title: The plaque-antiserum method: an assay of virus infectivity and an experimental model of virus infection.
abstract: Areas of cytopathic effect can be circumscribed in cell monolayers by adding antiserum to the liquid nutrient medium after adsorption of virus. This procedure represents a simple and reliable tool for the titration of virus infectivity and provides an experimental model for studying some aspects of virus infection.
mesh_terms: D000327:Adsorption; D000362:Agar; D000818:Animals; D002277:Carcinoma; D002460:Cell Line; D002642:Chick Embryo; D046508:Culture Techniques; D003588:Cytopathogenic Effect, Viral; D005069:Evaluation Studies as Topic; D000882:Haplorhini; D006801:Humans; D007106:Immune Sera; D007668:Kidney; D008722:Methods; D009062:Mouth Neoplasms; D009975:Orthomyxoviridae / Q000254:growth & development*; D017955:Poliovirus / Q000254:growth & development*; D011817:Rabbits / Q000276:immunology; D010948:Viral Plaque Assay
chemical_list: D007106:Immune Sera; D000362:Agar