Prevention by methylprednisolone of the endothelial lesions in rabbits on a hypercholesterolic diet or submitted to immunologic injury.
Methylprednisolone injections inhibit the thickness increase of the Concanavalin A reactive coat at the endothelial cell surface both in rabbits on a hypercholesterolic diet or submitted to pig aortic homogenate injections.
D000818:Animals; D001011:Aorta / Q000166:cytology / Q000276:immunology; D001161:Arteriosclerosis / Q000473:pathology* / Q000517:prevention & control; D050260:Carbohydrate Metabolism; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D002791:Cholesterol, Dietary; D003208:Concanavalin A / Q000494:pharmacology*; D004036:Diet, Atherogenic; D005620:Freund's Adjuvant / Q000008:administration & dosage*; D008775:Methylprednisolone / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D011817:Rabbits; D013552:Swine; D014020:Tissue Extracts / Q000008:administration & dosage
D002791:Cholesterol, Dietary; D014020:Tissue Extracts; D003208:Concanavalin A; D005620:Freund's Adjuvant; D008775:Methylprednisolone