Production of kinins in bovine anaphylactic shock.
Calves were sensitized by subcutaneous injection of horse serum in Freund's adjuvant. Subsequent challenge with intravenous horse serum induced increased blood kinin activity. This kinin activation correlated with the protracted fall in systemic blood pressure seen in the same animals.
D000707:Anaphylaxis / Q000097:blood*; D000818:Animals; D001769:Blood; D001794:Blood Pressure; D001920:Bradykinin / Q000097:blood; D002417:Cattle; D005620:Freund's Adjuvant; D006736:Horses / Q000276:immunology; D007705:Kinins / Q000096:biosynthesis*; D008297:Male; D013997:Time Factors
D007705:Kinins; D005620:Freund's Adjuvant; D001920:Bradykinin