Non-Hodgkin's lymphoma of the skin associated with chronic limb lymphoedema.
Cutaneous non-Hodgkin's lymphoma developed within a leg affected by chronic lymphoedema. The lymphoedema had followed radiotherapy to bony metastases from a carcinoma of the prostate. Eighteen months after the development of the cutaneous tumours, extracutaneous involvement by the lymphoma became apparent. This is the second report of a non-Hodgkin's lymphoma appearing within a lymphoedematous limb. The possible reasons for such an unusual localization are discussed. Our case report illustrates that cutaneous tumours other than lymphangiosarcomas may localize to a lymphoedematous limb and clinically simulate the Stewart-Treves syndrome.
D000368:Aged; D001859:Bone Neoplasms / Q000532:radiotherapy / Q000556:secondary; D002908:Chronic Disease; D006801:Humans; D007866:Leg; D008209:Lymphedema / Q000150:complications* / Q000209:etiology; D008223:Lymphoma / Q000150:complications* / Q000473:pathology; D008297:Male; D011878:Radiotherapy / Q000009:adverse effects; D012878:Skin Neoplasms / Q000150:complications*