Relation of measles virus to encephalitogenic factor with reference to the aetiopathogenesis of multiple sclerosis.
A combination of affinity chromatography with the macrophage electrophoretic migration (MEM) test has been used to study the antigenic similarities between encephalitogenic factor (EF) and measles virus. These have determinant(s) sufficiently closely related to account for the elevated level of circulating antibody to measles in multiple sclerosis.
D000914:Antibodies, Viral; D001666:Binding Sites, Antibody; D002464:Cell Migration Inhibition; D002648:Child; D002846:Chromatography, Affinity; D000939:Epitopes; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008459:Measles virus / Q000276:immunology*; D009103:Multiple Sclerosis / Q000209:etiology* / Q000276:immunology; D004676:Myelin Basic Protein; D012897:Slow Virus Diseases / Q000276:immunology
D000914:Antibodies, Viral; D000939:Epitopes; D004676:Myelin Basic Protein