Antibiotic activity in the presence of agar.
Agar has been shown to interfere with the activity of some antibiotics against Staphylococcus aureus. This interference has been observed as an increase in the minimal inhibitory concentration and in the diameter of the zone of inhibition. Purifying the agar with water extractions substantially reduced this adverse effect.
D000362:Agar / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002751:Chlortetracycline / Q000494:pharmacology; D007612:Kanamycin / Q000494:pharmacology; D009355:Neomycin / Q000494:pharmacology; D009675:Novobiocin / Q000494:pharmacology; D010118:Oxytetracycline / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology; D011113:Polymyxins / Q000494:pharmacology; D013210:Staphylococcus / Q000187:drug effects*; D013307:Streptomycin / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D010406:Penicillins; D011113:Polymyxins; D009675:Novobiocin; D007612:Kanamycin; D014640:Vancomycin; D000362:Agar; D013752:Tetracycline; D009355:Neomycin; D002751:Chlortetracycline; D010118:Oxytetracycline; D013307:Streptomycin