title: The distribution and acyl composition of plasmalogens in guinea pig heart.
abstract: In guinea pig heart homogenate, 34% of both choline and ethanolamine phosphoglycerides were in the form of plasmalogens (1-alkenyl, 2-acyl glycerophospholipid). Plasmalogens accounted for 39% of the choline phosphoglycerides and 36% of the ethanolamine phosphoglycerides in the mitochondrial fraction. Ethanolamine plasmalogen was the major ethanolamine phosphoglyceride (63%) in the guinea pig heart microsomal fraction. A high arachidonyl content was found in both diacyl and 1-alkenyl, 2-acyl glycerophosphoethanolamine. The C-2 fatty acyl profiles of the diacyl and 1-alkenyl, 2-acyl choline phosphoglycerides differed considerably from each other in the homogenate as well as in the subcellular fractions. Significant differences in the C-2 fatty acyl profiles also were observed in diacyl and 1-alkenyl, 2-acyl ethanolamine phosphoglycerides. Such differences suggest there is no direct metabolic relationship between the diacyl glycerophosphocholine (-ethanolamine) and its plasmalogen analog.
mesh_terms: D000215:Acylation; D000818:Animals; D006168:Guinea Pigs; D008297:Male; D008861:Microsomes / Q000032:analysis; D008929:Mitochondria, Heart / Q000032:analysis; D009206:Myocardium / Q000032:analysis*; D010713:Phosphatidylcholines / Q000032:analysis; D010714:Phosphatidylethanolamines / Q000032:analysis; D010955:Plasmalogens / Q000302:isolation & purification*; D013347:Subcellular Fractions / Q000032:analysis
chemical_list: D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010955:Plasmalogens