Coexistence of simple and mixed bile salt-lecithin micelles: an NMR self-diffusion study.
The aggregation behavior of bile salt and lecithin in aqueous solutions at 20 degrees C was studied from bile salt, lecithin, and aggregate self-diffusion coefficients obtained by means of a Fourier-transform NMR pulsed-gradient spin-echo technique. The results strongly support the coexistence of simple bile salt micelles and mixed bile salt-lecithin micelles under physiologic conditions.
D001647:Bile Acids and Salts; D004058:Diffusion; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008433:Mathematics; D008954:Models, Biological; D010713:Phosphatidylcholines; D013656:Taurocholic Acid; D013657:Taurodeoxycholic Acid
D001647:Bile Acids and Salts; D010713:Phosphatidylcholines; D013657:Taurodeoxycholic Acid; D013656:Taurocholic Acid