Isolation and some properties of the genes coding for histone proteins.
The DNA coding for histone proteins, together with the intervening spacer DNA, has been isolated from the sea urchin, Psammechinus miliaris, by repeated centrifugation on CsCl-asctinomycin gradients. The biophysical data show that a major portion of the spacer is 37% G+C and very divergent in sequence, while the DNA segments coding for histone proteins are high in G+C and have diverged to a lesser extent within the species.
D000818:Animals; D001483:Base Sequence; D002499:Centrifugation, Density Gradient; D004247:DNA / Q000302:isolation & purification*; D005796:Genes; D005815:Genetic Code; D006657:Histones / Q000096:biosynthesis*; D006358:Hot Temperature; D009693:Nucleic Acid Hybridization; D012617:Sea Urchins
D006657:Histones; D004247:DNA