Characterization of the active site structures of arginine kinase-substrate complexes. Water proton magnetic relaxation rates and electron paramagnetic resonance spectra of manganous-enzyme complexes with substrates and of a transition state analog.
D000244:Adenosine Diphosphate / Q000378:metabolism*; D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D001120:Arginine / Q000378:metabolism; D001665:Binding Sites; D003402:Creatine Kinase / Q000378:metabolism; D004578:Electron Spin Resonance Spectroscopy; D005561:Formates / Q000494:pharmacology; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008345:Manganese / Q000378:metabolism*; D009132:Muscles / Q000201:enzymology*; D008121:Nephropidae / Q000378:metabolism; D009566:Nitrates / Q000494:pharmacology; D009573:Nitrites / Q000494:pharmacology; D009994:Osmolar Concentration; D010770:Phosphotransferases / Q000378:metabolism*; D011487:Protein Conformation; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013696:Temperature; D013861:Thiocyanates / Q000494:pharmacology; D014867:Water
D005561:Formates; D008024:Ligands; D009566:Nitrates; D009573:Nitrites; D013861:Thiocyanates; D014867:Water; D008345:Manganese; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D001120:Arginine; D010770:Phosphotransferases; D003402:Creatine Kinase