title: Enzyme catalysis: conflicting requirements of substrate access and transition state affinity.
mesh_terms: D000249:Adenosine Monophosphate; D001665:Binding Sites; D002384:Catalysis; D003574:Cytochrome c Group; D003576:Electron Transport Complex IV / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism*; D005649:Fumarate Hydratase / Q000378:metabolism; D007535:Isomerases / Q000378:metabolism; D007664:Ketosteroids; D007700:Kinetics; D008190:Lyases / Q000378:metabolism; D008293:Malates; D008954:Models, Biological; D011485:Protein Binding; D013386:Succinates; D013482:Superoxide Dismutase
chemical_list: D003574:Cytochrome c Group; D004798:Enzymes; D007664:Ketosteroids; D008293:Malates; D013386:Succinates; D000249:Adenosine Monophosphate; D013482:Superoxide Dismutase; D003576:Electron Transport Complex IV; D008190:Lyases; D005649:Fumarate Hydratase; D007535:Isomerases