Temperature in the monkey: transmitter factors released from the brain during thermoregulation.
When perfusate is collected from the anterior hypothalamus of a cooled donor monkey and is transfused to a corresponding hypothalamic site in a normal monkey, fever occurs in this recipient. Conversely, perfusate from a heated donor monkey lowers the recipient monkey's temperature when the same hypothalamic transfusion procedure is followed. These experiments provide direct evidence of a neurochemical "coding" within the specific anatomical region of the brain historically implicated in the control of body temperature.
D000818:Animals; D001833:Body Temperature Regulation; D002555:Cerebrospinal Fluid; D005334:Fever / Q000139:chemically induced; D000882:Haplorhini; D007031:Hypothalamus / Q000502:physiology*; D008297:Male; D018377:Neurotransmitter Agents / Q000502:physiology*; D010477:Perfusion; D013238:Stereotaxic Techniques
D018377:Neurotransmitter Agents