Regulation of newly evolved enzymes. I. Selection of a novel lactase regulated by lactose in Escherichia coli.
Thirty-four lactose-utilizing strains of E. coli were selected from a lac Z deletion strain. In 31 of these, the synthesis of the newly evolved lactase is regulated by lactose. The lactase activity in all the strains is indistinguishable from the ebg(+) activity identified by Campbell, Lengyel and Langridge (1973).
D001426:Bacterial Proteins / Q000096:biosynthesis; D003470:Culture Media; D004790:Enzyme Induction; D004926:Escherichia coli / Q000201:enzymology*; D005696:Galactosidases / Q000096:biosynthesis*; D007785:Lactose / Q000378:metabolism*; D009876:Operon; D013696:Temperature; D013997:Time Factors
D001426:Bacterial Proteins; D003470:Culture Media; D005696:Galactosidases; D007785:Lactose