title: Structure, function, and possible origin of a bifunctional allosteric enzyme, Escherichia coli aspartokinase I-homoserine dehydrogenase I.
mesh_terms: D000255:Adenosine Triphosphate / Q000031:analogs & derivatives; D000429:Alcohol Oxidoreductases / Q000276:immunology / Q000378:metabolism*; D000494:Allosteric Regulation; D000596:Amino Acids / Q000032:analysis; D000937:Antigen-Antibody Reactions; D001224:Aspartic Acid; D001665:Binding Sites; D004589:Electrophoresis, Disc; D004926:Escherichia coli / Q000201:enzymology*; D006714:Homoserine; D007700:Kinetics; D015122:Mercaptopurine; D008970:Molecular Weight; D009097:Multienzyme Complexes / Q000378:metabolism*; D009243:NAD; D009249:NADP; D010446:Peptide Fragments / Q000032:analysis; D010770:Phosphotransferases / Q000276:immunology / Q000378:metabolism*; D011485:Protein Binding; D011487:Protein Conformation; D012265:Ribonucleotides; D012694:Serine; D013053:Spectrophotometry; D013438:Sulfhydryl Compounds; D013912:Threonine
chemical_list: D000596:Amino Acids; D009097:Multienzyme Complexes; D010446:Peptide Fragments; D012265:Ribonucleotides; D013438:Sulfhydryl Compounds; D009243:NAD; D013912:Threonine; D001224:Aspartic Acid; D012694:Serine; D009249:NADP; D006714:Homoserine; D000255:Adenosine Triphosphate; D015122:Mercaptopurine; D000429:Alcohol Oxidoreductases; D010770:Phosphotransferases