title: Improved technique for the isolation of temperature-sensitive mutants of foot-and-mouth disease virus.
abstract: An improved temperature-shift selection and screening method is described for the isolation of temperature-sensitive mutants of foot and mouth disease virus.
mesh_terms: D000818:Animals; D005537:Aphthovirus / Q000254:growth & development / Q000302:isolation & purification*; D002460:Cell Line; D006224:Cricetinae; D007668:Kidney; D008722:Methods; D009154:Mutation; D013696:Temperature; D014776:Virus Cultivation; D014779:Virus Replication