title: Characterization of an endonuclease associated with simian virus 40 virions.
abstract: An endonucleolytic activity associated with purified simian virus 40 (SV40) virions has been found. The enzyme is present in virions prepared from a number of different host lines. The enzyme is present in all early and late temperature-sensitive mutants examined. Some aspects of the endonucleolytic activity have been examined with SV40 deoxyribonucleic acid as substrate.
mesh_terms: D000818:Animals; D002247:Carbon Isotopes; D002460:Cell Line / Q000382:microbiology; D002499:Centrifugation, Density Gradient; D002501:Centrifugation, Zonal; D003168:Complement Fixation Tests; D004279:DNA, Viral / Q000302:isolation & purification / Q000378:metabolism; D004720:Endonucleases / Q000302:isolation & purification* / Q000378:metabolism; D004996:Ethidium; D005827:Genetics, Microbial; D000882:Haplorhini; D007668:Kidney; D009154:Mutation; D009500:Neutralization Tests; D013539:Simian virus 40 / Q000201:enzymology* / Q000254:growth & development / Q000302:isolation & purification; D013696:Temperature; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
chemical_list: D002247:Carbon Isotopes; D004279:DNA, Viral; D014316:Tritium; D004720:Endonucleases; D004996:Ethidium; D013936:Thymidine