Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VI. Different substrate specificities of the cytochrome P450 fractions from control and phenobarbital-treated rats.
D000814:Aniline Compounds / Q000378:metabolism; D000818:Animals; D001580:Benzopyrenes / Q000378:metabolism; D001589:Benzphetamine / Q000378:metabolism; D055598:Chemical Phenomena; D002621:Chemistry; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003640:Dealkylation; D004305:Dose-Response Relationship, Drug; D005419:Flavonoids / Q000494:pharmacology; D006420:Hemeproteins / Q000302:isolation & purification; D006900:Hydroxylation; D008055:Lipids; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000378:metabolism*; D009019:Morphinans / Q000378:metabolism; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D010424:Pentobarbital / Q000378:metabolism; D010634:Phenobarbital / Q000494:pharmacology*; D010879:Piperazines / Q000378:metabolism; D011335:Proadifen / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship; D013739:Testosterone / Q000378:metabolism
D000814:Aniline Compounds; D001580:Benzopyrenes; D005419:Flavonoids; D006420:Hemeproteins; D008055:Lipids; D009019:Morphinans; D010879:Piperazines; D001589:Benzphetamine; D013739:Testosterone; D008748:Methylcholanthrene; D003577:Cytochrome P-450 Enzyme System; D011335:Proadifen; D010089:Oxidoreductases, N-Demethylating; D010424:Pentobarbital; D010634:Phenobarbital