Conversion of progesterone to 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one by rat medical basal hypothalami and the effects of estradiol and stage of estrous cycle on the conversion.
D000818:Animals; D002369:Castration; D004958:Estradiol / Q000494:pharmacology*; D004971:Estrus; D005260:Female; D007031:Hypothalamus / Q000187:drug effects / Q000378:metabolism*; D066298:In Vitro Techniques; D010053:Ovary / Q000502:physiology; D011247:Pregnancy; D011277:Pregnanediones / Q000302:isolation & purification / Q000378:metabolism*; D011278:Pregnanes / Q000302:isolation & purification / Q000378:metabolism*; D011374:Progesterone / Q000302:isolation & purification / Q000378:metabolism*; D011865:Radioisotope Dilution Technique; D051381:Rats; D013347:Subcellular Fractions / Q000032:analysis; D014316:Tritium
D011277:Pregnanediones; D011278:Pregnanes; D014316:Tritium; D011374:Progesterone; D004958:Estradiol