The antagonism of the local anaesthetic activity and of acute toxicity of propranolol and pronethalol by  -adrenergic blocking agents.
D000317:Adrenergic alpha-Antagonists / Q000037:antagonists & inhibitors / Q000494:pharmacology; D000779:Anesthetics, Local / Q000037:antagonists & inhibitors*; D000818:Animals; D003315:Cornea / Q000187:drug effects; D004338:Drug Combinations; D004983:Ethanolamines / Q000037:antagonists & inhibitors* / Q000633:toxicity; D005260:Female; D006168:Guinea Pigs; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D010643:Phenoxybenzamine / Q000494:pharmacology; D011343:Procaine / Q000494:pharmacology; D011433:Propranolol / Q000037:antagonists & inhibitors* / Q000633:toxicity; D011817:Rabbits; D013565:Sympatholytics / Q000494:pharmacology*; D013997:Time Factors; D014043:Tolazoline / Q000494:pharmacology
D000317:Adrenergic alpha-Antagonists; D000779:Anesthetics, Local; D004338:Drug Combinations; D004983:Ethanolamines; D013565:Sympatholytics; D010643:Phenoxybenzamine; D011343:Procaine; D011433:Propranolol; D014043:Tolazoline