title: [Rheumatic manifestations of primary hypogammaglobulinemia in the adult].
abstract: With reference to 27 cases reported in the literature (of which 1 was personal) of primary hypogammaglobulinaemia in adults (PHGGA) with rheumatic manifestations, and following a statistical study, the authors think that the rheumatic manifestations that precede, accompany, or follow primary hypogammaglobulinaemia in adults are not coincidental. These manifestations occur in 10 percent of patients. The clinical and radiological pictures, and the associated infections and immunological disorders form a particular clinical entity and lead to therapeutic difficultires. In this connexion, the authors mention in particular pathogenic problems related to hypogammaglobulinaemia in adults and the rheumatic manifestations.
mesh_terms: D000293:Adolescent; D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D000743:Anemia, Hemolytic / Q000150:complications; D001168:Arthritis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D001706:Biopsy; D002648:Child; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012157:Mononuclear Phagocyte System / Q000276:immunology; D011859:Radiography; D012216:Rheumatic Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013583:Synovial Membrane / Q000473:pathology; D013945:Thymoma / Q000150:complications
chemical_list: D007136:Immunoglobulins
vernacular_title: Les manifestations rhumatismales de l'hypogammaglobulinémie primaire de l'adulte