Synthesis of purine nucleotides in human and leukemic cells. Interaction of 6-mercaptopurine and allopurinol.
D000225:Adenine; D000493:Allopurinol / Q000494:pharmacology*; D001853:Bone Marrow / Q000187:drug effects / Q000201:enzymology; D001854:Bone Marrow Cells; D002250:Carbon Radioisotopes; D002474:Cell-Free System; D002854:Chromatography, Paper; D005561:Formates; D006150:Guanine Nucleotides; D006801:Humans; D007042:Hypoxanthines; D007700:Kinetics; D002955:Leucovorin; D007938:Leukemia / Q000201:enzymology*; D015470:Leukemia, Myeloid, Acute / Q000201:enzymology; D007962:Leukocytes / Q000187:drug effects / Q000201:enzymology; D008025:Ligases / Q000378:metabolism*; D015122:Mercaptopurine / Q000494:pharmacology*; D010428:Pentosephosphates; D010430:Pentosyltransferases / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D013763:Tetrahydrofolates
D002250:Carbon Radioisotopes; D005561:Formates; D006150:Guanine Nucleotides; D007042:Hypoxanthines; D010428:Pentosephosphates; D013763:Tetrahydrofolates; D000493:Allopurinol; D015122:Mercaptopurine; D010430:Pentosyltransferases; D008025:Ligases; D000225:Adenine; D002955:Leucovorin