Quinazoline antifolates as inhibitors of growth, dihydrofolate reductase, and thymidylate synthetase of mouse neuroblastoma cells in culture.
D000818:Animals; D002478:Cells, Cultured; D002854:Chromatography, Paper; D005493:Folic Acid Antagonists / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D006128:Growth / Q000187:drug effects*; D007700:Kinetics; D002955:Leucovorin / Q000494:pharmacology; D008780:Methyltransferases / Q000037:antagonists & inhibitors*; D051379:Mice; D009374:Neoplasms, Experimental / Q000201:enzymology; D009447:Neuroblastoma / Q000201:enzymology*; D011799:Quinazolines / Q000037:antagonists & inhibitors / Q000138:chemical synthesis / Q000494:pharmacology*; D013936:Thymidine / Q000494:pharmacology; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors*
D005493:Folic Acid Antagonists; D011799:Quinazolines; D008780:Methyltransferases; D013940:Thymidylate Synthase; D002955:Leucovorin; D013936:Thymidine