The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity.
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology / Q000633:toxicity*; D003920:Diabetes Mellitus / Q000139:chemically induced* / Q000517:prevention & control; D004336:Drug Antagonism; D007515:Islets of Langerhans / Q000473:pathology; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D051379:Mice; D009243:NAD / Q000378:metabolism; D009536:Niacinamide / Q000494:pharmacology / Q000627:therapeutic use*
D000903:Antibiotics, Antineoplastic; D009243:NAD; D009536:Niacinamide