An extreme diminution in the strong affinity of 2-amino-4-hydroxy-6-formylpteridine for xanthine oxidase by reduction of a 7, 8-double bond or a formyl group at position 6 of its pyrazine ring.
D000588:Amines / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D007700:Kinetics; D008433:Mathematics; D008892:Milk / Q000201:enzymology*; D008956:Models, Chemical; D010084:Oxidation-Reduction; D011048:Polarography; D011621:Pteridines / Q000378:metabolism* / Q000494:pharmacology; D011719:Pyrazines / Q000378:metabolism / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D014970:Xanthines
D000588:Amines; D011621:Pteridines; D011719:Pyrazines; D014970:Xanthines; D014969:Xanthine Oxidase