Myocardial necrosis and mineralization in normal and Aleutian disease mink fed dexamethasone.
Focal myocardial necrosis with mineralization occurred in mink fed the synthetic corticosteroid, dexamethasone, as a treatment for aleutian disease. Cardiac lesions occurred with equal frequency in steroid-fed controls and appeared to be related only to feeding of dexamethasone. Possible pathogenetic mechanisms are considered.
D000820:Animal Diseases; D000818:Animals; D001796:Blood Protein Disorders / Q000188:drug therapy / Q000662:veterinary*; D002114:Calcinosis / Q000139:chemically induced* / Q000473:pathology; D009202:Cardiomyopathies / Q000139:chemically induced* / Q000473:pathology; D003907:Dexamethasone / Q000009:adverse effects*; D008907:Mink; D009336:Necrosis; D014777:Virus Diseases / Q000188:drug therapy / Q000662:veterinary*; D005719:gamma-Globulins
D005719:gamma-Globulins; D003907:Dexamethasone