Mycotoxicosis: toxic fungi in tobaccos.
Cigarette, cigar, and pipe tobaccos contain Alternaria spores and dematiaceous mycelia, with cigarette tobaccos being more heavily laden. A smoke aerosol generated from hay on which the fungus had been cultured caused, among other pathologic changes, pulmonary emphysema in mice.
D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000209:etiology*; D000336:Aerosols; D000818:Animals; D001230:Aspergillus; D066298:In Vitro Techniques; D051379:Mice; D003904:Mitosporic Fungi; D009374:Neoplasms, Experimental / Q000209:etiology*; D010947:Plants, Toxic; D011656:Pulmonary Emphysema / Q000209:etiology*; D012907:Smoking; D014026:Nicotiana; D014118:Toxins, Biological / Q000633:toxicity*
D000336:Aerosols; D014118:Toxins, Biological