title: [Carcinoma of the uterine cervix associated with pregnancy--analysis of 458 cases].
abstract: From 1958-1978, 458 patients with carcinoma of the cervix complicated with pregnancy were treated in our hospital. It comprised 4.3% of the total number of cervical carcinoma admitted for radiotherapy during the same period. In these patients, 112 cases were antenatal and 346 cases were postnatal. The five year survival rates were 56.2% and 44.7%, respectively, both being lower than that (69.4%) of nonpregnant patients. Statistics showed: 1. the earlier the period of pregnancy, the better the prognosis. 2. within six months postpartum, the earlier the treatment, the higher the survival rate. These results suggest that pregnancy has an unfavorable effect on cervical carcinoma. Irradiation treatment was essentially the same for patients who were pregnant or not. Termination of pregnancy, however, was a prerequisite. In the first trimester of pregnancy, spontaneous abortion with radiation was advocated. In the second and third trimesters of pregnancy, hysterotomy and removal of foetus for proper irradiation was done. Intracavitary irradiation was recommended before termination of pregnancy and postabortal or postpartum external radiation was started as early as possible in order to achieve more favorable results.
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000401:mortality / Q000532:radiotherapy*; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000532:radiotherapy*