Influence of arterial occlusion on hematocrit and plasma protein concentration of femoral venous blood in rabbit.
The changes of venous outflow (Qv), hematocrit (Hct), total plasma protein (Tp), electrolytes, crystalloid osmolality, PO2, PCO2, and pH were simultaneously measured in hindlimb preparation of anesthetized rabbits during 5 min occlusion of the femoral artery and the abdominal aorta and during the reactive hyperemia. During the occlusion of the femoral artery, Qv decreased to 66.4% at the end of the occlusion. Hct and Tp decreased slightly and then tended to progressively increase. PO2 showed an increasing trend following an initial decrease. During the occlusion of the aorta, Qv showed a continuous drop to 38.0%, while Hct and Tp declined to 95.4 and 93.8%, respectively. Qv, Hct, and Tp showed increase after the release of the occlusion of the femoral artery and the aorta. Crystalloid osmolality and K+ were observed to rise slightly. From these results it was suggested (1) that the increase of Hct and Tp which represents the hemoconcentration occurred during the reactive hyperemia and during the occlusion of the femoral artery, while the hemodilution occurred during the aortic occlusion, and (2) that the gradual increase of Hct and Tp during the occlusion of the femoral artery would be caused by the collateral blood flow.
D000818:Animals; D001769:Blood; D001798:Blood Proteins / Q000378:metabolism*; D002712:Chlorides / Q000097:blood; D005260:Female; D005263:Femoral Artery / Q000502:physiology*; D005268:Femoral Vein / Q000502:physiology*; D006400:Hematocrit; D006863:Hydrogen-Ion Concentration; D008297:Male; D009994:Osmolar Concentration; D011188:Potassium / Q000097:blood; D011817:Rabbits; D012039:Regional Blood Flow; D012964:Sodium / Q000097:blood
D001798:Blood Proteins; D002712:Chlorides; D012964:Sodium; D011188:Potassium