[Myocardial morphology in endotoxic shock].
The myocardium of rabbits with endotoxin shock produced by two intravenous injections (0.1 and 0.3 mg/kg) of the typhoid fever bacillus antigen was studied histologically, histochemically, histoenzymatically and by polarization microscopy. Animals were killed by decapitation 0,5-1,5, 5-10, 24-30, 48-80, 120-194 hours after the 2nd injection; animals dying in the course of experiment were also examined. Morphological substrate of heart insufficiency, morphofunctional heterogeneity of cardiomyocytes of both inner and external myocardial layers were revealed. Hypoxia of a complex origin is the main cause of the above alterations.
D000818:Animals; D002449:Cell Aggregation; D004727:Endothelium / Q000473:pathology; D004734:Energy Metabolism; D006651:Histocytochemistry; D008833:Microcirculation / Q000473:pathology; D009200:Myocardial Contraction; D009206:Myocardium / Q000201:enzymology / Q000473:pathology*; D009504:Neutrophils / Q000473:pathology; D011817:Rabbits; D012772:Shock, Septic / Q000201:enzymology / Q000473:pathology*; D013997:Time Factors
Morfologiia miokarda pri éndotoksicheskom shoke.