Possible mechanism (s) of alprenolol (beta adrenergic receptor blocking agent) prolongation of pentobarbital hypnosis in mice.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000526:Alprenolol / Q000008:administration & dosage / Q000494:pharmacology; D000605:Amino Alcohols / Q000494:pharmacology*; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001923:Brain Chemistry / Q000187:drug effects; D002247:Carbon Isotopes; D004357:Drug Synergism; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D009043:Motor Activity / Q000187:drug effects; D010424:Pentobarbital / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism / Q000494:pharmacology*; D012890:Sleep / Q000187:drug effects*; D013565:Sympatholytics / Q000494:pharmacology*; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D000605:Amino Alcohols; D002247:Carbon Isotopes; D013565:Sympatholytics; D000526:Alprenolol; D010424:Pentobarbital