Intracellular hydroxylation of non-helical protocollagen to form triple-helical procollagen and subsequent secretion of the molecule.
D000693:Anaerobiosis; D000818:Animals; D002250:Carbon Radioisotopes; D002642:Chick Embryo; D002850:Chromatography, Gel; D002918:Chymotrypsin; D003094:Collagen / Q000096:biosynthesis / Q000378:metabolism*; D003513:Cycloheximide / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D006909:Hydroxyproline / Q000096:biosynthesis; D010434:Pepsin A; D011393:Procollagen-Proline Dioxygenase / Q000378:metabolism; D011487:Protein Conformation; D011498:Protein Precursors; D011725:Pyridines / Q000494:pharmacology; D013696:Temperature; D013710:Tendons / Q000187:drug effects / Q000378:metabolism; D013997:Time Factors
D002250:Carbon Radioisotopes; D011498:Protein Precursors; D011725:Pyridines; D003094:Collagen; D003513:Cycloheximide; D011393:Procollagen-Proline Dioxygenase; D002918:Chymotrypsin; D010434:Pepsin A; D006909:Hydroxyproline