title: Cryptococcus neoformans of unusual morphology.
abstract: A case of primary cryptococcosis of the lungs was caused by an isolate of Cryptococcus neoformans that assumes a giant form in tissue but which has a normal appearance on artificial culture. Electron microscopy revealed gross enlargement of the capsule and plasma membranes in the tissue form.
mesh_terms: D001706:Biopsy; D002473:Cell Wall; D003453:Cryptococcosis / Q000473:pathology*; D003454:Cryptococcus / Q000166:cytology* / Q000302:isolation & purification; D003455:Cryptococcus neoformans / Q000166:cytology; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008168:Lung / Q000382:microbiology / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000473:pathology*; D008854:Microscopy, Electron; D008858:Microscopy, Phase-Contrast; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000473:pathology*; D013194:Staining and Labeling; D013492:Suppuration / Q000382:microbiology