Interference of griseofulvin with the segregation of chromosomes at mitosis in diploid Aspergillus nidulans.
Low concentrations of the antibiotic griseofulvin were found to cause increased frequencies of somatic segregation due to chromosome nondisjunction in a diploid strain of Aspergillus nidulans.
D001233:Aspergillus nidulans / Q000166:cytology* / Q000187:drug effects / Q000254:growth & development; D001562:Benzimidazoles / Q000494:pharmacology; D002875:Chromosomes / Q000187:drug effects*; D004171:Diploidy; D004352:Drug Resistance, Microbial; D006118:Griseofulvin / Q000494:pharmacology*; D008938:Mitosis / Q000187:drug effects; D009154:Mutation
D001562:Benzimidazoles; D006118:Griseofulvin