Structural requirement for antitussive activity in some novel 16-substituted derivatives of 6,14-endoethenotetrahydrothebaine.
D000698:Analgesia; D000818:Animals; D000996:Antitussive Agents / Q000627:therapeutic use*; D002415:Cats; D003061:Codeine / Q000627:therapeutic use; D003371:Cough / Q000188:drug therapy*; D006168:Guinea Pigs; D008691:Methadone / Q000627:therapeutic use; D009019:Morphinans / Q000008:administration & dosage / Q000138:chemical synthesis / Q000627:therapeutic use*; D009020:Morphine / Q000627:therapeutic use; D051381:Rats
D000996:Antitussive Agents; D009019:Morphinans; D009020:Morphine; D008691:Methadone; D003061:Codeine