Catacandins, novel anticandidal antibiotics of bacterial origin.
Two novel antibiotics, catacandin A and catacandin B, were isolated from the fermentation broth of the bacterium, Lysobacter gummosus, by extraction and adsorption, reverse-phase and gel filtration chromatography. On the basis of their physico-chemical properties, they are acyltetramic acids that are easily distinguishable from others in this class. Catacandin A and catacandin B possess good anticandidal activity.
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000378:metabolism*; D002175:Candida / Q000187:drug effects*; D055598:Chemical Phenomena
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents