title: Protein phospholinase reactions in mammalian testis. Stimulatory effects of adenosine 3':5'-cyclic monophosphate on the phosphorylation of basic proteins.
abstract: The soluble fraction of rat testis homogenates is rich in enzymes catalysing the phosphorylation by ATP of many different proteins. The phosphorylation of certain histones, and also of a homogeneous basic protein from guinea-pig seminal-vesicle secretion, is markedly enhanced by 3':5'-cyclic AMP. Various factors affecting these reactions as catalysed by partially purified testicular enzyme preparations are described, and their possible physiological significance is discussed.
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D002369:Castration; D002499:Centrifugation, Density Gradient; D002848:Chromatography, DEAE-Cellulose; D000242:Cyclic AMP / Q000494:pharmacology*; D005260:Female; D006657:Histones / Q000378:metabolism; D008297:Male; D009994:Osmolar Concentration; D010750:Phosphoproteins / Q000096:biosynthesis; D010759:Phosphorus Isotopes; D010770:Phosphotransferases / Q000302:isolation & purification / Q000378:metabolism*; D011467:Prostate / Q000201:enzymology; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D012669:Seminal Vesicles / Q000378:metabolism; D013696:Temperature; D013737:Testis / Q000201:enzymology*; D013739:Testosterone / Q000494:pharmacology; D014461:Ultracentrifugation; D014599:Uterus / Q000201:enzymology
chemical_list: D006657:Histones; D010750:Phosphoproteins; D010759:Phosphorus Isotopes; D011506:Proteins; D013739:Testosterone; D000255:Adenosine Triphosphate; D000242:Cyclic AMP; D010770:Phosphotransferases