[Ultrastructural relations between monoaminergic and peptidergic systems in the hypothalamus. Radioautographic approach and immunocytochemical binding in the arcuate nucleus and suprachiasmatic nucleus in the rat].
This paper deals with the cytological substratum for interactions between serotonin and dopamine, pro-opiomelanocortin (POMC) or vasoactive intestinal peptide (VIP) within the hypothalamus. Using a combination of radioautography and immunocytochemistry on the same thin sections in the rat, direct appositions not involving synaptic specializations were demonstrated between serotoninergic terminals and dopaminergic as well as POMC neurons in the arcuate nucleus. In the suprachiasmatic nucleus, quantitative data have indicated that VIP neurons constitute a preferential synaptic target for serotoninergic afferents. The functional implications of these results are discussed.
D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000648:ultrastructure*; D001345:Autoradiography; D004298:Dopamine / Q000378:metabolism; D006651:Histocytochemistry; D011333:Pro-Opiomelanocortin / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism; D013493:Suprachiasmatic Nucleus / Q000648:ultrastructure*; D014660:Vasoactive Intestinal Peptide / Q000032:analysis
D012701:Serotonin; D014660:Vasoactive Intestinal Peptide; D011333:Pro-Opiomelanocortin; D004298:Dopamine
Relations ultrastructurales entre systèmes monoaminergiques et peptidergiques dans l'hypothalamus. Approche radioautographique et immunocytochimique couplée dans le noyau arqué et le noyau suprachiasmatique du rat.