title: The cerebellum of epileptics.
abstract: Five cases are presented with different types of cerebellar lesions which may be encountered in epileptics. Case 1 represents typical postical lesions, Case 2 perinatal anoxic-ischemic damage, Case 3 transneuronal degeneration causing crossed cerebellar atrophy, Case 4 iatrogenic cerebellar atrophy due to Phenytoin toxicity. Case 5 illustrates the interaction of two mechanisms, postictal lobular sclerosis and transneuronal degeneration. It is suggested that by attention to the type and distribution of the cerebellar lesions, to the clinical history and to the distribution of lesions in other parts of the brain the pathogenetic mechanisms can be elucidated in most cases.
mesh_terms: D000293:Adolescent; D000328:Adult; D001284:Atrophy; D002526:Cerebellar Diseases / Q000139:chemically induced / Q000150:complications* / Q000473:pathology; D002531:Cerebellum / Q000473:pathology*; D004827:Epilepsy / Q000150:complications / Q000473:pathology*; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000151:congenital; D007223:Infant; D008297:Male; D008875:Middle Aged; D010672:Phenytoin / Q000009:adverse effects
chemical_list: D010672:Phenytoin