Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. 3. Properties of the reconstituted 3,4-benzypyrene hydroxylase system.
D000645:Ammonium Sulfate; D000818:Animals; D001580:Benzopyrenes; D001647:Bile Acids and Salts; D002384:Catalysis; D011232:Chemical Precipitation; D003577:Cytochrome P-450 Enzyme System; D003574:Cytochrome c Group; D003580:Cytochromes; D004789:Enzyme Activation; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008055:Lipids; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000201:enzymology*; D006899:Mixed Function Oxygenases; D009243:NAD; D009249:NADP; D010088:Oxidoreductases / Q000302:isolation & purification; D010634:Phenobarbital / Q000494:pharmacology; D010713:Phosphatidylcholines; D051381:Rats; D013501:Surface-Active Agents
D001580:Benzopyrenes; D001647:Bile Acids and Salts; D003574:Cytochrome c Group; D003580:Cytochromes; D008055:Lipids; D010713:Phosphatidylcholines; D013501:Surface-Active Agents; D009243:NAD; D009249:NADP; D008748:Methylcholanthrene; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D000645:Ammonium Sulfate; D010634:Phenobarbital