Structure-activity relationships for the inhibition of plasmin and plasminogen activation by aromatic diamidines and a study of the effect of plasma proteins on the inhibition process.
D000578:Amidines / Q000494:pharmacology*; D000614:Aminocaproates / Q000494:pharmacology; D001798:Blood Proteins / Q000494:pharmacology*; D055598:Chemical Phenomena; D002621:Chemistry; D004789:Enzyme Activation / Q000187:drug effects; D005341:Fibrinolysin / Q000037:antagonists & inhibitors*; D006801:Humans; D007610:Kallikreins / Q000494:pharmacology; D010958:Plasminogen / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D013917:Thrombin / Q000494:pharmacology; D014357:Trypsin / Q000494:pharmacology
D000578:Amidines; D000614:Aminocaproates; D001798:Blood Proteins; D010958:Plasminogen; D007610:Kallikreins; D014357:Trypsin; D013917:Thrombin; D005341:Fibrinolysin