[Clinical evaluation on combination therapy of antibiotics and a gamma-globulin preparation (SM-4300) in the field of pediatrics].
Ten cases of bacterial infections, showing no or insufficient response to antibacterial chemotherapy, were treated with a new intravenous human gamma-globulin (SM-4300). SM-4300 was administered intravenously (68-172 mg/kg/day) once a day for 1-3 days. SM-4300 was effective in 6 out of 8 pneumonia cases and also in 1 out of 2 septicemia cases. In none of the 10 cases, any side effects were observed.
D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001419:Bacteria / Q000276:immunology; D001424:Bacterial Infections / Q000628:therapy*; D001996:Bronchopneumonia / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007136:Immunoglobulins / Q000008:administration & dosage*; D007223:Infant; D008297:Male; D011014:Pneumonia / Q000628:therapy
D000900:Anti-Bacterial Agents; D007136:Immunoglobulins; C044640:SM-4300