Changes in the colonic temperature and metabolism during immobilization stress in repetitively immobilized or cold-acclimated rats.
Effect of immobilization stress on the rat colonic temperature and metabolism was studied in a warm environment of 25 degrees C. Immobilization for 3 hr caused hyperthermia accompanied by increased oxygen consumption (VO2) in the warm controls. The hyperthermic effect of immobilization was accelerated after 1 week repetition of daily immobilization and it was lessened after 2 to 4 week repetition of daily immobilization. The magnitude of VO2 increase was the same throughout the experimental period of 4 weeks during the immobilization. Hypothermia was never observed during immobilization. Immobilization-induced hyperthermia was significantly potentiated in the cold-acclimated rats, while VO2 increase did not differ between cold-acclimated rats and warm controls. These results suggest that immobilization stress causes the changes in body temperature through thermogenic and heat-loss mechanisms.
D000704:Analysis of Variance; D000818:Animals; D001481:Basal Metabolism; D001833:Body Temperature Regulation; D001835:Body Weight; D003080:Cold Temperature; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013312:Stress, Physiological / Q000503:physiopathology*; D013997:Time Factors