Human cytomegalovirus. II. Lack of relatedness to DNA of herpes simples I and II, Epstein-Barr virus, and nonhuman strains of cytomegalovirus.
The purified DNA of human cytomegalovirus, radiolabeled in vitro, was examined for homology to Epstein-Barr virus, herpes simplex type I and II, and simian and murine cytomegalovirus DNA by DNA-DNA reassociation kinetics analyses with the S1 enzyme differential digestion technique. Cross-matching of the DNAs showed no relatedness or less than 5% detectable homology.
D001230:Aspergillus / Q000201:enzymology; D003587:Cytomegalovirus / Q000032:analysis*; D004279:DNA, Viral / Q000032:analysis*; D004720:Endonucleases; D004854:Herpesvirus 4, Human / Q000032:analysis*; D009691:Nucleic Acid Denaturation; D009693:Nucleic Acid Hybridization; D009695:Nucleic Acid Renaturation; D018139:Simplexvirus / Q000032:analysis*
D004279:DNA, Viral; D004720:Endonucleases