Prenatal stress and increased fluctuating asymmetry in the parietal bones of neonatal rats.
Recent studies have reported increased fluctuating dental and long bone asymmetry in neonates as a function of prenatal stress. The present study was designed to assess the effects of prenatal stress on a third calcium-dependent system, membranous bone. Pregnant rats were exposed to cold, heat, or noise from conception through parturition. Bilateral parietal bone lengths were measured in the term neonates. Levels of fluctuating asymmetry were found to be significantly increased (p less than .001) in all three stressed groups compared to unstressed controls. Results support the concept of a generalized stress response, and suggestions are offered for human osteological application.
D000818:Animals; D000831:Animals, Newborn; D003080:Cold Temperature; D005260:Female; D007839:Functional Laterality; D006358:Hot Temperature; D010294:Parietal Bone / Q000002:abnormalities / Q000196:embryology*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000503:physiopathology*