Interbacterial transfer of R factor in humans.
In vivo interbacterial transfer of R factor was observed in two patients. Resistance to ampicillin, tetracycline, streptomycin, and chloramphenicol was transferred from Escherichia coli in the intestine of a patient with shigellosis to a Shigella sonnei strain. In a second patient with partial ureteral obstruction, a resistant E. coli strain transferred ampicillin, tetracycline, and streptomycin resistance to a Proteus mirabilis strain.
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000187:drug effects*; D005111:Extrachromosomal Inheritance; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D011513:Proteus mirabilis / Q000187:drug effects*; D012764:Shigella sonnei / Q000187:drug effects*
D000900:Anti-Bacterial Agents