Isolation of Rickettsia rickettsi in primary bone marrow cell and circulating monocyte cultures derived from experimentally infected guinea pigs.
Rickettsia rickettsi was isolated and propagated in primary cell cultures derived from experimentally infected guinea pigs. Organisms were recognized as early as 3 days after cultures were initiated.
D000818:Animals; D001853:Bone Marrow / Q000382:microbiology*; D001854:Bone Marrow Cells; D002478:Cells, Cultured; D006168:Guinea Pigs; D009000:Monocytes / Q000382:microbiology*; D012282:Rickettsia Infections / Q000382:microbiology; D012284:Rickettsia rickettsii / Q000302:isolation & purification*