Changing time perception with antidepressant drug therapy.
A pilot study on the time sense of ten depressed patients was performed before and during, as well as after, antidepressant therapy with tricyclic compounds. Short time spans were measured by two methods, giving then two different tasks. Measurements were performed in the morning as well as evening hours, in order to take into account diuranl variations. Accuracy of time estimation was considerably deviant. All except one patient overestimated time. With improvement, time sense also improved. Errors were still greater in the morning. The value of the results are discussed.
D000639:Amitriptyline / Q000494:pharmacology* / Q000627:therapeutic use; D003863:Depression / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010865:Pilot Projects; D013998:Time Perception / Q000187:drug effects*
D000639:Amitriptyline