title: Size and structure of yeast chromosomal DNA.
abstract: Electron microscopic analysis indicates that yeast nuclear DNA can be isolated as linear molecules ranging in size from 50 mum (1.2 x 10(8) daltons) to 355 mum (8.4 x 10(8) daltons). Analysis indicates the data is consistent with the hypothesis that each yeast chromosome contains a single, linear DNA duplex. Mitochondrial DNA molecules have a contour length of 21 +/- 2 mum and are mostly linear.
mesh_terms: D002250:Carbon Radioisotopes; D002499:Centrifugation, Density Gradient; D002875:Chromosomes / Q000032:analysis*; D003090:Coliphages / Q000032:analysis; D004247:DNA / Q000302:isolation & purification*; D004272:DNA, Mitochondrial / Q000032:analysis; D004279:DNA, Viral; D008854:Microscopy, Electron; D008970:Molecular Weight; D009690:Nucleic Acid Conformation; D012441:Saccharomyces cerevisiae / Q000032:analysis*; D014316:Tritium
chemical_list: D002250:Carbon Radioisotopes; D004272:DNA, Mitochondrial; D004279:DNA, Viral; D014316:Tritium; D004247:DNA