Bovine viral diarrhea virus in swine: neutralizing antibody in naturally and experimentally infected swine.
Neutralizing antibodies against bovine viral diarrhea virus (BVDV) were detected in sera of Iowa farm sows, their piglets derived by hysterectomy and in specific-pathogen-free (SPF) pigs in a closed herd. No antibodies against BVDV were detected in sera of 134 fetal pigs from 67 sows in an Iowa slaughter-house. Neutralizing antibodies against BVDV or hog cholera virus, produced experimentally in SPF pigs, were demonstrated to be due to different antigens rather than to a common antigen, although slight cross-neutralization reactions sometimes occur.
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000008:administration & dosage; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000209:etiology / Q000276:immunology; D002417:Cattle; D002418:Cattle Diseases; D002478:Cells, Cultured; D006691:Classical Swine Fever / Q000209:etiology; D005260:Female; D005333:Fetus / Q000276:immunology; D005856:Germ-Free Life; D007044:Hysterectomy; D007273:Injections, Intramuscular; D007668:Kidney; D008431:Maternal-Fetal Exchange; D009500:Neutralization Tests; D011247:Pregnancy; D012328:RNA Viruses / Q000276:immunology*; D013552:Swine; D013553:Swine Diseases / Q000276:immunology* / Q000382:microbiology; D014776:Virus Cultivation; D014777:Virus Diseases / Q000662:veterinary*
D000914:Antibodies, Viral; D000956:Antigens, Viral