Unexpected synergism between an alkylating analog of oxotremorine and soman.
D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001286:Atropine Derivatives / Q000494:pharmacology; D001831:Body Temperature / Q000187:drug effects; D001921:Brain / Q000201:enzymology; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism; D002800:Cholinesterase Inhibitors; D004357:Drug Synergism; D010095:Oxotremorine / Q000031:analogs & derivatives* / Q000633:toxicity; D010276:Parasympatholytics / Q000494:pharmacology / Q000633:toxicity*; D011760:Pyrrolidinones / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D012999:Soman / Q000633:toxicity*
D001286:Atropine Derivatives; D002800:Cholinesterase Inhibitors; D010276:Parasympatholytics; D011760:Pyrrolidinones; C003025:N-(4-(2-chloroethylmethylamino)-2-butynyl)-2-pyrrolidone; D010095:Oxotremorine; D001285:Atropine; C006649:methylatropine; D012999:Soman; D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase; D000110:Acetylcholinesterase