Creatine kinase, steroidogenesis and the developing ovarian follicle.
Creatine kinase activity was present throughout follicular development and luteinization in rat ovary. The activity of creatine kinase in ovary was about 1/4 that of brain and 1/15th that of heart. The ovary contained the same creatine kinase isoenzyme as brain, and the type did not change during follicular development. Creatine kinase was found to be concentrated in the steroidogenic thecal and luteal cells of the ovary. The activity of creatine kinase was stimulated 23% by choriogonadotropin in luteal tissue.
D000818:Animals; D003338:Corpus Luteum / Q000201:enzymology / Q000254:growth & development*; D003402:Creatine Kinase / Q000032:analysis*; D005260:Female; D006064:Gonadotropins, Equine / Q000494:pharmacology; D007527:Isoenzymes; D006080:Ovarian Follicle / Q000502:physiology; D010053:Ovary / Q000166:cytology / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013256:Steroids / Q000378:metabolism; D013480:Superovulation
D006064:Gonadotropins, Equine; D007527:Isoenzymes; D013256:Steroids; D003402:Creatine Kinase