Genetic and biochemical properties of thymidine-dependent mutants of pneumococcus.
Independently isolated thymidine-dependent strains were shown to be defective in thymidylate synthetase and mutated at separable but closely linked sites.
D003433:Crosses, Genetic; D003470:Culture Media; D004269:DNA, Bacterial; D005827:Genetics, Microbial; D008025:Ligases / Q000378:metabolism; D009154:Mutation; D011995:Recombination, Genetic; D013053:Spectrophotometry; D013296:Streptococcus pneumoniae / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*; D013936:Thymidine / Q000378:metabolism*; D013942:Thymine Nucleotides; D014170:Transformation, Genetic
D003470:Culture Media; D004269:DNA, Bacterial; D013942:Thymine Nucleotides; D008025:Ligases; D013936:Thymidine