title: Cardiovascular responses to tracheal intubation in small children. Effects of the induction of anaesthesia with halothane.
abstract: Cardiovascular changes in 27 children (mean age 1.5 yr) were studied during the induction of anaesthesia with 2.5% halothane and 70% nitrous oxide in oxygen. The eyelash reflex disappeared in a mean of 62 +/- 3.6 (SEM)s and tracheal intubation could be performed 4.9 +/- 0.2 min after the start of halothane anaesthesia. Intubating conditions were satisfactory in 85% of the children. Systolic arterial pressure increased by 10.8 +/- 1.9 mm Hg and diastolic pressures by 6.0 +/- 1.4 (SEM) mm Hg after intubation of the trachea. Heart rate decreased significantly after induction. No cardiac arrhythmias were noted. There were no significant changes in Q-T interval after induction, after intubation or during the later course of the anaesthetic.
mesh_terms: D000769:Anesthesia, Inhalation; D005260:Female; D006221:Halothane / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal; D008297:Male; D013997:Time Factors
chemical_list: D006221:Halothane