Angiotensin-forming enzyme in brain tissue.
A renin-like enzyme is present in brain tissue and is independent of kidney and plasma renin. In the presence of homologous substrate it forms angiotensin. Administration of aldosterone significantly decreases this angiotensinforming enzyme activity, while administration of progesterone markedly enhances it.
D000450:Aldosterone / Q000494:pharmacology; D000804:Angiotensin II / Q000096:biosynthesis*; D000818:Animals; D001923:Brain Chemistry; D002421:Caudate Nucleus / Q000032:analysis / Q000187:drug effects / Q000201:enzymology*; D003864:Depression, Chemical; D004285:Dogs; D011374:Progesterone / Q000494:pharmacology; D012083:Renin / Q000032:analysis*; D012964:Sodium / Q000378:metabolism; D013268:Stimulation, Chemical
D000804:Angiotensin II; D000450:Aldosterone; D011374:Progesterone; D012964:Sodium; D012083:Renin