title: Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 8: Clinical investigation. Use of a flexible dosage schedule in a double-blind comparison of loperamide with diphenoxylate in 614 patients suffering from acute diarrhea.
mesh_terms: D000208:Acute Disease; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000577:Amides / Q000008:administration & dosage / Q000627:therapeutic use; D000930:Antidiarrheals / Q000008:administration & dosage* / Q000627:therapeutic use; D001285:Atropine / Q000627:therapeutic use; D002214:Capsules; D002722:Chlorobenzenes / Q000008:administration & dosage / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D003967:Diarrhea / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D005765:Gastrointestinal Agents / Q000008:administration & dosage*; D006801:Humans; D007540:Isonipecotic Acids / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009570:Nitriles / Q000627:therapeutic use; D010880:Piperidines / Q000008:administration & dosage* / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D000577:Amides; D000930:Antidiarrheals; D002214:Capsules; D002722:Chlorobenzenes; D005765:Gastrointestinal Agents; D007540:Isonipecotic Acids; D009570:Nitriles; D010880:Piperidines; D001285:Atropine