Nodular, non-cirrhotic liver associated with portal hypertension in a patient with rheumatoid arthritis.
A patient with rheumatoid arthritis developed portal hypertension and died from bleeding oesophageal varices. The liver was small and showed a nodular, non-cirrhotic pattern similar to that described by Blendis et al (1970 and 1974) in association with Felty's syndrome. This appears to be the first report of a patient with this liver lesion associated with rheumatoid arthritis in the absence of Felty's syndrome. The liver lesions described here are compared with partial nodular transformation and nodular regenerative hyperplasia; in spite of some differences it is not proven that these are distinct entities and further study is required to settle this question.
D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000473:pathology; D001201:Ascites / Q000150:complications; D003937:Diagnosis, Differential; D005258:Felty Syndrome / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D005385:Fingers / Q000473:pathology; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications* / Q000473:pathology; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000150:complications* / Q000473:pathology; D013163:Splenomegaly / Q000150:complications; D013270:Stomach / Q000473:pathology