Malignant melanoma appearing in a post-mastectomy lymphedematous arm: a novel association of double primary tumors.
The association of a malignant melanoma appearing as an additional primary tumor in the swollen arm adjacent to a mastectomy for breast cancer is reported. A review of the literature revealed only one similar patient previously reported. In both patients, the melanoma and its metastasis were restricted to the lymphedematous arm, appeared 10 years post-mastectomy, and responded to therapy. The similarity to Stewart-Treves syndrome is emphasized. It is suggested that nevi developing in the lymphedematous arm post-mastectomy should be carefully monitored and excised early whenever indicated.
D001132:Arm; D001943:Breast Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D008209:Lymphedema / Q000150:complications* / Q000175:diagnosis; D008408:Mastectomy; D008545:Melanoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000150:complications* / Q000175:diagnosis