title: Experimental subcutaneous granulomas in sheep with Dermatophilus-like microorganisms from porcine tonsil.
abstract: The pathogenicity of the Dermatophilus-like microorganisms from porcine tonsil and the light and electron microscopic findings were studied with adult ewes. The early lesions were abscessess and advanced ones were granulomas after the subcutaneous inoculation. The granulomas were composed of the central bacterial colonies and the layers of the neutrophils, epithelioid cells and giant cells, and peripheral connective tissues. Epithelioid cells and giant cells were identified by the large euchromatic nuclei, abundant organelles and interdigitation of the blunt pseudopods in the ultrastructure. The lesions were very similar to subcutaneous granulomas in sheep and cattle due to Dermatophilus congolensis (atypical dermatophilosis), actinomycosis and nocardiosis.
mesh_terms: D000193:Actinomycetales Infections / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D005260:Female; D006099:Granuloma / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D008854:Microscopy, Electron; D014066:Palatine Tonsil / Q000382:microbiology*; D012756:Sheep; D012757:Sheep Diseases / Q000473:pathology*; D012867:Skin / Q000473:pathology / Q000648:ultrastructure; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D013552:Swine / Q000382:microbiology*