Wegener's granulomatosis diagnosed by open lung biopsy.
A 21 year old man was diagnosed as having Wegener's granulomatosis at thoracotomy. Treatment with prednisolone and cyclophosphamide was initiated but the patient died 4 months later. Wegener's granulomatosis is a rare disease which should be considered in the differential diagnosis of pulmonary malignancies, tuberculosis and lung abscess. Early diagnosis is mandatory for a favourable outcome. Open lung biopsy is recommended, if other examinations have failed, as large representative biopsies can be obtained.
D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D014890:Granulomatosis with Polyangiitis / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis