Early differential effects of 3-methylcholanthrene and its "K-region" epoxide on mouse skin. Possible implication in the two-stage mechanism of tumorigenesis.
D000287:Administration, Topical; D000818:Animals; D001345:Autoradiography; D001580:Benzopyrenes; D004988:Ethers, Cyclic / Q000494:pharmacology; D006843:Hydrocarbons, Chlorinated / Q000494:pharmacology; D006965:Hyperplasia / Q000473:pathology; D006984:Hypertrophy / Q000473:pathology; D008297:Male; D008748:Methylcholanthrene / Q000031:analogs & derivatives* / Q000633:toxicity*; D051379:Mice; D008807:Mice, Inbred BALB C; D008938:Mitosis; D006899:Mixed Function Oxygenases / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000139:chemically induced / Q000201:enzymology / Q000473:pathology; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000201:enzymology / Q000473:pathology; D013997:Time Factors
D001580:Benzopyrenes; D004988:Ethers, Cyclic; D006843:Hydrocarbons, Chlorinated; D008748:Methylcholanthrene; D006899:Mixed Function Oxygenases