title: Glutathione peroxidase activity and reduced glutathione content in erythrocytes of patients with chronic renal failure.
abstract: Erythrocytes from 18 patients with chronic renal failure (CRF) and 10 healthy subjects were examined with respect to glutathione peroxidase (GSH-Px) activity and reduced glutathione (GSH) contents. The activity of GSH-Px and GSH content were found to be lower in RBC from CRF patients as compared with normal RBC. These reduced levels of GSH and GSH-Px in the red cells of uraemic patients may predispose the cells to oxidative damage.
mesh_terms: D000328:Adult; D004912:Erythrocytes / Q000032:analysis* / Q000201:enzymology; D005978:Glutathione / Q000097:blood*; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D008875:Middle Aged
chemical_list: D005979:Glutathione Peroxidase; D005978:Glutathione