Inability to detect hepatitis B virus or specific antigens in transformed chimpanzee lymphocytes.
Transformed chimpanzee lymphocytes were examined to determine whether they would support the replication of hepatitis B virus. After 5 months, no hepatitis B virus, hepatitis B surface antigen, or antibody to hepatitis B surface antigen was detected.
D000818:Animals; D002353:Carrier State; D002478:Cells, Cultured; D003168:Complement Fixation Tests; D005455:Fluorescent Antibody Technique; D006509:Hepatitis B / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000032:analysis; D006511:Hepatitis B Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000276:immunology*; D004854:Herpesvirus 4, Human / Q000276:immunology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D002679:Pan troglodytes; D011863:Radioimmunoassay; D014779:Virus Replication
D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens