[Interaction of the M protein of the wild-type fowl pest virus and its ts-mutant with the ribonucleoprotein of the fowl pest virus in vitro].
The extent of inhibition of transcription realized in vitro by fowl plague virus (FPV) ribonucleoprotein (RNP) upon the addition of M protein isolated from FPV virions does not depend on nonionic detergent concentration in the reaction medium but does depend greatly on NaCl concentration. The highest inhibition of transcription is observed at a low ionic strength (0.02 M NaCl); inhibition is completely eliminated by increasing NaCl concentration to 0.3 M. When M protein isolated from FPV virions with ts mutation of M protein is added to RNP, addition to the system of 0.3 M NaCl decreases transcription inhibition but does not eliminate it completely.
D012321:DNA-Directed RNA Polymerases / Q000378:metabolism; D003902:Detergents / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D009980:Influenza A virus / Q000187:drug effects / Q000378:metabolism*; D009154:Mutation; D017830:Octoxynol; D011092:Polyethylene Glycols / Q000494:pharmacology; D012261:Ribonucleoproteins / Q000037:antagonists & inhibitors / Q000378:metabolism*; D012965:Sodium Chloride / Q000494:pharmacology; D014158:Transcription, Genetic / Q000187:drug effects; D014763:Viral Matrix Proteins; D014764:Viral Proteins / Q000378:metabolism*
D003902:Detergents; D012261:Ribonucleoproteins; D014763:Viral Matrix Proteins; D014764:Viral Proteins; D011092:Polyethylene Glycols; D012965:Sodium Chloride; D017830:Octoxynol; C010615:Nonidet P-40; D012321:DNA-Directed RNA Polymerases
Vzaimodeĭstvie belka M virusa chumy ptits dikogo tipa i ts-mutanta s ribonukleoproteidom virusa chumy ptits in vitro.