title: Supersensitivity and dependence.
mesh_terms: D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D004361:Drug Tolerance; D006632:Histamine / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D008960:Models, Psychological; D009020:Morphine; D009411:Nerve Endings / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects; D018377:Neurotransmitter Agents / Q000502:physiology*; D011600:Psychopharmacology; D011678:Punishment; D011955:Receptors, Drug; D012201:Reward; D012653:Self Stimulation; D012701:Serotonin / Q000502:physiology; D013375:Substance Withdrawal Syndrome; D019966:Substance-Related Disorders; D009435:Synaptic Transmission / Q000187:drug effects
chemical_list: D018377:Neurotransmitter Agents; D011955:Receptors, Drug; D012701:Serotonin; D009020:Morphine; D006632:Histamine; D000109:Acetylcholine