Vasopressin: effect on deformability of urinary surface of collecting duct cells.
In isolated renal collecting ducts vasopressin decreased the negative pressure required to suck a hemispherical bulge of the epitheliat cells' urinary surface into the tip of a micropipette. Increased surface deformability may be related to the increased permeability to water which also occurs in the apex of the cells in response to the hormone.
D000818:Animals; D000242:Cyclic AMP / Q000494:pharmacology; D004848:Epithelium / Q000187:drug effects; D005260:Female; D007684:Kidney Tubules / Q000187:drug effects*; D010539:Permeability; D011312:Pressure; D011817:Rabbits; D013499:Surface Properties; D013500:Surface Tension; D013806:Theophylline / Q000494:pharmacology; D014667:Vasopressins / Q000494:pharmacology*
D014667:Vasopressins; D013806:Theophylline; D000242:Cyclic AMP