[Relative biological effectiveness of tritium oxide based on nucleic acid metabolic indices].
Relative biological effectiveness (RBE) of tritium oxide, as compared to gamma-rays (137Cs), with regard to LD50/30 is 2,32 +/- 0,69 for rats. The RBE coefficients for tritium oxide are obtained with regard to some indices of nucleic acid metabolism in the thymus and spleen during the dose formation (0-14 days). The RBE of tritium oxide increases with a decrease in radiation dose as determined according to the concentration and content of DNA per organ and activity of thymus DNAases.
D000818:Animals; D002588:Cesium Radioisotopes; D004247:DNA / Q000378:metabolism*; D003851:Deoxyribonucleases / Q000378:metabolism; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D008297:Male; D011833:Radiation Injuries, Experimental / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012062:Relative Biological Effectiveness; D013154:Spleen / Q000378:metabolism; D013950:Thymus Gland / Q000378:metabolism; D014316:Tritium; D014867:Water
D002588:Cesium Radioisotopes; D014867:Water; D014316:Tritium; C033961:tritium oxide; D004247:DNA; D003851:Deoxyribonucleases
Otnositel'naia biologicheskaia éffektivnost' okisi tritiia po pokazateliam metabolizma nukleinovykh kislot.