Biophysical study of the mode of action of the tetracycline antibiotics. Inhibition of metalloflavoenzyme NADH cytochrome oxidoreductase.
D001419:Bacteria / Q000187:drug effects; D002751:Chlortetracycline; D003580:Cytochromes; D004798:Enzymes; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007502:Iron Chelating Agents; D009243:NAD; D010088:Oxidoreductases; D013053:Spectrophotometry; D013752:Tetracycline / Q000494:pharmacology*
D003580:Cytochromes; D004798:Enzymes; D007502:Iron Chelating Agents; D009243:NAD; D010088:Oxidoreductases; D013752:Tetracycline; D002751:Chlortetracycline