title: The immunopathology of epidermolysis bullosa acquisita.
abstract: The acquired type of epidermolysis bullosa, epidermolysis bullosa acquisita, has a high incidence of associated systemic disorders. Two patients with epidermolysis bullosa acquisita were investigated by clinical, histochemical and immunologic methods. The histochemical findings confirmed earlier reported dermal changes. Both patients had in vivo IgG and the C(3) component of complement localized in the basement-membrane zone.
mesh_terms: D000328:Adult; D000368:Aged; D001485:Basement Membrane / Q000473:pathology; D001706:Biopsy; D003165:Complement System Proteins; D003424:Crohn Disease / Q000150:complications; D004820:Epidermolysis Bullosa / Q000150:complications / Q000188:drug therapy / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007421:Intestine, Small / Q000473:pathology; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D012867:Skin / Q000293:injuries / Q000473:pathology; D014947:Wounds and Injuries / Q000150:complications
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D003165:Complement System Proteins; D011241:Prednisone