title: A case of bone fluorosis of undetermined origin.
abstract: After predominant theories on the causes of fluorosis are described and remarks made about the metabolism of fluoride, an observation of bone fluorosis in a 64-year-old patient is reported. Because, despite painstaking research, none of the known causes of bone fluorosis could be found in our patient, a new pathomechanism is being offered for discussion, i.e., increased renal or intestinal absorption or an increase of fluoride deposited in the bone; i.e., an inborn or acquired error of fluoride metabolism. We recently observed a similar case with none of the well-known origins.
mesh_terms: D001851:Bone Diseases, Metabolic / Q000175:diagnosis / Q000209:etiology*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005459:Fluorides / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D011859:Radiography
chemical_list: D005459:Fluorides