title: Genetic recombination in bacteriophage phi chi 174.
abstract: Genetic recombination in bacteriophage phiX174 usually takes place early in the infection process and involves two parental replicative form (double-stranded) DNA molecules. The host recA protein is required; none of the nine known phiX174 cistron products is essential. The products of a single recombination event are nonreciprocal and asymmetric. Typically, only one of the parental genotypes and one recombinant genotype are recovered from a single cell. An alternative, less efficient recombination mechanism which requires an active phiX174 cistron A protein is observed in the absence of the host recA gene product.
mesh_terms: D000483:Alleles; D002874:Chromosome Mapping; D003090:Coliphages; D004267:DNA Viruses; D004926:Escherichia coli; D005838:Genotype; D009154:Mutation; D011995:Recombination, Genetic