Effects of simian virus 40-induced transformation on isoaccepting species of transfer RNA from mouse fibroblasts.
Alterations in isoaccepting species of tRNA in mouse fibroblasts transformed by simian virus 40 were determined for alanine, arginine, histidine, leucine, lysine, phenylalanine, serine, tyrosine, and valine. Significant differences between transformed cells in culture and newborn mouse cells are attributed to tRNA alterations accompanying differentiation of mouse cells.
D000215:Acylation; D000604:Amino Acyl-tRNA Synthetases / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D002250:Carbon Radioisotopes; D002454:Cell Differentiation; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D002478:Cells, Cultured / Q000032:analysis*; D011232:Chemical Precipitation; D002848:Chromatography, DEAE-Cellulose; D002999:Clone Cells; D005347:Fibroblasts / Q000032:analysis; D051379:Mice; D008807:Mice, Inbred BALB C; D010636:Phenols; D012343:RNA, Transfer / Q000032:analysis*; D013539:Simian virus 40 / Q000254:growth & development*; D014316:Tritium
D002250:Carbon Radioisotopes; D010636:Phenols; D014316:Tritium; D012343:RNA, Transfer; D000604:Amino Acyl-tRNA Synthetases