Release of infectious Epstein-Barr virus by transformed marmoset leukocytes.
Marmoset blood leukocytes transformed in vitro by Epstein-Barr virus regularly release extracellular infectious Epstein-Barr virus with high titers of transforming activity. By comparison, human umbilical cord leukocytes and adult human leukocytes transformed by Epstein-Barr virus release either no extracellular infectious virus or small amounts, irregularly.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D002725:Chloroform / Q000494:pharmacology; D003168:Complement Fixation Tests; D005019:Ethyl Ethers / Q000494:pharmacology; D005455:Fluorescent Antibody Technique; D000882:Haplorhini; D004854:Herpesvirus 4, Human / Q000187:drug effects / Q000254:growth & development* / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007244:Infectious Mononucleosis / Q000382:microbiology; D007962:Leukocytes / Q000382:microbiology*; D008854:Microscopy, Electron; D009500:Neutralization Tests; D013045:Species Specificity
D000956:Antigens, Viral; D005019:Ethyl Ethers; D002725:Chloroform