Hyperchloraemia: a non-specific finding in chronic renal failure.
To determine the prevalence of hyperchloraemia (plasma chloride concentration of 107 mmol/l or above) in chronic renal failure (CRF), we retrospectively analysed the acid-base and electrolyte status of 102 Italian and 53 English patients with impaired renal function. Hyperchloraemia was a frequent finding at all stages of CRF with a prevalence ranging from 30 to 50%. It was common both in tubulointerstitial nephropathies (45%) and chronic glomerulonephritis (39%). Hyperchloraemic patients were more acidotic than the normochloraemic.
D000136:Acid-Base Equilibrium; D001639:Bicarbonates / Q000097:blood; D002712:Chlorides / Q000097:blood*; D003928:Diabetic Nephropathies / Q000097:blood; D005921:Glomerulonephritis / Q000097:blood; D006801:Humans; D006977:Hypertension, Renal / Q000097:blood; D007676:Kidney Failure, Chronic / Q000097:blood*; D009395:Nephritis, Interstitial / Q000097:blood; D007690:Polycystic Kidney Diseases / Q000097:blood
D001639:Bicarbonates; D002712:Chlorides