[Calcitonin, calcium lactate-gluconate + potassium phosphate, calcium phosphate: changes induced in the biology of the patient with multiple fractures].
The effects of multiple injuries on the principle aspects of bone physiology are reviewed from the literature. In a clinical trial involving 14 patients with multiple fractures excluding cranial injuries, 5 were given porcine Calcitonin, two calcium gluconate-lactate with added potassium phosphate, and two calcium phosphate. Five patients acted as controls. The parameters under study were modified to varying degrees by the different substances. It was found that Calcitonin had no effect whatsoever on the healing of bone which remained virtually unaltered by the other compounds under trial.
D000469:Alkaline Phosphatase / Q000097:blood; D001842:Bone and Bones / Q000378:metabolism*; D002116:Calcitonin / Q000627:therapeutic use*; D002118:Calcium / Q000378:metabolism / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000627:therapeutic use*; D004341:Drug Evaluation; D050723:Fractures, Bone / Q000188:drug therapy* / Q000378:metabolism; D005942:Gluconates / Q000627:therapeutic use; D006801:Humans; D006909:Hydroxyproline / Q000652:urine; D007773:Lactates / Q000627:therapeutic use; D008274:Magnesium / Q000097:blood; D010024:Osteoporosis; D010710:Phosphates / Q000627:therapeutic use; D010758:Phosphorus / Q000378:metabolism; D011188:Potassium / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects*
D002130:Calcium Phosphates; D005942:Gluconates; D007773:Lactates; D010710:Phosphates; D010758:Phosphorus; D002116:Calcitonin; D000469:Alkaline Phosphatase; D008274:Magnesium; D006909:Hydroxyproline; D011188:Potassium; D002118:Calcium
Calcitonina, lattato-gluconato di Ca + fosfato di K, fosfato di Ca: modificazioni indotte sulla biologia del polifratturato