title: Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity.
abstract: The relatedness of the RNAs of the three avian systems, including six avian leukosis-sarcoma viruses, four reticuloendotheliosis viruses, and the microsome fraction of normal uninfected chicken embryo cells, containing RNA and a DNA polymerase have been studied by nucleic acid hybridization. All six avian leukosis-sarcoma viruses have closely related nucleotide sequences; and all four reticuloendotheliosis viruses have closely related nucleotide sequences. But, almost no similarities were detected between the RNAs of avian leukosis-sarcoma viruses and reticuloendotheliosis viruses. The RNA template of the endogenous RNA-directed DNA polymerase activity of normal uninfected chicken cells had no detectable relationship to RNAs of avian leukosis-sarcoma and reticuloendotheliosis viruses.
mesh_terms: D001355:Alpharetrovirus / Q000032:analysis* / Q000201:enzymology / Q000254:growth & development; D000818:Animals; D001483:Base Sequence; D001717:Birds; D002642:Chick Embryo / Q000032:analysis; D046508:Culture Techniques; D004279:DNA, Viral / Q000096:biosynthesis; D008861:Microsomes / Q000032:analysis; D009693:Nucleic Acid Hybridization; D010761:Phosphorus Radioisotopes; D012313:RNA / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*; D051381:Rats; D013698:Templates, Genetic; D014158:Transcription, Genetic; D014316:Tritium
chemical_list: D004279:DNA, Viral; D010761:Phosphorus Radioisotopes; D012367:RNA, Viral; D014316:Tritium; D012313:RNA; D012194:RNA-Directed DNA Polymerase