title: The proteins and RNAs specified by Clo Mor virus, a Scottish Nairovirus.
abstract: The proteins and RNAs of Clo Mor virus have been analysed. Virus-specific proteins in infected cells had previously been identified by isotopic labelling and radioimmunoprecipitation; these were three glycoproteins (mol. wt. 115K, 90K and 80K) and an unglycosylated nucleocapsid (N) protein (50K). We have performed pulse-chase experiments which indicated that the 115K protein is processed to give the 90K and 80K proteins, while a 45K protein was detected in released virions after prolonged chase. Translation in vitro of mRNA extracted from Clo Mor virus-infected cells resolved only the N protein. Three species of RNA were extracted from Clo Mor virus intracellular nucleocapsids and have been designated L (11000 to 13000 bases), M (6300 bases) and S (1900 bases). The processing of viral proteins and the sizes of RNAs are characteristic of the Nairovirus genus of the family Bunyaviridae.
mesh_terms: D002043:Bunyaviridae / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D002213:Capsid / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics; D006023:Glycoproteins / Q000032:analysis / Q000235:genetics; D008970:Molecular Weight; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000235:genetics; D012367:RNA, Viral / Q000032:analysis* / Q000235:genetics; D014758:Viral Core Proteins / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics; D014764:Viral Proteins / Q000032:analysis* / Q000096:biosynthesis / Q000235:genetics
chemical_list: D006023:Glycoproteins; D012333:RNA, Messenger; D012367:RNA, Viral; D014758:Viral Core Proteins; D014764:Viral Proteins