[Atrio-ventricular block in rheumatoid polyarthritis. Histological study of the His-Tawara system. Apropos of 2 cases].
A histological study of the conduction pathways was performed by serial sections in two patients who died with atrio-ventricular block in the course of rhumatoid arthritis. In the first case, the conduction disturbance was preceded by attacks of supra-ventricular paroxysmal tachycardia. The His-Tawara system was wholly infiltrated by a cast of lympho-plamocytes starting from rhumatoid nodules located at the base of both mitral and tricuspid valves and at the root of the aorta. The sinus node was the seat of a common fibrosis. In the second case, the atrio-ventricular block was secondary to amylosis which predominated in the central fibrous node and in the adjacent small coronary vessels. The His-Tawara system was completely destroyed down to its bifurcation. The sinus node was normal.
D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000473:pathology; D001172:Arthritis, Rheumatoid / Q000150:complications*; D001344:Autopsy; D002036:Bundle of His / Q000473:pathology; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000209:etiology* / Q000473:pathology; D006329:Heart Conduction System / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012218:Rheumatoid Nodule; D012849:Sinoatrial Node / Q000473:pathology
Le bloc auriculo-ventriculaire de la polyarthrite rhumatoïde Etude histologiquie du systéme de His-Tawara. A propos de deux observations