Influence of temperature on the biosynthesis of iron transport compounds by Salmonella typhimurium.
The biosynthesis of phenolate iron transport compounds by Salmonella typhimurium Tm-1 is temperature-sensitive. As the temperature of incubation is raised from 31.0 to 36.9 C, the organism excretes less iron transport compound into the medium. The organism in unable to grow at 40.3 C on a 1% succinatesalts medium unless supplemented with such iron transport compounds. The iron requirement for maximum cell yields on this medium is 0.10 mug/ml. The biosynthesis of phenolate iron transport compounds is suppressed at iron concentrations greater than 3.0 mug/ml.
D001565:Benzoates / Q000096:biosynthesis / Q000494:pharmacology; D007501:Iron / Q000494:pharmacology; D007502:Iron Chelating Agents / Q000096:biosynthesis* / Q000494:pharmacology; D010636:Phenols / Q000096:biosynthesis* / Q000494:pharmacology; D012486:Salmonella typhimurium / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D012694:Serine / Q000096:biosynthesis / Q000494:pharmacology; D013696:Temperature
D001565:Benzoates; D007502:Iron Chelating Agents; D010636:Phenols; D012694:Serine; D007501:Iron