R factors in hospital infection.
In order to assess the clinical importance of R factors 524 "coliform" infections were studied in a general hospital. Of these, 95 were caused by Pseudomonas aeruginosa. Among the remaining 429, 43% were caused by drug-resistant enterobacteria; resistance was frequently multiple and determined by transmissible R factors. Choice of therapy was thus limited but in every case at least one antibiotic, effective in vitro, was still available.
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003428:Cross Infection; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy*; D004926:Escherichia coli / Q000187:drug effects; D005827:Genetics, Microbial; D006801:Humans; D007709:Klebsiella / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011511:Proteus / Q000187:drug effects; D011552:Pseudomonas Infections / Q000188:drug therapy*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000382:microbiology; D018805:Sepsis / Q000188:drug therapy; D013210:Staphylococcus / Q000472:pathogenicity; D013449:Sulfonamides / Q000627:therapeutic use; D013530:Surgical Wound Infection / Q000188:drug therapy; D014295:Trimethoprim / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000188:drug therapy; D014946:Wound Infection / Q000382:microbiology
D000900:Anti-Bacterial Agents; D013449:Sulfonamides; D014295:Trimethoprim