Interferon and cell division. I. Inhibition of the multiplication of mouse leukemia L 1210 cells in vitro by interferon preparations.
Mouse interferon preparations inhibited the multiplication of mouse leukemia L 1210 cells in stationary suspension cultures. The degree of inhibition was found to correlate with the antiviral titer of the interferon preparations. The factor(s) responsible for inhibition of L 1210 cell multiplication could not be dissociated from interferon by standard physicochemical means.
D000818:Animals; D002455:Cell Division / Q000187:drug effects*; D002460:Cell Line / Q000187:drug effects; D046508:Culture Techniques; D006358:Hot Temperature; D006801:Humans; D007106:Immune Sera / Q000494:pharmacology; D007372:Interferons / Q000302:isolation & purification / Q000494:pharmacology*; D007939:Leukemia L1210; D051379:Mice; D010504:Periodic Acid / Q000494:pharmacology; D014357:Trypsin / Q000494:pharmacology; D014721:Vesicular stomatitis Indiana virus
D007106:Immune Sera; D010504:Periodic Acid; D007372:Interferons; D014357:Trypsin