Antimetabolites of coenzyme Q. 20. Synthesis of new alkyl-5,8-quinoxalinequinones as potential inhibitors of coenzyme Q and as antimalarial drugs.
D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis* / Q000627:therapeutic use; D000963:Antimetabolites / Q000138:chemical synthesis* / Q000494:pharmacology; D002645:Chickens; D066298:In Vitro Techniques; D008288:Malaria / Q000188:drug therapy; D051379:Mice; D008928:Mitochondria / Q000201:enzymology; D009247:NADH, NADPH Oxidoreductases / Q000037:antagonists & inhibitors; D010962:Plasmodium berghei; D011809:Quinones / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D013385:Succinate Dehydrogenase / Q000037:antagonists & inhibitors; D014451:Ubiquinone / Q000037:antagonists & inhibitors*
D000962:Antimalarials; D000963:Antimetabolites; D011809:Quinones; D011810:Quinoxalines; D014451:Ubiquinone; D013385:Succinate Dehydrogenase; D009247:NADH, NADPH Oxidoreductases