Inhibition of mammalian dihydrofolate reductase by selected 2,4-diaminiquinazolines and related compounds.
D000818:Animals; D014355:Chagas Disease / Q000188:drug therapy; D003959:Diamines / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D013293:Enterococcus faecalis / Q000187:drug effects / Q000201:enzymology; D005493:Folic Acid Antagonists; D066298:In Vitro Techniques; D007939:Leukemia L1210 / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008288:Malaria / Q000188:drug therapy; D051379:Mice; D010962:Plasmodium berghei; D011799:Quinazolines / Q000138:chemical synthesis / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D014349:Trypanosoma cruzi
D003959:Diamines; D005493:Folic Acid Antagonists; D011799:Quinazolines