Selection, follow-up, and analysis in the Coke Oven Study.
The current standard for exposure to coke oven emissions sets a permissible exposure of 150 micrograms benzene-soluble fraction of total particulate matter/m3. The major epidemiologic study that formed the basis for this standard including a review of the evidence of a dose-response relationship between exposure to coal tar pitch volatiles and lung cancer is reviewed. Particular attention was given to the selection of the cohort, follow-up procedures, and the evolution of the analysis.
D003031:Coal; D003033:Coal Tar; D003077:Coke; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality*; D008297:Male; D008452:Maximum Allowable Concentration; D008669:Metallurgy; D009784:Occupational Diseases / Q000401:mortality*; D011446:Prospective Studies; D012142:Respiratory Tract Neoplasms / Q000401:mortality; D013223:Statistics as Topic
D003031:Coal; D003077:Coke; D003033:Coal Tar