Role of thyroidal lysosomes in the hydrolysis of thyroglobulin and its relation to the development of iodide goiter.
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D002403:Cathepsins / Q000378:metabolism; D002499:Centrifugation, Density Gradient; D005966:Glucuronidase / Q000378:metabolism; D006042:Goiter / Q000209:etiology*; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007454:Iodides / Q000494:pharmacology; D007457:Iodine Radioisotopes; D008247:Lysosomes / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D011092:Polyethylene Glycols / Q000494:pharmacology; D051381:Rats; D013889:Thiouracil / Q000494:pharmacology; D013954:Thyroglobulin / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism / Q000648:ultrastructure*; D013972:Thyrotropin / Q000494:pharmacology; D013974:Thyroxine / Q000494:pharmacology
D007454:Iodides; D007457:Iodine Radioisotopes; D011092:Polyethylene Glycols; D013889:Thiouracil; D013972:Thyrotropin; D013954:Thyroglobulin; D000135:Acid Phosphatase; D005966:Glucuronidase; D002403:Cathepsins; D013974:Thyroxine