Effect of polycations on sensitivity of BALD-3T3 cells to murine leukemia and sarcoma virus infectivity.
Polybrene or diethylaminoethyl dextran, when added with murine leukemia or sarcoma virus inocula, significantly increased virus infectivity of BALB/3T3 cells. Residual polycation concentrations were nontoxic.
D000818:Animals; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured / Q000187:drug effects*; D003470:Culture Media; D003588:Cytopathogenic Effect, Viral; D003911:Dextrans / Q000494:pharmacology* / Q000633:toxicity; D017988:Gammaretrovirus / Q000472:pathogenicity*; D009052:Leukemia Virus, Murine / Q000472:pathogenicity*; D051379:Mice; D008815:Mice, Inbred Strains; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*
D003470:Culture Media; D003911:Dextrans; D000644:Quaternary Ammonium Compounds