Postnatal development of the anulospiral endings of Ia fibers in muscle spindles of mice.
The formation of the anulospiral ending of Ia fibers in muscle spindles was investigated in the masseter muscle of developing mice. Before 15 days after birth, the complete anulospiral ending was not observed in almost all of the muscle spindles examined. With the growth of mice, the Ia fiber began to construct the spiral ending, and by the 40th postnatal day after weaning, almost all of the Ia fibers of the muscle spindles had complete coiled endings, though the formation still continued in some spindles. The continuous formation of anulospiral endings for a long period after weaning indicates that muscle spindle morphogenesis may be affected by muscle tension in the masseter muscle due to the movement activated after weaning.
D000818:Animals; D008409:Mastication; D008465:Mechanoreceptors / Q000033:anatomy & histology / Q000254:growth & development*; D051379:Mice; D024510:Muscle Development; D009132:Muscles / Q000201:enzymology; D009469:Neuromuscular Junction / Q000033:anatomy & histology / Q000254:growth & development*; D013385:Succinate Dehydrogenase / Q000378:metabolism
D013385:Succinate Dehydrogenase