title: Lower extremity arterial disease in young adults. A systematic approach to early diagnosis.
abstract: General and vascular surgeons are consulted occasionally to evaluate young adults with ischemia of the lower extremity. Between 1975 and 1985, 51 adults under 40 years of age who had arterial occlusive disease of the lower limb were managed. Although premature atherosclerosis was the most common problem (50%), claudication or limb-threatening ischemia also resulted from other sources (thromboembolism, popliteal artery entrapment, Buerger's disease, collagen vascular disease, and Takayasu's arteritis). Identifying the exact cause was sometimes difficult. The authors were impressed with the number of young adults who had delay in diagnosis and treatment (30 patients, 59%) before referral for a surgical opinion. In this paper, the attempt has been made to uncover the reasons for delayed diagnosis and to suggest a systematic approach that should lead to early recognition of lower extremity ischemia in this age group.
mesh_terms: D000293:Adolescent; D000328:Adult; D001157:Arterial Occlusive Diseases / Q000175:diagnosis* / Q000209:etiology; D001161:Arteriosclerosis / Q000150:complications / Q000175:diagnosis; D004617:Embolism / Q000150:complications / Q000175:diagnosis; D005260:Female; D005534:Foot Diseases / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007383:Intermittent Claudication / Q000150:complications / Q000175:diagnosis; D007511:Ischemia / Q000175:diagnosis* / Q000209:etiology; D007866:Leg / Q000098:blood supply*; D008297:Male; D010146:Pain / Q000150:complications / Q000175:diagnosis; D012146:Rest; D013923:Thromboembolism / Q000150:complications / Q000175:diagnosis; D014034:Toes / Q000098:blood supply; D014456:Ulcer / Q000150:complications / Q000175:diagnosis