An effect of ethanol administration on tryptophan oxygenase in the perfused rat liver. Decreased enzyme synthesis dependent on low perfusate pH.
D000085:Acetates / Q000032:analysis; D000818:Animals; D001646:Bile / Q000201:enzymology; D003513:Cycloheximide / Q000494:pharmacology; D000431:Ethanol / Q000032:analysis / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology; D006851:Hydrochloric Acid; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007737:Kynurenine / Q000096:biosynthesis; D007773:Lactates / Q000032:analysis; D008099:Liver / Q000187:drug effects / Q000201:enzymology* / Q000378:metabolism; D008297:Male; D009243:NAD / Q000032:analysis; D010477:Perfusion; D011720:Pyrazoles / Q000032:analysis; D051381:Rats; D013997:Time Factors; D014366:Tryptophan Oxygenase / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D014444:Tyrosine Transaminase / Q000032:analysis
D000085:Acetates; D007773:Lactates; D011720:Pyrazoles; D009243:NAD; D007737:Kynurenine; D000431:Ethanol; D003513:Cycloheximide; D014366:Tryptophan Oxygenase; D014444:Tyrosine Transaminase; D005947:Glucose; D006851:Hydrochloric Acid