A tumor-associated antigen in human nephroblastomas.
Antisera prepared against extracts of human nephroblastomas (Wilms' tumors) allowed the characterization in these extracts, and in a few extracts of tumors of other organs, of a tumor-associated antigen. This antigen is different from all previously described antigens, and was named W antigen (W for Wilms). It does not seem to be a carcinoembryonic antigen, and hence it could be of viral origin.
D000328:Adult; D000951:Antigens, Neoplasm / Q000032:analysis*; D002648:Child; D005333:Fetus / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D007680:Kidney Neoplasms / Q000276:immunology*; D009396:Wilms Tumor / Q000276:immunology*
D000951:Antigens, Neoplasm