title: Similar idiotypes in antibody-forming cells and in cells synthesizing immunoglobulins without detectable antibody function.
abstract: The occurrence of immunoglobulins with and without antibody specificity and with and without idiotypic specificity was studied, by use of enzyme-labeled antigen and antibodies, in lymph node cells of rabbits immunized with horse-radish peroxidase and hen ovalbumin. Some cells, containing immunoglobulins without detectable antibody function, were shown to contain idiotypes similar to those found in antibody-producing cells.
mesh_terms: D000469:Alkaline Phosphatase; D000818:Animals; D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic; D000918:Antibody Specificity; D000921:Antibody-Producing Cells / Q000276:immunology*; D000939:Epitopes; D007136:Immunoglobulins / Q000096:biosynthesis*; D008198:Lymph Nodes / Q000276:immunology; D010047:Ovalbumin / Q000276:immunology; D010544:Peroxidases / Q000276:immunology; D011817:Rabbits
chemical_list: D000906:Antibodies; D000888:Antibodies, Anti-Idiotypic; D000939:Epitopes; D007136:Immunoglobulins; D010047:Ovalbumin; D010544:Peroxidases; D000469:Alkaline Phosphatase