3-Hydroxylation of coumarin or 4-methylcoumarin by rat-liver microsomes and its induction by 4-methylcoumarin given orally.
D000818:Animals; D003374:Coumarins / Q000008:administration & dosage / Q000378:metabolism* / Q000494:pharmacology; D003609:Dactinomycin / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D006863:Hydrogen-Ion Concentration; D006900:Hydroxylation; D007700:Kinetics; D008297:Male; D008745:Methylation; D008862:Microsomes, Liver / Q000032:analysis / Q000201:enzymology* / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000378:metabolism*; D009243:NAD / Q000494:pharmacology; D009249:NADP / Q000494:pharmacology; D010740:Phospholipases / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011506:Proteins / Q000032:analysis; D051381:Rats; D013501:Surface-Active Agents / Q000494:pharmacology
D003374:Coumarins; D011506:Proteins; D013501:Surface-Active Agents; D009243:NAD; D003609:Dactinomycin; D009249:NADP; D011335:Proadifen; D006899:Mixed Function Oxygenases; D010740:Phospholipases