Enzymatic activation of the carcinogen 4-hydroxyaminoquinoline-1-oxide and its interaction with cellular macromolecules.
D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D002247:Carbon Isotopes; D002273:Carcinogens / Q000378:metabolism*; D006528:Carcinoma, Hepatocellular / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D002854:Chromatography, Paper; D003497:Cyclic N-Oxides / Q000378:metabolism*; D003593:Cytoplasm / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D004273:DNA, Neoplasm / Q000378:metabolism; D004229:Dithiothreitol / Q000494:pharmacology; D008113:Liver Neoplasms; D008274:Magnesium / Q000494:pharmacology; D011804:Quinolines / Q000378:metabolism*; D012334:RNA, Neoplasm / Q000378:metabolism*; D051381:Rats; D012710:Serum Albumin, Bovine / Q000378:metabolism; D013347:Subcellular Fractions / Q000378:metabolism; D014316:Tritium
D002247:Carbon Isotopes; D002273:Carcinogens; D003497:Cyclic N-Oxides; D004273:DNA, Neoplasm; D011804:Quinolines; D012334:RNA, Neoplasm; D014316:Tritium; D012710:Serum Albumin, Bovine; D000255:Adenosine Triphosphate; D008274:Magnesium; D004229:Dithiothreitol