A comparison of the effects of alkylating agents 1,3-bis(2-chloroethyl)-1-nitrosourea, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and nitrogen mustard on nuclear RNA synthesis and processing.
D000241:Adenosine; D000477:Alkylating Agents / Q000494:pharmacology*; D002330:Carmustine / Q000494:pharmacology*; D002466:Cell Nucleolus / Q000378:metabolism; D002467:Cell Nucleus / Q000187:drug effects / Q000378:metabolism; D002846:Chromatography, Affinity; D003593:Cytoplasm / Q000187:drug effects / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D006367:HeLa Cells / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D046911:Macromolecular Substances; D008466:Mechlorethamine / Q000494:pharmacology*; D009607:Nitrosourea Compounds / Q000494:pharmacology*; D010179:Pancreas / Q000201:enzymology; D012313:RNA / Q000096:biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D012334:RNA, Neoplasm / Q000378:metabolism*; D012335:RNA, Ribosomal / Q000096:biosynthesis; D012260:Ribonucleases; D014316:Tritium; D014529:Uridine
D000477:Alkylating Agents; D046911:Macromolecular Substances; D009607:Nitrosourea Compounds; D012333:RNA, Messenger; D012334:RNA, Neoplasm; D012335:RNA, Ribosomal; D014316:Tritium; D008466:Mechlorethamine; D012313:RNA; D012260:Ribonucleases; D000241:Adenosine; D002330:Carmustine; D014529:Uridine