Possible mechanism for the fibrinolytic effect of certain bis-tetrahydroisquinolines: evidence for histamine release.
D000818:Animals; D001780:Blood Coagulation Tests; D001794:Blood Pressure / Q000187:drug effects; D004155:Diphenhydramine / Q000494:pharmacology; D004285:Dogs; D005342:Fibrinolysis / Q000187:drug effects; D005343:Fibrinolytic Agents / Q000494:pharmacology*; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D006636:Histamine Release / Q000187:drug effects*; D007546:Isoquinolines / Q000494:pharmacology*; D008738:Methyl Ethers / Q000494:pharmacology; D010640:Phenothiazines / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship
D005343:Fibrinolytic Agents; D006634:Histamine H1 Antagonists; D007546:Isoquinolines; D008738:Methyl Ethers; D010640:Phenothiazines; D004155:Diphenhydramine