Studies on viral plasmacytosis (Aleutian disease) of mink. VII. Infection of mink with DNA extracted from diseased spleens.
Lesions considered typical of aleutian disease developed in three of four mink inoculated with DNA extracted from spleens of mink with viral plasmacytosis. Control mink inoculated with buffered saline or DNA treated with specific enzyme (DNAase) remained normal. It is inferred that the infective DNA corresponds to viral DNA. This DNA preparation was used in an attempt to infect tissue cultures from mink testis cells but the results were equivocal.
D000818:Animals; D002335:Carnivora; D003588:Cytopathogenic Effect, Viral / Q000662:veterinary; D004279:DNA, Viral; D010950:Plasma Cells; D013154:Spleen; D014777:Virus Diseases / Q000209:etiology*
D004279:DNA, Viral