Structue-activity relationships of cardiotonic steroids for the inhibition of sodium- and potassium-dependent adenosine triphosphatase. I. Dissociation rate constants of various enzyme-cardiac glycoside complexes formed in the presence of magnesium and phosphate.
D000107:Acetylation; D000251:Adenosine Triphosphatases / Q000032:analysis / Q000037:antagonists & inhibitors*; D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000166:cytology / Q000201:enzymology; D002241:Carbohydrates; D002297:Cardanolides; D002301:Cardiac Glycosides / Q000494:pharmacology*; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D004355:Drug Stability; D007700:Kinetics; D008274:Magnesium; D009682:Magnetic Resonance Spectroscopy; D008861:Microsomes; D010042:Ouabain / Q000494:pharmacology; D010710:Phosphates; D011188:Potassium; D012964:Sodium; D013328:Strophanthins / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013696:Temperature
D002241:Carbohydrates; D002297:Cardanolides; D002301:Cardiac Glycosides; D010710:Phosphates; D013328:Strophanthins; D010042:Ouabain; D012964:Sodium; D000251:Adenosine Triphosphatases; D008274:Magnesium; D011188:Potassium