Methotrexate analogs. 4.7-Methyl derivatives of methotrexate and dichloromethotrexate. A new synthesis and some biological studies.
D000818:Animals; D002460:Cell Line; D002713:Chlorine / Q000494:pharmacology / Q000627:therapeutic use; D013293:Enterococcus faecalis / Q000187:drug effects; D005493:Folic Acid Antagonists; D006801:Humans; D007780:Lacticaseibacillus casei / Q000201:enzymology; D007939:Leukemia L1210 / Q000188:drug therapy / Q000201:enzymology; D007942:Leukemia, Experimental / Q000378:metabolism; D007945:Leukemia, Lymphoid; D009682:Magnetic Resonance Spectroscopy; D008697:Methane / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D008727:Methotrexate / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D051379:Mice; D013056:Spectrophotometry, Ultraviolet
D005493:Folic Acid Antagonists; D002713:Chlorine; D008697:Methane; D008727:Methotrexate