Activation of lysosomal enzymes in rabies-infected tissue culture cells without accompanying cytopathic effect.
Lactic dehydrogenase and beta-glucuronidase were assayed in tissue culture fluids and cellular lysates, respectively, from BHK-21/13S and Iota cell cultures infected with rabies virus. Activation of lysosomal enzymes was shown from the day 4 of infection on, without any indication of cytopathic effect.
D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured / Q000382:microbiology*; D006224:Cricetinae; D003588:Cytopathogenic Effect, Viral; D004789:Enzyme Activation; D005455:Fluorescent Antibody Technique; D005966:Glucuronidase / Q000032:analysis*; D007668:Kidney; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D008247:Lysosomes / Q000201:enzymology*; D011820:Rabies virus; D013053:Spectrophotometry; D013194:Staining and Labeling
D007770:L-Lactate Dehydrogenase; D005966:Glucuronidase