Changes resembling lupus erythematosus after prolonged treatment with Ro-4-4602, a potent inhibitor of 5-HTP-carboxyliase, in white rats.
D006916:5-Hydroxytryptophan / Q000037:antagonists & inhibitors*; D062365:Aminobenzoates / Q000378:metabolism; D000818:Animals; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors*; D002784:Cholesterol / Q000097:blood; D003404:Creatinine / Q000097:blood; D005260:Female; D006834:Hydrazines / Q000009:adverse effects* / Q000633:toxicity; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D007668:Kidney / Q000032:analysis / Q000473:pathology; D007737:Kynurenine / Q000032:analysis; D008099:Liver / Q000032:analysis / Q000201:enzymology / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008297:Male; D009504:Neutrophils; D011392:Proline / Q000032:analysis; D051381:Rats; D013154:Spleen / Q000032:analysis / Q000473:pathology; D014364:Tryptophan / Q000032:analysis / Q000652:urine; D014642:Vanilmandelic Acid / Q000378:metabolism
D062365:Aminobenzoates; D006834:Hydrazines; D007737:Kynurenine; D006897:Hydroxyindoleacetic Acid; D014642:Vanilmandelic Acid; D014364:Tryptophan; D002784:Cholesterol; D011392:Proline; D003404:Creatinine; D006916:5-Hydroxytryptophan; D002262:Carboxy-Lyases