Quantitative assay of pyrazofurin, a new antiviral, antitumor antibiotic.
Pyrazofurin, a carbon-linked nucleoside, has been previously reported to possess antiviral and antitumor activity. The antagonistic effect of pyrazofurin against Neurospora crassa has been utilized to develop a quantitative assay for the compound.
D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D000998:Antiviral Agents / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D009491:Neurospora / Q000187:drug effects*; D009492:Neurospora crassa / Q000187:drug effects; D011720:Pyrazoles / Q000494:pharmacology*; D012263:Ribonucleosides / Q000494:pharmacology*
D000903:Antibiotics, Antineoplastic; D000998:Antiviral Agents; D011720:Pyrazoles; D012263:Ribonucleosides