Metabolism and pharmacokinetics of a new nonsteroid, anti-inflammatory agent, 2-(3-chloro-o-toluidino) nicotinic acid (clonixin) in rats, dogs and monkeys.
D000818:Animals; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D002845:Chromatography; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005243:Feces / Q000032:analysis; D005260:Female; D005965:Glucuronates / Q000302:isolation & purification; D000882:Haplorhini; D008251:Macaca; D008297:Male; D008962:Models, Theoretical; D009539:Nicotinic Acids / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D051381:Rats; D013056:Spectrophotometry, Ultraviolet; D013431:Sulfates / Q000302:isolation & purification; D014052:Toluidines / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism*; D014316:Tritium
D000893:Anti-Inflammatory Agents; D005965:Glucuronates; D009539:Nicotinic Acids; D013431:Sulfates; D014052:Toluidines; D014316:Tritium