title: Kidney preservation by surface cooling: analysis of 130 transplants.
abstract: An analysis of 130 consecutive cadaveric renal transplants has shown the effectiveness of simple surface cooling of organs before transplantation. The primary graft failure rate was 10%, and kidneys could be stored for periods of up to 12 hours including warm ischaemia times of 150 minutes. Forty-eight patients received haemodialysis before transplantation and 78 patients received peritoneal dialysis. There were significant differences in the incidence of tubular necrosis in the two groups: these may have been linked to the differences in fluid and osmotic load presented to the transplants.
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology; D003080:Cold Temperature; D003404:Creatinine / Q000378:metabolism; D006084:Graft Rejection; D006801:Humans; D007668:Kidney / Q000378:metabolism; D016030:Kidney Transplantation; D009336:Necrosis / Q000453:epidemiology; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D013997:Time Factors; D014021:Tissue Preservation; D014184:Transplantation, Homologous
chemical_list: D003404:Creatinine