title: Studies on a new 1,5-benzothiazepine derivative (CRD-401). 3. Effects of optical isomers of CRD-401 on smooth muscle and other pharmacological properties.
mesh_terms: D000779:Anesthetics, Local; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000927:Anticonvulsants / Q000494:pharmacology; D001464:Barium / Q000037:antagonists & inhibitors; D001552:Benzazepines / Q000494:pharmacology* / Q000633:toxicity; D001777:Blood Coagulation / Q000187:drug effects; D002415:Cats; D003106:Colon / Q000187:drug effects; D003864:Depression, Chemical; D004569:Electroencephalography; D005730:Ganglionic Blockers / Q000494:pharmacology; D005769:Gastrointestinal Motility / Q000187:drug effects; D006168:Guinea Pigs; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D007536:Isomerism; D007928:Lethal Dose 50; D008297:Male; D008688:Methacholine Compounds / Q000037:antagonists & inhibitors; D051379:Mice; D009130:Muscle, Smooth / Q000187:drug effects*; D009538:Nicotine / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D012890:Sleep / Q000187:drug effects; D014649:Vas Deferens / Q000187:drug effects
chemical_list: D000779:Anesthetics, Local; D000893:Anti-Inflammatory Agents; D000927:Anticonvulsants; D001552:Benzazepines; D005730:Ganglionic Blockers; D006634:Histamine H1 Antagonists; D008688:Methacholine Compounds; D001464:Barium; D009538:Nicotine