Fascial elastosis mimicking eosinophilic fasciitis.
A 75-year-old woman rapidly developed symmetric skin induration with overlying venous furrowing of the inner arms and lateral thighs. This clinical picture and routine histopathologic study with fascial thickening and inflammation suggested a diagnosis of eosinophilic fasciitis. However, elastic tissue stain revealed marked accumulation of irregularly contoured elastin fibers which accounted for the majority of the fascial thickening. This previously undescribed condition is termed fascial elastosis.
D000368:Aged; D001132:Arm; D003937:Diagnosis, Differential; D004547:Elastic Tissue / Q000473:pathology*; D004802:Eosinophilia / Q000175:diagnosis*; D005205:Fascia / Q000473:pathology*; D005208:Fasciitis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D013848:Thigh