[Synthesis, anthelmintic activity and acute toxicity of an isoquinoline pyrazine derivative (2-acyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino [2,1-a]isoquinolin-4-ones].
D000818:Animals; D000871:Anthelmintics / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D006224:Cricetinae; D004353:Drug Evaluation, Preclinical; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000627:therapeutic use; D008647:Mesocricetus; D051379:Mice; D009889:Opisthorchiasis / Q000188:drug therapy; D009891:Opisthorchis; D011719:Pyrazines / Q000138:chemical synthesis* / Q000627:therapeutic use; D013329:Structure-Activity Relationship
D000871:Anthelmintics; D007546:Isoquinolines; D011719:Pyrazines
Sintez, antgel'mintnaia aktivnost' i ostraia toksichnost' proizvodnogo izokhinolinpirazina (2-atsil-1,2,3,6,7,11b-gekagidro-4H-pirazino [2,1-a]izokhinolin-4-onov).