Isolation of a neurotropic type C virus.
A neurogenic paralysis of the lower limb can be induced and serially transmitted in mice by a nontransforming type C virus strain that originated in an embryo of a wild mouse. The virus exerted a neurotropic effect on the anterior horn neurons.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001921:Brain / Q000276:immunology; D002478:Cells, Cultured; D003168:Complement Fixation Tests; D004622:Embryo, Mammalian / Q000382:microbiology; D006614:Hindlimb; D008223:Lymphoma / Q000209:etiology; D051379:Mice; D009132:Muscles / Q000276:immunology; D009858:Oncogenic Viruses / Q000302:isolation & purification*; D010243:Paralysis / Q000209:etiology* / Q000276:immunology; D012328:RNA Viruses / Q000302:isolation & purification*; D012190:Retroviridae / Q000254:growth & development / Q000276:immunology / Q000302:isolation & purification; D013116:Spinal Cord / Q000276:immunology; D013154:Spleen / Q000276:immunology
D000956:Antigens, Viral