Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450.
D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D003580:Cytochromes; D006418:Heme; D008027:Light; D008297:Male; D013058:Mass Spectrometry; D008861:Microsomes / Q000187:drug effects / Q000201:enzymology*; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D009249:NADP; D010088:Oxidoreductases / Q000528:radiation effects; D010100:Oxygen; D010103:Oxygen Isotopes; D010105:Oxygenases / Q000037:antagonists & inhibitors / Q000528:radiation effects; D010777:Photochemistry / Q000295:instrumentation; D011830:Radiation Effects; D051381:Rats; D013154:Spleen / Q000166:cytology / Q000187:drug effects / Q000201:enzymology*; D014867:Water
D003580:Cytochromes; D010103:Oxygen Isotopes; D014867:Water; D006418:Heme; D009249:NADP; D002248:Carbon Monoxide; D010088:Oxidoreductases; D010105:Oxygenases; D010100:Oxygen