A familial, balanced 2-5 translocation associated with trisomy 21 in one individual.
D000328:Adult; D002675:Child, Preschool; D002869:Chromosome Aberrations; D002900:Chromosomes, Human, 1-3; D002905:Chromosomes, Human, 4-5; D004314:Down Syndrome / Q000235:genetics*; D005260:Female; D006579:Heterozygote; D006801:Humans; D007621:Karyotyping; D008297:Male; D010375:Pedigree; D010641:Phenotype; D013194:Staining and Labeling