title: Biochemical studies and therapy in subacute necrotizing encephalomyelopathy (Leigh's syndrome).
mesh_terms: D001710:Biotin / Q000627:therapeutic use; D001921:Brain / Q000201:enzymology; D001933:Brain Stem / Q000201:enzymology; D002262:Carboxy-Lyases / Q000378:metabolism; D004678:Encephalomalacia / Q000188:drug therapy / Q000201:enzymology / Q000235:genetics; D006801:Humans; D007223:Infant; D008607:Intellectual Disability / Q000188:drug therapy / Q000201:enzymology / Q000235:genetics; D008025:Ligases / Q000378:metabolism; D008099:Liver / Q000201:enzymology; D008297:Male; D011596:Psychomotor Disorders / Q000188:drug therapy / Q000201:enzymology / Q000235:genetics; D011773:Pyruvates / Q000378:metabolism; D013831:Thiamine / Q000627:therapeutic use; D008063:Thioctic Acid / Q000627:therapeutic use
chemical_list: D011773:Pyruvates; D001710:Biotin; D008063:Thioctic Acid; D002262:Carboxy-Lyases; D008025:Ligases; D013831:Thiamine