Herpesvirus hominis type 2 infections in rabbits: effect of prior immunization with attenuated Mycobacterium bovis (BCG) cells.
Angora, New Zealand, and Dutch-belted rabbits were tested for their susceptibility to graded doses of Herpesvirus hominis type 2 administered by vaginal instillation, intracorneal injection, and scarification of the cornea. Central nervous system involvement and death occurred after infection by the various routes employed. Prior immunization of Dutch-belted and New Zealand rabbits with viable Mycobacterium bovis (BCG) cells injected intravenously provided protection against subsequent infections with type 2 virus.
D000818:Animals; D004660:Encephalitis / Q000209:etiology; D005260:Female; D006566:Herpesviridae Infections / Q000150:complications / Q000276:immunology* / Q000401:mortality; D007114:Immunization; D007275:Injections, Intravenous; D007928:Lethal Dose 50; D009163:Mycobacterium bovis / Q000276:immunology*; D011817:Rabbits; D018139:Simplexvirus / Q000276:immunology* / Q000472:pathogenicity; D014611:Vaccination; D014613:Vaccines, Attenuated; D014621:Vagina
D014613:Vaccines, Attenuated