title: Effect of pinealectomy on serum melatonin, luteinizing hormone and prolactin: a case report.
abstract: A patient, aged 47 is described in whom changes in hormonal profiles were observed following surgical excision of the pineal. She presented with a clinical syndrome of increased intracranial pressure and postmenopausal symptoms. Computerized tomographic scans showed obstructive hydrocephalus from a cystic lesion in the pineal region. Surgical removal of the cystic mass revealed a benign ependymal cyst and normal pineal tissue. After the operation, she had no nocturnal increase in serum melatonin. The morning basal LH was further elevated and night-time PRL showed little fluctuation from the basal levels.
mesh_terms: D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000097:blood / Q000503:physiopathology* / Q000601:surgery; D007986:Luteinizing Hormone / Q000097:blood*; D008550:Melatonin / Q000097:blood*; D008875:Middle Aged; D010870:Pineal Gland / Q000503:physiopathology* / Q000601:surgery; D011388:Prolactin / Q000097:blood*
chemical_list: D011388:Prolactin; D007986:Luteinizing Hormone; D008550:Melatonin