Comparison of the antihistaminic effects in skin of a tertiary (promethazine) and a quarternary phenothiazine (N-hydroxyethylpromethazine).
D000293:Adolescent; D000328:Adult; D004341:Drug Evaluation; D006632:Histamine / Q000494:pharmacology; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D006801:Humans; D007279:Injections, Subcutaneous; D008875:Middle Aged; D010640:Phenothiazines / Q000494:pharmacology*; D010919:Placebos; D011398:Promethazine / Q000494:pharmacology*; D011537:Pruritus / Q000139:chemically induced; D012867:Skin / Q000187:drug effects*; D012882:Skin Tests; D013607:Tablets; D014357:Trypsin / Q000494:pharmacology
D006634:Histamine H1 Antagonists; D010640:Phenothiazines; D010919:Placebos; D013607:Tablets; D006632:Histamine; D014357:Trypsin; D011398:Promethazine