Multiplication of Pasteurella multocida in the spleen, liver and blood of turkeys inoculated intravenously.
After intravenous inoculation of Pasteurella multocida into turkeys the number of organisms increased over 100 times in the liver and 75 times in the spleen three hours after inoculation, but there was no increase in the blood. Between three and 15 hours after inoculation there was no change in the number of organisms in the liver and spleen. The number of organisms rose steadily between 15 and 22 hours after inoculation. After 22 hours there was a very significant increase in numbers of organisms in the liver, spleen and blood. It was found that the increase in number of organisms in the blood occurred rapidly between 22 and 28 hours after inoculation when the number of bacteria in the liver and spleen reached its peak. It appears that the bacteria from the liver and spleen invaded the blood before the death of the turkeys.
D000818:Animals; D008099:Liver / Q000382:microbiology; D010325:Pasteurella / Q000254:growth & development*; D010326:Pasteurella Infections / Q000097:blood / Q000150:complications / Q000662:veterinary*; D011201:Poultry Diseases; D013154:Spleen / Q000382:microbiology; D014422:Turkeys