title: On the role of copper in activation of and catalysis by tryptophan-2,3-dioxygenase.
mesh_terms: D000818:Animals; D001205:Ascorbic Acid; D001667:Binding, Competitive; D002384:Catalysis; D002614:Chelating Agents; D003300:Copper / Q000032:analysis; D004789:Enzyme Activation; D006418:Heme / Q000032:analysis; D007501:Iron / Q000032:analysis; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D046911:Macromolecular Substances; D008956:Models, Chemical; D010618:Phenanthrolines; D011549:Pseudomonas / Q000201:enzymology*; D051381:Rats; D013045:Species Specificity; D013451:Sulfonic Acids; D013859:Thiocarbamates; D014364:Tryptophan; D014366:Tryptophan Oxygenase / Q000032:analysis / Q000037:antagonists & inhibitors / Q000302:isolation & purification
chemical_list: D002614:Chelating Agents; D046911:Macromolecular Substances; D010618:Phenanthrolines; D013451:Sulfonic Acids; D013859:Thiocarbamates; D006418:Heme; D003300:Copper; D014364:Tryptophan; D007501:Iron; D014366:Tryptophan Oxygenase; D001205:Ascorbic Acid