title: Semisynthetic cephalosporins. Synthesis and structure-activity relationships of 7-mandelamido-3-cephem-4-carboxylic acids.
mesh_terms: D000577:Amides / Q000097:blood / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D001419:Bacteria / Q000187:drug effects; D002511:Cephalosporins / Q000097:blood / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D004285:Dogs; D004927:Escherichia coli Infections / Q000188:drug therapy; D007710:Klebsiella Infections / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D008333:Mandelic Acids / Q000097:blood / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D051379:Mice; D008826:Microbial Sensitivity Tests; D011817:Rabbits; D013203:Staphylococcal Infections / Q000188:drug therapy; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D000577:Amides; D002511:Cephalosporins; D008333:Mandelic Acids