Cardiospecificity of  -receptor blockade. A comparison of the relative potencies on cardiac and peripheral vascular  -adrenoceptors of propranolol, of practolol and its ortho-substituted isomer, and of oxprenolol and its para-substituted isomer.
D000083:Acetanilides / Q000494:pharmacology; D000200:Action Potentials / Q000187:drug effects; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000605:Amino Alcohols / Q000494:pharmacology*; D000818:Animals; D001001:Anura; D001011:Aorta; D001775:Blood Circulation / Q000187:drug effects*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D006321:Heart / Q000187:drug effects; D006325:Heart Atria / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects*; D066298:In Vitro Techniques; D007269:Injections, Intra-Arterial; D007275:Injections, Intravenous; D007536:Isomerism; D007545:Isoproterenol / Q000008:administration & dosage / Q000037:antagonists & inhibitors; D008638:Mesenteric Arteries; D009928:Organ Specificity; D010096:Oxprenolol / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology*; D011817:Rabbits; D011941:Receptors, Adrenergic / Q000187:drug effects*; D012584:Sciatic Nerve / Q000502:physiology
D000083:Acetanilides; D000319:Adrenergic beta-Antagonists; D000605:Amino Alcohols; D011941:Receptors, Adrenergic; D010096:Oxprenolol; D011433:Propranolol; D007545:Isoproterenol