A case history of myopathic carnitine deficiency benefited by glucocorticoids and L-carnitine supplementation.
While the term "drug-nutrient interactions" tends to conjure up a concept of an adverse combination, such as anticonvulsants impairing folate metabolism or alcohol blocking active thiamine absorption, there are situations in which a drug and nutrient can act in a complementary manner, to correct a metabolic defect. This case history illustrates such a positive interaction of glucocorticoids and L-carnitine supplements improving muscle function in a patient with myopathic carnitine deficiency.
D000328:Adult; D002331:Carnitine / Q000172:deficiency* / Q000378:metabolism / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000032:analysis; D009135:Muscular Diseases / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism*; D011241:Prednisone / Q000627:therapeutic use*
D002331:Carnitine; D011241:Prednisone