Impairment of host cell ribonucleic acid polymerase II after infection with frog virus 3.
Evidence is presented that, in frog virus 3-infected BHK cells, inhibition of ribonucleic acid (RNA) synthesis is paralleled by a decreased activity of host cell RNA polymerase II, while the template ability of host cell nuclei and chromatin is unaffected.
D000818:Animals; D001001:Anura; D002460:Cell Line / Q000201:enzymology / Q000378:metabolism; D002467:Cell Nucleus; D002843:Chromatin; D002848:Chromatography, DEAE-Cellulose; D006224:Cricetinae; D003588:Cytopathogenic Effect, Viral; D004247:DNA / Q000378:metabolism; D004267:DNA Viruses / Q000254:growth & development*; D004926:Escherichia coli / Q000201:enzymology; D007668:Kidney; D009183:Mycotoxins / Q000494:pharmacology; D012313:RNA / Q000096:biosynthesis; D012316:RNA Nucleotidyltransferases / Q000378:metabolism*; D013698:Templates, Genetic; D014465:Ultrasonics; D014732:Vibration
D002843:Chromatin; D009183:Mycotoxins; D012313:RNA; D004247:DNA; D012316:RNA Nucleotidyltransferases