Medium-scale production and purification of ochratoxin A, a metabolite of Aspergillus ochraceus.
The preparation of crystalline ochratoxin A from Aspergillus ochraceus nutrient solution is described. Methods are adaptable to large-scale fermentations.
D001230:Aspergillus / Q000254:growth & development / Q000378:metabolism*; D001554:Benzene; D001639:Bicarbonates; D002725:Chloroform; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D003374:Coumarins / Q000302:isolation & purification*; D003460:Crystallization; D003470:Culture Media; D005285:Fermentation; D005374:Filtration; D005561:Formates; D005782:Gels; D013058:Mass Spectrometry; D008722:Methods; D009183:Mycotoxins / Q000302:isolation & purification*; D009793:Ochratoxins / Q000096:biosynthesis / Q000302:isolation & purification; D012822:Silicon Dioxide; D012997:Solvents
D001639:Bicarbonates; D003374:Coumarins; D003470:Culture Media; D005561:Formates; D005782:Gels; D009183:Mycotoxins; D009793:Ochratoxins; D012997:Solvents; D012822:Silicon Dioxide; D002725:Chloroform; D001554:Benzene