title: Comparative studies of the ultrastructure of the sebaceous gland.
abstract: Three-dimensional reconstructions and ultrastructural evidence on the sebaceous glands of man and domestic animals indicate that sebum is produced from a column of developing and degenerating cell populations derived from peripheral progenitor cells at the base of the lobe in a manner analogous to hair growth. The remainder of the peripheral cells apparently have no direct involvement with sebocyte production; those towards the neck of the gland contribute keratin to the secretory product.
mesh_terms: D000328:Adult; D000818:Animals; D002417:Cattle; D005260:Female; D006041:Goats; D006736:Horses; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009919:Orchiectomy; D012627:Sebaceous Glands / Q000648:ultrastructure*; D012756:Sheep