Cell proliferation: enhancement by extracts from cell surfaces of polyoma-virus-transformed cells.
Dispersion of confluent monolayers of BHK21 cells with ethylenediaminetetraacetate yields a material that inhibits cell proliferation, whereas identical extraction of polyoma-virus-transformed cells provides material which enhances cellular proliferation. The material was partially characterized.
D000818:Animals; D002471:Cell Transformation, Neoplastic; D002850:Chromatography, Gel; D003124:Colorimetry; D003260:Contact Inhibition; D006224:Cricetinae; D046508:Culture Techniques; D003956:Dialysis; D004492:Edetic Acid; D006025:Glycosaminoglycans / Q000032:analysis / Q000494:pharmacology*; D007668:Kidney / Q000166:cytology; D008970:Molecular Weight; D009374:Neoplasms, Experimental; D011120:Polyomavirus; D013499:Surface Properties; D014020:Tissue Extracts / Q000494:pharmacology; D014461:Ultracentrifugation
D006025:Glycosaminoglycans; D014020:Tissue Extracts; D004492:Edetic Acid