Systemic candidiasis in premature infants experience with drug treatment.
Eleven premature infants with systemic candidiasis from 1981 to 1984 have been reported previously. The experience with antifungal drugs is presented. Amphotericin B at lower maintenance dose, together with 5 flucytosine (5FC), are the preferred drugs for treatment of systemic candidiasis at present.
D000666:Amphotericin B / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy*; D003596:Cytosine / Q000031:analogs & derivatives*; D004359:Drug Therapy, Combination; D005437:Flucytosine / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy*; D007654:Ketoconazole / Q000627:therapeutic use*; D008825:Miconazole / Q000627:therapeutic use*
D008825:Miconazole; D000666:Amphotericin B; D003596:Cytosine; D005437:Flucytosine; D007654:Ketoconazole