title: Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology.
abstract: Of 60 TRIC agents isolated from Gambian children with trachoma, 25 were serotype 1 and the remainder type 2. There was a pronounced difference in the proportions of these types in the two villages studied. In the village with a predominance of type 2 strains, TRIC agents remained confined to 2 adjacent compounds over a 14 month observation period. All 19 type 1 strains examined were characterized by the appearance in yolk sac smears of compact aggregates of elementary bodies; such aggregates were seen in only 2 of 35 type 2 strains, and may reflect a chemical difference in the surface of the elementary bodies or in a substance elaborated during their replication.
mesh_terms: D000818:Animals; D002642:Chick Embryo; D002648:Child; D002689:Chlamydia / Q000145:classification* / Q000166:cytology / Q000302:isolation & purification; D003235:Conjunctivitis, Inclusion / Q000209:etiology; D005455:Fluorescent Antibody Technique; D005714:Gambia; D006801:Humans; D007106:Immune Sera; D051379:Mice / Q000276:immunology; D008860:Microscopy, Ultraviolet; D010527:Perissodactyla / Q000276:immunology; D012703:Serotyping; D013194:Staining and Labeling; D014141:Trachoma / Q000209:etiology / Q000382:microbiology*; D014776:Virus Cultivation
chemical_list: D007106:Immune Sera