Epidemiology and serology of Giardia lamblia in a developing country: Bangladesh.
The age-specific prevalence of Giardia lamblia was determined in two Bangladeshi villages and malnourished children in hospital in Dhaka City. Age-specific acquisition rates, the duration of infection and age-specific sero-positivity to (immunofluorescent assay) G. lamblia trophozoites were determined. Infection was acquired early (less than one year) and in 16% of infected children persisted for longer than three months. Prevalence was higher in 5 to 10-year-old village children (21%) and one to five-year-old malnourished children (51%). Over 40% of the children much less than 7 years acquired G. lamblia within 18 months; acquisition rates did not change with age. Positive antibody titres were acquired between six months and one year and the prevalence of sero-positivity remained high in all age groups No association was found between positive antibody titres and positive stool examinations. In developing countries serum antibodies are useful epidemiologically, but are not diagnostic in the individual patient.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000906:Antibodies / Q000032:analysis; D001459:Bangladesh; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D004404:Dysentery, Amebic / Q000150:complications; D005260:Female; D005873:Giardiasis / Q000150:complications / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male; D009748:Nutrition Disorders / Q000150:complications
D000906:Antibodies