title: Local immunotherapy for chronic respiratory allergic pathology with allergen aerosols. I. Treatment of allergic rhinitis.
abstract: For treatment of patients with chronic allergic rhinitis of pollen, dust, fungal and bacterial etiology two methods of specific therapy were employed. The first one consisted of projecting allergen aerosols into the nasal cavity on a special dosage schedule for a month or two; the second was the method of intradermal or subcutaneous injections of allergens. It was ascertained that local treatment has its advantages over a generally accepted method of injections. Good clinical effect combined with positive immunological shifts and decrease of nasal mucous membrane hypersensitivity to support this.
mesh_terms: D000336:Aerosols; D000485:Allergens / Q000008:administration & dosage / Q000627:therapeutic use*; D001419:Bacteria / Q000276:immunology; D004391:Dust; D005069:Evaluation Studies as Topic; D005658:Fungi / Q000276:immunology; D006801:Humans; D007167:Immunotherapy; D007271:Injections, Intradermal; D007279:Injections, Subcutaneous; D011058:Pollen / Q000009:adverse effects; D012221:Rhinitis, Allergic, Perennial / Q000628:therapy*
chemical_list: D000336:Aerosols; D000485:Allergens; D004391:Dust