Antibacterial effect of cysteine-nitrosothiol and possible percursors thereof.
The postulated intermediate of nitrite-myoglobin reaction, cysteine-nitrosothiol, was prepared and its antibacterial effect was tested on Salmonella strains, Streptococcus faecium, and spores and vegetative cells of Clostridium sporogenes. Cysteine-nitrosothiol showed a higher inhibitory effect than nitrite. Preliminary results on the effect of simultaneous use of nitrite and cysteine on Clostridium sporogenes spores were also presented.
D000438:Alcohols / Q000494:pharmacology; D000900:Anti-Bacterial Agents; D002452:Cell Count; D003013:Clostridium / Q000187:drug effects / Q000254:growth & development; D003545:Cysteine / Q000494:pharmacology*; D005503:Food Additives; D005516:Food Microbiology; D006358:Hot Temperature; D008460:Meat; D009573:Nitrites / Q000494:pharmacology; D009603:Nitroso Compounds / Q000494:pharmacology*; D012475:Salmonella / Q000187:drug effects / Q000254:growth & development; D012477:Salmonella enteritidis / Q000187:drug effects / Q000254:growth & development; D013045:Species Specificity; D013171:Spores, Bacterial / Q000187:drug effects; D013291:Streptococcus / Q000187:drug effects / Q000254:growth & development
D000438:Alcohols; D000900:Anti-Bacterial Agents; D005503:Food Additives; D009573:Nitrites; D009603:Nitroso Compounds; D003545:Cysteine