Adenosine 3',5'-monophosphate in nervous tissue: increase associated with synaptic transmission.
Brief periods of stimulation of the preganglionic nerve fibers produced a severalfold increase in the content of adenosine 3',5'-monophosphate in superior cervical sympathetic ganglia, whereas postganglionic stimulation did not. These and other experiments indicated that the increased concentrations of adenosine 3'5'-monophosphate were closely associated with the process of synaptic transmission. This increase occurred primarily in postsynaptic cells.
D000227:Adenine Nucleotides / Q000378:metabolism*; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001338:Autonomic Fibers, Postganglionic / Q000378:metabolism*; D001339:Autonomic Fibers, Preganglionic / Q000502:physiology*; D000242:Cyclic AMP / Q000378:metabolism
D000227:Adenine Nucleotides; D001285:Atropine; D000242:Cyclic AMP