title: Thyroid hormone response to prolonged cold exposure in man.
abstract: 1. Four men, of ages varying from 23 to 28 years, living at Halley Bay, Antarctica (75 degrees 31' S, 26 degrees 39' W), were exposed to a mean air temperature of 6.6 degrees C.2. The concentration of serum triiodothyronine (T(3)) rose significantly by the second day, remained raised, and returned to pre-exposure levels within 2 days of return to a normal environment.3. The concentration of serum thyroxine (T(4)) rose more slowly than did the T(3), reaching a maximum in 3-4 days and also returning to normal within 2 days of return to a normal environment.4. There was a wide individual variation in the change of concentration of serum cortisol.
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D000864:Antarctic Regions; D003080:Cold Temperature; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D011863:Radioimmunoassay; D013974:Thyroxine / Q000097:blood*; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood*
chemical_list: D014284:Triiodothyronine; D013974:Thyroxine; D006854:Hydrocortisone