title: The type-specific substance from Pneumococcus type 33B.
abstract: 1. The type-specific substance, S. 33B, from Pneumococcus type 33B contains P, 2.89; hexose, 51; total sugar, 69; galactosamine, 18; and d-glucose, 20%. 2. After degradation with alkali, followed by enzymic dephosphorylation, S. 33B yielded a hexasaccharide. 3. The hexasaccharide was assigned the structure O-beta-d-glucopyranosyl- (1-->5)-O-beta-d-galactofuranosyl- (1-->3)-O-2-acetamido-2-deoxy-beta-d- galactopyranosyl-(1-->4)-O-[alpha-d- galactopyranosyl-(1-->2)]-alpha-d-galactopyranosyl- (1-->2)-ribitol. 4. Phosphate residues in S. 33B are located on the hydroxyl groups at position 5 of ribitol units and on the hydroxyl groups at position 6 of hexopyranose residues.
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D002854:Chromatography, Paper; D005688:Galactosamine / Q000032:analysis; D005947:Glucose / Q000032:analysis; D006601:Hexoses / Q000032:analysis; D006868:Hydrolysis; D007106:Immune Sera; D005779:Immunodiffusion; D008745:Methylation; D011135:Polysaccharides, Bacterial / Q000032:analysis*; D012266:Ribose / Q000032:analysis; D013045:Species Specificity; D013296:Streptococcus pneumoniae / Q000032:analysis*; D013329:Structure-Activity Relationship; D013402:Sugar Alcohols / Q000032:analysis
chemical_list: D006601:Hexoses; D007106:Immune Sera; D011135:Polysaccharides, Bacterial; D013402:Sugar Alcohols; D012266:Ribose; D005688:Galactosamine; D005947:Glucose