title: Human assay for identifying substances which induce non-allergic contact urticaria: the NICU-test.
abstract: The problems of non-immunologic contact urticariogens are addressed from various points of view. A new test for evaluating substances which may cause non-immunologic contact urticaria in humans, the NICU test, is introduced. Characteristic data of widely known contact urticariogens are given.
mesh_terms: D000171:Acrolein / Q000009:adverse effects / Q000031:analogs & derivatives; D000328:Adult; D001565:Benzoates / Q000009:adverse effects; D019817:Benzoic Acid; D004121:Dimethyl Sulfoxide / Q000009:adverse effects; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005260:Female; D005557:Formaldehyde / Q000009:adverse effects; D006801:Humans; D008297:Male; D008954:Models, Biological; D012621:Seasons; D012882:Skin Tests / Q000379:methods*; D013011:Sorbic Acid / Q000009:adverse effects; D014581:Urticaria / Q000139:chemically induced* / Q000175:diagnosis
chemical_list: D001565:Benzoates; D005557:Formaldehyde; D000171:Acrolein; D019817:Benzoic Acid; C012843:cinnamaldehyde; D013011:Sorbic Acid; D004121:Dimethyl Sulfoxide