[Frequent occurrence of Yersinia infection in hemosiderosis].
Antibodies against Yersinia were found in 12 of 50 patients with hemosiderosis, in 11 of 47 patients with thalassemia major and in one of three patients with Blackfan-Diamond anemia. All patients were treated with subcutaneous continuous deferoxamin-infusions. A systemic yersiniosis occurred in seven patients, all with homozygous beta-thalassemia, in five during and in two before treatment with deferoxamin. Hemosiderosis and infusions with deferoxamin seem to increase the risk of yersinia septicemia.
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D005293:Ferritins / Q000097:blood; D006486:Hemosiderosis / Q000276:immunology*; D006801:Humans; D007501:Iron / Q000097:blood; D013156:Splenectomy; D013789:Thalassemia / Q000276:immunology; D015009:Yersinia Infections / Q000276:immunology*; D015008:Yersinia enterocolitica / Q000276:immunology
D000907:Antibodies, Bacterial; D005293:Ferritins; D007501:Iron
Gehäuftes Auftreten von Yersiniensepsis bei Hämosiderose.