Lymphoid cells producing antibody against simple haptens: detection and enumeration.
Enumeration of cells producing antibody against arsanilic acid was made feasible by the use of hapten-conjugated sheep erythrocytes for the localized hemolysis-in-gel technique. The time of appearance and numbers of these hapten-specific plaque-forming cells correlated closely with the development of arsanilic acid-specific serum antibodies.
D000276:Adjuvants, Immunologic; D000818:Animals; D000917:Antibody Formation; D001151:Arsenic; D001798:Blood Proteins; D004912:Erythrocytes; D006168:Guinea Pigs; D006241:Haptens; D006433:Hemocyanins; D006461:Hemolysis; D066298:In Vitro Techniques; D008221:Lymphoid Tissue / Q000166:cytology*; D009169:Mycobacterium tuberculosis; D011817:Rabbits; D013154:Spleen / Q000166:cytology*; D005719:gamma-Globulins
D000276:Adjuvants, Immunologic; D001798:Blood Proteins; D006241:Haptens; D005719:gamma-Globulins; D006433:Hemocyanins; D001151:Arsenic