Diabetic serum stimulates the proliferation of endothelial cells in culture.
Pooled serum from insulin dependent or non-insulin dependent diabetics stimulated the proliferation of endothelial cells in culture. This potentiating effect was observed only during the growth phase, but not when confluency was reached. Both diabetic and control endothelial cells proliferated normally in control serum.
D001798:Blood Proteins / Q000494:pharmacology; D002455:Cell Division; D002478:Cells, Cultured; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000473:pathology; D004727:Endothelium / Q000166:cytology; D006133:Growth Substances / Q000494:pharmacology; D006801:Humans; D014471:Umbilical Veins / Q000166:cytology*
D001798:Blood Proteins; D006133:Growth Substances