Intestinal calcium absorption: nature of defect in chronic renal disease.
When compared to that of normal animals, calcium-binding protein activity of duodenal mucosa obtained from uremic rats was decreased. There was no change in this activity after vitamin D(3), therapy. In contrast, prior treatment with 25-hydroxycholecalcijerol resulted in increased transport of calcium-45 and calcium-binding protein activity in the intestine.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002762:Cholecalciferol / Q000494:pharmacology / Q000627:therapeutic use; D002908:Chronic Disease; D004386:Duodenum; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism; D008297:Male; D011485:Protein Binding; D051381:Rats; D013268:Stimulation, Chemical; D014511:Uremia / Q000188:drug therapy / Q000378:metabolism*
D002762:Cholecalciferol; D002118:Calcium