Radioreceptor assay of human chorionic gonadotropin: detection of early pregnancy.
A rapid, sensitive, and specific radioreceptor assay for the determination of human chorionic gonadotropin and luteinizing hormone in plasma is described. Plasma membranes of bovine corpora lutea of early pregnancy, which bind biologically active labeled human chorionic gonadotropin, have been used as receptor. Pregnancy could be detected by assaying the gonadotropin in plasma samples obtained from day 6 to 8 after conception.
D000172:Acromegaly / Q000097:blood; D000818:Animals; D002417:Cattle; D006063:Chorionic Gonadotropin / Q000097:blood*; D003338:Corpus Luteum / Q000378:metabolism; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood; D007774:Lactation; D007986:Luteinizing Hormone / Q000097:blood; D008598:Menstruation; D011247:Pregnancy; D011258:Pregnancy Tests; D011869:Radioligand Assay; D011956:Receptors, Cell Surface; D013997:Time Factors
D006063:Chorionic Gonadotropin; D011956:Receptors, Cell Surface; D007986:Luteinizing Hormone