A similar action to UV-irradiation and a preferential inhibition of DNA synthesis in E. coli by antitumor platinum compounds.
D002945:Cisplatin / Q000494:pharmacology*; D004269:DNA, Bacterial / Q000096:biosynthesis*; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism* / Q000528:radiation effects; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D008937:Mitomycins / Q000494:pharmacology; D011830:Radiation Effects; D014466:Ultraviolet Rays
D004269:DNA, Bacterial; D008937:Mitomycins; D002945:Cisplatin