title: Biogenic amines and head twitches in mice during ethanol withdrawal.
abstract: After chronic administration of ethanol to mice by the intragastric route head twitches occur as part of the ethanol withdrawal syndrome. Treatments which reduce brain 5-hydroxytryptamine or increase brain noradrenaline inhibited ethanol withdrawal head twitches, whereas treatments which increase brain 5-hydroxytryptamine or reduce brain noradrenaline were capable of inducing head twitches in control animals.
mesh_terms: D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000661:Amphetamine / Q000494:pharmacology; D000662:Amphetamines; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001679:Biogenic Amines / Q000378:metabolism*; D002552:Cerebral Ventricles; D004873:Ergolines / Q000494:pharmacology; D000431:Ethanol; D010134:Fenclonine / Q000494:pharmacology; D006257:Head; D006801:Humans; D007267:Injections; D008297:Male; D008781:Methyltyrosines / Q000494:pharmacology; D008784:Methysergide / Q000494:pharmacology; D051379:Mice; D009068:Movement / Q000187:drug effects*; D009638:Norepinephrine / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D012702:Serotonin Antagonists; D013375:Substance Withdrawal Syndrome
chemical_list: D000662:Amphetamines; D001679:Biogenic Amines; D004873:Ergolines; D008781:Methyltyrosines; D012702:Serotonin Antagonists; D012701:Serotonin; D000431:Ethanol; D006916:5-Hydroxytryptophan; D000661:Amphetamine; D010134:Fenclonine; D009638:Norepinephrine; D008784:Methysergide