DNA-dependent DNA polymerases I and II from normal human-blood lymphocytes.
Two DNA polymerases have been purified from blood lymphocytes of normal human individuals. In contrast to a DNA polymerase isolated from lymphoblasts from individuals with leukemia, neither of the DNA polymerases from normal lymphocytes transcribes the heteropolymeric regions of tumor-virus RNA into DNA.
D000818:Animals; D001354:Avian Leukosis Virus / Q000032:analysis; D002499:Centrifugation, Density Gradient; D002848:Chromatography, DEAE-Cellulose; D002850:Chromatography, Gel; D004247:DNA / Q000097:blood*; D004254:DNA Nucleotidyltransferases / Q000097:blood* / Q000302:isolation & purification; D004273:DNA, Neoplasm / Q000097:blood; D004591:Electrophoresis, Polyacrylamide Gel; D005914:Globins / Q000032:analysis; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology*; D008297:Male; D008970:Molecular Weight; D009691:Nucleic Acid Denaturation; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000302:isolation & purification; D012334:RNA, Neoplasm / Q000097:blood; D012367:RNA, Viral / Q000302:isolation & purification; D011817:Rabbits; D012474:Salmon; D013094:Spermatozoa / Q000032:analysis; D013698:Templates, Genetic
D004273:DNA, Neoplasm; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D012367:RNA, Viral; D005914:Globins; D004247:DNA; D004254:DNA Nucleotidyltransferases