Dexamethasone / Q000097:blood; D005260:Female; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D011965:Receptors, Glucocorticoid / Q000378:metabolism*
D011965:Receptors, Glucocorticoid; D003907:Dexamethasone; D003345:Corticosterone
Zum biologischen Altern. 23. Mitteilung: Endokrine Responsibilität im Alter am Beispiel von Glucocorticoidrezeptoren.