Comparison of strains of BCG. I. Antigenic analysis and tuberculin reactivity.
At least 10 of 11 demonstrable antigens in unheated culture filtrates of 12 vaccine strains of BCG were shared as determined in a reference antigen-antibody immunoelectrophoresis system. Filtrates from each of the BCG strains gave equivalent skin test reactions in homologously and heterologously sensitized guinea pigs. By these immunological parameters, the 12 BCG strains were remarkably similar.
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis*; D005260:Female; D006168:Guinea Pigs; D007106:Immune Sera / Q000592:standards; D007122:Immunoelectrophoresis; D009169:Mycobacterium tuberculosis / Q000145:classification*; D013045:Species Specificity; D014374:Tuberculin Test
D000942:Antigens, Bacterial; D007106:Immune Sera