Life-threatening intracranial hypertension in Reye's syndrome treated with intravenous thiopentone.
A patient with Reye syndrome is described in whom cerebral perfusion pressure was reduced to less than 5 mmHg with loss of EEG activity. The intravenous administration of thiopentone reduced intracranial pressure and improved cerebral perfusion pressure with restoration of EEG and full recovery.
D004569:Electroencephalography; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D007427:Intracranial Pressure / Q000187:drug effects; D008297:Male; D011559:Pseudotumor Cerebri / Q000188:drug therapy* / Q000209:etiology; D012202:Reye Syndrome / Q000150:complications* / Q000188:drug therapy; D013874:Thiopental / Q000008:administration & dosage / Q000627:therapeutic use*
D013874:Thiopental