Norephedrines as metabolites of ( 14 C)amphetamine in urine in man.
(+/-)-[(14)C]Amphetamine sulphate (20mg) was administered orally to each of two human male subjects, and 80-85% of the (14)C was excreted in the urine in 2 days. The metabolites in the first day's urine were examined quantitatively. Apart from the metabolites previously described (Dring et al., 1970), norephedrine (2.2 and 2.6% of dose in the two subjects respectively) and 4-hydroxynorephedrine (0.3 and 0.4% of dose in the two subjects respectively) were also found.
D000605:Amino Alcohols / Q000652:urine*; D000661:Amphetamine / Q000378:metabolism*; D002247:Carbon Isotopes; D006801:Humans; D008297:Male; D010627:Phenethylamines / Q000652:urine*; D010665:Phenylpropanolamine / Q000378:metabolism / Q000652:urine; D013566:Sympathomimetics / Q000652:urine*
D000605:Amino Alcohols; D002247:Carbon Isotopes; D010627:Phenethylamines; D013566:Sympathomimetics; D010665:Phenylpropanolamine; D000661:Amphetamine