The effects of trypsin digested globulin degradation products (TDPG) on the activity of central nervous system.
Studies on trypsin-digested globulin degradation products given to rats intraperitoneally or intraventricularly, revealed psychodepressive effects on the central nervous system. Peptides with a molecular weight of approximately 1,3000 were the most active.
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001920:Bradykinin / Q000008:administration & dosage / Q000494:pharmacology; D002417:Cattle; D002490:Central Nervous System / Q000187:drug effects*; D003864:Depression, Chemical; D008297:Male; D008970:Molecular Weight; D051381:Rats; D012712:Serum Globulins / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors; D014357:Trypsin
D012712:Serum Globulins; D014357:Trypsin; D001920:Bradykinin