[Effect of electrostimulation of the dorsolateral funiculus of the spinal cord on changes in the cardiac rhythm in acute myocardial ischemia].
The experiments were carried out on inbred white male rats. Cardiac rhythm changes revealed in acute myocardial ischemia under conditions of electrostimulation (ES) of descending sympathicoinhibitory pathways, constituting part of spinal dorsolateral funiculi (DLF) were studied. 10-min stimulation of DLF, started immediately after ligation of the left coronary artery, checked the development of severe cardiac arrhythmia, or considerably weakened the already existing one. The data obtained substantiate the assumption that the onset of cardiac arrhythmia in acute ischemia is associated with the involvement of sympathic preganglionic neurons into the pathologic system, which may be suppressed by the activation of the functionally opposite systems.
D000208:Acute Disease; D000818:Animals; D003327:Coronary Disease / Q000503:physiopathology*; D003331:Coronary Vessels / Q000502:physiology; D004558:Electric Stimulation / Q000379:methods; D006339:Heart Rate; D008026:Ligation; D008297:Male; D009433:Neural Inhibition; D051381:Rats; D013116:Spinal Cord / Q000502:physiology*; D013997:Time Factors
Vliianie élektrostimuliatsii dorsolateral'nogo kanatika spinnogo mozga na izmeneniia ritma serdtsa pri ostroĭ ishemii miokarda.