Detection of two ornithine carbamoyltransferases in a phaseolotoxin-producing strain Pseudomonas syringae pv. phaseolicola.
The phaseolotoxin-producing Pseudomonas syringae pv. phaseolicola strain 1321 contains two ornithine carbamoyltransferases which differ in resistance to phaseolotoxin. Whereas ornithine carbamoyltransferase 1 (OCT 1) is inhibited at low concentrations of phaseolotoxin, ornithine carbamoyltransferase 2 (OCT 2) is insensitive to phaseolotoxin. The activity of the insensitive enzyme is correlated with the amount of toxin formed.
D005098:Exotoxins / Q000096:biosynthesis*; D007527:Isoenzymes / Q000302:isolation & purification / Q000378:metabolism*; D007700:Kinetics; D009952:Ornithine / Q000031:analogs & derivatives; D009954:Ornithine Carbamoyltransferase / Q000037:antagonists & inhibitors / Q000302:isolation & purification / Q000378:metabolism*; D011549:Pseudomonas / Q000201:enzymology / Q000378:metabolism*
D005098:Exotoxins; D007527:Isoenzymes; C021234:phaseolotoxin; D009952:Ornithine; D009954:Ornithine Carbamoyltransferase