Membrane glycopeptides from old and young human erythrocytes.
Glycopeptides were extracted by papain digestion from old and young human erythrocyte membranes and fractionated on DEAE-Sephadex A-25. Chemical characterization of the unfractionated samples and of the main peak eluted from the column indicates that glycoproteins of the erythrocyte membrane undergo significant decreases in sialic acid and galactosamine content with aging.
D002462:Cell Membrane / Q000032:analysis*; D002498:Centrifugation; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D002848:Chromatography, DEAE-Cellulose; D002849:Chromatography, Gas; D004912:Erythrocytes / Q000032:analysis*; D005688:Galactosamine / Q000378:metabolism; D006020:Glycopeptides / Q000097:blood*; D006801:Humans; D009438:Neuraminic Acids / Q000378:metabolism; D009996:Osmotic Fragility; D010206:Papain
D006020:Glycopeptides; D009438:Neuraminic Acids; D005688:Galactosamine; D010206:Papain