Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.
D000429:Alcohol Oxidoreductases / Q000096:biosynthesis; D001665:Binding Sites; D002250:Carbon Radioisotopes; D002462:Cell Membrane / Q000378:metabolism; D004794:Enzyme Repression; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism*; D005977:Glutarates; D006720:Homozygote; D006801:Humans; D006937:Hypercholesterolemia / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D007457:Iodine Radioisotopes; D007700:Kinetics; D008077:Lipoproteins, LDL / Q000378:metabolism*; D008798:Mevalonic Acid; D011485:Protein Binding; D011955:Receptors, Drug; D012867:Skin / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D013997:Time Factors; D014461:Ultracentrifugation
D002250:Carbon Radioisotopes; D005977:Glutarates; D007457:Iodine Radioisotopes; D008077:Lipoproteins, LDL; D011955:Receptors, Drug; D000429:Alcohol Oxidoreductases; D008798:Mevalonic Acid