[Malignant tumor of testicular gonadal stroma. Treatment by combined chemotherapy-radiotherapy].
The authors report the case of a 49-years-old man with an undifferentiated malignant gonadal stromal tumor of the right testis. Malignancy is confirmed by metastasis in the retroperitoneal lymph nodes. After 6 courses of chemotherapy with Cis-platinum, a retroperitoneal lymphadenectomy was performed and the section of the nodes showed a muscular differentiation of the tumor. This drug regimen did nod induce a complete response and an early recurrence occurs after lymphadenectomy which included the right ureter. The renal function was preserved by the way of a double J indwelling ureteral stent. A total remission was obtained with chemotherapy using Cis-platinum and 5-Fluorouracil, associated with a rapid fraction irradiation for six courses. Total response was assessed by scanner and by a laparotomy for bowel radiation sclerosis.
D003131:Combined Modality Therapy; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012086:Reoperation; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*
Tumeur maligne du stroma gonadique testiculaire. Traitement par une association chimiothérapie-radiothérapie.