title: [Changes in the hemostatic system in patients with ischemic heart disease after isovolemic hemodilution].
abstract: To specify indications for isovolumic hemodilution, hemostatic parameters (fibrinogen, soluble fibrin, fibrin decomposition products, platelet aggregation, thromboelastograms) were compared with clinical manifestations of coronary heart diseases (CHD) and coronarographic and bicycle-ergometric findings in 41 coronary patients. The increased blood viscosity syndrome was found in 63% of the patients. Isovolumic hemodilution was performed to control the detected disorders in 17 patients. Hemodilution was shown to be an effective means of controlling hemostatic disorders in coronary patients, hemostatic normalization being accompanied with clinical improvement in part of the cases.
mesh_terms: D000328:Adult; D000368:Aged; D001777:Blood Coagulation; D001809:Blood Viscosity; D003327:Coronary Disease / Q000097:blood / Q000628:therapy*; D005080:Exercise Test; D005260:Female; D005337:Fibrin / Q000032:analysis; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006438:Hemodilution; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; D005337:Fibrin; D005340:Fibrinogen
vernacular_title: Izmeneniia v sisteme gemostaza u bol'nykh ishemicheskoĭ bolezn'iu serdtsa pri izovolemicheskoĭ gemodiliutsii.