Peptides released by ameboid microglia regulate astroglial proliferation.
Peptides that stimulate astroglial proliferation are produced in traumatized adult rat brain by 10 d after injury. These same peptides are released by ameboid microglia activated in vitro. Our findings suggest that astroglial scarring is regulated in part by the release of factors from ameboid microglia near the site of brain injury.
D000818:Animals; D001930:Brain Injuries / Q000473:pathology*; D002448:Cell Adhesion; D002455:Cell Division; D002478:Cells, Cultured; D020904:Glia Maturation Factor; D006133:Growth Substances / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000502:physiology*; D009457:Neuroglia / Q000166:cytology / Q000502:physiology*; D051381:Rats; D014945:Wound Healing
D020904:Glia Maturation Factor; D006133:Growth Substances; D009419:Nerve Tissue Proteins