The essential role of the imidazole group of glucagon in its biological function.
D000107:Acetylation; D000262:Adenylyl Cyclases / Q000032:analysis; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000242:Cyclic AMP / Q000096:biosynthesis; D004789:Enzyme Activation / Q000187:drug effects; D005461:Fluorine; D005934:Glucagon / Q000032:analysis / Q000378:metabolism*; D006146:Guanidines; D006639:Histidine / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007093:Imidazoles / Q000378:metabolism*; D008099:Liver / Q000201:enzymology; D008239:Lysine / Q000032:analysis; D009578:Nitrobenzenes; D010455:Peptides; D051381:Rats; D013329:Structure-Activity Relationship
D000596:Amino Acids; D006146:Guanidines; D007093:Imidazoles; D009578:Nitrobenzenes; D010455:Peptides; D005461:Fluorine; D006639:Histidine; D005934:Glucagon; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D008239:Lysine