Galactorrhoea: successful treatment with reduction of plasma prolactin levels by brom-ergocryptine.
In five patients with inappropriate lactation and amenorrhoea or impotence brom-ergocryptine was found to suppress the lactation and to diminish the raised plasma prolactin levels. The responses to treatment suggest that there may be an inverse relationship between prolactin secretion and gonadotrophin secretion in man.
D000328:Adult; D000568:Amenorrhea / Q000188:drug therapy; D000818:Animals; D001681:Biological Assay; D001966:Bromine; D007172:Erectile Dysfunction / Q000188:drug therapy; D004876:Ergot Alkaloids / Q000627:therapeutic use*; D005260:Female; D006065:Gonadotropins, Pituitary / Q000378:metabolism; D006801:Humans; D007775:Lactation Disorders / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008321:Mammary Glands, Animal; D011247:Pregnancy; D011388:Prolactin / Q000097:blood* / Q000378:metabolism; D011817:Rabbits; D011863:Radioimmunoassay
D004876:Ergot Alkaloids; D006065:Gonadotropins, Pituitary; D011388:Prolactin; D001966:Bromine