title: Acidophilic adenoma of the pituitary with polyneuropathy.
abstract: An acromegalic man aged 70 developed progressive polyneuropathy affecting mainly the extremities. The peripheral nerves showed hypertrophic neuropathy and accumulation of acid mucopolysaccharides in the nerve without `onion bulb' formation. The myelin showed a lamellar disintegration and vesicular formation. It is suggested that the association of these findings represents a pathological entity, acromegalic polyneuropathy.
mesh_terms: D000172:Acromegaly / Q000209:etiology*; D000239:Adenoma, Acidophil / Q000150:complications*; D000368:Aged; D003711:Demyelinating Diseases; D004558:Electric Stimulation; D005071:Evoked Potentials; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009132:Muscles / Q000503:physiopathology; D009186:Myelin Sheath; D010525:Peripheral Nerves / Q000473:pathology / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D010911:Pituitary Neoplasms / Q000150:complications*