title: Hemagglutination-inhibition: rapid assay for neuraminic acid-containing viruses.
abstract: Influenza virus particles bind rapidly to vesicular stomatitis, Sindbis, or Rauscher murine leukemia virus particles, forming mixed aggregates demonstrable by electron microscopy. The normal hemagglutinating property of influenza virus is inhibited by these viruses, providing a rapid quantitative assay. Prior treatment with neuraminidase blocks the ability of other viruses to inhibit influenza virus hemagglutination.
mesh_terms: D000818:Animals; D001666:Binding Sites, Antibody; D002460:Cell Line; D006224:Cricetinae; D005069:Evaluation Studies as Topic; D006023:Glycoproteins / Q000032:analysis; D006385:Hemagglutination Inhibition Tests / Q000379:methods; D006389:Hemagglutinins, Viral; D007668:Kidney; D051379:Mice; D008854:Microscopy, Electron; D009438:Neuraminic Acids / Q000032:analysis; D009975:Orthomyxoviridae / Q000276:immunology; D011925:Rauscher Virus / Q000032:analysis / Q000302:isolation & purification*; D018108:Respirovirus / Q000276:immunology; D012845:Sindbis Virus / Q000032:analysis / Q000302:isolation & purification*; D014721:Vesicular stomatitis Indiana virus / Q000032:analysis / Q000302:isolation & purification*; D014764:Viral Proteins / Q000032:analysis
chemical_list: D006023:Glycoproteins; D006389:Hemagglutinins, Viral; D009438:Neuraminic Acids; D014764:Viral Proteins