Dimethylaminoethyl 2,2-diphenylvalerate HCl (SKF 525-A)--in vivo and in vitro effects of metabolism by rat liver microsomes--formation of an oxygenated complex.
D000632:Aminopyrine / Q000037:antagonists & inhibitors / Q000378:metabolism; D000814:Aniline Compounds / Q000037:antagonists & inhibitors / Q000378:metabolism; D000818:Animals; D001711:Biotransformation / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D003640:Dealkylation; D005260:Female; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D009929:Organ Size; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism; D010089:Oxidoreductases, N-Demethylating; D004364:Pharmaceutical Preparations / Q000378:metabolism; D011335:Proadifen / Q000008:administration & dosage / Q000378:metabolism*; D051381:Rats; D013057:Spectrum Analysis; D013997:Time Factors
D000814:Aniline Compounds; D004364:Pharmaceutical Preparations; D000632:Aminopyrine; D003577:Cytochrome P-450 Enzyme System; D011335:Proadifen; D010088:Oxidoreductases; D010089:Oxidoreductases, N-Demethylating