Spontaneous whole brain slow potential changes during recovery from experimental neurosurgery.
Prolonged, nonlocalized brain slow potential changes, frequently associated with cortical spreading depression, occur spontaneously during 5 days following brain implant surgery in rats. These potentials are accompanied by reductions in multiple nerve cell activity and reductions in behavioral motility. The method used in this study provides a tool for evaluating recovery from neurosurgical trauma or other brain injuries, and for testing procedures that facilitate or impede this process.
D000818:Animals; D001921:Brain / Q000502:physiology / Q000601:surgery*; D002540:Cerebral Cortex / Q000502:physiology; D013181:Cortical Spreading Depression; D004567:Electrodes, Implanted; D007031:Hypothalamus / Q000502:physiology; D008297:Male; D008564:Membrane Potentials; D051381:Rats; D013238:Stereotaxic Techniques