A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction.
The results of a randomized controlled trial of a single daily dose of acetyl salicylic acid (aspirin) in the prevention of reinfarction in 1,239 men who had had a recent myocardial infarct were statistically inconclusive. Nevertheless, they showed a reduction in total mortality of 12% at six months and 25% at twelve months after admission to the trial. Further trials are urgently required to establish whether or not this effect is real.
D000367:Age Factors; D000368:Aged; D001241:Aspirin / Q000008:administration & dosage / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000517:prevention & control*; D010919:Placebos; D010973:Platelet Adhesiveness / Q000187:drug effects; D012008:Recurrence; D013997:Time Factors
D010919:Placebos; D001241:Aspirin