Isolation and hypoglycemic activity of panaxans Q, R, S, T and U, glycans of Panax ginseng roots.
From a water extract of the Oriental crude drug "ninjin" (ginseng), Panax ginseng roots from Nagano, Japan, five glycans, panaxans Q, R, S, T and U, have been obtained. These constituents displayed marked hypoglycemic action in normal and alloxan-induced hyperglycemic mice.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy; D004590:Electrophoresis, Paper; D004591:Electrophoresis, Polyacrylamide Gel; D007004:Hypoglycemic Agents; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D005894:Panax / Q000032:analysis*; D010946:Plants, Medicinal; D011134:Polysaccharides / Q000302:isolation & purification* / Q000494:pharmacology
D001786:Blood Glucose; D007004:Hypoglycemic Agents; D011134:Polysaccharides; C044185:panaxans