Reproducibility of metabolical parameters during successive coronary sinus pacing in patients known to have coronary artery disease.
We have studied the reproducibility of myocardial extraction ratios of lactate, glucose and free fatty acids in patients with stable angina during atrial pacing. Two pacing periods, separated by an interval of 45 min, were imposed. The individual data were highly reproducible for lactate. Mean values for glucose and for free fatty acids were closely similar in the two successive tests, but the individual response was not so highly reproducible. We recommend the demonstration of the reproducibility of events during pacing in studies in which the effects of the therapeutic interventions are being assessed. This is especially so when observations are made in a small number of patients.
D000787:Angina Pectoris / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002304:Cardiac Pacing, Artificial; D003327:Coronary Disease / Q000097:blood*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006439:Hemodynamics; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D009206:Myocardium / Q000378:metabolism
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007773:Lactates; D019344:Lactic Acid