Further studies on the relationship of the stimulatory effects of phenobarbital and 3,4-benzpyrene on hepatic heme synthesis to their effects on hepatic microsomal drug oxidations.
D000818:Animals; D001580:Benzopyrenes / Q000494:pharmacology*; D002247:Carbon Isotopes; D003580:Cytochromes / Q000032:analysis / Q000378:metabolism; D004789:Enzyme Activation; D006418:Heme / Q000032:analysis / Q000096:biosynthesis*; D007982:Levulinic Acids; D008025:Ligases / Q000378:metabolism; D008099:Liver / Q000032:analysis / Q000378:metabolism*; D008297:Male; D008862:Microsomes, Liver / Q000032:analysis / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D009243:NAD; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology*; D011506:Proteins / Q000032:analysis; D051381:Rats; D013268:Stimulation, Chemical
D001580:Benzopyrenes; D002247:Carbon Isotopes; D003580:Cytochromes; D007982:Levulinic Acids; D011506:Proteins; D009243:NAD; D006418:Heme; D010088:Oxidoreductases; D008025:Ligases; D010634:Phenobarbital