title: [Diagnostic significance of determining the blood content of lactic and uric acids in chronic liver lesions of alcoholic and viral etiologies].
abstract: The concentration of lactic and uric acids in blood serum was measured in 115 patients with chronic liver lesions of virus (30 patients) and alcoholic (85 patients) etiology. The highest rise of lactic and uric acid concentrations was recorded in patients with alcoholic hepatitis and active alcoholic liver cirrhosis. The blood concentration of lactic and uric acids in alcoholic hepatopathy increased in parallel with an increment of the gravity of the pathological process, being the highest in patients with alcoholic hepatitis (lactic acid) and liver cirrhosis associated with the edematous ascites syndrome (uric acid). In inactive liver cirrhosis of alcoholic etiology, the concentrations of lactic and uric acids tended toward reduction, however, they were significantly higher than in the group of patients with virus liver lesions. Normal or negligible rises in the content of lactic and uric acids were seen in the groups of patients with chronic liver diseases of virus etiology. It is concluded that the measurement of the content of lactic and uric acids plays a diagnostic part in different patterns of alcoholic hepatopathies.
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006519:Hepatitis, Alcoholic / Q000097:blood / Q000175:diagnosis; D006521:Hepatitis, Chronic / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D008103:Liver Cirrhosis / Q000097:blood / Q000175:diagnosis*; D008108:Liver Diseases, Alcoholic / Q000097:blood / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D014527:Uric Acid / Q000097:blood*
chemical_list: D007773:Lactates; D014527:Uric Acid; D019344:Lactic Acid
vernacular_title: Diagnosticheskoe znachenie opredeleniia soderzhaniia molochnoĭ i mochevoĭ kislot v krovi pri khronicheskikh porazheniiakh pecheni alkogol'noĭ i virusnoĭ étiologii.