Inhibitory effects of 2-thiouracil and 2-thiouracil metabolites on enzymes involved in pyrimidine nucleotide biosynthesis.
D000818:Animals; D002250:Carbon Radioisotopes; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors; D066298:In Vitro Techniques; D007700:Kinetics; D051379:Mice; D009713:Nucleotidyltransferases / Q000037:antagonists & inhibitors; D009963:Orotic Acid / Q000378:metabolism; D010430:Pentosyltransferases / Q000037:antagonists & inhibitors; D010770:Phosphotransferases / Q000037:antagonists & inhibitors; D011506:Proteins / Q000032:analysis; D011743:Pyrimidines / Q000096:biosynthesis*; D051381:Rats; D013889:Thiouracil / Q000494:pharmacology*; D013936:Thymidine / Q000378:metabolism; D013941:Thymine / Q000378:metabolism; D014498:Uracil / Q000378:metabolism; D014500:Uracil Nucleotides / Q000096:biosynthesis; D014529:Uridine / Q000378:metabolism
D002250:Carbon Radioisotopes; D011506:Proteins; D011743:Pyrimidines; D014500:Uracil Nucleotides; D014498:Uracil; D013889:Thiouracil; D009963:Orotic Acid; D010430:Pentosyltransferases; D010770:Phosphotransferases; D009713:Nucleotidyltransferases; D002262:Carboxy-Lyases; D013941:Thymine; D013936:Thymidine; D014529:Uridine