title: [Humoral factors of general and local immunity in diabetes mellitus].
abstract: Considerable changes in the humoral factors of the general and local immunity were revealed during examination of 53 patients. A raised IgA and IgM level and a lowered titer of normal antibodies to antitoxins of diphtheria and tetanus and to staphylococcus antigen were revealed in the patients' blood. The content for IgG, lysozyme and normal antibodies to the antigens of dysentery and whooping cough was normal. A significant rise of the level of IgA, IgG, titers of normal antibodies and a decrease in the lysozyme activity were observed in the saliva.
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D003924:Diabetes Mellitus, Type 2 / Q000276:immunology*; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000276:immunology
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: [Sostoianie gumoral'nykh faktorov obshchego i mestnogo immuniteta pri sakharnom diabete.