Alterations induced by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) in deoxyribonucleic acid synthesis in normal and tumorous tissues. Implications for optimal chemotherapy.
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001853:Bone Marrow / Q000378:metabolism; D002330:Carmustine / Q000494:pharmacology*; D004247:DNA / Q000032:analysis / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D004273:DNA, Neoplasm / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism; D007413:Intestinal Mucosa / Q000378:metabolism; D007939:Leukemia L1210 / Q000188:drug therapy / Q000378:metabolism; D051379:Mice; D008815:Mice, Inbred Strains; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D009607:Nitrosourea Compounds / Q000627:therapeutic use; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014316:Tritium
D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D009607:Nitrosourea Compounds; D014316:Tritium; D004247:DNA; D002330:Carmustine; D013936:Thymidine