title: Thirty-five-day modified red cells and 7-day stored platelet concentrates from triple bags of identical PVC formulation.
abstract: There is continuous need for blood components with long shelf life. To this end the 'circle' triple pack has been modified to provide 35-day red cell and 7-day platelet concentrates, in PVC bags of identical formulation and 0.4 mm thick. The plasticizer is a mixture of DEHP and TOTM (CLX Mark II). The primary pack contains 63 ml of CP 277.5 mM glucose. The third pack contains 100 ml of citric acid 2 mM, trisodium citrate 20 mM, NaH2PO4 20 mM, NaCl 123 mM, glucose 40 mM, and adenine 1.26 mM. Plasma is adenine-free. With these modifications both hard- and soft-spun red cells gave satisfactory biochemical and autologous survival indices up to 35 days of storage, the haematocrit not exceeding 60%. Platelet concentrates were acceptable at 7 days of shelf-life.
mesh_terms: D000255:Adenosine Triphosphate / Q000032:analysis; D001792:Blood Platelets / Q000648:ultrastructure; D001793:Blood Preservation / Q000295:instrumentation*; D002021:Buffers; D004905:Erythrocyte Aging; D005947:Glucose / Q000032:analysis; D006461:Hemolysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008854:Microscopy, Electron; D010968:Plasticizers; D011143:Polyvinyl Chloride; D011145:Polyvinyls; D013997:Time Factors
chemical_list: D002021:Buffers; D010968:Plasticizers; D011145:Polyvinyls; D000255:Adenosine Triphosphate; D011143:Polyvinyl Chloride; D005947:Glucose