Evidence that punctate intracerebral administration of 6-hydroxydopamine fails to produce selective neuronal degeneration. Comparison with copper sulfate and factors governing the deportment of fluids injected into brain.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001921:Brain / Q000033:anatomy & histology / Q000201:enzymology / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects; D002395:Catecholamines / Q000502:physiology; D002800:Cholinesterase Inhibitors / Q000494:pharmacology; D003300:Copper / Q000494:pharmacology*; D005260:Female; D006892:Hydroxydopamines / Q000008:administration & dosage / Q000494:pharmacology*; D007267:Injections; D009186:Myelin Sheath / Q000032:analysis; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D009410:Nerve Degeneration / Q000187:drug effects*; D009474:Neurons / Q000032:analysis; D011699:Putamen; D051381:Rats; D012012:Red Nucleus / Q000033:anatomy & histology; D013238:Stereotaxic Techniques; D013378:Substantia Nigra; D013431:Sulfates / Q000494:pharmacology; D013681:Tegmentum Mesencephali; D013788:Thalamus
D002395:Catecholamines; D002800:Cholinesterase Inhibitors; D006892:Hydroxydopamines; D013431:Sulfates; D003300:Copper; D009247:NADH, NADPH Oxidoreductases