The isolation from spleen tissue of high molecular weight proteins which alter vascular permeability: investigation of their chemical and pharmacological properties.
D000645:Ammonium Sulfate; D000818:Animals; D001808:Blood Vessels / Q000187:drug effects*; D002199:Capillary Permeability; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D003956:Dialysis; D004305:Dose-Response Relationship, Drug; D006636:Histamine Release / Q000187:drug effects; D007525:Isoelectric Focusing; D008784:Methysergide / Q000494:pharmacology; D008970:Molecular Weight; D010539:Permeability; D011506:Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D051381:Rats; D012701:Serotonin / Q000378:metabolism; D012867:Skin / Q000098:blood supply; D013154:Spleen; D013997:Time Factors; D014020:Tissue Extracts / Q000494:pharmacology*
D011506:Proteins; D014020:Tissue Extracts; D012701:Serotonin; D000645:Ammonium Sulfate; D008784:Methysergide