title: Thymoma, myasthenia gravis, erythroblastopenic anemia and systemic lupus erythematosus in one patient.
abstract: A 50-year-old woman who initially had myasthenia gravis subsequently presented with thymoma, erythroblastopenic anemia and systemic lupus erythematosus during 17 years of follow-up. In a review of the literature no similar documented cases were found, although 14 patients were reported with three of the above diseases, two also having positive LE cell tests. An association of several autoimmune disorders in one patient may be more frequent than was previously believed.
mesh_terms: D000549:Ambenonium Chloride / Q000627:therapeutic use; D000741:Anemia, Aplastic / Q000150:complications*; D001327:Autoimmune Diseases / Q000209:etiology; D001853:Bone Marrow / Q000473:pathology; D001854:Bone Marrow Cells; D001996:Bronchopneumonia / Q000473:pathology; D005132:Eye Manifestations; D005260:Female; D006486:Hemosiderosis / Q000473:pathology; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000150:complications*; D008476:Mediastinal Cyst / Q000473:pathology; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications* / Q000188:drug therapy; D009388:Neostigmine / Q000627:therapeutic use; D009504:Neutrophils; D011241:Prednisone / Q000097:blood; D012008:Recurrence; D012156:Reticulocytes / Q000187:drug effects; D013945:Thymoma / Q000150:complications* / Q000532:radiotherapy; D013950:Thymus Gland / Q000276:immunology; D013953:Thymus Neoplasms / Q000150:complications* / Q000532:radiotherapy
chemical_list: D009388:Neostigmine; D000549:Ambenonium Chloride; D011241:Prednisone