Parathyroid hormone production in vitro by human parathyroid cells transformed by Simian virus 40.
Cells froma human parathyroid adenoma were infected with simian virus 40 and maintained through 13 subcultures in monolayer tissue culture. For more than 9 months, these "transformed" cells contimed to produce parathyroid hormone which was identified by radioimmunoassay and density-gradient ultra centrifugation.
D000236:Adenoma; D002454:Cell Differentiation; D002499:Centrifugation, Density Gradient; D046508:Culture Techniques; D006801:Humans; D010281:Parathyroid Hormone / Q000096:biosynthesis*; D010282:Parathyroid Neoplasms / Q000378:metabolism*; D011863:Radioimmunoassay; D013539:Simian virus 40
D010281:Parathyroid Hormone