Titration of adenovirus by counting cells containing virus-induced inclusion bodies.
A new method for the titration of adenovirus types 2 and 12 based on the enumeration of viral inclusions in infected cells was devised and evaluated. The technique gave virus titers comparable to those obtained by the plaque assay procedure.
D000256:Adenoviridae / Q000254:growth & development / Q000302:isolation & purification*; D002277:Carcinoma; D002452:Cell Count; D002460:Cell Line / Q000382:microbiology; D002478:Cells, Cultured / Q000382:microbiology; D006801:Humans; D007181:Inclusion Bodies, Viral; D007822:Laryngeal Neoplasms; D008722:Methods; D012703:Serotyping; D013194:Staining and Labeling; D014776:Virus Cultivation