Antigenic cross-reactivity of staphylococcal enterotoxins.
The antigenic cross-reactivity of staphylococcal enterotoxins types A, B, and C was assessed using anti-A and anti-B antitoxins in the solid-phase radioimmunoassay test. Heterologous reactions were observed. At the 33% inhibition level, B was 18,000 and 5,400 times more effective as an inhibitor in its homologous system than were the heterologous enterotoxins A and C, respectively. Similarly, in the A system, A enterotoxin was 55,000 and 25,000 times more effective than were B and C toxins, respectively, in inhibiting A-anti-A reactions.
D000818:Animals; D000937:Antigen-Antibody Reactions; D000942:Antigens, Bacterial; D000992:Antitoxins; D001666:Binding Sites, Antibody; D002417:Cattle / Q000276:immunology; D003429:Cross Reactions; D004768:Enterotoxins; D007456:Iodine Isotopes; D011863:Radioimmunoassay; D012710:Serum Albumin, Bovine; D012711:Serum Albumin, Radio-Iodinated; D013210:Staphylococcus / Q000276:immunology*
D000942:Antigens, Bacterial; D000992:Antitoxins; D004768:Enterotoxins; D007456:Iodine Isotopes; D012711:Serum Albumin, Radio-Iodinated; D012710:Serum Albumin, Bovine