title: Conformation effects on the activity of drugs. 4. Cyclic analogs of 1-(p-nitrophenyl)-2-isopropylaminoethanol. Synthesis and evaluation of the adrenergic beta-receptor blocking activity of 2-(p-nitrophenyl)-4-isopropylmorpholine.
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D003106:Colon / Q000187:drug effects; D004347:Drug Interactions; D004558:Electric Stimulation; D004837:Epinephrine / Q000494:pharmacology; D004983:Ethanolamines / Q000138:chemical synthesis* / Q000494:pharmacology; D005260:Female; D006325:Heart Atria / Q000187:drug effects; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology; D008297:Male; D008745:Methylation; D051379:Mice; D008968:Molecular Conformation; D009025:Morpholines / Q000138:chemical synthesis* / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects; D009578:Nitrobenzenes / Q000138:chemical synthesis / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D010627:Phenethylamines / Q000138:chemical synthesis* / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D013329:Structure-Activity Relationship
chemical_list: D000319:Adrenergic beta-Antagonists; D004983:Ethanolamines; D009025:Morpholines; D009578:Nitrobenzenes; D010627:Phenethylamines; C002797:2-(4-nitrophenyl)-4-isopropylmorpholine; D007545:Isoproterenol; D009638:Norepinephrine; D004837:Epinephrine