Neuropathy associated with hepatitis in patients maintained on haemodialysis.
During a study of peripheral nerve function in chronic renal failure, 11 patients who were being treated by chronic intermittent haemodialysis developed serum hepatitis. Before the infection there was a trend towards improvement in nerve conduction velocities. A pronounced deterioration in the conduction velocities in motor fibres of peripheral nerves occurred in association with hepatitis. In the months after recovery from the infection there was again a trend towards improvement in conduction velocities. We suggest that this reflects the occurrence of a peripheral neuropathy which is at least in part demyelinating. The neuropathy is related to the serum hepatitis, but its pathogenesis is indeterminate.
D002908:Chronic Disease; D003289:Convalescence; D003711:Demyelinating Diseases / Q000209:etiology / Q000503:physiopathology; D006509:Hepatitis B / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008475:Median Nerve / Q000503:physiopathology; D009046:Motor Neurons; D009431:Neural Conduction; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D006435:Renal Dialysis / Q000009:adverse effects*