Affinity chromatography of thymidylate synthetases using 5-fluoro-2'-deoxyuridine 5'-phosphate derivatives of sepharose.
D001665:Binding Sites; D002846:Chromatography, Affinity; D003090:Coliphages; D003903:Deuterium; D004352:Drug Resistance, Microbial; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli / Q000201:enzymology; D005069:Evaluation Studies as Topic; D005467:Floxuridine / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D007780:Lacticaseibacillus casei / Q000187:drug effects / Q000201:enzymology; D009682:Magnetic Resonance Spectroscopy; D008722:Methods; D008727:Methotrexate / Q000494:pharmacology; D008780:Methyltransferases / Q000302:isolation & purification*; D009943:Organophosphorus Compounds; D011485:Protein Binding; D013329:Structure-Activity Relationship; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors / Q000302:isolation & purification; D014500:Uracil Nucleotides / Q000494:pharmacology
D009943:Organophosphorus Compounds; D014500:Uracil Nucleotides; D005467:Floxuridine; D003903:Deuterium; D008780:Methyltransferases; D013940:Thymidylate Synthase; D008727:Methotrexate