Adenovirus endocarditis in mice.
Viral endocarditis developed in 24 percent of 50 newborn mice 6 to 8 days after intraperitoneal inoculation with murine adenovirus. Typical adenovirus intranuclear inclusions were seen in heart-valve lesions, and high titers of virus were recovered from heart tissue. Furthermore, adenovirions were directly visualized by electron microscopy within endothelial cells and fibroblasts of the heart valves.
D000257:Adenoviridae Infections / Q000473:pathology*; D000818:Animals; D000831:Animals, Newborn; D001021:Aortic Valve / Q000473:pathology; D004696:Endocarditis / Q000473:pathology*; D051379:Mice; D008854:Microscopy, Electron