Synthesis of substituted piperidino carbamides: correlation between CNS effects and selective inhibition of NAD-dependent oxidations.
D000577:Amides / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology; D001921:Brain / Q000378:metabolism; D004357:Drug Synergism; D066298:In Vitro Techniques; D007656:Ketoglutaric Acids / Q000378:metabolism; D007928:Lethal Dose 50; D008297:Male; D009243:NAD / Q000037:antagonists & inhibitors*; D010084:Oxidation-Reduction; D010424:Pentobarbital / Q000494:pharmacology; D010433:Pentylenetetrazole; D010880:Piperidines / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D011773:Pyruvates / Q000378:metabolism; D051381:Rats; D012640:Seizures / Q000139:chemically induced; D012890:Sleep / Q000187:drug effects; D013386:Succinates / Q000378:metabolism; D013997:Time Factors
D000577:Amides; D000927:Anticonvulsants; D007656:Ketoglutaric Acids; D010880:Piperidines; D011773:Pyruvates; D013386:Succinates; D009243:NAD; D010424:Pentobarbital; D010433:Pentylenetetrazole