Metabolism of 6-chloro-5-cyclohexylindan-1-carboxylic acid (TAI-284), a new non-steroidal anti-inflammatory agent, in relation to ulcerogenic activity.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D001646:Bile / Q000378:metabolism; D002264:Carboxylic Acids / Q000378:metabolism* / Q000494:pharmacology; D003510:Cyclohexanes / Q000031:analogs & derivatives / Q000378:metabolism; D003600:Cytosol / Q000378:metabolism; D005260:Female; D005965:Glucuronates / Q000378:metabolism; D005966:Glucuronidase; D006168:Guinea Pigs; D006863:Hydrogen-Ion Concentration; D007189:Indans / Q000378:metabolism* / Q000494:pharmacology; D007192:Indenes / Q000378:metabolism*; D007421:Intestine, Small / Q000187:drug effects; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008862:Microsomes, Liver / Q000378:metabolism; D010437:Peptic Ulcer / Q000139:chemically induced*; D010634:Phenobarbital / Q000494:pharmacology; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D014316:Tritium; D014539:Uridine Diphosphate Sugars / Q000494:pharmacology
D000893:Anti-Inflammatory Agents; D002264:Carboxylic Acids; D003510:Cyclohexanes; D005965:Glucuronates; D007189:Indans; D007192:Indenes; D014539:Uridine Diphosphate Sugars; D014316:Tritium; D011335:Proadifen; D005966:Glucuronidase; D010634:Phenobarbital