Dimethylbiguanide-evoked increase of anticoagulant elimination not associated with induction of drug metabolizing enzymes.
D000633:Aminopyrine N-Demethylase / Q000378:metabolism*; D000818:Animals; D001580:Benzopyrenes; D001835:Body Weight; D002250:Carbon Radioisotopes; D002855:Chromatography, Thin Layer; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004790:Enzyme Induction / Q000187:drug effects; D004852:Epoxy Compounds; D006836:Hydro-Lyases / Q000378:metabolism*; D008297:Male; D008687:Metformin / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D009929:Organ Size; D051381:Rats; D013050:Spectrometry, Fluorescence; D013053:Spectrophotometry; D013997:Time Factors; D014316:Tritium
D001580:Benzopyrenes; D002250:Carbon Radioisotopes; D004852:Epoxy Compounds; D014316:Tritium; D003577:Cytochrome P-450 Enzyme System; D008687:Metformin; D000633:Aminopyrine N-Demethylase; D006836:Hydro-Lyases