Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.
D000818:Animals; D000963:Antimetabolites / Q000378:metabolism*; D001551:Benz(a)Anthracenes / Q000494:pharmacology; D001665:Binding Sites; D002273:Carcinogens / Q000378:metabolism*; D004790:Enzyme Induction; D004988:Ethers, Cyclic / Q000378:metabolism; D006168:Guinea Pigs; D006801:Humans; D006836:Hydro-Lyases / Q000302:isolation & purification / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008566:Membranes / Q000201:enzymology; D008748:Methylcholanthrene / Q000494:pharmacology; D051379:Mice; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D010634:Phenobarbital / Q000494:pharmacology; D011467:Prostate / Q000187:drug effects; D011471:Prostatic Neoplasms / Q000209:etiology; D013045:Species Specificity; D013329:Structure-Activity Relationship
D000963:Antimetabolites; D001551:Benz(a)Anthracenes; D002273:Carcinogens; D004988:Ethers, Cyclic; D008748:Methylcholanthrene; D006836:Hydro-Lyases; D010634:Phenobarbital