The phenyl rings of tricyclic antidepressants and related compounds as determinants of the potency of inhibition of the amine pumps in adrenergic neurons of the rabbit aorta and in rat cortical synaptosomes.
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001011:Aorta / Q000294:innervation / Q000378:metabolism*; D001679:Biogenic Amines / Q000378:metabolism*; D002540:Cerebral Cortex / Q000648:ultrastructure; D003891:Desipramine / Q000031:analogs & derivatives / Q000494:pharmacology; D003986:Dibenzocycloheptenes / Q000494:pharmacology; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008968:Molecular Conformation; D009474:Neurons / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D010525:Peripheral Nerves / Q000378:metabolism; D011437:Propylamines / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D013329:Structure-Activity Relationship; D013564:Sympathetic Nervous System / Q000378:metabolism*; D013574:Synaptosomes / Q000378:metabolism*; D014316:Tritium
D000928:Antidepressive Agents; D001679:Biogenic Amines; D003986:Dibenzocycloheptenes; D011437:Propylamines; D014316:Tritium; D003891:Desipramine; D009638:Norepinephrine