title: Effects of trimethoprim and its antagonists on RNA synthesis in Escherichia coli.
mesh_terms: D000241:Adenosine / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002247:Carbon Isotopes; D004336:Drug Antagonism; D004347:Drug Interactions; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D005998:Glycine / Q000494:pharmacology; D006151:Guanosine / Q000494:pharmacology; D008715:Methionine / Q000494:pharmacology; D011687:Purines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology*; D012329:RNA, Bacterial / Q000096:biosynthesis*; D013936:Thymidine / Q000494:pharmacology; D014295:Trimethoprim / Q000037:antagonists & inhibitors / Q000494:pharmacology; D014498:Uracil / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D002247:Carbon Isotopes; D005493:Folic Acid Antagonists; D011687:Purines; D011743:Pyrimidines; D012329:RNA, Bacterial; D006151:Guanosine; D014498:Uracil; D008715:Methionine; D014295:Trimethoprim; D000241:Adenosine; D005998:Glycine; D013936:Thymidine