A functional abnormality of the fifth component of complement (C5) from human serum of individuals with a familial opsonic defect.
D000818:Animals; D000936:Antigen-Antibody Complex; D000941:Antigens; D002499:Centrifugation, Density Gradient; D002633:Chemotaxis; D003165:Complement System Proteins / Q000302:isolation & purification*; D004591:Electrophoresis, Polyacrylamide Gel; D004912:Erythrocytes / Q000187:drug effects / Q000276:immunology; D005978:Glutathione / Q000494:pharmacology; D006386:Hemagglutination Tests; D006461:Hemolysis; D006801:Humans; D007106:Immune Sera; D005779:Immunodiffusion; D007153:Immunologic Deficiency Syndromes / Q000276:immunology*; D051379:Mice / Q000276:immunology; D009895:Opsonin Proteins; D010587:Phagocytosis; D011817:Rabbits / Q000276:immunology; D012756:Sheep / Q000276:immunology; D014461:Ultracentrifugation; D015003:Yeasts
D000936:Antigen-Antibody Complex; D000941:Antigens; D007106:Immune Sera; D009895:Opsonin Proteins; D003165:Complement System Proteins; D005978:Glutathione