title: The 1970 yellow fever epidemic in Okwoga District, Benue Plateau State, Nigeria. 3. Serological responses in persons with and without pre-existing heterologous group B immunity.
abstract: Serological studies of persons infected with yellow fever (YF) during the 1970 epidemic in Okwoga District, Nigeria, indicated that epidemic YF occurred despite a high prevalence of pre-existing group B arbovirus immunity, which increased with age. The viruses involved were primarily dengue, Zika, and Wesselsbron. Patterns of responses of haemagglutination-inhibiting, complement-fixing, and neutralizing antibodies in primary YF and in superinfections are defined in this paper.
mesh_terms: D000293:Adolescent; D000328:Adult; D000910:Antibodies, Heterophile / Q000032:analysis*; D000914:Antibodies, Viral / Q000032:analysis; D001103:Arboviruses / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D003168:Complement Fixation Tests; D004196:Disease Outbreaks; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007110:Immunity, Active; D007223:Infant; D009500:Neutralization Tests; D009549:Nigeria; D015004:Yellow Fever / Q000453:epidemiology / Q000276:immunology*; D015005:Yellow fever virus / Q000276:immunology
chemical_list: D000910:Antibodies, Heterophile; D000914:Antibodies, Viral