If your patient can't tolerate the cold--suspect cryoglobulinemia.
D000169:Acrodermatitis / Q000097:blood; D000220:Adaptation, Biological; D000743:Anemia, Hemolytic / Q000097:blood; D000818:Animals; D011232:Chemical Precipitation; D003080:Cold Temperature; D003450:Cryoglobulins; D003937:Diagnosis, Differential; D004590:Electrophoresis, Paper; D006801:Humans; D007070:Immunoglobulin A; D007128:Immunoglobulin Fragments; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007945:Leukemia, Lymphoid / Q000097:blood; D008223:Lymphoma / Q000097:blood; D008297:Male; D008654:Mesothelioma / Q000097:blood; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood; D009194:Myeloma Proteins; D011164:Porphyrias / Q000097:blood; D011928:Raynaud Disease / Q000175:diagnosis*; D013577:Syndrome; D013696:Temperature; D013997:Time Factors; D008258:Waldenstrom Macroglobulinemia / Q000097:blood; D014973:Xanthomatosis / Q000097:blood
D003450:Cryoglobulins; D007070:Immunoglobulin A; D007128:Immunoglobulin Fragments; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D009194:Myeloma Proteins