[Leukemia of a still-born child (author's transl)].
A case of a stemcell-leukemia of a mature male macerated still-born child is described. The mother, a 20-year-old healthy bipara, a milker-maid by profession, had a normal hemogram. There was no evidence of blood group incompatibility. The autopsy of the fetus showed an excessive tumorous enlargement of the pancreas caused by the leukemic infiltration (Fig. 1). The microscopic examination of the placenta showed leukemic cells in the fetal blood vessels and the villous stroma (Fig. 2). In 1966 Werner compiled from literature 28 cases of true connatal leukemia and added a case of his own. From the newer accessible literature we collected further 19 reports (Table). In 7 of the 49 cases the connatal leukemia appeared together with Down's syndrom.
D000208:Acute Disease; D001344:Autopsy; D005260:Female; D005313:Fetal Death / Q000150:complications* / Q000473:pathology; D006412:Hematopoietic Stem Cells; D006801:Humans; D007231:Infant, Newborn; D007938:Leukemia / Q000150:complications* / Q000151:congenital / Q000473:pathology; D008297:Male; D010190:Pancreatic Neoplasms / Q000473:pathology; D010920:Placenta / Q000473:pathology; D011247:Pregnancy
Leukose bei einem Totgeborenen