title: Pressure studies of the ileocecal sphincter after small bowel resection in rabbits.
abstract: The function of the ileocecal sphincter (ICS) in rabbits was investigated after extensive small bowel resection. The reflux pressure in anterograde (P1) and retrograde (P2) direction was measured before, 7 days after, and 1 year after small bowel resection, nd compared with a group of rabbits in which a bypass-operation of the same length of the small bowel had been performed. After 7 days, both P1 and P2 showed a marked decrease in the resection group. One year after the operation, pressures had increased again but were still lower than before the resection. Significantly minor pressure changes were found 7 days after bypass surgery. We consider that ICS-insufficiency can be one cause of the features of short bowel syndrome.
mesh_terms: D000818:Animals; D005260:Female; D007080:Ileocecal Valve / Q000503:physiopathology*; D007421:Intestine, Small / Q000601:surgery*; D008297:Male; D011312:Pressure; D011817:Rabbits; D012778:Short Bowel Syndrome / Q000209:etiology / Q000503:physiopathology; D013997:Time Factors