title: Perinatal piglets under sublethal concentrations of atmospheric carbon monoxide.
abstract: Perinatal exposure to atmospheric carbon monoxide at sublethal concentrations affected neonatal piglets negatively. Low total hemoglobin concentration and oxyhemoglobin saturation ratio were present at birth in piglets farrowed by gilts that had been exposed to carbon monoxide at 250 ppm from gestation d 109 on, but stillbirth rate was only 4.8%. Carboxyhemoglobin saturation ratio increased from .0 to 19.8 and 22.4% as carbon monoxide concentration rose from background (less than 5 ppm) to 200 and 250 ppm. Carbon monoxide affected neonatal piglets' behavior. Piglets exposed to atmospheric carbon monoxide at 250 ppm perinatally took longer to nurse for the first time than did counterparts under background or 200-ppm concentrations. Those under carbon monoxide at 250 ppm had compromised performance in behavior tests that measured a piglet's ability to orient itself in, maneuver in and investigate its environment, respectively.
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000097:blood / Q000502:physiology; D001522:Behavior, Animal; D002249:Carbon Monoxide Poisoning / Q000097:blood / Q000503:physiopathology / Q000662:veterinary*; D002263:Carboxyhemoglobin / Q000032:analysis; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D010108:Oxyhemoglobins / Q000032:analysis; D013552:Swine / Q000097:blood / Q000502:physiology*; D013553:Swine Diseases / Q000097:blood / Q000503:physiopathology*
chemical_list: D006454:Hemoglobins; D010108:Oxyhemoglobins; D002263:Carboxyhemoglobin