Fibronectin enhances transfection of Staphylococcus aureus.
The factor in normal sera primarily responsible for the enhancement of transfection (and transformation) of Staphylococcus aureus was identified as fibronectin. Serum samples which were depleted of fibronectin by affinity chromatography showed a marked decrease in enhancing activity. Fibronectin isolated from sera of several animal species demonstrated enhancing activity.
D000818:Animals; D001769:Blood; D003470:Culture Media; D005353:Fibronectins / Q000494:pharmacology*; D006736:Horses; D006801:Humans; D011817:Rabbits; D013045:Species Specificity; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics*; D014162:Transfection / Q000187:drug effects*
D003470:Culture Media; D005353:Fibronectins