Radioautographic localization of labelled proteins after incubation of guinea-pig islets of Langerhans with (3H)tryptophan.
An analysis was made by electron-microscopic radioautography of the distribution of silver grains over storage granules of A(2) and B cells after incubation of isolated guinea-pig islets of Langerhans for 17h in the presence of [(3)H]tryptophan. A significant concentration of labelled proteins was present in the A(2) cell, but not in the B-cell granules.
D000818:Animals; D006168:Guinea Pigs; D007515:Islets of Langerhans / Q000378:metabolism* / Q000648:ultrastructure; D008722:Methods; D008854:Microscopy, Electron; D014176:Protein Biosynthesis; D014316:Tritium; D014364:Tryptophan / Q000378:metabolism*
D014316:Tritium; D014364:Tryptophan