The role of aryl hydrocarbon hydroxylase in skin tumor initiation by 7,12-dimethylbenz(a)anthracene and 1,2,5,6-dibenzanthracene using DNA binding and thymidine-3H incorporation into DNA as criteria.
D000287:Administration, Topical; D000818:Animals; D001551:Benz(a)Anthracenes / Q000037:antagonists & inhibitors / Q000378:metabolism; D002273:Carcinogens; D004247:DNA / Q000096:biosynthesis / Q000378:metabolism; D004273:DNA, Neoplasm / Q000096:biosynthesis; D005260:Female; D005419:Flavonoids / Q000494:pharmacology; D051379:Mice; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D010634:Phenobarbital / Q000494:pharmacology; D011083:Polycyclic Compounds; D011506:Proteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D012867:Skin / Q000378:metabolism; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000201:enzymology; D013936:Thymidine / Q000378:metabolism; D014316:Tritium
D001551:Benz(a)Anthracenes; D002273:Carcinogens; D004273:DNA, Neoplasm; D005419:Flavonoids; D011083:Polycyclic Compounds; D011506:Proteins; D014316:Tritium; D012313:RNA; D004247:DNA; D006899:Mixed Function Oxygenases; D013936:Thymidine; D010634:Phenobarbital