title: Electroencephalographic findings in workers exposed to benzene.
abstract: Preventive EEG examination was carried out in 40 workers significantly exposed to benzene. The EEG findings were compared with those of a control group of 48 healthy persons, a group of 110 workers significantly exposed to toluene and xylene and a group of 236 workers exposed to vinyl chloride. The individuals exposed to benzene exhibited 22.5% of abnormal and 45% threshold findings, the abnormalities being episodic, diffuse or a combination of the two. The effect of benzene entailed a frequent (32.5%) occurrence of a characteristic frequency lability. Sleep phenomena were found in a total of 60% cases (37.5% cases reached stage 1 B3 while 15% reached stage 2 according to Roth [14]). The rapid onset of deeper sleep stages (in 30% cases) is considered typical for benzene exposure. The photic driving response often had an extended frequency range (a total of 61.1%, to beta frequencies only in 30.55%, to both beta and theta frequencies also in 30.55% of cases). The different EEG features characteristic of the neurotoxic action of various types of organic solvents make possible a more efficient diagnostics of the effects of these chemicals on the CNS.
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D001554:Benzene / Q000633:toxicity*; D001921:Brain / Q000187:drug effects*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012890:Sleep / Q000187:drug effects; D014050:Toluene / Q000633:toxicity; D014752:Vinyl Chloride / Q000633:toxicity; D014992:Xylenes / Q000633:toxicity
chemical_list: D000395:Air Pollutants, Occupational; D014992:Xylenes; D014050:Toluene; D001554:Benzene; D014752:Vinyl Chloride