title: Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions.
abstract: Bilateral electrolytic lesions in the suprachiasmatic nuclei permanently eliminated nocturnal and circadian rhythms in drinking behavior and locomotor activity of albino rats. The generation of 24-hr behavioral rhythms and the entrainment of these rhythms to the light-dark cycle of environmental illumination may be coordinated by neurons in the suprachiasmatic region of the rat brain. Destruction of the medial preoptic area had no effect on 24-hr drinking rhythms.
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D001766:Blindness / Q000503:physiopathology; D002369:Castration; D002940:Circadian Rhythm; D004327:Drinking Behavior; D005260:Female; D007031:Hypothalamus / Q000502:physiology*; D009043:Motor Activity; D009897:Optic Chiasm / Q000502:physiology; D051381:Rats; D013238:Stereotaxic Techniques