Defective concatemer formation in cells infected with deoxyribonucleic acid-delay mutants of bacteriophage T4.
Nonpermissive host cells infected with phage T4 mutants in genes 52, 39, and 58 through 61 are shown to form short intracellular single-stranded deoxyribonucleic acid in contrast to wild-type infected cells, which form dimers and trimers of T4 genome size.
D002247:Carbon Isotopes; D002499:Centrifugation, Density Gradient; D002701:Chloramphenicol / Q000494:pharmacology; D003090:Coliphages / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D004261:DNA Replication; D004277:DNA, Single-Stranded / Q000096:biosynthesis; D004279:DNA, Viral / Q000032:analysis / Q000096:biosynthesis*; D004926:Escherichia coli / Q000378:metabolism*; D006918:Hydroxyurea / Q000494:pharmacology; D009154:Mutation; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014316:Tritium
D002247:Carbon Isotopes; D004277:DNA, Single-Stranded; D004279:DNA, Viral; D014316:Tritium; D002701:Chloramphenicol; D013936:Thymidine; D006918:Hydroxyurea