The mechanism of aconitase action. Evidence for an enzyme isomerization by studies of inhibition by tricarboxylic acids.
D000154:Aconitate Hydratase / Q000037:antagonists & inhibitors*; D000156:Aconitic Acid / Q000494:pharmacology; D001665:Binding Sites; D001667:Binding, Competitive; D002951:Citrates / Q000494:pharmacology; D005461:Fluorine; D006836:Hydro-Lyases / Q000037:antagonists & inhibitors*; D007523:Isocitrates / Q000494:pharmacology; D007536:Isomerism; D007700:Kinetics; D008433:Mathematics; D010071:Oxaloacetates / Q000494:pharmacology; D011485:Protein Binding; D013056:Spectrophotometry, Ultraviolet; D013329:Structure-Activity Relationship; D014233:Tricarboxylic Acids / Q000494:pharmacology*
D002951:Citrates; D007523:Isocitrates; D010071:Oxaloacetates; D014233:Tricarboxylic Acids; D005461:Fluorine; D000156:Aconitic Acid; D006836:Hydro-Lyases; D000154:Aconitate Hydratase