The conversion of pyrrolizidine alkaloids to N-oxides and to dihydropyrrolizine derivatives by rat-liver microsomes in vitro.
D000470:Alkaloids / Q000378:metabolism*; D000818:Animals; D002118:Calcium; D002248:Carbon Monoxide / Q000494:pharmacology; D003634:DDT / Q000494:pharmacology; D004032:Diet; D007700:Kinetics; D008168:Lung / Q000166:cytology; D008274:Magnesium; D008345:Manganese; D008861:Microsomes / Q000378:metabolism; D008862:Microsomes, Liver / Q000201:enzymology / Q000378:metabolism*; D008954:Models, Biological; D009249:NADP; D009536:Niacinamide / Q000494:pharmacology; D010087:Oxides / Q000096:biosynthesis*; D010100:Oxygen / Q000494:pharmacology; D010634:Phenobarbital / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D011506:Proteins; D011758:Pyrroles; D011763:Pyrrolizidine Alkaloids / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains
D000470:Alkaloids; D010087:Oxides; D011506:Proteins; D011758:Pyrroles; D011763:Pyrrolizidine Alkaloids; D009536:Niacinamide; D008345:Manganese; D009249:NADP; D002248:Carbon Monoxide; D011335:Proadifen; D003634:DDT; D008274:Magnesium; D010100:Oxygen; D002118:Calcium; D010634:Phenobarbital