title: Locked-in syndrome with bilateral ptosis: combination of bilateral horizontal pontine gaze paralysis and nuclear oculomotor nerve paralysis.
abstract: A patient with a classical locked-in syndrome is described, in whom bilateral ptosis was observed on the 2nd day. On the 4th day, ophthalmoplegia was complete with the exception of a voluntary downward movement of the right eye. The syndrome can be explained by the association of bilateral horizontal pontine gaze palsy and a unilateral nuclear oculomotor nerve palsy, and approximates the "total locked-in syndrome".
mesh_terms: D000328:Adult; D001763:Blepharoptosis / Q000150:complications*; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000150:complications / Q000473:pathology; D003389:Cranial Nerve Diseases / Q000150:complications / Q000473:pathology; D005133:Eye Movements; D006801:Humans; D008297:Male; D009336:Necrosis; D009802:Oculomotor Nerve / Q000473:pathology; D009886:Ophthalmoplegia / Q000150:complications* / Q000503:physiopathology; D011149:Pons / Q000473:pathology; D011782:Quadriplegia / Q000150:complications*