[Effect of L-lysine-alpha-oxidase on the cell cycle kinetics of cultured Burkitt's lymphoma cells].
L-lysine-alpha-oxidase from Trichoderma sp. fungi inhibits the synthesis of DNA, RNA and protein in cultivated cells of the Burkitt lymphoma (strain P3HRj) in vitro, which results in the blocking of the cells' transfer from phase S to phase G2/M of the mitotic cycle.
D000594:Amino Acid Oxidoreductases / Q000633:toxicity*; D002051:Burkitt Lymphoma / Q000378:metabolism / Q000473:pathology*; D002453:Cell Cycle / Q000187:drug effects; D002478:Cells, Cultured; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006801:Humans; D009363:Neoplasm Proteins / Q000096:biosynthesis; D012334:RNA, Neoplasm / Q000096:biosynthesis; D013997:Time Factors; D014242:Trichoderma / Q000201:enzymology
D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D000594:Amino Acid Oxidoreductases; C041123:L-lysine oxidase
Vliianie L-lizin-al'fa-oksidazy na kinetiku kletochnogo tsikla kul'tiviruemykh kletok limfomy Berkitta.