Perifusion of isolated rat islets in vitro. Participation of the microtubular system in the biphasic release of insulin.
D000818:Animals; D003078:Colchicine / Q000494:pharmacology; D003594:Cytoplasmic Granules / Q000502:physiology; D003903:Deuterium; D005947:Glucose / Q000037:antagonists & inhibitors / Q000494:pharmacology; D066298:In Vitro Techniques; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000166:cytology / Q000187:drug effects / Q000378:metabolism* / Q000502:physiology; D008297:Male; D008722:Methods; D008870:Microtubules / Q000502:physiology*; D010477:Perfusion; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D013997:Time Factors; D014044:Tolbutamide / Q000494:pharmacology; D014747:Vinblastine / Q000494:pharmacology
D007328:Insulin; D014747:Vinblastine; D014044:Tolbutamide; D003903:Deuterium; D005947:Glucose; D003078:Colchicine