On the reactions of DL-1,3-dimethylthymine epoxide with amines and L-amino acid derivatives.
Reaction of DL-1,3-dimethylthymine epoxide (1) with aniline gave (2A) and (3A). Isomerization of (2A) provided (3A), (4) and (5). Reaction of (1) with L-amino acid ethyl ester afforded four optically active diastereomers.
D000588:Amines; D000596:Amino Acids; D055598:Chemical Phenomena; D002621:Chemistry; D007536:Isomerism; D013329:Structure-Activity Relationship; D013941:Thymine / Q000031:analogs & derivatives*
D000588:Amines; D000596:Amino Acids; C047919:1,3-dimethylthymine epoxide; D013941:Thymine