Peptidyl transferase inhibitors alter the covalent reaction of BrAcPhe-tRNA with the E. coli ribosome.
D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001665:Binding Sites; D002701:Chloramphenicol / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008034:Lincomycin / Q000494:pharmacology; D010649:Phenylalanine / Q000031:analogs & derivatives; D011485:Protein Binding; D011691:Puromycin; D012329:RNA, Bacterial / Q000378:metabolism*; D012343:RNA, Transfer / Q000378:metabolism*; D012270:Ribosomes / Q000187:drug effects / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet; D013307:Streptomycin / Q000494:pharmacology; D013752:Tetracycline / Q000494:pharmacology; D013997:Time Factors; D014316:Tritium
D000900:Anti-Bacterial Agents; D012329:RNA, Bacterial; D014316:Tritium; D010649:Phenylalanine; D011691:Puromycin; D002701:Chloramphenicol; D012343:RNA, Transfer; D008034:Lincomycin; D000217:Acyltransferases; D013752:Tetracycline; D013307:Streptomycin