A theory of lymphocyte blast transformation (LBT) and malignant change based on proteolytic cleavage of trigger peptide: the detendomer.
D000595:Amino Acid Sequence; D000614:Aminocaproates / Q000494:pharmacology; D000906:Antibodies; D000936:Antigen-Antibody Complex; D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm; D000961:Antilymphocyte Serum / Q000494:pharmacology; D002462:Cell Membrane / Q000378:metabolism; D002471:Cell Transformation, Neoplastic; D002918:Chymotrypsin / Q000494:pharmacology; D003165:Complement System Proteins; D000939:Epitopes; D004950:Esterases / Q000378:metabolism; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D037102:Lectins / Q000494:pharmacology; D007956:Leukocidins / Q000494:pharmacology; D008213:Lymphocyte Activation; D010206:Papain / Q000494:pharmacology; D010455:Peptides / Q000378:metabolism*; D013210:Staphylococcus; D013301:Streptolysins / Q000494:pharmacology; D013601:T-Lymphocytes; D014118:Toxins, Biological / Q000494:pharmacology; D014357:Trypsin / Q000494:pharmacology
D000614:Aminocaproates; D000906:Antibodies; D000936:Antigen-Antibody Complex; D000951:Antigens, Neoplasm; D000961:Antilymphocyte Serum; D000939:Epitopes; D007074:Immunoglobulin G; D037102:Lectins; D007956:Leukocidins; D010455:Peptides; D013301:Streptolysins; D014118:Toxins, Biological; D003165:Complement System Proteins; D004950:Esterases; D002918:Chymotrypsin; D014357:Trypsin; D010206:Papain