Structure-activity relationships within the class of 1,4-benzodiazepines: presence of chlorine and central nervous system activities.
D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology; D001570:Benzodiazepinones / Q000494:pharmacology*; D002713:Chlorine / Q000494:pharmacology*; D004357:Drug Synergism; D005260:Female; D006591:Hexobarbital / Q000494:pharmacology; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009125:Muscle Relaxants, Central / Q000494:pharmacology; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D012890:Sleep / Q000187:drug effects; D013329:Structure-Activity Relationship; D013331:Strychnine / Q000037:antagonists & inhibitors
D000927:Anticonvulsants; D001570:Benzodiazepinones; D009125:Muscle Relaxants, Central; D002713:Chlorine; D006591:Hexobarbital; D013331:Strychnine; D010433:Pentylenetetrazole