Human fetal cerebellar cortex: organization and maturation of cells in vitro.
Human fetal cerebellar cortex was maintained up to 5 months in vitro. Important features included early migration of granule neurons followed by maturation of Purkinje and granule neurons. Unique areas of organization developed in which a rim of leptomeningeal cells surrounded an explant and its outgrowth zone; these areas subsequently grew as well-defined units.
D002467:Cell Nucleus; D002525:Cerebellar Cortex / Q000166:cytology / Q000196:embryology*; D046508:Culture Techniques; D003593:Cytoplasm; D005865:Gestational Age; D006801:Humans; D008854:Microscopy, Electron; D008928:Mitochondria; D009457:Neuroglia / Q000166:cytology; D009474:Neurons / Q000166:cytology; D011689:Purkinje Cells / Q000166:cytology; D013194:Staining and Labeling