[ The radioimmunoassay of prostaglandins F in human plasma and endometrium (author's transl)].
A double antibody radioimmunoassay in estudied for the determination of PGF2alpha. Its sensitivity allows to detect 0.4 ng. The reproductibility in this assays is of 7.8 % while between assays is of 10.7 %. No detectable levels (less than 0.8 ng/ml) could be found on blood obtained from the right heart chambers during the menstrual cycle, but they were measured in peripheral blood during normal deliveries. Changes on PGF2alpha concentrations occur in the endometrium along the menstrual cycle. Tis is a relatively simple method useful either for farmocodinamical studies when administering PGF2alpha or for physiological work with tissure showing relatively high concentrations of this compound.
D000328:Adult; D000906:Antibodies / Q000032:analysis; D036861:Delivery, Obstetric; D004717:Endometrium / Q000032:analysis*; D005260:Female; D006801:Humans; D008598:Menstruation; D011247:Pregnancy; D011460:Prostaglandins F / Q000032:analysis* / Q000097:blood; D011863:Radioimmunoassay
D000906:Antibodies; D011460:Prostaglandins F
La determinación radioinmunológica de las prostaglandinas F en plasma y en endometrio humano