Actomyosin-like protein isolated from mammalian brain.
A protein with characteristics similar to actomyosin has been isolated from whole brain of rat and cat. It is soluble in 0.6 molar potassium chloride and insoluble in 0.1 molar potassium chloride. It superprecipitates with magnesium ions and adenosine triphosphate. It has adenosine triphosphatase activity stimulated by either magnesium or calcium ions. Both superprecipitation and adenosine triphosphatase activity are inhibited by p-chloromercuribenzoate and Mersalyl but not by ouabain.
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001923:Brain Chemistry; D002118:Calcium / Q000494:pharmacology; D002415:Cats; D011232:Chemical Precipitation; D002729:Chloromercuribenzoates / Q000494:pharmacology; D003864:Depression, Chemical; D008274:Magnesium / Q000494:pharmacology; D009124:Muscle Proteins; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009941:Organomercury Compounds / Q000494:pharmacology; D011189:Potassium Chloride / Q000494:pharmacology; D051381:Rats; D013268:Stimulation, Chemical
D002729:Chloromercuribenzoates; D009124:Muscle Proteins; D009419:Nerve Tissue Proteins; D009941:Organomercury Compounds; D011189:Potassium Chloride; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases; D008274:Magnesium; D002118:Calcium