A drug-induced cerebrospinal lipodystrophy in the domestic chicken (Gallus domesticus).
A drug-induced lipidosis of the central nervous system of chickens is reported. Membranous cytoplastic neuronal inclusions similar to those seen in Tay-sach's disease in man and in spontaneous or drug-induced disease in swine were seen by electron microscopy. Fat was demonstrated in frozen sections.
D000818:Animals; D001921:Brain / Q000473:pathology; D002371:Cat Diseases / Q000139:chemically induced / Q000473:pathology; D002415:Cats; D002493:Central Nervous System Diseases / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D002645:Chickens; D002682:Chinchilla; D002738:Chloroquine / Q000009:adverse effects*; D003594:Cytoplasmic Granules; D004195:Disease Models, Animal; D008064:Lipidoses / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D008854:Microscopy, Electron; D009474:Neurons; D010710:Phosphates / Q000009:adverse effects*; D011201:Poultry Diseases / Q000139:chemically induced* / Q000473:pathology; D013116:Spinal Cord / Q000473:pathology
D010710:Phosphates; D002738:Chloroquine