title: Studies on the conversion of proinsulin to insulin. II. Evidence for a chymotrypsin-like cleavage in the connecting peptide region of insulin precursors in the rat.
mesh_terms: D000085:Acetates / Q000494:pharmacology; D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002918:Chymotrypsin; D003348:Cortisone / Q000494:pharmacology; D004590:Electrophoresis, Paper; D005561:Formates; D005973:Glutamine / Q000032:analysis; D007328:Insulin / Q000378:metabolism*; D007515:Islets of Langerhans / Q000378:metabolism; D007930:Leucine / Q000378:metabolism; D008297:Male; D008956:Models, Chemical; D010179:Pancreas / Q000187:drug effects / Q000378:metabolism*; D010455:Peptides / Q000032:analysis / Q000302:isolation & purification / Q000378:metabolism*; D011384:Proinsulin / Q000096:biosynthesis / Q000378:metabolism*; D051381:Rats; D013861:Thiocyanates; D014316:Tritium; D014357:Trypsin
chemical_list: D000085:Acetates; D000596:Amino Acids; D005561:Formates; D007328:Insulin; D010455:Peptides; D013861:Thiocyanates; D005973:Glutamine; D014316:Tritium; D011384:Proinsulin; D002918:Chymotrypsin; D014357:Trypsin; D007930:Leucine; D003348:Cortisone