A study of the effect of some drugs which cause agranulocytosis on the biosynthesis of pyrimidines in human granulocytes.
D000380:Agranulocytosis / Q000139:chemically induced*; D000581:Amidohydrolases / Q000037:antagonists & inhibitors; D001221:Aspartate Carbamoyltransferase / Q000037:antagonists & inhibitors; D001798:Blood Proteins / Q000032:analysis; D002231:Carbimazole / Q000494:pharmacology; D002247:Carbon Isotopes; D002262:Carboxy-Lyases / Q000037:antagonists & inhibitors; D002701:Chloramphenicol / Q000494:pharmacology; D002746:Chlorpromazine / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007962:Leukocytes / Q000187:drug effects / Q000378:metabolism*; D008779:Methylthiouracil / Q000494:pharmacology; D009963:Orotic Acid; D010088:Oxidoreductases / Q000037:antagonists & inhibitors; D010430:Pentosyltransferases / Q000037:antagonists & inhibitors; D010653:Phenylbutazone / Q000494:pharmacology; D011743:Pyrimidines / Q000096:biosynthesis*; D014732:Vibration
D001798:Blood Proteins; D002247:Carbon Isotopes; D011743:Pyrimidines; D009963:Orotic Acid; D002701:Chloramphenicol; D002231:Carbimazole; D010088:Oxidoreductases; D001221:Aspartate Carbamoyltransferase; D010430:Pentosyltransferases; D000581:Amidohydrolases; D002262:Carboxy-Lyases; D010653:Phenylbutazone; D008779:Methylthiouracil; D002746:Chlorpromazine