The bacteriological status of a specific-pathogen-free animal production building and of its staff and the microbiological integrity of the animals one year after the building was commissioned.
Bacteriological contamination of a specific-pathogen-free (SPF) animal production building was more extensive after one year of operation than at the time of commissioning. Throat and nose swabs taken from the staff yielded a number of undesirable organisms, in particular, on one occasion, a Group A streptococcus. It is recommended that a closer bacteriological scrutiny of the staff of SPF production buildings ought perhaps to be made in the light of these findings.
D000818:Animals; D001419:Bacteria / Q000302:isolation & purification*; D001431:Bacteriological Techniques; D004926:Escherichia coli / Q000302:isolation & purification; D005856:Germ-Free Life; D006168:Guinea Pigs; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006799:Housing, Animal; D006801:Humans; D051379:Mice; D008829:Microbiology; D009174:Mycoplasma / Q000302:isolation & purification; D009343:Neisseria / Q000302:isolation & purification; D009666:Nose / Q000382:microbiology*; D010614:Pharynx / Q000382:microbiology; D051381:Rats; D013210:Staphylococcus / Q000302:isolation & purification; D013242:Sterilization; D013291:Streptococcus / Q000302:isolation & purification; D013997:Time Factors; D000078329:Workforce