title: Isolation and characterization of the multiple forms of dihydrofolate reductase from methotrexate-resistant hamster cells.
mesh_terms: D000818:Animals; D002250:Carbon Radioisotopes; D002384:Catalysis; D002460:Cell Line; D002846:Chromatography, Affinity; D002850:Chromatography, Gel; D002918:Chymotrypsin; D006224:Cricetinae; D004351:Drug Resistance; D004357:Drug Synergism; D004591:Electrophoresis, Polyacrylamide Gel; D007525:Isoelectric Focusing; D007668:Kidney / Q000187:drug effects / Q000201:enzymology*; D046911:Macromolecular Substances; D009154:Mutation; D009249:NADP / Q000494:pharmacology; D010446:Peptide Fragments / Q000032:analysis; D011487:Protein Conformation; D013762:Tetrahydrofolate Dehydrogenase / Q000032:analysis / Q000302:isolation & purification* / Q000378:metabolism; D013937:Thymidine Kinase / Q000494:pharmacology; D014316:Tritium; D014357:Trypsin
chemical_list: D002250:Carbon Radioisotopes; D046911:Macromolecular Substances; D010446:Peptide Fragments; D014316:Tritium; D009249:NADP; D013762:Tetrahydrofolate Dehydrogenase; D013937:Thymidine Kinase; D002918:Chymotrypsin; D014357:Trypsin