Inhibition of thymidylate kinase and DNA polymerase by the periodate oxidation product of beta-D-ribosyl-6-methylthiopurine.
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology* / Q000378:metabolism; D004254:DNA Nucleotidyltransferases / Q000037:antagonists & inhibitors*; D004261:DNA Replication; D004273:DNA, Neoplasm / Q000378:metabolism*; D005260:Female; D066298:In Vitro Techniques; D051379:Mice; D010084:Oxidation-Reduction; D010504:Periodic Acid / Q000494:pharmacology*; D011687:Purines / Q000494:pharmacology*; D013936:Thymidine / Q000378:metabolism; D013937:Thymidine Kinase / Q000037:antagonists & inhibitors*; D013997:Time Factors; D014316:Tritium
D004273:DNA, Neoplasm; D011687:Purines; D014316:Tritium; D010504:Periodic Acid; D013937:Thymidine Kinase; D004254:DNA Nucleotidyltransferases; D013936:Thymidine