title: Interactions of spironolactone with hepatic microsomal drug-metabolizing enzyme systems.
mesh_terms: D000818:Animals; D003580:Cytochromes / Q000378:metabolism*; D003640:Dealkylation; D004336:Drug Antagonism; D004579:Electron Transport / Q000187:drug effects; D004790:Enzyme Induction; D006591:Hexobarbital / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology* / Q000378:metabolism; D009019:Morphinans / Q000037:antagonists & inhibitors / Q000378:metabolism; D009249:NADP; D010088:Oxidoreductases / Q000378:metabolism*; D012890:Sleep / Q000187:drug effects; D013148:Spironolactone / Q000494:pharmacology*
chemical_list: D003580:Cytochromes; D009019:Morphinans; D013148:Spironolactone; D009249:NADP; D006591:Hexobarbital; D010088:Oxidoreductases