Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. II. Role of the cytochrome P-450 and P-448 fractions in drug and steroid hydroxylations.
D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism; D002247:Carbon Isotopes; D002384:Catalysis; D003580:Cytochromes / Q000494:pharmacology*; D003640:Dealkylation; D004790:Enzyme Induction; D006900:Hydroxylation; D050356:Lipid Metabolism; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D009249:NADP; D010088:Oxidoreductases / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D010879:Piperazines / Q000378:metabolism; D051381:Rats; D013739:Testosterone / Q000378:metabolism
D001580:Benzopyrenes; D002247:Carbon Isotopes; D003580:Cytochromes; D010879:Piperazines; D013739:Testosterone; D009249:NADP; D008748:Methylcholanthrene; D010088:Oxidoreductases; D010634:Phenobarbital