Synthesis of 5-fluorouridine 5'-phosphate by a pyrimidine phosphoribosyltransferase of mammalian origin. II. Correlation between the tumor levels of the enzyme and the 5-fluorouracil-promoted increase in survival of tumor-bearing mice.
D000818:Animals; D005472:Fluorouracil / Q000378:metabolism* / Q000627:therapeutic use*; D007939:Leukemia L1210 / Q000188:drug therapy / Q000201:enzymology; D008223:Lymphoma / Q000188:drug therapy / Q000201:enzymology; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000188:drug therapy* / Q000201:enzymology*; D010428:Pentosephosphates; D010756:Phosphoric Acids; D012266:Ribose; D014166:Transferases; D014500:Uracil Nucleotides / Q000096:biosynthesis*
D010428:Pentosephosphates; D010756:Phosphoric Acids; D014500:Uracil Nucleotides; D012266:Ribose; D014166:Transferases; D005472:Fluorouracil