Regulation of fatty acid synthesis in isolated hepatocytes. Evidence for a physiological role for long chain fatty acyl coenzyme A and citrate.
D001275:ATP Citrate (pro-S)-Lyase / Q000037:antagonists & inhibitors; D000085:Acetates / Q000378:metabolism; D000105:Acetyl Coenzyme A / Q000096:biosynthesis; D000103:Acetyl-CoA Carboxylase / Q000037:antagonists & inhibitors; D000818:Animals; D000831:Animals, Newborn; D002210:Caprylates / Q000378:metabolism; D002245:Carbon Dioxide / Q000378:metabolism; D002247:Carbon Isotopes; D002331:Carnitine / Q000494:pharmacology; D002645:Chickens; D002951:Citrates / Q000378:metabolism*; D003065:Coenzyme A / Q000378:metabolism*; D003066:Coenzyme A Ligases / Q000378:metabolism; D005227:Fatty Acids / Q000096:biosynthesis*; D005230:Fatty Acids, Nonesterified / Q000494:pharmacology; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D008862:Microsomes, Liver / Q000201:enzymology; D008930:Mitochondria, Liver / Q000201:enzymology; D013329:Structure-Activity Relationship; D013347:Subcellular Fractions / Q000201:enzymology; D014316:Tritium
D000085:Acetates; D002210:Caprylates; D002247:Carbon Isotopes; D002951:Citrates; D005227:Fatty Acids; D005230:Fatty Acids, Nonesterified; D014316:Tritium; D002245:Carbon Dioxide; D000105:Acetyl Coenzyme A; D001275:ATP Citrate (pro-S)-Lyase; D003066:Coenzyme A Ligases; D000103:Acetyl-CoA Carboxylase; D002331:Carnitine; D003065:Coenzyme A