Carcinomatous neuromyopathy. 1. Electrophysiological studies. An electrophysiological and immunological study of patients with carcinoma of the lung.
A high incidence of asymptomatic neuromuscular disease was found. More than half showed EMG evidence of a `myopathy' and of denervation. The commonest syndrome was a neuromyopathy with myopathic units and spontaneous muscle activity, especially fasciculations and nerve fibre loss but with normal or near normal nerve conduction. This is thought to be the result of a neuronal or axonal disorder.
D000200:Action Potentials; D000230:Adenocarcinoma / Q000150:complications*; D000293:Adolescent; D000328:Adult; D000368:Aged; D018288:Carcinoma, Small Cell / Q000150:complications*; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D002349:Carpal Tunnel Syndrome / Q000503:physiopathology; D002526:Cerebellar Diseases / Q000503:physiopathology; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008475:Median Nerve / Q000503:physiopathology; D008875:Middle Aged; D009121:Muscle Denervation; D009132:Muscles / Q000503:physiopathology*; D009133:Muscular Atrophy / Q000503:physiopathology; D009157:Myasthenia Gravis / Q000209:etiology; D009431:Neural Conduction; D009443:Neuritis / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000209:etiology* / Q000503:physiopathology; D010525:Peripheral Nerves / Q000503:physiopathology*; D010543:Peroneal Nerve / Q000503:physiopathology; D012026:Reflex, Stretch; D009435:Synaptic Transmission; D013606:Tabes Dorsalis / Q000503:physiopathology; D014806:Vitamin B 12 Deficiency / Q000503:physiopathology