title: Wall motion in expiratory flow limitation: choke and flutter.
abstract: Limitation of expiratory airflow from mammalian airways is currently understood to be due to choking at wave speed (S. V. Dawson and E. A. Elliott. J. Appl. Physiol. 43: 498-515, 1977). A critical weakness of the theory is the lack of a mechanism for the dissipation of energy when effort exceeds that needed for maximal flow. We have observed substantial wall motion with flow limitation in a physical model of a trachea. Therefore we have examined a simple two-dimensional mathematical model, designed to approximate the behavior of the physical model of the trachea, to try to identify a relationship between flow limitation and wall oscillation. The model matches wave-speed predictions when only long waves are considered. The model predicts that aerodynamic flutter will occur in the zone of supercritical flow described in wave-speed theory. Aerodynamic flutter in the zone of supercritical flow provides a potential mechanism for the energy dissipation necessary for transition from supercritical to subcritical flow and explains the high-frequency pure tone heard with flow limitation.
mesh_terms: D000402:Airway Obstruction / Q000503:physiopathology; D000818:Animals; D008954:Models, Biological; D008961:Models, Structural; D012123:Pulmonary Ventilation; D014132:Trachea / Q000502:physiology*