Angiosarcoma arising in a patient with Maffucci syndrome.
Maffucci syndrome comprises multiple enchondromas together with cutaneous haemangiomas. Review of the literature shows a 15-20% incidence of sarcomatous change in one or more of the enchondromas. Malignancy arising from the vascular component, however, has only been reported in one case. We present a further case where a patient with Maffucci syndrome presented with multifocal angiosarcoma.
D003131:Combined Modality Therapy; D004687:Enchondromatosis / Q000473:pathology*; D005500:Follow-Up Studies; D005528:Foot; D006225:Hand; D006391:Hemangioma / Q000601:surgery; D006394:Hemangiosarcoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010009:Osteochondrodysplasias / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery