The effect of repeated vaccination in an enzootic foot-and-mouth disease area on the incidence of virus carrier cattle.
A comparison was made of the incidence of foot-and-mouth disease virus ;carrier' cattle in an unvaccinated enzootic area and an area where routine 6-monthly vaccination with an inactivated vaccine had been carried out for 3-4 years. The incidence of carriers in the vaccinated area was 0.49% as compared to 3.34% in the non-vaccinated area. The results indicate that, provided the immune status of the vaccinated herd is maintained at a level sufficient to prevent outbreaks of clinical disease and the re-introduction of virus is prevented through livestock movement controls, it should be possible to eradicate the disease from an enzootic area through vaccination.
D000818:Animals; D000914:Antibodies, Viral / Q000302:isolation & purification; D000956:Antigens, Viral / Q000302:isolation & purification; D005537:Aphthovirus / Q000302:isolation & purification; D002353:Carrier State; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000517:prevention & control; D003588:Cytopathogenic Effect, Viral; D005536:Foot-and-Mouth Disease / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D007630:Kenya; D008221:Lymphoid Tissue / Q000382:microbiology; D008297:Male; D010614:Pharynx / Q000382:microbiology; D011790:Quarantine; D012698:Serologic Tests / Q000379:methods; D014611:Vaccination; D014776:Virus Cultivation
D000914:Antibodies, Viral; D000956:Antigens, Viral