title: Active site-directed inhibition of E. coli DNA-dependent RNA polymerase by pyridoxal 5'-phosphate.
mesh_terms: D001665:Binding Sites; D001894:Borohydrides; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors*; D004789:Enzyme Activation; D004926:Escherichia coli / Q000201:enzymology*; D007700:Kinetics; D009711:Nucleotides; D009943:Organophosphorus Compounds; D010084:Oxidation-Reduction; D011730:Pyridoxal; D011732:Pyridoxal Phosphate; D011733:Pyridoxamine; D011736:Pyridoxine; D012545:Schiff Bases; D013053:Spectrophotometry; D013056:Spectrophotometry, Ultraviolet; D014316:Tritium
chemical_list: D001894:Borohydrides; D009711:Nucleotides; D009943:Organophosphorus Compounds; D012545:Schiff Bases; D014316:Tritium; D011730:Pyridoxal; D011732:Pyridoxal Phosphate; D011733:Pyridoxamine; D012321:DNA-Directed RNA Polymerases; D011736:Pyridoxine