Synthesis of type 2 adenovirus DNA in the presence of cycloheximide.
Adenovirus type 2 DNA synthesis, either in permissive human cells or nonpermissive monkey cells, becomes independent of protein synthesis after the appearance of progeny viral DNA. In the presence of cycloheximide, semiconservative replication and initiation of progeny molecules can occur.
D000256:Adenoviridae / Q000254:growth & development / Q000378:metabolism*; D000818:Animals; D002460:Cell Line; D002499:Centrifugation, Density Gradient; D003513:Cycloheximide / Q000494:pharmacology*; D004247:DNA / Q000096:biosynthesis; D004261:DNA Replication; D004279:DNA, Viral / Q000096:biosynthesis*; D000882:Haplorhini; D006367:HeLa Cells / Q000378:metabolism; D006801:Humans; D007668:Kidney; D009693:Nucleic Acid Hybridization; D014176:Protein Biosynthesis; D011691:Puromycin / Q000494:pharmacology; D012703:Serotyping; D013539:Simian virus 40 / Q000254:growth & development / Q000378:metabolism; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014316:Tritium; D014779:Virus Replication / Q000187:drug effects*
D004279:DNA, Viral; D014316:Tritium; D011691:Puromycin; D004247:DNA; D003513:Cycloheximide; D013936:Thymidine