Synthesis of some N-carboxylic acid derivatives of 3-phenoxypyrrolidines, 4-phenoxypiperidines, and 3-phenoxynortropanes with muscle relaxant and anticonvulsant activities.
D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects; D002415:Cats; D002818:Cordotomy; D004305:Dose-Response Relationship, Drug; D004558:Electric Stimulation; D004597:Electroshock; D005260:Female; D051379:Mice; D008813:Mice, Inbred ICR; D009043:Motor Activity / Q000187:drug effects; D009119:Muscle Contraction / Q000187:drug effects; D009125:Muscle Relaxants, Central / Q000138:chemical synthesis* / Q000494:pharmacology; D009469:Neuromuscular Junction / Q000187:drug effects; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D010647:Phenyl Ethers / Q000138:chemical synthesis; D010880:Piperidines / Q000138:chemical synthesis*; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000494:pharmacology; D012023:Reflex, Monosynaptic / Q000187:drug effects; D012640:Seizures / Q000517:prevention & control; D013126:Spinal Nerve Roots / Q000502:physiology; D014326:Tropanes / Q000138:chemical synthesis* / Q000494:pharmacology
D000927:Anticonvulsants; D009125:Muscle Relaxants, Central; D010647:Phenyl Ethers; D010880:Piperidines; D011759:Pyrrolidines; D014326:Tropanes; D010433:Pentylenetetrazole