Ecto-enzyme of granulocytes: 5'-nucleotidase.
The 5'-nucleotidase of guinea pig polymorphonuclear leukocytes is localized exclusively on the plasma membrane of intact cells. The active site of this enzyme faces the external medium, not the cytoplasm.
D000249:Adenosine Monophosphate / Q000378:metabolism; D000588:Amines / Q000494:pharmacology; D000818:Animals; D001557:Benzenesulfonates / Q000494:pharmacology; D001665:Binding Sites; D002462:Cell Membrane / Q000201:enzymology; D003979:Diazonium Compounds / Q000494:pharmacology; D004492:Edetic Acid / Q000494:pharmacology; D006168:Guinea Pigs; D007770:L-Lactate Dehydrogenase / Q000097:blood; D007962:Leukocytes / Q000166:cytology / Q000201:enzymology*; D009708:Nucleotidases / Q000037:antagonists & inhibitors / Q000097:blood*; D010761:Phosphorus Radioisotopes; D013439:Sulfhydryl Reagents / Q000494:pharmacology
D000588:Amines; D001557:Benzenesulfonates; D003979:Diazonium Compounds; D010761:Phosphorus Radioisotopes; D013439:Sulfhydryl Reagents; D000249:Adenosine Monophosphate; D004492:Edetic Acid; D007770:L-Lactate Dehydrogenase; D009708:Nucleotidases