B-cell alloantigens determined by the H-2 linked Ir region are associated with mixed lymphocyte culture stimulation.
Cell surface antigens, controlled by genes located in the Ir region of the murine major histocompatibility complex, are shown serologically to be expressed preferentially on bone marrow-derived lymphocytes. These antigens may play a major role as stimulators in mixed lymphocyte cultures.
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D002874:Chromosome Mapping; D003434:Crossing Over, Genetic; D008040:Genetic Linkage; D006087:Graft vs Host Reaction; D006648:Histocompatibility; D006649:Histocompatibility Antigens; D007106:Immune Sera; D007519:Isoantigens; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D008815:Mice, Inbred Strains; D008954:Models, Biological; D011995:Recombination, Genetic; D016038:Skin Transplantation; D014184:Transplantation, Homologous
D006649:Histocompatibility Antigens; D007106:Immune Sera; D007519:Isoantigens