title: Trace elements in chemical evolution, I.
abstract: Research on trace elements in chemical evolution is reviewed from three points of view. They are: the origin of the essentiality of trace elements in present biological systems; the possible roles of trace elements in chemical evolution; and the origin of enzymatic activity with metal ions, i.e., the origin of metalloenzymes.
mesh_terms: D000596:Amino Acids; D002413:Cations, Divalent; D010455:Peptides / Q000138:chemical synthesis; D012623:Seawater; D014131:Trace Elements
chemical_list: D000596:Amino Acids; D002413:Cations, Divalent; D010455:Peptides; D014131:Trace Elements