Thalassemic hydrops fetalis in two Chinese-Canadian families.
Two unrelated Chinese-Canadian families with recurrent hydrops fetalis are described. The investigation, acid-base and blood gas studies, and clinical course of one hydropic fetus with large amounts of hemoglobin Bart's who survived for three hours are described. Data for the parents of both families, consistent with the alphathalassemia carrier state, are presented.
D000136:Acid-Base Equilibrium; D044466:Asian People; D002170:Canada; D002245:Carbon Dioxide / Q000097:blood; D002681:China; D004487:Edema / Q000151:congenital*; D004592:Electrophoresis, Starch Gel; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005315:Fetal Diseases / Q000235:genetics*; D005955:Glucosephosphate Dehydrogenase Deficiency; D006452:Hemoglobinometry; D006801:Humans; D002479:Inclusion Bodies; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000235:genetics*; D009996:Osmotic Fragility; D010100:Oxygen / Q000097:blood; D011247:Pregnancy; D013789:Thalassemia / Q000151:congenital / Q000235:genetics*
D002245:Carbon Dioxide; D010100:Oxygen