Stimulation of H-3-leucine incorporation into the proinsulin and insulin fraction of isolated pancreatic mouse islets in the presence of glucagon, theophylline and cyclic AMP.
D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D046508:Culture Techniques; D000242:Cyclic AMP / Q000494:pharmacology*; D005934:Glucagon / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology; D007328:Insulin / Q000096:biosynthesis / Q000378:metabolism*; D007515:Islets of Langerhans / Q000378:metabolism*; D007930:Leucine / Q000378:metabolism*; D008297:Male; D051379:Mice; D011384:Proinsulin / Q000378:metabolism*; D013806:Theophylline / Q000494:pharmacology*; D014316:Tritium
D007328:Insulin; D014316:Tritium; D005934:Glucagon; D011384:Proinsulin; D013806:Theophylline; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D007930:Leucine; D005947:Glucose