Cytological detection of the c-25H deletion involving the albino (c) locus on chromosome 7 in the mouse.
A deletion of the albino (c) locus on mouse chromosome 7 has been demonstrated using Q- and G-banding methods in a mouse heterozygous for the radiation-induced lethal albino allele, c(25H). The deletion, which is thought to be 1-6 cM long, represents about 7.6% of the length of the metaphase chromosome.
D000417:Albinism / Q000235:genetics*; D000483:Alleles; D000818:Animals; D002455:Cell Division; D002842:Chromatids / Q000648:ultrastructure; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D002875:Chromosomes / Q000528:radiation effects / Q000648:ultrastructure*; D005260:Female; D005804:Genes, Lethal; D005816:Genetic Complementation Test; D006579:Heterozygote; D007621:Karyotyping; D008297:Male; D051379:Mice; D008806:Mice, Inbred AKR; D009154:Mutation; D011831:Radiation Genetics; D013194:Staining and Labeling