title: Stereochemical studies on medicinal agents. 10. The role of chirality in alpha-adrenergic receptor blockage by (plus)-and(minus)-phenoxybenzamine hydrochloride.
mesh_terms: D000317:Adrenergic alpha-Antagonists; D000477:Alkylating Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D066298:In Vitro Techniques; D008297:Male; D008968:Molecular Conformation; D009119:Muscle Contraction / Q000187:drug effects; D009638:Norepinephrine / Q000037:antagonists & inhibitors; D010643:Phenoxybenzamine / Q000138:chemical synthesis* / Q000494:pharmacology; D011941:Receptors, Adrenergic / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013997:Time Factors; D014649:Vas Deferens / Q000187:drug effects
chemical_list: D000317:Adrenergic alpha-Antagonists; D000477:Alkylating Agents; D011941:Receptors, Adrenergic; D010643:Phenoxybenzamine; D009638:Norepinephrine