A common tumour specific antigen. II. Further characterization of the whole antigen and of a cross-reacting antigen of normal tissues.
Experimental evidence supporting the postulated analogy between myelin basic protein and a previously described common tumour specific antigen is summarized under antigenic cross-reactivity, subcellular localization, molecular size, basicity and proteolipid nature. A third protein antigen, present in all tissues, also shows strong similarities in all these respects.
D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm / Q000032:analysis*; D001943:Breast Neoplasms / Q000276:immunology; D002852:Chromatography, Ion Exchange; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007945:Leukemia, Lymphoid / Q000276:immunology; D015470:Leukemia, Myeloid, Acute / Q000276:immunology; D007962:Leukocytes / Q000276:immunology; D008055:Lipids / Q000032:analysis; D008970:Molecular Weight; D009186:Myelin Sheath / Q000276:immunology; D009419:Nerve Tissue Proteins / Q000032:analysis; D013154:Spleen / Q000276:immunology; D013347:Subcellular Fractions / Q000276:immunology; D002583:Uterine Cervical Neoplasms / Q000276:immunology; D014625:Vaginal Neoplasms / Q000276:immunology
D000951:Antigens, Neoplasm; D008055:Lipids; D009419:Nerve Tissue Proteins