title: Studies on the active site of clostripain. The specific inactivation by the chloromethyl ketone derived from  -N-tosyl-L-lysine.
mesh_terms: D000096:Acetone; D000478:Alkylation; D000578:Amidines; D001120:Arginine; D001565:Benzoates; D001665:Binding Sites; D001966:Bromine; D002713:Chlorine; D002845:Chromatography; D003013:Clostridium / Q000201:enzymology*; D004229:Dithiothreitol; D010450:Endopeptidases / Q000302:isolation & purification; D004789:Enzyme Activation; D006882:Hydroxyapatites; D007461:Iodoacetates; D007659:Ketones; D007700:Kinetics; D008239:Lysine; D003012:Microbial Collagenase; D010649:Phenylalanine; D011480:Protease Inhibitors; D011485:Protein Binding; D014105:Tosyl Compounds; D014316:Tritium
chemical_list: D000578:Amidines; D001565:Benzoates; D006882:Hydroxyapatites; D007461:Iodoacetates; D007659:Ketones; D011480:Protease Inhibitors; D014105:Tosyl Compounds; D014316:Tritium; D000096:Acetone; D010649:Phenylalanine; D002713:Chlorine; D001120:Arginine; D010450:Endopeptidases; D003012:Microbial Collagenase; D008239:Lysine; D001966:Bromine; D004229:Dithiothreitol