[Mutagenic action of different alcohols in an experiment].
Ethanol, ethylene glycol and glycerine induce chromosomal aberrations in cells of the rat bone marrow and disturb a genetic apparatus of male sex cells at the stage of late spermatids. The cytogenetic activity of ethylene glycol depends on its dose. Phenobarbital stimulates the cytogenetic activity of ethanol and ethylene glycol.
D000438:Alcohols / Q000633:toxicity*; D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000648:ultrastructure; D002869:Chromosome Aberrations; D004305:Dose-Response Relationship, Drug; D004622:Embryo, Mammalian / Q000187:drug effects / Q000648:ultrastructure; D047108:Embryonic Development / Q000187:drug effects; D000431:Ethanol / Q000633:toxicity; D019855:Ethylene Glycol; D005026:Ethylene Glycols / Q000633:toxicity; D005260:Female; D005990:Glycerol / Q000633:toxicity; D008297:Male; D009153:Mutagens / Q000633:toxicity*; D010634:Phenobarbital / Q000633:toxicity; D011247:Pregnancy; D051381:Rats; D013087:Spermatids / Q000187:drug effects / Q000648:ultrastructure
D000438:Alcohols; D005026:Ethylene Glycols; D009153:Mutagens; D000431:Ethanol; D019855:Ethylene Glycol; D005990:Glycerol; D010634:Phenobarbital
O mutagennom deĭstvii razlichnykh spirtov v éksperimente.