The active groups in the structure of thiamine tetrahydrofurfuryldisulfide in its anti-potassium, anti-quinidine, and anti-acetylcholine effects on guinea-pig atria.
D000109:Acetylcholine / Q000037:antagonists & inhibitors*; D000818:Animals; D004220:Disulfides / Q000494:pharmacology*; D004558:Electric Stimulation; D005663:Furans / Q000494:pharmacology; D006168:Guinea Pigs; D006325:Heart Atria / Q000187:drug effects*; D066298:In Vitro Techniques; D008297:Male; D011188:Potassium / Q000037:antagonists & inhibitors*; D011743:Pyrimidines / Q000494:pharmacology*; D011802:Quinidine / Q000037:antagonists & inhibitors*; D012849:Sinoatrial Node / Q000187:drug effects; D013329:Structure-Activity Relationship; D013440:Sulfides / Q000494:pharmacology
D004220:Disulfides; D005663:Furans; D011743:Pyrimidines; D013440:Sulfides; D011802:Quinidine; D000109:Acetylcholine; D011188:Potassium