Inhibition of pyruvate and beta-hydroxybutyrate oxidation in rat brain mitochondria by phenylpyruvate and alpha-ketoisocaproate.
D000818:Animals; D001921:Brain / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D002208:Caproates / Q000494:pharmacology*; D002934:Cinnamates / Q000494:pharmacology; D003486:Cyanides / Q000494:pharmacology; D005971:Glutamates / Q000378:metabolism; D006884:Hydroxybutyrate Dehydrogenase / Q000378:metabolism; D006885:Hydroxybutyrates / Q000378:metabolism*; D007651:Keto Acids / Q000494:pharmacology*; D007700:Kinetics; D008293:Malates / Q000378:metabolism; D008297:Male; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010101:Oxygen Consumption / Q000187:drug effects*; D010667:Phenylpyruvic Acids / Q000494:pharmacology*; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism; D011773:Pyruvates; D051381:Rats; D013386:Succinates / Q000378:metabolism
D002208:Caproates; D002934:Cinnamates; D003486:Cyanides; D005971:Glutamates; D006885:Hydroxybutyrates; D007651:Keto Acids; D008293:Malates; D010667:Phenylpyruvic Acids; D011768:Pyruvate Dehydrogenase Complex; D011773:Pyruvates; D013386:Succinates; D006884:Hydroxybutyrate Dehydrogenase