title: Nasal hypersensitivity in wood furniture workers.
abstract: Occupational nasal allergies were studied in six wood furniture factories. The concentration of moulds, wood dust and endotoxins was registered and occasionally high values were found. Paecilomyces spec. was the most common mould. A special questionnaire showed that 16% (42/268) of the wood workers with a mean exposure time of 12 years had a history compatible with hypersensitivity in the upper airways associated to their work. Rhinomanometric investigations showed mucosal congestion in the workers with nasal discomfort and nasal clearance was pathologically slow in 54%. Histological studies revealed a high incidence of unciliated and metaplastic nasal epithelium. Skin prick tests and provocation tests with standard allergens and allergens prepared from the moulds and the wood dust in the environment showed that the wood furniture workers had an incidence of allergy to moulds in 3% and to wood dust in 2%. Most of the workers sensitive to moulds and/or woods were also skin prick sensitive to other allergens. No statistical difference concerning the presence of precipitating antibodies against mould and wood antigens could be registered between workers with discomfort and workers without symptoms.
mesh_terms: D000391:Air Microbiology; D004731:Endotoxins / Q000032:analysis; D006090:Gram-Negative Bacteria / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology / Q000276:immunology*; D009181:Mycoses / Q000276:immunology; D009297:Nasal Mucosa / Q000276:immunology*; D009784:Occupational Diseases / Q000453:epidemiology / Q000276:immunology*; D012621:Seasons; D012882:Skin Tests; D011795:Surveys and Questionnaires; D013548:Sweden; D014934:Wood
chemical_list: D004731:Endotoxins