Delayed removal of N-terminal methionine from nascent globin chains in sickle-cell anemia reticulocytes.
D000755:Anemia, Sickle Cell / Q000097:blood*; D000818:Animals; D002845:Chromatography; D006451:Hemoglobin, Sickle / Q000096:biosynthesis; D006454:Hemoglobins / Q000096:biosynthesis*; D006455:Hemoglobins, Abnormal / Q000096:biosynthesis*; D006801:Humans; D066298:In Vitro Techniques; D008239:Lysine / Q000378:metabolism; D008715:Methionine / Q000378:metabolism*; D010452:Peptide Biosynthesis; D010441:Peptide Chain Elongation, Translational; D010455:Peptides / Q000302:isolation & purification; D011817:Rabbits; D012156:Reticulocytes / Q000378:metabolism*; D013460:Sulfur Isotopes; D014316:Tritium; D014633:Valine / Q000378:metabolism
D006451:Hemoglobin, Sickle; D006454:Hemoglobins; D006455:Hemoglobins, Abnormal; D010455:Peptides; D013460:Sulfur Isotopes; D014316:Tritium; D008715:Methionine; D014633:Valine; D008239:Lysine