Ectopic gonadotropin in a case of anaplastic large-cell carcinoma of the lung.
A case of ectopic gonadotropin production by a bronchogenic carcinoma is presented. Eleven similar cases have been previously reported. Urine gonadotropin titres appeared related to the size of the tumour mass since they decreased with response to treatment and increased when the tumour started progressing again. The hormone is most probably elaborated and secreted by the tumour cells.
D001344:Autopsy; D001761:Bleomycin / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology* / Q000532:radiotherapy; D006063:Chorionic Gonadotropin / Q000378:metabolism* / Q000652:urine; D003609:Dactinomycin / Q000627:therapeutic use; D006729:Hormones, Ectopic / Q000378:metabolism* / Q000652:urine; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology* / Q000532:radiotherapy; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D013736:Testicular Neoplasms; D014750:Vincristine / Q000627:therapeutic use
D006063:Chorionic Gonadotropin; D006729:Hormones, Ectopic; D001761:Bleomycin; D003609:Dactinomycin; D014750:Vincristine