A duodenal role in gastrin release.
Observations on the plasma gastrin response to feeding protein in patients with the dumping syndrome, patients with pyloric stenosis, and patients asymptomatic after gastric surgery suggested that the duodenum might be important in the mechanism of gastrin release. This duodenal role was confirmed by the finding that when the stimulus was placed directly in the duodenum peak gastrin levels occurred earlier than when the stimulus was placed directly in the stomach.
D004044:Dietary Proteins; D004377:Dumping Syndrome / Q000503:physiopathology; D004381:Duodenal Ulcer / Q000503:physiopathology; D004386:Duodenum / Q000502:physiology* / Q000503:physiopathology; D005755:Gastrins / Q000378:metabolism*; D006801:Humans; D011707:Pyloric Stenosis / Q000503:physiopathology; D012636:Secretory Rate; D013997:Time Factors; D014628:Vagotomy
D004044:Dietary Proteins; D005755:Gastrins