[Cutaneous vasculitis associated with chronic hepatitis: 2 cases].
2 cases of cutaneous vasculitis associated with chronic hepatitis and mixed cryoglobulinaemia are reported. Further studies revealed in the first case hypocomplementaemia and glomerulonephritis. The cutaneous lesions of this patient responded dramatically to plasma exchange whereas prednisolone 20 mg/day and azathioprine 50 mg/day for 10 months showed no effect. The second case (chronic active hepatitis with acute colitis) responded well to prednisolone and azathioprine. The cutaneous lesions (vascularitis) may be the only clinical symptom of a chronic hepatitis and the study of those cases sometimes allows an early diagnosis of renal failure to be made.
D001379:Azathioprine / Q000627:therapeutic use; D003449:Cryoglobulinemia / Q000150:complications*; D005260:Female; D005921:Glomerulonephritis / Q000150:complications; D006521:Hepatitis, Chronic / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D010951:Plasma Exchange; D011239:Prednisolone / Q000627:therapeutic use; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000209:etiology* / Q000628:therapy
D011239:Prednisolone; D001379:Azathioprine
Vasculite cutanée révélatrice d'une hépatite chronique: à propos de 2 cas.