title: Histocompatibility in Italian couples with recurrent spontaneous abortions of unknown origin and with normal fertility.
abstract: We investigated HLA antigen and haplotype frequencies in 47 couples with primary recurrent abortions of unknown origin, in 65 fertile couples, and in a control panel of 98 males and 92 females. A significant increase of HLA-B17 was found in abortion couples in comparison with fertile couples. No difference between abortion and control fertile couples was observed regarding HLA sharing.
mesh_terms: D000026:Abortion, Habitual / Q000235:genetics / Q000276:immunology*; D000328:Adult; D005260:Female; D005298:Fertility; D005787:Gene Frequency; D006680:HLA Antigens / Q000235:genetics*; D015235:HLA-B Antigens; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D011247:Pregnancy
chemical_list: D006680:HLA Antigens; D015235:HLA-B Antigens; C037449:HLA-B17 antigen