title: Gene-enzyme relations of tryptophan mutants in Streptomyces coelicolor A3(2).
abstract: Mutations in twenty-eight tryptophan mutants of S. coelicolor A3(2) were mapped relative to the nearest flanking markers. Mutants lacking single enzymatic activities for phosphoribosyltransferase, phosphoribosylanthranilate isomerase, indodeglycerol phosphate synthase, tryptophan synthase A and tryptophan synthase B were identified.
mesh_terms: D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D005796:Genes; D008040:Genetic Linkage; D009154:Mutation; D007652:Oxo-Acid-Lyases / Q000378:metabolism; D010430:Pentosyltransferases / Q000378:metabolism; D013302:Streptomyces / Q000201:enzymology*; D014364:Tryptophan / Q000378:metabolism*; D014367:Tryptophan Synthase / Q000378:metabolism
chemical_list: D014364:Tryptophan; D010430:Pentosyltransferases; D007652:Oxo-Acid-Lyases; D014367:Tryptophan Synthase