title: Increased dihydrofolate reductase synthesis in Diplococcus pneumoniae following translatable alteration of the structural gene. 3. Further evidence on the extent of genic involvement.
mesh_terms: D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004355:Drug Stability; D005796:Genes; D008727:Methotrexate; D009154:Mutation; D009876:Operon; D011485:Protein Binding; D011995:Recombination, Genetic; D013296:Streptococcus pneumoniae / Q000201:enzymology*; D013696:Temperature; D013762:Tetrahydrofolate Dehydrogenase / Q000096:biosynthesis*; D014170:Transformation, Genetic
chemical_list: D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate