[Development of olfactory epithelial grafts in the anterior chamber of the eye].
Olfactory epithelium of newborn rats was transplanted into the anterior eye chamber of the adult rat. Within 6-8 weeks the transplants increased in weight by a factor of 20-50. Morphological analysis has shown the cells similar to olfactory sensory neurones in the grafts. Electroolfactograms obtained with n-amyl acetate and camphor had the amplitude of about three times less and the duration of about 8-10 times more than those from the normal olfactory epithelium at the same concentration of stimuli. Within six hours after 3H-beta-alanine had been introduced into the anterior eye chamber, 72% of the label were present in the carnosine fraction. The data obtained suggest that olfactory sensory neurones appear in the olfactory epithelium grafts into the anterior eye chamber.
D000818:Animals; D000831:Animals, Newborn; D000867:Anterior Chamber; D002164:Camphor / Q000494:pharmacology; D002336:Carnosine / Q000032:analysis / Q000096:biosynthesis; D004594:Electrophysiology; D004848:Epithelium / Q000033:anatomy & histology / Q000187:drug effects / Q000637:transplantation; D005260:Female; D006085:Graft Survival / Q000187:drug effects; D008297:Male; D009831:Olfactory Mucosa / Q000033:anatomy & histology / Q000187:drug effects / Q000637:transplantation*; D000439:Pentanols / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D000439:Pentanols; D002164:Camphor; D002336:Carnosine; C005716:amyl acetate
Razvitie transplantatov oboniatel'nogo épiteliia v peredeneĭ kamere glaza.