Fungal peritonitis in patients on continuous ambulatory peritoneal dialysis. Three recoveries in 5 cases without catheter removal.
We attempted to treat 5 patients on CAPD with fungal peritonitis without removing the catheter. In 1 case, amphotericin B caused a severe chemical peritonitis. The other 4 patients received amphotericin B intravenously and miconazole or flucytosine intraperitoneally. Recovery was obtained in 3 cases without removing the catheter and in 1 case the patient died.
D000328:Adult; D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage; D002404:Catheterization / Q000009:adverse effects; D004359:Drug Therapy, Combination; D005260:Female; D005437:Flucytosine / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008825:Miconazole / Q000008:administration & dosage; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000188:drug therapy / Q000209:etiology*
D008825:Miconazole; D000666:Amphotericin B; D005437:Flucytosine