Phosphorylation of myelin basic protein by an adenosine 3':5'-cyclic monophosphate-dependent protein kinase.
Myelin basic protein was shown to be a substrate for protein kinase from rabbit muscle. One of the major sites of phosphorylation was the serine residue in the sequence Gly-Arg-Gly-Leu-Ser-Leu. The arginine residue in this sequence is known to be a substrate for a protein methylase.
D000818:Animals; D001120:Arginine; D000242:Cyclic AMP / Q000378:metabolism; D005998:Glycine; D007930:Leucine; D009132:Muscles / Q000201:enzymology; D009186:Myelin Sheath; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*; D011817:Rabbits; D012694:Serine
D009419:Nerve Tissue Proteins; D012694:Serine; D001120:Arginine; D000242:Cyclic AMP; D011494:Protein Kinases; D007930:Leucine; D005998:Glycine