Inhibition of fatty acid synthesis by the antibiotic cerulenin. Specific inactivation of beta-ketoacyl-acyl carrier protein synthetase.
D000164:Acremonium; D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000935:Antifungal Agents / Q000494:pharmacology*; D001426:Bacterial Proteins; D001665:Binding Sites; D002250:Carbon Radioisotopes; D002352:Carrier Proteins; D004926:Escherichia coli / Q000201:enzymology; D004988:Ethers, Cyclic / Q000494:pharmacology; D064429:Fatty Acid Synthases / Q000037:antagonists & inhibitors; D005227:Fatty Acids / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D008314:Malonates; D009161:Mycobacterium / Q000201:enzymology; D011485:Protein Binding / Q000187:drug effects; D014316:Tritium
D000935:Antifungal Agents; D001426:Bacterial Proteins; D002250:Carbon Radioisotopes; D002352:Carrier Proteins; D004988:Ethers, Cyclic; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D008314:Malonates; D014316:Tritium; D000217:Acyltransferases; D064429:Fatty Acid Synthases