[Specific growth rate and macrophagal infiltration of experimental tumors].
The relationship between the macrophage infiltration and the specific growth rate of tumours was studied by the technique of spontaneous migration of lymphoreticular cells from tissue fragments. In the case of dimethylnitrosamine-induced rat kidney tumours and Ehrlich solid tumour in mice the increased migration of activated macrophages was associated with the average specific growth rate. The macrophage infiltration of tumours and systemic immune reactivity to tumour-associated antigens depend probably on tumour cell kinetics.
D000818:Animals; D000831:Animals, Newborn; D002286:Carcinoma, Ehrlich Tumor / Q000276:immunology; D002465:Cell Movement; D004128:Dimethylnitrosamine; D005260:Female; D007680:Kidney Neoplasms / Q000139:chemically induced / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology; D008262:Macrophage Activation; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D012157:Mononuclear Phagocyte System / Q000276:immunology; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000276:immunology*; D051381:Rats; D012513:Sarcoma, Experimental / Q000139:chemically induced / Q000276:immunology
D004128:Dimethylnitrosamine
Udel'naia skorost' rosta i makrofagal'naia infil'tratsiia éksperimental'nykh opukholeĭ.