The efficacy of animal studies in predicting clinical toxicity of cancer chemotherapeutic drugs.
D000477:Alkylating Agents / Q000633:toxicity; D000818:Animals; D000963:Antimetabolites / Q000633:toxicity; D000970:Antineoplastic Agents / Q000097:blood / Q000633:toxicity*; D002318:Cardiovascular Diseases / Q000139:chemically induced; D056486:Chemical and Drug Induced Liver Injury; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D005188:False Negative Reactions; D005189:False Positive Reactions; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D000882:Haplorhini; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced; D007970:Leukopenia / Q000139:chemically induced; D009461:Neurologic Manifestations; D012044:Regression Analysis; D012877:Skin Manifestations; D013045:Species Specificity; D013921:Thrombocytopenia / Q000139:chemically induced
D000477:Alkylating Agents; D000963:Antimetabolites; D000970:Antineoplastic Agents