Treatment of muscle cramps during maintenance haemodialysis.
The effect of a slowly released oral preparation of sodium chloride (Slow Sodium) on the frequency and severity of muscle cramps, on blood pressure, and on body weight was compared with that of placebo in a double-blind cross-over trial in 19 patients on maintenance haemodialysis for end-stage renal failure. A significant reduction in both the frequency and severity of cramps was found while the patients were receiving the sodium chloride preparation and no significant alteration in blood pressure or body weight was detected.
D058186:Acute Kidney Injury / Q000628:therapy; D001794:Blood Pressure; D001835:Body Weight; D002986:Clinical Trials as Topic; D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D008297:Male; D009120:Muscle Cramp / Q000209:etiology / Q000517:prevention & control*; D010919:Placebos; D011187:Posture; D006435:Renal Dialysis / Q000009:adverse effects*; D012965:Sodium Chloride / Q000008:administration & dosage / Q000627:therapeutic use
D003692:Delayed-Action Preparations; D010919:Placebos; D012965:Sodium Chloride