[Cisplatin or combined cisplatin and 60Co radiation in the treatment of advanced lung cancer--report of 145 cases].
The result of 145 patients with advanced primary lung cancer treated by cisplatin alone or combined cisplatin and 60Co radiation from June 1981 to August 1983 is reported. 75 of these cases were clinical stage III and 70 stage IV. 57 (39%) were proved by pathology and 64 (44%) by cytology, totalling 121 (83%) as non-small cell lung cancers. The other 24 (17%) were diagnosed by clinical means. All the patients were divided into two groups. Group I, 26 cases were treated by cisplatin alone. In this group, no complete response was found, the partial response rate was 31% and 1-year survival rate was 40%. Group II, 119 patients were treated by the combination of cisplatin and 60Co radiation. Complete response rate was 16%, partial 59%, 1 and 2-year survival rates were 52% and 33%, respectively. The results show that the combination of cisplatin and 60Co therapy is more effective for the advanced lung cancers.
D000230:Adenocarcinoma / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy; D002945:Cisplatin / Q000627:therapeutic use*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D008875:Middle Aged
D003037:Cobalt Radioisotopes; D002945:Cisplatin