title: 8-substituted theophyllines. In vitro inhibition of 3',5'-cyclic adenosine monophosphate phosphodiesterase and pharmacological spectrum in mice.
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology; D001786:Blood Glucose / Q000032:analysis; D001921:Brain / Q000201:enzymology; D002490:Central Nervous System / Q000187:drug effects; D000242:Cyclic AMP; D004295:Dihydroxyphenylalanine / Q000494:pharmacology; D004231:Diuresis / Q000187:drug effects; D004347:Drug Interactions; D004357:Drug Synergism; D006591:Hexobarbital / Q000494:pharmacology; D007274:Injections, Intraperitoneal; D007928:Lethal Dose 50; D051379:Mice; D008815:Mice, Inbred Strains; D009043:Motor Activity / Q000187:drug effects; D010433:Pentylenetetrazole / Q000494:pharmacology; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship; D013806:Theophylline / Q000008:administration & dosage / Q000494:pharmacology* / Q000633:toxicity; D013997:Time Factors
chemical_list: D000928:Antidepressive Agents; D001786:Blood Glucose; D004295:Dihydroxyphenylalanine; D006591:Hexobarbital; D013806:Theophylline; D000242:Cyclic AMP; D010744:Phosphoric Monoester Hydrolases; D010433:Pentylenetetrazole