title: Investigation of the effects of methyltestosterone, cortisone and spironolactone on the hepatic microsomal mixed function oxidase system in male and female rats.
mesh_terms: D000818:Animals; D003348:Cortisone / Q000008:administration & dosage / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000032:analysis; D003579:Cytochrome Reductases / Q000378:metabolism; D005260:Female; D006591:Hexobarbital / Q000378:metabolism; D007700:Kinetics; D008297:Male; D008777:Methyltestosterone / Q000008:administration & dosage / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D009019:Morphinans / Q000378:metabolism; D009249:NADP / Q000378:metabolism; D009929:Organ Size; D010088:Oxidoreductases / Q000378:metabolism*; D011485:Protein Binding; D051381:Rats; D012669:Seminal Vesicles / Q000187:drug effects; D012737:Sex Factors; D013148:Spironolactone / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D014599:Uterus / Q000187:drug effects
chemical_list: D009019:Morphinans; D013148:Spironolactone; D009249:NADP; D003577:Cytochrome P-450 Enzyme System; D006591:Hexobarbital; D010088:Oxidoreductases; D003579:Cytochrome Reductases; D003348:Cortisone; D008777:Methyltestosterone