title: Enzyme activity and composition of myelin and subcellular fractions in the developing rat brain.
abstract: 1. Subcellular fractions and myelin were isolated from developing and adult rat brain. 2. Measurements of chemical composition and enzyme activities indicate the presence of a second myelin-like fraction mainly in the brain of developing rats. 3. This membrane fraction has a different lipid composition from myelin, but resembles myelin in its content of phosphohydrolase and aminopeptidase activity. 4. It is suggested that the second myelin-like fraction may be a submicrosomal contaminant or it may be derived from oligodendroglial plasma membrane during myelinogenesis.
mesh_terms: D000110:Acetylcholinesterase / Q000032:analysis; D000251:Adenosine Triphosphatases / Q000032:analysis; D000818:Animals; D001921:Brain / Q000166:cytology / Q000201:enzymology* / Q000254:growth & development*; D002802:Cholinesterases / Q000032:analysis; D004950:Esterases / Q000032:analysis; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D008297:Male; D008854:Microscopy, Electron; D008861:Microsomes / Q000032:analysis; D009186:Myelin Sheath / Q000032:analysis*; D009696:Nucleic Acids / Q000032:analysis; D011506:Proteins / Q000032:analysis; D051381:Rats
chemical_list: D005227:Fatty Acids; D009696:Nucleic Acids; D011506:Proteins; D004950:Esterases; D000110:Acetylcholinesterase; D002802:Cholinesterases; D000251:Adenosine Triphosphatases