Development of acute leukaemia in Waldenstrom's macroglobulinaemia after prolonged treatment with chlorambucil.
D000368:Aged; D002699:Chlorambucil / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000139:chemically induced*; D011694:Purpura, Hyperglobulinemic / Q000188:drug therapy*; D013997:Time Factors
D002699:Chlorambucil