Ecological application of antibiotics as respiratory inhibitors of bacterial populations.
Two terregenous and four marine bacterial isolates were treated with six antibiotics and antibiotic combinations. Comparisons made between responses of cells in early and late logarithmic and stationary growth phases indicated variable sensitivity to the agents. Bacteria in stationary and late log-phase cultures exhibited the greatest resistance, whereas the early log-phase cells exhibited greatest antibiotic susceptibility. We conclude that the tested antibiotics cannot be used for ecological purposes to delineate bacterial respiration in mixed microbial communities.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects / Q000378:metabolism*; D002455:Cell Division; D002701:Chloramphenicol / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D009355:Neomycin / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects*; D010400:Penicillin G / Q000494:pharmacology; D010403:Penicillin Resistance; D011549:Pseudomonas / Q000187:drug effects / Q000378:metabolism*; D012623:Seawater; D013307:Streptomycin / Q000494:pharmacology; D014733:Vibrio / Q000187:drug effects / Q000378:metabolism*; D014871:Water Microbiology
D000900:Anti-Bacterial Agents; D002701:Chloramphenicol; D009355:Neomycin; D010400:Penicillin G; D013307:Streptomycin