Inhibition of protein kinase and cyclic AMP phosphodiesterase by eritadenine isoamyl ester. A possible mechanism for its biphasic effects on cyclic AMP-dependent lipolysis, steroidogenesis and amino acid uptake.
D000225:Adenine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000273:Adipose Tissue / Q000187:drug effects / Q000201:enzymology* / Q000378:metabolism; D000311:Adrenal Glands / Q000187:drug effects / Q000378:metabolism; D000621:Aminoisobutyric Acids / Q000378:metabolism*; D000818:Animals; D001667:Binding, Competitive; D001692:Biological Transport; D003994:Bucladesine / Q000494:pharmacology; D002250:Carbon Radioisotopes; D000242:Cyclic AMP / Q000378:metabolism / Q000494:pharmacology*; D004822:Epididymis; D004837:Epinephrine / Q000494:pharmacology; D004952:Esters; D006885:Hydroxybutyrates / Q000494:pharmacology; D007700:Kinetics; D008053:Lipid Mobilization / Q000187:drug effects*; D008297:Male; D010726:Phosphodiesterase Inhibitors; D010761:Phosphorus Radioisotopes; D047428:Protein Kinase Inhibitors; D051381:Rats; D013256:Steroids / Q000096:biosynthesis; D013806:Theophylline / Q000494:pharmacology
D000621:Aminoisobutyric Acids; D002250:Carbon Radioisotopes; D004952:Esters; D006885:Hydroxybutyrates; D010726:Phosphodiesterase Inhibitors; D010761:Phosphorus Radioisotopes; D047428:Protein Kinase Inhibitors; D013256:Steroids; D003994:Bucladesine; D013806:Theophylline; D000242:Cyclic AMP; D000225:Adenine; D004837:Epinephrine