Type C viral expression in primate tissues.
Nucleic acid sequences homologous to a [(3)H]DNA transcript prepared from an endogenous baboon type C virus are readily detected in both the cellular DNA and RNA of several different Old World monkeys. Competitive radioimmunoassays for the major viral protein (p30) of baboon type C viruses detect viral antigen in a normal stumptail spleen and a rhesus ovarian carcinoma. The p30 antigen from these tissues is closely related by several immunologic criteria to the p30 protein of baboon type C viruses. The results indicate that normal primate tissues transcribe endogenous viral-specific RNA and translate at least one viral structural protein.
D000818:Animals; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D000882:Haplorhini; D008251:Macaca; D009374:Neoplasms, Experimental / Q000382:microbiology; D009693:Nucleic Acid Hybridization; D010051:Ovarian Neoplasms / Q000382:microbiology; D010215:Papio; D012367:RNA, Viral / Q000032:analysis*; D011863:Radioimmunoassay; D012190:Retroviridae; D013154:Spleen / Q000382:microbiology; D014158:Transcription, Genetic; D014316:Tritium; D014764:Viral Proteins / Q000032:analysis* / Q000276:immunology
D004279:DNA, Viral; D012367:RNA, Viral; D014764:Viral Proteins; D014316:Tritium