Chemistry and pharmacology of a new potential antidepressant. (N-methyl-N-[4-chlorobenzyl-methyl-3-(10,11-dihydro-5H-dibenz(b,f) azepin-5-yl)]-propylamine hydrochloride). (Leo 640, lopraminehydrochloride).
D000042:Absorption; D000818:Animals; D000927:Anticonvulsants; D000928:Antidepressive Agents / Q000138:chemical synthesis / Q000494:pharmacology / Q000633:toxicity; D001381:Azepines; D001522:Behavior, Animal; D001794:Blood Pressure / Q000187:drug effects; D002247:Carbon Isotopes; D055598:Chemical Phenomena; D002621:Chemistry; D004295:Dihydroxyphenylalanine / Q000494:pharmacology; D004298:Dopamine / Q000378:metabolism; D004357:Drug Synergism; D005260:Female; D005769:Gastrointestinal Motility; D006168:Guinea Pigs; D006634:Histamine H1 Antagonists; D008297:Male; D051379:Mice; D008996:Monoamine Oxidase Inhibitors; D009638:Norepinephrine / Q000494:pharmacology; D010862:Pilocarpine; D011437:Propylamines; D051381:Rats; D012110:Reserpine / Q000037:antagonists & inhibitors; D014203:Tremorine
D000927:Anticonvulsants; D000928:Antidepressive Agents; D001381:Azepines; D002247:Carbon Isotopes; D006634:Histamine H1 Antagonists; D008996:Monoamine Oxidase Inhibitors; D011437:Propylamines; D010862:Pilocarpine; D004295:Dihydroxyphenylalanine; D012110:Reserpine; D014203:Tremorine; D004298:Dopamine; D009638:Norepinephrine