Smooth muscle autoantibodies in infectious mononucleosis.
Smooth muscle antibodies (S.M.A.) were found in the sera of 81% of 126 patients over 10 years old with seropositive infectious mononucleosis tested within one month of onset. In 27 patients presenting clinically with infectious mononucleosis but having negative Paul-Bunnell tests the incidence of S.M.A. was 44%. In children 10 years of age or less in these two categories S.M.A. were present in 75% and 25% respectively, while in children of similar age not suspected of having infectious mononucleosis the incidence of S.M.A. was 10%. Among 45 adults with past histories of seropositive infectious mononucleosis more than one year before the incidence of S.M.A. was 33%, in contrast to 14% in 98 subjects with a negative history for infectious mononucleosis.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000032:analysis; D001323:Autoantibodies / Q000032:analysis*; D002648:Child; D005260:Female; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M; D007244:Infectious Mononucleosis / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000276:immunology*; D012698:Serologic Tests; D013997:Time Factors
D000914:Antibodies, Viral; D001323:Autoantibodies; D007075:Immunoglobulin M