title: Irreversible adrenergic  -receptor antagonism by (R)-and (S)-N-(2-chloroethyl)-N-methyl-2-phenyl-2-hydroxyethylamine and related agents.
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D002713:Chlorine; D004983:Ethanolamines / Q000138:chemical synthesis* / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008968:Molecular Conformation; D009119:Muscle Contraction / Q000187:drug effects; D010627:Phenethylamines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013997:Time Factors; D014649:Vas Deferens / Q000187:drug effects
chemical_list: D000317:Adrenergic alpha-Antagonists; D004983:Ethanolamines; D010627:Phenethylamines; D011941:Receptors, Adrenergic; D002713:Chlorine