title: [Cholesterol esterase activity of human monocytes in ischemic heart disease].
abstract: The comparison on the effect of atherosclerotic lesion of the vascular system on changes in the activity of human blood mononuclear cell lysosomal and cytoplasmic cholesterolesterases showed that these changes were of diverse nature an increase in lysosomal cholesterolesterase activity and a decrease in cytoplasmatic activity. It can be accounted for be a different role of acid and alkaline cholesteroesterases in cell cholesterol metabolism and by different mechanisms of the regulation of these enzymes.
mesh_terms: D000328:Adult; D000368:Aged; D002265:Carboxylic Ester Hydrolases / Q000097:blood*; D003327:Coronary Disease / Q000201:enzymology*; D003593:Cytoplasm / Q000201:enzymology; D004789:Enzyme Activation; D005260:Female; D006801:Humans; D008247:Lysosomes / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000201:enzymology*; D002787:Sterol Esterase / Q000097:blood* / Q000172:deficiency
chemical_list: D002265:Carboxylic Ester Hydrolases; C031695:acid cholesterol ester synthetase; D002787:Sterol Esterase
vernacular_title: Izuchenie aktivnosti kholesterolesteraz monotsitov krovi cheloveka pri ishemicheskoĭ bolezni serdtsa.