Natural killer activity in two cases of ataxia telangiectasia.
We report two cases of ataxia telangiectasia in which a small number of T cells and a slightly diminished response to phytohaemagglutinin or concanavalin A were observed. In one case, serum IgA was undetectable. In spite of T and/or B cell involvement, natural killer activity and the percentage of natural killer cells determined by monoclonal antibodies Leu 7 were normal in both cases.
D000293:Adolescent; D000911:Antibodies, Monoclonal / Q000032:analysis; D001260:Ataxia Telangiectasia / Q000276:immunology*; D002455:Cell Division; D002648:Child; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007694:Killer Cells, Natural / Q000032:analysis*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology; D008297:Male
D000911:Antibodies, Monoclonal; D007136:Immunoglobulins