[Radiosensitivity of clonogenic granulocytic macrophage cell precursors in the bone marrow and spleen of tumor-bearing mice].
Clonogenic granulocytic macrophagal cells-precursors (CFU-DC) of bone marrow and spleen of intact C57Bl/6 mice and those inoculated subcutaneously with LLC tumor cells do not substantially differ in their radiosensitivity; the concentration of CFU-DC in the spleen markedly varies as tumor grows. The values of Do and extrapolation number n for CFU-DC of the bone marrow are 0.9-1.4 and 1.5-3.0 Gy, and of the spleen, 0.8-1.6 and 1.0-2.6 Gy, respectively.
D000818:Animals; D001853:Bone Marrow / Q000473:pathology*; D002470:Cell Survival / Q000528:radiation effects; D003037:Cobalt Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000473:pathology*; D014411:Neoplastic Stem Cells / Q000528:radiation effects*; D013154:Spleen / Q000473:pathology*
D003037:Cobalt Radioisotopes
Radiochuvstvitel'nost' klonogennykh granulotsitarno-makrofagal'nykh kletok-predshestvennikov, soderzhashchikhsia v kostnom mozge i selezenke mysheĭ-opukholenositeleĭ.