Fibrinogen catabolism study of three patients with bacterial endocarditis and renal disease.
Three patients with bacterial endocarditis who developed renal failure have been studied by means of a radiofibrinogen catabolism study. Two were studied at the time of bacteraemia and one during the subsequent "immunological phase" of circulating immune complexes. Accelerated fibrinogen catabolism was found in all cases. Intravascular coagulation may be an important factor in the pathogenesis of proliferative glomerulonephritis in such cases.
D058186:Acute Kidney Injury / Q000378:metabolism*; D000328:Adult; D000740:Anemia / Q000150:complications; D004211:Disseminated Intravascular Coagulation / Q000150:complications; D004697:Endocarditis, Bacterial / Q000378:metabolism*; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D005921:Glomerulonephritis / Q000209:etiology; D006801:Humans; D007105:Immune Complex Diseases; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D011868:Radioisotopes; D006435:Renal Dialysis
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D011868:Radioisotopes; D005340:Fibrinogen