Increased concentrations of cyclic 3',5'-adenosine monophosphate without a physiological response after antidiuretic hormone.
Treatment of the serosal surface of the isolated bladders of toads (Bufo marinus) with phospholipase C inhibited the hydro-osmotic response to ADH, but did not prevent the rise in cyclic AMP concentrations associated with hormone action.
D000818:Animals; D002024:Bufo marinus; D000242:Cyclic AMP / Q000378:metabolism*; D066298:In Vitro Techniques; D009995:Osmosis; D010740:Phospholipases / Q000494:pharmacology*; D001743:Urinary Bladder / Q000187:drug effects* / Q000378:metabolism; D014667:Vasopressins / Q000037:antagonists & inhibitors*
D014667:Vasopressins; D000242:Cyclic AMP; D010740:Phospholipases