Comparative evaluation of the central nervous system activity of diazepam and its metabolites (demethyl-diazepam, methyl-oxazepam and oxazepam).
D000818:Animals; D002490:Central Nervous System / Q000187:drug effects*; D003640:Dealkylation; D003975:Diazepam / Q000031:analogs & derivatives* / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D005260:Female; D006591:Hexobarbital / Q000494:pharmacology; D006900:Hydroxylation; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009125:Muscle Relaxants, Central / Q000494:pharmacology; D009132:Muscles / Q000187:drug effects; D010076:Oxazepam / Q000031:analogs & derivatives* / Q000494:pharmacology*; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D012890:Sleep / Q000187:drug effects; D013331:Strychnine / Q000037:antagonists & inhibitors; D013997:Time Factors
D009125:Muscle Relaxants, Central; D010076:Oxazepam; D006591:Hexobarbital; D013331:Strychnine; D003975:Diazepam; D010433:Pentylenetetrazole