title: An abnormality of the alternate pathway of complement activation in sickle-cell disease.
mesh_terms: D000293:Adolescent; D000328:Adult; D000372:Agglutination Tests; D000755:Anemia, Sickle Cell / Q000276:immunology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D001424:Bacterial Infections / Q000209:etiology; D002118:Calcium; D002648:Child; D002675:Child, Preschool; D003168:Complement Fixation Tests; D003165:Complement System Proteins / Q000032:analysis; D006018:Glycols / Q000494:pharmacology; D006801:Humans; D007106:Immune Sera; D007122:Immunoelectrophoresis; D007153:Immunologic Deficiency Syndromes / Q000209:etiology*; D007223:Infant; D008274:Magnesium; D009895:Opsonin Proteins; D010587:Phagocytosis; D011414:Properdin; D011485:Protein Binding; D011817:Rabbits / Q000276:immunology; D013296:Streptococcus pneumoniae / Q000276:immunology; D015054:Zymosan / Q000494:pharmacology
chemical_list: D000907:Antibodies, Bacterial; D006018:Glycols; D007106:Immune Sera; D009895:Opsonin Proteins; D011414:Properdin; D003165:Complement System Proteins; D015054:Zymosan; D008274:Magnesium; D002118:Calcium