title: Loperamide (R 18 553), a novel type of antidiarrheal agent. Part 7: Clinical investigation. Efficacy and safety of loperamide in patients with severe chronic diarrhea.
mesh_terms: D000328:Adult; D000368:Aged; D000577:Amides / Q000008:administration & dosage / Q000627:therapeutic use; D000930:Antidiarrheals / Q000008:administration & dosage / Q000627:therapeutic use*; D002722:Chlorobenzenes / Q000008:administration & dosage / Q000627:therapeutic use; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D003093:Colitis, Ulcerative / Q000188:drug therapy; D003109:Colonic Diseases, Functional / Q000188:drug therapy; D003424:Crohn Disease / Q000188:drug therapy; D003967:Diarrhea / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D007540:Isonipecotic Acids / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009270:Naloxone / Q000494:pharmacology; D009570:Nitriles / Q000627:therapeutic use; D010880:Piperidines / Q000008:administration & dosage / Q000627:therapeutic use*; D010919:Placebos; D012025:Reflex, Pupillary / Q000187:drug effects
chemical_list: D000577:Amides; D000930:Antidiarrheals; D002722:Chlorobenzenes; D005765:Gastrointestinal Agents; D007540:Isonipecotic Acids; D009570:Nitriles; D010880:Piperidines; D010919:Placebos; D009270:Naloxone