Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters.
D000082:Acetaminophen / Q000008:administration & dosage / Q000097:blood / Q000633:toxicity*; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D006224:Cricetinae; D003864:Depression, Chemical; D005978:Glutathione / Q000378:metabolism*; D007928:Lethal Dose 50; D008099:Liver / Q000187:drug effects* / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008748:Methylcholanthrene / Q000494:pharmacology; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D009336:Necrosis / Q000139:chemically induced; D010634:Phenobarbital / Q000494:pharmacology; D010882:Piperonyl Butoxide / Q000494:pharmacology; D011485:Protein Binding / Q000187:drug effects; D051381:Rats; D013268:Stimulation, Chemical
D000082:Acetaminophen; D008748:Methylcholanthrene; D005978:Glutathione; D010882:Piperonyl Butoxide; D010634:Phenobarbital