Mechanism of selective cardiac vagolytic action of pancuronium bromide. Specific blockade of cardiac muscarinic receptors.
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D001011:Aorta / Q000187:drug effects; D001285:Atropine / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D002217:Carbachol / Q000494:pharmacology; D002219:Carbamates / Q000494:pharmacology; D002415:Cats; D004285:Dogs; D004558:Electric Stimulation; D005260:Female; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects*; D006325:Heart Atria; D006339:Heart Rate / Q000187:drug effects; D007082:Ileum; D008297:Male; D008688:Methacholine Compounds / Q000494:pharmacology; D003473:Neuromuscular Nondepolarizing Agents / Q000494:pharmacology*; D010277:Parasympathomimetics / Q000494:pharmacology; D010477:Perfusion; D010879:Piperazines / Q000494:pharmacology; D011189:Potassium Chloride / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D011984:Sensory Receptor Cells / Q000187:drug effects; D013566:Sympathomimetics / Q000494:pharmacology; D014628:Vagotomy; D014630:Vagus Nerve / Q000502:physiology; D014655:Vascular Resistance / Q000187:drug effects
D002219:Carbamates; D008688:Methacholine Compounds; D003473:Neuromuscular Nondepolarizing Agents; D010277:Parasympathomimetics; D010879:Piperazines; D000644:Quaternary Ammonium Compounds; D013566:Sympathomimetics; D011189:Potassium Chloride; D001285:Atropine; D002217:Carbachol; D000109:Acetylcholine