title: [Activity of urease in microcapsules].
abstract: The activity of urease in microcapsules formed by a symplex membrane from cellulose sulphate and polydimethyldiallyl ammonium chloride is studied and compared with that of free urease in solution. Both free and encapsulated urease exhibits a similar pH optimum. The interaction of urease with cellulose sulphate causes a decrease of the activity down to 35 to 38%. In spite of its lower absolute activity the encapsulated urease shows a higher long time stability than the free urease. The presented immobilization method for urease could be of importance for an active detoxification in uremia.
mesh_terms: D002214:Capsules; D002482:Cellulose / Q000031:analogs & derivatives; D004800:Enzymes, Immobilized / Q000008:administration & dosage* / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D011095:Polyethylenes; D011108:Polymers; D000644:Quaternary Ammonium Compounds; D014510:Urease / Q000008:administration & dosage* / Q000378:metabolism
chemical_list: D002214:Capsules; D004800:Enzymes, Immobilized; D011095:Polyethylenes; D011108:Polymers; D000644:Quaternary Ammonium Compounds; C041004:poly-N,N-dimethyl-N,N-diallylammonium chloride; D002482:Cellulose; C020254:cellulose sulfate; D014510:Urease
vernacular_title: Aktivitätseigenschaften von Urease in Mikrokapseln.