Superinfection of simian virus 40-transformed permissive cells with simian virus 40.
Evidence that the resistance of simian virus (SV40)-transformed permissive cells to superinfection with SV40 is due to lack of virus uptake is presented. When virus uptake is enhanced, the events of infection proceed as in normal permissive cells, resulting in production of infectious virus.
D000327:Adsorption; D000818:Animals; D001345:Autoradiography; D002460:Cell Line; D002467:Cell Nucleus / Q000382:microbiology; D002471:Cell Transformation, Neoplastic; D002499:Centrifugation, Density Gradient; D002586:Cesium; D002712:Chlorides; D003470:Culture Media; D046508:Culture Techniques; D003593:Cytoplasm / Q000382:microbiology; D005347:Fibroblasts; D005455:Fluorescent Antibody Technique; D000882:Haplorhini; D007668:Kidney; D007930:Leucine; D051379:Mice; D011120:Polyomavirus / Q000472:pathogenicity; D013539:Simian virus 40 / Q000254:growth & development / Q000302:isolation & purification / Q000472:pathogenicity*; D013936:Thymidine; D014316:Tritium; D014779:Virus Replication
D002712:Chlorides; D003470:Culture Media; D014316:Tritium; D002586:Cesium; D007930:Leucine; D013936:Thymidine