title: Trimethoprim-induced accumulation of guanosine tetraphosphate (ppGpp) in Escherichia coli.
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001120:Arginine / Q000378:metabolism; D002247:Carbon Isotopes; D002855:Chromatography, Thin Layer; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D005493:Folic Acid Antagonists / Q000494:pharmacology*; D005827:Genetics, Microbial; D006150:Guanine Nucleotides / Q000378:metabolism*; D009154:Mutation; D010710:Phosphates / Q000378:metabolism; D010759:Phosphorus Isotopes; D011743:Pyrimidines / Q000494:pharmacology*; D012329:RNA, Bacterial / Q000096:biosynthesis; D014295:Trimethoprim / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D002247:Carbon Isotopes; D005493:Folic Acid Antagonists; D006150:Guanine Nucleotides; D010710:Phosphates; D010759:Phosphorus Isotopes; D011743:Pyrimidines; D012329:RNA, Bacterial; D001120:Arginine; D014295:Trimethoprim