Importance of demethylenation in the metabolism in vivo and in vitro of methylenedioxyphenyl synergists and related compounds in mammals.
D000284:Administration, Oral; D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism; D002247:Carbon Isotopes; D002254:Carbonates / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D002855:Chromatography, Thin Layer; D006224:Cricetinae; D004149:Dioxoles / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism* / Q000652:urine; D004357:Drug Synergism; D005243:Feces / Q000032:analysis; D005557:Formaldehyde / Q000494:pharmacology; D066298:In Vitro Techniques; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D009249:NADP / Q000378:metabolism; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D012964:Sodium / Q000494:pharmacology; D013045:Species Specificity; D013454:Sulfoxides / Q000652:urine
D002247:Carbon Isotopes; D002254:Carbonates; D004149:Dioxoles; D013454:Sulfoxides; D002245:Carbon Dioxide; D005557:Formaldehyde; D009249:NADP; D012964:Sodium; D010088:Oxidoreductases