title: Dextrans and glycogens as particulate tracers for studying capillary permeability.
abstract: Commercially available glycogens and dextrans can be used as biological particulate tracers in work on capillary permeability. These polysaccharides are well tolerated in intravenous injection and induce no vascular leakage when applied topically (cremaster test) in mice and in Wistar-Furth rats. The particles stain adequately with lead after aldehyde-OsO(4) fixation in phosphate buffer and provide a relatively wide set of probes ( approximately 45 A-300 A) for work on the large and small pore systems.
mesh_terms: D000818:Animals; D002196:Capillaries / Q000032:analysis / Q000166:cytology; D002199:Capillary Permeability; D003911:Dextrans / Q000097:blood; D006003:Glycogen / Q000097:blood; D006651:Histocytochemistry; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D007413:Intestinal Mucosa / Q000166:cytology; D007583:Jejunum / Q000166:cytology; D008112:Liver Glycogen / Q000097:blood; D008297:Male; D008722:Methods; D051379:Mice; D008854:Microscopy, Electron; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D012758:Shellfish; D013194:Staining and Labeling
chemical_list: D003911:Dextrans; D008112:Liver Glycogen; D006003:Glycogen