[The effect of exogenous DNA on the bodies and cells of eukaryotes].
A review of literature and the authors own data on specific and non-specific effect of DNA on the organism and eucaryote cells are presented. A conclusion is made that transduction and transformation in eucaryotes might be possible. It is confirmed by a great number of experimental data. The problem on mutagenic effect of DNA still remains disputable. The problem of DNA restriction in eucaryotes is absolutely unstudied and requires experimental development. A great theoretical and practical significance of the studies in the effect of exogenic DNA in higher organisms is emphasized.
D000650:Amnion; D000818:Animals; D001854:Bone Marrow Cells; D002645:Chickens; D004247:DNA / Q000494:pharmacology* / Q000627:therapeutic use; D004261:DNA Replication; D004330:Drosophila; D004372:Ducks; D005260:Female; D005818:Genetic Engineering; D006801:Humans; D051379:Mice; D009153:Mutagens; D009924:Organ Culture Techniques; D010063:Ovum; D010944:Plants; D011833:Radiation Injuries, Experimental / Q000188:drug therapy; D051381:Rats; D012513:Sarcoma, Experimental / Q000235:genetics; D012617:Sea Urchins; D014161:Transduction, Genetic; D014170:Transformation, Genetic
D009153:Mutagens; D004247:DNA
Deĭstvie ékzogennykh DNK na organizm i kletki éukariotov