Overgrowth stimulating factor released from Rous sarcoma cells.
An assay is described for a nonzviral factor from the medium of Rous sarcoma cells which stimulates rapid and sustained cellular overgrawth in crowded chick embryo cultures. The factor is nondialyzable and thermnolabile and is released in large amounts several days after the first visible transformation of newly infected chick embryo cells.
D000818:Animals; D002642:Chick Embryo / Q000166:cytology; D003470:Culture Media; D046508:Culture Techniques; D004247:DNA / Q000096:biosynthesis*; D008938:Mitosis; D001357:Sarcoma, Avian; D013268:Stimulation, Chemical; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D003470:Culture Media; D014316:Tritium; D004247:DNA; D013936:Thymidine