title: Primary hepatoma and hepatitis-associated antigen in a young white woman.
abstract: A young woman whose serum was positive for hepatitis-associated antigen (H.A.A.) and alpha-fetoprotein developed a malignant hepatoma. Though the light-microscopical appearances of the surrounding liver tissue were normal, electronmicroscope examination of the tumour tissue disclosed both C-virus-like particles and H.A.A. particles. Possibly there was a causal connexion between one of these particles and the hepatoma.
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000382:microbiology* / Q000473:pathology; D005260:Female; D005326:Fetal Proteins / Q000032:analysis; D006511:Hepatitis B Antigens / Q000302:isolation & purification*; D006801:Humans; D007181:Inclusion Bodies, Viral; D008113:Liver Neoplasms / Q000097:blood / Q000382:microbiology* / Q000473:pathology; D008854:Microscopy, Electron; D012190:Retroviridae / Q000302:isolation & purification
chemical_list: D005326:Fetal Proteins; D006511:Hepatitis B Antigens