title: Half-of-the sites reactivity and negative co-operativity: the case of yeast glyceraldehyde 3-phosphate dehydrogenase.
mesh_terms: D000478:Alkylation; D000577:Amides; D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D001665:Binding Sites; D002250:Carbon Radioisotopes; D002729:Chloromercuribenzoates / Q000494:pharmacology; D003545:Cysteine; D004591:Electrophoresis, Polyacrylamide Gel; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000032:analysis* / Q000037:antagonists & inhibitors / Q000378:metabolism; D007461:Iodoacetates / Q000494:pharmacology; D007700:Kinetics; D008954:Models, Biological; D008961:Models, Structural; D011485:Protein Binding; D011487:Protein Conformation; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D013056:Spectrophotometry, Ultraviolet; D013439:Sulfhydryl Reagents / Q000494:pharmacology; D013997:Time Factors; D014961:X-Ray Diffraction
chemical_list: D000577:Amides; D000596:Amino Acids; D002250:Carbon Radioisotopes; D002729:Chloromercuribenzoates; D007461:Iodoacetates; D013439:Sulfhydryl Reagents; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D003545:Cysteine