Stereotactic amygdaloidotomy for aggressive behaviour.
Amygdaloidotomy was performed bilaterally on 15 and unilaterally on three patients exhibiting severe aggressive or self-mutilating behaviour. Nine subjects (50%) were improved a year after operation; improvement was maintained in seven (39%) for periods ranging from 27 months to nearly six years. Four non-epileptic cases had convulsions during the period of review; one of them has a persistent mild hemiparesis dating from the postoperative period. There was a tendency for epileptics to respond better than non-epileptics and for mentally retarded patients to respond poorly, but none of the differences was statistically significant.
D000293:Adolescent; D000328:Adult; D000374:Aggression; D000679:Amygdala / Q000601:surgery*; D004832:Epilepsy, Absence / Q000150:complications; D004833:Epilepsy, Temporal Lobe / Q000150:complications; D004830:Epilepsy, Tonic-Clonic / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000601:surgery; D008297:Male; D010554:Personality Disorders / Q000150:complications / Q000601:surgery; D011612:Psychosurgery / Q000009:adverse effects; D012559:Schizophrenia / Q000150:complications / Q000601:surgery; D012640:Seizures / Q000209:etiology; D012652:Self Mutilation / Q000601:surgery*; D013238:Stereotaxic Techniques