[Clinical study on pulmonary metastases of differentiated thyroid carcinoma--with special reference to the extent of thyroid resection and RI therapy].
Prognosis of differentiated thyroid carcinoma is favorable unless distant metastasis develops. We have experienced 70 cases of differentiated thyroid carcinoma with pulmonary metastases and analysed the outcome of treatment of patients, with special reference to the extent of thyroid resection and postoperative ablative RI therapy. The following results were obtained: Of the 42 survivors 22 (52.4%) received total thyroidectomy, whereas 23 of 28 expired patients underwent less-than-total thyroidectomy. A total of 42 patients underwent radioiodine treatment following thyroid resection. 17 out of 18 patients who had received total thyroidectomy survived. On the other hand, only 11 out of 24 patients who had received less-than-total thyroidectomy survived. In the non-RI treatment group, prognoses were unfavorable in both total and less-than-total thyroidectomy groups. From these results, it is emphasized that ablative doses of RI should be given to patients with pulmonary metastases of differentiated thyroid carcinoma after total thyroidectomy.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002291:Carcinoma, Papillary / Q000556:secondary; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*; D008175:Lung Neoplasms / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013964:Thyroid Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods
D007457:Iodine Radioisotopes