title: A dominant constitutive phoR mutation in Escherichia coli.
abstract: A dominant constitutive mutation of the phoR locus controlling alkaline phosphatase synthesis in Escherichia coli is described. Its phenotype can be explained by the production of a poisonous subunit of the phoR gene product. The phoR gene product is inferred to consist of at least 3 or 4 subunits.
mesh_terms: D000469:Alkaline Phosphatase / Q000096:biosynthesis*; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology / Q000528:radiation effects; D005796:Genes; D005799:Genes, Dominant; D046911:Macromolecular Substances; D009154:Mutation; D009604:Nitrosoguanidines / Q000494:pharmacology; D011830:Radiation Effects; D013489:Suppression, Genetic; D014161:Transduction, Genetic; D014466:Ultraviolet Rays
chemical_list: D046911:Macromolecular Substances; D009604:Nitrosoguanidines; D000469:Alkaline Phosphatase