title: [Electron microscopic and radioautographic study of the wall of the large bronchi in chronic inflammatory processes in the lungs].
abstract: Synthesis of DNA, RNA and protein in the structures of large bronchi in patients with chronic inflammatory processes was studied. It was shown, that nuclei of all cell types of the tegmental bronchial epithelium, capillary endotheliocytes and stromal cells actively included 3H-uridine. By the intensification of bronchial wall sclerosis index and hardness of label with 3H-uridine were reduced in epitheliocytes, endotheliocytes, pericytes, labrocytes, macrophages, but were increased in fibroblasts which also had a high level of 3H-proline inclusion. High index of label with 3H-thymidine was found in basal cells of epithelium and capillary endotheliocytes. In conditions of chronic inflammation of bronchial wall the greatest metabolic and proliferative activity was found in the capillary endotheliocytes and cells of a pericapillary zone. In sclerosis the proliferative activity of basal cells was changed, that predetermined the character of tegmental epithelium reorganization.
mesh_terms: D001345:Autoradiography; D001706:Biopsy; D001980:Bronchi / Q000378:metabolism / Q000648:ultrastructure*; D001991:Bronchitis / Q000378:metabolism / Q000473:pathology*; D002908:Chronic Disease; D004848:Epithelium / Q000378:metabolism / Q000648:ultrastructure; D006651:Histocytochemistry; D006801:Humans; D008854:Microscopy, Electron; D012598:Sclerosis; D014316:Tritium
chemical_list: D014316:Tritium
vernacular_title: Elektronno-radioavtograficheskoe issledovanie stenki krupnykh bronkhov pri khronicheskikh vospalitel'nykh protsessakh v legkikh.