Simian virus 40-induced T and tumor antigens.
Antigen extracts from simian virus 40 (SV40) transplanted hamster tumors were studied by rate-zonal centrifugation. Three species or molecular forms of antigen were demonstrated. The major antigen component corresponded to a molecular weight of 65,000 to 75,000, and two larger species were detectable in smaller quantities. Similar studies were carried out on SV40 virus-induced T antigen from BSC-1 cells. Three antigen components were again detected. Quantitative differences in the expression of "T" and tumor antigen species were reproducibly found.
D000818:Animals; D000941:Antigens / Q000145:classification*; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000276:immunology*; D002499:Centrifugation, Density Gradient; D003168:Complement Fixation Tests; D006224:Cricetinae; D000882:Haplorhini; D007668:Kidney; D008970:Molecular Weight; D009368:Neoplasm Transplantation; D013539:Simian virus 40 / Q000276:immunology*; D014181:Transplantation Immunology
D000941:Antigens