Effectiveness of acetic acid, betadine, amphyll, polymyxin B, colistin, and gentamicin against Pseudomonas aeruginosa.
The in vitro effectiveness of three germicides and three chemotherapeutic drugs against hospital-isolated strains of Pseudomonas aeruginosa was determined. Solutions of 1% acetic acid, 0.5% Amphyll, and 0.1% Betadine were bactericidal for six strains tested within 15 min at room temperature. Over a 3-year period at the Albany Medical Center Hospital, the percentages of strains of P. aeruginosa susceptible to polymyxin B, colistin, and gentamicin did not increase. During this 3-year period, polymyxin B and colistin were administered at the hospital but gentamicin was not.
D000085:Acetates / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003091:Colistin / Q000494:pharmacology; D004202:Disinfectants / Q000494:pharmacology*; D005839:Gentamicins / Q000494:pharmacology; D007455:Iodine / Q000494:pharmacology*; D011113:Polymyxins / Q000494:pharmacology; D011205:Povidone / Q000494:pharmacology*; D011206:Povidone-Iodine / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects*
D000085:Acetates; D000900:Anti-Bacterial Agents; D004202:Disinfectants; D005839:Gentamicins; D011113:Polymyxins; D011206:Povidone-Iodine; D007455:Iodine; D011205:Povidone; D003091:Colistin