title: Potential antitumor agents. 6. Possible irreversible inhibitors of ribonucleoside diphosphate reductase.
mesh_terms: D000429:Alcohol Oxidoreductases / Q000037:antagonists & inhibitors*; D000478:Alkylation; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000627:therapeutic use; D006528:Carcinoma, Hepatocellular / Q000201:enzymology; D004261:DNA Replication; D004273:DNA, Neoplasm / Q000096:biosynthesis; D005561:Formates / Q000138:chemical synthesis / Q000627:therapeutic use; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000627:therapeutic use; D008113:Liver Neoplasms; D051379:Mice; D009374:Neoplasms, Experimental / Q000201:enzymology; D051381:Rats; D012265:Ribonucleotides; D012510:Sarcoma 180 / Q000188:drug therapy / Q000201:enzymology; D013329:Structure-Activity Relationship; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D005561:Formates; D007546:Isoquinolines; D012265:Ribonucleotides; D013882:Thiosemicarbazones; D000429:Alcohol Oxidoreductases