Studies of peripheral blood T-and B-lymphocytes in acute infections.
E-binding (T) and immunoglobulin-bearing (B) lymphocytes were determined in 22 patients with acute infections. The percentage of T-cells was depressed in most patients in the early stages of disease, whereas the B-cell proportion was usually elevated compared with convalescence and controls. The B-cell increase occurred earlier in a small group of viral or mycoplasmal infections than in bacterial infections. Four patients with unusually high numbers of B-cells had no corresponding increase in EAC3-binding lymphocytes. Almost all lymphocytes from pleural effusion in a patient with tuberculosis were found to be T-cells.
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D001424:Bacterial Infections / Q000276:immunology; D001665:Binding Sites; D002469:Cell Separation; D003165:Complement System Proteins; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006801:Humans; D007104:Immune Adherence Reaction; D007106:Immune Sera; D007136:Immunoglobulins; D007239:Infections / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000276:immunology; D012756:Sheep / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D014777:Virus Diseases / Q000276:immunology
D007106:Immune Sera; D007136:Immunoglobulins; D003165:Complement System Proteins