Lincomycin. 14. An improved synthesis and resolution of the antimalarial agent, 1'-demethyl-4'-depropyl-4'-(R)- and -(S)-pentylclindamycin hydrochloride (U-24, 729A).
D000818:Animals; D000962:Antimalarials / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D002981:Clindamycin / Q000138:chemical synthesis / Q000494:pharmacology / Q000627:therapeutic use; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D008034:Lincomycin / Q000138:chemical synthesis* / Q000494:pharmacology / Q000627:therapeutic use; D008288:Malaria / Q000188:drug therapy; D051379:Mice; D008826:Microbial Sensitivity Tests; D010962:Plasmodium berghei; D011514:Proteus vulgaris / Q000187:drug effects; D012475:Salmonella / Q000187:drug effects; D012505:Sarcina / Q000187:drug effects; D013203:Staphylococcal Infections / Q000188:drug therapy; D013210:Staphylococcus / Q000187:drug effects; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
D000962:Antimalarials; D002981:Clindamycin; D008034:Lincomycin