title: Fatty acid compositions of erythrocytes, mononuclear cells and blood plasma of patients with myotonic dystrophy.
abstract: Fatty acid compositions of erythrocyte membrane phospholipids including phosphatidylethanolamine subclasses, blood plasma and mononuclear cells of 8 patients with myotonic dystrophy (MyD) and 8 normal controls were analyzed by high performance liquid chromatography. Slight changes (decreased C18:2 and increased C16:0) in the fatty acid compositions of erythrocyte membrane glycerophospholipids and blood plasma lipids were observed in MyD. There was no significant difference in the fatty acid composition of mononuclear cells between MyD and normal controls. It seems that no essential defect exists in either the erythrocyte membrane fatty acid composition or the fatty acid metabolism itself in MyD.
mesh_terms: D000293:Adolescent; D000328:Adult; D002851:Chromatography, High Pressure Liquid; D004910:Erythrocyte Membrane / Q000032:analysis*; D005227:Fatty Acids / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008563:Membrane Lipids / Q000097:blood; D008875:Middle Aged; D009000:Monocytes / Q000032:analysis*; D009223:Myotonic Dystrophy / Q000097:blood*; D010714:Phosphatidylethanolamines / Q000097:blood; D012503:Saponins
chemical_list: D005227:Fatty Acids; D008563:Membrane Lipids; D010714:Phosphatidylethanolamines; D012503:Saponins