Antigens specific for human lymphocytic and myeloid leukemia cells: detection by nonhuman primate antiserums.
Primate antiserums to human leukemia cells can detect antigens specific for lymphocytic leukemia cells or antigens present on certain myeloid leukemia cells. The antigen specific for lymphocytic leukemia cells is destroyed by treatment with neuraminidase or trypsin. Tryptic digests of lymphocytic leukemia cells contain the antigen, which has a high molecular weight.
D000372:Agglutination Tests; D000818:Animals; D000937:Antigen-Antibody Reactions; D000951:Antigens, Neoplasm / Q000032:analysis*; D002478:Cells, Cultured; D003601:Cytotoxicity Tests, Immunologic; D004912:Erythrocytes / Q000276:immunology; D000882:Haplorhini / Q000276:immunology*; D006801:Humans; D007106:Immune Sera; D007945:Leukemia, Lymphoid / Q000276:immunology*; D007951:Leukemia, Myeloid / Q000276:immunology*; D015470:Leukemia, Myeloid, Acute / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008251:Macaca
D000951:Antigens, Neoplasm; D007106:Immune Sera