Distribution and metabolism of phenylalanine and tyrosine during tualraemia in the rat.
Tularaemia in rats causes a doubling of the serum phenylalanine/tyrosine ratio and a more than twofold increase in muscle phenylalanine which cannot be accounted for by decreased hepatic phenylalanine hydroxylase (EC 1.14.16.1) activity, but appear to result from a generalized movement of amino acids from muscle to liver during infection.
D000818:Animals; D008099:Liver / Q000201:enzymology; D008297:Male; D009132:Muscles / Q000032:analysis; D010649:Phenylalanine / Q000032:analysis / Q000097:blood / Q000378:metabolism*; D010651:Phenylalanine Hydroxylase / Q000378:metabolism; D051381:Rats; D014406:Tularemia / Q000378:metabolism*; D014443:Tyrosine / Q000097:blood / Q000378:metabolism*
D014443:Tyrosine; D010649:Phenylalanine; D010651:Phenylalanine Hydroxylase