Evidence against formation of a pyrophosphoryl enzyme intermediate in the phosphoribosylpyrophosphate synthetase reaction.
D000244:Adenosine Diphosphate; D000249:Adenosine Monophosphate; D000255:Adenosine Triphosphate; D001665:Binding Sites; D002250:Carbon Radioisotopes; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D002854:Chromatography, Paper; D011756:Diphosphates; D006593:Hexokinase; D007553:Isotope Labeling; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy; D008722:Methods; D010428:Pentosephosphates / Q000138:chemical synthesis; D010756:Phosphoric Acids; D010761:Phosphorus Radioisotopes; D010770:Phosphotransferases / Q000378:metabolism*; D011485:Protein Binding; D011770:Pyruvate Kinase; D012486:Salmonella typhimurium / Q000201:enzymology; D013329:Structure-Activity Relationship
D002250:Carbon Radioisotopes; D011756:Diphosphates; D010428:Pentosephosphates; D010756:Phosphoric Acids; D010761:Phosphorus Radioisotopes; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate; D010770:Phosphotransferases; D006593:Hexokinase; D011770:Pyruvate Kinase