Effect of carrier modification on the cellular and serologic responses of the rat to the TNP hapten. I. Dependence of the immunogenicity of the antigen upon processing by macrophages, as well as upon the distribution and retention of the antigen.
D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells; D000941:Antigens / Q000032:analysis; D001345:Autoradiography; D002352:Carrier Proteins; D002725:Chloroform / Q000494:pharmacology; D005260:Female; D006241:Haptens; D006386:Hemagglutination Tests; D006433:Hemocyanins; D006462:Hemolytic Plaque Technique; D007111:Immunity, Cellular; D007116:Immunization, Passive; D007117:Immunization, Secondary; D007074:Immunoglobulin G / Q000032:analysis; D007456:Iodine Isotopes; D008099:Liver / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D009596:Nitrophenols; D010587:Phagocytosis; D051381:Rats; D013154:Spleen / Q000276:immunology
D000941:Antigens; D002352:Carrier Proteins; D006241:Haptens; D007074:Immunoglobulin G; D007456:Iodine Isotopes; D009596:Nitrophenols; D002725:Chloroform; D006433:Hemocyanins