Intravaginal application of leukocyte interferon gel in the treatment of cervical intraepithelial neoplasia (CIN).
Leukocyte interferon gel (1 X 10(6) units) was applied twice daily by a vaginal applicator to areas of cervical intraepithelial neoplasia (CIN) in 7 patients. A partial response was obtained in 3 patients and complete response in 2 patients. This suggests that leukocyte interferon gel can be used to treat CIN.
D000287:Administration, Topical; D000328:Adult; D002277:Carcinoma / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000008:administration & dosage*; D002578:Uterine Cervical Dysplasia / Q000188:drug therapy / Q000276:immunology; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000276:immunology
D007370:Interferon Type I