Carboxy-terminal amino acids of gamma-A and gamma-M heavy chains.
The carboxy-terminal amino acids of alpha-and micro-chains from human immunoglobulins and alpha-chains from mouse immunoglobulins have been determined by carboxypeptidase digestion and hydrazinolysis. The data suggest the following carboxy-terminal sequences: human micro: Ala-Gly-Thr-Cys-TyrCOOH; human alpha: Thr-Cys-TyrCOOH; murine alpha: (Ileu, Cys)-TyrCOOH.
D000595:Amino Acid Sequence; D000818:Animals; D002268:Carboxypeptidases; D002850:Chromatography, Gel; D006801:Humans; D006834:Hydrazines; D051379:Mice; D008967:Molecular Biology; D009101:Multiple Myeloma; D010455:Peptides / Q000032:analysis*; D010954:Plasmacytoma; D014443:Tyrosine / Q000032:analysis*; D008258:Waldenstrom Macroglobulinemia; D005719:gamma-Globulins / Q000032:analysis*
D006834:Hydrazines; D010455:Peptides; D005719:gamma-Globulins; D014443:Tyrosine; D002268:Carboxypeptidases