Neuroepithelioma (neuroblastoma) arising in an adult. A case report.
Cytogenetic studies on neuroblastomas arising in children have revealed consistent abnormalities of the short arm of chromosome number 1. Partly because of the rare occurrence of neuroblastomas in adults, extensive cytogenetic studies in this group of patients have not been performed. We report a case of a neuroepithelioma (neuroblastoma) arising in a 50-year-old male patient. On chromosome analysis of a metastasis, a stemline with karyotype 47,XY, +der1 (1 qter---1 cen::1q21---1 qter) was identified. The possible consequences of this result and those of results previously reported in the literature are discussed.
D002869:Chromosome Aberrations; D006801:Humans; D008297:Male; D008875:Middle Aged; D009447:Neuroblastoma / Q000235:genetics* / Q000473:pathology; D010524:Peripheral Nervous System Neoplasms / Q000235:genetics* / Q000473:pathology; D013979:Tibial Nerve