title: [Assay of acenocoumarol (Sintrom) in the plasma by liquid chromatography].
abstract: Reversed-phase liquid chromatography was performed on C18 column using a pH 4 buffered water-methanol 45:55 (v/v) mobile phase and ultraviolet detection (307 nm). Warfarin was used as internal standard and dichloro-1,2 ethane as extraction solvent. The analytical recovery was greater than 98 p. cent. The within-day coefficient of variation (CV) was 5 p. cent, while the between day CV was 6.4 p. cent. The limit of detection was 0.02 mg/l.
mesh_terms: D000074:Acenocoumarol / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D006801:Humans
chemical_list: D000074:Acenocoumarol
vernacular_title: Dosage de l'acénocoumarol (Sintrom) dans le plasma par chromatographie en phase liquide.