Study of local anesthetics. Part 79: Physico-chemical properties of piperidinoethyl esters of alkoxymethylcarbanilic acids.
Partition coefficients, pH's of turbidity, surface tensions of aqueous solutions, UV spectra and RF values of the adsorption TLC of the salts of 9 piperidinoethylesters of alkoxymethylcarbanilic acids were measured. The surface and infiltration local anesthetic activities of the compounds were correlated with the determined physico-chemical parameters.
D000779:Anesthetics, Local / Q000008:administration & dosage; D002219:Carbamates; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002855:Chromatography, Thin Layer; D006863:Hydrogen-Ion Concentration; D009391:Nephelometry and Turbidimetry; D010880:Piperidines / Q000008:administration & dosage; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship
D000779:Anesthetics, Local; D002219:Carbamates; D010880:Piperidines