Unusual response following use of succinylcholine in a horse anesthetized with halothane.
A syndrome similar to malignant hyperthermia developed in a 545-kg Quarter Horse while anesthetized with halothane for cataract removal. Succinylcholine administration caused prolonged, severe muscle fasciculations followed by tachycardia, and an elevated blood pressure. Later, while the horse was still under anesthesia, its body temperature rose 2 degrees C, and respiratory acidosis developed. Myositis developed after surgery, but the horse recovered.
D000768:Anesthesia, General / Q000662:veterinary*; D000818:Animals; D005260:Female; D006221:Halothane; D006734:Horse Diseases / Q000139:chemically induced*; D006736:Horses; D008305:Malignant Hyperthermia / Q000662:veterinary*; D009119:Muscle Contraction / Q000187:drug effects; D013390:Succinylcholine / Q000009:adverse effects*; D013610:Tachycardia / Q000139:chemically induced / Q000662:veterinary*
D013390:Succinylcholine; D006221:Halothane