Synthesis and pharmacology of an epoxide derivative of ethacrynic acid.
D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors; D000818:Animals; D003545:Cysteine / Q000378:metabolism; D004231:Diuresis / Q000187:drug effects; D004976:Ethacrynic Acid / Q000138:chemical synthesis* / Q000494:pharmacology; D004988:Ethers, Cyclic / Q000138:chemical synthesis* / Q000494:pharmacology; D005919:Glomerular Filtration Rate; D007668:Kidney / Q000201:enzymology; D007700:Kinetics; D011188:Potassium; D011485:Protein Binding / Q000187:drug effects; D012964:Sodium; D013329:Structure-Activity Relationship; D013438:Sulfhydryl Compounds / Q000378:metabolism
D004988:Ethers, Cyclic; D013438:Sulfhydryl Compounds; D012964:Sodium; D000251:Adenosine Triphosphatases; D003545:Cysteine; D004976:Ethacrynic Acid; D011188:Potassium