A rapid, simple assay for digoxin.
An extremely rapid radioimmunoassay for digoxin is described which is precise over the range of concentrations required to determine whether, or not, a patient has digoxin toxicity. The assay is based on the use of (125)-iodine-labelled digoxin and of a gel equilibration technique for the separation of antibody-bound and free digoxin. The results obtained compare closely with those by a conventional radioimmunoassay and the technique is sufficiently simple to enable its performance by relatively inexperienced laboratory staff.
D001666:Binding Sites, Antibody; D004077:Digoxin / Q000097:blood* / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D007457:Iodine Radioisotopes; D011863:Radioimmunoassay / Q000379:methods
D007106:Immune Sera; D007457:Iodine Radioisotopes; D004077:Digoxin