The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions.
D000818:Animals; D001665:Binding Sites; D002248:Carbon Monoxide / Q000378:metabolism; D003486:Cyanides; D003577:Cytochrome P-450 Enzyme System; D005021:Ethylamines; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007521:Isocitrate Dehydrogenase; D008745:Methylation; D008797:Metyrapone; D008862:Microsomes, Liver / Q000187:drug effects*; D009019:Morphinans; D010084:Oxidation-Reduction; D010634:Phenobarbital; D011335:Proadifen; D011549:Pseudomonas / Q000378:metabolism; D051381:Rats; D013057:Spectrum Analysis
D003486:Cyanides; D005021:Ethylamines; D009019:Morphinans; D002248:Carbon Monoxide; D003577:Cytochrome P-450 Enzyme System; D011335:Proadifen; D007521:Isocitrate Dehydrogenase; D010634:Phenobarbital; D008797:Metyrapone