title: Comparative study of seven picornaviruses of man.
abstract: Jamison, Richard M. (Baylor University College of Medicine, Houston, Tex.), and Heather D. Mayor. Comparative study of seven picornaviruses of man. J. Bacteriol. 91:1971-1976. 1966.-The buoyant densities in CsCl and potassium tartrate of seven acid-resistant picornaviruses of man were determined. The viruses studied were found to be a relatively homogeneous group. Buoyant densities ranged from 1.32 to 1.35 g/cc in CsCl and 1.21 to 1.23 g/cc in potassium tartrate. The buoyant density of each virus did not vary by more than 0.01 g/cc. The host cell of origin and passage level did not influence the buoyant density of the virions. However, measurements of the diameters of purified virions by a standard method have shown that there are considerable size variations among these picornaviruses. The diameters ranged from 18 to 25 mmu. Echovirus 19 and poliovirus 1 were significantly larger (mean diameter, 23.5 mmu) than echoviruses 4, 6, 16, and 23, and coxsackievirus B2 (mean diameter, 21.0 mmu).
mesh_terms: D004770:Enterovirus; D029822:Enterovirus B, Human; D006801:Humans; D066298:In Vitro Techniques; D008854:Microscopy, Electron; D017955:Poliovirus; D014461:Ultracentrifugation