Changes in neurons and interneural connections of the higher sections of the motor system in the progeny of alcoholized male and female rats.
We have studied the effects of long-term alcoholic intoxication of male and female rats on the structural development of the sensory motor cortex and the caudate nucleus in 21-day-old rats (their progeny). Using light microscopy and morphometry we observed a delay in the maturation of neurons and their dendrites, and also dystrophic changes in the nerve structures in the experimental animals. The morphological changes observed show that alcoholic intoxication of parents leads to negative effects on postnatal development of their progeny.
D000437:Alcoholism / Q000235:genetics* / Q000473:pathology; D000818:Animals; D002421:Caudate Nucleus / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D008098:Litter Size; D008297:Male; D009044:Motor Cortex / Q000473:pathology* / Q000648:ultrastructure; D009434:Neural Pathways / Q000473:pathology* / Q000648:ultrastructure; D009474:Neurons / Q000473:pathology* / Q000648:ultrastructure; D051381:Rats; D013003:Somatosensory Cortex / Q000473:pathology / Q000648:ultrastructure; D013997:Time Factors