Rickettsial hemolysis: adsorption of rickettsiae to erythrocytes.
The hemolysis of sheep red blood cells by Rickettsia prowazeki has been characterized. A requirement for the adsorption of the rickettsia to the erythrocyte was indicated. No indication of the production of a soluble hemolysin was observed. Neither adsorption nor hemolysis can proceed at 0 C. The hemolytic process is rapid with a half-time of less than 30 min, and both the rate and extent are proportional to the number of rickettsiae present.
D000818:Animals; D001431:Bacteriological Techniques; D001798:Blood Proteins / Q000032:analysis; D004912:Erythrocytes / Q000276:immunology*; D006382:Hemadsorption; D006461:Hemolysis; D008854:Microscopy, Electron; D012283:Rickettsia prowazekii / Q000276:immunology*; D012756:Sheep / Q000276:immunology
D001798:Blood Proteins