title: ThelonGene and Degradation of β-Galactosidase Nonsense Fragments
abstract: N-terminal beta-galactosidase fragments are rapidly degraded in growing cells of Escherichia coli. Mutations in the lon gene are sufficient to enhance the stability of these polypeptides.
mesh_terms: D004926:Escherichia coli / Q000201:enzymology / Q000378:metabolism* / Q000528:radiation effects; D005696:Galactosidases / Q000378:metabolism*; D005796:Genes; D008040:Genetic Linkage; D009154:Mutation; D010455:Peptides / Q000378:metabolism*; D010641:Phenotype; D011489:Protein Denaturation; D011830:Radiation Effects; D011995:Recombination, Genetic; D014161:Transduction, Genetic; D014466:Ultraviolet Rays
chemical_list: D010455:Peptides; D005696:Galactosidases