title: The ovine bronchopulmonary lymph drainage pathways: a model to study pulmonary immune responses.
abstract: The lymph drainage pathways of all ovine bronchopulmonary segments (BPS) were traced following intrabronchial instillation of dyes and/or 125IUdR-labeled bacteria. The critical observation, relative to pulmonary immune apparatus, was the identification of at least three BPS-regional lymph node sets with nonoverlapping lymph drainage pathways: right cranial segment-cranial bronchial lymph node; left apical segment-caudal bronchial lymph node; and dorsal-basal, and accessory lobe segments-caudal mediastinal (caudal) lymph node. The efferent lymph drainage pathways from the pulmonary regional lymph nodes were also delineated. This anatomic information is being used to develop a model for studying the respective roles of intrapulmonary, regional, and systemic lymphoid tissues in pulmonary immune responsiveness.
mesh_terms: D000818:Animals; D001980:Bronchi / Q000033:anatomy & histology*; D004396:Coloring Agents; D005260:Female; D008168:Lung / Q000276:immunology*; D008198:Lymph Nodes / Q000033:anatomy & histology / Q000502:physiology; D008208:Lymphatic System / Q000033:anatomy & histology*; D008297:Male; D012756:Sheep
chemical_list: D004396:Coloring Agents