Delayed recovery of function following orbital prefrontal lesions in infant monkeys.
Monkeys given orbital prefrontal lesions at 1, 4, or 8 weeks of age exhibited a severe learning disability when they were tested at 1 year of age, but showed substantial recovery by the time they were 2 years old. These results suggest that the protracted maturation of intact cortical regions is important in recovery of function after early brain injury.
D000367:Age Factors; D000818:Animals; D003714:Denervation; D004193:Discrimination Learning; D005625:Frontal Lobe / Q000254:growth & development / Q000502:physiology*; D000882:Haplorhini; D008251:Macaca; D009915:Orbit