Larvicidal effect of flubendazole on Angiostrongylus cantonensis in mice with various worm burdens.
Flubendazole given orally at 50 mg/kg to mice inoculated with 50, 250 or 500 larvae of Angiostrongylus cantonensis showed almost complete larvicidal effect, irrespective of the worm burden.
D000801:Angiostrongylus / Q000187:drug effects*; D000818:Animals; D001921:Brain / Q000469:parasitology; D005260:Female; D006801:Humans; D007814:Larva / Q000187:drug effects; D008463:Mebendazole / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D008681:Metastrongyloidea / Q000187:drug effects*; D051379:Mice; D008813:Mice, Inbred ICR; D009349:Nematode Infections / Q000188:drug therapy* / Q000469:parasitology
D008463:Mebendazole; C018945:flubendazole