Low-pathogenicity variant of lymphocytic choriomeningitis virus.
A noncytopathic virus has been isolated from a line of strain L mouse fibroblasts infected with lymphocytic choriomeningitis (LCM). This virus has low pathogenicity for mice and renders them immune to intracerebral challenge with virulent LCM virus.
D000818:Animals; D001921:Brain / Q000382:microbiology; D003588:Cytopathogenic Effect, Viral; D005455:Fluorescent Antibody Technique; D007109:Immunity; D007739:L Cells; D008216:Lymphocytic Choriomeningitis / Q000276:immunology; D008217:Lymphocytic choriomeningitis virus / Q000472:pathogenicity*; D051379:Mice; D010948:Viral Plaque Assay