Influence of glucose on the development of experimental metastases.
The effect of 10% glucose solution and narcosis upon the blood borne cancer cells was studied on Wistar rats, with Walker 256 carcinosarcoma inoculated intravenously.Our experiment reveals obvious differences between the control group and the groups treated with glucose concerning incidence, localization and tumour extension, differences which suggest that there is a risk in using glucose in the intra- and post-surgical resuscitation of patients with cancer.
D000310:Adrenal Gland Neoplasms / Q000378:metabolism; D000758:Anesthesia / Q000009:adverse effects; D000818:Animals; D002279:Carcinoma 256, Walker; D005260:Female; D005947:Glucose / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D007275:Injections, Intravenous; D007680:Kidney Neoplasms / Q000378:metabolism; D008175:Lung Neoplasms / Q000378:metabolism; D008207:Lymphatic Metastasis; D009362:Neoplasm Metastasis / Q000209:etiology*; D009368:Neoplasm Transplantation; D009360:Neoplastic Cells, Circulating; D010051:Ovarian Neoplasms / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D005947:Glucose