Chloroquine-induced neuromyopathy. Report of a case.
A patient is described in whom a neuromyopathy developed during a long chloroquine treatment for systemic lupus erythematosus (SLE). The presence of a granular deposition within the muscle fibers was observed and led to discontinuation of the drug and to a gradual recovery of muscle strength. The difficult differential diagnosis with polymyositis, steroid-induced myopathy and SLE myositis is discussed.
D000328:Adult; D002738:Chloroquine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D009132:Muscles / Q000187:drug effects / Q000473:pathology; D009220:Myositis / Q000175:diagnosis; D009468:Neuromuscular Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology
D002738:Chloroquine