title: [New approaches to studying the functional relations of the gastrointestinal tract with the endocrine glands].
abstract: A study was made of changes of the content of hormones (gastrin, insulin, glucagon, triodonthyronine, thyroxine, thyrotrophin, somatotrophin, adrenocorticotrophin and hydrocortisone) under the influence of standard food load in 166 patients with GIT diseases (gastric ulcer, duodenal ulcer, chronic anacid gastritis and chronic enteritis). Forty-three healthy persons entered the control group. Hormones were determined in the peripheral blood by radioimmunoassay. Taking food in healthy persons was shown to cause the stimulation of the secretion of most hormones. To elucidate the mechanisms of hormonal shifts after food load, hormones were also studied after per os intake of solutions with different pH. Disorders of postprandial reactions of the endocrine system which were specific for these nosological forms, were revealed in GIT diseases. The results of the study are of interest in view of new approaches to functional interrelationships of the GIT with endocrine glands.
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004044:Dietary Proteins / Q000008:administration & dosage; D004064:Digestive System / Q000503:physiopathology*; D004702:Endocrine Glands / Q000503:physiopathology*; D005247:Feeding Behavior / Q000502:physiology; D005260:Female; D005767:Gastrointestinal Diseases / Q000503:physiopathology; D006728:Hormones / Q000097:blood; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D013997:Time Factors
chemical_list: D004044:Dietary Proteins; D006728:Hormones
vernacular_title: Novye podkhody k izucheniiu funktsional'nykh sviazeĭ zheludochno-kishechnogo trakta s zhelezami vnutrenneĭ sekretsii.