Platelet function tests in uraemia  and under acetylsalicylic acid administration.
Procollagen-induced platelet aggregation, platelet retention (Hellem II), and platelet factor 3 availability (PF-3) were determinded in a group of healthy volunteers,acetylsalicylic acid (ASA) treated patients and in uraemic patients. ASA ingestion did not influence platelet retention and PF-3 availability. Uraemic patients had apronounced decrease in platelet aggregation and retention and PF-3 availability revealed inconsistent alterations. The relevance of the tests and the benefit of an ASA treatment for prophylaxis of thrombosis in Climino fistulae are discussed.
D001241:Aspirin / Q000494:pharmacology*; D001791:Blood Platelet Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D010973:Platelet Adhesiveness / Q000187:drug effects; D010974:Platelet Aggregation / Q000187:drug effects; D010977:Platelet Factor 3; D006435:Renal Dialysis; D013927:Thrombosis; D014511:Uremia / Q000150:complications*
D010977:Platelet Factor 3; D001241:Aspirin