title: Chloramphenicol acetyltransferases specified by fi minus R factors.
abstract: Chloramphenicol acetyltransferases specified by fi(-) (F fertility-noninhibiting) R factors were compared with those specified by the fi(+) R factors R1, 222, and R6-S. Three classes of enzyme were distinguished: class I was determined by group N fi(-) R factors and was indistinguishable from the enzyme determined by fi(+) R factors, class II was correlated with group W fi(-) R factors, and class III was determined by R387, an unclassified fi(-) R factor.
mesh_terms: D000123:Acetyltransferases / Q000378:metabolism*; D002701:Chloramphenicol; D004352:Drug Resistance, Microbial; D004926:Escherichia coli / Q000201:enzymology; D005111:Extrachromosomal Inheritance; D008826:Microbial Sensitivity Tests
chemical_list: D002701:Chloramphenicol; D000123:Acetyltransferases