Sleep induced by small doses of tubocurarine injected into cerebral ventricles of dog.
In unanaesthetized dogs, sleep with the typical sleep pattern in the E.E.G. was produced with (+)-tubocurarine when injected in a small dose (500 ng) into, or perfused in low concentration (100 ng/ml) through the cerebral ventricles.
D000818:Animals; D002552:Cerebral Ventricles; D004285:Dogs; D004569:Electroencephalography; D005260:Female; D007267:Injections; D008297:Male; D010477:Perfusion; D012890:Sleep / Q000187:drug effects*; D012895:Sleep, REM / Q000187:drug effects; D014403:Tubocurarine / Q000494:pharmacology*
D014403:Tubocurarine