Use of the asparagine auxotroph of the L5178Y murine leukemia for the detection of chemical mutagens in vitro and in the host-mediated assay.
D000166:Acridines / Q000633:toxicity; D000477:Alkylating Agents / Q000633:toxicity; D000818:Animals; D001216:Asparagine; D001372:Aza Compounds / Q000633:toxicity; D002460:Cell Line; D002478:Cells, Cultured; D002999:Clone Cells; D003470:Culture Media; D005821:Genetic Techniques; D007938:Leukemia; D008025:Ligases / Q000032:analysis; D008297:Male; D008698:Mesylates / Q000633:toxicity; D051379:Mice; D008815:Mice, Inbred Strains; D009153:Mutagens; D009154:Mutation / Q000187:drug effects*; D009588:Nitrogen Mustard Compounds / Q000633:toxicity; D009602:Nitrosamines / Q000633:toxicity; D009604:Nitrosoguanidines / Q000633:toxicity
D000166:Acridines; D000477:Alkylating Agents; D001372:Aza Compounds; D003470:Culture Media; D008698:Mesylates; D009153:Mutagens; D009588:Nitrogen Mustard Compounds; D009602:Nitrosamines; D009604:Nitrosoguanidines; D001216:Asparagine; D008025:Ligases