The inhibition of 3-alpha-hydroxy steroid-activated nicotinamide-adenine dinucleotide (phosphate) transhydrogenase by some antimetabolic compounds.
D000738:Androsterone / Q000494:pharmacology; D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology*; D002738:Chloroquine / Q000494:pharmacology; D004798:Enzymes / Q000494:pharmacology*; D004958:Estradiol / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000201:enzymology; D008297:Male; D015122:Mercaptopurine / Q000494:pharmacology*; D009249:NADP / Q000494:pharmacology; D010088:Oxidoreductases / Q000378:metabolism*; D011687:Purines / Q000494:pharmacology*; D051381:Rats; D014498:Uracil / Q000031:analogs & derivatives
D000963:Antimetabolites; D004798:Enzymes; D011687:Purines; D004958:Estradiol; D009249:NADP; D014498:Uracil; D002738:Chloroquine; D000738:Androsterone; D015122:Mercaptopurine; D010088:Oxidoreductases