Calcium-like action of phenethylbiguanide and related compounds: inhibition of pyruvate kinase.
D000818:Animals; D001645:Biguanides; D001665:Binding Sites; D002118:Calcium; D002127:Calcium Isotopes; D003402:Creatine Kinase / Q000037:antagonists & inhibitors; D004789:Enzyme Activation; D006593:Hexokinase / Q000037:antagonists & inhibitors; D007700:Kinetics; D008094:Lithium; D008345:Manganese; D009132:Muscles / Q000201:enzymology*; D010629:Phenformin; D010733:Phosphoglucomutase / Q000037:antagonists & inhibitors; D010735:Phosphoglycerate Kinase / Q000037:antagonists & inhibitors; D011485:Protein Binding; D011770:Pyruvate Kinase / Q000037:antagonists & inhibitors*; D000644:Quaternary Ammonium Compounds; D011817:Rabbits; D011868:Radioisotopes; D013329:Structure-Activity Relationship; D014316:Tritium
D001645:Biguanides; D002127:Calcium Isotopes; D000644:Quaternary Ammonium Compounds; D011868:Radioisotopes; D014316:Tritium; D008345:Manganese; D008094:Lithium; D010629:Phenformin; D006593:Hexokinase; D011770:Pyruvate Kinase; D010735:Phosphoglycerate Kinase; D003402:Creatine Kinase; D010733:Phosphoglucomutase; D002118:Calcium