title: Turnover of dihydrofolate reductase in rapidly dividing cells.
mesh_terms: D000818:Animals; D002247:Carbon Isotopes; D002455:Cell Division; D002477:Cells / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D002846:Chromatography, Affinity; D004352:Drug Resistance, Microbial; D006207:Half-Life; D007553:Isotope Labeling; D007700:Kinetics; D007780:Lacticaseibacillus casei / Q000201:enzymology / Q000378:metabolism; D007930:Leucine / Q000378:metabolism; D007939:Leukemia L1210 / Q000201:enzymology; D008727:Methotrexate; D051379:Mice; D009249:NADP / Q000378:metabolism; D011134:Polysaccharides; D013762:Tetrahydrofolate Dehydrogenase / Q000302:isolation & purification / Q000378:metabolism*; D013997:Time Factors
chemical_list: D002247:Carbon Isotopes; D011134:Polysaccharides; D009249:NADP; D013762:Tetrahydrofolate Dehydrogenase; D007930:Leucine; D008727:Methotrexate