Enzymatic oxidation of nicotine to nicotine   1'(5')  iminium ion. A newly discovered intermediate in the metabolism of nicotine.
D000818:Animals; D002248:Carbon Monoxide; D002849:Chromatography, Gas; D003486:Cyanides; D007097:Imines / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D013058:Mass Spectrometry; D008862:Microsomes, Liver / Q000378:metabolism; D009243:NAD; D009249:NADP; D009538:Nicotine / Q000378:metabolism*; D009570:Nitriles; D010084:Oxidation-Reduction; D010103:Oxygen Isotopes; D011817:Rabbits; D013055:Spectrophotometry, Infrared
D003486:Cyanides; D007097:Imines; D009570:Nitriles; D010103:Oxygen Isotopes; D009243:NAD; D009249:NADP; D009538:Nicotine; D002248:Carbon Monoxide