Morphology of embryonic neostriatal cell suspensions transplanted into adult neostriata.
Embryonic neostriatal cell suspensions were transplanted into intact or kainic acid-lesioned neostriata of adult host rats. These transplants survived and were sacrificed at 34-78 days posttransplantation. Nissl and Golgi preparations revealed neurons present within the transplants. Neurons with abundant dendritic spines (Spiny type I) were most frequent, but those with fewer spines (Spiny type II) and smooth dendrites (Aspiny II and III) were also present. These results indicate that neostriatal transplants are populated by the major output and internuncial neurons of the neostriatum.
D000818:Animals; D003342:Corpus Striatum / Q000187:drug effects / Q000196:embryology / Q000637:transplantation*; D007608:Kainic Acid / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
D007608:Kainic Acid