title: [Systemic mastocytosis without skin involvement. Presentation of a case and review of the literature].
abstract: A case of SMCD without apparent cutaneous involvement is described. It has however been possible to demonstrate, by a test of cutaneous biopsy at the optical and electron microscope, an increased number of aberrant mast cells, together with a cutaneous melanosis due to the intense melanin deposit. The meaning of this association is unknown and never previously notified in the literature.
mesh_terms: D000368:Aged; D001706:Biopsy; D001707:Biopsy, Needle; D003594:Cytoplasmic Granules; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008407:Mast Cells / Q000648:ultrastructure; D008543:Melanins; D012867:Skin / Q000473:pathology; D014582:Urticaria Pigmentosa / Q000473:pathology*
chemical_list: D008543:Melanins
vernacular_title: Mastocitosi sistemica senza interessamento cutaneo. Presentazione di un caso e revisione della letteratura.