title: IgM-associated mesangial proliferative glomerulonephritis and focal and segmental hyalinosis with nephrotic syndrome.
abstract: We present the case of an adult patient with the nephrotic syndrome. Morphologic and immunofluorescence studies revealed IgM-associated mesangial proliferative glomerulonephritis. On repeat biopsy, progression to focal glomerulosclerosis was noticed. The pathophysiological aspects of this evolution are discussed.
mesh_terms: D000368:Aged; D005921:Glomerulonephritis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M; D008297:Male; D009402:Nephrosis, Lipoid / Q000209:etiology / Q000473:pathology; D009404:Nephrotic Syndrome / Q000150:complications* / Q000209:etiology / Q000473:pathology
chemical_list: D007075:Immunoglobulin M