Thyroxine deiodination associated with NADPH-dependent (enzymatic) and Fe3+-ADP-catalyzed (nonenzymatic) reactions in hepatic microsomes.
D000244:Adenosine Diphosphate; D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism; D002384:Catalysis; D066298:In Vitro Techniques; D007455:Iodine / Q000378:metabolism*; D007457:Iodine Radioisotopes; D007501:Iron; D007700:Kinetics; D050356:Lipid Metabolism; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D009249:NADP / Q000378:metabolism*; D010084:Oxidation-Reduction; D051381:Rats; D013974:Thyroxine / Q000378:metabolism*
D007457:Iodine Radioisotopes; D009249:NADP; D000244:Adenosine Diphosphate; D007455:Iodine; D007501:Iron; D001205:Ascorbic Acid; D013974:Thyroxine