Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism).
Amphotericin B potentiates the antifungal effects of 5-fluorocytosine and rifampicin, probably by increasing the penetration of these agents through the fungal cytoplasmic membrane.
D000178:Acrylamides; D000666:Amphotericin B / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D002247:Carbon Isotopes; D002463:Cell Membrane Permeability / Q000187:drug effects; D003455:Cryptococcus neoformans / Q000187:drug effects; D003596:Cytosine / Q000494:pharmacology*; D004338:Drug Combinations; D004357:Drug Synergism; D004586:Electrophoresis; D005461:Fluorine; D008826:Microbial Sensitivity Tests; D012313:RNA / Q000096:biosynthesis; D012293:Rifampin / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D014316:Tritium; D014498:Uracil
D000178:Acrylamides; D000935:Antifungal Agents; D002247:Carbon Isotopes; D004338:Drug Combinations; D014316:Tritium; D005461:Fluorine; D014498:Uracil; D012313:RNA; D000666:Amphotericin B; D003596:Cytosine; D012293:Rifampin