Effects of adhesion on mixing homogeneity. II: Highest attainable degree of mixing of a polydisperse ingredient and a monodisperse diluent.
The highest attainable degree of mixing of a polydisperse ingredient adherent to a monodisperse diluent was derived from the Poisson distribution and found to equal the quality of the noninteractive random mixture. The derivation assumes the arrangement of the ingredient particles onto the surface of the diluent to be random in the equilibrium situation. To produce ordered mixtures of a higher degree of homogeneity should require an ordering mechanism which must enforce the arrangement of the adherent particles to become ordered.
D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding; D005079:Excipients; D011336:Probability
D005079:Excipients