Oral immunization with polyvalent streptomycin-dependent Escherichia coli vaccine.
Streptomycin-dependent Escherichia coli serotypes O 111, O 55 and O 26 were used to vaccinate young patas monkeys against these organisms by the oral route. Five administrations of 10(10) cells in 3-day intervals gave almost full protection to the animals against challenge with 9 to 11 minimal infective doses of homologous virulent organisms for at least 1 month, whether the three serotypes were administered singly or simultaneously.
D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation; D000942:Antigens, Bacterial / Q000032:analysis; D001428:Bacterial Vaccines; D002859:Chromium Isotopes; D003720:Densitometry; D003967:Diarrhea / Q000517:prevention & control; D004926:Escherichia coli / Q000276:immunology*; D004927:Escherichia coli Infections / Q000276:immunology* / Q000517:prevention & control; D005243:Feces / Q000382:microbiology; D005827:Genetics, Microbial; D000882:Haplorhini; D007114:Immunization; D011863:Radioimmunoassay; D012703:Serotyping; D013307:Streptomycin; D013997:Time Factors; D014611:Vaccination
D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D002859:Chromium Isotopes; D013307:Streptomycin