Antigen receptor molecules: inhibition by antiserum against kappa light chains.
Rabbit antiserum against mouse kappa chains, the predominant class of light chains found in mouse immunoglobulins, inhibits the immune response in vitro of mouse spleen cells to erythrocyte antigens. The inhibition becomes irreversible if the mouse spleen cells are treated briefly with both antiserum to kappa chains and complement.
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D000921:Antibody-Producing Cells; D000941:Antigens; D001769:Blood; D003165:Complement System Proteins; D003864:Depression, Chemical; D004912:Erythrocytes / Q000276:immunology*; D006462:Hemolytic Plaque Technique; D007106:Immune Sera / Q000494:pharmacology*; D007136:Immunoglobulins; D066298:In Vitro Techniques; D051379:Mice; D010455:Peptides; D011817:Rabbits; D012756:Sheep; D013154:Spleen / Q000166:cytology / Q000276:immunology*; D005719:gamma-Globulins
D000941:Antigens; D007106:Immune Sera; D007136:Immunoglobulins; D010455:Peptides; D005719:gamma-Globulins; D003165:Complement System Proteins