Mutagenic and recombinogenic activities of the food additive furylfuramide in eurkaryotes.
The mutagenic and recombinogenic activities of furylfuramide, an antimicrobial food additive, were tested in a two-component heterokaryon of Neurospora crassa and a diploid strain of Saccharomyces cerevisiae, respectively. The results show that furylfuramide is genetically active in both eukaryotic organisms; it induces mutations in Neurospora crassa and mitotic crossing over in Saccharomyces cerevisiae.
D000178:Acrylamides / Q000494:pharmacology*; D005503:Food Additives; D009153:Mutagens; D009154:Mutation; D009492:Neurospora crassa / Q000187:drug effects; D009581:Nitrofurans / Q000494:pharmacology*; D011995:Recombination, Genetic / Q000187:drug effects*; D012441:Saccharomyces cerevisiae / Q000187:drug effects
D000178:Acrylamides; D005503:Food Additives; D009153:Mutagens; D009581:Nitrofurans