title: A predictable modification of enzyme specificity. Selective alteration of DNA bases by metal ions to promote cleavage specificity by deoxyribonuclease.
mesh_terms: D000225:Adenine / Q000032:analysis; D000469:Alkaline Phosphatase; D000818:Animals; D001665:Binding Sites; D002417:Cattle; D003300:Copper / Q000494:pharmacology*; D003596:Cytosine / Q000032:analysis; D004247:DNA; D003851:Deoxyribonucleases / Q000378:metabolism*; D006147:Guanine / Q000032:analysis; D008274:Magnesium / Q000494:pharmacology*; D008628:Mercury / Q000494:pharmacology*; D009690:Nucleic Acid Conformation; D010727:Phosphoric Diester Hydrolases; D013941:Thymine / Q000032:analysis; D013950:Thymus Gland / Q000201:enzymology
chemical_list: D006147:Guanine; D003300:Copper; D003596:Cytosine; D004247:DNA; D003851:Deoxyribonucleases; D000469:Alkaline Phosphatase; D010727:Phosphoric Diester Hydrolases; D008628:Mercury; D008274:Magnesium; D000225:Adenine; D013941:Thymine