Abnormal autolytic enzyme in a pneumococus with altered teichoic acid composition.
Pneumococci in which the choline component of the cell wall teichoic acid was replaced by ethanolamine contain an abnormal autolytic enzyme that has a low molecular weight and low activity in contrast to the enzyme typical of choline-containing bacteria that has a high molecular weight and high activity. The abnormal autolysin can be converted to the normal (cholinetype) enzyme by incubation in vitro with choline-containing cell walls.
D000605:Amino Alcohols; D001329:Autolysis; D001673:Biodegradation, Environmental; D002247:Carbon Isotopes; D002473:Cell Wall / Q000032:analysis / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D002794:Choline; D003470:Culture Media; D006027:Glycosides / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D009113:Muramidase / Q000378:metabolism; D010756:Phosphoric Acids / Q000378:metabolism*; D013296:Streptococcus pneumoniae / Q000201:enzymology* / Q000378:metabolism; D013682:Teichoic Acids / Q000032:analysis / Q000378:metabolism; D014316:Tritium
D000605:Amino Alcohols; D002247:Carbon Isotopes; D003470:Culture Media; D006027:Glycosides; D010756:Phosphoric Acids; D013682:Teichoic Acids; D014316:Tritium; D009113:Muramidase; D002794:Choline