Characteristics of stimulated parotid gland secretion in the aging rat.
The production of pilocarpine-stimulated parotid saliva was evaluated in young adult and aged male and female rats. Parotid salivary flow rate was about 50% lower in aged animals of both sexes. Saliva of aged animals had the same Na+ concentration as that of young rats but contained about 40% more protein. Salivary K+ concentration was similar in young and aged males but not females.
D000375:Aging; D000818:Animals; D001834:Body Water / Q000378:metabolism; D005260:Female; D008297:Male; D010306:Parotid Gland / Q000378:metabolism*; D010862:Pilocarpine / Q000494:pharmacology; D011188:Potassium / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012463:Saliva / Q000378:metabolism; D012471:Salivary Proteins and Peptides / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D013268:Stimulation, Chemical
D012471:Salivary Proteins and Peptides; D010862:Pilocarpine; D012964:Sodium; D011188:Potassium