X-accumulation of labelled aminotriazole in some transplanted tumours in mice.
Autoradiography with (14)C-labelled aminotriazole (3-amino-1,2,4-triazole) was performed in mice with transplanted tumours. A high accumulation of radioactivity was demonstrated in the tumours, the uptake being the highest in the actively growing parts. The possible mechanism involved is discussed.
D000818:Animals; D001345:Autoradiography; D002250:Carbon Radioisotopes; D002277:Carcinoma / Q000378:metabolism; D005354:Fibrosarcoma / Q000378:metabolism; D007422:Intestines / Q000032:analysis; D007668:Kidney / Q000032:analysis; D008099:Liver / Q000032:analysis; D008223:Lymphoma / Q000378:metabolism; D008325:Mammary Neoplasms, Experimental / Q000378:metabolism; D051379:Mice; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000378:metabolism* / Q000473:pathology; D013154:Spleen / Q000032:analysis; D013997:Time Factors; D014184:Transplantation, Homologous; D014230:Triazoles / Q000032:analysis / Q000097:blood / Q000378:metabolism*
D002250:Carbon Radioisotopes; D014230:Triazoles