Phosphodiesterases in human tissues. II. Decreased hydrolysis of synthetic substrate by tissues from patients with the Niemann-Pick syndrome.
D000135:Acid Phosphatase / Q000378:metabolism; D001921:Brain / Q000201:enzymology*; D002855:Chromatography, Thin Layer; D005696:Galactosidases / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008099:Liver / Q000201:enzymology*; D008274:Magnesium / Q000494:pharmacology; D009542:Niemann-Pick Diseases / Q000201:enzymology*; D009596:Nitrophenols; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism*; D010761:Phosphorus Radioisotopes; D013109:Sphingomyelins; D013329:Structure-Activity Relationship; D014316:Tritium
D009596:Nitrophenols; D010761:Phosphorus Radioisotopes; D013109:Sphingomyelins; D014316:Tritium; D000135:Acid Phosphatase; D010727:Phosphoric Diester Hydrolases; D005696:Galactosidases; D006026:Glycoside Hydrolases; D008274:Magnesium