title: Poliomyelitis in the Netherlands 1958-69: the influence of a vaccination programme with inactivated poliovaccine.
abstract: The Netherlands is one of the few countries where poliomyelitis vaccination is practised with inactivated vaccine. Vaccinations started in 1957 and since 1962 have been carried out with a diphtheria-tetanus-pertussis-poliomyelitis vaccine according to a fixed schedule. The overall acceptance rate has been over 90%.Since 1957 the poliomyelitis morbidity has decreased by more than 99% in fully vaccinated persons and by 60-80% among nonvaccinated persons. The latter reduction probably resulted from a decrease in the amount of virus circulating after the vaccination campaign had started. The rather unequal distribution of acceptance rates allowed for a more detailed examination, which showed a relation between acceptance rates and morbidity figures. The morbidity pattern is now characterized by a few local outbreaks among nonvaccinated subjects in areas with low vaccination rates, and by the virtual disappearance of the disease in the rest of the country.
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009426:Netherlands; D011051:Poliomyelitis / Q000453:epidemiology / Q000517:prevention & control*; D011054:Poliovirus Vaccine, Inactivated; D014611:Vaccination
chemical_list: D011054:Poliovirus Vaccine, Inactivated