New synthetic steroids which inhibit rat gonadal steroidogenic enzymes both in vitro and in vivo.
D000315:Adrenalectomy; D000731:Androstanes / Q000494:pharmacology*; D000818:Animals; D002247:Carbon Isotopes; D002369:Castration; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D003687:Dehydroepiandrosterone / Q000378:metabolism; D005260:Female; D006908:Hydroxyprogesterones / Q000378:metabolism; D006913:Hydroxysteroid Dehydrogenases / Q000037:antagonists & inhibitors*; D066298:In Vitro Techniques; D008190:Lyases / Q000037:antagonists & inhibitors*; D008297:Male; D013058:Mass Spectrometry; D008861:Microsomes / Q000201:enzymology; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors*; D010053:Ovary / Q000201:enzymology; D011278:Pregnanes / Q000494:pharmacology*; D011284:Pregnenolone / Q000378:metabolism; D011374:Progesterone / Q000378:metabolism; D051381:Rats; D013737:Testis / Q000201:enzymology; D014316:Tritium
D000731:Androstanes; D002247:Carbon Isotopes; D006908:Hydroxyprogesterones; D011278:Pregnanes; D014316:Tritium; D003687:Dehydroepiandrosterone; D011374:Progesterone; D011284:Pregnenolone; D006899:Mixed Function Oxygenases; D006913:Hydroxysteroid Dehydrogenases; D008190:Lyases