Leucocyte esterase-nitrite screening method for pyuria and bacteriuria.
The value of the one minute leucocyte esterase-nitrite chemical strips as a screening procedure for detecting appreciable levels of pyuria and bacteriuria was assessed by comparison with microscopy and culture results. The likelihood that a negative leucocyte esterase result indicated less than 10 white cells/cu mm by microscopy (the negative predictive value), was 90.1% and that a negative nitrite result indicated less than 10(5) organisms/ml was 91.3%. There were many false positive results with both tests, however, and the overall predictive value of a positive leucocyte esterase or nitrite test, or both, was low. The leucocyte esterase-nitrite strip was neither sufficiently sensitive nor specific enough to be used as a cost effective method for screening urines in the laboratory.
D001437:Bacteriuria / Q000175:diagnosis*; D004950:Esterases / Q000032:analysis*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D007962:Leukocytes / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D009573:Nitrites / Q000032:analysis*; D011776:Pyuria / Q000175:diagnosis*; D011934:Reagent Strips
D009573:Nitrites; D011934:Reagent Strips; D004950:Esterases