Acute hepatitis due to Herpes simplex virus in an adult.
A case is described of herpetic hepatitis in a pregnant woman with primary herpetic stomatitis. Intranuclear inclusion bodies and virus particles were found in hepatocytes, and herpes virus was isolated from a liver biopsy and from oral swabs but not from blood. From rising titres of neutralizing and complement-fixing antibody it is concluded that the oral infection was a primary one. Factors predisposing to the hepatitis are discussed.
D000328:Adult; D003168:Complement Fixation Tests; D005260:Female; D006506:Hepatitis A / Q000209:etiology*; D006566:Herpesviridae Infections; D006801:Humans; D008099:Liver / Q000166:cytology* / Q000382:microbiology; D009500:Neutralization Tests; D011247:Pregnancy; D018139:Simplexvirus / Q000302:isolation & purification*; D013280:Stomatitis / Q000150:complications