Inhibition of protein synthesis in L cells infected with vesicular stomatitis virus.
The inhibition of protein synthesis in L cells by vesicular stomatitis virus (VSV) requires the synthesis of new protein subsequent to virus infection. However, two mechanisms may be involved in the inhibition of cell protein synthesis by VSV: an initial, multiplicity-dependent, ultraviolet-insensitive inhibition and a progressive, ultraviolet-sensitive inhibition.
D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology; D005374:Filtration; D007739:L Cells / Q000187:drug effects / Q000378:metabolism*; D007930:Leucine / Q000378:metabolism; D051379:Mice; D014176:Protein Biosynthesis; D013997:Time Factors; D014238:Trichloroacetic Acid; D014316:Tritium; D014466:Ultraviolet Rays; D014721:Vesicular stomatitis Indiana virus / Q000528:radiation effects*
D014316:Tritium; D014238:Trichloroacetic Acid; D003513:Cycloheximide; D007930:Leucine