Ectopic production of human chorionic gonadotrophin by human breast tumours.
The incidence of tumours ectopically producing the human chorionic gonadotrophins was studied in patients with breast cancer. Specific radioimmunoassay of subunits of HCG was utilized. Nine out of 65 patients with carcinoma of breast showed the presence of circulating HCG. Patients with other pathological conditions of breast tissue did not show any evidence of circulating HCG.
D000232:Adenofibroma / Q000378:metabolism; D000328:Adult; D001943:Breast Neoplasms / Q000378:metabolism*; D002277:Carcinoma / Q000378:metabolism; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000378:metabolism; D006063:Chorionic Gonadotropin / Q000096:biosynthesis*; D005260:Female; D006729:Hormones, Ectopic / Q000096:biosynthesis*; D006801:Humans; D007106:Immune Sera; D007457:Iodine Radioisotopes; D008413:Mastitis / Q000378:metabolism; D008593:Menopause; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009384:Paraneoplastic Endocrine Syndromes; D011247:Pregnancy; D011863:Radioimmunoassay
D006063:Chorionic Gonadotropin; D006729:Hormones, Ectopic; D007106:Immune Sera; D007457:Iodine Radioisotopes