A comparative study of the effect of normal substrates and 5-iodo-2'-deoxyuridine triphosphate, a metabolic analog of thymidine triphosphate, on the inactivation of Escherichia coli deoxyribonucleic acid polymerase I and II by ultraviolet irradiation.
D000818:Animals; D002417:Cattle; D002712:Chlorides / Q000494:pharmacology; D004247:DNA; D004254:DNA Nucleotidyltransferases / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000528:radiation effects; D003854:Deoxyribonucleotides / Q000494:pharmacology; D003856:Deoxyuracil Nucleotides; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004926:Escherichia coli / Q000201:enzymology*; D005609:Free Radicals; D006863:Hydrogen-Ion Concentration; D007065:Idoxuridine / Q000494:pharmacology; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D011830:Radiation Effects; D013329:Structure-Activity Relationship; D013698:Templates, Genetic; D013942:Thymine Nucleotides / Q000378:metabolism*; D013950:Thymus Gland; D014316:Tritium; D014466:Ultraviolet Rays; D014500:Uracil Nucleotides / Q000008:administration & dosage / Q000494:pharmacology*
D002712:Chlorides; D003854:Deoxyribonucleotides; D003856:Deoxyuracil Nucleotides; D005609:Free Radicals; D013942:Thymine Nucleotides; D014500:Uracil Nucleotides; D014316:Tritium; C008144:5-iodo-2'-deoxyuridine triphosphate; D004247:DNA; D004254:DNA Nucleotidyltransferases; D008274:Magnesium; D007065:Idoxuridine