title: The compression of granulates containing solid dispersions.
abstract: In the present work granulates containing solid dispersions of diazepam were compressed into tablets. The results show that polyethyleneglycol (PEG 6000) give the best tablets which disintegrate when a strong disintegrant is added extragranularly. The tablets keep their good physical properties when stored in normal or low humidity conditions.
mesh_terms: D002626:Chemistry, Pharmaceutical; D004339:Drug Compounding; D004355:Drug Stability; D006813:Humidity; D011092:Polyethylene Glycols; D011208:Powders; D011312:Pressure; D012995:Solubility; D013607:Tablets
chemical_list: D011208:Powders; D013607:Tablets; D011092:Polyethylene Glycols