Survival after massive ingestion of carbon tetrachloride treated by intravenous infusion of acetylcysteine.
A 61-year-old man ingested a large amount of carbon tetrachloride, well in excess of the adult lethal dose. The level of the compound was assayed in his blood and the levels were the highest ever recorded by the Guy's Hospital Poisons Unit. He was treated by intravenous infusion of acetylcysteine and survived with relatively mild clinical and biochemical evidence of toxicity. Possible reasons for his survival are discussed, as are the implications for the management of future cases.
D000111:Acetylcysteine / Q000627:therapeutic use*; D001219:Aspartate Aminotransferases / Q000097:blood; D002251:Carbon Tetrachloride / Q000097:blood; D002252:Carbon Tetrachloride Poisoning / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D010001:Osteitis Deformans / Q000000981:diagnostic imaging / Q000201:enzymology; D011516:Prothrombin / Q000378:metabolism; D011618:Psychotic Disorders / Q000150:complications; D011859:Radiography; D013406:Suicide, Attempted
D011516:Prothrombin; D002251:Carbon Tetrachloride; D001219:Aspartate Aminotransferases; D000111:Acetylcysteine