The formation of "K-region" epoxides as hepatic microsomal metabolites of 7-methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and their 7-hydroxymethyl derivatives.
D000307:Adrenal Gland Diseases / Q000139:chemically induced; D000818:Animals; D001551:Benz(a)Anthracenes / Q000378:metabolism*; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D003460:Crystallization; D004988:Ethers, Cyclic / Q000096:biosynthesis*; D005978:Glutathione / Q000096:biosynthesis; D006150:Guanine Nucleotides / Q000378:metabolism; D006867:Hydrolases / Q000378:metabolism; D008297:Male; D000432:Methanol / Q000096:biosynthesis; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D009336:Necrosis / Q000139:chemically induced; D010636:Phenols / Q000378:metabolism; D051381:Rats; D014316:Tritium
D001551:Benz(a)Anthracenes; D004988:Ethers, Cyclic; D006150:Guanine Nucleotides; D010636:Phenols; D014316:Tritium; D008748:Methylcholanthrene; D009247:NADH, NADPH Oxidoreductases; D006867:Hydrolases; D005978:Glutathione; D000432:Methanol