Prevention of endemic goitre with iodized salt.
The paper describes a study, carried out over 16 years, of the use of iodized salt for the control of endemic goitre in a valley of the Himalayan foothills. From 1956, salt was fortified with either potassium iodide or potassium iodate to provide an estimated daily intake of 200 mug per head. There was a progressive and significant decline in goitre prevalence, together with a return of the pattern of iodine metabolism to within normal limits. It is concluded that endemic goitre can be successfully controlled by iodization of domestic salt.
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005527:Food, Fortified; D006043:Goiter, Endemic / Q000517:prevention & control*; D006801:Humans; D007194:India; D007223:Infant; D007452:Iodates / Q000627:therapeutic use; D007455:Iodine / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D011188:Potassium / Q000627:therapeutic use; D011193:Potassium Iodide / Q000627:therapeutic use; D012965:Sodium Chloride
D007452:Iodates; D011193:Potassium Iodide; D012965:Sodium Chloride; D007455:Iodine; D011188:Potassium