title: Effect of molybdenum starvation and tungsten on the synthesis of nitrogenase components in Klebsiella pneumonia.
abstract: Klebsiella pneumoniae M5a1 grows well in the presence or absence of molybdenum in media containing excess NH(4) (+). However, growth on N(2) is completely dependent on the presence of molybdenum in the medium. Tungstate competes with the molybdate requirement during growth on N(2). In molybdenum-depleted medium, neither protein component of nitrogenase is active and neither component can be detected antigenically. These data provide evidence that molybdenum is an inducer of nitrogenase synthesis.
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis*; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000254:growth & development / Q000276:immunology / Q000378:metabolism*; D008982:Molybdenum / Q000378:metabolism*; D014414:Tungsten / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D008982:Molybdenum; D014414:Tungsten