Immunodepression by Rowson-Parr virus in mice. II. Effect of Rowson-Parr virus infection on the antibody response to sheep red cells in vivo and in vitro.
The effects of infection with Rowson-Parr virus (RPV), an associated virus present in Friend virus (FV) preparations, on the splenic plaque-forming cell response to sheep red cells in adult mice and on the plaque-forming cell response of peritoneal cells in vitro have been investigated. The results support the hypothesis that RPV might be responsible for a considerable proportion of the early immunodepressive effects caused by FV preparations.
D000818:Animals; D000917:Antibody Formation; D000941:Antigens; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D005622:Friend murine leukemia virus; D006462:Hemolytic Plaque Technique; D007117:Immunization, Secondary; D007165:Immunosuppression Therapy; D008214:Lymphocytes / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010537:Peritoneum / Q000166:cytology; D012526:Satellite Viruses / Q000276:immunology*; D012756:Sheep / Q000276:immunology; D013154:Spleen / Q000166:cytology
D000941:Antigens