Effect of alcohol-feeding on gastric mucosal mast cell population and gastric tissue histamine concentration in albino rats.
Albino rats fed on 30% ethyl alcohol for 60 days demonstrated significant reduction in the histamine concentration of the gastric wall, estimated by bio-assay, as well as in the gastric mucosal mast cell population. It can, therefore be concluded that alcohol liberates histamine from the gastric mast cells even in the presence of alcohol-induced gastritis.
D000818:Animals; D000431:Ethanol / Q000494:pharmacology*; D005753:Gastric Mucosa / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D006632:Histamine / Q000378:metabolism*; D008297:Male; D008407:Mast Cells / Q000187:drug effects*; D051381:Rats
D000431:Ethanol; D006632:Histamine