Affinity labeling of steroid binding sites. Synthesis of 16 -bromoacetoxyprogesterone and its use for affinity labeling of 20 -hydroxysteroid dehydrogenase.
D000085:Acetates; D000478:Alkylation; D000596:Amino Acids; D001665:Binding Sites; D001966:Bromine; D003348:Cortisone; D003460:Crystallization; D004355:Drug Stability; D004952:Esters / Q000138:chemical synthesis; D006639:Histidine; D006908:Hydroxyprogesterones / Q000138:chemical synthesis; D006913:Hydroxysteroid Dehydrogenases / Q000037:antagonists & inhibitors; D007553:Isotope Labeling; D008623:Mercaptoethanol; D008956:Models, Chemical; D008961:Models, Structural; D009243:NAD; D010084:Oxidation-Reduction; D011374:Progesterone; D013302:Streptomyces / Q000201:enzymology; D013329:Structure-Activity Relationship; D014316:Tritium
D000085:Acetates; D000596:Amino Acids; D004952:Esters; D006908:Hydroxyprogesterones; D009243:NAD; D014316:Tritium; D011374:Progesterone; D006639:Histidine; D008623:Mercaptoethanol; D006913:Hydroxysteroid Dehydrogenases; D001966:Bromine; D003348:Cortisone