Identified GABAergic inhibitory motor neurons in the leech central nervous system take up GABA.
Physiologically identified inhibitory motor neurons in the leech central nervous system were double-labeled by intracellular injection of the dye Lucifer Yellow and gamma-amino-[3H]butyric acid ([3H]GABA) uptake to demonstrate that these inhibitory neurons are among the approx. 35 neurons per abdominal ganglion previously shown to take up GABA. GABA uptake into the inhibitory motor neurons is stimulated by electrical activity in the neurons.
D000200:Action Potentials; D000818:Animals; D002490:Central Nervous System / Q000378:metabolism / Q000502:physiology; D004594:Electrophysiology; D005456:Fluorescent Dyes; D005724:Ganglia / Q000378:metabolism; D007865:Leeches / Q000378:metabolism* / Q000502:physiology; D009046:Motor Neurons / Q000378:metabolism / Q000502:physiology; D009433:Neural Inhibition; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005456:Fluorescent Dyes; D005680:gamma-Aminobutyric Acid