Opitz-Frias syndrome. A case with potentially hazardous anaesthetic implications.
The anaesthetic management is described of a nine-month-old male for surgical palliation of the the functional abnormalities associated with Opitz-Frias syndrome. Features of this syndrome of interest to anaesthetists include recurrent pulmonary aspiration of intestinal contents, achalasia of the oesophagus, subglottic stenosis, hypertelorism, micrognathia and a high arched palate. No previous reports of anaesthesia for patients with this condition have been identified.
D000015:Abnormalities, Multiple / Q000601:surgery*; D000768:Anesthesia, General / Q000379:methods*; D004931:Esophageal Achalasia / Q000601:surgery; D005837:Genitalia, Male / Q000002:abnormalities; D006323:Heart Arrest / Q000150:complications*; D006801:Humans; D006972:Hypertelorism / Q000601:surgery; D007223:Infant; D008297:Male; D009056:Mouth Abnormalities / Q000601:surgery; D011015:Pneumonia, Aspiration / Q000150:complications*; D013577:Syndrome