Inhibitory effect of nocardia rubra cell wall skeleton on splenomegaly induced by Friend leukemia virus in mice.
Antitumorigenic effect of Nocardia rubra cell wall skeleton (N-CWS) was evaluated by its ability to prevent splenomegaly induced by Friend leukemia virus (FLV) in C3H/HeN mice. Pretreatment with N-CWS significantly inhibited the splenomegaly as evidenced by the lack of increase in spleen weight but N-CWS given after FLV inoculation had no effect.
D000818:Animals; D002473:Cell Wall / Q000502:physiology; D005622:Friend murine leukemia virus; D007942:Leukemia, Experimental / Q000150:complications* / Q000628:therapy; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D009615:Nocardia / Q000502:physiology*; D013163:Splenomegaly / Q000209:etiology / Q000517:prevention & control*