title: [2-Chloro-1-methylpyridinium iodide. A suitable reagent for peptide synthesis].
abstract: 2-Chloro-1-methylpyridinium iodide is a coupling reagent for peptide synthesis. By its use different peptides were synthesized with protected di- and trifunctional amino acids. While urethan-protected amino acids react free of racemization, the fragment condensation needs N-Hydroxysuccinimide, as shown by the Young test.
mesh_terms: D000596:Amino Acids; D055598:Chemical Phenomena; D002621:Chemistry; D007202:Indicators and Reagents; D010455:Peptides / Q000138:chemical synthesis*; D011726:Pyridinium Compounds; D013237:Stereoisomerism; D013388:Succinimides
chemical_list: D000596:Amino Acids; D007202:Indicators and Reagents; D010455:Peptides; D011726:Pyridinium Compounds; D013388:Succinimides; C048173:2-chloro-1-methylpyridinium; C001426:N-hydroxysuccinimide
vernacular_title: 2-Chlor-1-methylpyridiniumjodid. Ein geeignetes Kupplungsreagenz für Peptidsynthesen.