Evidence for the presence of a distinct subsite for binding the distal carboxyl group of dicarboxylate substrates and its role in the catalytic activity of aspartate aminotransferase.
D000409:Alanine / Q000494:pharmacology; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D001665:Binding Sites; D002264:Carboxylic Acids / Q000378:metabolism*; D002712:Chlorides; D005561:Formates / Q000494:pharmacology; D007527:Isoenzymes / Q000378:metabolism; D007700:Kinetics; D008954:Models, Biological; D009206:Myocardium / Q000201:enzymology; D011485:Protein Binding; D011489:Protein Denaturation; D013056:Spectrophotometry, Ultraviolet; D013552:Swine; D013997:Time Factors
D002264:Carboxylic Acids; D002712:Chlorides; D005561:Formates; D007527:Isoenzymes; D001219:Aspartate Aminotransferases; D000409:Alanine