title: Naturally occurring R factor, derepressed for pilus synthesis, belonging to the same compatibility group as the sex factor F of Escherichia coli K-12.
abstract: A naturally occurring R factor with constitutive pilus synthesis is described which resembles the sex factor F in compatibility and in restricting coliphage T7. Unlike F, it is not cured during growth with acridine orange. Results suggest that the R factor produces repressor of pilus synthesis, to which the operator is insensitive (i(+)o(c)). In this respect it differs from both the F factor (i(-)o(+)) and wild-type F-like R factors (i(+)o(+)).
mesh_terms: D000166:Acridines / Q000494:pharmacology; D001431:Bacteriological Techniques; D002701:Chloramphenicol / Q000494:pharmacology; D003090:Coliphages; D003227:Conjugation, Genetic; D003470:Culture Media; D004269:DNA, Bacterial; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects* / Q000254:growth & development; D005809:Genes, Regulator; D005827:Genetics, Microbial; D007612:Kanamycin / Q000494:pharmacology; D008854:Microscopy, Electron; D009268:Nalidixic Acid / Q000494:pharmacology; D010772:Phosphotungstic Acid; D012343:RNA, Transfer; D013194:Staining and Labeling; D013752:Tetracycline / Q000494:pharmacology; D013778:Tetrazolium Salts; D014161:Transduction, Genetic
chemical_list: D000166:Acridines; D003470:Culture Media; D004269:DNA, Bacterial; D013778:Tetrazolium Salts; D010772:Phosphotungstic Acid; D009268:Nalidixic Acid; D007612:Kanamycin; D002701:Chloramphenicol; D012343:RNA, Transfer; D013752:Tetracycline