[Combined low-dose radiation and adriblastin therapy of lung metastases].
Two patients with lung metastases are presented who were submitted to a combined low-dose radiotherapy and adriamycin monotherapy with good palliative results. The mode of action as well as the experimental examination results are discussed. The ineffectiveness of single low-dose chemotherapy is demonstrated by the non-response of lung metastases beyond the irradiation fields (heart block, diaphragm). Both patients were resistant to chemotherapy.
D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D002277:Carcinoma / Q000473:pathology; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D011033:Podophyllin / Q000031:analogs & derivatives / Q000627:therapeutic use; D011034:Podophyllotoxin / Q000031:analogs & derivatives; D011867:Radioisotope Teletherapy; D014594:Uterine Neoplasms / Q000473:pathology
D003037:Cobalt Radioisotopes; C003170:mitopodozide; D004317:Doxorubicin; D003520:Cyclophosphamide; D011033:Podophyllin; D011034:Podophyllotoxin; D008727:Methotrexate
Kombinierte niedrig dosierte Strahlen- und Adriblastintherapie von Lungenmetastasen.