title: Kidney stones. Medical management and newer options for stone 'removal'.
abstract: Patients with recurrent kidney stone disease or stone formers at increased risk of recurrence deserve a thorough metabolic workup. This should be based on a careful history and include urinalysis, serum chemistry studies, and analysis of 24-hour urine collections. Measures to prevent recurrent stone formation are aimed at correcting the metabolic imbalances detected in the workup. A variety of drugs are available that target one or more of the metabolic abnormalities that may be involved. For "surgically active" renal and ureteral stone disease, newer techniques make surgery unnecessary in most cases. Extracorporeal shock wave lithotripsy is becoming the preferred technique for disintegration of upper urinary tract stones. Percutaneous ultrasonic lithotripsy and electrohydraulic disintegration also are widely used. For lower urinary tract stones, the ureteroscope permits either extraction under visualization or ultrasonic disintegration.
mesh_terms: D000493:Allopurinol / Q000627:therapeutic use; D001581:Benzothiadiazines; D002118:Calcium / Q000652:urine; D002482:Cellulose / Q000031:analogs & derivatives / Q000627:therapeutic use; D002951:Citrates / Q000627:therapeutic use; D019343:Citric Acid; D003558:Cystoscopy; D004232:Diuretics; D005440:Fluid Therapy; D005471:Fluoroscopy; D006801:Humans; D007669:Kidney Calculi / Q000378:metabolism / Q000628:therapy*; D008096:Lithotripsy / Q000379:methods; D008487:Medical History Taking; D008903:Minerals / Q000378:metabolism; D010070:Oxalates / Q000378:metabolism; D010710:Phosphates / Q000627:therapeutic use; D011736:Pyridoxine / Q000627:therapeutic use; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use; D014514:Ureteral Calculi / Q000628:therapy; D014527:Uric Acid / Q000652:urine; D014556:Urine / Q000378:metabolism
chemical_list: D001581:Benzothiadiazines; D002951:Citrates; D004232:Diuretics; D008903:Minerals; D010070:Oxalates; D010710:Phosphates; D049993:Sodium Chloride Symporter Inhibitors; D014527:Uric Acid; D019343:Citric Acid; D000493:Allopurinol; D002482:Cellulose; C008881:phosphocellulose; D011736:Pyridoxine; D002118:Calcium