A model for the in vitro inhibition of the DNa polymerase reaction with the base specific antibiotics chromomycin-A 3'  actinomycin-C 3  and daunomycin.
D000255:Adenosine Triphosphate; D000818:Animals; D000903:Antibiotics, Antineoplastic; D001665:Binding Sites; D002247:Carbon Isotopes; D002384:Catalysis; D002417:Cattle; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002865:Chromomycins; D003090:Coliphages; D003597:Cytosine Nucleotides; D004247:DNA; D004254:DNA Nucleotidyltransferases / Q000037:antagonists & inhibitors*; D004269:DNA, Bacterial; D004279:DNA, Viral; D003609:Dactinomycin; D003630:Daunorubicin; D011756:Diphosphates; D004926:Escherichia coli / Q000201:enzymology*; D006150:Guanine Nucleotides; D008837:Micrococcus; D010759:Phosphorus Isotopes; D011119:Polynucleotides; D011485:Protein Binding; D013698:Templates, Genetic; D013950:Thymus Gland
D000903:Antibiotics, Antineoplastic; D002247:Carbon Isotopes; D002865:Chromomycins; D003597:Cytosine Nucleotides; D004269:DNA, Bacterial; D004279:DNA, Viral; D011756:Diphosphates; D006150:Guanine Nucleotides; D010759:Phosphorus Isotopes; D011119:Polynucleotides; D003609:Dactinomycin; D000255:Adenosine Triphosphate; D004247:DNA; D004254:DNA Nucleotidyltransferases; D003630:Daunorubicin