Perinatal drug metabolism and morphological changes in the hepatocytes of normal and phenobarbital-treated guinea pigs.
D000375:Aging; D000814:Aniline Compounds / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D001580:Benzopyrenes / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003579:Cytochrome Reductases / Q000378:metabolism; D003640:Dealkylation; D005260:Female; D005333:Fetus; D005865:Gestational Age; D006168:Guinea Pigs; D006900:Hydroxylation; D008099:Liver / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology*; D010879:Piperazines / Q000378:metabolism; D049590:Postpartum Period; D011247:Pregnancy
D000814:Aniline Compounds; D001580:Benzopyrenes; D004364:Pharmaceutical Preparations; D010879:Piperazines; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D010089:Oxidoreductases, N-Demethylating; D003579:Cytochrome Reductases; D010634:Phenobarbital