title: Fall in the heat-labile alkaline phosphatase isoenzyme levels during pregnancy in healthy Nigerians.
abstract: Estimation of heat-labile alkaline phosphatase isoenzyme in the serum of 45 healthy non-pregnant women and 98 women in the second and third trimesters of pregnancy revealed a statistically significant reduction of this isoenzyme during pregnancy. Variations in normal activity were also more marked in the pregnant women compared with the non-pregnant control subjects. Now that normal serum levels of the heat-labile alkaline phosphatase isoenzyme in pregnancy have been established it is possible to use estimations of the enzyme as part of the assessment of maternal liver function in pregnancy.
mesh_terms: D000293:Adolescent; D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood*; D005260:Female; D006358:Hot Temperature; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D009549:Nigeria; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third
chemical_list: D007527:Isoenzymes; D000469:Alkaline Phosphatase