title: Insulin secretion from toadfish islet tissue stimulated by pyridine nucleotides.
abstract: The addition of glucose stimulated release of insulin from the isolated islet tissue of the toadfish incubated in vitro. Reduced nicotinamide-adenine dinucleotide also stimulated insulin release, whereas the oxidized form had no effect. Both oxidized and reduced nicotinamide-adenine dinucleatide phosphate stimulated insulin release, but the reduced form was significantly more effective.
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects; D000818:Animals; D001681:Biological Assay; D005399:Fishes; D005947:Glucose / Q000494:pharmacology; D066298:In Vitro Techniques; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism*; D009243:NAD / Q000494:pharmacology*; D009249:NADP / Q000494:pharmacology*; D010084:Oxidation-Reduction; D013053:Spectrophotometry
chemical_list: D007328:Insulin; D009243:NAD; D009249:NADP; D005947:Glucose