Conformationally restricted analogs of histamine H1 receptor antagonists. Trans- and cis-1,5-Diphenyl-3-dimethylaminopyrrolidine.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004123:Dimethylamines / Q000138:chemical synthesis / Q000494:pharmacology; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D006634:Histamine H1 Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D008968:Molecular Conformation; D009119:Muscle Contraction / Q000187:drug effects; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000494:pharmacology; D011955:Receptors, Drug; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013997:Time Factors; D014309:Tripelennamine / Q000494:pharmacology
D004123:Dimethylamines; D006634:Histamine H1 Antagonists; D011759:Pyrrolidines; D011955:Receptors, Drug; D014309:Tripelennamine; C007515:1,5-diphenyl-3-dimethylaminopyrrolidine; D006632:Histamine; D000109:Acetylcholine