Bases methylated in vitro by cell-free extracts of adenovirus-18-induced tumours.
The tRNA methylase activity in vitro of adenovirus-18-induced tumour was studied. The activity expressed per mg of protein was the same for extracts of tumours induced by either adenovirus-12 or adenovirus-18. The methylated bases isolated after incubation with extract from adenovirus-18-induced tumour were N(1)-methylguanine, 1-methyladenine, 3-methyladenine and N(6)-methyladenine.
D000225:Adenine / Q000378:metabolism; D000257:Adenoviridae Infections / Q000201:enzymology*; D000818:Animals; D002474:Cell-Free System; D002854:Chromatography, Paper; D006224:Cricetinae; D004926:Escherichia coli; D006147:Guanine / Q000378:metabolism; D008745:Methylation; D008780:Methyltransferases / Q000378:metabolism*; D009374:Neoplasms, Experimental / Q000201:enzymology*; D012329:RNA, Bacterial; D012343:RNA, Transfer / Q000032:analysis; D014412:Tumor Virus Infections / Q000201:enzymology*
D012329:RNA, Bacterial; D006147:Guanine; D012343:RNA, Transfer; D008780:Methyltransferases; D000225:Adenine