title: Equine abortion (herpes) virus: strain differences in susceptibility to inactivation by dithiothreitol.
abstract: The infectivity of equine abortion (herpes) virus (EAV) was inactivated by treatment with reduced dithiothreitol (DTT). According to their susceptibility to DTT, the EAV strains could be divided into three groups. The vaccine strain RAC-H (419) proved to be more resistant to DTT than all of the other 14 strains tested. The hemagglutinin of EAV was also inactivated by DTT; no strain differences were observed in this respect.
mesh_terms: D000034:Abortion, Veterinary; D000818:Animals; D002417:Cattle; D002460:Cell Line / Q000382:microbiology; D002999:Clone Cells; D004229:Dithiothreitol / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D005260:Female; D006386:Hemagglutination Tests; D006389:Hemagglutinins, Viral / Q000037:antagonists & inhibitors; D006564:Herpesviridae / Q000187:drug effects* / Q000254:growth & development / Q000276:immunology; D006566:Herpesviridae Infections / Q000662:veterinary; D006734:Horse Diseases; D006736:Horses; D007668:Kidney; D007739:L Cells / Q000382:microbiology; D008168:Lung; D051379:Mice; D009976:Orthomyxoviridae Infections / Q000662:veterinary; D011247:Pregnancy; D013552:Swine; D014765:Viral Vaccines; D014776:Virus Cultivation
chemical_list: D006389:Hemagglutinins, Viral; D014765:Viral Vaccines; D004229:Dithiothreitol