title: Ribosome precursors accumulated by Escherichia coli during incubation with cobalt chloride.
abstract: The ribonucleoprotein particles that accumulate during inhibition of Escherichia coli by CoCl(2) are ribosome precursors. The RNA that they contain can be transferred intact to completed ribosomes. The particles contain less protein than do ribosomes, but this protein appears identical with proteins from the appropriate ribosomal subunit. At least one of the particles is heterogeneous.
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism; D002250:Carbon Radioisotopes; D002455:Cell Division; D002499:Centrifugation, Density Gradient; D002712:Chlorides; D002852:Chromatography, Ion Exchange; D003035:Cobalt / Q000494:pharmacology*; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008239:Lysine / Q000378:metabolism; D012335:RNA, Ribosomal; D012270:Ribosomes / Q000378:metabolism*; D014316:Tritium; D014498:Uracil / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D002250:Carbon Radioisotopes; D002712:Chlorides; D012335:RNA, Ribosomal; D014316:Tritium; D003035:Cobalt; D014498:Uracil; D008239:Lysine