[Extremely low oncotic pressure in postpartum eclampsia].
In a primigravida of 25 years of age who had an attack of eclampsia seven hours after Caesarean section we found an abnormally low oncotic pressure (i.e. colloid osmotic pressure, COP) in the plasma, namely, 14.5 mm Hg instead of the normal value which is greater than 20mm Hg. In EPH-gestosis there is a pathogenetic dependence of the oedemas, hypovolaemia, haemoconcentration and insufficient perfusion of parenchymatous organs, on the transcapillary colloid osmotic pressure gradient. As a result of colloid substitution with human albumin (20-40 g per day) effected with oncometric control, the COP increased stepwise to 18.3 mm Hg within one week and the distribution of fluid between the intravascular and extravascular space normalised. Repeated direct measurement of the colloid osmotic pressure (in our case by Onkometer BMT 921, Thomae) proved extremely helpful especially as a means of therapy control.
D000328:Adult; D000418:Albumins / Q000008:administration & dosage; D002585:Cesarean Section; D003102:Colloids; D004461:Eclampsia / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009997:Osmotic Pressure; D011247:Pregnancy; D011644:Puerperal Disorders / Q000503:physiopathology / Q000628:therapy
D000418:Albumins; D003102:Colloids
Extreme Hyponkose bei postpartaler Eklampsie.