Prognostic significance of transrectal fine-needle aspiration biopsy findings after orchiectomy for carcinoma of the prostate.
In 48 patients with prostatic carcinoma two types of cell patterns were found at fine-needle aspiration biopsy at follow-up 6 and 12 months after orchiectomy: (1) unmodified carcinoma cells or (2) carcinoma cells with regressive changes. Objective clinical regression at 36 months was significantly more frequent in patients with regressively transformed cancer cells at 6 and/or 12 months than in patients with unmodified carcinoma cells: 73 and 32%, respectively. Ten percent of the patients with regressively transformed carcinoma cells and 41% of the patients with unmodified cancer cells died of prostatic carcinoma. The cytologic findings at 6 and/or 12 months after orchiectomy is thus of importance for predicting the prognosis.
D000368:Aged; D001707:Biopsy, Needle; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009919:Orchiectomy; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*