Bronchopneumonia with serious sequelae in children with evidence of adenovirus type 21 infection.
Twenty-five cases of severe pneumonitis occurring among children aged 3 to 18 months were observed in Auckland, New Zealand, in 1965. An apparent relationship was established between a uniform disease picture and recovery of adenovirus type 21. Two died, and of the survivors 60% had permanent lung damage, probably resulting from obliterative bronchiolitis. Twenty per cent. were left with proved bronchiectasis. The possible relationships of adenovirus pneumonia to malnutrition or a genetic factor on the one hand and to the development of bronchiectasis on the other are discussed.
D000257:Adenoviridae Infections / Q000150:complications*; D001987:Bronchiectasis / Q000209:etiology; D001990:Bronchiolitis, Viral / Q000150:complications; D001996:Bronchopneumonia / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D003168:Complement Fixation Tests; D005260:Female; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000209:etiology; D008297:Male; D009520:New Zealand; D009748:Nutrition Disorders / Q000150:complications; D011859:Radiography; D044465:White People