title: [Changes in the adrenal medulla of the rat during immobilization stress].
abstract: A combined histofluorescent, light optic and electron microscopic investigation has been performed to study the medulla of the adrenals in intact rats (August strain) and immediately after immobilization for 30 h and 24 h after. In the intact animals heteromorphism of the medulla is demonstrated; this depends on the fact that adrenocytes are at different stages of the secretory cycle. Immobilization for 30 h results in synchronization of secretion; this is determined by adaptation of the adrenal system to immobilization. One day after immobilization restoration of heteromorphism in chromaffinocytes is demonstrated. The changes described are compensatory-adaptive reactions of the adrenal medulla to the stress in the animals survived.
mesh_terms: D000313:Adrenal Medulla / Q000378:metabolism / Q000473:pathology*; D000818:Animals; D002395:Catecholamines / Q000378:metabolism*; D003594:Cytoplasmic Granules / Q000378:metabolism; D006651:Histocytochemistry; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000378:metabolism / Q000473:pathology*
chemical_list: D002395:Catecholamines
vernacular_title: Izmeneniia mozgovogo veshchestva nadpochechnika krysy pri immobilizatsionnom stresse.