Viability of mature superior cervical ganglia transplants in peripheral nerve of adult rat.
Allografts of mature rat superior cervical ganglia (SCG) survived for up to 120 days following transplantation to regenerating and degenerating peripheral nerves of adult rats. Transplants contained the constituents of normal superior cervical ganglia and there was evidence of outgrowth of catecholamine containing fibers from the transplants. However, fibers did not attain the length necessary to enter peripheral muscles and no muscle response could be elicited by electrical stimulation of the implanted nerve where the transplanted mature SCG was the only source of nerve fibers.
D000818:Animals; D004558:Electric Stimulation; D005728:Ganglia, Sympathetic / Q000637:transplantation*; D006085:Graft Survival; D008297:Male; D009410:Nerve Degeneration; D009416:Nerve Regeneration; D059348:Peripheral Nerve Injuries; D051381:Rats; D011919:Rats, Inbred Strains