Lindane: metabolism to a new isomer of pentachlorocyclohexene.
Two of the hexane-soluble products of metabolism of lindane in susceptible and resistant houseflies were tentatively identified as isomers of pentachlorocyclohexene by gas-liquid chromatography and mass spectroscopy. One isomer was identical with the pentachlorocyclohexene obtained by mild alkaline dehydrochlorination of lindane and is apparently the form found in previous studies of metabolism; the second is now reported for the first time.
D000818:Animals; D001711:Biotransformation; D002849:Chromatography, Gas; D003516:Cycloparaffins / Q000032:analysis / Q000378:metabolism*; D001556:Hexachlorocyclohexane / Q000378:metabolism*; D006793:Houseflies; D006846:Hydrocarbons, Halogenated / Q000032:analysis / Q000378:metabolism*; D007305:Insecticide Resistance; D013057:Spectrum Analysis; D013237:Stereoisomerism
D003516:Cycloparaffins; D006846:Hydrocarbons, Halogenated; D001556:Hexachlorocyclohexane