title: Human leukocyte interferon does not inhibit alfalfa mosaic virus in protoplasts or tobacco tissue.
abstract: Enzyme-linked immunosorbent assays and local lesion infectivity assays showed that recombinant leukocyte interferons, rIFN-alpha A and rIFN-alpha D, did not reproducibly affect the accumulation of alfalfa mosaic virus in tobacco leaf discs or in tobacco or alfalfa protoplasts when applied within 1 hr after inoculation with virus.
mesh_terms: D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology*; D007700:Kinetics; D000455:Medicago sativa; D009029:Mosaic Viruses / Q000187:drug effects / Q000254:growth & development*; D010947:Plants, Toxic; D011523:Protoplasts / Q000502:physiology; D014026:Nicotiana
chemical_list: D007370:Interferon Type I