Reversible inhibition by hyaluronidase of the insulinotropic action of tolbutamide in isolated hamster pancreatic islets.
D000818:Animals; D002469:Cell Separation; D002478:Cells, Cultured; D006224:Cricetinae; D005947:Glucose / Q000494:pharmacology; D006821:Hyaluronoglucosaminidase / Q000494:pharmacology*; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism*; D003012:Microbial Collagenase; D012636:Secretory Rate / Q000187:drug effects; D013268:Stimulation, Chemical; D014044:Tolbutamide / Q000037:antagonists & inhibitors* / Q000494:pharmacology
D007328:Insulin; D014044:Tolbutamide; D006821:Hyaluronoglucosaminidase; D003012:Microbial Collagenase; D005947:Glucose