Offspring of alcoholics have enhanced antagonistic placebo response.
In this study, 85 college-age men who reported normal drinking practices believed they were drinking malt liquor when they actually drank dealcoholized beer. Following drinking, 11 subjects with an alcoholic biological father showed a significantly larger heart rate decrease (p less than .05) than subjects with a nonalcoholic father. The results are discussed in terms of opponent process and classical conditioning theories of addiction, and the etiological pathway from risk factor to final manifestation of alcoholism.
D000328:Adult; D000428:Alcohol Drinking; D000435:Alcoholic Intoxication / Q000523:psychology; D000437:Alcoholism / Q000235:genetics* / Q000523:psychology; D000704:Analysis of Variance; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D010919:Placebos; D012306:Risk; D012647:Self-Assessment; D012951:Socialization
D010919:Placebos