Oxygenated norethindrone derivatives from incubation with beagle liver. Structure, synthesis, and biological activity.
D000818:Animals; D002250:Carbon Radioisotopes; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D002942:Circular Dichroism; D004285:Dogs; D004988:Ethers, Cyclic / Q000378:metabolism; D005260:Female; D005298:Fertility / Q000187:drug effects; D006900:Hydroxylation; D006914:Hydroxysteroids / Q000378:metabolism; D066298:In Vitro Techniques; D007659:Ketones / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D008862:Microsomes, Liver / Q000378:metabolism; D009640:Norethindrone / Q000378:metabolism* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D014599:Uterus / Q000187:drug effects
D002250:Carbon Radioisotopes; D004988:Ethers, Cyclic; D006914:Hydroxysteroids; D007659:Ketones; D009640:Norethindrone