Moist heat inactivation of Cryptosporidium sp.
Cryptosporidia that were infective for infant mice were subjected to various moist heat treatments and subsequently tested in infant mice for infectivity. Warming from 9 degrees C to 55 degrees C over a period of 15 to 20 minutes neutralized infectivity in calf feces, cecal contents, and ileal scrapings. Inocula held at 45 degrees C for 5 to 20 minutes lost its infectivity. These results suggest that pasteurization of raw milk, circumstantially incriminated in cryptosporidial transmission, would neutralize cryptosporidial infectivity.
D000818:Animals; D000831:Animals, Newborn; D002417:Cattle; D002418:Cattle Diseases / Q000469:parasitology; D003457:Cryptosporidiosis / Q000469:parasitology; D003458:Cryptosporidium / Q000472:pathogenicity; D006358:Hot Temperature; D006813:Humidity; D007411:Intestinal Diseases, Parasitic / Q000469:parasitology; D051379:Mice; D008892:Milk