Biological significance of serum albumin binding parameters determined in vitro for clofibrate-related hypolipemic drugs: use of 2-(4'-hydroxybenzeneazo)benzoic acid to mirror L-thyroxine binding to and displacement from serum albumins.
D000818:Animals; D001391:Azo Compounds; D001565:Benzoates; D001667:Binding, Competitive; D002264:Carboxylic Acids; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D002994:Clofibrate / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D007202:Indicators and Reagents; D008722:Methods; D010636:Phenols; D011485:Protein Binding; D051381:Rats; D012044:Regression Analysis; D012709:Serum Albumin / Q000378:metabolism*; D012710:Serum Albumin, Bovine / Q000378:metabolism; D012711:Serum Albumin, Radio-Iodinated / Q000378:metabolism; D013975:Thyroxine-Binding Proteins / Q000378:metabolism*
D001391:Azo Compounds; D001565:Benzoates; D002264:Carboxylic Acids; D007202:Indicators and Reagents; D010636:Phenols; D012709:Serum Albumin; D012711:Serum Albumin, Radio-Iodinated; D013975:Thyroxine-Binding Proteins; D012710:Serum Albumin, Bovine; D002994:Clofibrate