An improved procedure of chronic intravenous infusion in unrestrained rats.
A continuous infusion technique for rats is described which is a significant improvement upon existing procedures with regard to the degree of physiological and psychological stress it provokes. The system was assembled with a head attachment, a practical swivel and a special metabolic cage, permitting long-term tube feeding of unrestrained rats.
D000818:Animals; D007263:Infusions, Parenteral / Q000295:instrumentation / Q000379:methods*; D008297:Male; D010600:Pharmacology / Q000295:instrumentation / Q000379:methods*; D051381:Rats