Cytogenetic effects in lymphocytes of formaldehyde workers of a paper factory.
Chromosome analyses were carried out in lymphocytes from 20 male papermakers exposed to formaldehyde (FA) for 2-30 years. 20 male workers from the same factory but without FA exposure served as controls. In the exposed group a significantly increased incidence of dicentrics or dicentrics and ring chromosomes was observed for 11 workers currently employed as supervisors. In contrast to 9 operators their total mean exposure time to FA was about 2.5 times longer. No significantly higher SCE values were found for smoking or for non-smoking FA workers compared with the corresponding control subjects.
D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D002869:Chromosome Aberrations; D005557:Formaldehyde / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010209:Paper; D012854:Sister Chromatid Exchange / Q000187:drug effects; D012907:Smoking; D013997:Time Factors
D000395:Air Pollutants, Occupational; D005557:Formaldehyde