title: Linkage studies on DDT and dieldrin resistance in species A and species B of the Anopheles gambiae complex.
abstract: Linkage studies in A. gambiae species A showed that the two autosomal markers diamond (Di) and collarless (c) belonged to different linkage groups: Di on linkage group 2 and c on linkage group 3. With the aid of the two markers it was possible to establish the linkage relationship between the genes for DDT resistance and for the two types of dieldrin resistance. The DDT resistance gene in species A assorted independently of c and was found to be linked with Di at a map distance of 26.3 units. The genes for the two types of dieldrin resistance, dominant and incompletely dominant, were found to be allelic. The major gene for dieldrin resistance was shown to be linked with the gene for DDT resistance in linkage group 2 at a map distance of 35.3 units. This suggested that Di and the dieldrin resistance gene were some 61.6 units apart.
mesh_terms: D000818:Animals; D000852:Anopheles; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D003634:DDT; D004026:Dieldrin; D005799:Genes, Dominant; D005816:Genetic Complementation Test; D008040:Genetic Linkage; D007305:Insecticide Resistance; D013045:Species Specificity
chemical_list: D003634:DDT; D004026:Dieldrin