title: On the mechanism of carbon tetrachloride toxicity--coincidence of loss of drug-metabolizing activity with peroxidation of microsomal lipid.
mesh_terms: D000633:Aminopyrine N-Demethylase / Q000032:analysis; D000818:Animals; D001205:Ascorbic Acid / Q000494:pharmacology; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism*; D003579:Cytochrome Reductases / Q000032:analysis; D066298:In Vitro Techniques; D050356:Lipid Metabolism; D008297:Male; D008314:Malonates / Q000096:biosynthesis; D008862:Microsomes, Liver / Q000032:analysis / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D009249:NADP; D010084:Oxidation-Reduction; D010545:Peroxides / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011506:Proteins / Q000032:analysis; D051381:Rats
chemical_list: D008314:Malonates; D010545:Peroxides; D004364:Pharmaceutical Preparations; D011506:Proteins; D009249:NADP; D000633:Aminopyrine N-Demethylase; D003579:Cytochrome Reductases; D001205:Ascorbic Acid