title: Laboratory experiments on the control of cyclops transmitting guinea worm.
abstract: Infection with the guinea worm (Dracunculus medinensis) affects millions of people living in rural areas in certain parts of the world. Usually, the standard of living is low and elaborate control measures would not be feasible. In this study, various insecticidal and molluscicidal compounds were tested in the laboratory for their toxicity to the intermediate hosts, namely, various species of cyclops, which often live in sources of potable water, such as step-wells, cisterns and ponds. Cheapness, low toxicity to mammals and ease of application, in conjunction with effectiveness against cyclops, are primary requisites for any compound accepted for widespread use. Abate, an insecticide, has been shown to be particularly promising in these respects. The timing and mode of application of compounds toxic to cyclops in various endemic regions are discussed.
mesh_terms: D000818:Animals; D003445:Crustacea / Q000187:drug effects*; D004199:Disease Vectors; D004320:Dracunculiasis / Q000517:prevention & control*; D006801:Humans; D007306:Insecticides / Q000494:pharmacology*; D008975:Molluscacides / Q000494:pharmacology*; D014881:Water Supply
chemical_list: D007306:Insecticides; D008975:Molluscacides