Amine functions of reduced basicity. Hypoglycemic and natriuretic alpha-alkoxybenzylamidoximes, amidines, and cycloamidines.
D000578:Amidines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure / Q000187:drug effects; D002415:Cats; D003061:Codeine; D004285:Dogs; D000882:Haplorhini; D006852:Hydrochlorothiazide / Q000494:pharmacology; D006977:Hypertension, Renal / Q000378:metabolism; D007004:Hypoglycemic Agents / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D066298:In Vitro Techniques; D007700:Kinetics; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D009318:Natriuresis / Q000187:drug effects*; D010089:Oxidoreductases, N-Demethylating / Q000037:antagonists & inhibitors; D010091:Oximes / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship
D000578:Amidines; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010091:Oximes; D006852:Hydrochlorothiazide; D011335:Proadifen; D010089:Oxidoreductases, N-Demethylating; D003061:Codeine