To the editor: ketamine may interact with barbiturate premedication in producing delayed awakening from anesthesia and significant respiratory depression.
D000771:Anesthesia, Intravenous / Q000009:adverse effects*; D001463:Barbiturates / Q000009:adverse effects*; D002648:Child; D004347:Drug Interactions; D006801:Humans; D007649:Ketamine / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D011183:Postoperative Complications / Q000139:chemically induced*; D011229:Preanesthetic Medication / Q000009:adverse effects*; D012131:Respiratory Insufficiency / Q000139:chemically induced*
D001463:Barbiturates; D007649:Ketamine