[Action of benzohydrothiochromylium salts on bacterial membranes].
Cultivation of Staphylococcus 209-P and Micrococcus lysodeikticus cells on media containing new antibacterial preparations--iodide and trifluoroacetate derivatives of benzohydrothiochromylium resulted in a remarkable lesion of the membrane respiratory apparatus, i.e. the amounts of membrane polypeptides, the specific concentration of cytochromes, the activities of reductases and oxidases--NADH, malate and lactate decreased. Profound changes in the cell cytology were observed.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D001426:Bacterial Proteins / Q000378:metabolism; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D008563:Membrane Lipids / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D008837:Micrococcus / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure; D008854:Microscopy, Electron; D010100:Oxygen / Q000378:metabolism; D011714:Pyrans / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000378:metabolism / Q000648:ultrastructure
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D008563:Membrane Lipids; D008565:Membrane Proteins; D011714:Pyrans; D010100:Oxygen
Deĭstvie soleĭ benzogidrotiokhromiliia na membrannyĭ apparat bakteriĭ.