[The role of membrane phospholipids in oxidative phosphorylation. A hypothesis of LC-coupling].
The role of lipid (pentadienyl) radicals and Mitchell's "C-elements" was analyzed. The function of the "C-elements" is necessary, but not enough for coupling of oxidation and phosphorylation. It was proposed that oxidative phosphorylation in the mitochondria membrane is the result of a direct coupling, involving participation of the "LC-elements" (where L and C reflect the inductive and capacitive character of the transformation device). The "L-elements" (the short pi-system) are lipid (pentadienyl) radicals formed in polyunsaturated fatty acids of phospholipids.
D000255:Adenosine Triphosphate / Q000096:biosynthesis; D055598:Chemical Phenomena; D002621:Chemistry; D004579:Electron Transport; D005609:Free Radicals; D008563:Membrane Lipids / Q000378:metabolism*; D008928:Mitochondria / Q000378:metabolism; D008954:Models, Biological; D010085:Oxidative Phosphorylation; D010743:Phospholipids / Q000378:metabolism*
D005609:Free Radicals; D008563:Membrane Lipids; D010743:Phospholipids; D000255:Adenosine Triphosphate
O roli membrannykh fosfolipidov v okislitel'nom fosforilirovanii. Gipoteza LC-sopriazheniia.