Synthesis and antiarrhythmic activity of 5,5-disubstituted-3-aminoalkylhydantions and some heterocyclic and noncyclic analogues.
D000478:Alkylation; D000577:Amides / Q000138:chemical synthesis; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D004048:Diethylamines; D004123:Dimethylamines; D004206:Disopyramide / Q000138:chemical synthesis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis; D006827:Hydantoins / Q000138:chemical synthesis* / Q000627:therapeutic use; D007536:Isomerism; D051379:Mice; D010880:Piperidines / Q000138:chemical synthesis; D011802:Quinidine / Q000627:therapeutic use; D013329:Structure-Activity Relationship; D014508:Urea / Q000138:chemical synthesis; D014693:Ventricular Fibrillation / Q000188:drug therapy
D000577:Amides; D004048:Diethylamines; D004123:Dimethylamines; D006571:Heterocyclic Compounds; D006827:Hydantoins; D010880:Piperidines; D014508:Urea; D004206:Disopyramide; D011802:Quinidine