[Characteristics of the functional activity of leukocytes in diabetes mellitus].
A study was made of the mechanisms of leucocyte phagocytic and bactericidal activity with relation to Staph, aureus and the NBT-test in simple and simulated variants in 71 patients with diabetes mellitus. A compensatory elevation of the phagocytic index and the phagocytic number was found in all the patients with a decrease in phagocytosis completion which testified to the internal defects of bactericidal activity which, according to the NBT-test results, consisted in insufficient activity of oxidation enzymes. The stimulated NBT-test showed a decrease in phagocytic potentialities in patients with diabetes mellitus. Phagocytosis defects in type I and type II diabetes mellitus were more noticeable in a severe and labile course of the disease.
D000293:Adolescent; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D003924:Diabetes Mellitus, Type 2 / Q000276:immunology*; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*; D009580:Nitroblue Tetrazolium; D010585:Phagocyte Bactericidal Dysfunction / Q000175:diagnosis / Q000209:etiology*; D010587:Phagocytosis; D013211:Staphylococcus aureus / Q000276:immunology
D009580:Nitroblue Tetrazolium
K osobennostiam funktsional'noĭ aktivnosti leĭkotsitov pri sakharnom diabete.