Characterization of a plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain Streptococcus pyogenes.
A plasmid determining resistance to erythromycin, lincomycin, and vernamycin B(alpha) was isolated from a strain of Streptococcus pyogenes. The plasmid has a molecular weight of approximately 17 x 10(6) and is present to the extent of one to two copies per chromosomal genome equivalent.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004269:DNA, Bacterial / Q000302:isolation & purification; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology*; D005111:Extrachromosomal Inheritance; D007783:Lactones / Q000494:pharmacology; D008034:Lincomycin / Q000494:pharmacology*; D010456:Peptides, Cyclic / Q000494:pharmacology; D013297:Streptococcus pyogenes / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D007783:Lactones; D010456:Peptides, Cyclic; D004917:Erythromycin; D008034:Lincomycin