The production of high potency diphtheria toxin in submerged culture in relatively simple equipment using a semisynthetic medium.
D000818:Animals; D001431:Bacteriological Techniques / Q000295:instrumentation; D002118:Calcium / Q000494:pharmacology; D002364:Caseins; D002417:Cattle; D003353:Corynebacterium diphtheriae / Q000254:growth & development / Q000378:metabolism*; D003470:Culture Media; D004167:Diphtheria Toxin / Q000032:analysis / Q000096:biosynthesis*; D005285:Fermentation; D005779:Immunodiffusion; D007501:Iron / Q000494:pharmacology; D008460:Meat; D010710:Phosphates / Q000494:pharmacology; D011492:Protein Hydrolysates
D002364:Caseins; D003470:Culture Media; D004167:Diphtheria Toxin; D010710:Phosphates; D011492:Protein Hydrolysates; D007501:Iron; D002118:Calcium