Efficacy of clorsulon and albendazole against Fascioloides magna in naturally infected white-tailed deer.
The efficacy of clorsulon and of albendazole against Fascioloides magna were evaluated in 36 naturally infected white-tailed deer (Odocoileus virginianus) in southern Texas. A single oral dose of clorsulon suspension (12 to 30 mg/kg of body weight; mean = 24 mg/kg) was given to each deer and killed 153 (92%) of 167 mature flukes and 4 (80%) of 5 immature flukes recovered at necropsy. A single oral dose of albendazole paste (17 to 46 mg/kg; mean = 26 mg/kg) was given to each deer and killed 148 (89%) of 167 mature flukes and 4 (67%) of 6 immature flukes recovered at necropsy. In 82 nontreated control deer, 271 live flukes were recovered; dead flukes were not recovered.
D015766:Albendazole; D000828:Animal Population Groups / Q000469:parasitology*; D000818:Animals; D000835:Animals, Wild / Q000469:parasitology*; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D003670:Deer / Q000469:parasitology*; D005213:Fascioloidiasis / Q000188:drug therapy*; D008099:Liver / Q000469:parasitology; D013424:Sulfanilamides / Q000627:therapeutic use*; D013781:Texas
D000871:Anthelmintics; D001562:Benzimidazoles; D013424:Sulfanilamides; C015675:clorsulon; D015766:Albendazole