Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives.
D001412:Bacillus subtilis / Q000187:drug effects; D001681:Biological Assay; D055598:Chemical Phenomena; D002621:Chemistry; D002852:Chromatography, Ion Exchange; D002854:Chromatography, Paper; D003511:Cyclohexanols; D004096:Dihydrostreptomycin Sulfate; D004355:Drug Stability; D006146:Guanidines; D010756:Phosphoric Acids / Q000302:isolation & purification / Q000494:pharmacology; D010744:Phosphoric Monoester Hydrolases; D010770:Phosphotransferases; D013045:Species Specificity; D013237:Stereoisomerism; D013302:Streptomyces / Q000201:enzymology*; D013305:Streptomyces griseus / Q000201:enzymology; D013307:Streptomycin / Q000302:isolation & purification / Q000494:pharmacology; D013329:Structure-Activity Relationship
D003511:Cyclohexanols; D006146:Guanidines; D010756:Phosphoric Acids; D010770:Phosphotransferases; D010744:Phosphoric Monoester Hydrolases; D004096:Dihydrostreptomycin Sulfate; D013307:Streptomycin