title: Kinetic studies of the reaction mechanism of dihydrofolate reductase.
mesh_terms: D001665:Binding Sites; D013293:Enterococcus faecalis / Q000201:enzymology; D005493:Folic Acid Antagonists; D007700:Kinetics; D009154:Mutation; D009249:NADP; D009994:Osmolar Concentration; D011485:Protein Binding; D011725:Pyridines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology; D013238:Stereotaxic Techniques; D013329:Structure-Activity Relationship; D013762:Tetrahydrofolate Dehydrogenase; D014227:Triazines / Q000494:pharmacology
chemical_list: D005493:Folic Acid Antagonists; D011725:Pyridines; D011743:Pyrimidines; D014227:Triazines; D009249:NADP; D013762:Tetrahydrofolate Dehydrogenase