title: Response of ferrets and monkeys to intranasal infection with human, equine and avian influenza viruses.
abstract: Rhesus monkeys and ferrets were exposed to intranasal inoculation of several strains of egg-adapted avian, equine and human influenza viruses and to strains of mouse-adapted equine influenza viruses. Local replication of virus and seroconversion were observed in the majority of these animals. However, clinical infection was observed only in ferrets.
mesh_terms: D000818:Animals; D000937:Antigen-Antibody Reactions; D001717:Birds; D002335:Carnivora; D003429:Cross Reactions; D000882:Haplorhini; D006385:Hemagglutination Inhibition Tests; D006736:Horses; D006801:Humans; D007106:Immune Sera; D007251:Influenza, Human / Q000276:immunology / Q000662:veterinary*; D008992:Monkey Diseases / Q000382:microbiology*; D009666:Nose / Q000382:microbiology*; D009975:Orthomyxoviridae / Q000302:isolation & purification / Q000472:pathogenicity*; D012141:Respiratory Tract Infections / Q000276:immunology / Q000382:microbiology*; D014422:Turkeys; D014779:Virus Replication
chemical_list: D007106:Immune Sera