In vivo effects of intraperitoneally injected L-asparaginase solution and L-asparaginase immobilized within semipermeable nylon microcapsules with emphasis on blood L-asparaginase, 'body' L-asparaginase, and plasma L-asparagine levels.
D000818:Animals; D001215:Asparaginase / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D001216:Asparagine / Q000097:blood*; D004926:Escherichia coli / Q000201:enzymology; D007274:Injections, Intraperitoneal; D007700:Kinetics; D008099:Liver / Q000201:enzymology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009757:Nylons; D010539:Permeability; D011485:Protein Binding; D012995:Solubility; D013050:Spectrometry, Fluorescence; D013997:Time Factors
D009757:Nylons; D001216:Asparagine; D001215:Asparaginase