title: The effects of double J stenting on unobstructed ureters. An experimental and clinical study.
abstract: Upper tract pressure flow studies in four clinically unobstructed ureters with double J stents in situ indicated that urinary flow occurred mainly around the stent and that there was significant vesicorenal pressure transmission. This study examined the dynamics of ureteric urinary flow and morphological effects consequent upon stenting a ureter in vivo. In a porcine model, ureteric intubation caused a rise in intrapelvic pressures, hydroureter, vesicorenal reflux and generalised thickening of the ureteric wall with characteristic histological changes in the urothelium. These findings suggest that double J stents may compromise urinary drainage when ureteric obstruction is not present, urging caution in their use in the damaged, unobstructed upper urinary tract.
mesh_terms: D000818:Animals; D002408:Catheters, Indwelling; D006801:Humans; D008954:Models, Biological; D011140:Polyurethanes; D011312:Pressure; D012828:Silicones; D013552:Swine; D014513:Ureter / Q000503:physiopathology*; D014546:Urinary Catheterization; D014547:Urinary Diversion / Q000379:methods*; D014563:Urodynamics
chemical_list: D011140:Polyurethanes; D012828:Silicones