Recombination in bacteriophage T4: a mechanism.
Genetic recombination between rIl mutants of T4 bacteriophage grown in Escherichia coli can occur under conditions where DNA synthesis is strongly inhibited by 5-fluorodeoxyuridine. The small amount of DNA synthesized under these conditions cannot account for the observed frequency of recombinants. The major mechanism of recombination in this system is a process of breakage and rejoining.
D002701:Chloramphenicol / Q000494:pharmacology; D003090:Coliphages; D004279:DNA, Viral / Q000096:biosynthesis*; D005467:Floxuridine / Q000494:pharmacology*; D066298:In Vitro Techniques; D009154:Mutation; D010759:Phosphorus Isotopes; D011687:Purines / Q000494:pharmacology; D011874:Radiometry
D004279:DNA, Viral; D010759:Phosphorus Isotopes; D011687:Purines; D005467:Floxuridine; D002701:Chloramphenicol