Ferritin particles in macrophages and in associated mast cells.
In a variety of tissues (lymph node and glandular stroma), mast cells have been found in close and often intimate association with macrophages containing numerous ferritin-like particles in their cytoplasm and within cytoplasmic vacuoles (siderosomes). Phagocytic vacuoles in a given macrophage differed markedly. Some contained abundant Prussian blue-reactive material and others contained periodic acid-Schiff reactive substance at the light microscope level, and ultrastructurally some were filled with ferritin particles and others were not. Ferritin-like particles have also been observed occasionally in the mast cells associated with macrophages and even within the matrix of some of the granules in these mast cells.
D000818:Animals; D005260:Female; D005293:Ferritins / Q000032:analysis*; D006651:Histocytochemistry; D008198:Lymph Nodes / Q000166:cytology; D008264:Macrophages / Q000032:analysis*; D008407:Mast Cells / Q000032:analysis*; D008854:Microscopy, Electron; D010504:Periodic Acid; D051381:Rats; D012469:Salivary Glands / Q000166:cytology; D013194:Staining and Labeling
D010504:Periodic Acid; D005293:Ferritins