Inhibition of the catalytic site of adenylate cyclase in the central nervous system by phenothiazine derivatives.
D000067956:Adenylyl Cyclase Inhibitors; D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology*; D001665:Binding Sites / Q000187:drug effects; D002540:Cerebral Cortex / Q000166:cytology / Q000201:enzymology*; D000242:Cyclic AMP / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D007031:Hypothalamus / Q000166:cytology / Q000201:enzymology*; D066298:In Vitro Techniques; D008297:Male; D009457:Neuroglia / Q000187:drug effects / Q000201:enzymology; D009474:Neurons / Q000187:drug effects / Q000201:enzymology; D009638:Norepinephrine / Q000494:pharmacology; D010640:Phenothiazines / Q000494:pharmacology*; D011485:Protein Binding / Q000187:drug effects; D011817:Rabbits; D051381:Rats; D013329:Structure-Activity Relationship; D013997:Time Factors
D000067956:Adenylyl Cyclase Inhibitors; D014150:Antipsychotic Agents; D010640:Phenothiazines; D000242:Cyclic AMP; D009638:Norepinephrine