The induction of ATP energized mitochondrial volume changes by showdomycin when combined with 4',8'-dihydroxy-1,2,5,6-dibenz-9,10-anthraquinone, a metabolite of the carcinogenic polynuclear hydrocarbon dibenz(A,H) anthracene.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000255:Adenosine Triphosphate; D000880:Anthraquinones / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001551:Benz(a)Anthracenes / Q000378:metabolism*; D002273:Carcinogens / Q000494:pharmacology; D003864:Depression, Chemical; D004790:Enzyme Induction; D006863:Hydrogen-Ion Concentration; D008928:Mitochondria / Q000187:drug effects* / Q000378:metabolism; D009840:Oligomycins / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects; D011188:Potassium / Q000494:pharmacology; D013268:Stimulation, Chemical; D014449:Tyrothricin / Q000494:pharmacology
D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D001551:Benz(a)Anthracenes; D002273:Carcinogens; D009840:Oligomycins; D014449:Tyrothricin; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases; D011188:Potassium