Cardiac pacing and central hemodynamics in experimental propoxyphene induced shock.
Coronary sinus pacing was evaluated in 10 pigs with propoxyphene induced cardiac failure. During the early phase of intoxication cardiac pacing improved cardiac function slightly but significantly worsened it in severely intoxicated animals. The results are consistent with marked negative inotropic action of propoxyphene in overdose.
D000818:Animals; D002304:Cardiac Pacing, Artificial; D011431:Dextropropoxyphene / Q000506:poisoning*; D006439:Hemodynamics / Q000187:drug effects*; D012769:Shock / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D013552:Swine
D011431:Dextropropoxyphene