Topographic studies with 32P tumor marker during operations of brain tumors.
A method for the intraoperative detection of brain tumor propagation is described. Based on the well-known radiophosphorus test, a very sensitive semiconductor probe was tested in 16 brain tumor operations. With this miniaturized sensor, the beta-emission of 32P could be measured with a high topographical resolution. Especially in high-grade gliomas, in meningiomas and in metastases a good discrimination of normal and tumor-infiltrated tissue was possible. The perspectives of a technical improvement of this method and the application of more specific tumor markers are discussed.
D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery; D008579:Meningioma / Q000000981:diagnostic imaging / Q000601:surgery; D008875:Middle Aged; D010761:Phosphorus Radioisotopes; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed
D010761:Phosphorus Radioisotopes