The clearance of Xenon-133 following its parenchymal injection: a rapid method for estimating functional liver blood-flow.
Portal venous flow, total hepatic blood-flow and hepatic artery flow were measured in healthy dogs by electromagnetic flowmetry and a double indicator dilution technique. Functional liver blood-flow was measured by the double indicator dilution technique. Functional hepatic blood-flow did not correlate with portal venous flow, total hepatic blood-flow or hepatic artery flow, measured by either electromagnetic flowmetry or a double indicator dilution technique. There was a good correlation (r = 0.83, P less than 0.001) between functional hepatic blood-flow and liver blood-flow, measured by the clearance of Xenon-133 injected directly into the liver parenchyma. It is concluded that the clearance of Xenon-133, injected directly into the liver parenchyma, is a rapid and simple method for measuring functional hepatic blood-flow.
D000818:Animals; D004285:Dogs; D006499:Hepatic Artery / Q000000981:diagnostic imaging*; D007700:Kinetics; D008099:Liver / Q000000981:diagnostic imaging; D008102:Liver Circulation; D008111:Liver Function Tests; D011169:Portal Vein / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012039:Regional Blood Flow; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes