Role of protein A in the serum-soft agar technique.
Formation of compact colonies of Staphylococcus aureus in serum-soft agar is mainly a result of a reaction between protein A and the Fc-part of immunoglobulin G and not a clumping factor-fibrinogen reaction.
D000362:Agar; D000371:Agglutination; D000818:Animals; D001426:Bacterial Proteins / Q000032:analysis; D002848:Chromatography, DEAE-Cellulose; D003470:Culture Media; D005340:Fibrinogen; D006358:Hot Temperature; D006801:Humans; D007106:Immune Sera; D007122:Immunoelectrophoresis; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011817:Rabbits / Q000276:immunology; D013194:Staining and Labeling; D013210:Staphylococcus / Q000254:growth & development*
D001426:Bacterial Proteins; D003470:Culture Media; D007106:Immune Sera; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D005340:Fibrinogen; D000362:Agar