[Clinical study on aztreonam in pediatrics].
Efficacy and safety of aztreonam (AZT) for 31 cases of infections of children were studied with the following results. Clinical efficacy of AZT for 22 respiratory tract infections, 5 urinary tract infections and 2 gastrointestinal infections was "excellent" for 19 cases (65.5%), "good" for 9 cases (31.0%) and "poor" for 1 case (3.4%) with an overall effective rate of 96.6%. Microbiological effect of AZT for 19 isolated strains (15 cases) was 100% in disappearance of the Gram-negative bacteria and 89.5% on the whole. With regard to side effect of AZT in 31 cases, there was a slight elevation of GPT in 1 case and eosinophilia in 2 cases. It was considered from the above results that AZT is a useful and safe antibiotic for infections of children.
D000367:Age Factors; D001398:Aztreonam / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004751:Enteritis / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D001398:Aztreonam