Mutagenic effect of temperature-sensitive mutants of gene 42 (dCMP hydroxymethylase) of bacteriophage T4.
Certain temperature-sensitive mutants of gene 42 of bacteriophage T4 increase the reversion rates of some rII mutants in the same genome by about 4 to 10 times. This effect was usually found at 34 C, an intermediate permissive temperature, but not at 28 C.
D003090:Coliphages / Q000201:enzymology* / Q000254:growth & development; D003597:Cytosine Nucleotides; D004267:DNA Viruses / Q000201:enzymology* / Q000254:growth & development; D004926:Escherichia coli; D005796:Genes; D009154:Mutation; D013696:Temperature; D014166:Transferases / Q000096:biosynthesis*
D003597:Cytosine Nucleotides; D014166:Transferases