title: Aggregation of deoxyribonucleic acid and the helping effect in transformation.
abstract: Deoxyribonucleic acid aggregates in the presence of a component of Neopeptone at low ionic strength and thereby loses its ability to bind to competent bacteria. The reversible and concentration-dependent nature of this aggregation is the basis of the helping effect in transformation.
mesh_terms: D001412:Bacillus subtilis; D003470:Culture Media; D004269:DNA, Bacterial / Q000378:metabolism; D046911:Macromolecular Substances; D009994:Osmolar Concentration; D010759:Phosphorus Isotopes; D013291:Streptococcus / Q000378:metabolism; D014170:Transformation, Genetic
chemical_list: D003470:Culture Media; D004269:DNA, Bacterial; D046911:Macromolecular Substances; D010759:Phosphorus Isotopes