title: [Theoretical and experimental principles and clinical aplications of the antiandrognes (author's transl)].
abstract: It is reported the accumulated experience over the last ten years on a synthetic gestegen with a powerful antiandrogenic action: the cyproterone acetate. The effects on androgen dependent processes like: structure and function of genital accesory glands, on skin and sebaceous glands, bone maturation and growth, libido and testicular function are reported, together with the clinical results obtained in the treatment of acne, hirsutism, sexual perversions and as male anticonceptive. The influence of cyproterone acetate on the androgen dependent embrionary processew of differentiation are also discussed as wll as the female anticonceptive action and its effects on other endocrine systems.
mesh_terms: D000726:Androgen Antagonists; D000818:Animals; D001846:Bone Development / Q000187:drug effects; D002645:Chickens; D006224:Cricetinae; D003534:Cyproterone / Q000009:adverse effects / Q000494:pharmacology*; D012734:Disorders of Sex Development / Q000139:chemically induced; D004285:Dogs; D004702:Endocrine Glands / Q000187:drug effects*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D005835:Genitalia / Q000187:drug effects*; D005849:Gerbillinae; D006801:Humans; D007989:Libido / Q000187:drug effects; D008297:Male; D011247:Pregnancy; D051381:Rats; D012098:Reproduction / Q000187:drug effects; D012627:Sebaceous Glands / Q000187:drug effects; D012867:Skin / Q000187:drug effects; D013739:Testosterone / Q000494:pharmacology
chemical_list: D000726:Androgen Antagonists; D013739:Testosterone; D003534:Cyproterone
vernacular_title: Fundamentos teórico-experimentales y aplicaciones clícas de los antiandrógenos