title: Acute submassive hepatic necrosis due to methyldopa. A case demonstrating possible initiation of chronic liver disease.
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001707:Biopsy, Needle; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D004796:Clinical Enzyme Tests; D003298:Coombs Test; D004562:Electrocardiography; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy; D008099:Liver / Q000473:pathology; D008750:Methyldopa / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D009336:Necrosis; D009504:Neutrophils; D012110:Reserpine / Q000627:therapeutic use
chemical_list: D006852:Hydrochlorothiazide; D008750:Methyldopa; D012110:Reserpine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase