Inhibition of dopa decarboxylation by RO4-4602, MK 485 and MK 486 in human liver homogenates.
D006916:5-Hydroxytryptophan / Q000378:metabolism; D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D001593:Benzyl Compounds / Q000494:pharmacology; D001665:Binding Sites; D002247:Carbon Isotopes; D003300:Copper / Q000494:pharmacology; D003653:Decarboxylation; D003864:Depression, Chemical; D004295:Dihydroxyphenylalanine / Q000378:metabolism*; D006801:Humans; D006834:Hydrazines / Q000494:pharmacology*; D066298:In Vitro Techniques; D007700:Kinetics; D008099:Liver / Q000201:enzymology / Q000378:metabolism*; D008750:Methyldopa / Q000494:pharmacology*; D012694:Serine / Q000494:pharmacology*
D065105:Aromatic Amino Acid Decarboxylase Inhibitors; D001593:Benzyl Compounds; D002247:Carbon Isotopes; D006834:Hydrazines; D012694:Serine; D008750:Methyldopa; D004295:Dihydroxyphenylalanine; D003300:Copper; D006916:5-Hydroxytryptophan