[Comparative analysis of the malignancy of tumors in mice induced by 20-methylcholanthrene].
Malignancy of 13 cell cultures cultivated in vitro was studied. 11 cultures were induced by subcutaneous injection of 20-methylcholanthrene to 3 lines of mice. The malignancy was studied by transplantability, growth rate and metastasis formation after subcutaneous injection of a various cell number into normal and sublethally irradiated syngenic mice. A convenient model for studying the significance of certain immunological properties of tumour cells in determination of the malignancy was obtained.
D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D008748:Methylcholanthrene; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000473:pathology* / Q000532:radiotherapy; D013997:Time Factors; D014185:Transplantation, Isogeneic
D008748:Methylcholanthrene
Sravnitel'nyĭ analiz zlokachestvennosti opukholeĭ mysheĭ, indutsirovannykh 20-metilkholantrenom.