Chronic inflammatory demyelinating polyneuropathy.
In 12 cases of CIDP under surveillance for 14 years, the main nerve biopsy findings were endoneural oedema and demyelination of nerve fibres. IgM deposition was found in 1 patient and IgG deposits in another. Electron microscopy revealed proliferation of the Schwann cells and mononuclear cell infiltration. The diagnostic criteria and nerve biopsy findings in CIDP are listed in the tables.
D000293:Adolescent; D000328:Adult; D001327:Autoimmune Diseases / Q000276:immunology / Q000473:pathology*; D002648:Child; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008854:Microscopy, Electron; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000276:immunology / Q000648:ultrastructure*; D010525:Peripheral Nerves / Q000276:immunology / Q000503:physiopathology* / Q000648:ultrastructure*; D011129:Polyradiculoneuropathy / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D012583:Schwann Cells / Q000473:pathology
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents