title: [Prosthetic pathology of mechanical and biological valves in the mitral and aortic position. II. Hemodynamic-angiographic evaluation and anatomo-surgical aspects].
abstract: The catheterization parameters of 42 patients with surgically confirmed prosthetic valve malfunction were retrospectively analyzed in order to evaluate the role of hemodynamic and angiocardiographic examination in the diagnosis of prosthetic complications. The invasive investigation provided in all cases more precise informations regarding the type and grade of prosthetic malfunction as compared to noninvasive techniques. Transvalvular gradients could be quantified, the amount of regurgitation could be defined and associated lesions (paraprosthetic aneurysms, aortic root dissection, fistulas secondary to bacterial endocarditis) could be recognized. The surgical exploration confirmed prosthetic malfunction in all cases except two, with fibrous tissue ingrowth: at the moment this complication is not distinguishable from thrombosis and no specific diagnostic signs have been described either with invasive or noninvasive techniques. In our experience the patients who can benefit from hemodynamic examination are: patients with echocardiographic examination of poor technical quality, patients in whom noninvasive investigations can not completely explain the clinical status ("false negative" echocardiograms, multiple prosthetic valves), all cases in whom cardiac surgery requires a precisely detailed evaluation of the prosthetic malfunction. The opportunity or necessity to perform an invasive study in patients with clinically suspected or proven prosthetic malfunction should be discussed individually.
mesh_terms: D000790:Angiocardiography; D001021:Aortic Valve; D001705:Bioprosthesis; D004562:Electrocardiography; D005188:False Negative Reactions; D006350:Heart Valve Prosthesis; D006439:Hemodynamics; D006801:Humans; D008943:Mitral Valve; D011475:Prosthesis Failure; D012189:Retrospective Studies
vernacular_title: Patologia protesica di valvole meccaniche e biologiche in posizione mitralica ed aortica. II. Valutazione emodinamico-angiografica ed aspetti anatomo-chirurgici.