Idiopathic corneal endotheliopathy. A report of two cases.
Two male patients had corneal endotheliopathy of unknown origin. In both patients it was characterized by continuously progressing bullous keratopathy preceded by a line of keratic precipitates resembling a rejection line. The disease was progressive and did not respond to intensive corticosteroid therapy. No virus could be isolated from the aqueous humor, and the aqueous-antibody titers to herpes simplex, varicella zoster, and measles viruses were below detection level.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D001327:Autoimmune Diseases / Q000473:pathology; D003315:Cornea / Q000473:pathology; D003316:Corneal Diseases / Q000188:drug therapy / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D004487:Edema / Q000188:drug therapy / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D004727:Endothelium / Q000473:pathology; D006801:Humans; D008297:Male; D014777:Virus Diseases / Q000150:complications / Q000276:immunology
D000305:Adrenal Cortex Hormones; D000914:Antibodies, Viral