Relative biological effectiveness of 125I in the induction of micronuclei in human peripheral blood lymphocytes.
The RBE for 125I relative to 30 keV X-rays, 4 MeV X-rays and 137Cs gamma rays was determined using the induction of micronuclei in human lymphocytes as the biological test system. The 125I photons were as effective as the 30 keV X-rays. If a micronuclei count of 50 per 1500 cells is used as the endpoint, the RBE for 125I was found to be about 1.8 and 1.6 when 4 MeV X-rays and 137Cs gamma rays were used as the reference radiation, respectively.
D001918:Brachytherapy; D002467:Cell Nucleus / Q000528:radiation effects; D002470:Cell Survival; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D066298:In Vitro Techniques; D007457:Iodine Radioisotopes; D008214:Lymphocytes / Q000528:radiation effects* / Q000648:ultrastructure; D012062:Relative Biological Effectiveness
D007457:Iodine Radioisotopes