title: Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.
mesh_terms: D000082:Acetaminophen / Q000009:adverse effects / Q000097:blood / Q000378:metabolism / Q000652:urine; D000111:Acetylcysteine / Q000652:urine; D000328:Adult; D000654:Amobarbital / Q000494:pharmacology; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000517:prevention & control*; D002854:Chromatography, Paper; D003543:Cysteamine / Q000627:therapeutic use; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003891:Desipramine / Q000494:pharmacology; D004112:Dimercaprol / Q000652:urine; D004305:Dose-Response Relationship, Drug; D004790:Enzyme Induction / Q000187:drug effects; D005260:Female; D005978:Glutathione / Q000627:therapeutic use*; D006801:Humans; D007202:Indicators and Reagents; D008099:Liver / Q000378:metabolism; D008297:Male; D013058:Mass Spectrometry; D008780:Methyltransferases / Q000378:metabolism; D051379:Mice; D008862:Microsomes, Liver / Q000201:enzymology; D010634:Phenobarbital / Q000494:pharmacology; D011485:Protein Binding / Q000187:drug effects; D011506:Proteins / Q000378:metabolism; D013438:Sulfhydryl Compounds / Q000627:therapeutic use; D013997:Time Factors; D014316:Tritium
chemical_list: D007202:Indicators and Reagents; D011506:Proteins; D013438:Sulfhydryl Compounds; D004112:Dimercaprol; D014316:Tritium; D000082:Acetaminophen; D003543:Cysteamine; D003577:Cytochrome P-450 Enzyme System; D008780:Methyltransferases; D005978:Glutathione; D000654:Amobarbital; D003891:Desipramine; D000111:Acetylcysteine; D010634:Phenobarbital