[Qualitative changes in liver microsomes of phenobarbital-treated rabbits. Changes in spectral dissociation constants (Ks) of aniline and N-ethylaniline, in the apparent Michaelis constants (Km) for hydroxylation of these substrates, and in affinity of the enzymes involved for oxygen and carbon monoxide].
D000814:Aniline Compounds / Q000378:metabolism*; D000818:Animals; D002248:Carbon Monoxide / Q000378:metabolism*; D003486:Cyanides / Q000378:metabolism; D004790:Enzyme Induction / Q000187:drug effects; D007700:Kinetics; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology*; D011817:Rabbits
D000814:Aniline Compounds; D003486:Cyanides; D002248:Carbon Monoxide; D010100:Oxygen; D010634:Phenobarbital
Qualitative Anderungen in Lebermikrosomen Phenobarbital-behandelter Kaninchen. Anderungen der spektralen Dissoziationskonstanten (Ks) von Anilin und N-Athylanilin, der scheinbaren Michaelis-Konstanten (Km) für die Hydroxylierung dieser Substrate und der Affinität der beteiligten Enzyme für Sauerstoff und Kohlenmonoxid.