title: Chemotherapy of experimental Besnoitia besnoiti infection in rabbits.
abstract: Rabbits were infected with a bovine strain of Besnoitia besnoiti parasites derived from VERO cell cultures. Oxytetracycline, given at 30 mg/kg i.m. simultaneously with infection, prevented the development of orchitis. The controls received no treatment. All infected animals showed a transient febrile reaction. It is concluded that oxytetracycline has some therapeutic potential against Besnoitia besnoiti and that rabbits are suitable models for therapeutic trials.
mesh_terms: D000818:Animals; D008297:Male; D009920:Orchitis / Q000517:prevention & control / Q000662:veterinary; D010118:Oxytetracycline / Q000627:therapeutic use*; D011528:Protozoan Infections / Q000188:drug therapy; D011529:Protozoan Infections, Animal; D011817:Rabbits
chemical_list: D010118:Oxytetracycline