Para-substituted N-acetyl-L(S)- and -D(R)- -amino-N-phenylsuccinimides and -glutarimides. Substituent effects on stereoselective anticonvulsant activity.
D000085:Acetates / Q000138:chemical synthesis / Q000627:therapeutic use; D000596:Amino Acids / Q000138:chemical synthesis / Q000627:therapeutic use; D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000627:therapeutic use; D002942:Circular Dichroism; D004597:Electroshock; D005977:Glutarates / Q000138:chemical synthesis* / Q000627:therapeutic use; D007094:Imides / Q000138:chemical synthesis* / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009905:Optical Rotatory Dispersion; D010433:Pentylenetetrazole / Q000037:antagonists & inhibitors; D011760:Pyrrolidinones / Q000138:chemical synthesis*; D012640:Seizures / Q000517:prevention & control; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013388:Succinimides / Q000138:chemical synthesis / Q000627:therapeutic use
D000085:Acetates; D000596:Amino Acids; D000927:Anticonvulsants; D005977:Glutarates; D007094:Imides; D011760:Pyrrolidinones; D013388:Succinimides; D010433:Pentylenetetrazole