Recognition of streptococcal DNA by a mutant pneumococcus unable to discriminate among markers in pneumococcal DNA.
A mutant strain of pneumococcus which fails to discriminate against low-efficiency markers during transformation by homospecific pneumococcal donor DNA retains the wild-type capacity to discriminate against heterospecific (streptococcal) donor DNA. We conclude that discrimination against heterospecific DNA must differ from that against low-efficiency markers by the kind or number of elements being recognized.
D004269:DNA, Bacterial; D004917:Erythromycin / Q000494:pharmacology; D005672:Fusidic Acid / Q000494:pharmacology; D008034:Lincomycin / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009154:Mutation; D012293:Rifampin / Q000494:pharmacology; D013045:Species Specificity; D013291:Streptococcus / Q000187:drug effects; D013296:Streptococcus pneumoniae / Q000187:drug effects; D013307:Streptomycin / Q000494:pharmacology; D014170:Transformation, Genetic
D004269:DNA, Bacterial; D005672:Fusidic Acid; D004917:Erythromycin; D008034:Lincomycin; D012293:Rifampin; D013307:Streptomycin