title: Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme.
mesh_terms: D002482:Cellulose; D002848:Chromatography, DEAE-Cellulose; D004586:Electrophoresis; D004912:Erythrocytes / Q000201:enzymology*; D005069:Evaluation Studies as Topic; D006073:Gout / Q000097:blood / Q000201:enzymology*; D006461:Hemolysis; D006801:Humans; D007202:Indicators and Reagents; D007926:Lesch-Nyhan Syndrome / Q000097:blood / Q000201:enzymology; D008064:Lipidoses / Q000097:blood / Q000201:enzymology; D008722:Methods; D010428:Pentosephosphates; D010756:Phosphoric Acids; D010761:Phosphorus Radioisotopes; D010770:Phosphotransferases / Q000097:blood* / Q000302:isolation & purification; D011686:Purine-Pyrimidine Metabolism, Inborn Errors / Q000097:blood / Q000201:enzymology*; D014527:Uric Acid / Q000097:blood / Q000378:metabolism*
chemical_list: D007202:Indicators and Reagents; D010428:Pentosephosphates; D010756:Phosphoric Acids; D010761:Phosphorus Radioisotopes; D014527:Uric Acid; D002482:Cellulose; D010770:Phosphotransferases