Failure of methylprednisolone to protect lead-sensitized rats against endotoxin.
Methylprednisolone, in doses that protect normal rats against endotoxin, has no effect in lead-sensitized rats.
D000085:Acetates; D000818:Animals; D004731:Endotoxins / Q000494:pharmacology*; D007114:Immunization; D007854:Lead / Q000494:pharmacology*; D007928:Lethal Dose 50; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D051381:Rats; D012706:Serratia marcescens / Q000276:immunology; D012772:Shock, Septic / Q000517:prevention & control*
D000085:Acetates; D004731:Endotoxins; D007854:Lead; D008775:Methylprednisolone