The inhibition in vitro of bacterial DNA polymerases and RNA polymerase by antimalarial 8-aminoquinolines and by chloroquine.
D000588:Amines; D000818:Animals; D000962:Antimalarials; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D002738:Chloroquine; D004247:DNA; D004254:DNA Nucleotidyltransferases / Q000037:antagonists & inhibitors*; D004269:DNA, Bacterial; D004926:Escherichia coli / Q000201:enzymology; D006900:Hydroxylation; D008274:Magnesium; D008837:Micrococcus / Q000201:enzymology; D009711:Nucleotides; D009994:Osmolar Concentration; D011804:Quinolines; D012316:RNA Nucleotidyltransferases / Q000037:antagonists & inhibitors*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013698:Templates, Genetic; D013950:Thymus Gland; D013997:Time Factors
D000588:Amines; D000962:Antimalarials; D004269:DNA, Bacterial; D009711:Nucleotides; D011804:Quinolines; D002738:Chloroquine; D004247:DNA; D004254:DNA Nucleotidyltransferases; D012316:RNA Nucleotidyltransferases; D008274:Magnesium