Intestinal coccidiosis in a patient with alpha-chain disease.
During an ultrastructural study of small-intestinal mucosa from a patient suffering from alpha-chain disease organisms were identified within the epithelial cytoplasm which showed the fine structural features of the coccidian group. Though coccidiosis is well recognized as causing a diarrhoeal and often lethal illness in animals it has been neglected as a cause of disease in man. Thus this finding may be significant and warrants further investigation into its possible role in the pathogenesis of alpha-chain disease.
D000328:Adult; D001796:Blood Protein Disorders / Q000150:complications* / Q000473:pathology; D003048:Coccidiosis / Q000150:complications*; D003593:Cytoplasm; D004848:Epithelium; D006801:Humans; D007128:Immunoglobulin Fragments; D007410:Intestinal Diseases / Q000150:complications* / Q000473:pathology; D007413:Intestinal Mucosa / Q000382:microbiology / Q000473:pathology; D007421:Intestine, Small / Q000382:microbiology / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D005719:gamma-Globulins
D007128:Immunoglobulin Fragments; D005719:gamma-Globulins