Genome homology of vesicular stomatitis virus and defective T particles and evidence for the sequential transcription of the virion ribonucleic acid.
The small defective T particle of vesicular stomatitis virus (VSV-111) has no detectable enzyme activity when assayed at 31 C, although qualitatively it possesses all the virion proteins found in complete VSV-1 virions. With VSV-1 transcription product ribonucleic acid (RNA), it is shown that the VSV-111 RNA is identical to part of the VSV-1 genome. Evidence is also presented to support the idea that in vitro VSV-1 transcription is sequential.
D000818:Animals; D002460:Cell Line; D002499:Centrifugation, Density Gradient; D006224:Cricetinae; D003673:Defective Viruses / Q000032:analysis / Q000201:enzymology / Q000378:metabolism; D004589:Electrophoresis, Disc; D005815:Genetic Code; D005827:Genetics, Microbial; D007668:Kidney; D010759:Phosphorus Isotopes; D012316:RNA Nucleotidyltransferases / Q000378:metabolism; D012367:RNA, Viral / Q000032:analysis / Q000096:biosynthesis*; D012260:Ribonucleases; D014316:Tritium; D014500:Uracil Nucleotides / Q000378:metabolism; D014529:Uridine / Q000378:metabolism; D014721:Vesicular stomatitis Indiana virus / Q000032:analysis / Q000201:enzymology / Q000302:isolation & purification / Q000378:metabolism*; D014762:Viral Interference; D014776:Virus Cultivation
D010759:Phosphorus Isotopes; D012367:RNA, Viral; D014500:Uracil Nucleotides; D014316:Tritium; D012316:RNA Nucleotidyltransferases; D012260:Ribonucleases; D014529:Uridine