Mechanism of activation of a cyclic adenosine 3':5'-monophosphate phosphodiesterase from bovine heart by calcium ions. Identification of the protein activator as a Ca2+ binding protein.
D000085:Acetates; D000645:Ammonium Sulfate; D000818:Animals; D001665:Binding Sites; D002118:Calcium; D002127:Calcium Isotopes; D002413:Cations, Divalent; D002417:Cattle; D002498:Centrifugation; D002614:Chelating Agents; D002848:Chromatography, DEAE-Cellulose; D000242:Cyclic AMP; D003956:Dialysis; D004357:Drug Synergism; D004789:Enzyme Activation; D006018:Glycols; D009124:Muscle Proteins / Q000032:analysis / Q000302:isolation & purification*; D009206:Myocardium / Q000032:analysis* / Q000201:enzymology; D009994:Osmolar Concentration; D010726:Phosphodiesterase Inhibitors; D010727:Phosphoric Diester Hydrolases; D011485:Protein Binding
D000085:Acetates; D002127:Calcium Isotopes; D002413:Cations, Divalent; D002614:Chelating Agents; D006018:Glycols; D009124:Muscle Proteins; D010726:Phosphodiesterase Inhibitors; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D000645:Ammonium Sulfate; D002118:Calcium