Immunological studies on the envelope component of Venezuelan equine encephalomyelitis virus.
Treatment of purified Venezuelan equine encephalomyelitis virus with the nonionic detergent Triton X-100 permitted spearation of the envelope from the core component. The isolated envelope was a noninfectious immunogen which reacted in hemagglutination, hemagglutination inhibition, complement fixation, and neutralization serological reactions.
D000596:Amino Acids; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis / Q000302:isolation & purification*; D002460:Cell Line; D002642:Chick Embryo; D003168:Complement Fixation Tests; D006224:Cricetinae; D046508:Culture Techniques; D004591:Electrophoresis, Polyacrylamide Gel; D004666:Encephalitis Virus, Venezuelan Equine / Q000276:immunology*; D004683:Encephalomyelitis, Equine / Q000517:prevention & control; D005944:Glucosamine; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D007106:Immune Sera; D005779:Immunodiffusion; D007668:Kidney; D051379:Mice; D008854:Microscopy, Electron; D009500:Neutralization Tests; D013501:Surface-Active Agents; D014316:Tritium; D014461:Ultracentrifugation; D014776:Virus Cultivation
D000596:Amino Acids; D000956:Antigens, Viral; D007106:Immune Sera; D013501:Surface-Active Agents; D014316:Tritium; D005944:Glucosamine