Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol.
D000085:Acetates / Q000378:metabolism; D000429:Alcohol Oxidoreductases / Q000037:antagonists & inhibitors*; D002250:Carbon Radioisotopes; D002478:Cells, Cultured; D002648:Child; D002784:Cholesterol / Q000031:analogs & derivatives* / Q000494:pharmacology*; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D005260:Female; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism*; D005977:Glutarates; D006720:Homozygote; D006801:Humans; D006937:Hypercholesterolemia / Q000201:enzymology; D007231:Infant, Newborn; D007664:Ketosteroids / Q000494:pharmacology; D007930:Leucine / Q000378:metabolism; D008055:Lipids / Q000096:biosynthesis; D008297:Male; D008798:Mevalonic Acid / Q000378:metabolism; D014176:Protein Biosynthesis; D013256:Steroids / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014316:Tritium
D000085:Acetates; D002250:Carbon Radioisotopes; D005977:Glutarates; D007664:Ketosteroids; D008055:Lipids; D013256:Steroids; D014316:Tritium; D002784:Cholesterol; D000429:Alcohol Oxidoreductases; D007930:Leucine; D008798:Mevalonic Acid