Eosinophilic response in glioblastoma tissue culture after addition of autologous lymphocytes.
In experiments designed for the study of interactions in vitro between the cells of glioblastoma multiforme and lymphocytes from the same donor, a marked eosinophilic response was noted in three out of six cases. This was an entirely unexpected finding since few, if any, eosinophils survive in tissue cultures. These cells incorporated (3)H-cytidine and (3)H-leucine 72 hours after the cultures had been established, an indication that they were metabolically active.
D001345:Autoradiography; D046508:Culture Techniques; D004804:Eosinophils; D005909:Glioblastoma / Q000473:pathology*; D006801:Humans; D007930:Leucine / Q000378:metabolism; D008214:Lymphocytes; D009705:Nucleosides / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis; D014316:Tritium
D009705:Nucleosides; D014316:Tritium; D012313:RNA; D007930:Leucine