Uveitis with allergy to candidin.
By skin testing, 21 patients with uveitis were more reactive to Candida extracts than a control group of patients during the same 15-year follow-up period. Skin testing with candidin induced an obvious and transient change of the course of the ocular disease in 19 patients and led to systemic symptoms in 15 patients; 11 were atopic, 17 had intermediate uveitis. Antifungal treatment and/or desensitization improved the ocular condition in 16 patients. The real pathogeny of these uveitides remains hypothetical.
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents / Q000276:immunology* / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000276:immunology*; D005260:Female; D006801:Humans; D018942:Macrolides; D008297:Male; D008875:Middle Aged; D011090:Polyenes / Q000276:immunology; D012882:Skin Tests; D014605:Uveitis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D018942:Macrolides; D011090:Polyenes; C010428:candidin