title: Lymphocyte sensitization in asthma with special reference to nature and identity of intrinsic form.
abstract: Studies of lymphocyte sensitization in patients with asthma showed that the intrinsic and extrinsic forms of the disease fell into two distinct groups. Intrinsic disease showed a general sensitization to a number of non-specific antigens, while the extrinsic form had only slight elevation above normal values. These findings suggest that intrinsic asthma results from a defect of general immunity, whereas extrinsic asthma is a specific sensitization.
mesh_terms: D000328:Adult; D000818:Animals; D000937:Antigen-Antibody Reactions; D000941:Antigens; D001232:Aspergillus fumigatus / Q000276:immunology; D001249:Asthma / Q000188:drug therapy / Q000209:etiology / Q000276:immunology* / Q000503:physiopathology; D002464:Cell Migration Inhibition; D004391:Dust; D005260:Female; D006168:Guinea Pigs / Q000276:immunology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*; D008264:Macrophages / Q000276:immunology; D008297:Male; D008875:Middle Aged; D011058:Pollen; D013256:Steroids / Q000627:therapeutic use
chemical_list: D000941:Antigens; D004391:Dust; D013256:Steroids