Activities of L-lactate and glycerol phosphate production rates in vitro from glucose 6-phosphate in regenerating rat liver.
Activities of L-lactate and glycerol phosphate production in vitro were assayed in regenerating rat liver at different times after partial hepatectomy and were compared with activities of sham operated controls. Results show an oscillatory shift in these activities with smallest values for both L-lactate and glycerol phosphate production rates at 20 hr, these being 80% and 50%, respectively of normal values, and with highest values at 42 hr where these rates were 150% and 125%, respectively, both recovering their original state 60 hr after surgery. From these data it is concluded that in regenerating liver there are changes in the ability of the glycolysis system to produce L-lactate and glycerol phosphate.
D000818:Animals; D005260:Female; D019298:Glucose-6-Phosphate; D005958:Glucosephosphates / Q000378:metabolism*; D005994:Glycerophosphates / Q000096:biosynthesis*; D006019:Glycolysis; D007700:Kinetics; D007773:Lactates / Q000096:biosynthesis*; D008099:Liver / Q000378:metabolism*; D008115:Liver Regeneration; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D005958:Glucosephosphates; D005994:Glycerophosphates; D007773:Lactates; D019298:Glucose-6-Phosphate