Fatal intracranial hemorrhage associated with phenylpropanolamine, pentazocine, and tripelennamine overdose.
Hemorrhagic cerebrovascular accident is an uncommon but serious complication of drug overdose. A case of fatal intracranial hemorrhage following overdose with phenylpropanolamine, pentazocine, and tripelennamine is presented. The pharmacology, pathophysiology, clinical presentation, and management of poisoning by these agents are discussed.
D000328:Adult; D000662:Amphetamines / Q000652:urine; D002543:Cerebral Hemorrhage / Q000139:chemically induced*; D004357:Drug Synergism; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D013287:Illicit Drugs / Q000506:poisoning; D008297:Male; D010423:Pentazocine / Q000506:poisoning*; D010665:Phenylpropanolamine / Q000009:adverse effects*; D019966:Substance-Related Disorders / Q000150:complications*; D014309:Tripelennamine / Q000506:poisoning*
D000662:Amphetamines; D013287:Illicit Drugs; D010665:Phenylpropanolamine; D014309:Tripelennamine; D010423:Pentazocine