Catabolie repression in inhibition of beta-galactosidase synthesis by Escherichia coli in the presence of agents producing translation errors.
Studies were made of the synthesis of beta-galactosidase by Escherichia coli in the presence of 5-fluorouracil, streptomycin, and subinhibitory concentrations of chloramphenicol. The preferential inhibition of beta-galactosidase synthesis observed in the presence of the above drugs was found to be caused by catabolite repression.
D002701:Chloramphenicol / Q000494:pharmacology*; D004926:Escherichia coli / Q000201:enzymology*; D005472:Fluorouracil / Q000494:pharmacology*; D005696:Galactosidases / Q000096:biosynthesis*; D014176:Protein Biosynthesis / Q000187:drug effects*; D013307:Streptomycin / Q000494:pharmacology*
D002701:Chloramphenicol; D005696:Galactosidases; D005472:Fluorouracil; D013307:Streptomycin