title: Induction of N-acetylglucosamine kinase in yeast.
abstract: The presence of N-acetylglucosamine is essential for the induced synthesis of N-acetylglucosamine kinase in Candida albicans. The enzyme synthesis stops and its concentration in the cells declines rapidly as soon as N-acetylglucosamine is removed from the medium. Experiments with RNA- and protein-synthesis inhibitors indicate that the appearance of new enzyme activity is dependent on concomitant new protein synthesis and the inducer operates at a transcriptional level.
mesh_terms: D002176:Candida albicans / Q000201:enzymology*; D003513:Cycloheximide; D003609:Dactinomycin; D004790:Enzyme Induction; D005656:Fungal Proteins / Q000096:biosynthesis; D005944:Glucosamine / Q000031:analogs & derivatives; D006918:Hydroxyurea; D008937:Mitomycins; D010770:Phosphotransferases / Q000096:biosynthesis*; D012313:RNA / Q000096:biosynthesis; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014529:Uridine / Q000378:metabolism
chemical_list: D005656:Fungal Proteins; D008937:Mitomycins; D003609:Dactinomycin; D012313:RNA; D003513:Cycloheximide; D010770:Phosphotransferases; D005944:Glucosamine; D013936:Thymidine; D014529:Uridine; D006918:Hydroxyurea