Cyclic 3',5'-nucleotide phosphodiesterase: cytochemical localization in cerebral cortex.
The distribution of cyclic 3',5'-nucleotide phosphodiesterase activity in rat cerebral cortex was determined by cytochemical methods. The detectable phosphodiesterase activity was localized in postsynaptic (dendritic) nerve endings, most of it immediately adjacent to the synaptic membrane. Most of the postsynaptic nerve endings showed phosphodiesterase activity.
D000249:Adenosine Monophosphate / Q000378:metabolism; D000818:Animals; D002540:Cerebral Cortex / Q000201:enzymology* / Q000378:metabolism; D000242:Cyclic AMP; D006651:Histocytochemistry; D008297:Male; D008854:Microscopy, Electron; D010744:Phosphoric Monoester Hydrolases / Q000032:analysis* / Q000378:metabolism; D051381:Rats; D013570:Synaptic Membranes / Q000201:enzymology
D000249:Adenosine Monophosphate; D000242:Cyclic AMP; D010744:Phosphoric Monoester Hydrolases