Cervical myelography in dogs using iohexol.
Iohexol, a non-ionic water-soluble radiographic contrast medium, was used for cervical myelography in dogs (10-17 kg). The animals remained clinically normal following myelography, with no evidence of seizures. At 10 days after myelography there was a slight, but significant (p less than 0.05) increase in neutrophils in the cerebrospinal fluid; these cell numbers had returned to normal by the time of necropsy at 60 days after myelography. This investigation suggests that iohexol may be suitable for clinical myelography in the dog.
D000818:Animals; D002555:Cerebrospinal Fluid / Q000187:drug effects; D003287:Contrast Media / Q000009:adverse effects; D004285:Dogs; D004353:Drug Evaluation, Preclinical / Q000662:veterinary; D007463:Iodobenzoates; D007472:Iohexol; D009192:Myelography / Q000379:methods / Q000662:veterinary*; D013997:Time Factors; D014283:Triiodobenzoic Acids / Q000009:adverse effects
D003287:Contrast Media; D007463:Iodobenzoates; D014283:Triiodobenzoic Acids; D007472:Iohexol