title: [Long-term prognosis of drug and surgery treated patients with acquired aortic valve diseases: survival statistics and multivariate Cox regression analysis].
abstract: Data of 417 patients with advanced chronic aortic valve disease were retrospectively analyzed using a life table and Cox regression analysis. Aortic valve replacement was recommended to all patients based on clinical and hemodynamic findings. While most patients underwent prosthetic aortic valve replacement (n = 349), a minority of patients was treated medically (n = 68). Prognosis was better (p less than 0.01 in the Cox model) in surgically treated as compared to medically treated patients with aortic stenosis (4-year survival rate 82 versus 44%). In patients with aortic insufficiency no significant difference of long-term prognosis was found between surgically and medically treated patients.
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001022:Aortic Valve Insufficiency / Q000188:drug therapy / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000188:drug therapy / Q000601:surgery*; D001705:Bioprosthesis; D004071:Digitalis Glycosides / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D011379:Prognosis; D012044:Regression Analysis
chemical_list: D000900:Anti-Bacterial Agents; D004071:Digitalis Glycosides; D004232:Diuretics
vernacular_title: Langzeitprognose medikamentös und chirurgisch behandelter Patienten mit erworbenen Aortenklappenfehlern: Uberlebensstatistik und multivariate Cox-Regressionsanalyse.