Stimulation of DNA-dependent RNA synthesis by a protein associated with ribosomes.
A protein factor partially purified from ribosomes of Escherichia coli RC(rel) cells starved for an amino acid markedly stimulates DNA-dependent RNA synthesis by core and whole RNA polymerase. This protein factor appears to differ from the sigma factor and the M factor. The properties of this new factor and its mechanism of action have been explored.
D000249:Adenosine Monophosphate / Q000378:metabolism; D000596:Amino Acids; D001345:Autoradiography; D001426:Bacterial Proteins / Q000302:isolation & purification / Q000378:metabolism*; D002247:Carbon Isotopes; D002498:Centrifugation; D002845:Chromatography; D003470:Culture Media; D006152:Cyclic GMP / Q000378:metabolism; D004269:DNA, Bacterial / Q000378:metabolism; D004926:Escherichia coli / Q000032:analysis* / Q000378:metabolism; D008715:Methionine; D012316:RNA Nucleotidyltransferases / Q000378:metabolism; D012329:RNA, Bacterial / Q000096:biosynthesis*; D012270:Ribosomes / Q000032:analysis*; D013698:Templates, Genetic
D000596:Amino Acids; D001426:Bacterial Proteins; D002247:Carbon Isotopes; D003470:Culture Media; D004269:DNA, Bacterial; D012329:RNA, Bacterial; D000249:Adenosine Monophosphate; D008715:Methionine; D012316:RNA Nucleotidyltransferases; D006152:Cyclic GMP