[Nitrogenous triterpene derivatives. 10. Hemisuccinates of some oleanolic acid derivatives and their antiulcer effect].
The synthesis of hemisuccinates of some derivatives of oleanolic acid is reported, their inhibitory response to experimentally induced gastric ulcers in rats is examined. The hemisuccinates 13a (sodium salt of 13), 14 and 17 are more effective inhibitors than carbenoxolon-sodium.
D000818:Animals; D000897:Anti-Ulcer Agents / Q000138:chemical synthesis / Q000494:pharmacology; D008297:Male; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000494:pharmacology; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D012502:Sapogenins / Q000138:chemical synthesis / Q000494:pharmacology; D013276:Stomach Ulcer / Q000139:chemically induced / Q000517:prevention & control; D013329:Structure-Activity Relationship
D000897:Anti-Ulcer Agents; D012502:Sapogenins; D009828:Oleanolic Acid; D012110:Reserpine
Stickstoffhaltige Triterpenderivate. 10. Mitteilung: Hemisuccinate einiger Oleanolsäurederivate und deren Antiulkuswirkung.