Multiple myeloma: development of plasma cell sarcoma during apparently successful chemotherapy.
Three patients with multiple myeloma who developed a plasma cell sarcoma during apparently successful chemothapy are described. It is postulated that the chemotherapy induced the sarcomatous change.
D000368:Aged; D001536:Bence Jones Protein; D001853:Bone Marrow / Q000473:pathology; D003520:Cyclophosphamide / Q000009:adverse effects; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008175:Lung Neoplasms / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008558:Melphalan / Q000009:adverse effects; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000188:drug therapy; D009588:Nitrogen Mustard Compounds / Q000009:adverse effects*; D010997:Pleural Neoplasms / Q000473:pathology; D013997:Time Factors
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D009588:Nitrogen Mustard Compounds; D003520:Cyclophosphamide; D001536:Bence Jones Protein; D008558:Melphalan