Antigenic study of unfertilized mouse eggs: cross reactivity with SV40-induced antigens.
Serum obtained from guinea pigs immunized with unfertilized C57BL/6 mouse eggs was found to be cytotoxic in the presence of complement for eggs obtained from syngeneic and allogeneic mice. The anti-egg serum was not cytotoxic for rat eggs, lymph node cells, methylcholanthrene-induced tumor cells, or 3T3 cells obtained either from syngeneic or allogeneic mice. The anti-egg serum was, however, cytotoxic for SV40-transformed 3T3 cells and C57BL/6 cells. After absorption with SV40-transformed cells, anti-egg serum lost its cytotoxicity for mouse eggs.
D000818:Animals; D000941:Antigens; D000970:Antineoplastic Agents; D002460:Cell Line; D003165:Complement System Proteins; D003429:Cross Reactions; D005260:Female; D005455:Fluorescent Antibody Technique; D006168:Guinea Pigs; D008198:Lymph Nodes / Q000166:cytology; D008748:Methylcholanthrene; D051379:Mice; D010063:Ovum / Q000276:immunology*; D051381:Rats; D013539:Simian virus 40
D000941:Antigens; D000970:Antineoplastic Agents; D008748:Methylcholanthrene; D003165:Complement System Proteins