A new design for a liquid scintillation counter for micro samples using a flat-bed geometry.
A new design for a liquid scintillation counter based on a flat-bed geometry is described. Micro-samples are dried or filtered onto transfer membranes or glass fibre filters in a 6 X 16 matrix, compatible with 96-well micro-titration plate filtration assays of labelled cells. A prototype counter without lead shielding had low background countrates (2-3 cpm for 3H) giving a figure of merit of 1325 (and 1292 for 14C). Only 5-15 ml of scintillant/96 samples are required and thus the volume of radioactive waste is low.
D004247:DNA / Q000032:analysis*; D009693:Nucleic Acid Hybridization; D010761:Phosphorus Radioisotopes; D012588:Scintillation Counting / Q000295:instrumentation* / Q000379:methods; D013462:Sulfur Radioisotopes
D010761:Phosphorus Radioisotopes; D013462:Sulfur Radioisotopes; D004247:DNA