Some studies and comments on hepatic and extrahepatic microsomal toxication-detoxication systems. A limited discussion of some of the heterogeneities of these systems and of their responses to stimulation of enzyme "induction".
D000367:Age Factors; D000818:Animals; D001580:Benzopyrenes / Q000494:pharmacology; D002458:Cell Fractionation; D003580:Cytochromes; D003634:DDT / Q000494:pharmacology; D004790:Enzyme Induction / Q000187:drug effects; D008099:Liver / Q000166:cytology / Q000378:metabolism*; D008168:Lung / Q000166:cytology / Q000378:metabolism*; D051379:Mice; D008815:Mice, Inbred Strains; D008861:Microsomes / Q000201:enzymology*; D008862:Microsomes, Liver / Q000201:enzymology; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010634:Phenobarbital / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D013045:Species Specificity; D013268:Stimulation, Chemical; D014116:Toxicology
D001580:Benzopyrenes; D003580:Cytochromes; D004364:Pharmaceutical Preparations; D003634:DDT; D009247:NADH, NADPH Oxidoreductases; D010634:Phenobarbital