Absorption of magnesium and other macrominerals in sheep infused with potassium in different parts of the digestive tract.
Two metabolism trials were conducted with 12 crossbred wether lambs, each surgically equipped with a ruminal catheter and abomasal and ileal cannulae, to study the effect of K infusion in different sites of the digestive tract on site of absorption and flow of minerals. The treatments consisted of the infusion of 33.6, 12.0 or 12.0 g K/d as bicarbonate into either the rumen, abomasum or ileum, respectively. Each trial consisted of a minimum 5-d preliminary period, five 3-d collection periods to determine mineral balance and a 6-d sampling period to determine mineral flow and site of absorption. Chromic oxide was incorporated into the diet for use as a marker. Magnesium was absorbed primarily from the preintestinal region. Ruminal infusion of K tended to decrease preintestinal Mg absorption. Absorption of Mg in the entire tract was decreased (P less than .05) 43% when K was infused into the rumen. There was a slight absorption of Mg in the small intestine, followed by a net secretion into the large intestine. Serum Mg levels tended to be depressed in lambs infused with K intraruminally. Calcium flow from the preintestinal region was decreased (P less than .05) by infusion of K into the rumen. Only lambs infused with K in the rumen had a net secretion of Na into the small intestine. The large intestine was the primary site of net Na absorption for ruminal-infused lambs. Phosphorus flow from the preintestinal region was decreased (P less than .05) by infusion of K into the rumen. Potassium flow from both the preintestine and small intestine was increased (P less than .05) by ruminal K infusion. The infusion of K into the rumen, abomasum or ileum increased (P less than .05) the total absorption of K, with the small intestine being the major absorptive site. The infusion of potassium bicarbonate into the rumen of sheep raised (P less than .05) the pH of the ruminal contents 15%. Ruminal infusion of K depresses Mg absorption, while the infusion of K into the abomasum or ileum does not affect Mg absorption. Therefore, the role of K in grass tetany may be via this depression of Mg absorption.
D000018:Abomasum / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000097:blood / Q000378:metabolism; D007082:Ileum / Q000378:metabolism; D007408:Intestinal Absorption; D008274:Magnesium / Q000097:blood / Q000378:metabolism*; D008297:Male; D010758:Phosphorus / Q000097:blood / Q000378:metabolism; D011188:Potassium / Q000097:blood / Q000378:metabolism / Q000494:pharmacology*; D012417:Rumen / Q000378:metabolism; D012756:Sheep / Q000378:metabolism*; D012964:Sodium / Q000097:blood / Q000378:metabolism
D010758:Phosphorus; D012964:Sodium; D008274:Magnesium; D011188:Potassium; D002118:Calcium