[Distribution of haptoglobin phenotypes in gynecologic tumors].
The haptoglobin types were determined by starch gel electrophoresis in 246 women with benigne and malignant gynaecologic neoplasms or breast tumors. There was a higher Hp1-gene frequency in all investigated patients compared with the normal distribution caused by a significant increase of Hp 1-1 type and a lower rate of Hp 2-2 type. The Hp 2-2 type was lower in the cases with benigne and malignant neoplasms of cervix and cervical carcinomas. The Hp 1-1 type was higher in the group of mamma tumors. A connection between these findings and the immune systems is discussed.
D001943:Breast Neoplasms / Q000235:genetics; D004592:Electrophoresis, Starch Gel; D005260:Female; D005787:Gene Frequency; D005833:Genital Neoplasms, Female / Q000235:genetics*; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D010051:Ovarian Neoplasms / Q000235:genetics; D010641:Phenotype; D002583:Uterine Cervical Neoplasms / Q000235:genetics; D014594:Uterine Neoplasms / Q000235:genetics
D006242:Haptoglobins
Zur Verteilung der Haptoglobinphänotypen bei gynäkologischen Tumoren.