Clearence of antibiotics from the intestines after termination of antibiotic decontamination.
The clearance of neomycin and kanamycin from the intestines after stopping oral supply has been determined in mice. Both antibiotics, although given in different doses, were excreted in essentially the same way; the clearance being a little faster than logarithmically in both cases. The importance of this observation with regard to isolation and the moment of reconventionalization is discussed.
D000818:Animals; D001414:Bacitracin / Q000378:metabolism; D004396:Coloring Agents; D005243:Feces / Q000032:analysis; D005260:Female; D005856:Germ-Free Life; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000378:metabolism*; D007421:Intestine, Small; D007422:Intestines / Q000382:microbiology; D007612:Kanamycin / Q000378:metabolism*; D051379:Mice; D009355:Neomycin / Q000378:metabolism*; D010528:Peristalsis; D013997:Time Factors
D004396:Coloring Agents; D001414:Bacitracin; D007612:Kanamycin; D009355:Neomycin