Early and predominant respiratory muscle involvement in motor neurone disease.
We report a 61 year old man with motor neurone disease who presented with dyspnoea and ventilatory failure when the limb and bulbar muscles were relatively spared. This unusual pattern of predominant respiratory muscle involvement persisted throughout the twenty-one month course of his illness.
D004417:Dyspnea / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons; D009468:Neuromuscular Diseases / Q000150:complications / Q000175:diagnosis*; D012129:Respiratory Function Tests; D012131:Respiratory Insufficiency / Q000209:etiology