Effect of elevated atmospheric pressure on antibiotic susceptibility of Staphylococcus aureus and Streptococcus pyogenes.
Staphylococcus aureus showed decreased susceptibility to penicillin, vancomycin, sodium cephalothin, and tetracycline, but increased susceptibility to sodium colistimethate, at a pressure of 68 atm in helium or helium-oxygen gas. Susceptibility of Streptococcus pyogenes was unchanged by pressurization.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001274:Atmospheric Pressure; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000187:drug effects*; D013297:Streptococcus pyogenes / Q000187:drug effects*
D000900:Anti-Bacterial Agents