The role of the sympathetic nervous system in hypoglycaemia-stimulated gastric secretion.
The gastric secretory response to insulin is mediated predominantly by the vagus. The associated hypoglycaemia stress response is mediated by the sympathetic nervous system. Inhibition of the sympathetic response by simultaneous alpha and beta receptor blockade was studied in five healthy young adults. No appreciable modification of gastric secretory output resulted.
D000324:Adrenocorticotropic Hormone / Q000502:physiology; D000328:Adult; D001786:Blood Glucose; D003346:Corticotropin-Releasing Hormone / Q000502:physiology; D005750:Gastric Juice / Q000378:metabolism*; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced; D007328:Insulin / Q000494:pharmacology; D011433:Propranolol / Q000494:pharmacology; D012636:Secretory Rate / Q000187:drug effects; D013564:Sympathetic Nervous System / Q000502:physiology*; D013997:Time Factors; D014630:Vagus Nerve / Q000502:physiology
D001786:Blood Glucose; D007328:Insulin; D000324:Adrenocorticotropic Hormone; D003346:Corticotropin-Releasing Hormone; D011433:Propranolol