Osteoporosis and long-term corticosteroid therapy.
Sequential measurements of total body calcium by in-vivo neutron activation analysis were made in five patients treated with corticosteroid drugs for severe inflammatory disease. No evidence of osteoporosis was seen to develop during the course of 20-33 months of study. In one case a substantial rise in total body calcium was found.
D000201:Activation Analysis; D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use*; D000328:Adult; D001823:Body Composition; D002118:Calcium / Q000032:analysis*; D002127:Calcium Isotopes; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009502:Neutrons; D010024:Osteoporosis / Q000139:chemically induced / Q000209:etiology*; D011241:Prednisone / Q000627:therapeutic use; D014915:Whole-Body Counting
D000305:Adrenal Cortex Hormones; D002127:Calcium Isotopes; D002118:Calcium; D011241:Prednisone