title: Candida albicans tenosynovitis of the hand.
abstract: Invasive fungal infections of the hand are extremely rare and usually require an immunocompromised host. We report the first known case of Candida albicans tenosynovitis of the hand presenting as a mass in a boy with Buckley's immunodeficiency. Treatment was successful after radical synovectomy of both the flexor and extensor aspects of the hand after he failed to respond to combined amphotericin B and 5-fluorouracil therapy. Fungal tenosynovitis should be considered when swelling and decreased range of motion occur in the hands or digits of an immunocompromised host, especially if pain is not a prominent symptom.
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D002177:Candidiasis / Q000150:complications* / Q000188:drug therapy; D002648:Child; D005472:Fluorouracil / Q000627:therapeutic use; D006225:Hand / Q000382:microbiology / Q000601:surgery; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications; D008297:Male; D013710:Tendons / Q000601:surgery; D013717:Tenosynovitis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery
chemical_list: D000666:Amphotericin B; D005472:Fluorouracil