Evidence that the hypotensive action of methyldopa is mediated by central actions of methylnoradrenaline.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D001921:Brain / Q000187:drug effects*; D001923:Brain Chemistry / Q000187:drug effects; D004298:Dopamine / Q000032:analysis; D008750:Methyldopa / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000494:pharmacology*; D008781:Methyltyrosines / Q000494:pharmacology; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors; D009638:Norepinephrine / Q000032:analysis; D009647:Normetanephrine / Q000096:biosynthesis / Q000494:pharmacology*; D011422:Propionates / Q000494:pharmacology; D051381:Rats; D013859:Thiocarbamates / Q000494:pharmacology
D008781:Methyltyrosines; D011422:Propionates; D013859:Thiocarbamates; D009647:Normetanephrine; D008750:Methyldopa; D006899:Mixed Function Oxygenases; D004298:Dopamine; D009638:Norepinephrine