Growth inhibitory activity of deoxyribonucleic acid-containing factor(s) isolated from lepromatous lesions.
Deoxyribonucleic acid-containing factor(s) isolated from Mycobacterium leprae suspensions obtained from lepromas of nine patients showed growth inhibitory activity against Micrococcus and both orange-red-pigmented and coccoid mutants of mycobacteria. No growth inhibition was observed for parent mycobacterial species, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus epidermidis.
D004279:DNA, Viral / Q000032:analysis; D007918:Leprosy / Q000382:microbiology; D008854:Microscopy, Electron; D009160:Mycobacteriophages / Q000032:analysis / Q000302:isolation & purification* / Q000648:ultrastructure; D009166:Mycobacterium leprae / Q000254:growth & development
D004279:DNA, Viral