title: Gastric emptying of liquids in the dog: serial test meal and modified emptying-time techniques.
abstract: A serial test meal technique was used in the dog to evaluate the gastric emptying of a liquid test meal. On separate days, a phenol red test meal was placed in the stomach and completely aspirated at different times. A composite representation of the gastric emptying pattern was obtained for each dog, and a set of normative data was generated. Three emptying determinants (emptying time, half-life, and starting index) were calculated. The basic pattern of canine gastric emptying was linear and declined exponentially or as a function of the square root of the gastric volume. A modified emptying-time technique (METT) correlated well with the serial test meal and a set of normative values was determined. The METT was performed by aspirating test meal from the stomach 30 minutes after instillation. The METT was a simple and inexpensive technique that could be performed in 1 short testing period. With the METT, the half-life of gastric emptying was calculated, using the log of the percentage of retention of test meal; gastric emptying time was calculated, using the square root of the percentage of retention of test meal. Acetylpromazine was shown not to alter gastric emptying of a liquid test meal.
mesh_terms: D000821:Animal Feed; D000818:Animals; D004285:Dogs / Q000502:physiology*; D005746:Gastric Emptying; D005753:Gastric Mucosa / Q000378:metabolism; D006207:Half-Life; D007441:Intubation, Gastrointestinal / Q000662:veterinary; D010637:Phenolsulfonphthalein; D013270:Stomach / Q000502:physiology*; D013997:Time Factors
chemical_list: D010637:Phenolsulfonphthalein