Effect of phenobarbital on the level of gossypol in the liver and the effect of gossypol and phenobarbital on liver microsomal O-demethylation and lipid peroxidation activities in the rat.
D000818:Animals; D000840:Anisoles / Q000378:metabolism; D003640:Dealkylation; D004305:Dose-Response Relationship, Drug; D006072:Gossypol / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology; D007274:Injections, Intraperitoneal; D007441:Intubation, Gastrointestinal; D007501:Iron / Q000494:pharmacology; D050356:Lipid Metabolism; D008099:Liver / Q000033:anatomy & histology / Q000187:drug effects; D008862:Microsomes, Liver / Q000378:metabolism*; D009574:Nitro Compounds / Q000378:metabolism; D009929:Organ Size; D010084:Oxidation-Reduction; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D010545:Peroxides / Q000378:metabolism; D010634:Phenobarbital / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D012964:Sodium / Q000494:pharmacology
D000840:Anisoles; D009574:Nitro Compounds; D010545:Peroxides; D012964:Sodium; D007501:Iron; D010089:Oxidoreductases, N-Demethylating; D006072:Gossypol; D010634:Phenobarbital