Massive lethal hepatic necrosis in rats anesthetized with fluroxene, after microsomal enzyme induction.
D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D000818:Animals; D001835:Body Weight; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000473:pathology; D003577:Cytochrome P-450 Enzyme System / Q000032:analysis; D004790:Enzyme Induction; D004987:Ethers / Q000009:adverse effects*; D005260:Female; D006984:Hypertrophy / Q000139:chemically induced; D008099:Liver / Q000032:analysis / Q000187:drug effects / Q000473:pathology; D008862:Microsomes, Liver / Q000201:enzymology*; D009336:Necrosis / Q000139:chemically induced; D009929:Organ Size; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats
D004987:Ethers; D003577:Cytochrome P-450 Enzyme System; D010634:Phenobarbital