The fructose 1,6-diphosphatase-phosphofructokinase substrate cycle. A site of regulation of hepatic gluconeogenesis by glucagon.
D000818:Animals; D002250:Carbon Radioisotopes; D000242:Cyclic AMP / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006597:Fructose-Bisphosphatase / Q000378:metabolism*; D005636:Fructosephosphates / Q000378:metabolism; D005934:Glucagon / Q000494:pharmacology*; D005943:Gluconeogenesis / Q000187:drug effects*; D005947:Glucose / Q000008:administration & dosage / Q000378:metabolism; D007700:Kinetics; D007773:Lactates / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D008956:Models, Chemical; D009097:Multienzyme Complexes / Q000378:metabolism; D010477:Perfusion; D010710:Phosphates / Q000378:metabolism; D010732:Phosphofructokinase-1 / Q000378:metabolism*; D011773:Pyruvates / Q000378:metabolism; D051381:Rats; D013329:Structure-Activity Relationship; D014316:Tritium
D002250:Carbon Radioisotopes; D005636:Fructosephosphates; D007773:Lactates; D009097:Multienzyme Complexes; D010710:Phosphates; D011773:Pyruvates; D014316:Tritium; D005934:Glucagon; D000242:Cyclic AMP; D010732:Phosphofructokinase-1; D006597:Fructose-Bisphosphatase; D005947:Glucose