Substituted carbamides: interrelationship between anticonvulsant activity and inhibition of nicotinamide adenine dinucleotide-dependent pyruvic acid oxidation.
D000085:Acetates / Q000494:pharmacology; D000577:Amides / Q000494:pharmacology*; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D001921:Brain / Q000201:enzymology / Q000378:metabolism; D002219:Carbamates / Q000494:pharmacology*; D002713:Chlorine / Q000494:pharmacology; D004794:Enzyme Repression; D051379:Mice; D009020:Morphine; D009243:NAD / Q000037:antagonists & inhibitors*; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects*; D010880:Piperidines; D011760:Pyrrolidinones; D011771:Pyruvate Oxidase / Q000037:antagonists & inhibitors; D011773:Pyruvates / Q000378:metabolism*; D051381:Rats; D013329:Structure-Activity Relationship
D000085:Acetates; D000577:Amides; D000927:Anticonvulsants; D002219:Carbamates; D010880:Piperidines; D011760:Pyrrolidinones; D011773:Pyruvates; D009243:NAD; D002713:Chlorine; D009020:Morphine; D011771:Pyruvate Oxidase