Effectiveness of the nitrosoureas as a function of their lipid solubility in the chemotherapy of experimental rat brain tumors.
D000477:Alkylating Agents / Q000627:therapeutic use; D000818:Animals; D001932:Brain Neoplasms / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D006207:Half-Life; D008055:Lipids; D008297:Male; D009374:Neoplasms, Experimental / Q000188:drug therapy; D009607:Nitrosourea Compounds / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D051381:Rats; D011916:Rats, Inbred F344; D012044:Regression Analysis; D012509:Sarcoma / Q000188:drug therapy; D012995:Solubility; D013329:Structure-Activity Relationship
D000477:Alkylating Agents; D008055:Lipids; D009607:Nitrosourea Compounds