title: -adrenergic blocking agents. 3-(3-Substituted-amino-2-hydroxypropoxy)-4-substituted-1,2,5-thiadiazoles.
mesh_terms: D000433:1-Propanol / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity; D000319:Adrenergic beta-Antagonists / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity; D000605:Amino Alcohols / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D004347:Drug Interactions; D006339:Heart Rate / Q000187:drug effects; D006571:Heterocyclic Compounds / Q000138:chemical synthesis*; D007545:Isoproterenol / Q000494:pharmacology; D007928:Lethal Dose 50; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013329:Structure-Activity Relationship; D013565:Sympatholytics / Q000138:chemical synthesis*; D013830:Thiadiazoles / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity
chemical_list: D000319:Adrenergic beta-Antagonists; D000605:Amino Alcohols; D006571:Heterocyclic Compounds; D013565:Sympatholytics; D013830:Thiadiazoles; D000433:1-Propanol; D007545:Isoproterenol