Surface-bonded antimicrobial activity of an organosilicon quaternary ammonium chloride.
The hydrolysis product of 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride exhibited antimicrobial activity against a broad range of microorganisms while chemically bonded to a variety of surfaces. The chemical was not removed from surfaces by repeated washing with water, and its antimicrobial activity could not be attributed to a slow release of the chemical, but rather to the surface-bonded chemical.
D000085:Acetates; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001548:Benzalkonium Compounds / Q000494:pharmacology; D002247:Carbon Isotopes; D002470:Cell Survival; D002482:Cellulose; D055598:Chemical Phenomena; D002621:Chemistry; D056890:Eukaryota / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D005898:Glass; D003368:Gossypium; D006868:Hydrolysis; D008826:Microbial Sensitivity Tests; D012828:Silicones / Q000494:pharmacology*; D013045:Species Specificity; D015003:Yeasts / Q000187:drug effects
D000085:Acetates; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001548:Benzalkonium Compounds; D002247:Carbon Isotopes; D012828:Silicones; D002482:Cellulose