Characterization of P4, a natural inhibitor of cellular cytotoxicity reaction in pregnant women.
A factor present in the serum of pregnant women is able to inhibit nonspecifically a cellular cytotoxicity reaction. This glycoprotein called P4, is an alpha-globulin whose molecular weight is 200,000 daltons bound to albumin. Its isoelectric point is 4.1. By its various characteristics, P4 seems different from other proteins so far described.
D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000097:blood*; D008970:Molecular Weight; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000302:isolation & purification*
D007166:Immunosuppressive Agents; D011257:Pregnancy Proteins; C048000:pregnancy protection protein P4