Sex differences in perceiving analgesic drug effects as measured by subjective pain ratings: a concealed signal detection theory analysis.
In a study using metamizole and placebo as equivalents of a strong and a weak stimulus in a signal detection device female headaches patients show better ability to discriminate the two drug stimuli than males, whereas there is no significant effect with respect to response bias.
D000328:Adult; D000632:Aminopyrine / Q000031:analogs & derivatives*; D004177:Dipyrone / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006261:Headache / Q000188:drug therapy* / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012684:Sensory Thresholds; D012718:Set, Psychology; D012737:Sex Factors
D000632:Aminopyrine; D004177:Dipyrone