[Effect of enkephalins on metabolic indices in experimental myocardial infarct in rats].
An experimental study in rats demonstrated that myocardial infarction, induced by the ligation of the descending branch of the left coronary artery, led to marked metabolic disorders, such as increased lactate and glucose levels and decreased levels of blood calcium and magnesium and hepatic glycogen. A stable analogue of leu-enkephalin administered to the animals normalized metabolic parameters and improved the course of experimental myocardial infarction in rats.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002118:Calcium / Q000097:blood; D004231:Diuresis / Q000187:drug effects; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D007773:Lactates / Q000097:blood; D008112:Liver Glycogen / Q000378:metabolism; D008274:Magnesium / Q000097:blood; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000378:metabolism; D051381:Rats
D001786:Blood Glucose; D007773:Lactates; D008112:Liver Glycogen; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; D008274:Magnesium; D002118:Calcium; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Vliianie énkefalinov na metabolicheskie pokazateli pri éksperimental'nom infarkte miokarda u krys.