title: Acceleration of ossification by means of interferential current.
abstract: Dynamic interferential current ossification system (DICOS) is a new non-invasive method to accelerate bone growth and repair successfully applied in Europe. As all evaluation methods of clinical bone repair models are too subjective and statistically unreliable, we base our statement on well defined animal experiments with standardized artificial fractures on sheep. Histological, chemical, radiological and electron-microscopic evaluations showed that the higher the interferential current density, the higher: The mineralization of the new bone; The extracellular alkaline phosphatase and The earlier the weight bearing. The electrical field was cross-calculated with computer-aided programs. 4000 Hz alternating current, using the interferential principle; Pleasant current sensation Non-invasive transcutaneous application; Electrode application at any distance from the fracture, even outside the cast; The application is not contraindicated with metal implants being used; No chemical burning under the electrodes; Post-traumatic oedema resorption; Pain relief for patients in cases where analgetics are contraindicated; Acceleration of reinnervation and improvement of microcirculation.
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D002146:Bony Callus / Q000473:pathology; D002478:Cells, Cultured; D004558:Electric Stimulation; D004581:Electronics; D004594:Electrophysiology; D050723:Fractures, Bone / Q000473:pathology / Q000628:therapy; D006801:Humans; D008903:Minerals / Q000378:metabolism; D008938:Mitosis; D010012:Osteogenesis; D011817:Rabbits; D014945:Wound Healing
chemical_list: D008903:Minerals; D000469:Alkaline Phosphatase