Occurrence of a theta-like antigen in rats.
A rat antigen system parallel to the mouse theta system has been described(*) All rat strains tested expressed an antigen cross-reactive with the theta-AKR specificity of mice while none cross-reacted strongly with theta-C3H. The rat antigen may be demonstrated by either absorption or direct complement-mediated killing of rat thymocytes. Patterns of organ distribution and developmental appearance in the nervous system of rats also parallel those previously reported for theta in mice.
D000818:Animals; D000941:Antigens; D003165:Complement System Proteins; D003429:Cross Reactions; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D007106:Immune Sera; D007114:Immunization; D051379:Mice; D008806:Mice, Inbred AKR; D008809:Mice, Inbred C3H; D011817:Rabbits / Q000276:immunology; D051381:Rats; D011919:Rats, Inbred Strains / Q000276:immunology*; D013045:Species Specificity; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D000939:Epitopes; D007106:Immune Sera; D003165:Complement System Proteins