The biological activity and the binding affinity of modified insulins determined on isolated rat fat cells.
D000273:Adipose Tissue / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D004305:Dose-Response Relationship, Drug; D005947:Glucose / Q000378:metabolism; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D007329:Insulin Antagonists; D007457:Iodine Radioisotopes; D008055:Lipids / Q000096:biosynthesis; D011485:Protein Binding; D051381:Rats; D011956:Receptors, Cell Surface; D013329:Structure-Activity Relationship
D007328:Insulin; D007329:Insulin Antagonists; D007457:Iodine Radioisotopes; D008055:Lipids; D011956:Receptors, Cell Surface; D005947:Glucose