Toxaphene insecticide: a complex biodegradable mixture.
Adsorption and gas-liquid chromatography separate toxaphene into at least 175 polychlorinated 10-carbon compounds including Cl(6), Cl(7), Cl(8), Cl(9), and Cl(10) derivatives. One toxic component is 2,2,5-endo,6-exo,8,9,10-heptachlorobornane. Rats metabolically dechlorinate toxaphene, removing about half of the chlorine from the technical insecticide and from each of seven subfractions of varying composition and toxicity.
D000818:Animals; D002250:Carbon Radioisotopes; D002713:Chlorine / Q000378:metabolism; D002849:Chromatography, Gas; D005243:Feces / Q000032:analysis; D007306:Insecticides / Q000378:metabolism*; D011865:Radioisotope Dilution Technique; D011868:Radioisotopes; D051381:Rats; D014112:Toxaphene / Q000032:analysis / Q000302:isolation & purification / Q000378:metabolism / Q000633:toxicity / Q000652:urine
D002250:Carbon Radioisotopes; D007306:Insecticides; D011868:Radioisotopes; D002713:Chlorine; D014112:Toxaphene