title: The dominant-lethal test: potential limitations and statistical considerations for safety evaluation.
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D003338:Corpus Luteum / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D010064:Embryo Implantation / Q000187:drug effects; D005069:Evaluation Studies as Topic; D005260:Female; D005313:Fetal Death / Q000139:chemically induced; D005503:Food Additives / Q000633:toxicity*; D005799:Genes, Dominant / Q000187:drug effects*; D005804:Genes, Lethal / Q000187:drug effects*; D005821:Genetic Techniques; D008297:Male; D009154:Mutation / Q000187:drug effects*; D009573:Nitrites / Q000633:toxicity; D011188:Potassium / Q000633:toxicity; D011247:Pregnancy; D051381:Rats; D013223:Statistics as Topic; D013997:Time Factors; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D005503:Food Additives; D009573:Nitrites; D011188:Potassium