[Control of cell multiplication in vitro. V. The dependence of cell multiplication on the ganglioside content].
The concentration and composition of gangliosides in the cells of L-line and its clones--L-2 and Lebr 1/1, with values of saturation densities being 0.9, 1.6 and 3.2 X 10(5) cells/mc2, respectively, were compared. The transition of populations in the stationary growth phase was shown to be accompanied by an increment of ganglioside concentration and accumulation of di- and three-sialogangliosides. The data obtained are discussed in connection with the previously published results about changing intracellular cAMP content and conA-mediated agglutination at density-dependent growth inhibition L-cell variants.
D000818:Animals; D002452:Cell Count; D002455:Cell Division; D005732:Gangliosides / Q000378:metabolism*; D007739:L Cells / Q000166:cytology* / Q000378:metabolism; D051379:Mice
D005732:Gangliosides
Kontrol' razmnozheniia kletok in vitro. V. Zavisimost' razmnozheniia kletok ot soderzhaniia v nikh gangliozidov.