Treatment of Bacteroides infection with clindamycin-2-phosphate.
Eighteen patients with serious Bacteroides infections were treated with systemic clindamycin-2-phosphate. Sixteen patients recovered without complications while two patients died. Few side effects were noted. The infections treated included septic abortion, posthysterectomy infections, pelvic inflammatory disease, perforation of the bowel, postoperative complications of abdominal surgery and pancreatic abscess. The clinical usefulness of this drug in treating Bacteroides infection is confirmed.
D000031:Abortion, Septic / Q000188:drug therapy; D000038:Abscess / Q000188:drug therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D001442:Bacteroides Infections / Q000188:drug therapy* / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D002981:Clindamycin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage; D006311:Hearing Disorders / Q000139:chemically induced; D006801:Humans; D007223:Infant; D007416:Intestinal Perforation / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009864:Ontario; D009943:Organophosphorus Compounds / Q000009:adverse effects / Q000627:therapeutic use; D010182:Pancreatic Diseases / Q000188:drug therapy; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy; D010538:Peritonitis / Q000188:drug therapy; D011183:Postoperative Complications / Q000188:drug therapy; D011247:Pregnancy; D012189:Retrospective Studies
D005839:Gentamicins; D009943:Organophosphorus Compounds; D002981:Clindamycin; C007084:clindamycin phosphate