title: Dietary intake in thyrotoxicosis before and after adequate carbimazole therapy; the impact of dietary advice.
abstract: Dietary intake, including actual nutrient and energy intake, was assessed in 21 successive thyrotoxic patients before and after adequate carbimazole therapy. Group A (10 subjects) received regular formal dietary advice whereas Group B (11 subjects) did not. An age and sex matched control group, comprising 23 normal individuals, was also studied. The mean energy intake of all the thyrotoxic subjects was significantly greater than that of the normal control group (P less than 0.0025). There was a greater overall reduction in the energy intake of Group A as compared with Group B (P less than 0.01) and the former gained less weight, when expressed as a percentage of pretreatment weight. The mean final weight of all the thyrotoxic subjects exceeded the mean ideal weight for the group, reflecting a degree of true obesity at this stage. The simple measure of incorporating dietary advice into the treatment programme of thyrotoxic patients will usually result in some reduction of energy intake, and thus weight gain, en route to euthyroidism.
mesh_terms: D000328:Adult; D002231:Carbimazole / Q000627:therapeutic use*; D004032:Diet; D002149:Energy Intake; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
chemical_list: D002231:Carbimazole