Effect of xylazine and ketamine on intraocular pressure in horses.
Intraocular pressure was measured with a MacKay-Marg tonometer in eight horses following auriculopalpebral nerve block and topical application of lignocaine. Measurements were recorded before and after xylazine, 1.1 mg/kg intravenously, every two minutes for 16 minutes after administration of ketamine, 2.2 mg/kg intravenously, and after recovery from anaesthesia. Before xylazine, intraocular pressure was 17.1 +/- 3.9 and 18.4 +/- 2.2 mm Hg in the left and right eyes, respectively. Intraocular pressure tended to decrease after administration of xylazine and ketamine, with a significant decrease in one eye six minutes after injection of ketamine.
D000818:Animals; D006736:Horses / Q000502:physiology*; D007429:Intraocular Pressure / Q000187:drug effects*; D007649:Ketamine / Q000494:pharmacology*; D008297:Male; D013843:Thiazines / Q000494:pharmacology*; D014991:Xylazine / Q000494:pharmacology*
D013843:Thiazines; D014991:Xylazine; D007649:Ketamine