Effect of colchicine, colcemid, and vinblastine on the agglutination, by concanavalin A, of transformed cells.
The sensitivity of transformed 3T3 fibroblasts to agglutination by concanavalin A is reduced by alkaloids that bind specifically to protein subunits of microtubules.
D000371:Agglutination / Q000187:drug effects*; D000818:Animals; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D003078:Colchicine / Q000494:pharmacology*; D003208:Concanavalin A / Q000037:antagonists & inhibitors; D004912:Erythrocytes / Q000276:immunology; D006382:Hemadsorption; D006384:Hemagglutination; D037102:Lectins / Q000037:antagonists & inhibitors*; D051379:Mice; D013539:Simian virus 40; D014747:Vinblastine / Q000494:pharmacology*
D037102:Lectins; D003208:Concanavalin A; D014747:Vinblastine; D003078:Colchicine