Memory traces: experimental separation by cycloheximide and electroconvulsive shock.
Mice given cycloheximide or saline were trained with a single trial. Electroconvulsive shock was administered to both groups at various times after training. Cycloheximide led to memory that decayed with time. Cycloheximide plus electroconvulsive shock produced complete amnesia at times when neither treatment alone produced amnesia. Only two types of processes appear to support memory storage in our study.
D000647:Amnesia / Q000139:chemically induced / Q000209:etiology; D000818:Animals; D003513:Cycloheximide / Q000494:pharmacology*; D004597:Electroshock; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects; D051379:Mice; D013997:Time Factors
D003513:Cycloheximide