Accelerated erythrocyte 5-phosphoribosyl-1-pyrophosphate synthesis. A familial abnormality associated with excessive uric acid production and gout.
D000328:Adult; D000493:Allopurinol / Q000627:therapeutic use; D011756:Diphosphates / Q000096:biosynthesis / Q000097:blood*; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism*; D006073:Gout / Q000097:blood / Q000188:drug therapy / Q000201:enzymology / Q000235:genetics* / Q000378:metabolism; D006147:Guanine; D006801:Humans; D007042:Hypoxanthines; D008297:Male; D009711:Nucleotides / Q000378:metabolism; D010428:Pentosephosphates / Q000096:biosynthesis / Q000097:blood*; D010430:Pentosyltransferases / Q000097:blood; D011687:Purines / Q000378:metabolism; D012266:Ribose / Q000097:blood; D014527:Uric Acid / Q000096:biosynthesis
D011756:Diphosphates; D007042:Hypoxanthines; D009711:Nucleotides; D010428:Pentosephosphates; D011687:Purines; D014527:Uric Acid; D006147:Guanine; D000493:Allopurinol; D012266:Ribose; D010430:Pentosyltransferases