N-oxide formation: a new route for inactivation of the antihistaminic chlorcyclizine.
D000818:Animals; D002845:Chromatography; D003377:Countercurrent Distribution; D005260:Female; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D006634:Histamine H1 Antagonists / Q000378:metabolism* / Q000494:pharmacology; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D008099:Liver / Q000166:cytology; D008861:Microsomes / Q000378:metabolism; D009609:Nitrous Oxide / Q000652:urine*; D010879:Piperazines / Q000378:metabolism; D051381:Rats; D013057:Spectrum Analysis; D014466:Ultraviolet Rays
D006634:Histamine H1 Antagonists; D010879:Piperazines; D006632:Histamine; D009609:Nitrous Oxide