Interaction between polyuridylic acid and rabbit globin messenger ribonucleic acid.
Poly(U) binds to globin mRNA in 0.1m-NaCl. Studies with ribonuclease digestion of this complex suggest that there are polyadenylate-rich sequences in the mRNA containing about 30-40 adenylate residues. The sequences appear to be homogenous and of approximately the same length for both alpha- and beta-globin mRNA. They are most likely located at the 3' terminus of the molecule.
D000818:Animals; D001665:Binding Sites; D002247:Carbon Isotopes; D002499:Centrifugation, Density Gradient; D004591:Electrophoresis, Polyacrylamide Gel; D005914:Globins; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000032:analysis; D010179:Pancreas; D010727:Phosphoric Diester Hydrolases; D011072:Poly U; D011119:Polynucleotides; D012333:RNA, Messenger; D051381:Rats; D012156:Reticulocytes; D012260:Ribonucleases; D012911:Snakes; D013056:Spectrophotometry, Ultraviolet; D013154:Spleen; D013696:Temperature; D013997:Time Factors; D014316:Tritium; D014688:Venoms
D002247:Carbon Isotopes; D009841:Oligonucleotides; D011119:Polynucleotides; D012333:RNA, Messenger; D014688:Venoms; D014316:Tritium; D011072:Poly U; D005914:Globins; D012260:Ribonucleases; D010727:Phosphoric Diester Hydrolases