title: Adenosine 3':5'-cyclic monophosphate as a regulator of bacterial transformation.
abstract: Adenosine 3':5'-cyclic monophosphate added to exponentially growing cells of Hemophilus influenzae strain Rd increases competence for transformation 100- to 10,000-fold. Cyclic AMP added to near-stationary or stationary cells does not increase competence over the high level normally found in the early stationary phase.
mesh_terms: D000242:Cyclic AMP / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D006193:Haemophilus influenzae / Q000187:drug effects* / Q000254:growth & development; D009675:Novobiocin / Q000494:pharmacology; D013057:Spectrum Analysis; D013307:Streptomycin / Q000494:pharmacology; D013997:Time Factors; D014170:Transformation, Genetic / Q000187:drug effects*
chemical_list: D009675:Novobiocin; D000242:Cyclic AMP; D013307:Streptomycin