title: [Specific safety and immunogenicity of a subunit vaccine against hepatitis B].
abstract: The results of trials of a subunit vaccine against hepatitis B in volunteers are presented. The active substance of the vaccine was HBsAg isolated from the plasma of asymptomatic antigen carriers. The preparation under study is highly immunogenic, shows poor reactogenicity, and safety in use.
mesh_terms: D000328:Adult; D004341:Drug Evaluation; D006509:Hepatitis B / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000008:administration & dosage / Q000009:adverse effects / Q000276:immunology; D006801:Humans; D007117:Immunization, Secondary; D008297:Male; D011863:Radioimmunoassay; D013997:Time Factors; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology
chemical_list: D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D014761:Viral Hepatitis Vaccines
vernacular_title: Izuchenie spetsificheskoĭ bezvrednosti i immunogennosti sub"edinichnoĭ vaktsiny protiv gepatita B.