Enhancement by poly-D-lysine of poly I: C-induced interferon production in mice.
Poly-d-lysine of high molecular weight enhances interferon induction in mice by the double-stranded complex of polyinosinic and polycytidylic acids and is superior to diethylaminoethyl-dextran in this respect.
D000818:Animals; D046508:Culture Techniques; D003588:Cytopathogenic Effect, Viral; D003597:Cytosine Nucleotides / Q000494:pharmacology*; D003911:Dextrans / Q000494:pharmacology; D004357:Drug Synergism; D005021:Ethylamines / Q000494:pharmacology; D005260:Female; D007274:Injections, Intraperitoneal; D007372:Interferons / Q000096:biosynthesis*; D007739:L Cells; D008239:Lysine / Q000494:pharmacology*; D051379:Mice; D008970:Molecular Weight; D009705:Nucleosides / Q000494:pharmacology*; D013237:Stereoisomerism; D013268:Stimulation, Chemical; D014721:Vesicular stomatitis Indiana virus
D003597:Cytosine Nucleotides; D003911:Dextrans; D005021:Ethylamines; D009705:Nucleosides; D007372:Interferons; D008239:Lysine