title: Molecular basis of the accumulation of abnormal proteins in progeria and aging fibroblasts.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D000595:Amino Acid Sequence; D002478:Cells, Cultured; D003470:Culture Media; D005347:Fibroblasts / Q000166:cytology; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000378:metabolism; D008875:Middle Aged; D008958:Models, Molecular; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism; D011371:Progeria / Q000378:metabolism*; D011487:Protein Conformation; D011506:Proteins / Q000378:metabolism*; D014305:Triose-Phosphate Isomerase / Q000378:metabolism; D014898:Werner Syndrome / Q000378:metabolism
chemical_list: D003470:Culture Media; D011506:Proteins; D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D007041:Hypoxanthine Phosphoribosyltransferase; D014305:Triose-Phosphate Isomerase