Effects of adjuvants to local anaesthetics on their duration. IV. Effect of hyaluronic acid added to bupivacaine or prilocaine on the duration of nerve blockade in man.
A randomized study of the duration of ulnar nerve blockade induced with 2% prilocaine or 0.5% bupivacaine with and without 0.4% hyaluronic acid was performed in volunteers. In contrast to results in experimental animals, the addition of hyaluronic acid to the local anaesthetic solution did not affect the duration of sensory nerve block.
D000759:Adjuvants, Anesthesia / Q000494:pharmacology*; D000328:Adult; D002045:Bupivacaine / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D011318:Prilocaine / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D000759:Adjuvants, Anesthesia; D011318:Prilocaine; D006820:Hyaluronic Acid; D002045:Bupivacaine