The effect of alkyl substitution in drugs. XXI. Synthesis and a comparative pharmacological study of a number of potential orphenadrine metabolites.
D000818:Animals; D001464:Barium / Q000037:antagonists & inhibitors; D002712:Chlorides / Q000037:antagonists & inhibitors; D006168:Guinea Pigs; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D007082:Ileum / Q000187:drug effects; D066298:In Vitro Techniques; D007422:Intestines / Q000187:drug effects; D007583:Jejunum / Q000187:drug effects; D051379:Mice; D009184:Mydriatics / Q000494:pharmacology; D009966:Orphenadrine / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology* / Q000633:toxicity; D010276:Parasympatholytics / Q000494:pharmacology; D010277:Parasympathomimetics / Q000037:antagonists & inhibitors; D011759:Pyrrolidines / Q000037:antagonists & inhibitors; D051381:Rats; D013747:Tetrabenazine / Q000037:antagonists & inhibitors; D014203:Tremorine / Q000037:antagonists & inhibitors
D002712:Chlorides; D006634:Histamine H1 Antagonists; D009184:Mydriatics; D010276:Parasympatholytics; D010277:Parasympathomimetics; D011759:Pyrrolidines; D001464:Barium; D009966:Orphenadrine; D014203:Tremorine; D013747:Tetrabenazine