title: Immunochemical studies on blood groups. LIV. Classification of anti-I and anti-i sera into groups based on reactivity patterns with various antigens related to the blood group A,B,H, Le a, Le b and precursor substances.
abstract: Quantitative precipitin assays were carried out with eleven anti-I and five anti-i cold agglutinin sera. Their reaction patterns with precursor substances and with certain antigens related to the A, B, H, Le(a), and Le(b) substances revealed at least six types of I and four types of i specificity. All of the I and i determinants appear to be represented in varying amounts on that fraction of the ovarian cyst precursor substance OG which was precipitated by 20% ethanol (OG 20% 2X). Only some of these determinants can be detected in the first periodate oxidation stages of A, B, and H substances, in cow substances, and in hydatid cyst fluid.
mesh_terms: D000017:ABO Blood-Group System; D000743:Anemia, Hemolytic / Q000276:immunology; D000906:Antibodies / Q000032:analysis*; D000918:Antibody Specificity; D001789:Blood Group Antigens; D004443:Echinococcosis / Q000276:immunology; D000939:Epitopes / Q000037:antagonists & inhibitors*; D005260:Female; D006801:Humans; D007106:Immune Sera / Q000145:classification*; D007120:Immunochemistry; D007983:Lewis Blood Group Antigens; D008895:Milk, Human / Q000276:immunology; D009175:Mycoplasma Infections / Q000276:immunology; D009844:Oligosaccharides; D010048:Ovarian Cysts / Q000276:immunology; D011233:Precipitin Tests
chemical_list: D000017:ABO Blood-Group System; D000906:Antibodies; D001789:Blood Group Antigens; D000939:Epitopes; D007106:Immune Sera; D007983:Lewis Blood Group Antigens; D009844:Oligosaccharides