title: Structural abnormalities of the myenteric (Auerbach's) plexus in familial dysautonomia (Riley-Day syndrome) as demonstrated by flat-mount preparation of the esophagus and stomach.
abstract: The esophageal and gastric myenteric (Auerbach's) plexus were studied by a flat-mount preparation in 3 patients with familial dysautonomia. In 1 patient a typical esophageal network was found in the stomach. In another patient both esophageal and gastric plexus patterns were significantly different from normal. These changes, by producing abnormal nervous stimulation, may explain disturbed motility of the esophagus and stomach in familial dysautonomia.
mesh_terms: D002648:Child; D002675:Child, Preschool; D004402:Dysautonomia, Familial / Q000150:complications* / Q000473:pathology; D004947:Esophagus / Q000294:innervation; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009197:Myenteric Plexus / Q000002:abnormalities* / Q000473:pathology; D013270:Stomach / Q000294:innervation