Mutant of polyoma virus with impaired adsorption to BHK cells.
A mutant of polyoma virus PY235 has an impaired adsorption to guinea pig red blood cells and BHK-21 hamster cells. Adsorption to 3T3 mouse cells is much less inhibited. These altered adsorption properties are responsible for the apparent inability of PY235 to cause cell transformation or hemagglutination.
D000327:Adsorption; D000818:Animals; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D006224:Cricetinae; D004912:Erythrocytes; D005347:Fibroblasts; D006168:Guinea Pigs; D006386:Hemagglutination Tests; D006863:Hydrogen-Ion Concentration; D007668:Kidney; D051379:Mice; D008815:Mice, Inbred Strains / Q000196:embryology; D009154:Mutation; D011120:Polyomavirus; D013696:Temperature; D010948:Viral Plaque Assay