Reduction of postoperative donor blood requirement by use of the cell separator.
In a prospective, randomized study of 20 patients undergoing elective open-heart surgery, up to c. one-third of the total intraoperative and postoperative transfusion requirement could be provided by autologous centrifuged blood. Retransfusion of washed, packed red blood cells freed from cellular debris, heparin and activated clotting factors significantly reduced blood loss during and after surgery. The cell separator is a valuable aid in autotransfusion technique.
D000328:Adult; D001779:Blood Coagulation Factors; D001804:Blood Transfusion, Autologous / Q000295:instrumentation*; D002315:Cardiopulmonary Bypass; D002469:Cell Separation / Q000295:instrumentation*; D005260:Female; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D011897:Random Allocation
D001779:Blood Coagulation Factors