Some observations on the estimation of 3-methoxytyramine in brain tissue.
1. A new method for the estimation of 4-hydroxy-3-methoxyphenylethylamine (3-methoxytyramine) in brain tissue is described. This is based on the formation of a fluorescent derivative by oxidation with potassium ferricyanide in ammonium hydroxide solution.2. The effects of some drugs on the concentration of 3-methoxytyramine in the brain are reported.3. The significance of changes in the striatal concentration of 3-methoxytyramine is discussed.
D000661:Amphetamine / Q000494:pharmacology; D000818:Animals; D001479:Basal Ganglia / Q000032:analysis; D001923:Brain Chemistry; D002421:Caudate Nucleus / Q000032:analysis; D002623:Chemistry Techniques, Analytical; D002746:Chlorpromazine / Q000494:pharmacology; D003042:Cocaine / Q000494:pharmacology; D004285:Dogs; D004298:Dopamine / Q000032:analysis; D005470:Fluorometry; D006168:Guinea Pigs; D006834:Hydrazines / Q000494:pharmacology; D051379:Mice; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D010627:Phenethylamines / Q000032:analysis*; D011817:Rabbits; D051381:Rats; D013565:Sympatholytics / Q000032:analysis*
D006834:Hydrazines; D008996:Monoamine Oxidase Inhibitors; D010627:Phenethylamines; D013565:Sympatholytics; D000661:Amphetamine; D003042:Cocaine; D002746:Chlorpromazine; D004298:Dopamine