Hepatic synthesis of alpha 2 (acute phase)-globulin of rat plasma.
Synthesis of plasma alpha(2) (acute phase)-globulin was demonstrated in isolated perfused rat liver obtained from animals showing acute inflammatory reaction to injury. These findings indicate that the liver is a source of the globulin and that appearance of this protein in the serum results from de novo synthesis by the liver rather than from release of performed and stored globulin.
D000510:Alpha-Globulins / Q000096:biosynthesis*; D000818:Animals; D001769:Blood; D007122:Immunoelectrophoresis; D066298:In Vitro Techniques; D007249:Inflammation / Q000378:metabolism*; D007930:Leucine / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D011874:Radiometry; D051381:Rats; D014316:Tritium
D000510:Alpha-Globulins; D014316:Tritium; D007930:Leucine