title: Differentiation of smallpox and camelpox viruses in cultures of human and monkey cells.
abstract: The cytopathic effect of smallpox and camelpox viruses has been compared in cell cultures derived from human and monkey tissues. The two viruses could easily be distinguished in HeLa, GMK-AH1, BSC-1 and WISH cells, camelpox producing multinucleate giant cells and smallpox producing rounding up of individual cells. In other cells (LLC-MK2, HEK and 2RhK) the differences were not so marked, and in some (VERO, HEL, K and HuTh) no differences were seen.
mesh_terms: D000650:Amnion; D000818:Animals; D002162:Camelus; D002460:Cell Line; D002478:Cells, Cultured; D003588:Cytopathogenic Effect, Viral; D003937:Diagnosis, Differential; D005260:Female; D000882:Haplorhini; D006367:HeLa Cells; D006801:Humans; D007668:Kidney; D008168:Lung; D011212:Poxviridae / Q000145:classification*; D013961:Thyroid Gland; D002583:Uterine Cervical Neoplasms; D012901:Variola virus / Q000145:classification*