Blockade of heart 3H-norepinephrine up-take by 4-phenyl-1-aminotetralines: implications for the active conformation of imipramine-like drugs.
D000588:Amines / Q000008:administration & dosage / Q000494:pharmacology; D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D003461:Crystallography; D003864:Depression, Chemical; D003891:Desipramine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D007099:Imipramine; D008297:Male; D051379:Mice; D008968:Molecular Conformation; D009206:Myocardium / Q000378:metabolism*; D009281:Naphthalenes / Q000008:administration & dosage / Q000494:pharmacology*; D009638:Norepinephrine / Q000037:antagonists & inhibitors / Q000378:metabolism*; D051381:Rats; D012110:Reserpine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013997:Time Factors; D014316:Tritium
D000588:Amines; D009281:Naphthalenes; D014316:Tritium; D012110:Reserpine; D007099:Imipramine; D003891:Desipramine; D009638:Norepinephrine