Studies on the site of action of o,p'-DDD in the dog adrenal cortex. 1. Inhibition of ACTH-mediated pregnenolone synthesis.
D000311:Adrenal Glands / Q000166:cytology / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000037:antagonists & inhibitors*; D000818:Animals; D002087:Butyrates / Q000494:pharmacology; D002855:Chromatography, Thin Layer; D003345:Corticosterone / Q000096:biosynthesis; D000242:Cyclic AMP / Q000494:pharmacology; D003864:Depression, Chemical; D003632:Dichlorodiphenyldichloroethane / Q000494:pharmacology*; D004285:Dogs; D006854:Hydrocortisone / Q000096:biosynthesis; D008297:Male; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D011284:Pregnenolone / Q000096:biosynthesis* / Q000378:metabolism; D014316:Tritium; D014466:Ultraviolet Rays
D002087:Butyrates; D014316:Tritium; D011284:Pregnenolone; D000324:Adrenocorticotropic Hormone; D000242:Cyclic AMP; D003632:Dichlorodiphenyldichloroethane; D003345:Corticosterone; D006854:Hydrocortisone