title: Diverticulosis in total colonic aganglionosis.
abstract: Two infants with total colonic aganglionosis (TCA) extending into the distal part of the ileum are described. Considerable diagnostic delay occurred with the correct diagnosis established first at 3 and 8 months, respectively. Radiologic findings compatible with TCA such as prolonged barium retention, reflux into ileum following barium enema, and foreshortening of colon were not clearly evident initially. Both patients demonstrated multiple acquired colon diverticula which increased both in number and size during the period of observation. These diverticula are probably a late manifestation of the spastic state of the anganglionic colon. Thus demonstration of diverticula supplies a strong evidence of TCA in infants with intestinal obstruction.
mesh_terms: D001466:Barium Sulfate; D004239:Diverticulitis, Colonic / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D004733:Enema; D006801:Humans; D007077:Ileal Diseases / Q000000981:diagnostic imaging; D007223:Infant; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging; D008297:Male; D008531:Megacolon / Q000150:complications / Q000000981:diagnostic imaging*; D011859:Radiography
chemical_list: D001466:Barium Sulfate