Metabolism of T4 bacteriophage ghost-infected cells. II. Do ghosts cause a generalized permeability change?
Ghosts appear to alter the barrier function of the cell membrane, allowing the release of phosphorylated sugars which normally cannot pass through the cell membrane, whereas phage do not. No increased influx of normally impermeable compounds is observed in the presence of ghosts, indicating that the loss of membrane function after ghost infection cannot be attributed to a generalized breakdown of the permeability barrier.
D000255:Adenosine Triphosphate / Q000378:metabolism; D002219:Carbamates / Q000378:metabolism; D002463:Cell Membrane Permeability; D002956:Citrulline / Q000096:biosynthesis; D003090:Coliphages; D004492:Edetic Acid / Q000494:pharmacology; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D005690:Galactose / Q000378:metabolism; D005827:Genetics, Microbial; D006027:Glycosides / Q000378:metabolism; D006868:Hydrolysis; D009154:Mutation; D009578:Nitrobenzenes / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism; D010759:Phosphorus Isotopes; D014050:Toluene / Q000494:pharmacology; D014764:Viral Proteins / Q000494:pharmacology*
D002219:Carbamates; D006027:Glycosides; D009578:Nitrobenzenes; D010710:Phosphates; D010759:Phosphorus Isotopes; D014764:Viral Proteins; D002956:Citrulline; D014050:Toluene; D000255:Adenosine Triphosphate; D004492:Edetic Acid; D005690:Galactose