title: 6-Substituted 5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-ones with hypotensive activity.
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D001993:Bronchodilator Agents / Q000138:chemical synthesis / Q000494:pharmacology; D002417:Cattle; D000242:Cyclic AMP; D004285:Dogs; D007093:Imidazoles / Q000138:chemical synthesis / Q000494:pharmacology; D009206:Myocardium / Q000201:enzymology; D010726:Phosphodiesterase Inhibitors; D011719:Pyrazines / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000959:Antihypertensive Agents; D001993:Bronchodilator Agents; D007093:Imidazoles; D010726:Phosphodiesterase Inhibitors; D011719:Pyrazines; C004974:5-chloro-1,3-dihydro-2H-imidazo(4,5-b)pyrazin-2-one; D000242:Cyclic AMP