title: Inhibition of cyclic 3',5'-AMP phosphodiesterase in islet cells and other tissues by tolbutamide.
mesh_terms: D007516:Adenoma, Islet Cell / Q000201:enzymology* / Q000378:metabolism; D000645:Ammonium Sulfate; D000818:Animals; D001921:Brain / Q000201:enzymology; D006224:Cricetinae; D000242:Cyclic AMP / Q000037:antagonists & inhibitors*; D006868:Hydrolysis; D066298:In Vitro Techniques; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008168:Lung / Q000201:enzymology; D010744:Phosphoric Monoester Hydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D013453:Sulfonylurea Compounds / Q000494:pharmacology; D014044:Tolbutamide / Q000494:pharmacology*; D014316:Tritium; D014966:Xanthenes / Q000494:pharmacology
chemical_list: D007328:Insulin; D013453:Sulfonylurea Compounds; D014966:Xanthenes; D014316:Tritium; D014044:Tolbutamide; D000242:Cyclic AMP; D010744:Phosphoric Monoester Hydrolases; D000645:Ammonium Sulfate