[Morphogenetic characteristics of the mammary glands of autoimmune F1 mice (NZB x NZW)].
The morphogenesis of mammary glands was studied in the normal and autoimmune F1(NZW X NZB) mice. In the lactation cycle of the autoimmune mice the normal course of structural-functional rearrangements of parenchyma and stroma in the developing and involuting mammary glands was disturbed. A conclusion has been reached that the modification of stromal elements, first of all involved in the autoimmune disease, is the leading link in the abnormal development of mammary glands.
D000818:Animals; D001327:Autoimmune Diseases / Q000503:physiopathology*; D004848:Epithelium / Q000503:physiopathology; D005260:Female; D007774:Lactation; D008321:Mammary Glands, Animal / Q000254:growth & development* / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008814:Mice, Inbred NZB / Q000254:growth & development*; D009024:Morphogenesis; D011247:Pregnancy
Osobennosti morfogeneza molochnykh zhelez autoimmunnykh mysheĭ F1 (NZB x NZW).