Is the BANS concept for malignant melanoma valid?
In this study of 427 patients with stage I malignant melanoma seen at the Mayo Clinic between 1973 and 1981, only those patients with complete data with respect to thickness and level of penetration of lesion, morphologic type, and anatomic site were included. Although supporting the widely accepted concept of the prognostic importance of thickness of the lesion, the level of penetration was of much lesser significance in our series, and prophylactic node dissection could not be shown to be of significant benefit. Likewise, the BANS concept proposed by Day et al [1] was not corroborated. The reasons for these discrepancies are not fully apparent, although a preponderance of thin and intermediate thickness lesions in our patients may have had some influence on our results.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D011379:Prognosis; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery