Heterogeneity of templae RNA in adrenal glands.
Template RNA in adrenal glands appears to be heterogeneous in stability. The RNA that regulates synthesis of a large fraction of adrenal protein has a turnover time of 4 hours or less. The remainder of adrenal-protein synthesis, including synthesis of protein that mediates the rapid steroidogenic response to ACTH, depends on RNA with considerably greater stability.
D000311:Adrenal Glands / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology*; D000818:Animals; D003345:Corticosterone / Q000378:metabolism*; D003609:Dactinomycin / Q000494:pharmacology*; D005472:Fluorouracil / Q000494:pharmacology*; D007016:Hypophysectomy; D012313:RNA / Q000096:biosynthesis* / Q000378:metabolism*; D051381:Rats; D014529:Uridine / Q000378:metabolism*
D003609:Dactinomycin; D012313:RNA; D000324:Adrenocorticotropic Hormone; D005472:Fluorouracil; D003345:Corticosterone; D014529:Uridine