Acute increase of noradrenaline on vascular resistance in the corpus luteum of the pseudopregnant rat.
Noradrenaline infusion for 2 min (0.4 microgram/min) in anaesthetized rats increased the vascular resistance in 6-day-old corpora lutea, but had no significant effect on the vascular resistance in young (2-day-old) or old corpora lutea (11 days old). The luteal blood flow of the control rats was higher in 6-day-old corpora lutea than in those of 2 and 11 days. The luteal blood flow apparently lacks autoregulation, since a linear relationship between blood flow and arterial blood pressure was registered. The present study shows that, besides the well known metabolic effects of catecholamines on corpus luteum function, catecholamines can exert acute vascular effects, but only on the corpus luteum of pseudopregnancy in the middle of its life span.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D003338:Corpus Luteum / Q000098:blood supply* / Q000187:drug effects; D005260:Female; D009638:Norepinephrine / Q000494:pharmacology*; D011555:Pseudopregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012039:Regional Blood Flow; D014655:Vascular Resistance / Q000187:drug effects*
D009638:Norepinephrine