Significance of acquired nonrandom 7/14 translocations.
We have detected eight patients with a single metaphase having a 7/14 translocation. In all cases, the breakpoint on chromosome 14 was 14q12, while the breakpoint on chromosome 7 was 7q35 in three cases and 7p13 in five cases. The factors that may be involved in these nonrandom translocations are discussed.
D000328:Adult; D001260:Ataxia Telangiectasia / Q000235:genetics; D002675:Child, Preschool; D002901:Chromosomes, Human, 13-15; D002906:Chromosomes, Human, 6-12 and X; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009857:Oncogenes; D011948:Receptors, Antigen, T-Cell / Q000235:genetics; D014178:Translocation, Genetic
D011948:Receptors, Antigen, T-Cell