title: Antigenic determinants common to human immunoglobulins G and M: importance of conformational antigens.
abstract: Antiserums produced against certain isolated human myeloma IgGglobulins and absorbed in order to show only individual antigenic specificity crossreact with certain Waldenstrom IgM-globulins. Some of the common antigenic determinants revealed by these cross-reactions depend on the tertiary and quaternary structure of the IgG and IgM molecules and are independent of their K and L light-chain antigenic types.
mesh_terms: D000937:Antigen-Antibody Reactions; D006801:Humans; D007106:Immune Sera; D005779:Immunodiffusion; D005719:gamma-Globulins
chemical_list: D007106:Immune Sera; D005719:gamma-Globulins