In vivo effects of intercalating drugs on the superhelix density of mitochondrial DNA isolated from human and mouse cells in culture.
D000166:Acridines / Q000494:pharmacology; D000818:Animals; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D002499:Centrifugation, Density Gradient; D004247:DNA / Q000302:isolation & purification / Q000378:metabolism*; D003609:Dactinomycin / Q000494:pharmacology; D006128:Growth / Q000187:drug effects; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D051379:Mice; D008854:Microscopy, Electron; D008856:Microscopy, Fluorescence; D008928:Mitochondria / Q000187:drug effects* / Q000378:metabolism; D010617:Phenanthridines / Q000494:pharmacology; D010710:Phosphates / Q000378:metabolism; D010759:Phosphorus Isotopes; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D011804:Quinolines / Q000494:pharmacology*; D013539:Simian virus 40; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014316:Tritium
D000166:Acridines; D010617:Phenanthridines; D010710:Phosphates; D010759:Phosphorus Isotopes; D000644:Quaternary Ammonium Compounds; D011804:Quinolines; D014316:Tritium; D003609:Dactinomycin; D004247:DNA; D013936:Thymidine