[Comparative evaluation of the therapeutic effectiveness of virazole and remantadine in patients with influenza caused by A(H3N2) and B viruses].
Therapeutic effectiveness of virazole in treatment of patients with influenza caused by A (H3N2) and B viruses (1980-1984) was demonstrated in 432 patients with the laboratory-confirmed diagnosis of influenza. Provided the treatment started on the 1st day of the disease, the experimental group showed normalization of fever and regression of toxicity symptoms within shorter periods than the controls. However in treatment of patients with influenza caused by A (H3N2) virus virazole showed a less marked therapeutic effect than the Soviet antiinfluenza drug, remantadine.
D000218:Adamantane / Q000031:analogs & derivatives*; D004341:Drug Evaluation; D006801:Humans; D053122:Influenza A Virus, H3N2 Subtype; D009980:Influenza A virus; D009981:Influenza B virus; D007251:Influenza, Human / Q000188:drug therapy*; D012254:Ribavirin / Q000627:therapeutic use*; D012263:Ribonucleosides / Q000627:therapeutic use*; D012299:Rimantadine / Q000627:therapeutic use*; D013997:Time Factors
D012263:Ribonucleosides; D012299:Rimantadine; D012254:Ribavirin; D000218:Adamantane
Sravnitel'naia otsenka terapevticheskoĭ éffektivnosti virazola i remantadina u bol'nykh grippom, vyzvannym virusami A(H3N2) i B.