Lipoid proteinosis presenting with neuropsychiatric manifestations.
Two patients with lipoid proteinosis are reported in whom paranoid symptoms were the presenting feature. Both had a long standing impairment of memory and bilateral medial temporal lobe calcification demonstrated by CT scan. Possible associations between the anatomical site of these lesions and the neuropsychiatric manifestations are discussed.
D000293:Adolescent; D000679:Amygdala / Q000473:pathology; D002114:Calcinosis / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D005260:Female; D006801:Humans; D008064:Lipidoses / Q000523:psychology*; D008065:Lipoid Proteinosis of Urbach and Wiethe / Q000473:pathology / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000473:pathology / Q000523:psychology*; D009483:Neuropsychological Tests; D010259:Paranoid Disorders / Q000473:pathology / Q000523:psychology*; D013702:Temporal Lobe / Q000473:pathology; D014057:Tomography, X-Ray Computed