title: Vasoactive hormones in endotoxin shock: a comparative study in cats and dogs.
abstract: 1. Entamoeba coli endotoxin was administered intravenously to cats and dogs.2. The changes in circulating levels of catecholamines and angiotensin following endotoxin were assayed by a continuous superfusion technique.3. The response of the dog was characterized by an immediate sustained rise in angiotensin levels and a later variable rise in catecholamine levels.4. The response of the cat was characterized by an early rise in catecholamine levels and a later rise in angiotensin levels.5. It is concluded that this species difference may reflect the relative importance of renin-angiotensin and sympatho-adrenal systems of dogs and cats, respectively.
mesh_terms: D000311:Adrenal Glands / Q000502:physiology; D000804:Angiotensin II / Q000097:blood* / Q000494:pharmacology; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002395:Catecholamines / Q000097:blood*; D002415:Cats; D002496:Central Venous Pressure / Q000187:drug effects; D003106:Colon / Q000187:drug effects; D004285:Dogs; D004558:Electric Stimulation; D004731:Endotoxins; D004747:Entamoeba; D004837:Epinephrine / Q000097:blood / Q000494:pharmacology; D005260:Female; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D011433:Propranolol / Q000494:pharmacology; D012083:Renin; D012772:Shock, Septic / Q000097:blood*; D013045:Species Specificity; D013270:Stomach / Q000187:drug effects; D013564:Sympathetic Nervous System / Q000502:physiology
chemical_list: D002395:Catecholamines; D004731:Endotoxins; D000804:Angiotensin II; D011433:Propranolol; D012083:Renin; D004837:Epinephrine