Studies on receptor-mediated activation of adenylyl cyclases. IV. Characteristics of the adrenergic receptor coupled to myocardial adenylyl cyclase: stereospecificity for ligands and determination of apparent affinity constants for beta-blockers.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D002395:Catecholamines / Q000494:pharmacology*; D002415:Cats; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D002614:Chelating Agents / Q000494:pharmacology; D005260:Female; D006352:Heart Ventricles / Q000187:drug effects / Q000201:enzymology; D007536:Isomerism; D007545:Isoproterenol / Q000031:analogs & derivatives / Q000494:pharmacology; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D008297:Male; D008433:Mathematics; D009206:Myocardium / Q000201:enzymology*; D010761:Phosphorus Radioisotopes; D011956:Receptors, Cell Surface / Q000187:drug effects*; D012110:Reserpine / Q000494:pharmacology; D013015:Sotalol / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D002395:Catecholamines; D002614:Chelating Agents; D010761:Phosphorus Radioisotopes; D011956:Receptors, Cell Surface; D012110:Reserpine; D013015:Sotalol; D000262:Adenylyl Cyclases; D008274:Magnesium; D007545:Isoproterenol