Biological assay of streptonigrin (NSC 45383) in body fluids and tissues of mice.
Streptonigrin, a quinone antitumor antibiotic, has been reported to be effective in human trials. A sensitive and precise microbiological assay for the determination of distribution and concentrations of streptonigrin in the body fluids and tissues of treated mice has been developed in an attempt to supplement successful clinical application of this drug.
D000818:Animals; D001412:Bacillus subtilis / Q000187:drug effects; D001681:Biological Assay; D001826:Body Fluids / Q000032:analysis*; D008722:Methods; D051379:Mice; D008815:Mice, Inbred Strains; D013308:Streptonigrin / Q000032:analysis* / Q000494:pharmacology
D013308:Streptonigrin