Persistent renal damage following pre-eclampsia: a renal biopsy study of 13 patients.
Renal biopsy material was examined from 13 patients who had a history of pre-eclampsia and who were biopsied after delivery. The characteristic 'endotheliosis' associated with pre-eclampsia appeared to resolve at varying rates and was not seen in biopsies taken more than 1 month after delivery. Four of the biopsies showed residual focal segmental glomerular lesions which are described. Focal global glomerular sclerosis (eight biopsies), focal interstitial scarring (seven biopsies) and arteriolo-sclerosis (nine biopsies) were also identified. These findings support those earlier reports which indicated that pre-eclampsia is capable of producing persistent renal damage in a small but significant percentage of cases.
D000293:Adolescent; D000328:Adult; D001161:Arteriosclerosis / Q000473:pathology; D001706:Biopsy; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D007668:Kidney / Q000276:immunology / Q000648:ultrastructure*; D007678:Kidney Glomerulus / Q000648:ultrastructure; D008854:Microscopy, Electron; D011225:Pre-Eclampsia / Q000276:immunology / Q000473:pathology*; D011247:Pregnancy
D007075:Immunoglobulin M