N-acetyltransferase phenotypes in bladder tumour patients with and without carcinoma in situ in selected site biopsies.
The N-acetyltransferase phenotypes were revealed among 32 patients with bladder tumour and concurrent carcinoma in situ peripherally in the bladder mucosa. Fifty-nine per cent of the bladder tumour patients with concurrent carcinoma in situ were slow acetylator phenotypes in contrast to 68% of 28 bladder tumour patients with normal histological specimens peripherally in the bladder mucosa. This points to a lack of industrial arylamine bladder tumour cases in Denmark.
D000123:Acetyltransferases / Q000235:genetics*; D001191:Arylamine N-Acetyltransferase / Q000235:genetics*; D001706:Biopsy; D002278:Carcinoma in Situ / Q000201:enzymology* / Q000473:pathology; D006801:Humans; D009092:Mucous Membrane / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000201:enzymology* / Q000473:pathology; D010641:Phenotype; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000201:enzymology* / Q000473:pathology
D000123:Acetyltransferases; D001191:Arylamine N-Acetyltransferase