title: Reduction and reoxidation of Australia antigen: loss and reconstitution of particle structure and antigenicity.
abstract: Reduction of Australia antigen with dithiothreitol resulted in the loss of antigenicity and morphological integrity. Oxidation of the reduced Australia antigen reconstituted both of these characters.
mesh_terms: D000081:Acetamides; D000477:Alkylating Agents; D000478:Alkylation; D002499:Centrifugation, Density Gradient; D002586:Cesium; D002712:Chlorides; D002848:Chromatography, DEAE-Cellulose; D003956:Dialysis; D004229:Dithiothreitol; D006511:Hepatitis B Antigens / Q000302:isolation & purification; D006515:Hepatitis B virus / Q000276:immunology*; D007461:Iodoacetates; D008854:Microscopy, Electron; D010084:Oxidation-Reduction; D010772:Phosphotungstic Acid; D013194:Staining and Labeling; D013395:Sucrose
chemical_list: D000081:Acetamides; D000477:Alkylating Agents; D002712:Chlorides; D006511:Hepatitis B Antigens; D007461:Iodoacetates; D010772:Phosphotungstic Acid; D002586:Cesium; D013395:Sucrose; D004229:Dithiothreitol