The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection.
Areas of cytopathic effect can be circumscribed in cell monolayers by adding antiserum to the liquid nutrient medium after adsorption of virus. This procedure represents a simple and reliable tool for the titration of virus infectivity and provides an experimental model for studying some aspects of virus infection.
D000327:Adsorption; D000362:Agar; D000818:Animals; D002277:Carcinoma; D002460:Cell Line; D002642:Chick Embryo; D046508:Culture Techniques; D003588:Cytopathogenic Effect, Viral; D005069:Evaluation Studies as Topic; D000882:Haplorhini; D006801:Humans; D007106:Immune Sera; D007668:Kidney; D008722:Methods; D009062:Mouth Neoplasms; D009975:Orthomyxoviridae / Q000254:growth & development*; D017955:Poliovirus / Q000254:growth & development*; D011817:Rabbits / Q000276:immunology; D010948:Viral Plaque Assay
D007106:Immune Sera; D000362:Agar