14 C-glucose oxidation in whole blood: a clinical assay for phagocyte dysfunction.
A screening test for chronic granulomatous disease is described; it is based on abnormal oxidation of glucose-1-(14)C to (14)CO(2) during phagocytosis by leukocytes in whole blood.
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism*; D001793:Blood Preservation; D002245:Carbon Dioxide / Q000096:biosynthesis; D002247:Carbon Isotopes; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D010084:Oxidation-Reduction; D010585:Phagocyte Bactericidal Dysfunction / Q000097:blood / Q000175:diagnosis*; D010587:Phagocytosis
D001786:Blood Glucose; D002247:Carbon Isotopes; D002245:Carbon Dioxide