Hepatitis B virus antigen: validation and immunologic characterization of low-titer serums with  125 I-antibody.
Radioimmunnoassay was used to determine the serologic subspecificities of 85 blood donor serums positive for hepatitis B virus-associated antigen. There was complete agreement with results obtained by immunoprecipitatiotn of 43 serums. The remaining 42 serums were negative by immunoprecipitation but followed type-specific immunology by radioimmunoassay, and this served as a validation for authentic hepatitis B virus antigen.
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification; D000918:Antibody Specificity; D001782:Blood Donors; D000939:Epitopes; D006168:Guinea Pigs / Q000276:immunology; D006511:Hepatitis B Antigens / Q000032:analysis*; D006801:Humans; D005779:Immunodiffusion; D007456:Iodine Isotopes; D011233:Precipitin Tests; D011863:Radioimmunoassay
D000906:Antibodies; D000939:Epitopes; D006511:Hepatitis B Antigens; D007456:Iodine Isotopes