Cutaneous and ocular reactions to practolol.
A total of 21 patients suffering from drug-induced rashes from practolol have been seen over the past two years. The clinical manifestations varied, with the morphological appearances of the rash resembling those of eczema, lupus erythematosus, lichen planus, and a highly characteristic toxic erythematous psoriasiform eruption. Persistent ocular damage was a feature in three cases.
D000368:Aged; D001706:Biopsy; D003320:Corneal Ulcer / Q000139:chemically induced; D003875:Drug Eruptions / Q000209:etiology*; D004483:Ectropion / Q000139:chemically induced; D005148:Facial Dermatoses / Q000139:chemically induced; D005260:Female; D005455:Fluorescent Antibody Technique; D006229:Hand Dermatoses / Q000139:chemically induced; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007634:Keratitis / Q000139:chemically induced; D007868:Leg Dermatoses / Q000139:chemically induced; D008047:Lip Diseases / Q000139:chemically induced; D008297:Male; D008875:Middle Aged; D010490:Pericardial Effusion / Q000139:chemically induced; D010996:Pleural Effusion / Q000139:chemically induced; D011217:Practolol / Q000009:adverse effects*; D011565:Psoriasis / Q000139:chemically induced; D012867:Skin / Q000473:pathology; D013280:Stomatitis / Q000139:chemically induced
D007136:Immunoglobulins; D011217:Practolol