Reaction of biological thiols with the tumor inhibitor jatrophone. Inhibition of RNA polymerase.
D000818:Animals; D002250:Carbon Radioisotopes; D002417:Cattle; D055598:Chemical Phenomena; D002621:Chemistry; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D012321:DNA-Directed RNA Polymerases / Q000037:antagonists & inhibitors*; D004224:Diterpenes; D004789:Enzyme Activation; D004926:Escherichia coli / Q000201:enzymology*; D004988:Ethers, Cyclic; D007700:Kinetics; D013058:Mass Spectrometry; D010936:Plant Extracts; D012265:Ribonucleotides; D012710:Serum Albumin, Bovine; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013438:Sulfhydryl Compounds; D014316:Tritium
D002250:Carbon Radioisotopes; D004224:Diterpenes; D004988:Ethers, Cyclic; D010936:Plant Extracts; D012265:Ribonucleotides; D013438:Sulfhydryl Compounds; D014316:Tritium; D012710:Serum Albumin, Bovine; C006386:jatrophone; D012321:DNA-Directed RNA Polymerases