Effect of trifluoromethoxy, chlorodifluoromethoxy, and trifluoromethyl on the antimalarial activity of 5-benzyl- and 5-phenyl-2,4-diaminopyrimidines.
D000588:Amines / Q000138:chemical synthesis / Q000627:therapeutic use; D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis* / Q000627:therapeutic use; D002645:Chickens; D002713:Chlorine / Q000627:therapeutic use; D005461:Fluorine / Q000627:therapeutic use; D008288:Malaria / Q000188:drug therapy; D008738:Methyl Ethers / Q000138:chemical synthesis / Q000627:therapeutic use; D051379:Mice; D010962:Plasmodium berghei; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000627:therapeutic use; D013329:Structure-Activity Relationship
D000588:Amines; D000962:Antimalarials; D008738:Methyl Ethers; D011743:Pyrimidines; D005461:Fluorine; D002713:Chlorine