title: 5-(1-Adamantyl) pyrimidines as inhibitors of folate metabolism.
mesh_terms: D000818:Animals; D001952:Bridged-Ring Compounds / Q000494:pharmacology; D002478:Cells, Cultured; D003516:Cycloparaffins / Q000494:pharmacology; D003864:Depression, Chemical; D004926:Escherichia coli / Q000201:enzymology; D005492:Folic Acid / Q000378:metabolism*; D005493:Folic Acid Antagonists; D066298:In Vitro Techniques; D007700:Kinetics; D008727:Methotrexate / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology*; D012510:Sarcoma 180 / Q000201:enzymology; D013329:Structure-Activity Relationship
chemical_list: D001952:Bridged-Ring Compounds; D003516:Cycloparaffins; D005493:Folic Acid Antagonists; D011743:Pyrimidines; D005492:Folic Acid; D008727:Methotrexate