Rescue of DNA replication and bacteriophage production after infection with T4 DNA ligase mutants.
By preventing phage DNA synthesis during a critical period, conditions have been found under which DNA replication and phage production are rescued after infection with T4 DNA ligase mutants.
D002247:Carbon Isotopes; D002701:Chloramphenicol / Q000494:pharmacology; D003090:Coliphages / Q000201:enzymology* / Q000254:growth & development / Q000378:metabolism; D004247:DNA; D004254:DNA Nucleotidyltransferases / Q000378:metabolism; D004261:DNA Replication; D004279:DNA, Viral / Q000096:biosynthesis*; D004926:Escherichia coli; D005796:Genes; D008025:Ligases / Q000378:metabolism*; D009154:Mutation; D013696:Temperature; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014779:Virus Replication
D002247:Carbon Isotopes; D004279:DNA, Viral; D002701:Chloramphenicol; D004247:DNA; D004254:DNA Nucleotidyltransferases; D008025:Ligases; D013936:Thymidine