title: Mechanism of tolerance development to organic nitrates.
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects; D004229:Dithiothreitol / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004361:Drug Tolerance; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D009130:Muscle, Smooth / Q000187:drug effects*; D009573:Nitrites / Q000378:metabolism; D005996:Nitroglycerin / Q000494:pharmacology*; D011817:Rabbits; D011955:Receptors, Drug / Q000187:drug effects*; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013997:Time Factors
chemical_list: D009573:Nitrites; D011955:Receptors, Drug; D013438:Sulfhydryl Compounds; D005996:Nitroglycerin; D004229:Dithiothreitol