Metabolic controls in precancerous liver. II. Loss of feedback control of cholesterol synthesis, measured repeatedly in vivo, during treatment with the carcinogens N-2-fluorenylacetamide and aflatoxin.
D000081:Acetamides / Q000494:pharmacology*; D000348:Aflatoxins / Q000494:pharmacology*; D000818:Animals; D002273:Carcinogens / Q000494:pharmacology*; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced; D002784:Cholesterol / Q000096:biosynthesis*; D004032:Diet; D005246:Feedback; D005449:Fluorenes / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008113:Liver Neoplasms / Q000139:chemically induced; D008297:Male; D011230:Precancerous Conditions / Q000378:metabolism*; D051381:Rats
D000081:Acetamides; D000348:Aflatoxins; D002273:Carcinogens; D005449:Fluorenes; D002784:Cholesterol