Inhibition of the immune response to pertussis vaccine during Plasmodium berghei yoelii infection in mice.
Mice infected with Plasmodium berghei yoelii responded poorly to pertussis vaccine when administered at peak parasitemia. This was shown by serum agglutinin titers and lack of protection against intracerebral challenge with virulent Bordetella pertussis.
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D000917:Antibody Formation; D001885:Bordetella Infections / Q000517:prevention & control; D001886:Bordetella pertussis / Q000276:immunology; D007165:Immunosuppression Therapy; D008288:Malaria / Q000209:etiology / Q000276:immunology*; D008297:Male; D051379:Mice; D010567:Pertussis Vaccine; D010962:Plasmodium berghei; D014611:Vaccination
D000907:Antibodies, Bacterial; D010567:Pertussis Vaccine