Role of noradrenaline in the acute pressor response to angiotensin in conscious cats.
The changes in the pressor responses to angiotensin after treatment with substances known to modify sympathetic function have been compared with the changes in the responses to noradrenaline, tyramine and McN-A-343 using conscious cats. The responses to angiotensin were not reduced by blockade of adrenergic neurones, alpha and beta-adrenoceptors, or of autonomic ganglia. In conscious cats the acute pressor response to angiotensin does not appear to be related directly to stimulation or facilitation of transmission in sympathetic ganglia or to release of catecholamines from tissue stores.
D000804:Angiotensin II / Q000494:pharmacology*; D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects*; D002219:Carbamates / Q000494:pharmacology; D002415:Cats; D006146:Guanidines / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology*; D010646:Phentolamine / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology; D014439:Tyramine / Q000494:pharmacology
D000959:Antihypertensive Agents; D002219:Carbamates; D006146:Guanidines; D000644:Quaternary Ammonium Compounds; D000804:Angiotensin II; D011433:Propranolol; D009638:Norepinephrine; D014439:Tyramine; D010646:Phentolamine