Double peaked positive chronotropic response of the isolated blood-perfused S-A node to caffeine.
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D001769:Blood; D002110:Caffeine / Q000494:pharmacology*; D003864:Depression, Chemical; D004285:Dogs; D006339:Heart Rate / Q000187:drug effects*; D066298:In Vitro Techniques; D010477:Perfusion; D011433:Propranolol / Q000494:pharmacology; D012849:Sinoatrial Node / Q000187:drug effects*; D013268:Stimulation, Chemical; D013779:Tetrodotoxin / Q000494:pharmacology
D000319:Adrenergic beta-Antagonists; D002110:Caffeine; D013779:Tetrodotoxin; D011433:Propranolol