[Dyskinesia as a complication of the treatment of Parkinson disease with L-dopa--clinical observations].
The incidence of drug-induced dyskineses was evaluated in a group of 131 patients with Parkinson's disease on long-term treatment with L-DOPA preparations and the relationships were sought for between this incidence, and age of the patient at the onset of the disease and duration of treatment. Drug-induced dyskineses were observed in 79 (60%) patients. It was observed that their incidence was greater in patients with disease onset at a younger age. The mean age of disease onset in cases with dyskinesis development was nearly 10 years lower than the mean age of disease onset in those who had no dyskineses. In most cases of dyskinesis it developed already in the first year of treatment.
D000328:Adult; D000367:Age Factors; D000368:Aged; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy*; D013997:Time Factors
D007980:Levodopa
Dyskinezy jako powikłlanie leczenia preparatami L-dopa terapii choroby Parkinsona--obserwacje kliniczne.