[Use of methods for determination of nucleic acids in cancer cell cultures in experiments in vitro for selection of antineoplastic antibiotics and study of their mechanism of action].
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D002460:Cell Line / Q000187:drug effects; D046508:Culture Techniques; D004273:DNA, Neoplasm / Q000032:analysis*; D003609:Dactinomycin / Q000494:pharmacology; D003864:Depression, Chemical; D015643:Erythromycin Ethylsuccinate / Q000494:pharmacology; D007942:Leukemia, Experimental / Q000378:metabolism*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000378:metabolism; D051379:Mice; D009363:Neoplasm Proteins / Q000032:analysis*; D009848:Olivomycins / Q000494:pharmacology; D012334:RNA, Neoplasm / Q000032:analysis*; D013053:Spectrophotometry
D000903:Antibiotics, Antineoplastic; D004273:DNA, Neoplasm; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D015643:Erythromycin Ethylsuccinate; D003609:Dactinomycin; D009848:Olivomycins
Ispol'zovania metodov opredeleniia nukleinovykh kislot v kul'turakh rakovykh kletok v opytakh in vitro dliia otbora protivoopukholevykh antibiotikov i izucheniia mekhanizma ikh deĭstviia.