title: Vitamin E, selenium and methionine supplementation of dystrophogenic diets for pigs.
abstract: Forty-eight weanling S.P.F. Yorshire pigs were used to study the influence of supplemental vitamin E (25 IU per kg of diet) selenium (0.5 ppm in diet) and methionine (0.1% in diet) on the incidence of hepatosis dietetica and mulberry heart disease when fed a torula yeast-corn diet. Vitamin E and/or selenium increased pig survival. Supplemental selenium resulted in increased liver selenium concentrations. No hepatosis dietetica was observed in any of the pigs. The addition of vitamin E and/or selenium at the levels used did not reduce the frequency of myocardial lesions; however, they prevented skeletal muscular dystrophy and exudative diathesis. The myocardial lesions were less severe in supplemented pigs compared with unsupplemented controls.
mesh_terms: D000818:Animals; D003454:Cryptococcus; D004032:Diet; D004198:Disease Susceptibility; D005122:Exudates and Transudates; D005260:Female; D006331:Heart Diseases / Q000517:prevention & control / Q000662:veterinary*; D008107:Liver Diseases / Q000517:prevention & control / Q000662:veterinary*; D008297:Male; D008715:Methionine / Q000494:pharmacology*; D009135:Muscular Diseases / Q000517:prevention & control / Q000662:veterinary; D012643:Selenium / Q000032:analysis / Q000494:pharmacology*; D013025:Glycine max; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014652:Vascular Diseases / Q000517:prevention & control / Q000662:veterinary; D014810:Vitamin E / Q000032:analysis / Q000494:pharmacology*; D015002:Yeast, Dried; D003313:Zea mays
chemical_list: D014810:Vitamin E; D008715:Methionine; D012643:Selenium