Immune responses in vitro. IX. Absence of the mixed leukocyte stimulatory, M-locus product from thymus cells.
The mixed leukocyte reaction stimulatory M-locus product of DBA/2 spleen cells was absent from thymus cells. The absence of stimulation was not a result of suppressor T cells. These findings are discussed in relation to the divergent specificity found for the inductive and effector phases of cell-mediated responses.
D000818:Animals; D005260:Female; D007111:Immunity, Cellular; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000276:immunology* / Q000528:radiation effects; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008811:Mice, Inbred DBA; D011830:Radiation Effects; D013154:Spleen / Q000166:cytology*; D013936:Thymidine / Q000378:metabolism; D013950:Thymus Gland / Q000166:cytology*; D014316:Tritium
D014316:Tritium; D013936:Thymidine