Glycolytic enzymes in adipose tissue of adult diabetics.
The maximal activities of hexokinase and phosphofructokinase were measured in human adipose tissue. Though the mean activity of hexokinase was similar between a group of adult diabetics (n=24) and a group of non-diabetic controls (n=25), in the diabetic group the activity of phosphofructokinase was definitely reduced. Possibly this enzyme deficiency might contribute to impaired glucose utilization by the adipose cell in diabetes.
D000273:Adipose Tissue / Q000201:enzymology*; D000328:Adult; D003920:Diabetes Mellitus / Q000201:enzymology*; D006593:Hexokinase / Q000032:analysis / Q000378:metabolism*; D006801:Humans; D010732:Phosphofructokinase-1 / Q000032:analysis / Q000378:metabolism*; D013053:Spectrophotometry
D006593:Hexokinase; D010732:Phosphofructokinase-1