The carboxypeptidase-dependent inactivation of thymidylate synthetase.
D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001593:Benzyl Compounds / Q000494:pharmacology; D002268:Carboxypeptidases / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D002417:Cattle; D002918:Chymotrypsin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004352:Drug Resistance, Microbial; D004589:Electrophoresis, Disc; D004591:Electrophoresis, Polyacrylamide Gel; D007531:Isoflurophate / Q000008:administration & dosage / Q000494:pharmacology; D007700:Kinetics; D007780:Lacticaseibacillus casei / Q000201:enzymology*; D046911:Macromolecular Substances; D008727:Methotrexate; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D010446:Peptide Fragments / Q000032:analysis; D012967:Sodium Dodecyl Sulfate; D013386:Succinates / Q000494:pharmacology; D013552:Swine; D013940:Thymidylate Synthase / Q000032:analysis / Q000037:antagonists & inhibitors; D014357:Trypsin / Q000494:pharmacology
D000596:Amino Acids; D001593:Benzyl Compounds; D046911:Macromolecular Substances; D010446:Peptide Fragments; D013386:Succinates; D007531:Isoflurophate; D012967:Sodium Dodecyl Sulfate; D008780:Methyltransferases; D013940:Thymidylate Synthase; D002268:Carboxypeptidases; D002918:Chymotrypsin; D014357:Trypsin; D008727:Methotrexate