Inhibition of entry of some amino acids into the brain, with observations on mental retardation in the aminoacidurias.
D000367:Age Factors; D000592:Amino Acid Metabolism, Inborn Errors / Q000150:complications / Q000178:diet therapy*; D000596:Amino Acids / Q000097:blood* / Q000494:pharmacology; D000818:Animals; D001120:Arginine / Q000378:metabolism; D001693:Biological Transport, Active / Q000187:drug effects; D001921:Brain / Q000378:metabolism*; D002208:Caproates / Q000494:pharmacology; D002250:Carbon Radioisotopes; D003864:Depression, Chemical; D004347:Drug Interactions; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000517:prevention & control*; D007532:Isoleucine / Q000378:metabolism; D007651:Keto Acids / Q000494:pharmacology; D007930:Leucine / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013268:Stimulation, Chemical; D013912:Threonine / Q000378:metabolism
D000596:Amino Acids; D002208:Caproates; D002250:Carbon Radioisotopes; D007651:Keto Acids; D007532:Isoleucine; D013912:Threonine; D001120:Arginine; D007930:Leucine