Densitometric analysis of scans: important sources of artefact.
Computed tomography (CT) research in psychiatry often relies on the assessment of minor structural changes. Recently, it has come to encompass changes in regional brain X-ray absorption density. The artefacts prone to be encountered in density measurements are reviewed, and illustrated by a series of studies carried out using a CT 1010 scanner. They are shown to be more important than hitherto assumed in the interpretation of CT scan research.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000000981:diagnostic imaging*; D001921:Brain / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012886:Skull / Q000033:anatomy & histology; D013696:Temperature; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000592:standards