A method for determining threshold from single-unit neural activity.
A computationally straightforward method is described for determining the latency, duration and magnitude of stimulus-evoked single-unit neural activity. A unique feature of the method is its ability to define the neural response without reference to stimulus parameters. First, the temporal component of the spike train that represents the response is located and then that component is analyzed to determine the magnitude of the response. Intensity-response functions can then be constructed, using the number of extra spikes above baseline activity as a measure of response magnitude. Threshold can be defined as any point on the intensity-response function.
D000200:Action Potentials; D000818:Animals; D003623:Dark Adaptation; D004594:Electrophysiology / Q000379:methods*; D006054:Goldfish / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D009482:Neurophysiology / Q000379:methods*; D010812:Physical Stimulation; D012165:Retinal Ganglion Cells / Q000502:physiology