title: Maintenance of genetic variation with a frequency-dependent selection model as compared to the overdominant model.
abstract: A frequency-dependent selection model proposed by Huang, Singh and Kojima (1971) was found to be more effective at maintaining genetic variation in a finite population than the overdominant model. The fourth moment parameter of the distribution of unfixed states showed that there was a more platykurtic distribution for the frequency-dependent model. This agreed well with the expected gene frequency change found for an infinite population.
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D005787:Gene Frequency; D005799:Genes, Dominant; D014644:Genetic Variation; D006801:Humans; D008954:Models, Biological; D012641:Selection, Genetic