Activation of the carcinogen, N-hydroxy-2-fluorenylbenzene-sulfonamide, by desulfonylation to N-2-fluorenylhydroxylamine in vivo.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000139:chemically induced*; D002855:Chromatography, Thin Layer; D005260:Female; D005449:Fluorenes / Q000378:metabolism*; D006898:Hydroxylamines; D007274:Injections, Intraperitoneal; D008113:Liver Neoplasms / Q000139:chemically induced*; D008297:Male; D009374:Neoplasms, Experimental; D051381:Rats; D013449:Sulfonamides / Q000378:metabolism*
D005449:Fluorenes; D006898:Hydroxylamines; D013449:Sulfonamides