title: Effects of withdrawal from long-term nicotine gum use.
abstract: A small proportion of smokers who stop smoking with the aid of nicotine chewing gum continue to use the gum for more than a year. This study shows that when these people abstain from nicotine gum use they experience withdrawal symptoms similar to those found during cigarette withdrawal, including increased irritability, difficulty in concentrating and a drop in heart rate.
mesh_terms: D000328:Adult; D002638:Chewing Gum / Q000009:adverse effects*; D005260:Female; D006339:Heart Rate; D006801:Humans; D009538:Nicotine / Q000009:adverse effects*; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
chemical_list: D002638:Chewing Gum; D009538:Nicotine