Investigation of the component reactions of oxidative sterol demethylation. Oxidation of a 4 alpha-methyl sterol to a 4 alpha-carboxylic acid during cholesterol biosynthesis.
D000096:Acetone; D000143:Acids / Q000096:biosynthesis; D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism; D002247:Carbon Isotopes; D002784:Cholesterol / Q000096:biosynthesis*; D002855:Chromatography, Thin Layer; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D009243:NAD; D009249:NADP; D010084:Oxidation-Reduction; D010100:Oxygen; D051381:Rats; D013057:Spectrum Analysis; D013261:Sterols / Q000302:isolation & purification / Q000378:metabolism*; D014316:Tritium
D000143:Acids; D002247:Carbon Isotopes; D013261:Sterols; D009243:NAD; D014316:Tritium; D000096:Acetone; D002245:Carbon Dioxide; D009249:NADP; D002784:Cholesterol; D010100:Oxygen