title: Experimental study of physiological pulsatile flow past valve prosthesis in a model of human aorta--II. Tilting disc valves and the effect of orientation.
abstract: In Part II of this two paper sequence, pulsatile flow development past a tilting disc valve in a model human aorta has been studied using quantitative laser Doppler techniques. The valve was mounted in three different orientations with respect to the aortic root in this study. Under pulsatile flow, the region of flow reversal induced near the wall of the minor flow orifice extends to more than one tissue annulus diameter downstream from the valve into the ascending aorta. In a plane perpendicular to the tilt axis, a bi-helical secondary flow is induced distal to the valve. This secondary flow is further compounded by the multiple curvatures in the aorta. Hence the valve orientation affects the velocity profiles as far downstream as the mid-arch region as well as in the brachio-cephalic arterial branch. In the mid-arch region, a flow reversal along the entire cross-section is observed in early diastole for all the three orientations of the disc valve.
mesh_terms: D001011:Aorta / Q000502:physiology*; D001021:Aortic Valve / Q000502:physiology*; D001783:Blood Flow Velocity; D004867:Equipment Design; D006350:Heart Valve Prosthesis; D006801:Humans; D007834:Lasers; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D011674:Pulse; D014465:Ultrasonics