Persistence of methadone-3H and metabolite in rat brain after a single injection and its implications on pharmacological tolerance.
D000284:Administration, Oral; D000818:Animals; D001923:Brain Chemistry; D002540:Cerebral Cortex / Q000378:metabolism*; D055598:Chemical Phenomena; D002621:Chemistry; D002855:Chromatography, Thin Layer; D004361:Drug Tolerance; D007279:Injections, Subcutaneous; D008297:Male; D008691:Methadone / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism*; D011759:Pyrrolidines / Q000032:analysis / Q000378:metabolism; D051381:Rats; D013997:Time Factors
D011759:Pyrrolidines; D008691:Methadone