title: Exploration and habituation in nervous mutant mice.
abstract: Nervous mutant mice have selective damage to deep cerebellar nuclei and Purkinje cells. Compared to normal littermate controls, nervous mutant mice did not show habituation of a hole poke response to a large hole. The nervous mutants showed both signs of increased contact with a novel stimulus (number of rearing responses) and decreased exploration (number of hole pokes in small holes). Results are discussed in terms of a similarity between the behavioral effects of cerebellar damage and hippocampal damage.
mesh_terms: D000818:Animals; D001259:Ataxia / Q000503:physiopathology; D002531:Cerebellum / Q000503:physiopathology; D005106:Exploratory Behavior / Q000502:physiology*; D005260:Female; D006185:Habituation, Psychophysiologic / Q000502:physiology*; D008297:Male; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000502:physiology*; D012160:Retina / Q000503:physiopathology