II. Enhancement of the catalytic activity of the human placental 17 beta-oestradiol dehydrogenase by carboxymethylation of an histidyl residue of the active site.
D000478:Alkylation; D001665:Binding Sites / Q000187:drug effects; D002021:Buffers; D002250:Carbon Radioisotopes; D002606:Charcoal; D004958:Estradiol; D005260:Female; D006639:Histidine / Q000378:metabolism*; D006801:Humans; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D066298:In Vitro Techniques; D007700:Kinetics; D008745:Methylation; D009249:NADP / Q000378:metabolism; D010920:Placenta / Q000201:enzymology*; D011247:Pregnancy; D013997:Time Factors; D014316:Tritium
D002021:Buffers; D002250:Carbon Radioisotopes; D014316:Tritium; D002606:Charcoal; D006639:Histidine; D004958:Estradiol; D009249:NADP; D006913:Hydroxysteroid Dehydrogenases