Biophysical differentiation between lymphocytes from healthy donors, patients with malignant diseases and other disorders.
Changes in the structuredness of the cytoplasmic matrix (SCM) of human lymphocytes induced by PHA, CaBP and EF were studied with the technique of fluorescence polarization. The study suggests that the SCM test may offer a new and fast technique for the detection of malignant growth.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000951:Antigens, Neoplasm; D003593:Cytoplasm; D005260:Female; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology*; D008297:Male; D008722:Methods; D008875:Middle Aged; D004676:Myelin Basic Protein / Q000494:pharmacology; D009363:Neoplasm Proteins; D009369:Neoplasms / Q000175:diagnosis / Q000276:immunology*; D013050:Spectrometry, Fluorescence
D000951:Antigens, Neoplasm; D037102:Lectins; D004676:Myelin Basic Protein; D009363:Neoplasm Proteins