Methylprednisolone protection against endotoxin in lead-sensitized mice.
Lead-sensitized BALB/c male mice are protected against Escherichia coli endotoxin by the intraperitoneal administration of 6alpha-methylprednisolone. This protection is dependent on time of administration of the methylprednisolone.
D000818:Animals; D000941:Antigens; D004731:Endotoxins / Q000494:pharmacology*; D004926:Escherichia coli / Q000276:immunology; D006967:Hypersensitivity / Q000276:immunology; D007854:Lead; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000494:pharmacology*; D051379:Mice; D008807:Mice, Inbred BALB C; D013997:Time Factors
D000941:Antigens; D004731:Endotoxins; D007854:Lead; D008775:Methylprednisolone