Blood lipid profile in healthy subjects treated with ticlopidine.
The study was carried out in order to evaluate if Ticlopidine induces lipid metabolism changes. Twenty seven healthy subjects were studied, 14 with placebo and 13 with Ticlopidine treatment (500 mg/day), for 30 days. Total cholesterol, HDL cholesterol, triglycerides, apolipoproteins A and B were evaluated before and after treatment. No significant changes of the blood lipid parameters were observed.
D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000494:pharmacology*; D001161:Arteriosclerosis / Q000188:drug therapy; D001792:Blood Platelets / Q000187:drug effects; D004311:Double-Blind Method; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013876:Thiophenes / Q000494:pharmacology*; D013988:Ticlopidine
D000925:Anticoagulants; D008055:Lipids; D013876:Thiophenes; D013988:Ticlopidine