Flow determination using computed tomography: application to aortic dissection. Part II.
Dynamic CT is not only useful in imaging an aortic dissection but may provide additional information concerning the hemodynamic significance of differing flow patterns in the false channel compared with the true channel. Once validated, the computed tomographic (CT) method of flow determination (See Part I) was applied to an experimental animal model with a surgically created aortic dissection. Good correlation was obtained for the flow estimates of cardiac output derived for the true and false channel (r = .82). The shapes of the curves, however, were distinct, reflecting different flow patterns for the true and false channels. Curve parameters, such as peak CT number (P = .0001), variance (P = .006), and, in particular, the number of mixers (a parameter used to quantify the degree of mixing) (P = .0001), demonstrated significant differences between the two channels of the dissection. The curve parameters derived can therefore be used to differentiate the true and false channels and may then predict the long-term outcome of the false channel, and the aortic branches derived from it.
D000784:Aortic Dissection / Q000000981:diagnostic imaging* / Q000503:physiopathology; D000818:Animals; D001014:Aortic Aneurysm / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002302:Cardiac Output; D003326:Coronary Circulation; D004285:Dogs; D014057:Tomography, X-Ray Computed