Electrn microscopic observations on virus-like particles associated with SH antigen.
The structural aspects of SH antigen-containing particles were investigated. These studies confirmed the existence of a large spherical particle (ca. 43 nm) and smaller (ca. 20 nm) rod- and sphere-shaped particles. The large particle consists of an outer and inner membrane and a core of "nucleic acid" as seen by positive staining techniques. The outer membrane of the large particle appears to be similar to that of the 20-nm diameter spheres and rods known to possess the SH antigen.
D000208:Acute Disease; D000941:Antigens; D002353:Carrier State / Q000276:immunology / Q000382:microbiology; D002908:Chronic Disease; D006509:Hepatitis B / Q000276:immunology / Q000382:microbiology; D006515:Hepatitis B virus / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D008854:Microscopy, Electron; D010772:Phosphotungstic Acid; D011196:Potassium Permanganate; D013194:Staining and Labeling; D014501:Uranium
D000941:Antigens; D011196:Potassium Permanganate; D010772:Phosphotungstic Acid; D014501:Uranium