title: Proteins of polyhedal cytoplasmic deoxyvirus. II. Nucleotide phosphohydrolase activity associated with frog virus 3.
abstract: A nucleotide phosphohydrolase is firmly associated with a purified polyhedral cytoplasmic deoxyvirus, frog virus 3. This adenosine triphosphatase is distinguishable from known mammalian cell adenosine triphosphatases and from adenosine triphosphatase of an unrelated cytoplasmic replicating virus grown in the same host cell. The enzyme activity has a high specificity for adenosine triphosphate; the product of the reaction is adenosine diphosphate. The presence of similar activities in reovirus and poxvirus indicates that adenosine triphosphatase might have a function in the replication of these viruses.
mesh_terms: D000244:Adenosine Diphosphate / Q000096:biosynthesis; D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001001:Anura; D001386:Azides / Q000494:pharmacology; D002460:Cell Line; D002499:Centrifugation, Density Gradient; D002854:Chromatography, Paper; D006224:Cricetinae; D004267:DNA Viruses / Q000201:enzymology* / Q000302:isolation & purification / Q000378:metabolism; D003902:Detergents / Q000494:pharmacology; D011756:Diphosphates / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007668:Kidney; D008623:Mercaptoethanol / Q000494:pharmacology; D010042:Ouabain / Q000494:pharmacology; D010710:Phosphates / Q000494:pharmacology; D010759:Phosphorus Isotopes; D011212:Poxviridae / Q000201:enzymology; D011817:Rabbits; D013045:Species Specificity; D013395:Sucrose; D013696:Temperature; D014316:Tritium; D014776:Virus Cultivation
chemical_list: D000900:Anti-Bacterial Agents; D001386:Azides; D003902:Detergents; D011756:Diphosphates; D010710:Phosphates; D010759:Phosphorus Isotopes; D014316:Tritium; D013395:Sucrose; D010042:Ouabain; D008623:Mercaptoethanol; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases