[Nature of the diabetogenic factor of blood plasma in clinical and experimental diabetes].
A homogeneous diabetogenic factor (HDF), an albumin with the molecular mass of 60 000 daltons, was isolated from the blood of people and animals with diabetes mellitus. An i.v. injection of HDF to intact rats resulted in a prolonged and stable hyperglycemia. HDF hyperglycemic activity was completely blocked in the recipients by the injection of appropriate heparin doses.
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003920:Diabetes Mellitus / Q000097:blood / Q000209:etiology*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000209:etiology*; D006801:Humans; D006943:Hyperglycemia / Q000097:blood / Q000209:etiology; D008297:Male; D008970:Molecular Weight; D051381:Rats; D012709:Serum Albumin / Q000302:isolation & purification / Q000494:pharmacology*
D001786:Blood Glucose; D012709:Serum Albumin
Priroda "diabetogennogo" faktora plazmy krovi pri klinicheskom i éksperimental'nom diabete.