Incorporation of cis-hydroxyproline into collagen by tendon cells. Failure of the intracellular collagen to assume a triple-helical conformation.
D000818:Animals; D002247:Carbon Isotopes; D002478:Cells, Cultured / Q000378:metabolism; D002642:Chick Embryo; D002850:Chromatography, Gel; D003094:Collagen / Q000096:biosynthesis* / Q000378:metabolism; D003470:Culture Media; D006614:Hindlimb; D006909:Hydroxyproline / Q000378:metabolism*; D010434:Pepsin A; D010452:Peptide Biosynthesis; D010455:Peptides / Q000378:metabolism; D011392:Proline / Q000378:metabolism; D014176:Protein Biosynthesis; D011487:Protein Conformation; D011506:Proteins / Q000378:metabolism; D013329:Structure-Activity Relationship; D013710:Tendons / Q000166:cytology / Q000378:metabolism*; D013997:Time Factors
D002247:Carbon Isotopes; D003470:Culture Media; D010455:Peptides; D011506:Proteins; D003094:Collagen; D011392:Proline; D010434:Pepsin A; D006909:Hydroxyproline