Mapping of cholinoceptive(nicotinoceptive)neurons in the lower brainstem: with special reference to the ventral surface of the medulla.
The distribution of cholinoceptive neurons in the lower brainstem of the rat was investigated by means of a histochemical method for specific acetylcholinesterase. Nicotinoceptive neurons were characterized using an alpha-bungarotoxin-horseradish peroxidase conjugate for the detection of nicotinic acetylcholine receptors. For the first time a nearly complete mapping of the location of cholinoceptive (nicotinoceptive) neurons of the lower brainstem was achieved. Special attention was focused on the organization of the cholinoceptive neuronal matrix of the ventral surface of the medulla, where regulative centers for vasomotor and respiratory control are located.
D000110:Acetylcholinesterase / Q000032:analysis*; D000818:Animals; D001931:Brain Mapping; D001933:Brain Stem / Q000166:cytology* / Q000201:enzymology / Q000502:physiology; D002038:Bungarotoxins / Q000032:analysis; D005260:Female; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology / Q000201:enzymology / Q000502:physiology; D009474:Neurons / Q000032:analysis* / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains; D011950:Receptors, Cholinergic / Q000502:physiology*; D011978:Receptors, Nicotinic / Q000502:physiology
D002038:Bungarotoxins; D011950:Receptors, Cholinergic; D011978:Receptors, Nicotinic; D006735:Horseradish Peroxidase; D000110:Acetylcholinesterase