title: The pi-histidine factor of Salmonella typhimurium: a demonstration that pi-histidine factor integrates into the chromosome.
abstract: The Salmonella typhimurium pi-histidine episome was identified by Ames et al. (2) in an unstable partial revertant of a deletion mutation-containing strain, hisG203. HisG203 lacks the histidine operator, promoter, and part of the first structural gene. In this paper, we study some properties of pi factor and demonstrate a low frequency of pi integration into the chromosome at or near the histidine region.
mesh_terms: D000166:Acridines / Q000494:pharmacology; D000429:Alcohol Oxidoreductases / Q000378:metabolism; D000605:Amino Alcohols; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial / Q000378:metabolism*; D003227:Conjugation, Genetic; D003470:Culture Media; D004171:Diploidy; D005796:Genes; D006639:Histidine / Q000378:metabolism*; D006836:Hydro-Lyases / Q000378:metabolism; D008025:Ligases / Q000378:metabolism; D009153:Mutagens; D009154:Mutation; D009604:Nitrosoguanidines; D009876:Operon; D010406:Penicillins; D010734:Phosphogluconate Dehydrogenase / Q000378:metabolism; D011995:Recombination, Genetic; D012265:Ribonucleotides; D012486:Salmonella typhimurium / Q000187:drug effects / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*; D014161:Transduction, Genetic
chemical_list: D000166:Acridines; D000605:Amino Alcohols; D003470:Culture Media; D009153:Mutagens; D009604:Nitrosoguanidines; D010406:Penicillins; D012265:Ribonucleotides; D006639:Histidine; D000429:Alcohol Oxidoreductases; D010734:Phosphogluconate Dehydrogenase; D006836:Hydro-Lyases; D008025:Ligases