Responses of the murine myeloid colony-forming cell to ansamycin antibiotics.
The in vitro susceptibility of murine myeloid colony-forming cells to the antiproliferative activities of three ansamycin antibiotics was determined. These cells were found to be 10- to 40-fold more susceptible than the corresponding human ones.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D002478:Cells, Cultured / Q000187:drug effects*; D006801:Humans; D051379:Mice; D008811:Mice, Inbred DBA; D009369:Neoplasms / Q000473:pathology*; D012294:Rifamycins / Q000494:pharmacology; D013310:Streptovaricin / Q000494:pharmacology
D000903:Antibiotics, Antineoplastic; D012294:Rifamycins; D013310:Streptovaricin