The diagnosis of Hodgkin's disease in surgically excised spleens.
A series of 44 spleens removed from patients with Hodgkin's disease before treatment has been reviewed. The difficulties encountered in detecting foci of Hodgkin's tissue and the histological features and characteristics of early invasion are described.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006099:Granuloma / Q000473:pathology; D006644:Histiocytes; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D013154:Spleen / Q000473:pathology*; D013156:Splenectomy; D013194:Staining and Labeling