[The allergenic effect of rubber accelerators tetramethyl thiuram disulfide (TMTD) and mercaptobenzothiazole (MBT)].
The eczematogenic effects of tetramethylthiuramidsulfid and of mercaptobenzothiazol were studied on the basis of an inquiry in establishments using TMTD and MBT, a frequency analysis of positive reactions of our standard series in 1971 and testing of various rubber articles on sensitized persons as well as animal experiments. The results indicate a wider use, a higher percentage of positive epicutaneous tests and also a higher sensitizing potency in the animal test of the TMTD as compared with MBT. MBT was removed from our standard series.
D000485:Allergens; D003877:Dermatitis, Contact / Q000209:etiology*; D004864:Equipment and Supplies; D004865:Equipment and Supplies, Hospital; D005859:Germany, East; D006801:Humans; D012408:Rubber; D012882:Skin Tests; D013844:Thiazoles / Q000009:adverse effects*; D013859:Thiocarbamates / Q000009:adverse effects*; D013893:Thiram / Q000009:adverse effects*
D000485:Allergens; D013844:Thiazoles; D013859:Thiocarbamates; D013893:Thiram; D012408:Rubber
Die allergene Wirkung der Gummiakzeleratoren Tetramethylthiuramdisulfid (TMTD) und Mercaptobenzothiazol (MBT)