title: Methodologies to produce and assess standardized trauma to the skin.
abstract: In order to learn how mechanical trauma affects the skin, it is necessary to establish quantitative relationships between the degree of trauma and the extent of the biological response. This requires the development of novel techniques and instrumentation. In this paper, two new techniques for applying standardized increments of trauma to the skin are presented. Methods for measuring the effects on the skin surface and on skin function are described.
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012107:Research Design; D012867:Skin / Q000293:injuries*; D012879:Skin Physiological Phenomena; D013314:Stress, Mechanical; D014867:Water / Q000502:physiology
chemical_list: D014867:Water