Inhibition of sperm-egg interaction by specific antibody.
Treatment of hamster ova, in vitro, with ovary specific antibody interferes with sperm-egg interaction by inhibiting sperm attachment to the zona pellucida and subsequent zona penetration. This inhibition results from precipitation of the zona by the specific antibody.
D000818:Animals; D000906:Antibodies; D006224:Cricetinae; D005260:Female; D005306:Fertilization; D006821:Hyaluronoglucosaminidase / Q000378:metabolism; D007106:Immune Sera / Q000494:pharmacology; D007315:Insemination, Artificial; D008297:Male; D010053:Ovary / Q000276:immunology; D010063:Ovum / Q000166:cytology / Q000276:immunology* / Q000378:metabolism; D011817:Rabbits / Q000276:immunology; D013094:Spermatozoa / Q000276:immunology*
D000906:Antibodies; D007106:Immune Sera; D006821:Hyaluronoglucosaminidase