Sporostatic and sporocidal properties of aqueous formaldehyde.
Aqueous formaldehyde is shown to exert both sporostatic and sporocidal effects on Bacillus subtilis spores. The sporostatic effect is a result of the reversible inhibition of spore germination occasioned by aqueous formaldehyde; the sporocidal effect is due to temperature-dependent inactivation of these spores in aqueous formaldehyde. The physicochemical state of formaldehyde in solution provides a framework with which to interpret both the sporostatic and sporocidal properties of aqueous formaldehyde.
D001412:Bacillus subtilis / Q000187:drug effects*; D005557:Formaldehyde / Q000494:pharmacology*; D007700:Kinetics; D013170:Spores / Q000187:drug effects*; D013171:Spores, Bacterial / Q000187:drug effects / Q000254:growth & development; D013696:Temperature
D005557:Formaldehyde