N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans.
D000818:Animals; D002248:Carbon Monoxide; D003622:Dapsone / Q000097:blood / Q000378:metabolism* / Q000652:urine; D004285:Dogs; D004912:Erythrocytes; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006900:Hydroxylation; D008297:Male; D008706:Methemoglobin; D008797:Metyrapone; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D009249:NADP; D010084:Oxidation-Reduction; D010100:Oxygen; D010634:Phenobarbital / Q000494:pharmacology; D011506:Proteins; D011817:Rabbits; D013997:Time Factors
D006454:Hemoglobins; D011506:Proteins; D009249:NADP; D002248:Carbon Monoxide; D003622:Dapsone; D008706:Methemoglobin; D010100:Oxygen; D010634:Phenobarbital; D008797:Metyrapone