Inhibition of steroid 3-sulfatase by endogenous steroids. A possible mechanism controlling placental estrogen synthesis from conjugated precursors.
D015065:17-Hydroxycorticosteroids / Q000097:blood; D015068:17-Ketosteroids / Q000378:metabolism*; D000731:Androstanes / Q000097:blood / Q000378:metabolism*; D002247:Carbon Isotopes; D002854:Chromatography, Paper; D002855:Chromatography, Thin Layer; D003687:Dehydroepiandrosterone / Q000097:blood / Q000378:metabolism*; D004721:Endoplasmic Reticulum / Q000201:enzymology; D004964:Estriol / Q000097:blood; D004967:Estrogens / Q000096:biosynthesis*; D005246:Feedback; D005260:Female; D006801:Humans; D006913:Hydroxysteroid Dehydrogenases / Q000032:analysis; D066298:In Vitro Techniques; D007535:Isomerases / Q000032:analysis; D009243:NAD / Q000378:metabolism; D010920:Placenta / Q000201:enzymology / Q000378:metabolism*; D011247:Pregnancy; D011284:Pregnenolone / Q000097:blood / Q000378:metabolism; D011374:Progesterone / Q000096:biosynthesis / Q000097:blood; D013261:Sterols / Q000097:blood; D013429:Sulfatases / Q000037:antagonists & inhibitors*; D013431:Sulfates / Q000097:blood; D014316:Tritium
D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids; D000731:Androstanes; D002247:Carbon Isotopes; D004967:Estrogens; D013261:Sterols; D013431:Sulfates; D009243:NAD; D014316:Tritium; D003687:Dehydroepiandrosterone; D011374:Progesterone; D011284:Pregnenolone; D006913:Hydroxysteroid Dehydrogenases; D013429:Sulfatases; D007535:Isomerases; D004964:Estriol