Congenital adrenal hyperplasia secondary to 17-hydroxylase deficiency. Two sisters with amenorrhea, hypokalemia, hypertension, and cystic ovaries.
D000293:Adolescent; D000311:Adrenal Glands / Q000378:metabolism; D000312:Adrenal Hyperplasia, Congenital / Q000235:genetics*; D000324:Adrenocorticotropic Hormone / Q000096:biosynthesis; D000568:Amenorrhea / Q000209:etiology*; D003345:Corticosterone / Q000096:biosynthesis; D003900:Desoxycorticosterone / Q000096:biosynthesis; D003907:Dexamethasone / Q000627:therapeutic use; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D005640:Follicle Stimulating Hormone / Q000096:biosynthesis; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D007008:Hypokalemia / Q000209:etiology*; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D010048:Ovarian Cysts / Q000235:genetics*
D004967:Estrogens; D003900:Desoxycorticosterone; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone; D005640:Follicle Stimulating Hormone; D006899:Mixed Function Oxygenases; D003345:Corticosterone