Protein-mediated adhesion of Staphylococcus aureus to silicone implant polymer.
Investigation was made of the role of protein A and clumping factor in the adhesion of Staphylococcus aureus to the silicone polymer used for manufacture of cerebrospinal fluid shunting systems. The two proteins were judged to contribute non-specifically to adhesion. S. aureus was also shown to be capable of hydrophobic binding, but this was found to be distinct from the demonstrated protein-mediated adhesion.
D000268:Adhesiveness; D002557:Cerebrospinal Fluid Shunts; D003030:Coagulase / Q000502:physiology*; D006801:Humans; D012826:Silicone Elastomers; D013203:Staphylococcal Infections / Q000382:microbiology; D013205:Staphylococcal Protein A / Q000502:physiology*; D013211:Staphylococcus aureus / Q000502:physiology*; D014357:Trypsin / Q000494:pharmacology
D003030:Coagulase; D012826:Silicone Elastomers; D013205:Staphylococcal Protein A; D014357:Trypsin