title: Is serum selenium a risk factor for cancer?
abstract: A narrow band of counties extending along the southeastern Atlantic coast from Jacksonville, Florida to Charleston, South Carolina were found to have excessively high incidence rates for esophageal cancer in non-white males. White males in the same areas have a 30% higher incidence rate for lung cancer but only average incidence rates were found for non-white males. Selenium is considered to decrease cancer risk in the animal model. In this coastal region, a study of 130 cancer patients who developed a malignancy 2-12 years after baseline examination showed no dose response relationship between baseline serum selenium levels and risk of subsequent cancer.
mesh_terms: D044383:Black People; D004938:Esophageal Neoplasms / Q000209:etiology*; D005260:Female; D005843:Geography; D005845:Georgia; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000453:epidemiology / Q000209:etiology*; D012016:Reference Values; D012306:Risk; D012424:Rural Population; D012643:Selenium / Q000097:blood*; D012737:Sex Factors; D044465:White People; D001741:Black or African American
chemical_list: D012643:Selenium