SSPE: epidemiological and serological features in a series of cases recorded between 1975 and 1984.
A number of 632 new cases of subacute sclerosing panencephalitis (SSPE) could be detected during a 10-year survey. The continuous increase in the number of annual cases suggests a possible correlation with the changes induced in measles epidemiology by the initiation of compulsory vaccination. On the other hand, a comparison of epidemiological and serological characteristics revealed significant differences between the series of SSPE cases recorded in the period preceding and in that following measles vaccination.
D000367:Age Factors; D000418:Albumins / Q000134:cerebrospinal fluid; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D007223:Infant; D008458:Measles Vaccine / Q000276:immunology; D008459:Measles virus / Q000276:immunology; D012383:Romania; D012424:Rural Population; D012621:Seasons; D013344:Subacute Sclerosing Panencephalitis / Q000453:epidemiology* / Q000276:immunology; D014505:Urban Population
D000418:Albumins; D000914:Antibodies, Viral; D007074:Immunoglobulin G; D008458:Measles Vaccine