title: [The toxicologic evaluation of biomaterials. 1. Results of biomaterial tests in cultures of human amnion epithelial cells and human fibroblasts].
abstract: Cell cultures are a highly sensitive toxicological model used also for the testing of biomaterials. Beside the safety tests provided in the Pharmacopoeia of GDR cultures from human amnionepithelial cells and fibroblasts are used. The paper reports the results of some methodical investigations concerning the procedure of extraction of biomaterials, the evaluation of test results and the comparison with the results of other biological tests.
mesh_terms: D000650:Amnion / Q000166:cytology / Q000187:drug effects; D001672:Biocompatible Materials / Q000009:adverse effects*; D002478:Cells, Cultured; D004847:Epithelial Cells; D004848:Epithelium / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D011143:Polyvinyl Chloride
chemical_list: D001672:Biocompatible Materials; D011143:Polyvinyl Chloride
vernacular_title: Beiträge zur toxikologischen Bewertung von Biomaterialien. 1. Mitteilung: Ergebnisse von Biomaterial-Prüfungen an Kulturen von Human-Amnionepithelzellen und Human-Fibroblasten.