Nitrous oxide ameliorates spasmodic torticollis.
In a case of therapy-resistant spasmodic torticollis administration of nitrous oxide (N2O) resulted in a dramatic transient amelioration of the dystonic movements. We suggest that manipulations of the opioid system may be useful in the therapy of this condition. Furthermore, our results with N2O may provide insight into the pathogenesis of the disease.
D004298:Dopamine / Q000502:physiology; D004723:Endorphins / Q000502:physiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009128:Muscle Spasticity / Q000188:drug therapy*; D009609:Nitrous Oxide / Q000627:therapeutic use*; D013268:Stimulation, Chemical; D014103:Torticollis / Q000188:drug therapy*
D004723:Endorphins; D009609:Nitrous Oxide; D004298:Dopamine