Folate reductase of the amethopterin-resistant Streptococcus faecium var. durans-Ak. I. Inhibition by amethopterin and methasquin, a new quinazoline antifolate.
D001224:Aspartic Acid / Q000494:pharmacology*; D002848:Chromatography, DEAE-Cellulose; D004586:Electrophoresis; D005493:Folic Acid Antagonists; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008727:Methotrexate / Q000494:pharmacology*; D008970:Molecular Weight; D009249:NADP / Q000494:pharmacology; D011189:Potassium Chloride; D011799:Quinazolines / Q000494:pharmacology*; D013291:Streptococcus / Q000187:drug effects / Q000201:enzymology*; D013762:Tetrahydrofolate Dehydrogenase / Q000302:isolation & purification
D005493:Folic Acid Antagonists; D011799:Quinazolines; D001224:Aspartic Acid; D009249:NADP; D011189:Potassium Chloride; D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate