[Levels of labile phosphorus-containing metabolites].
The work deals with the investigation of possible use of 31P-NMR for revealing metabolism changes in the mouse liver during the development of leukemia. This method was shown to permit observation of the extreme pattern of relative concentrations of sugar phosphate and bioorganic phosphate in the latent period. This observed increase in the metabolic activity of hepatocytes correlates with biophysical shifts found by other methods.
D000818:Animals; D007942:Leukemia, Experimental / Q000188:drug therapy / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008970:Molecular Weight; D010710:Phosphates / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism*; D013997:Time Factors; D014750:Vincristine / Q000627:therapeutic use
D010710:Phosphates; D010758:Phosphorus; D014750:Vincristine
Soderzhanie labil'nykh fosforsoderzhashchikh metabolitov.