Unsuspected amyloidosis and cardiac arrest following mitral valve replacement.
We performed an autopsy on a 58-year-old female with previously unsuspected cardiac amyloidosis. One day prior to expiration the patient underwent a mitral valve replacement with a Bjork-Shiley prosthesis for mitral valve regurgitation. The valvular defect along with the massive myocardial amyloidosis which created a restrictive cardiomyopathy, were the etiology of the patient's poor cardiac output and subsequent demise.
D000686:Amyloidosis / Q000150:complications* / Q000473:pathology; D002313:Cardiomyopathy, Restrictive / Q000209:etiology* / Q000473:pathology; D005260:Female; D006323:Heart Arrest / Q000209:etiology*; D006350:Heart Valve Prosthesis; D006801:Humans; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000601:surgery*; D011183:Postoperative Complications