title: [Morphometry of endocrine organs. 2. Karyometry of dog and swine thyroid glands following administration of TURISYNCHRON and SUISYNCHRON].
abstract: Administration of TURISYNCHRON (metallibure) to dogs at 1 mg/kg/day for six months did not affect the histological structure of the thyroid, but the volume of nuclei of thyroid epithelial cells was reduced by one-third. In pigs given 100 mg/animal daily for 100 days, this nuclear contraction amounted to only 11%. Metallibure zinc complex (TURISYNCHRON-Z, SUISYNCHRON) given at 1 and 10 mg/kg/day for six months had a similar action on the thyroid.
mesh_terms: D000818:Animals; D002645:Chickens; D004285:Dogs; D004847:Epithelial Cells; D004848:Epithelium / Q000187:drug effects; D005260:Female; D007620:Karyometry; D009942:Organometallic Compounds / Q000494:pharmacology*; D013890:Thiourea / Q000031:analogs & derivatives* / Q000494:pharmacology; D013961:Thyroid Gland / Q000166:cytology / Q000187:drug effects*; D015032:Zinc / Q000494:pharmacology
chemical_list: D009942:Organometallic Compounds; D013890:Thiourea; D015032:Zinc
vernacular_title: Morphometrie an indokrinen Organen. II. Karyometrie an Schilddrüsen von Hunden und Schweinen nach Applikation von TURISYNCHRON und SUISYNCHRON