title: The effect of intragastric infusion of glucose, lipids or acetate on fasting nitrogen excretion and blood metabolites in sheep.
abstract: Two experiments are reported in which the effect of the intragastric infusion of non-protein energy on fasting nitrogen losses was studied. Expt 1 was a preliminary trial with two 35 kg lambs given 0, 144, 288 or 432 kJ/kg live weight (W)0.75 per d as lipid or glucose infused into the abomasum for periods of 3 d. Expt 2 was of a 4 X 4 Latin square design with four sheep of about 30 kg live weight. The four treatments were control (fasted with water infusion), or the infusion of 144 kJ/kg W0.75 per d as glucose or lipid into the abomasum or as acetic acid into the reticulo-rumen. Compared with the fasted control, glucose infusion reduced (P less than 0.05) N excretion to about 0.6 of that of the control, increased (P less than 0.05) plasma glucose, decreased (P less than 0.05) plasma urea and beta-hydroxybutyrate, and was without effect on plasma amino-N or creatinine excretion. Lipid and acetate infusions were without statistically significant effect on N or creatinine excretion or any of the blood indices measured, with the exception of plasma glucose which was reduced (P less than 0.05) with acetate infusion.
mesh_terms: D000018:Abomasum; D000085:Acetates / Q000494:pharmacology*; D000818:Animals; D001774:Blood Chemical Analysis; D005215:Fasting; D005947:Glucose / Q000494:pharmacology*; D007441:Intubation, Gastrointestinal; D008055:Lipids / Q000494:pharmacology*; D008297:Male; D009584:Nitrogen / Q000652:urine*; D012417:Rumen; D012756:Sheep / Q000097:blood / Q000378:metabolism*
chemical_list: D000085:Acetates; D008055:Lipids; D005947:Glucose; D009584:Nitrogen