Heavy and light chain allotypic markers on rabbit homocytotropic antibody.
Evidence has been presented that rabbit homocytotropic antibody prepared against ovalbumin bears allotypic markers of both group a (heavy chain) and group b (light chain). This was shown by specific removal of activity in passive cutaneous anaphylaxis assays by anti-allotype immunoadsorbents. The homocytotropic antibody has properties which indicate that it belongs to a new class of rabbit immunoglobulin. These results demonstrate that this newly described class possesses the allotypes of both groups a and b, as has been previously shown for other rabbit immunoglobulin classes.
D000276:Adjuvants, Immunologic; D000327:Adsorption; D000818:Animals; D000906:Antibodies; D055598:Chemical Phenomena; D002621:Chemistry; D007114:Immunization; D010047:Ovalbumin; D010323:Passive Cutaneous Anaphylaxis; D011817:Rabbits; D005719:gamma-Globulins / Q000145:classification
D000276:Adjuvants, Immunologic; D000906:Antibodies; D005719:gamma-Globulins; D010047:Ovalbumin