Fate of transforming deoxyribonucleic acid after uptake by competent Bacillus subtilis: nonrequirement of deoxyribonucleic acid replication for uptake and integration of transforming deoxyribonucleic acid.
Studies on transformation of Bacillus subtilis using the inhibitor 6-(p-hydroxyphenylazo)-uracil show that deoxyribonucleic acid (DNA) replication is not required for the uptake and integration of donor DNA and genetic markers.
D001391:Azo Compounds / Q000494:pharmacology; D001412:Bacillus subtilis / Q000378:metabolism*; D002247:Carbon Isotopes; D002499:Centrifugation, Density Gradient; D004261:DNA Replication / Q000187:drug effects; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000378:metabolism*; D011995:Recombination, Genetic; D013936:Thymidine / Q000378:metabolism; D014170:Transformation, Genetic; D014316:Tritium; D014498:Uracil / Q000494:pharmacology
D001391:Azo Compounds; D002247:Carbon Isotopes; D004269:DNA, Bacterial; D014316:Tritium; D014498:Uracil; D013936:Thymidine