title: Radionuclide studies in upper gastro-intestinal ulceration--are they reliable? A pilot study of 6 patients.
abstract: Endoscopy is at present the diagnostic technique of choice in the evaluation and detection of upper gastro-intestinal tract ulceration. Because of the physical discomfort suffered by patients during endoscopic examination, the search for better and less invasive methods of examination (especially in the unco-operative and seriously ill patient) continues. According to reports from the Orient, sucralfate (Ulsanic; Continental Ethicals) has prominent ulceravid properties. These properties are being used in conjunction with a tagging agent, in this case technetium-99m, as a diagnostic method for the detection and localization of upper gastro-intestinal ulceration. In this pilot study on 6 patients the positive findings of others regarding the specificity and promise of this method could not be confirmed.
mesh_terms: D000368:Aged; D000535:Aluminum; D004381:Duodenal Ulcer / Q000000981:diagnostic imaging*; D006801:Humans; D015609:Organotechnetium Compounds; D010437:Peptic Ulcer / Q000000981:diagnostic imaging*; D010865:Pilot Projects; D011877:Radionuclide Imaging; D013276:Stomach Ulcer / Q000000981:diagnostic imaging*; D013392:Sucralfate; D013667:Technetium
chemical_list: D015609:Organotechnetium Compounds; C038248:technetium Tc 99m sucralfate; D013392:Sucralfate; D013667:Technetium; D000535:Aluminum