The actions of prostaglandins E2 and F2alpha on human foetal intestine.
Human foetal small and large intestine responded to prostaglandins E(2) and F(2alpha), the gestational age of the tissue being between 14 and 26 weeks. The predominant response to both prostaglandins was a contraction of each region of the intestine studied. The response to both prostaglandins was antagonized selectively by poly.phloretin phosphate.
D000028:Abortion, Induced; D000109:Acetylcholine / Q000494:pharmacology; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D007420:Intestine, Large / Q000187:drug effects; D007421:Intestine, Small / Q000187:drug effects; D007422:Intestines / Q000196:embryology; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects*; D009638:Norepinephrine / Q000494:pharmacology; D010693:Phloretin / Q000494:pharmacology; D011247:Pregnancy; D011448:Prostaglandin Antagonists; D011453:Prostaglandins / Q000494:pharmacology*; D012601:Scopolamine / Q000494:pharmacology
D011448:Prostaglandin Antagonists; D011453:Prostaglandins; D012601:Scopolamine; D000109:Acetylcholine; D010693:Phloretin; D009638:Norepinephrine