title: A rat-tissue aminotransferase acting on L-tyrosine O-sulphate.
abstract: 1. Rat tissues have been shown to possess an aminotransferase that is active towards l-tyrosine O-sulphate and dependent on 2-oxoglutarate and pyridoxal phosphate. 2. Kidney, liver and pancreas have the greatest activity and the enzyme is localized mainly in the mitochondrial fraction in the liver and kidney cell. 3. The enzyme was shown to be distinct from l-tyrosine-2-oxoglutarate aminotransferase but its true identity was not established. 4. A procedure for the assay of the enzyme in crude tissue preparations was developed.
mesh_terms: D000818:Animals; D003576:Electron Transport Complex IV / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology; D066298:In Vitro Techniques; D007656:Ketoglutaric Acids; D007668:Kidney / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D010179:Pancreas / Q000201:enzymology; D011732:Pyridoxal Phosphate; D051381:Rats; D013347:Subcellular Fractions / Q000378:metabolism; D013431:Sulfates / Q000378:metabolism*; D000637:Transaminases / Q000378:metabolism*; D014443:Tyrosine / Q000378:metabolism*
chemical_list: D007656:Ketoglutaric Acids; D013431:Sulfates; D014443:Tyrosine; D011732:Pyridoxal Phosphate; D007770:L-Lactate Dehydrogenase; D003576:Electron Transport Complex IV; D000637:Transaminases; D006854:Hydrocortisone