title: [Reliability of automatic blood coagulometer (KC-10) on some species of experimental animals].
abstract: Prothrombin time, activated partial thromboplastin time and fibrinogen determinations of some species of experimental animals with automatic coagulometer KC-10 were examined in regard to reliability and usefulness. In the examinations of within-run precision of the undiluted and diluted plasma of dog, rabbit and rat, the results were acceptable. In the examinations of capability detecting N-nitrosodimethylamine-induce coagulopathy of rats, the results were found to be accurate. The comparison studies between KC-10 and the reference instrument AUTO-FI indicated good correlations. These results supported the reliability and usefulness of use of automatic coagulometer for blood coagulability test on experimental animals.
mesh_terms: D000818:Animals; D000830:Animals, Laboratory / Q000097:blood*; D001777:Blood Coagulation; D001780:Blood Coagulation Tests / Q000295:instrumentation* / Q000592:standards; D004128:Dimethylnitrosamine / Q000633:toxicity; D004285:Dogs; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D010314:Partial Thromboplastin Time; D011517:Prothrombin Time; D011817:Rabbits; D051381:Rats
chemical_list: D005340:Fibrinogen; D004128:Dimethylnitrosamine