title: Reversible inactivation of the deoxyribonucleic acid polymerase of Rauscher leukemia virus.
abstract: Rauscher leukemia virus deoxyribonucleic acid polymerase is reversibly inactivated by 6 m guanidine-hydrochloride. Gel filtration in 6 m guanidine-hydrochloride reveals that the viral deoxyribonucleic acid polymerase consists of a single polypeptide chain of approximately 70,000 molecular weight.
mesh_terms: D001358:Avian Sarcoma Viruses / Q000201:enzymology; D002850:Chromatography, Gel; D003956:Dialysis; D004229:Dithiothreitol; D004794:Enzyme Repression; D006146:Guanidines / Q000494:pharmacology*; D005256:Leukemia Virus, Feline / Q000201:enzymology; D008970:Molecular Weight; D011189:Potassium Chloride; D012194:RNA-Directed DNA Polymerase / Q000032:analysis / Q000302:isolation & purification / Q000378:metabolism*; D011925:Rauscher Virus / Q000201:enzymology*; D012710:Serum Albumin, Bovine; D013501:Surface-Active Agents
chemical_list: D006146:Guanidines; D013501:Surface-Active Agents; D012710:Serum Albumin, Bovine; D011189:Potassium Chloride; D012194:RNA-Directed DNA Polymerase; D004229:Dithiothreitol