title: Immunity to Escherichia coli in pigs: antibody secretion by the mammary gland after intramammary or intramuscular vaccination with an E. coli vaccine.
abstract: Indirect hemagglutinating antibody titres in individual gland samples of colostrum and milk from 13 sows were measured. Five of the sows were vaccinated via a mammary gland and five by the intramuscular route with a live formalinised Escherichia coli vaccine and three remained as non-vaccinated controls. Antibody titres were higher in colostral and milk whey from the vaccinated sows than from non-vaccinated groups. The inoculated gland in the group of sows given vaccine by the intramammary route secreted milk containing markedly more antibodies to the vaccine E. coli strain than did the non-vaccinated glands. Milk from the vaccinated gland did not contain higher titres to heterologous E. coli O antigens than milk from non-vaccinated glands. Serum titres were the same or higher than the titres in colostrum from non-vaccinated glands.
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis*; D000942:Antigens, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines / Q000008:administration & dosage*; D003126:Colostrum / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology*; D005260:Female; D006386:Hemagglutination Tests; D007267:Injections; D007273:Injections, Intramuscular; D008321:Mammary Glands, Animal / Q000276:immunology*; D008892:Milk / Q000276:immunology; D011247:Pregnancy; D013552:Swine / Q000276:immunology*
chemical_list: D000906:Antibodies; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines