Serological distinction of mutants B6.CH(zl) and B6.M505 from strain C57BL-6.
A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2(b)). The finding suggests that the mutations occurred in the H-2K(b) gene, and together with data on MLR and CML challenges the current concept of H-2 regions' involvement in immune reactions.
D000818:Animals; D000918:Antibody Specificity; D003601:Cytotoxicity Tests, Immunologic; D000939:Epitopes; D005838:Genotype; D006386:Hemagglutination Tests; D006649:Histocompatibility Antigens; D007518:Isoantibodies / Q000032:analysis*; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D008810:Mice, Inbred C57BL; D009154:Mutation
D000939:Epitopes; D006649:Histocompatibility Antigens; D007518:Isoantibodies