Nasal mucosal absorption of tetracosactrin as indicated by rise in plasma fluorogenic corticosteroids.
Tetracosactrin has been administered to six healthy dexamethasone-suppressed subjects by nasal insufflation. The pronounced increase of the plasma fluorogenic corticosteroids suggests that the peptide is well absorbed by this route.
D000042:Absorption; D000305:Adrenal Cortex Hormones / Q000097:blood*; D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage* / Q000378:metabolism; D003907:Dexamethasone; D006801:Humans; D009297:Nasal Mucosa / Q000378:metabolism*; D010455:Peptides / Q000008:administration & dosage / Q000378:metabolism
D000305:Adrenal Cortex Hormones; D010455:Peptides; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone