title: Correlation of messenger RNA function with adenylate-rich segments in the genomes of single-stranded RNA viruses.
abstract: Oligonucleotides enriched in adenylate residues have been demonstrated in the genomes of two positive-strand RNA viruses, Sindbis and Columbia SK. Such oligonucleotides were not found in the genome of vesicular stomatitis virus, a negative-strand virus. The adenylate-rich oligonucleotides from Sindbis and Columbia SK viruses appeared similar when analyzed by zonal sedimentation in sucrose-sodium dodecyl sulfate.
mesh_terms: D000227:Adenine Nucleotides / Q000378:metabolism / Q000502:physiology*; D002499:Centrifugation, Density Gradient; D003090:Coliphages / Q000201:enzymology; D004686:Encephalomyocarditis virus / Q000378:metabolism / Q000502:physiology; D005838:Genotype; D010179:Pancreas / Q000201:enzymology; D011119:Polynucleotides / Q000378:metabolism / Q000502:physiology*; D012328:RNA Viruses / Q000502:physiology*; D012333:RNA, Messenger / Q000378:metabolism / Q000502:physiology*; D012367:RNA, Viral / Q000378:metabolism / Q000502:physiology; D012260:Ribonucleases; D012845:Sindbis Virus / Q000378:metabolism / Q000502:physiology; D014721:Vesicular stomatitis Indiana virus / Q000378:metabolism / Q000502:physiology
chemical_list: D000227:Adenine Nucleotides; D011119:Polynucleotides; D012333:RNA, Messenger; D012367:RNA, Viral; D012260:Ribonucleases