Conversion of spironolactone to canrenone and disposition kinetics of spironolactone and canrenoate-potassium in rats.
D000818:Animals; D001673:Biodegradation, Environmental; D002855:Chromatography, Thin Layer; D005260:Female; D006207:Half-Life; D006868:Hydrolysis; D007700:Kinetics; D013058:Mass Spectrometry; D008657:Metabolic Clearance Rate; D000451:Mineralocorticoid Receptor Antagonists; D008956:Models, Chemical; D051381:Rats; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013148:Spironolactone / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology; D013997:Time Factors; D014316:Tritium
D000451:Mineralocorticoid Receptor Antagonists; D014316:Tritium; D013148:Spironolactone