Some factors affecting the conversion of pyrrolizidine alkaloids to N-oxides and to pyrrolic derivatives in vitro.
D000588:Amines / Q000494:pharmacology; D000818:Animals; D001386:Azides / Q000494:pharmacology; D002248:Carbon Monoxide / Q000494:pharmacology; D002729:Chloromercuribenzoates / Q000494:pharmacology; D003486:Cyanides / Q000494:pharmacology; D004229:Dithiothreitol / Q000494:pharmacology; D007461:Iodoacetates / Q000494:pharmacology; D007700:Kinetics; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D009536:Niacinamide / Q000494:pharmacology; D010087:Oxides / Q000378:metabolism*; D010100:Oxygen / Q000494:pharmacology; D010634:Phenobarbital / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011758:Pyrroles / Q000378:metabolism*; D011763:Pyrrolizidine Alkaloids / Q000378:metabolism*; D051381:Rats; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D013997:Time Factors
D000588:Amines; D001386:Azides; D002729:Chloromercuribenzoates; D003486:Cyanides; D007461:Iodoacetates; D010087:Oxides; D011758:Pyrroles; D011763:Pyrrolizidine Alkaloids; D013438:Sulfhydryl Compounds; D009536:Niacinamide; D008748:Methylcholanthrene; D002248:Carbon Monoxide; D011335:Proadifen; D010100:Oxygen; D004229:Dithiothreitol; D010634:Phenobarbital