title: Teichoic acid of a stabilized L-form of Streptococcus pyogenes.
abstract: A stabilized L-form of Streptococcus pyogenes continues to synthesize glycerol teichoic acid. This polymer was obtained from S. pyogenes and its L-form, treated in identical fashion, and compared. Highly purified glycerol teichoic acid from only the L-form was found to be devoid of d-alanine and to have a shorter chain length. Otherwise, the glycerol teichoic acid from these two organisms was found to be a 1,3-phosphodiester-linked glycerophosphate polymer substituted with d-glucose. Evidence is presented that most, if not all, of the glycerol teichoic acid in this streptococcus lies between the wall and membrane. A possible need for the continued synthesis of a minute amount of glycerol teichoic acid by this L-form for survival is discussed in terms of the known function of teichoic acids in bacteria.
mesh_terms: D000409:Alanine / Q000032:analysis; D002458:Cell Fractionation; D002848:Chromatography, DEAE-Cellulose; D002850:Chromatography, Gel; D002854:Chromatography, Paper; D003470:Culture Media; D005947:Glucose / Q000032:analysis; D005990:Glycerol / Q000032:analysis; D006027:Glycosides / Q000378:metabolism*; D006868:Hydrolysis; D007740:L Forms / Q000378:metabolism*; D008722:Methods; D010710:Phosphates / Q000302:isolation & purification; D010756:Phosphoric Acids / Q000378:metabolism*; D010758:Phosphorus / Q000032:analysis; D012329:RNA, Bacterial / Q000302:isolation & purification; D013055:Spectrophotometry, Infrared; D013297:Streptococcus pyogenes / Q000378:metabolism*; D013682:Teichoic Acids / Q000032:analysis / Q000302:isolation & purification / Q000378:metabolism; D013696:Temperature
chemical_list: D003470:Culture Media; D006027:Glycosides; D010710:Phosphates; D010756:Phosphoric Acids; D012329:RNA, Bacterial; D013682:Teichoic Acids; D010758:Phosphorus; D005947:Glucose; D000409:Alanine; D005990:Glycerol