title: [Primary hemostatic disorders caused by beta-lactams. Apropos of a postoperative hemorrhagic complication during treatment with cephalexin].
abstract: The authors report a case of haemorrhage due to cephalexin therapy. The bleeding started after an orthopedic operation in a patient without renal failure, receiving 3 g/day of cephalexin. Platelet function was very abnormal at the time of the haemorrhage with a bleeding time of over 20 minutes, which returned to normal when treatment was stopped. This case seems to be similar to other reports of haemorrhages during treatment with other beta-lactams.
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001778:Blood Coagulation Disorders / Q000139:chemically induced*; D002506:Cephalexin / Q000009:adverse effects*; D005260:Female; D006406:Hematoma / Q000139:chemically induced*; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D011183:Postoperative Complications
chemical_list: D000900:Anti-Bacterial Agents; D002506:Cephalexin
vernacular_title: Les troubles de l'hémostase primaire dus aux bêta-lactamines. A propos d'un accident hémorragique post-opératoire au cours d'un traitement par la céfalexine.