Effect of food on porcine gut regulatory peptides in arterial and portal venous blood.
The concentrations of gut regulatory peptides were monitored simultaneously in the portal and arterial circulations of 8 healthy conscious swine in the fasted state and after a standard mixed meal. The sampling was achieved via chronic cannulations of these two vessels. Portal/arterial differences of insulin and glucagon were similar to those previously described, indicating the importance of hepatic extraction of these two hormones. Portal/arterial differences for the gastrointestinal regulatory peptides were relatively small, however, and the liver is unlikely to be of major importance in the metabolism of these peptides.
D000818:Animals; D001158:Arteries / Q000378:metabolism; D004064:Digestive System / Q000378:metabolism*; D005260:Female; D005502:Food; D005768:Gastrointestinal Hormones / Q000097:blood*; D008297:Male; D011169:Portal Vein / Q000378:metabolism; D013552:Swine; D013997:Time Factors
D005768:Gastrointestinal Hormones