Separation and identification of non-steroidal antirheumatic drugs containing a free carboxyl function using high-performance liquid chromatography.
Different methods for the separation and identification of eighteen non-steroidal antirheumatics (non-steroidal, anti-inflammatory drugs) and the application of these methods for systematic toxicological analysis are reviewed. A method for separating these compounds by high-performance liquid chromatography using an RP-18 column and mixtures of acetonitrile and acetate buffers as eluents is presented and the detectability of these substances with respect to their different UV maxima is discussed.
D000893:Anti-Inflammatory Agents / Q000652:urine*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D013056:Spectrophotometry, Ultraviolet
D000893:Anti-Inflammatory Agents