A study of some possible mechanisms by which glucose inhibits drug metabolism in vivo and in vitro.
D000818:Animals; D001463:Barbiturates / Q000378:metabolism*; D001589:Benzphetamine / Q000494:pharmacology; D001923:Brain Chemistry; D002247:Carbon Isotopes; D003576:Electron Transport Complex IV / Q000032:analysis / Q000037:antagonists & inhibitors; D005947:Glucose / Q000494:pharmacology*; D005954:Glucosephosphate Dehydrogenase / Q000032:analysis; D006591:Hexobarbital / Q000378:metabolism; D007700:Kinetics; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008862:Microsomes, Liver / Q000378:metabolism; D009249:NADP; D009929:Organ Size; D010088:Oxidoreductases / Q000032:analysis; D010424:Pentobarbital / Q000032:analysis / Q000097:blood / Q000378:metabolism / Q000494:pharmacology; D012890:Sleep / Q000187:drug effects
D001463:Barbiturates; D002247:Carbon Isotopes; D001589:Benzphetamine; D009249:NADP; D006591:Hexobarbital; D010088:Oxidoreductases; D005954:Glucosephosphate Dehydrogenase; D003576:Electron Transport Complex IV; D010424:Pentobarbital; D005947:Glucose