CCNU (NSC-79037): preclinical toxicologic evaluation of a single intravenous infusion in dogs and monkeys.
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000633:toxicity*; D001853:Bone Marrow / Q000187:drug effects; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D003510:Cyclohexanes / Q000008:administration & dosage / Q000633:toxicity; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D000882:Haplorhini; D006456:Hemoglobinuria / Q000139:chemically induced; D007275:Injections, Intravenous; D007422:Intestines / Q000187:drug effects; D007668:Kidney / Q000187:drug effects; D007970:Leukopenia / Q000139:chemically induced; D008099:Liver / Q000187:drug effects; D008221:Lymphoid Tissue / Q000187:drug effects; D008251:Macaca; D008297:Male; D009393:Nephritis / Q000139:chemically induced; D009504:Neutrophils / Q000187:drug effects; D009607:Nitrosourea Compounds / Q000008:administration & dosage / Q000633:toxicity*; D013045:Species Specificity; D013737:Testis / Q000187:drug effects; D013997:Time Factors; D014511:Uremia / Q000139:chemically induced
D000970:Antineoplastic Agents; D003510:Cyclohexanes; D009607:Nitrosourea Compounds; D000410:Alanine Transaminase