Radiation-induced coronary obstructive atherosclerosis and sudden death in a teenager.
An 18-year-old woman, affected by Hodgkin's disease and treated successfully with radiotherapy, died suddenly. The postmortem study showed an acute septal myocardial infarction in the presence of a severe focal atherosclerotic lesion of the anterior descending coronary artery. This suggests that radiation may contribute to the early development of coronary artery disease.
D000293:Adolescent; D003131:Combined Modality Therapy; D003327:Coronary Disease / Q000473:pathology*; D003331:Coronary Vessels / Q000473:pathology / Q000528:radiation effects*; D003645:Death, Sudden / Q000473:pathology*; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D009206:Myocardium / Q000473:pathology; D011832:Radiation Injuries / Q000473:pathology*; D011879:Radiotherapy Dosage