The relationship between the lipophilic nature of tricyclic neuroleptics and antidepressants, and histamine release.
D000639:Amitriptyline / Q000494:pharmacology; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D002463:Cell Membrane Permeability / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002746:Chlorpromazine / Q000494:pharmacology; D002749:Chlorprothixene / Q000494:pharmacology; D003006:Clopenthixol / Q000494:pharmacology; D003891:Desipramine / Q000494:pharmacology; D005476:Fluphenazine / Q000494:pharmacology; D006636:Histamine Release / Q000187:drug effects*; D007099:Imipramine / Q000494:pharmacology; D007700:Kinetics; D008297:Male; D008407:Mast Cells / Q000187:drug effects; D008728:Methotrimeprazine / Q000494:pharmacology; D009661:Nortriptyline / Q000494:pharmacology; D010546:Perphenazine / Q000494:pharmacology; D010640:Phenothiazines / Q000494:pharmacology; D011346:Prochlorperazine / Q000494:pharmacology; D011395:Promazine / Q000494:pharmacology; D011398:Promethazine / Q000494:pharmacology; D051381:Rats; D012997:Solvents; D013329:Structure-Activity Relationship; D013881:Thioridazine / Q000494:pharmacology; D014149:Tranquilizing Agents / Q000494:pharmacology*; D014268:Trifluoperazine / Q000494:pharmacology
D000928:Antidepressive Agents; D010640:Phenothiazines; D012997:Solvents; D014149:Tranquilizing Agents; D000639:Amitriptyline; D014268:Trifluoperazine; D003006:Clopenthixol; D008728:Methotrimeprazine; D002749:Chlorprothixene; D009661:Nortriptyline; D011398:Promethazine; D010546:Perphenazine; D013881:Thioridazine; D011395:Promazine; D007099:Imipramine; D005476:Fluphenazine; D003891:Desipramine; D002746:Chlorpromazine; D011346:Prochlorperazine