The Bacillus Subtilis genome: replication-order and map-position discrepancies--evidence for a second origin.
Replication order to map position discrepancies have been documented in B. subtilis. The discrepancies were found to occur whenever the genome of B. subtilis was replicated under a variety of physiological conditions and in both 168 and W23 strains. The earliest replicating marker involved in these discrepancies was thr versus purB and aroA versus recA. A detailed linkage analysis of the ura to argA region was consistent with its being a continuous linkage group. This led to the conclusion that an origin for new starts at replication exists between recA and aroA.
D001412:Bacillus subtilis; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D004261:DNA Replication; D004269:DNA, Bacterial; D005787:Gene Frequency; D005815:Genetic Code; D008040:Genetic Linkage; D005838:Genotype; D014161:Transduction, Genetic; D014170:Transformation, Genetic
D004269:DNA, Bacterial