Serum bactericidal activity against Legionella pneumophila.
Two strains of Legionella pneumophila serogroup 1 (UH1 and RH1) were incubated in fresh human serum. The UH1 strain was serum resistant, whereas the RH1 strain was serum susceptible. The bactericidal activity of fresh serum was abrogated by heating. Serum resistance of L. pneumophila strains may correlate with increased virulence.
D001770:Blood Bactericidal Activity; D006801:Humans; D007875:Legionella / Q000145:classification / Q000276:immunology*; D012703:Serotyping