title: Collagen synthesis in human skin fibroblasts: effects of ascorbate,  -ketoglutarate and ferrous ion on proline hydroxylation.
mesh_terms: D001205:Ascorbic Acid / Q000494:pharmacology* / Q000633:toxicity; D002455:Cell Division; D003094:Collagen / Q000096:biosynthesis*; D003470:Culture Media; D046508:Culture Techniques; D004247:DNA / Q000378:metabolism; D004171:Diploidy; D005347:Fibroblasts / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D006801:Humans; D006900:Hydroxylation; D006909:Hydroxyproline / Q000096:biosynthesis; D007501:Iron / Q000494:pharmacology*; D007656:Ketoglutaric Acids / Q000494:pharmacology*; D008297:Male; D009994:Osmolar Concentration; D011393:Procollagen-Proline Dioxygenase / Q000378:metabolism; D011392:Proline / Q000378:metabolism*; D012867:Skin / Q000196:embryology / Q000378:metabolism; D012964:Sodium / Q000494:pharmacology
chemical_list: D003470:Culture Media; D007656:Ketoglutaric Acids; D003094:Collagen; D004247:DNA; D011392:Proline; D012964:Sodium; D007501:Iron; D011393:Procollagen-Proline Dioxygenase; D001205:Ascorbic Acid; D006909:Hydroxyproline