An inhibitor of phospholipase D in saliva.
1. Bovine, dog and human saliva contain substances which inhibit the soluble phospholipase D present in grass leaf or celery stalk. 2. The inhibitor in bovine saliva is of high molecular weight and exhibits considerable stability to heat, acids and alkalis. 3. The inhibitor has been purified free from salivary mucoprotein. 4. It is suggested that the inhibitor could protect the upper alimentary tract of a herbage-eating animal from the necrotic action of phospholipase D.
D000818:Animals; D002417:Cattle; D003016:Clostridium perfringens / Q000201:enzymology; D004285:Dogs; D006358:Hot Temperature; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008970:Molecular Weight; D009088:Mucoproteins / Q000032:analysis; D010740:Phospholipases / Q000037:antagonists & inhibitors*; D006109:Poaceae / Q000201:enzymology; D012463:Saliva / Q000032:analysis*; D012910:Snake Venoms / Q000037:antagonists & inhibitors
D009088:Mucoproteins; D012910:Snake Venoms; D010740:Phospholipases