[Effect of novocaine block of limbic system formations of the brain, hypothalamus and reticular formation on evoked potentials in the ventrobasal thalamic nucleus of the rat].
The effect of novocain on evoked potentials (EP) recorded from the ventrobasal complex (VBC) of rats thalamus has been studied during a single pulse stimulation of the contralateral hind paw immobilized with curare. It has been established that significant sinchronized decrease of amplitudes of all the three early components of EP has been observed during the novocain administration in the reticular thalamic nucleus, lateral amygdaloid area and septum. During the blocking of the anterior and posterior hypothalamus the amplitude of the second negative component of EP in VBC decreases, while during the blocking of the dorsal hypothalamus an increase of the amplitudes of all the three early components of EP is mainly observed.
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D007031:Hypothalamus / Q000187:drug effects*; D008032:Limbic System / Q000187:drug effects*; D008297:Male; D008839:Microelectrodes; D009407:Nerve Block; D011343:Procaine; D051381:Rats; D012154:Reticular Formation / Q000187:drug effects*; D013787:Thalamic Nuclei / Q000502:physiology*
D011343:Procaine
Vliianie blokirovaniia novokainom nekotorykh obrazovaniĭ limbicheskoĭ sistemy mozga, gipotalamusa i retikuliarnoĭ formatsii na vyzvannye potentsialy v ventrobazal'nom komplekse talamusa krysy.