title: Internodal microvillus-like Schwann cell fingers in myelinated fibres in mouse spinal roots.
abstract: Collections of microvillus-like Schwann cell fingers identical to those described previously in the nodal gap substance were commonly found along the internodes of large myelinated fibres in the spinal roots of adult mice. They were covered by Schwann cell basal lamina and focally protruded from the outer cytoplasmic Schwann cell compartment. Unlike nodal Schwann cell fingers, these internodal fingers had no contact with the axolemma, but were directed toward the endoneurium. These were not recognized in the distal peripheral nerves. The frequent occurrence of internodal Schwann cell fingers in the spinal root fibres suggests that these structures may be involved in some electrophysiological regulatory mechanism in this particular region of the nervous system.
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure; D051379:Mice; D008810:Mice, Inbred C57BL; D008813:Mice, Inbred ICR; D008854:Microscopy, Electron; D008871:Microvilli / Q000648:ultrastructure; D009413:Nerve Fibers, Myelinated / Q000648:ultrastructure*; D011901:Ranvier's Nodes / Q000648:ultrastructure*; D012583:Schwann Cells / Q000648:ultrastructure*; D013126:Spinal Nerve Roots / Q000648:ultrastructure*