title: [Use of high doses of glucocorticoids in patients with rheumatic diseases].
abstract: Short-term application of high doses of glucocorticoids removes the acuity of the generalized patterns of systemic rheumatic diseases. This is documented by the reported data and analysis of the authors' own 15 observations. The dose of glucocorticoids, duration of their application and administration routes are determined by the degree of the pathological process activity and by the organs concerned (kidneys, central nervous system). If the effect attained is doubtful, repeated courses of intensive treatment with glucocorticoids are indicated in some cases.
mesh_terms: D000208:Acute Disease; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D003882:Dermatomyositis / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage*; D012008:Recurrence; D013997:Time Factors
chemical_list: D011239:Prednisolone; D008775:Methylprednisolone
vernacular_title: Primenenie vysokikh doz gliukokortikoidov u bol'nykh s revmaticheskimi zabolevaniiami.