title: Arterial blood gases fail to reflect acid-base status during cardiopulmonary resuscitation: a preliminary report.
abstract: The American Heart Association's current standards for CPR indicate that acid-base therapy should be guided by measurements of arterial blood gases. However, we have discovered a striking discrepancy between arterial and venous blood gases during CPR: severe venous hypercarbia and acidosis may coexist with simultaneous arterial alkalosis. Arterial blood gases during CPR, therefore, may not accurately reflect the acid-base status of mixed venous blood and thus may fail to indicate systemic acid-base status.
mesh_terms: D000136:Acid-Base Equilibrium; D000818:Animals; D001158:Arteries; D001784:Blood Gas Analysis; D006323:Heart Arrest / Q000097:blood* / Q000628:therapy; D012151:Resuscitation; D013552:Swine; D014680:Veins