Thymus adenylate cyclase activity during murine leukemogenesis.
Activity of thymus adenylate cyclase was more than three times higher in leukemic AKR mice than in nonleukemic AKR mice and CBA mice. Preleukemic AKR mice that had no evidence of leukemia but were expected to soon develop the disease exhibited similarly elevated activities of thymus adenylate cyclase.
D000255:Adenosine Triphosphate / Q000378:metabolism; D000262:Adenylyl Cyclases / Q000378:metabolism*; D000367:Age Factors; D000818:Animals; D000242:Cyclic AMP / Q000096:biosynthesis; D004789:Enzyme Activation; D004837:Epinephrine / Q000494:pharmacology; D007945:Leukemia, Lymphoid / Q000201:enzymology* / Q000473:pathology; D051379:Mice; D008806:Mice, Inbred AKR; D008808:Mice, Inbred CBA; D010761:Phosphorus Radioisotopes; D013268:Stimulation, Chemical; D013950:Thymus Gland / Q000201:enzymology* / Q000473:pathology
D010761:Phosphorus Radioisotopes; D000255:Adenosine Triphosphate; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D004837:Epinephrine