Biochemical studies of apparently 'healthy' blood donors with reference to liver function tests and immunoglobulins.
Liver function tests and immunoglobulin features of apparently 'healthy' blood donors were studied. Twenty-one (9.5%) subjects with HBsAg were observed. These subjects were found to have significantly higher mean and standard deviation of total serum bilirubin, alanine and aspartate aminotransferase levels than those of a randomly selected HBsAg-negative group. Serum urea was significantly lower (p less than 0.01) in the HBsAg-positive cases. Total serum IgE (IU/ml) was significantly higher in the HBsAg-positive cases (p less than 0.01). Comparison of laboratory findings of these cases and active hepatitis HBsAg-positive subjects showed that there were more elevated abnormalities in the latter.
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D001782:Blood Donors; D001798:Blood Proteins / Q000032:analysis; D003404:Creatinine / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D008111:Liver Function Tests; D012016:Reference Values; D014508:Urea / Q000097:blood
D001798:Blood Proteins; D006514:Hepatitis B Surface Antigens; D007136:Immunoglobulins; D014508:Urea; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin