Aporphines. 11. Synthesis and dopaminergic acitivity of monohydroxyaporphines. Total synthesis of (plus, minus)-11-hydroxyaporphine, (plus and minus)-11-hydroxynoraporphine, and (plus, minus)-11-hydroxy-N-n-propylnoraporphine.
D000818:Animals; D001060:Aporphines / Q000138:chemical synthesis* / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects; D004298:Dopamine / Q000502:physiology; D005106:Exploratory Behavior / Q000187:drug effects; D006892:Hydroxydopamines / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008856:Microscopy, Fluorescence; D009043:Motor Activity / Q000187:drug effects; D009904:Optical Rotation; D051381:Rats; D011955:Receptors, Drug; D012399:Rotation; D013055:Spectrophotometry, Infrared; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013378:Substantia Nigra / Q000166:cytology / Q000502:physiology
D001060:Aporphines; D006892:Hydroxydopamines; D011955:Receptors, Drug; C007984:11-hydroxyaporphine; C008081:11-hydroxy-N-(n-propyl)noraporphine; D004298:Dopamine