A high susceptibility of Fanconi's anemia to chromosome breakage by DNA cross-linking agents.
D000476:Alkanesulfonates / Q000494:pharmacology; D000477:Alkylating Agents / Q000494:pharmacology*; D000741:Anemia, Aplastic / Q000235:genetics*; D000963:Antimetabolites / Q000494:pharmacology*; D002110:Caffeine / Q000494:pharmacology; D002455:Cell Division; D002478:Cells, Cultured; D002701:Chloramphenicol / Q000494:pharmacology; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects* / Q000528:radiation effects; D003036:Cobalt Isotopes; D004260:DNA Repair; D003609:Dactinomycin / Q000494:pharmacology; D006801:Humans; D008214:Lymphocytes / Q000166:cytology; D008466:Mechlorethamine / Q000494:pharmacology; D008730:Methoxsalen / Q000494:pharmacology; D008937:Mitomycins / Q000494:pharmacology; D009604:Nitrosoguanidines / Q000494:pharmacology; D011804:Quinolines / Q000494:pharmacology; D011830:Radiation Effects; D014466:Ultraviolet Rays
D000476:Alkanesulfonates; D000477:Alkylating Agents; D000963:Antimetabolites; D003036:Cobalt Isotopes; D008937:Mitomycins; D009604:Nitrosoguanidines; D011804:Quinolines; D003609:Dactinomycin; D002110:Caffeine; D008466:Mechlorethamine; D002701:Chloramphenicol; D008730:Methoxsalen