title: [Cellular aspects of chondrodysplasia].
abstract: Studies of growing cartilage in cases of chondrodysplasia have demonstrated chondrocytic abnormalities, in particular the presence of abnormal inclusions. The histochemical and microchemical analysis of these inclusions provide valuable information concerning the pathophysiology of these diseases, which involves a variety of mechanisms: disorders of the metabolism of proteoglycans and glycosaminoglycans, collagen, lipids, glycoproteins, disorders of cell division.
mesh_terms: D002455:Cell Division; D003094:Collagen / Q000378:metabolism; D006023:Glycoproteins / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006132:Growth Plate / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D050356:Lipid Metabolism; D010009:Osteochondrodysplasias / Q000378:metabolism / Q000473:pathology*; D011509:Proteoglycans / Q000378:metabolism
chemical_list: D006023:Glycoproteins; D006025:Glycosaminoglycans; D011509:Proteoglycans; D003094:Collagen
vernacular_title: Aspects cellulaires des chondrodysplasies.