title: Aqueous central cavity in aspartate transcarbamylase from Escherichia coli.
abstract: A three-dimensional x-ray diffraction study of aspartate transcarbamylase to 5.5-angstrom resolution, with the aid of four isomorphous heavy atom derivatives, indicates the presence of a central aqueous cavity approximating an oblate spheroid about 25 by 50 by 50 angstroms in dimension, within a molecule about 90 by 110 by 110 angstroms in largest dimensions.
mesh_terms: D001221:Aspartate Carbamoyltransferase; D004926:Escherichia coli / Q000201:enzymology*; D008961:Models, Structural; D011487:Protein Conformation; D014961:X-Ray Diffraction
chemical_list: D001221:Aspartate Carbamoyltransferase