Absence of leukosis virus markers in hamster cells transformed by herpes simplex virus type 2.
Hamster cells which transformed after exposure to herpes simplex virus type 2 previously irradiated with ultraviolet light were tested for the presence of hamster leukosis viruses or their virus-specific antigens. Three techniques that were used did not detect the presence of either hamster C-type particles or antigens commonly associated with such structures. The implication of these findings to current concepts of virus oncology is discussed.
D000818:Animals; D000956:Antigens, Viral / Q000302:isolation & purification; D001973:Bromodeoxyuridine; D002460:Cell Line / Q000276:immunology / Q000382:microbiology; D002467:Cell Nucleus / Q000382:microbiology; D002471:Cell Transformation, Neoplastic; D002499:Centrifugation, Density Gradient; D006224:Cricetinae; D003593:Cytoplasm / Q000382:microbiology; D005347:Fibroblasts; D005455:Fluorescent Antibody Technique; D007181:Inclusion Bodies, Viral; D008854:Microscopy, Electron; D012328:RNA Viruses / Q000276:immunology / Q000302:isolation & purification*; D011830:Radiation Effects; D012190:Retroviridae / Q000276:immunology / Q000302:isolation & purification*; D012703:Serotyping; D018139:Simplexvirus / Q000254:growth & development* / Q000528:radiation effects; D013194:Staining and Labeling; D014316:Tritium; D014466:Ultraviolet Rays; D014529:Uridine
D000956:Antigens, Viral; D014316:Tritium; D001973:Bromodeoxyuridine; D014529:Uridine