Evidence for a rate-determining proton abstraction in the serine deaminase reaction of the beta 2 subunit of tryptophan synthetase.
D003903:Deuterium; D004926:Escherichia coli / Q000201:enzymology*; D007700:Kinetics; D012695:L-Serine Dehydratase / Q000378:metabolism*; D046911:Macromolecular Substances; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008433:Mathematics; D008956:Models, Chemical; D011522:Protons; D011732:Pyridoxal Phosphate / Q000378:metabolism; D012545:Schiff Bases; D012694:Serine / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D014367:Tryptophan Synthase / Q000378:metabolism*
D046911:Macromolecular Substances; D011522:Protons; D012545:Schiff Bases; D012694:Serine; D011732:Pyridoxal Phosphate; D003903:Deuterium; D014367:Tryptophan Synthase; D012695:L-Serine Dehydratase