title: X-ray-diffraction patterns from chondroitin 4-sulphate, dermatan sulphate and heparan sulphate.
abstract: Ordered conformations from the sodium salts of chondroitin 4-sulphate, dermatan sulphate and heparan sulphate were observed by X-ray diffraction. Chondroitin 4-sulphate shows similar threefold helical character to that previously reported for chondroitin 6-sulphate and hyaluronates. Dermatan sulphate forms an eightfold helix with an axial rise per disaccharide of 0.93nm, which favours the l-iduronic acid moiety in the normal C1 chair form. The layer-line spacing and axial projection in heparan sulphate of 1.86nm favours a tetrasaccharide repeat with glycosidic linkages alternating beta-d-(1-->4) and alpha-d-(1-->4).
mesh_terms: D000818:Animals; D002417:Cattle; D002807:Chondroitin; D004187:Disaccharides; D006025:Glycosaminoglycans; D006820:Hyaluronic Acid; D008961:Models, Structural; D014961:X-Ray Diffraction
chemical_list: D004187:Disaccharides; D006025:Glycosaminoglycans; D006820:Hyaluronic Acid; D002807:Chondroitin