title: Chromosome replication and cell division in Escherichia coli at various temperatures of growth.
abstract: The effect of temperature on the growth rate and the pattern of chromosome replication during the division cycle of Escherichia coli B/r growing in various media was investigated. The time between divisions, the time for a round of replication (C), and the time between completion of a round and cell division (D) were threefold longer at 21 C than at 37 C. At all temperatures and in all media, D equalled one-half C, suggesting that a common mechanism controls chromosome replication and the progression of the cell toward division after completion of a round of replication.
mesh_terms: D000085:Acetates / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D002247:Carbon Isotopes; D002455:Cell Division; D002876:Chromosomes, Bacterial; D003470:Culture Media; D004261:DNA Replication; D004269:DNA, Bacterial / Q000096:biosynthesis; D004926:Escherichia coli / Q000254:growth & development* / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D013053:Spectrophotometry; D013386:Succinates / Q000378:metabolism; D013696:Temperature; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014316:Tritium
chemical_list: D000085:Acetates; D000596:Amino Acids; D002247:Carbon Isotopes; D003470:Culture Media; D004269:DNA, Bacterial; D013386:Succinates; D014316:Tritium; D005947:Glucose; D013936:Thymidine