title: Dissociation and reassociation of the transfer factor and resistance determinants of R factors as a mechanism of gene amplification in bacteria.
mesh_terms: D001419:Bacteria; D001483:Base Sequence; D002701:Chloramphenicol / Q000494:pharmacology; D002876:Chromosomes, Bacterial / Q000032:analysis; D003227:Conjugation, Genetic; D004261:DNA Replication; D004269:DNA, Bacterial / Q000032:analysis; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000254:growth & development; D005111:Extrachromosomal Inheritance; D005796:Genes; D008970:Molecular Weight; D009154:Mutation; D011513:Proteus mirabilis / Q000187:drug effects / Q000254:growth & development; D011995:Recombination, Genetic; D012706:Serratia marcescens / Q000254:growth & development; D000198:Spectinomycin / Q000494:pharmacology; D013307:Streptomycin / Q000494:pharmacology; D013449:Sulfonamides / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D004269:DNA, Bacterial; D013449:Sulfonamides; D002701:Chloramphenicol; D000198:Spectinomycin; D013752:Tetracycline; D013307:Streptomycin