title: Treatment of acne vulgaris with tetracycline hydrochloride: a double-blind trial with 51 patients.
abstract: Fifty-one patients with acne vulgaris were included in a double-blind trial to assess the therapeutic effect of 250 mg. tetracycline hydrochloride twice daily for three months. The results, assessed clinically and photographically, showed that tetracycline hydrochloride had a statistically significant beneficial effect. Hence, since it is cheap and rarely has side-effects in healthy young adults, its use is suggested, as well as local therapy, in the more severe forms of acne.
mesh_terms: D000152:Acne Vulgaris / Q000145:classification / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D002648:Child; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008297:Male; D010781:Photography; D010919:Placebos; D013223:Statistics as Topic; D013752:Tetracycline / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D010919:Placebos; D013752:Tetracycline