In situ hybridization of RD114-virus RNA with human metaphase chromosomes.
In situ hybridization was used to detect regions of human metaphase chromosomes exhibiting complementarity with radioactively-labeled RNA isolated from RD114-virus. The region of homology, as identified by autoradiography, was confined to one D-group chromosome.
D002499:Centrifugation, Density Gradient; D002875:Chromosomes / Q000032:analysis*; D002901:Chromosomes, Human, 13-15; D004279:DNA, Viral / Q000302:isolation & purification* / Q000378:metabolism; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000032:analysis / Q000166:cytology; D008938:Mitosis; D009374:Neoplasms, Experimental / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D012328:RNA Viruses / Q000032:analysis / Q000201:enzymology / Q000302:isolation & purification; D012367:RNA, Viral / Q000302:isolation & purification / Q000378:metabolism; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D012208:Rhabdomyosarcoma / Q000382:microbiology; D014316:Tritium
D004279:DNA, Viral; D012367:RNA, Viral; D014316:Tritium; D012194:RNA-Directed DNA Polymerase