Increase in sensitivity to antibiotics and lysozyme on deletion of lipopolysaccharides in Escherichia coli strains.
Lipopolysaccharides on the cell surface of Escherichia coli prevent penetration of lysozyme or certain low-molecular-weight drugs.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003090:Coliphages; D004926:Escherichia coli / Q000032:analysis / Q000187:drug effects*; D007933:Leucomycins / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000032:analysis*; D008242:Lysogeny; D009113:Muramidase / Q000494:pharmacology*; D009154:Mutation; D009675:Novobiocin / Q000494:pharmacology; D011135:Polysaccharides, Bacterial / Q000032:analysis*
D000900:Anti-Bacterial Agents; D007933:Leucomycins; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial; D009675:Novobiocin; D009113:Muramidase