Synthesis and properties of a modified 2'-5'-adenylate trimer containing 2'-terminal 8-bromoadenosine.
The trimer of 2',5'-oligoadenylic acids bearing at the 2'-terminal 8-bromo or 8-hydroxyadenosines have been synthesiszed by the phosphotriester approach. Their properties are also described.
D000227:Adenine Nucleotides / Q000138:chemical synthesis*; D000241:Adenosine / Q000031:analogs & derivatives*; D002942:Circular Dichroism; D007202:Indicators and Reagents; D009690:Nucleic Acid Conformation; D009843:Oligoribonucleotides / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship
D000227:Adenine Nucleotides; D007202:Indicators and Reagents; D009843:Oligoribonucleotides; C036038:8-bromoadenosine; C023505:2',5'-oligoadenylate; D000241:Adenosine