title: Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
mesh_terms: D000693:Anaerobiosis; D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D002250:Carbon Radioisotopes; D002251:Carbon Tetrachloride / Q000378:metabolism / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005978:Glutathione / Q000494:pharmacology; D006221:Halothane / Q000378:metabolism*; D066298:In Vitro Techniques; D007668:Kidney / Q000166:cytology; D008168:Lung / Q000166:cytology; D008797:Metyrapone / Q000494:pharmacology; D008861:Microsomes / Q000378:metabolism; D008862:Microsomes, Liver / Q000032:analysis / Q000378:metabolism*; D009249:NADP; D010084:Oxidation-Reduction; D010100:Oxygen / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011485:Protein Binding / Q000187:drug effects; D011817:Rabbits; D013053:Spectrophotometry; D013447:Sulfites
chemical_list: D002250:Carbon Radioisotopes; D013447:Sulfites; D009249:NADP; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D011335:Proadifen; D002251:Carbon Tetrachloride; D005978:Glutathione; D010100:Oxygen; D006221:Halothane; D008797:Metyrapone