title: A thermodynamic approach to problems of drug antagonism I. The "Charnière theory".
mesh_terms: D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D001285:Atropine / Q000032:analysis / Q000037:antagonists & inhibitors; D001665:Binding Sites; D055598:Chemical Phenomena; D002621:Chemistry; D004155:Diphenhydramine / Q000494:pharmacology; D004336:Drug Antagonism; D004735:Energy Transfer; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D006634:Histamine H1 Antagonists; D007082:Ileum / Q000378:metabolism; D008962:Models, Theoretical; D004856:Postural Balance; D011955:Receptors, Drug; D013816:Thermodynamics
chemical_list: D006634:Histamine H1 Antagonists; D011955:Receptors, Drug; D001285:Atropine; D006632:Histamine; D004155:Diphenhydramine; D000109:Acetylcholine