title: High-dose methotrexate with citrovorum factor rescue and adriamycin in childhood osteogenic sarcoma.
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D002648:Child; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005069:Evaluation Studies as Topic; D005260:Female; D006413:Hematopoietic System / Q000187:drug effects; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D009092:Mucous Membrane / Q000187:drug effects; D009325:Nausea / Q000139:chemically induced; D009362:Neoplasm Metastasis; D012516:Osteosarcoma / Q000188:drug therapy* / Q000201:enzymology
chemical_list: D004317:Doxorubicin; D001219:Aspartate Aminotransferases; D000469:Alkaline Phosphatase; D002955:Leucovorin; D008727:Methotrexate