Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.
D000632:Aminopyrine / Q000378:metabolism; D000818:Animals; D001067:Appetite Depressants / Q000378:metabolism*; D001589:Benzphetamine / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000494:pharmacology; D003580:Cytochromes / Q000378:metabolism*; D003864:Depression, Chemical; D004987:Ethers / Q000378:metabolism; D005227:Fatty Acids / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000494:pharmacology; D005557:Formaldehyde / Q000096:biosynthesis; D006591:Hexobarbital / Q000378:metabolism; D050356:Lipid Metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008861:Microsomes / Q000201:enzymology / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009019:Morphinans / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D010088:Oxidoreductases / Q000494:pharmacology; D010627:Phenethylamines / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D011437:Propylamines / Q000378:metabolism*; D011817:Rabbits; D013053:Spectrophotometry
D001067:Appetite Depressants; D003580:Cytochromes; D004987:Ethers; D005227:Fatty Acids; D009019:Morphinans; D010627:Phenethylamines; D011437:Propylamines; D000632:Aminopyrine; D001589:Benzphetamine; D005557:Formaldehyde; D009249:NADP; D006591:Hexobarbital; D006899:Mixed Function Oxygenases; D010088:Oxidoreductases; D010634:Phenobarbital