Lymphocyte subpopulations and cell mediated cytotoxicity in acute non-lymphoid leukemia (ANLL) patients in complete remission (CR) and off-therapy.
An assessment of the lymphocyte sub-populations and cell mediated cytotoxicity was made in 12 adults with acute non-lymphoid leukemia after stopping chemotherapy. No significant differences were found between ANLL and controls, for absolute lymphocyte count, %SIg/+ cells, Fc gamma + cells and ERFC. The OKT4+/OKT8+ was reduced in ANLL. Leu-7+ cells were significantly higher in ANLL. Moreover it appears that in ANLL lymphocyte function is restored early after stopping chemotherapy.
D000208:Acute Disease; D000328:Adult; D000920:Antibody-Dependent Cell Cytotoxicity; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007938:Leukemia / Q000276:immunology*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000276:immunology*; D008875:Middle Aged