Detection of endotoxin in commercial L-asparaginase preparations by complement fixation and separation by chromatography.
D000818:Animals; D001215:Asparaginase / Q000032:analysis* / Q000494:pharmacology / Q000627:therapeutic use; D002460:Cell Line; D002845:Chromatography; D002850:Chromatography, Gel; D003168:Complement Fixation Tests; D003165:Complement System Proteins / Q000032:analysis; D003520:Cyclophosphamide / Q000627:therapeutic use; D004731:Endotoxins / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D004926:Escherichia coli / Q000276:immunology; D006168:Guinea Pigs / Q000276:immunology; D007110:Immunity, Active; D007942:Leukemia, Experimental / Q000188:drug therapy; D008070:Lipopolysaccharides; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D051379:Mice; D008807:Mice, Inbred BALB C; D008811:Mice, Inbred DBA; D012882:Skin Tests
D004731:Endotoxins; D008070:Lipopolysaccharides; D003520:Cyclophosphamide; D003165:Complement System Proteins; D001215:Asparaginase; D008727:Methotrexate