title: Genetic studies on ribose 5-phosphate isomerase mutants of Escherichia coli K-12.
abstract: A gene for the constitutive ribosephosphate isomerase (rpiA) is highly cotransducible with serA at 56.2 min on the genetic linkage map of Escherichia coli K-12. Suppression of ribosephosphate isomerase A-negative mutants can occur by a regulator gene mutation permitting constitutive synthesis of the normally inducible ribosephosphate isomerase B.
mesh_terms: D002238:Carbohydrate Epimerases / Q000096:biosynthesis*; D002474:Cell-Free System; D002874:Chromosome Mapping; D003227:Conjugation, Genetic; D004926:Escherichia coli / Q000201:enzymology* / Q000378:metabolism; D005809:Genes, Regulator; D008040:Genetic Linkage; D009154:Mutation; D010428:Pentosephosphates; D011995:Recombination, Genetic; D012263:Ribonucleosides / Q000378:metabolism; D012266:Ribose / Q000378:metabolism; D014161:Transduction, Genetic
chemical_list: D010428:Pentosephosphates; D012263:Ribonucleosides; D012266:Ribose; D002238:Carbohydrate Epimerases