Synthesis of some isoindolines and 1,2,3,4-tetrahydroisoquinolines and their evaluation as alpha-adrenergic and adrenergic neuron blocking agents.
D000317:Adrenergic alpha-Antagonists / Q000138:chemical synthesis / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D002415:Cats; D005069:Evaluation Studies as Topic; D006321:Heart / Q000187:drug effects; D007082:Ileum / Q000187:drug effects; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D007546:Isoquinolines / Q000138:chemical synthesis; D051379:Mice; D009541:Nictitating Membrane / Q000187:drug effects; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship; D013565:Sympatholytics / Q000138:chemical synthesis*
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D007211:Indoles; D007546:Isoquinolines; D011804:Quinolines; D013565:Sympatholytics