Insulin degradation in insulinoma: evidence for the occurrence of an inactive form of glutathione-insulin transhydrogenase and for the absence of insulin A and B chains degrading protease(s).
D007516:Adenoma, Islet Cell / Q000201:enzymology*; D000328:Adult; D000818:Animals; D002850:Chromatography, Gel; D004492:Edetic Acid / Q000494:pharmacology; D005978:Glutathione / Q000494:pharmacology; D005980:Glutathione Reductase / Q000378:metabolism*; D006801:Humans; D007106:Immune Sera; D005779:Immunodiffusion; D007328:Insulin / Q000378:metabolism*; D007457:Iodine Radioisotopes; D007700:Kinetics; D008970:Molecular Weight; D009363:Neoplasm Proteins / Q000378:metabolism; D010088:Oxidoreductases / Q000276:immunology; D010446:Peptide Fragments; D011384:Proinsulin / Q000096:biosynthesis; D011817:Rabbits / Q000276:immunology
D007106:Immune Sera; D007328:Insulin; D007457:Iodine Radioisotopes; D009363:Neoplasm Proteins; D010446:Peptide Fragments; D011384:Proinsulin; D004492:Edetic Acid; D010088:Oxidoreductases; D005980:Glutathione Reductase; D005978:Glutathione