Cross-reaction of a monoclonal antibody with fibroblasts from marsupials of the Macropodidae and Tarsipedidae families.
A monoclonal antibody, GA-1, was prepared against an M. rufogriseus cell surface antigen on an M. rufogriseus (red necked wallaby)--mouse somatic cell hybrid. Fibroblasts from a number of marsupial species were tested for reaction with GA-1, and only those from the Macropodidae species and the sole member of the family Tarsipedidae reacted, indicating that the Tarsipedidae is possibly more closely related to the Macropodidae than to any other group of marsupials examined.
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D000954:Antigens, Surface / Q000276:immunology; D002875:Chromosomes / Q000276:immunology*; D005260:Female; D005347:Fibroblasts / Q000276:immunology / Q000648:ultrastructure; D006825:Hybridomas / Q000276:immunology; D008214:Lymphocytes / Q000648:ultrastructure; D008297:Male; D008394:Marsupialia / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013045:Species Specificity
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface