Class, subclass, and allelic exclusion of membrane-bound Ig of human B lymphocytes.
Membrane-bound immunoglobulins of peripheral blood B lymphocytes and of lymphocytes from an IgG chronic lymphocytic leukemia showed restriction to one immunoglobulin class, one IgG subclass, and one Gm allotype. Certain antigens in the C-terminal part of IgG Fc were not exposed on the cell surface.
D000483:Alleles; D002462:Cell Membrane / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007111:Immunity, Cellular; D007125:Immunogenetics; D007074:Immunoglobulin G / Q000145:classification; D007136:Immunoglobulins / Q000145:classification*; D066298:In Vitro Techniques; D007519:Isoantigens; D007945:Leukemia, Lymphoid / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*
D007074:Immunoglobulin G; D007136:Immunoglobulins; D007519:Isoantigens