Increased carbon tetrachloride hepatotoxicity, and its mechanism, after chronic ethanol consumption.
D000410:Alanine Transaminase / Q000378:metabolism; D000428:Alcohol Drinking; D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000818:Animals; D001663:Bilirubin / Q000097:blood; D001711:Biotransformation; D002245:Carbon Dioxide / Q000378:metabolism; D002250:Carbon Radioisotopes; D002251:Carbon Tetrachloride / Q000378:metabolism / Q000633:toxicity*; D002252:Carbon Tetrachloride Poisoning / Q000209:etiology; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D004357:Drug Synergism; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D066298:In Vitro Techniques; D008055:Lipids / Q000097:blood; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D009954:Ornithine Carbamoyltransferase / Q000378:metabolism; D011485:Protein Binding; D051381:Rats
D002250:Carbon Radioisotopes; D008055:Lipids; D002245:Carbon Dioxide; D000431:Ethanol; D009249:NADP; D003577:Cytochrome P-450 Enzyme System; D002251:Carbon Tetrachloride; D000633:Aminopyrine N-Demethylase; D009954:Ornithine Carbamoyltransferase; D000410:Alanine Transaminase; D005952:Glucose-6-Phosphatase; D001663:Bilirubin