[Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].
D000438:Alcohols; D000818:Animals; D002248:Carbon Monoxide / Q000494:pharmacology; D002251:Carbon Tetrachloride / Q000378:metabolism*; D002725:Chloroform / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003891:Desipramine / Q000494:pharmacology; D004221:Disulfiram / Q000494:pharmacology; D005419:Flavonoids / Q000494:pharmacology; D008041:Linoleic Acids / Q000494:pharmacology; D050356:Lipid Metabolism; D008297:Male; D008797:Metyrapone / Q000494:pharmacology; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D009249:NADP; D010084:Oxidation-Reduction; D010100:Oxygen / Q000494:pharmacology; D010105:Oxygenases / Q000494:pharmacology; D010882:Piperonyl Butoxide / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D014466:Ultraviolet Rays
D000438:Alcohols; D005419:Flavonoids; D008041:Linoleic Acids; D009249:NADP; D002248:Carbon Monoxide; D002725:Chloroform; D003577:Cytochrome P-450 Enzyme System; D002251:Carbon Tetrachloride; D010105:Oxygenases; D010882:Piperonyl Butoxide; D010100:Oxygen; D003891:Desipramine; D004221:Disulfiram; D008797:Metyrapone
Bildung von Chloroform aus Tetrachlorkohlenstoff in Lebermikrosomen, Lipidperoxidation und Zerstörung von Cytochrom P-450.