[Contribution of anatomic verification of the fetus and newborn infant in diagnosis and genetic counseling. Apropos of 221 autopsies].
The authors report the results of 221 post-mortem examinations of fetuses, newborns, and infants performed during 26 months and theirs involvements in genetic counselling. 10,8% of these cases are provided by therapeutic terminations of pregnancy; necropsy confirmed the diagnosis afforded except for maternal infectious diseases contracted during pregnancy in which post-mortem examination revealed generally no abnormality. Genetic diseases represented 33,7%: in these cases anatomic examination took variable role, it is more important in multivisceral malformative syndromes, sudden death of infancy, and histologically prominent feature diseases. In 38,5% of cases, medical acquired disease were found; it elucidated cause of death and generally permitted to carry out favourable genetic counselling. At least 17,1% of cases stayed unexplained after necropsy.
D001344:Autopsy; D005260:Female; D005313:Fetal Death / Q000235:genetics / Q000473:pathology*; D005315:Fetal Diseases / Q000175:diagnosis; D005817:Genetic Counseling; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000235:genetics / Q000401:mortality / Q000473:pathology*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012189:Retrospective Studies
Apport de la vérification anatomique du foetus et du nouveau-né pour le diagnostic et le conseil génétique. A propos de 221 autopsies.