title: [Toxicological evaluation of the outgassing of tetrafluoroethylene-based thermostable polymeric materials during heating].
abstract: The purpose of this study was to investigate the composition and toxicity of fluoroplastic F-40 thermodestruction products at 300-500 degrees C and to identify the maximally allowable temperature for their safe use. When heated over 400 degrees C, the products of luoroplastic F-40 evolution included such compounds as hydrogen fluoride, fluro-organic compounds, carbon monoxide, formaldehyde. When heated at 500 degrees C, the thermodestruction products caused the highest mortality rate of mice. The pathogenesis and clinical development of fluoroplastic F-40 poisoning are primarily associated with fluoro-compounds. It is concluded that the temperature 300 degrees C is the maximum temperature at which tetrafluroethylene-based polymers can be used.
mesh_terms: D000818:Animals; D003252:Construction Materials / Q000009:adverse effects / Q000032:analysis*; D004781:Environmental Exposure; D006358:Hot Temperature; D051379:Mice; D011138:Polytetrafluoroethylene / Q000032:analysis* / Q000633:toxicity; D051381:Rats; D013026:Space Flight; D013696:Temperature; D014835:Volatilization
chemical_list: D011138:Polytetrafluoroethylene
vernacular_title: Toksikologicheskaia otsenka gazovydeleniia termostoĭkikh polmernykh materialov na osnove tetraftorétilena pri ikh nagrevanii.