Participation of an intermediate sulfoxide in the enzymatic thiolation of the imidazole ring of hercynine to form ergothioneine.
D001622:Betaine / Q000378:metabolism; D002250:Carbon Radioisotopes; D002384:Catalysis; D002474:Cell-Free System; D004880:Ergothioneine / Q000096:biosynthesis* / Q000138:chemical synthesis / Q000302:isolation & purification; D006639:Histidine / Q000378:metabolism*; D006898:Hydroxylamines / Q000494:pharmacology; D007093:Imidazoles / Q000378:metabolism; D007501:Iron / Q000494:pharmacology; D009491:Neurospora / Q000201:enzymology / Q000378:metabolism*; D009492:Neurospora crassa / Q000201:enzymology / Q000378:metabolism; D010100:Oxygen; D011199:Potentiometry; D011732:Pyridoxal Phosphate / Q000494:pharmacology; D011773:Pyruvates / Q000378:metabolism; D013454:Sulfoxides / Q000302:isolation & purification / Q000378:metabolism*; D013462:Sulfur Radioisotopes
D002250:Carbon Radioisotopes; D006898:Hydroxylamines; D007093:Imidazoles; D011773:Pyruvates; D013454:Sulfoxides; D013462:Sulfur Radioisotopes; D001622:Betaine; D006639:Histidine; D011732:Pyridoxal Phosphate; D004880:Ergothioneine; D007501:Iron; D010100:Oxygen