In vitro susceptibility of isolates of Aspergillus fumigatus and Sporothrix schenckii to amphotericin B.
The in vitro susceptibility of 21 isolates of Aspergillus fumigatus and 12 isolates of Sporothrix schenckii to amphotericin B was determined. The minimal inhibitory concentration (MIC) for the A. fumigatus isolates ranged from 0.14 to 0.6 mug of drug per ml. The mean MIC for the 21 isolates was 0.33 mug per ml. The MIC for the 12 S. schenckii isolates ranged from 0.68 to 2.12 mug of drug per ml, with a mean MIC of 1.38 mug per ml.
D000666:Amphotericin B / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects*
D000666:Amphotericin B