[Calcium-induced changes in bilayer membranes from oxidized cholesterol].
Elastic properties of oxidized cholesterol bilayers in n-octane and membrane solvent free were studied by measuring Young modulus E perpendicular in the direction perpendicular to the membrane plane as a function of concentration of calcium ions. Interaction between calcium ions and solvent free bilayers resulted in a significant increases of Young modulus E perpendicular in the concentration range 20-40 mmol/l Ca2+. It is suggested that the hardening of the membrane is caused by some structural changes in the hydrophobic region of the membrane.
D002118:Calcium / Q000494:pharmacology*; D002784:Cholesterol / Q000378:metabolism*; D008051:Lipid Bilayers; D008560:Membrane Fluidity; D010084:Oxidation-Reduction; D013718:Tensile Strength
D008051:Lipid Bilayers; D002784:Cholesterol; D002118:Calcium
Indutsirovannye kal'tsiem izmeneniia v bisloĭnykh membranakh iz okislennogo kholesterina.