Structure-activity relationships in narcotic antagonists with N-furylmethyl substituents.
D000215:Acylation; D000478:Alkylation; D000700:Analgesics / Q000494:pharmacology; D000818:Animals; D005260:Female; D005663:Furans / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity; D000882:Haplorhini; D006801:Humans; D007536:Isomerism; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008968:Molecular Conformation; D009019:Morphinans / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity; D009020:Morphine / Q000037:antagonists & inhibitors; D009292:Narcotic Antagonists / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity; D013329:Structure-Activity Relationship; D019966:Substance-Related Disorders; D013623:Tail / Q000187:drug effects
D000700:Analgesics; D005663:Furans; D009019:Morphinans; D009292:Narcotic Antagonists; D009020:Morphine