Differences between the ribonucleic acids of transforming and nontransforming avian tumor viruses.
The 60-70S RNAs of several transforming and nontransforming avian tumor viruses have different electrophoretic mobilities. The RNA of transforming viruses contains two electrophoretically separable subunit classes: a and b. The relative concentrations of these subunits vary with the virus strain. Avian leukosis viruses and nontransforming derivatives of a sarcoma virus lack subunits of class a. It is suggested that the presence of the class a subunit is related to the transforming ability for fibroblasts of the virus.
D001355:Alpharetrovirus / Q000302:isolation & purification; D000818:Animals; D002471:Cell Transformation, Neoplastic; D002645:Chickens; D004586:Electrophoresis; D005347:Fibroblasts / Q000382:microbiology; D005354:Fibrosarcoma / Q000382:microbiology; D012367:RNA, Viral / Q000032:analysis*; D014316:Tritium; D014529:Uridine / Q000378:metabolism
D012367:RNA, Viral; D014316:Tritium; D014529:Uridine