The relationship between Parkinson's disease and dementia. A study using proton NMR imaging parameters.
The value of the spin lattice relaxation time (T1) obtained during nuclear magnetic resonance imaging of the brain was studied in patients with idiopathic Parkinson's disease, with and without dementia. T1 increases significantly in the basal ganglia and cerebral white matter of the demented and non-demented groups. T1 of the cerebral white matter correlates with the severity of dementia.
D000368:Aged; D001921:Brain; D003704:Dementia / Q000150:complications / Q000175:diagnosis*; D005917:Globus Pallidus; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis*; D011699:Putamen; D013997:Time Factors