Ribonucleic acid control of steroid synthesis in human adrenals and testes.
The pattern of steroid synthesis in human fetal testes and adrenals was altered by prior exposure, in organ culture of the explants, of one gland to the ribonucleic acid extracted from the other gland. The new pattern reflected the origin of the RNA.
D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism*; D000728:Androgens / Q000096:biosynthesis*; D000818:Animals; D003345:Corticosterone / Q000096:biosynthesis*; D046508:Culture Techniques; D003687:Dehydroepiandrosterone / Q000096:biosynthesis*; D005333:Fetus; D006801:Humans; D006854:Hydrocortisone / Q000096:biosynthesis*; D006908:Hydroxyprogesterones / Q000096:biosynthesis*; D006913:Hydroxysteroid Dehydrogenases / Q000378:metabolism; D008297:Male; D051379:Mice; D011284:Pregnenolone / Q000378:metabolism*; D012313:RNA / Q000494:pharmacology*; D013256:Steroids / Q000096:biosynthesis*; D013737:Testis / Q000187:drug effects / Q000196:embryology / Q000378:metabolism*; D013739:Testosterone / Q000096:biosynthesis*; D014316:Tritium
D000728:Androgens; D006908:Hydroxyprogesterones; D013256:Steroids; D014316:Tritium; D013739:Testosterone; D003687:Dehydroepiandrosterone; D012313:RNA; D011284:Pregnenolone; D006913:Hydroxysteroid Dehydrogenases; D003345:Corticosterone; D006854:Hydrocortisone