title: A successful method of administering cyclosporin A to the chacma baboon.
abstract: Cyclosporin A (CYA) is a powerful immunosuppressant. Hitherto, it has proved difficult to maintain therapeutic whole-blood levels of the drug in the chacma baboon, making this animal unsuitable for transplantation studies if CYA is used. A successful method of maintaining adequate therapeutic levels after the intramuscular injection of CYA in a mixture of alcohol and Intralipid (Saphar) is described.
mesh_terms: D000284:Administration, Oral; D000818:Animals; D003524:Cyclosporins / Q000008:administration & dosage* / Q000097:blood; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D010215:Papio; D013997:Time Factors
chemical_list: D003524:Cyclosporins