Administration of two or more related drugs to investigate the effect of molecular modification and formulation on drug absorption, metabolism and excretion.
D000328:Adult; D000661:Amphetamine / Q000378:metabolism* / Q000652:urine; D002745:Chlorphentermine / Q000378:metabolism; D002849:Chromatography, Gas; D005277:Fenfluramine / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007408:Intestinal Absorption; D008297:Male; D008875:Middle Aged; D010645:Phentermine / Q000378:metabolism; D013329:Structure-Activity Relationship; D013997:Time Factors; D014556:Urine / Q000502:physiology
D005277:Fenfluramine; D010645:Phentermine; D000661:Amphetamine; D002745:Chlorphentermine