The role of surgery and hyperalimentation in therapy of gastrointestinal-cutaneous fistulae.
Thirty-eight patients with external gastrointestinal fistulas arising from different levels of the gastrointestinal tract, observed and treated at the Massachusetts General Hospital, from December 1970 to April 1973, are analyzed. Surgical complications were the causes of fistulization in 77% of the cases. The treatment program included parenteral nutrition through a subclavian line in all cases. The 38 patients were fed parenterally for a total of 2311 days. Spontaneous fistula closure occurred in only 11 of the 38 patients. Surgical procedures were necessary in 71.05% of the cases to control fistula complications or persistent fistula drainage. Operative success rate was 70.4%. Parenteral nutrition effects on metabolic parameters, fistula secretion, nutritional status, morbidity and mortality of fistulas are discussed. Parenteral nutrition hazards are also presented. Overall mortality in this series was 21%. Roles of parenteral nutrition and surgery in the total management of external gastrointestinal fistulas are suggested.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005402:Fistula / Q000378:metabolism / Q000401:mortality / Q000601:surgery / Q000628:therapy; D005747:Gastric Fistula / Q000378:metabolism / Q000401:mortality / Q000601:surgery / Q000628:therapy; D006801:Humans; D007412:Intestinal Fistula / Q000378:metabolism / Q000401:mortality / Q000601:surgery / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009748:Nutrition Disorders / Q000628:therapy; D010288:Parenteral Nutrition / Q000009:adverse effects; D011183:Postoperative Complications; D018805:Sepsis / Q000209:etiology; D012871:Skin Diseases / Q000378:metabolism / Q000401:mortality / Q000601:surgery / Q000628:therapy; D014882:Water-Electrolyte Balance