Association of replicative T4 deoxyribonucleic acid and bacterial membranes.
Experiments utilizing CsCl density gradient analysis and radioactive labels specific for bacteriophage T4 deoxyribonucleic acid (DNA) and membranes have shown that replicative T4 DNA is associated with host membranes. The association is inhibited by chloramphenicol and takes place just prior to semi-conservative replication of the phage DNA.
D001426:Bacterial Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism*; D002499:Centrifugation, Density Gradient; D002701:Chloramphenicol / Q000494:pharmacology; D003090:Coliphages / Q000187:drug effects / Q000378:metabolism*; D004261:DNA Replication; D004279:DNA, Viral / Q000096:biosynthesis / Q000378:metabolism*; D003851:Deoxyribonucleases; D004926:Escherichia coli; D005990:Glycerol; D010759:Phosphorus Isotopes; D012260:Ribonucleases; D013997:Time Factors; D014316:Tritium
D001426:Bacterial Proteins; D004279:DNA, Viral; D010759:Phosphorus Isotopes; D014316:Tritium; D002701:Chloramphenicol; D003851:Deoxyribonucleases; D012260:Ribonucleases; D005990:Glycerol