Endocrine control of adrenal progesterone secretion in the ovariectomized rat.
In the ovariectomized rat, the adrenal gland secretes progesterone. Adrenocorticotropin treatment elevates concentrations of this steroid in plasma, and inhibitors of adrenocorticotropin or progesterone biosynthesis lower the concentration. Adrenocorticotropin controls progesterone secretion by the adrenal but not by the ovary. Adrenal progesterone and its mode of control may have important influences on reproductive processes.
D000311:Adrenal Glands / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology / Q000502:physiology*; D000616:Aminoglutethimide / Q000494:pharmacology; D000704:Analysis of Variance; D000818:Animals; D002369:Castration; D003907:Dexamethasone / Q000494:pharmacology; D005260:Female; D010053:Ovary / Q000601:surgery; D011374:Progesterone / Q000097:blood / Q000378:metabolism*; D051381:Rats; D012098:Reproduction
D000616:Aminoglutethimide; D011374:Progesterone; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone