The in vitro demonstration of the efficacy of trimethoprim as an antibacterial agent in a comparative bacteriological study of the effects of trimethoprim, sulfamethoxazole and the combination trimethoprim-sulfamethoxazole.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003352:Corynebacterium / Q000187:drug effects; D003470:Culture Media; D004058:Diffusion; D004338:Drug Combinations; D004352:Drug Resistance, Microbial; D004357:Drug Synergism; D004926:Escherichia coli / Q000187:drug effects; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009154:Mutation; D011513:Proteus mirabilis / Q000187:drug effects; D011743:Pyrimidines / Q000494:pharmacology*; D013210:Staphylococcus / Q000187:drug effects; D013420:Sulfamethoxazole / Q000494:pharmacology* / Q000627:therapeutic use; D013449:Sulfonamides / Q000494:pharmacology; D014295:Trimethoprim / Q000494:pharmacology / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D003470:Culture Media; D004338:Drug Combinations; D005493:Folic Acid Antagonists; D011743:Pyrimidines; D013449:Sulfonamides; D014295:Trimethoprim; D013420:Sulfamethoxazole