Cultural characteristics of a cell line derived from an equine sarcoid.
A cell line, derived from a spontaneous equine connective tissue tumor (equine sarcoid), has been established. The morphological and growth characteristics indicative of malignant transformation of the cells include a disoriented, rapid growth and loss of contact inhibition. Further evidence of transformation is the agglutination of these cells by concanavalin A and their ability to divide in semisolid media.
D000362:Agar; D000372:Agglutination Tests; D000818:Animals; D002460:Cell Line; D002471:Cell Transformation, Neoplastic; D003208:Concanavalin A; D003470:Culture Media; D046508:Culture Techniques; D006736:Horses; D008297:Male; D012878:Skin Neoplasms; D014357:Trypsin
D003470:Culture Media; D003208:Concanavalin A; D000362:Agar; D014357:Trypsin