[Plasma lipoprotein levels and functional status of thrombocytes in patients with ischemic heart disease during treatment with essential phospholipids].
Variations in platelet aggregation activity before and after the control of lipid metabolism with lecithin linoleate (essential preparation, 1800 mg EPL daily) were examined in coronary patients with pronounced hyperlipidemia. A considerable change was noted in the ratios of LP fractions, that is, rising HDLP in the presence of decreasing total plasma lipids, Changes in plasma lipid composition were accompanied with a reduction of platelet aggregation activity that persisted for 3 months following the discontinuation of the drug. Correlation and regression analyses of relationships between platelet aggregation and HDLP levels were carried out.
D000328:Adult; D003327:Coronary Disease / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D006951:Hyperlipoproteinemias / Q000150:complications / Q000188:drug therapy*; D008055:Lipids / Q000097:blood; D008074:Lipoproteins / Q000097:blood; D008075:Lipoproteins, HDL / Q000097:blood*; D008875:Middle Aged; D010713:Phosphatidylcholines / Q000627:therapeutic use*; D010974:Platelet Aggregation
D008055:Lipids; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D010713:Phosphatidylcholines; C011246:essential 303 forte
Uroven' lipoproteidov v plazme krovi i funktsional'noe sostoianie trombotsitov u bol'nykh ishemicheskoĭ bolezn'iu serdtsa pri terapii éssentsial'nymi fosfolipidami.