Two methods for flat-mounting cortical tissue.
Two procedures are described which allow cortical grey matter to be unfolded and flattened. Tangential sections of the flat-mounted tissue can reveal clear histological views of horizontal variations in cortical structure and function; these anatomical variations would be hard to see in sections cut by conventional techniques. Examples are presented from non-human primate tissue, but the technique has also been used successfully in a number of other mammalian species, including man. Advantages and disadvantages of the various methods for extracting topographical patterns from the cortex are discussed.
D000818:Animals; D001029:Aotus trivirgatus; D001345:Autoradiography / Q000379:methods; D002415:Cats; D002540:Cerebral Cortex / Q000166:cytology*; D003847:Deoxyglucose; D006651:Histocytochemistry / Q000379:methods*; D008251:Macaca; D008867:Microtomy / Q000379:methods*; D012453:Saimiri
D003847:Deoxyglucose