Synthesis and antibacterial activity of some derivatives of the antibiotic thermorubin.
A series of derivatives has been prepared from the antibiotic thermorubin, some of which show a substantial modification of the original structure. The antibacterial activities are reported.
D000818:Animals; D000880:Anthraquinones / Q000138:chemical synthesis / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D051379:Mice; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; C005821:thermorubin