ACTH and decubitus ulceration: an experimental study.
1. Ulcers due to neurectomy with excision of the sciatic nerve are more severe than those due to tenotomy and can be inhibited by a single dose of ACTH.2. Timing and mode of administration of ACTH to prevent decubitus ulceration is critical and depends on its ability to prevent the separation of endothelial cells.
D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D003714:Denervation; D004848:Epithelium; D051379:Mice; D008854:Microscopy, Electron; D003668:Pressure Ulcer / Q000188:drug therapy*; D012584:Sciatic Nerve; D012867:Skin / Q000098:blood supply; D013710:Tendons; D013997:Time Factors
D000324:Adrenocorticotropic Hormone