Selective phosphorylation of the 5''-hydroxy group of ribostamycin by a new enzyme from Pseudomonas aeruginosa.
It was found that the 5''-hydroxy group of ribostamycin was preferentially phosphorylated by a cell-free extract from Pseudomonas aeruginosa GN 573, a clinical isolate.
D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D002474:Cell-Free System; D002855:Chromatography, Thin Layer; D010085:Oxidative Phosphorylation; D011550:Pseudomonas aeruginosa / Q000201:enzymology*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents