[Study of the aggregation of membrane proteins of erythrocyte ghosts using SDS-PAAG electrophoresis].
Using the method of electrophoresis in SDS-PAAG the authors showed a diminution of proteins of bands I + II (spectrins) and III (major integral protein) after irradiation of erythrocyte ghosts with doses of 50 to 1000 Gy. We failed to ascertain that radiation-induced lipid peroxidation is involved into membrane protein aggregation. Among the radiolysis products, OH-radicals were shown to contribute markedly to the radiation effect observed.
D000818:Animals; D003037:Cobalt Radioisotopes; D004591:Electrophoresis, Polyacrylamide Gel; D004910:Erythrocyte Membrane / Q000528:radiation effects*; D005720:Gamma Rays; D066298:In Vitro Techniques; D008565:Membrane Proteins / Q000528:radiation effects*; D051381:Rats; D013049:Spectrin / Q000528:radiation effects
D003037:Cobalt Radioisotopes; D008565:Membrane Proteins; D013049:Spectrin
Izuchenie agregatsii membrannykh belkov teneĭ éritrotsitov s ispol'zovaniem élektroforeza v DDS-PAAG.