Histopathology of Listeria monocytogenes after oral feeding to mice.
Ingestion by mice of Listeria monocytogenes in drinking water induced micro-abscesses of the liver and ulcerative enteritis. In pregnant mice, these lesions were larger and more extensive than in nonpregnant female and male mice. Pregnancy is interrupted by a purulent panmetritis and necrotizing placentitis. The early microabscess is unique in that it consists of monocytic cells with bizarre-shaped nuclei. The experimentally induced pathological changes in livers and intestines of mice used in this study are similar to those observed in listeric neonatal septicemia of human infants.
D000818:Animals; D004032:Diet; D004064:Digestive System / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000473:pathology; D008089:Listeria monocytogenes / Q000302:isolation & purification; D008088:Listeriosis / Q000209:etiology / Q000473:pathology*; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D008297:Male; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000473:pathology*; D018805:Sepsis / Q000473:pathology; D013154:Spleen / Q000473:pathology; D013194:Staining and Labeling; D014599:Uterus / Q000473:pathology