The effects of estradiol and progesterone on the concentration of striatal dopamine and tyramine in ovariectomized mice.
The concentration of homovanillic acid and p-tyramine in the female corpus striatum were increased after ovariectomy. The increases were reversed by chronic administration of estradiol benzoate and potentiated by progesterone. It is proposed that these changes are the consequence of concomitant variations in p-tyrosine availability.
D000818:Animals; D003342:Corpus Striatum / Q000187:drug effects / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism*; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D006719:Homovanillic Acid / Q000378:metabolism; D051379:Mice; D010052:Ovariectomy; D011374:Progesterone / Q000494:pharmacology*; D014439:Tyramine / Q000378:metabolism*
D011374:Progesterone; D004958:Estradiol; C028169:3-tyramine; D004298:Dopamine; D006719:Homovanillic Acid; D014439:Tyramine