Effect of nerve stimulation on rat skeletal muscle. A study of plasma membrane.
The gastrocnemius muscle of the rat showed no morphological, histometric or plasma membrane changes, after sciatic nerve stimulation with a 5mA current for 30 to 60 min, 10 mA for 30 min and 15 mA for 5 min. However, 10 mA for 60 and 200 min gave rise to mitochondrial and plasma membrane abnormalities. These changes were absent after a rest period. The results indicated that the sciatic nerve stimulation at 10 mA for 60 and 200 min caused reversible changes in the rat skeletal muscle mitochondria and plasma membrane.
D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure*; D004558:Electric Stimulation; D006651:Histocytochemistry; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure; D009132:Muscles / Q000294:innervation* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve / Q000502:physiology*