Combined effects of diphenyliodonium chloride, pine oils, and mustard oil soaps on certain microorganisms.
Bactericidal and bacteriostatic activities of an emulsion containing 10.0% (v/v) terpineol, 0.5% (w/v) diphenyliodonium chloride, 11.0% (v/v) ethyl alcohol, and 5.62% saponified mustard oil were tested against a number of different types of organisms. The bactericidal concentration for Salmonella typhosa was 1:400. In the presence of 5.0% horse serum, it increased to 1:250. The bacteriostatic concentration varied from organism to organism; Escherichia coli and Staphylococcus aureus required 4,000 mug/ml for complete bacteriostasis, whereas Corynebacterium diphtheriae, Salmonella paratyphi-A, and Shigella required only 2,000 mug/ml for complete inhibition. A 4.0% concentration of the emulsion killed the spores of Bacillus subtilis within 6 hr.
D001431:Bacteriological Techniques; D003353:Corynebacterium diphtheriae / Q000187:drug effects; D004202:Disinfectants / Q000494:pharmacology*; D004655:Emulsions; D004926:Escherichia coli / Q000187:drug effects; D000431:Ethanol / Q000494:pharmacology; D007455:Iodine / Q000494:pharmacology*; D009150:Mustard Compounds / Q000494:pharmacology*; D010636:Phenols / Q000494:pharmacology; D012482:Salmonella paratyphi A / Q000187:drug effects; D012485:Salmonella typhi / Q000187:drug effects; D012762:Shigella dysenteriae / Q000187:drug effects; D012764:Shigella sonnei / Q000187:drug effects; D012915:Soaps; D013170:Spores / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects; D013296:Streptococcus pneumoniae / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects; D013729:Terpenes / Q000494:pharmacology*
D004202:Disinfectants; D004655:Emulsions; D009150:Mustard Compounds; D010636:Phenols; D012915:Soaps; D013729:Terpenes; D000431:Ethanol; D007455:Iodine