The increased rate of ethanol removal from blood of clofibrate-treated rats.
After ethanol injection similar metabolite changes were found in livers of clofibrate-treated and non-treated rats. The rate of ethanol removal from blood of clofibrate-treated rats was increased by 50%, but this was directly proportional to the increased liver size caused by clofibrate. No other difference needs to be postulated to explain the increased rate of ethanol removal from blood.
D000818:Animals; D002994:Clofibrate / Q000494:pharmacology*; D000431:Ethanol / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D009929:Organ Size; D051381:Rats; D013997:Time Factors
D000431:Ethanol; D002994:Clofibrate