Analysis of chemotaxis in white blood cells.
We wish to report the development of an assay system for the study of white blood cells in vitro. With this system we have demonstrated that a yet unidentified substance found in red blood cell membranes and cyclic adenosine monophosphate (cAMP) cause the chemotactic response in white blood cells. We have not yet determined whether the substance released from the membrane is cAMP.
D000818:Animals; D002462:Cell Membrane / Q000032:analysis; D002633:Chemotaxis; D000242:Cyclic AMP / Q000494:pharmacology; D004912:Erythrocytes / Q000032:analysis; D006736:Horses; D066298:In Vitro Techniques; D007962:Leukocytes / Q000187:drug effects / Q000502:physiology*
D000242:Cyclic AMP