[Use of anti-digoxin antibodies in digitalis poisoning in an infant].
Digitalis poisoning is rare, always iatrogenic and potentially lethal in infants. We report one case of severe poisoning in which treatment with digoxin Fab antibody fragments was successful. Evolution of plasma digitoxin levels showed an initial rapid decrease (T 1/2:1 hour), then a slower decline (T 1/2:5.5 days). No undesirable side-effects were observed.
D000906:Antibodies / Q000008:administration & dosage*; D004074:Digitoxin / Q000506:poisoning*; D004077:Digoxin / Q000276:immunology*; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000008:administration & dosage; D007231:Infant, Newborn
D000906:Antibodies; D007140:Immunoglobulin Fab Fragments; D004077:Digoxin; D004074:Digitoxin
Utilisation des anticorps anti-digoxine au cours d'une intoxication digitalique chez un nourrisson.