A rapid micro-method for the screening and measurement of barbiturates and related compounds in plasma by gas-liquid chromatography.
A rapid gas-chromatographic method has been developed for the determination of butobarbitone, amylobarbitone, hexabarbitone, pentobarbitone, quinalbarbitone, phenobarbitone glutethimide, and methaqualone in ;finger-prick' samples of plasma. This has been applied to the analysis of some of these drugs in plasma taken from patients after therapeutic dosage and over-dosage.
D000654:Amobarbital / Q000097:blood; D000818:Animals; D001463:Barbiturates / Q000097:blood*; D001800:Blood Specimen Collection; D002417:Cattle; D002849:Chromatography, Gas; D005069:Evaluation Studies as Topic; D005984:Glutethimide / Q000097:blood*; D006591:Hexobarbital / Q000097:blood; D006801:Humans; D008702:Methaqualone / Q000097:blood*; D008722:Methods; D008832:Microchemistry; D010424:Pentobarbital / Q000097:blood; D010634:Phenobarbital / Q000097:blood; D012631:Secobarbital / Q000097:blood; D013997:Time Factors
D001463:Barbiturates; D012631:Secobarbital; D008702:Methaqualone; D006591:Hexobarbital; D005984:Glutethimide; D000654:Amobarbital; D010424:Pentobarbital; D010634:Phenobarbital