Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 1. Structure-activity relationships of agonists and antagonists of biogenic amines and of tricyclic tranquilizers and antidepressants.
D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry / Q000187:drug effects; D002247:Carbon Isotopes; D002395:Catecholamines / Q000494:pharmacology*; D002540:Cerebral Cortex / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism*; D004837:Epinephrine / Q000494:pharmacology; D006168:Guinea Pigs; D006213:Hallucinogens / Q000494:pharmacology; D006632:Histamine / Q000494:pharmacology*; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D066298:In Vitro Techniques; D007545:Isoproterenol / Q000494:pharmacology; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D014149:Tranquilizing Agents / Q000494:pharmacology*
D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D000928:Antidepressive Agents; D002247:Carbon Isotopes; D002395:Catecholamines; D006213:Hallucinogens; D006634:Histamine H1 Antagonists; D008996:Monoamine Oxidase Inhibitors; D014149:Tranquilizing Agents; D012701:Serotonin; D006632:Histamine; D000242:Cyclic AMP; D007545:Isoproterenol; D009638:Norepinephrine; D004837:Epinephrine