Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)-enolide 3-acetate (AY-17,605) and structurally related compounds.
D000818:Animals; D001921:Brain / Q000201:enzymology*; D002297:Cardanolides / Q000494:pharmacology*; D002298:Cardenolides; D002301:Cardiac Glycosides / Q000494:pharmacology; D002417:Cattle; D000242:Cyclic AMP; D004074:Digitoxin / Q000494:pharmacology; D004912:Erythrocytes / Q000201:enzymology; D005947:Glucose / Q000494:pharmacology; D006914:Hydroxysteroids / Q000494:pharmacology; D066298:In Vitro Techniques; D009206:Myocardium / Q000201:enzymology*; D010726:Phosphodiesterase Inhibitors; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D051381:Rats; D013806:Theophylline / Q000494:pharmacology
D002297:Cardanolides; D002298:Cardenolides; D002301:Cardiac Glycosides; D006914:Hydroxysteroids; D010726:Phosphodiesterase Inhibitors; C006259:AY 17,605; D013806:Theophylline; D000242:Cyclic AMP; D004074:Digitoxin; D010727:Phosphoric Diester Hydrolases; D005947:Glucose