Human immunoglobulin specificity after group B arbovirus infections.
Sera obtained during a dengue-2 epidemic from individuals with primary or secondary group B arbovirus infections contained cross-reactive antibody against several viruses in this group. Hemagglutination-inhibition antibody titers of the immunoglobulin M fractions from these sera revealed a rise in antibody specific for dengue-2. The acute and convalescent sera in over half of the secondary infection group also had low-level unchanging immunoglobulin M antibody titers to yellow fever which implicated yellow fever immunization as the primary infection.
D000918:Antibody Specificity; D001102:Arbovirus Infections / Q000276:immunology*; D001103:Arboviruses / Q000302:isolation & purification; D003429:Cross Reactions; D003716:Dengue Virus / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D006462:Hemolytic Plaque Technique; D006801:Humans; D005779:Immunodiffusion; D007074:Immunoglobulin G / Q000032:analysis / Q000302:isolation & purification; D007075:Immunoglobulin M / Q000032:analysis* / Q000302:isolation & purification; D008623:Mercaptoethanol / Q000494:pharmacology; D009500:Neutralization Tests; D013997:Time Factors; D010948:Viral Plaque Assay
D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008623:Mercaptoethanol