Inhibitory amino acid effects upon cortical evoked potentials.
The amplitude of both P1 and N1 waves of the cortical evoked potentials are significantly increased by topical application of GABA and taurine but not of glycine. This suggests a possible depressant effect of both GABA and taurine at superficial cortical layers.
D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects*; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D005998:Glycine / Q000494:pharmacology*; D051381:Rats; D013654:Taurine / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D013654:Taurine; D005680:gamma-Aminobutyric Acid; D005998:Glycine