Biosynthesis of N-(purin-6-ylcarbamoyl)-L-threonine riboside. Incorporation of L-threonine in vivo into modified nucleoside of transfer ribonucleic acid.
l-[U-(14)C]Threonine is incorporated into N-(purin-6-ylcarbamoyl)-l-threonine riboside of rat liver and Escherichia coli tRNA. A pathway is suggested for the biosynthesis of this nucleoside.
D000241:Adenosine / Q000378:metabolism / Q000031:analogs & derivatives; D000818:Animals; D002219:Carbamates; D002247:Carbon Isotopes; D002854:Chromatography, Paper; D003562:Cytidine / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D006151:Guanosine / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D011687:Purines; D012329:RNA, Bacterial / Q000096:biosynthesis*; D012343:RNA, Transfer / Q000096:biosynthesis*; D051381:Rats; D012263:Ribonucleosides / Q000096:biosynthesis*; D013912:Threonine / Q000378:metabolism*; D014529:Uridine / Q000378:metabolism
D002219:Carbamates; D002247:Carbon Isotopes; D011687:Purines; D012329:RNA, Bacterial; D012263:Ribonucleosides; D006151:Guanosine; C003268:N(6)-(N-threonylcarbonyl)adenosine; D013912:Threonine; D003562:Cytidine; D012343:RNA, Transfer; D000241:Adenosine; D014529:Uridine