title: Aminoglutethimide (Elipten-Ciba) as an inhibitor of adrenal steroidogenesis: mechanism of action and therapeutic trial.
mesh_terms: D000305:Adrenal Cortex Hormones / Q000096:biosynthesis*; D000311:Adrenal Glands / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D000324:Adrenocorticotropic Hormone; D000328:Adult; D000616:Aminoglutethimide / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology* / Q000627:therapeutic use; D001943:Breast Neoplasms; D002648:Child; D002784:Cholesterol / Q000378:metabolism; D002986:Clinical Trials as Topic; D003480:Cushing Syndrome / Q000188:drug therapy; D057487:Enzyme Therapy; D004798:Enzymes / Q000494:pharmacology; D004832:Epilepsy, Absence / Q000188:drug therapy; D005260:Female; D006801:Humans; D008190:Lyases / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011284:Pregnenolone / Q000096:biosynthesis; D051381:Rats
chemical_list: D000305:Adrenal Cortex Hormones; D000927:Anticonvulsants; D004798:Enzymes; D000616:Aminoglutethimide; D011284:Pregnenolone; D000324:Adrenocorticotropic Hormone; D002784:Cholesterol; D008190:Lyases