Effects of propranolol on gastric secretion in albino rats.
1 Effects of graded doses of propranolol have been studied on gastric secretion and gastric ulcers in pylorus-ligated rats.2 A dose-dependent action of propranolol was observed; small doses increased total volume, acid output and pepsin secretion along with an increase in the incidence of ulcers but high doses were inhibitory.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D005750:Gastric Juice / Q000187:drug effects / Q000378:metabolism*; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D008026:Ligation; D008297:Male; D011433:Propranolol / Q000494:pharmacology* / Q000627:therapeutic use; D011706:Pyloric Antrum / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000517:prevention & control
D011433:Propranolol