title: Polynucleotide phosphorylase has a role in growth of Escherichia coli.
abstract: Mutants having low levels of polynucleotide phosphorylase activity grow poorly at 45 C. All revertants isolated for their ability to grow better at that temperature also regained higher levels of polynucleotide phosphorylase and the ability to be induced for tryptophanase. Thus, a physiological role is implied for the enzyme polynculeotide phosphorylase.
mesh_terms: D000244:Adenosine Diphosphate / Q000096:biosynthesis; D002474:Cell-Free System; D002854:Chromatography, Paper; D004790:Enzyme Induction; D004926:Escherichia coli / Q000201:enzymology / Q000254:growth & development*; D005696:Galactosidases / Q000096:biosynthesis / Q000378:metabolism; D009154:Mutation; D010759:Phosphorus Isotopes; D011119:Polynucleotides / Q000378:metabolism; D011117:Polyribonucleotide Nucleotidyltransferase; D012316:RNA Nucleotidyltransferases / Q000378:metabolism*; D012329:RNA, Bacterial / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D013696:Temperature; D014368:Tryptophanase / Q000096:biosynthesis / Q000378:metabolism
chemical_list: D010759:Phosphorus Isotopes; D011119:Polynucleotides; D012329:RNA, Bacterial; D012333:RNA, Messenger; D000244:Adenosine Diphosphate; D012316:RNA Nucleotidyltransferases; D011117:Polyribonucleotide Nucleotidyltransferase; D005696:Galactosidases; D014368:Tryptophanase