[Several clinical-x-ray manifestations of myeloma disease in Bulgaria].
Two hundred patients with myeloma disease have been reported in Bulgarian medical literature for the period 1943-1973. The males are 62.3 per cent and the females--37.7 per cent. Out of all the cases 91.2 per cent are at the age of 40 and 48 per cent of the patients--between 51--60. The following incidence rate of the investigated syndromes and symptoms was established: osseous--96 per cent, asthenic-dynamic--93.2 per cent, consumptive--74,6 per cent, neurologic--57.4 per cent, febrility--53 per cent, hepatomegalia--50 per cent, splenomegaly--24.3 per cent, lymphoadenomegalia--23.5, per cent, hemorrhagic--37.1 per cent, skin manifestations--20.7 per cent, spontaneous fractures--42.7 per cent, osseous tumors--25 per cent, hypercalcemia--56.1 per cent, broachitis and bronchopneumonia--50.7 per cent of the patients. The distribution according to the X-ray criteria reveals: osteolytic form--81,4 per cent; diffuse-porotic--9.3 per cent and osteonegative--9.3 per cent. The diagnosis was made within 1 1/2 years after the appearance of the first manifestations. The average life span is about 2 years (2 1/2 months to 5 1/2 years). A difference in the prognosis of beta1-,beta2- and gamma-myelomas was no testablished.
D000328:Adult; D001247:Asthenia; D002031:Bulgaria; D005260:Female; D005334:Fever; D005598:Fractures, Spontaneous / Q000209:etiology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D009461:Neurologic Manifestations; D012877:Skin Manifestations; D013577:Syndrome
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