Involvement of a hydrophobic site in the inhibition of the microsomal p-hydroxylation of aniline by alcohols.
D000433:1-Propanol / Q000494:pharmacology; D000438:Alcohols / Q000494:pharmacology*; D000632:Aminopyrine / Q000378:metabolism; D000814:Aniline Compounds / Q000378:metabolism*; D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D000440:Butanols / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003579:Cytochrome Reductases / Q000378:metabolism; D003640:Dealkylation; D003576:Electron Transport Complex IV / Q000378:metabolism; D000431:Ethanol / Q000494:pharmacology; D000441:Hexanols / Q000494:pharmacology; D006900:Hydroxylation; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008691:Methadone / Q000378:metabolism; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D009019:Morphinans / Q000378:metabolism; D009249:NADP; D009281:Naphthalenes; D000442:Octanols / Q000494:pharmacology; D051381:Rats; D013451:Sulfonic Acids
D000438:Alcohols; D000814:Aniline Compounds; D000440:Butanols; D000441:Hexanols; D009019:Morphinans; D009281:Naphthalenes; D000442:Octanols; D013451:Sulfonic Acids; D000632:Aminopyrine; D000431:Ethanol; D009249:NADP; D003577:Cytochrome P-450 Enzyme System; D000433:1-Propanol; D003579:Cytochrome Reductases; D003576:Electron Transport Complex IV; D008691:Methadone