R factor elimination by inhibitors of thymidylate synthetase (fluorodeoxyuridine and showdomycin) and the occurrence of single strand breaks in plasmid DNA.
D000903:Antibiotics, Antineoplastic; D004269:DNA, Bacterial; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000201:enzymology; D005111:Extrachromosomal Inheritance; D005467:Floxuridine; D005472:Fluorouracil; D005827:Genetics, Microbial; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D008967:Molecular Biology; D009705:Nucleosides; D013936:Thymidine / Q000494:pharmacology; D014500:Uracil Nucleotides
D000903:Antibiotics, Antineoplastic; D004269:DNA, Bacterial; D009705:Nucleosides; D014500:Uracil Nucleotides; D005467:Floxuridine; D008780:Methyltransferases; D005472:Fluorouracil; D013936:Thymidine