Observations on the action of strains of Yersinia enterocolitica from various sources on Hep-2 cells and human foetal gut.
Forty-five strains of Y enterocolitica including eleven from ankylosing spondylitis patients were examined for their ability to invade Hep-2 cells in culture. Nineteen out of twenty pathogenic strains were invasive and the rest were non-invasive. Three pathogenic strains were invasive, and three non-pathogenic strains were not invasive to human foetal gut. Invasiveness was not found to be useful for differentiating ankylosing spondylitis from non-ankylosing spondylitis strains.
D000268:Adhesiveness; D000818:Animals; D002460:Cell Line; D002462:Cell Membrane / Q000382:microbiology; D002682:Chinchilla; D004285:Dogs; D006801:Humans; D007082:Ileum / Q000196:embryology / Q000382:microbiology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D013167:Spondylitis, Ankylosing / Q000382:microbiology*; D015009:Yersinia Infections / Q000382:microbiology*; D015008:Yersinia enterocolitica / Q000472:pathogenicity*