Inhibition of Streptomyces griseus protease B by peptide chloromethyl ketones: partial mapping of the binding site and identification of the reactive residue.
D000596:Amino Acids / Q000032:analysis; D001665:Binding Sites; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D003488:Cyanogen Bromide; D006863:Hydrogen-Ion Concentration; D007659:Ketones / Q000494:pharmacology*; D007700:Kinetics; D009842:Oligopeptides / Q000494:pharmacology*; D011480:Protease Inhibitors; D011485:Protein Binding; D013056:Spectrophotometry, Ultraviolet; D013305:Streptomyces griseus / Q000187:drug effects / Q000201:enzymology*; D013329:Structure-Activity Relationship; D013997:Time Factors; D014105:Tosyl Compounds
D000596:Amino Acids; D007659:Ketones; D009842:Oligopeptides; D011480:Protease Inhibitors; D014105:Tosyl Compounds; D003488:Cyanogen Bromide