The frequency of conditions due to mutant genes of large effect.
D000293:Adolescent; D000328:Adult; D002648:Child; D002869:Chromosome Aberrations; D003241:Consanguinity; D005260:Female; D005799:Genes, Dominant; D005808:Genes, Recessive; D030342:Genetic Diseases, Inborn; D005838:Genotype; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009154:Mutation