title: "Periplasmic" location of a  -lactamase specified either by a plasmid or a chromosomal gene in Escherichia coli.
abstract: Type IIIa beta-lactamase (TEM beta-lactamase) was "periplasmic" in Escherichia coli K-12 regardless of whether its gene was chromosomal or carried on an R factor.
mesh_terms: D002876:Chromosomes, Bacterial; D004926:Escherichia coli / Q000201:enzymology*; D005111:Extrachromosomal Inheritance; D005796:Genes; D009995:Osmosis; D010405:Penicillinase / Q000096:biosynthesis*
chemical_list: D010405:Penicillinase