title: Cyclic adenosine monophosphate: function in photoreceptors.
abstract: Inactivation of adenylate cyclase in outer segments of retinal photoreceptor cells is proportional to the bleaching of rhodopsin. Membranes of the outer segments also contain a particulate, light-insensitive phosphodiesterase of high specific activity. In electrophysiological experiments, application of cyclic adenosine monophosphate along with a methylxanthine mimics the effects of illumination on the photoreceptor cell of the compound eye of Limulus.
mesh_terms: D000200:Action Potentials; D000262:Adenylyl Cyclases / Q000032:analysis / Q000502:physiology; D000818:Animals; D003386:Brachyura; D002417:Cattle; D000242:Cyclic AMP / Q000378:metabolism / Q000494:pharmacology*; D008029:Lighting; D008564:Membrane Potentials; D010786:Photoreceptor Cells / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D012160:Retina / Q000294:innervation; D014970:Xanthines / Q000494:pharmacology
chemical_list: D014970:Xanthines; D000242:Cyclic AMP; D000262:Adenylyl Cyclases