title: [Comparative study of the vitamin activity of pyridoxal phosphate and pyridoxine used cutaneously].
abstract: In white rats with B6-avitaminosis, the B6-vitamin activity of pyridoxal-phosphate and of pyridoxine was studied in their epicutaneous and peroral application. It is revealed that pyridoxal-phosphate in epicutaneous application displays more activity than pyridoxine and pyridoxal-phosphate applied perorally. Pyridoxine in epicutaneous application does not reveal the B6-vitamin activity.
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004655:Emulsions; D011732:Pyridoxal Phosphate / Q000008:administration & dosage*; D011735:Pyridoxic Acid / Q000652:urine; D011736:Pyridoxine / Q000008:administration & dosage*; D051381:Rats; D013997:Time Factors; D026681:Vitamin B 6 Deficiency / Q000188:drug therapy / Q000652:urine
chemical_list: D004655:Emulsions; D011735:Pyridoxic Acid; D011732:Pyridoxal Phosphate; D011736:Pyridoxine
vernacular_title: Sravnitel'noe izuchenie vitaminnoĭ aktivnosti piridoksal'-fosfata i piridoksina pri ikh nakozhnom primenenii.