Nucleus basalis Meynert neurons contain the vitamin D-induced calcium-binding protein (Calbindin-D 28k).
The neurons of the monkey basal nucleus of Meynert are shown to contain a protein indistinguishable from the chicken intestinal 28kd vitamin D-dependent calcium-binding protein (Calbindin-D 28k; CPB). CBP is thought to shuttle and buffer Ca++-ions, thus regulating the intracellular calcium distribution and concentration. Our observation may engender interest in searching for the role Vitamin D-metabolites, the CBP and calcium-ions in the physiology and pathology of nucleus basalis Meynert neurons.
D000818:Animals; D001479:Basal Ganglia / Q000378:metabolism*; D002135:Calcium-Binding Proteins / Q000378:metabolism*; D003712:Dendrites / Q000378:metabolism; D005260:Female; D006651:Histocytochemistry; D007120:Immunochemistry; D008253:Macaca mulatta; D008297:Male; D009474:Neurons / Q000378:metabolism / Q000648:ultrastructure; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*; D012453:Saimiri; D013377:Substantia Innominata / Q000166:cytology / Q000378:metabolism* / Q000648:ultrastructure; D014018:Tissue Distribution
D002135:Calcium-Binding Proteins; D064030:S100 Calcium Binding Protein G