title: [Familial occurrence of Peutz-Jeghers syndrome and Crohn disease with manifestation of both diseases in the same patient].
abstract: This is the first communication on a coincidental manifestation of Peutz-Jeghers syndrome and Crohn's disease. In the index case polyposis was found at the age of eight and Crohn's disease was diagnosed at the age of 121/2 years. In this family, both the father and the eldest sister of the patient have a Peutz-Jeghers syndrome. The cousin of the mother also has Crohn's disease. The prognosis of a combination of these two diseases can be considered poor. The differentialdiagnosis posed difficulties.
mesh_terms: D000293:Adolescent; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D003424:Crohn Disease / Q000150:complications / Q000235:genetics*; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007580:Jejunal Neoplasms / Q000150:complications / Q000235:genetics*; D010580:Peutz-Jeghers Syndrome / Q000150:complications / Q000235:genetics*
vernacular_title: Familiäres Vorkommen von Peutz-Jeghers-Syndrom und Morbus Crohn mit Manifestation beider Erkrankungen beim gleichen Patienten.