Accumulation of an epoxy intermediate during the hepatic microsomal metabolism of cis-stilbene to threo-stilbene glycol due to the inhibition of epoxide hydrolase by trans-stilbenimine.
D000818:Animals; D001388:Aziridines / Q000494:pharmacology; D004852:Epoxy Compounds / Q000378:metabolism*; D004988:Ethers, Cyclic / Q000378:metabolism*; D006018:Glycols / Q000378:metabolism*; D006867:Hydrolases / Q000378:metabolism*; D007700:Kinetics; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D011335:Proadifen / Q000494:pharmacology; D011817:Rabbits; D013267:Stilbenes / Q000378:metabolism*
D001388:Aziridines; D004852:Epoxy Compounds; D004988:Ethers, Cyclic; D006018:Glycols; D013267:Stilbenes; D011335:Proadifen; D006867:Hydrolases