Lectin histochemistry in a case of ulcerative colitis complicating rectal carcinoma.
The large bowel from a patient with ulcerative colitis complicating a rectal carcinoma was histochemically investigated by using two lectins; Ulex europaeus agglutinin-I (UEA-I) and peanut lectin (PNA). Much UEA-I binding glycoantigen and PNA binding glycoantigen appeared in the carcinoma and dysplastic lesion whereas only a small amount of both antigens was found in the non-dysplastic regenerating epithelium. Consequently, a very sharp contrast between the dysplastic lesion and non-dysplastic regenerating epithelium was demonstrated by the lectin staining.
D000230:Adenocarcinoma / Q000032:analysis* / Q000150:complications / Q000473:pathology; D000328:Adult; D000951:Antigens, Neoplasm / Q000032:analysis*; D003093:Colitis, Ulcerative / Q000150:complications / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007413:Intestinal Mucosa / Q000032:analysis / Q000473:pathology; D037102:Lectins / Q000378:metabolism; D008297:Male; D019887:Peanut Agglutinin; D037121:Plant Lectins; D012004:Rectal Neoplasms / Q000032:analysis* / Q000150:complications / Q000473:pathology
D000951:Antigens, Neoplasm; D037102:Lectins; D019887:Peanut Agglutinin; D037121:Plant Lectins; C036850:Ulex europaeus lectins