Incidence of ocular complications in patients undergoing renal transplantation.
The eyes of 39 patients who had received allogenic renal transplants were examined for signs of disease. Nine (23%) had early posterior subcapsular cataracts, two (5%) developed acute cytomegalovirus retinitis, and one developed steroid-induced glaucoma. The lesions which were found were all attributable to the immunosuppressive drug therapy. Thirty-five (87%) had detectable complement-fixing antibodies to cytomegalovirus.
D000293:Adolescent; D000328:Adult; D000906:Antibodies; D002386:Cataract / Q000209:etiology; D003168:Complement Fixation Tests; D003520:Cyclophosphamide / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification; D005128:Eye Diseases / Q000209:etiology*; D005260:Female; D005901:Glaucoma / Q000139:chemically induced; D006566:Herpesviridae Infections; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D011183:Postoperative Complications; D012166:Retinal Hemorrhage / Q000209:etiology; D012173:Retinitis / Q000209:etiology / Q000382:microbiology; D014184:Transplantation, Homologous
D000906:Antibodies; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide