Ion-pair high-performance liquid chromatographic analysis of aspartame and related products.
A simple and accurate quantitative determination of aspartame (L-alpha-aspartyl-L-phenylalanine methyl ester), a new artificial sweetener, is described. The method, which is based on ion-pair high-performance liquid chromatography, allows the determination of aspartame in finished bulk and dosage forms, and the detection of a few related products at levels down to 0.1%.
D001218:Aspartame / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D003460:Crystallization; D004151:Dipeptides / Q000032:analysis*; D013549:Sweetening Agents / Q000032:analysis
D004151:Dipeptides; D013549:Sweetening Agents; D001218:Aspartame