Oscillating tolerance in synchronized cultures of Staphylococcus aureus.
Cells of synchronized cultures of Staphylococcus aureus showed an oscillating MBC/MIC ratio when tested with penicillin G. Although the MICs did not differ significantly throughout the cell cycle, the MBC was at its maximum when actively dividing cells were inoculated.
D002453:Cell Cycle; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D010507:Periodicity; D013211:Staphylococcus aureus / Q000187:drug effects*