title: The effect of increased respiratory resistance on glycogen and triglyceride levels in the respiratory muscles of the rat.
abstract: The effect of increased respiratory resistance (stenosis of the trachea) on glycogen and triglyceride levels in the diaphragm (D) and intercostal (external-IE, internal-II) muscles was studied in the rat. Tracheal stenosis resulted in a reduction of glycogen level in the muscles. For the fed rats the reductions were: D-45 and 79%, IE-14 and 30%, II-14 and 35%, 0.5 and 3 h after stenosis, respectively. For rats fasted for 24 h the reductions were: D-64 and 86%, IE-33 and 71%, II-40 and 82%, after 0.5 and 3 h respectively. The level of triglycerides in the muscles was stable during stenosis in the fed group, whereas in the fasted group it were reduced in the diaphragm by 50% after 0.5 h, and by 52% after 3 h. It is concluded that both endogenous and blood-born energy fuels are utilized by the respiratory muscles during increased resistance breathing.
mesh_terms: D000402:Airway Obstruction; D000818:Animals; D003964:Diaphragm / Q000378:metabolism*; D005215:Fasting; D006003:Glycogen / Q000378:metabolism*; D007366:Intercostal Muscles / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012119:Respiration; D014132:Trachea / Q000502:physiology; D014280:Triglycerides / Q000378:metabolism*
chemical_list: D014280:Triglycerides; D006003:Glycogen