[Brain enzyme activity in irradiated sympathectomized rats].
The results are reviewed from studies of activity of hexokinase (2.7.1.1.EC), dehydrogenase glucose-6-phosphate (1.1.1.49 EC), and cholinesterase (3.1.1.7 EC) in subcellular fractions of rat brain at the background of chemical sympathectomy induced by long-term administration of guanethidine and subsequent irradiation with a dose of 7 Gy. In conditions of sympathectomy, the enzyme activity is inhibited; in irradiated sympathectomized rats, activity of hexokinase and cholinesterase increases to reach the level of that of intact animals while dehydrogenase remains inhibited.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D002802:Cholinesterases / Q000378:metabolism; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006145:Guanethidine; D006593:Hexokinase / Q000378:metabolism; D008297:Male; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D013563:Sympathectomy, Chemical; D013564:Sympathetic Nervous System / Q000502:physiology*
D005954:Glucosephosphate Dehydrogenase; D006593:Hexokinase; D002802:Cholinesterases; D006145:Guanethidine
Aktivnost' nekotorykh fermentov mozga pri obluchenii desimpatizirovannykh krys.