Cytochemical localization of lactate dehydrogenase in muscular dystrophy of the mouse.
By use of phenazine methosulfate and the "ncubation mixture film method," lactate dehydrogenase activity has been demonstrated in the dystrophic muscle fibers of strain 129 mice. The results indicate that for demonstration of lactate dehydrogenase activity in dystrophic muscle fibers phenazine methosulfate is necessary. This finding is typical for the "white" muscle fibers in the normal muscle and suggests that the dystrophy affects primarily the "white" muscle fibers.
D000818:Animals; D006651:Histocytochemistry; D066298:In Vitro Techniques; D007770:L-Lactate Dehydrogenase; D051379:Mice; D009132:Muscles / Q000201:enzymology*; D009136:Muscular Dystrophies / Q000378:metabolism*; D010619:Phenazines; D013194:Staining and Labeling
D010619:Phenazines; D007770:L-Lactate Dehydrogenase