Membrane plasmapheresis technique in rats. Confirmation of antibody rebound.
A simple continuous flow method is described that transfers hollow fiber membrane plasmapheresis technology to rats. The technique is applied in an experimental approach that confirms the existence of a distinct overshooting antibody rebound mechanism after plasma exchange. Anti-SRBC antibody levels exceeded the baseline within 48 h and reached their maximum during the first 2 weeks after exchange.
D000818:Animals; D000917:Antibody Formation; D007700:Kinetics; D010956:Plasmapheresis / Q000295:instrumentation / Q000379:methods*; D051381:Rats