title: An aspartate transcarbamylase lacking catalytic subunit interactions. II. Regulatory subunits are responsible for the lack of co-operative interactions between catalytic sites. Drastic feedback inhibition does not restore these interactions.
mesh_terms: D000255:Adenosine Triphosphate / Q000494:pharmacology; D001221:Aspartate Carbamoyltransferase / Q000378:metabolism*; D001224:Aspartic Acid / Q000494:pharmacology; D001665:Binding Sites; D002384:Catalysis; D003597:Cytosine Nucleotides / Q000494:pharmacology; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli / Q000201:enzymology*; D005246:Feedback; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D046911:Macromolecular Substances; D008954:Models, Biological; D013053:Spectrophotometry; D015032:Zinc / Q000032:analysis
chemical_list: D003597:Cytosine Nucleotides; D046911:Macromolecular Substances; D001224:Aspartic Acid; D000255:Adenosine Triphosphate; D001221:Aspartate Carbamoyltransferase; D015032:Zinc