title: Antihypertensive agents. II. Synthesis and hypotensive activity of certain 1,4,5-trisubstituted pyrazoles.
mesh_terms: D000109:Acetylcholine / Q000037:antagonists & inhibitors; D000661:Amphetamine / Q000037:antagonists & inhibitors; D000804:Angiotensin II / Q000037:antagonists & inhibitors; D000818:Animals; D000959:Antihypertensive Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D002415:Cats; D004285:Dogs; D005260:Female; D006168:Guinea Pigs; D006339:Heart Rate / Q000187:drug effects; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects; D009541:Nictitating Membrane / Q000187:drug effects; D009638:Norepinephrine / Q000494:pharmacology; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D012702:Serotonin Antagonists; D013053:Spectrophotometry; D014466:Ultraviolet Rays
chemical_list: D000959:Antihypertensive Agents; D006634:Histamine H1 Antagonists; D011720:Pyrazoles; D012702:Serotonin Antagonists; D000804:Angiotensin II; D012110:Reserpine; D000661:Amphetamine; D000109:Acetylcholine; D009638:Norepinephrine