Ultrastructural study of long spacing collagen fibres and basal lamina in malignant schwannoma.
It was found by electron microscopy that extracellular darkly stained materials (DSM) observed abundantly in a case of malignant schwannoma were closely related to both basal lamina and fibrous long spacing collagen (FLS). The FLS were characterized by the cross bands with a 95 nm periodicity, and longitudinally aligned filaments, 9 nm in diameter, while DSM consisted of amorphous material, and 9 nm filaments. The filaments in DSM and FLS were similar in diameter and morphology to reticular fibres in basal laminae. The DSM were continuous with both dark bands of FLS and basal laminae. These results indicate that basal laminae may be the common origin of DSM and FLS. Ultrastructural features of longitudinal, transverse and oblique sections were described.
D000368:Aged; D003094:Collagen; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009442:Neurilemmoma / Q000648:ultrastructure*
D003094:Collagen