title: Characteristics of Paget's carcinoma of the nipple and problems of its negligency.
abstract: The analysis of 73 cases revealed Paget's disease of the nipple, known as a precancerous state, to be a special form of the intraductal mammary cancers. In the majority of the cases, apart from a superficial exulceration malignant transformation in the glandular substance is present. Thus, the treatment schedules have to be similar to those of other mammary cancers; in cases localized to the nipple, simple mastectomy with axillary block dissection, is suggested; in cases with tumors of the glandular substance, radical mastectomy according to Halsted is suggested. The frequent negligency is partly a result of an earlier attitude of the physicians being too conservative with therapeutic procedures.
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast; D001941:Breast Diseases / Q000175:diagnosis; D001943:Breast Neoplasms / Q000175:diagnosis; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis*; D003537:Cystadenoma / Q000175:diagnosis; D003872:Dermatitis / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D009558:Nipples; D010144:Paget's Disease, Mammary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013997:Time Factors