Vesicular stomatitis virus replication in human leukocyte cultures: enhancement by phytohemagglutinin.
The replication of vesicular stomatitis virus in human leukocyte cultures shows that virus yields can be enhanced 6-to 180-fold by treating the leukocyte cultures with phytohemagglutinin prior to virus inoculation. Data suggest that a substance is produced in phytohemagglutinin-treated leukocyte cultures which is capable, on transfer to fresh leukocytes, of inducing blast cell formation and enhancing virus replication.
D000328:Adult; D006801:Humans; D037102:Lectins / Q000494:pharmacology*; D007962:Leukocytes; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects*; D014776:Virus Cultivation
D037102:Lectins