title: Failure of repeated or prolonged immunization to stimulate the production of antibody of more than one specificity by individual spleen ceells.
mesh_terms: D000818:Animals; D000917:Antibody Formation; D000918:Antibody Specificity; D000921:Antibody-Producing Cells; D001152:Arsenicals; D010856:Columbidae / Q000276:immunology; D003429:Cross Reactions; D004912:Erythrocytes / Q000276:immunology; D006462:Hemolytic Plaque Technique; D007106:Immune Sera; D011817:Rabbits; D012756:Sheep / Q000276:immunology; D013154:Spleen / Q000166:cytology / Q000276:immunology*
chemical_list: D001152:Arsenicals; D007106:Immune Sera