Tandem duplication of 10(q21-q22) in a mentally deficient man.
A mentally retarded man with congenital malformations, carrying a tandem duplication of 10(q21-q22) is reported. The clinical picture is compared with the description of previously reported cases and the possible origin of the aberrant chromosome is discussed.
D000328:Adult; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002906:Chromosomes, Human, 6-12 and X; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D007621:Karyotyping; D008214:Lymphocytes / Q000166:cytology; D008297:Male