REM sleep latency and contingent negative variation in endogenous depression. Suggestion for a common cholinergic mechanism.
In a sample of 13 endogenous depressive inpatients, REM (rapid eye movement) latency (recorded over 4 consecutive nights after 2 habituation nights) and contingent negative variation amplitude showed significant relationship, suggesting that both parameters may depend on the same mechanisms, possibly cholinergic.
D000328:Adult; D001921:Brain / Q000503:physiopathology*; D002799:Cholinergic Fibers / Q000502:physiology; D003265:Contingent Negative Variation; D003866:Depressive Disorder / Q000503:physiopathology*; D004594:Electrophysiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology; D012895:Sleep, REM / Q000502:physiology*