[AA amylosis and the nephrotic syndrome complicating a pulmonary epidermoid carcinoma].
A 59 year-old male developed the nephrotic syndrome in the course of squamous-cell lung carcinoma with metastases. Renal biopsy disclosed amyloid deposits. Immunofluorescence was positive with an anti-SAA antiserum. Amyloidosis complicates exceptionally lung tumors, despite extremely high serum levels of SAA in this type of malignancy. This infrequency shows that determinants other than high SAA serum levels are necessary to create tissue amyloid deposits.
D000310:Adrenal Gland Neoplasms / Q000556:secondary; D000686:Amyloidosis / Q000209:etiology* / Q000378:metabolism; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000378:metabolism; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D007678:Kidney Glomerulus / Q000378:metabolism; D007680:Kidney Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000150:complications* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000209:etiology*; D000685:Serum Amyloid A Protein / Q000032:analysis
D000685:Serum Amyloid A Protein
Amylose AA et syndrome néphrotique compliquant un carcinome épidermoïde pulmonaire.