Massive congenital mesenchymal malformation of the lung: a case report with ultrastructural study.
An unusual congenital tumorous malformation of mesenchymal tissue caused severe respiratory distress in a premature infant. The solid mass, which replaced almost the entire left lung, was composed of interlacing fascicles of spindle cells that percolated through otherwise well-developed fetal lung tissue. The normal anatomic arrangement of bronchial components was altered, but bronchial cartilages were present. Ultrastructural study of the lesion showed mesenchymal cells with fibroblastic differentation.
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000473:pathology; D008168:Lung / Q000002:abnormalities* / Q000473:pathology / Q000648:ultrastructure; D008854:Microscopy, Electron