title: In vitro studies of group E streptococci in swine leukocytes. I. Phagocytic and bactericidal properties of polymorphonuclear leukocytes from swine.
abstract: Serum from both immune and nonimmune ten-week-old swine contained factors which promoted phagocytosis of group E Streptococci (GES). The factors in nonimmune serum, which were heat labile at 70 degrees C for ten minutes, were less efficient than the factors present in immune serum.Bactericidal activity of the polymorphonuclear (PMN) leukocytes against GES was observed with serum from both immune and nonimmune ten-week-old swine, as well as with serum from normal sows and piglets. However, the bactericidal activity of PMN leukocytes in serum from either normal sows or immune ten-week-old swine was greater than the bactericidal activity of PMN leukocytes in either piglet serum or serum from nonimmune ten-week-old swine. When the serum was either heated to 70 degrees C for ten minutes or treated with 2-mercaptoethanol, bactericidal activity of PMN leukocytes against GES was only observed in the presence of immune serum.
mesh_terms: D000818:Animals; D000936:Antigen-Antibody Complex; D005260:Female; D006358:Hot Temperature; D007106:Immune Sera; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D066298:In Vitro Techniques; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology*; D008623:Mercaptoethanol / Q000494:pharmacology; D010586:Phagocytes / Q000276:immunology; D010587:Phagocytosis; D013291:Streptococcus / Q000187:drug effects / Q000276:immunology*; D013552:Swine
chemical_list: D000936:Antigen-Antibody Complex; D007106:Immune Sera; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008623:Mercaptoethanol