title: Arterial intimal damage in avulsion and crush injuries in rat limbs.
abstract: A stereotypical pattern of arterial intimal damage has been demonstrated in rat avulsed and crushed injuries. These intimal tears can be found up to 6 cm proximal to the site of injury in avulsion injuries and are found at a delayed time with crush injuries. In both types of injury, circumferential intimal and subintimal tears spaced approximately 1 mm apart were demonstrated. These findings suggest a structural arrangement of the muscular artery wall that predisposes it to a reproducible pattern of damage. Veins undergoing the same avulsion and crushing procedure did not manifest any change. The presence of musculature rings or a weakened medial layer in artery walls after avulsion and crush injuries may influence short term patency and also long-term clinical replantation results.
mesh_terms: D000673:Amputation, Traumatic / Q000473:pathology*; D000818:Animals; D001158:Arteries / Q000293:injuries* / Q000473:pathology; D005263:Femoral Artery / Q000293:injuries; D006614:Hindlimb / Q000098:blood supply / Q000293:injuries*; D008855:Microscopy, Electron, Scanning; D051381:Rats; D014680:Veins / Q000473:pathology; D014949:Wounds, Nonpenetrating / Q000473:pathology*