The in vivo formation of N-nitrosamines in the rat bladder and their subsequent absorption.
Experiments are described which demonstrate the production of nitrosamine in vivo in the bladder of rats with experimental bladder infections. The absorption of nitrosamines from the bladder into the circulating blood is also described.
D000042:Absorption; D000818:Animals; D002250:Carbon Radioisotopes; D002849:Chromatography, Gas; D002855:Chromatography, Thin Layer; D006224:Cricetinae; D004123:Dimethylamines / Q000378:metabolism; D004927:Escherichia coli Infections / Q000378:metabolism; D008297:Male; D009566:Nitrates / Q000652:urine; D009602:Nitrosamines / Q000097:blood / Q000378:metabolism*; D010880:Piperidines / Q000378:metabolism; D051381:Rats; D014316:Tritium; D001743:Urinary Bladder / Q000378:metabolism*; D001745:Urinary Bladder Diseases / Q000378:metabolism
D002250:Carbon Radioisotopes; D004123:Dimethylamines; D009566:Nitrates; D009602:Nitrosamines; D010880:Piperidines; D014316:Tritium