Cell-mediated immune responses in vitro: interaction of thymus-derived cells during cytotoxic allograft responses in vitro.
A mouse in vitro allograft system was used to check for synergism among thymus-derived cells during cell-mediated immune responses. Synergistic interactions occurred between thymus and thymus-derived lymphocytes. The majority of precursors of cytotoxic effector cells were peripheral thymus-derived cells; thymocytes acted mainly as amplifier cells.
D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D002859:Chromium Isotopes; D003601:Cytotoxicity Tests, Immunologic; D006648:Histocompatibility; D066298:In Vitro Techniques; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D012515:Mast-Cell Sarcoma / Q000276:immunology; D051379:Mice; D008806:Mice, Inbred AKR; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D013154:Spleen / Q000166:cytology / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology*
D002859:Chromium Isotopes