The blockade of the local generation of prostaglandins explains the analgesic action of aspirin.
D000818:Animals; D001241:Aspirin / Q000494:pharmacology*; D001920:Bradykinin / Q000494:pharmacology; D004357:Drug Synergism; D007213:Indomethacin / Q000494:pharmacology; D010146:Pain; D011448:Prostaglandin Antagonists; D011453:Prostaglandins / Q000096:biosynthesis*
D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D001241:Aspirin; D001920:Bradykinin; D007213:Indomethacin