Sequences present in both human leukemic cell nuclear DNA and Rauscher leukemia virus.
DNA synthesized by particulate fractions from human leukemic white blood cells has been subfractionated by hybridization to Rauscher leukemia virus 70S RNA followed by hydroxylapatite chromatography. The Rauscher-leukemia-virus-specific DNA fraction is shown to be complementary only to sequences present in the nuclear DNA of Balb/c mouse spleens infected by this virus and the nuclear DNA from human leukemic white blood cells, and not to sequences present in the nuclear DNA of normal Balb/c mouse spleens or the nuclear DNA of normal human white blood cells.
D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D002499:Centrifugation, Density Gradient; D002845:Chromatography; D004273:DNA, Neoplasm / Q000378:metabolism*; D004279:DNA, Viral / Q000378:metabolism*; D005816:Genetic Complementation Test; D006801:Humans; D007938:Leukemia / Q000097:blood; D015470:Leukemia, Myeloid, Acute / Q000378:metabolism*; D008214:Lymphocytes / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D009693:Nucleic Acid Hybridization; D011925:Rauscher Virus / Q000378:metabolism*; D013154:Spleen / Q000378:metabolism
D004273:DNA, Neoplasm; D004279:DNA, Viral