Multicentric reticulohistiocytosis and Sjögren's syndrome.
A 66-year-old man with an 18-year history of cutaneous multicentric reticulohistiocytosis (MRH) developed a chronic destructive symmetrical arthritis and xerostomia. Biopsies of synovium and minor salivary glands established a diagnosis of MRH polyarthritis and lymphocytic infiltrative Sjögren's syndrome, respectively. Anti-Ro(SSA) antibody was present. Hypothyroidism was also identified. This report of Sjögren's syndrome in MRH may enlarge the spectrum of autoimmune diseases associated with MRH.
D000368:Aged; D001168:Arthritis / Q000150:complications; D001706:Biopsy; D006225:Hand / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D011859:Radiography; D012469:Salivary Glands / Q000473:pathology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000473:pathology; D013583:Synovial Membrane / Q000473:pathology