Experience with pericyazine in profoundly and severely retarded children.
The effectiveness of pericyazine in severe behavioural disorders was evaluated in 15 profoundly and severely retarded children. Pericyazine provided significant improvement in such parameters as co-operation, temper, purposeless activities, hyperactivity, communication and mood. It proved to be statistically superior to the minor tranquillizers in improving co-operation and helpfulness, temper, mood, the understanding of commands and table manners, and in reducing self-abusiveness and abusiveness to staff. The safety of this agent was confirmed and photosensitivity was not found to be associated with its use.
D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy*; D008297:Male; D009570:Nitriles / Q000627:therapeutic use*; D010640:Phenothiazines / Q000627:therapeutic use*; D010880:Piperidines / Q000627:therapeutic use*; D010919:Placebos; D011581:Psychological Tests; D013997:Time Factors; D014149:Tranquilizing Agents / Q000627:therapeutic use*
D009570:Nitriles; D010640:Phenothiazines; D010880:Piperidines; D010919:Placebos; D014149:Tranquilizing Agents