Aryl hydrocarbon hydroxylase and polycyclic hydrocarbon tumorigenesis: effect of the enzyme inhibitor 7,8-benzoflavone on tumorigenesis and macromolecule binding.
D000818:Animals; D001551:Benz(a)Anthracenes; D001580:Benzopyrenes; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D004273:DNA, Neoplasm / Q000378:metabolism; D003864:Depression, Chemical; D004790:Enzyme Induction / Q000187:drug effects; D005419:Flavonoids / Q000494:pharmacology*; D006838:Hydrocarbons; D046911:Macromolecular Substances / Q000378:metabolism*; D008297:Male; D051379:Mice; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D009363:Neoplasm Proteins / Q000378:metabolism; D009374:Neoplasms, Experimental / Q000139:chemically induced; D011485:Protein Binding / Q000187:drug effects*; D012334:RNA, Neoplasm / Q000378:metabolism; D012867:Skin / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D014316:Tritium
D001551:Benz(a)Anthracenes; D001580:Benzopyrenes; D004273:DNA, Neoplasm; D005419:Flavonoids; D006838:Hydrocarbons; D046911:Macromolecular Substances; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm; D014316:Tritium; D006899:Mixed Function Oxygenases