Alterations of rat liver lysosomes and smooth endoplasmic reticulum induced by the diazafluoranthen derivative AC-3579. I. Morphologic and biochemical lesions.
D000818:Animals; D001372:Aza Compounds / Q000494:pharmacology; D001835:Body Weight / Q000187:drug effects; D002784:Cholesterol / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000187:drug effects*; D005449:Fluorenes; D005952:Glucose-6-Phosphatase / Q000378:metabolism; D006017:Glycolipids / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism / Q000473:pathology; D008112:Liver Glycogen / Q000378:metabolism; D008247:Lysosomes / Q000187:drug effects*; D008297:Male; D008854:Microscopy, Electron; D009696:Nucleic Acids / Q000378:metabolism; D009708:Nucleotidases / Q000378:metabolism; D009929:Organ Size; D010743:Phospholipids / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D001372:Aza Compounds; D005449:Fluorenes; D006017:Glycolipids; D006993:Hypnotics and Sedatives; D008112:Liver Glycogen; D009696:Nucleic Acids; D010743:Phospholipids; D011506:Proteins; C006177:2-(4'-methylpiperazino-1-methyl)-1,3-diazafluoranthene 1-oxide; D002784:Cholesterol; D009708:Nucleotidases; D010744:Phosphoric Monoester Hydrolases; D005952:Glucose-6-Phosphatase; D006026:Glycoside Hydrolases