On the mechanism of the inhibitory action of the spirolactone SC 9376 (aldadiene) on the production of corticosteroids in rat adrenals in vitro.
D000311:Adrenal Glands / Q000378:metabolism*; D000450:Aldosterone / Q000096:biosynthesis*; D000731:Androstanes / Q000494:pharmacology; D000818:Animals; D002297:Cardanolides / Q000494:pharmacology*; D003345:Corticosterone / Q000096:biosynthesis*; D004032:Diet; D004305:Dose-Response Relationship, Drug; D007664:Ketosteroids / Q000494:pharmacology; D008297:Male; D013058:Mass Spectrometry; D000451:Mineralocorticoid Receptor Antagonists; D051381:Rats; D012964:Sodium; D013148:Spironolactone / Q000494:pharmacology
D000731:Androstanes; D002297:Cardanolides; D007664:Ketosteroids; D000451:Mineralocorticoid Receptor Antagonists; D013148:Spironolactone; D000450:Aldosterone; D012964:Sodium; D003345:Corticosterone