Antibiotic sensitivity of Micrococcus radiodurans.
A wild-type strain of Micrococcus radiodurans and its nonpigmented mutant W(1) were tested for sensitivity to 10 antibiotics selected from the standpoint of their mechanism of action. Representatives of groups of antibiotics inhibiting deoxyribonucleic acid (DNA) synthesis, DNA-dependent ribonucleic acid synthesis, protein synthesis, and cell wall synthesis were selected. M. radiodurans and its mutant exhibited full susceptibility to all antibiotics tested (mitomycin C, actinomycin D, chloramphenicol, dihydrostreptomycin, erythromycin, neomycin, kanamycin, benzylpenicillin, bacitracin, and vancomycin), the degree of susceptibility being of the same order as that of a standard strain of Staphylococcus aureus 209 P, with the exception of dihydrostreptomycin.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001414:Bacitracin / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D003609:Dactinomycin / Q000494:pharmacology; D004096:Dihydrostreptomycin Sulfate / Q000494:pharmacology; D004917:Erythromycin / Q000494:pharmacology; D007612:Kanamycin / Q000494:pharmacology; D008837:Micrococcus / Q000187:drug effects*; D008937:Mitomycins / Q000494:pharmacology; D009355:Neomycin / Q000494:pharmacology; D010400:Penicillin G / Q000494:pharmacology; D010403:Penicillin Resistance; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D008937:Mitomycins; D001414:Bacitracin; D003609:Dactinomycin; D007612:Kanamycin; D004917:Erythromycin; D002701:Chloramphenicol; D014640:Vancomycin; D009355:Neomycin; D010400:Penicillin G; D004096:Dihydrostreptomycin Sulfate