Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. I. Tricyclic tertiary amine drugs.
D000639:Amitriptyline / Q000378:metabolism; D000818:Animals; D002247:Carbon Isotopes; D002248:Carbon Monoxide / Q000494:pharmacology; D002746:Chlorpromazine / Q000378:metabolism; D003497:Cyclic N-Oxides / Q000378:metabolism; D003580:Cytochromes / Q000494:pharmacology; D003640:Dealkylation; D003891:Desipramine / Q000096:biosynthesis; D006736:Horses; D007099:Imipramine / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D009249:NADP / Q000494:pharmacology; D009928:Organ Specificity; D010084:Oxidation-Reduction; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D013045:Species Specificity; D013347:Subcellular Fractions / Q000378:metabolism; D013552:Swine; D013778:Tetrazolium Salts / Q000494:pharmacology
D002247:Carbon Isotopes; D003497:Cyclic N-Oxides; D003580:Cytochromes; D013778:Tetrazolium Salts; D000639:Amitriptyline; D009249:NADP; D002248:Carbon Monoxide; D011335:Proadifen; D007099:Imipramine; D003891:Desipramine; D002746:Chlorpromazine