Proton/sodium ion antiport in Escherichia coli.
In anaerobic suspensions of Escherichia coli, after H(+) ions have been translocated outwards across the plasma membrane by a respiratory pulse, re-equilibration is catalysed by Na(+). The sudden addition of a Na(+) salt causes the effective outward translocation of H(+) by an electroneutral process. We conclude that the plasma membrane of E. coli contains a Na(+)/H(+) antiport system that normally translocates Na(+) outwards under the influence of an inwardly directed H(+)-activity gradient.
D001693:Biological Transport, Active; D002462:Cell Membrane / Q000378:metabolism; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D010101:Oxygen Consumption; D011522:Protons; D012964:Sodium / Q000378:metabolism*; D014475:Uncoupling Agents / Q000494:pharmacology
D011522:Protons; D014475:Uncoupling Agents; D012964:Sodium