Importance of the nucleolus in the initiation of DNA synthesis in mammalian cells. Studies with an ultraviolet microbeam and low concentrations of actinomycin D.
D000818:Animals; D001345:Autoradiography; D002294:Carcinoma, Squamous Cell; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D002466:Cell Nucleolus / Q000528:radiation effects; D003593:Cytoplasm / Q000528:radiation effects; D004247:DNA / Q000096:biosynthesis*; D004273:DNA, Neoplasm / Q000096:biosynthesis*; D003609:Dactinomycin / Q000494:pharmacology; D005347:Fibroblasts; D000882:Haplorhini; D006801:Humans; D007553:Isotope Labeling; D007668:Kidney; D007739:L Cells; D007822:Laryngeal Neoplasms; D051379:Mice / Q000196:embryology; D008938:Mitosis / Q000187:drug effects; D012334:RNA, Neoplasm / Q000096:biosynthesis; D011830:Radiation Effects; D013053:Spectrophotometry; D013936:Thymidine / Q000378:metabolism; D013997:Time Factors; D014316:Tritium; D014466:Ultraviolet Rays; D014529:Uridine / Q000378:metabolism
D004273:DNA, Neoplasm; D012334:RNA, Neoplasm; D014316:Tritium; D003609:Dactinomycin; D004247:DNA; D013936:Thymidine; D014529:Uridine