title: Interference of griseofulvin with the segregation of chromosomes at mitosis in diploid Aspergillus nidulans.
abstract: Low concentrations of the antibiotic griseofulvin were found to cause increased frequencies of somatic segregation due to chromosome nondisjunction in a diploid strain of Aspergillus nidulans.
mesh_terms: D001233:Aspergillus nidulans / Q000166:cytology* / Q000187:drug effects / Q000254:growth & development; D001562:Benzimidazoles / Q000494:pharmacology; D002875:Chromosomes / Q000187:drug effects*; D004171:Diploidy; D004352:Drug Resistance, Microbial; D006118:Griseofulvin / Q000494:pharmacology*; D008938:Mitosis / Q000187:drug effects; D009154:Mutation
chemical_list: D001562:Benzimidazoles; D006118:Griseofulvin