[Evaluation of hepatic lesions in hyperthyroid conditions by means of determination of serum ornithine-carbamyl-transferase].
OCT is a high specific test of liver mythocondrial damage; it increases early in the serum, before any feature of cell necrosis can histologically demonstrated.  Serum values of this enzyme have been studied as an index of liver damage in 22 patients with hyperthyroidism lasting for a period of a minimum of two months to a maximum of two years.  Other serum enzymes (gamma-GT, pseudocolinesterase, transaminase) have been studied comparatively.  Serum OCT behaviour in the cases reported seems to suggest that hyperthyroidism can induce moderate liver functional improvement (not reliable to hemodynamic alterations) only after long time.
D000328:Adult; D000368:Aged; D004796:Clinical Enzyme Tests; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000175:diagnosis; D008107:Liver Diseases / Q000175:diagnosis* / Q000201:enzymology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009954:Ornithine Carbamoyltransferase / Q000097:blood*; D013960:Thyroid Function Tests; D000637:Transaminases / Q000097:blood; D005723:gamma-Glutamyltransferase / Q000097:blood
D009954:Ornithine Carbamoyltransferase; D005723:gamma-Glutamyltransferase; D000637:Transaminases
Valutazione di lesione epatica negli stati ipertiroidei per mezzo del dosaggio della ornitin-carbamil-transferasi sierica