title: Occurrence of haploid and haploid/diploid mosaic embryos in untreated and androstenedione-immune Australian Merino sheep.
abstract: Chromosome counts were obtained from 73 out of 177 (41%) early cleavage-stage Merino embryos. A further 13 embryos were classified as probably diploid. Chromosome aberrations were found in 8 (11%) embryos, one of which was aneuploid and the remainder (9.6%) had euploid abnormalities. If the probable diploid embryos are included, the incidence of euploid aberrations falls to 8.1%. Of the abnormal embryos there was one aneuploid with 2N = 55, two haploids, four haploid/diploid mosaics and one zygote with 4 haploid metaphase plates. Two additional zygotes had 4 interphase pronuclei. Four of the euploid abnormalities were attributable to the entry of two or more spermatozoa and therefore polyspermy is the largest single factor leading to chromosomally aberrant embryos in this population of Merino ewes.
mesh_terms: D000735:Androstenedione / Q000276:immunology; D000818:Animals; D002875:Chromosomes; D002970:Cleavage Stage, Ovum / Q000502:physiology*; D004171:Diploidy; D005260:Female; D006238:Haploidy; D009030:Mosaicism; D011003:Ploidies; D012756:Sheep / Q000235:genetics* / Q000276:immunology
chemical_list: D000735:Androstenedione