Sympathetic ophthalmia. An immunohistochemical study of epithelioid and giant cells.
There is controversy regarding the origin of the pigment-containing epithelioid cells in the uvea of eyes with sympathetic ophthalmia. The results of the present immunocytochemical study demonstrating the presence of muramidase and S-100 protein in these cells, and the binding of peanut lectin by the pigment-containing cells support the interpretation that the pigment-containing epithelioid cells and giant cells are of monocytic (histiocytic) origin. Our study also emphasizes the diverse functional capacity of these epithelioid cells.
D004848:Epithelium; D005123:Eye / Q000032:analysis / Q000473:pathology; D006801:Humans; D007120:Immunochemistry; D037102:Lectins / Q000032:analysis; D009113:Muramidase / Q000032:analysis; D009879:Ophthalmia, Sympathetic / Q000201:enzymology / Q000473:pathology*; D019887:Peanut Agglutinin
D037102:Lectins; D019887:Peanut Agglutinin; D009113:Muramidase