Morphological alterations of Pseudomonas aeruginosa by ticarcillin: a scanning electron microscope study.
Pseudomonas aeruginosa was exposed to 0.1, 1.0, 10, 100, and 1,000 times the minimal inhibitory concentration of ticarcillin in vitro and subsequently examined with the scanning electron microscope. The morphological alterations observed were filamentation, mid-cell defects, and spheroplast formation, and these alterations were dependent upon the drug concentration.
D002264:Carboxylic Acids / Q000494:pharmacology; D003470:Culture Media; D008855:Microscopy, Electron, Scanning; D010406:Penicillins / Q000031:analogs & derivatives*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000648:ultrastructure*; D013876:Thiophenes / Q000494:pharmacology
D002264:Carboxylic Acids; D003470:Culture Media; D010406:Penicillins; D013876:Thiophenes