A study of the binding of thiamine diphosphate and thiochrome diphosphate to the pyruvate dehydrogenase multienzyme complex.
D001667:Binding, Competitive; D002250:Carbon Radioisotopes; D003956:Dialysis; D004735:Energy Transfer; D004926:Escherichia coli / Q000201:enzymology*; D005182:Flavin-Adenine Dinucleotide / Q000032:analysis / Q000378:metabolism; D007700:Kinetics; D008024:Ligands; D046911:Macromolecular Substances; D008433:Mathematics; D009943:Organophosphorus Compounds / Q000378:metabolism*; D010084:Oxidation-Reduction; D011485:Protein Binding; D011743:Pyrimidines / Q000378:metabolism*; D011768:Pyruvate Dehydrogenase Complex / Q000032:analysis / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013050:Spectrometry, Fluorescence; D013329:Structure-Activity Relationship; D013831:Thiamine / Q000031:analogs & derivatives; D013835:Thiamine Pyrophosphate / Q000378:metabolism*; D013844:Thiazoles / Q000378:metabolism
D002250:Carbon Radioisotopes; D008024:Ligands; D046911:Macromolecular Substances; D009943:Organophosphorus Compounds; D011743:Pyrimidines; D011768:Pyruvate Dehydrogenase Complex; D013844:Thiazoles; C009460:thiochrome diphosphate; D005182:Flavin-Adenine Dinucleotide; D013835:Thiamine Pyrophosphate; D013831:Thiamine