[Studies in the synthesis of the antibiotics Gliotoxin, sporidesmin, Aranotin, and chaetocin. 3. Introduction of alkyl groups and sulfur functions into the 3- and 6-positions of 2.5-dioxopiperazines by electrophilic substitutions].
D000478:Alkylation; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D004220:Disulfides / Q000138:chemical synthesis; D007211:Indoles / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009904:Optical Rotation; D010082:Oxepins / Q000138:chemical synthesis; D010879:Piperazines / Q000138:chemical synthesis*; D013440:Sulfides / Q000138:chemical synthesis
D000900:Anti-Bacterial Agents; D004220:Disulfides; D007211:Indoles; D010082:Oxepins; D010879:Piperazines; D013440:Sulfides; C002511:chaetocin; C002500:aranotin
Syntheseversuche in der Reihe der 3.6-Epidithio-2.5-dioxo-piperazin-Antibiotika Gliotoxin, Sporidesmin, Aranotin und Chaetoxin. 3. Uber die elektrophile Einführung von Alkylgruppen und Schwefelfunktionen in den 2.5-Dioxo-piperazin-Kern.