Interferon system in mice infected with the scrapie agent.
Therapy with polyinosinic-polycytidylic acid did not protect scrapie-infected mice; scrapie infection did not affect the interferon response to polyinosinic . polycytidyl acid or Newcastle disease virus.
D000818:Animals; D005260:Female; D007372:Interferons / Q000096:biosynthesis*; D007928:Lethal Dose 50; D051379:Mice; D009522:Newcastle disease virus / Q000378:metabolism; D011070:Poly I-C / Q000494:pharmacology; D011328:Prions / Q000472:pathogenicity; D012608:Scrapie / Q000188:drug therapy / Q000378:metabolism* / Q000401:mortality; D012756:Sheep; D013997:Time Factors
D011328:Prions; D007372:Interferons; D011070:Poly I-C