Phytochemical investigation of Tabernaemontana crassa.
From the stembark of Tabernaemontana crassa the alkaloid ibogaine was isolated as the major component. Ibogaine showed activity against the gram-positive Bacillus subtilis. Conopharyngine was identified as one of the minor compounds.
D000470:Alkaloids / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002855:Chromatography, Thin Layer; D007050:Ibogaine / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000032:analysis*
D000470:Alkaloids; D007050:Ibogaine