title: Tuberculosis of the knee.
abstract: Ninety-eight cases of tuberculosis of the knee (85 adults and 13 children), treated by one or other of the authors, were reviewed. 70% of the patients presented an advanced stage of destructive disease, but 30% were seen at the stage of synovitis. A proven diagnosis was obtained in 88 out of 98 cases. In the majority, treatment was standardised with 6 to 12 months of chemotherapy and plaster immobilisation in order to prevent or correct a deformity. Arthrodesis was only undertaken for disabling deformity after conservative management (16 cases). Response to chemotherapy was favourable in 78 followed-up patients. Five relapses occurred between the 12th and 24th month. The functional results ranged from full normal recovery to spontaneous fusion or arthrodesis. The results were related to the stage of the disease at the time when treatment was started.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007103:Immobilization; D007538:Isoniazid / Q000627:therapeutic use; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D011718:Pyrazinamide / Q000627:therapeutic use; D011859:Radiography; D012293:Rifampin / Q000627:therapeutic use; D013307:Streptomycin / Q000627:therapeutic use; D014394:Tuberculosis, Osteoarticular / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
chemical_list: D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin