title: Spectroscopy of biological compounds with inelastic electron tunneling.
abstract: Metal-insulator-metal electron tunnel junctions can be doped with a solution of an organic compound by placing a drop of the solution on the insulator and spinning of the excess. Electrical measurement of the second derivative of voltage with respect to current, as a function of applied voltage, then gives a spectrum of vibrational modes equivalent to an infrared or Raman spectrum, but with the use of only micrograms of sample.
mesh_terms: D000818:Animals; D002417:Cattle; D004247:DNA; D004926:Escherichia coli; D007834:Lasers; D008722:Methods; D010649:Phenylalanine; D012329:RNA, Bacterial; D012343:RNA, Transfer; D012542:Scattering, Radiation; D013055:Spectrophotometry, Infrared; D013057:Spectrum Analysis; D013950:Thymus Gland; D014498:Uracil
chemical_list: D012329:RNA, Bacterial; D010649:Phenylalanine; D014498:Uracil; D004247:DNA; D012343:RNA, Transfer