title: Enzyme activated anti-tumour agents. Conjugates of p-hydroxyaniline mustard as substrates for hydrolytic enzymes.
mesh_terms: D000814:Aniline Compounds / Q000378:metabolism; D000816:Aniline Mustard / Q000031:analogs & derivatives; D000818:Animals; D000970:Antineoplastic Agents / Q000378:metabolism*; D002417:Cattle; D005965:Glucuronates / Q000378:metabolism; D005966:Glucuronidase / Q000378:metabolism; D006867:Hydrolases / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000201:enzymology; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008247:Lysosomes / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology; D008974:Mollusca; D009588:Nitrogen Mustard Compounds / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D051381:Rats; D013429:Sulfatases / Q000378:metabolism; D013431:Sulfates / Q000378:metabolism; D014908:Triticum / Q000201:enzymology
chemical_list: D000814:Aniline Compounds; D000970:Antineoplastic Agents; D005965:Glucuronates; D009588:Nitrogen Mustard Compounds; D010710:Phosphates; D013431:Sulfates; C000929:hydroxyaniline mustard; D000816:Aniline Mustard; D006867:Hydrolases; D010744:Phosphoric Monoester Hydrolases; D013429:Sulfatases; D005966:Glucuronidase