Negative chronotropic response to phenylephrine of the canine S-A node.
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects*; D003864:Depression, Chemical; D004285:Dogs; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006584:Hexamethonium Compounds / Q000494:pharmacology; D008297:Male; D010643:Phenoxybenzamine / Q000494:pharmacology; D010656:Phenylephrine / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D011433:Propranolol / Q000494:pharmacology; D012849:Sinoatrial Node / Q000187:drug effects*; D013268:Stimulation, Chemical; D013757:Tetraethylammonium Compounds / Q000494:pharmacology; D013779:Tetrodotoxin / Q000494:pharmacology
D000317:Adrenergic alpha-Antagonists; D006584:Hexamethonium Compounds; D013757:Tetraethylammonium Compounds; D010643:Phenoxybenzamine; D010656:Phenylephrine; D013779:Tetrodotoxin; D001285:Atropine; D011433:Propranolol