An all-glass perfusator for investigation of the intestinal transport and metabolism of foreign compounds in vitro.
The in vitro perfusion technique of surviving intestinal segments as described by Fisher and Parsons (1949) and modified by Rummel and Stupp (1960) was further improved by the introduction of an all-glass perfusator for studying the intestinal transport and metabolism of lipophilic xenobiotics.
D000818:Animals; D002021:Buffers; D004573:Electrolytes / Q000378:metabolism; D005260:Female; D005947:Glucose / Q000378:metabolism; D007082:Ileum / Q000378:metabolism; D066298:In Vitro Techniques; D007408:Intestinal Absorption / Q000187:drug effects; D007413:Intestinal Mucosa / Q000378:metabolism*; D007583:Jejunum / Q000378:metabolism; D009602:Nitrosamines / Q000494:pharmacology; D010477:Perfusion / Q000295:instrumentation; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D002021:Buffers; D004573:Electrolytes; D009602:Nitrosamines; D004364:Pharmaceutical Preparations; D005947:Glucose