title: Aryl hydrocarbon (benzopyrene) hydroxylase is stimulated in human lymphocytes by mitogens and benz(a)anthracene.
abstract: A mixed-function oxidase that requires reduced nicotinamide adenine dinucleotide phosphate, is carbon monoxide sensitive, and is drug-metabolizing is present in human lymphocytes and is increased to different levels by treatment with phytohemagglutinin, pokeweed mitogen, and a polycyclic hydrocarbon.
mesh_terms: D001551:Benz(a)Anthracenes / Q000494:pharmacology*; D001580:Benzopyrenes; D002248:Carbon Monoxide / Q000494:pharmacology; D004790:Enzyme Induction; D006801:Humans; D006838:Hydrocarbons / Q000494:pharmacology; D066298:In Vitro Techniques; D037102:Lectins / Q000494:pharmacology; D008214:Lymphocytes / Q000201:enzymology*; D008938:Mitosis / Q000187:drug effects*; D006899:Mixed Function Oxygenases / Q000097:blood*; D009249:NADP / Q000378:metabolism; D037121:Plant Lectins; D010944:Plants
chemical_list: D001551:Benz(a)Anthracenes; D001580:Benzopyrenes; D006838:Hydrocarbons; D037102:Lectins; D037121:Plant Lectins; D009249:NADP; D002248:Carbon Monoxide; D006899:Mixed Function Oxygenases