title: Isolation and some properties of the genes coding for histone proteins.
abstract: The DNA coding for histone proteins, together with the intervening spacer DNA, has been isolated from the sea urchin, Psammechinus miliaris, by repeated centrifugation on CsCl-asctinomycin gradients. The biophysical data show that a major portion of the spacer is 37% G+C and very divergent in sequence, while the DNA segments coding for histone proteins are high in G+C and have diverged to a lesser extent within the species.
mesh_terms: D000818:Animals; D001483:Base Sequence; D002499:Centrifugation, Density Gradient; D004247:DNA / Q000302:isolation & purification*; D005796:Genes; D005815:Genetic Code; D006657:Histones / Q000096:biosynthesis*; D006358:Hot Temperature; D009693:Nucleic Acid Hybridization; D012617:Sea Urchins
chemical_list: D006657:Histones; D004247:DNA