title: Prophylactic central nervous system therapy with cranial irradiation and intrathecal methotrexate in acute lymphoblastic leukemia of childhood.
mesh_terms: D000293:Adolescent; D001215:Asparaginase / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D007278:Injections, Spinal; D007945:Leukemia, Lymphoid / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008580:Meningism / Q000517:prevention & control*; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use; D011867:Radioisotope Teletherapy; D011878:Radiotherapy / Q000009:adverse effects; D011879:Radiotherapy Dosage; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D003037:Cobalt Radioisotopes; D014750:Vincristine; D001215:Asparaginase; D011241:Prednisone; D008727:Methotrexate