[Limiting stress activation of the adrenergic and pituitary-adrenal systems by alpha-tocopherol].
alpha-Tocopherol reduced distinctly the intensity and duration of the stress reaction. Preadministration of alpha-tocopherol into animals before stress prevented the corticosterone elevation as well as the catecholamine decrease in heart muscle and adrenal glands; at the same time, the vitamin reduced 2-fold the duration of eosinopenia. Besides, the intensity of NA-3N neuronal uptake was twice increased in these tissues.
D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D002395:Catecholamines / Q000097:blood / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D010913:Pituitary-Adrenal System / Q000187:drug effects*; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects* / Q000378:metabolism; D013315:Stress, Psychological / Q000503:physiopathology* / Q000517:prevention & control; D014810:Vitamin E / Q000494:pharmacology*
D002395:Catecholamines; D011941:Receptors, Adrenergic; D014810:Vitamin E; D009638:Norepinephrine
Ogranichenie stressornoĭ aktivatsii adrenergicheskoĭ i gipofizarno-adrenalovoĭ sistem s pomoshch'iu alpha-tokoferola.