A method for the isolation and purification of normal rat liver and hepatoma nuclear "ghosts" by zonal centrifugation.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D002458:Cell Fractionation; D002467:Cell Nucleus; D002499:Centrifugation, Density Gradient; D002501:Centrifugation, Zonal; D004247:DNA / Q000032:analysis; D005260:Female; D005374:Filtration; D007038:Hypotonic Solutions; D008099:Liver / Q000032:analysis / Q000166:cytology*; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008566:Membranes; D008722:Methods; D008854:Microscopy, Electron; D008858:Microscopy, Phase-Contrast; D009374:Neoplasms, Experimental; D011506:Proteins / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D013053:Spectrophotometry; D013194:Staining and Labeling
D007038:Hypotonic Solutions; D011506:Proteins; D004247:DNA