[Experimental staphylococcal sepsis].
Experimental staphylococcal sepsis has been examined in the model suggested by the authors. Staphylococcus aureus culture in a 10% CaCl2 solution was injected intramuscularly to 230 adult albino rats. Fundamental signs of sepsis have been revealed: increased mortality (up to 28% in rats weighing 120-140 g) from day 1 to day 45 after infection, development of local infectious foci, bacteremia, septicemia and septicopyemia. The authors describe severe dystrophic changes in septic emboli and bacterial colonies in different organs.
D000818:Animals; D007678:Kidney Glomerulus / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male; D051381:Rats; D013154:Spleen / Q000473:pathology; D013203:Staphylococcal Infections / Q000401:mortality / Q000473:pathology*
Izuchenie éksperimental'nogo stafilokokkovogo sepsisa.