title: 4,4,6-trimethyl-3,4-dihydropyrimidine-2-thiol, an effective inhibitor of dopamine-beta-hydroxylation in vivo.
mesh_terms: D000079:Acetaldehyde / Q000378:metabolism; D000605:Amino Alcohols / Q000494:pharmacology; D000818:Animals; D001593:Benzyl Compounds / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D001923:Brain Chemistry / Q000187:drug effects*; D002247:Carbon Isotopes; D002417:Cattle; D004295:Dihydroxyphenylalanine / Q000494:pharmacology; D004221:Disulfiram / Q000494:pharmacology; D004298:Dopamine / Q000378:metabolism; D000431:Ethanol / Q000378:metabolism; D005021:Ethylamines / Q000494:pharmacology; D005260:Female; D006321:Heart / Q000187:drug effects; D006834:Hydrazines / Q000494:pharmacology; D007455:Iodine / Q000378:metabolism; D008297:Male; D008680:Metaraminol / Q000494:pharmacology; D008750:Methyldopa / Q000494:pharmacology; D008781:Methyltyrosines / Q000494:pharmacology; D051379:Mice; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors*; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D009206:Myocardium / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D009647:Normetanephrine / Q000494:pharmacology; D011441:Propylthiouracil / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology*; D051381:Rats; D012110:Reserpine / Q000494:pharmacology; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000494:pharmacology; D013961:Thyroid Gland / Q000187:drug effects / Q000378:metabolism; D014439:Tyramine / Q000494:pharmacology
chemical_list: D000605:Amino Alcohols; D001593:Benzyl Compounds; D002247:Carbon Isotopes; D005021:Ethylamines; D006834:Hydrazines; D008781:Methyltyrosines; D008996:Monoamine Oxidase Inhibitors; D011743:Pyrimidines; D013438:Sulfhydryl Compounds; D009647:Normetanephrine; D000431:Ethanol; D008750:Methyldopa; D004295:Dihydroxyphenylalanine; D011441:Propylthiouracil; D008680:Metaraminol; D012110:Reserpine; D007455:Iodine; D006899:Mixed Function Oxygenases; D000079:Acetaldehyde; D004221:Disulfiram; D004298:Dopamine; D009638:Norepinephrine; D014439:Tyramine