title: Chronological development of Mycoplasma hyorhinis and Mycoplasma hyosynoviae infections in cultures of a swine synovial cell strain.
abstract: The sequential development of Mycroplasma hyorhinis and Mycoplasma hyosynoviae was observed in cultures of a swine synovial fluid cell strain. An early transitory filamentous phase was observed with M. hyorhinis infection followed by the development of cell-associated, relatively large, round structures and some ring forms. Infection with M. hyorhinis was characterized by a generalized distribution of the organism and a severe cytopathic effect. Infection with M. hyosynoviae was represented by the development of circumscribed foci of small pleomorphic structures and a milder effect on the cells. At a high multiplicity of infection, this organism became associated with the cytoplasmic membranes of the cells.
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D005455:Fluorescent Antibody Technique; D009174:Mycoplasma / Q000254:growth & development*; D009175:Mycoplasma Infections / Q000473:pathology / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000473:pathology; D013582:Synovial Fluid / Q000166:cytology*; D013997:Time Factors