title: [Morphologic and functional changes in the pancreas following acute necrotizing pancreatitis].
abstract: Acute necrotizing pancreatitis according to the presented results leads to definite endo- and/or exocrine functional loss in 57% of the patients (n = 21, pancreatic necrosis ascertained by laparotomy) evaluated by orale glucose tolerance test, secretin-ceruletide-test and fluorescein-dilaurate-test. Morphological alterations developed in 76% of patients, predominantly cicatricial ductal lesions shown by ERCP. The finding of a normal pancreatic function after extended necrosis in 43% of the patients can be explained by the enormous functional reserve of the pancreatic gland.
mesh_terms: D000208:Acute Disease; D002760:Cholangiopancreatography, Endoscopic Retrograde; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010179:Pancreas / Q000473:pathology; D010186:Pancreatic Function Tests; D010195:Pancreatitis / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
vernacular_title: Morphologische und funktionelle Veränderungen des Pankreas nach akuter nekrotisierender Pankreatitis.