title: Pyrrolo(4,3,2-de)isoquinolines with central nervous system and antihypertensive activities.
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001763:Blepharoptosis / Q000139:chemically induced; D001794:Blood Pressure / Q000187:drug effects; D001921:Brain / Q000187:drug effects / Q000201:enzymology; D002490:Central Nervous System / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000037:antagonists & inhibitors; D005260:Female; D007274:Injections, Intraperitoneal; D007546:Isoquinolines / Q000494:pharmacology*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D009206:Myocardium / Q000201:enzymology; D011758:Pyrroles / Q000494:pharmacology; D051381:Rats; D012110:Reserpine / Q000037:antagonists & inhibitors; D014439:Tyramine / Q000494:pharmacology
chemical_list: D000959:Antihypertensive Agents; D007546:Isoquinolines; D008996:Monoamine Oxidase Inhibitors; D011758:Pyrroles; D012110:Reserpine; D014439:Tyramine; D004837:Epinephrine