title: Antisera raised against the drug haloperidol.
abstract: Antisera against haloperidol coupled to albumin have been raised in two rabbits. Both antisera bind haloperidol with high affinity but differ in their selectivity for binding other substances. A sub-population of anti-haloperidol antibodies has been partially purified from one antiserum by affinity chromatography. This sub-population resembles the D2 dopamine receptor in its ability to bind some D2 receptor selective antagonists.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000302:isolation & purification; D005260:Female; D006220:Haloperidol / Q000276:immunology* / Q000378:metabolism; D007106:Immune Sera / Q000276:immunology*; D007114:Immunization; D011817:Rabbits; D011954:Receptors, Dopamine / Q000378:metabolism
chemical_list: D000906:Antibodies; D007106:Immune Sera; D011954:Receptors, Dopamine; D006220:Haloperidol