title: The effect of flexor sheath integrity on nutrient uptake by chicken flexor tendons.
abstract: The effect of varying degrees of flexor sheath integrity (sheath excised, incised, or incised and repaired) on the uptake of 3H-proline by chicken flexor tendons in Zone II was studied. The tendons were either: normal and uninjured, lacerated and repaired, or uninjured except for vinculum longum ligation. Different degrees of sheath integrity did not influence the uptake of 3H-proline by the tendons. The tendon does not appear to be dependent on a synovial environment for nutrients and is capable of obtaining these nutrients by diffusion from the surrounding extracellular tissue fluid. Diffusion is the primary nutrient pathway to the flexor tendon in this area, because removing its major vascular attachment (i.e., the vinculum longum) did not effect proline uptake. Careful closure of the sheath with restoration of a synovial environment does not appear to be necessary for tendon nutrition.
mesh_terms: D000818:Animals; D002645:Chickens; D005260:Female; D011392:Proline / Q000378:metabolism*; D013708:Tendon Injuries / Q000378:metabolism; D013710:Tendons / Q000378:metabolism* / Q000601:surgery; D014316:Tritium; D014945:Wound Healing
chemical_list: D014316:Tritium; D011392:Proline