[Effect of new quaternary imino compounds against selected bacterial and fungal strains. 11. Synthesis of 1-methyl- and 1-ethyl-3-(n-alkoxymethyl)imidazolium chlorides].
Syntheses and antibacterial activity of the imidazolium compounds are described. Syntheses of the imidazolium chlorides were performed by reaction of 1-alkylimidazole with chloromethylalkyl ether. Antibacterial properties of obtained compounds was tested on 13 strains of bacteria and fungi. Chlorides with n-dodecaoxymethyl radical indicated the best antibacterial activity.
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D007093:Imidazoles; C018100:1-methylimidazole
Wirkung neuer quartärer Iminiumverbindungen gegen ausgewählte Bakterien- und Pilzstämme. Teil 11: Synthese von 1-Methyl- und 1-Ethyl-3-(n-alkoxymethyl)imidazoliumchloriden.