title: Amber mutant of bacteriophage Q  capable of causing overproduction of Q  replicase.
abstract: Amber mutant amB86 of bacteriophage Qbeta is capable of causing the production of five to eight times more viral replicase than wild-type phage. Su(-) bacteria infected with the mutant can carry the viral RNA in a plasmid-like state for many bacterial generations.
mesh_terms: D002474:Cell-Free System; D003090:Coliphages / Q000201:enzymology* / Q000254:growth & development; D012321:DNA-Directed RNA Polymerases / Q000096:biosynthesis* / Q000378:metabolism; D004926:Escherichia coli / Q000254:growth & development; D005111:Extrachromosomal Inheritance; D005796:Genes; D009154:Mutation; D014176:Protein Biosynthesis; D012328:RNA Viruses / Q000201:enzymology / Q000254:growth & development; D014316:Tritium; D014500:Uracil Nucleotides / Q000378:metabolism; D014764:Viral Proteins / Q000096:biosynthesis
chemical_list: D014500:Uracil Nucleotides; D014764:Viral Proteins; D014316:Tritium; D012321:DNA-Directed RNA Polymerases