Laboratory and clinical investigation of the 1974 influenza epidemic in Nigeria.
Altogether 13 strains of virus were isolated during the 1974 influenza epidemic in Nigeria. These A/Nigeria/1/74 strains were shown by haemagglutination-inhibition tests to be closely related to the A/Port Chalmers/1/73 virus. Antibody to the epidemic strains developed rapidly in the population and 80-95% of all age groups tested possessed high antibody levels; of 145 paired sera tested, 133 (92%) showed sero-conversion to A/Nigeria/1/74 virus.
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009980:Influenza A virus / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology / Q000276:immunology*; D009549:Nigeria; D009975:Orthomyxoviridae / Q000276:immunology*; D012703:Serotyping
D000914:Antibodies, Viral