title: Non-specificity of laboratory test for diagnosis of multiple sclerosis.
abstract: It has been claimed that the inhibiting effect of linoleic acid on the macrophage electrophoretic mobility test provides a specific laboratory method for the diagnosis of multiple sclerosis (M.S.) and may also enable susceptible relatives of M.S. patients to be identified. Three trials of the method under double-blind conditions have failed to confirm that the test is diagnostically useful.
mesh_terms: D000818:Animals; D002464:Cell Migration Inhibition / Q000379:methods; D003951:Diagnostic Errors; D004586:Electrophoresis; D006168:Guinea Pigs; D006801:Humans; D008041:Linoleic Acids / Q000494:pharmacology; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000276:immunology
chemical_list: D008041:Linoleic Acids