Potential antiinflammatory agents. II. Synthesis and structure-activity relationships of 6-chloro-5-cyclohexylindan-1-carboxylic acid (TAI-284) and related 5-substituted indan-1-carboxylic acids.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D002264:Carboxylic Acids / Q000138:chemical synthesis / Q000627:therapeutic use / Q000633:toxicity; D003510:Cyclohexanes / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000627:therapeutic use / Q000633:toxicity; D004487:Edema / Q000188:drug therapy; D007192:Indenes / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D007928:Lethal Dose 50; D051381:Rats; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000893:Anti-Inflammatory Agents; D002264:Carboxylic Acids; D003510:Cyclohexanes; D007192:Indenes