title: Improved therapeutic index of methotrexate with "leucovorin rescue".
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D004357:Drug Synergism; D005260:Female; D006257:Head; D006258:Head and Neck Neoplasms / Q000188:drug therapy*; D006801:Humans; D007275:Injections, Intravenous; D002955:Leucovorin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use*; D008875:Middle Aged
chemical_list: D002955:Leucovorin; D008727:Methotrexate