Use of ferritin-labelled antibodies for differentiating Leishmania species and other Trypanosomatidae.
A new immunomorphological test for differentiating Leishmania species, based on electron-microscopic revelation of the localization of their specific antigens, is described. The diagnostic value of treating the promastigotes of Leishmania and other Trypanosomatidae with ferritin-labelled antibodies was determined in cross experiments. The immunoferritin test reveals both the serogroup of a given species of Leishmania and specific antigenic differences between different species. However, it fails to differentiate different strains of a given species of Leishmania, which attests to its species-specificity.
D000818:Animals; D000906:Antibodies; D006224:Cricetinae; D005293:Ferritins; D007891:Leishmania / Q000145:classification* / Q000166:cytology / Q000276:immunology; D008854:Microscopy, Electron; D014345:Trypanosoma / Q000145:classification* / Q000166:cytology / Q000276:immunology
D000906:Antibodies; D005293:Ferritins