title: [3H]adenosine triphosphate: release during stimulation of enteric nerves.
abstract: The isolated taenia coli of the guinea pig takes up tritiated adenosine, adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate, in preference to tritiated inosine and adenine. After uptake, [(3)H]adenosine is converted and retained primarily as [(3)H]adenosine triphosphate. Tritium is released from taenia coli treated with [(3)H]adenosine upon activation of the nonadrenergic inhibitory nerves. These results are consistent with the previous evidence that adenosine triphosphate may be the transmitter from the nerves.
mesh_terms: D000227:Adenine Nucleotides / Q000032:analysis* / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000096:biosynthesis / Q000378:metabolism* / Q000502:physiology; D000818:Animals; D003106:Colon / Q000187:drug effects / Q000294:innervation / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism; D004558:Electric Stimulation; D006168:Guinea Pigs; D009197:Myenteric Plexus / Q000502:physiology*; D009705:Nucleosides / Q000494:pharmacology; D013997:Time Factors; D014316:Tritium / Q000032:analysis*
chemical_list: D000227:Adenine Nucleotides; D009705:Nucleosides; D014316:Tritium; D000255:Adenosine Triphosphate; D000242:Cyclic AMP