[Mechanisms of natural resistance. The ambivalent developmental role of leukocytes infiltrating neoplastic tissues].
Neoplastic tissues are often infiltrated by normal leukocytes. Morphological, histochemical and monoclonal antibody-defined markers are now available by which these cells can be separated in vitro or identified in situ. The analysis of the origin, regulation and function of cells of the lymphoreticular infiltrate of tumors reveals that they can be ambivalent in the regulation of neoplastic growth.
D000818:Animals; D000911:Antibodies, Monoclonal; D002471:Cell Transformation, Neoplastic; D002630:Chemotactic Factors / Q000032:analysis; D006801:Humans; D007694:Killer Cells, Natural / Q000502:physiology; D007962:Leukocytes / Q000502:physiology*; D051379:Mice; D009000:Monocytes / Q000502:physiology; D010586:Phagocytes / Q000502:physiology; D010982:Platelet-Derived Growth Factor / Q000032:analysis
D000911:Antibodies, Monoclonal; D002630:Chemotactic Factors; D010982:Platelet-Derived Growth Factor
Meccanismi di resistenza naturale. Il ruolo ambiguo svolto dai leucociti infiltranti i tessuti neoplastici.