Hypernatremia due to hypodipsia and elevated threshold for vasopressin release. Effects of treatment with hydrochlorothiazide, chlorpropamide and tolbutamide.
D002747:Chlorpropamide / Q000627:therapeutic use*; D003404:Creatinine / Q000652:urine; D000242:Cyclic AMP / Q000378:metabolism; D003681:Dehydration; D004231:Diuresis; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use*; D006955:Hypernatremia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology* / Q000652:urine; D007031:Hypothalamus / Q000503:physiopathology; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D008875:Middle Aged; D009994:Osmolar Concentration; D012964:Sodium / Q000097:blood / Q000652:urine; D013894:Thirst; D014044:Tolbutamide / Q000627:therapeutic use*; D014667:Vasopressins / Q000378:metabolism*; D014867:Water / Q000378:metabolism; D014882:Water-Electrolyte Balance
D007328:Insulin; D014867:Water; D006852:Hydrochlorothiazide; D014667:Vasopressins; D014044:Tolbutamide; D012964:Sodium; D003404:Creatinine; D000242:Cyclic AMP; D002747:Chlorpropamide