Gas chromatography of amino acids in urine and haemofiltrate.
Capillary gas chromatography of amino acid derivatives obtained from biological material shows a large number of previously unknown constituents. The profiles of amino acids obtained from urine of healthy individuals and haemofiltrate of uraemic patients indicate that haemofiltration removes some amino acids to a considerably higher extent from uraemic patients than the kidney does from healthy persons. For instance, if haemofiltration is required three times a week, an approximately ten-fold amount of the essential amino acid methionine and a forty-fold amount of the essential amino acid leucine is lost compared to their excretion in urine by a healthy individual over the same period.
D000596:Amino Acids / Q000032:analysis* / Q000097:blood / Q000652:urine; D001769:Blood; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D014462:Ultrafiltration; D014511:Uremia / Q000097:blood / Q000652:urine
D000596:Amino Acids