d-Tubocurarine sensitivities of a fast and a slow neuromuscular system of the rat.
Fast and slow neuromuscular systems in the rat were compared with respect to their sensitivity to d-tubocurarine (dTC). The fast tibialis anterior was more sensitive than the slow soleus to dTC-induced block of contractile tension when stimulated at either 0.2 or 1.0 Hz. These results in the rat contrast those made by others in the cat. Thus, relative drug sensitivities are not simply related to neuromuscular type.
D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology; D009469:Neuromuscular Junction / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014403:Tubocurarine / Q000494:pharmacology*
D009466:Neuromuscular Blocking Agents; D014403:Tubocurarine