Genetic correlation of a mouse light chain variable region marker with a thymocyte surface antigen.
The inbred and congenic strain distribution of the I(H)-peptide marker in the variable region of mouse immunoglobulin light chains has been compared with other known genetic markers. A positive correlation was noted between the I(H)-peptide marker and expression of the Ly-3.1 thymocyte cell surface antigen. This suggests that the locus responsible for I(H)-peptide expression is genetically linked to the Ly-2 and Ly-3 loci in linkage group XI on chromsome 6 of the mouse.
D000818:Animals; D000941:Antigens; D002462:Cell Membrane / Q000276:immunology*; D002874:Chromosome Mapping; D005796:Genes; D008040:Genetic Linkage; D007128:Immunoglobulin Fragments; D051379:Mice; D008815:Mice, Inbred Strains / Q000276:immunology; D010455:Peptides / Q000032:analysis; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D007128:Immunoglobulin Fragments; D010455:Peptides