title: The effect of linkage on the mean value of inbreds derived from a random mating population.
abstract: An expression is derived which accounts for the effect of linkage on the mean value of diploid inbreds. The original population is taken to be in Hardy-Weinberg equilibrium. It is shown that linkage will accelerate inbreeding depression. The precise nature of the acceleration is worked out for some special cases.
mesh_terms: D000818:Animals; D004171:Diploidy; D008040:Genetic Linkage; D005838:Genotype; D006801:Humans; D007178:Inbreeding; D008954:Models, Biological