title: Activity of erythrocyte alanine aminotransferase in the Polish population.
abstract: Alanine aminotransferase activities were tested in erythrocytes of Polish population sample of 213 adults (105 women and 108 men) and 95 children (aging 6 months to 4 years). In the tests a modified method of Wróblewski and Cabaud was used. A significant scatter of enzyme activities was noted, which ranged in adults between 0.76 and 36.86 mU/ml. In all studied groups, GPT 1 type individuals showed the highest and GPT 2 type donors the lowest activity of the enzyme. Mean activity of GPT 1 type adults was 19.27 mU/ml, in GPT 2-1 adults 13.6 mU/ml and in GPT 2 adults 8.87 mU/ml. GPT 2 type activity corresponds to approximately 46% and GPT 2-1 type activity to, approximately, 71% activity of GPT 1 type. Independently of GPT type, activity of the enzyme was lower in women in whom it amounted to 71-83% activity detected in men. In children, alanine aminotransferase activity was higher than in adults about 15-29%.
mesh_terms: D000328:Adult; D000367:Age Factors; D000410:Alanine Transaminase / Q000097:blood* / Q000235:genetics; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010641:Phenotype; D011044:Poland; D012737:Sex Factors
chemical_list: D000410:Alanine Transaminase