title: Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes.
mesh_terms: D000633:Aminopyrine N-Demethylase / Q000096:biosynthesis; D000818:Animals; D001580:Benzopyrenes; D002248:Carbon Monoxide / Q000494:pharmacology; D003486:Cyanides / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D003574:Cytochrome c Group; D004790:Enzyme Induction; D005260:Female; D008099:Liver / Q000033:anatomy & histology / Q000187:drug effects; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects*; D006899:Mixed Function Oxygenases / Q000096:biosynthesis*; D009019:Morphinans; D009570:Nitriles / Q000494:pharmacology; D009929:Organ Size; D010088:Oxidoreductases / Q000096:biosynthesis; D010089:Oxidoreductases, N-Demethylating / Q000096:biosynthesis*; D010634:Phenobarbital / Q000494:pharmacology; D011284:Pregnenolone / Q000494:pharmacology*; D051381:Rats; D013053:Spectrophotometry
chemical_list: D001580:Benzopyrenes; D003486:Cyanides; D003574:Cytochrome c Group; D009019:Morphinans; D009570:Nitriles; D008748:Methylcholanthrene; D011284:Pregnenolone; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D010089:Oxidoreductases, N-Demethylating; D000633:Aminopyrine N-Demethylase; D010634:Phenobarbital