The synthesis of 5-fluorouridine 5'-phosphate by a pyrimidine phosphoribosyltransferase of mammalian origin. I. Some properties of the enzyme from P1534J mouse leukemic cells.
D000818:Animals; D002247:Carbon Isotopes; D002474:Cell-Free System; D002854:Chromatography, Paper; D003035:Cobalt; D046508:Culture Techniques; D003864:Depression, Chemical; D011756:Diphosphates / Q000378:metabolism / Q000494:pharmacology; D005472:Fluorouracil / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D007942:Leukemia, Experimental / Q000188:drug therapy / Q000201:enzymology*; D008345:Manganese; D051379:Mice; D009711:Nucleotides / Q000096:biosynthesis* / Q000627:therapeutic use; D010428:Pentosephosphates; D011687:Purines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology; D013268:Stimulation, Chemical; D014166:Transferases / Q000037:antagonists & inhibitors / Q000378:metabolism*
D002247:Carbon Isotopes; D011756:Diphosphates; D009711:Nucleotides; D010428:Pentosephosphates; D011687:Purines; D011743:Pyrimidines; D003035:Cobalt; D008345:Manganese; D014166:Transferases; D005472:Fluorouracil