Microsomal synthesis of cholesterol from squalene, Lanosterol, and desmosterol. Evidence for the presence of two noncatalytic activator proteins in the 105,000 g supernatant fraction from brain, heart, and kidney.
D000818:Animals; D001921:Brain / Q000378:metabolism; D002784:Cholesterol / Q000096:biosynthesis*; D003897:Desmosterol / Q000378:metabolism*; D004355:Drug Stability; D004789:Enzyme Activation; D006358:Hot Temperature; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D007810:Lanosterol / Q000378:metabolism*; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism; D009928:Organ Specificity; D011506:Proteins / Q000378:metabolism*; D051381:Rats; D013185:Squalene / Q000378:metabolism*; D014357:Trypsin
D011506:Proteins; D007810:Lanosterol; D003897:Desmosterol; D013185:Squalene; D002784:Cholesterol; D014357:Trypsin