Adenylate cyclase activity in fibroblasts transformed by Kirsten or Moloney sarcoma viruses. Decreased activity and loss of response to prostaglandin E1.
D000255:Adenosine Triphosphate; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D004789:Enzyme Activation / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects / Q000201:enzymology*; D006160:Guanosine Triphosphate / Q000494:pharmacology; D007668:Kidney; D007700:Kinetics; D009052:Leukemia Virus, Murine / Q000187:drug effects / Q000201:enzymology; D008274:Magnesium / Q000494:pharmacology; D008345:Manganese / Q000494:pharmacology; D008979:Moloney murine leukemia virus / Q000187:drug effects / Q000201:enzymology*; D010761:Phosphorus Radioisotopes; D011453:Prostaglandins / Q000494:pharmacology*; D011485:Protein Binding; D051381:Rats; D013045:Species Specificity; D013997:Time Factors
D010761:Phosphorus Radioisotopes; D011453:Prostaglandins; D008345:Manganese; D006160:Guanosine Triphosphate; D000255:Adenosine Triphosphate; D000262:Adenylyl Cyclases; D008274:Magnesium