Renal encephalopathy in a cow.
A 14-month-old Holstein heifer collapsed suddenly and died. Significant gross post mortem findings were limited to the kidneys. Histopathological examination revealed a severe, chronic, diffuse, interstitial nephritis. Microscopic examination of the brain revealed a multifocal spongiform encephalopathy, closely resembling that seen in cattle with hepatic encephalopathy. As is well recognized in man, this is a case of encephalopathy resulting from renal failure.
D058186:Acute Kidney Injury / Q000150:complications / Q000662:veterinary*; D000818:Animals; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000209:etiology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology*; D005260:Female; D007668:Kidney / Q000473:pathology