Assessment of the agonist and antagonist properties of narcotic analgesic drugs by their actions on the morphine receptor in the guinea pig ileum.
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D001667:Binding, Competitive; D001681:Biological Assay; D055598:Chemical Phenomena; D002621:Chemistry; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D006168:Guinea Pigs; D006207:Half-Life; D000882:Haplorhini; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D009019:Morphinans / Q000494:pharmacology; D009020:Morphine / Q000037:antagonists & inhibitors* / Q000378:metabolism; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D009269:Nalorphine / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000378:metabolism / Q000494:pharmacology*; D011955:Receptors, Drug / Q000187:drug effects*; D013045:Species Specificity; D013618:Tachyphylaxis / Q000187:drug effects; D013997:Time Factors
D000700:Analgesics; D009019:Morphinans; D009292:Narcotic Antagonists; D011955:Receptors, Drug; D009270:Naloxone; D009020:Morphine; D009269:Nalorphine