Papaverine therapy in atopic dermatitis.
Papaverine hydrochloride taken by mouth in doses of 100 mg four to six times daily or in 150-mg timed-release capsules two or three times daily is often effective in significantly decreasing itching in patients with atopic dermatitis. When used orally, as described here, it does not appear to have beneficial effects in other itchy dermatoses. It should be used as adjuvant treatment in combination with other accepted forms of therapy, since it alone cannot reverse the chronic skin changes brought about by months or years of scratching and rubbing.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D006801:Humans; D010208:Papaverine / Q000009:adverse effects / Q000627:therapeutic use*; D010726:Phosphodiesterase Inhibitors / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D010726:Phosphodiesterase Inhibitors; D010208:Papaverine