Liver microsomal metabolism of aflatoxin B 1  to a reactive derivative toxic to Salmonella typhimurium TA 1530.
D000348:Aflatoxins / Q000302:isolation & purification / Q000378:metabolism* / Q000633:toxicity; D000814:Aniline Compounds / Q000494:pharmacology; D000818:Animals; D002273:Carcinogens / Q000378:metabolism / Q000494:pharmacology / Q000633:toxicity; D002845:Chromatography; D006224:Cricetinae; D004247:DNA / Q000494:pharmacology; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D007016:Hypophysectomy; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008862:Microsomes, Liver / Q000032:analysis / Q000187:drug effects / Q000378:metabolism*; D009183:Mycotoxins / Q000494:pharmacology; D009249:NADP / Q000494:pharmacology; D010634:Phenobarbital / Q000494:pharmacology; D010902:Pituitary Gland / Q000502:physiology; D012313:RNA / Q000032:analysis / Q000494:pharmacology; D051381:Rats; D012486:Salmonella typhimurium / Q000187:drug effects*; D012737:Sex Factors; D013045:Species Specificity; D014966:Xanthenes / Q000494:pharmacology
D000348:Aflatoxins; D000814:Aniline Compounds; D002273:Carcinogens; D009183:Mycotoxins; D014966:Xanthenes; D009249:NADP; D012313:RNA; D004247:DNA; D010634:Phenobarbital