Effects in vitro of 2-aminofluorene or electrophilic agents on hepatic microsomal N- and C-oxygenation of aromatic amines.
D000081:Acetamides / Q000494:pharmacology; D000085:Acetates / Q000494:pharmacology; D000588:Amines / Q000494:pharmacology; D000814:Aniline Compounds / Q000378:metabolism; D000818:Animals; D003640:Dealkylation; D004357:Drug Synergism; D004579:Electron Transport / Q000187:drug effects; D005449:Fluorenes / Q000494:pharmacology*; D005954:Glucosephosphate Dehydrogenase; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008297:Male; D008628:Mercury / Q000494:pharmacology; D008745:Methylation; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D009942:Organometallic Compounds / Q000494:pharmacology; D010084:Oxidation-Reduction; D010100:Oxygen; D051381:Rats; D011919:Rats, Inbred Strains; D012822:Silicon Dioxide / Q000494:pharmacology; D013045:Species Specificity; D013997:Time Factors
D000081:Acetamides; D000085:Acetates; D000588:Amines; D000814:Aniline Compounds; D005449:Fluorenes; D009942:Organometallic Compounds; D012822:Silicon Dioxide; D005954:Glucosephosphate Dehydrogenase; D008628:Mercury; D010100:Oxygen