Mouse leukemia: depression of serum interferon production.
Production of circulating interferon is significantly impaired in AKR/J mice after development of lymphoblastic leukemia and in Balb/c mice with clinical signs of Friend erythroblastic leukemia. This alteration has been observed with three interferon inducers, each one known to elicit an interferon response in different cells.
D000367:Age Factors; D000818:Animals; D004686:Encephalomyocarditis virus; D005260:Female; D005622:Friend murine leukemia virus; D007372:Interferons / Q000096:biosynthesis / Q000097:blood*; D007942:Leukemia, Experimental / Q000097:blood* / Q000382:microbiology; D007945:Leukemia, Lymphoid / Q000097:blood*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009522:Newcastle disease virus; D011119:Polynucleotides / Q000494:pharmacology
D011119:Polynucleotides; D007372:Interferons