L-Asparaginase production by Streptomyces griseus.
Streptomyces griseus ATCC 10137 synthesizes about 1 IU of L-asparaginase/100 ml of a 4% peptone medium. The enzyme has a pH optimum of 8.5 which is comparable to that of the L-asparaginase derived from Escherichia coli which has antitumor properties.
D001215:Asparaginase / Q000096:biosynthesis* / Q000378:metabolism; D003470:Culture Media; D006863:Hydrogen-Ion Concentration; D009113:Muramidase; D010100:Oxygen; D010461:Peptones; D013302:Streptomyces / Q000201:enzymology*; D013305:Streptomyces griseus / Q000201:enzymology / Q000254:growth & development; D014732:Vibration
D003470:Culture Media; D010461:Peptones; D009113:Muramidase; D001215:Asparaginase; D010100:Oxygen