title: The cyclic AMP system and drug development.
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D000067956:Adenylyl Cyclase Inhibitors; D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001921:Brain / Q000187:drug effects; D000242:Cyclic AMP / Q000031:analogs & derivatives / Q000378:metabolism*; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D000882:Haplorhini; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D008956:Models, Chemical; D010179:Pancreas / Q000187:drug effects; D010726:Phosphodiesterase Inhibitors; D011720:Pyrazoles / Q000494:pharmacology; D011725:Pyridines / Q000494:pharmacology; D051381:Rats; D013678:Technology, Pharmaceutical
chemical_list: D000067956:Adenylyl Cyclase Inhibitors; D014151:Anti-Anxiety Agents; D007328:Insulin; D010726:Phosphodiesterase Inhibitors; D011720:Pyrazoles; D011725:Pyridines; D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases