Mechanism of ethanol suppression of gluconeogenesis. Inhibition of phosphoenolpyruvate synthesis from glutamate and alpha-ketaglutarate.
D000085:Acetates / Q000096:biosynthesis; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D002952:Citric Acid Cycle / Q000187:drug effects*; D003956:Dialysis; D004140:Dinitrophenols / Q000494:pharmacology; D000431:Ethanol / Q000494:pharmacology*; D005943:Gluconeogenesis / Q000187:drug effects; D005971:Glutamates / Q000378:metabolism*; D006885:Hydroxybutyrates; D007656:Ketoglutaric Acids / Q000378:metabolism*; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism; D009243:NAD / Q000378:metabolism; D010101:Oxygen Consumption; D011773:Pyruvates / Q000096:biosynthesis*; D011817:Rabbits
D000085:Acetates; D000596:Amino Acids; D004140:Dinitrophenols; D005971:Glutamates; D006885:Hydroxybutyrates; D007656:Ketoglutaric Acids; D011773:Pyruvates; D009243:NAD; D000431:Ethanol