Lowered ovarian conversion of 14C-pregnenolone to progesterone and other metabolites during phenobarbital (PB) block of PMS-induced ovulation in immature rats: inhibition of 3beta-hydroxysteroid dehydrogenation.
D006907:17-alpha-Hydroxypregnenolone / Q000378:metabolism; D000367:Age Factors; D000818:Animals; D002247:Carbon Isotopes; D004966:Estrogens, Conjugated (USP) / Q000494:pharmacology; D004971:Estrus; D005260:Female; D006865:Hydrogenation; D006908:Hydroxyprogesterones / Q000378:metabolism; D006914:Hydroxysteroids / Q000378:metabolism; D007659:Ketones / Q000378:metabolism; D010053:Ovary / Q000187:drug effects / Q000378:metabolism*; D010060:Ovulation / Q000187:drug effects; D010634:Phenobarbital / Q000494:pharmacology*; D011247:Pregnancy; D011278:Pregnanes / Q000378:metabolism; D011284:Pregnenolone / Q000378:metabolism*; D011374:Progesterone / Q000378:metabolism*; D051381:Rats
D002247:Carbon Isotopes; D004966:Estrogens, Conjugated (USP); D006908:Hydroxyprogesterones; D006914:Hydroxysteroids; D007659:Ketones; D011278:Pregnanes; D006907:17-alpha-Hydroxypregnenolone; D011374:Progesterone; D011284:Pregnenolone; D010634:Phenobarbital