High-dose intravenous immunoglobulin for post-transfusion purpura.
Five patients with post-transfusion purpura (four due to Zw(a), one presumably due to HLA antibodies) were treated with intravenous immunoglobulin (IgG) at doses of 0.4 g per kg body weight. IgG therapy was immediately effective as indicated by cessation of bleeding and rise of platelet counts in four out of five cases.
D000328:Adult; D000368:Aged; D001327:Autoimmune Diseases / Q000209:etiology / Q000628:therapy*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage*; D007275:Injections, Intravenous; D008875:Middle Aged; D010976:Platelet Count; D011696:Purpura, Thrombocytopenic / Q000209:etiology / Q000628:therapy*; D065227:Transfusion Reaction
D007074:Immunoglobulin G