Assignment of the mouse alpha A-crystallin structural gene to chromosome 17.
alpha A2-crystallin is one of the major water-soluble proteins of the mammalian lens. Using a cloned cDNA probe coding for mouse alpha A2-crystallin and Southern blot hybridization, DNA isolated from a panel of somatic cell hybrids prepared from mouse fibroblasts or mouse spleen cells fused with Chinese hamster fibroblasts was probed to determine the chromosomal localization of the alpha A2-crystallin structural gene. We have located this gene on mouse chromosome 17.
D000818:Animals; D002460:Cell Line; D002874:Chromosome Mapping; D006224:Cricetinae; D003412:Cricetulus; D003459:Crystallins / Q000235:genetics*; D004270:DNA, Circular; D005796:Genes; D006822:Hybrid Cells; D051379:Mice / Q000235:genetics*; D008807:Mice, Inbred BALB C
D003459:Crystallins; D004270:DNA, Circular