The ovicidal effect of selected chemicals against eggs of Echinococcus granulosus.
The ovicidal activity of various chemicals against eggs of E. granulosus was evaluated by measuring infectivity to CF(1) mice after exposing the eggs to aqueous solutions of the chemicals for 1 h at room temperature. Significant reductions in infectivity were observed in eggs treated with Lugol's iodine, 0.015% ammonium dodecylbenzenesulfonate, 70% ethanol, or 5% or 10% glutaraldehyde. No cysts developed in 10 mice that received doses of 1 000 eggs treated with 5% glutaraldehyde, and only 1 of 10 mice developed cysts after exposure to eggs treated with 10% glutaraldehyde.
D000818:Animals; D001557:Benzenesulfonates / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D004446:Echinococcus / Q000472:pathogenicity*; D000431:Ethanol / Q000494:pharmacology; D005260:Female; D005557:Formaldehyde / Q000494:pharmacology; D005976:Glutaral / Q000494:pharmacology; D007455:Iodine / Q000494:pharmacology; D051379:Mice; D010063:Ovum / Q000187:drug effects*; D011136:Polysorbates / Q000494:pharmacology; D011196:Potassium Permanganate / Q000494:pharmacology; D012973:Sodium Hypochlorite / Q000494:pharmacology
D001557:Benzenesulfonates; D004202:Disinfectants; D011136:Polysorbates; D011196:Potassium Permanganate; D005557:Formaldehyde; D000431:Ethanol; D007455:Iodine; D012973:Sodium Hypochlorite; D005976:Glutaral