The role of heme synthesis during the induction of hepatic microsomal cytochrome P-450 and drug metabolism produced by benzpyrene.
D000217:Acyltransferases / Q000096:biosynthesis* / Q000378:metabolism; D000596:Amino Acids; D000818:Animals; D001391:Azo Compounds / Q000378:metabolism; D001580:Benzopyrenes / Q000494:pharmacology*; D002247:Carbon Isotopes; D003580:Cytochromes / Q000096:biosynthesis*; D003864:Depression, Chemical; D004790:Enzyme Induction; D005998:Glycine / Q000378:metabolism; D006418:Heme / Q000096:biosynthesis*; D007982:Levulinic Acids; D008099:Liver / Q000378:metabolism*; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D009249:NADP; D010088:Oxidoreductases / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D013268:Stimulation, Chemical; D013997:Time Factors; D014166:Transferases / Q000096:biosynthesis; D014230:Triazoles / Q000494:pharmacology
D000596:Amino Acids; D001391:Azo Compounds; D001580:Benzopyrenes; D002247:Carbon Isotopes; D003580:Cytochromes; D007982:Levulinic Acids; D014230:Triazoles; D006418:Heme; D009249:NADP; D010088:Oxidoreductases; D014166:Transferases; D000217:Acyltransferases; D005998:Glycine; D010634:Phenobarbital