Interspecies conversion of Clostridium botulinum type C to Clostridium novyi type A by bacteriophage.
When Clostridium botulinum type C is cured of its prophage it simultaneously ceases to produce toxin. This nontoxigenic culture can then be converted to another toxigenic bacterial species, Clostridium novyi type A or to toxigenic Clostridium botulinum types C or D, by specific bacteriophages. The toxigenicity and type of toxin produced by these cultures depends upon the continued presence of these bacteriophages.
D001435:Bacteriophages; D001905:Botulinum Toxins; D003013:Clostridium / Q000472:pathogenicity; D003014:Clostridium botulinum / Q000472:pathogenicity; D003470:Culture Media; D009154:Mutation; D013171:Spores, Bacterial
D003470:Culture Media; D001905:Botulinum Toxins