Solitary retinal astrocytoma.
The clinicopathologic features of retinal or optic disc astrocytomas are discussed based on eighteen reported cases. In addition, a new case of solitary retinal astrocytoma in a patient without other stigmata of phakomatosis is described. The tumor was prominently vascular and caused total exudative retinal detachment. It doubled in diameter over the seven months prior to enucleation, which was dictated by the occurrence of neovascular glaucoma. The astrocytic nature of the lesion was confirmed by immunohistochemical techniques (glial fibrillary acidic protein stain) and by electron microscopy.
D000293:Adolescent; D001253:Astrocytes / Q000648:ultrastructure; D001254:Astrocytoma / Q000473:pathology* / Q000601:surgery; D005134:Eye Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D005451:Fluorescein Angiography; D005901:Glaucoma / Q000473:pathology; D006801:Humans; D012160:Retina / Q000473:pathology; D012163:Retinal Detachment / Q000473:pathology; D012164:Retinal Diseases / Q000473:pathology* / Q000601:surgery