Inhibition of aldehyde dehydrogenase by 2-chloroacetophenone and the resultant effects on the catabolism of norepinephrine in brain.
D000447:Aldehydes; D000818:Animals; D001921:Brain / Q000166:cytology / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects*; D002247:Carbon Isotopes; D055598:Chemical Phenomena; D002621:Chemistry; D004336:Drug Antagonism; D004987:Ethers / Q000096:biosynthesis; D005453:Fluorescence; D005978:Glutathione / Q000494:pharmacology; D006018:Glycols / Q000096:biosynthesis; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008333:Mandelic Acids / Q000096:biosynthesis; D008433:Mathematics; D008928:Mitochondria / Q000187:drug effects / Q000201:enzymology; D009243:NAD; D009638:Norepinephrine / Q000378:metabolism*; D010088:Oxidoreductases / Q000037:antagonists & inhibitors*; D010636:Phenols / Q000096:biosynthesis; D011422:Propionates; D011817:Rabbits; D013439:Sulfhydryl Reagents / Q000494:pharmacology; D013780:Tetroses / Q000494:pharmacology; D014642:Vanilmandelic Acid / Q000096:biosynthesis; D002721:omega-Chloroacetophenone / Q000037:antagonists & inhibitors / Q000494:pharmacology*
D000447:Aldehydes; D002247:Carbon Isotopes; D004987:Ethers; D006018:Glycols; D008333:Mandelic Acids; D010636:Phenols; D011422:Propionates; D013439:Sulfhydryl Reagents; D013780:Tetroses; D009243:NAD; D014642:Vanilmandelic Acid; D002721:omega-Chloroacetophenone; D010088:Oxidoreductases; D005978:Glutathione; D009638:Norepinephrine