Conditions influencing antimycin production by a Streptomyces species grown in chemically defined medium.
OPTIMAL CONDITIONS FOR PRODUCING CONSISTENT YIELDS OF ANTIMYCIN A IN CHEMICALLY DEFINED MEDIUM INCLUDED: (i) initial pH of 6.8 to 7.1; (ii) no iron supplementation; (iii) 2 g of dl-tryptophan per liter; and antibiotic extraction after 7 to 9 days of growth.
D000968:Antimycin A / Q000096:biosynthesis*; D003470:Culture Media; D006863:Hydrogen-Ion Concentration; D007501:Iron / Q000494:pharmacology; D013302:Streptomyces / Q000378:metabolism*; D013303:Streptomyces antibioticus / Q000187:drug effects / Q000378:metabolism; D013997:Time Factors; D014364:Tryptophan / Q000494:pharmacology
D003470:Culture Media; D000968:Antimycin A; D014364:Tryptophan; D007501:Iron