Urinary adenosine 3',5'-monophosphate in the switch process from depression to mania.
Marked elevations of urinary adenosine 3',5'-monophosphate occurred on the day of rapid switch from a depressed into a manic state in patients with manic-depressive illness. It is suggested that this increase might serve a trigger function for the process by which catecholamines are elevated during the manic phase of the illness.
D000227:Adenine Nucleotides / Q000652:urine*; D000328:Adult; D001714:Bipolar Disorder / Q000652:urine*; D000242:Cyclic AMP / Q000652:urine; D003863:Depression / Q000652:urine*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000652:urine; D011596:Psychomotor Disorders / Q000652:urine*; D012895:Sleep, REM
D000227:Adenine Nucleotides; D000242:Cyclic AMP; D009638:Norepinephrine