Decreased effect of phenobarbital treatment on microsomal drug metabolizing enzyme activity during gestation.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism; D001835:Body Weight / Q000187:drug effects; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003640:Dealkylation; D003864:Depression, Chemical; D005260:Female; D005333:Fetus / Q000187:drug effects; D006591:Hexobarbital / Q000494:pharmacology; D006900:Hydroxylation; D007700:Kinetics; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009019:Morphinans / Q000378:metabolism; D009929:Organ Size; D010634:Phenobarbital / Q000494:pharmacology*; D011247:Pregnancy; D011270:Pregnancy, Animal; D011506:Proteins / Q000378:metabolism; D051381:Rats; D012890:Sleep / Q000187:drug effects; D013997:Time Factors; D014599:Uterus / Q000187:drug effects
D001580:Benzopyrenes; D009019:Morphinans; D011506:Proteins; D003577:Cytochrome P-450 Enzyme System; D006591:Hexobarbital; D006899:Mixed Function Oxygenases; D010634:Phenobarbital